Spreadsheet: 7661fab9-b80f-410b-b0b7-712c1ab716ff
Sheet: Sheet1

Test Referenced | Entry Type | Mayo ID | Description | Reporting Description | Method | Collection Container | Temperature | Stability | [NAME] | Unit of Measure | [NAME] | Minimum Volume | Reject Due To | Reference Values | Days/Times Performed | Analytic Time | Maximum Lab Time | CPT Units | CPT Code | LOINC® Code | LOINC® Attributes | Always Performed | Orderable Separately | Performing Location
PNEOE | Test | PNEOE | Paraneoplastic Autoantibody Evaluation, Spinal Fluid | [NAME],CSF | ANN1C/3852, ANN2C/7472, ANN3C/21633, PCA1C/3988, PCA2C/21632, PCTRC/21631, AMPHC/5906, CRMC/21650, AGN1C/89079, NMOC/83936: Indirect Immunofluorescence Assay (IFA) WBNC/21764, CRMWC/21747, ABLTC/89380: Western Blot | Plastic vial: PlV |  |  | 4 | mL | Container/Tube: Sterile vial [NAME]: 4 mL Additional Information: Include name, phone number, mailing address, and e-mail address (if applicable) of ordering physician. Forms: If not ordering electronically, submit a General Request Form (Supply T239) with the specimen. | 3 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | ANTINEURONAL NUCLEAR ANTIBODY-Type 1 (ANNA-1) Negative at <1:2   ANTINEURONAL NUCLEAR ANTIBODY-Type 2 (ANNA-2) Negative at <1:2   ANTINEURONAL NUCLEAR ANTIBODY-Type 3 (ANNA-3) Negative at <1:2   ANTI-GLIAL/NEURONAL NUCLEAR ANTIBODY, Type 1 (AGNA-1) Negative at <1:2   PURKINJE CELL CYTOPLASMIC ANTIBODY, Type 1 (PCA-1) Negative at <1:2   PURKINJE CELL CYTOPLASMIC ANTIBODY, Type 2 (PCA-2) Negative at <1:2   PURKINJE CELL CYTOPLASMIC ANTIBODY, Type Tr (PCA-Tr) Negative at <1:2   AMPHIPHYSIN ANTIBODY  Negative at <1:2   CRMP-5-IgG Negative at <1:2 Note: Titers lower than 1:2 are detectable by recombinant CRMP-5 Western blot analysis. CRMP-5 Western blot analysis will be done on request on stored spinal fluid (held 4 weeks). This supplemental testing is recommended in cases of chorea, vision loss, cranial neuropathy, and myelopathy. Call the Neuroimmunology Laboratory at [PHONE] or [PHONE] to request CRMP-5 Western blot.   Neuron-restricted patterns of IgG staining that do not fulfill criteria for the listed autoantibodies may be reported as "unclassified antineuronal IgG." If detected, newly identified autoantibody specificities may be reported. Complex patterns that include non-neuronal elements may be reported as "uninterpretable."   NEUROMYELITIS OPTICA (NMO)/AQUAPORIN-4-IgG CELL-BINDING ASSAY Negative | ANNA-1: Monday through Friday; 11:30 a.m.  ANNA-2: Monday through Friday; 11:30 a.m. ANNA-3: Monday through Friday; 11:30 a.m. AGNA-1: Monday through Friday; 11:30 am PCA-1: Monday through Friday; 11:30 a.m. PCA-2: Monday through Friday; 11:30 a.m.   [NAME] | 3 days if neg/5 days if pos | 8 days |  | Profile |  |  |  |  | Rochester
PNEOE | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
PNEOE | Component | ANN1C | Antineuronal Nuclear Antibody-Type 1 (ANNA-1), [NAME] | Anti-Neuronal Nuclear Ab, Type 1 | Indirect Immunofluorescence (IFA) | Plastic vial: PlV |  |  | 2 | mL | [NAME]: 2 mL Collection Instructions: Send specimen refrigerated. Additional Information: Serum is preferred. Spinal fluid is particularly useful if positive antibody or interfering antibodies are present. | 2.0 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative at <1:2  Neuron-restricted patterns of IgG staining that do not fulfill criteria for ANNA-1 may be reported as "unclassified antineuronal IgG." Complex patterns that include nonneuronal elements may be  reported as "uninterpretable." | Monday through Friday; 11:30 a.m. | 5 days if positive/3 days if negative | 8 days | 1 | 86256 |  |  | Yes | No
ANN1C | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
ANN1C | Result | 3852 | ANNA-1, CSF | ANNA-1, CSF | Alphanumeric |  |  |  |  | titer |  |  |  |  |  |  |  |  |  | 24400-4 | Neuronal nuclear type 1 Ab:Titr:Pt:CSF:Qn:IF
