Spreadsheet: e74737a6-5391-4144-b0ed-f3e6bd6f5956
Sheet: Sheet1

Protein name | Publications on subcellular localization and protein-protein interactions | Unnamed: 2
Add1 | Zhang, M., Kalinec, G.M., Urrutia, R., Billadeau, D.D. and Kalinec, F. (2003). ROCK-dependent and ROCK-independent control of cochlear outer hair cell electromotility. [NAME]. Chem. 278, 35644-35650.
 | [NAME], [NAME] and [NAME], V. (1996). Identification of the spectrin subunit and domains required for formation of spectrin/adducin/actin complexes. [NAME]. Chem. 271, 15695-15702.
Ap1s2 | [NAME], M.S. (2004). Adaptable adaptors for coated vesicles. [NAME]. 14, 167-174.
Atl2 | Rismanchi, N., Soderblom, C., [NAME], [NAME], Zhu, P.P. and Blackstone, C. (2008). [NAME] are required for Golgi apparatus and ER morphogenesis. Hum. [NAME]. [NAME]. 17, 1591-1604.
C230096C10Rik (a homolog of the yeast protein Emc1p) | Jonikas, M.C., Collins, S.R., Denic, V., Oh, E., Quan, E.M., Schmid, V., Weibezahn, J., Schwappach, B., [NAME], P., Weissman, J.S. et al. (2009). Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323, 1693-1697.
Cacna1b | [NAME], [NAME], Südhof, T.C. and Bezprozvanny, I. (1999). Association of neuronal calcium channels with modular adaptor proteins. [NAME]. Chem. 274, 24453-24456.
 | Waithe, D., Ferron, L., Page, K.M., Chaggar, K. and Dolphin, A.C. (2011). Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation. [NAME]. Chem. 286, 9598-9611.
Cacna1d | Neef, J., Gehrt, A., Bulankina, [NAME], Meyer, A.C., Riedel, D., [NAME], R.G., Strenzke, N. and Moser, [NAME] (2009). The Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearing. [NAME]. 29, 10730-10740.
 | Kaeser, P.S., [NAME], [NAME] , [NAME], [NAME], [NAME], [NAME], [NAME], [NAME], [NAME], [NAME] and Südhof, T.C. (2011). RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interaction. Cell 144, 282-295.
Cacnb1 | Buraei, [NAME] and [NAME], J. (2010). The ß subunit of voltage-gated Ca2+ channels. Physiol. Rev. 90, 1461-1506.
 | Waithe, D., Ferron, L., Page, K.M., Chaggar, K. and Dolphin, A.C. (2011). Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation. [NAME]. Chem. 286, 9598-9611.
Cacnb2 | Neef, J., Gehrt, A., Bulankina, [NAME], Meyer, A.C., Riedel, D., [NAME], R.G., Strenzke, N. and Moser, [NAME] (2009). The Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearing. [NAME]. 29, 10730-10740.
 | Kiyonaka, S., Wakamori, M., [NAME], [NAME], [NAME], [NAME], Nonaka, M., Bito, H., Beedle, A.M., [NAME], E., [NAME], [NAME], De Waard, M. et al. (2007). RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels. Nat. Neurosci. 10, 691-701.
Cadps (a.k.a. Caps) | Daily, N.J., Boswell, K.L., [NAME], D.J. and Martin, T.F. (2010). Novel interactions of CAPS (Ca2+-dependent activator protein for secretion) with the three neuronal SNARE proteins required for vesicle fusion. [NAME]. Chem. 285, 35320-35329.
 | Sadakata, T., [NAME], [NAME], [NAME], [NAME], Saruta, C., Itakura, M., Takahashi, M. and Furuichi, T. (2010). Interaction of calcium-dependent activator protein for secretion 1 (CAPS1) with the class II ADP-ribosylation factor small GTPases is required for dense-core vesicle trafficking in the trans-Golgi network. [NAME]. Chem. 285, 38710-38719.
 | Jockusch, W.J., Speidel, D., [NAME], [NAME], Sørensen, J.B., Varoqueaux, F., Rhee, J.S. and [NAME], [NAME] (2007). [NAME] and CAPS-2 are essential synaptic vesicle priming proteins. Cell 131, 796-808.
