Spreadsheet: 5747d169-e5cc-4f45-ae72-d9ae3ebc1ef6
Sheet: Sheet1

Representative Public ID | [NAME] | [NAME] | Coincidence Cluster . | p value | Change | Fold change | Probe Set ID | OMIM | Ensembl | UniGene ID | [NAME] | [NAME] | Unnamed: 13 | GO Biological Process Description | GO Molecular Function Description | GO Cellular Component Description | [NAME] | [NAME]
U27516 | RAD52 homolog (S. cerevisiae) | RAD52 | 7_3 | 0.035137667 | increased | 1.235811975001187 | 1043_s_at | 600392 | ENSG00000002016 | 552577 | 5893 | NM_002879 /// NM_134422 /// NM_134423 /// NM_134424 |  | DNA repair /// double-strand break repair /// DNA recombination /// mitotic recombination /// meiotic recombination | DNA binding | nucleus | --- | ---
M83667 | CCAAT/enhancer binding protein (C/EBP), delta | CEBPD | 7_3 | 0.017285313 | increased | 1.360246847987122 | 1052_s_at | 116898 | ENSG00000180733 | 440829 | 1052 | NM_005195 |  | transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter | DNA binding | nucleus | --- | ---
U02687 | fms-related tyrosine kinase 3 | FLT3 | 1_6 | 0.01459859 | increased | 1.84451848122006 | 1065_at | 136351 /// 601626 | ENSG00000122025 | 507590 | 2322 | NM_004119 |  | protein amino acid phosphorylation /// transmembrane receptor [NAME] signaling pathway /// positive regulation of cell proliferation | receptor activity /// vascular endothelial growth factor receptor activity /// ATP binding /// transferase activity | integral to plasma membrane /// membrane | --- | ---
M65066 | [NAME], cAMP-dependent, regulatory, type I, beta | PRKAR1B | 4_11 | 0.024812024 | decreased | 1.744696329926285 | 1091_at | 176911 | --- | 534340 | 5575 | NM_002735 |  | protein amino acid phosphorylation /// protein amino acid phosphorylation /// signal transduction | nucleotide binding /// cAMP-dependent protein kinase regulator activity /// cAMP-dependent protein kinase regulator activity /// kinase activity /// 3',5'-cAMP binding | cAMP-dependent protein kinase complex /// cAMP-dependent protein kinase complex | G_Protein_Signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
L27943 | cytidine deaminase | CDA | 7_3 | 0.02265702 | increased | 1.729283781668308 | 1117_at | 123920 | ENSG00000158825 | 466910 | 978 | NM_001785 |  | nucleobase, nucleoside, nucleotide and nucleic acid metabolism /// cytidine metabolism | cytidine deaminase activity /// zinc ion binding /// hydrolase activity | --- | Pyrimidine metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00240+3.5.4.5
D88799 | protocadherin gamma subfamily B, 7 | PCDHGB7 | 1_1 | 0.001609551 | increased | 1.537215007868659 | 1169_at | 606304 | ENSG00000081853 | --- | 56099 | /// NM_018927 /// NM_032101 |  | cell adhesion /// homophilic cell adhesion | calcium ion binding /// protein binding | membrane /// integral to membrane | --- | ---
U83600 | tumor necrosis factor receptor superfamily, member 25 | TNFRSF25 | 8_10 | 0.0202183 | decreased | 1.116602506085193 | 1210_s_at | 603366 | ENSG00000171680 | 462529 | 8718 | NM_003790 /// NM_148965 /// NM_148966 /// NM_148967 /// NM_148968 /// NM_148969 /// NM_148970 /// NM_148971 /// NM_148972 /// NM_148973 /// NM_148974 |  | apoptosis /// immune response /// signal transduction /// cell surface receptor linked signal transduction /// induction of apoptosis by extracellular signals /// regulation of apoptosis | receptor activity /// transmembrane receptor activity /// tumor necrosis factor receptor activity /// protein binding | cytosol /// integral to plasma membrane /// membrane | Apoptosis | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm
M16594 | glutathione S-transferase A1 /// glutathione S-transferase A2 /// glutathione S-transferase A3 | GSTA1 /// GSTA2 /// GSTA3 | 8_10 | 0.025671654 | decreased | 1.861076579114298 | 1260_s_at | 138359 /// 138360 /// 605449 | ENSG00000187919 /// ENSG00000096087 /// ENSG00000174156 | 94107 | 2938 /// 2939 /// 2940 | NM_000846 /// NM_000847 /// NM_145740 |  | metabolism /// metabolism /// response to stress | glutathione transferase activity /// transferase activity /// glutathione transferase activity /// glutathione transferase activity /// glutathione transferase activity | cytoplasm | Glutathione metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00480+2.5.1.18
L11329 | dual specificity phosphatase 2 | [NAME] | 10_10 | 0.026386747 | decreased | 1.252623310332417 | 1292_at | 603068 | ENSG00000158050 | 1183 | 1844 | NM_004418 |  | inactivation of MAPK /// protein amino acid dephosphorylation /// protein amino acid dephosphorylation | protein tyrosine phosphatase activity /// protein tyrosine/threonine phosphatase activity /// hydrolase activity /// MAP kinase phosphatase activity | nucleus | --- | ---
D14533 | xeroderma pigmentosum, complementation group A | XPA | 6_10 | 0.015251903 | decreased | 1.057277509762031 | 1308_g_at | 278700 | ENSG00000136936 | 288867 | 7507 | NM_000380 |  | nucleotide-excision repair | damaged DNA binding /// protein binding | nucleus | --- | ---
S69369 | paired box gene 3 (Waardenburg syndrome 1) | PAX3 | 6_10 | 0.009914961 | decreased | 1.942019297758287 | 1344_at | 122880 /// 148820 /// 193500 /// 268220 /// 606597 | ENSG00000135903 | 42146 | 5077 | NM_000438 /// NM_013942 /// NM_181457 /// NM_181458 /// NM_181459 /// NM_181460 /// NM_181461 |  | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// apoptosis /// development /// neurogenesis /// perception of sound | transcription factor activity /// transcription factor activity | nucleus | --- | ---
S72043 | metallothionein 3 (growth inhibitory factor (neurotrophic)) | MT3 | 5_2 | 0.000100304 | increased | 2.051967141573229 | 1346_at | 139255 | ENSG00000087250 | 73133 | 4504 | NM_005954 |  | response to hypoxia /// metal ion homeostasis /// cell proliferation /// removal of superoxide radicals /// negative regulation of cell growth /// negative regulation of dendrite morphogenesis | copper ion binding /// zinc ion binding /// antioxidant activity /// metal ion binding | synaptic vesicle | --- | ---
X95632 | abl interactor 2 | ABI2 | 3_10 | 0.003491301 | decreased | 1.7599111424707 | 135_g_at | 606442 | ENSG00000138443 | 471156 | 10152 | NM_005759 |  | cytoskeleton organization and biogenesis /// actin polymerization and/or depolymerization /// cell migration | DNA binding /// SH3/SH2 adaptor activity /// cytoskeletal adaptor activity /// SH3 domain binding /// kinase binding | nucleus /// cytoplasm /// cytoplasm /// lamellipodium /// filopodium | --- | ---
U07695 | EPH receptor B4 | EPHB4 | 4_11 | 0.010259488 | decreased | 2.014987422406468 | 1351_at | 600011 | ENSG00000196411 | 437008 | 2050 | NM_004444 |  | protein amino acid phosphorylation /// transmembrane receptor [NAME] signaling pathway /// cell proliferation /// organogenesis | protein-tyrosine kinase activity /// receptor activity /// ephrin receptor activity /// ATP binding /// transferase activity | integral to plasma membrane /// membrane | --- | ---
M87770 | fibroblast growth factor receptor 2 (bacteria-expressed kinase, [NAME] growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome) | FGFR2 | 6_10 | 0.033204923 | decreased | 1.821022000211322 | 1363_at | 101200 /// 101400 /// 101600 /// 123150 /// 123500 /// 123790 /// 137215 /// 176943 | ENSG00000066468 | 533683 | 2263 | NM_000141 /// NM_022969 /// NM_022970 /// NM_022971 /// NM_022972 /// NM_022973 /// NM_022974 /// NM_022975 /// NM_022976 /// NM_023028 /// NM_023029 /// NM_023030 /// NM_023031 |  | protein amino acid phosphorylation /// protein amino acid phosphorylation /// cell growth | protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// protein-tyrosine kinase activity /// receptor activity /// fibroblast growth factor receptor activity /// ATP binding /// heparin binding /// transferase activity | membrane /// integral to membrane | --- | ---
D26561 | --- | --- | 2_7 | 0.013871185 | decreased | 1.281074481559686 | 1414_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
[NAME] | Src-like-adaptor | SLA | 1_3 | 0.004873927 | increased | 1.886559119767333 | 1427_g_at | 601099 | ENSG00000155926 | 75367 | 6503 | NM_006748 |  | intracellular signaling cascade | SH3/SH2 adaptor activity | --- | --- | ---
AF014958 | chemokine (C-C motif) receptor-like 2 | CCRL2 | 6_10 | 0.011805087 | decreased | 1.472479783730622 | 1445_at | 608379 | ENSG00000188268 | 458436 | 9034 | NM_003965 |  | chemotaxis /// G-protein coupled receptor protein signaling pathway /// G-protein coupled receptor protein signaling pathway /// antimicrobial humoral response (sensu Vertebrata) | rhodopsin-like receptor activity /// receptor activity /// C-C chemokine receptor activity | integral to plasma membrane /// integral to membrane | GPCRDB_Class_A_Rhodopsin-like | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm
S75881 | [NAME] myeloblastosis viral oncogene homolog (avian)-like 1 | MYBL1 | 4_8 | 0.026170992 | decreased | 2.670818789211564 | 1465_s_at | 159405 | ENSG00000185697 | 445898 | 4603 | XM_034274 |  | regulation of transcription, DNA-dependent | DNA binding /// transcriptional activator activity | nucleus | --- | ---
D84361 | src homology 2 domain containing transforming protein C3 | SHC3 | 8_10 | 0.017841812 | decreased | 1.538239953205235 | 1511_at | 605263 | ENSG00000148082 | 137570 | 53358 | NM_016848 |  | epidermal growth factor receptor signaling pathway /// intracellular signaling cascade /// central nervous system development | signal transducer activity | --- | Integrin-mediated_cell_adhesion_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Integrin-mediated_cell_adhesion_KEGG/Hs_Integrin-mediated_cell_adhesion_KEGG.htm
HG4074-HT4344 | --- | --- | 10_10 | 0.030610549 | decreased | 1.723956605039363 | 1516_g_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
U47011 | fibroblast growth factor 8 (androgen-induced) | FGF8 | 4_11 | 0.01297203 | decreased | 2.151554489878028 | 1526_i_at | 600483 | ENSG00000107831 | 57710 | 2253 | NM_006119 /// NM_033163 /// NM_033164 /// NM_033165 |  | regulation of cell cycle /// signal transduction /// cell-cell signaling /// gastrulation /// cell proliferation /// morphogenesis | growth factor activity | extracellular space | --- | ---
U68723 | checkpoint suppressor 1 | CHES1 | 4_11 | 0.032755207 | decreased | 2.856764267470745 | 1535_at | 602628 | ENSG00000053254 | 408428 | 1112 | NM_005197 |  | DNA damage checkpoint /// G2 phase of mitotic cell cycle /// transcription /// regulation of transcription, DNA-dependent | transcription factor activity | nucleus | --- | ---
X07109 | protein kinase C, beta 1 | PRKCB1 | 3_11 | 0.032538357 | decreased | 3.611583054212629 | 160029_at | 176970 | ENSG00000166501 | 460355 | 5579 | NM_002738 /// NM_212535 |  | protein amino acid phosphorylation /// intracellular signaling cascade | protein kinase C activity /// calcium ion binding /// ATP binding /// transferase activity /// diacylglycerol binding | cytoplasm /// plasma membrane | G_Protein_Signaling /// Wnt_signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction /// Phosphatidylinositol signaling system | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP04070+2.7.1.37
HG3187-HT3366 | --- | --- | 9_11 | 0.005684818 | decreased | 1.478646209561799 | 1629_s_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
U47931 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | GNB3 | 3_10 | 0.005684001 | decreased | 2.56173889545458 | 165_g_at | 139130 /// 145500 | ENSG00000111664 | 534315 | 2784 | NM_002075 |  | signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein coupled receptor protein signaling pathway /// regulation of blood pressure | GTPase activity /// signal transducer activity | [NAME] complex | G_Protein_Signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
X69950 | Wilms tumor 1 | WT1 | 1_1 | 0.02284141 | increased | 2.407496888791037 | 1683_at | 136680 /// 194070 /// 194072 /// 194080 /// 256370 /// 607102 | ENSG00000184937 | 408453 | 7490 | NM_000378 /// NM_024424 /// NM_024425 /// NM_024426 |  | transcription /// regulation of transcription, DNA-dependent /// regulation of transcription, DNA-dependent /// cell cycle /// negative regulation of cell cycle | nucleic acid binding /// transcription factor activity /// transcription factor activity /// zinc ion binding | nucleus /// nucleus | --- | ---
X82554 | S-phase response (cyclin-related) | SPHAR | 2_11 | 0.024721899 | decreased | 2.044754159092635 | 1686_g_at | --- | ENSG00000168118 | 511754 | 10638 | NM_006542 |  | regulation of cell cycle /// DNA replication | --- | --- | --- | ---
HG884-HT884 | --- | --- | 9_11 | 0.003208486 | decreased | 2.752288650072205 | 1725_s_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
U86214 | caspase 10, apoptosis-related cysteine protease | CASP10 | 1_3 | 0.034007258 | increased | 2.427580569000876 | 1766_g_at | 137215 /// 601762 /// 603909 /// 605027 | ENSG00000003400 | 5353 | 843 | NM_001230 /// NM_032974 /// NM_032976 /// NM_032977 |  | proteolysis and peptidolysis /// induction of apoptosis /// regulation of apoptosis | protein binding /// cysteine-type peptidase activity /// caspase activity /// caspase activity | --- | Apoptosis /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
X14885 | transforming growth factor, beta 3 | TGFB3 | 3_9 | 0.006603238 | decreased | 2.48371818557984 | 1767_s_at | 190230 | ENSG00000119699 | 2025 | 7043 | NM_003239 |  | regulation of cell cycle /// signal transduction /// cell-cell signaling /// cell proliferation /// organogenesis /// cell growth | transforming growth factor beta receptor binding /// growth factor activity | --- | --- | ---
M16750 | [NAME] | PIM1 | 1_3 | 0.032479115 | increased | 1.483461895030286 | 1779_s_at | 164960 | ENSG00000137193 | 81170 | 5292 | NM_002648 |  | protein amino acid phosphorylation /// development | protein serine/threonine kinase activity /// ATP binding /// transferase activity | nucleus /// cytoplasm | --- | ---
X12556 | [NAME] cell line derived transforming sequence | [NAME] | 10_10 | 0.010634825 | decreased | 1.371638842267305 | 1807_g_at | 311030 | ENSG00000101977 | 387262 | 4168 | NM_005369 |  | intracellular signaling cascade | guanyl-nucleotide exchange factor activity | membrane fraction /// cytosol /// cytoskeleton | --- | ---
S82470 | leukocyte receptor cluster (LRC) member 4 | LENG4 | 4_11 | 0.025244057 | decreased | 1.802208545151633 | 181_g_at | 606048 | ENSG00000125505 | 467279 | 79143 | NM_024298 |  | --- | receptor activity | --- | --- | ---
L78132 | lectin, galactoside-binding, soluble, 8 (galectin 8) | LGALS8 | 4_11 | 0.00504002 | decreased | 2.201646242688441 | 1846_at | 606099 | ENSG00000116977 | 4082 | 3964 | NM_006499 /// NM_201543 /// NM_201544 /// NM_201545 |  | --- | sugar binding /// sugar binding | extracellular space | --- | ---
D38122 | Fas ligand (TNF superfamily, member 6) | FASLG | 2_10 | 0.006770131 | decreased | 1.364152246474593 | 1858_at | 134638 /// 152700 | ENSG00000117560 | 2007 | 356 | NM_000639 |  | apoptosis /// induction of apoptosis /// immune response /// signal transduction /// cell-cell signaling /// positive regulation of I-kappaB kinase/NF-kappaB cascade | tumor necrosis factor receptor binding | extracellular region /// integral to plasma membrane /// membrane | Apoptosis /// Apoptosis_GenMAPP /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_GenMAPP/Hs_Apoptosis_GenMAPP.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
U58334 | tumor protein p53 binding protein, 2 | TP53BP2 | 6_10 | 0.006827012 | decreased | 1.242892853920526 | 1860_at | 602143 | ENSG00000143514 | 523968 | 7159 | NM_005426 |  | regulation of cell cycle /// apoptosis /// signal transduction | SH3/SH2 adaptor activity | cytoplasm | --- | ---
U67092 | ataxia telangiectasia mutated (includes complementation groups A, C and D) | ATM | 3_10 | 0.025334204 | decreased | 1.685969951845985 | 1862_at | 114480 /// 208900 /// 607585 | ENSG00000149311 | 435561 | 472 | NM_000051 /// NM_138292 /// NM_138293 |  | DNA repair /// regulation of transcription, DNA-dependent /// meiotic recombination /// signal transduction /// negative regulation of cell cycle | DNA binding /// transcription factor activity /// protein serine/threonine kinase activity /// transferase activity /// phosphotransferase activity, alcohol group as acceptor | intracellular /// nucleus | Cell_cycle_KEGG /// G1_to_S_cell_cycle_Reactome /// Ovarian_Infertility_Genes | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G1_to_S_cell_cycle_Reactome/Hs_G1_to_S_cell_cycle_Reactome.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Ovarian_Infertility_Genes/Hs_Ovarian_Infertility_Genes.htm
AF015950 | telomerase reverse transcriptase | TERT | 10_10 | 0.018020718 | decreased | 1.374732276315024 | 1869_at | 187270 | ENSG00000164362 | 492203 | 7015 | NM_003219 /// NM_198253 /// NM_198254 /// NM_198255 |  | RNA-dependent DNA replication /// telomerase-dependent telomere maintenance | DNA binding /// telomeric template [NAME] reverse transcriptase activity /// telomeric template [NAME] reverse transcriptase activity /// RNA binding /// RNA-directed DNA polymerase activity /// transferase activity /// telomeric DNA binding | chromosome, telomeric region /// nucleus /// telomerase holoenzyme complex | --- | ---
U11791 | cyclin H | CCNH | 3_9 | 0.02966186 | decreased | 1.795905286607769 | 1924_at | 601953 | ENSG00000134480 | 146607 | 902 | NM_001239 |  | regulation of cyclin dependent protein kinase activity /// DNA repair /// transcription /// regulation of transcription, DNA-dependent | --- | nucleus | Cell_cycle_KEGG /// G1_to_S_cell_cycle_Reactome /// RNA_transcription_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G1_to_S_cell_cycle_Reactome/Hs_G1_to_S_cell_cycle_Reactome.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_RNA_transcription_Reactome/Hs_RNA_transcription_Reactome.htm
M60614 | Wilms tumor associated protein | WIT-1 | 2_10 | 0.034663076 | decreased | 4.144613680553298 | 1947_g_at | 607899 | ENSG00000183242 | 546393 | 51352 | NM_015855 |  | cell proliferation | --- | --- | --- | ---
AB004922 | SMAD, mothers against DPP homolog 3 (Drosophila) | SMAD3 | 4_11 | 0.00649999 | decreased | 1.850839538400972 | 1950_s_at | 603109 | ENSG00000166949 | 36915 | 4088 | NM_005902 |  | transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// transforming growth factor beta receptor signaling pathway | transcription factor activity | intracellular | --- | ---
D88674 | antizyme inhibitor 1 | AZIN1 | 9_11 | 0.022976054 | decreased | 1.772354951402977 | 1959_at | 607909 | ENSG00000155096 | 459106 | 51582 | NM_015878 /// NM_148174 |  | polyamine biosynthesis | catalytic activity /// enzyme inhibitor activity | --- | Circadian_Exercise | [NAME]
U18334 | --- | --- | 8_10 | 0.022944405 | decreased | 2.532893714041334 | 1966_i_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
[NAME] | nucleolar protein 1, 120kDa | NOL1 | 4_10 | 0.025285206 | decreased | 3.448800674069648 | 1979_s_at | 164031 | ENSG00000111641 | 534334 | 4839 | NM_006170 |  | regulation of cell cycle /// positive regulation of cell proliferation | methyltransferase activity /// transferase activity | nucleolus | --- | ---
