Spreadsheet: 461ea28f-e559-49d2-b3dc-54b8d9d1123b
Sheet: Sheet1

Question 4: Which Treatments And Interventions Will Help? (Treatments) | Fiscal Year: 2010 | 277 projects | 68123890.33 | Unnamed: 4
4SA. Support at least three randomized controlled trials that address co-occurring medical conditions associated with ASD by 2010. IACC Recommended Budget: $13,400,000 over 3 years. | yellow | 4 projects | 3787700
Project Title | Funder | Principal Investigator | Institution | Funding
Treatment of sleep problems in children with autism spectrum disorder with melatonin: A double-blind, placebo-controlled study | National Institutes of Health | Hopkins, Bobbi | Baylor College of Medicine | 8775
Autism Intervention Research Network on Physical Health (AIR-P network) | Health Resources and Services Administration | Perrin, [NAME] | Massachusetts General Hospital | 3651425
Cognitive-behavioral group treatment for anxiety symptoms in adolescents with high-functioning autism spectrum disorders | Autism Speaks | [NAME], [NAME] | University of Colorado Denver | 0
Treatment of sleep problems in children with autism spectrum disorder with melatonin: A double-blind, placebo-controlled study | Autism Speaks | Hopkins, Bobbi | Baylor College of Medicine | 127500
4SB. Standardize and validate at least 20 model systems (e.g., cellular and/or animal) that replicate features of ASD and will allow identification of specific molecular targets or neural circuits amenable to existing or new interventions by 2012. IACC Recommended Budget: $75,000,000 over 5 years. | green | 92 projects | 23229501.04
Project Title | Funder | Principal Investigator | Institution | Funding
A mouse knock-in model for ENGRAILED 2 autism susceptibility | National Institutes of Health | Millonig, [NAME] | University of Medicine & Dentistry of New Jersey | 227135
Animal model of speech sound processing in autism | National Institutes of Health | Kilgard, [NAME] | University of Texas at Dallas | 325125
Animal models of neuropsychiatric disorders | National Institutes of Health | Crawley, [NAME] | National Institutes of Health | 1769941
Autism iPSCs for studying function and dysfunction in human neural development | National Institutes of Health | Loring, [NAME] | The Scripps Research Institute | 254152
Role of L-type calcium channels in hippocampal neuronal network activity | National Institutes of Health | Owen, [NAME] | Stanford University | 32741
Evaluation of altered fatty acid metabolism via gas chromatography/mass spectroscopy and time-of-flight secondary ion mass spectroscopy imaging in the propionic acid rat model of autism spectrum disorders | Autism Research Institute | MacFabe, [NAME] | University of Western Ontario | 25000
Neurobiology of mouse models for human chr 16p11.2 microdeletion and fragile X | National Institutes of Health | Bear, [NAME] | Massachusetts Institute of Technology | 210000
Micro-RNA regulation in pluripotent stem cells | National Institutes of Health | Schatten, [NAME] | Southwest Foundation For Biomedical Research | 19189
Murine genetic models of autism | National Institutes of Health | Veenstra-Vanderweele, [NAME] | Vanderbilt University | 172389
Neurobiology of sociability in a mouse model system relevant to autism | National Institutes of Health | Brodkin, [NAME] | University of Pennsylvania | 354375
Basal ganglia circuitry and molecules in pathogenesis of motor stereotypy | National Institutes of Health | [NAME], Xiangdong | University of California, Los Angeles | 387767
Cellular and genetic correlates of increased head size in autism spectrum disorder | National Institutes of Health | Vaccarino, [NAME] | Yale University | 282901
Central vasopressin receptors and affiliation | National Institutes of Health | Young, [NAME] | Emory University | 32896
Genetic models of serotonin transporter regulation linked to mental disorders | National Institutes of Health | Ramamoorthy, Sammanda | Medical University of South Carolina | 184375
High content screens of neuronal development for autism research | National Institutes of Health | Halpain, Shelley | University of California, San Diego | 210977
High-resolution diffusion tensor imaging in mouse models relevant to autism | National Institutes of Health | Poptani, Harish | University of Pennsylvania | 199724
Transgenic mouse model to address heterogeneity in autism spectrum disorders | National Institutes of Health | Blakely, [NAME] | Vanderbilt University | 468586
Using induced pluripotent stem cells to identify cellular phenotypes of autism | National Institutes of Health | [NAME], Ricardo | Stanford University | 800000
Identifying genetic modifiers of rett syndrome in the mouse | Autism Science Foundation | Buchovecky, Christine | Baylor College of Medicine | 30000
Identifying impairments in synaptic connectivity in mouse models of ASD | Autism Science Foundation | Speed, Haley | University of Texas Southwestern Medical Center | 40000
A preclinical model for determining the role of AVPR1A in autism spectrum disorders | Autism Science Foundation | [NAME] | Mount Sinai School of Medicine | 0
Novel probiotic therapies for autism | Department of Defense | [NAME], [NAME] | California Institute of Technology | 570145
Central vasopressin receptors and affiliation | National Institutes of Health | Young, [NAME] | Emory University | 364425
Neuroligin function in vivo: Implications for autism and mental retardation | National Institutes of Health | [NAME], [NAME] | University of Texas Southwestern Medical Center | 392500
Novel genetic animal models of autism | National Institutes of Health | [NAME], [NAME] | University of Texas Southwestern Medical Center | 274750
Optimization of methods for production of both ICSI- and SCNT derived baboon embryonic stem cells | National Institutes of Health | Schatten, [NAME] | Southwest Foundation For Biomedical Research | 260102
Characterization of a novel mouse model of restricted repetitive behaviors | National Institutes of Health | Moy, Sheryl | University of North Carolina at Chapel Hill | 222000
Serotonin, autism, and investigating cell types for CNS disorders | National Institutes of Health | [NAME], [NAME] | The Rockefeller University | 90000
Identification of autism genes that regulate synaptic Nrx/Nlg signaling complexes | National Institutes of Health | Garner, [NAME] | Stanford University | 200000
