Spreadsheet: 2063e2b7-4d29-41ca-9599-d4ca80494837
Sheet: Sheet1

Table S2.  Analysis of all genes transcribed by B. pahangi-infected mosquitoes | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5
ASAPID | Product | GO biological process | GO molecular function | GO cellular component | Relative [NAME] (Fold Change; p<0.05)
1 Hour
ACN-0181041 | putative: glycine-rich secreted salivary peptide |  |  |  | 7.364
ACN-0182765 | putative: conserved unknown |  |  |  | 2.387
ACN-0185532 | questionable: keratin |  |  |  | 2.208
ACN-0187011 | questionable: keratin 10 |  |  |  | 2.186
ACN-0185889 | unknown |  |  |  | 2.166
ACN-0180814 | conserved unknown |  |  |  | 2.061
ACN-0183034 | conserved unknown |  |  |  | -2.01
ACN-0184910 | thymidylate synthase | [NAME] process;dTMP biosynthetic process;DNA metabolic process;deoxyribonucleotide biosynthetic process | thymidylate synthase activity;oxidoreductase activity |  | -2.6
ACN-0186827 | unknown |  |  |  | -3.05
ACN-0184254 | unknown |  |  |  | -3.94
ACN-0186542 | questionable: stem-loop binding protein |  |  |  | -4.02
ACN-0187935 | putative: conserved unknown |  |  |  | -4.743
ACN-0181159 | unknown |  |  |  | -4.78
ACN-0182237 | unknown |  |  |  | -6.37
ACN-0181552 | questionable: conserved unknown |  |  |  | -6.41
ACN-0187203 | unknown |  |  |  | -6.99
ACN-0187012 | putative: volume-sensitive anion channel | chloride transport;regulation of cell volume | volume-sensitive anion channel activity | cellular_component | -8
ACN-0187461 | thioredoxin | [NAME] redox homeostasis | electron carrier [NAME] disulfide oxidoreductase activity;thiol-disulfide exchange intermediate activity | [NAME] | -8.7
ACN-0185544 | calcium-independent phospholipase | immune response | tumor necrosis factor receptor binding;calcium-independent phospholipase A2 activity | lysosome;beta-galactosidase complex | -9.17
ACN-0180368 | putative: beta-galactosidase | carbohydrate metabolic process;salivary gland cell autophagic cell death;autophagic cell death | beta-galactosidase activity |  | -10.06
ACN-0184261 | questionable: kinesin associated protein 3 |  |  |  | -10.66
ACN-0187844 | conserved unknown |  |  |  | -14.1
ACN-0183657 | unknown |  |  |  | -16.75
ACN-0188201 | putative: conserved unknown |  |  |  | -18.12
ACN-0185665 | unknown |  |  |  | -18.59
ACN-0187446 | unknown |  |  |  | -19.8
ACN-0181783 | putative: conserved unknown |  |  |  | -20.75
ACN-0184428 | conserved unknown |  |  |  | -22.08
ACN-0181848 | unknown |  |  |  | -32.68
[NAME] | questionable: transcription regulator |  |  |  | -34.01
ACN-0182772 | unknown |  |  |  | -50.25
3 Hour
[NAME] | questionable: conserved unknown |  |  |  | 14.46
ACN-0187707 | dimethylaniline monooxygenase (N-oxide forming) | [NAME] acid metabolic process | monooxygenase activity;dimethylaniline monooxygenase (N-oxide-forming) activity | mitochondrion;microsome;cytosol | 10.65
ACN-0185532 | questionable: keratin |  |  |  | 9.388
ACN-0187239 | putative: conserved unknown |  |  |  | 8.078
ACN-0180573 | unknown |  |  |  | 7.822
ACN-0185889 | unknown |  |  |  | 7.688
ACN-0186260 | conserved unknown |  |  |  | 7.513
ACN-0186385 | putative: conserved unknown |  |  |  | 7.07
ACN-0181082 | putative: conserved unknown |  |  |  | 6.93
ACN-0181025 | questionable: conserved unknown |  |  |  | 5.928
ACN-0187011 | questionable: keratin 10 |  |  |  | 5.291
ACN-0184331 | unknown |  |  |  | 5.196
ACN-0187656 | unknown |  |  |  | 5.078
ACN-0182511 | unknown |  |  |  | 4.554
ACN-0184394 | putative: serine protease | proteolysis | trypsin activity;monophenol monooxygenase activator activity |  | 4.546
ACN-0182295 | questionable: conserved unknown |  |  |  | 4.414
ACN-0181325 | serine protease | proteolysis | serine-type endopeptidase activity |  | 4.392
ACN-0186855 | putative: conserved unknown |  |  |  | 4.345
ACN-0183253 | putative: serine protease -!- questionable: [NAME] mori prophenoloxidase activating factor 3 | proteolysis | serine-type endopeptidase activity |  | 4.319
[NAME] | serine protease | proteolysis | serine-type endopeptidase activity |  | 3.622
ACN-0186097 | putative: chitinase | cuticle chitin catabolic process;signal transduction;cell-cell signaling | chitinase activity;hydrolase activity, hydrolyzing N-glycosyl compounds | extracellular region | 3.437
ACN-0180264 | questionable: acetyl-CoA carboxylase |  |  |  | 3.37
ACN-0186520 | unknown |  |  |  | 3.241
ACN-0186842 | putative: potassium:amino acid symporter | amino acid metabolic process;cation transport;neurotransmitter transport;extracellular transport;amino acid transport | neurotransmitter:sodium symporter activity;cation transporter activity;potassium:amino acid symporter activity | integral to plasma membrane | 3.026