X76079 | platelet-derived growth factor receptor, alpha polypeptide | PDGFRA | 3_10 | 0.02045789 | decreased | 1.973926554620655 | 1987_at | 173490 /// 606764 /// 607685 | ENSG00000134853 | 74615 | 5156 | NM_006206 |  | protein amino acid phosphorylation /// cell surface receptor linked signal transduction /// transmembrane receptor [NAME] signaling pathway /// cell proliferation | receptor activity /// platelet-derived growth factor alpha-receptor activity /// vascular endothelial growth factor receptor activity /// ATP binding /// transferase activity | integral to plasma membrane /// membrane | --- | ---
U34584 | BCL2-interacting killer (apoptosis-inducing) | BIK | 8_10 | 0.014824167 | decreased | 1.80898714921204 | 2011_s_at | 603392 | ENSG00000100290 | 475055 | 638 | NM_001197 |  | induction of apoptosis /// apoptotic program /// regulation of apoptosis | --- | integral to membrane | --- | ---
L20046 | excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G (Cockayne syndrome)) | ERCC5 | 9_11 | 0.003775608 | decreased | 1.769583604163069 | 2064_g_at | 133530 /// 214150 /// 278780 | ENSG00000134899 | 258429 | 2073 | NM_000123 |  | DNA repair /// transcription-coupled nucleotide-excision repair /// perception of sound | DNA binding /// single-stranded DNA binding /// nuclease activity /// endodeoxyribonuclease activity /// hydrolase activity | nucleus | --- | ---
S74221 | IK cytokine, down-regulator of HLA II | IK | 9_11 | 0.009986181 | decreased | 1.307686905363432 | 218_at | 600549 | ENSG00000113141 | 421245 | 3550 | NM_006083 |  | immune response /// cell-cell signaling | cytokine activity | extracellular space /// soluble fraction | --- | ---
S78467 | phosphatidylinositol glycan, class A (paroxysmal nocturnal hemoglobinuria) | PIGA | 6_10 | 0.01646121 | decreased | 1.789747199941802 | 221_s_at | 311770 | ENSG00000165195 | 137154 | 5277 | NM_002641 /// NM_020472 /// NM_020473 |  | biosynthesis | transferase activity, transferring glycosyl groups /// phosphatidylinositol N-acetylglucosaminyltransferase activity | endoplasmic reticulum membrane /// integral to membrane | --- | ---
M54914 | follicle stimulating hormone, beta polypeptide | FSHB | 7_3 | 0.016808311 | increased | 1.34165201499756 | 230_s_at | 136530 | ENSG00000131808 | 36975 | 2488 | NM_000510 |  | ovarian follicle development /// signal transduction /// spermatogenesis /// female gamete generation /// pregnancy | follicle-stimulating hormone activity /// protein heterodimerization activity | extracellular region /// soluble fraction | --- | ---
[NAME] | [NAME] D (lysosomal aspartyl protease) | CTSD | 7_6 | 0.013836143 | increased | 3.705471200032836 | 239_at | 116840 | ENSG00000117984 | 546248 | 1509 | NM_001909 |  | proteolysis and peptidolysis | cathepsin D activity /// pepsin A activity /// peptidase activity | extracellular region /// lysosome | --- | ---
L41066 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | NFATC4 | 4_10 | 0.024652228 | decreased | 1.012003593423284 | 249_at | 602699 | ENSG00000100968 | 77810 | 4776 | NM_004554 |  | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// inflammatory response | transcription factor activity /// transcription coactivator activity | nucleus | --- | ---
L41067 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | NFATC3 | 10_10 | 0.021333622 | decreased | 1.726200015077187 | 250_at | 602698 | ENSG00000072736 | 341716 | 4775 | NM_004555 /// NM_173163 /// NM_173164 /// NM_173165 |  | regulation of transcription from RNA polymerase II promoter /// inflammatory response | transcription factor activity /// transcription coactivator activity | nucleus | --- | ---
L42324 | G protein-coupled receptor 18 | GPR18 | 7_3 | 0.021895028 | increased | 1.575168299515602 | 252_at | 602042 | ENSG00000125245 | 549036 | 2841 | NM_005292 |  | signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein coupled receptor protein signaling pathway | rhodopsin-like receptor activity /// receptor activity /// purinergic nucleotide receptor activity, G-protein coupled | integral to membrane /// integral to membrane | GPCRDB_Class_A_Rhodopsin-like2 /// GPCRDB_Other | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like2/Hs_GPCRDB_Class_A_Rhodopsin-like2.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Other/Hs_GPCRDB_Other.htm
M23533 | adrenergic, alpha-2A-, receptor | ADRA2A | 6_10 | 0.02853151 | decreased | 1.812103090317227 | 264_at | 104210 | ENSG00000150594 | 249159 | 150 | NM_000681 |  | activation of MAPK /// cell motility /// signal transduction /// G-protein coupled receptor protein signaling pathway /// negative regulation of adenylate cyclase activity /// [NAME] protein signal transduction /// Rho protein signal transduction /// positive regulation of cell proliferation /// actin cytoskeleton organization and biogenesis | rhodopsin-like receptor activity /// receptor activity /// adrenoceptor activity /// alpha2-adrenergic receptor activity /// potassium channel regulator activity | plasma membrane /// integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Monoamine_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Monoamine_GPCRs/Hs_Monoamine_GPCRs.htm
[NAME] | high-mobility group nucleosome binding domain 1 | HMGN1 | 6_10 | 0.004372807 | decreased | 1.621855328940191 | 306_s_at | 163920 | ENSG00000198875 | 356285 | 3150 | NM_004965 |  | --- | DNA binding /// DNA binding /// RNA polymerase II transcription factor activity /// positive transcription elongation factor activity | chromatin /// chromatin /// nucleus | --- | ---
U92642 | G protein-coupled receptor 45 | [NAME] | 8_10 | 0.025790901 | decreased | 1.870147553037682 | 31334_at | 604838 | ENSG00000135973 | 129701 | 11250 | NM_007227 |  | signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein coupled receptor protein signaling pathway /// neurogenesis | rhodopsin-like receptor activity /// receptor activity | integral to plasma membrane /// integral to membrane | GPCRDB_Class_A_Rhodopsin-like2 | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like2/Hs_GPCRDB_Class_A_Rhodopsin-like2.htm
AF055989 | potassium voltage-gated channel, Shaw-related subfamily, member 3 | [NAME] | 8_10 | 3.12e-05 | decreased | 1.896394062080208 | 31341_at | 176264 | [NAME] | 467146 | 3748 | NM_004977 |  | cation transport /// potassium ion transport | voltage-gated potassium channel activity /// protein binding | membrane fraction /// voltage-gated potassium channel complex /// membrane /// integral to membrane | --- | ---
L10403 | pro-platelet basic protein-like 2 | PPBPL2 | 3_10 | 0.00014315 | decreased | 1.644742011214577 | 31349_at | --- | --- | 3134 | 10895 | --- |  | transcription from RNA polymerase II promoter /// respiratory gaseous exchange | transcription factor activity | nucleus | --- | ---
AF012270 | retinal pigment epithelium-derived rhodopsin homolog | RRH | 7_3 | 0.033168006 | increased | 1.997153385988566 | 31408_at | 605224 | ENSG00000180245 | 352262 | 10692 | NM_006583 |  | signal transduction /// G-protein coupled receptor protein signaling pathway /// visual perception | rhodopsin-like receptor activity /// receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm
AJ000503 | dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2) | DCT | 8_10 | 0.033425464 | decreased | 1.256535204276004 | 31465_g_at | 191275 | ENSG00000080166 | 301865 | 1638 | NM_001922 |  | melanin metabolism /// melanin biosynthesis from tyrosine /// melanin biosynthesis from tyrosine /// metabolism /// epidermis development | dopachrome isomerase activity /// dopachrome isomerase activity /// copper ion binding /// oxidoreductase activity /// isomerase activity | integral to membrane /// integral to membrane | Tyrosine metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00350+5.3.3.12
AL031393 | MRNA; cDNA DKFZp686H0940 (from clone DKFZp686H0940) | --- | 7_3 | 0.025144657 | increased | 2.238338693926668 | 31471_at | --- | --- | 522621 | --- | --- |  | --- | --- | --- | --- | ---
[NAME] | T cell receptor beta chain variable region (TCRB) mRNA, 5' end. | --- | 6_10 | 0.03336065 | decreased | 1.467391786190824 | 31563_at | --- | --- | 521251 | --- | --- |  | --- | --- | --- | --- | ---
Z70200 | activating signal cointegrator 1 complex subunit 3-like 1 | ASCC3L1 | 6_10 | 0.019136162 | decreased | 2.201595930383754 | 31593_at | 601664 | ENSG00000144028 | 246112 | 23020 | NM_014014 |  | nuclear mRNA splicing, via spliceosome /// RNA splicing | nucleic acid binding /// ATP-dependent RNA helicase activity /// helicase activity /// ATP binding /// hydrolase activity | spliceosome complex | --- | ---
[NAME] | UDP-galactose-4-epimerase | GALE | 6_10 | 0.014922189 | decreased | 1.87597571668658 | 31598_s_at | 230350 /// 606953 | ENSG00000117308 | 76057 | 2582 | NM_000403 /// NM_001008216 |  | carbohydrate metabolism /// galactose metabolism /// nucleotide-sugar metabolism | UDP-glucose 4-epimerase activity /// UDP-glucose 4-epimerase activity /// isomerase activity | --- | Galactose metabolism /// Nucleotide sugars metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00052+5.1.3.2 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00520+5.1.3.2
AJ224171 | [NAME], family 1D, member 1 | SCGB1D1 | 8_10 | 0.012742639 | decreased | 1.2973425689852 | 31612_at | --- | ENSG00000168515 | 202686 | 10648 | NM_006552 |  | --- | --- | extracellular space | --- | ---
AF030427 | [NAME]-I cell membrane-associated glycoprotein | T1A-2 | 6_10 | 0.028784223 | decreased | 0.9501523429342121 | 31617_at | 608863 | ENSG00000162493 | 468675 | 10630 | NM_001006624 /// NM_001006625 /// NM_006474 /// NM_198389 |  | --- | --- | integral to plasma membrane /// integral to membrane | --- | ---
AL080191 | DKFZP434A062 protein | DKFZP434A062 | 8_10 | 0.00296038 | decreased | 1.622114807308276 | 31660_at | --- | --- | 226001 | 26102 | --- |  | --- | --- | --- | --- | ---
M20543 | [NAME], alpha 1, skeletal muscle | ACTA1 | 7_3 | 0.019796899 | increased | 1.373110085227276 | 31737_at | 102610 /// 256030 | ENSG00000143632 | 1288 | 58 | NM_001100 |  | muscle development | motor activity /// structural constituent of cytoskeleton /// protein binding | actin filament | Smooth_muscle_contraction /// Striated_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Striated_muscle_contraction/Hs_Striated_muscle_contraction.htm
W27128 | Serine/threonine kinase 35 | STK35 | 3_10 | 0.031109224 | decreased | 3.028701435347743 | 31757_at | --- | ENSG00000125834 | 100057 | 140901 | NM_080836 |  | protein amino acid phosphorylation | protein serine/threonine kinase activity /// ATP binding /// transferase activity | --- | --- | ---
AC006293 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 | KIR3DL3 | 7_3 | 0.028635558 | increased | 1.151953654311521 | 31780_f_at | --- | ENSG00000125498 | --- | 115653 | NM_153443 |  | --- | --- | --- | --- | ---
AL022329 | adrenergic, beta, receptor kinase 2 | ADRBK2 | 1_5 | 0.025444019 | increased | 2.534265616809186 | 31795_at | 109636 | ENSG00000100077 | 517493 | 157 | NM_005160 |  | protein amino acid phosphorylation /// signal transduction | G-protein coupled receptor kinase activity /// signal transducer activity /// ATP binding /// transferase activity /// beta-adrenergic-receptor kinase activity | --- | --- | ---
AL050136 | Similar to family with sequence similarity 9, member C | --- | 4_11 | 0.010044485 | decreased | 1.900510081729235 | 31800_at | --- | --- | 530171 | 441347 | XM_496974 |  | --- | --- | --- | --- | ---
AL050390 | ankyrin repeat and MYND domain containing 2 | ANKMY2 | 8_10 | 0.01991858 | decreased | 1.495627984998262 | 31852_at | --- | ENSG00000106524 | 157378 | 57037 | NM_020319 |  | --- | --- | --- | --- | ---
AJ005016 | ATP-binding cassette, sub-family F (GCN20), member 2 | ABCF2 | 7_3 | 0.004496473 | increased | 1.585824465745566 | 31878_at | --- | ENSG00000033050 | 438823 | 10061 | NM_005692 /// NM_007189 |  | transport | nucleotide binding /// transporter activity /// ATP binding /// ATP binding /// ATPase activity | mitochondrial membrane /// ATP-binding cassette (ABC) transporter complex | --- | ---
L40399 | mutL homolog 3 (E. coli) | MLH3 | 9_11 | 0.005040365 | decreased | 1.978336974933759 | 31884_at | 114500 /// 604395 | ENSG00000119684 | 279843 | 27030 | NM_014381 |  | mismatch repair /// meiotic recombination | satellite DNA binding /// protein binding /// ATP binding | nucleus | --- | ---
J04469 | [NAME], mitochondrial 1 (ubiquitous) | CKMT1A | 5_2 | 0.029149015 | increased | 2.259418751750214 | 31887_at | --- | --- | --- | 548596 | --- |  | --- | --- | --- | Urea cycle and metabolism of amino groups /// Arginine and proline metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00220+2.7.3.2 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00330+2.7.3.2
X58288 | protein tyrosine phosphatase, receptor type, M | PTPRM | 8_10 | 0.002345864 | decreased | 1.568278089835826 | 31892_at | 176888 | [NAME] | 49774 | 5797 | NM_002845 |  | protein amino acid dephosphorylation | receptor activity /// transmembrane receptor protein tyrosine phosphatase activity /// hydrolase activity | integral to plasma membrane /// membrane | --- | ---
AF049703 | E74-like factor 5 (ets domain transcription factor) | ELF5 | 3_10 | 0.00904822 | decreased | 1.47826299468137 | 31913_at | 605169 | ENSG00000135374 | 11713 | 2001 | NM_001422 /// NM_198381 |  | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// cell proliferation | DNA binding /// transcription factor activity | nucleus | --- | ---
AF004841 | cell adhesion molecule-related/down-regulated by oncogenes | CDON | 6_10 | 0.003084595 | decreased | 1.544703922015929 | 31920_at | 608707 | ENSG00000064309 | 530804 | 50937 | NM_016952 |  | cell adhesion | protein binding | membrane | --- | ---
AI028290 | tubby like protein 3 | TULP3 | 9_11 | 0.030076517 | decreased | 2.210012097964858 | 31944_at | 604730 | ENSG00000078246 | 524187 | 7289 | NM_003324 |  | regulation of transcription, DNA-dependent /// G-protein coupled receptor protein signaling pathway | phosphatidylinositol-4,5-bisphosphate binding | nucleus /// plasma membrane | --- | ---
X78202 | forkhead box G1B /// forkhead box G1A | FOXG1B /// FOXG1A | 10_10 | 0.031647613 | decreased | 0.9396506702313293 | 31946_s_at | 164874 /// 600779 | ENSG00000176165 | 525266 | 2290 /// 2291 | NM_005249 |  | transcription /// regulation of transcription, DNA-dependent /// regulation of transcription, DNA-dependent /// development /// brain development /// brain development | transcription factor activity | nucleus | --- | ---
AB023212 | pecanex homolog (Drosophila) | PCNX | 3_10 | 0.016737308 | decreased | 2.990425071953626 | 32012_at | --- | ENSG00000100731 | 158722 | 22990 | NM_014982 |  | --- | --- | integral to membrane | --- | ---
X99459 | adaptor-related protein complex 3, sigma 2 subunit | AP3S2 | 4_11 | 0.02755043 | decreased | 2.026577651820738 | 32030_at | 602416 | ENSG00000157823 | 546334 | 10239 | NM_005829 |  | transport /// intracellular protein transport | --- | Golgi apparatus /// clathrin vesicle coat | --- | ---
U66063 | calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma | CAMK2G | 9_11 | 0.005429492 | decreased | 1.500463464211184 | 32105_f_at | 602123 | [NAME] | 523045 | 818 | NM_001222 /// NM_172169 /// NM_172170 /// NM_172171 /// NM_172172 /// NM_172173 |  | protein amino acid phosphorylation /// protein amino acid phosphorylation /// signal transduction /// insulin secretion | protein serine/threonine kinase activity /// calcium- and calmodulin-dependent protein kinase activity /// protein-tyrosine kinase activity /// calcium-dependent protein serine/threonine phosphatase activity /// calmodulin binding /// ATP binding /// ATP binding /// kinase activity /// transferase activity | --- | Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
AB002405 | [NAME] | EVER1 | 4_8 | 0.022603362 | decreased | 2.55590661675719 | 32116_at | 226400 /// 605828 | ENSG00000141524 | 16165 | 11322 | NM_007267 |  | --- | --- | integral to membrane | --- | ---
AA928996 | THO complex 2 | [NAME] | 3_8 | 0.029379874 | decreased | 1.729817158750684 | 32125_at | 300395 | ENSG00000125676 | 149991 | 57187 | NM_020449 |  | nuclear mRNA splicing, via spliceosome /// mRNA-nucleus export /// transport | RNA binding | nucleus | --- | ---
M60828 | fibroblast growth factor 7 (keratinocyte growth factor) | FGF7 | 1_5 | 0.007559788 | increased | 1.984170271213503 | 32126_at | 148180 | ENSG00000140285 | 549033 | 2252 | NM_002009 |  | regulation of cell cycle /// signal transduction /// cell-cell signaling /// cell proliferation /// positive regulation of cell proliferation /// epidermis development /// response to wounding | growth factor activity | extracellular region | --- | ---
L07261 | adducin 1 (alpha) | [NAME] | 9_11 | 0.032832466 | decreased | 1.605591906409662 | 32146_s_at | 102680 /// 145500 | ENSG00000087274 | 183706 | 118 | NM_001119 /// NM_014189 /// NM_014190 /// NM_176801 |  | cytoskeleton organization and biogenesis | [NAME] binding /// structural constituent of cytoskeleton /// calmodulin binding /// calmodulin binding | cytoskeleton /// actin cytoskeleton /// membrane | --- | ---
AB023182 | --- | --- | 5_2 | 0.015765548 | increased | 1.245316567287882 | 32182_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AB028973 | chromosome 20 open reading frame 36 | C20orf36 | 8_10 | 0.008267099 | decreased | 1.552635507999956 | 32187_at | --- | ENSG00000196132 | 473317 | 55251 | NM_018257 |  | protein modification | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity | --- | --- | ---
AA160708 | chromosome 20 open reading frame 18 | C20orf18 | 7_3 | 0.028000317 | increased | 1.027294844257842 | 32203_at | --- | ENSG00000125826 | 247280 | 10616 | NM_006462 /// NM_031227 /// NM_031228 /// NM_031229 |  | protein ubiquitination | ubiquitin-protein ligase activity /// zinc ion binding | ubiquitin ligase complex | --- | ---
AF001383 | bridging integrator 1 | BIN1 | 8_10 | 0.003793372 | decreased | 1.557795481503396 | 32238_at | 601248 | ENSG00000136717 | 193163 | 274 | NM_004305 /// NM_139343 /// NM_139344 /// NM_139345 /// NM_139346 /// NM_139347 /// NM_139348 /// NM_139349 /// NM_139350 /// NM_139351 |  | cell proliferation /// regulation of endocytosis /// cell differentiation /// negative regulation of cell cycle | protein binding | nucleus /// cytoplasm /// actin cytoskeleton | --- | ---
M65292 | complement factor H /// complement factor H-related 1 | CFH /// CFHL1 | 9_11 | 0.017329871 | decreased | 2.436950525571628 | 32249_at | 134370 /// 235400 /// 134371 | ENSG00000000971 /// ENSG00000080910 | 154224 | 3075 /// 3078 | NM_000186 /// NM_001014975 /// NM_002113 |  | immune response /// complement activation, alternative pathway /// complement activation | --- | extracellular space /// extracellular space | --- | ---
AC003682 | zinc finger protein 549 | ZNF549 | 10_10 | 0.020043356 | decreased | 1.879344368962877 | 32333_at | --- | ENSG00000121406 | 467358 | 256051 | NM_153263 |  | regulation of transcription, DNA-dependent | nucleic acid binding /// zinc ion binding | nucleus | --- | ---
