Spreadsheet: 6255863a-c061-441c-af99-f90418a663ed
Sheet: Table S1

Table S1.  Top gene sets enriched in NAC-treated Nkx3.1-/- anterior prostate
* Gene sets with a [NAME] q-value < 0.25 are listed*
[NAME] | [NAME] | Enrichment Score | Normalized Enrichment Score | NOM p-val | [NAME] q-val
LEE_LIVER_CANCER_MYC_E2F1_DN | 54 | 0.6687453 | 2.0785728 | 0 | 0.029625272
LIAN_LIPA_TARGETS_3M | 63 | 0.6321115 | 2.069667 | 0 | 0.016502868
LEE_LIVER_CANCER_E2F1_DN | 54 | 0.6587046 | 2.0366783 | 0 | 0.01495713
LEE_LIVER_CANCER_MYC_DN | 51 | 0.6448645 | 2.0146315 | 0 | 0.015886858
LIAN_LIPA_TARGETS_6M | 78 | 0.6113733 | 2.005228 | 0 | 0.015247013
HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN | 80 | 0.5729221 | 1.9349073 | 0 | 0.045937225
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN | 63 | 0.60677373 | 1.9301265 | 0 | 0.042399097
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | 147 | 0.5361392 | 1.9250312 | 0 | 0.04079714
GAL_LEUKEMIC_STEM_CELL_DN | 185 | 0.5160865 | 1.923289 | 0 | 0.037865184
CADWELL_ATG16L1_TARGETS_UP | 95 | 0.5614175 | 1.9072229 | 0 | 0.043294154
KEGG_PPAR_SIGNALING_PATHWAY | 57 | 0.60990304 | 1.9062803 | 0 | 0.039821543
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | 250 | 0.4959732 | 1.9009372 | 0 | 0.039262693
PAL_PRMT5_TARGETS_DN | 28 | 0.6665161 | 1.8968568 | 0 | 0.03865745
REACTOME_STRIATED_MUSCLE_CONTRACTION | 28 | 0.6805471 | 1.8847986 | 0 | 0.043413986
LEE_LIVER_CANCER_DENA_DN | 62 | 0.59348744 | 1.884318 | 0 | 0.040859234
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN | 25 | 0.70108426 | 1.8740361 | 0 | 0.045713473
LEE_LIVER_CANCER_MYC_TGFA_DN | 55 | 0.5975709 | 1.8576286 | 0 | 0.05319546
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY | 65 | 0.5749559 | 1.8510147 | 0 | 0.054790545
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_DN | 50 | 0.59249157 | 1.8477948 | 0 | 0.05458729
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_DN | 69 | 0.56383026 | 1.8429879 | 0 | 0.056007944
GERY_CEBP_TARGETS | 112 | 0.531063 | 1.842648 | 0 | 0.053504363
KEGG_HEMATOPOIETIC_CELL_LINEAGE | 65 | 0.5723646 | 1.8285016 | 0 | 0.06185073
POOLA_INVASIVE_BREAST_CANCER_UP | 225 | 0.47933823 | 1.8272911 | 0 | 0.060084313
VERRECCHIA_EARLY_RESPONSE_TO_TGFB1 | 48 | 0.5884393 | 1.8125929 | 0.0015625 | 0.069638744
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | 75 | 0.5459355 | 1.7942773 | 0 | 0.08516771
SHEPARD_BMYB_MORPHOLINO_DN | 146 | 0.49559382 | 1.7938854 | 0 | 0.082118616
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP | 139 | 0.5059562 | 1.793403 | 0 | 0.07948422
CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | 72 | 0.5432615 | 1.7903324 | 0.0029542097 | 0.0793048
FURUKAWA_DUSP6_TARGETS_PCI35_DN | 57 | 0.5594778 | 1.776866 | 0 | 0.09093076
NADERI_BREAST_CANCER_PROGNOSIS_UP | 32 | 0.6238936 | 1.7764797 | 0.0032102729 | 0.08840661
RICKMAN_HEAD_AND_NECK_CANCER_F | 50 | 0.56764376 | 1.7703884 | 0.003030303 | 0.09202219
KEGG_COMPLEMENT_AND_COAGULATION_CASCADES | 58 | 0.5550212 | 1.7651378 | 0.0014858841 | 0.09525036