Cask | [NAME], [NAME] and Garner, C.C. (2008). Molecular mechanisms of presynaptic differentiation. Annu. Rev. [NAME]. Biol. 24, 237-262.
 | Olsen, O., Moore, K.A., Nicoll, R.A. and Bredt, D.S. (2006). Synaptic transmission regulated by a presynaptic MALS/Liprin-alpha protein complex. Curr. Opin. Cell Biol. 18, 223-227.
 | Hata, Y., [NAME], S. and Südhof, T.C. (1996). CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins. [NAME]. 16, 2488-2494.
 | Butz, S., Okamoto, M. and Südhof, T.C. (1998). A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Cell 94, 773-782.
Dopey1 (a homolog of the yeast protein Dop1) | Gillingham, A.K., Whyte, J.R., Panic, [NAME] and [NAME], [NAME] (2006). Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus. [NAME]. Chem. 281, 2273-2280.
Dtna | [NAME], C.F., Vlachouli, C., Blake, D.J., Simons, J.P. and Górecki, D.C. (2004). Differential spatio-temporal expression of alpha-dystrobrevin-1 during mouse development. [NAME]. Patterns. 4, 583-593.
Dync1ic2 | [NAME], J.R. and Vale, R.D. (2009). Regulators of the cytoplasmic dynein motor. [NAME]. Rev. [NAME]. Cell Biol. 10, 854-865.
Erc2 (a.k.a. Cast1) | Hida, [NAME] and Ohtsuka, T. (2010). CAST and ELKS proteins: structural and functional determinants of the presynaptic active zone. [NAME]. 148, 131-137.
 | Schoch, S. and Gundelfinger, E.D. (2006). Molecular organization of the presynaptic active zone. Cell [NAME]. 326, 370-391.
Ergic3 | Nishikawa, M., [NAME], [NAME], Yabunaka, [NAME] and Inoue, M. (2006). Identification and characterization of endoplasmic reticulum-associated protein, ERp43. [NAME], 42-51.
Fkbp1b | Timerman, A.P., Onoue, H., Xin, H.B., Barg, S., Copello, J., [NAME], [NAME] and [NAME], [NAME] (1996). Selective binding of FKBP12.6 by the cardiac ryanodine receptor. [NAME]. Chem. 271, 20385-20391.
 | Morton-Jones, R.T., Cannell, M.B., Jeyakumar, L.H., [NAME], S. and Housley, G.D. (2005). Differential expression of ryanodine receptors in the rat cochlea. Neuroscience 137, 275-286.
 | Zalk, R, Lehnart, [NAME] and Marks, A.R. (2007). Modulation of the ryanodine receptor and intracellular calcium. Annu. Rev. [NAME]. 76, 367-385.
Kcnq2 | [NAME], Z, Liang, G.H., Cooper, E.C. and Jarlebark, [NAME] (2009). Expression and localization of K channels KCNQ2 and KCNQ3 in the mammalian cochlea. [NAME]. [NAME]. 14, 98-105.
 | [NAME], [NAME], Degani-Katzav, N, ., [NAME], A., Etzioni, A., Siloni, S., Alaimo, A., Chikvashvili, D., Villarroel, [NAME], Attali, B. and Lotan, I. (2009). Selective interaction of syntaxin 1A with KCNQ2: possible implications for specific modulation of presynaptic activity. [NAME] One 4, e6586.
Kif1b | Hirokawa, N., Noda, Y., [NAME], [NAME] and Niwa, S. (2009). [NAME] superfamily motor proteins and intracellular transport. [NAME]. Rev. [NAME]. Cell Biol. 10, 682-696.
Lmo7 | Ooshio, T., Irie, K., Morimoto, K., Fukuhara, A., [NAME], [NAME] and Takai, [NAME] (2004). Involvement of LMO7 in the association of two cell-cell adhesion molecules, [NAME] E-cadherin, through afadin and alpha-actinin in epithelial cells. [NAME]. Chem. 279, 31365-31373.
 | Takai, Y., Ikeda, W., Ogita, H. and Rikitake, [NAME] (2008). The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin. Annu. Rev. [NAME]. Biol. 24, 309-342.
Madd | Yamaguchi, K., [NAME], M., Mizoguchi, A., Hirata, Y., Ishizaki, [NAME], Kaneko, K., Miyoshi, [NAME] and Takai, [NAME] (2002). A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. Proc. Natl. Acad. [NAME]. U. S. A. 99, 14536-14541.
 | [NAME], M., Miyoshi, J., Ishizaki, H., Togawa, A., Ohnishi, K., Endo, K., Matsubara, K., Mizoguchi, A., Nagano, T., Sato, M. et al. (2001). Role of [NAME] GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction. [NAME]. [NAME]. 12, 1421-1430.
 | Hirokawa, N., Noda, Y., [NAME], [NAME] and Niwa, S. (2009). [NAME] superfamily motor proteins and intracellular transport. [NAME]. Rev. [NAME]. Cell Biol. 10, 682-696.
