Spreadsheet: 054aafbf-8243-4d91-a67c-6204b6a90099
Sheet: Sheet1

Supplementary Table 9: Probeset associations with known bone-related GWAS loci | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14
GWAS SNP | Chr. location | HOb PS | HOb PV (PS) | LCL PS | LCL PV (PS) | SNP in LD | Chr. location | R2 | D' | HOb PS | HOb PV (PS) | LCL PS | LCL PV (PS) | HOb (PV min)
rs6007594 | 22:44107034 | 3948557 | 0.003525 | 3948596 | 6.301e-06 | rs136564* | 22:44143538 | 0.1 | 1 | 3948557 | 4.884e-07 | 3948570 | 1.18e-11 | 4.884e-07
rs1422795 | 5:156868942 | 2883492 | 0.0002674 | 2883559 | 0.0005241 | rs6899205* | 5:156875863 | 0.7 | 1 | 2883475 | 1.516e-05 | 2883559 | 0.003251 | 1.516e-05
rs6712473 | 2:33267144 | 2476600 | 3.477e-05 | 2476518 | 0.01967 | rs2290449* | 2:33296053 | 0.8 | 1 | 2476594 | 9.13e-05 | 2476658 | 0.05964 | 3.477e-05
rs2238599 | 19:2091009 | 3845711 | 0.002559 | 3845736 | 1.921e-05 | rs3786971* | 19:2092209 | 0.7 | 1 | 3816241 | 0.0001927 | 3845751 | 1.779e-05 | 0.0001927
rs12437971 | 15:98662088 | 3641814 | 0.154 | 3641807 | 0.05318 | rs6598327* | 15:98678070 | 0.1 | 1 | 3641788 | 0.0004753 | 3641666 | 0.001266 | 0.0004753
rs3134295 | 8:104496535 | 3110264 | 0.03708 | 3110264 | 0.02316 | rs3133810* | 8:104484294 | 0.1 | 1 | 3110372 | 0.0003887 | 3110335 | 0.006126 | 0.0003887
rs8100029 | 19:7354832 | 3818944 | 0.007264 | 3818867 | 0.008752 | rs11879985* | 19:7326223 | 0.6 | 1 | 3818893 | 0.0004336 | 3818914 | 0.01474 | 0.0004336
rs12775433* | 10:101824082 | 3260469 | 0.000618 | 3303375 | 0.002667 | rs7906355 | 10:101828257 | 0.8 | 1 | 3303371 | 0.003067 | 3303274 | 0.005184 | 0.000618
rs9328576* | 15:98633466 | 3641792 | 0.001209 | 3641638 | 0.05038 | rs4965623 | 15:98638227 | 0.5 | 1 | 3641792 | 0.002797 | 3641816 | 0.0222 | 0.001209
rs9898793 | 17:40471839 | 3759369 | 0.001774 | 3759566 | 0.0004968 | rs2337437* | 17:40451755 | 0.1 | 1 | 3759384 | 0.001103 | 3759700 | 0.02229 | 0.001103
rs9329383 | 19:7390741 | 3818944 | 0.005885 | 3848485 | 0.001247 | rs4804602* | 19:7393313 | 0.1 | 1 | 3818805 | 0.0005744 | 3818792 | 0.0002951 | 0.0005744
rs10490823 | 3:41098739 | 2670587 | 0.002805 | 2670583 | 0.02355 | rs6788984* | 3:41082177 | 0.3 | 1 | 2670617 | 0.0004596 | 2670613 | 0.08321 | 0.0004596
[NAME] | 9:100035579 | 3217197 | 0.02246 | 3217299 | 0.009096 | rs1573025* | 9:100031251 | 0.7 | 1 | 3217217 | 0.0001481 | 3217199 | 0.02778 | 0.0001481