U92818 | --- | --- | 7_3 | 0.005029403 | increased | 1.767881096331409 | 32407_f_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
X68561 | Sp4 transcription factor | SP4 | 8_10 | 0.0300388 | decreased | 1.266287292576015 | 32411_at | 600540 | ENSG00000105866 | 520244 | 6671 | NM_003112 |  | transcription /// regulation of transcription from RNA polymerase II promoter | DNA binding /// RNA polymerase II transcription factor activity /// transcription coactivator activity /// zinc ion binding | nucleus | --- | ---
X96744 | paired box gene 7 | PAX7 | 7_3 | 0.026224225 | increased | 1.280686977241056 | 32474_at | 167410 /// 268220 | ENSG00000009709 | 113253 | 5081 | NM_002584 /// NM_013945 |  | regulation of transcription, DNA-dependent /// anti-apoptosis /// morphogenesis | transcription factor activity | nucleus | --- | ---
U93163 | melanoma antigen family B, 3 | MAGEB3 | 2_10 | 0.005930424 | decreased | 1.989907815912105 | 32476_at | 300152 | ENSG00000198798 | 113290 | 4114 | NM_002365 |  | --- | --- | --- | --- | ---
AF018253 | tumor necrosis factor receptor superfamily, member 11a, activator of NFKB | TNFRSF11A | 8_10 | 0.022775908 | decreased | 1.722088244060266 | 32479_at | 174810 /// 602080 /// 603499 | ENSG00000141655 | 204044 | 8792 | NM_003839 |  | immune response /// signal transduction /// cell-cell signaling /// perception of sound /// positive regulation of cell proliferation | receptor activity | integral to membrane | --- | ---
U94888 | chemokine binding protein 2 | CCBP2 | 5_2 | 0.006357364 | increased | 1.885172578557531 | 32484_at | 602648 | ENSG00000144648 | 185692 | 1238 | NM_001296 |  | chemotaxis /// immune response /// signal transduction /// G-protein coupled receptor protein signaling pathway /// development | rhodopsin-like receptor activity /// receptor activity /// C-C chemokine receptor activity /// C-X-C chemokine receptor activity | plasma membrane /// integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm
HG1763-HT1780 | --- | --- | 3_10 | 0.013717815 | decreased | 1.467391584159148 | 325_s_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AF106564 | neurofilament 3 (150kDa medium) | NEF3 | 9_11 | 0.003582474 | decreased | 1.870358168578792 | 32512_at | 162250 | ENSG00000104722 | 458657 | 4741 | NM_005382 |  | --- | structural constituent of cytoskeleton | neurofilament /// axon | --- | ---
X72012 | endoglin (Osler-Rendu-Weber syndrome 1) | ENG | 5_2 | 0.018831515 | increased | 1.316675695081535 | 32562_at | 131195 /// 187300 | ENSG00000106991 | 76753 | 2022 | NM_000118 |  | cell adhesion /// circulation /// organogenesis | protein binding | integral to plasma membrane | TGF_Beta_Signaling_Pathway | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_TGF_Beta_Signaling_Pathway/Hs_TGF_Beta_Signaling_Pathway.htm
X68836 | methionine adenosyltransferase II, alpha | MAT2A | 2_10 | 0.025625042 | decreased | 1.957709049688401 | 32571_at | 601468 | ENSG00000168906 | 516157 | 4144 | NM_005911 |  | one-carbon compound metabolism | magnesium ion binding /// methionine adenosyltransferase activity /// ATP binding /// transferase activity | --- | --- | ---
D28118 | zinc finger protein 161 | ZNF161 | 9_11 | 0.007707077 | decreased | 1.89140510125466 | 32628_at | 606747 | ENSG00000136451 | 463569 | 7716 | NM_007146 |  | transcription /// regulation of transcription from RNA polymerase II promoter /// cellular defense response | DNA binding /// specific RNA polymerase II transcription factor activity /// zinc ion binding | nucleus | --- | ---
D37931 | ribonuclease, RNase A family, 4 | RNASE4 | 9_11 | 0.032222711 | decreased | 1.628061774965966 | 32664_at | 601030 | ENSG00000181784 | 283749 | 6038 | [NAME] /// NM_194430 /// NM_194431 |  | mRNA cleavage | nucleic acid binding /// endonuclease activity /// pancreatic ribonuclease activity /// hydrolase activity | --- | --- | ---
M58526 | collagen, type IV, alpha 5 (Alport syndrome) | COL4A5 | 9_11 | 0.005101984 | decreased | 2.662717760570308 | 32667_at | 301050 /// 303630 | ENSG00000188153 | 369089 | 1287 | NM_000495 /// NM_033380 /// NM_033381 |  | phosphate transport | extracellular matrix structural constituent | [NAME] /// collagen type IV /// cytoplasm | --- | ---
D79995 | --- | --- | 1_5 | 0.008346212 | increased | 2.989061381083712 | 32671_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AF023462 | phytanoyl-CoA hydroxylase ([NAME] disease) | PHYH | 6_11 | 0.015958359 | decreased | 1.892654554265421 | 32724_at | 266500 /// 602026 | ENSG00000107537 | 498732 | 5264 | NM_006214 |  | lipid metabolism /// neurogenesis /// sensory perception /// visual perception /// perception of sound | electron transporter activity /// phytanoyl-CoA dioxygenase activity | peroxisome | --- | ---
AF034091 | mitochondrial ribosomal protein L40 | [NAME] | 8_10 | 0.005005913 | decreased | 1.528517902788455 | 32745_at | 605089 | ENSG00000185608 | 431307 | 64976 | NM_003776 |  | morphogenesis | structural constituent of ribosome | nucleus /// mitochondrion /// mitochondrial ribosome /// ribonucleoprotein complex | --- | ---
D50929 | eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa | EIF3S10 | 2_10 | 0.017294598 | decreased | 1.547941578507649 | 32785_at | 602039 | ENSG00000107581 | 523299 | 8661 | NM_003750 |  | protein biosynthesis /// regulation of translational initiation | translation initiation factor activity | eukaryotic translation initiation factor 3 complex | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
X00437 | T cell receptor beta constant 1 | TRBC1 | 3_10 | 0.014933232 | decreased | 1.224125547565511 | 32794_g_at | --- | --- | 533994 | 28639 | --- |  | immune response | receptor activity | membrane | --- | ---
U05861 | aldo-keto reductase family 1, member [NAME] (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) /// aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) | AKR1C1 /// AKR1C2 | 8_10 | 0.004968019 | decreased | 3.018914335352237 | 32805_at | 600449 /// 600450 | ENSG00000187134 /// ENSG00000151632 | 498513 | 1645 /// 1646 | NM_001353 /// NM_001354 /// NM_205845 |  | xenobiotic metabolism /// lipid metabolism /// transport /// digestion /// steroid metabolism /// canalicular bile acid transport | aldo-keto reductase activity /// binding /// electron transporter activity /// bile acid transporter activity /// trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity /// binding /// electron transporter activity /// bile acid transporter activity /// oxidoreductase activity /// 3-alpha-hydroxysteroid dehydrogenase (A-specific) activity | cytoplasm | --- | ---
[NAME] | fibrillarin | FBL | 9_10 | 0.025674358 | decreased | 1.702469433217074 | 32843_s_at | 134795 | ENSG00000105202 | 299002 | 2091 | NM_001436 |  | rRNA processing | RNA binding | nucleus /// ribonucleoprotein complex | --- | ---
AC005192 | interferon-related developmental regulator 1 | IFRD1 | 10_11 | 0.008865098 | decreased | 1.8706323969387 | 32901_s_at | 603502 | ENSG00000006652 | 7879 | 3475 | NM_001007245 /// NM_001550 |  | [NAME] fate determination | binding | --- | Hypertrophy_model | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Hypertrophy_model/Hs_Hypertrophy_model.htm
AJ012214 | POU domain, class 2, transcription factor 3 | POU2F3 | 5_3 | 0.030306277 | increased | 2.607400450118718 | 32928_at | 607394 | ENSG00000137709 | 227115 | 25833 | NM_014352 |  | regulation of transcription from RNA polymerase II promoter /// epidermis development | transcription factor activity | nucleus | --- | ---
U84401 | smoothened homolog (Drosophila) | SMO | 8_10 | 0.029119086 | decreased | 2.041710522741591 | 32960_at | 601500 | ENSG00000128602 | 437846 | 6608 | NM_005631 |  | G-protein coupled receptor protein signaling pathway /// development | [NAME] coupled 7TM receptor activity /// G-protein coupled receptor activity /// protein binding | membrane fraction /// membrane /// integral to membrane | GPCRDB_Other | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Other/Hs_GPCRDB_Other.htm
X81479 | egf-like module containing, mucin-like, hormone receptor-like 1 | EMR1 | 5_3 | 0.000862624 | increased | 1.75521646281241 | 32964_at | 600493 | ENSG00000174837 | 2375 | 2015 | NM_001974 |  | cell adhesion /// signal transduction /// neuropeptide signaling pathway | receptor activity /// G-protein coupled receptor activity /// G-protein coupled receptor activity /// calcium ion binding | integral to plasma membrane /// membrane | GPCRDB_Class_B_Secretin-like | [NAME]
Y10148 | neurotensin receptor 2 | NTSR2 | 7_2 | 0.00500033 | increased | 1.987322240577482 | 33011_at | 605538 | ENSG00000169006 | 131138 | 23620 | NM_012344 |  | G-protein coupled receptor protein signaling pathway /// sensory perception | rhodopsin-like receptor activity /// receptor activity /// neurotensin receptor activity, G-protein coupled | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
AL049337 | TGF-betaIIR beta | --- | 8_10 | 0.012045005 | decreased | 1.95181742198216 | 33015_at | --- | --- | 434948 | --- | --- |  | --- | --- | --- | --- | ---
AF074015 | integrin, alpha 10 | ITGA10 | 5_2 | 0.009504469 | increased | 1.970298273106132 | 33082_at | 604042 | ENSG00000143127 | 158237 | 8515 | NM_003637 |  | cell-matrix adhesion /// integrin-mediated signaling pathway | magnesium ion binding /// receptor activity /// collagen binding | [NAME] /// integral to membrane | Integrin-mediated_cell_adhesion_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Integrin-mediated_cell_adhesion_KEGG/Hs_Integrin-mediated_cell_adhesion_KEGG.htm
AJ001366 | potassium voltage-gated channel, subfamily H (eag-related), member 1 | KCNH1 | 3_10 | 0.01979421 | decreased | 2.49200798793386 | 33087_s_at | 603305 | ENSG00000143473 | 527656 | 3756 | NM_002238 /// NM_172362 |  | two-component signal transduction system (phosphorelay) /// cation transport /// potassium ion transport /// myoblast fusion | two-component sensor molecule activity /// delayed rectifier potassium channel activity /// calmodulin binding | membrane fraction /// voltage-gated potassium channel complex /// membrane /// integral to membrane | --- | ---
D67031 | adducin 3 (gamma) | [NAME] | 8_10 | 0.020876508 | decreased | 1.576224633839115 | 33102_at | 601568 | ENSG00000148700 | 501012 | 120 | NM_001121 /// NM_016824 /// NM_019903 |  | --- | structural constituent of cytoskeleton /// calmodulin binding | cytoskeleton /// membrane | --- | ---
U37012 | cleavage and polyadenylation specific factor 1, 160kDa | CPSF1 | 4_11 | 0.018074337 | decreased | 2.599558303532112 | 33132_at | 606027 | [NAME] | 493202 | 29894 | NM_013291 |  | mRNA polyadenylylation /// mRNA cleavage | RNA binding /// mRNA 3'-UTR binding | nucleus /// mRNA cleavage and polyadenylation specificity factor complex | mRNA_processing_Reactome | [NAME]
AB011083 | adenylate cyclase 3 | ADCY3 | 4_9 | 0.020450537 | decreased | 1.539584066192512 | 33134_at | 600291 | ENSG00000138031 | 467898 | 109 | NM_004036 |  | cAMP biosynthesis /// intracellular signaling cascade /// perception of smell | magnesium ion binding /// adenylate cyclase activity /// calmodulin binding | plasma membrane /// integral to plasma membrane | G_Protein_Signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction /// Purine metabolism | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// [NAME] /// [NAME]
AF029893 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 | B3GNT6 | 8_10 | 0.017635517 | decreased | 1.088536709931906 | 33140_at | 605517 | ENSG00000174684 | 8526 | 11041 | NM_006876 |  | poly-N-acetyllactosamine biosynthesis | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity /// transferase activity, transferring glycosyl groups | Golgi apparatus /// integral to membrane /// integral to Golgi membrane | --- | ---
U81800 | solute carrier family 16 (monocarboxylic acid transporters), member 3 | SLC16A3 | 5_2 | 0.0282655 | increased | 1.822470176345955 | 33143_s_at | 603877 | ENSG00000141526 | 500761 | 9123 | NM_004207 |  | transport /// organic anion transport /// monocarboxylic acid transport | transporter activity /// symporter activity /// monocarboxylate porter activity | membrane fraction /// integral to plasma membrane | --- | ---
U61262 | neogenin homolog 1 (chicken) | NEO1 | 2_7 | 0.002688271 | decreased | 2.224694185760449 | 33169_at | 601907 | ENSG00000067141 | 388613 | 4756 | NM_002499 |  | protein amino acid phosphorylation /// cell motility /// cell adhesion /// cell-cell signaling /// development | vascular endothelial growth factor receptor activity /// protein binding /// ATP binding | plasma membrane /// integral to plasma membrane | --- | ---
AL046961 | hypothetical protein LOC339005 | LOC339005 | 1_3 | 0.020090682 | increased | 1.649823870132624 | 33186_i_at | --- | --- | 212670 | 339005 | XM_370838 |  | --- | --- | --- | --- | ---
U08316 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | RPS6KA3 | 9_11 | 0.01809642 | decreased | 1.89440599052581 | 33229_at | 300075 /// 303600 | [NAME] | 445387 | 6197 | NM_004586 |  | skeletal development /// protein amino acid phosphorylation /// signal transduction /// central nervous system development | protein serine/threonine kinase activity /// ATP binding /// transferase activity | --- | Ribosomal_Proteins | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Ribosomal_Proteins/Hs_Ribosomal_Proteins.htm
AA521481 | Transcribed locus | --- | 5_5 | 0.024550345 | increased | 1.830247990222128 | 33246_at | --- | --- | 552947 | --- | --- |  | --- | --- | --- | --- | ---
M81652 | semenogelin II | SEMG2 | 6_11 | 0.027535302 | decreased | 1.133633592046541 | 33259_at | 182141 | ENSG00000124157 | 537218 | 6407 | NM_003008 |  | sexual reproduction | structural molecule activity | extracellular space /// secretory granule | --- | ---
AB028996 | myotubularin related protein 2 | MTMR2 | 3_9 | 0.000964728 | decreased | 1.571525054930876 | 33277_at | 601382 /// 603557 | ENSG00000087053 | 181326 | 8898 | NM_016156 /// NM_201278 /// NM_201281 |  | protein amino acid dephosphorylation /// protein amino acid dephosphorylation /// phospholipid dephosphorylation | inositol or phosphatidylinositol phosphatase activity /// inositol or phosphatidylinositol phosphatase activity /// protein tyrosine phosphatase activity /// protein binding /// protein tyrosine/serine/threonine phosphatase activity /// hydrolase activity | nucleus /// cytoplasm | --- | ---
D88827 | zinc finger protein 263 | ZNF263 | 1_5 | 0.035082172 | increased | 1.563414396994201 | 33288_i_at | 604191 | ENSG00000006194 | 124553 | 10127 | NM_005741 |  | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// zinc ion binding | nucleus | --- | ---
AF009674 | axin 1 | [NAME] | 3_10 | 0.013357766 | decreased | 1.805861945771167 | 33319_at | 114550 /// 603816 | ENSG00000103126 | 512765 | 8312 | NM_003502 /// NM_181050 |  | apoptosis /// cell cycle /// frizzled signaling pathway /// development /// oocyte axis determination /// negative regulation of cell cycle | signal transducer activity /// signal transducer activity | intracellular /// cytoplasm | Wnt_signaling | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm
AB005754 | polymerase (DNA directed) sigma | POLS | 9_11 | 0.011855428 | decreased | 1.781347554848984 | 33380_at | 605198 | ENSG00000112941 | 481542 | 11044 | NM_006999 |  | DNA replication and chromosome cycle /// cytokinesis /// DNA repair /// sister chromatid cohesion /// mitosis | DNA binding /// DNA-directed DNA polymerase activity /// transferase activity | nucleus | --- | ---
HG2987-HT3136 | --- | --- | 1_5 | 0.002855992 | increased | 2.018341657674863 | 334_s_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
X57398 | NODAL modulator 1 /// NODAL modulator 2 /// NODAL modulator 3 | [NAME] /// NOMO2 /// NOMO3 | 9_11 | 0.034756602 | decreased | 1.94597082963452 | 33414_at | 609157 /// 609158 /// 609159 | ENSG00000103512 /// ENSG00000185164 /// ENSG00000103226 | 209113 | 23420 /// 283820 /// 408050 | NM_001004060 /// NM_001004067 /// NM_014287 /// NM_173614 |  | aromatic compound metabolism | catalytic activity /// ferric iron binding | --- | --- | ---
AF052155 | SEC13-like 1 (S. cerevisiae) | SEC13L1 | 9_11 | 0.022605178 | decreased | 1.77311827922018 | 33423_g_at | 600152 | ENSG00000157020 | 166924 | 6396 | NM_030673 /// NM_183352 |  | intracellular protein transport | --- | --- | --- | ---
AB000095 | serine protease inhibitor, Kunitz type 1 | SPINT1 | 5_2 | 0.007627333 | increased | 1.807066472479703 | 33448_at | 605123 | ENSG00000166145 | 233950 | 6692 | NM_003710 /// NM_181642 |  | --- | serine-type endopeptidase inhibitor activity | extracellular region /// membrane fraction | --- | ---
AF052177 | glutamate receptor interacting protein 2 | GRIP2 | 1_1 | 0.007461502 | increased | 1.884939548636782 | 33470_at | --- | ENSG00000144596 | 517819 | 80852 | XM_042936 |  | --- | protein binding | membrane | --- | ---
M13232 | coagulation factor VII (serum prothrombin conversion accelerator) | F7 | 7_3 | 0.026460246 | increased | 1.421821645126365 | 33520_at | 227500 | ENSG00000057593 | 36989 | 2155 | NM_000131 /// NM_019616 |  | proteolysis and peptidolysis /// blood coagulation | coagulation factor VIIa activity /// chymotrypsin activity /// trypsin activity /// calcium ion binding | extracellular region | Blood_Clotting_Cascade | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Blood_Clotting_Cascade/Hs_Blood_Clotting_Cascade.htm
[NAME] | potassium inwardly-rectifying channel, subfamily J, member 3 | KCNJ3 | 8_10 | 0.032167176 | decreased | 1.219257668126784 | 33527_at | 601534 | ENSG00000162989 | 199776 | 3760 | NM_002239 |  | ion transport /// potassium ion transport | voltage-gated ion channel activity /// potassium channel activity /// G-protein activated inward rectifier potassium channel activity | voltage-gated potassium channel complex /// membrane /// integral to membrane | G_Protein_Signaling /// Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
AI435898 | zinc finger protein 46 (KUP) | ZNF46 | 8_10 | 0.007099596 | decreased | 1.448104681789906 | 33617_s_at | 194541 | ENSG00000089775 | 164347 | 7597 | NM_006977 |  | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// protein binding /// zinc ion binding | nucleus | --- | ---
AF023612 | thioredoxin-like 4A | TXNL4A | 9_11 | 0.011902652 | decreased | 1.178943771658141 | 33631_at | --- | ENSG00000141759 | 465498 | 10907 | NM_006701 |  | spliceosome assembly /// cytokinesis /// electron transport /// cell cycle /// mitosis /// mitosis | electron transporter activity /// RNA splicing factor activity, transesterification mechanism | spliceosome complex /// spliceosome complex | mRNA_processing_Reactome | [NAME]
U17986 | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | SLC6A8 | 3_10 | 0.001440991 | decreased | 1.775623204072663 | 33642_s_at | 300036 /// 300352 /// 300397 | ENSG00000130821 | 540696 | 6535 | NM_005629 |  | neurotransmitter uptake /// ion transport /// sodium ion transport /// neurotransmitter transport /// muscle contraction | creatine:sodium symporter activity /// neurotransmitter:sodium symporter activity /// symporter activity | integral to plasma membrane /// membrane | --- | ---