Mcf2l (a.k.a Dbs, [NAME]) | Ieguchi, K., Ueda, S., Kataoka, T. and Satoh, [NAME] (2007). Role of the guanine nucleotide exchange factor [NAME] in negative regulation of receptor endocytosis by the small GTPase Rac1. [NAME]. Chem. 282, 23296-23305.
Mef2d | Flavell, S.W., Cowan, C.W., Greer, P.L., [NAME], [NAME], Paradis, S., Griffith, E.C., [NAME], L.S., [NAME], C. and Greenberg, M.E. (2006). Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science 311, 1008-1012.
 | Flavell, S.W., [NAME], T.K., Gray, J.M., Harmin, D.A., Hemberg, M., Hong, E.J., Markenscoff-Papadimitriou, E., Bear, D.M. and Greenberg, M.E. (2008). Genome-wide analysis of MEF2 transcriptional program reveals synaptic target genes and neuronal activity-dependent polyadenylation site selection. Neuron 60, 1022-1038.
Mpp7 | Bohl, J., Brimer, N., Lyons, C. and Vande Pol, S.B. (2007). The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions. [NAME]. Chem. 282, 9392-9400.
Nrcam | Grumet, M. (1997). Nr-CAM: a cell adhesion molecule with ligand and receptor functions. Cell [NAME]. 290, 423-428.
 | [NAME], J.Q. and [NAME], V. (1994). Ankyrin binding activity shared by the neurofascin/L1/NrCAM family of nervous system cell adhesion molecules. [NAME]. Chem. 269, 27163-27166.
Nrxn3 | Lisé, M.F. and El-Husseini, A. (2006). The neuroligin and neurexin families: from structure to function at the synapse. Cell Mol. Life Sci. 63, 1833-1849.
 | [NAME], [NAME] and [NAME], [NAME] (2007). Neurexin-neuroligin signaling in synapse development. Curr. Opin. [NAME]. 17, 43-52.
Phf21a/Bhc80 | [NAME], A., Ferrai, C., Stucchi, L., Prada, I., Podini, P., Baba, T., Rocchi, M., Meldolesi, [NAME] and [NAME], R. (2009). The rest repression of the neurosecretory phenotype is negatively modulated by BHC80, a protein of the BRAF/HDAC complex. [NAME]. 29, 6296-6307.
 | Iwase, S., Januma, A., Miyamoto, K., Shono, N., Honda, [NAME], Yanagisawa, [NAME] and Baba, T. (2004). Characterization of BHC80 in BRAF-HDAC complex, involved in neuron-specific gene repression. Biochem. Biophys. [NAME]. [NAME]. 322, 601-608.
Ppp3cb (a.k.a. calcineurin A beta) | Lopez, E., Rosado, J.A. and Redondo, P.C. (2011). Immunophilins and thrombotic disorders. Curr. Med. Chem. 18, 5414-5423.
 | Bultynck, [NAME], [NAME], E., Szlufcik, K., De Smet, P., Fissore, R.A., [NAME], [NAME], [NAME], [NAME], De Smedt, H. and Parys, J.B. (2003). Calcineurin and intracellular Ca2+-release channels: regulation or association? Biochem. Biophys. [NAME]. [NAME]. 311, 1181-1193.
[NAME] | Serra-Pagès, C., Medley, Q.G., [NAME], M., Hart, [NAME] and [NAME], M. (1998). [NAME], a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. [NAME]. Chem. 273, 15611-15620.
 | [NAME], J., Na, M., [NAME], S., Lee, [NAME] and [NAME], E. (2003). Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins. [NAME]. Chem. 278, 42377-42385.