rs2157839 | 17:40506926 | 3759416 | 0.002844 | 3723189 | 0.0006501 | rs2239920* | 17:40525948 | 0.5 | 1 | 3759416 | 0.0001232 | 3723189 | 0.0002789 | 0.0001232
rs2232965 | 19:18287950 | 3855001 | 0.001848 | 3854874 | 0.006201 | rs12985909* | 19:18300383 | 0.4 | 1 | 3855043 | 0.001585 | 3854966 | 0.009775 | 0.001585
rs227584 | 17:39581073 | 3759142 | 0.003874 | 3722788 | 5.517e-06 | [NAME]* | 17:39628112 | 0.4 | 1 | 3759154 | 0.001892 | 3722801 | 6.018e-05 | 0.001892
rs712219 | 6:152020132 | 2979732 | 0.00851 | 2979720 | 0.03284 | rs851997* | 6:152027243 | 0.4 | 1 | 2979732 | 0.0003446 | 2931734 | 0.04134 | 0.0003446
[NAME] | 3:195543521 | 2658628 | 0.03344 | 2711775 | 0.003465 | rs6763011* | 3:195548028 | 0.2 | 1 | 2711636 | 0.0006199 | 2711691 | 0.008567 | 0.0006199
rs1007738 | 11:46805936 | 3371792 | 0.0002774 | 3329470 | 0.01678 | rs7101374* | 11:46780817 | 1 | 1 | 3371792 | 0.0003505 | 3329470 | 0.01666 | 0.0002774
rs6485702 | 11:46855347 | 3371792 | 0.000899 | 3329470 | 0.003039 | rs1007738* | 11:46805936 | 0.5 | 1 | 3371792 | 0.0002774 | 3329470 | 0.01678 | 0.0002774
rs563811 | 11:107277314 | 3389985 | 0.003746 | 3389987 | 0.001247 | rs10890774* | 11:107267436 | 0.2 | 1 | 3389991 | 0.0005004 | 3389981 | 0.007698 | 0.0005004
rs10164815 | 2:187406128 | 2519288 | 0.006723 | 2591302 | 0.03434 | rs3114949* | 2:187413111 | 0.2 | 1 | 2519312 | 0.001001 | 2591301 | 0.0061 | 0.001001
rs2666472 | 1:62501372 | 2415950 | 0.004136 | 2415948 | 0.001182 | rs12062559* | 1:62497341 | 0.1 | 1 | 2339430 | 0.002298 | 2415859 | 0.004084 | 0.002298
rs7751941 | 6:151988351 | 2979682 | 0.00987 | 2931714 | 0.005217 | rs6929137* | 6:151978370 | 0.7 | 1 | 2931702 | 0.003093 | 2931714 | 0.01361 | 0.003093
rs6929137* | 6:151978370 | 2931702 | 0.003093 | 2931714 | 0.01361 | rs3734806 | 6:151983154 | 1 | 1 | 2931702 | 0.003336 | 2931714 | 0.01142 | 0.003093
rs6908735 | 6:70953236 | 2960180 | 0.004581 | 2960171 | 0.03358 | rs802173* | 6:70931955 | 0.4 | 1 | 2912828 | 0.001575 | 2912708 | 0.01351 | 0.001575
rs6769400 | 3:36933999 | 2669202 | 0.002812 | 2669257 | 0.09637 | rs7622114* | 3:36935664 | 0.5 | 1 | 2669259 | 0.00109 | 2616986 | 0.01893 | 0.00109
rs5910713 | [NAME] | 4019633 | 0.03604 | 3989066 | 0.01409 | rs7063278* | X:119000782 | 0.5 | 1 | 4019633 | 0.002489 | 3989072 | 0.02304 | 0.002489
rs2010281 | 14:102932075 | 3553838 | 0.03802 | 3580770 | 0.002471 | rs2065015* | 14:102973814 | 0.4 | 1 | 3553694 | 0.008077 | 3553835 | 0.00111 | 0.008077