W28800 | hypothetical protein LOC157697 | LOC157697 | 2_10 | 0.021613112 | decreased | 2.481281418475019 | 33648_at | --- | ENSG00000104714 | 128130 | 157697 | NM_207332 |  | --- | --- | --- | --- | ---
AB028975 | KIAA1052 protein | Cep164 | 8_10 | 0.033489355 | decreased | 1.492015009310581 | 33698_at | --- | ENSG00000110274 | 504009 | 22897 | NM_014956 |  | --- | --- | --- | --- | ---
AB011111 | chromosome 21 open reading frame 108 | C21orf108 | 1_3 | 0.016333698 | increased | 1.047312515484306 | 33704_at | 608865 | --- | 473611 | 9875 | --- |  | --- | nucleic acid binding | nucleolus | --- | ---
V01510 | [NAME] (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin) | POMC | 2_10 | 0.009854139 | decreased | 1.197075743360653 | 33711_at | 176830 | ENSG00000115138 | 1897 | 5443 | NM_000939 |  | generation of precursor metabolites and energy /// signal transduction /// neuropeptide signaling pathway /// cell-cell signaling | hormone activity | extracellular region /// soluble fraction | --- | ---
M31606 | phosphorylase kinase, gamma 2 (testis) | PHKG2 | 8_10 | 0.029330883 | decreased | 1.230635936430623 | 33745_at | 172471 | [NAME] | 196177 | 5261 | NM_000294 |  | carbohydrate metabolism /// glycogen biosynthesis /// generation of precursor metabolites and energy /// protein amino acid phosphorylation /// protein amino acid phosphorylation | protein kinase activity /// protein serine/threonine kinase activity /// phosphorylase kinase activity /// phosphorylase kinase activity /// calmodulin binding /// ATP binding /// ATP binding /// transferase activity | phosphorylase kinase complex /// phosphorylase kinase complex | Glycogen_Metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Glycogen_Metabolism/Hs_Glycogen_Metabolism.htm
AB014566 | dishevelled associated activator of morphogenesis 1 | DAAM1 | 9_11 | 0.000105371 | decreased | 1.565457831048814 | 33753_at | 606626 | ENSG00000100592 | 19156 | 23002 | NM_014992 |  | cell organization and biogenesis /// actin cytoskeleton organization and biogenesis | [NAME] binding /// Rho GTPase binding | --- | --- | ---
S63912 | heterogeneous nuclear ribonucleoprotein A3 | HNRPA3 | 9_11 | 0.015699787 | decreased | 1.835288096383632 | 33817_at | 605372 | ENSG00000170144 | 516539 | 220988 | NM_194247 |  | --- | nucleotide binding /// RNA binding | nucleus /// ribonucleoprotein complex | mRNA_processing_Reactome | [NAME]
X13794 | lactate dehydrogenase B | LDHB | 9_11 | 0.024980023 | decreased | 1.550694441827393 | 33819_at | 150100 | ENSG00000111716 | 446149 | 3945 | NM_002300 |  | tricarboxylic acid cycle intermediate metabolism /// anaerobic glycolysis | L-lactate dehydrogenase activity /// oxidoreductase activity | cytoplasm | Glycolysis_and_Gluconeogenesis /// Glycolysis / Gluconeogenesis /// Cysteine metabolism /// Pyruvate metabolism /// Propanoate metabolism | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00010+1.1.1.27 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00272+1.1.1.27 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00620+1.1.1.27 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00640+1.1.1.27
AL049783 | phosphonoformate immuno-associated protein 5 | PFAAP5 | 10_7 | 0.004769649 | decreased | 1.727066227286042 | 33827_at | --- | ENSG00000139617 | 507680 | 10443 | NM_014887 |  | --- | --- | --- | --- | ---
AA448478 | Interferon, alpha-inducible protein (clone IFI-6-16) | G1P3 | 10_10 | 0.032937139 | decreased | 1.216256077278986 | 33832_at | 147572 | ENSG00000126709 | 523847 | 2537 | NM_002038 /// NM_022872 /// NM_022873 |  | immune response /// response to pest, pathogen or parasite | --- | integral to membrane | --- | ---
M77142 | TIA1 cytotoxic granule-associated RNA binding protein | TIA1 | 6_10 | 0.029581181 | decreased | 1.339657218635285 | 33852_at | 603518 | ENSG00000116001 | 516075 | 7072 | NM_022037 /// NM_022173 |  | apoptosis /// induction of apoptosis | nucleotide binding /// [NAME] binding /// poly(A) binding | --- | --- | ---
N25122 | NSFL1 (p97) cofactor (p47) | NSFL1C | 4_11 | 0.020933373 | decreased | 2.09641810880258 | 33857_at | 606610 | ENSG00000088833 | 12865 | 55968 | NM_016143 /// NM_018839 /// NM_182483 |  | --- | lipid binding | nucleus /// Golgi apparatus | --- | ---
AL080218 | signal transducer and activator of transcription 5B | STAT5B | 4_11 | 0.027355681 | decreased | 2.629509014619384 | 33869_at | 245590 /// 604260 | ENSG00000173757 | 132864 | 6777 | [NAME] |  | transcription /// regulation of transcription from RNA polymerase II promoter /// intracellular signaling cascade /// JAK-STAT cascade | transcription factor activity /// signal transducer activity /// calcium ion binding | nucleus | --- | ---
AB028990 | [NAME] | LYRIC | 9_11 | 0.008955381 | decreased | 1.693770275570209 | 33877_s_at | --- | ENSG00000147649 | 377155 | 92140 | NM_178812 |  | --- | --- | nucleus /// integral to membrane | --- | ---
AF051782 | diaphanous homolog 1 (Drosophila) | DIAPH1 | 5_2 | 0.00586531 | increased | 1.747724177201931 | 33920_at | 124900 /// 602121 | ENSG00000131504 | 529451 | 1729 | NM_005219 |  | perception of sound /// cell organization and biogenesis /// actin cytoskeleton organization and biogenesis | [NAME] binding /// receptor binding /// profilin binding /// Rho GTPase binding | --- | G13_Signaling_Pathway | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G13_Signaling_Pathway/Hs_G13_Signaling_Pathway.htm
AB018340 | [NAME]/sentrin specific protease 6 | SENP6 | 8_11 | 0.004412142 | decreased | 2.133642193279449 | 33934_at | 605003 | ENSG00000112701 | 485784 | 26054 | NM_015571 |  | proteolysis and peptidolysis /// ubiquitin cycle | cysteine-type peptidase activity | --- | --- | ---
X91906 | chloride channel 5 (nephrolithiasis 2, X-linked, Dent disease) | CLCN5 | 5_5 | 0.00441565 | increased | 2.352534671095206 | 34024_at | 300008 /// 300009 /// 310468 | ENSG00000171365 | 535985 | 1184 | NM_000084 |  | ion transport /// chloride transport /// excretion | voltage-gated chloride channel activity | integral to plasma membrane /// membrane | --- | ---
AL109691 | Phosphodiesterase 8A | PDE8A | 10_10 | 0.01744988 | decreased | 1.339553805728988 | 34142_at | 602972 | ENSG00000073417 | 9333 | 5151 | NM_002605 /// NM_173454 /// NM_173455 /// NM_173456 /// NM_173457 |  | signal transduction /// cyclic nucleotide metabolism | magnesium ion binding /// 3',5'-cyclic-nucleotide phosphodiesterase activity /// signal transducer activity /// hydrolase activity /// manganese ion binding | --- | G_Protein_Signaling /// Purine metabolism | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+3.1.4.17
W22541 | poly(rC) binding protein 4 | PCBP4 | 4_11 | 0.032362059 | decreased | 2.355068750623617 | 34185_at | 608503 | ENSG00000090097 | 20930 | 57060 | NM_020418 /// NM_033008 /// NM_033009 /// NM_033010 |  | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest /// cell cycle arrest /// DNA damage response, signal transduction resulting in induction of apoptosis /// mRNA metabolism | nucleic acid binding /// DNA binding /// [NAME] binding /// RNA binding | nucleus /// ribonucleoprotein complex | --- | ---
AA478904 | Kruppel-like factor 7 (ubiquitous) | KLF7 | 4_11 | 0.008770323 | decreased | 1.659494368354534 | 34216_at | 604865 | ENSG00000118263 | 471221 | 8609 | NM_003709 |  | transcription /// regulation of transcription from RNA polymerase II promoter | transcription factor activity /// transcription coactivator activity /// zinc ion binding | nucleus | --- | ---
AF084535 | epilepsy, progressive myoclonus type 2A, [NAME] disease (laforin) | EPM2A | 9_11 | 0.032808221 | decreased | 1.948011239701788 | 34249_at | 254780 /// 607566 | ENSG00000112425 | 486696 | 7957 | NM_005670 |  | carbohydrate metabolism /// glycogen metabolism /// regulation of translation /// protein amino acid dephosphorylation | protein tyrosine phosphatase activity /// protein tyrosine/serine/threonine phosphatase activity /// hydrolase activity | nucleus /// endoplasmic reticulum /// polysome | --- | ---
AB029033 | IQ motif and Sec7 domain 3 | IQSEC3 | 8_10 | 0.030546516 | decreased | 1.367395603881608 | 34250_at | --- | --- | 352612 | 440073 | XM_370667 /// XM_495902 |  | --- | --- | --- | --- | ---
Y15909 | diaphanous homolog 2 (Drosophila) | DIAPH2 | 8_10 | 0.028407357 | decreased | 1.249542638451531 | 34262_at | 300108 /// 300511 | ENSG00000147202 | 226483 | 1730 | NM_006729 /// NM_007309 |  | cytokinesis /// female gamete generation /// cell organization and biogenesis /// actin cytoskeleton organization and biogenesis /// cell differentiation | [NAME] binding /// receptor binding /// Rho GTPase binding | membrane | DNA_replication_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_DNA_replication_Reactome/Hs_DNA_replication_Reactome.htm
AB026894 | RUN and SH3 domain containing 1 | [NAME] | 9_11 | 0.021652797 | decreased | 1.831788789719277 | 34264_at | --- | ENSG00000160753 | 226499 | 23623 | NM_014328 |  | --- | SH3/SH2 adaptor activity | nucleus | --- | ---
AB023197 | KIAA0980 protein | KIAA0980 | 7_3 | 0.006103898 | increased | 1.298524372657161 | 34276_at | --- | ENSG00000101004 | 472347 | 22981 | NM_025176 |  | --- | calcium ion binding | --- | --- | ---
L18960 | eukaryotic translation initiation factor 1A, X-linked | EIF1AX | 8_10 | 0.00699522 | decreased | 1.803608288449531 | 34278_at | 300186 | ENSG00000173674 | 522590 | 1964 | NM_001412 |  | protein biosynthesis /// translational initiation /// translational initiation | RNA binding /// translation initiation factor activity | eukaryotic translation initiation factor 4F complex | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
AJ132917 | methyl CpG binding protein 2 ([NAME] syndrome) | MECP2 | 9_11 | 0.035302109 | decreased | 1.630541319182006 | 34355_at | 105830 /// 300005 /// 300055 /// 300279 /// 300425 /// 300458 /// 312750 | ENSG00000169057 | 200716 | 4204 | NM_004992 |  | negative regulation of transcription from RNA polymerase II promoter /// transcription /// regulation of transcription, DNA-dependent | DNA binding /// transcription corepressor activity | nucleus | --- | ---
Z97054 | --- | --- | 6_10 | 0.012713515 | decreased | 1.010165007617201 | 34373_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
U47927 | ubiquitin specific protease 5 (isopeptidase T) | USP5 | 6_11 | 0.013009543 | decreased | 1.515404743939821 | 34405_at | 601447 | ENSG00000111667 | 3759 | 8078 | NM_003481 |  | ubiquitin-dependent protein catabolism /// ubiquitin cycle | cysteine-type endopeptidase activity /// ubiquitin-specific protease 5 activity | proteasome complex (sensu [NAME]) /// lysosome | G_Protein_Signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
U49260 | mevalonate (diphospho) decarboxylase | MVD | 8_10 | 0.002654966 | decreased | 2.002354023443915 | 34410_at | 603236 | ENSG00000167508 | 252457 | 4597 | NM_002461 |  | cholesterol biosynthesis /// isoprenoid biosynthesis /// phosphorylation | diphosphomevalonate decarboxylase activity /// ATP binding /// kinase activity /// lyase activity | --- | Cholesterol_Biosynthesis /// Biosynthesis of steroids | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00100+4.1.1.33
[NAME] | family with sequence similarity 5, member C | FAM5C | 3_10 | 0.018986211 | decreased | 2.381200007958222 | 34442_at | --- | ENSG00000162670 | 65765 | 339479 | NM_199051 |  | --- | --- | --- | --- | ---
AL109725 | alpha-kinase 3 | ALPK3 | 7_3 | 0.02353704 | increased | 1.509354224487489 | 34505_at | --- | ENSG00000136383 | 459183 | 57538 | NM_020778 |  | protein amino acid phosphorylation /// heart development | protein serine/threonine kinase activity /// ATP binding /// kinase activity | nucleus | --- | ---
S49816 | thyroid stimulating hormone receptor | TSHR | 6_10 | 0.026618181 | decreased | 2.602801486949621 | 34515_g_at | 275000 /// 275200 /// 603372 | ENSG00000165409 | 160411 | 7253 | NM_000369 |  | signal transduction /// G-protein signaling, coupled to cyclic nucleotide second messenger /// cell-cell signaling /// positive regulation of cell proliferation | receptor activity /// thyroid-stimulating hormone receptor activity | integral to plasma membrane | GPCRDB_Other /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Other/Hs_GPCRDB_Other.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
AJ005371 | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | GAPDS | 1_5 | 0.022208609 | increased | 1.70222923931797 | 34542_at | 609169 | ENSG00000105679 | 248017 | 26330 | NM_014364 |  | glucose metabolism /// glycolysis | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity /// oxidoreductase activity /// NAD binding | --- | Glycolysis_and_Gluconeogenesis | [NAME]
AF070587 | KIAA1509 | KIAA1509 | 1_5 | 0.008285289 | increased | 1.467020312179564 | 34545_at | --- | --- | 525536 | 440193 | XM_029353 /// XM_496003 |  | --- | --- | --- | --- | ---
M61733 | erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) | EPB41 | 2_10 | 0.003678564 | decreased | 1.963818254990262 | 34581_s_at | 130500 | ENSG00000159023 | 175437 | 2035 | NM_004437 /// NM_203342 /// NM_203343 |  | circulation /// cortical actin cytoskeleton organization and biogenesis | [NAME] binding /// structural constituent of cytoskeleton /// binding | nucleus /// cytoplasm /// cytoskeleton /// plasma membrane /// spectrin | --- | ---
D78367 | keratin 12 (Meesmann corneal dystrophy) | [NAME] | 1_5 | 0.013130139 | increased | 1.300797707792123 | 34615_at | 122100 /// 601687 | ENSG00000187242 | 66739 | 3859 | NM_000223 |  | visual perception | structural molecule activity | intermediate filament | --- | ---
AF015812 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 | DDX5 | 4_11 | 0.008066008 | decreased | 1.91543686227404 | 34647_at | 180630 | ENSG00000108654 | 279806 | 1655 | NM_004396 |  | cell growth | RNA binding /// [NAME] helicase activity /// ATP binding /// ATP-dependent helicase activity /// hydrolase activity | nucleus | --- | ---
AB020653 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | [NAME] | 8_10 | 0.022956475 | decreased | 1.491669720886367 | 34748_at | --- | ENSG00000152689 | 143674 | 25780 | NM_170672 |  | MAPKKK cascade /// small GTPase mediated signal transduction | signal transducer activity /// guanyl-nucleotide exchange factor activity /// calcium ion binding /// protein binding /// diacylglycerol binding /// [NAME] activator activity | integral to plasma membrane | --- | ---
AJ236876 | poly (ADP-ribose) polymerase family, member 2 | PARP2 | 10_10 | 0.008044228 | decreased | 1.336262672968139 | 34756_g_at | 607725 | ENSG00000129484 | 409412 | 10038 | NM_005484 |  | DNA repair /// protein amino acid ADP-ribosylation | DNA binding /// NAD+ ADP-ribosyltransferase activity /// transferase activity, transferring glycosyl groups | nucleus | --- | ---
W27541 | CDC42 effector protein (Rho GTPase binding) 4 | CDC42EP4 | 6_10 | 0.033190342 | decreased | 2.798006514052715 | 34776_at | 605468 | ENSG00000179604 | 3903 | 23580 | NM_012121 |  | cellular morphogenesis | --- | cytoskeleton | --- | ---
U58334 | tumor protein p53 binding protein, 2 | TP53BP2 | 8_10 | 0.030577936 | decreased | 1.415580250351503 | 34822_at | 602143 | ENSG00000143514 | 523968 | 7159 | NM_005426 |  | regulation of cell cycle /// apoptosis /// signal transduction | SH3/SH2 adaptor activity | cytoplasm | --- | ---
U41303 | small nuclear ribonucleoprotein polypeptide N /// SNRPN upstream reading frame | SNRPN /// SNURF | 9_11 | 0.023862067 | decreased | 1.690473190917879 | 34842_at | 176270 /// 182279 | ENSG00000128739 | 525700 | 6638 /// 8926 | /// NM_003097 /// NM_005678 /// NM_022804 /// NM_022805 /// NM_022806 /// NM_022807 /// NM_022808 |  | mRNA processing | RNA binding | nucleus /// small nucleolar ribonucleoprotein complex /// nucleus | mRNA_processing_Reactome | [NAME]
L29376 | MHC class I mRNA fragment 3.8-1 | 3.8-1 | 8_10 | 0.00660627 | decreased | 1.609417776582764 | 34934_at | --- | --- | 132807 | 352961 | --- |  | --- | --- | --- | --- | ---
AJ223183 | immunoglobulin superfamily, member 6 | IGSF6 | 7_3 | 0.011178133 | increased | 1.573630236574766 | 34946_at | 606222 | ENSG00000140749 | 530902 | 10261 | NM_005849 |  | immune response /// cell surface receptor linked signal transduction | [NAME] receptor activity | integral to plasma membrane | --- | ---
X95826 | Dombrock blood group | DO | 1_5 | 9.27e-06 | increased | 1.931592015395524 | 34952_at | 110600 | ENSG00000111339 | 13776 | 420 | NM_021071 |  | protein amino acid ADP-ribosylation /// arginine metabolism | [NAME] ADP-ribosyltransferase activity /// transferase activity, transferring glycosyl groups | membrane | --- | ---
M15059 | Fc fragment of IgE, low affinity II, receptor for (CD23A) | FCER2 | 9_11 | 0.023065066 | decreased | 1.443240190243142 | 34959_at | 151445 | ENSG00000104921 | 465778 | 2208 | NM_002002 |  | --- | receptor activity /// receptor signaling protein activity /// integrin binding /// sugar binding /// IgE binding | integral to plasma membrane | --- | ---
AB022660 | SET binding protein 1 | SETBP1 | 4_11 | 0.009000714 | decreased | 2.72745635348335 | 34990_at | --- | ENSG00000152217 | 435458 | 26040 | NM_015559 |  | --- | DNA binding | nucleus | --- | ---
L76380 | calcitonin receptor-like | CALCRL | 1_3 | 0.021092821 | increased | 1.708422749097102 | 34995_at | 114190 | ENSG00000064989 | 470882 | 10203 | NM_005795 |  | signal transduction /// G-protein signaling, coupled to cyclic nucleotide second messenger | receptor activity /// G-protein coupled receptor activity /// calcitonin receptor activity | integral to plasma membrane /// membrane | GPCRDB_Class_B_Secretin-like | [NAME]
AL050012 | golgi autoantigen, golgin subfamily a, 1 | GOLGA1 | 8_10 | 0.009457357 | decreased | 1.21253160564584 | 35058_at | 602502 | ENSG00000136935 | 133469 | 2800 | NM_002077 |  | --- | --- | --- | --- | ---
AI925946 | angiogenic factor with G patch and FHA domains 1 | AGGF1 | 7_3 | 0.011722438 | increased | 1.762554810001103 | 35067_at | 149000 /// 608464 | ENSG00000164252 | 213393 | 55109 | NM_018046 |  | two-component signal transduction system (phosphorelay) /// angiogenesis /// cell differentiation | two-component sensor molecule activity /// nucleic acid binding | intracellular | --- | ---
L32164 | zinc finger protein 167 | ZNF167 | 1_6 | 0.019632115 | increased | 2.110196014356543 | 35102_at | --- | ENSG00000196345 | 529512 | 55888 | NM_018651 /// NM_025169 |  | transcription /// regulation of transcription, DNA-dependent | nucleic acid binding /// DNA binding /// transcription factor activity /// zinc ion binding | nucleus | --- | ---
X15722 | glutathione reductase | GSR | 10_10 | 0.03338003 | decreased | 2.266891219067566 | 35130_at | 138300 | ENSG00000104687 | 271510 | 2936 | NM_000637 |  | electron transport /// glutathione metabolism /// response to pest, pathogen or parasite | glutathione-disulfide reductase activity /// disulfide oxidoreductase activity /// FAD binding | mitochondrion | --- | ---