ACN-0186435 | dimethylaniline monooxygenase (N-oxide-forming) | [NAME] acid metabolic process | monooxygenase activity;dimethylaniline monooxygenase (N-oxide-forming) activity;disulfide oxidoreductase activity | mitochondrion;microsome;cytosol | 2.802
ACN-0182842 | putative: conserved unknown |  |  |  | 2.791
ACN-0185106 | unknown |  |  |  | 2.687
ACN-0184442 | putative: serine carboxyprotease | proteolysis;defense response;melanization defense response;positive regulation of melanization defense response | serine carboxypeptidase activity;trypsin activity;serine-type peptidase activity;monophenol monooxygenase activator activity |  | 2.652
ACN-0185477 | [NAME] -!- putative: transferrin | iron ion transport;iron ion homeostasis;defense response | iron ion transporter activity;carrier activity;ferric iron binding | extracellular region | 2.583
[NAME] | cytosolic large ribosomal subunit L26 | translation | nucleic acid binding;structural constituent of ribosome | cytosolic large ribosomal subunit (sensu [NAME]) | 2.496
ACN-0187345 | questionable: conserved unknown |  |  |  | 2.48
ACN-0180550 | putative:serine protease |  |  |  | 2.47
ACN-0185796 | unknown |  |  |  | 2.466
ACN-0186845 | questionable: conserved unknown |  |  |  | 2.448
ACN-0182518 | questionable: chitin binding |  |  |  | 2.373
ACN-0187083 | conserved unknown |  |  |  | 2.362
[NAME] | questionable: pyrophosphatase |  |  |  | 2.304
ACN-0187670 | unknown |  |  |  | 2.263
ACN-0186633 | unknown |  |  |  | 2.204
ACN-0183021 | unknown |  |  |  | 2.194
ACN-0183516 | unknown |  |  |  | 2.188
ACN-0182555 | putative: protease inhibitor |  | endopeptidase inhibitor activity |  | 2.185
ACN-0181732 | putative: chromatin assembly factor 1 subunit | negative regulation of transcription from RNA polymerase II promoter;cytokinesis;DNA repair;nucleosome assembly;DNA replication-dependent nucleosome assembly;chromatin silencing;transcription;chorion gene amplification;histone methylation;histone acetylation;nucleosome spacing;nucleosome mobilization | chromatin binding;histone acetyltransferase binding;histone binding;histone deacetylase binding;histone lysine N-methyltransferase activity (H3-K9 specific);histone lysine N-methyltransferase activity (H3-K27 specific) | nucleus;transcription factor [NAME] assembly [NAME] remodeling complex;NURF complex;ACF complex;Myb complex;ESC/E(Z) complex | 2.163
ACN-0180383 | putative: conserved unknown |  |  |  | 2.151
ACN-0185423 | unknown |  |  |  | 2.149
ACN-0186112 | protein kinase C inhibitor |  |  |  | 2.144
ACN-0184789 | questionable: nucleic acid binding protein |  |  |  | 2.102
ACN-0181224 | putative: mucin-like peritrophin |  |  |  | 2.063
ACN-0187105 | questionable: DNA binding protein |  |  |  | 2.058
ACN-0182765 | putative: conserved unknown |  |  |  | 2.004
ACN-0184581 | 3-hydroxyisobutyrate dehydrogenase | pentose-phosphate shunt;amino acid metabolic process;valine metabolic process | phosphogluconate dehydrogenase (decarboxylating) activity;3-hydroxyisobutyrate dehydrogenase activity;NAD binding | mitochondrion | -2.09
ACN-0188001 | innexin-1 -!- gap-junction forming channel | signal transduction;nervous system development;phototransduction;visual behavior | gap-junction forming channel activity | gap junction;integral to membrane | -2.15
ACN-0187467 | unknown |  |  |  | -2.18
ACN-0180919 | questionable: DNA ligase (ATP) |  |  |  | -2.28
ACN-0181256 | unknown |  |  |  | -2.31
ACN-0187373 | unknown |  |  |  | -2.35
ACN-0181436 | carrier | coenzyme metabolic process;transport;prosthetic group metabolic process | carrier activity;retinal binding | intracellular | -2.4
ACN-0181835 | questionable: conserved unknown -!- conserved unknown |  |  |  | -2.4
ACN-0180196 | putative: vitellogenin-B |  |  |  | -2.51
ACN-0182097 | questionable: transcription regulator |  |  |  | -2.7
ACN-0184190 | questionable: insulin-like growth factor |  |  |  | -2.72
ACN-0185620 | unknown |  |  |  | -3.15
ACN-0186186 | vitellogenin |  |  |  | -3.21
ACN-0183777 | unknown |  |  |  | -3.7
ACN-0184664 | cytosolic large ribosomal subunit L27 | translation | nucleic acid binding;structural constituent of ribosome | cytosolic large ribosomal subunit (sensu [NAME]) | -4.31
ACN-0186094 | protein binding | [NAME] import into nucleus;anti-apoptosis;chromosome segregation;mitosis;anterior/posterior pattern formation | protein binding |  | -7.46
ACN-0184877 | putative: conserved unknown |  |  |  | -11