REACTOME_PLATELET_DEGRANULATION | 80 | 0.53123724 | 1.7592402 | 0 | 0.09917589
URS_ADIPOCYTE_DIFFERENTIATION_DN | 28 | 0.6436915 | 1.7524512 | 0.0077639753 | 0.10388051
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | 151 | 0.48378676 | 1.7516683 | 0 | 0.10200334
MCLACHLAN_DENTAL_CARIES_UP | 161 | 0.4817832 | 1.750189 | 0 | 0.101049244
REACTOME_GPCR_LIGAND_BINDING | 346 | 0.44626322 | 1.7499892 | 0 | 0.09856767
LEE_LIVER_CANCER_TOP50 | 32 | 0.6084294 | 1.7460608 | 0.0015432099 | 0.10067183
SETLUR_PROSTATE_CANCER_TMPRSS2_ERG_FUSION_DN | 17 | 0.702183 | 1.7350302 | 0.01369863 | 0.11078573
LE_EGR2_TARGETS_UP | 97 | 0.5113811 | 1.7336284 | 0 | 0.10968774
MCLACHLAN_DENTAL_CARIES_DN | 184 | 0.46313342 | 1.7209318 | 0 | 0.123567514
LEE_LIVER_CANCER | 32 | 0.6084294 | 1.720176 | 0.004862237 | 0.12173186
BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN | 39 | 0.58452857 | 1.706518 | 0.0076687117 | 0.13871303
SABATES_COLORECTAL_ADENOMA_DN | 227 | 0.45166668 | 1.7058127 | 0 | 0.13683037
STEARMAN_TUMOR_FIELD_EFFECT_UP | 40 | 0.58182126 | 1.702842 | 0.0047318614 | 0.13819508
YU_MYC_TARGETS_UP | 37 | 0.5795324 | 1.6981752 | 0.008237232 | 0.14195757
RICKMAN_HEAD_AND_NECK_CANCER_D | 20 | 0.6705969 | 1.6957783 | 0.0016474464 | 0.1422672
[NAME] | 215 | 0.44934806 | 1.6925439 | 0 | 0.14363305
WIELAND_UP_BY_HBV_INFECTION | 70 | 0.51887995 | 1.6798372 | 0.001447178 | 0.16001174
CAIRO_HEPATOBLASTOMA_POOR_SURVIVAL | 15 | 0.69675213 | 1.6751864 | 0.019017432 | 0.16461366
KEGG_LINOLEIC_ACID_METABOLISM | 17 | 0.66168547 | 1.6745199 | 0.019298246 | 0.16233131
MISHRA_CARCINOMA_ASSOCIATED_FIBROBLAST_UP | 18 | 0.6575708 | 1.6639119 | 0.01633987 | 0.17785785
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP | 148 | 0.4584104 | 1.6539901 | 0.0026455026 | 0.19257212
YAO_HOXA10_TARGETS_VIA_PROGESTERONE_UP | 74 | 0.50565267 | 1.6508822 | 0.005738881 | 0.19513217
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA1_UP | 55 | 0.5309392 | 1.648653 | 0.0030487804 | 0.19618909
SMID_BREAST_CANCER_RELAPSE_IN_LUNG_DN | 31 | 0.58500373 | 1.6456423 | 0.006504065 | 0.19850737
LIU_VAV3_PROSTATE_CARCINOGENESIS_UP | 76 | 0.50116956 | 1.6443701 | 0.0029895366 | 0.19724143
VALK_AML_WITH_CEBPA | 29 | 0.6001114 | 1.6437849 | 0.009244992 | 0.19484773
VERRECCHIA_RESPONSE_TO_TGFB1_C1 | 18 | 0.64663994 | 1.643337 | 0.017828202 | 0.19220601
[NAME] | 20 | 0.63395727 | 1.6364162 | 0.020066889 | 0.20107156
SHEPARD_BMYB_TARGETS | 55 | 0.50914204 | 1.6326399 | 0.007936508 | 0.20414296
SMID_BREAST_CANCER_LUMINAL_A_UP | 74 | 0.49246207 | 1.6280214 | 0.002919708 | 0.20953453
VARELA_ZMPSTE24_TARGETS_DN | 43 | 0.53797704 | 1.6241286 | 0.011456628 | 0.21382536
LE_EGR2_TARGETS_DN | 107 | 0.46778962 | 1.6239836 | 0.0014005603 | 0.2107894
GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN | 69 | 0.50413203 | 1.6193262 | 0.0030534351 | 0.21607605
KEGG_ECM_RECEPTOR_INTERACTION | 79 | 0.49583673 | 1.6107888 | 0.0028571428 | 0.22961438
