Spreadsheet: 2128ac9d-a239-496c-9286-edf2c8d8bf55
Sheet: Sheet1

ID | Metabolite Name | T2DM vs FH-+T2DM vs NGT | T2DM vs FH-+T2DM vs IGT | T2DM vs NGT+T2DM vs IGT | T2DM vs FH-+T2DM vs NGT+T2DM vs IGT
[NAME]] | 2-Oxoglutarate | 0 | 0 | 0 | 0
2oxoadp[m] | 2-Oxoadipate | 0 | 0 | 0 | 0
nad[m] | Nicotinamide adenine dinucleotide | 0 | 0 | 0 | 0
nadh[m] | Nicotinamide adenine dinucleotide - reduced | 0 | 0 | 0 | 0
pail34p_hs[c] | phosphatidylinositol-3,4-bisphosphate (Homo sapiens) | 0 | 1 | 0 | 0
h[m] | H+ | 0 | 0 | 0 | 0
glutcoa[m] | Glutaryl-CoA | 0 | 0 | 0 | 0
coa[m] | Coenzyme A | 0 | 0 | 0 | 0
focytC[m] | Ferrocytochrome C | 1 | 1 | 1 | 1
ficytC[m] | Ferricytochrome c | 1 | 1 | 1 | 1
pail35p_hs[c] | phosphatidylinositol-3,5-bisphosphate (Homo sapiens) | 0 | 0 | 0 | 0
pail3p_hs[c] | 1-Phosphatidyl-1D-myo-inositol 3-phosphate (Homo sapiens) | 0 | 0 | 0 | 0
2mop[m] | 2-Methyl-3-oxopropanoate | 0 | 0 | 0 | 0
msa[m] | Malonate semialdehyde | 0 | 0 | 0 | 0
g6p[c] | D-Glucose 6-phosphate | 0 | 0 | 0 | 0
succoa[m] | Succinyl-CoA | 1 | 0 | 0 | 0
dhbpt[c] | 6,7-Dihydrobiopterin | 0 | 1 | 0 | 0
f6p[c] | D-Fructose 6-phosphate | 0 | 1 | 0 | 0
dd2coa[m] | [NAME] | 0 | 0 | 0 | 0
dd3coa[m] | 3-dodecenoyl CoA | 0 | 0 | 0 | 0
mal-L[c] | L-Malate | 0 | 0 | 0 | 0
pail5p_hs[c] | 1-Phosphatidyl-1D-myo-inositol 5-phosphate (Homo sapiens) | 0 | 0 | 0 | 0
paf_hs[c] | 1-alkyl 2-acteylglycerol 3-phosphocholine (homo sapiens) | 0 | 0 | 0 | 0
ak2lgchol_hs[c] | 1-alkyl 2-lysoglycerol 3-phosphocholine | 0 | 0 | 0 | 0
[NAME]] | L-Lactate | 0 | 0 | 0 | 0
pail_hs[c] | phosphatidylinositol (homo sapiens) | 0 | 1 | 0 | 0
fum[m] | Fumarate | 0 | 0 | 0 | 0
glyc[c] | Glycerol | 0 | 0 | 0 | 0
23dpg[c] | 2,3-Disphospho-D-glycerate | 0 | 0 | 0 | 0
mi14p[c] | 1D-myo-Inositol 1,4-bisphosphate | 0 | 1 | 0 | 0
3mb2coa[m] | 3-Methylbut-2-enoyl-CoA | 0 | 0 | 0 | 0
2pg[c] | D-Glycerate 2-phosphate | 0 | 0 | 0 | 0
acac[c] | Acetoacetate | 1 | 0 | 0 | 0
fe2[m] | Fe2+ | 0 | 0 | 0 | 0
pheme[m] | Protoheme | 0 | 0 | 0 | 0
ala-B[m] | beta-Alanine | 0 | 0 | 0 | 0
creat[m] | [NAME] | 0 | 0 | 0 | 0
pcreat[m] | Phosphocreatine | 0 | 0 | 0 | 0
[NAME]] | L-Glutamate | 0 | 0 | 0 | 0
ggn[c] | primed glycogenin (glycogenin-8[1,4-Glc]) | 0 | 0 | 0 | 0