rs10984103 | 9:99679096 | 3181320 | 0.01822 | 3217182 | 0.03796 | rs10512256* | 9:99726636 | 0.3 | 1 | 3181466 | 0.002912 | 3217174 | 0.01795 | 0.002912
rs3730071 | 12:47455065 | 3413703 | 0.02742 | 3413530 | 0.0007837 | rs10783284* | 12:47438303 | 0.1 | 1 | 3453176 | 0.004502 | 3413508 | 0.007549 | 0.004502
rs12767483 | 10:128986846 | 3269943 | 0.06157 | 3269977 | 0.01655 | rs2766034* | 10:128992767 | 0.1 | 1 | 3269943 | 0.001269 | 3269991 | 0.04845 | 0.001269
rs6696981 | 1:22575445 | 2324840 | 0.05837 | 2401019 | 0.02499 | [NAME]* | 1:22588073 | 0.1 | 1 | 2324850 | 0.002757 | 2324843 | 0.01833 | 0.002757
rs2788478 | 7:158365380 | 3034471 | 0.000102 | 3034511 | 0.0001637 | rs12672574 | 7:158376913 | 0.2 | 1 | 3034484 | 0.001484 | 3034494 | 0.007996 | 0.000102
rs9934109 | 16:70037740 | 3697685 | 0.02866 | 3697642 | 0.006877 | rs732318* | 16:70037393 | 0.1 | 1 | 3667656 | 0.02897 | 3697486 | 0.006876 | 0.02866
rs1513670 | 17:39162857 | 3722682 | 0.004613 | 3758767 | 0.003474 | rs9303537* | 17:39169534 | 1 | 1 | 3722682 | 0.004613 | 3758767 | 0.003474 | 0.004613
rs851993 | 6:152047704 | 2931701 | 0.001742 | 2979720 | 0.004893 | rs851995* | 6:152047227 | 0.7 | 1 | 2931692 | 0.00249 | 2931862 | 0.01927 | 0.001742
rs1938595* | 11:58737388 | 3331839 | 0.002402 | 3331853 | 0.0002067 | rs4938914 | 11:58779244 | 0.1 | 1 | 3332005 | 0.00468 | 3331830 | 0.0323 | 0.002402
rs7023773* | 9:119219407 | 3222599 | 0.00225 | 3222614 | 0.02803 | rs7032028 | 9:119198404 | 0.4 | 1 | 3222599 | 0.03985 | 3222730 | 0.003226 | 0.00225
rs7676236 | 4:102793390 | 2737656 | 0.5841 | 2737655 | 0.0005847 | rs7700191* | 4:102808306 | 0.3 | 1 | 2737670 | 0.02686 | 2737621 | 0.08165 | 0.02686
rs4737736 | 8:55926327 | 3098596 | 0.05895 | 3098597 | 0.1982 | rs10095485* | 8:55908161 | 0.9 | 1 | 3098596 | 0.01331 | 3098597 | 0.1914 | 0.01331
rs1943638 | 11:56299394 | 3331049 | 0.001393 | 3373521 | 0.07475 | rs1788998* | 11:56344551 | 0.1 | 1 | 3373504 | 0.008476 | 3373488 | 0.08049 | 0.001393
rs9298511* | 8:55910956 | 3098596 | 0.01353 | 3098597 | 0.1988 | rs4737736 | 8:55926327 | 0.9 | 1 | 3098596 | 0.05895 | 3098597 | 0.1982 | 0.01353
rs209956 | 20:52156263 | 3910431 | 0.01195 | 3910393 | 0.02664 | rs158534* | 20:52149424 | 0.2 | 1 | 3910431 | 0.007376 | 3910440 | 0.01438 | 0.007376
rs3118912 | 13:50009465 | 3514311 | 0.05822 | 3514312 | 0.0932 | rs3116605* | 13:50015563 | 1 | 1 | 3514311 | 0.008332 | 3514312 | 0.0932 | 0.008332
rs3116605* | 13:50015563 | 3514311 | 0.008332 | 3514312 | 0.0932 | rs1149826 | 13:50028932 | 0.2 | 1 | 3489709 | 0.003551 | 3489711 | 0.04853 | 0.003551
