Spreadsheet: fdd07cc7-5968-424c-bc39-3b1424515ef4
Sheet: Table S6

Biological Process in human PSD as compared with human genome |  |  |  |  |  |  |  | Biological Process in mouse PSD as compared with human genome
Biological Process | Homo sapiens genes | Observed | Expected | (over/under) | P-value | Corrected P-value |  | Biological Process | Observed | Expected | (over/under) | P-value | Corrected P-value
Unclassified | 7108 | 25 | 61.05 | - | 6.38e-10 | 1.35894e-07 |  | neurological system process | 49 | 15.72 | + | 1.62e-12 | 2.92875e-10
protein folding | 197 | 14 | 1.69 | + | 2.45e-09 | 2.60925e-07 |  | synaptic transmission | 30 | 6.29 | + | 2.75e-12 | 2.92875e-10
transcription | 1993 | 1 | 17.12 | - | 2.94e-07 | 1.47822e-05 |  | system process | 52 | 19.19 | + | 5.21e-11 | 3.6991e-09
transcription from RNA polymerase II promoter | 1987 | 1 | 17.06 | - | 3.11e-07 | 1.47822e-05 |  | cell communication | 94 | 49.42 | + | 9.05e-11 | 4.819125e-09
protein transport | 1254 | 30 | 10.77 | + | 3.47e-07 | 1.47822e-05 |  | nerve-nerve synaptic transmission | 13 | 1.14 | + | 2.49e-10 | 1.06074e-08
intracellular protein transport | 1254 | 30 | 10.77 | + | 3.47e-07 | 1.47822e-05 |  | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 12 | 44.87 | - | 6.11e-10 | 2.16905e-08
regulation of transcription from RNA polymerase II promoter | 1563 | 0 | 13.42 | - | 8.49e-07 | 2.583385714285714e-05 |  | cellular process | 118 | 72.49 | + | 1.96e-09 | 5.964e-08
cellular component morphogenesis | 734 | 19 | 6.3 | + | 2.1e-05 | 0.00046434 |  | regulation of transcription from RNA polymerase II promoter | 1 | 21.27 | - | 5.76e-09 | 1.5336e-07
anatomical structure morphogenesis | 734 | 19 | 6.3 | + | 2.1e-05 | 0.00046434 |  | transport | 64 | 32.24 | + | 5.9e-08 | 1.396333333333333e-06
response to stress | 265 | 11 | 2.28 | + | 2.18e-05 | 0.00046434 |  | cell-cell signaling | 32 | 11.73 | + | 3.53e-07 | 7.5189e-06
[NAME] process | 2803 | 44 | 24.07 | + | 4.15e-05 | 0.0008035909090909091 |  | transcription | 6 | 27.13 | - | 4.73e-07 | 9.017e-06
vesicle-mediated transport | 801 | 19 | 6.88 | + | 6.74e-05 | 0.00119635 |  | transcription from RNA polymerase II promoter | 6 | 27.04 | - | 5.08e-07 | 9.017e-06
cellular component organization | 989 | 20 | 8.49 | + | 0.000355 | 0.005816538461538462 |  | signal transduction | 80 | 46.97 | + | 5.55e-07 | 9.093461538461538e-06
protein complex assembly | 73 | 5 | 0.63 | + | 0.00046 | 0.006588800000000001 |  | vesicle-mediated transport | 29 | 10.9 | + | 2.12e-06 | 3.225428571428571e-05
transport | 2369 | 36 | 20.35 | + | 0.000464 | 0.006588800000000001 |  | protein transport | 36 | 17.07 | + | 2.12e-05 | 0.0003007058823529412
metabolic process | 7511 | 85 | 64.51 | + | 0.000929 | 0.0123673125 |  | intracellular protein transport | 36 | 17.07 | + | 2.12e-05 | 0.0003007058823529412
intracellular signaling cascade | 1017 | 19 | 8.73 | + | 0.00127 | 0.01591235294117647 |  | neurotransmitter secretion | 13 | 3.17 | + | 2.4e-05 | 0.0003007058823529412
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 3297 | 15 | 28.32 | - | 0.00245 | 0.02899166666666667 |  | exocytosis | 14 | 3.77 | + | 3.42e-05 | 0.0004047
cellular process | 5326 | 63 | 45.74 | + | 0.00245 | 0.02899166666666667 |  | translation | 16 | 4.82 | + | 3.61e-05 | 0.0004047
glycolysis | 72 | 4 | 0.62 | + | 0.00364 | 0.038766 |  | protein amino acid phosphorylation | 22 | 8.96 | + | 0.000119 | 0.00126735
cell motion | 448 | 10 | 3.85 | + | 0.00568 | 0.05761142857142857 |  | neuronal action potential propagation | 5 | 0.65 | + | 0.000562 | 0.005630608695652174
[NAME] process | 7131 | 77 | 61.24 | + | 0.00812 | 0.07861636363636365 |  | response to stimulus | 4 | 15.18 | - | 0.000586 | 0.005630608695652174
monosaccharide metabolic process | 151 | 5 | 1.3 | + | 0.0102 | 0.09446086956521739 |  | immune system process | 9 | 22.82 | - | 0.000608 | 0.005630608695652174
endocytosis | 353 | 8 | 3.03 | + | 0.0118 | 0.09994615384615385 |  | Unclassified | 72 | 96.74 | - | 0.000854 | 0.00757925