[NAME] | L-erythro-4-Hydroxyglutamate | 0 | 0 | 0 | 0
f26bp[c] | D-Fructose 2,6-bisphosphate | 0 | 0 | 0 | 0
pail345p_hs[c] | phosphatidylinositol-3,4,5-trisphosphate (Homo sapiens) | 0 | 1 | 0 | 0
fad[m] | Flavin adenine dinucleotide oxidized | 0 | 0 | 0 | 0
fadh2[m] | Flavin adenine dinucleotide reduced | 0 | 0 | 0 | 0
q10[m] | Ubiquinone-10 | 1 | 0 | 0 | 0
q10h2[m] | Ubiquinol-10 | 1 | 0 | 0 | 0
co2[m] | CO2 | 0 | 0 | 0 | 0
pi[m] | Phosphate | 0 | 0 | 0 | 0
pyr[c] | Pyruvate | 0 | 0 | 0 | 0
3aib[m] | [NAME] | 0 | 0 | 0 | 0
4abut[m] | 4-Aminobutanoate | 0 | 0 | 0 | 0
btn[e] | Biotin | 0 | 0 | 0 | 0
atp[c] | ATP | 1 | 0 | 0 | 0
adp[c] | ADP | 1 | 0 | 0 | 0
[NAME]] | L-Lactate | 0 | 0 | 0 | 0
m2emgacpail_hs[r] | (dimannosyl),(phosphoethanolaminyl)-mannosyl-glucosylaminyl-acylphosphatidylinositol (H6) | 0 | 0 | 0 | 0
m3gacpail_hs[r] | trimannosyl-glucosaminyl-acylphosphatidylinositol (H4) | 0 | 0 | 0 | 0
2dp6mep[m] | 2-Decaprenyl-6-methoxyphenol | 0 | 0 | 0 | 0
2dp6mobq[m] | 2-Decaprenyl-6-methoxy-1,4-benzoquinone | 0 | 0 | 0 | 0
35cgmp[c] | 3',5'-Cyclic GMP | 0 | 0 | 1 | 0
Tyr-ggn[c] | Tyr-194 of apo-glycogenin protein (primer for glycogen synthesis) | 0 | 0 | 0 | 0
meoh[c] | Methanol | 0 | 0 | 0 | 0
antipyrene[c] | [NAME] | 0 | 0 | 1 | 0
dmantipyrine[c] | demethylated antipyrine | 0 | 0 | 1 | 0
ksii_core4_pre1[g] | keratan sulfate II biosynthesis, precursor 1 | 0 | 0 | 1 | 0
[NAME]] | keratan sulfate II biosynthesis, precursor 1 | 0 | 0 | 1 | 0
pail4p_hs[c] | 1-Phosphatidyl-1D-myo-inositol 4-phosphate (Homo sapiens) | 0 | 0 | 1 | 0
[NAME]] | 7-Dehydrodesmosterol | 0 | 0 | 0 | 0
7dhchsterol[r] | 7-Dehydrocholesterol | 0 | 0 | 0 | 0
dutp[c] | dUTP | 0 | 0 | 0 | 0
dttp[c] | dTTP | 0 | 0 | 0 | 0
didp[c] | dIDP | 0 | 0 | 0 | 0
didp[n] | dIDP | 0 | 0 | 0 | 0
ditp[n] | dITP | 0 | 0 | 0 | 0
dtdp[n] | dTDP | 0 | 0 | 0 | 0
dttp[n] | dTTP | 0 | 0 | 0 | 0
dudp[n] | dUDP | 0 | 0 | 0 | 0
idp[c] | IDP | 0 | 0 | 0 | 0
idp[n] | IDP | 0 | 0 | 0 | 0
itp[n] | ITP | 0 | 0 | 0 | 0
ksi_pre14[g] | keratan sulfate I biosynthesis, precursor 14 | 0 | 0 | 1 | 0
ksi_pre17[g] | keratan sulfate I biosynthesis, precursor 17 | 0 | 0 | 1 | 0
ksi_pre20[g] | keratan sulfate I biosynthesis, precursor 20 | 0 | 0 | 1 | 0
