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Journal of interesting things
OCTOBER | PDF DOWNLOADS
DOI | Title | Volume | Issue | Page | Type | Page Views
[NAME] |  |  |  |  |  | 153383
10.1038/ng1005-1027 | Stem cells, asymmetric division and cancer | 37 | 10 | 1027-1028 | N&V | 2054
10.1038/ng1650 | Second-generation shRNA libraries covering the mouse and human genomes | aop | current | - | Technical Report | 1528
10.1038/ng1631 | Genomic alterations in cultured human embryonic stem cells | 37 | 10 | 1099-1103 | Letter | 1514
10.1038/ng1634 | The melanocyte differentiation program predisposes to metastasis after neoplastic transformation | 37 | 10 | 1047-1054 | Letter | 1213
10.1038/ng1651 | Probing tumor phenotypes using stable and regulated synthetic microRNA precursors | aop | current | - | Technical Report | 1139
10.1038/ng1632 | Induction of tumor growth by altered stem-cell asymmetric division in <i>Drosophila melanogaster</i> | 37 | 10 | 1125-1129 | Letter | 1025
10.1038/ng1655 | Genetic variation in selenoprotein S influences inflammatory response | 37 | 11 | 1234-1241 | Article | 953
10.1038/ng1005-1026 | Metastatic potential as a heritable trait | 37 | 10 | 1026-1027 | N&V | 902
10.1038/ng1640 | The synthetic genetic interaction spectrum of essential genes | 37 | 10 | 1147-1152 | Letter | 851
10.1038/ng1646 | A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility | 37 | 10 | 1113-1118 | Letter | 837
SEPTEMBER | PDF DOWNLOADS
DOI | Title | Volume | Issue | Page | Type | Page Views
[NAME] |  |  |  |  |  | 143559
10.1038/ng1631 | Genomic alterations in cultured human embryonic stem cells | 37 | 10 | 1099-1103 | Letter | 3360
10.1038/ng0905-917 | Defining epigenetic states through chromatin and RNA | 37 | 9 | 917-918 | Meeting Review | 1840
10.1038/ng1632 | Induction of tumor growth by altered stem-cell asymmetric division in <i>Drosophila melanogaster</i> | 37 | 10 | 1125-1129 | Letter | 1385
10.1038/ng0905-921 | Unraveling the Fanconi anemia&ndash;DNA repair connection | 37 | 9 | 921-922 | N&V | 1310
10.1038/ng1630 | Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs | 37 | 9 | 991-996 | Letter | 1286
10.1038/ng1634 | The melanocyte differentiation program predisposes to metastasis after neoplastic transformation | 37 | 10 | 1047-1054 | Article | 1248
10.1038/ng1616 | Contributions of low molecule number and chromosomal positioning to stochastic gene expression | 37 | 9 | 937-944 | Article | 1206
10.1038/ng1618 | Intragenic tandem repeats generate functional variability | 37 | 9 | 986-990 | Letter | 1180
10.1038/ng1005-1027 | Stem cells, asymmetric division and cancer | 37 | 10 | 1027-1028 | N&V | 925
10.1038/ng0495-424 | The apolipoprotein(<i>a</i>) gene is regulated by sex hormones and acute&ndash;phase inducers in YAC transgenic mice | 9 | 4 | 424-431 | N&V | 833
AUGUST | PDF DOWNLOADS
DOI | Title | Volume | Issue | Page | Type | Page Views
[NAME] |  |  |  |  |  | 116895
10.1038/ng0397-269 | Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia | 15 | 3 | 269-272 | N&V | 3851
10.1038/ng1598 | Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells | 37 | 8 | 853-862 | Article | 1721
10.1038/ng1611 | Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation | 37 | 8 | 906-910 | Letter | 1645
10.1038/ng1596 | Distinct epigenetic changes in the stromal cells of breast cancers | 37 | 8 | 899-905 | Letter | 1527
10.1038/ng1602 | Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome | 37 | 8 | 809-819 | Article | 1485
10.1038/ng1604 | Variants of <i>ENPP1</i> are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes | 37 | 8 | 863-867 | Letter | 1157
10.1038/ng1610 | Nova regulates brain-specific splicing to shape the synapse | 37 | 8 | 844-852 | Article | 1010
10.1038/ng0805-796 | Splicing on the brain | 37 | 8 | 796-797 | N&V | 901
10.1038/ng0805-794 | Pharmacogenetics goes 3D | 37 | 8 | 794-795 | N&V | 874
10.1038/ng1607 | Demonstrating stratification in a European American population | 37 | 8 | 868-872 | Letter | 716
JULY | PDF DOWNLOADS
DOI | Title | Volume | Issue | Page | Type | Page Views
[NAME] |  |  |  |  |  | 123175
10.1038/ng1090 | Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease | 33 | 3s | 228-237 | Review | 3561