[NAME] | putative: conserved unknown |  |  |  | -11.88
ACN-0184811 | putative: N-glycosyl hydrolase | carbohydrate metabolic process | glucosidase activity;hydrolase activity, hydrolyzing N-glycosyl compounds |  | -14.71
ACN-0187663 | lamin | cytoskeleton organization and biogenesis;mitotic nuclear envelope reassembly | structural constituent of cytoskeleton | lamin filament | -14.75
ACN-0183609 | conserved unknown |  |  |  | -17.04
ACN-0187095 | unknown |  |  |  | -19.61
ACN-0182568 | putative: carrier | transport | carrier activity;binding | mitochondrial envelope;mitochondrial inner membrane | -20
ACN-0187472 | unknown |  |  |  | -20.83
ACN-0184868 | questionable: conserved unknown |  |  |  | -33.78
6 Hour
[NAME] | questionable: conserved unknown |  |  |  | 25.5
ACN-0185532 | questionable: keratin |  |  |  | 17.01
ACN-0186385 | putative: conserved unknown |  |  |  | 13.52
ACN-0181041 | putative: glycine-rich secreted salivary peptide |  |  |  | 13.2
ACN-0180573 | unknown |  |  |  | 12.75
ACN-0185889 | unknown |  |  |  | 12.69
ACN-0182548 | questionable: conserved unknown |  |  |  | 12.12
ACN-0182511 | unknown |  |  |  | 10.72
ACN-0182427 | unknown |  |  |  | 8.991
ACN-0181082 | putative: conserved unknown |  |  |  | 7.352
ACN-0186855 | putative: conserved unknown |  |  |  | 6.188
ACN-0181325 | serine protease | proteolysis | serine-type endopeptidase activity |  | 5.913
ACN-0182295 | questionable: conserved unknown |  |  |  | 5.443
ACN-0187011 | questionable: keratin 10 |  |  |  | 5.141
ACN-0185369 | questionable: conserved unknown |  |  |  | 4.796
ACN-0187239 | putative: conserved unknown |  |  |  | 4.765
ACN-0183253 | putative: serine protease -!- questionable: [NAME] mori prophenoloxidase activating factor 3 | proteolysis | serine-type endopeptidase activity |  | 4.438
ACN-0184331 | unknown |  |  |  | 4.361
ACN-0183955 | unknown |  |  |  | 3.976
ACN-0183999 | unknown |  |  |  | 3.881
ACN-0184394 | putative: serine protease | proteolysis | trypsin activity;monophenol monooxygenase activator activity |  | 3.666
ACN-0181343 | questionable: monophenol monooxygenase activator |  |  |  | 3.647
ACN-0183920 | unknown |  |  |  | 3.609
ACN-0186842 | putative: potassium:amino acid symporter | amino acid metabolic process;cation transport;neurotransmitter transport;extracellular transport;amino acid transport | neurotransmitter:sodium symporter activity;cation transporter activity;potassium:amino acid symporter activity | integral to plasma membrane | 3.601
ACN-0184442 | putative: serine carboxyprotease | proteolysis;defense response;melanization defense response;positive regulation of melanization defense response | serine carboxypeptidase activity;trypsin activity;serine-type peptidase activity;monophenol monooxygenase activator activity |  | 3.514
ACN-0180530 | putative: cecropin | antibacterial humoral response (sensu Protostomia);defense response to bacterium;defense response to Gram-negative bacterium;defense response to Gram-positive bacterium;defense response to fungus |  | extracellular region | 3.433
[NAME] | serine protease | proteolysis | serine-type endopeptidase activity |  | 3.397
ACN-0186260 | conserved unknown |  |  |  | 3.261
ACN-0181029 | unknown |  |  |  | 3.224
ACN-0180264 | questionable: acetyl-CoA carboxylase |  |  |  | 3.211
ACN-0186097 | putative: chitinase | cuticle chitin catabolic process;signal transduction;cell-cell signaling | chitinase activity;hydrolase activity, hydrolyzing N-glycosyl compounds | extracellular region | 3.047
ACN-0183113 | unknown |  |  |  | 3.014
ACN-0185734 | unknown |  |  |  | 2.891
[NAME] | endonuclease G | DNA-dependent DNA replication;apoptotic program | nucleic acid binding;endodeoxyribonuclease activity | mitochondrion;mitochondrial inner membrane | 2.817
ACN-0183865 | unknown |  |  |  | 2.796
ACN-0185451 | chromosome segregation in cell cycle | cell cycle;chromosome segregation;mitotic checkpoint;mitotic spindle checkpoint |  | kinetochore;nucleus;nuclear envelope;cytoplasm;kinetochore microtubule | 2.769
ACN-0185838 | unknown |  |  |  | 2.768
ACN-0186540 | phosphomannomutase | monosaccharide metabolic process | phosphomannomutase activity |  | 2.747
ACN-0182451 | histone deacetylase | histone deacetylation | histone deacetylase activity | histone deacetylase complex | 2.746
ACN-0180268 | putative: conserved unknown |  |  |  | 2.692
ACN-0188039 | conserved unknown |  |  |  | 2.603
ACN-0186585 | unknown product |  |  |  | 2.584
ACN-0181224 | putative: mucin-like peritrophin |  |  |  | 2.577
ACN-0186413 | questionable: conserved unknown |  |  |  | 2.527
ACN-0182842 | putative: conserved unknown |  |  |  | 2.517
ACN-0187256 | peptidoglycan recognition protein LE | defense response;immune response;signal transduction;peptidoglycan catabolic process;response to bacterium;defense response to Gram-positive bacterium | receptor [NAME] amidase activity;peptidoglycan receptor activity;peptidoglycan binding | extracellular region;integral to plasma membrane | 2.513
ACN-0184272 | putative: [NAME] binding -!- [NAME] binding |  | nucleotide binding;mRNA binding |  | 2.452
ACN-0185878 | unknown |  |  |  | 2.44
ACN-0181973 | conserved unknown | defense response;defense response to bacterium | receptor binding |  | 2.435
ACN-0185874 | unknown |  |  |  | 2.317
ACN-0187869 | putative: conserved unknown | ciliary or flagellar motility;muscle contraction;calcium-mediated signaling | calcium ion [NAME] binding | flagellin-based flagellum | 2.278
ACN-0184588 | questionable: conserved unknown |  |  |  | 2.26
ACN-0180210 | questionable: conserved unknown |  |  |  | 2.237
ACN-0181327 | ligand-dependent nuclear receptor | regulation of transcription from RNA polymerase II promoter;lipid metabolic process;signal transduction;border follicle cell migration (sensu Insecta);metamorphosis;neuron remodeling;ecdysone-mediated induction of salivary gland cell autophagic cell death;regulation of development, heterochronic;negative regulation of cell differentiation;negative regulation of transcription, DNA-dependent;positive regulation of transcription;dendrite morphogenesis | DNA binding;transcription factor activity;ligand-dependent nuclear receptor activity;ecdysteroid hormone receptor activity;juvenile hormone binding;protein binding;zinc ion binding;sequence-specific DNA binding | [NAME] receptor [NAME] | 2.236
ACN-0185938 | putative: actin binding | cytoskeletal anchoring;signal transduction;ectoderm development;nervous system development | actin binding;receptor binding;structural constituent of cytoskeleton;cytoskeletal protein binding | plasma membrane | 2.205
ACN-0181464 | questionable: conserved unknown |  |  |  | 2.106
ACN-0184161 | unknown |  |  |  | 2.079
ACN-0181839 | unknown |  |  |  | 2.079
ACN-0185154 | unknown |  |  |  | 2.078
ACN-0187517 | DNA-directed RNA polymerase | transcription from RNA polymerase III promoter;tRNA metabolic process;rRNA metabolic process | nucleic acid binding;DNA binding;DNA-directed RNA polymerase activity | nucleus;DNA-directed RNA polymerase III complex | 2.075
ACN-0186997 | unknown |  |  |  | 2.054
ACN-0184171 | [NAME] serine protease | proteolysis | serine-type endopeptidase activity |  | 2.053
ACN-0185411 | unknown |  |  |  | 2.04
ACN-0182272 | wide-spectrum protease inhibitor | antibacterial humoral response (sensu Protostomia) | serine-type endopeptidase inhibitor activity;wide-spectrum protease inhibitor activity |  | 2.019
ACN-0183258 | cytochrome oxidase subunit 3 |  |  |  | 2.002
ACN-0187643 | questionable: D-aspartate oxidase |  |  |  | -2.01
ACN-0185109 | conserved unknown | amino acid transport;regulation of growth | amino acid-polyamine transporter activity;amino acid transporter activity | membrane | -2.02
ACN-0184166 | 3-oxoacid CoA-transferase | fatty acid metabolic process;ketone body catabolic process | 3-oxoacid CoA-transferase activity | mitochondrial matrix | -2.03
ACN-0182985 | protein transporter | SRP-dependent cotranslational protein targeting to membrane, translocation;cell death;protein secretion | protein transporter [NAME] translocase activity | translocon complex | -2.06
ACN-0184427 | unknown |  |  |  | -2.08
ACN-0184581 | 3-hydroxyisobutyrate dehydrogenase | pentose-phosphate shunt;amino acid metabolic process;valine metabolic process | phosphogluconate dehydrogenase (decarboxylating) activity;3-hydroxyisobutyrate dehydrogenase activity;NAD binding | mitochondrion | -2.09
PAH |  |  |  |  | -2.09
ACN-0187875 | methylenetetrahydrofolate dehydrogenase (NADP+) | amino acid biosynthetic process;folic acid and derivative biosynthetic process | formate-tetrahydrofolate ligase activity;methenyltetrahydrofolate cyclohydrolase activity;methylenetetrahydrofolate dehydrogenase (NADP+) activity;ATP binding |  | -2.1
ACN-0183287 | Fructose-1,6-bisphosphatase | carbohydrate metabolic process | fructose-bisphosphatase activity |  | -2.15
ACN-0182106 | unknown |  |  |  | -2.2
ACN-0187001 | mitochondrial large ribosomal subunit L3 | translation | nucleic acid binding;structural constituent of ribosome | mitochondrial large ribosomal subunit;mitochondrial small ribosomal subunit | -2.22