ksi_pre23[g] | keratan sulfate I biosynthesis, precursor 23 | 0 | 0 | 1 | 0
ksi_pre26[g] | keratan sulfate I biosynthesis, precursor 26 | 0 | 0 | 1 | 0
ksi_pre29[g] | keratan sulfate I biosynthesis, precursor 29 | 0 | 0 | 1 | 0
ksi_pre32[g] | keratan sulfate I biosynthesis, precursor 32 | 0 | 0 | 1 | 0
ksi_pre35[g] | keratan sulfate I biosynthesis, precursor 35 | 0 | 0 | 1 | 0
ksii_core4_pre6[g] | keratan sulfate II biosynthesis, precursor 6 | 0 | 0 | 1 | 0
ksii_core4_pre9[g] | keratan sulfate II biosynthesis, precursor 9 | 0 | 0 | 1 | 0
ksii_core2_pre6[g] | keratan sulfate II biosynthesis, precursor 6 | 0 | 0 | 1 | 0
ksii_core2_pre9[g] | keratan sulfate II biosynthesis, precursor 9 | 0 | 0 | 1 | 0
ksi_pre5[g] | keratan sulfate I biosynthesis, precursor 5 | 0 | 0 | 1 | 0
[NAME] | keratan sulfate I biosynthesis, precursor 8 | 0 | 0 | 1 | 0
[NAME] | keratan sulfate I biosynthesis, precursor 11 | 0 | 0 | 1 | 0
5forthf[c] | 5-Formiminotetrahydrofolate | 0 | 0 | 0 | 0
forglu[c] | N-Formimidoyl-L-glutamate | 0 | 0 | 0 | 0
ala-D[c] | D-Alanine | 0 | 0 | 0 | 0
strch1[e] | starch, structure 1 (1,6-{7[1,4-Glc], 4[1,4-Glc]}) | 0 | 0 | 0 | 0
glygn2[e] | glycogen, structure 2 (glycogenin-1,6-{7[1,4-Glc], 4[1,4-Glc]}) | 0 | 0 | 0 | 0
n3m2masn[g] | ((N-acetyl-D-glucosaminyl)3-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein) | 0 | 0 | 0 | 0
estradiol[c] | [NAME] | 0 | 0 | 1 | 0
m2mn[c] | (alpha-D-mannosyl)2-beta-D-mannosyl-N-acetylglucosamine | 0 | 0 | 0 | 0
mn[c] | beta-1,4-mannose-N-acetylglucosamine | 0 | 0 | 0 | 0
cdpchol[c] | CDPcholine | 0 | 0 | 0 | 0
nmn[c] | NMN | 0 | 0 | 0 | 0
glucys[c] | gamma-L-Glutamyl-L-cysteine | 0 | 0 | 0 | 0
dhdascb[e] | Dehydroascorbate | 0 | 0 | 0 | 0
hmbil[c] | Hydroxymethylbilane | 0 | 0 | 0 | 0
camp[c] | cAMP | 0 | 0 | 0 | 0
ksi_pre18[g] | keratan sulfate I biosynthesis, precursor 18 | 0 | 0 | 1 | 0
ksi_pre21[g] | keratan sulfate I biosynthesis, precursor 21 | 0 | 0 | 1 | 0
ksi_pre24[g] | keratan sulfate I biosynthesis, precursor 24 | 0 | 0 | 1 | 0
[NAME]] | keratan sulfate I biosynthesis, precursor 27 | 0 | 0 | 1 | 0
ksi_pre30[g] | keratan sulfate I biosynthesis, precursor 30 | 0 | 0 | 1 | 0
ksi_pre33[g] | keratan sulfate I biosynthesis, precursor 33 | 0 | 0 | 1 | 0