generation of precursor metabolites and energy | 285 | 7 | 2.45 | + | 0.0121 | 0.09994615384615385 |  | synaptic vesicle exocytosis | 8 | 1.99 | + | 0.000993 | 0.00846036
[NAME] process | 55 | 3 | 0.47 | + | 0.0122 | 0.09994615384615385 |  | ion transport | 19 | 8.55 | + | 0.00113 | 0.009257307692307691
G-protein coupled receptor protein signaling pathway | 680 | 1 | 5.84 | - | 0.0185 | 0.1452964285714286 |  | [NAME] process | 2 | 0.08 | + | 0.00315 | 0.02485
synaptic transmission | 462 | 9 | 3.97 | + | 0.0191 | 0.1452964285714286 |  | cation transport | 15 | 6.89 | + | 0.0044 | 0.03347142857142858
system development | 1206 | 4 | 10.36 | - | 0.0203 | 0.1477258064516129 |  | DNA metabolic process | 0 | 5.08 | - | 0.00595 | 0.04370172413793104
tricarboxylic acid cycle | 26 | 2 | 0.22 | + | 0.0214 | 0.1477258064516129 |  | intracellular signaling cascade | 24 | 13.84 | + | 0.00672 | 0.047712
cell-cell adhesion | 442 | 0 | 3.8 | - | 0.0215 | 0.1477258064516129 |  | [NAME] process | 78 | 97.06 | - | 0.00859 | 0.0580425
neuromuscular synaptic transmission | 27 | 2 | 0.23 | + | 0.023 | 0.15309375 |  | RNA metabolic process | 1 | 6.72 | - | 0.00872 | 0.0580425
cell surface receptor linked signal transduction | 1628 | 7 | 13.98 | - | 0.027 | 0.1742727272727273 |  | immune response | 1 | 6.47 | - | 0.011 | 0.071
fatty acid metabolic process | 204 | 5 | 1.75 | + | 0.0323 | 0.20235 |  | dorsal/ventral axis specification | 3 | 0.5 | + | 0.0146 | 0.09146470588235293
reproduction | 368 | 0 | 3.16 | - | 0.0412 | 0.2507314285714286 |  | cell adhesion | 20 | 11.76 | + | 0.0155 | 0.09432857142857143
protein modification process | 1177 | 16 | 10.11 | + | 0.0472 | 0.2792666666666667 |  | metabolic process | 85 | 102.23 | - | 0.0171 | 0.101175
tRNA aminoacylation for protein translation | 42 | 2 | 0.36 | + | 0.0512 | 0.2897921052631579 |  | proteolysis | 6 | 13.43 | - | 0.0179 | 0.1025763157894737
neurotransmitter secretion | 233 | 5 | 2 | + | 0.0517 | 0.2897921052631579 |  | [NAME] process | 51 | 38.15 | + | 0.0183 | 0.1025763157894737
gamete generation | 335 | 0 | 2.88 | - | 0.0549 | 0.297135 |  | protein modification process | 25 | 16.02 | + | 0.0192 | 0.1048615384615385
purine base metabolic process | 100 | 3 | 0.86 | + | 0.0558 | 0.297135 |  | muscle contraction | 9 | 4.1 | + | 0.0234 | 0.1220853658536585
response to stimulus | 1115 | 15 | 9.58 | + | 0.0578 | 0.2977046511627907 |  | cell surface receptor linked signal transduction | 32 | 22.16 | + | 0.0235 | 0.1220853658536585
protein amino acid phosphorylation | 658 | 10 | 5.65 | + | 0.0588 | 0.2977046511627907 |  | G-protein coupled receptor protein signaling pathway | 16 | 9.26 | + | 0.0252 | 0.1278
system process | 1410 | 18 | 12.11 | + | 0.0601 | 0.2977046511627907 |  | anion transport | 4 | 1.22 | + | 0.0356 | 0.1763441860465116
pentose-phosphate shunt | 8 | 1 | 0.07 | + | 0.0664 | 0.3214363636363636 |  | [NAME] | 2 | 0.3 | + | 0.0367 | 0.1776613636363636
RNA metabolic process | 494 | 1 | 4.24 | - | 0.0729 | 0.34035625 |  | [NAME] | 2 | 0.3 | + | 0.0367 | 0.1776613636363636
carbohydrate metabolic process | 687 | 10 | 5.9 | + | 0.0737 | 0.34035625 |  | phosphate metabolic process | 5 | 1.91 | + | 0.0439 | 0.2032760869565217
mRNA processing | 298 | 0 | 2.56 | - | 0.0759 | 0.34035625 |  | protein targeting | 5 | 1.96 | + | 0.0485 | 0.21965625
respiratory electron transport chain | 262 | 5 | 2.25 | + | 0.0767 | 0.34035625 |  | tricarboxylic acid cycle | 2 | 0.35 | + | 0.0495 | 0.21965625
cellular amino acid metabolic process | 266 | 5 | 2.28 | + | 0.0806 | 0.3503632653061224 |  | nuclear mRNA splicing, via spliceosome | 0 | 2.97 | - | 0.0506 | 0.2199551020408163
cellular amino acid and derivative metabolic process | 266 | 5 | 2.28 | + | 0.0806 | 0.3503632653061224 |  | cytokinesis | 4 | 1.39 | + | 0.052 | 0.22152
ion transport | 628 | 2 | 5.39 | - | 0.0916 | 0.3760269230769231 |  | calcium-mediated signaling | 5 | 2.15 | + | 0.0665 | 0.2777352941176471