ACN-0180353 | phosphoribosylformylglycinamidine cyclo-ligase | purine base metabolic process;'de novo' IMP biosynthetic process;purine base biosynthetic process | phosphoribosylamine-glycine ligase activity;phosphoribosylformylglycinamidine cyclo-ligase activity;phosphoribosylglycinamide formyltransferase activity;ATP binding;hydrolase activity | cytoplasm | -2.23
ACN-0184278 | aldehyde dehydrogenase | pyruvate metabolic process;amino acid catabolic process | aldehyde dehydrogenase (NAD) activity | mitochondrion;mitochondrial matrix | -2.24
ACN-0182995 | receptor signaling protein | intracellular protein transport | receptor signaling protein activity;calcium ion binding | endoplasmic reticulum | -2.24
ACN-0187479 | dolichyl-phosphate beta-glucosyltransferase | carbohydrate metabolic process;protein amino acid glycosylation | dolichyl-phosphate beta-glucosyltransferase activity |  | -2.29
ACN-0183409 | RNA-binding | carbohydrate metabolic process;biosynthetic process | mRNA binding;serine-type endopeptidase activity;receptor activity;lyase activity;strictosidine synthase activity | cell surface;membrane | -2.33
ACN-0184599 | putative: protein transporter | SRP-dependent cotranslational protein targeting to membrane, translocation;cell death;protein secretion | protein transporter [NAME] translocase activity | translocon complex | -2.49
ACN-0187373 | unknown |  |  |  | -2.51
[NAME] | putative: carboxy-lyase | amino acid metabolic process;amino acid catabolic process | carboxy-lyase activity;isomerase activity |  | -2.54
ACN-0181261 | putative: oxidoreductase |  | oxidoreductase activity |  | -2.62
ACN-0184438 | conserved unknown | RNA localization;intracellular protein transport;exocytosis;membrane budding;larval cuticle biosynthetic process (sensu Insecta);larval cuticle pattern formation (sensu [NAME]) |  |  | -2.63
ACN-0185620 | unknown |  |  |  | -2.65
ACN-0181536 | putative: endoribonuclease | RNA catabolic process | nucleic acid binding;endoribonuclease activity;ribonuclease activity |  | -2.71
ACN-0184810 | unknown |  |  |  | -2.75
ACN-0180243 | 4-hydroxyphenylpyruvate dioxygenase | amino acid catabolic process;aromatic amino acid family metabolic process | 4-hydroxyphenylpyruvate dioxygenase activity |  | -3.1
ACN-0185441 | unknown |  |  |  | -3.33
ACN-0183361 | triacylglycerol lipase | [NAME] process | triacylglycerol lipase activity |  | -3.61
ACN-0181795 | branched chain keto acid dehydrogenase E1, alpha polypeptide -!- 3-methyl-2-oxobutanoate dehydrogenase | amino acid catabolic process;acyl-CoA biosynthetic process | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity | 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex | -4.26
ACN-0186186 | vitellogenin |  |  |  | -5.1
[NAME] | putative: sarcosine dehydrogenase | [NAME] acid metabolic process;glycine catabolic process | aminomethyltransferase activity;sarcosine dehydrogenase activity | cytoplasm | -6.21
ACN-0186915 | G protein-coupled receptor kinase | protein amino acid phosphorylation;signal transduction | protein serine/threonine kinase activity;AMP-activated protein kinase activity;receptor signaling protein serine/threonine kinase activity;G-protein coupled receptor kinase activity;ATP binding | [NAME] protein kinase complex | -7.09
ACN-0180944 | unknown |  |  |  | -7.87
ACN-0187872 | putative: conserved unknown |  |  |  | -8.85
ACN-0180633 | putative: conserved unknown |  |  |  | -12.14
ACN-0181169 | unknown |  |  |  | -12.45
ACN-0180295 | unknown |  |  |  | -17.15
ACN-0185390 | questionable: kinase regulator |  |  |  | -46.73
ACN-0183679 | unknown |  |  |  | -49.02
12 Hour
ACN-0185889 | unknown |  |  |  | 17.85
ACN-0185532 | questionable: keratin |  |  |  | 13.56
ACN-0187011 | questionable: keratin 10 |  |  |  | 6.711
ACN-0184442 | putative: serine carboxyprotease | proteolysis;defense response;melanization defense response;positive regulation of melanization defense response | serine carboxypeptidase activity;trypsin activity;serine-type peptidase activity;monophenol monooxygenase activator activity |  | 6.173
ACN-0187239 | putative: conserved unknown |  |  |  | 5.065
ACN-0186510 | questionable: conserved unknown |  |  |  | 4.45
ACN-0186097 | putative: chitinase | cuticle chitin catabolic process;signal transduction;cell-cell signaling | chitinase activity;hydrolase activity, hydrolyzing N-glycosyl compounds | extracellular region | 4.162
ACN-0183115 | [NAME] membrane protein |  |  |  | 4.081
ACN-0180264 | questionable: acetyl-CoA carboxylase |  |  |  | 3.959