rs6434197 | 2:187406952 | 2519252 | 0.01312 | 2591302 | 0.03434 | [NAME]* | 2:187406128 | 1 | 1 | 2519288 | 0.006723 | 2591302 | 0.03434 | 0.006723
rs10497621 | 2:183705688 | 2590803 | 0.01715 | 2518731 | 0.009923 | rs3748884* | 2:183732435 | 0.1 | 1 | 2518770 | 0.002482 | 2590749 | 0.01353 | 0.002482
rs3118916 | 13:50034809 | 3514311 | 0.05367 | 3514312 | 0.05098 | rs1239687* | 13:50061562 | 0.3 | 1 | 3514323 | 0.0006537 | 3514311 | 0.06345 | 0.0006537
rs4870044* | 6:151943102 | 2979720 | 0.004695 | 2931839 | 0.01569 | rs13213582 | 6:151915589 | 0.3 | 1 | 2931807 | 0.0137 | 2931687 | 0.0002509 | 0.004695
rs450615 | 3:41108614 | 2670587 | 0.003893 | 2670583 | 0.02355 | rs10490823* | 3:41098739 | 1 | 1 | 2670587 | 0.002805 | 2670583 | 0.02355 | 0.002805
rs7310081* | 12:128631682 | 3478124 | 0.001721 | 3478070 | 0.001542 | [NAME] | 12:128628185 | 0.6 | 1 | 3478124 | 0.01594 | 3478070 | 0.006797 | 0.001721
[NAME]* | 6:151995820 | 2931702 | 0.01074 | 2931713 | 0.00747 | rs11757393 | 6:151988211 | 0.4 | 1 | 2931860 | 0.005307 | 2931879 | 0.02421 | 0.005307
rs7753676 | 6:151918508 | 2931718 | 0.1574 | 2931784 | 0.001817 | rs4869738* | 6:151933844 | 0.3 | 1 | 2931718 | 0.01635 | 2931798 | 0.00851 | 0.01635
rs1054627 | 4:88951716 | 2735076 | 0.02119 | 2735265 | 0.001732 | rs1381965* | 4:88947928 | 0.1 | 1 | 2735224 | 0.005608 | 2735082 | 0.0002983 | 0.005608
rs12526857 | 6:143099240 | 2928490 | 0.01011 | 2928539 | 0.02847 | rs197490* | 6:143104496 | 0.1 | 1 | 2977294 | 0.0216 | 2977291 | 0.02855 | 0.01011
rs1159327 | 6:152089715 | 2931702 | 0.0235 | 2931737 | 0.01208 | rs12195741* | 6:152096067 | 0.2 | 1 | 2931711 | 0.007263 | 2931737 | 0.004919 | 0.007263
rs7220711* | 17:39145491 | 3758693 | 0.003198 | 3758767 | 0.002039 | rs4793017 | 17:39136506 | 1 | 1 | 3758693 | 0.003282 | 3758767 | 0.002039 | 0.003198
[NAME] | 18:44710128 | 3787680 | 0.1385 | 3787691 | 0.1225 | rs12953717* | 18:44707927 | 0.1 | 1 | 3807466 | 0.007099 | 3787688 | 0.02967 | 0.007099
rs1038304* | 6:151974868 | 2931701 | 0.003129 | 2931839 | 0.02524 | rs9397433 | 6:151961125 | 0.2 | 1 | 2931839 | 0.01322 | 2931861 | 0.004316 | 0.003129
rs2302677 | 16:52240450 | 3661100 | 0.03969 | 3661107 | 0.02059 | rs1077352* | 16:52222838 | 0.1 | 1 | 3661099 | 0.01383 | 3661111 | 0.01733 | 0.01383
rs6568489 | 6:108145842 | 2968065 | 0.01025 | 2968074 | 0.01625 | rs1728127* | 6:108141100 | 0.5 | 1 | 2968065 | 0.008349 | 2968076 | 0.04054 | 0.008349