Insight into MeCP2 function raises therapeutic possibilities for [NAME] syndrome | National Institutes of Health | Lomvardas, Stavros | University of California, San Francisco | 295298
Methods for production of ICSI and SCNT derived macaque stem cells | National Institutes of Health | Schatten, [NAME] | Southwest Foundation For Biomedical Research | 19188
Novel strategies to manipulate Ube3a expression for the treatment of autism and Angelman syndrome | Department of Defense | [NAME], [NAME] | University of North Carolina at Chapel Hill | 0
Preclinical testing of novel oxytocin receptor activators in models of autism phenotypes | Department of Defense | Moy, Sheryl | University of North Carolina at Chapel Hill | 167572
Preclinical testing of novel oxytocin receptor activators in models of autism phenotypes | Department of Defense | Pedersen, Cort | University of North Carolina at Chapel Hill | 39325
Preclinical testing of novel oxytocin receptor activators in models of autism phenotypes | Department of Defense | [NAME], [NAME] | University of North Carolina at Chapel Hill | 346289
Neurogenetic model of social behavior heterogeneity in autism spectrum disorders | National Institutes of Health | Platt, Michael | Duke University | 795188
Characterization of autism susceptibility genes on chromosome 15q11-13 | National Institutes of Health | Smith, Stephen | Beth Israel Deaconess Medical Center | 47606
Neurogenomics in a model for procedural learning | National Institutes of Health | Hilliard, [NAME] | University of California, Los Angeles | 33053
Serotonin, corpus callosum, and autism | National Institutes of Health | [NAME], [NAME] | University of Mississippi Medical Center | 303250
Characterization of the transcriptome in an emerging model for social behavior | National Institutes of Health | [NAME], [NAME] | Emory University | 426250
Cntnap2 in a behavioral model of autism | National Institutes of Health | White, [NAME] | University of California, Los Angeles | 262356
Synaptic deficits of iPS cell-derived neurons from patients with autism | National Institutes of Health | [NAME], [NAME] | Stanford University | 86588
Synaptic plasticity, memory and social behavior | National Institutes of Health | Chevere-Torres, [NAME] | New York University | 52154
Neural mechanisms of social cognition and bonding | National Institutes of Health | Young, [NAME] | Emory University | 43862
Neurobiological mechanism of 15q11-13 duplication autism spectrum disorder | National Institutes of Health | [NAME], [NAME] | Beth Israel Deaconess Medical Center | 304500
The genetic control of social behavior in the mouse | National Institutes of Health | Blanchard, [NAME] | University of Hawai'i at Manoa | 346000
Patient iPS cells with copy number variations to model neuropsychiatric disorders | National Institutes of Health | Ellis, [NAME] | The Hospital for Sick Children | 207388
Regulation of gene expression in the brain | National Institutes of Health | Young, [NAME] | National Institutes of Health | 2086763
Dissecting the neural control of social attachment | National Institutes of Health | Shah, Nirao | University of California, San Francisco | 772500
Dynamic regulation of Shank3 and ASD | National Institutes of Health | Worley, [NAME] | Johns Hopkins University | 300000
Exploring the neuronal phenotype of autism spectrum disorders using induced pluripotent stem cells | National Institutes of Health | Hallmayer, Joachim; [NAME], Ricardo | Stanford University | 241503
Modeling and pharmacologic treatment of autism spectrum disorders in Drosophila | Autism Speaks | McDonald, [NAME] | [NAME] of Medicine of Yeshiva University | 127500
Mouse genetic model of a dysregulated serotonin transporter variant associated with autism | Autism Speaks | Veenstra-Vanderweele, [NAME] | Vanderbilt University | 0
Neural mechanisms of social cognition and bonding | Autism Speaks | Young, [NAME] | Emory University | 0
[NAME] receptors and social attachment | National Institutes of Health | Young, [NAME] | Emory University | 121500
Development of a high-content neuronal assay to screen therapeutics for the treatment of cognitive dysfunction in autism spectrum disorders | Department of Defense | Bear, [NAME] | Massachusetts Institute of Technology | 0
Interaction between MEF2 and MECP2 in the pathogenesis of autism spectrum disorders - 1 | Department of Defense | Lipton, [NAME] | Burnham Institute | 0
Caspr2 dysfunction in autism spectrum disorders | Autism Speaks | Robbins, Elissa | Yale University | 0
Neuropharmacology of motivation and reinforcement in mouse models of autistic spectrum disorders | Autism Speaks | Malanga, C.J. | University of North Carolina School of Medicine | 0
NrCAM, a candidate susceptibility gene for visual processing deficits in autism | Autism Speaks | Maness, [NAME] | University of North Carolina at Chapel Hill | 0
A novel cell-based assay for autism research and drug discovery | Autism Speaks | [NAME], [NAME] | University of Arizona | 60000
The role of SHANK3 in the etiology of autism spectrum disorder | Autism Speaks | Bangash, [NAME] | Johns Hopkins University | 28000
Shank3 mutant characterization in vivo | Autism Speaks | Kouser, Mehreen | University of Texas Southwestern Medical Center | 28000
The genetics of restricted, repetitive behavior: An inbred mouse model | Autism Speaks | Lewis, Mark | University of Florida | 60000
Interaction between MEF2 and MECP2 in the pathogenesis of autism spectrum disorders -2 | Department of Defense | Nakanishi, Nobuki | Burnham Institute | 0
Analysis of cortical circuits related to ASD gene candidates | Autism Speaks | Zador, [NAME] | Cold Spring Harbor Laboratory | 0
Animal models of autism: Pathogenesis and treatment | Autism Speaks | [NAME], [NAME] | University of Texas Southwestern Medical Center | 84999
Deriving neuroprogenitor cells from peripheral blood of individuals with autism | Autism Speaks | Fujinami, [NAME] | University of Utah | 0
Functional study of synaptic scaffold protein SHANK3 and autism mouse model | Autism Speaks | Jiang, Yong-Hui | Duke University | 150000
Genomic resources for identifying genes regulating social behavior | Autism Speaks | Young, [NAME] | Emory University | 60000
Role of UBE3A in neocortical plasticity and function | Simons Foundation | Ehlers, [NAME] | Duke University | 490000
Small-molecule compounds for treating autism spectrum disorders | Simons Foundation | Philpot, [NAME] | The University of North Carolina at Chapel Hill | 175000