ksii_core4_pre3[g] | keratan sulfate II biosynthesis, precursor 3 | 0 | 0 | 1 | 0
ksii_core4_pre4[g] | keratan sulfate II biosynthesis, precursor 4 | 0 | 0 | 1 | 0
ksii_core4_pre7[g] | keratan sulfate II biosynthesis, precursor 7 | 0 | 0 | 1 | 0
ksii_core2_pre2[g] | keratan sulfate II biosynthesis, precursor 2 | 0 | 0 | 1 | 0
ksii_core2_pre3[g] | keratan sulfate II biosynthesis, precursor 3 | 0 | 0 | 1 | 0
ksii_core2_pre4[g] | keratan sulfate II biosynthesis, precursor 4 | 0 | 0 | 1 | 0
ksii_core2_pre7[g] | keratan sulfate II biosynthesis, precursor 7 | 0 | 0 | 1 | 0
ksi_pre2[g] | keratan sulfate I biosynthesis, precursor 2 | 0 | 0 | 1 | 0
ksi_pre3[g] | keratan sulfate I biosynthesis, precursor 3 | 0 | 0 | 1 | 0
ksi_pre6[g] | keratan sulfate I biosynthesis, precursor 6 | 0 | 0 | 1 | 0
ksi_pre9[g] | keratan sulfate I biosynthesis, precursor 9 | 0 | 0 | 1 | 0
ksi_pre12[g] | keratan sulfate I biosynthesis, precursor 12 | 0 | 0 | 1 | 0
ksi_pre15[g] | keratan sulfate I biosynthesis, precursor 15 | 0 | 0 | 1 | 0
core2[g] | Core 2 | 0 | 0 | 0 | 0
pcreat[c] | Phosphocreatine | 0 | 0 | 0 | 0
utp[n] | UTP | 0 | 0 | 0 | 0
udp[n] | UDP | 0 | 0 | 0 | 0
ps_hs[m] | phosphatidylserine (homo sapiens) | 0 | 0 | 0 | 0
l2fn2m2masn[g] | {[galactosyl-(1,4)-N-Acetyl-glucosaminyl-(1,2)-mannosyl-(1,3)-],[N-acetyl-glucosaminyl-(1,2)-mannosyl-(1,6)-]mannosyl-(1,4)-N-acetyl-glucosaminyl-(1,4)-[fucosyl-(1,6)]-N-acetyl-glucosaminyl}asparagine | 0 | 0 | 0 | 0
dgtp[c] | dGTP | 0 | 0 | 0 | 0
dgtp[n] | dGTP | 0 | 0 | 0 | 0
cdp[n] | CDP | 0 | 0 | 0 | 0
dgdp[n] | dGDP | 0 | 0 | 0 | 0
dcdp[n] | dCDP | 0 | 0 | 0 | 0
dctp[c] | dCTP | 0 | 0 | 0 | 0
dctp[n] | dCTP | 0 | 0 | 0 | 0
datp[n] | dATP | 0 | 0 | 0 | 0
dadp[n] | dADP | 0 | 0 | 0 | 0
gdp[n] | GDP | 0 | 0 | 0 | 0
cholp[c] | Choline phosphate | 0 | 0 | 0 | 0
Ser/Thr[g] | protein-linked serine or threonine residue (O-glycosylation site) | 0 | 0 | 0 | 0
gam[e] | D-Glucosamine | 0 | 0 | 0 | 0
ppa[c] | Propionate (n-C3:0) | 0 | 0 | 0 | 0
h2co3[c] | carbonic acid | 0 | 0 | 0 | 0
prostge2[e] | Prostaglandin E2 | 0 | 0 | 0 | 0
andrstrn[r] | Androsterone | 0 | 0 | 0 | 0
lcts[g] | Lactose | 0 | 0 | 0 | 0
3mgcoa[m] | 3-Methylglutaconyl-CoA | 0 | 0 | 1 | 0
selnp[c] | Selenophosphate | 0 | 0 | 0 | 0
retinal[c] | Retinal | 0 | 0 | 0 | 0
dadp[c] | dADP | 0 | 0 | 0 | 0
cdp[c] | CDP | 0 | 0 | 0 | 0
dcdp[c] | dCDP | 0 | 0 | 0 | 0
cs_a,b_pre3[g] | chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 3 | 0 | 0 | 0 | 0
ksii_core4_pre2[g] | keratan sulfate II boisynthesis, precursor 2 | 0 | 0 | 0 | 0
amp[c] | AMP | 0 | 0 | 0 | 0
[NAME]] | ATP | 0 | 0 | 0 | 0
adp[n] | ADP | 0 | 0 | 0 | 0
cs_a,b_pre2[g] | chondroitin sulfate A (GalNAc4S-GlcA) and B (IdoA2S-GalNAc4S), precursor 2 | 0 | 0 | 0 | 0
cs_c_pre2[g] | chondroitin sulfate C (GalNAc6S-GlcA), precursor 2 | 0 | 0 | 0 | 0
cs_d_pre3[g] | chondroitin sulfate D (GlcNAc6S-GlcA2S), precursor 3 | 0 | 0 | 0 | 0
cs_e_pre3[g] | chondroitin sulfate E (GalNAc4,6diS-GlcA), precursor 3 | 0 | 0 | 0 | 0
m6mpdol_L[r] | (alpha-D-Mannosyl)6-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog | 0 | 0 | 0 | 0
m7mpdol_L[r] | (alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human liver homolog | 0 | 0 | 0 | 0
m6mpdol_U[r] | (alpha-D-Mannosyl)6-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog | 0 | 0 | 0 | 0
m7mpdol_U[r] | (alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol, human uterine homolog | 0 | 0 | 0 | 0
Ser-Gly/Ala-X-Gly[r] | protein-linked serine residue (glycosaminoglycan attachment site) | 0 | 0 | 0 | 0
[NAME]] | UDP-D-xylose | 0 | 0 | 0 | 0
xser[r] | [NAME] (protein) | 0 | 0 | 0 | 0
cit[c] | Citrate | 0 | 0 | 0 | 0
dpcoa[c] | Dephospho-CoA | 0 | 0 | 0 | 0
cit[e] | Citrate | 0 | 0 | 0 | 0
pgp_hs[c] | phosphatidyl glycerol phosphate (homo sapiens) | 0 | 0 | 0 | 0
[NAME]] | L-Alanine | 0 | 0 | 0 | 0
ksi_pre19[g] | keratan sulfate I biosynthesis, precursor 19 | 0 | 0 | 0 | 0
[NAME]] | keratan sulfate I biosynthesis, precursor 22 | 0 | 0 | 0 | 0
ksi_pre25[g] | keratan sulfate I biosynthesis, precursor 25 | 0 | 0 | 0 | 0
ksi_pre28[g] | keratan sulfate I biosynthesis, precursor 28 | 0 | 0 | 0 | 0
ksi_pre31[g] | keratan sulfate I biosynthesis, precursor 31 | 0 | 0 | 0 | 0
ksi_pre34[g] | keratan sulfate I biosynthesis, precursor 34 | 0 | 0 | 0 | 0
ksii_core4_pre5[g] | keratan sulfate II biosynthesis, precursor 5 | 0 | 0 | 0 | 0
ksii_core4_pre8[g] | keratan sulfate II biosynthesis, precursor 8 | 0 | 0 | 0 | 0
ksii_core2_pre5[g] | keratan sulfate II biosynthesis, precursor 5 | 0 | 0 | 0 | 0