ACN-0183253 | putative: serine protease -!- questionable: [NAME] mori prophenoloxidase activating factor 3 | proteolysis | serine-type endopeptidase activity |  | 3.891
ACN-0185796 | unknown |  |  |  | 3.509
ACN-0184350 | unknown product |  |  |  | 3.412
ACN-0181325 | serine protease | proteolysis | serine-type endopeptidase activity |  | 3.207
ACN-0183920 | unknown |  |  |  | 3.148
ACN-0185612 | serine protease |  |  |  | 3.123
ACN-0183119 | unknown |  |  |  | 3.105
ACN-0186593 | unknown |  |  |  | 2.943
ACN-0186082 | questionable: conserved unknown |  |  |  | 2.939
ACN-0184428 | conserved unknown |  |  |  | 2.841
ACN-0185551 | serine protease | proteolysis | serine-type endopeptidase activity |  | 2.839
ACN-0183545 | questionable: c-type lectin |  |  |  | 2.823
[NAME] | unknown |  |  |  | 2.718
ACN-0185874 | unknown |  |  |  | 2.674
ACN-0187198 | unknown |  |  |  | 2.646
ACN-0181965 | unknown |  |  |  | 2.626
ACN-0186385 | putative: conserved unknown |  |  |  | 2.585
ACN-0186540 | phosphomannomutase | monosaccharide metabolic process | phosphomannomutase activity |  | 2.527
ACN-0185734 | unknown |  |  |  | 2.505
ACN-0180814 | conserved unknown |  |  |  | 2.419
ACN-0185477 | [NAME] -!- putative: transferrin | iron ion transport;iron ion homeostasis;defense response | iron ion transporter activity;carrier activity;ferric iron binding | extracellular region | 2.281
[NAME] | questionable: conserved unknown |  |  |  | 2.2
ACN-0186260 | conserved unknown |  |  |  | 2.19
ACN-0186612 | oxidoreductase | metabolic process | oxidoreductase activity |  | 2.173
ACN-0182727 | farnesoic acid O methyltransferase |  | farnesoic acid O-methyltransferase activity |  | 2.147
ACN-0185578 | unknown |  |  |  | 2.066
ACN-0182518 | questionable: chitin binding |  |  |  | 2.06
ACN-0182300 | unknown |  |  |  | 2.057
ACN-0184325 | putative: serine protease | proteolysis;maternal determination of dorsal/ventral axis, [NAME], germ-line encoded;Toll signaling [NAME]/ventral axis [NAME] processing | serine-type endopeptidase activity;trypsin activity;peptidase activity;serine-type peptidase activity | extracellular region | 2.026
ACN-0182783 | unknown |  |  |  | 2.011
ACN-0181295 | questionable: chitin binding |  |  |  | 2.005
ACN-0184400 | unknown |  |  |  | 2.005
ACN-0182874 | questionable: conserved unknown |  |  |  | -2.02
ACN-0187930 | trehalose phosphatase | disaccharide metabolic process;trehalose biosynthetic process | trehalose-phosphatase activity |  | -2.03
ACN-0183942 | unknown |  |  |  | -2.04
ACN-0185953 | unknown |  |  |  | -2.05
ACN-0187338 | putative: pigment cell dehydrogenase reductase | [NAME] process | alcohol dehydrogenase activity |  | -2.09
ACN-0183976 | [NAME] | proteolysis;salivary gland cell autophagic cell death;autophagic cell death;regulation of catalytic activity | cathepsin B activity |  | -2.11
ACN-0181741 | small ribonucleoprotein [NAME] | nuclear mRNA splicing, via spliceosome;central nervous system development;peripheral nervous system development;muscle development;neuron differentiation;lymph gland development ([NAME]) |  | nucleus;spliceosome;small nuclear ribonucleoprotein complex | -2.13
ACN-0181711 | unknown |  |  |  | -2.21
ACN-0183944 | questionable: conserved unknown |  |  |  | -2.21
ACN-0185679 | putative: guanyl-nucleotide exchange factor | intracellular signaling cascade;ectoderm development;nervous system development | guanyl-nucleotide exchange factor activity;receptor binding;diacylglycerol binding |  | -2.22
ACN-0186622 | [NAME] epoxide hydrolase | [NAME] process;defense response;response to toxin | epoxide hydrolase activity;juvenile hormone epoxide hydrolase activity | microsome;membrane | -2.23
ACN-0187069 | dynamin associated | intracellular protein transport;receptor-mediated endocytosis;neurotransmitter secretion;protein localization;synaptic vesicle endocytosis;synaptic growth at neuromuscular junction | calcium ion binding;protein binding | presynaptic membrane | -2.24
ACN-0185437 | questionable: N-glycosyl hydrolase |  |  |  | -2.25
ACN-0186509 | unknown |  |  |  | -2.5
ACN-0186640 | cysteine protease | proteolysis | cysteine-type endopeptidase activity |  | -2.58
ACN-0186227 | questionable: conserved unknown |  |  |  | -2.7
ACN-0183192 | unknown |  |  |  | -2.75
ACN-0185677 | unknown |  |  |  | -2.78
ACN-0185386 | conserved unknown |  |  |  | -3.25
ACN-0181396 | unknown |  |  |  | -3.26
ACN-0187057 | questionable: conserved unknown |  |  |  | -3.72
ACN-0180723 | questionable: conserved unknown |  |  |  | -4.93
ACN-0183601 | putative: cell proliferation component | cell proliferation |  |  | -5.38