10.1038/ng1590 | Identification of hundreds of conserved and nonconserved human microRNAs | 37 | 7 | 766-770 | Letter | 2669
10.1038/ng1589 | An integrative genomics approach to infer causal associations between gene expression and disease | 37 | 7 | 710-717 | Article | 1966
10.1038/ng0705-653 | Pause for postdocs | 37 | 7 | 653-653 | N&V | 1586
10.1038/ng1572 | Temporal dissection of p53 function <i>in vitro</i> and <i>in vivo</i> | 37 | 7 | 718-726 | Article | 1535
10.1038/ng1562 | Fine-scale structural variation of the human genome | 37 | 7 | 727-732 | Letter | 1414
10.1038/ng0705-659 | RNA polymerase IV and transcriptional silencing | 37 | 7 | 659-660 | N&V | 1285
10.1038/ng1593 | Priorities and standards in pharmacogenetic research | 37 | 7 | 671-681 | Perspective | 1152
10.1038/ng1598 | Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells | 37 | 8 | 853-862 | Article | 1098
10.1038/ng0705-660 | Vive la difference! | 37 | 7 | 660-661 | N&V | 1090
[NAME] | PDF DOWNLOADS
DOI | Title | Volume | Issue | Page | Type | Page Views
[NAME] |  |  |  |  |  | 124463
10.1038/ng1571 | A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer | 37 | 6 | 590-592 | Brief Comms | 2512
10.1038/ng1556 | Epigenetic status of human embryonic stem cells | 37 | 6 | 585-587 | Brief Comms | 2496
10.1038/ng1578 | Mining for regulatory programs in the cancer transcriptome | 37 | 6 | 579-583 | Analysis | 1481
10.1038/ng1559 | Mapping of genetic and epigenetic regulatory networks using microarrays | 37 | 6s | S18-S24 | Perspective | 1405
10.1038/ng1590 | Identification of hundreds of conserved and nonconserved human microRNAs | 37 | 7 | 766-770 | Letter | 1357
10.1038/ng1565 | Human recombination hot spots hidden in regions of strong marker association | 37 | 6 | 601-606 | Letter | 1275
10.1038/ng1575 | Alternative splicing and gene duplication are inversely correlated evolutionary mechanisms | 37 | 6 | 588-589 | Brief Comms | 1220
10.1038/ng1560 | Cell microarrays and RNA interference chip away at gene function | 37 | 6s | S25-S30 | Perspective | 1211
10.1038/ng0605-557 | Beyond genomics | 37 | 6 | 557-557 | N&V | 1107
10.1038/ng1561 | From signatures to models: understanding cancer using microarrays | 37 | 6s | S38-S45 | Perspective | 1088
MAY | PDF DOWNLOADS
DOI | Title | Volume | Issue | Page | Type | Page Views
[NAME] |  |  |  |  |  | 119865
10.1038/ng1536 | Combinatorial microRNA target predictions | 37 | 5 | 495-500 | Letter | 2019
10.1038/ng1547 | A genome-wide scalable SNP genotyping assay using microarray technology | 37 | 5 | 549-554 | Technical Report | 1824
10.1038/ng1545 | Epistasis analysis with global transcriptional phenotypes | 37 | 5 | 471-477 | Article | 1692
10.1038/ng1543 | A gene expression map of <i>Arabidopsis thaliana</i> development | 37 | 5 | 501-506 | Letter | 1268
10.1038/ng0505-457 | Universal epistasis analysis | 37 | 5 | 457-458 | N&V | 1251
10.1038/ng1556 | Epigenetic status of human embryonic stem cells | 37 | 6 | 585-587 | Brief Comms | 1164
10.1038/ng0505-460 | Epigenetics of hypertension in pregnancy | 37 | 5 | 460-461 | N&V | 1037
10.1038/ng1552 | Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways | 37 | 5 | 537-543 | Letter | 1010
10.1038/ng1557 | A functional SNP in <i>CILP</i>, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease | 37 | 6 | 607-612 | Letter | 961
10.1038/ng1540 | A functional variant in <i>FCRL3</i>, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities | 37 | 5 | 478-485 | Article | 943
APRIL | PDF DOWNLOADS
DOI | Title | Volume | Issue | Page | Type | Page Views
[NAME] |  |  |  |  |  | 117441
10.1038/ng1537 | Genome-wide strategies for detecting multiple loci that influence complex diseases | 37 | 4 | 413-417 | Letter | 2241
10.1038/ng1531 | Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer | 37 | 4 | 391-400 | Article | 1755
10.1038/ng1536 | Combinatorial microRNA target predictions | 37 | 5 | 495-500 | Letter | 1366
10.1038/ng1532 | Reverse engineering of regulatory networks in human B cells | 37 | 4 | 382-390 | Article | 1355
10.1038/ng0405-331 | A manually curated functional annotation of the human X chromosome | 37 | 4 | 331-332 | N&V | 995
10.1038/ng1544 | <i>MHC2TA</i> is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction | 37 | 5 | 486-494 | Article | 950