Synaptic and circuitry mechanisms of repetitive behaviors in autism | Simons Foundation | [NAME], Guoping | Massachusetts Institute of Technology | 400000
Investigation of the role of MET kinase in autism | Simons Foundation | [NAME], [NAME] | Johns Hopkins University School of Medicine | 366308.25
Mice lacking Shank postsynaptic scaffolds as an animal model of autism | Simons Foundation | [NAME], [NAME] | Massachusetts Institute of Technology | 128445
Neural and cognitive mechanisms of autism | Simons Foundation | Sur, Mriganka | Massachusetts Institute of Technology | 375000
Control of synaptic protein synthesis in the pathogenesis and therapy of autism | Simons Foundation | [NAME], [NAME] | Massachusetts General Hospital | 155062.5
Dissecting the circuitry basis of autistic-like behaviors in mice | Simons Foundation | [NAME], Guoping | Massachusetts Institute of Technology | 175000
Novel models to define the genetic basis of autism | Simons Foundation | Mills, [NAME] | Cold Spring Harbor Laboratory | 289633
Role of a novel Wnt pathway in autism spectrum disorders | Simons Foundation | [NAME], Louis | University of California, San Francisco | 750000
Using Drosophila to model the synaptic function of the autism-linked NHE9 | Simons Foundation | Littleton, [NAME] | Massachusetts Institute of Technology | 150000
Using iPS cells to study genetically defined forms with autism | Simons Foundation | [NAME], Ricardo | Stanford University | 200000
Systematic analysis of neural circuitry in mouse models of autism | Simons Foundation | Osten, Pavel | Cold Spring Harbor Laboratory | 149972.5
The role of SHANK3 in autism spectrum disorders | Simons Foundation | Buxbaum, [NAME] | Mount Sinai School of Medicine | 360000
16p11.2: defining the gene(s) responsible | Simons Foundation | Mills, [NAME] | Cold Spring Harbor Laboratory | 175000
Behavioral and physiological consequences of disrupted Met signaling | Simons Foundation | [NAME], Pat | University of Southern California | 800000
Using zebrafish and chemical screening to define function of autism genes | Simons Foundation | Sive, [NAME] | Whitehead Institute for Biomedical Research | 399999
Investigating the effects of chromosome 22q11.2 deletions | Simons Foundation | Karayiorgou, Maria | Columbia University | 150000
Function and dysfunction of neuroligins | Simons Foundation | Sudhof, [NAME] | Stanford University | 374382.79
Functional genomic dissection of language-related disorders | Simons Foundation | Fisher, [NAME] | University of Oxford | 235753
Genomic imbalances at the 22q11 locus and predisposition to autism | Simons Foundation | Gogos, [NAME] | Columbia University | 400000
Integrated approach to the neurobiology of autism spectrum disorders | Simons Foundation | Vaccarino, [NAME] | Yale University | 232118
4SC. Test safety and efficacy of at least five widely used interventions (e.g., nutrition, medications, assisted technologies, sensory integration, medical procedures) that have not been rigorously studied for use in ASD by 2012. IACC Recommended Budget: $27,800,000 over 5 years. | yellow | 18 projects | 1509745
Project Title | Funder | Principal Investigator | Institution | Funding
Folate rechallenge: A pilot study | National Institutes of Health | Beaudet, [NAME] | Baylor College of Medicine | 4578
Training outpatient clinicians to deliver cognitive behavior therapy to children | National Institutes of Health | [NAME], [NAME] | University of Colorado Denver | 208560
Probiotics and vitamin D in ASD | Autism Research Institute | Stubbs, Gene | Autism Research and Resources of Oregon (ARRO) | 45000
Feeding problems in children with ASD: Impact of parent education in modifying aberrant eating habits | Organization for Autism Research | Sharp, [NAME] | Marcus Institute | 9599
A randomized, double blind, placebo controlled study of fatty acid supplementation in autism | Autism Speaks | [NAME], [NAME] | Medical University of South Carolina | 0
The effects of a reciprocal questioning intervention on the reading comprehension and social communication of students with autism spectrum disorder | Organization for Autism Research | Whalon, [NAME] | The College of William and [NAME] | 10000
Writing instruction for children with autism spectrum disorders: A study of self-regulation and strategy use | Organization for Autism Research | Asaro-Saddler, Kristie | University at Albany, State University of New York | 20000
Effects of therapeutic horseback riding on children and adolescents with autism spectrum disorders | National Institutes of Health | [NAME], [NAME] | University of Colorado Denver | 305605
Evaluation of sensory integration treatment in ASD | National Institutes of Health | Camarata, Stephen; [NAME], [NAME] | Vanderbilt University | 345261
Treatment for autism | National Institutes of Health | [NAME], [NAME] | University of California, San Diego | 21228
Safety and efficacy of complementary and alternative medicine for autism spectrum disorders | Autism Speaks | [NAME], Stephen | University of California, San Francisco | 0
Intranasal oxytocin for the treatment of children and adolescents with autism spectrum disorders (ASD) | Department of Defense | Anagnostou, [NAME] | Holland Bloorview Kids Rehabilitation Hospital | 0
Double-blind placebo controlled trial of subcutaneous methyl B12 on behavioral and metabolic measures in children with autism | Autism Speaks | Hendren, [NAME] | University of California, [NAME] | 127500
Effectiveness of sensory based strategies for improving adaptive behaviors in children with autism | Autism Speaks | Schaaf, Roseann | [NAME] | 127414
Parents and professionals attitudes to dietary interventions in ASD (PADIA) | Autism Speaks | Le Couteur, [NAME] | Newcastle University | 0
Robotics and speech processing technology for the facilitation of social communication training in children with autism | Autism Speaks | Narayanan, Shrikanth | University of Southern California | 85000
Acupressure and acupuncture as an intervention with children with autism | Autism Speaks | Warren, [NAME] | Kennedy Krieger Institute | 0
Double masked placebo controlled trial of cholesterol in hypocholesterolemic ASD | Autism Speaks | Tierney, Elaine | Kennedy Krieger Institute | 200000