Rapgef6 (a.k.a. PDZgef2) | Kuiperij, H.B., de Rooij, [NAME], [NAME], [NAME], [NAME], M., Wittinghofer, A., [NAME], J.L. and Zwartkruis, F.J. (2003). Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2. [NAME]. Biophys. [NAME]. 1593, 141-149.
 | Pannekoek, W.J., Kooistra, M.R., Zwartkruis, F.J. and Bos, J.L. (2009). Cell-cell junction formation: the role of Rap1 and Rap1 guanine nucleotide exchange factors. [NAME]. Biophys. [NAME]. 1788, 790-796.
 | Severson, E.A., Lee, W.Y., Capaldo, C.T., Nusrat, [NAME] and [NAME], C.A. (2009). Junctional adhesion molecule A interacts with [NAME] and PDZ-GEF2 to activate Rap1A, regulate [NAME] integrin levels, and enhance cell migration. [NAME]. Biol. Cell 20, 1916-1925.
 | Boettner, B., Govek, E.E., Cross, [NAME] and [NAME], [NAME] (2000). The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proc. Natl. Acad. [NAME]. U. S. A. 97, 9064-9069.
Rest (a.k.a. Nrsf) | Ooi, L. and Wood, I.C. (2007). Chromatin crosstalk in development and disease: lessons from REST. [NAME]. Rev. [NAME]. 8, 544-554.
Rims2 | Schoch, S. and Gundelfinger, E.D. (2006). Molecular organization of the presynaptic active zone. Cell [NAME]. 326, 370-391.
 | Olsen, O., Moore, K.A., Nicoll, R.A. and Bredt, D.S. (2006). Synaptic transmission regulated by a presynaptic MALS/Liprin-alpha protein complex. Curr. Opin. Cell Biol. 18, 223-227.
Sgip1 | Uezu, A., Horiuchi, A., Kanda, K., Kikuchi, N., Umeda, K., Tsujita, K., Suetsugu, S., Araki, [NAME], Yamamoto, H., Takenawa, [NAME] (2007). SGIP1alpha is an endocytic protein that directly interacts with phospholipids and Eps15. [NAME]. Chem. 282, 26481-26489.
Sh3glb1 | Cheung, Z.H. and Ip, N.Y. (2009). Endophilin B1: Guarding the gate to destruction. [NAME]. Integr. Biol. 2, 130-132.
 | Lee, S.Y., Wenk, M.R., [NAME], [NAME], Nairn, A.C. and [NAME], P. (2004). Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses. Proc. Natl. Acad. [NAME]. [NAME], 546-551.
Snap91 | Morgan, [NAME], Prasad, K., [NAME], S., [NAME], G.J. and Lafer, [NAME] (2003). Eps15 homology domain-NPF motif interactions regulate clathrin coat assembly during synaptic vesicle recycling. [NAME]. Chem. 278, 33583-33592.
 | [NAME], F., Mattson, [NAME] and [NAME], [NAME] (2010). Neuronal activity and the expression of clathrin-assembly protein AP180. Biochem. Biophys. [NAME]. [NAME]. 402, 297-300.
 | Yao, P.J., Petralia, R.S., Bushlin, I., Wang, [NAME] and Furukawa, K. (2005). Synaptic distribution of the endocytic accessory proteins AP180 and CALM. [NAME]. Neurol. 481, 58-69.
Snx14 | Worby, C.A. and [NAME], [NAME] (2002). Sorting out the cellular functions of sorting nexins. [NAME]. Rev. [NAME]. Cell Biol. 3, 919-931.
Synj1 | Haffner, C., Takei, K., [NAME], H., Ringstad, [NAME], Hudson, A., Butler, M.H., Salcini, A.E., Di Fiore, P.P. and [NAME], P. (1997). Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15. [NAME]. 419, 175-180.
 | Slepnev, V.I. and De Camilli, P. (2000). Accessory factors in clathrin-dependent synaptic vesicle endocytosis. Nat. Rev. [NAME]. 1, 161-172.
 | Song, [NAME] and Zinsmaier, [NAME] (2003). Endophilin and synaptojanin hook up to promote synaptic vesicle endocytosis. [NAME], 665-667.
Vps13c | Velayos-Baeza, [NAME], Levecque, C., Dobson-Stone, C. and Monaco, A.P. (2008). The Function of Chorein. Neuroacanthocytosis Syndromes II., .
 | Velayos-Baeza, A., Vettori, A., Copley, R.R., Dobson-Stone, C. and Monaco, A.P. (2004). Analysis of the human VPS13 gene family. Genomics 84, 536-549.
Wdr35 | Gilissen, C., Arts, H.H., [NAME], A., Spruijt, L., Mans, D.A., Arts, P., [NAME], [NAME], Steehouwer, M., [NAME], J., Kant, [NAME] et al. (2010). Exome sequencing identifies WDR35 variants involved in [NAME] syndrome. Am. [NAME]. [NAME]. 87, 418-423.