10.1038/ng1534 | Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons | 37 | 4 | 349-350 | Brief Comms | 946
10.1038/ng1541 | Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family | 37 | 5 | 514-519 | Letter | 865
10.1038/ng0405-343 | The X chromosome: not just her brother's keeper | 37 | 4 | 343-345 | N&V | 787
10.1038/ng0405-333 | Frequency of new copy number variation in humans | 37 | 4 | 333-334 | N&V | 731
[NAME] | PDF DOWNLOADS
DOI | Title | Volume | Issue | Page | Type | Page Views
[NAME] |  |  |  |  |  | 136083
10.1038/ng1505 | MAGIC, an <i>in vivo</i> genetic method for the rapid construction of recombinant DNA molecules | 37 | 3 | 311-319 | Technical Report | 1986
10.1038/ng1522 | Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease | 37 | 3 | 243-253 | Article | 1900
10.1038/ng1497 | Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics' | 37 | 3 | 225-232 | Article | 1855
10.1038/ng0305-212 | SWItching off methylated DNA | 37 | 3 | 212-213 | N&V | 1813
10.1038/ng1531 | Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer | 37 | 4 | 391-400 | Article | 1596
10.1038/ng0305-211 | Comparative epigenomics of leukemia | 37 | 3 | 211-212 | N&V | 1477
10.1038/ng1518 | Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function | 37 | 3 | 233-242 | Article | 1421
10.1038/ng0305-209 | Mapping expression in randomized rodent genomes | 37 | 3 | 209-210 | N&V | 1404
10.1038/ng1516 | Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing | 37 | 3 | 254-264 | Article | 1382
10.1038/ng1521 | Global assessment of promoter methylation in a mouse model of cancer identifies <i>ID4</i> as a putative tumor-suppressor gene in human leukemia | 37 | 3 | 265-274 | Article | 1332
FEBRUARY | PDF DOWNLOADS
DOI | Title | Volume | Issue | Page | Type | Page Views
[NAME] |  |  |  |  |  | 108099
10.1038/ng0205-116 | Telomere-binding factors and general DNA repair | 37 | 2 | 116-118 | N&V | 1556
10.1038/ng1506 | Human telomeric protein [NAME] associates with genomic double-strand breaks as an early response to DNA damage | 37 | 2 | 193-197 | Letter | 1353
10.1038/ng1508 | A common inversion under selection in Europeans | 37 | 2 | 129-137 | Article | 1308
10.1038/ng0205-109 | Genewindow: an interactive tool for visualization of genomic variation | 37 | 2 | 109-110 | N&V | 1282
10.1038/ng1516 | Brahma links the SWI/SNF chromatin-remodeling complex with MeCP2-dependent transcriptional silencing | 37 | 3 | 254-264 | Article | 1134
10.1038/ng1502 | An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas | 37 | 2 | 182-186 | Letter | 1115
10.1038/ng1504 | System-level identification of transcriptional circuits underlying mammalian circadian clocks | 37 | 2 | 187-192 | Letter | 1097
10.1038/ng0205-107 | Human evolution has its Dobzhansky moment | 37 | 2 | 107-107 | N&V | 1049
10.1038/ng1497 | Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics' | 37 | 3 | 225-232 | Article | 1039
10.1038/ng1522 | Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease | 37 | 3 | 243-253 | Article | 1031
JANUARY | PDF DOWNLOADS
DOI | Title | Volume | Issue | Page | Type | Page Views
[NAME] |  |  |  |  |  | 75889
10.1038/ng1494 | Dysregulation of the TSC-mTOR pathway in human disease | 37 | 1 | 19-24 | Review | 1266
10.1038/ng1496 | An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis | 37 | 2 | 138-144 | Article | 1109
10.1038/ng0105-10 | Is [NAME] syndrome a loss-of-imprinting disorder? | 37 | 1 | 38666 | N&V | 972
10.1038/ng1502 | An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas | 37 | 2 | 182-186 | Letter | 800
10.1038/ng1508 | A common inversion under selection in Europeans | 37 | 2 | 129-137 | Article | 779
10.1038/ng0105-13 | A global view of epistasis | 37 | 1 | 13-14 | N&V | 731
10.1038/ng0105-7 | Cross-species comparisons of cancer signaling | 37 | 1 | 38571 | N&V | 712
10.1038/ng1504 | System-level identification of transcriptional circuits underlying mammalian circadian clocks | 37 | 2 | 187-192 | Letter | 693
10.1038/ng1473 | Rapid analysis of the DNA-binding specificities of transcription factors with DNA microarrays | 36 | 12 | 1331-1339 | Technical Report | 671
10.1038/ng1165 | Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data | 34 | 2 | 166-176 | Article | 626