X60592 | CD40 antigen (TNF receptor superfamily member 5) | CD40 | 7_3 | 0.017421636 | increased | 1.778292585500882 | 35150_at | 109535 /// 606843 | ENSG00000101017 | 472860 | 958 | NM_001250 /// NM_152854 |  | protein complex assembly /// apoptosis /// inflammatory response /// immune response /// signal transduction /// development /// antimicrobial humoral response (sensu Vertebrata) /// platelet activation /// B-cell proliferation /// positive regulation of I-kappaB kinase/NF-kappaB cascade | [NAME] receptor activity | plasma membrane /// integral to plasma membrane /// membrane | [NAME] /// Inflammatory_Response_Pathway | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Inflammatory_Response_Pathway/Hs_Inflammatory_Response_Pathway.htm
AJ001016 | receptor (calcitonin) activity modifying protein 3 | RAMP3 | 1_6 | 0.021279086 | increased | 1.556545959052908 | 35152_at | 605155 | ENSG00000122679 | 25691 | 10268 | NM_005856 |  | intracellular protein transport /// receptor mediated endocytosis /// cell surface receptor linked signal transduction /// regulation of G-protein coupled receptor protein signaling pathway | receptor activity /// protein transporter activity | lysosome /// plasma membrane /// integral to plasma membrane | Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
AB020667 | U-box domain containing 5 | UBOX5 | 8_10 | 0.034894175 | decreased | 2.388553038327436 | 35161_at | --- | ENSG00000185019 | 129448 | 22888 | NM_014948 /// NM_199415 |  | protein ubiquitination | ubiquitin-protein ligase activity /// zinc ion binding | ubiquitin ligase complex /// nucleus | --- | ---
AB018336 | FERM, [NAME] and pleckstrin domain protein 2 | FARP2 | 8_11 | 0.021207031 | decreased | 1.353886443667559 | 35188_at | --- | ENSG00000006607 | 552580 | 9855 | NM_014808 |  | --- | cytoskeletal protein binding | cytoplasm /// cytoskeleton /// membrane | --- | ---
AF007216 | solute carrier family 4, sodium bicarbonate cotransporter, member 4 | SLC4A4 | 7_3 | 0.016394856 | increased | 1.933269849872292 | 35285_at | 603345 /// 604278 | ENSG00000080493 | 5462 | 8671 | NM_003759 |  | transport /// anion transport | inorganic anion exchanger activity /// sodium:bicarbonate symporter activity | integral to plasma membrane /// membrane /// integral to membrane | --- | ---
M25077 | Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro) | SSA2 | 9_11 | 0.008334727 | decreased | 2.521832019968509 | 35295_g_at | 600063 | ENSG00000116747 | 288178 | 6738 | NM_004600 |  | transcription from RNA polymerase III promoter | RNA binding | ribonucleoprotein complex | --- | ---
U96876 | insulin induced gene 1 | INSIG1 | 5_5 | 0.007252544 | increased | 1.532211848367207 | 35303_at | 602055 | [NAME] | 520819 | 3638 | NM_005542 /// NM_198336 /// NM_198337 |  | metabolism /// cell proliferation | --- | integral to membrane | --- | ---
U54559 | eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa | EIF3S3 | 3_10 | 0.012504183 | decreased | 1.608977958460059 | 35327_at | 603912 | ENSG00000147677 | 492599 | 8667 | NM_003756 |  | protein biosynthesis /// regulation of translational initiation | translation initiation factor activity | eukaryotic translation initiation factor 3 complex | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
X04714 | apolipoprotein B (including Ag(x) antigen) | APOB | 8_10 | 0.007208391 | decreased | 1.38315206482455 | 35332_at | 107730 /// 144010 | ENSG00000084674 | 120759 | 338 | NM_000384 |  | lipid metabolism /// lipid transport /// signal transduction /// circulation /// steroid metabolism /// cholesterol metabolism | receptor binding /// lipid transporter activity /// heparin binding | extracellular region /// soluble fraction /// endoplasmic reticulum /// microsome | --- | ---
U50939 | amyloid beta precursor protein binding protein 1, 59kDa | APPBP1 | 9_11 | 0.026720123 | decreased | 2.07727508508377 | 35364_at | 603385 | ENSG00000159593 | 460978 | 8883 | NM_003905 |  | ubiquitin cycle /// apoptosis /// cell cycle /// signal transduction | ligase activity | cytoplasm | --- | ---
AB023154 | deltex 4 homolog (Drosophila) | DTX4 | 5_2 | 0.03477541 | increased | 1.434495656082991 | 35369_at | --- | ENSG00000110042 | 523696 | 23220 | XM_166213 |  | protein ubiquitination | ubiquitin-protein ligase activity /// zinc ion binding | ubiquitin ligase complex | [NAME] | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm
AB009671 | a disintegrin and metalloproteinase domain 22 | ADAM22 | 1_3 | 0.00935476 | increased | 2.185529207060586 | 35392_g_at | 603709 | ENSG00000008277 | 256398 | 53616 | NM_004194 /// NM_016351 /// NM_021721 /// NM_021722 /// NM_021723 |  | proteolysis and peptidolysis /// negative regulation of cell adhesion /// central nervous system development | metalloendopeptidase activity /// integrin binding | integral to plasma membrane | --- | ---
AB021225 | matrix metalloproteinase 17 (membrane-inserted) | [NAME] | 10_10 | 0.029963373 | decreased | 1.611945416858802 | 35401_s_at | 602285 | ENSG00000198598 | 159581 | 4326 | NM_016155 |  | proteolysis and peptidolysis | metalloendopeptidase activity /// enzyme activator activity /// zinc ion binding | extracellular matrix (sensu Metazoa) /// integral to plasma membrane /// membrane | Matrix_Metalloproteinases | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Matrix_Metalloproteinases/Hs_Matrix_Metalloproteinases.htm
M60284 | [NAME] 2 | TACR2 | 6_11 | 0.02072061 | decreased | 1.965833330758724 | 35404_at | 162321 | ENSG00000075073 | 88372 | 6865 | NM_001057 |  | muscle contraction /// signal transduction /// tachykinin signaling pathway /// excretion | rhodopsin-like receptor activity /// receptor activity /// tachykinin receptor activity | plasma membrane /// integral to plasma membrane | Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
X16281 | zinc finger protein 44 (KOX 7) | ZNF44 | 10_10 | 0.018550516 | decreased | 0.9844987565218741 | 35409_r_at | 194542 | ENSG00000197857 | 24120 | 51710 | NM_016264 |  | transcription /// regulation of transcription, DNA-dependent | nucleic acid binding /// DNA binding /// zinc ion binding | intracellular /// nucleus | --- | ---
U77914 | jagged 1 (Alagille syndrome) | JAG1 | 9_11 | 0.011491976 | decreased | 1.655861592979678 | 35414_s_at | 118450 /// 187500 /// 601920 | ENSG00000101384 | 224012 | 182 | NM_000214 |  | angiogenesis /// cell fate determination /// cell communication /// Notch signaling pathway /// development /// neurogenesis /// hemopoiesis /// [NAME] differentiation /// regulation of cell migration /// regulation of cell proliferation /// myoblast differentiation /// endothelial cell differentiation | Notch binding /// structural molecule activity /// calcium ion binding /// calcium ion binding /// growth factor activity | extracellular region /// integral to plasma membrane /// membrane | --- | ---
U78082 | mediator of RNA polymerase II transcription, subunit 6 homolog (yeast) | MED6 | 3_10 | 0.000367787 | decreased | 1.724697583303025 | 35430_at | 602984 | ENSG00000133997 | 497353 | 10001 | NM_005466 |  | regulation of transcription from RNA polymerase II promoter | RNA polymerase II transcription factor activity /// receptor activity | mediator complex /// nucleus | --- | ---
AF038181 | Adenomatosis polyposis coli | APC | 6_10 | 0.023616805 | decreased | 1.53028709092722 | 35433_s_at | 135290 /// 137215 /// 175100 /// 276300 | ENSG00000134982 | 158932 | 324 | NM_000038 |  | protein complex assembly /// cell adhesion /// signal transduction /// Wnt receptor signaling pathway /// negative regulation of cell cycle | beta-catenin binding /// microtubule binding | --- | Wnt_signaling | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm
[NAME] | cocaine- and amphetamine-regulated transcript | CART | 3_10 | 0.004328764 | decreased | 2.116899937540183 | 35457_at | 602606 | ENSG00000164326 | 1707 | 9607 | NM_004291 |  | signal transduction /// neuropeptide signaling pathway /// cell-cell signaling /// synaptic transmission | --- | extracellular space | --- | ---
L78267 | Prader-Willi/Angelman syndrome-5 | PAR5 | 1_3 | 0.002637953 | increased | 2.87361376960839 | 35490_at | 600162 | --- | --- | 8123 | --- |  | --- | --- | --- | --- | ---
AI806113 | chromosome X open reading frame 27 | CXorf27 | 3_10 | 0.003940663 | decreased | 2.403764921858887 | 35501_at | --- | ENSG00000187516 | 122959 | 25763 | XM_048235 |  | --- | --- | --- | --- | ---
AI701514 | claudin 9 | CLDN9 | 7_3 | 0.011994763 | increased | 1.551572531123776 | 35520_at | --- | ENSG00000178709 | 296949 | 9080 | NM_020982 |  | calcium-independent cell-cell adhesion | structural molecule activity /// protein self binding | tight junction /// membrane /// integral to membrane | --- | ---
AF040710 | hyaluronoglucosaminidase 3 | HYAL3 | 10_10 | 0.019240809 | decreased | 1.266831355191588 | 35540_at | 604038 | [NAME] | 129910 | 8372 | NM_003549 |  | carbohydrate metabolism | hyalurononglucosaminidase activity /// hyalurononglucosaminidase activity | --- | --- | ---
AB014524 | SLAC2-B | SLAC2-B | 6_10 | 0.023528408 | decreased | 2.318380490467958 | 35579_at | --- | ENSG00000110723 | 269591 | 23086 | NM_015065 |  | intracellular protein transport | protein binding /// Rab GTPase binding | --- | --- | ---
AJ006216 | calcium channel, voltage-dependent, alpha 1F subunit | CACNA1F | 8_10 | 0.030146112 | decreased | 1.376863881384632 | 35584_s_at | 300071 /// 300110 | ENSG00000102001 | 139263 | 778 | NM_005183 |  | cation transport /// calcium ion transport /// synaptic transmission /// sensory perception /// visual perception | voltage-gated calcium channel activity /// calcium ion binding | voltage-gated calcium channel complex /// membrane /// integral to membrane | --- | ---
L77213 | phosphomevalonate kinase | PMVK | 2_11 | 0.035268947 | decreased | 2.410283381425588 | 35621_at | 607622 | ENSG00000163344 | 30954 | 10654 | NM_006556 |  | protein amino acid phosphorylation /// lipid metabolism /// cholesterol biosynthesis | phosphomevalonate kinase activity /// transferase activity | cytoplasm /// peroxisome | Cholesterol_Biosynthesis | [NAME]
AL050148 | Sorting nexin 1 | [NAME] | 9_11 | 0.005538942 | decreased | 1.535239217016174 | 35645_at | 601272 | ENSG00000028528 | 188634 | 6642 | NM_003099 /// NM_148955 /// NM_152826 |  | intracellular protein transport /// endocytosis /// intracellular signaling cascade | protein transporter activity | Golgi apparatus | --- | ---
AI133727 | zinc finger CCCH type, antiviral 1 | ZC3HAV1 | 3_10 | 0.000111389 | decreased | 2.010716553614114 | 35682_at | 607312 | ENSG00000105939 | 133512 | 56829 | NM_020119 /// NM_024625 |  | protein amino acid ADP-ribosylation | nucleic acid binding /// NAD+ ADP-ribosyltransferase activity | nucleus | --- | ---
U18760 | nuclear factor I/X (CCAAT-binding transcription factor) | NFIX | 8_10 | 0.019192893 | decreased | 1.303156105160886 | 35691_r_at | 164005 | ENSG00000008441 | 257970 | 4784 | NM_002501 |  | DNA replication /// DNA replication /// transcription /// regulation of transcription, DNA-dependent /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter | transcription factor activity /// transcription factor activity /// RNA polymerase II transcription factor activity, enhancer binding | nucleus /// nucleus | --- | ---
AL080071 | DKFZP564M082 protein | DKFZP564M082 | 9_10 | 0.02899563 | decreased | 1.347653085262087 | 35715_at | --- | ENSG00000110200 | 38044 | 25906 | NM_014042 |  | --- | --- | --- | --- | ---
L22342 | SP110 nuclear body protein | SP110 | 6_10 | 0.030615679 | decreased | 1.560725457764768 | 35718_at | 604457 | ENSG00000135899 | 145150 | 3431 | NM_004509 /// NM_004510 /// NM_080424 |  | regulation of transcription, DNA-dependent | transcription factor activity /// hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity | nucleus | --- | ---
U95740 | chromosome 16 open reading frame 45 | C16orf45 | 9_11 | 0.0245101 | decreased | 1.196000984087653 | 35742_at | --- | ENSG00000166780 | 460095 | 89927 | NM_033201 |  | --- | --- | --- | --- | ---
[NAME] | interleukin 13 receptor, alpha 1 | IL13RA1 | 2_10 | 0.000996941 | decreased | 2.462141436483822 | 35797_at | 300119 | ENSG00000131724 | 496646 | 3597 | NM_001560 |  | cell surface receptor linked signal transduction | receptor activity /// hematopoietin/interferon-class (D200-domain) cytokine receptor activity | [NAME] /// interleukin-13 receptor complex /// membrane /// integral to membrane | --- | ---
AL031681 | splicing factor, arginine/serine-rich 6 | SFRS6 | 3_11 | 0.01843725 | decreased | 1.911572417490592 | 35808_at | 601944 | ENSG00000124193 | 6891 | 6431 | [NAME] |  | nuclear mRNA splicing, via spliceosome /// mRNA splice site selection | nucleotide binding /// RNA binding | nucleus | mRNA_processing_Reactome | [NAME]
AL049470 | huntingtin interacting protein B | HYPB | 8_10 | 0.00545618 | decreased | 1.769285861671243 | 35815_at | --- | ENSG00000181555 | 517941 | 29072 | NM_012271 /// NM_014159 |  | metabolism | iron ion binding /// oxidoreductase activity | nucleus | --- | ---
X59766 | alpha-2-glycoprotein 1, zinc | AZGP1 | 10_10 | 0.020744088 | decreased | 1.603899688812254 | 35834_at | 194460 | ENSG00000160862 | 546239 | 563 | NM_001185 |  | cell adhesion /// negative regulation of cell proliferation /// lipid catabolism /// antigen presentation | ribonuclease activity /// fatty acid binding /// protein carrier activity /// MHC class I receptor activity | extracellular region /// MHC class I protein complex | --- | ---
AB020499 | [NAME] 86 | LY86 | 5_2 | 0.031994571 | increased | 2.028444051027995 | 35869_at | 605241 | ENSG00000112799 | 519866 | 9450 | NM_004271 |  | apoptosis /// inflammatory response /// humoral immune response /// signal transduction /// cell proliferation | signal transducer activity | plasma membrane | --- | ---
X99975 | --- | --- | 2_7 | 0.033177464 | decreased | 1.544779597161588 | 35873_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
D87845 | platelet-activating factor acetylhydrolase 2, 40kDa | PAFAH2 | 8_10 | 0.026591976 | decreased | 1.563070603948455 | 35874_at | 602344 | ENSG00000158006 | 477083 | 5051 | NM_000437 |  | lipid catabolism | 1-alkyl-2-acetylglycerophosphocholine esterase activity /// phospholipid binding /// hydrolase activity | soluble fraction /// cytoplasm /// 2-acetyl-1-alkylglycerophosphocholine esterase complex | Glycerophospholipid metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00564+3.1.1.47
W28826 | Retinaldehyde binding protein 1 | [NAME] | 10_10 | 0.008038471 | decreased | 1.230060377812008 | 35888_at | 136880 /// 180090 /// 268000 /// 607475 /// 607476 | ENSG00000140522 | 1933 | 6017 | NM_000326 |  | vitamin A metabolism /// transport /// sensory perception /// visual perception | transporter activity /// binding /// retinol binding | intracellular /// soluble fraction | --- | ---
AA877215 | heterogeneous nuclear ribonucleoprotein A3 | HNRPA3 | 3_10 | 0.006822752 | decreased | 2.125908230237723 | 35916_s_at | 605372 | ENSG00000170144 | 516539 | 220988 | NM_194247 |  | --- | nucleotide binding /// RNA binding | nucleus /// ribonucleoprotein complex | mRNA_processing_Reactome | [NAME]
X02133 | --- | --- | 3_10 | 0.01100072 | decreased | 1.907009823251885 | 35921_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
[NAME] | similar to PMS2 postmeiotic segregation increased 2 (S. cerevisiae) | LOC442573 | 2_7 | 0.007989327 | decreased | 3.266364742030416 | 35933_f_at | --- | --- | 278468 | 442573 | XM_499315 |  | --- | --- | --- | --- | ---
U90841 | synovial sarcoma, X breakpoint 1 /// synovial sarcoma, X breakpoint 4 /// synovial sarcoma, X breakpoint 6 /// synovial sarcoma, X breakpoint 9 | SSX1 /// SSX4 /// SSX6 /// SSX9 | 1_5 | 0.033612221 | increased | 2.882359058070759 | 35950_at | 312820 /// 300326 | ENSG00000126752 /// ENSG00000198946 /// ENSG00000171483 /// ENSG00000187754 | 434142 | 280657 /// 280660 /// 6756 /// 6759 | NM_005635 /// NM_005636 /// NM_173357 /// NM_174962 /// NM_175729 |  | transcription /// regulation of transcription, DNA-dependent | nucleic acid binding /// transcription corepressor activity | nucleus /// intracellular | --- | ---
X51758 | heat shock 70kDa protein 6 (HSP70B') | HSPA6 | 6_10 | 0.027858171 | decreased | 1.806199594297521 | 35965_at | 140555 | ENSG00000173110 | 3268 | 3310 | NM_002155 |  | protein folding /// response to unfolded protein | ATP binding | --- | --- | ---
AF041381 | E2F transcription factor 6 | E2F6 | 6_10 | 0.025762572 | decreased | 2.239718386851097 | 35984_at | 602944 | ENSG00000169016 | 135465 | 1876 | NM_001952 /// NM_198256 /// NM_198257 /// NM_198258 /// NM_198325 /// NM_212540 |  | regulation of cell cycle /// negative regulation of transcription from RNA polymerase II promoter /// transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// transcription corepressor activity | nucleus /// transcription factor complex | Cell_cycle_KEGG /// G1_to_S_cell_cycle_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G1_to_S_cell_cycle_Reactome/Hs_G1_to_S_cell_cycle_Reactome.htm
N30625 | apoptosis-inducing, [NAME]-like domain 1 | APITD1 | 6_11 | 0.013549143 | decreased | 1.429514956767676 | 36015_at | 609130 | ENSG00000175279 | --- | 378708 | --- |  | --- | DNA binding | --- | --- | ---
U57911 | chromosome 11 open reading frame 8 | C11orf8 | 4_8 | 0.025816336 | decreased | 1.656936951020149 | 36029_at | 600911 | ENSG00000066382 | 289795 | 744 | [NAME] |  | neurogenesis | hydrolase activity | --- | --- | ---
AL080214 | HOM-TES-103 tumor antigen-like | HOM-TES-103 | 4_11 | 0.020971537 | decreased | 1.628551766996996 | 36030_at | --- | ENSG00000010295 | 15243 | 25900 | NM_015438 /// NM_080730 /// NM_080731 |  | --- | --- | --- | --- | ---
AI337192 | SH3 domain binding glutamic acid-rich protein | SH3BGR | 4_11 | 0.025804843 | decreased | 1.717453491743391 | 36040_at | 602230 | ENSG00000185437 | 473847 | 6450 | NM_001001713 /// NM_007341 |  | protein complex assembly | SH3/SH2 adaptor activity | --- | --- | ---
AL096741 | activating signal cointegrator 1 complex subunit 2 | ASCC2 | 7_3 | 0.017381907 | increased | 1.186351086749615 | 36058_at | --- | ENSG00000100325 | 517438 | 84164 | NM_032204 |  | transcription /// regulation of transcription, DNA-dependent | --- | --- | --- | ---
AB011540 | low density lipoprotein receptor-related protein 4 | LRP4 | 10_10 | 0.020671545 | decreased | 1.330648169801097 | 36059_at | 604270 | ENSG00000134569 | 4930 | 4038 | NM_002334 |  | endocytosis | receptor activity /// calcium ion binding | membrane /// integral to membrane | --- | ---
AF002210 | copper chaperone for superoxide dismutase | CCS | 8_10 | 0.026760252 | decreased | 1.760669113506035 | 36068_at | 603864 | ENSG00000173992 | 502917 | 9973 | NM_005125 |  | protein folding /// superoxide metabolism /// intracellular copper ion transport /// metal ion transport | copper, zinc superoxide dismutase activity /// copper ion transporter activity /// copper ion binding /// metal ion binding /// unfolded protein binding | soluble fraction /// cytoplasm | --- | ---