exocytosis | 277 | 5 | 2.38 | + | 0.0918 | 0.3760269230769231 |  | DNA repair | 0 | 2.61 | - | 0.0724 | 0.2965615384615385
cellular defense response | 264 | 0 | 2.27 | - | 0.102 | 0.4066363636363636 |  | nitric oxide biosynthetic process | 1 | 0.08 | + | 0.0784 | 0.3150792452830189
receptor-mediated endocytosis | 131 | 3 | 1.13 | + | 0.104 | 0.4066363636363636 |  | nitric oxide mediated signal transduction | 1 | 0.08 | + | 0.0784 | 0.3150792452830189
cytokine-mediated signaling pathway | 261 | 0 | 2.24 | - | 0.105 | 0.4066363636363636 |  | mRNA processing | 1 | 4.06 | - | 0.086 | 0.3330545454545454
mesoderm development | 754 | 3 | 6.48 | - | 0.109 | 0.4145892857142857 |  | mitosis | 9 | 5.31 | + | 0.088 | 0.3347142857142857
nervous system development | 738 | 3 | 6.34 | - | 0.119 | 0.4440508474576271 |  | macrophage activation | 0 | 2.29 | - | 0.101 | 0.377421052631579
muscle contraction | 301 | 5 | 2.59 | + | 0.119 | 0.4440508474576271 |  | mesoderm development | 6 | 10.26 | - | 0.11 | 0.4039655172413793
neurological system process | 1155 | 14 | 9.92 | + | 0.123 | 0.4440508474576271 |  | DNA replication | 0 | 2.11 | - | 0.12 | 0.4164626865671642
developmental process | 2093 | 23 | 17.98 | + | 0.131 | 0.4609180327868853 |  | reproduction | 2 | 5.01 | - | 0.122 | 0.4164626865671642
cell adhesion | 864 | 4 | 7.42 | - | 0.132 | 0.4609180327868853 |  | response to stress | 1 | 3.61 | - | 0.123 | 0.4164626865671642
oxidative phosphorylation | 76 | 2 | 0.65 | + | 0.139 | 0.4775322580645162 |  | cellular defense response | 1 | 3.59 | - | 0.125 | 0.4164626865671642
nuclear mRNA splicing, via spliceosome | 218 | 0 | 1.87 | - | 0.152 | 0.5139047619047619 |  | general transcription from RNA polymerase II promoter | 2 | 0.61 | + | 0.126 | 0.4164626865671642
pattern specification process | 207 | 0 | 1.78 | - | 0.167 | 0.5505230769230769 |  | monosaccharide metabolic process | 0 | 2.06 | - | 0.127 | 0.4164626865671642
DNA metabolic process | 373 | 1 | 3.2 | - | 0.168 | 0.5505230769230769 |  | cytokine-mediated signaling pathway | 1 | 3.55 | - | 0.129 | 0.4164626865671642
coenzyme metabolic process | 92 | 2 | 0.79 | + | 0.187 | 0.5951470588235294 |  | organelle organization | 1 | 3.55 | - | 0.129 | 0.4164626865671642
cation transport | 506 | 2 | 4.35 | - | 0.188 | 0.5951470588235294 |  | segment specification | 0 | 2.03 | - | 0.131 | 0.4164626865671642
translation | 354 | 5 | 3.04 | + | 0.19 | 0.5951470588235294 |  | oxygen and reactive oxygen species metabolic process | 2 | 0.69 | + | 0.154 | 0.4823823529411765
immune system process | 1677 | 18 | 14.4 | + | 0.194 | 0.5988695652173913 |  | [NAME] receptor [NAME] signaling pathway | 1 | 3.29 | - | 0.158 | 0.4877391304347827
spermatogenesis | 187 | 0 | 1.61 | - | 0.199 | 0.6055285714285714 |  | gamete generation | 2 | 4.56 | - | 0.165 | 0.4979594594594594
nuclear transport | 98 | 2 | 0.84 | + | 0.206 | 0.618 |  | MAPKKK cascade | 6 | 3.7 | + | 0.169 | 0.4979594594594594
skeletal system development | 181 | 0 | 1.55 | - | 0.21 | 0.62125 |  | establishment or maintenance of chromatin architecture | 1 | 3.2 | - | 0.17 | 0.4979594594594594
cytokinesis | 102 | 2 | 0.88 | + | 0.219 | 0.639 |  | carbohydrate metabolic process | 6 | 9.35 | - | 0.172 | 0.4979594594594594
angiogenesis | 172 | 0 | 1.48 | - | 0.227 | 0.6533918918918918 |  | nucleobase, nucleoside, nucleotide and nucleic acid transport | 2 | 0.75 | + | 0.173 | 0.4979594594594594
mitosis | 390 | 5 | 3.35 | + | 0.245 | 0.6902278481012658 |  | localization | 2 | 0.76 | + | 0.178 | 0.50552
cell communication | 3631 | 35 | 31.18 | + | 0.252 | 0.6902278481012658 |  | B cell mediated immunity | 0 | 1.7 | - | 0.181 | 0.5072763157894736
RNA localization | 34 | 1 | 0.29 | + | 0.253 | 0.6902278481012658 |  | lipid transport | 4 | 2.26 | + | 0.192 | 0.5311168831168831
fatty acid biosynthetic process | 34 | 1 | 0.29 | + | 0.253 | 0.6902278481012658 |  | generation of precursor metabolites and energy | 6 | 3.88 | + | 0.195 | 0.5325000000000001