PNEOE | Component | ANN2C | Antineuronal Nuclear Antibody-Type 2 (ANNA-2), [NAME] | Anti-Neuronal Nuclear Ab, Type 2 | Indirect Immunofluorescence (IFA) | Plastic vial: PlV |  |  | 2 | mL | [NAME]: 2 mL Collection Instructions: Send specimen refrigerated. Additional Information: Serum is preferred. Spinal fluid is particularly useful if interfering antibodies are present. | 2.0 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative at <1:2 Neuron-restricted patterns of IgG staining that do not fulfill criteria for ANNA-2 may be reported as "unclassified antineuronal IgG." Complex patterns that include nonneuronal elements may be reported as "uninterpretable." | Monday through Friday; 11:30 a.m. | 5 days if positive/3 days if negative | 8 days | 1 | 86256 |  |  | Yes | No
ANN2C | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
ANN2C | Result | 7472 | ANNA-2, CSF | ANNA-2, CSF | Alphanumeric |  |  |  |  | titer |  |  |  |  |  |  |  |  |  | 24401-2 | Neuronal nuclear type 2 Ab:Titr:Pt:CSF:Qn:IF
PNEOE | Component | ANN3C | Antineuronal Nuclear Antibody-Type 3 (ANNA-3), [NAME] | Anti-Neuronal Nuclear Ab, Type 3 | Indirect Immunofluorescence (IFA) | [NAME], leak proof vial: ScwLkPf |  |  | 2 | mL | [NAME]: 2 mL Collection Instructions: Send specimen refrigerated. | 2.0 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative at <1:2 Neuron-restricted patterns of IgG staining that do not fulfill criteria for ANNA-3 may be reported as "unclassified antineuronal IgG." Complex patterns that include nonneuronal elements may be reported as "uninterpretable." | Monday through Friday; 11:30 a.m. | 3 days if negative; 5 days if positive | 8 days | 1 | 86256 |  |  | Yes | No
ANN3C | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
ANN3C | Result | 21633 | ANNA-3, CSF | ANNA-3, CSF | Alphanumeric |  |  |  |  | titer |  |  |  |  |  |  |  |  |  | 35144-5 | Neuronal nuclear type 3 Ab:Titr:Pt:CSF:Qn:
PNEOE | Component | AGN1C | Anti-Glial/Neuronal Nuclear Antibody-Type 1 (AGNA-1), [NAME] | Anti-Glial Nuclear Ab, Type 1 | Indirect Immunofluorescence Assay (IFA) |  |  |  | 4 | mL | [NAME]: 2 mL Collection Instructions: Send specimen refrigerated. Additional Information: Serum is preferred. Spinal fluid is particularly useful if interfering antibodies are present. | 1.0 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative at <1:2 | Monday through Friday; 11:30 a.m. | 5 days if positive/3 days if negative | 8 days | 1 | 86256 |  |  | Yes | No
AGN1C | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
AGN1C | Result | 89079 | AGNA-1, CSF | AGNA-1, CSF | Alphanumeric |  |  |  |  | titer |  |  |  |  |  |  |  |  |  | 53714-2 | Glial nuclear type 1 Ab:Titr:Pt:CSF:Qn:
PNEOE | Component | PCA1C | Purkinje Cell Cytoplasmic Antibody, Type 1 (PCA-1), [NAME] | Purkinje Cell Cytoplasmic Ab Type 1 | Indirect Immunofluorescence (IFA) | Plastic vial: PlV |  |  | 2 | mL | [NAME]: 2 mL Collection Instructions: Send specimen refrigerated. Additional Information: 1. Serum is preferred. When interfering antibodies are present in serum, spinal fluid is particularly useful. 2. Include name, phone number, mailing address, and e-mail address (if applicable) of ordering physician. | 2 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative at <1:2 Neuron-restricted patterns of IgG staining that do not fulfill criteria for PCA-1 may be reported as "unclassified antineuronal IgG." Complex patterns that include nonneuronal elements may be reported as "uninterpretable." | Monday through Friday; 11:30 a.m. | 3 days if negative/5 days if positive | 8 days | 1 | 86256 |  |  | Yes | No
PCA1C | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
PCA1C | Result | 3988 | PCA-1, CSF | PCA-1, CSF | Alphanumeric |  |  |  |  | titer |  |  |  |  |  |  |  |  |  | 14248-9 | Purkinje cells Ab:Titr:Pt:CSF:Qn:IF
PNEOE | Component | PCA2C | Purkinje Cell Cytoplasmic Antibody, Type 2 (PCA-2), [NAME] | Purkinje Cell Cytoplasmic Ab Type 2 | Indirect Immunofluorescence (IFA) | [NAME], leak proof vial: ScwLkPf |  |  | 4 | mL | [NAME]: 4 mL Collection Instructions: Send specimen refrigerated. Additional Information: Serum is preferred. When interfering antibodies are present in serum, spinal fluid is particularly useful. | 1 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative at <1:2 Neuron-restricted patterns of IgG staining that do not fulfill criteria for PCA-2 may be reported as "unclassified antineuronal IgG." Complex patterns that include non-neuronal elements may be reported as "uninterpretable." | Monday through Friday; 11:30 a.m. | 3 days if negative; 5 days if positive | 8 days | 1 | 86256 |  |  | Yes | No
PCA2C | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
PCA2C | Result | 21632 | PCA-2, CSF | PCA-2, CSF | Alphanumeric |  |  |  |  | titer |  |  |  |  |  |  |  |  |  | 35143-7 | Purkinje cells type 2 Ab:Titr:Pt:CSF:Qn:
PNEOE | Component | PCTRC | Purkinje Cell Cytoplasmic Antibody, Type Tr (PCA-Tr), [NAME] | Purkinje Cell Cytoplasmc Ab Type Tr | Indirect Immunofluorescence (IFA) | Plastic vial: PlV |  |  | 4 | mL | Only orderable as part of a profile. For further information see PNEOE / Paraneoplastic Autoantibody Evaluation, Spinal Fluid.  [NAME]: 4 mL Additional Information: Serum is preferred. When interfering antibodies are present in serum, spinal fluid is particularly useful. | 1 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative at <1:2  Neuron-restricted patterns of IgG staining that do not fulfill criteria for PCA-Tr may be reported as "unclassified antineuronal IgG." Complex patterns may be reported as "uninterpretable." | Monday through Friday; 11:30 a.m. | 3 days if negative; 5 days if positive | 8 days | 1 | 86256 |  |  | Yes | No
PCTRC | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
PCTRC | Result | 21631 | PCA-Tr, CSF | PCA-Tr, CSF | Alphanumeric |  |  |  |  | titer |  |  |  |  |  |  |  |  |  | 51748-2 | Purkinje cells type Tr Ab:Titr:Pt:CSF:Qn:
PNEOE | Component | AMPHC | Amphiphysin Antibody Assay, Spinal Fluid | [NAME], CSF | Indirect Immunofluorescence (IFA) | Plastic vial: PlV |  |  | 2 | mL | [NAME]: 2 mL Collection Instructions: Send specimen refrigerated. Additional Information: 1. Serum is preferred. Spinal fluid is particularly useful if positive antibody or interfering antibodies are present. 2. Please provide name, phone number, mailing address, and e-mail address (if applicable) of ordering physician. | 2.0 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | <1:2 | Monday through Friday; 11:30 a.m. | 5 days if positive/3 days if negative | 8 days | 1 | 86256 |  |  | Yes | No
AMPHC | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
AMPHC | Result | 5906 | [NAME], CSF | [NAME], CSF | Alphanumeric |  |  |  |  | titer |  |  |  |  |  |  |  |  |  | 35142-9 | [NAME]:Titr:Pt:CSF:Qn:
PNEOE | Component | CRMC | [NAME] Protein-5 Neuronal (CRMP-5-IgG), [NAME] | CRMP-5-IgG, CSF | Indirect Immunofluorescence (IFA) | [NAME], leak proof vial: ScwLkPf |  |  | 4 | mL | [NAME]: 4 mL Collection Instructions: Send specimen refrigerated. Additional Information: Serum is preferred. | 2.0 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative at <1:2 Note: Titers lower than 1:2 are detectable by recombinant CRMP-5 Western blot analysis. CRMP-5 Western blot analysis will be done on request on stored spinal fluid (held 4 weeks). This supplemental testing is recommended in cases of chorea, vision loss, cranial neuropathy, and myelopathy. Call the Neuroimmunology Laboratory at [PHONE] to request CRMP-5 Western blot. | Monday through Friday; 11:30 a.m. | 3 days if negative; 5 days if positive | 8 days | 1 | 86256 |  |  | Yes | No
CRMC | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
CRMC | Result | 21650 | CRMP-5-IgG, CSF | CRMP-5-IgG, CSF | Alphanumeric |  |  |  |  | titer |  |  |  |  |  |  |  |  |  | 35385-4 | [NAME].[NAME]:Titr:Pt:CSF:Qn:
PNEOE | [NAME] | WBNC | [NAME], Western Blot Confirmation, Spinal Fluid | [NAME],CSF | Western Blot | Plastic vial: PlV |  |  | 2 | mL | [NAME]: 2 mL Collection Instructions: Send specimen refrigerated. Additional Information: Serum is preferred. Spinal fluid is particularly useful if interfering antibodies are present. | 1.5 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative (reported as negative or positive) | Monday through Friday; 8 a.m. | 3 days if negative, 5 days if positive | 8 days | 1 | 84182 |  |  | No | No
WBNC | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
WBNC | Result | 21764 | [NAME],CSF | [NAME],CSF | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 53715-9 | Paraneoplastic Ab:ACnc:Pt:CSF:[NAME]:IB
PNEOE | [NAME] | CRMWC | [NAME] Protein-5-IgG (CRMP-5-IgG) Western Blot, [NAME] | CRMP-5-IgG Western Blot, CSF | Western Blot | Plastic vial: PlV |  |  | 3 | mL | [NAME]: 3 mL Collection Instructions: Send specimen refrigerated. Additional Information: 1. Serum is preferred. 2. Include name, phone number, mailing address, and E-mail address (if applicable) of ordering physician. | 2.0 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative (reported as positive or negative) | Tuesday, Thursday; 8 a.m. | 3 days if negative; 5 days if positive | 10 days | 1 | 84182 |  |  | No | No
CRMWC | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
CRMWC | Result | 21747 | CRMP-5-IgG Western Blot, CSF | CRMP-5-IgG Western Blot, CSF | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 53707-6 | [NAME].[NAME]:ACnc:Pt:CSF:[NAME]:IB
PNEOE | [NAME] | GD65C | Glutamic Acid Decarboxylase (GAD65) Antibody Assay, Spinal Fluid | GAD65 Ab Assay, CSF | Immunoprecipitation Assay | Plastic vial: PlV |  |  | 1 | mL | Container/Tube: Sterile vial [NAME]: 1 mL Forms: If not ordering electronically, submit a General Request Form (Supply T239) with the specimen. | 0.75 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | < or =0.02 nmol/L | Monday through Friday;  6 a.m. | 2 days/negative 3 days/positive | 6 days | 1 | 86341 |  |  | No | Yes
GD65C | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
GD65C | Result | 21702 | GAD65 Ab Assay, CSF | GAD65 Ab Assay, CSF | Numeric |  |  |  |  | nmol/L |  |  |  |  |  |  |  |  |  | 53708-4 | Glutamate decarboxylase 65 Ab:SCnc:Pt:CSF:Qn:
PNEOE | [NAME] | ABLTC | Amphiphysin Antibody Western Blot, [NAME] | Amphiphysin Western Blot, CSF | Western Blot |  |  |  |  |  | [NAME]: 1 mL Collection Instructions: Send specimen refrigerated. | 0.75 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm OK; Cold OK Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative | Monday through Friday; On request | 4 days | 10 days | 1 | 84182 |  |  | No | No
ABLTC | [NAME] | CSF | CSF |  |  |  | Refrigerated | 14 days
ABLTC | Result | 89380 | Amphiphysin Western Blot, CSF | Amphiphysin Western Blot, CSF | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 57750-2 | [NAME]:ACnc:Pt:CSF:[NAME]:IB
PNEOE | [NAME] | NMOCC | Neuromyelitis Optica (NMO)/Aquaporin-4-IgG Cell-Binding Assay, CSF | NMO/AQP4-IgG CBA, CSF | Cell-binding assay (CBA) detects IgG specific for [NAME] (M1 isoform) by indirect immunofluorescence (IFA) | Plastic vial: PlV |  |  | 1 | mL | Collection Container/Tube: Sterile vial [NAME]: 1 mL Additional Information: Include relevant clinical information, name, phone number, mailing address, and e-mail address (if applicable) of ordering physician. | 0.5 mL | Hemolysis	Mild OK; Gross reject  Thawing	Warm OK; Cold OK Lipemia	Mild OK; [NAME] OK Icterus	Mild reject; Gross reject Other	NA | Negative | Monday through Friday; 8 a.m. | Negative: 2 days; Positive: 3 days | 6 days | 1 | 86255 |  |  | No | Yes
NMOCC | [NAME] | CSF | CSF |  |  |  | Refrigerated | 28 days
NMOCC | Result | 61716 | NMO/AQP4-IgG CBA, CSF | NMO/AQP4-IgG CBA, CSF | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | In Process