AC002077 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 | GNAT1 | 7_1 | 0.024527454 | increased | 2.406490264869117 | 36085_at | 139330 | ENSG00000114349 | 517978 | 2779 | [NAME] /// NM_144499 |  | signal transduction /// G-protein coupled receptor protein signaling pathway /// sensory perception /// visual perception | GTPase activity /// signal transducer activity /// GTP binding | --- | --- | ---
AL080213 | phosphodiesterase 4D interacting protein (myomegalin) | PDE4DIP | 5_2 | 0.01036739 | increased | 2.458175543754362 | 36092_at | 608117 | ENSG00000178104 | 381235 | 9659 | NM_001002810 /// NM_001002811 /// NM_001002812 /// NM_014644 /// NM_022359 |  | protein biosynthesis /// cytoskeleton organization and biogenesis /// actin cytoskeleton organization and biogenesis | structural constituent of ribosome /// actin binding | intracellular /// ribosome /// actin cytoskeleton | --- | ---
X79204 | ataxin 1 | ATXN1 | 9_11 | 0.026580432 | decreased | 1.763207828914146 | 36142_at | 164400 /// 601556 | ENSG00000124788 | 434961 | 6310 | [NAME] |  | --- | RNA binding | nucleus /// cytoplasm | --- | ---
U48437 | amyloid beta (A4) precursor-like protein 1 | APLP1 | 7_3 | 0.027833084 | increased | 2.101140318462283 | 36148_at | 104775 | ENSG00000105290 | 74565 | 333 | NM_005166 |  | endocytosis /// apoptosis /// cell adhesion /// neurogenesis /// cell death | protein binding /// heparin binding | basement membrane /// coated pit /// integral to membrane | --- | ---
D87465 | sparc/osteonectin, cwcv and [NAME]-like domains proteoglycan (testican) 2 | SPOCK2 | 1_3 | 0.008158555 | increased | 1.769505730982614 | 36155_at | 607988 | ENSG00000107742 | 523009 | 9806 | NM_014767 |  | synaptogenesis /// extracellular matrix organization and biogenesis /// regulation of cell differentiation | calcium ion binding | extracellular matrix ([NAME]) | --- | ---
D83198 | ethylmalonic encephalopathy 1 | ETHE1 | 5_2 | 0.018655515 | increased | 3.115279896317185 | 36170_at | 602473 /// 608451 | ENSG00000105755 | 7486 | 23474 | NM_014297 |  | --- | hydrolase activity | --- | --- | ---
M12272 | alcohol dehydrogenase 1C (class I), gamma polypeptide | ADH1C | 2_10 | 0.006247877 | decreased | 1.708582425192138 | 36247_f_at | 103730 | ENSG00000196616 | 2523 | 126 | NM_000669 |  | alcohol metabolism | alcohol dehydrogenase activity, zinc-dependent /// zinc ion binding /// oxidoreductase activity | cytoplasm | Glycolysis / Gluconeogenesis /// Fatty acid metabolism /// Bile acid biosynthesis /// Tyrosine metabolism /// Glycerolipid metabolism | [NAME] /// [NAME] /// [NAME] /// [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00561+1.1.1.1
U41901 | limbic system-associated membrane protein | LSAMP | 10_10 | 0.01875243 | decreased | 1.006905791350256 | 36256_at | 603241 | ENSG00000185565 | 477234 | 4045 | NM_002338 |  | cell adhesion /// neurogenesis | protein binding | membrane fraction /// membrane | --- | ---
X77909 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | NFKBIL1 | 4_11 | 0.002971747 | decreased | 1.8159625000028 | 36267_at | 180300 /// 601022 | ENSG00000168593 | 2764 | 4795 | NM_005007 |  | cytoplasmic sequestering of transcription factor | --- | --- | --- | ---
U27331 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, [NAME] blood group included) /// fucosyltransferase 5 (alpha (1,3) fucosyltransferase) /// fucosyltransferase 6 (alpha (1,3) fucosyltransferase) | FUT3 /// FUT5 /// FUT6 | 8_10 | 0.016746534 | decreased | 2.326284961637212 | 36290_s_at | 111100 /// 136835 /// 136836 | ENSG00000171124 /// ENSG00000130383 /// ENSG00000156413 | 32956 | 2525 /// 2527 /// 2528 | NM_000149 /// NM_000150 /// NM_002034 |  | carbohydrate metabolism /// protein amino acid glycosylation /// carbohydrate metabolism /// protein amino acid glycosylation /// L-fucose catabolism | transferase activity, transferring glycosyl groups /// 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity /// alpha(1,3)-fucosyltransferase activity | membrane fraction /// Golgi apparatus /// membrane /// integral to membrane /// Golgi apparatus /// extracellular region | Blood group glycolipid biosynthesis-lactoseries | www.genome.ad.jp/dbget-bin/show_pathway?MAP00601+2.4.1.65
D76435 | Zic family member 1 (odd-paired homolog, Drosophila) | ZIC1 | 10_10 | 0.018870468 | decreased | 1.20148357886832 | 36308_at | 600470 | ENSG00000152977 | 41154 | 7545 | NM_003412 |  | pattern specification /// brain development /// behavior /// regulation of smoothened signaling pathway /// cell differentiation /// neuronal lineage restriction /// inner ear morphogenesis | transcription factor activity /// zinc ion binding | nucleus | --- | ---
U40370 | phosphodiesterase 1A, calmodulin-dependent | PDE1A | 8_10 | 0.005547625 | decreased | 1.914584221430514 | 36311_at | 171890 | ENSG00000115252 | 416061 | 5136 | NM_001003683 /// NM_005019 |  | signal transduction | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity /// calmodulin binding /// hydrolase activity | --- | G_Protein_Signaling /// Purine metabolism | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+3.1.4.17
AC005390 | KIAA0963 | KIAA0963 | 1_3 | 0.019415222 | increased | 1.895626610217354 | 36336_s_at | --- | ENSG00000064932 | 408708 | 22904 | NM_014963 |  | --- | --- | --- | --- | ---
AL049443 | TFIIA-alpha/beta-like factor | SBLF | 9_11 | 0.031295447 | decreased | 1.646186684409778 | 36396_at | 605357 | ENSG00000068781 | 44385 | 11037 | NM_006873 |  | --- | --- | --- | --- | ---
AI347155 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | PSMD9 | 9_11 | 0.011114488 | decreased | 1.505809960943051 | 36492_at | 603146 | ENSG00000110801 | 131151 | 5715 | NM_002813 |  | ubiquitin-dependent protein catabolism | protein binding | cytosol /// proteasome regulatory particle (sensu [NAME]) | Proteasome_Degradation | [NAME]
S87759 | protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform | PPM1A | 6_11 | 0.008086595 | decreased | 2.089677405636264 | 36501_at | 606108 | ENSG00000100614 | 130036 | 5494 | NM_021003 /// NM_177951 /// NM_177952 |  | protein amino acid dephosphorylation /// positive regulation of I-kappaB kinase/NF-kappaB cascade | magnesium ion binding /// signal transducer activity /// protein phosphatase type 2C activity /// hydrolase activity /// manganese ion binding | protein serine/threonine phosphatase complex | --- | ---
AL080143 | zinc finger protein 473 | ZNF473 | 2_10 | 0.012825101 | decreased | 2.154246143831859 | 36516_at | --- | ENSG00000142528 | 440553 | 25888 | NM_001006656 /// NM_015428 |  | regulation of transcription, DNA-dependent | DNA binding /// zinc ion binding | nucleus | --- | ---
X87176 | hydroxysteroid (17-beta) dehydrogenase 4 | HSD17B4 | 10_10 | 0.006539056 | decreased | 1.746013543054552 | 36626_at | 261515 /// 601860 | ENSG00000133835 | 406861 | 3295 | NM_000414 |  | lipid metabolism /// fatty acid metabolism /// metabolism | 3-hydroxyacyl-CoA dehydrogenase activity /// estradiol 17-beta-dehydrogenase activity /// sterol carrier activity /// sterol transporter activity /// oxidoreductase activity /// lyase activity /// isomerase activity | peroxisome | Steroid_Biosynthesis | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Steroid_Biosynthesis/Hs_Steroid_Biosynthesis.htm
D21261 | transgelin 2 | TAGLN2 | 5_6 | 0.031858145 | increased | 2.283803034529071 | 36678_at | 604634 | ENSG00000117063 | 517168 | 8407 | NM_003564 |  | muscle development | --- | --- | --- | ---
N50520 | cytochrome c oxidase subunit VIIb | COX7B | 9_11 | 0.019738457 | decreased | 1.660247904106326 | 36687_at | 603792 | ENSG00000131174 | 522699 | 1349 | NM_001866 |  | electron transport | cytochrome-c oxidase activity /// oxidoreductase activity | mitochondrion /// mitochondrial electron transport chain /// integral to membrane /// inner membrane | Electron_Transport_Chain /// Oxidative phosphorylation | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00190+1.9.3.1
U86358 | chemokine (C-C motif) ligand 25 | CCL25 | 5_1 | 0.030995786 | increased | 2.387579148866703 | 36703_at | 602565 | ENSG00000131142 | 310511 | 6370 | NM_005624 /// NM_148888 |  | chemotaxis /// inflammatory response /// G-protein coupled receptor protein signaling pathway /// sensory perception | hormone activity /// chemokine activity | extracellular region /// soluble fraction | --- | ---
L27586 | nuclear receptor subfamily 2, group C, member 2 | NR2C2 | 1_5 | 0.01877857 | increased | 3.735284612631134 | 36714_at | 601426 | ENSG00000177463 | 549074 | 7182 | NM_003298 |  | transcription /// regulation of transcription, DNA-dependent /// neurogenesis | transcription factor activity /// steroid hormone receptor activity /// transcription coactivator activity | nucleus | Nuclear_Receptors | [NAME]
D25235 | adrenergic, alpha-1A-, receptor | ADRA1A | 3_10 | 0.025597217 | decreased | 2.216053581749237 | 36715_at | 104221 | ENSG00000120907 | 52931 | 148 | NM_000680 /// NM_033302 /// NM_033303 /// NM_033304 |  | apoptosis /// smooth muscle contraction /// signal transduction /// G-protein coupled receptor protein signaling pathway /// protein kinase cascade /// cell-cell signaling /// negative regulation of cell proliferation | rhodopsin-like receptor activity /// receptor activity /// adrenoceptor activity /// [NAME] receptor activity /// [NAME] receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Monoamine_GPCRs /// Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Monoamine_GPCRs/Hs_Monoamine_GPCRs.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
U95626 | chemokine (C-C motif) receptor 5 | CCR5 | 6_10 | 0.022738979 | decreased | 1.990417342318828 | 36724_s_at | 601373 | ENSG00000188239 /// ENSG00000160791 | 546245 | 1234 | NM_000579 |  | G-protein coupled receptor protein signaling pathway | rhodopsin-like receptor activity /// receptor activity /// C-C chemokine receptor activity | integral to membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs /// GPCRDB_Other | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Other/Hs_GPCRDB_Other.htm
M64936 | --- | --- | 2_7 | 0.013791329 | decreased | 1.925338480122522 | 36727_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
M76446 | adrenergic, alpha-1D-, receptor | ADRA1D | 7_3 | 0.034032232 | increased | 1.717894585175396 | 36729_g_at | 104219 | ENSG00000171873 | 557 | 146 | NM_000678 |  | DNA metabolism /// signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein signaling, coupled to cAMP nucleotide second messenger /// cell-cell signaling /// development /// cell proliferation /// positive regulation of cell proliferation | rhodopsin-like receptor activity /// receptor activity /// adrenoceptor activity /// [NAME] receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Monoamine_GPCRs /// Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Monoamine_GPCRs/Hs_Monoamine_GPCRs.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
AF025534 | [NAME] receptor, subfamily B (with TM and ITIM domains), member 5 | LILRB5 | 7_3 | 0.023624635 | increased | 2.030590864053684 | 36789_f_at | 604814 | ENSG00000105609 | 306230 | 10990 | NM_006840 |  | immune response /// cell surface receptor linked signal transduction | [NAME] receptor activity | integral to membrane | --- | ---
L37882 | frizzled homolog 2 (Drosophila) | FZD2 | 1_4 | 0.035414939 | increased | 2.113503543128817 | 36799_at | 600667 | ENSG00000180340 | 142912 | 2535 | NM_001466 |  | establishment of tissue polarity /// G-protein coupled receptor protein signaling pathway /// development /// Wnt receptor signaling pathway | [NAME] coupled 7TM receptor activity /// G-protein coupled receptor activity | integral to plasma membrane /// membrane | Wnt_signaling | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm
AL050367 | chromosome 10 open reading frame 38 | C10orf38 | 2_10 | 0.028657267 | decreased | 1.183366708849505 | 36821_at | --- | --- | 66762 | 221061 | XM_167709 |  | --- | --- | --- | --- | ---
X64037 | general transcription factor IIF, polypeptide 1, 74kDa | GTF2F1 | 5_3 | 0.003247601 | increased | 2.017492545995184 | 36826_at | 189968 | ENSG00000125651 | 68257 | 2962 | NM_002096 |  | transcription /// regulation of transcription, DNA-dependent /// transcription initiation from RNA polymerase II promoter /// positive regulation of transcription | magnesium ion binding /// DNA binding /// transcription coactivator activity /// protein serine/threonine kinase activity /// protein binding /// ATP binding /// general [NAME] polymerase II transcription factor activity /// transcriptional activator activity /// transferase activity | nucleus /// transcription factor TFIIF complex | --- | ---
X71129 | electron-transfer-flavoprotein, beta polypeptide | ETFB | 4_11 | 0.003111752 | decreased | 2.340141118534035 | 36881_at | 130410 /// 231680 | ENSG00000105379 | 74047 | 2109 | NM_001014763 /// NM_001985 |  | electron transport /// transport | electron carrier activity | mitochondrial matrix | --- | ---
M97287 | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | SATB1 | 4_11 | 0.023937051 | decreased | 1.621080205202489 | 36899_at | 602075 | ENSG00000182568 | 517717 | 6304 | NM_002971 |  | establishment and/or maintenance of chromatin architecture /// regulation of transcription, DNA-dependent | double-stranded DNA binding /// transcription factor activity | nucleus | --- | ---
M23379 | RAS p21 protein activator (GTPase activating protein) 1 | RASA1 | 5_2 | 0.023988893 | increased | 1.060430652149757 | 36935_at | 139150 /// 608354 /// 608355 | ENSG00000145715 | 292524 | 5921 | NM_002890 /// NM_022650 |  | intracellular signaling cascade | [NAME] activator activity | --- | --- | ---
X00442 | chemokine (C-X-C motif) ligand 2 /// haptoglobin /// haptoglobin-related protein | CXCL2 /// HP /// HPR | 6_10 | 0.026171691 | decreased | 2.543786679975453 | 36983_f_at | 139110 /// 140100 /// 140210 | ENSG00000081041 /// ENSG00000197711 | 512155 | 2920 /// 3240 /// 3250 | NM_002089 /// NM_005143 /// NM_020995 |  | chemotaxis /// inflammatory response /// G-protein coupled receptor protein signaling pathway /// sensory perception /// proteolysis and peptidolysis /// iron ion homeostasis /// defense response | chemokine activity /// chymotrypsin activity /// trypsin activity /// hemoglobin binding /// hemoglobin binding | extracellular space /// soluble fraction /// extracellular region /// extracellular region | --- | ---
AL031295 | lysophospholipase II | LYPLA2 | 5_2 | 0.020027638 | increased | 1.564294688021348 | 36986_at | --- | ENSG00000011009 | 533479 | 11313 | NM_007260 |  | lipid metabolism /// fatty acid metabolism | hydrolase activity | --- | Glycerophospholipid metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00564+3.1.1.5
J04809 | adenylate kinase 1 | AK1 | 4_11 | 0.010816909 | decreased | 2.51885661286453 | 36997_at | 103000 | ENSG00000106992 | 175473 | 203 | NM_000476 |  | nucleobase, nucleoside, nucleotide and nucleic acid metabolism /// ATP metabolism | adenylate kinase activity /// ATP binding /// kinase activity /// transferase activity | [NAME] | Purine metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+2.7.4.3
D13900 | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | ECHS1 | 4_11 | 0.016300231 | decreased | 1.612278572834365 | 37016_at | 602292 | ENSG00000127884 | 76394 | 1892 | NM_004092 |  | generation of precursor metabolites and energy /// lipid metabolism /// fatty acid metabolism /// fatty acid beta-oxidation /// metabolism | enoyl-CoA hydratase activity /// lyase activity | mitochondrion | Fatty acid biosynthesis (path 2) /// Fatty acid metabolism /// [NAME], leucine and isoleucine degradation /// Lysine degradation /// Tryptophan metabolism /// beta-Alanine metabolism /// Benzoate degradation via CoA ligation /// Propanoate metabolism /// Butanoate metabolism /// [NAME] and pinene degradation | www.genome.ad.jp/dbget-bin/show_pathway?MAP00062+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00071+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00280+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00310+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00410+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00632+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00640+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00650+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00903+4.2.1.17
M22430 | phospholipase A2, group IIA (platelets, synovial fluid) | PLA2G2A | 7_3 | 0.005562884 | increased | 1.830114611602615 | 37017_at | 172411 | ENSG00000188257 | 466804 | 5320 | NM_000300 |  | lipid catabolism | calcium ion binding /// hydrolase activity /// calcium-dependent phospholipase A2 activity | extracellular region /// membrane | Eicosanoid_Synthesis /// Glycerophospholipid metabolism /// Prostaglandin and leukotriene metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Eicosanoid_Synthesis/Hs_Eicosanoid_Synthesis.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00564+3.1.1.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00590+3.1.1.4
X83218 | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | ATP5O | 9_11 | 0.006451505 | decreased | 1.750532693343419 | 37029_at | 600828 | ENSG00000159186 | 409140 | 539 | NM_001697 |  | ion transport /// ATP synthesis coupled proton transport /// proton transport | transporter activity /// hydrolase activity /// hydrogen-transporting ATP synthase activity, rotational mechanism /// hydrogen-transporting ATPase activity, rotational mechanism | membrane fraction /// mitochondrion /// proton-transporting ATP synthase complex (sensu [NAME]) /// proton-transporting two-sector ATPase complex | Electron_Transport_Chain /// Oxidative phosphorylation /// ATP synthesis /// Photosynthesis /// [NAME] assembly /// Type III secretion system | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00190+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00193+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00195+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP02040+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03070+3.6.3.14
Y15195 | A kinase (PRKA) anchor protein 4 | AKAP4 | 8_10 | 0.0273519 | decreased | 2.112499969288337 | 37087_at | 300185 | ENSG00000147081 | 97633 | 8852 | NM_003886 /// NM_139289 |  | cell motility /// signal transduction /// signal transduction /// fertilization (sensu Metazoa) /// sperm motility | kinase activity /// protein kinase A binding /// protein kinase A binding | [NAME] /// cAMP-dependent protein kinase complex | G_Protein_Signaling | [NAME]
U93305 | synaptophysin | SYP | 1_3 | 0.026173321 | increased | 1.883656171557372 | 37182_at | 313475 | ENSG00000102003 | 75667 | 6855 | NM_003179 |  | transport /// synaptic vesicle maturation /// synaptic vesicle membrane organization and biogenesis | transporter activity /// calcium ion binding /// protein binding /// cholesterol binding | synaptic vesicle /// membrane /// synaptosome /// integral to synaptic vesicle membrane /// synapse | --- | ---
D87459 | WAS protein family, member 1 | WASF1 | 7_3 | 0.029315367 | increased | 2.153514567411951 | 37190_at | 605035 | ENSG00000112290 | 75850 | 8936 | NM_003931 |  | protein complex assembly /// cell motility /// actin filament polymerization | [NAME] binding | [NAME] | --- | ---