blood coagulation | 158 | 0 | 1.36 | - | 0.256 | 0.6902278481012658 |  | carbohydrate transport | 2 | 0.87 | + | 0.217 | 0.5837777777777778
response to external stimulus | 158 | 0 | 1.36 | - | 0.256 | 0.6902278481012658 |  | nitrogen compound metabolic process | 1 | 0.24 | + | 0.217 | 0.5837777777777778
DNA replication | 155 | 0 | 1.33 | - | 0.263 | 0.6915925925925926 |  | cellular amino acid catabolic process | 2 | 0.88 | + | 0.222 | 0.5837777777777778
embryonic development | 151 | 0 | 1.3 | - | 0.272 | 0.7065365853658537 |  | phospholipid metabolic process | 1 | 2.8 | - | 0.229 | 0.5948414634146342
segment specification | 149 | 0 | 1.28 | - | 0.277 | 0.7108554216867471 |  | fatty acid metabolic process | 1 | 2.78 | - | 0.234 | 0.5964
ectoderm development | 827 | 5 | 7.1 | - | 0.282 | 0.7150714285714285 |  | extracellular transport | 0 | 1.42 | - | 0.242 | 0.5964
cell cycle | 1152 | 12 | 9.89 | + | 0.287 | 0.7191882352941176 |  | protein amino acid glycosylation | 1 | 2.72 | - | 0.243 | 0.5964
[NAME] process | 836 | 9 | 7.18 | + | 0.292 | 0.7232093023255813 |  | natural killer cell activation | 0 | 1.4 | - | 0.245 | 0.5964
cell-cell signaling | 862 | 9 | 7.4 | + | 0.323 | 0.7907931034482759 |  | induction of apoptosis | 5 | 3.36 | + | 0.248 | 0.5964
B cell mediated immunity | 125 | 0 | 1.07 | - | 0.341 | 0.8208876404494383 |  | protein folding | 1 | 2.68 | - | 0.251 | 0.5964
organelle organization | 261 | 1 | 2.24 | - | 0.343 | 0.8208876404494383 |  | steroid metabolic process | 1 | 2.68 | - | 0.251 | 0.5964
protein targeting | 144 | 2 | 1.24 | + | 0.351 | 0.8306999999999999 |  | hemopoiesis | 0 | 1.37 | - | 0.252 | 0.5964
synaptic vesicle exocytosis | 146 | 2 | 1.25 | + | 0.357 | 0.8356153846153845 |  | purine base metabolic process | 0 | 1.36 | - | 0.256 | 0.5992087912087912
induction of apoptosis | 247 | 1 | 2.12 | - | 0.372 | 0.8402752293577982 |  | nuclear transport | 0 | 1.33 | - | 0.263 | 0.6089021739130436
nucleobase, nucleoside, nucleotide and nucleic acid transport | 55 | 1 | 0.47 | + | 0.377 | 0.8402752293577982 |  | spermatogenesis | 1 | 2.55 | - | 0.277 | 0.6300315789473685
localization | 56 | 1 | 0.48 | + | 0.382 | 0.8402752293577982 |  | [NAME] process | 0 | 1.28 | - | 0.277 | 0.6300315789473685
tRNA metabolic process | 56 | 1 | 0.48 | + | 0.382 | 0.8402752293577982 |  | visual perception | 5 | 3.54 | + | 0.281 | 0.6300315789473685
[NAME] receptor [NAME] signaling pathway | 242 | 1 | 2.08 | - | 0.383 | 0.8402752293577982 |  | coenzyme metabolic process | 0 | 1.25 | - | 0.285 | 0.63234375
visual perception | 260 | 3 | 2.23 | + | 0.387 | 0.8402752293577982 |  | response to interferon-gamma | 0 | 1.24 | - | 0.289 | 0.6346082474226804
establishment or maintenance of chromatin architecture | 235 | 1 | 2.02 | - | 0.399 | 0.8402752293577982 |  | muscle organ development | 1 | 2.45 | - | 0.296 | 0.6369117647058824
heart development | 105 | 0 | 0.9 | - | 0.405 | 0.8402752293577982 |  | JAK-STAT cascade | 0 | 1.21 | - | 0.297 | 0.6369117647058824
extracellular transport | 104 | 0 | 0.89 | - | 0.408 | 0.8402752293577982 |  | cellular component morphogenesis | 12 | 9.99 | + | 0.3 | 0.6369117647058824
natural killer cell activation | 103 | 0 | 0.88 | - | 0.412 | 0.8402752293577982 |  | anatomical structure morphogenesis | 12 | 9.99 | + | 0.3 | 0.6369117647058824
immune response | 475 | 3 | 4.08 | - | 0.416 | 0.8402752293577982 |  | homeostatic process | 0 | 1.18 | - | 0.305 | 0.6369117647058824
lipid transport | 166 | 2 | 1.43 | + | 0.418 | 0.8402752293577982 |  | neuromuscular synaptic transmission | 1 | 0.37 | + | 0.308 | 0.6369320388349514
hemopoiesis | 101 | 0 | 0.87 | - | 0.419 | 0.8402752293577982 |  | transcription initiation from RNA polymerase II promoter | 0 | 1.16 | - | 0.314 | 0.642981308411215
signal transduction | 3451 | 31 | 29.64 | + | 0.423 | 0.8402752293577982 |  | cell-matrix adhesion | 0 | 1.14 | - | 0.318 | 0.642981308411215
polysaccharide metabolic process | 225 | 1 | 1.93 | - | 0.423 | 0.8402752293577982 |  | response to toxin | 0 | 1.13 | - | 0.322 | 0.642981308411215