ksii_core2_pre8[g] | keratan sulfate II biosynthesis, precursor 8 | 0 | 0 | 0 | 0
ksi_pre4[g] | keratan sulfate I biosynthesis, precursor 4 | 0 | 0 | 0 | 0
ksi_pre7[g] | keratan sulfate I biosynthesis, precursor 7 | 0 | 0 | 0 | 0
ksi_pre10[g] | keratan sulfate I biosynthesis, precursor 10 | 0 | 0 | 0 | 0
ksi_pre13[g] | keratan sulfate I biosynthesis, precursor 13 | 0 | 0 | 0 | 0
ksi_pre16[g] | keratan sulfate I biosynthesis, precursor 16 | 0 | 0 | 0 | 0
nh4[c] | Ammonium | 0 | 0 | 0 | 0
hco3[e] | Bicarbonate | 0 | 0 | 0 | 0
hco3[c] | Bicarbonate | 0 | 0 | 0 | 0
mthgxl[c] | Methylglyoxal | 0 | 0 | 0 | 0
gam6p[c] | D-Glucosamine 6-phosphate | 0 | 0 | 0 | 0
acgpail_hs[c] | N-Acetyl-D-glucosaminylphosphatidylinositol | 0 | 0 | 0 | 0
g1p[c] | D-Glucose 1-phosphate | 0 | 0 | 0 | 0
25aics[c] | (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate | 0 | 0 | 0 | 0
12ppd-R[c] | (R)-Propane-1,2-diol | 0 | 0 | 0 | 0
lald-D[c] | D-Lactaldehyde | 0 | 0 | 0 | 0
acald[c] | Acetaldehyde | 0 | 0 | 0 | 0
succ[c] | Succinate | 0 | 0 | 0 | 0
44mzym[r] | 4,4-dimethylzymosterol | 0 | 0 | 0 | 0
fad[c] | Flavin adenine dinucleotide oxidized | 0 | 0 | 0 | 0
dnad[c] | Deamino-NAD+ | 0 | 0 | 0 | 0
nicrnt[c] | Nicotinate D-ribonucleotide | 0 | 0 | 0 | 0
estrone[c] | Estrone | 0 | 0 | 0 | 0
ksi_pre36[g] | keratan sulfate I biosynthesis, precursor 36 | 0 | 0 | 0 | 0
ksii_core4_pre10[g] | keratan sulfate II biosynthesis, precursor 10 | 0 | 0 | 0 | 0
ksii_core2_pre10[g] | keratan sulfate II biosynthesis, precursor 10 | 0 | 0 | 0 | 0
6pgl[r] | 6-phospho-D-glucono-1,5-lactone | 0 | 0 | 0 | 0
hista[e] | Histamine | 0 | 0 | 0 | 0
malt[l] | Maltose | 0 | 0 | 0 | 0
mi1345p[c] | 1D-myo-Inositol 1,3,4,5-tetrakisphosphate | 0 | 0 | 0 | 0
mi134p[c] | 1D-myo-Inositol 1,3,4-trisphosphate | 0 | 0 | 0 | 0
mi145p[c] | 1D-myo-Inositol 1,4,5-trisphosphate | 0 | 0 | 0 | 0
malttr[l] | Maltotriose | 0 | 0 | 0 | 0
pristcoa[x] | [NAME] | 0 | 0 | 0 | 0
prostgh2[c] | [NAME] | 0 | 0 | 0 | 0
6pgc[r] | 6-Phospho-D-gluconate | 0 | 0 | 0 | 0
pail45p_hs[c] | phosphatidylinositol 4,5-bisphosphate (Homo sapiens) | 0 | 0 | 0 | 0
selmeth[c] | Selenomethionine | 0 | 0 | 0 | 0
seasmet[c] | [NAME] | 0 | 0 | 0 | 0
thm[c] | Thiamin | 0 | 0 | 0 | 0