rs6468651 | 8:88178848 | 3106018 | 0.1393 | 3106020 | 0.1799 | [NAME]* | 8:88190816 | 0.3 | 1 | 3105992 | 0.0044 | 3106018 | 0.02225 | 0.0044
rs2710057 | X:86078659 | 3983234 | 0.1217 | 3983266 | 0.008105 | rs5967770* | X:86080644 | 0.2 | 1 | 3983264 | 0.00947 | 3983266 | 0.03105 | 0.00947
rs289061 | 12:64964082 | 3420503 | 0.05718 | 3420506 | 0.01605 | rs1816562* | 12:64964604 | 0.3 | 1 | 3420523 | 0.01186 | 3420523 | 0.0001169 | 0.01186
rs12652098 | 5:126219450 | 2827178 | 0.1226 | 2827204 | 0.01151 | rs3805739* | 5:126194090 | 0.2 | 1 | 2827165 | 0.005546 | 2827179 | 0.1758 | 0.005546
rs3783394 | 14:102928426 | 3553838 | 0.03802 | 3580770 | 0.002471 | rs2010281* | 14:102932075 | 1 | 1 | 3553838 | 0.03802 | 3580770 | 0.002471 | 0.03802
rs2451255 | 6:159430804 | 2982083 | 0.02335 | 2982080 | 0.07633 | rs9295089* | 6:159383952 | 0.1 | 1 | 2982090 | 0.0148 | 2982105 | 0.005531 | 0.0148
rs3732477* | 3:195544214 | 2658628 | 0.01513 | 2711775 | 0.003465 | [NAME] | 3:195543521 | 1 | 1 | 2658628 | 0.03344 | 2711775 | 0.003465 | 0.01513
rs5951426* | X:22201527 | 3971473 | 0.01287 | 3971520 | 0.001881 | rs5951739 | X:22176811 | 0.1 | 1 | 3971427 | 0.07688 | 3971520 | 0.02199 | 0.01287
rs1549273 | 5:101576599 | 2869131 | 0.01104 | 2869136 | 0.02531 | [NAME]* | 5:101579566 | 0.1 | 1 | 2869103 | 0.02676 | 2869142 | 0.08822 | 0.01104
rs851982* | 6:152066678 | 2931850 | 0.04645 | 2931734 | 0.01815 | rs851980 | 6:152069648 | 0.4 | 1 | 2931689 | 0.01122 | 2931699 | 0.02532 | 0.01122
rs7024345 | 9:99635059 | 3216963 | 0.0143 | 3216953 | 0.0146 | rs10818094* | 9:99603649 | 0.2 | 1 | 3216972 | 0.007344 | 3216953 | 0.009082 | 0.007344
rs6505558 | 18:10445680 | 3778777 | 0.1089 | 3778775 | 0.05072 | rs8095782* | 18:10437547 | 0.1 | 1 | 3778777 | 0.03275 | 3778840 | 0.01222 | 0.03275
rs2213468 | X:86099449 | 3983304 | 0.04645 | 3983266 | 0.0001186 | rs2710058* | X:86117818 | 0.4 | 1 | 3983304 | 0.0009656 | 3983305 | 0.00128 | 0.0009656
rs10137819* | 14:100464694 | 3552095 | 0.02393 | 3552086 | 0.292 | rs2400963 | 14:100465459 | 0.3 | 1 | 3552347 | 0.01561 | 3552346 | 0.08407 | 0.01561
rs1443434 | 9:99657300 | 3181320 | 0.02082 | 3216953 | 0.06377 | rs10984103* | 9:99679096 | 0.9 | 1 | 3181320 | 0.01822 | 3217182 | 0.03796 | 0.01822
rs7720865 | 5:170918445 | 2840812 | 0.009008 | 2840629 | 0.005747 | rs1030676* | 5:170931675 | 0.2 | 1 | 2840812 | 0.007411 | 2840790 | 0.08049 | 0.007411