cellular amino acid biosynthetic process | 64 | 1 | 0.55 | + | 0.423 | 0.8402752293577982 |  | system development | 14 | 16.41 | - | 0.323 | 0.642981308411215
cellular amino acid catabolic process | 65 | 1 | 0.56 | + | 0.428 | 0.8402752293577982 |  | meiosis | 2 | 1.21 | + | 0.342 | 0.6745
JNK cascade | 98 | 0 | 0.84 | - | 0.43 | 0.8402752293577982 |  | endocytosis | 6 | 4.8 | + | 0.349 | 0.6751339285714285
blood circulation | 96 | 0 | 0.82 | - | 0.438 | 0.8454961832061069 |  | DNA recombination | 0 | 1.05 | - | 0.35 | 0.6751339285714285
anion transport | 90 | 0 | 0.77 | - | 0.461 | 0.8454961832061069 |  | rRNA metabolic process | 0 | 1.05 | - | 0.35 | 0.6751339285714285
JAK-STAT cascade | 89 | 0 | 0.76 | - | 0.465 | 0.8454961832061069 |  | oxidative phosphorylation | 0 | 1.03 | - | 0.355 | 0.6751339285714285
complement activation | 73 | 1 | 0.63 | + | 0.466 | 0.8454961832061069 |  | blood coagulation | 1 | 2.15 | - | 0.366 | 0.6793965517241379
apoptosis | 681 | 5 | 5.85 | - | 0.468 | 0.8454961832061069 |  | response to external stimulus | 1 | 2.15 | - | 0.366 | 0.6793965517241379
phospholipid metabolic process | 206 | 1 | 1.77 | - | 0.471 | 0.8454961832061069 |  | negative regulation of apoptosis | 1 | 2.14 | - | 0.369 | 0.6793965517241379
homeostatic process | 87 | 0 | 0.75 | - | 0.473 | 0.8454961832061069 |  | protein complex assembly | 0 | 0.99 | - | 0.37 | 0.6793965517241379
proteolysis | 987 | 9 | 8.48 | + | 0.475 | 0.8454961832061069 |  | glycolysis | 0 | 0.98 | - | 0.375 | 0.6826923076923077
transcription initiation from RNA polymerase II promoter | 85 | 0 | 0.73 | - | 0.481 | 0.8454961832061069 |  | antigen processing and presentation | 0 | 0.98 | - | 0.375 | 0.6826923076923077
DNA recombination | 77 | 1 | 0.66 | + | 0.484 | 0.8454961832061069 |  | embryonic development | 1 | 2.06 | - | 0.39 | 0.6980672268907564
I-kappaB kinase/NF-kappaB cascade | 84 | 0 | 0.72 | - | 0.485 | 0.8454961832061069 |  | RNA catabolic process | 0 | 0.93 | - | 0.396 | 0.7029
nerve-nerve synaptic transmission | 84 | 0 | 0.72 | - | 0.485 | 0.8454961832061069 |  | fertilization | 0 | 0.93 | - | 0.396 | 0.7029
protein amino acid glycosylation | 200 | 1 | 1.72 | - | 0.487 | 0.8454961832061069 |  | polysaccharide metabolic process | 2 | 3.06 | - | 0.408 | 0.7066190476190476
steroid metabolic process | 197 | 1 | 1.69 | - | 0.495 | 0.8454961832061069 |  | cell motion | 7 | 6.1 | + | 0.41 | 0.7066190476190476
vitamin transport | 79 | 0 | 0.68 | - | 0.507 | 0.8454961832061069 |  | [NAME] process | 10 | 11.38 | - | 0.412 | 0.7066190476190476
anterior/posterior axis specification | 79 | 0 | 0.68 | - | 0.507 | 0.8454961832061069 |  | angiogenesis | 3 | 2.34 | + | 0.415 | 0.7066190476190476
DNA repair | 192 | 1 | 1.65 | - | 0.508 | 0.8454961832061069 |  | apoptosis | 8 | 9.27 | - | 0.418 | 0.7066190476190476
response to toxin | 83 | 1 | 0.71 | + | 0.51 | 0.8454961832061069 |  | nervous system development | 11 | 10.04 | + | 0.423 | 0.7094409448818898
cell-matrix adhesion | 84 | 1 | 0.72 | + | 0.515 | 0.8454961832061069 |  | skeletal system development | 3 | 2.46 | + | 0.447 | 0.7438359375
rRNA metabolic process | 77 | 0 | 0.66 | - | 0.516 | 0.8454961832061069 |  | tRNA metabolic process | 0 | 0.76 | - | 0.466 | 0.7694418604651163
glycogen metabolic process | 85 | 1 | 0.73 | + | 0.519 | 0.8454961832061069 |  | [NAME] process | 0 | 0.75 | - | 0.473 | 0.7745454545454545
female gamete generation | 76 | 0 | 0.65 | - | 0.52 | 0.8454961832061069 |  | respiratory electron transport chain | 4 | 3.57 | + | 0.478 | 0.7745454545454545
meiosis | 89 | 1 | 0.76 | + | 0.535 | 0.8567333333333333 |  | amino acid transport | 1 | 0.65 | + | 0.48 | 0.7745454545454545
antigen processing and presentation | 72 | 0 | 0.62 | - | 0.538 | 0.8567333333333333 |  | chromosome segregation | 1 | 1.74 | - | 0.48 | 0.7745454545454545
muscle organ development | 180 | 1 | 1.55 | - | 0.542 | 0.8567333333333333 |  | cellular amino acid metabolic process | 4 | 3.62 | + | 0.49 | 0.778389705882353
response to interferon-gamma | 91 | 1 | 0.78 | + | 0.543 | 0.8567333333333333 |  | cellular amino acid and derivative metabolic process | 4 | 3.62 | + | 0.49 | 0.778389705882353
[NAME] process | 93 | 1 | 0.8 | + | 0.551 | 0.8597173913043479 |  | cell cycle | 15 | 15.68 | - | 0.497 | 0.778389705882353
[NAME] process | 94 | 1 | 0.81 | + | 0.555 | 0.8597173913043479 |  | developmental process | 28 | 28.49 | - | 0.511 | 0.791804347826087
RNA catabolic process | 68 | 0 | 0.58 | - | 0.557 | 0.8597173913043479 |  | regulation of biological process | 0 | 0.67 | - | 0.513 | 0.791804347826087
fertilization | 68 | 0 | 0.58 | - | 0.557 | 0.8597173913043479 |  | regulation of vasoconstriction | 0 | 0.67 | - | 0.513 | 0.791804347826087
macrophage activation | 168 | 1 | 1.44 | - | 0.577 | 0.87 |  | cellular component organization | 13 | 13.46 | - | 0.521 | 0.7926642857142857
carbohydrate transport | 64 | 0 | 0.55 | - | 0.577 | 0.87 |  | receptor-mediated endocytosis | 2 | 1.78 | + | 0.533 | 0.7983776223776224
sensory perception | 384 | 3 | 3.3 | - | 0.58 | 0.87 |  | cyclic nucleotide metabolic process | 0 | 0.63 | - | 0.534 | 0.7983776223776224
MAPKKK cascade | 272 | 2 | 2.34 | - | 0.586 | 0.8728531468531469 |  | pattern specification process | 3 | 2.82 | + | 0.536 | 0.7983776223776224
calcium-mediated signaling | 158 | 1 | 1.36 | - | 0.606 | 0.8945999999999998 |  | cellular calcium ion homeostasis | 0 | 0.61 | - | 0.542 | 0.7997806451612903
negative regulation of apoptosis | 157 | 1 | 1.35 | - | 0.609 | 0.8945999999999998 |  | ectoderm development | 11 | 11.26 | - | 0.548 | 0.7997806451612903
oxygen and reactive oxygen species metabolic process | 51 | 0 | 0.44 | - | 0.645 | 0.93586875 |  | vitamin metabolic process | 0 | 0.6 | - | 0.549 | 0.7997806451612903
regulation of biological process | 49 | 0 | 0.42 | - | 0.656 | 0.93586875 |  | [NAME] receptor protein serine/threonine kinase signaling pathway | 0 | 0.6 | - | 0.549 | 0.7997806451612903
regulation of vasoconstriction | 49 | 0 | 0.42 | - | 0.656 | 0.93586875 |  | RNA elongation from RNA polymerase II promoter | 0 | 0.59 | - | 0.557 | 0.7997806451612903
phosphate metabolic process | 140 | 1 | 1.2 | - | 0.662 | 0.93586875 |  | defense response to bacterium | 0 | 0.59 | - | 0.557 | 0.7997806451612903
neuronal action potential propagation | 48 | 0 | 0.41 | - | 0.662 | 0.93586875 |  | tRNA aminoacylation for protein translation | 0 | 0.57 | - | 0.564 | 0.7997806451612903
amino acid transport | 48 | 0 | 0.41 | - | 0.662 | 0.93586875 |  | phagocytosis | 0 | 0.56 | - | 0.572 | 0.7997806451612903
cyclic nucleotide metabolic process | 46 | 0 | 0.4 | - | 0.673 | 0.93586875 |  | sensory perception | 5 | 5.23 | - | 0.576 | 0.7997806451612903
general transcription from RNA polymerase II promoter | 45 | 0 | 0.39 | - | 0.679 | 0.93586875 |  | sensory perception of sound | 0 | 0.54 | - | 0.58 | 0.7997806451612903
cellular calcium ion homeostasis | 45 | 0 | 0.39 | - | 0.679 | 0.93586875 |  | heart development | 1 | 1.43 | - | 0.581 | 0.7997806451612903
vitamin metabolic process | 44 | 0 | 0.38 | - | 0.685 | 0.93586875 |  | cellular amino acid biosynthetic process | 1 | 0.87 | + | 0.582 | 0.7997806451612903
[NAME] receptor protein serine/threonine kinase signaling pathway | 44 | 0 | 0.38 | - | 0.685 | 0.93586875 |  | mRNA 3'-end processing | 0 | 0.53 | - | 0.588 | 0.8028461538461539
RNA elongation from RNA polymerase II promoter | 43 | 0 | 0.37 | - | 0.691 | 0.93586875 |  | cell-cell adhesion | 6 | 6.02 | - | 0.604 | 0.8182317073170732
defense response to bacterium | 43 | 0 | 0.37 | - | 0.691 | 0.93586875 |  | sensory perception of pain | 0 | 0.5 | - | 0.604 | 0.8182317073170732
chromosome segregation | 128 | 1 | 1.1 | - | 0.699 | 0.93586875 |  | JNK cascade | 1 | 1.33 | - | 0.615 | 0.8182317073170732
phagocytosis | 41 | 0 | 0.35 | - | 0.703 | 0.93586875 |  | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 0 | 0.48 | - | 0.621 | 0.8182317073170732