4SD. Complete two multi-site randomized controlled trials of comprehensive early intervention that address core symptoms, family functioning and community involvement by 2013. IACC Recommended Budget: $16,700,000 over 5 years. | green | 18 projects | 10306148
Project Title | Funder | Principal Investigator | Institution | Funding
A multi-site clinical randomized trial of the Hanen More Than Words Intervention | Autism Speaks | [NAME], [NAME] | University of Massachusetts Boston | 0
Intervention for infants at risk for autism | Autism Speaks | Rogers, [NAME] | University of California, [NAME] | 0
2/2-Effects of parent-implemented intervention for toddlers with autism spectrum disorder | National Institutes of Health | Lord, [NAME] | University of Michigan | 929381
Intervention for infants at risk for autism | Autism Speaks | Estes, Annette | University of Washington | 127500
Joint attention intervention for caregivers and their children with autism | Autism Speaks | Kasari, [NAME] | University of California, Los Angeles | 51000
Comparison of high to low intensity behavioral intervention | Center for Autism and Related Disorders | Granpeesheh, Doreen | Center for Autism and Related Disorders (CARD) | 121029
A randomized trial of the [NAME] curriculum for students with autism spectrum disorders in early elementary school classrooms | Department of Education | Wetherby, [NAME] | Florida State University | 749821
Comprehensive autism program using Strategies for Teaching based on Autism Research | Department of Education | Young, Helen | Portland State University | 729274
Efficacy and sustainability of the STAR program | Department of Education | Mandell, [NAME] | University of Pennsylvania | 758298
Leap - USA (Using Science-Based Approaches) | Department of Education | Strain, [NAME] | University of Colorado Denver | 0
Autism Intervention Research Network on Behavioral Health (AIR-B network) | Health Resources and Services Administration | Kasari, [NAME] | University of California, Los Angeles | 1989276
1/2-Effects of parent-implemented intervention for toddlers with autism spectrum disorder | National Institutes of Health | Wetherby, [NAME] | Florida State University | 529536
1/5-Randomized trial of parent training for young children with autism | National Institutes of Health | Scahill, [NAME] | Yale University | 447909
2/5-Randomized trial of parent training for young children with autism | National Institutes of Health | Lecavalier, [NAME] | The Ohio State University | 230104
3/5-Randomized trial of parent training for young children with autism | National Institutes of Health | Smith, Tristram | University of Rochester | 241762
4/5-Randomized trial of parent training for young children with autism | National Institutes of Health | Swiezy, [NAME] | Indiana University-Purdue University Indianapolis | 242552
5/5-Randomized trial of parent training for young children with autism | National Institutes of Health | [NAME], [NAME] | University of Pittsburgh | 238613
ACE Network: A multi-site randomized study of intensive treatment for toddlers with autism | National Institutes of Health | Rogers, [NAME] | University of California, [NAME] | 2920093
4SE. Convene a workshop to advance the understanding of clinical subtypes and treatment personalization (i.e., what are the core symptoms to target for treatment studies) by 2011. IACC Recommended Budget: $50,000. | red | 0 projects | 0
4SF. Launch five randomized controlled trials of interventions including biological signatures and other measures to predict response, and monitor quality of life and functional outcomes, in each of the following groups: <ul>  <li>Five trials in infants and toddlers by 2013. IACC Recommended Budget: $30,000,000 over 5 years.</li> <[NAME]Three randomized controlled trials of interventions for school-aged children and/or adolescents by 2013. IACC Recommended Budget: $18,000,000 over 5 years.</li> <[NAME]Three trials for adults by 2014. IACC Recommended Budget: $18,000,000 over 5 years.</li> </ul> | green | 30 projects | 7575212.03
Project Title | Funder | Principal Investigator | Institution | Funding
Evidence-based cognitive rehabilitation to improve functional outcomes for young adults with autism spectrum disorders | Autism Speaks | Minshew, [NAME] | University of Pittsburgh | 100000
Integrated play groups: Promoting social communication and symbolic play with peers across settings in children with autism | Autism Speaks | [NAME], [NAME] | San Francisco State University | 127497
2/3-Multisite RCT of early intervention for spoken communication in autism | National Institutes of Health | Smith, Tristram | University of Rochester | 395531
3/3 CBT for anxiety disorders in autism: Adapting treatment for adolescents | National Institutes of Health | [NAME], [NAME] | University of Miami | 41570
1/3 CBT for anxiety disorders in autism: Adapting treatment for adolescents | National Institutes of Health | Wood, [NAME] | University of California, Los Angeles | 285075
3/3-Atomoxetine placebo and parent training in autism | National Institutes of Health | Smith, Tristram | University of Rochester | 277198
1/3-Atomoxetine placebo and parent training in autism | National Institutes of Health | Handen, [NAME] | University of Pittsburgh | 272700
1/3-Multisite RCT of early intervention for spoken communication in autism | National Institutes of Health | Kasari, [NAME] | University of California, Los Angeles | 547162
3/3-Multisite RCT of early Intervention for spoken communication in autism | National Institutes of Health | Landa, Rebecca | Kennedy Krieger Institute | 815668
ACE Center: Risk and protective factors in the development of associated symptoms in autism | National Institutes of Health | Estes, Annette | University of Washington | 169876
2/3 CBT for anxiety disorders in autism: Adapting treatment for adolescents | National Institutes of Health | Storch, [NAME] | University of South Florida | 236579
2/3-Atomoxetine placebo and parent training in autism | National Institutes of Health | Aman, [NAME] | Ohio State University | 361873
The mirror neuron system in children with autism | Simons Foundation | Bernier, [NAME] | University of Washington | 59078.28
HCC: Collaborative research: Social-emotional technologies for autism spectrum disorders | National Science Foundation | [NAME], [NAME] | The Groden Center, Inc. | 46086.5
HCC: Collaborative research: Social-emotional technologies for autism spectrum disorders | National Science Foundation | Picard, Rosalind | Massachusetts Institute of Technology | 175362.25