rs524410 | 6:159418118 | 2982083 | 0.0164 | 2982080 | 0.05217 | rs2451255* | 6:159430804 | 0.9 | 1 | 2982083 | 0.02335 | 2982080 | 0.07633 | 0.0164
rs1547960 | 7:120732453 | 3021159 | 0.02881 | 3021270 | 0.01003 | rs2707521* | 7:120727672 | 1 | 1 | 3021159 | 0.03084 | 3021270 | 0.01904 | 0.02881
rs6796430 | 3:73950170 | 2682750 | 0.119 | 2682844 | 0.00295 | rs17028298* | 3:73950555 | 0.2 | 1 | 2682750 | 0.06395 | 2682750 | 0.009863 | 0.06395
rs2037957 | 8:134528403 | 3116845 | 0.07693 | 3154413 | 0.2124 | rs13274799* | 8:134523561 | 0.4 | 1 | 3116847 | 0.04013 | 3116842 | 0.006917 | 0.04013
[NAME] | 4:30973757 | 2722839 | 0.09682 | 2722847 | 0.1639 | rs6854032* | 4:30976308 | 0.1 | 1 | 2722885 | 0.01942 | 2722847 | 0.06597 | 0.01942
rs921416 | 1:103001167 | 2425823 | 0.0923 | 2425839 | 0.001334 | rs12074523* | 1:103040347 | 0.3 | 1 | 2425823 | 0.03629 | 2425826 | 0.002755 | 0.03629
rs1219395 | 11:121267606 | 3353041 | 0.1224 | 3353033 | 0.06945 | rs1219396* | 11:121265814 | 0.3 | 1 | 3352989 | 0.1004 | 3352949 | 0.07053 | 0.1004
rs405717 | 4:104691520 | 2780299 | 0.0647 | 2780310 | 0.02104 | rs2588907* | 4:104712819 | 0.7 | 1 | 2780299 | 0.05313 | 2780310 | 0.02501 | 0.05313
rs10003871 | 4:142479872 | 2745253 | 0.1796 | 2745231 | 0.2611 | rs4267812* | 4:142518152 | 0.2 | 1 | 2745231 | 0.05216 | 2745245 | 0.07217 | 0.05216
rs4507007* | 18:57537499 | 3791019 | 0.03161 | 3791002 | 0.07701 | rs6567237 | 18:57523076 | 0.1 | 1 | 3791025 | 0.07535 | 3791022 | 0.1328 | 0.03161
rs7521528 | 1:163004212 | 2364688 | 0.0355 | 2364799 | 0.04006 | [NAME]* | 1:163004173 | 1 | 1 | 2364688 | 0.0355 | 2364799 | 0.02591 | 0.0355
[NAME] | 1:163004173 | 2364688 | 0.0355 | 2364799 | 0.02591 | rs7521528* | 1:163004212 | 1 | 1 | 2364688 | 0.0355 | 2364799 | 0.04006 | 0.0355
rs6825793 | 4:142454943 | 2745249 | 0.4953 | 2745231 | 0.1157 | rs17456275* | 4:142492540 | 0.6 | 1 | 2745240 | 0.06952 | 2745231 | 0.01394 | 0.06952
rs5019445 | 4:182363116 |  |  |  |  | rs10003686 | 4:182359196 | 0.4 | 1
rs11719399 | 3:118798496 |  |  |  |  | rs10511370 | 3:118808667 | 0.2 | 1
rs7645105 | 3:118808141 |  |  |  |  | rs11719399 | 3:118798496 | 1 | 1
rs9375195 | 6:98669441 |  |  |  |  | rs1386550 | 6:98659256 | 0.2 | 1
rs1933720 | 6:98404553 |  |  |  |  | rs4142529 | 6:98429082 | 0.1 | 1
rs6735786 | 2:103136670 |  |  |  |  | rs4319952 | 2:103140257 | 0.2 | 1
rs4075039 | 3:118645474 |  |  |  |  | rs9881096 | 3:118641140 | 0.4 | 1
* SNP with the most significant p value for the probeset association