ACN-0183717 | unknown |  |  |  | -5.43
ACN-0183196 | unknown |  |  |  | -5.92
ACN-0183632 | histone-arginine N-methyltransferase | protein amino acid methylation;histone methylation;peptidyl-arginine methylation, to asymmetrical-dimethyl arginine;induction of programmed cell death by ecdysone | histone-arginine N-methyltransferase activity;protein-arginine N-methyltransferase activity;protein-arginine omega-N monomethyltransferase activity;protein-arginine omega-N asymmetric methyltransferase activity;histone methyltransferase activity | histone methyltransferase complex | -11.34
ACN-0186279 | thioredoxin peroxidase | oxygen and reactive oxygen species metabolic process;apoptosis;induction of apoptosis;defense response | peroxidase activity;thioredoxin peroxidase activity;antioxidant activity | extracellular region | -11.45
ACN-0185708 | putative: conserved unknown |  |  |  | -12.87
ACN-0183249 | unknown |  |  |  | -14.95
ACN-0180722 | unknown |  |  |  | -15.92
ACN-0182774 | putative: ATP-dependent RNA helicase | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | mRNA binding;ATP-dependent RNA helicase activity;ATP binding |  | -22.17
ACN-0186359 | conserved unknown -!- putative: protein phosphatase regulator | protein amino acid dephosphorylation | protein serine/threonine phosphatase activity;binding;protein phosphatase type 2A regulator activity | protein phosphatase type 2A [NAME] serine/threonine phosphatase complex | -29.24
ACN-0187872 | putative: conserved unknown |  |  |  | -32.87
ACN-0183765 | questionable: conserved unknown |  |  |  | -43.48
ACN-0180241 | questionable: transcription regulator |  |  |  | -51.55
24 Hour
ACN-0185532 | questionable: keratin |  |  |  | 10.25
ACN-0185889 | unknown |  |  |  | 5.017
ACN-0180341 | putative: cecropin A |  |  |  | 4.608
ACN-0187011 | questionable: keratin 10 |  |  |  | 3.916
ACN-0180530 | putative: cecropin | antibacterial humoral response (sensu Protostomia);defense response to bacterium;defense response to Gram-negative bacterium;defense response to Gram-positive bacterium;defense response to fungus |  | extracellular region | 3.664
ACN-0186510 | questionable: conserved unknown |  |  |  | 3.546
ACN-0183955 | unknown |  |  |  | 3.539
ACN-0186800 | questionable: conserved unknown |  |  |  | 3.176
ACN-0182054 | lysozyme |  |  |  | 3.133
ACN-0183044 | questionable: conserved unknown |  |  |  | 3.132
ACN-0183243 | conserved unknown |  |  |  | 3.08
ACN-0180447 | unknown |  |  |  | 2.911
ACN-0183908 | glutamyl-tRNA(Gln) amidotransferase | glutaminyl-tRNA aminoacylation;amino acid metabolic process | glutamyl-tRNA(Gln) amidotransferase activity | mitochondrion | 2.868
ACN-0183920 | unknown |  |  |  | 2.831
ACN-0186385 | putative: conserved unknown |  |  |  | 2.675
ACN-0186082 | questionable: conserved unknown |  |  |  | 2.674
ACN-0182914 | questionable: holotricin 3 |  |  |  | 2.566
ACN-0181161 | unknown |  |  |  | 2.492
[NAME] | questionable: conserved unknown |  |  |  | 2.477
ACN-0183253 | putative: serine protease -!- questionable: [NAME] mori prophenoloxidase activating factor 3 | proteolysis | serine-type endopeptidase activity |  | 2.412
ACN-0184331 | unknown |  |  |  | 2.404
ACN-0184046 | unknown |  |  |  | 2.383
ACN-0185767 | questionable: conserved unknown |  |  |  | 2.371
ACN-0182300 | unknown |  |  |  | 2.348
ACN-0184455 | ubiquinol-cytochrome-c reductase | mitochondrial electron transport, ubiquinol to cytochrome c | ubiquinol-cytochrome-c reductase activity;ubiquinone binding | mitochondrial respiratory chain complex III | 2.345
ACN-0182523 | unknown |  |  |  | 2.312
ACN-0185612 | serine protease |  |  |  | 2.294
ACN-0182159 | questionable: actin binding protein |  |  |  | 2.276
ACN-0182376 | questionable: transmembrane receptor protein serine/threonine kinase |  |  |  | 2.269
ACN-0186274 | unknown |  |  |  | 2.243
ACN-0180850 | [NAME] |  |  |  | 2.237
ACN-0186389 | questionable: conserved unknown |  |  |  | 2.233
ACN-0186097 | putative: chitinase | cuticle chitin catabolic process;signal transduction;cell-cell signaling | chitinase activity;hydrolase activity, hydrolyzing N-glycosyl compounds | extracellular region | 2.199
ACN-0187345 | questionable: conserved unknown |  |  |  | 2.17
ACN-0184233 | questionable: chitin binding protein |  |  |  | 2.105
[NAME] | serine protease | proteolysis | serine-type endopeptidase activity |  | 2.085
ACN-0186845 | questionable: conserved unknown |  |  |  | 2.066
ACN-0181002 | [NAME] | cytoskeleton organization and biogenesis;phosphoenolpyruvate-dependent sugar phosphotransferase system | actin binding;structural constituent of cytoskeleton;sugar porter activity | extracellular region;cytosol;actin filament | 2.057