sensory perception of sound | 40 | 0 | 0.34 | - | 0.709 | 0.9379937888198757 |  | blood circulation | 1 | 1.31 | - | 0.624 | 0.8182317073170732
mRNA 3'-end processing | 39 | 0 | 0.33 | - | 0.715 | 0.9400925925925925 |  | RNA localization | 0 | 0.46 | - | 0.629 | 0.8182317073170732
sensory perception of pain | 37 | 0 | 0.32 | - | 0.728 | 0.9513128834355827 |  | fatty acid biosynthetic process | 0 | 0.46 | - | 0.629 | 0.8182317073170732
dorsal/ventral axis specification | 37 | 0 | 0.32 | - | 0.728 | 0.9513128834355827 |  | complement activation | 1 | 0.99 | + | 0.63 | 0.8182317073170732
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 35 | 0 | 0.3 | - | 0.74 | 0.9552727272727273 |  | cellular glucose homeostasis | 0 | 0.45 | - | 0.638 | 0.819921686746988
cellular glucose homeostasis | 33 | 0 | 0.28 | - | 0.753 | 0.9661987951807229 |  | [NAME] process | 1 | 1.27 | - | 0.639 | 0.819921686746988
mRNA polyadenylation | 32 | 0 | 0.27 | - | 0.76 | 0.9693413173652694 |  | mRNA polyadenylation | 0 | 0.44 | - | 0.647 | 0.8252155688622755
gluconeogenesis | 30 | 0 | 0.26 | - | 0.773 | 0.9790526315789474 |  | gluconeogenesis | 0 | 0.41 | - | 0.665 | 0.843125
mRNA transcription | 29 | 0 | 0.25 | - | 0.779 | 0.9790526315789474 |  | mRNA transcription | 0 | 0.39 | - | 0.674 | 0.8445263157894738
mammary gland development | 29 | 0 | 0.25 | - | 0.779 | 0.9790526315789474 |  | mammary gland development | 0 | 0.39 | - | 0.674 | 0.8445263157894738
endoderm development | 28 | 0 | 0.24 | - | 0.786 | 0.9790526315789474 |  | glycogen metabolic process | 1 | 1.16 | - | 0.678 | 0.8445263157894738
protein amino acid acetylation | 27 | 0 | 0.23 | - | 0.793 | 0.982029069767442 |  | I-kappaB kinase/NF-kappaB cascade | 1 | 1.14 | - | 0.683 | 0.8458081395348838
mitochondrion organization | 26 | 0 | 0.22 | - | 0.8 | 0.9822342857142858 |  | endoderm development | 0 | 0.38 | - | 0.683 | 0.8458081395348838
mitochondrial transport | 26 | 0 | 0.22 | - | 0.8 | 0.9822342857142858 |  | protein amino acid acetylation | 0 | 0.37 | - | 0.692 | 0.8460502793296089
fatty acid beta-oxidation | 25 | 0 | 0.21 | - | 0.807 | 0.9822342857142858 |  | mitochondrion organization | 0 | 0.35 | - | 0.702 | 0.8460502793296089
acyl-CoA metabolic process | 24 | 0 | 0.21 | - | 0.814 | 0.9851249999999999 |  | mitochondrial transport | 0 | 0.35 | - | 0.702 | 0.8460502793296089
[NAME] process | 22 | 0 | 0.19 | - | 0.828 | 0.9880833333333333 |  | vitamin transport | 1 | 1.08 | - | 0.708 | 0.8460502793296089
[NAME] | 22 | 0 | 0.19 | - | 0.828 | 0.9880833333333333 |  | anterior/posterior axis specification | 1 | 1.08 | - | 0.708 | 0.8460502793296089
[NAME] | 22 | 0 | 0.19 | - | 0.828 | 0.9880833333333333 |  | fatty acid beta-oxidation | 0 | 0.34 | - | 0.711 | 0.8460502793296089
vitamin biosynthetic process | 21 | 0 | 0.18 | - | 0.835 | 0.9880833333333333 |  | acyl-CoA metabolic process | 0 | 0.33 | - | 0.721 | 0.8508232044198895
protein amino acid lipidation | 21 | 0 | 0.18 | - | 0.835 | 0.9880833333333333 |  | female gamete generation | 1 | 1.03 | - | 0.723 | 0.8508232044198895
termination of RNA polymerase II transcription | 19 | 0 | 0.16 | - | 0.849 | 0.9932406417112299 |  | [NAME] process | 0 | 0.3 | - | 0.741 | 0.8672142857142857
lysosomal transport | 18 | 0 | 0.15 | - | 0.857 | 0.9932406417112299 |  | vitamin biosynthetic process | 0 | 0.29 | - | 0.751 | 0.8741147540983606
nitrogen compound metabolic process | 18 | 0 | 0.15 | - | 0.857 | 0.9932406417112299 |  | protein amino acid lipidation | 0 | 0.29 | - | 0.751 | 0.8741147540983606
sex determination | 17 | 0 | 0.15 | - | 0.864 | 0.9932406417112299 |  | termination of RNA polymerase II transcription | 0 | 0.26 | - | 0.772 | 0.8888432432432433
regulation of carbohydrate metabolic process | 17 | 0 | 0.15 | - | 0.864 | 0.9932406417112299 |  | lysosomal transport | 0 | 0.24 | - | 0.783 | 0.8966612903225806
phosphate transport | 16 | 0 | 0.14 | - | 0.872 | 0.9932406417112299 |  | sex determination | 0 | 0.23 | - | 0.793 | 0.9032566844919787
