Spreadsheet: ae67f87f-c276-4002-b56c-43df5858724d
Sheet: Sheet1

Test Referenced | Entry Type | Mayo ID | Description | Reporting Description | Method | Collection Container | Temperature | Stability | [NAME] | Unit of Measure | [NAME] | Minimum Volume | Reject Due To | Reference Values | Days/Times Performed | Analytic Time | Maximum Lab Time | CPT Units | CPT Code | LOINC® Code | LOINC® Attributes | Always Performed | Orderable Separately | Performing Location
25HDN | Test | 25HDN | 25-[NAME] and [NAME], Serum | 25-[NAME] and [NAME], S | Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) | Plain, Red-Top Tube: Red |  |  | 0.5 | mL | Container/Tube:  Preferred: Red top  Acceptable: Serum gel [NAME]: 0.5 mL Forms: If not ordering electronically, submit a General Request Form (Supply T239) with the specimen. | 0.25 mL | Hemolysis	Mild OK; Gross OK Thawing	Warm OK; Cold OK Lipemia	Mild OK; [NAME] OK Icterus	Mild OK; [NAME] OK Other	NA | TOTAL 25-HYDROXYVITAMIN D2 AND [NAME] (25-OH-VitD) <10 ng/mL (severe deficiency)* 10-19 ng/mL (mild to moderate deficiency)** 20-50 ng/mL (optimum levels)*** 51-80 ng/mL (increased risk of hypercalciuria)**** >80 ng/mL (toxicity possible)***** *Could be associated with osteomalacia or rickets **May be associated with increased risk of osteoporosis or secondary hyperparathyroidism ***Optimum levels in the healthy population; patients with bone disease may benefit from higher levels within this range ****Sustained levels >50 ng/mL 25OH-VitD along with prolonged calcium supplementation may lead to hypercalciuria and decreased renal function ****80 ng/mL is the lowest reported level associated with toxicity in patients without primary hyperparathyroidism who have normal renal function. Most patients with toxicity have levels >150 ng/mL. Patients with renal failure can have very high 25-OH-VitD levels without any signs of toxicity, as renal conversion to the active hormone 1,25-OH-VitD is impaired or absent.   These reference ranges represent clinical decision values, based on the 2011 Institute of Medicine report, that apply to males and females of all ages, rather than population-based reference values. Population reference ranges for 25-OH-VitD vary widely depending on ethnic background, age, geographic location of the studied populations, and the sampling season. Population-based ranges correlate poorly with serum 25-OH-VitD concentrations that are associated with biologically and clinically relevant vitamin D effects and are therefore of limited clinical value. | Monday through Friday; [NAME] until 2:30 p.m.; Saturday: [NAME] until 12 p.m. Specimens on patients who are <1 year old are only performed on Monday and Thursday. | 2 days | 5 days | 1 | 82306 |  |  |  |  | Rochester
25HDN | [NAME] | SERUM | Serum |  |  |  | Refrigerated | 14 days
25HDN | Result | 2897 | 25-Hydroxy D2 | 25-Hydroxy D2 | Numeric |  |  |  |  | ng/mL |  |  |  |  |  |  |  |  |  | 49054-0 | 25-Hydroxycalciferol:MCnc:Pt:Ser/Plas:Qn:
25HDN | Result | 2898 | 25-Hydroxy D3 | 25-Hydroxy D3 | Numeric |  |  |  |  | ng/mL |  |  |  |  |  |  |  |  |  | 1989-3 | Calcitriol:MCnc:Pt:Ser/Plas:Qn:
25HDN | Result | 83670 | 25-Hydroxy D Total | 25-Hydroxy D Total | Numeric |  |  |  |  | ng/mL |  |  |  |  |  |  |  |  |  | 62292-8 | Calcidiol:MCnc:Pt:Ser/Plas:Qn: