Spreadsheet: c121f51b-09b0-4683-ac02-3b9a947771ab
Sheet: Sheet1

Table S4: 309 pathways that are significantly associated to miRs in breast cancer. Each pathway is annotated with its leading edge genes and important miRs. P-Values are indicated in parentheses. Furthermore, we indicate if a pathway is differentially expressed (DE) with [NAME] < 0.01. | Unnamed: 1 | Unnamed: 2 | Unnamed: 3
pathway | leading edges | DE | important miRs
REACTOME_PHASE_1_FUNCTIONALIZATION | PTGS2 CYP1A1 CYP1A2 MAOA MAOB FMO3 CYP2A6 CYP4A11 CYP3A4 PTGIS |  | hsa-miR-149 (7.4e-10) hsa-miR-101 (6.4e-08) hsa-miR-144 (0.0055)
REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | JUN FOS |  | hsa-miR-92 (1.3e-09) hsa-miR-144 (0.0017) hsa-miR-101 (0.0019) hsa-miR-181b (0.0039)
REACTOME_TRKA_SIGNALLING_FROM_THE_PLASMA_MEMBRANE | HRAS BRAF MAPK1 THEM4 NRAS GSK3A GSK3B [NAME] FRS2 MAPKAPK3 MAPKAPK2 BAD CAMK4 KRAS RIT1 [NAME] GRB2 SHC1 PRKCD MDM2 TRIB3 PIK3R2 MAP2K2 RPS6KB2 PRKAR2A AKT1S1 PRKAR1B TSC2 ADCY1 ADCY7 ADRBK1 ITPR3 STAT3 MAPK12 ADCY9 MAPK13 SRC AKT1 |  | [NAME] (6.5e-09) hsa-miR-320 (2.1e-05) hsa-let-7f (0.00015) hsa-miR-152 (0.00041)
REACTOME_GLUCOSE_REGULATION_OF_INSULIN_SECRETION | CACNB3 FH NDUFB11 NDUFB10 SDHC NDUFAB1 CYC1 UQCRQ UQCRH GCK MDH2 ALDOA [NAME] [NAME] ATP5H [NAME] UQCRC1 PFKL GAPDH NDUFA13 NDUFA11 [NAME] NDUFV3 NDUFV1 NDUFV2 CACNA1D NDUFS6 NDUFS8 NDUFS3 NDUFS2 ATP5G1 PFKFB4 PFKFB2 TPI1 COX6B1 COX6A1 SLC25A5 PGK1 NDUFC2 NDUFC1 NDUFB4 NDUFB9 NDUFB1 NDUFB2 ENO2 NDUFA2 NDUFA3 NDUFA8 NDUFA6 NDUFA7 NDUFA1 GPI |  | hsa-miR-148b (0.0071)
REACTOME_MRNA_3_END_PROCESSING | NCBP2 [NAME] PAPOLA CSTF3 [NAME] |  | hsa-miR-125a (0.00011) hsa-miR-125b (0.00093) hsa-miR-1 (0.0036)
REACTOME_SIGNAL_AMPLIFICATION | [NAME] GNG13 GNG11 P2RY12 PLA2G4A |  | hsa-miR-485-3p (2.2e-29) hsa-miR-19b (2e-09) hsa-miR-218 (0.00017) hsa-miR-19a (0.0023) hsa-miR-543 (0.0025)
REACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH | HRAS MAPK1 CACNB3 NRAS PTK2 COL5A2 COL5A1 KRAS ARTN YWHAB GRB2 SPTBN2 MAP2K2 COL1A2 COL1A1 CACNA1D AGRN |  | [NAME] (0.0035) hsa-miR-30b (0.0068) hsa-miR-155 (0.0091)
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES | RAE1 SLC20A1 ABCA7 SLC13A2 SLC1A4 SLC1A1 SLC43A2 SLC7A11 GCK SLC11A1 SEH1L SLC24A2 SLC24A6 SLC39A10 SLC16A3 NUP188 TPR SLC39A7 SLC39A3 SLC39A1 NUP155 SLC9A8 SLC9A7 SLC9A1 NUP205 HK1 NUP214 NUP210 HK3 SLC4A8 SLC44A4 SLC2A1 NUP85 NUP98 NUP93 SLC12A7 SLC2A10 NUP50 NUP62 ABCD1 SLC4A2 SLC4A1 NUPL1 SLC38A5 SLC30A1 [NAME] |  | hsa-miR-217 (0.0016) hsa-miR-148a (0.0024)
REACTOME_CENTROSOME_MATURATION | TSGA14 [NAME] [NAME] TUBG1 TUBG2 NDE1 TUBA4A NEK2 ALMS1 CEP250 CETN2 YWHAG CEP72 CEP78 CEP70 FGFR1OP TUBGCP2 TUBB2C PCNT [NAME] PLK4 PLK1 ODF2 CEP164 CKAP5 | * | hsa-miR-185 (1.2e-18) hsa-miR-155 (7.6e-12) hsa-miR-125a (1.3e-09) hsa-miR-186 (1.3e-05) hsa-let-7g (9.5e-05) hsa-miR-217 (0.00032) hsa-miR-28 (0.00098) hsa-miR-132 (0.001) hsa-miR-212 (0.0013) hsa-miR-30c (0.0031)
REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | DBF4 RPA3 ORC1L CDC7 CDC6 POLA1 POLA2 POLE2 ORC6L ORC5L ORC2L PRIM2 POLE CDT1 MCM10 MCM8 MCM2 MCM3 MCM4 [NAME] | * | hsa-miR-185 (4.7e-10) hsa-miR-30b (8.4e-06) hsa-miR-643 (8.9e-05) hsa-miR-206 (0.0007) hsa-miR-30e-3p (0.002) hsa-miR-515-5p (0.0031)
REACTOME_MRNA_PROCESSING | NCBP2 NCBP1 ERCC3 ERCC2 GTF2H4 GTF2H3 RNMT CDK7 ADAR RNGTT POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] |  | hsa-miR-496 (1.5e-18) hsa-miR-1 (0.0017)
REACTOME_PI3K_CASCADE | FGF7 FGF9 FGF2 IRS2 IRS1 KL FGF10 FGFR1 PIK3R1 |  | hsa-miR-181c (8.9e-18) hsa-miR-181b (1.5e-14) hsa-miR-181a (4.8e-14) hsa-miR-145 (1.9e-09) hsa-miR-33 (1.8e-07) hsa-miR-424 (6.4e-07) hsa-miR-16 (4.4e-05) hsa-miR-15b (0.00012) hsa-miR-92 (0.00064) hsa-miR-183 (0.0018) hsa-miR-96 (0.0091)
REACTOME_A_THIRD_PROTEOLYTIC_CLEAVAGE_RELEASES_NICD | PSENEN APH1A PSEN1 PSEN2 |  | hsa-miR-205 (0.00014)
REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS | RAC1 ARF1 AP2S1 AP2M1 AP2B1 AP2A2 AP2A1 PACS1 AP1S3 AP1S1 AP1G1 DOCK2 ATP6V1H AP1M1 AP1M2 HCK AP1B1 PAK2 |  | hsa-miR-9 (5.7e-08) hsa-miR-299-3p (9.9e-08) hsa-miR-148a (2.4e-07) hsa-let-7b (3.6e-07) hsa-miR-34b (4.5e-06) hsa-miR-30e-5p (2.5e-05) hsa-miR-206 (4.3e-05) hsa-miR-1 (0.00015) hsa-miR-138 (0.0011) hsa-miR-148b (0.0016) hsa-miR-152 (0.0023) hsa-miR-30c (0.0044)
REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | NTHL1 OGG1 CCNO MPG TDG SMUG1 POLB |  | hsa-miR-30b (3.4e-06) hsa-let-7b (2.6e-05) hsa-miR-1 (4.3e-05) hsa-miR-320 (0.0092)
REACTOME_PHASE_II_CONJUGATION | MAT2B UGT2B28 UGT2B11 UGT2B10 UGP2 GSTA2 GSTA3 GSTA4 GSTA5 GLYAT ACSM2B SULT1C4 GSTM5 GCLC GSTP1 UGT1A8 UGT2A1 UGT2B4 UGT2B7 MGST1 MGST2 |  | hsa-miR-92 (1.4e-44) hsa-miR-142-5p (2.4e-30) hsa-miR-92b (3.2e-23) hsa-miR-367 (1.5e-16) hsa-miR-106b (1.7e-11) hsa-miR-485-3p (8.1e-09) hsa-miR-32 (2.6e-06) hsa-miR-25 (1.1e-05) hsa-miR-137 (5.8e-05) hsa-miR-20a (0.00093) hsa-miR-301 (0.0096)
REACTOME_VIRAL_MRNA_TRANSLATION | RPL18 [NAME] RPL13 RPL15 RPLP2 RPL10 FAU RPL11 [NAME] RPS14 [NAME] RPS11 RPS25 [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 RPL41 RPL35 RPL37 RPL38 RPL39 RPL30 RPL32 [NAME] RPL26 RPL27 RPL24 RPL29 RPL23 RPL22 [NAME] RPL9 RPL3 RPL5 RPL10A RPL7A RPL4 RPL37A RPS3 RPS3A RPS4X RPS15A RPL13A RPL27A | * | hsa-miR-142-5p (7.5e-133) hsa-miR-376b (3e-51) hsa-miR-218 (6.3e-28) hsa-miR-376a (1.7e-15) hsa-miR-137 (2e-08) hsa-miR-21 (8.1e-06) hsa-miR-135a (0.00052)
REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRON_CONTAINING_TRANSCRIPT | RAE1 NCBP2 NCBP1 SEH1L NUP188 TPR NUP155 NUP205 NUP214 NUP210 NUP85 NUP98 NUP93 U2AF2 SFRS9 NUP50 NUP62 NUPL1 RNPS1 |  | hsa-miR-125a (5.2e-13) hsa-miR-185 (5.2e-07) hsa-miR-514 (2.6e-05) hsa-miR-1 (0.00013) hsa-miR-129-3p (0.0022)
[NAME] | EHHADH ACSL1 SMARCD3 ME1 ABCA1 ANGPTL4 FABP4 ACADM CHD9 CYP4A11 CD36 NR1H3 SLC27A1 PPARA LPL UCP1 UGT2B4 SCP2 |  | hsa-miR-130a (2.1e-23) hsa-miR-142-5p (1.6e-18) hsa-miR-181c (3.7e-11) hsa-miR-19a (1.7e-06) hsa-miR-181a (7.8e-06) hsa-miR-25 (1.3e-05) hsa-miR-145 (5.3e-05) hsa-miR-20a (0.00019) hsa-miR-101 (0.00055) hsa-miR-183 (0.00057) hsa-miR-20b (0.0008) hsa-miR-218 (0.0023) hsa-miR-301 (0.0027) hsa-miR-181b (0.004)
REACTOME_METABOLISM_OF_NITRIC_OXIDE | [NAME] |  | hsa-miR-770-5p (0.00029)
REACTOME_BIOLOGICAL_OXIDATIONS | PTGS2 CYP1A1 CYP2B6 MAOA MAOB CYP17A1 CYP2C18 FMO2 FMO3 MAT2B ADH1C ADH1B ADH1A UGT2B28 UGT2B11 CYP2A6 UGT2B10 UGP2 CYP2U1 ALDH1A1 ADH4 GSTA2 GSTA3 GSTA4 GSTA5 CYP4A11 GLYAT CYP3A4 CYP3A5 CYP3A7 ACSM2B CYP4B1 CYP39A1 SULT1C4 ACSS2 GSTM5 PTGIS GCLC ALDH2 CYP11A1 GSTP1 UGT1A8 CYP26B1 UGT2A1 UGT2B4 UGT2B7 MGST1 MGST2 | * | hsa-miR-142-5p (8.9e-37) hsa-miR-25 (4e-23) hsa-miR-149 (3.6e-21) hsa-miR-20a (6.2e-20) hsa-miR-144 (7e-18) hsa-miR-485-3p (7.9e-18) hsa-miR-15b (2.2e-12) hsa-miR-92 (1.1e-09) hsa-miR-367 (1.6e-09) hsa-miR-137 (3e-08) hsa-miR-130a (3.1e-08) hsa-miR-130b (2e-05) hsa-miR-15a (2e-05) hsa-miR-92b (4e-05) hsa-miR-101 (0.00027) hsa-miR-106b (0.00049) hsa-miR-575 (0.002) hsa-miR-769-5p (0.0026) hsa-miR-20b (0.0047)
REACTOME_MYD88_CASCADE | MYD88 SIGIRR IRAK4 IRAK1 TIRAP |  | hsa-miR-142-3p (0.00011)
[NAME] | PFKFB3 ALDOC [NAME] |  | hsa-miR-19b (0.0015) hsa-miR-19a (0.0042)
REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | GSK3A GSK3B BAD PDPK1 MDM2 AKT1S1 TSC2 AKT1 |  | hsa-miR-142-3p (3.9e-05)
REACTOME_RNA_POL_II_CTD_PHOSPHORYLATION_AND_INTERACTION_WITH_CE | ERCC3 ERCC2 GTF2H4 GTF2H3 RNMT CDK7 RNGTT POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] |  | hsa-miR-496 (1.7e-05)
REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | AP2S1 AP2M1 NTRK1 AP2B1 AP2A2 AP2A1 DNAL4 CLTC |  | hsa-miR-125b (8e-06) hsa-miR-205 (0.00051) hsa-miR-125a (0.006)
REACTOME_AMINE_LIGAND_BINDING_RECEPTORS | HTR1B HTR5A HTR2A DRD2 DRD5 ADRA2A ADRA2C ADRA2B ADRA1B ADRA1A ADRB2 ADRB1 [NAME] |  | hsa-miR-23b (9.8e-12) hsa-miR-101 (1.1e-08) hsa-miR-218 (4.3e-08) hsa-miR-32 (8.4e-05) hsa-miR-424 (0.001)
REACTOME_M_G1_TRANSITION | E2F2 E2F3 ORC1L CDC6 ORC6L ORC5L ORC2L CDT1 PSMD14 PSMD13 PSMD11 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 MCM8 PSMD1 PSMD2 PSMD3 PSMD4 PSMD8 MCM2 MCM3 MCM4 [NAME] [NAME] | * | hsa-miR-186 (1.1e-42) hsa-miR-125b (1.4e-12) hsa-miR-802 (1.5e-12) hsa-miR-125a (3e-12) hsa-miR-146a (5.3e-12) hsa-miR-185 (2.1e-08) hsa-miR-200a (3.3e-07) hsa-miR-146b (4.5e-07) hsa-miR-30b (2.5e-06) hsa-miR-767-3p (8.4e-06) hsa-miR-555 (1.7e-05) hsa-miR-643 (2.8e-05) hsa-miR-30d (0.0002) hsa-miR-30c (0.00022) hsa-miR-515-5p (0.00039) hsa-miR-27b (0.0083)
REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | TSGA14 CSNK1D SSNA1 TUBG1 NDE1 TUBA4A NEK2 ALMS1 CEP250 CETN2 YWHAG CEP72 CEP78 CEP70 FGFR1OP TUBB2C PCNT AZI1 TUBB PLK4 PLK1 ODF2 CEP164 CKAP5 | * | hsa-miR-28 (4.3e-08) hsa-miR-185 (1.7e-07) hsa-miR-217 (2.3e-06) hsa-miR-125a (5.1e-05) hsa-miR-155 (0.00074) hsa-miR-30c (0.0034) hsa-miR-186 (0.0039) hsa-let-7g (0.007)
REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | TXN TXNRD1 AK2 NME4 NME1 RRM2 CTPS2 CTPS DTYMK GUK1 GSR | * | hsa-miR-372 (0.0043)
REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | ARFGEF2 CCT6A SKIV2L FBXW9 CCT2 [NAME] |  | hsa-miR-24 (0.0012)
REACTOME_HORMONE_BIOSYNTHESIS | PTGS2 HSD11B1 CYP17A1 DPEP2 HSD3B1 HSD17B3 LRP2 DDC TSHB STAR POMC PTGIS CYP11B1 TPO CYP11A1 LTA4H |  | hsa-miR-19a (2.6e-10) hsa-miR-19b (4.5e-09) hsa-miR-101 (3.3e-08) hsa-miR-149 (7.7e-07) hsa-miR-144 (3.9e-05) hsa-miR-142-5p (0.00042)
REACTOME_EGFR_DOWNREGULATION | EGFR SPRY2 SPRY1 |  | hsa-miR-142-5p (1.3e-07) hsa-miR-23b (4.7e-07) hsa-miR-323 (0.0053)
REACTOME_ELONGATION_AND_PROCESSING_OF_CAPPED_TRANSCRIPTS | CCAR1 PTBP1 DHX9 SF3B4 SF3B3 SF3B2 SSRP1 TXNL4A NCBP2 NCBP1 SNRPD3 SNRPD1 PRPF4 PRPF6 FUS SUPT16H CTDP1 TH1L ERCC3 ERCC2 [NAME] GTF2H4 GTF2H3 SUPT4H1 TCEB2 TCEB3 TCEB1 DDX23 SNRPA1 HNRNPU HNRNPL WHSC2 [NAME] SFRS2 ELL POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] CD2BP2 PAPOLA EFTUD2 SNRPB SNRPF SNRPE SNRPG CSTF3 CSTF2 RNPS1 SMC1A CSTF1 | * | hsa-miR-30b (6.1e-12) hsa-miR-496 (1.2e-08) hsa-miR-302b (5.7e-07) hsa-miR-302a (1.2e-05) hsa-miR-212 (0.0026) hsa-miR-24 (0.006) hsa-miR-372 (0.0076)
REACTOME_PP2A_MEDIATED_DEPHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS | PPP2CB PPP2R1B PFKFB3 [NAME] |  | hsa-miR-183 (1.7e-15) hsa-miR-130b (9.9e-15) hsa-miR-19a (6.2e-13) hsa-miR-301 (8.3e-06) hsa-miR-19b (1.9e-05) hsa-miR-130a (0.0029)
REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | MADCAM1 APBB1IP SOS1 FGA FGB JAM2 JAM3 VCAM1 COL4A3 RAPGEF3 LAMC3 [NAME] LAMB2 LAMB1 LAMA2 LAMA1 ICAM2 COL2A1 AMICA1 VTN ITGAE ITGB4 ITGB1 ITGB8 ITGA3 ITGA9 ITGA6 ITGA7 RAP1A RAP1B TLN1 RASGRP2 VWF |  | hsa-miR-181a (2.3e-06) hsa-miR-145 (5.5e-05) hsa-miR-92 (0.00013) hsa-miR-25 (0.00057) hsa-miR-367 (0.0012) hsa-miR-181c (0.0022) hsa-miR-20a (0.0039)
REACTOME_PEPTIDE_CHAIN_ELONGATION | RPL18 [NAME] RPL13 RPL15 RPLP2 RPL10 FAU RPL11 [NAME] RPS14 [NAME] RPS11 RPS25 [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 RPL41 RPL35 RPL37 RPL38 RPL39 RPL30 RPL32 [NAME] RPL26 RPL27 RPL24 RPL29 RPL23 RPL22 [NAME] RPL9 RPL3 RPL5 RPL10A RPL7A RPL4 RPL37A RPS3 RPS3A RPS4X RPS15A RPL13A RPL27A EEF1A1 | * | hsa-miR-142-5p (1.4e-84) hsa-miR-218 (7.7e-74) hsa-miR-376b (1e-35) hsa-miR-21 (3.8e-29) hsa-miR-376a (4.8e-27) hsa-miR-137 (3.2e-13) hsa-miR-543 (4.4e-12) hsa-miR-33 (2.6e-07) hsa-miR-135b (9.3e-06) hsa-miR-135a (4.8e-05) hsa-miR-33b (0.00096) hsa-miR-586 (0.0066)
REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS | HRAS GRIN2D MAPK1 CAMK4 PDPK1 CAMK2A RPS6KA1 [NAME] |  | hsa-miR-125b (3.9e-05) hsa-miR-125a (0.00099) hsa-miR-152 (0.004)
REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND | FEN1 RPA3 PCNA POLD4 POLD1 POLD2 |  | hsa-miR-154 (2.1e-05)
REACTOME_COMPLEMENT_CASCADE | [NAME] IGKC C8B C7 C9 [NAME] C1S |  | hsa-let-7e (0.00016)
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT | SLC20A1 SLC3A2 SLC13A2 SLC5A11 SLC1A4 SLC1A5 SLC1A2 SLC1A1 SLC43A2 SLC7A11 SLC41A2 SLC11A1 SLC31A1 SLC24A2 SLC24A6 SLC26A6 SLC39A10 SLC16A3 SLC5A3 SLC39A7 SLC39A6 SLC39A4 SLC39A3 SLC39A1 SLC9A8 SLC9A7 SLC9A4 SLC9A1 SLC4A8 SLC44A2 SLC44A4 SLC7A9 SLC7A5 SLC7A7 SLC2A8 SLC2A6 SLC2A1 SLC6A13 SLC12A1 SLC36A1 SLC12A6 SLC12A7 SLC2A13 SLC2A10 SLC16A10 SLC15A3 SLC6A1 SLC4A2 SLC4A1 SLC38A1 SLC38A5 SLC30A1 [NAME] SLC17A8 SLC6A9 SLC6A5 SLC6A6 |  | [NAME] (0.001)
REACTOME_GPCR_LIGAND_BINDING | AGTR1 AGTR2 [NAME] WNT10B GPER SSTR1 PTH2R NPY5R PENK AVPR1A HTR5A GIP [NAME] GNG13 GNG11 CCL28 CCL27 CCL23 CCL21 CCBP2 CCL19 [NAME] P2RY12 P2RY14 GNG10 NMBR HTR2A CXCL12 GALR1 GPR44 RGR NTSR2 CCL2 ADORA2B [NAME] CX3CL1 ADRA2A ADRA2C ADRA1B XCL2 RHO GPR109B GABBR1 CCRL1 PTGER2 PTGER3 PTGER4 ADRB2 ADRB1 CHRM3 GPR17 VIP CCK TAC1 OXTR PF4 ANXA1 FZD10 EDN3 EDN1 GPR120 GPBAR1 PPBP HTR7 CX3CR1 PRLHR POMC NPY TAS1R1 EDNRB PROK2 GRM3 ADM PROK1 GRM7 PTGDR CXCL1 AVPR2 OPN1LW CXCL3 CXCL2 NMB CXCL6 [NAME] PTGFR FZD5 FZD4 [NAME] PTCH1 [NAME] PTHLH DARC CNR1 [NAME] CXCR7 NPFF RAMP2 SMO WNT11 CALCR NTS CRH |  | hsa-miR-25 (2.8e-10) hsa-miR-20a (1.2e-07) hsa-miR-145 (9.8e-07) hsa-miR-92b (1.1e-06) hsa-miR-92 (0.00019) hsa-miR-181a (0.00023) hsa-miR-130b (0.00044) hsa-miR-144 (0.0012) hsa-miR-586 (0.0013) hsa-miR-424 (0.0019) hsa-miR-323 (0.0025) hsa-miR-19a (0.0026) hsa-miR-367 (0.0066) hsa-miR-27a (0.0069)
REACTOME_P53_INDEPENDENT_DNA_DAMAGE_RESPONSE | CDC25A [NAME] PSMD11 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] | * | hsa-miR-186 (1.8e-13) hsa-miR-802 (2.3e-13) hsa-miR-146b (2.4e-10) hsa-miR-146a (9.4e-09) hsa-miR-515-5p (0.00058) hsa-miR-765 (0.00072) hsa-miR-620 (0.00097) hsa-miR-555 (0.0029) hsa-miR-30d (0.0054) hsa-let-7c (0.0098)
REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | RAE1 SEH1L NUP188 TPR NUP155 NUP205 NUP214 NUP210 XPO1 NUP85 NUP98 NUP93 NUP50 NUP62 NUPL1 | * | hsa-miR-185 (1.2e-06) hsa-miR-514 (2.8e-05) hsa-miR-129-3p (0.00017) hsa-miR-125a (0.00033) hsa-miR-142-3p (0.0018) hsa-miR-186 (0.0052) hsa-miR-125b (0.0099)
REACTOME_NUCLEOTIDE_EXCISION_REPAIR | LIG1 RAD23B XAB2 DDB1 RPA3 ERCC3 ERCC4 ERCC1 ERCC2 PCNA GTF2H4 GTF2H3 POLE2 POLD4 POLD1 POLD2 CDK7 POLE RFC5 RFC3 RFC4 RFC2 POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] |  | hsa-miR-496 (6.1e-06) hsa-miR-217 (0.00025) hsa-miR-302b (0.0023) hsa-miR-93 (0.0027)
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS | A2M SGMS2 EHHADH CH25H HSD11B1 HACL1 GPD1 ACACB HMGCS2 HSD3B1 ACSL1 HSD17B3 PHYH APOA4 SMARCD3 HADH ME1 ABCA1 ANGPTL4 FABP4 ACOX2 ACADM ACADS ACADL ACADVL GPAM CHD9 SLCO1A2 CYP4A11 SLCO1B1 STAR APOB LCAT CD36 [NAME] NR1H3 SCD ABCG5 SLC27A1 PPARA CYP39A1 AGPAT4 HSPG2 PPP1CC CAV1 ALB LPL UCP1 SGPP1 MGLL CYP11A1 PRKD1 [NAME] LIPC SCP2 LIPE |  | hsa-miR-183 (8.6e-09) hsa-miR-33 (7.1e-08) hsa-miR-181b (2.8e-07) hsa-miR-218 (6.3e-07) hsa-miR-20a (1.9e-06) hsa-miR-130a (1.9e-06) hsa-miR-142-5p (1.2e-05) hsa-miR-25 (0.00021) hsa-miR-181c (0.00026) hsa-miR-145 (0.00028) hsa-miR-424 (0.00034) hsa-miR-181a (0.00082) hsa-miR-19b (0.00092) hsa-miR-19a (0.0029)
REACTOME_CRMPS_IN_SEMA3A_SIGNALING | FES DPYSL2 SEMA3A FYN |  | hsa-miR-145 (3.3e-17) hsa-miR-181c (7.6e-09) hsa-miR-181b (2.7e-07) hsa-miR-92 (2.3e-06) hsa-miR-32 (0.0025) hsa-miR-586 (0.004)
REACTOME_MRNA_SPLICING | CCAR1 PTBP1 DHX9 SF3B4 SF3B2 TXNL4A NCBP2 NCBP1 SNRPD3 SNRPD1 PRPF6 FUS LSM2 DDX23 [NAME] POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] PAPOLA EFTUD2 SNRPB SNRPF SNRPE SNRPG CSTF3 CSTF2 RNPS1 | * | hsa-miR-200a (8.3e-06) hsa-miR-302a (0.00011) hsa-miR-30b (0.00033) hsa-miR-1 (0.00039) hsa-miR-212 (0.00055) hsa-miR-331 (0.00057) hsa-miR-302b (0.00059) hsa-miR-206 (0.002) hsa-miR-194 (0.005) hsa-miR-125a (0.0056)
REACTOME_GLUCOSE_METABOLISM | PCK1 PC UGP2 GYG2 PGM1 PFKFB3 ALDOC [NAME] PHKB PYGM PYGL [NAME] |  | hsa-miR-19b (9.8e-13) hsa-miR-367 (4.1e-09) hsa-miR-92 (2e-06) hsa-miR-133a (4.5e-05) hsa-miR-25 (0.00062) hsa-miR-130b (0.0012) hsa-miR-32 (0.0018) hsa-miR-19a (0.0021) hsa-miR-770-5p (0.0027) hsa-miR-92b (0.0044)
REACTOME_MICRORNA_BIOGENESIS | XPO5 DICER1 TARBP2 POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] | * | hsa-let-7b (6.8e-18) hsa-miR-125b (3.5e-08) hsa-miR-148b (1.3e-07) hsa-miR-122a (0.00012) hsa-miR-148a (0.00032) hsa-miR-152 (0.0038)
REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | AGTR2 [NAME] GPER SSTR1 GNAI1 NPY5R PENK GNAZ HTR5A [NAME] GNG13 GNG11 CCL28 CCL27 CCL23 CCL21 CCL19 [NAME] P2RY12 P2RY14 GNG10 CXCL12 GALR1 GPR44 RGR DRD2 ADRA2A ADRA2C RHO GPR109B GABBR1 PTGER3 GPR17 PF4 ANXA1 ADCY3 ADCY4 ADCY8 ADCY5 ADCY6 PPBP POMC NPY CXCL1 OPN1LW CXCL3 CXCL2 CXCL6 CNR1 CXCR7 |  | hsa-miR-335 (1.6e-29) hsa-miR-181c (1.3e-06) hsa-miR-19b (3.9e-06) hsa-miR-25 (5.8e-06) hsa-miR-142-5p (2.3e-05) hsa-miR-92b (6.1e-05) hsa-miR-375 (0.00012) hsa-miR-367 (0.00014) hsa-miR-181b (0.00014) hsa-miR-218 (0.00016) hsa-miR-101 (0.0015) hsa-miR-144 (0.0017) hsa-miR-135b (0.0017) hsa-miR-19a (0.0019) hsa-miR-485-3p (0.0078) hsa-miR-23b (0.0081)
REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | SLC47A1 SLC47A2 SLC16A7 |  | hsa-miR-29b (0.0068)
REACTOME_DOWNSTREAM_EVENTS_IN_GPCR_SIGNALING | AGTR1 AGTR2 [NAME] ROCK1 GPER SSTR1 GNAI1 PTH2R NPY5R PENK AVPR1A GNAZ PDE11A HTR5A ARHGEF4 GIP ARHGEF6 ARHGEF17 [NAME] GNG13 GNG11 CCL28 CCL27 CCL23 DGKB CCL21 SOS1 PDE1A PLEKHG5 SOS2 CCL19 NPY1R DGKI CCL16 P2RY12 PDE2A P2RY14 GNG10 NMBR HTR2A PDE3B CXCL12 GALR1 GPR44 RGR PDE4C NTSR2 RASGRF2 ADORA2B [NAME] ADRA2C PDE7B ADRA1B XCL2 RHO GPR109B GABBR1 RHOA PDE8B PDE8A PTGER2 PTGER3 PTGER4 ADRB2 ADRB1 CHRM3 GPR17 VIP CCK TAC1 OXTR PF4 ANXA1 ADCY3 EDN3 ADCY4 ADCY8 ADCY5 EDN1 ADCY6 GPBAR1 PPBP HTR7 POMC NPY GRK5 EDNRB PROK2 ADM PROK1 PTGDR CXCL1 AVPR2 OPN1LW CXCL3 CXCL2 NMB CXCL6 PTGFR ITPR1 ITPR2 [NAME] TIAM2 PTHLH KALRN CNR1 [NAME] TAAR9 CXCR7 GEFT MGLL PLCB1 AKT3 NPFF RAMP3 RAMP2 CALCR PIK3R1 NTS CRH |  | hsa-miR-145 (2.3e-14) hsa-miR-335 (5.4e-06) hsa-miR-181c (1.1e-05) hsa-miR-19a (5e-05) hsa-miR-181a (0.00012) hsa-miR-27a (0.0017) hsa-miR-32 (0.0017) hsa-miR-25 (0.0023) hsa-miR-424 (0.0073) hsa-miR-144 (0.0073) hsa-miR-106a (0.0083) hsa-miR-92b (0.0085) hsa-miR-20a (0.0097)
REACTOME_ACTIVATION_OF_CHAPERONES_BY_IRE1_ALPHA | DNAJC3 DNAJB11 PDIA6 NFYA HSPA5 |  | hsa-miR-30b (0.00029)
REACTOME_CD28_CO_STIMULATION | THEM4 PDPK1 GRB2 CD80 TRIB3 CDC42 SRC AKT1 PAK2 PAK1 |  | hsa-miR-1 (0.00072) hsa-let-7b (0.0035)
REACTOME_CLASS_B2_SECRETIN_FAMILY_RECEPTORS | [NAME] WNT10B PTH2R GIP GNG13 GNG11 GNG10 VIP FZD10 ADM FZD9 FZD8 FZD1 FZD5 FZD4 FZD7 PTCH1 [NAME] PTHLH RAMP3 RAMP2 SMO WNT11 CALCR CRH |  | hsa-miR-145 (1.9e-09) hsa-miR-32 (0.00015) hsa-miR-20a (0.00067) hsa-miR-218 (0.0017) hsa-miR-144 (0.0025) hsa-miR-181c (0.0028) hsa-miR-367 (0.0052) hsa-miR-181a (0.0052)
REACTOME_REGULATION_OF_INSULIN_SECRETION | CACNB3 FH GNGT1 GNGT2 NDUFB11 NDUFB10 SDHC GNA15 NDUFAB1 CYC1 UQCRQ GCK MDH2 ALDOA [NAME] ATP5H [NAME] COX8A UQCRC1 PFKL GAPDH GNG5 NDUFA13 NDUFA11 GNB2 GNB1 GNAS GNB3 PRKAR2A IDH3G SLC2A1 ATP5J2 PRKAR1B [NAME] CACNA1D NDUFS6 NDUFS8 NDUFS3 NDUFS2 ATP5G1 PFKFB4 PFKFB2 TPI1 COX6B1 COX6A1 ITPR3 PGK1 KCNS3 PLCB3 PLCB2 NDUFC2 NDUFC1 NDUFB4 NDUFB9 NDUFB1 NDUFB2 ENO2 NDUFA2 NDUFA3 NDUFA8 NDUFA6 NDUFA7 |  | hsa-miR-185 (0.0015)
REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | [NAME] |  | hsa-miR-92 (0.00023) hsa-miR-32 (0.002)
REACTOME_G_PROTEIN_ACTIVATION | [NAME] GNAZ GNG13 GNG11 POMC |  | hsa-miR-19b (2.3e-11) hsa-miR-19a (9.1e-09) hsa-miR-485-3p (5.7e-08) hsa-miR-218 (3.7e-06)
REACTOME_MTORC1_MEDIATED_SIGNALLING | RPS6 EIF4B |  | hsa-miR-145 (1e-05)
REACTOME_RESOLUTION_OF_AP_SITES_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | LIG3 NTHL1 OGG1 CCNO MPG XRCC1 TDG SMUG1 POLB | * | hsa-miR-1 (1.9e-09) hsa-miR-125a (0.00017) hsa-miR-30d (0.0081)
REACTOME_PROSTANOID_HORMONES | PTGS2 PTGIS |  | hsa-miR-101 (1.9e-06) hsa-miR-149 (7e-05)
REACTOME_INSULIN_SYNTHESIS_AND_SECRETION | RPL18 [NAME] RPL13 RPL15 RPLP2 RPL10 FAU RPL11 [NAME] RPS14 [NAME] RPS11 GNAI1 RPS25 [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 RPL41 [NAME] [NAME] SNAP25 RPL26 RPL27 RPL24 RPL29 RPL22 [NAME] RPL35A VAMP2 RPL6 RPL9 RPL3 RPL5 RPL10A [NAME] RPL37A RPS3 RPS3A STXBP1 RPS4X RPS15A RPL13A [NAME] |  | hsa-miR-485-3p (6e-21) hsa-miR-218 (1.8e-19) hsa-miR-142-5p (1.7e-18) hsa-miR-92 (6.5e-17) hsa-miR-19a (9.7e-09) hsa-miR-376b (2.7e-08) hsa-miR-15b (6.7e-08) hsa-miR-130a (3.3e-07) hsa-miR-19b (1.2e-05) hsa-miR-137 (1.6e-05) hsa-miR-376a (0.00058) hsa-miR-21 (0.0016)
REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL | HRAS NRAS PPIL2 OLR1 [NAME] SLC16A3 MMP1 ITGAL GRB2 ITGAX FN1 SHC1 PIK3R2 COL1A1 TREM1 PTPN6 |  | hsa-let-7f (0.0031) hsa-miR-217 (0.0096)
REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PREREPLICATIVE_COMPLEX | E2F2 E2F3 ORC1L CDC6 ORC5L ORC2L CDT1 |  | [NAME] (1.3e-11) hsa-miR-185 (4.5e-08) hsa-miR-194 (0.0022) hsa-miR-30b (0.0023) hsa-miR-34a (0.0051)
REACTOME_TAT_MEDIATED_HIV1_ELONGATION_ARREST_AND_RECOVERY | CTDP1 TH1L RDBP TCEB2 TCEB3 TCEB1 ELL POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] | * | hsa-miR-30b (2.9e-06) hsa-miR-24 (0.00016) hsa-miR-9 (0.0077)
REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | ADSS GART IMPDH1 ATIC PPAT GMPS |  | hsa-miR-125b (0.0059)
REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | SNAP25 VAMP2 SLC1A7 STXBP1 GLS SLC17A7 |  | hsa-miR-181c (1.1e-07) hsa-miR-23b (2.6e-07) hsa-miR-218 (0.00028) hsa-miR-20a (0.00091)
REACTOME_HIV1_TRANSCRIPTION_INITIATION | TAF10 TAF13 TAF12 ERCC2 GTF2H4 GTF2H3 GTF2E1 TAF1 TAF4 TAF5 GTF2A1 CDK7 POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] |  | [NAME] (1.3e-12) hsa-miR-496 (6.2e-10) hsa-miR-148b (2.5e-05) hsa-let-7f (0.00031) hsa-let-7b (0.0013) hsa-miR-128a (0.0022) hsa-miR-200a (0.0025) hsa-miR-132 (0.003) hsa-miR-320 (0.0059)
REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING | GNGT1 GNGT2 PDPK1 PIK3R5 GNG5 GNB2 GNB1 GNB3 AKT1 PLCB3 PLCB2 |  | hsa-let-7b (0.0003)
REACTOME_SIGNAL_ATTENUATION | IRS2 IRS1 |  | hsa-miR-92 (9.1e-15) hsa-miR-145 (2.2e-11) hsa-miR-181c (5.2e-11) hsa-miR-183 (0.00017) hsa-miR-181b (0.00091)
REACTOME_TOLL_RECEPTOR_CASCADES | [NAME] NFKBIB MAPKAPK3 MAPKAPK2 IKBKE IKBKG IKBKB MYD88 SIGIRR IRAK4 IRAK1 IRF7 IRF3 MAP2K7 MAP2K2 RPS6KA1 [NAME] ELK1 |  | hsa-miR-132 (0.0001)
REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA | RAE1 CCAR1 PTBP1 DHX9 SF3B4 SF3B2 TXNL4A NCBP2 NCBP1 SNRPD3 SNRPD1 PRPF6 FUS SEH1L NUP188 TPR NUP155 LSM2 NUP205 NUP214 NUP210 DDX23 [NAME] NUP85 CPSF2 CPSF1 NUP98 NUP93 U2AF2 SFRS9 NUP50 NUP62 POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] CD2BP2 PAPOLA EFTUD2 NUPL1 SNRPB SNRPF SNRPE SNRPG CSTF3 CSTF2 RNPS1 CSTF1 | * | hsa-miR-125a (1.4e-11) hsa-miR-30a-5p (9.6e-05) hsa-miR-155 (0.00012) hsa-miR-30b (0.00015) hsa-miR-302b (0.00016) hsa-miR-302a (0.0013) hsa-miR-125b (0.0034) hsa-miR-93 (0.006) hsa-miR-331 (0.0069) hsa-miR-129-3p (0.0073) hsa-miR-206 (0.0088)
REACTOME_METAL_ION_SLC_TRANSPORTERS | SLC41A2 SLC11A1 SLC31A1 SLC39A10 SLC39A7 SLC39A6 SLC39A4 SLC39A3 SLC39A1 SLC30A1 [NAME] |  | hsa-miR-1 (1.6e-09) hsa-miR-217 (2e-06)
REACTOME_GLUCOSE_TRANSPORT | RAE1 GCK SEH1L NUP188 TPR NUP155 NUP205 HK1 NUP214 NUP210 HK3 SLC2A1 NUP85 NUP98 NUP93 NUP50 NUP62 NUPL1 |  | hsa-miR-185 (3.4e-07) hsa-miR-514 (3.4e-06) hsa-miR-148b (6.9e-05) hsa-miR-125a (6.9e-05) hsa-miR-125b (0.00032) hsa-miR-148a (0.00047) hsa-miR-34a (0.0069)
REACTOME_TELOMERE_MAINTENANCE | LIG1 FEN1 HIST1H4K HIST1H4A HIST1H4B HIST1H4E HIST1H4F HIST1H4I HIST1H4J HIST1H4H H2BFS HIST3H2BB HIST3H3 RPA3 HIST2H2AA3 [NAME] HIST1H2BM HIST1H2BN HIST1H2BK HIST1H2BL HIST1H2BI HIST1H2BJ PCNA HIST2H2AC HIST2H2BE RUVBL2 RUVBL1 HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE [NAME] HIST1H2BB HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2AK POLE2 PRIM2 H2AFZ H2AFX POLE RFC4 RFC2 | * | hsa-miR-802 (1.1e-35) hsa-miR-154 (1e-29) hsa-miR-1 (9e-28) hsa-miR-24 (4.8e-20) hsa-miR-610 (1e-12) hsa-miR-212 (7.2e-10) hsa-miR-217 (4e-08) hsa-miR-515-5p (5.7e-06) hsa-miR-9 (1e-05) hsa-miR-544 (0.00012) hsa-miR-659 (0.00073) hsa-miR-584 (0.0016)
REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | HRAS BRAF MAPK1 NRAS KRAS YWHAB MAP2K2 |  | hsa-let-7f (9.2e-06) hsa-miR-28 (5.9e-05) hsa-miR-148b (0.00011) hsa-miR-217 (0.00052) hsa-let-7g (0.00062) hsa-miR-148a (0.0016) hsa-miR-30b (0.0017) hsa-let-7b (0.0055) hsa-miR-155 (0.0067)
REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES | SULT4A1 SULT1A1 SULT1A2 SULT1B1 SULT1E1 SULT1C4 SULT1C2 SULT2B1 SULT2A1 |  | hsa-miR-101 (0.0015)
REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | MAML3 MAML2 NOTCH2 NOTCH4 RBPJ SNW1 |  | hsa-miR-21 (0.0014) hsa-miR-34c (0.0022)
REACTOME_RHO_GTPASE_CYCLE | [NAME] RAC3 RAC1 ARHGEF18 ARHGEF16 ARHGEF11 FGD3 ARHGDIA [NAME] MYO9B MCF2L GDI1 RHOBTB1 G3BP2 ARHGAP30 PIK3R2 SYDE2 ARHGAP11A ARHGEF2 RASGRF1 VAV3 VAV2 CDC42 RHOC RHOD RHOF RHOG INPP5B DEPDC1B DEPDC7 DEPDC1 TRIO GMIP RHOT2 ECT2 RACGAP1 GRLF1 |  | hsa-miR-186 (0.0047) hsa-miR-185 (0.0066)
REACTOME_STEROID_HORMONES | HSD11B1 GC CYP17A1 HSD3B1 HSD17B3 LRP2 CUBN CYP24A1 STAR LGMN STARD6 CYP19A1 CYP11B1 CYP11A1 |  | hsa-miR-19a (0.0007) hsa-miR-101 (0.0013) hsa-miR-19b (0.0081)
REACTOME_NUCLEAR_IMPORT_OF_REV_PROTEIN | RAE1 SEH1L NUP188 TPR NUP155 NUP205 NUP214 NUP210 NUP85 NUP98 NUP93 NUP50 NUP62 NUPL1 KPNB1 | * | hsa-miR-185 (3.3e-12) hsa-miR-148b (3.1e-11) hsa-miR-125a (3.4e-10) hsa-miR-125b (9.3e-07) hsa-miR-148a (1.3e-05) hsa-miR-129-3p (0.00078) hsa-miR-514 (0.0021)
REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | RAE1 GCK SEH1L NUP188 TPR NUP155 NUP205 NUP214 NUP210 NUP85 NUP98 NUP93 NUP50 NUP62 NUPL1 | * | hsa-miR-185 (8.9e-10) hsa-miR-129-3p (5.8e-07) hsa-miR-125a (2.2e-05) hsa-miR-514 (0.0015)
[NAME] | RAE1 RAC1 ARF1 [NAME] AP2B1 SEH1L AP2A2 PACS1 PPIA NUP188 RANBP1 TPR NUP155 RANGAP1 AP1S3 AP1S1 NUP205 NUP214 NUP210 TCEB2 TCEB1 XPO1 AP1G1 BTRC DOCK2 ATP6V1H NUP85 [NAME] HCK NUP50 NUP62 AP1B1 PSMD14 PSMD13 PSMD12 PSMD11 NUPL1 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 PAK2 PSMD1 PSMD2 PSMD3 PSMD4 KPNB1 PSMD8 [NAME] PSMB10 | * | hsa-miR-186 (6.4e-33) hsa-miR-802 (1.8e-20) hsa-miR-148a (4.1e-14) hsa-miR-152 (1.4e-12) hsa-miR-34a (1.4e-09) hsa-miR-146b (7.5e-08) hsa-miR-132 (1.3e-06) hsa-miR-328 (5.7e-06) hsa-miR-93 (8.1e-06) hsa-miR-155 (1.2e-05) hsa-miR-30b (0.00011) hsa-miR-148b (0.00021) hsa-let-7e (0.00076) hsa-miR-620 (0.0013) hsa-miR-30c (0.002) hsa-let-7f (0.0021) hsa-miR-125b (0.0026) hsa-miR-146a (0.0029) hsa-miR-555 (0.0031) hsa-miR-1 (0.0036) hsa-miR-299-3p (0.0041) hsa-miR-320 (0.0047) hsa-miR-185 (0.0054)
REACTOME_MEMBRANE_TRAFFICKING | ARF1 [NAME] ARFGAP1 DNASE2 GAK TPD52 RAB5C PREB COPA CLTC COPG COPE TGOLN2 AP1S3 COPB2 AP1S1 COPB1 STX4 DNM2 AP1G1 SEC13 SEC24C SEC24D M6PR [NAME] AP1M1 AP1M2 AP1B1 AP3B1 COPZ1 NAPA CTSZ | * | [NAME] (1.6e-17) hsa-miR-152 (2e-16) hsa-miR-320 (2.2e-07) hsa-miR-185 (5.7e-07) hsa-miR-299-3p (8.5e-05) hsa-miR-204 (0.00011) hsa-miR-125b (0.0002) hsa-miR-9 (0.00059) hsa-miR-30c (0.00079) hsa-miR-138 (0.0016) hsa-miR-98 (0.0036) hsa-miR-194 (0.0059)
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS | AGTR1 AGTR2 GPER SSTR1 NPY5R PENK AVPR1A HTR5A [NAME] CCL28 CCL27 CCL23 CCL21 CCBP2 CCL19 [NAME] P2RY12 P2RY14 NMBR HTR2A CXCL12 GALR1 GPR44 RGR NTSR2 CCL2 ADORA2B [NAME] CX3CL1 ADRA2A ADRA2C ADRA1B XCL2 RHO GPR109B CCRL1 PTGER2 PTGER3 PTGER4 ADRB2 [NAME] TAC1 OXTR PF4 ANXA1 EDN3 EDN1 GPR120 GPBAR1 PPBP HTR7 CX3CR1 PRLHR POMC NPY EDNRB PROK2 PROK1 PTGDR CXCL1 AVPR2 OPN1LW CXCL3 CXCL2 NMB CXCL6 PTGFR DARC CNR1 [NAME] NPFF NTS |  | hsa-miR-367 (2.4e-29) hsa-miR-218 (8.1e-24) hsa-miR-145 (3.6e-22) hsa-miR-23b (1.2e-10) hsa-miR-181c (2.1e-10) hsa-miR-181a (2.3e-09) hsa-miR-32 (3.2e-09) hsa-miR-23a (1.9e-08) hsa-miR-375 (1.8e-06) hsa-miR-25 (8.9e-05) hsa-miR-142-5p (0.00011) hsa-miR-19a (0.00038) hsa-miR-323 (0.00046) hsa-miR-33 (0.00068) hsa-miR-424 (0.0023) hsa-miR-16 (0.0062) hsa-miR-92 (0.007)
REACTOME_PLC_GAMMA1_SIGNALLING | [NAME] PRKAR2B ADCY3 [NAME] ITPR1 ITPR2 [NAME] |  | hsa-miR-19b (8.3e-12) hsa-miR-92 (8e-11) hsa-miR-770-5p (5.3e-05) hsa-miR-32 (0.00026) hsa-miR-19a (0.00039) hsa-miR-218 (0.00041) hsa-miR-92b (0.0013) hsa-miR-335 (0.0069) hsa-miR-25 (0.009)
REACTOME_G1_S_TRANSITION | DBF4 [NAME] E2F3 FBXO5 RPA3 TYMS ORC1L PCNA CCNE2 CCNE1 CDC7 CDC6 RRM2 POLA1 POLA2 CCNB1 POLE2 ORC6L CDK7 ORC5L ORC2L CDC25A PRIM2 POLE CDT1 PSMD14 PSMD13 PSMD11 MCM10 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC2 MCM8 PSMD1 PSMD2 PSMD3 PSMD4 PSMD8 MCM2 MCM3 MCM4 MCM6 [NAME] | * | hsa-miR-30b (6.1e-25) hsa-miR-148a (1.9e-22) hsa-miR-146b (2.7e-22) hsa-miR-515-5p (6.1e-16) hsa-miR-152 (9.9e-13) hsa-miR-802 (6.8e-12) hsa-miR-186 (3.8e-11) hsa-miR-496 (9e-09) hsa-miR-767-3p (1.9e-08) hsa-miR-328 (7.5e-08) hsa-miR-146a (5.2e-07) hsa-miR-200a (1.9e-06) hsa-miR-34a (5.7e-06) hsa-let-7i (1.2e-05) hsa-miR-555 (1.3e-05) hsa-miR-125a (8e-05) hsa-miR-503 (0.00078) hsa-miR-125b (0.0012) hsa-miR-1 (0.0015) hsa-miR-765 (0.0016) hsa-miR-30c (0.0019) hsa-miR-148b (0.0034) hsa-miR-643 (0.0073) hsa-miR-185 (0.0083)
REACTOME_SIGNALING_BY_NOTCH | FURIN PSENEN APH1A PSEN1 PSEN2 |  | hsa-miR-185 (0.00033)
REACTOME_SIGNALLING_TO_RAS | HRAS MAPK1 NRAS RALA MAPKAPK3 MAPKAPK2 [NAME] MAPK13 SRC |  | hsa-let-7f (3.4e-15) hsa-miR-217 (2.5e-14) hsa-miR-148a (1.1e-13) hsa-miR-148b (6.3e-11) hsa-miR-30b (0.00064) hsa-miR-30e-5p (0.0062)
REACTOME_REPAIR_SYNTHESIS_OF_PATCH_27_30_BASES_LONG_BY_DNA_POLYMERASE | RPA3 PCNA POLE2 POLD4 POLD1 POLD2 POLE RFC5 RFC3 RFC4 RFC2 |  | hsa-miR-154 (4.6e-05) hsa-miR-134 (0.0052) hsa-miR-217 (0.0097)
REACTOME_S_PHASE | LIG1 FEN1 RPA3 CCNA2 ORC1L PCNA CCNE2 CCNE1 CDC6 CCND1 POLA1 POLA2 POLE2 ORC6L GINS1 GINS2 GINS4 POLD4 POLD1 POLD2 CDK7 CDK2 ORC5L ORC2L CDC25A CDC25B PRIM2 POLE RFC5 RFC3 RFC4 RFC2 CDT1 PSMD14 PSMD13 PSMD12 PSMD11 PSMA6 PSMA4 PSMA3 FZR1 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 MCM8 PSMD1 PSMD2 PSMD3 PSMD4 PSMD8 MCM2 MCM3 MCM4 [NAME] [NAME] PSMB10 | * | hsa-miR-30b (4.5e-47) hsa-miR-148a (4e-43) hsa-miR-186 (1.4e-25) hsa-miR-802 (4.7e-25) hsa-miR-146b (2.7e-19) hsa-miR-152 (8.9e-16) hsa-miR-148b (1.7e-12) hsa-let-7a (8.8e-11) hsa-let-7f (1e-08) hsa-miR-555 (3e-08) hsa-miR-30e-3p (1.1e-07) hsa-miR-146a (2.7e-05) hsa-miR-765 (4.4e-05) hsa-miR-328 (5.7e-05) hsa-miR-767-3p (6.5e-05) hsa-miR-93 (8.3e-05) hsa-miR-132 (0.00011) hsa-miR-30c (0.0011) hsa-miR-496 (0.0018) hsa-let-7i (0.0022) hsa-miR-1 (0.0053) hsa-miR-610 (0.0066) hsa-miR-515-5p (0.0092)
REACTOME_OTHER_SEMAPHORIN_INTERACTIONS | SEMA5A SEMA6A SEMA6D |  | hsa-miR-145 (9.7e-19) hsa-miR-15b (2.3e-09) hsa-miR-19b (2.4e-09) hsa-miR-23b (3e-08) hsa-miR-375 (3.4e-05) hsa-miR-218 (3.9e-05) hsa-miR-19a (0.0001) hsa-miR-183 (0.0077)
REACTOME_E2F_TRANSCRIPTIONAL_TARGETS_AT_G1_S | [NAME] FBXO5 TYMS ORC1L PCNA CCNE1 CDC6 RRM2 POLA1 CDC25A CDT1 | * | hsa-miR-1 (9.1e-16) hsa-miR-148a (4.4e-15) hsa-miR-30d (3.1e-07) hsa-miR-152 (2.3e-05) hsa-let-7i (3.9e-05) hsa-miR-30b (9.5e-05) hsa-let-7b (0.0012) hsa-miR-342 (0.0022) hsa-let-7f (0.0037) hsa-let-7e (0.0051)
REACTOME_CDC20_PHOSPHO_APC_MEDIATED_DEGRADATION_OF_CYCLIN_A | ANAPC2 ANAPC7 UBE2C BUB3 MAD2L1 CDC20 PSMD14 PSMD13 PSMD11 PSMA6 PSMA4 PSMA3 ANAPC11 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] | * | hsa-miR-186 (1.5e-14) hsa-miR-146a (1.5e-09) hsa-miR-802 (2.6e-08) hsa-miR-146b (1.9e-05) hsa-miR-620 (0.0003) hsa-miR-555 (0.00041) hsa-miR-515-5p (0.0016) hsa-miR-765 (0.0084)
REACTOME_GRB2_EVENTS_IN_EGFR_SIGNALING | HRAS MAPK1 NRAS KRAS [NAME] MAP2K2 |  | hsa-miR-30b (1.1e-18) hsa-miR-148a (2e-06) hsa-miR-152 (2.2e-05) hsa-miR-148b (0.00048) hsa-let-7f (0.0015) hsa-miR-217 (0.0054) hsa-miR-132 (0.0088) hsa-miR-28 (0.0096)
REACTOME_TRANSCRIPTION_OF_THE_HIV_GENOME | TAF10 TAF13 TAF12 SSRP1 NCBP2 NCBP1 SUPT16H CTDP1 TH1L ERCC3 ERCC2 RDBP GTF2H4 GTF2H3 SUPT4H1 TCEB2 TCEB3 [NAME] TAF4 TAF5 WHSC2 GTF2A1 CDK7 ELL RNGTT POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] | * | hsa-miR-496 (6.6e-18) hsa-miR-9 (4.2e-11) hsa-miR-132 (1.1e-10) hsa-miR-148b (4e-09) hsa-miR-204 (6.2e-08) hsa-miR-302b (6.6e-06) hsa-miR-320 (1.6e-05) hsa-let-7f (4.9e-05) hsa-miR-299-3p (0.00041) hsa-miR-302c (0.00041) hsa-miR-152 (0.00051) hsa-miR-148a (0.0006) hsa-miR-302a (0.0019) hsa-let-7b (0.0035) hsa-miR-30b (0.0036) hsa-miR-34a (0.0042) hsa-miR-24 (0.0043)
REACTOME_TRANSCRIPTION | TAF10 TAF13 TAF12 SSRP1 NCBP2 [NAME] HIST1H4K HIST1H4A HIST1H4B HIST1H4E HIST1H4F HIST1H4C HIST1H4D HIST1H4I HIST1H4J HIST1H4H HIST1H3J EHMT2 HIST1H3A HIST1H3B HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I GTF3C5 GTF3C2 GTF3C1 GTF3C4 POLRMT SUPT16H H2BFS HIST3H2BB CTDP1 UBTF TH1L ERCC2 HIST2H2AA3 HIST1H2BO HIST1H2BM HIST1H2BN HIST1H2BK HIST1H2BL HIST1H2BI HIST1H2BJ RDBP H3F3A RRN3 HIST2H2AC GTF2H4 GTF2H3 HIST2H2BE HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2BB HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH TCEB2 TCEB3 [NAME] TAF1 TAF4 TAF5 WHSC2 GTF2A1 NFX1 CDK7 CPSF3 CPSF2 CPSF1 U2AF2 RBM8A SFRS9 H2AFZ H2AFX ELL GTF3A RNGTT SNAPC2 SNAPC4 SNAPC3 POLR1A POLR1B POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] POLR3A POLR3D PAPOLA TFB2M CSTF3 CSTF2 RNPS1 CSTF1 NFIC | * | hsa-miR-132 (5.5e-40) hsa-miR-496 (3.8e-29) hsa-miR-148a (1.2e-15) hsa-miR-152 (4.1e-14) hsa-miR-802 (7.7e-10) hsa-miR-133a (5.3e-06) hsa-miR-125b (9.8e-06) hsa-miR-1 (6.2e-05) hsa-miR-34a (8.4e-05) hsa-miR-30c (0.00029) hsa-let-7f (0.00064) hsa-miR-328 (0.00093) hsa-miR-204 (0.0017) hsa-miR-153 (0.003) hsa-miR-125a (0.0085) hsa-miR-372 (0.009)
REACTOME_DOWN_STREAM_SIGNAL_TRANSDUCTION | HRAS MAPK1 NRAS KRAS [NAME] [NAME] PIK3R2 MAP2K2 STAT1 STAT3 SRC |  | hsa-miR-132 (4.2e-05) hsa-miR-152 (0.0017) hsa-miR-217 (0.0057)
REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE | [NAME] SNAP25 VAMP2 STXBP1 CHRM3 ITPR1 ITPR2 PLCB1 PRKCA |  | hsa-miR-130a (1.4e-18) hsa-miR-25 (1e-14) hsa-miR-218 (1.2e-10) hsa-miR-92 (1.6e-10) hsa-miR-19a (2.8e-05) hsa-miR-19b (3.9e-05) hsa-miR-183 (7.1e-05) hsa-miR-15b (0.00088) hsa-miR-153 (0.0013) hsa-miR-301 (0.0018)
REACTOME_ORC1_REMOVAL_FROM_CHROMATIN | CCNA2 ORC1L CDC6 ORC6L CDK2 ORC5L ORC2L CDT1 PSMD14 PSMD13 PSMD12 PSMD11 PSMA6 PSMA5 PSMA4 PSMA3 FZR1 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 MCM8 PSMD1 PSMD2 PSMD3 PSMD4 PSMD8 MCM2 MCM3 MCM4 [NAME] [NAME] PSMB10 | * | hsa-miR-802 (1.5e-41) hsa-miR-555 (1.3e-13) hsa-miR-30b (8.1e-13) hsa-miR-146b (1.4e-12) hsa-miR-186 (4.2e-10) hsa-miR-185 (1.2e-06) hsa-miR-146a (1e-05) hsa-miR-620 (4.4e-05) hsa-miR-515-5p (4.7e-05) hsa-miR-643 (0.00061) hsa-miR-767-3p (0.00066) hsa-miR-132 (0.00079) hsa-miR-302c (0.0037) hsa-miR-765 (0.0098) hsa-miR-302b (0.0099)
REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | RAE1 TAF10 TAF13 TAF12 SSRP1 NCBP2 [NAME] SEH1L CTDP1 TH1L NUP188 RANBP1 TPR ERCC2 NUP155 RANGAP1 RDBP GTF2H4 GTF2H3 NUP205 NUP214 NUP210 TCEB2 TCEB3 [NAME] GTF2E1 TAF1 TAF4 TAF5 WHSC2 GTF2A1 NUP85 [NAME] NUP62 RNGTT POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] | * | hsa-miR-496 (4.1e-16) hsa-miR-185 (1.2e-14) hsa-let-7f (9.3e-09) hsa-let-7g (1.3e-08) hsa-miR-148a (7.7e-08) hsa-miR-132 (3.5e-05) hsa-miR-200a (8.7e-05) hsa-miR-152 (9.8e-05) hsa-miR-30d (0.00013) hsa-miR-125b (0.0002) hsa-miR-299-3p (0.00022) hsa-let-7b (0.00055) hsa-miR-320 (0.00059) hsa-miR-133a (0.00081) hsa-miR-128a (0.0015) hsa-miR-93 (0.0026) hsa-miR-30e-5p (0.0033) hsa-miR-206 (0.0034) hsa-miR-204 (0.0037) hsa-miR-302a (0.0043) hsa-miR-302b (0.0049) hsa-miR-186 (0.0063) hsa-miR-372 (0.0066) hsa-miR-30b (0.0095)
REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | BCL2L1 TFDP1 CASP3 BAD BID YWHAB PMAIP1 BMF DIABLO BAK1 BBC3 AKT1 |  | hsa-miR-30b (3.5e-08) hsa-miR-148a (1.3e-07) hsa-miR-148b (1.2e-06) hsa-miR-125b (0.0002)
REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_FREE_FATTY_ACIDS | [NAME] SNAP25 VAMP2 STXBP1 ITPR1 ITPR2 PLCB1 |  | hsa-miR-130a (1.8e-11) hsa-miR-15b (1e-09) hsa-miR-218 (2.2e-07) hsa-miR-19b (9.6e-06) hsa-miR-92 (0.00012) hsa-miR-19a (0.00021) hsa-miR-367 (0.00089) hsa-miR-301 (0.0019) hsa-miR-424 (0.0032) hsa-miR-103 (0.0044) hsa-miR-25 (0.0061) hsa-miR-32 (0.0079)
REACTOME_G1_PHASE | [NAME] E2F5 CCND1 CDK7 |  | hsa-miR-1 (0.00031) hsa-miR-496 (0.0071)
REACTOME_FRS2MEDIATED_CASCADE | FGF7 FGF9 FGF1 FGF2 KL FGF10 FGFR2 FGFR1 |  | hsa-miR-218 (1.3e-12) hsa-miR-183 (4.1e-06) hsa-miR-543 (0.00024) hsa-miR-214 (0.0029) hsa-miR-103 (0.003)
REACTOME_SNRNP_ASSEMBLY | RAE1 NCBP2 NCBP1 SNRPD3 SNRPD1 SEH1L NUP188 TPR GEMIN6 GEMIN7 GEMIN5 NUP155 WDR77 NUP205 NUP214 NUP210 NUP85 NUP98 NUP93 CLNS1A NUP50 NUP62 NUPL1 SNRPB SNRPF SNRPE SNRPG | * | hsa-miR-125a (5.8e-21) hsa-miR-129-3p (3.7e-16) hsa-miR-185 (1.1e-10) hsa-miR-514 (2.3e-09) hsa-miR-205 (3.3e-07) hsa-miR-125b (0.003) hsa-miR-568 (0.0084)
REACTOME_DUAL_INCISION_REACTION_IN_TC_NER | XAB2 ERCC3 ERCC4 ERCC1 ERCC2 GTF2H4 GTF2H3 CDK7 POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] |  | hsa-miR-496 (8.6e-06)
REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION | ORC1L CCNB1 ORC6L ORC5L ORC2L CDC25A MCM8 | * | hsa-miR-185 (1.2e-13) hsa-miR-30b (1.1e-11) hsa-let-7f (0.0015) hsa-miR-30c (0.0041) hsa-let-7b (0.0064)
REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | GNAI1 GNAZ ADCY3 ADCY4 ADCY8 ADCY5 ADCY6 |  | hsa-miR-19b (3.6e-08) hsa-miR-335 (1.3e-07) hsa-miR-19a (0.00017) hsa-miR-485-3p (0.00039) hsa-miR-25 (0.00061) hsa-miR-218 (0.0014) hsa-miR-92b (0.0016)
REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | SNAP25 VAMP2 STXBP1 |  | hsa-miR-150 (0.0083)
REACTOME_LAGGING_STRAND_SYNTHESIS | [NAME] FEN1 RPA3 PCNA POLA1 POLA2 POLD4 POLD1 POLD2 PRIM2 RFC5 RFC3 RFC4 RFC2 | * | hsa-miR-154 (7.1e-15) hsa-miR-1 (1.2e-10) hsa-miR-610 (4.7e-05) hsa-miR-134 (8.4e-05) hsa-miR-515-5p (0.0083)
REACTOME_RNA_POLYMERASE_I_PROMOTER_CLEARANCE | HIST1H4K HIST1H4A HIST1H4B HIST1H4E HIST1H4F HIST1H4I HIST1H4J HIST1H4H HIST1H3J HIST1H3A [NAME] HIST1H3G HIST1H3H HIST1H3I H2BFS HIST3H2BB UBTF HIST2H2AA3 HIST1H2BO HIST1H2BM HIST1H2BN HIST1H2BK HIST1H2BL HIST1H2BI HIST1H2BJ H3F3A HIST2H2AC GTF2H3 HIST2H2BE HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2BB HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2AK CDK7 H2AFZ H2AFX POLR1B POLR2H POLR2K | * | hsa-miR-496 (1.6e-107) hsa-miR-802 (9.3e-28) hsa-miR-24 (1.7e-11) hsa-miR-328 (1.2e-05) hsa-miR-584 (9.2e-05) hsa-miR-132 (0.00011) hsa-miR-659 (0.0013) hsa-miR-155 (0.0017)
REACTOME_HEMOSTASIS | A2M GNG2 GNG7 F8 SERPING1 SIRPA F3 TFPI GNAI1 [NAME] [NAME] SELP IGF1 P2RY12 TEK ADRA2A ADRA2C P2RX1 MERTK SLC7A10 JAM2 JAM3 PF4 FIGF ATP1B2 APOB [NAME] VEGFC CD36 PLAT PLA2G4A TF ITPR1 ITPR2 [NAME] PDGFA MMRN1 TTN CAV1 CLU ITGB1 ALB PLCG2 RAP1A MGLL PRKCA PROS1 RASGRP2 SCG3 PIK3R1 |  | hsa-miR-92 (1.1e-13) hsa-miR-149 (1.6e-05) hsa-miR-19b (1.6e-05) hsa-miR-32 (3.7e-05) hsa-miR-218 (5.6e-05) hsa-miR-424 (0.00012) hsa-miR-485-3p (0.00023) hsa-miR-142-5p (0.00025) hsa-miR-367 (0.0005) hsa-miR-20b (0.003) hsa-miR-144 (0.0047) hsa-miR-770-5p (0.0072)
REACTOME_INTEGRIN_ALPHAIIBBETA3_SIGNALING | APBB1IP SOS1 FGA RAPGEF3 RAP1A RAP1B TLN1 RASGRP2 VWF |  | hsa-miR-19b (3.9e-06) hsa-miR-92 (0.00016) hsa-miR-149 (0.00032) hsa-miR-181c (0.0012) hsa-miR-19a (0.0013) hsa-miR-367 (0.0015) hsa-miR-144 (0.0019)
REACTOME_RNA_POLYMERASE_I_PROMOTER_OPENING | HIST1H4K HIST1H4A HIST1H4B HIST1H4E HIST1H4F HIST1H4I HIST1H4J HIST1H4H HIST1H3J HIST1H3A [NAME] HIST1H3G HIST1H3H HIST1H3I H2BFS HIST3H2BB UBTF HIST2H2AA3 HIST1H2BO HIST1H2BM HIST1H2BN HIST1H2BK HIST1H2BL HIST1H2BI HIST1H2BJ H3F3A HIST2H2AC HIST2H2BE HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2BB HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2AK [NAME] | * | hsa-miR-24 (1.3e-38) hsa-miR-802 (6.7e-36) hsa-miR-9 (8.9e-09) hsa-miR-544 (1.7e-05) hsa-miR-155 (0.00011) hsa-miR-659 (0.00047) hsa-miR-212 (0.00053) hsa-miR-328 (0.0043) hsa-miR-584 (0.0085)
REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | [NAME] PSMD11 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] | * | hsa-miR-186 (4.4e-28) hsa-miR-802 (1e-22) hsa-miR-146b (1.5e-10) hsa-miR-146a (4.2e-09) hsa-miR-132 (0.00023) hsa-miR-515-5p (0.00026) hsa-miR-30b (0.00057) hsa-miR-765 (0.00072) hsa-miR-555 (0.0023)
REACTOME_SOS_MEDIATED_SIGNALLING | HRAS MAPK1 NRAS KRAS [NAME] MAP2K2 |  | [NAME] (0.00059) hsa-miR-148b (0.0054)
REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | GPR44 PTGER2 PTGER3 PTGER4 GPR17 PTGDR PTGFR |  | hsa-miR-23b (5.2e-14) hsa-miR-25 (1.8e-10) hsa-miR-92 (1.7e-09) hsa-miR-145 (3.8e-09) hsa-miR-367 (2.4e-08) hsa-miR-32 (0.0027)
REACTOME_TRANSCRIPTION_COUPLED_NER | [NAME] ERCC4 ERCC1 ERCC2 PCNA GTF2H4 GTF2H3 POLE2 POLD4 POLD1 POLD2 CDK7 POLE RFC5 RFC3 RFC4 RFC2 POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] | * | hsa-miR-154 (5.6e-12) hsa-miR-496 (6.5e-07) hsa-miR-217 (9.3e-06)
REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | RAD1 DBF4 HUS1 CLSPN ATRIP [NAME] CDC7 CDC6 ORC6L CDK2 ORC5L ORC2L CDC25C CDC25A RFC5 RFC3 RFC4 RFC2 CHEK1 MCM10 MCM8 MCM2 MCM3 MCM4 [NAME] | * | hsa-miR-30c (1.5e-12) hsa-miR-128b (2.6e-07) hsa-miR-30b (2.8e-07) hsa-miR-185 (8.7e-07) hsa-let-7f (2.7e-05) hsa-miR-34a (0.00019) hsa-miR-302a (0.0026) hsa-let-7b (0.0041) hsa-let-7e (0.0049) hsa-miR-643 (0.0065) hsa-miR-302c (0.0095)
REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT | RPL18 [NAME] RPL13 RPL15 RPLP2 RPL10 FAU RPL11 RPL12 HNF4G RPS18 HNF4A [NAME] RPS14 [NAME] RPS11 RPS25 [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 [NAME] RPL41 RPL35 RPL37 RPL38 RPL30 RPL32 [NAME] RPL26 RPL27 RPL24 RPL29 RPL23 RPL22 [NAME] SLC2A2 RPS27A RPL35A RPL6 RPL9 RPL3 RPL5 RPL10A RPL7A RPL4 RPL37A PAX6 PAX4 RPS3 RPS3A RPS4X PKLR RPS15A RPL13A RBPJ RPL27A FGF10 [NAME] | * | hsa-miR-142-5p (1e-61) hsa-miR-376a (4e-39) hsa-miR-181c (1.3e-38) hsa-miR-376b (9.6e-35) hsa-miR-218 (4.5e-29) hsa-miR-23b (8.6e-25) hsa-miR-144 (4.9e-19) hsa-miR-137 (8e-14) hsa-miR-101 (1.4e-10) hsa-miR-21 (3.8e-10) hsa-miR-150 (2.4e-07) hsa-miR-20a (7.5e-06) hsa-miR-365 (4.2e-05) hsa-miR-181a (0.0001) hsa-miR-557 (0.0002) hsa-miR-15b (0.00084) hsa-miR-181b (0.0076) hsa-miR-375 (0.0092)
REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | FABP4 PPP1CC CAV1 MGLL LIPE |  | hsa-miR-218 (8.3e-18) hsa-miR-142-5p (4.7e-09) hsa-miR-32 (7.1e-07) hsa-miR-106b (1.1e-06) hsa-miR-92 (2.2e-05) hsa-miR-137 (0.0018) hsa-miR-20a (0.0023)
REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | EDC4 EDC3 DDX6 LSM5 LSM4 LSM2 LSM1 XRN1 DCP2 |  | hsa-miR-30b (0.0053) hsa-miR-9 (0.0091)
REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX | ORC1L CDC6 ORC6L ORC5L ORC2L CDT1 PSMD14 PSMD13 PSMD11 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC2 MCM8 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] | * | hsa-miR-186 (1.1e-16) hsa-miR-802 (1.7e-16) hsa-miR-185 (6.6e-09) hsa-miR-146b (8.7e-08) hsa-miR-620 (8.8e-08) hsa-miR-146a (0.00022) hsa-miR-643 (0.00041) hsa-miR-767-3p (0.00044) hsa-miR-555 (0.0032)
REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | MEF2C MEF2A PPP2CB RPS6KA5 RPS6KA3 DUSP6 ATF1 PPP2R1B |  | hsa-miR-145 (2.7e-17) hsa-miR-142-5p (1.2e-08) hsa-miR-183 (6.6e-08) hsa-miR-20a (9.5e-06) hsa-miR-23b (0.00016) hsa-miR-130b (0.0002) hsa-miR-19b (0.00063)
REACTOME_FORMATION_AND_MATURATION_OF_MRNA_TRANSCRIPT | CCAR1 PTBP1 DHX9 TAF10 TAF13 TAF12 SF3B4 SF3B2 SSRP1 TXNL4A NCBP2 NCBP1 SNRPD3 SNRPD1 PRPF4 PRPF6 FUS SUPT16H CTDP1 TH1L ERCC2 [NAME] GTF2H4 GTF2H3 TCEB2 TCEB3 TCEB1 RNMT GTF2E1 DDX23 [NAME] TAF4 TAF5 WHSC2 GTF2A1 NFX1 CDK7 CPSF3 CPSF2 CPSF1 U2AF2 RBM8A SFRS9 ELL RNGTT POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] CD2BP2 PAPOLA EFTUD2 SNRPB SNRPF SNRPE SNRPG CSTF3 CSTF2 RNPS1 SMC1A CSTF1 | * | hsa-miR-496 (6.8e-15) hsa-miR-148a (3.9e-10) hsa-miR-30b (7.3e-07) hsa-miR-152 (2.2e-06) hsa-miR-132 (2.2e-06) hsa-miR-212 (3.9e-05) hsa-miR-9 (7.7e-05) hsa-miR-194 (0.00023) hsa-miR-331 (0.00088) hsa-miR-24 (0.0016) hsa-miR-133a (0.0028) hsa-miR-148b (0.005) hsa-miR-125b (0.0052) hsa-miR-204 (0.0056) hsa-let-7b (0.0068) hsa-miR-302a (0.0077) hsa-miR-299-3p (0.0079)
REACTOME_ENDOGENOUS_STEROLS | CYP7A1 CYP1B1 CYP46A1 CYP7B1 CYP17A1 CYP8B1 CYP39A1 CYP19A1 CYP11B1 CYP11A1 |  | hsa-miR-27b (1.7e-07) hsa-miR-758 (0.00091)
REACTOME_LIPOPROTEIN_METABOLISM | A2M APOA4 ABCA1 APOB LCAT HSPG2 ALB LPL LIPC |  | hsa-miR-145 (9e-13) hsa-miR-142-5p (9.6e-09) hsa-miR-101 (6.7e-08) hsa-miR-183 (3.8e-07) hsa-miR-19b (0.00022) hsa-miR-149 (0.00022) hsa-miR-33 (0.0019) hsa-miR-19a (0.0047) hsa-miR-15b (0.0049) hsa-miR-181b (0.0057) hsa-miR-29b (0.0079)
REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY | RORB RXRG HNF4A ESRRA NR5A2 NR2E1 NR2C1 NR4A2 NR4A1 NR4A3 ESR2 NR3C2 NR3C1 RARB NR1H4 NR1H3 NRBF2 PPARA PPARG NR2F1 NR1D2 THRA THRB NR0B1 |  | hsa-miR-335 (3.4e-31) hsa-miR-181b (1.4e-16) hsa-miR-33 (2.1e-12) hsa-miR-181c (5.9e-07) hsa-miR-149 (6.2e-07) hsa-miR-367 (1.7e-06) hsa-miR-137 (3.6e-05) hsa-miR-323 (4.6e-05) hsa-miR-130b (6.3e-05) hsa-miR-183 (0.00011) hsa-miR-375 (0.00024) hsa-miR-144 (0.0014) hsa-miR-25 (0.0017) hsa-miR-103 (0.0026) hsa-miR-21 (0.0051) hsa-miR-19b (0.0064)
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS | [NAME] PTH2R GNAZ PDE11A GIP GNG13 GNG11 PDE1A PDE2A GNG10 PDE3B PDE4C ADORA2B DRD5 PDE7B PDE8B PDE8A PTGER2 PTGER4 ADRB2 VIP ADCY3 ADCY4 ADCY8 ADCY6 [NAME] ADM PTGDR AVPR2 SCTR PTHLH INSL3 TAAR9 RAMP2 CALCR CRH |  | hsa-miR-335 (7.8e-18) hsa-miR-92 (5e-15) hsa-miR-181c (6e-08) hsa-miR-101 (5.7e-07) hsa-miR-485-3p (6.3e-05) hsa-miR-23b (0.00021) hsa-miR-23a (0.00033) hsa-miR-19a (0.00067) hsa-miR-19b (0.0011) hsa-miR-424 (0.0016) hsa-miR-32 (0.0024) hsa-miR-181b (0.0039) hsa-miR-181a (0.0085)
REACTOME_DARPP32_EVENTS | PPP1R1B [NAME] PPP3CA PRKAR2B PDE4C PRKAR1A PPP2R1B [NAME] |  | hsa-miR-183 (5e-05)
REACTOME_NEUROTRANSMITTER_RELEASE_CYCLE | [NAME] SNAP25 VAMP2 SLC1A7 DDC STXBP1 GLS SYN2 SLC17A7 |  | hsa-miR-181c (1.5e-12) hsa-miR-25 (8.6e-12) hsa-miR-23b (1.5e-11) hsa-miR-335 (1.8e-09) hsa-miR-367 (9.6e-09) hsa-miR-181a (3.5e-08) hsa-miR-92 (4.3e-08) hsa-miR-218 (1.2e-05) hsa-miR-106b (0.00066) hsa-miR-15b (0.0039) hsa-miR-20a (0.004)
REACTOME_P75NTR_SIGNALS_VIA_NFKB | RELA IKBKB MYD88 IRAK1 PRKCI SQSTM1 RIPK2 |  | hsa-miR-142-3p (0.00016)
REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | A2M ABCA1 LCAT ALB |  | hsa-miR-142-5p (2.4e-23) hsa-miR-183 (2.5e-12) hsa-miR-19b (8.6e-12) hsa-miR-19a (3.3e-10) hsa-miR-145 (1.2e-07) hsa-miR-101 (0.0047) hsa-miR-181b (0.0074)
REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | PACS1 AP1S3 AP1S1 AP1G1 AP1M1 AP1M2 AP1B1 |  | hsa-miR-148b (1.8e-05) hsa-let-7a (0.0017) hsa-miR-299-3p (0.003)
REACTOME_ERKS_ARE_INACTIVATED | PPP2CB DUSP6 PPP2R1B |  | hsa-miR-145 (1.1e-13) hsa-miR-92 (6.8e-05) hsa-miR-32 (0.00012) hsa-miR-183 (0.0052)
REACTOME_METABOLISM_OF_AMINO_ACIDS | PCBD1 HSD17B10 ASL ALDH18A1 AZIN1 SLC1A4 SLC43A2 SLC7A11 [NAME] BCKDHA PYCR1 KMO AGMAT SLC25A15 SLC7A5 SLC7A7 OAZ3 ASNS SLC36A1 GOT2 GOT1 GCDH CKMT1A SLC16A10 SLC25A2 BCAT2 PSMD14 PSMD13 PSMD12 PSMD11 PSMA6 PSMA5 PSMA4 PSMA3 SLC38A5 SRM PSMA7 PSMB4 IVD PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 TDO2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] PSMB10 SLC6A6 |  | hsa-miR-802 (0.00064) hsa-miR-320 (0.0047)
REACTOME_GLUCURONIDATION | UGT2B28 UGT2B11 UGT2B10 UGT2B15 UGP2 UGT1A8 UGT2A1 UGT2B4 UGT2B7 |  | hsa-miR-92 (8.6e-23) hsa-miR-367 (3.8e-16) hsa-miR-25 (1.5e-11) hsa-miR-92b (3.1e-09) hsa-miR-32 (1.5e-05) hsa-miR-137 (0.00038)
REACTOME_LYSOSOME_VESICLE_BIOGENESIS | ARF1 [NAME] CLTC AP1S3 AP1S1 DNM2 AP1G1 M6PR [NAME] AP1M2 AP1B1 CTSZ | * | [NAME] (1.1e-11) hsa-miR-148b (1.4e-07) hsa-miR-299-3p (2.7e-06) hsa-miR-125b (3e-06) hsa-miR-1 (1e-05) hsa-miR-152 (0.00012) hsa-miR-125a (0.00012) hsa-miR-205 (0.00056) hsa-miR-204 (0.00093) hsa-let-7e (0.0011) hsa-let-7f (0.0017) hsa-let-7a (0.0071)
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS | AGTR1 [NAME] GNG13 GNG11 CCL23 DGKI HTR2A NTSR2 ADRA1B CHRM3 CCK TAC1 OXTR ANXA1 EDN3 EDN1 GRK5 EDNRB PROK2 PROK1 NMB PTGFR ITPR1 ITPR2 KALRN TACR2 MGLL PLCB1 NPFF PIK3R1 NTS |  | hsa-miR-145 (3.4e-12) hsa-miR-142-5p (5.7e-12) hsa-miR-19a (4.2e-07) hsa-miR-92 (8e-07) hsa-miR-130a (1.9e-06) hsa-miR-367 (0.0001) hsa-miR-218 (0.00015) hsa-miR-25 (0.00021) hsa-miR-301 (0.00044) hsa-miR-19b (0.0035)
REACTOME_PKA_ACTIVATION | PRKAR2B PRKAR1A ADCY3 ADCY4 ADCY8 ADCY5 ADCY6 |  | hsa-miR-92 (4.6e-09) hsa-miR-335 (7.6e-09) hsa-miR-19b (5.5e-05) hsa-miR-367 (0.0012)
[NAME] | RPL18 [NAME] RPL13 RPL15 RPLP2 RPL10 FAU RPL11 [NAME] RPS14 [NAME] [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 RPL41 RPL37 RPL32 [NAME] RPL26 RPL27 RPL24 RPL29 RPL22 [NAME] RPL35A RPL6 RPL9 RPL3 RPL5 RPL10A RPL7A RPL4 RPL37A RPS3 RPS3A RPS4X RPS15A RPL13A RPL27A POLR2A | * | hsa-miR-142-5p (1e-77) hsa-miR-376a (6.1e-27) hsa-miR-218 (5.8e-25) hsa-miR-137 (1.2e-15) hsa-miR-376b (1.5e-11) hsa-miR-21 (2.8e-10) hsa-miR-153 (2.7e-05)
REACTOME_GENE_EXPRESSION | [NAME] MED20 RAE1 MED26 CCAR1 PTBP1 MED12 MED14 MED13 SARS2 [NAME] GARS TAF10 TAF13 AARS2 SF3B4 SF3B2 PARS2 TXNL4A NCBP2 NCBP1 SNRPD3 SNRPD1 NR2C2 PRPF6 TARS2 IARS2 RPL26L1 HARS FUS NR1I3 PPARD SEH1L FARSB FARSA CTDP1 CARS TH1L EIF3I NUP188 TPR TARS NUP155 LSM2 YARS RDBP RPS26 GTF2H3 DARS2 NUP205 NUP214 NUP210 MARS TCEB2 TCEB3 [NAME] SNRPA1 HNRNPU EARS2 TAF1 TAF4 TAF5 CARS2 GTF2A1 NARS2 NUP85 [NAME] NUP98 NUP93 VARS U2AF2 SFRS9 EIF2B5 ELL NUP50 [NAME] NR2F6 MED1 POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] CD2BP2 PAPOLA NRBP1 EFTUD2 NUPL1 SNRPB SNRPF SNRPE SNRPG CSTF3 CSTF2 RNPS1 CSTF1 EIF4G1 LARS |  | hsa-miR-152 (8.1e-05) hsa-miR-186 (0.00087) hsa-miR-320 (0.0045) hsa-miR-496 (0.0052)
REACTOME_SMOOTH_MUSCLE_CONTRACTION | ACTG2 ACTA2 SORBS3 SORBS1 PXN [NAME] MYLK CALD1 TPM2 TPM1 |  | hsa-miR-145 (1.8e-38) hsa-miR-142-5p (3.7e-28) hsa-miR-770-5p (5.9e-19) hsa-miR-218 (2.1e-18) hsa-miR-20a (5.4e-14) hsa-miR-106b (1.7e-09) hsa-miR-137 (5e-06) hsa-miR-16 (5.7e-06) hsa-miR-199b (9.1e-06) hsa-miR-365 (5.5e-05) hsa-miR-29b (0.00062) hsa-miR-96 (0.0031)
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS | AGTR1 AGTR2 GPER SSTR1 NPY5R PENK [NAME] CCL23 CCL21 CCBP2 NPY1R CCL16 CXCL12 GALR1 NTSR2 CCL2 CX3CL1 CCRL1 CCK TAC1 OXTR PF4 ANXA1 EDN3 EDN1 PPBP CX3CR1 PRLHR POMC NPY EDNRB PROK2 PROK1 CXCL1 AVPR2 CXCL3 CXCL2 NMB DARC [NAME] |  | hsa-miR-144 (5e-34) hsa-miR-23b (5.3e-19) hsa-miR-218 (1.5e-16) hsa-miR-142-5p (2.5e-14) hsa-miR-15a (3e-12) hsa-miR-101 (1e-09) hsa-miR-23a (1.9e-09) hsa-miR-15b (5.2e-08) hsa-miR-214 (1.6e-05) hsa-miR-29b (9.1e-05) hsa-miR-29a (0.00024) hsa-miR-33 (0.00076) hsa-miR-323 (0.0017)
REACTOME_CELL_CELL_ADHESION_SYSTEMS | CTNNB1 PVRL3 CDH12 CDH13 CDH10 CLDN8 CLDN5 CLDN2 CDH3 CDH4 CDH6 CDH9 PARD3 CLDN19 CLDN10 CLDN11 CLDN23 PARD6G |  | hsa-miR-32 (2.3e-09) hsa-miR-15a (4.5e-06) hsa-miR-92 (5.7e-06) hsa-miR-25 (5.7e-06) hsa-miR-181c (1.4e-05) hsa-miR-181b (0.0025) hsa-miR-16 (0.0027) hsa-miR-183 (0.0085)
REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE | AZIN1 OAZ3 OAZ1 PSMD14 PSMD13 PSMD12 PSMD11 PSMA1 PSMA6 PSMA5 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] PSMB10 | * | hsa-miR-802 (1.4e-26) hsa-miR-186 (8e-14) hsa-miR-146a (1.6e-11) hsa-miR-515-5p (3.4e-08) hsa-miR-146b (9.8e-06) hsa-miR-30b (2.4e-05) hsa-miR-620 (0.00025) hsa-miR-603 (0.00028) hsa-miR-765 (0.00037) hsa-miR-555 (0.0012) hsa-miR-212 (0.0019) hsa-miR-132 (0.0045)
[NAME] | TSGA14 [NAME] [NAME] TUBG1 TUBG2 NDE1 TUBA4A NEK2 ALMS1 CEP250 CETN2 YWHAG CEP72 CEP78 PKMYT1 CEP70 FGFR1OP TUBGCP2 TUBB2C CCNA2 PCNT NUMA1 CCNB1 CCNB2 XPO1 AZI1 TUBB PLK4 PLK1 CDK7 ODF2 CDC25C CDC25A [NAME] | * | hsa-miR-148b (2.5e-15) hsa-miR-30b (4.7e-13) hsa-miR-148a (8.3e-08) hsa-let-7a (3.8e-07) hsa-miR-185 (5e-07) hsa-miR-34a (7.8e-07) hsa-miR-496 (2.9e-06) hsa-miR-155 (2.8e-05) hsa-miR-30c (5.6e-05) hsa-miR-125b (0.00017) hsa-miR-320 (0.0014) hsa-miR-186 (0.0017) hsa-let-7f (0.0019) hsa-miR-346 (0.0039)
REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | PPP2R5D CACNB3 NDUFB11 NDUFB10 PDK3 SDHC CYC1 UQCRQ GCK MDH2 ALDOA [NAME] STX1A PRKAA2 COX5A PRKAB1 COX6C COX8A UQCRC1 PFKL GAPDH GNG5 NDUFA13 NDUFA11 GNB2 GNB1 GNB3 PRKAR2A SLC2A1 STK11 ATP5J2 PRKAR1B [NAME] CACNA1D NDUFS6 NDUFS8 NDUFS2 ATP5G1 ADCY1 ADCY7 PFKFB4 PFKFB2 COX6B1 COX6A1 ADCY9 PGK1 CPT2 NDUFC2 NDUFB4 NDUFB9 NDUFB2 NDUFA3 NDUFA7 |  | hsa-let-7f (0.0037)
REACTOME_GTP_HYDROLYSIS_AND_JOINING_OF_THE_60S_RIBOSOMAL_SUBUNIT | RPL18 [NAME] RPL13 RPL15 RPLP2 RPL10 FAU RPL11 [NAME] RPS14 [NAME] [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 RPL41 EIF4A2 RPL37 RPL32 [NAME] RPL26 RPL27 RPL24 RPL29 RPL22 RPL21 EIF5 RPS27A RPL35A RPL6 RPL9 RPL3 RPL5 RPL10A RPL7A RPL4 RPL37A RPS3 RPS3A RPS4X RPS15A RPL13A RPL27A EIF3D EIF3G EIF3E EIF3F [NAME] | * | hsa-miR-376a (1.1e-48) hsa-miR-19b (2.9e-38) hsa-miR-376b (1.1e-29) hsa-miR-183 (1.4e-21) hsa-miR-149 (4e-21) hsa-miR-142-5p (1.7e-15) hsa-miR-15a (4e-15) hsa-miR-101 (1.5e-11) hsa-miR-335 (5.4e-11) hsa-miR-19a (2.9e-08) hsa-miR-181c (3.3e-08) hsa-miR-145 (1.3e-07) hsa-miR-543 (4.3e-07) hsa-miR-16 (3.2e-06) hsa-miR-135a (6.3e-06) hsa-miR-26a (9.4e-06) hsa-miR-181a (1.1e-05) hsa-miR-218 (2.6e-05) hsa-miR-135b (0.00033) hsa-miR-137 (0.0015) hsa-miR-15b (0.0026) hsa-miR-181b (0.0037)
REACTOME_POLYMERASE_SWITCHING | PCNA POLA1 POLA2 POLD4 POLD1 POLD2 PRIM2 RFC5 RFC3 RFC4 RFC2 |  | hsa-miR-154 (6.2e-16) hsa-miR-1 (1.2e-07) hsa-miR-217 (0.0043) hsa-miR-134 (0.0072)
REACTOME_ZINC_TRANSPORTATION | SLC39A10 SLC39A7 SLC39A3 SLC39A1 SLC30A1 SLC30A6 SLC30A7 |  | hsa-miR-217 (5.8e-05)
REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION | [NAME] FBXO5 TYMS ORC1L PCNA CCNE1 CDC6 RRM2 POLA1 POLA2 CCNB1 ORC6L ORC5L ORC2L CDC25A PRIM2 CDT1 MCM8 | * | hsa-miR-30b (5.3e-28) hsa-let-7b (3.1e-07) hsa-miR-186 (5.7e-06) hsa-miR-643 (4.2e-05) hsa-miR-200a (0.00016) hsa-let-7i (0.00019) hsa-miR-148a (0.00028) hsa-miR-148b (0.00034) hsa-miR-185 (0.00041) hsa-miR-141 (0.00083) hsa-miR-125b (0.002) hsa-miR-152 (0.0021) hsa-miR-210 (0.0052) hsa-miR-9 (0.0082)
REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION | APBB1IP SOS1 FGA ADRA2A ADRA2C ADRA2B [NAME] RAP1A RAP1B TLN1 RASGRP2 VWF |  | hsa-miR-181c (1.1e-08) hsa-miR-149 (7e-08) hsa-miR-19b (3.1e-07) hsa-miR-19a (6.3e-05) hsa-miR-96 (0.0013) hsa-miR-144 (0.0026) hsa-miR-32 (0.0064) hsa-miR-181a (0.0097)
REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | GRIN2B [NAME] GRIN2A [NAME] CREB1 CALM3 [NAME] CAMK2B NEFL CAMK2A |  | hsa-miR-181c (3.3e-08) hsa-miR-23b (0.00011) hsa-miR-367 (0.00073) hsa-miR-130b (0.0023) hsa-miR-25 (0.0085)
REACTOME_ACTIVATION_OF_RAC | NCK1 SOS1 SOS2 SLIT2 PAK7 PAK3 |  | hsa-miR-149 (3e-07) hsa-miR-15a (0.0043)
REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_COMPLEX | PDHA1 PDK2 PDK4 DLD |  | hsa-miR-15a (0.00026) hsa-miR-181c (0.0028) hsa-miR-181a (0.0095)
REACTOME_FRS2_MEDIATED_ACTIVATION | HRAS BRAF MAPK1 NRAS FRS2 [NAME] |  | hsa-miR-217 (4.2e-07) hsa-miR-30c (0.00053) hsa-miR-148b (0.0012) hsa-miR-148a (0.0041) hsa-miR-152 (0.006) hsa-let-7f (0.0067)
REACTOME_SIGNALLING_BY_NGF | HRAS PPP2R5D BRAF MAPK1 AP2S1 ARHGEF18 ARHGEF16 ARHGEF11 THEM4 NRAS GSK3A GSK3B RALA FRS2 RELA ADORA2A MAPKAPK3 MAPKAPK2 FGD3 ARHGDIA AP2M1 FURIN HDAC1 IKBKB PREX1 CASP3 CASP2 BAD MYD88 PSENEN CAMK4 KRAS AP2B1 PDPK1 YWHAB AP2A2 GRB2 DNAL4 CLTC SHC1 IRAK1 PRKCI PRKCD MDM2 TRIB3 PIK3R2 MAGED1 MAP2K2 ARHGEF2 ARHGEF1 PCSK6 RPS6KA1 [NAME] AKT1S1 VAV3 VAV2 PRKAR1B TSC2 APH1A SMPD2 ADCY1 ADCY7 ADRBK1 TRIO PSEN1 PSEN2 AATF ITPR3 STAT3 MAPK12 ADCY9 MAPK13 RIPK2 ELK1 SRC AKT1 ECT2 |  | hsa-miR-138 (2.5e-09) hsa-let-7f (0.00012) hsa-miR-132 (0.00012) hsa-miR-148a (0.0072)
REACTOME_MUSCLE_CONTRACTION | ACTG2 MYH3 TNNI1 TNNI2 ACTA2 SORBS3 SORBS1 VIM NEB PXN DMD MYBPC2 MYBPC1 [NAME] TTN TNNT3 MYL2 MYL3 MYL1 MYL9 MYLK TLN1 CALD1 TPM2 TPM1 MYL6B | * | hsa-miR-145 (5.6e-26) hsa-miR-199b (6.5e-21) hsa-miR-20a (1.1e-17) hsa-miR-181c (3e-15) hsa-miR-137 (5.7e-11) hsa-miR-101 (1.4e-10) hsa-miR-770-5p (1.1e-08) hsa-miR-142-5p (1.3e-08) hsa-miR-144 (4.2e-08) hsa-miR-218 (2.3e-05) hsa-miR-214 (0.00071) hsa-miR-365 (0.0012) hsa-miR-208 (0.0022) hsa-miR-153 (0.01)
REACTOME_SEROTONIN_NEUROTRANSMITTER_RELEASE_CYCLE | SNAP25 VAMP2 DDC STXBP1 SYN2 |  | hsa-miR-92 (3.4e-15) hsa-miR-25 (1.2e-13) hsa-miR-335 (1.5e-11) hsa-miR-367 (2.9e-08) hsa-miR-153 (5.6e-06) hsa-miR-130a (0.00022) hsa-miR-15b (0.00088) hsa-miR-218 (0.0019) hsa-miR-429 (0.0079)
REACTOME_DOUBLE_STRAND_BREAK_REPAIR | [NAME] RAD51 BRCA2 PRKDC RPA3 H2AFX [NAME] | * | hsa-miR-24 (9.7e-09)
REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | [NAME] CCNE1 CDK7 CDK2 CDC25A [NAME] PSMD12 PSMD11 PSMA6 PSMA5 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] PSMB10 | * | hsa-miR-496 (1e-18) hsa-miR-30b (9.9e-14) hsa-miR-186 (1.2e-10) hsa-miR-146b (4.2e-09) hsa-miR-765 (6.2e-09) hsa-miR-802 (2.5e-07) hsa-miR-555 (1.7e-06) hsa-miR-146a (0.00033) hsa-miR-138 (0.00046) hsa-miR-302a (0.00047) hsa-miR-515-5p (0.001) hsa-let-7a (0.0011) hsa-miR-30e-5p (0.0034) hsa-miR-302b (0.0073)
REACTOME_SIGNALING_BY_VEGF | FIGF FLT4 VEGFC PDGFC |  | hsa-miR-149 (3.2e-16)
REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE | CYP7A1 CYP1A1 CYP1A2 CYP1B1 CYP2B6 CYP46A1 CYP7B1 CYP17A1 CYP8B1 CYP2C18 CYP2F1 CYP2A13 CYP2A6 CYP2U1 CYP4A11 CYP3A4 CYP3A5 CYP3A7 CYP26A1 CYP4B1 CYP39A1 PTGIS CYP19A1 CYP11B1 CYP11A1 CYP26B1 |  | hsa-miR-20a (2.1e-26) hsa-miR-149 (1.5e-18) hsa-miR-27b (6.1e-11) hsa-miR-106b (3.1e-08) hsa-let-7d (0.0016) hsa-miR-758 (0.002) hsa-miR-15b (0.0044)
REACTOME_SIGNALING_BY_WNT | PPP2R5D GSK3B BTRC PSMD14 PSMD13 PSMD11 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 AXIN1 PSMC4 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] | * | hsa-miR-30b (1.3e-24) hsa-miR-802 (6.3e-09) hsa-miR-146a (4.5e-06) hsa-miR-515-5p (1.4e-05) hsa-miR-186 (1.9e-05) hsa-miR-765 (7.3e-05) hsa-miR-30d (9.4e-05) hsa-miR-555 (0.00083) hsa-miR-30c (0.0067) hsa-miR-146b (0.0081)
REACTOME_GLOBAL_GENOMIC_NER | LIG1 RAD23B DDB1 RPA3 ERCC3 ERCC4 ERCC1 ERCC2 PCNA GTF2H4 GTF2H3 POLE2 POLD4 POLD1 POLD2 CDK7 POLE RFC5 RFC3 RFC4 RFC2 |  | hsa-miR-496 (1.9e-05)
REACTOME_SIGNALLING_TO_ERKS | HRAS BRAF MAPK1 NRAS RALA FRS2 MAPKAPK3 MAPKAPK2 KRAS RIT1 [NAME] MAPK13 SRC |  | hsa-miR-217 (4.4e-28) hsa-miR-30b (1.1e-07) hsa-miR-148a (2.3e-07) hsa-miR-320 (2.4e-07) hsa-miR-152 (4.7e-05) hsa-miR-132 (5e-05) hsa-let-7a (0.002) hsa-miR-148b (0.0066)
REACTOME_CLATHRIN_DERIVED_VESICLE_BUDDING | ARF1 [NAME] RAB5C CLTC TGOLN2 AP1S3 AP1S1 STX4 DNM2 AP1G1 M6PR [NAME] AP1M1 AP1M2 AP1B1 AP3B1 NAPA CTSZ |  | [NAME] (1.1e-19) hsa-miR-185 (4.4e-10) hsa-miR-152 (1.7e-08) hsa-miR-125b (2e-06) hsa-miR-138 (0.00021) hsa-miR-299-3p (0.00078) hsa-miR-320 (0.0015) hsa-miR-194 (0.0044)
REACTOME_TRNA_AMINOACYLATION | SARS2 WARS2 GARS AARS2 PARS2 MARS2 TARS2 IARS2 HARS FARSB FARSA CARS TARS LARS2 YARS DARS2 MARS EARS2 CARS2 NARS2 VARS EPRS NARS LARS | * | hsa-miR-205 (2.9e-11)
REACTOME_MAP_KINASES_ACTIVATION_IN_TLR_CASCADE | MEF2C MEF2A MAP2K6 [NAME] RPS6KA5 RPS6KA3 DUSP6 ATF1 PPP2R1B FOS |  | hsa-miR-181c (1.6e-12) hsa-miR-183 (2.6e-08) hsa-miR-142-5p (3.4e-08) hsa-miR-181a (1.1e-07) hsa-miR-20a (7.9e-06) hsa-miR-23b (1.2e-05) hsa-miR-145 (1.3e-05) hsa-miR-19b (0.0011) hsa-miR-424 (0.0033) hsa-miR-96 (0.0081) hsa-miR-19a (0.0088)
REACTOME_METABOLISM_OF_CARBOHYDRATES | RAE1 PHKG2 PHKA1 GCK ALDOA SEH1L SLC25A13 SLC25A10 NUP188 TPR PFKL GAPDH NUP155 NUP205 HK1 NUP214 NUP210 HK3 SLC2A1 NUP85 NUP98 NUP93 GOT1 PGLS PFKFB4 PFKFB2 NUP50 NUP62 GALK1 PGK1 NUPL1 PRPS2 GALE |  | hsa-miR-148a (1.7e-06) hsa-miR-185 (0.0055)
REACTOME_FURTHER_PLATELET_RELEASATE | TF CALM1 TTN HABP4 TLN1 SCG3 |  | hsa-miR-101 (6.2e-17) hsa-miR-770-5p (0.004)
REACTOME_OPIOID_SIGNALLING | PPP1R1B [NAME] GNAZ GNAL GNG13 GNG11 PDE1C PDE1A PPP2CB PPP3CA PRKAR2B PDE4C PPP2R1B ADCY3 ADCY4 ADCY8 ADCY6 POMC PLA2G4A ITPR1 ITPR2 [NAME] |  | hsa-miR-92 (1.2e-29) hsa-miR-145 (3.4e-14) hsa-miR-218 (1.2e-12) hsa-miR-335 (2e-09) hsa-miR-183 (7.7e-06) hsa-miR-92b (1.2e-05) hsa-miR-19b (1.5e-05) hsa-miR-485-3p (3.7e-05) hsa-miR-130a (4.4e-05) hsa-miR-106b (0.0026) hsa-miR-770-5p (0.0074) hsa-miR-20a (0.0082) hsa-miR-424 (0.0094)
REACTOME_TRANSPORT_OF_THE_SLBP_INDEPENDENT_MATURE_MRNA | RAE1 NCBP2 NCBP1 SEH1L NUP188 TPR NUP155 NUP205 NUP214 NUP210 NUP85 NUP98 NUP93 NUP50 NUP62 NUPL1 | * | hsa-miR-185 (7.4e-42) hsa-miR-125a (6e-07) hsa-miR-514 (2.3e-06) hsa-miR-93 (0.00027) hsa-miR-125b (0.0016)
REACTOME_COLLAGEN_MEDIATED_ACTIVATION_CASCADE | PDPK1 PIK3R5 SYK COL1A2 COL1A1 VAV3 VAV2 AKT1 |  | hsa-let-7f (0.0005)
REACTOME_HIV1_TRANSCRIPTION_ELONGATION | SSRP1 NCBP2 NCBP1 SUPT16H CTDP1 TH1L ERCC3 ERCC2 RDBP GTF2H4 GTF2H3 SUPT4H1 TCEB2 TCEB3 TCEB1 WHSC2 CDK7 ELL POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] | * | hsa-miR-496 (2.7e-18) hsa-miR-24 (1.8e-05) hsa-miR-30b (0.00067) hsa-miR-93 (0.0021) hsa-miR-302b (0.0032) hsa-miR-302a (0.0053)
REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY | PPP2R5D HLA-DQA2 RAC1 HLA-DOA THEM4 HLA-DQB1 PDPK1 GRB2 CD80 TRIB3 CTLA4 CDC42 SRC PTPN6 CD274 AKT1 PAK2 PAK1 CSK ICOSLG |  | hsa-miR-155 (0.00028) hsa-miR-1 (0.0022) hsa-let-7b (0.0022)
REACTOME_CD28_DEPENDENT_VAV1_PATHWAY | GRB2 CD80 CDC42 PAK2 PAK1 |  | hsa-miR-1 (2.5e-05) hsa-miR-185 (0.0011) hsa-let-7a (0.0023)
REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE | [NAME] GNAI1 CACNB2 GNG13 GNG11 ADRA2A ADRA2C CACNA1C |  | hsa-miR-19b (1.6e-34) hsa-miR-181c (3.4e-09) hsa-miR-485-3p (8e-08) hsa-miR-92 (3.2e-06) hsa-miR-19a (0.0016) hsa-miR-181b (0.0083)
REACTOME_ACTIVATED_TLR4_SIGNALLING | MYD88 SIGIRR IRAK4 IRAK1 IRF3 TIRAP |  | hsa-miR-142-3p (0.00015)
REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS | GRIK1 GRIK2 GRIK3 [NAME] |  | hsa-miR-181c (5.4e-15) hsa-miR-19b (6.8e-07) hsa-miR-218 (1.3e-05) hsa-miR-19a (0.00041)
REACTOME_FORMATION_OF_A_POOL_OF_FREE_40S_SUBUNITS | RPL18 [NAME] RPL13 RPL15 RPLP2 RPL10 FAU RPL11 [NAME] RPS14 [NAME] [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 RPL41 RPL37 RPL32 [NAME] RPL26 RPL27 RPL24 RPL29 RPL22 [NAME] RPL35A RPL6 RPL9 RPL3 RPL5 RPL10A RPL7A RPL4 RPL37A RPS3 RPS3A RPS4X RPS15A RPL13A RPL27A EIF3D EIF3G EIF3E EIF3F EIF3K | * | hsa-miR-142-5p (3.5e-75) hsa-miR-218 (4.3e-34) hsa-miR-376a (1.1e-26) hsa-miR-376b (1.8e-17) hsa-miR-137 (5.1e-14) hsa-miR-21 (9e-08) hsa-miR-135a (3e-05) hsa-miR-381 (3.6e-05)
REACTOME_METABOLISM_OF_RNA | RAE1 PABPC1 NCBP2 NCBP1 SNRPD3 SNRPD1 DDX6 TNKS1BP1 SEH1L NUP188 TPR GEMIN6 GEMIN7 GEMIN5 NUP155 WDR77 LSM5 LSM4 LSM2 EXOSC4 CNOT10 EXOSC5 EXOSC3 NUP205 NUP214 NUP210 RQCD1 CNOT3 CNOT6 NUP85 NUP98 NUP93 DCPS CLNS1A NUP50 NUP62 PARN NUPL1 SNRPB SNRPF SNRPE SNRPG EIF4G1 | * | hsa-miR-125a (3.1e-11) hsa-miR-125b (2.4e-08) hsa-miR-129-3p (1e-07) hsa-miR-148a (1.9e-07) hsa-miR-148b (1.7e-06) hsa-miR-186 (0.00034) hsa-miR-93 (0.0029)
REACTOME_RNA_POLYMERASE_III_TRANSCRIPTION | BRF2 GTF3C5 GTF3C2 GTF3C1 GTF3C4 [NAME] POLR2K POLR3H POLR3A POLR3D NFIC |  | hsa-let-7b (0.00056)
REACTOME_COMMON_PATHWAY | PF4V1 THBD FGA FGB PF4 F10 F13B PROS1 |  | hsa-miR-101 (3.8e-27) hsa-miR-144 (5.5e-16) hsa-miR-29c (1.4e-08) hsa-miR-29a (1.3e-05) hsa-miR-29b (0.00036)
REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | FBXO5 BTRC [NAME] PSMD11 PSMA6 PSMA5 PSMA4 PSMA3 FZR1 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] PSMB10 | * | hsa-miR-802 (8.4e-13) hsa-miR-30b (3.8e-12) hsa-miR-186 (3.6e-11) hsa-miR-146b (9.8e-09) hsa-miR-765 (1.4e-08) hsa-miR-30c (7.8e-06) hsa-miR-620 (0.0009) hsa-miR-30e-5p (0.0012) hsa-miR-555 (0.0026) hsa-miR-146a (0.0036) hsa-miR-212 (0.0047)
REACTOME_PI3K_AKT_SIGNALLING | RICTOR IRS2 IRS1 NR4A1 PTEN FOXO1 PIK3R1 |  | hsa-miR-181c (2.1e-08) hsa-miR-145 (2.6e-08) hsa-miR-181b (2.2e-05) hsa-miR-181a (0.00069) hsa-miR-20a (0.0012)
REACTOME_FGFR_LIGAND_BINDING_AND_ACTIVATION | FGF7 FGF9 FGF2 SDC2 KL FGF10 FGFR1 |  | hsa-miR-367 (6.4e-11) hsa-miR-92 (1.1e-09) hsa-miR-32 (3.4e-06) hsa-miR-218 (6.4e-06) hsa-miR-25 (0.00021) hsa-miR-15b (0.00039) hsa-miR-183 (0.0027) hsa-miR-96 (0.0099)
REACTOME_MITOTIC_PROMETAPHASE | [NAME] ZWINT AHCTF1 NDC80 KNTC1 ERCC6L MAD1L1 KIF2C NDE1 AURKB SEH1L DSN1 BIRC5 SPC25 [NAME] RANGAP1 CDCA8 NUF2 BUB1 BUB3 PLK1 SEC13 NUP98 MAD2L1 CDC20 PMF1 SGOL2 SGOL1 CKAP5 CASC5 BUB1B CENPA CENPO CENPN CENPL CENPP KIF18A CENPF CENPE CENPK CENPI | * | hsa-miR-129-3p (2.4e-09) hsa-miR-28 (0.00094) hsa-miR-603 (0.0072)
REACTOME_SIGNALING_BY_EGFR | HRAS MAPK1 AP2S1 [NAME] AP2B1 YWHAB GRB2 CLTC SHC1 MAP2K2 CDC42 STAM ADAM12 SRC EPS15L1 CSK |  | hsa-miR-185 (2.8e-05) hsa-let-7b (0.00042) hsa-miR-30c (0.0039) hsa-miR-148a (0.0073)
REACTOME_MYOGENESSIS | MEF2C MEF2A CTNNB1 MAP2K6 SPAG9 BNIP2 MYF6 CDH4 MAPK11 CDON BOC MYOG |  | hsa-miR-142-5p (1.1e-28) hsa-miR-19b (1.6e-15) hsa-miR-183 (5.4e-11) hsa-miR-23b (0.0018) hsa-miR-23a (0.0092) hsa-miR-19a (0.0097)
REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | RAC2 RAC1 ARHGEF11 RND1 CD72 SEMA4D ERBB2 CDC42 RHOC RHOG LIMK1 GRLF1 |  | hsa-miR-185 (0.004)
REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE_1 | [NAME] GNAI1 CACNB2 GNG13 GNG11 SNAP25 GNG10 [NAME] PRKAR2B VAMP2 KCNB1 PRKAR1A CACNA1C CACNA1A STXBP1 SYT5 ADCY8 ADCY5 ADCY6 RAPGEF3 ITPR1 ITPR2 RAP1A RAP1B |  | hsa-miR-181c (1.2e-10) hsa-miR-92 (4.4e-10) hsa-miR-367 (7.5e-07) hsa-miR-19b (8.7e-06) hsa-miR-149 (2.2e-05) hsa-miR-92b (0.00024) hsa-miR-130a (0.00029) hsa-miR-33 (0.0013) hsa-miR-19a (0.0019) hsa-miR-545 (0.0066)
REACTOME_RNA_POLYMERASE_I_III_AND_MITOCHONDRIAL_TRANSCRIPTION | HIST1H4K HIST1H4A HIST1H4B HIST1H4E HIST1H4F HIST1H4I HIST1H4J HIST1H4H HIST1H3J HIST1H3A [NAME] HIST1H3G HIST1H3H HIST1H3I GTF3C1 GTF3C4 H2BFS HIST3H2BB UBTF HIST2H2AA3 HIST1H2BO HIST1H2BM HIST1H2BN HIST1H2BK HIST1H2BL HIST1H2BI HIST1H2BJ H3F3A HIST2H2AC GTF2H3 HIST2H2BE HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2BB HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2AK CDK7 H2AFZ H2AFX SNAPC2 POLR1B POLR2H POLR2K POLR3H POLR3D TFB2M | * | hsa-miR-496 (2e-29) hsa-miR-802 (3.5e-17) hsa-miR-24 (2.9e-06) hsa-miR-584 (1.2e-05) hsa-let-7g (1.8e-05) hsa-let-7b (1.8e-05) hsa-miR-132 (0.00065) hsa-miR-659 (0.0052) hsa-miR-9 (0.0094)
REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES | GRIN2B [NAME] CACNB2 CACNB4 [NAME] GRIP2 [NAME] SNAP25 RPS6KA3 GNG10 GRIK1 GRIK2 GRIK3 NCALD RASGRF2 VAMP2 CACNA2D1 CACNA2D3 CACNA1A CACNA1B SLC1A7 DDC STXBP1 ADCY3 ADCY8 GRIA3 GRIA4 GRIA1 CALM1 GLS ALDH2 PLCB1 PRKCA SYN2 SLC17A7 |  | hsa-miR-92 (1.6e-11) hsa-miR-23b (7.1e-09) hsa-miR-92b (1.8e-08) hsa-miR-182 (6.9e-07) hsa-miR-335 (9.1e-07) hsa-miR-218 (5.9e-06) hsa-miR-19b (3.3e-05) hsa-miR-181c (5.6e-05) hsa-miR-301 (0.00022) hsa-miR-130a (0.00029) hsa-miR-130b (0.003) hsa-miR-543 (0.0079)
REACTOME_PHOSPHOLIPASE_CMEDIATED_CASCADE | FGF6 FGF7 FGF9 FGF1 FGF2 KL FGF10 FGFR2 FGFR1 |  | hsa-miR-183 (1.7e-17) hsa-miR-218 (1.1e-14) hsa-miR-543 (6.3e-08) hsa-miR-641 (1.3e-07) hsa-miR-199b (7.1e-07) hsa-miR-133b (0.0014) hsa-miR-338 (0.0048) hsa-miR-214 (0.0087)
REACTOME_SEMAPHORIN_INTERACTIONS | MET FES DPYSL2 SEMA5A SEMA6A SEMA6D SEMA3A FYN MYL9 |  | hsa-miR-145 (0.00016) hsa-miR-183 (0.0017) hsa-miR-23b (0.0019)
REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | RAE1 SEH1L NUP188 TPR NUP155 NUP205 NUP214 NUP210 NUP85 NUP98 NUP93 NUP50 NUP62 NUPL1 [NAME] | * | hsa-miR-185 (6.3e-35) hsa-miR-125a (1.2e-20) hsa-miR-125b (4.6e-14) hsa-miR-302c (2e-10) hsa-miR-148b (4.1e-08) hsa-miR-514 (1.3e-07) hsa-miR-93 (2e-06)
REACTOME_METABOLISM_OF_PROTEINS | TUBB2B RPL14 TUBB2A RPL13 RPL15 FAU RPL11 RPL12 RPS17 RPS14 [NAME] GAS6 RPS8 RPS7 PGAP1 EIF4A2 PFDN5 RPL32 [NAME] EIF5 RPS27A RPL35A FBXW7 RPL9 RPL3 RPL5 RPL10A RPL4 RPS3A RPS4X [NAME] SEMA6D TUBB6 EEF1B2 EIF3D EIF3F EIF3K EEF1A1 EIF4B PIGB PIGP PROS1 GSPT2 |  | hsa-miR-142-5p (1.4e-15) hsa-miR-367 (3.2e-12) hsa-miR-19b (1.9e-08) hsa-miR-218 (5e-08) hsa-miR-145 (2.9e-07) hsa-miR-23b (9.3e-06) hsa-miR-23a (4.1e-05) hsa-miR-376b (9.6e-05) hsa-miR-335 (0.00056) hsa-miR-19a (0.0018) hsa-miR-181c (0.0028) hsa-miR-101 (0.0044) hsa-miR-26a (0.0095)
REACTOME_SIGNALING_BY_BMP | FSTL1 NOG BMP2 [NAME] CHRDL1 GREM2 ACVR2A BMPR1A |  | hsa-miR-181c (8.2e-13) hsa-miR-23b (1.2e-06) hsa-miR-145 (2.7e-06) hsa-miR-429 (6.3e-05) hsa-miR-92 (9.3e-05) hsa-miR-181b (0.0003) hsa-miR-32 (0.00038) hsa-miR-181a (0.00097) hsa-miR-15a (0.0018)
REACTOME_HOMOLOGOUS_RECOMBINATION_REPAIR | [NAME] RAD51 [NAME] |  | hsa-miR-24 (0.00095)
REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL | IGKV1-5 KLRC1 IGKC CD200 CD200R1 C3 VCAM1 LILRA1 CD40 LILRB5 CD34 ICAM2 CD160 AMICA1 KIR2DL2 KLRK1 ITGB1 |  | hsa-miR-29a (0.0039)
REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS | GNGT1 GNGT2 GNA15 GNA12 F2RL2 GNG5 GNB2 GNB1 GNB3 F2R |  | hsa-let-7b (0.0093)
REACTOME_TRANSLATION | RPL18 [NAME] RPL13 RPL15 RPLP2 RPL10 FAU RPL11 [NAME] RPS14 [NAME] [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 RPL41 EIF4A2 EEF1G RPL37 RPL32 [NAME] [NAME] ETF1 RPL29 RPL22 RPL21 EIF5 RPS27A RPL35A RPL6 RPL9 RPL3 RPL5 RPL10A RPL7A RPL4 RPL37A RPS3 RPS3A RPS4X RPS15A RPL13A RPL27A EIF2B1 EEF1B2 EIF3D EIF3G EIF3E EIF3F EIF3K EEF1A1 EIF4B GSPT2 | * | hsa-miR-19b (3.5e-23) hsa-miR-142-5p (3.7e-20) hsa-miR-181c (1.9e-15) hsa-miR-376a (5.1e-14) hsa-miR-135b (2.2e-13) hsa-miR-149 (1.1e-11) hsa-miR-181a (2.5e-11) hsa-miR-376b (4.2e-07) hsa-miR-183 (6.3e-07) hsa-miR-181b (1.1e-06) hsa-miR-543 (1.6e-05) hsa-miR-335 (1.8e-05) hsa-miR-33 (1.8e-05) hsa-miR-144 (8.1e-05) hsa-miR-218 (8.4e-05) hsa-miR-15b (0.00013) hsa-miR-16 (0.00023) hsa-miR-101 (0.00074) hsa-miR-137 (0.0022)
REACTOME_GS_ALPHA_MEDIATED_EVENTS_IN_GLUCAGON_SIGNALLING | [NAME] GNG13 GNG11 GNG10 ADCY3 ADCY4 ADCY8 ADCY5 ADCY6 |  | hsa-miR-19b (1.7e-06) hsa-miR-335 (0.00023) hsa-miR-25 (0.0005) hsa-miR-92 (0.00066) hsa-miR-101 (0.00092) hsa-miR-367 (0.00096) hsa-miR-19a (0.0095)
REACTOME_SCF_SKP2_MEDIATED_DEGRADATION_OF_P27_P21 | [NAME] [NAME] PSMD13 PSMD12 PSMD11 PSMA6 PSMA5 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] PSMB10 | * | hsa-miR-186 (8.2e-15) hsa-miR-146a (6.4e-13) hsa-miR-146b (1.6e-12) hsa-miR-802 (1.1e-11) hsa-miR-302a (1.1e-07) hsa-miR-30c (1.9e-07) hsa-miR-515-5p (1.1e-06) hsa-miR-138 (5.6e-06) hsa-miR-30b (5.1e-05) hsa-miR-212 (0.00021) hsa-miR-765 (0.0004) hsa-miR-34a (0.00087) hsa-miR-7 (0.0016) hsa-miR-302b (0.0089)
REACTOME_VPR_MEDIATED_NUCLEAR_IMPORT_OF_PICS | RAE1 SEH1L NUP188 TPR NUP155 NUP205 NUP214 NUP210 NUP85 NUP98 NUP93 NUP50 NUP62 NUPL1 KPNA1 | * | hsa-miR-185 (1.8e-29) hsa-miR-514 (1.2e-11) hsa-miR-125a (4.3e-08) hsa-miR-93 (8.6e-07)
REACTOME_DEPOLARIZATION_OF_THE_PRESYNAPTIC_TERMINAL_TRIGGERS_THE_OPENING_OF_CALCIUM_CHANNELS | CACNB1 CACNB2 CACNB4 CACNA2D1 CACNA2D3 CACNA1A CACNA1B |  | hsa-miR-181c (2.4e-12) hsa-miR-103 (2e-06) hsa-miR-23b (6.8e-06) hsa-miR-183 (8e-06) hsa-miR-543 (5.7e-05) hsa-miR-181b (0.00062) hsa-miR-181a (0.0011) hsa-miR-101 (0.0031)
REACTOME_PACKAGING_OF_TELOMERE_ENDS | HIST1H4K HIST1H4A HIST1H4B HIST1H4E HIST1H4F HIST1H4I HIST1H4J HIST1H4H H2BFS HIST3H2BB HIST3H3 HIST2H2AA3 [NAME] HIST1H2BM HIST1H2BN HIST1H2BK HIST1H2BL HIST1H2BI HIST1H2BJ HIST2H2AC HIST2H2BE HIST1H2AB HIST1H2AC HIST1H2AD HIST1H2AE HIST1H2BB HIST1H2BD HIST1H2BE HIST1H2BF HIST1H2BG HIST1H2BH HIST1H2AK [NAME] | * | hsa-miR-802 (1.3e-52) hsa-miR-24 (3.1e-15) hsa-miR-544 (0.00094) hsa-miR-9 (0.0071) hsa-miR-584 (0.0096)
REACTOME_SHC_RELATED_EVENTS | HRAS MAPK1 NRAS KRAS [NAME] | * | hsa-miR-346 (1.4e-09) hsa-miR-217 (1.4e-09) hsa-miR-30b (6.4e-09) hsa-let-7g (9.5e-06) hsa-let-7a (1e-05) hsa-miR-148b (9.1e-05) hsa-let-7b (0.00029) hsa-miR-155 (0.00056) hsa-miR-30c (0.001) hsa-miR-28 (0.0015) hsa-miR-152 (0.0022) hsa-miR-132 (0.0023) hsa-let-7f (0.0051) hsa-miR-190 (0.0081)
REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC:ORIGIN_COMPLEX | E2F2 E2F3 ORC1L CDC6 ORC6L ORC5L ORC2L MCM8 | * | [NAME] (1.9e-09) hsa-miR-125a (4.1e-07) hsa-miR-34a (0.00011) hsa-miR-125b (0.00015) hsa-miR-152 (0.00032) hsa-miR-185 (0.00097) hsa-miR-200a (0.0012) hsa-miR-30c (0.0012) hsa-miR-148b (0.0022) hsa-miR-194 (0.0024) hsa-miR-30e-5p (0.0066)
REACTOME_GAP_JUNCTION_TRAFFICKING | AP2M1 [NAME] MYO6 |  | hsa-miR-206 (0.0066)
REACTOME_IRS_RELATED_EVENTS | RPS6 FGF7 FGF9 FGF2 PDE3B IRS2 IRS1 [NAME] FGF10 FGFR1 [NAME] |  | hsa-miR-92 (5e-10) hsa-miR-145 (5.6e-09) hsa-miR-181c (1e-08) hsa-miR-181a (4.4e-07) hsa-miR-32 (6e-05) hsa-miR-367 (0.00047) hsa-miR-181b (0.0012) hsa-miR-641 (0.0046)
REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | FURIN DOHH DHPS PLAUR GPAA1 DPM2 PIGM PIGC PIGX PIGU PIGT PIGQ PIGO PIGN |  | hsa-miR-185 (0.0094)
REACTOME_MTOR_SIGNALLING | RPS6 [NAME] |  | hsa-miR-145 (9e-06) hsa-miR-367 (0.00095)
REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION | [NAME] GNG13 GNG11 GNG10 PRKAR2B PRKAR1A ADCY3 ADCY4 ADCY8 ADCY5 ADCY6 |  | hsa-miR-92 (3.7e-08) hsa-miR-335 (3.4e-07) hsa-miR-19b (0.0022) hsa-miR-367 (0.0036)
REACTOME_TCR_SIGNALING | PIK3CB HLA-[NAME] WAS CARD11 HLA-DQB1 ENAH RELA IKBKG IKBKB PDPK1 FYB PIK3R2 VASP RIPK2 EVL PAK2 PAK1 CSK |  | hsa-miR-30b (1.1e-05) hsa-miR-320 (0.0065)
REACTOME_DNA_REPLICATION_PRE_INITIATION | DBF4 E2F2 E2F3 RPA3 ORC1L CDC7 CDC6 POLA1 POLA2 POLE2 ORC6L ORC5L ORC2L PRIM2 POLE CDT1 PSMD14 PSMD13 PSMD11 MCM10 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC2 MCM8 PSMD1 PSMD2 PSMD3 PSMD4 PSMD8 MCM2 MCM3 MCM4 MCM6 [NAME] | * | hsa-miR-186 (2.4e-72) hsa-miR-30b (2.8e-23) hsa-miR-328 (1.2e-22) hsa-miR-185 (3.3e-21) hsa-miR-802 (5.9e-19) hsa-miR-125b (3.8e-16) hsa-miR-515-5p (3.7e-14) hsa-miR-146b (4.1e-14) hsa-miR-555 (4.6e-13) hsa-miR-210 (1.5e-11) hsa-miR-1 (6.8e-11) hsa-miR-125a (2.3e-07) hsa-miR-34a (5.1e-07) hsa-miR-146a (6.4e-06) hsa-miR-148b (1.9e-05) hsa-miR-152 (2.3e-05) hsa-miR-30a-3p (0.00033) hsa-miR-128b (0.00051) hsa-miR-643 (0.00066) hsa-miR-342 (0.00079) hsa-miR-767-3p (0.0012) hsa-miR-200a (0.0014) hsa-miR-30d (0.0075) hsa-miR-765 (0.0084) hsa-miR-148a (0.0086) hsa-miR-620 (0.0093)
REACTOME_PYRUVATE_METABOLISM_AND_TCA_CYCLE | LDHB PDK4 SDHD SUCLA2 SUCLG2 SUCLG1 |  | hsa-miR-181c (0.00067) hsa-miR-15a (0.00099)
REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12 | [NAME] GNG13 GNG11 P2RY12 |  | hsa-miR-485-3p (1.8e-07) hsa-miR-19b (9.9e-06) hsa-miR-218 (2.2e-05) hsa-miR-19a (0.0001)
REACTOME_BASE_EXCISION_REPAIR | [NAME] NTHL1 FEN1 OGG1 CCNO MPG XRCC1 POLD4 POLD1 POLD2 TDG SMUG1 POLB | * | hsa-let-7b (5.3e-09) hsa-miR-125a (1.9e-06) hsa-miR-30b (0.00069) hsa-miR-30d (0.0019) hsa-miR-30c (0.0089)
REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | ARHGEF18 ARHGEF16 ARHGEF11 FGD3 [NAME] ARHGEF2 RASGRF1 VAV3 VAV2 TRIO AATF ECT2 |  | hsa-miR-1 (0.00031)
REACTOME_EXTENSION_OF_TELOMERES | LIG1 FEN1 DKC1 RPA3 PCNA RUVBL2 RUVBL1 POLA1 POLA2 POLE2 POLD4 POLD1 POLD2 PRIM2 POLE RFC5 RFC3 RFC4 RFC2 | * | hsa-miR-154 (2.5e-14) hsa-miR-217 (1e-13) hsa-miR-1 (1.1e-08) hsa-miR-610 (8e-08) hsa-miR-515-5p (2.6e-05)
REACTOME_REMOVAL_OF_DNA_PATCH_CONTAINING_ABASIC_RESIDUE | NTHL1 FEN1 OGG1 CCNO MPG POLD4 POLD1 POLD2 TDG SMUG1 POLB | * | hsa-miR-30b (1.8e-05) hsa-miR-1 (0.0016) hsa-miR-125a (0.0089)
REACTOME_TRANSLATION_INITIATION_COMPLEX_FORMATION | FAU RPS18 RPS17 RPS14 [NAME] [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 EIF4A2 RPS27A RPS3 RPS3A RPS4X RPS15A EIF3D EIF3G EIF3E EIF3F [NAME] | * | hsa-miR-142-5p (8.4e-40) hsa-miR-19b (3.9e-33) hsa-miR-145 (5.4e-23) hsa-miR-149 (1.6e-17) hsa-miR-181a (9.4e-17) hsa-miR-543 (1.8e-14) hsa-miR-335 (7.1e-11) hsa-miR-15a (2.3e-09) hsa-miR-183 (9.4e-08) hsa-miR-181c (2.7e-06) hsa-miR-218 (3.5e-05) hsa-miR-19a (5.5e-05) hsa-miR-135b (0.00014) hsa-miR-16 (0.00017) hsa-miR-103 (0.0007) hsa-miR-137 (0.00098)
REACTOME_STRIATED_MUSCLE_CONTRACTION | [NAME] TNNI2 VIM NEB DMD MYBPC2 MYBPC1 TTN TNNT3 MYL2 MYL3 MYL1 TPM2 TPM1 |  | hsa-miR-181c (5.8e-14) hsa-miR-101 (1.4e-06) hsa-miR-137 (2.5e-06)
[NAME] | HRAS MAPK1 SPP1 NRAS FURIN COL5A2 COL5A1 KRAS YWHAB PDGFB [NAME] PIK3R2 MAP2K2 COL1A2 COL1A1 THBS1 THBS2 STAT1 STAT3 SRC |  | hsa-let-7f (0.0007) hsa-miR-320 (0.0015) hsa-miR-148a (0.0027) hsa-let-7a (0.0037)
REACTOME_CELL_CYCLE_CHECKPOINTS | RAD1 DBF4 MAD1L1 ANAPC2 ANAPC7 HUS1 CLSPN ATRIP UBE2C [NAME] [NAME] CDC7 CDC6 BUB3 CCNB1 CCNB2 ORC6L RFWD2 ORC5L ORC2L CDC25C CDC25A MAD2L1 RFC4 RFC2 CHEK1 CDC20 PSMD14 PSMD13 PSMD11 MCM10 PSMA6 PSMA4 PSMA3 ANAPC11 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC2 MCM8 PSMD1 PSMD2 PSMD3 PSMD4 PSMD8 MCM2 MCM3 MCM4 MCM6 [NAME] | * | hsa-miR-30b (6.3e-53) hsa-miR-186 (5.5e-33) hsa-miR-138 (3.1e-20) hsa-miR-146b (5.3e-16) hsa-miR-802 (1.3e-14) hsa-miR-643 (2.1e-10) hsa-miR-30a-3p (6.1e-09) hsa-miR-30e-3p (6e-08) hsa-miR-767-3p (1.1e-06) hsa-miR-146a (1.4e-06) hsa-miR-515-5p (1.8e-06) hsa-miR-555 (2.2e-06) hsa-let-7b (1.4e-05) hsa-let-7a (0.00023) hsa-miR-26b (0.00069) hsa-miR-30e-5p (0.0008) hsa-let-7f (0.00086) hsa-miR-503 (0.00095) hsa-let-7i (0.0019) hsa-miR-30c (0.0034) hsa-miR-195 (0.0035) hsa-let-7c (0.0074)
REACTOME_PLATELET_DEGRANULATION | A2M F8 SERPING1 GAS6 SELP IGF1 FGA EGF PF4 FIGF CFD VEGFC CD36 PPBP [NAME] PDGFA MMRN1 TTN CLU ALB SRGN HABP4 TLN1 PROS1 SCG3 HRG VWF |  | hsa-miR-101 (1e-14) hsa-miR-144 (1.7e-13) hsa-miR-106b (2e-07) hsa-miR-770-5p (3.4e-05) hsa-miR-20b (0.0011) hsa-miR-130a (0.0059)
REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE | A2M F8 SERPING1 F7 F3 TFPI PF4V1 [NAME] PF4 F10 F13B PROS1 VWF |  | hsa-miR-101 (3.5e-24) hsa-miR-19b (1.2e-17) hsa-miR-19a (1.9e-16) hsa-miR-144 (4.8e-05) hsa-miR-29b (0.0041)
REACTOME_PLC_BETA_MEDIATED_EVENTS | [NAME] PRKAR2B ADCY3 [NAME] PLA2G4A ITPR1 ITPR2 [NAME] |  | hsa-miR-19b (5.5e-15) hsa-miR-92 (2.6e-10) hsa-miR-335 (3e-07) hsa-miR-92b (4.9e-05) hsa-miR-130a (6.1e-05) hsa-miR-32 (7.6e-05) hsa-miR-25 (0.0013) hsa-miR-103 (0.0013) hsa-miR-770-5p (0.0019) hsa-miR-16 (0.0066)
REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | APOA4 APOB HSPG2 LPL LIPC |  | hsa-miR-149 (0.003)
REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | ARF1 [NAME] RAB5C CLTC TGOLN2 AP1S3 AP1S1 DNM2 AP1G1 IGF2R AP1M1 AP1M2 AP1B1 AP3B1 NAPA |  | [NAME] (5.9e-06) hsa-miR-299-3p (2.8e-05) hsa-miR-30b (3.1e-05) hsa-miR-320 (5.6e-05) hsa-miR-125b (0.00018) hsa-miR-152 (0.00065) hsa-miR-30c (0.0021) hsa-miR-9 (0.0024) hsa-miR-138 (0.0027) hsa-miR-30e-5p (0.0027)
REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE | [NAME] SNAP25 VAMP2 STXBP1 |  | hsa-miR-130b (7.6e-06) hsa-miR-218 (2.6e-05) hsa-miR-92 (0.0024) hsa-miR-130a (0.0027)
REACTOME_CELLEXTRACELLULAR_MATRIX_INTERACTIONS | ARHGEF6 FLNC PARVA PXN LIMS2 ITGB1 |  | hsa-miR-145 (6.4e-13) hsa-miR-218 (8.2e-11) hsa-miR-183 (3.8e-09) hsa-miR-19b (1.1e-05) hsa-miR-29b (0.0014) hsa-miR-19a (0.0016)
[NAME] | ANAPC2 ANAPC7 UBE2C PSMD14 PSMD13 PSMD11 PSMA6 PSMA4 PSMA3 FZR1 ANAPC11 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] | * | hsa-miR-802 (7.8e-10) hsa-miR-186 (1.9e-08) hsa-miR-30b (9.9e-08) hsa-miR-146b (2.9e-06) hsa-miR-146a (0.0012) hsa-miR-620 (0.0027) hsa-miR-515-5p (0.0082)
REACTOME_SYNTHESIS_OF_DNA | LIG1 FEN1 RPA3 CCNA2 ORC1L PCNA CDC6 POLA1 POLA2 POLE2 ORC6L GINS1 GINS2 GINS4 POLD4 POLD1 POLD2 CDK2 ORC5L ORC2L PRIM2 POLE RFC5 RFC3 RFC4 RFC2 CDT1 PSMD14 PSMD13 PSMD12 PSMD11 PSMA6 PSMA4 PSMA3 FZR1 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 MCM8 PSMD1 PSMD2 PSMD3 PSMD4 PSMD8 MCM2 MCM3 MCM4 [NAME] [NAME] PSMB10 | * | hsa-miR-802 (1.8e-22) hsa-miR-555 (3.2e-17) hsa-miR-186 (1.1e-16) hsa-miR-146b (1.2e-14) hsa-miR-185 (2.3e-10) hsa-miR-515-5p (1.5e-09) hsa-miR-30b (8.9e-08) hsa-miR-206 (2.6e-06) hsa-miR-30c (7.6e-06) hsa-miR-767-3p (1.4e-05) hsa-miR-1 (4.3e-05) hsa-miR-328 (0.00032) hsa-miR-132 (0.00044) hsa-miR-212 (0.0018) hsa-miR-620 (0.0024) hsa-miR-765 (0.004) hsa-miR-146a (0.0071) hsa-miR-30a-5p (0.0091)
REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | GNAL ADCY3 ADCY4 ADCY8 ADCY5 ADCY6 |  | hsa-miR-335 (2.6e-08) hsa-miR-92 (6.9e-07) hsa-miR-19b (0.00068) hsa-miR-92b (0.0045)
REACTOME_PHASE_1_FUNCTIONALIZATION_OF_COMPOUNDS | PTGS2 MAOA MAOB FMO2 ADH1C ADH1B ADH1A CYP2U1 ALDH1A1 ADH4 CYP3A4 CYP3A5 CYP3A7 CYP39A1 PTGIS ALDH2 CYP11A1 CYP26B1 | * | hsa-miR-149 (2.4e-36) hsa-miR-144 (1.5e-31) hsa-miR-101 (9.6e-31) hsa-miR-15b (5.7e-16) hsa-miR-15a (1.1e-08) hsa-miR-20a (1.9e-08) hsa-miR-16 (0.009)
REACTOME_DNA_STRAND_ELONGATION | [NAME] FEN1 RPA3 PCNA POLA1 POLA2 GINS1 GINS2 GINS4 POLD4 POLD1 POLD2 PRIM2 RFC5 RFC3 RFC4 RFC2 MCM8 MCM2 MCM3 MCM4 [NAME] | * | hsa-miR-154 (3.8e-19) hsa-miR-1 (4.7e-11) hsa-miR-217 (4.6e-09) hsa-miR-206 (0.0015)
REACTOME_RNA_POLYMERASE_I_TRANSCRIPTION_INITIATION | [NAME] ERCC2 RRN3 GTF2H4 GTF2H3 CDK7 POLR1A POLR1B POLR2H POLR2K |  | hsa-miR-496 (0.0076)
REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS | RAC2 RAC1 ARHGEF18 ARHGEF16 ARHGEF11 GNA12 FGD3 [NAME] ARHGEF1 RASGRF1 VAV3 VAV2 CDC42 RHOC RHOG TRIO ECT2 |  | hsa-miR-132 (0.0078)
REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | HIST1H1E HIST1H1D HIST1H1C HIST1H1B DFFA DFFB CASP3 H1F0 KPNB1 KPNA1 |  | hsa-miR-152 (1.5e-06) hsa-miR-302a (3.4e-06) hsa-miR-155 (2.6e-05) hsa-let-7b (0.00012) hsa-miR-148b (0.00019) hsa-miR-30b (0.0039)
REACTOME_PLATELET_ACTIVATION | A2M GNG2 GNG7 F8 SERPING1 GNAI1 [NAME] GNG13 GNG11 DGKB SELP IGF1 DGKI P2RY12 GNG10 FGA EGF P2RX1 PF4 FIGF CFD VEGFC CD36 PPBP PLA2G4A TF ITPR1 ITPR2 [NAME] PDGFA MMRN1 TTN CLU ALB SRGN PLCG2 HABP4 TLN1 MGLL AKT3 PRKCA PROS1 SCG3 HRG PIK3R1 VWF |  | hsa-miR-181c (1.1e-14) hsa-miR-144 (7.3e-09) hsa-miR-20a (4.6e-05) hsa-miR-218 (0.00018) hsa-miR-19a (0.00083) hsa-miR-130b (0.0016) hsa-miR-106b (0.0021) hsa-miR-485-3p (0.0039) hsa-miR-130a (0.0043)
REACTOME_CELL_JUNCTION_ORGANIZATION | CTNNB1 PVRL3 ARHGEF6 FLNC PARVA CDH12 CDH13 CDH10 CLDN8 CLDN5 CLDN2 CDH3 CDH4 CDH6 [NAME] LAMC2 PXN LAMB3 LAMA3 PARD3 LIMS2 CLDN19 CLDN10 CLDN11 CLDN23 DST ITGB4 ITGB1 PARD6G |  | hsa-miR-92 (1.3e-16) hsa-miR-367 (1.2e-15) hsa-miR-32 (1.5e-11) hsa-miR-181a (7.6e-10) hsa-miR-137 (1.3e-08) hsa-miR-145 (3e-08) hsa-miR-183 (2.6e-06) hsa-miR-768-3p (4.5e-06) hsa-miR-218 (0.00014) hsa-miR-424 (0.00057) hsa-miR-181c (0.0014) hsa-miR-106b (0.0018) hsa-miR-20a (0.0078)
REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING | RAC1 ARHGEF18 ARHGEF16 ARHGEF11 RELA FGD3 ARHGDIA HDAC1 IKBKB PREX1 CASP3 CASP2 BAD MYD88 PSENEN MCF2L IRAK1 PRKCI MAGED1 SORCS3 ARHGEF2 ARHGEF1 RASGRF1 VAV3 VAV2 APH1A SMPD2 TRIO PSEN1 PSEN2 SQSTM1 AATF RIPK2 ECT2 |  | hsa-miR-9 (1.2e-05) hsa-miR-34a (0.0001) hsa-miR-146b (0.00032) hsa-miR-146a (0.0016) hsa-miR-133b (0.0069) hsa-miR-133a (0.0093)
REACTOME_SHC_MEDIATED_SIGNALLING | HRAS MAPK1 NRAS KRAS [NAME] | * | hsa-miR-217 (2.1e-12) hsa-let-7f (2.7e-11) hsa-miR-155 (8.2e-06) hsa-miR-148a (1.2e-05) hsa-miR-30b (0.00018) hsa-miR-132 (0.00051) hsa-miR-346 (0.001) hsa-miR-148b (0.0011) hsa-let-7b (0.0026) hsa-miR-30c (0.0077)
REACTOME_APOPTOTIC_EXECUTION_PHASE | HIST1H1D HIST1H1C HIST1H1B PTK2 [NAME] DBNL LMNB1 CLSPN OCLN PRKCD STK24 PAK2 [NAME] |  | hsa-let-7b (0.00023) hsa-miR-30c (0.0069)
REACTOME_HIV_INFECTION | RAE1 LIG1 RAC1 ARF1 AP2S1 TAF10 TAF13 TAF12 FEN1 SSRP1 NCBP2 NCBP1 AP2M1 CCR5 BANF1 SUPT16H AP2B1 SEH1L CTDP1 AP2A2 PACS1 TH1L PPIA NUP188 CXCR4 RANBP1 TPR ERCC2 [NAME] AP1S3 AP1S1 GTF2H4 GTF2H3 NUP205 NUP214 NUP210 TCEB2 TCEB3 [NAME] GTF2E1 [NAME] TAF4 TAF5 WHSC2 GTF2A1 ATP6V1H NUP85 [NAME] HCK ELL NUP50 NUP62 AP1B1 RNGTT POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] PSMD11 NUPL1 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC3 PSMC2 PAK2 PSMD1 PSMD2 PSMD3 PSMD4 KPNB1 PSMD8 [NAME] PSMB10 | * | hsa-miR-186 (5.7e-24) hsa-miR-148a (7.8e-19) hsa-miR-132 (8.6e-15) hsa-miR-146a (8.3e-13) hsa-miR-30b (7.7e-12) hsa-miR-146b (2.6e-10) hsa-miR-152 (5e-08) hsa-miR-802 (6.9e-08) hsa-miR-328 (9.4e-07) hsa-miR-320 (2.3e-06) hsa-miR-148b (2e-05) hsa-miR-200a (2.3e-05) hsa-miR-125b (5.1e-05) hsa-miR-496 (8.9e-05) hsa-miR-555 (0.00014) hsa-miR-299-3p (0.00017) hsa-miR-30c (0.00031) hsa-miR-212 (0.00034) hsa-miR-34a (0.0015) hsa-miR-302c (0.0023) hsa-miR-302a (0.003) hsa-miR-185 (0.0043) hsa-let-7f (0.0049) hsa-miR-495 (0.0077)
REACTOME_CHOLESTEROL_BIOSYNTHESIS | PMVK [NAME] HSD17B7 DHCR24 |  | hsa-miR-205 (0.00069)
REACTOME_SEROTONIN_RECEPTORS | HTR1B HTR1E HTR5A HTR2B HTR2C HTR2A HTR4 HTR7 |  | hsa-miR-23b (6.5e-09) hsa-miR-218 (0.0026) hsa-miR-15b (0.0087)
REACTOME_P38MAPK_EVENTS | HRAS NRAS RALA MAPKAPK3 MAPKAPK2 KRAS RALGDS MAPK12 MAPK13 SRC |  | hsa-miR-1 (5.8e-09) hsa-miR-217 (2.9e-07) hsa-let-7a (2.9e-05) hsa-miR-30b (0.00011) hsa-let-7f (0.00012) hsa-let-7i (0.0091)
REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS | CTNNB1 PVRL3 CDH12 CDH13 CDH10 CDH3 CDH4 CDH6 CDH9 |  | hsa-miR-367 (2.4e-14) hsa-miR-183 (1.8e-06)
REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | FES SEMA3A FYN |  | hsa-miR-92 (1.7e-16) hsa-miR-145 (1.3e-11) hsa-miR-32 (2.2e-07) hsa-miR-586 (0.0015)
REACTOME_CELL_CYCLE_MITOTIC | PPP2R5D INCENP LIG1 RCC2 ZWINT AHCTF1 NDC80 TSGA14 FEN1 [NAME] DBF4 KNTC1 TUBG1 ERCC6L [NAME] MAD1L1 E2F3 E2F5 KIF2C NDE1 AURKA AURKB ANAPC2 TUBA4A ANAPC7 NEK2 FBXO5 ALMS1 CEP250 SEH1L DSN1 CETN2 BIRC5 YWHAG KIF20A CEP78 PKMYT1 RAD21 FGFR1OP SPC25 UBE2C APITD1 RPA3 TYMS MLF1IP TUBGCP2 TUBB2C RANGAP1 CDCA8 ORC1L PCNT NUF2 PCNA CCNE2 CCNE1 CDC7 CDC6 CCND1 RRM2 [NAME] BUB1 BUB3 CCNB1 CCNB2 XPO1 BTRC AZI1 TUBB POLE2 ORC6L GINS1 GINS2 GINS4 POLD4 PLK4 PLK1 POLD1 SEC13 NUP85 [NAME] NUP98 ORC2L ODF2 CDC25C CDC25A CDC25B PTTG1 PRIM2 POLE MAD2L1 RFC4 RFC2 CEP164 CDC20 PMF1 CDT1 PSMD14 PSMD13 PSMD11 MCM10 SGOL2 SGOL1 PSMA6 PSMA4 PSMA3 FZR1 ANAPC11 PSMA7 PSMB4 PSMB3 PSMB2 CKAP5 CASC5 PSMC4 PSMC2 MCM8 PSMD1 PSMD2 PSMD3 PSMD4 PSMD8 MCM2 MCM3 MCM4 MCM6 [NAME] CENPA CENPO CENPN CENPM CENPL CENPP KIF18A CENPF CENPE CENPK CENPI | * | hsa-miR-146b (1.1e-19) hsa-miR-186 (1.8e-19) hsa-miR-802 (3.8e-12) hsa-let-7f (3.7e-10) hsa-miR-496 (4e-10) hsa-miR-30b (1.1e-08) hsa-miR-152 (1.9e-08) hsa-miR-148b (5.9e-08) hsa-miR-555 (2e-07) hsa-miR-328 (3.5e-07) hsa-miR-302c (2.5e-06) hsa-let-7b (4.5e-06) hsa-miR-132 (8e-06) hsa-miR-200a (1.2e-05) hsa-miR-185 (1.4e-05) hsa-miR-620 (2.1e-05) hsa-miR-302a (5.9e-05) hsa-miR-146a (9.4e-05) hsa-miR-30e-3p (9.6e-05) hsa-miR-30d (0.00062) hsa-miR-372 (0.0027) hsa-miR-125b (0.0031) hsa-miR-30c (0.004) hsa-miR-148a (0.01)
REACTOME_DNA_REPAIR | [NAME] XAB2 NTHL1 FANCD2 FEN1 OGG1 PALB2 DDB1 [NAME] ZBTB32 FANCI FANCF FANCG FANCA CCNO FANCB FANCC RAD51 BRCA2 BRCA1 UBE2T PRKDC RPA3 ERCC4 ERCC1 ERCC2 MPG XRCC4 XRCC1 PCNA GTF2H4 GTF2H3 POLE2 POLD4 POLD1 POLD2 TDG NBN CDK7 SMUG1 H2AFX POLE POLB RFC5 RFC3 RFC4 RFC2 MAD2L2 POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] TDP1 | * | hsa-miR-496 (4.5e-12) hsa-miR-154 (4.3e-07) hsa-miR-217 (9.1e-07) hsa-miR-30b (9.1e-06) hsa-miR-1 (0.00021) hsa-miR-30d (0.0016) hsa-miR-30c (0.007)
REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | AUH [NAME] [NAME] BCKDHB HIBCH |  | hsa-miR-19a (9e-07) hsa-miR-19b (4.6e-06) hsa-miR-23b (1.2e-05)
REACTOME_CAM_PATHWAY | PDE1C PDE1A PRKAR2B PRKAR1A ADCY3 ADCY4 ADCY8 ADCY5 ADCY6 [NAME] |  | hsa-miR-335 (3.8e-10) hsa-miR-92 (7.1e-09) hsa-miR-19b (1.6e-05) hsa-miR-101 (2.1e-05) hsa-miR-367 (0.00017) hsa-miR-25 (0.00041) hsa-miR-218 (0.00068) hsa-miR-92b (0.0022) hsa-miR-133a (0.0041) hsa-miR-770-5p (0.0047)
REACTOME_METABLISM_OF_NUCLEOTIDES | ADSS SLC29A2 GART DGUOK TXN CAD IMPDH1 TXNRD1 ATIC NT5C3 PPAT TK1 APRT AK2 TYMS NME4 NME1 RRM2 RRM1 CTPS2 DCK NT5M GMPS HPRT1 PAICS CTPS DTYMK GUK1 GSR UCK2 |  | hsa-miR-125b (1.7e-10) hsa-miR-148b (1.5e-06) hsa-let-7f (0.00064) hsa-miR-148a (0.0022) hsa-miR-125a (0.0023)
REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | FAU RPS18 RPS17 RPS14 [NAME] [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 RPS27A RPS3 RPS3A RPS4X RPS15A EIF3D EIF3G EIF3E EIF3F EIF3K | * | hsa-miR-218 (2.2e-29) hsa-miR-142-5p (1.9e-26) hsa-miR-137 (4.2e-15) hsa-miR-135b (4.2e-12)
REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE | FEN1 RPA3 PCNA POLA1 POLA2 POLD4 POLD1 PRIM2 |  | hsa-miR-1 (5.9e-09) hsa-miR-154 (1.2e-08) hsa-miR-610 (0.004) hsa-miR-217 (0.0059)
REACTOME_COPI_MEDIATED_TRANSPORT | ARF1 ARFGAP1 COPA COPG COPE COPB2 COPB1 COPZ1 | * | hsa-miR-142-3p (0.00017) hsa-miR-138 (0.0066)
REACTOME_METABOLISM_OF_MRNA | PABPC1 PAIP1 EDC3 DDX6 TNKS1BP1 LSM5 LSM4 LSM2 LSM1 EXOSC4 CNOT10 EXOSC5 EXOSC3 RQCD1 CNOT3 CNOT6 DCPS DCP2 PARN EIF4G1 |  | hsa-miR-802 (2.7e-11) hsa-miR-125a (2.6e-07) hsa-miR-30b (0.00057) hsa-miR-186 (0.00095) hsa-miR-125b (0.0018) hsa-miR-152 (0.0028) hsa-miR-302b (0.0033) hsa-miR-148b (0.0056) hsa-miR-302c (0.0074)
[NAME] | PKMYT1 CCNB1 CCNB2 PLK1 CDK7 CDC25C CDC25A CDC25B |  | hsa-miR-496 (2.2e-06) hsa-miR-148a (0.00023) hsa-miR-152 (0.004)
[NAME] | RAD1 DBF4 HUS1 CLSPN ATRIP [NAME] CDC7 CDC6 CCNB1 CCNB2 ORC6L CDK2 ORC5L ORC2L CDC25C CDC25A RFC5 RFC3 RFC4 RFC2 CHEK1 CHEK2 MCM10 MCM8 MCM2 MCM3 MCM4 [NAME] | * | hsa-miR-185 (2.6e-14) hsa-let-7b (1.6e-11) hsa-let-7f (4.8e-11) hsa-miR-30c (6e-10) hsa-miR-30b (3e-09) hsa-miR-128b (3.2e-08) hsa-miR-643 (9.9e-08) hsa-miR-30e-3p (0.00047) hsa-miR-186 (0.0018) hsa-miR-302b (0.0032)
REACTOME_FORMATION_OF_THE_EARLY_ELONGATION_COMPLEX | NCBP2 [NAME] GTF2H3 CDK7 POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] |  | hsa-miR-496 (1.9e-09)
REACTOME_APOPTOSIS | BCL2L1 HIST1H1D HIST1H1C HIST1H1B FADD PTK2 [NAME] DBNL LMNB1 CLSPN BID YWHAB OCLN PMAIP1 BMF PRKCD DIABLO STK24 TRAF2 BAK1 PSMD14 PSMD13 PSMD11 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 BBC3 PSMC2 AKT1 PAK2 PSMD1 PSMD2 PSMD3 PSMD4 KPNB1 PSMD8 [NAME] |  | [NAME] (2.3e-12) hsa-miR-30b (2e-09) hsa-miR-802 (1.3e-07) hsa-miR-328 (9.1e-07) hsa-miR-186 (1.1e-05) hsa-miR-555 (5.8e-05) hsa-miR-146a (0.00011) hsa-miR-152 (0.00094) hsa-miR-9 (0.0011) hsa-miR-146b (0.0016) hsa-let-7a (0.0016) hsa-let-7b (0.0044) hsa-miR-30c (0.0079)
REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | [NAME] |  | hsa-miR-367 (0.004)
REACTOME_TIE2_SIGNALING | HRAS NRAS KRAS GRB2 SHC1 PIK3R2 |  | hsa-let-7b (0.00048)
REACTOME_GAB1_SIGNALOSOME | EGFR PXN PIK3R1 |  | hsa-miR-218 (9.8e-11) hsa-miR-145 (6.3e-09)
REACTOME_DIABETES_PATHWAYS | RPL14 RPL13 RPL15 FAU GNG2 RPL11 [NAME] RPS14 [NAME] CACNB2 RPS25 RPS29 RPS6 RPS5 RPS8 RPS7 [NAME] RPL32 [NAME] RPL34 SNAP25 ETFB EXOC1 ETFA RPL26 IGF1 RPL27 IGF2 RPL29 RPL22 RPL21 SDHD PRKAR2B RPS27A RPL35A VAMP2 RPL9 ADRA2A RPL3 ADRA2C RPL5 RPL10A [NAME] IDH3A DNAJB9 ATF3 CACNA1C CACNA1A PC NDUFS4 RPS3A SUCLA2 STXBP1 RPS4X CHRM3 PKLR LEP ADCY8 [NAME] SUCLG1 PFKFB3 ALDOC PFKFB1 KLF4 ETFDH ITPR1 ITPR2 CPE BCHE RAP1A UQCRC2 IGFBP6 PLCB1 PRKCA PFKM IGFBP1 IGFBP3 |  | hsa-miR-424 (9.3e-11) hsa-miR-181c (4.3e-07) hsa-miR-218 (7.4e-06) hsa-miR-20a (8.2e-05) hsa-miR-142-5p (0.00011) hsa-miR-375 (0.0051) hsa-miR-183 (0.0054)
[NAME] | HLA-DQA2 HLA-DOA WAS HLA-DQB1 ENAH FYB VASP EVL PAK2 PAK1 |  | hsa-miR-9 (0.0091)
REACTOME_INFLUENZA_LIFE_CYCLE | RPL18 [NAME] RPL13 RPL15 RPLP2 RPL10 FAU RPL11 [NAME] RPS14 [NAME] [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 RPL41 RPL37 RPL32 [NAME] RPL26 RPL27 RPL24 RPL29 RPL22 [NAME] RPL35A RPL6 RPL9 RPL3 RPL5 RPL10A RPL7A RPL4 RPL37A RPS3 RPS3A RPS4X RPS15A RPL13A NUP54 RPL27A POLR2A POM121 |  | hsa-miR-142-5p (7.4e-13) hsa-miR-218 (5.3e-10) hsa-miR-23b (4.4e-09) hsa-miR-181c (4.5e-07) hsa-miR-376a (3e-06) hsa-miR-376b (0.00017) hsa-miR-16 (0.003) hsa-miR-181a (0.006)
REACTOME_ERK_MAPK_TARGETS | MEF2C MEF2A PPP2CB RPS6KA5 RPS6KA3 DUSP6 PPP2R1B |  | hsa-miR-145 (9.2e-23) hsa-miR-23b (6.4e-09) hsa-miR-20a (1e-05) hsa-miR-183 (4.2e-05) hsa-miR-92 (0.00014) hsa-miR-142-5p (0.00017) hsa-miR-19b (0.0027)
REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | ACACB ACSL1 |  | hsa-miR-130a (0.00078) hsa-miR-218 (0.0055)
REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS | IGF1 IGF2 KLK3 IGFBP6 IGFBP1 IGFBP3 |  | hsa-miR-19b (1.9e-13) hsa-miR-19a (0.00022)
REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | CCL28 CCL27 CCL21 CCBP2 CCL19 CCL16 CXCL12 CCL2 CX3CL1 XCL2 CCRL1 PF4 PPBP CCR3 [NAME] CXCL1 CXCL3 CXCL2 CXCL6 CXCR7 |  | hsa-miR-142-5p (8e-19) hsa-miR-23b (6.2e-13) hsa-miR-15a (0.00011) hsa-miR-101 (0.00038) hsa-miR-144 (0.00073)
REACTOME_FORMATION_OF_PLATELET_PLUG | A2M GNG2 GNG7 F8 SERPING1 GNAI1 [NAME] GNG13 GNG11 DGKB SOS1 SELP IGF1 DGKI P2RY12 GNG10 FGA ADRA2A ADRA2C EGF P2RX1 PF4 FIGF RAPGEF3 CFD VEGFC CD36 PPBP PLA2G4A TF ITPR1 ITPR2 [NAME] PDGFA MMRN1 TTN CLU ITGB1 ALB SRGN PLCG2 HABP4 RAP1A TLN1 MGLL AKT3 PRKCA PROS1 RASGRP2 SCG3 HRG PIK3R1 VWF |  | hsa-miR-130a (4.5e-07) hsa-miR-218 (6.4e-06) hsa-miR-144 (1.9e-05) hsa-miR-367 (4.7e-05) hsa-miR-301 (5.8e-05) hsa-miR-181c (7.3e-05) hsa-miR-92 (0.00016) hsa-miR-149 (0.0012) hsa-miR-15b (0.0027) hsa-miR-424 (0.0036) hsa-miR-130b (0.0059) hsa-miR-20a (0.0073) hsa-miR-20b (0.0091)
REACTOME_RNA_POLYMERASE_I_CHAIN_ELONGATION | [NAME] HIST1H3G HIST1H3H HIST1H3I UBTF H3F3A GTF2H3 CDK7 POLR1B POLR2H POLR2K | * | hsa-miR-496 (3e-35)
REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | GARS HARS FARSB FARSA CARS TARS YARS MARS VARS EPRS NARS LARS |  | hsa-miR-205 (3.7e-06)
REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN | CD36 FYN ITGB1 VWF |  | hsa-miR-29a (0.00071)
REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | RPL18 [NAME] RPL13 RPL15 RPLP2 RPL10 FAU RPL11 RPL12 HNF4G RPS18 HNF4A [NAME] RPS14 [NAME] [NAME] RPS23 RPS24 RPS9 RPS6 RPS5 RPS8 RPS7 HNF1A RPL41 RPL35 RPL37 RPL38 RPL32 [NAME] RPL26 RPL27 RPL24 RPL29 RPL23 [NAME] SLC2A2 RPS27A RPL35A RPL6 RPL9 RPL3 RPL5 RPL10A RPL7A RPL4 RPL37A PAX6 RPS3 RPS3A RPS4X PKLR RPS15A RPL13A RPL27A [NAME] | * | hsa-miR-142-5p (1.3e-59) hsa-miR-376b (5.2e-43) hsa-miR-376a (1.6e-37) hsa-miR-181c (2.7e-22) hsa-miR-23b (1.3e-14) hsa-miR-15b (4.4e-09) hsa-miR-218 (6.1e-08) hsa-miR-137 (2.2e-07) hsa-miR-29b (7.9e-06) hsa-miR-16 (1e-05) hsa-miR-20b (2.9e-05) hsa-miR-365 (0.00094) hsa-miR-20a (0.001) hsa-miR-29c (0.001) hsa-miR-23a (0.0018) hsa-miR-106b (0.0057) hsa-miR-15a (0.0067) hsa-miR-150 (0.0094)
REACTOME_AXON_GUIDANCE | HRAS MAPK1 CACNB3 PFN1 PFN2 RAC2 RAC1 ARHGEF11 NRAS GSK3B PTK2 [NAME] COL5A2 COL5A1 SEMA7A FARP2 RND1 CDK5R1 CD72 KRAS CAP1 ARTN SEMA4D YWHAB ROBO2 PLXNC1 GRB2 SPTBN2 CFL1 ERBB2 MAP2K2 COL6A3 COL1A2 COL1A1 CACNA1I CACNA1H CACNA1D CDC42 RHOC GPC1 RHOG LIMK1 CDK5 VASP TREM2 AGRN SRC EVL PAK2 PAK1 GRLF1 |  | [NAME] (0.0011)
REACTOME_REGULATION_OF_APC_ACTIVATORS_BETWEEN_G1_S_AND_EARLY_ANAPHASE | ANAPC2 ANAPC7 FBXO5 UBE2C BUB3 CCNB1 PLK1 MAD2L1 CDC20 PSMD14 PSMD13 PSMD11 PSMA6 PSMA4 PSMA3 FZR1 ANAPC11 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] | * | hsa-miR-802 (1.6e-43) hsa-miR-186 (8.8e-13) hsa-miR-146b (1.3e-08) hsa-miR-146a (2.4e-06) hsa-miR-30b (2.3e-05) hsa-miR-620 (2.9e-05) hsa-miR-603 (0.0016) hsa-miR-515-5p (0.0024) hsa-miR-30d (0.0025) hsa-miR-765 (0.0063)
REACTOME_MITOTIC_M_M_G1_PHASES | PPP2R5D RCC2 ZWINT AHCTF1 NDC80 KNTC1 [NAME] MAD1L1 E2F3 KIF2C NDE1 AURKB FBXO5 SEH1L DSN1 [NAME] RAD21 SPC25 [NAME] ORC1L NUF2 CDC6 BUB1 BUB3 ORC6L PLK1 SEC13 NUP85 ORC5L NUP98 ORC2L MAD2L1 CDC20 PMF1 CDT1 PSMD14 PSMD13 PSMD11 SGOL2 SGOL1 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 CKAP5 CASC5 PSMC4 PSMC2 MCM8 PSMD1 PSMD2 PSMD3 PSMD4 PSMD8 MCM2 MCM3 MCM4 MCM6 [NAME] CENPA CENPO CENPN CENPM CENPL CENPP KIF18A CENPF CENPE CENPK CENPI | * | hsa-miR-186 (4.1e-38) hsa-miR-328 (7.5e-34) hsa-miR-146b (9.1e-22) hsa-miR-30b (8.4e-16) hsa-miR-125b (2.4e-15) hsa-miR-148a (2.1e-13) hsa-miR-767-3p (1.3e-10) hsa-miR-555 (2.5e-10) hsa-miR-146a (1.6e-09) hsa-miR-802 (2e-09) hsa-miR-515-5p (4.4e-07) hsa-miR-34a (6.8e-07) hsa-miR-148b (1.4e-06) hsa-miR-30d (4.8e-06) hsa-miR-185 (9e-06) hsa-miR-643 (9.6e-06) hsa-miR-152 (2.5e-05) hsa-miR-200a (0.0001) hsa-miR-765 (0.00012) hsa-miR-620 (0.00016) hsa-miR-124 (0.0022) hsa-miR-122a (0.003)
REACTOME_RNA_POLYMERASE_I_PROMOTER_ESCAPE | UBTF ERCC3 ERCC2 RRN3 GTF2H4 GTF2H3 CDK7 POLR1A POLR1B POLR2H POLR2K |  | hsa-miR-496 (0.0073)
REACTOME_SIGNALING_BY_TGF_BETA | TGFBR2 [NAME] |  | hsa-miR-19b (5.3e-06)
[NAME] | RAE1 SEH1L NUP188 TPR NUP155 RANGAP1 NUP205 NUP214 NUP210 XPO1 NUP85 NUP98 NUP93 NUP50 NUP62 NUPL1 | * | hsa-miR-142-3p (3.1e-09) hsa-miR-185 (3e-08) hsa-miR-514 (1.1e-07) hsa-miR-125a (5e-07) hsa-miR-30b (0.00053) hsa-miR-129-3p (0.0012) hsa-miR-30c (0.0027)
REACTOME_PYRUVATE_METABOLISM | LDHB PDK4 |  | hsa-miR-15a (0.0083)
REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | RAC2 RAC1 ARHGEF11 RND1 SEMA4D ERBB2 CDC42 RHOC RHOG LIMK1 |  | hsa-miR-206 (0.0066)
REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION | FES SEMA3A FYN |  | hsa-miR-145 (4.1e-11) hsa-miR-92 (1.6e-05) hsa-miR-96 (0.0068)
REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | GYG2 PGM1 PHKB PYGM PYGL CALM1 |  | hsa-miR-770-5p (6.8e-05)
[NAME] | AP2S1 CACNG4 AP2M1 AP2B1 AP2A2 AP2A1 PICK1 MDM2 CAMK2A MYO6 NSF |  | [NAME] (1.8e-05)
REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION | TAF10 TAF13 TAF12 SSRP1 NCBP2 NCBP1 SUPT16H CTDP1 TH1L ERCC3 ERCC2 RDBP GTF2H4 GTF2H3 SUPT4H1 TCEB2 TCEB3 [NAME] TAF4 TAF5 WHSC2 GTF2A1 NFX1 CDK7 CPSF3 CPSF2 CPSF1 U2AF2 RBM8A SFRS9 SFRS2 ELL RNGTT POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] PAPOLA CSTF3 CSTF2 RNPS1 CSTF1 | * | hsa-miR-496 (8.2e-11) hsa-let-7f (1.1e-09) hsa-miR-148a (3.5e-09) hsa-miR-30b (1e-06) hsa-miR-132 (1.2e-06) hsa-miR-152 (1.3e-05) hsa-miR-34a (1.4e-05) hsa-miR-1 (5.6e-05) hsa-miR-148b (8.1e-05) hsa-miR-93 (0.0083) hsa-miR-320 (0.0087) hsa-miR-155 (0.0092)
REACTOME_DEADENYLATION_OF_MRNA | PABPC1 CNOT10 RQCD1 CNOT3 CNOT6 PARN EIF4G1 |  | hsa-miR-148a (0.0018) hsa-miR-302c (0.003) hsa-miR-186 (0.0072)
REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS | ARF1 AP2S1 AP2M1 AP2B1 AP2A2 PACS1 AP1S3 AP1S1 AP1G1 ATP6V1H AP1M1 AP1M2 AP1B1 | * | [NAME] (3.2e-09) hsa-miR-299-3p (6.1e-09) hsa-miR-206 (1.3e-08) hsa-miR-1 (9.1e-07) hsa-miR-152 (1.9e-05) hsa-let-7f (4.5e-05) hsa-let-7b (0.00031) hsa-miR-148b (0.00076) hsa-miR-204 (0.0086) hsa-let-7a (0.0093)
REACTOME_NEURORANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL | HRAS MAPK1 GNGT1 [NAME] CAMK2A GNG5 GNB2 GNB1 GNB3 RPS6KA1 [NAME] [NAME] CAMKK1 MYO6 PLCB3 PLCB2 NSF |  | hsa-miR-152 (0.0018)
REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES | MEF2C MEF2A JUN PPP2CB RPS6KA5 RPS6KA3 DUSP6 ATF1 PPP2R1B FOS |  | hsa-miR-145 (5.9e-30) hsa-miR-181c (9.1e-11) hsa-miR-92 (4.6e-06) hsa-miR-20a (4.1e-05) hsa-miR-142-5p (8.3e-05) hsa-miR-183 (0.00011) hsa-miR-543 (0.00072) hsa-miR-19b (0.00076) hsa-miR-181a (0.0026) hsa-miR-23b (0.0076)
REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | [NAME] PMAIP1 BMF BBC3 AKT1 |  | hsa-miR-148b (0.00059)
REACTOME_TRIACYLGLYCERIDE_BIOSYNTHESIS | GPD1 [NAME] PPAP2A PPAP2B |  | hsa-miR-218 (4.8e-47) hsa-miR-149 (2.7e-16) hsa-miR-16 (0.0036) hsa-miR-27b (0.0048) hsa-miR-29a (0.0076) hsa-miR-15a (0.0077)
REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | FGF7 FGF9 FGF2 IRS2 IRS1 KL FGF10 FGFR1 PIK3R1 |  | hsa-miR-145 (1.1e-22) hsa-miR-181a (2.3e-09) hsa-miR-183 (1.8e-05) hsa-miR-181b (4.4e-05) hsa-miR-16 (6e-05) hsa-miR-181c (0.00059) hsa-miR-424 (0.0012) hsa-miR-33 (0.0012) hsa-miR-92 (0.0018)
REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | SNAP25 VAMP2 DDC STXBP1 SYN2 |  | hsa-miR-335 (1.5e-13) hsa-miR-92 (1.5e-10) hsa-miR-367 (3.9e-10) hsa-miR-25 (1.3e-08) hsa-miR-32 (5.5e-05) hsa-miR-153 (0.0001) hsa-miR-218 (0.00099)
REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING | [NAME] GNG13 GNG11 GRIK1 GRIK2 NCALD CALM1 PLCB1 |  | hsa-miR-19b (2.9e-08) hsa-miR-181c (3.2e-05) hsa-miR-181a (0.00087) hsa-miR-137 (0.01)
REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE | ARHGEF16 ARHGEF11 FGD3 [NAME] PSENEN MAGED1 ARHGEF2 VAV2 APH1A TRIO PSEN1 PSEN2 AATF ECT2 |  | hsa-miR-1 (0.00024)
REACTOME_SHCMEDIATED_CASCADE | [NAME] FGF9 FGF1 FGF2 SOS1 FGF10 FGFR1 |  | hsa-miR-15a (0.00075) hsa-miR-183 (0.0029)
REACTOME_STABILIZATION_OF_P53 | MDM2 RFWD2 PSMD14 PSMD13 PSMD11 PSMA6 PSMA4 PSMA3 PSMA7 PSMB4 PSMB3 PSMB2 PSMC4 PSMC2 PSMD1 PSMD2 PSMD3 PSMD4 [NAME] | * | hsa-miR-802 (5.8e-41) hsa-miR-146a (1.3e-13) hsa-miR-765 (1.7e-10) hsa-miR-186 (3e-09) hsa-miR-146b (9.6e-07) hsa-miR-620 (1.4e-06) hsa-miR-555 (0.0014) hsa-miR-515-5p (0.0029) hsa-miR-30e-5p (0.0056) hsa-miR-30c (0.0078)
REACTOME_HIV_LIFE_CYCLE | RAE1 [NAME] TAF10 TAF13 TAF12 FEN1 SSRP1 NCBP2 NCBP1 CCR5 BANF1 SUPT16H SEH1L CTDP1 TH1L PPIA NUP188 CXCR4 RANBP1 TPR ERCC2 [NAME] GTF2H4 GTF2H3 NUP205 NUP214 NUP210 TCEB2 TCEB3 [NAME] GTF2E1 TAF1 TAF4 TAF5 WHSC2 GTF2A1 NUP85 [NAME] NUP62 RNGTT POLR2H POLR2G POLR2K POLR2J POLR2I [NAME] | * | hsa-miR-125b (4.5e-18) hsa-let-7g (1.1e-07) hsa-miR-302c (7.1e-07) hsa-let-7f (1.2e-06) hsa-miR-204 (4.5e-06) hsa-miR-320 (2.3e-05) hsa-miR-129-3p (0.00018) hsa-miR-148a (0.00025) hsa-miR-30c (0.00025) hsa-miR-153 (0.00027) hsa-let-7b (0.0005) hsa-miR-132 (0.00072) hsa-miR-34a (0.00075) hsa-miR-200a (0.0016) hsa-miR-299-3p (0.0026) hsa-miR-302a (0.0041) hsa-miR-206 (0.0048) hsa-miR-152 (0.0078)