ACE Network: Early pharmacotherapy guided by biomarkers in autism | National Institutes of Health | Chugani, [NAME] | Wayne State University | 1000000
Biomarkers in Autism of Aripiprazole and Risperidone Treatment (BAART) | National Institutes of Health | Devane, [NAME] | Medical University of South Carolina | 619865
Neurocognitive markers of response to treatment in autism | National Institutes of Health | Young, Gregory | University of California, [NAME] | 76500
The comparison of three behavioral therapy approaches for children with autism | National Institutes of Health | Quinn, [NAME] | University of Rhode Island | 50664
Predictors of effects of propranolol on language & connectivity in autism | Health Resources and Services Administration | [NAME], [NAME] | University of Missouri | 184288
A sibling mediated imitation intervention for young children with autism | Autism Speaks | Meyer, [NAME] | Michigan State University | 0
Early intervention for children screened positive for autism by the First Year Inventory | Autism Speaks | Baranek, [NAME]; Watson, [NAME]; [NAME], [NAME]; Crais, [NAME] | University of North Carolina at Chapel Hill | 0
Enhancing inter-subjectivity in infants at high risk for autism | Autism Speaks | [NAME], [NAME]; [NAME], [NAME]; [NAME], Isabel; Zwaigenbaum, Lonnie; [NAME], [NAME] | IWK Health Centre/Dalhousie University; University of Toronto; University of Alberta; The Hospital for Sick Children | 0
Evaluating behavioral and neural effects of social skills intervention for school-age children with autism spectrum disorders | Autism Speaks | Wang, [NAME]; Soorya, Latha | Mount Sinai School of Medicine | 0
Neural and behavioral outcomes of social skills groups in children with ASD | National Institutes of Health | Wang, [NAME]; Soorya, Latha | Mount Sinai School of Medicine | 290251
Social cognition and interaction training for adolescents with high functioning autism | Autism Speaks | [NAME], [NAME]; [NAME], [NAME] | University of North Carolina at Chapel Hill | 0
A randomized clinical trial of cognitive enhancement therapy for adults with autism spectrum disorders | Department of Defense | Minshew, [NAME] | University of Pittsburgh | 1412388
Improving synchronization and functional connectivity in autism spectrum disorders through plasticity-induced rehabilitation training | Department of Defense | Pineda, Jaime | University of California, San Diego | 0
Enhancing understanding and use of conversational rules in school-aged speakers with autism spectrum disorders | Autism Science Foundation | [NAME], Sarita | Yale University | 0
Prelinguistic symptoms of autism spectrum disorders in infancy | Autism Science Foundation | [NAME], [NAME] | University of California, Los Angeles | 30000
(New to 2010) 4SG. Support at least five studies on interventions for nonverbal individuals with ASD by 2012. Such studies may include:     o Projects examining service-provision models that enhance access to augmentative and alternative communication (AAC) supports in both classroom and adult service-provision settings, such as residential service-provision and the impact of such access on quality of life, communication, and behavior;     o Studies of novel treatment approaches that facilitate communication skills in individuals who are nonverbal, including the components of effective AAC approaches for specific subpopulations of people with ASD; and     o Studies assessing access and use of AAC for children and adults with ASD who have limited or partially limited speech and the impact on functional outcomes and quality of life. IACC Recommended Budget: $3,000,000 over 2 years. | green | 11 projects | 1907721
Project Title | Funder | Principal Investigator | Institution | Funding
A novel parent directed intervention to enhance language development in nonverbal children with ASD | Autism Speaks | [NAME], [NAME] | University of California, Los Angeles | 28000
A randomized controlled trial of two treatments for verbal communication | Autism Speaks | [NAME], [NAME]; [NAME], [NAME] | Yale Child Study Center | 150000
Developmental and augmented intervention for facilitating expressive language | Autism Speaks | Kasari, [NAME]; Kaiser, [NAME]; Landa, Rebecca; [NAME], [NAME] | University of California, Los Angeles; Vanderbilt University; Kennedy Krieger Institute; University of Michigan | 558000
Making words meet: Using computerized feedback to facilitate word combinations in children with ASD | Autism Speaks | [NAME], [NAME] | University of Illinois at Urbana-Champaign | 89518
Technology support for interactive and collaborative visual schedules | Autism Speaks | Hayes, Gillian | University of California, Irvine | 0
Visualizing voice | Autism Speaks | Hailpern, [NAME] | University of Illinois at Urbana Champaign | 28000
Do animations facilitate symbol understanding in children with autism? | Department of Education | Schlosser, Ralf | Northeastern University | 199996
Hy Weinberg Center for Communication Disorders | Department of Education | Sabbague, [NAME] | Adelphi University | 0
Communication success and AAC: A model of symbol acquisition | National Institutes of Health | [NAME], [NAME] | University of Kansas | 343664
Contingency analyses of observing and attending in intellectual disabilities | National Institutes of Health | [NAME], [NAME] | University of Massachusetts Medical School | 298293
Relational stimulus control management in neurodevelopmental disabilities | National Institutes of Health | Lionello-Denolf, [NAME] | University of Massachusetts Medical School | 212250
(New to 2010) 4SH. Support at least two studies that focus on research on health promotion and prevention of secondary conditions in people with ASD by 2012. Secondary conditions of interest include weight issues and obesity, injury, and co-occurring psychiatric and medical conditions. IACC Recommended Budget: $5,000,000 over 3 years. | yellow | 2 projects | 225877
Project Title | Funder | Principal Investigator | Institution | Funding
Treatment of sleep disturbances in young children with autism | National Institutes of Health | [NAME], [NAME] | University of Pittsburgh | 225877
Project Lifesaver Program | Autism Speaks | [NAME], Leo | Burlington County Sheriff's Department | 0
4LA. Complete at least three randomized controlled trials on medications targeting core symptoms in people with ASD of all ages by 2014. IACC Recommended Budget: $22,200,000 over 5 years. | yellow | 11 projects | 1924932
Project Title | Funder | Principal Investigator | Institution | Funding
The effects of oxytocin on complex social cognition in autism spectrum disorders | National Institutes of Health | Bartz, [NAME] | Mount Sinai School of Medicine | 285221
Trial of a glutamate antagonist in the treatment of OCD and autistic disorders | National Institutes of Health | Swedo, [NAME] | National Institutes of Health | 770674
ACE Center: The pharmacogenetics of treatment for insistence sameness in autism | National Institutes of Health | Owley, [NAME] | University of Illinois at Chicago | 382540
ACE Center: Understanding repetitive behavior in autism | National Institutes of Health | McCracken, [NAME] | University of California, Los Angeles | 326665
Developing treatment, treatment validation, and treatment scope in the setting of an autism clinical trial | Department of Defense | [NAME], [NAME] | University of Medicine & Dentistry of New Jersey - [NAME] Johnson Medical School | 0
Developing treatment, treatment validation, and treatment scope in the setting of an autism clinical trial | Department of Defense | Novotny, [NAME] | University of Medicine & Dentistry of New Jersey - [NAME] Johnson Medical School | 0
Developing treatment, treatment validation, and treatment scope in the setting of an autism clinical trial | Department of Defense | [NAME], [NAME] | University of Medicine & Dentistry of New Jersey | 0
Association of cholinergic system dysfunction with autistic behavior in fragile X syndrome: Pharmacologic and imaging probes | Autism Speaks | Reiss, [NAME] | Stanford University | 94832
Clinical Trials Network | Autism Speaks | Staff Member | Autism Speaks (AS) | 0
Neuronal nicotinic receptor modulation in the treatment of autism: A pilot trial of mecamylamine | Autism Speaks | [NAME], [NAME] | The Ohio State University | 0
Randomized phase 2 trial of RAD001 (an MTOR inhibitor) in patients with tuberous sclerosis complex | Autism Speaks | Sahin, [NAME] | Childrens Hospital Boston | 65000
4LB. Develop interventions for siblings of people with ASD with the goal of reducing risk recurrence by at least 30% by 2014. IACC Recommended Budget: $6,700,000 over 5 years. | yellow | 3 projects | 307348.59
Project Title | Funder | Principal Investigator | Institution | Funding
Initial investigation of prevention of ASD in infants at risk | National Institutes of Health | Rogers, [NAME]; [NAME], [NAME] | University of California, [NAME] | 263591
Preventing autism via very early detection and intervention | Center for Autism and Related Disorders | Tarbox, [NAME] | Center for Autism and Related Disorders (CARD) | 14256
Executive functioning, theory of mind, and neurodevelopmental outcomes | Simons Foundation | Warren, [NAME] | Vanderbilt University Medical Center | 29501.59
4LC. Conduct at least one study to evaluate the safety and effectiveness of medications commonly used in the treatment of co-occurring conditions or specific behavioral issues in people with ASD by 2015. IACC Recommended Budget: $10,000,000 over 5 years. | green | 7 projects | 2302240
Project Title | Funder | Principal Investigator | Institution | Funding
Targeted pharmacologic interventions for autism | National Institutes of Health | McDougle, [NAME] | Indiana University-Purdue University Indianapolis | 370481
3/4-RUPP autism network: Guanfacine for the treatment of hyperactivity in PDD | National Institutes of Health | McCracken, [NAME] | University of California, Los Angeles | 391103
4/4-RUPP Autism Network: Guanfacine for the treatment of hyperactivity in PDD | National Institutes of Health | Scahill, [NAME] | Yale University | 564924
Pharmacotherapy of pervasive developmental disorders | National Institutes of Health | Stigler, Kimberly | Indiana University-Purdue University Indianapolis | 184587
1/4-RUPP autism network: Guanfacine for the treatment of hyperactivity in PDD | National Institutes of Health | McDougle, [NAME] | Indiana University-Purdue University Indianapolis | 366035
2/4-RUPP autism network: Guanfacine for the treatment of hyperactivity in PDD | National Institutes of Health | King, [NAME] | Seattle Children's Hospital | 325136
Mirtazapine treatment of anxiety in children and adolescents with pervasive developmental disorders | Autism Speaks | McDougle, [NAME] | Indiana University | 99974
(New to 2010) 4LD. Support at least five community-based studies that assess the effectiveness of interventions and services in broader community settings by 2015. Such studies may include comparative effectiveness research studies that assess the relative effectiveness of:     o Different and/or combined medical, pharmacological, nutritional, behavioral, service-provision, and parent- or caregiver-implemented treatments;     o Scalable early intervention programs for implementation in underserved, low-resource, and low-literacy populations; and     o Studies of widely used community intervention models for which extensive published data are not available. Outcome measures should include assessment of potential harm as a result of autism treatments, as well as positive outcomes. IACC Recommended Budget: $37,500,000 over 5 years. | green | 32 projects | 8756832
Project Title | Funder | Principal Investigator | Institution | Funding
Peer-mediated interventions for elementary school students with autism spectrum disorders | Organization for Autism Research | Blakeley-Smith, [NAME] | University of Colorado Denver | 10000
Effects of parent-implemented intervention for toddlers with autism spectrum disorders | Autism Speaks | Wetherby, [NAME]; Lord, [NAME] | Florida State University; University of Michigan | 0
Promoting communication skills in toddlers at risk for autism | Autism Speaks | Kasari, [NAME]; Sigman, Marian | University of California, Los Angeles | 254571
Comparison of two comprehensive treatment models for preschool-aged children with autism spectrum disorders and their families | Department of Education | Odom, [NAME] | University of North Carolina at Chapel Hill | 967343
Implementing evidence-based social skills interventions in public school settings | Autism Science Foundation | Locke, [NAME] | University of Pennsylvania/Children's Hospital of Philadelphia | 40000
Early intervention in an underserved population | Autism Speaks | Lord, [NAME] | University of Michigan | 73763
Peer-mediated social skills training | Autism Speaks | Levey, [NAME] | Seacoast Mental Health Center | 0
Promoting early social-communicative competency in toddlers with autism | Autism Speaks | Schertz, [NAME]; [NAME], [NAME]; [NAME], [NAME] | Indiana University; University of North Carolina at Chapel Hill; University of Kansas | 0
Pivotal response group treatment for parents of young children with autism | Autism Speaks | [NAME], [NAME] | Stanford University | 99996
Sibling-mediated social communicative intervention for children with autism spectrum disorder | National Institutes of Health | [NAME], [NAME] | University of Idaho | 70983
Software to enrich the noun lexicons and lexical learning of children with autism | National Institutes of Health | Wilson, [NAME] | Laureate Learning Systems, Inc. | 191819
The impact of classroom climate on autism intervention fidelity and outcomes | National Institutes of Health | Dingfelder, Hilary | University of Pennsylvania | 41380
High school inclusion program for students with autism spectrum disorders | Organization for Autism Research | Hughes, [NAME] | Vanderbilt University | 1991
The effectiveness of an evidence-based parent training intervention in a community service setting | Autism Speaks | Stadnick, [NAME] | University of California, San Diego | 28000
Translation of evidence-based treatment to classrooms | Autism Speaks | Schreibman, [NAME] | University of California, San Diego | 12500
Developing a 3D-based virtual learning environment for use in schools to enhance the social competence of youth with autism spectrum disorder | Department of Education | Laffey, [NAME] | University of Missouri | 492790
Developing a school-based social competence intervention (SCI) | Department of Education | Sticher, [NAME] | University of Missouri | 373131
Development of an intervention to enhance the social competencies of children with Asperger's/high functioning autism spectrum disorders | Department of Education | Volker, Martin | University at Buffalo, The State University of New York | 266940
Efficacy of a parent-mediated intervention for one-year-olds at risk for autism | Department of Education | [NAME], [NAME] | University of North Carolina at Chapel Hill | 623086
Handheld technology to assist students with autism spectrum disorder | Department of Education | Tedesco, [NAME] | [NAME], LLC | 99735
Parent-implemented social-pragmatic communication intervention for young children with developmental disabilities | Department of Education | Angell, [NAME] | Illinois State University | 282246
Improving social-communication, literacy, and adaptive behaviors for young children with autism spectrum disorders | Department of Education | [NAME], [NAME] | University of Kansas | 745000
[NAME] : The audio/video guidance repository for life skills | Department of Education | Ayres, [NAME] | University of Georgia | 408294
Peer support and peer network interventions to improve peer relationships and school engagement | Department of Education | [NAME], [NAME] | Board of Regents of the University of Wisconsin System | 630967
Translating pivotal response training into classroom environments | Department of Education | Stahmer, Aubyn | [NAME] Hospital Health Center | 495451
Related services intervention for expressive and receptive language skills in autism spectrum disorder and in cognitive impairment | Department of Education | Camarata, [NAME] | Vanderbilt University | 301995
Social communication and symbolic play intervention for preschoolers with autism | Department of Education | [NAME], [NAME] | University of North Carolina at Chapel Hill | 322799
Parent-mediated vs. center-based intervention for toddlers with ASD: An RCT | Health Resources and Services Administration | Landa, Rebecca | Kennedy Krieger Institute | 400000
A randomized control study of relationship focused intervention with young children with ASD | National Institutes of Health | Mahoney, [NAME] | Case Western Reserve University | 272003
ACE Center: Optimizing social and communication outcomes for toddlers with autism | National Institutes of Health | Kasari, [NAME] | University of California, Los Angeles | 292074
Parenting your young child with autism: A web-based tutorial | National Institutes of Health | Kobak, [NAME] | Center for Psychological Consultation | 249399
Randomized controlled trial of the P.L.A.Y. Project intervention for autism | National Institutes of Health | [NAME], [NAME] | [NAME], [NAME], PLC | 708576
4O. Not specific to Question 4 objectives | not applicable | 49 projects | 6290633.67
Project Title | Funder | Principal Investigator | Institution | Funding
Daily living and community skills video game for children with developmental disabilities | Department of Education | Maguire, [NAME] | Sandbox Learning Company | 99258
Survey on treatment for children with autism with and without seizures | Autism Research Institute | Frye, [NAME] | Children's Learning Institute | 7500
Teaching children with ASD to understand metaphor | Center for Autism and Related Disorders | Tarbox, [NAME] | Center for Autism and Related Disorders (CARD) | 25052
Teaching children with ASD to understand sarcasm | Center for Autism and Related Disorders | Tarbox, [NAME] | Center for Autism and Related Disorders (CARD) | 25052
Identifying factors that predict response to intervention | Center for Autism and Related Disorders | Tarbox, [NAME] | Center for Autism and Related Disorders (CARD) | 21965
Long-term follow-up of children with autism who recovered | Center for Autism and Related Disorders | Granpeesheh, Doreen | Center for Autism and Related Disorders (CARD) | 33965
Teaching theory of mind skills to children with ASD | Center for Autism and Related Disorders | Tarbox, [NAME] | Center for Autism and Related Disorders (CARD) | 24025
An interactive social tutoring system to improve and measure social goals for students with high functioning autism spectrum disorders | Department of Education | [NAME], [NAME] | 3-C Institute for Social Development | 74995
Animated Visual Supports for Social Skills (AViSSS) | Department of Education | Smith, Sean | University of Kansas Medical Center Research Institute, Inc. | 28571
Altering motivational variables to treat stereotyped behavior | Autism Speaks | Rapp, [NAME] | St. Cloud State University | 0