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_DN | 15 | 0.65495086 | 1.6105131 | 0.025597269 | 0.22662857
NAKAJIMA_EOSINOPHIL | 18 | 0.64061457 | 1.6101897 | 0.02724359 | 0.22390446
REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | 45 | 0.5224501 | 1.6097274 | 0.012232416 | 0.22159219
REACTOME_MUSCLE_CONTRACTION | 48 | 0.52349156 | 1.6088699 | 0.016442452 | 0.22007108
[NAME] | 51 | 0.5165352 | 1.6074113 | 0.013761468 | 0.21986398
ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER | 119 | 0.4605241 | 1.6060758 | 0.0013717421 | 0.21962972
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_ERYTHROCYTE_UP | 134 | 0.45084536 | 1.6016752 | 0.0053333333 | 0.2250973
KOBAYASHI_EGFR_SIGNALING_24HR_DN | 215 | 0.4235164 | 1.6010021 | 0 | 0.22337162
SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP | 118 | 0.45125914 | 1.6008412 | 0.0028571428 | 0.22076608
CROMER_TUMORIGENESIS_DN | 38 | 0.5522817 | 1.5996325 | 0.010606061 | 0.22011091
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION | 248 | 0.41993952 | 1.5982062 | 0 | 0.21987835
[NAME] | 76 | 0.48386303 | 1.5967897 | 0.004470939 | 0.22007762
COLIN_PILOCYTIC_ASTROCYTOMA_VS_GLIOBLASTOMA_DN | 28 | 0.57561445 | 1.596765 | 0.020100502 | 0.21731324
CLASPER_LYMPHATIC_VESSELS_DURING_METASTASIS_DN | 32 | 0.5734557 | 1.594454 | 0.022364218 | 0.21933536
REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS | 16 | 0.65036243 | 1.5935286 | 0.016207455 | 0.21842566
KEGG_CELL_ADHESION_MOLECULES_CAMS | 102 | 0.4577551 | 1.586418 | 0.005738881 | 0.23009616
EBAUER_MYOGENIC_TARGETS_OF_PAX3_FOXO1_FUSION | 45 | 0.5218144 | 1.5834109 | 0.016819572 | 0.23311692
VERRECCHIA_RESPONSE_TO_TGFB1_C2 | 18 | 0.62823445 | 1.5830859 | 0.023217248 | 0.23101743
SABATES_COLORECTAL_ADENOMA_UP | 105 | 0.45681334 | 1.5817798 | 0.004092769 | 0.23069023
MOROSETTI_FACIOSCAPULOHUMERAL_MUSCULAR_DISTROPHY_UP | 17 | 0.6468799 | 1.5817508 | 0.036206897 | 0.22802712
LEE_LIVER_CANCER_CIPROFIBRATE_DN | 55 | 0.5064623 | 1.5811743 | 0.0106870225 | 0.22648443
MARKEY_RB1_CHRONIC_LOF_DN | 115 | 0.45384306 | 1.5805833 | 0.0069252076 | 0.22506492
SHEN_SMARCA2_TARGETS_DN | 247 | 0.4184847 | 1.580156 | 0 | 0.2233823
COULOUARN_TEMPORAL_TGFB1_SIGNATURE_DN | 97 | 0.45992443 | 1.5796864 | 0.0027777778 | 0.22157705
AMIT_SERUM_RESPONSE_240_MCF10A | 53 | 0.5030989 | 1.5744793 | 0.016320474 | 0.22937441
REACTOME_HEMOSTASIS | 245 | 0.40950993 | 1.5713743 | 0.0012886598 | 0.23322585
KONDO_PROSTATE_CANCER_WITH_H3K27ME3 | 139 | 0.4389249 | 1.5674336 | 0.0026666666 | 0.23858626
TANG_SENESCENCE_TP53_TARGETS_DN | 33 | 0.55285627 | 1.5668643 | 0.017460318 | 0.23726277
DELYS_THYROID_CANCER_UP | 364 | 0.3930679 | 1.5636852 | 0 | 0.24107304
RUIZ_TNC_TARGETS_DN | 112 | 0.4460216 | 1.5626462 | 0.0085227275 | 0.24070282
WANG_CISPLATIN_RESPONSE_AND_XPC_UP | 118 | 0.43991157 | 1.5614103 | 0.0027510317 | 0.24106328
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6 | 70 | 0.47864637 | 1.5604398 | 0.0075301207 | 0.24058749
[NAME] | 19 | 0.6155032 | 1.5566261 | 0.02866779 | 0.24581821