U79260 | fatso | FTO | 9_11 | 0.031764132 | decreased | 2.052064664800394 | 37242_at | --- | ENSG00000140718 | 528833 | 79068 | XM_051200 |  | --- | --- | --- | --- | ---
X63469 | general transcription factor IIE, polypeptide 2, beta 34kDa | GTF2E2 | 9_11 | 0.007453409 | decreased | 1.769971479607802 | 37295_at | 189964 | ENSG00000197265 | 77100 | 2961 | NM_002095 |  | transcription /// regulation of transcription, DNA-dependent /// transcription initiation from RNA polymerase II promoter | protein binding /// general [NAME] polymerase II transcription factor activity | nucleus /// transcription factor TFIIE complex | RNA_transcription_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_RNA_transcription_Reactome/Hs_RNA_transcription_Reactome.htm
X54871 | RAB5B, member RAS oncogene family | RAB5B | 9_11 | 0.008942988 | decreased | 1.932117257338184 | 37362_at | 179514 | ENSG00000111540 | 77690 | 5869 | NM_002868 |  | intracellular protein transport /// small GTPase mediated signal transduction | GTP binding /// GTP-dependent protein binding | endosome | --- | ---
AB007889 | metastasis suppressor 1 | MTSS1 | 10_10 | 0.033030309 | decreased | 0.9611995166643893 | 37363_at | 608486 | ENSG00000170873 | 336994 | 9788 | NM_014751 |  | cell motility /// cell cycle /// cell adhesion /// transmembrane receptor [NAME] signaling pathway /// neurogenesis /// muscle development /// microspike biogenesis /// actin cytoskeleton organization and biogenesis /// negative regulation of cell cycle | [NAME] binding /// receptor binding | ruffle /// cytoplasm /// actin cytoskeleton /// endocytic vesicle | --- | ---
X12451 | cathepsin L | CTSL | 5_2 | 0.031298409 | increased | 2.487201222936128 | 37391_at | 116880 | ENSG00000135047 | 418123 | 1514 | NM_001912 /// NM_145918 |  | proteolysis and peptidolysis | cathepsin L activity | extracellular region /// lysosome | --- | ---
D17793 | aldo-keto reductase family 1, member [NAME] (3-alpha hydroxysteroid dehydrogenase, type II) | AKR1C3 | 9_11 | 0.009037801 | decreased | 1.562861687172108 | 37399_at | 603966 | ENSG00000196139 | 78183 | 8644 | NM_003739 |  | lipid metabolism /// prostaglandin metabolism /// cell proliferation | aldo-keto reductase activity /// electron transporter activity /// prostaglandin-F synthase activity /// trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity | --- | --- | ---
U29091 | selenium binding protein 1 | SELENBP1 | 9_11 | 0.012057707 | decreased | 1.767095935597378 | 37405_at | 604188 | ENSG00000143416 | 334841 | 8991 | [NAME] |  | --- | selenium binding /// selenium binding | --- | --- | ---
AJ224358 | surfeit 5 | [NAME] | 4_11 | 0.005729884 | decreased | 1.647384406910519 | 37410_at | 185641 | ENSG00000148297 | 78354 | 6837 | /// NM_006752 /// NM_133640 /// NM_181491 |  | --- | --- | soluble fraction /// cytoplasm /// cytoplasm | --- | ---
[NAME] | [NAME], member RAS oncogene family-like 1 | RAB7L1 | 6_10 | 0.027903602 | decreased | 0.9974915038665605 | 37466_at | 603949 | ENSG00000117280 | 115325 | 8934 | NM_003929 |  | intracellular protein transport /// small GTPase mediated signal transduction | GTPase activity /// GTP binding | --- | --- | ---
[NAME] | nuclear receptor subfamily 0, group B, member 2 | NR0B2 | 7_3 | 0.008685997 | increased | 1.182191572044763 | 37505_at | 601665 /// 604630 | ENSG00000131910 | 427055 | 8431 | NM_021969 |  | negative regulation of transcription from RNA polymerase II promoter /// transcription /// regulation of transcription, DNA-dependent /// cholesterol metabolism | transcription factor activity /// steroid hormone receptor activity /// transcription corepressor activity | nucleus | --- | ---
D86965 | TBC1 domain family, member 5 | TBC1D5 | 6_10 | 0.015321667 | decreased | 2.489131787287526 | 37531_at | --- | ENSG00000131374 | 475629 | 9779 | NM_014744 |  | --- | GTPase activator activity | --- | --- | ---
M91432 | acyl-Coenzyme A dehydrogenase, [NAME] to C-12 straight chain | ACADM | 9_11 | 0.029984933 | decreased | 1.246698019414164 | 37532_at | 201450 /// 607008 | ENSG00000117054 | 445040 | 34 | NM_000016 |  | electron transport /// lipid metabolism /// fatty acid metabolism /// fatty acid beta-oxidation | acyl-CoA dehydrogenase activity /// acyl-CoA dehydrogenase activity /// oxidoreductase activity | mitochondrion /// mitochondrial matrix | Fatty_Acid_Degradation /// Mitochondrial_fatty_acid_betaoxidation /// Fatty acid metabolism /// [NAME], leucine and isoleucine degradation /// beta-Alanine metabolism /// Propanoate metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Fatty_Acid_Degradation/Hs_Fatty_Acid_Degradation.htm /// www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Mitochondrial_fatty_acid_betaoxidation/Hs_Mitochondrial_fatty_acid_betaoxidation.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00071+1.3.99.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00280+1.3.99.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00410+1.3.99.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00640+1.3.99.3
W84438 | hypothetical protein MGC61716 | MGC61716 | 6_10 | 0.014597665 | decreased | 1.780396682447297 | 37559_at | --- | ENSG00000122085 | 159556 | 130916 | NM_182501 |  | --- | --- | --- | --- | ---
AF017060 | --- | --- | 4_11 | 0.003929047 | decreased | 2.18540570285369 | 37599_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
X63578 | parvalbumin | PVALB | 1_3 | 0.007287705 | increased | 1.659937376570181 | 37614_g_at | 168890 | ENSG00000100362 | 295449 | 5816 | NM_002854 |  | muscle development | calcium ion binding | --- | --- | ---
AF104421 | uroporphyrinogen decarboxylase | UROD | 9_11 | 0.021702259 | decreased | 1.388338378844976 | 37667_at | 176100 | ENSG00000126088 | 78601 | 7389 | NM_000374 |  | heme biosynthesis | uroporphyrinogen decarboxylase activity /// lyase activity | --- | Heme_Biosynthesis /// [NAME] and chlorophyll metabolism | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00860+4.1.1.37
AF056490 | phosphodiesterase 8A | PDE8A | 3_10 | 0.021520459 | decreased | 1.967679933257921 | 37676_at | 602972 | ENSG00000073417 | 9333 | 5151 | NM_002605 /// NM_173454 /// NM_173455 /// NM_173456 /// NM_173457 |  | signal transduction /// cyclic nucleotide metabolism | magnesium ion binding /// 3',5'-cyclic-nucleotide phosphodiesterase activity /// signal transducer activity /// hydrolase activity /// manganese ion binding | --- | G_Protein_Signaling /// Purine metabolism | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+3.1.4.17
L13463 | regulator of G-protein signalling 2, 24kDa | RGS2 | 3_10 | 0.034322682 | decreased | 2.78073256657297 | 37701_at | 600861 | ENSG00000116741 | 78944 | 5997 | NM_002923 |  | cell cycle /// signal transduction /// regulation of G-protein coupled receptor protein signaling pathway | signal transducer activity /// GTPase activator activity /// calmodulin binding | --- | Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
AB014517 | cullin 3 | CUL3 | 3_10 | 0.033036865 | decreased | 1.432865308571636 | 37702_at | 603136 | ENSG00000036257 | 372286 | 8452 | NM_003590 |  | G1/S transition of mitotic cell cycle /// ubiquitin cycle /// cell cycle /// cell cycle arrest /// positive regulation of cell proliferation /// induction of apoptosis by intracellular signals | --- | nucleus | --- | ---
AF045184 | SKI interacting protein | SKIIP | 4_11 | 0.017188123 | decreased | 2.917585827175727 | 37715_at | 603055 | [NAME] | 445498 | 22938 | NM_012245 |  | nuclear mRNA splicing, via spliceosome /// regulation of transcription from RNA polymerase II promoter | transcription coactivator activity | spliceosome complex | --- | ---
AB020711 | CDC2-related protein kinase 7 | CRK7 | 10_10 | 0.00676113 | decreased | 2.116069646927537 | 37772_at | --- | ENSG00000167258 | 416108 | 51755 | NM_016507 |  | autophosphorylation | RNA polymerase II transcription factor activity /// protein serine/threonine kinase activity /// ATP binding /// transferase activity | nucleus | --- | ---
Y08134 | sphingomyelin phosphodiesterase, acid-like 3B | SMPDL3B | 5_2 | 0.029159176 | increased | 1.896148797619914 | 37779_at | --- | ENSG00000130768 | 123659 | 27293 | NM_001009568 /// NM_014474 |  | carbohydrate metabolism | hydrolase activity /// hydrolase activity, acting on glycosyl bonds | --- | --- | ---
AB006631 | cut-like 2 (Drosophila) | CUTL2 | 8_10 | 0.032569417 | decreased | 2.5274200928922 | 37812_at | --- | ENSG00000111249 | 124953 | 23316 | NM_015267 |  | regulation of transcription, DNA-dependent | transcription factor activity | nucleus | --- | ---
AF007130 | Mdm4, transformed 3T3 cell double minute 1, p53 binding protein (mouse) | [NAME] | 9_11 | 0.027435129 | decreased | 1.967589275517684 | 37819_at | --- | ENSG00000111554 | 171265 | 56890 | NM_017440 /// NM_020128 |  | --- | --- | nucleus | --- | ---
AB028997 | ankyrin repeat domain 26 | ANKRD26 | 1_5 | 0.007690488 | increased | 2.384544792656256 | 37824_at | --- | ENSG00000107890 | 361041 | 22852 | NM_014915 |  | --- | --- | --- | --- | ---
AF055019 | Homeodomain interacting protein kinase 2 | HIPK2 | 3_10 | 0.023281779 | decreased | 2.097698153653211 | 37851_at | 606868 | ENSG00000064393 | 397465 | 28996 | NM_022740 |  | regulation of cell cycle /// transcription /// regulation of transcription, DNA-dependent /// protein amino acid phosphorylation /// apoptosis /// induction of apoptosis by intracellular signals /// virus-host interaction /// positive regulation of transforming growth factor beta receptor signaling pathway /// positive regulation of JNK cascade | transcription corepressor activity /// protein serine/threonine kinase activity /// protein binding /// ATP binding /// transferase activity /// virion binding | nucleus /// cytoplasm /// nuclear body | --- | ---
AJ001564 | immunoglobulin heavy locus /// immunoglobulin heavy constant gamma 1 (G1m marker) /// immunoglobulin heavy constant gamma 2 (G2m marker) /// immunoglobulin heavy constant gamma 3 (G3m marker) /// immunoglobulin heavy constant gamma 4 (G4m marker) /// immunoglobulin heavy constant mu | IGH@ /// IGHG1 /// IGHG2 /// IGHG3 /// IGHG4 /// IGHM | 3_10 | 0.020607076 | decreased | 2.131388935361372 | 37864_s_at | 147100 /// 147110 /// 147120 /// 147130 /// 147020 /// 601495 | --- | 534324 | 3492 /// 3500 /// 3501 /// 3502 /// 3503 /// 3507 | --- |  | immune response /// immune response | antigen binding /// antigen binding /// antigen binding /// antigen binding /// antigen binding /// antigen binding /// receptor activity | membrane fraction /// integral to membrane /// membrane | --- | ---
AF100907 | growth differentiation factor 11 | GDF11 | 6_8 | 0.027776971 | decreased | 2.694120441829823 | 37881_at | 603936 | ENSG00000135414 | 550500 | 10220 | NM_005811 |  | skeletal development /// neurogenesis /// mesoderm development /// growth | cytokine activity /// growth factor activity | --- | --- | ---
AJ245434 | apolipoprotein M | APOM | 7_3 | 0.010661548 | increased | 1.647335195139492 | 37925_r_at | 606907 | ENSG00000111964 | 534468 | 55937 | NM_019101 |  | generation of precursor metabolites and energy /// membrane lipid metabolism /// lipid transport | lipid transporter activity | integral to plasma membrane | --- | ---
AA806768 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C | APOBEC3C | 4_11 | 0.015548439 | decreased | 1.990867365317936 | 37940_f_at | 607750 | ENSG00000198904 | 441124 | 27350 | NM_014508 |  | --- | RNA binding /// zinc ion binding /// hydrolase activity /// hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | --- | --- | ---
AL031177 | APG4 autophagy 4 homolog A (S. cerevisiae) | APG4A | 3_10 | 0.013915368 | decreased | 1.626287286170141 | 37957_at | --- | ENSG00000101844 | 8763 | 115201 | NM_052936 /// NM_178270 /// NM_178271 |  | autophagic vacuole formation /// proteolysis and peptidolysis /// protein-membrane targeting /// protein-vacuolar targeting /// autophagy /// protein transport | protein binding /// microtubule binding /// cysteine-type peptidase activity | cytosol /// microtubule associated complex | --- | ---
U03272 | fibrillin 2 (congenital contractural arachnodactyly) | FBN2 | 5_2 | 0.030825186 | increased | 1.871252454559445 | 38012_at | 121050 | ENSG00000138829 | 519294 | 2201 | NM_001999 |  | morphogenesis | extracellular matrix structural constituent /// calcium ion binding | extracellular matrix ([NAME]) | --- | ---
AB014552 | KIAA0652 gene product | KIAA0652 | 3_11 | 0.000546909 | decreased | 1.43145922688819 | 38020_at | --- | ENSG00000175224 | 410092 | 9776 | NM_014741 |  | --- | --- | --- | --- | ---
AB002330 | U2-associated SR140 protein | SR140 | 8_10 | 0.009890897 | decreased | 1.257705791042581 | 38030_at | --- | ENSG00000163714 | 529577 | 23350 | XM_031553 |  | RNA processing | nucleotide binding /// RNA binding | --- | --- | ---
AJ005579 | IK cytokine, down-regulator of HLA II | IK | 9_11 | 0.034108033 | decreased | 1.225876452226081 | 38046_at | 600549 | ENSG00000113141 | 421245 | 3550 | NM_006083 |  | immune response /// cell-cell signaling | cytokine activity | extracellular space /// soluble fraction | --- | ---
D38555 | SEC24 related gene family, member C (S. cerevisiae) | SEC24C | 8_10 | 0.000694196 | decreased | 1.821626896953807 | 38117_at | 607185 | ENSG00000176986 | 81964 | 9632 | NM_004922 /// NM_198597 |  | intracellular protein transport /// ER to Golgi transport | [NAME] binding /// protein binding | endoplasmic reticulum /// Golgi apparatus /// COPII vesicle coat | --- | ---
M14083 | serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | SERPINE1 | 5_2 | 0.00982709 | increased | 1.485876644406429 | 38125_at | 173360 | ENSG00000106366 | 414795 | 5054 | NM_000602 |  | blood coagulation | serine-type endopeptidase inhibitor activity /// plasminogen activator activity | extracellular region | TGF_Beta_Signaling_Pathway /// Blood_Clotting_Cascade | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_TGF_Beta_Signaling_Pathway/Hs_TGF_Beta_Signaling_Pathway.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Blood_Clotting_Cascade/Hs_Blood_Clotting_Cascade.htm
D29642 | Rho GTPase activating protein 25 | ARHGAP25 | 10_10 | 0.00918604 | decreased | 1.60787148493866 | 38149_at | --- | ENSG00000163219 | 531807 | 9938 | NM_001007231 /// NM_014882 |  | --- | GTPase activator activity | --- | --- | ---
AF059252 | dom-3 homolog Z (C. elegans) | DOM3Z | 4_10 | 0.00255785 | decreased | 1.519983968503292 | 38157_at | 605996 | ENSG00000168493 | 153299 | 1797 | /// NM_005510 |  | --- | --- | --- | --- | ---
AF011333 | [NAME] 75 | [NAME] | 1_5 | 0.006091345 | increased | 2.028172616508153 | 38160_at | 604524 | ENSG00000054219 | 153563 | 4065 | NM_002349 |  | endocytosis /// inflammatory response | receptor activity /// sugar binding | integral to plasma membrane | --- | ---
AF010403 | myeloid/lymphoid or mixed-lineage leukemia 2 | MLL2 | 1_1 | 0.006027909 | increased | 1.92747131352192 | 38165_s_at | 602113 | ENSG00000167548 | 387381 | 8085 | NM_003482 |  | transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// protein ubiquitination | transcription factor activity /// ubiquitin-protein ligase activity /// zinc ion binding | ubiquitin ligase complex /// nucleus | --- | ---
AJ001015 | receptor (calcitonin) activity modifying protein 2 | RAMP2 | 8_11 | 0.029551857 | decreased | 1.279704638461422 | 38177_at | 605154 | ENSG00000131477 | 514193 | 10266 | NM_005854 |  | intracellular protein transport /// receptor mediated endocytosis /// cell surface receptor linked signal transduction /// regulation of G-protein coupled receptor protein signaling pathway | receptor activity /// protein transporter activity | lysosome /// integral to plasma membrane /// coated pit | Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
U31248 | zinc finger protein 174 | ZNF174 | 8_10 | 0.006435456 | decreased | 2.038677847725098 | 38179_at | 603900 | ENSG00000103343 | 155204 | 7727 | [NAME] |  | negative regulation of transcription from RNA polymerase II promoter /// transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// protein binding /// zinc ion binding | nucleus | --- | ---
X57766 | matrix metalloproteinase 11 (stromelysin 3) | MMP11 | 5_2 | 0.020769643 | increased | 1.078860504151181 | 38181_at | 185261 | ENSG00000099953 | 143751 | 4320 | NM_005940 |  | proteolysis and peptidolysis /// morphogenesis /// collagen catabolism | metalloendopeptidase activity /// stromelysin 3 activity /// calcium ion binding /// zinc ion binding | extracellular matrix (sensu Metazoa) /// extracellular matrix ([NAME]) | Matrix_Metalloproteinases | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Matrix_Metalloproteinases/Hs_Matrix_Metalloproteinases.htm
M89470 | paired box gene 2 | [NAME] | 10_10 | 0.022874853 | decreased | 2.008852936878602 | 38184_at | 120330 /// 167409 | ENSG00000075891 | 155644 | 5076 | NM_000278 /// NM_003987 /// NM_003988 /// NM_003989 /// NM_003990 |  | GTP biosynthesis /// UTP biosynthesis /// CTP biosynthesis /// transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// development /// axonogenesis /// visual perception /// cell differentiation | DNA binding /// DNA binding /// nucleoside-diphosphate kinase activity /// ATP binding | nucleus | --- | ---
W27152 | hypothetical protein FLJ10569 | [NAME] | 9_11 | 0.02045299 | decreased | 1.378511482687629 | 38226_at | --- | ENSG00000104613 | 512627 | 55174 | NM_018142 |  | --- | --- | --- | --- | ---
AL050306 | LAS1-like (S. cerevisiae) | LAS1L | 3_11 | 0.003778097 | decreased | 1.628667183684924 | 38260_at | --- | ENSG00000001497 | 522675 | 81887 | NM_031206 |  | --- | --- | --- | --- | ---
AF070607 | histone deacetylase 4 | [NAME] | 2_11 | 0.035129613 | decreased | 1.711263082522832 | 38271_at | 605314 | ENSG00000068024 | 20516 | 9759 | NM_006037 |  | transcription /// regulation of transcription, DNA-dependent /// inflammatory response /// cell cycle /// development /// neurogenesis /// chromatin modification /// B-cell differentiation /// negative regulation of myogenesis | histone deacetylase activity /// transcription factor binding /// transcriptional repressor activity /// hydrolase activity | histone deacetylase complex /// nucleus /// cytoplasm | [NAME] | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm
X04706 | homeo box D4 | HOXD4 | 9_11 | 0.030134696 | decreased | 1.61965870953034 | 38294_at | 142981 | ENSG00000170166 | 386365 | 3233 | NM_014621 |  | regulation of transcription, DNA-dependent /// development | transcription factor activity | nucleus | --- | ---