gut mesoderm development | 15 | 0 | 0.13 | - | 0.879 | 0.9953853658536586 |  | regulation of carbohydrate metabolic process | 0 | 0.23 | - | 0.793 | 0.9032566844919787
peroxisomal transport | 14 | 0 | 0.12 | - | 0.887 | 0.9953853658536586 |  | phosphate transport | 0 | 0.22 | - | 0.804 | 0.9060952380952382
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 14 | 0 | 0.12 | - | 0.887 | 0.9953853658536586 |  | gut mesoderm development | 0 | 0.2 | - | 0.815 | 0.9136578947368421
sensory perception of chemical stimulus | 12 | 0 | 0.1 | - | 0.902 | 0.9953853658536586 |  | peroxisomal transport | 0 | 0.19 | - | 0.826 | 0.9211413612565444
protein amino acid methylation | 10 | 0 | 0.09 | - | 0.918 | 0.9953853658536586 |  | regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 0 | 0.19 | - | 0.826 | 0.9211413612565444
protein amino acid ADP-ribosylation | 10 | 0 | 0.09 | - | 0.918 | 0.9953853658536586 |  | sensory perception of chemical stimulus | 0 | 0.16 | - | 0.849 | 0.936979274611399
DNA catabolic process | 10 | 0 | 0.09 | - | 0.918 | 0.9953853658536586 |  | protein amino acid methylation | 0 | 0.14 | - | 0.873 | 0.9520454545454545
sensory perception of taste | 10 | 0 | 0.09 | - | 0.918 | 0.9953853658536586 |  | protein amino acid ADP-ribosylation | 0 | 0.14 | - | 0.873 | 0.9520454545454545
regulation of liquid surface tension | 9 | 0 | 0.08 | - | 0.926 | 0.9953853658536586 |  | DNA catabolic process | 0 | 0.14 | - | 0.873 | 0.9520454545454545
response to pheromone | 7 | 0 | 0.06 | - | 0.942 | 0.9953853658536586 |  | sensory perception of taste | 0 | 0.14 | - | 0.873 | 0.9520454545454545
pinocytosis | 7 | 0 | 0.06 | - | 0.942 | 0.9953853658536586 |  | regulation of liquid surface tension | 0 | 0.12 | - | 0.885 | 0.9520454545454545
transcription, RNA-dependent | 6 | 0 | 0.05 | - | 0.95 | 0.9953853658536586 |  | pentose-phosphate shunt | 0 | 0.11 | - | 0.897 | 0.960105527638191
nitric oxide biosynthetic process | 6 | 0 | 0.05 | - | 0.95 | 0.9953853658536586 |  | response to pheromone | 0 | 0.1 | - | 0.909 | 0.9680850000000001
regulation of amino acid metabolic process | 6 | 0 | 0.05 | - | 0.95 | 0.9953853658536586 |  | pinocytosis | 0 | 0.1 | - | 0.909 | 0.9680850000000001
[NAME] process | 6 | 0 | 0.05 | - | 0.95 | 0.9953853658536586 |  | transcription, RNA-dependent | 0 | 0.08 | - | 0.922 | 0.9704487804878049
unsaturated fatty acid biosynthetic process | 6 | 0 | 0.05 | - | 0.95 | 0.9953853658536586 |  | regulation of amino acid metabolic process | 0 | 0.08 | - | 0.922 | 0.9704487804878049
nitric oxide mediated signal transduction | 6 | 0 | 0.05 | - | 0.95 | 0.9953853658536586 |  | unsaturated fatty acid biosynthetic process | 0 | 0.08 | - | 0.922 | 0.9704487804878049
disaccharide metabolic process | 5 | 0 | 0.04 | - | 0.958 | 0.9953853658536586 |  | disaccharide metabolic process | 0 | 0.07 | - | 0.934 | 0.9704487804878049
polyphosphate catabolic process | 4 | 0 | 0.03 | - | 0.966 | 0.9988252427184465 |  | polyphosphate catabolic process | 0 | 0.05 | - | 0.947 | 0.9791796116504854
mRNA capping | 3 | 0 | 0.03 | - | 0.975 | 1 |  | mRNA capping | 0 | 0.04 | - | 0.96 | 0.9878260869565217
regulation of phosphate metabolic process | 3 | 0 | 0.03 | - | 0.975 | 1 |  | regulation of phosphate metabolic process | 0 | 0.04 | - | 0.96 | 0.9878260869565217
sensory perception of smell | 2 | 0 | 0.02 | - | 0.983 | 1 |  | sensory perception of smell | 0 | 0.03 | - | 0.973 | 0.991622009569378
nitrogen utilization | 2 | 0 | 0.02 | - | 0.983 | 1 |  | nitrogen utilization | 0 | 0.03 | - | 0.973 | 0.991622009569378
vitamin catabolic process | 1 | 0 | 0.01 | - | 0.991 | 1 |  | vitamin catabolic process | 0 | 0.01 | - | 0.986 | 0.9953459715639811
catabolic process | 1 | 0 | 0.01 | - | 0.991 | 1 |  | catabolic process | 0 | 0.01 | - | 0.986 | 0.9953459715639811
bile acid metabolic process | 1 | 0 | 0.01 | - | 0.991 | 1 |  | bile acid metabolic process | 0 | 0.01 | - | 0.986 | 0.9953459715639811
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