ACN-0181325 | serine protease | proteolysis | serine-type endopeptidase activity |  | 2.056
[NAME] | questionable: conserved unknown |  |  |  | 2.052
ACN-0185818 | unknown |  |  |  | 2.048
ACN-0185414 | unknown product |  |  |  | 2.026
ACN-0184720 | putative: conserved unknown |  |  |  | -2.16
ACN-0187443 | putative: development component | intracellular protein transport;multicellular organismal development |  |  | -2.21
ACN-0185269 | cytosolic large ribosomal subunit L40 | establishment and/or maintenance of chromatin architecture;regulation of transcription, DNA-dependent;translation;protein modification;ATP-dependent proteolysis;ubiquitin-dependent protein catabolic process;ubiquitin cycle;response to stress | nucleic acid binding;structural constituent of [NAME] binding | nucleus;cytoplasm;ribosome;cytosolic large ribosomal subunit (sensu [NAME]) | -2.26
ACN-0183803 | questionable: conserved unknown |  |  |  | -2.39
ACN-0185695 | [NAME] | protein amino acid phosphorylation;fatty acid metabolic process;response to stress;defense response;intracellular signaling cascade;regulation of phosphate metabolic process;cholesterol homeostasis | protein serine/threonine kinase activity;AMP-activated protein kinase activity;receptor signaling protein serine/threonine kinase activity |  | -2.58
ACN-0184471 | unknown |  |  |  | -3.04
ACN-0187090 | unknown |  |  |  | -3.61
ACN-0182041 | conserved unknown |  |  |  | -4.59
ACN-0180774 | unknown |  |  |  | -10.68
ACN-0183791 | unknown |  |  |  | -13.7
ACN-0185232 | questionable: conserved unknown |  |  |  | -15.65
ACN-0185659 | unknown |  |  |  | -43.86
2-3 Days
ACN-0182132 | unknown |  |  |  | 4.637
ACN-0183153 | putative: conserved unknown |  |  |  | 3.144
ACN-0185574 | unknown |  |  |  | 2.446
ACN-0186547 | conserved unknown |  |  | mediator complex | 2.039
ACN-0185602 | putative: odorant-binding |  |  |  | -2.14
5-6 Days
ACN-0180301 | questionable: sugar binding protein |  |  |  | 2.754
ACN-0186293 | questionable: protein phosphatase |  |  |  | 2.376
ACN-0186541 | heat shock cognate 70-3 (Hsc70-3) | protein folding;protein complex assembly;defense response;response to heat;sleep | ATP binding;ATPase activity | endoplasmic reticulum | 36.1
8-9 Days
ACN-0180672 | putative: zinc ion binding | protein monoubiquitination;apoptosis;anti-apoptosis;multicellular organismal development;spermatid nuclear differentiation;border follicle cell migration (sensu Insecta);sensory organ development;germ cell migration;protein ubiquitination during ubiquitin-dependent protein catabolic process;negative regulation of apoptosis;negative regulation of caspase activity;antennal morphogenesis | ubiquitin-protein ligase activity;protein binding;zinc ion binding |  | 6.269
ACN-0186414 | Proteasome 25kD subunit endopeptidase | ATP-dependent proteolysis;ubiquitin-dependent protein catabolic process | endopeptidase activity;threonine endopeptidase activity | proteasome complex (sensu Eukaryota);proteasome core complex (sensu [NAME]) | 3.641
ACN-0186289 | questionable: tropomyosin |  |  |  | 3.557
ACN-0185612 | serine protease |  |  |  | 3.461
[NAME] | unknown |  |  |  | 3.265
ACN-0180854 | questionable: conserved unknown |  |  |  | 3.078
ACN-0186497 | NADH dehydrogenase |  |  |  | 2.975
ACN-0186544 | unknown |  |  |  | 2.881
ACN-0187293 | translation initiation factor 2 gamma -!- histone methyltransferase | DNA methylation;establishment and/or maintenance of chromatin architecture;chromatin assembly or disassembly;chromatin silencing;chromatin silencing at telomere;translational initiation;oogenesis (sensu [NAME] silencing;histone modification;histone methylation;chromatin silencing at centromere;histone H3-K9 methylation | tRNA binding;chromatin binding;translation initiation factor activity;GTP binding;zinc ion binding;histone methyltransferase activity;histone lysine N-methyltransferase activity (H3-K9 specific) | chromosome, pericentric region;heterochromatin;nucleus;cytosol;eukaryotic translation initiation factor 2 complex | 2.87
ACN-0186418 | putative: conserved unknown |  |  |  | 2.761
ACN-0186622 | [NAME] epoxide hydrolase | [NAME] process;defense response;response to toxin | epoxide hydrolase activity;juvenile hormone epoxide hydrolase activity | microsome;membrane | 2.508
ACN-0185364 | [NAME] | [NAME] adhesion |  | plasma membrane | 2.071
13-14 Days
ACN-0186599 | unknown |  |  |  | -2.07
ACN-0180660 | questionable: patched binding protein |  |  |  | -20.88