Enhancing social communication for children with HFA | Autism Speaks | Weiss, Patrice | University of Haifa | 37829
Evaluating a 3D VLE for developing social competence | Autism Speaks | Laffey, [NAME] | University of Missouri | 84997
Age and treatment intensity in behavioral intervention | Center for Autism and Related Disorders | Granpeesheh, Doreen | Center for Autism and Related Disorders (CARD) | 34879
Assessing preference for reinforcers in children with autism | Center for Autism and Related Disorders | [NAME], [NAME] | Center for Autism and Related Disorders (CARD) | 29684
Behavioral intervention for working memory in children with autism | Center for Autism and Related Disorders | Tarbox, [NAME] | Center for Autism and Related Disorders (CARD) | 30000
Establishing conditioned reinforcers for children with ASD | Center for Autism and Related Disorders | [NAME], [NAME] | Center for Autism and Related Disorders (CARD) | 43056
Evaluating differential patterns of dishabituation in children with ASD | Center for Autism and Related Disorders | Bishop, [NAME] | Center for Autism and Related Disorders (CARD) | 17025
The Autism Curriculum Encyclopedia® (ACE®) | Department of Education | Mansfield, [NAME] | New England Center for Children, Inc. | 47500
Using robotics to promote social cognitive skills in the inclusive classroom | Department of Education | Lathan, Corinna | Anthrotronix, Inc. | 74908
Utility of social robots for promoting joint attention in infants and toddlers with disabilities | Department of Education | Dunst, [NAME] | Orelena Hawks Puckett Institute | 199650
Teaching children to comprehend rules containing "if/then" | Center for Autism and Related Disorders | Tarbox, [NAME] | Center for Autism and Related Disorders (CARD) | 38994
Teaching children to identify causes of others' emotions | Center for Autism and Related Disorders | Tarbox, [NAME] | Center for Autism and Related Disorders (CARD) | 20687
Teaching children with ASD to tell socially appropriate "white lies" | Center for Autism and Related Disorders | Bergstrom, [NAME] | Center for Autism and Related Disorders (CARD) | 18078
[NAME] Autism Preschool | Department of Education | [NAME], Kathy | Hattie Larlham Research Institute | 0
The American History for ALL Project | Department of Education | Amador, Carmen | New York City Department of Education, District 75 | 117326
MRI: Acquisition of instruments for interaction, learning, and perception in virtual environments | National Science Foundation | Bodenheimer, [NAME] | Vanderbilt University | 59883.67
SBIR Phase I: Electronic reading tool: Story interactive media player | National Science Foundation | Camacho, [NAME] | Echelon Group, Inc. | 150000
Comparative effectiveness of therapies for children with autism spectrum disorders | Agency for Healthcare Research and Quality | McPheeters, [NAME] | Agency for Healthcare Research and Quality and Vanderbilt University | 0
Contingency manipulation in discrete trial interventions for children with autism | National Institutes of Health | Jones, Brent | University of Massachusetts Medical School | 212250
Delayed motor learning in autism | National Institutes of Health | Dizio, [NAME] | Brandeis University | 338740
Design & synthesis of novel CNS-active oxytocin and vasopressin receptor ligands | National Institutes of Health | [NAME], [NAME] | The Scripps Research Institute | 560535
ACE Center: Clinical Phenotype: Treatment Response Core | National Institutes of Health | Schreibman, [NAME] | University of California, San Diego | 210667
Adapting cognitive enhancement therapy for ASD | National Institutes of Health | Minshew, [NAME] | University of Pittsburgh | 205785
Autism and the development of relational awareness | National Institutes of Health | Diamond, [NAME] | University of British Columbia | 598579
Building a selective inhibitory control tone in autism: An rTMS study | National Institutes of Health | Casanova, [NAME] | University of Louisville | 222000
Stimulus overselectivity in visual discrimination: Analysis and remediation (supplement) | National Institutes of Health | [NAME], [NAME] | University of Massachusetts Medical School | 265928
Development of an executive function-based intervention for autism spectrum disorder | National Institutes of Health | [NAME], [NAME]; [NAME], [NAME] | Children's Research Institute | 258000
Virtual reality and augmented social training for autism | National Institutes of Health | [NAME], [NAME] | University of California, [NAME] | 176185
Desensitization techniques for difficult behaviors | Southwest Autism Research & Resource Center | Openden, [NAME] | Southwestern Autism Research & Resource Center (SARRC) | 0
A novel adaptive transactional virtual reality-based assistive technology for autism intervention | National Science Foundation | Sarkar, Nilanjan | Vanderbilt University | 100000
Robot child interactions as an intervention tool for children with autism | National Institutes of Health | Bhat, [NAME] | University of Connecticut | 200236
A cognitive-behavioral intervention for children with autism spectrum disorders | National Institutes of Health | White, [NAME] | Virginia Polytechnic Institute and State University | 132142
Genetic components influencing the feline - human social bond | National Institutes of Health | Lyons, Leslie | University of California, [NAME] | 76500
Guiding visual attention to enhance discrimination learning | National Institutes of Health | Carlin, [NAME] | University of Massachusetts Medical School | 146861
Novel, subtype selective potentiators of nicotinic acetycholine receptors | National Institutes of Health | [NAME], [NAME] | University of Alaska Fairbanks | 325757
Virtual environment for social information processing (VESIP) | Department of Education | [NAME], [NAME] | Soar Technology, Inc. | 74964
HCC-Medium: Personalized socially-assistive human-robot interaction: Applications to autism spectrum disorder | National Science Foundation | Mataric, Maja | University of Southern California | 246386
Sensorimotor learning of facial expressions: A novel intervention for autism | National Institutes of Health | [NAME], Marian | University of California, San Diego | 494454
Does training in acting foster theory of mind, empathy, and emotion regulation? | National Science Foundation | Winner, [NAME] | Boston College | 99785
This data file was dynamically generated.