AB015228 | aldehyde dehydrogenase 1 family, member A2 | ALDH1A2 | 6_10 | 0.004822162 | decreased | 1.621017012497963 | 38315_at | 603687 | ENSG00000128918 | 435689 | 8854 | NM_003888 /// NM_170696 /// NM_170697 |  | vitamin A metabolism /// metabolism | retinal dehydrogenase activity /// aldehyde dehydrogenase activity /// electron transporter activity /// oxidoreductase activity | --- | Glycolysis / Gluconeogenesis /// Ascorbate and aldarate metabolism /// Fatty acid metabolism /// Bile acid biosynthesis /// [NAME], leucine and isoleucine degradation /// Lysine degradation /// Arginine and proline metabolism /// Histidine metabolism /// Tryptophan metabolism /// beta-Alanine metabolism /// Glycerolipid metabolism /// Pyruvate metabolism /// 1,2-Dichloroethane degradation /// Propanoate metabolism /// Butanoate metabolism /// [NAME] and pinene degradation | www.genome.ad.jp/dbget-bin/show_pathway?MAP00010+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00053+1.2.1.3 /// [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00120+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00280+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00310+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00330+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00340+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00410+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00561+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00620+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00631+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00640+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00650+1.2.1.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00903+1.2.1.3
AA919102 | CD3D antigen, delta polypeptide (TiT3 complex) | CD3D | 3_10 | 0.026955207 | decreased | 1.23992032697624 | 38319_at | 186790 /// 600802 | ENSG00000167286 | 504048 | 915 | NM_000732 |  | protein complex assembly /// cell surface receptor linked signal transduction /// T-cell activation /// positive thymic T-cell selection | [NAME] receptor activity /// protein binding /// protein heterodimerization activity | cytoplasm /// membrane /// integral to membrane /// T-cell receptor complex | --- | ---
Z34975 | component of oligomeric golgi complex 2 | COG2 | 8_10 | 0.007923235 | decreased | 1.555597815947042 | 38390_at | 606974 | ENSG00000135775 | 211800 | 22796 | NM_007357 |  | protein amino acid glycosylation /// intracellular protein transport /// intra-Golgi transport /// Golgi organization and biogenesis /// oligosaccharide biosynthesis | protein transporter activity | Golgi membrane /// membrane /// Golgi transport complex | --- | ---
U53588 | protein phosphatase 1, regulatory (inhibitor) subunit 11 | PPP1R11 | 9_11 | 0.024342692 | decreased | 1.230500031962777 | 38412_at | 606670 | ENSG00000112498 | 82887 | 6992 | NM_021959 /// NM_170781 |  | --- | protein phosphatase inhibitor activity | soluble fraction | --- | ---
U05340 | CDC20 cell division cycle 20 homolog (S. cerevisiae) | CDC20 | 8_10 | 0.00556549 | decreased | 1.962040734918338 | 38414_at | 603618 | ENSG00000117399 | 524947 | 991 | NM_001255 |  | regulation of cell cycle /// cytokinesis /// ubiquitin-dependent protein catabolism /// ubiquitin cycle /// mitosis | --- | spindle | [NAME] | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm
U09759 | mitogen-activated protein kinase 9 | MAPK9 | 9_11 | 0.014337793 | decreased | 1.731392645211236 | 38431_at | 602896 | ENSG00000050748 | 484371 | 5601 | NM_002752 /// NM_139068 /// NM_139069 /// NM_139070 |  | protein amino acid phosphorylation /// response to stress /// JNK cascade | protein serine/threonine kinase activity /// JUN kinase activity /// MAP kinase activity /// protein binding /// ATP binding /// transferase activity | --- | TGF_Beta_Signaling_Pathway /// Wnt_signaling | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_TGF_Beta_Signaling_Pathway/Hs_TGF_Beta_Signaling_Pathway.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm
AA015605 | armadillo repeat containing, X-linked 6 | ARMCX6 | 9_11 | 0.02452532 | decreased | 1.580170547980854 | 38440_s_at | --- | ENSG00000198960 | 83530 | 54470 | NM_001009584 /// NM_019007 |  | --- | --- | --- | --- | ---
L39945 | cytochrome b-5 | CYB5 | 6_10 | 0.012766987 | decreased | 1.589179955187422 | 38458_at | 250790 | ENSG00000166347 | 465413 | 1528 | NM_001914 /// NM_148923 |  | electron transport /// transport | cytochrome-c oxidase activity | mitochondrion /// endoplasmic reticulum /// microsome /// integral to membrane | --- | ---
M22976 | cytochrome b-5 | CYB5 | 8_10 | 0.004729737 | decreased | 2.29674894936074 | 38460_at | 250790 | ENSG00000166347 | 465413 | 1528 | NM_001914 /// NM_148923 |  | electron transport /// transport | cytochrome-c oxidase activity | mitochondrion /// endoplasmic reticulum /// microsome /// integral to membrane | --- | ---
U65676 | Hermansky-Pudlak syndrome 1 | HPS1 | 1_5 | 0.035054242 | increased | 1.756792978458126 | 38468_at | 203300 /// 604982 | ENSG00000107521 | 404568 | 3257 | NM_000195 /// NM_182637 /// NM_182638 /// NM_182639 |  | --- | --- | --- | --- | ---
AI984786 | B-cell receptor-associated protein 29 | BCAP29 | 2_10 | 0.03031408 | decreased | 1.688675773248135 | 38552_f_at | --- | ENSG00000075790 | 303787 | 55973 | NM_001008405 /// NM_001008406 /// NM_001008407 /// NM_018844 |  | intracellular protein transport /// apoptosis | --- | endoplasmic reticulum /// integral to membrane | --- | ---
AF039652 | ribonuclease H1 | RNASEH1 | 3_11 | 0.023508279 | decreased | 1.721378211406008 | 38563_at | 604123 | ENSG00000171865 | 502765 | 246243 | NM_002936 |  | RNA catabolism | magnesium ion binding /// [NAME] binding /// endonuclease activity /// ribonuclease H activity /// ribonuclease activity /// hydrolase activity | --- | --- | ---
D45906 | LIM domain kinase 2 | [NAME] | 5_2 | 0.015611491 | increased | 2.42878346244317 | 38617_at | 601988 | ENSG00000182541 | 474596 | 3985 | NM_005569 /// NM_016733 |  | protein amino acid phosphorylation | protein serine/threonine kinase activity /// protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// protein binding /// ATP binding /// zinc ion binding /// transferase activity | nucleus /// cytoplasm | --- | ---
M95585 | Hepatic leukemia factor | HLF | 7_3 | 0.002558913 | increased | 1.634844993656788 | 38627_at | 142385 | ENSG00000108924 | 196952 | 3131 | NM_002126 |  | transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// development /// rhythmic process | double-stranded DNA binding | nucleus | --- | ---
AB009285 | craniofacial development protein 1 | CFDP1 | 9_11 | 0.029175216 | decreased | 2.474448170657316 | 38664_at | 608108 | ENSG00000153774 | 461361 | 10428 | NM_006324 |  | --- | --- | --- | --- | ---
AB002804 | --- | --- | 9_11 | 0.019533331 | decreased | 1.684292925634076 | 38669_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
U94175 | eukaryotic translation initiation factor 3, subunit 6 48kDa | EIF3S6 | 9_11 | 0.018979463 | decreased | 1.859132045940489 | 38681_at | 602210 | ENSG00000104408 | 405590 | 3646 | NM_001568 |  | protein biosynthesis | translation initiation factor activity | --- | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
AF045451 | NGFI-A binding protein 1 (EGR1 binding protein 1) | NAB1 | 4_10 | 0.008579743 | decreased | 2.22227946234689 | 38692_at | 600800 | ENSG00000138386 | 107474 | 4664 | NM_005966 |  | transcription /// regulation of transcription, DNA-dependent /// negative regulation of transcription | nucleic acid binding /// transcriptional repressor activity /// transcriptional repressor activity | nucleus /// nucleus | --- | ---
AB018330 | calcium/calmodulin-dependent protein kinase kinase 2, beta | CAMKK2 | 9_11 | 0.021619221 | decreased | 1.46090462018968 | 38716_at | --- | ENSG00000110931 | 297343 | 10645 | NM_006549 /// NM_153499 /// NM_153500 /// NM_172214 /// NM_172215 /// NM_172216 /// NM_172226 |  | MAPKKK cascade /// calcium-mediated signaling /// regulation of protein kinase activity /// positive regulation of transcription /// autophosphorylation | protein serine/threonine kinase activity /// calcium- and calmodulin-dependent protein kinase activity /// calcium- and calmodulin-dependent protein kinase activity /// protein-tyrosine kinase activity /// calcium ion binding /// calmodulin binding /// ATP binding /// transferase activity | intracellular | --- | ---
AL050159 | DKFZP586A0522 protein | DKFZP586A0522 | 9_11 | 0.022889256 | decreased | 1.541465994130908 | 38717_at | --- | ENSG00000185432 | 288771 | 25840 | NM_014033 |  | --- | S-adenosylmethionine-dependent methyltransferase activity /// transferase activity | --- | --- | ---
N36295 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit | DPM2 | 1_3 | 0.001535352 | increased | 2.513917879521778 | 38725_s_at | 603564 | ENSG00000136908 | 108973 | 8818 | NM_003863 /// NM_152690 |  | protein amino acid glycosylation /// macromolecule biosynthesis | transferase activity, transferring glycosyl groups | endoplasmic reticulum membrane /// integral to membrane /// integral to endoplasmic reticulum membrane | --- | ---
U90546 | butyrophilin, subfamily 3, member A2 | BTN3A2 | 4_11 | 0.025922841 | decreased | 2.995896915209678 | 38760_f_at | --- | ENSG00000186470 | 376046 | 11118 | NM_007047 |  | --- | receptor activity | integral to membrane /// integral to membrane | --- | ---
L29254 | sorbitol dehydrogenase | SORD | 3_10 | 0.035172173 | decreased | 3.547430143019676 | 38763_at | 182500 | ENSG00000140263 | 878 | 6652 | NM_003104 |  | sorbitol metabolism /// visual perception | L-iditol 2-dehydrogenase activity /// zinc ion binding /// oxidoreductase activity | --- | Fructose and mannose metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00051+1.1.1.14
L25879 | epoxide hydrolase 1, microsomal (xenobiotic) | EPHX1 | 9_11 | 0.03398088 | decreased | 1.0896443583074 | 38790_at | 132810 | ENSG00000143819 | 89649 | 2052 | NM_000120 |  | xenobiotic metabolism /// response to toxin /// aromatic compound catabolism | epoxide hydrolase activity /// hydrolase activity | endoplasmic reticulum /// microsome /// membrane /// integral to membrane | Tetrachloroethene degradation | www.genome.ad.jp/dbget-bin/show_pathway?MAP00625+3.3.2.3
X56687 | upstream binding transcription factor, [NAME] polymerase I | UBTF | 9_11 | 0.014007134 | decreased | 2.40804695974549 | 38795_s_at | 600673 | ENSG00000108312 | 89781 | 7343 | NM_014233 |  | transcription /// regulation of transcription, DNA-dependent /// regulation of transcription from RNA polymerase I promoter | DNA binding /// [NAME] polymerase I transcription factor activity | nucleus /// nucleolus | --- | ---
X75621 | tuberous sclerosis 2 | TSC2 | 4_11 | 0.011215904 | decreased | 1.89360889121709 | 38813_at | 191092 /// 191100 /// 606690 | ENSG00000103197 | 90303 | 7249 | NM_000548 /// NM_021055 /// NM_021056 |  | protein folding /// endocytosis /// negative regulation of cell cycle | GTPase activator activity /// unfolded protein binding | membrane fraction /// cytosol /// plasma membrane | --- | ---
U66685 | ATP-binding cassette, sub-family F (GCN20), member 3 | ABCF3 | 8_10 | 0.02789992 | decreased | 1.198353893521058 | 38830_at | --- | ENSG00000161204 | 361323 | 55324 | NM_018358 |  | --- | --- | --- | --- | ---
AF068195 | ubiquitin associated domain containing 1 | UBADC1 | 4_11 | 0.026723611 | decreased | 1.845292334448386 | 38841_at | 608129 | ENSG00000130560 | 9194 | 10422 | NM_016172 |  | --- | --- | nucleus | --- | ---
AA768912 | single-stranded DNA binding protein 1 | SSBP1 | 9_11 | 0.005388551 | decreased | 1.924492044096677 | 38846_at | 600439 | ENSG00000106028 | 490394 | 6742 | NM_003143 |  | DNA replication | single-stranded DNA binding | mitochondrion | --- | ---
D79989 | centaurin, gamma 1 | CENTG1 | 2_10 | 0.034816257 | decreased | 2.077380743455144 | 38852_at | 605476 | ENSG00000135439 | 302435 | 116986 | NM_014770 |  | signal transduction /// small GTPase mediated signal transduction /// regulation of GTPase activity | GTPase activity /// GTPase activator activity /// GTP binding /// kinase activity | nucleus | --- | ---
W26851 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein | NFATC2IP | 3_10 | 0.006550815 | decreased | 1.795359548205199 | 38864_at | --- | ENSG00000176953 | 513470 | 84901 | NM_032815 |  | protein modification | --- | --- | --- | ---
X77094 | neutrophil cytosolic factor 4, 40kDa | NCF4 | 10_10 | 0.013888529 | decreased | 1.462178081397153 | 38895_i_at | 601488 | ENSG00000100365 | 474781 | 4689 | NM_000631 /// NM_013416 |  | electron transport /// defense response /// intracellular signaling cascade | electron transporter activity | [NAME] | --- | ---
AL096744 | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | REV3L | 9_11 | 0.01148732 | decreased | 1.921762553723795 | 38908_s_at | 602776 | ENSG00000009413 | 232021 | 5980 | NM_002912 |  | DNA replication /// DNA-dependent DNA replication /// DNA repair | nucleotide binding /// DNA binding /// DNA-directed DNA polymerase activity /// zeta DNA polymerase activity /// 3'-5' exonuclease activity /// transferase activity | nucleus /// zeta DNA polymerase complex | --- | ---
AJ011896 | TNFAIP3 interacting protein 1 | TNIP1 | 7_3 | 0.02766554 | increased | 1.564385332556384 | 38971_r_at | 607714 | ENSG00000145901 | 355141 | 10318 | NM_006058 |  | defense response /// glycoprotein biosynthesis /// pathogenesis /// negative regulation of viral genome replication | protein binding | nucleus | --- | ---
AA203354 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa | NDUFB3 | 9_11 | 0.006846439 | decreased | 2.01547034358651 | 38981_at | 603839 | ENSG00000119013 | 109760 | 4709 | NM_002491 |  | mitochondrial electron transport, NADH to ubiquinone | NADH dehydrogenase activity /// NADH dehydrogenase (ubiquinone) activity /// oxidoreductase activity | mitochondrion | Electron_Transport_Chain | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm
AF043324 | N-myristoyltransferase 1 | NMT1 | 9_11 | 0.00631789 | decreased | 1.813488308784808 | 39000_at | 160993 | ENSG00000136448 | 532790 | 4836 | NM_021079 |  | N-terminal protein lipidation /// N-terminal protein myristoylation /// protein-lipoylation | glycylpeptide N-tetradecanoyltransferase activity /// acyltransferase activity /// transferase activity | --- | --- | ---
AF047470 | malate dehydrogenase 2, NAD (mitochondrial) | MDH2 | 8_10 | 0.007955276 | decreased | 1.892747511847859 | 39001_at | 154100 | ENSG00000146701 | 520967 | 4191 | NM_005918 |  | glycolysis /// tricarboxylic acid cycle /// malate metabolism | L-lactate dehydrogenase activity /// oxidoreductase activity /// L-malate dehydrogenase activity | mitochondrial matrix | Glycolysis_and_Gluconeogenesis /// Krebs-TCA_Cycle /// Citrate cycle (TCA cycle) /// Pyruvate metabolism /// Glyoxylate and dicarboxylate metabolism /// Carbon fixation /// Reductive carboxylate cycle (CO2 fixation) | [NAME] /// www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Krebs-TCA_Cycle/Hs_Krebs-TCA_Cycle.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00020+1.1.1.37 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00620+1.1.1.37 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00630+1.1.1.37 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00710+1.1.1.37 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00720+1.1.1.37
AF053944 | AE binding protein 1 | AEBP1 | 1_1 | 0.002656991 | increased | 2.011131995972961 | 39069_at | 602981 | ENSG00000106624 | 439463 | 165 | NM_001129 |  | skeletal development /// proteolysis and peptidolysis /// cell adhesion /// muscle development | transcription factor activity /// carboxypeptidase activity /// carboxypeptidase A activity | cytoplasm | --- | ---
AB022718 | chromosome 10 open reading frame 10 | C10orf10 | 5_6 | 0.01595895 | increased | 2.703784774206582 | 39114_at | --- | ENSG00000165507 | 93675 | 11067 | NM_007021 |  | --- | --- | --- | --- | ---
N36842 | [NAME] regulator of nonsense transcripts homolog A (yeast) | UPF3A | 9_11 | 0.021562706 | decreased | 1.65833012005088 | 39131_at | 605530 | ENSG00000169062 | 514737 | 65110 | NM_023011 /// NM_080687 |  | mRNA catabolism, nonsense-mediated decay /// mRNA processing /// mRNA-nucleus export /// transport | nucleotide binding /// [NAME] binding /// nucleocytoplasmic transporter activity | nucleus /// cytoplasm | --- | ---
U47101 | NifU-like N-terminal domain containing | NIFUN | 9_11 | 0.01225286 | decreased | 1.732815442737696 | 39165_at | --- | ENSG00000136003 | 350702 | 23479 | NM_014301 /// NM_213595 |  | nitrogen fixation /// iron-sulfur cluster assembly | iron ion binding | nucleus /// mitochondrion | --- | ---
U00928 | --- | --- | 7_3 | 0.023784633 | increased | 1.489435189191586 | 39181_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
X66363 | PCTAIRE protein kinase 1 | PCTK1 | 1_3 | 0.022742352 | increased | 1.003252469422317 | 39183_at | 311550 | ENSG00000102225 | 496068 | 5127 | NM_006201 /// NM_033018 |  | regulation of cell cycle /// protein amino acid phosphorylation /// protein amino acid phosphorylation | protein serine/threonine kinase activity /// protein serine/threonine kinase activity /// ATP binding /// transferase activity | --- | Phosphatidylinositol signaling system | www.genome.ad.jp/dbget-bin/show_pathway?MAP04070+2.7.1.37
X17406 | aggrecan 1 (chondroitin sulfate proteoglycan 1, large aggregating proteoglycan, antigen identified by monoclonal antibody A0122) | AGC1 | 3_10 | 0.033213679 | decreased | 2.17317976004261 | 39207_r_at | 155760 | ENSG00000157766 | 2159 | 176 | NM_001135 /// NM_013227 |  | cell adhesion | sugar binding /// hyaluronic acid binding | --- | --- | ---
U52111 | plexin B3 | PLXNB3 | 6_10 | 0.005745127 | decreased | 2.067684764319106 | 39214_at | 300214 | ENSG00000198753 | 380742 | 5365 | NM_005393 |  | development | receptor activity | membrane /// integral to membrane | --- | ---
AB011152 | centaurin, delta 1 | CENTD1 | 8_10 | 0.007013155 | decreased | 1.448318012288973 | 39224_at | 606645 | ENSG00000047365 | 479451 | 116984 | NM_015230 /// NM_139182 |  | signal transduction /// regulation of GTPase activity | --- | --- | --- | ---
AL022318 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | APOBEC3B | 1_3 | 0.007282704 | increased | 1.948670463060141 | 39230_at | 607110 | ENSG00000179750 | 226307 | 9582 | NM_004900 |  | --- | zinc ion binding /// hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines | --- | --- | ---
M87434 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | OAS2 | 1_3 | 0.01276995 | increased | 1.389972522589415 | 39263_at | 603350 | ENSG00000111335 | 414332 | 4939 | NM_002535 /// NM_016817 |  | nucleobase, nucleoside, nucleotide and nucleic acid metabolism /// immune response | RNA binding /// ATP binding /// transferase activity /// nucleotidyltransferase activity | microsome /// membrane | --- | ---
AB023188 | KIAA0971 | KIAA0971 | 2_8 | 0.029847748 | decreased | 3.742388419189059 | 39299_at | --- | ENSG00000118246 | 84429 | 22868 | NM_014929 |  | apoptosis | protein kinase activity /// ATP binding | --- | --- | ---
X82240 | T-cell leukemia/lymphoma 1A | TCL1A | 7_3 | 0.002617969 | increased | 1.624105849092113 | 39318_at | 186960 | ENSG00000100721 | 2484 | 8115 | NM_021966 |  | development | --- | endoplasmic reticulum /// microsome | --- | ---
Z71460 | ATPase, H+ transporting, lysosomal V0 subunit a isoform 1 | ATP6V0A1 | 5_2 | 0.006425969 | increased | 1.845696326227651 | 39326_at | 192130 | ENSG00000033627 | 463074 | 535 | NM_005177 |  | ion transport /// proton transport | hydrogen ion transporter activity | membrane /// integral to membrane | Oxidative phosphorylation /// ATP synthesis /// Photosynthesis /// [NAME] assembly /// Type III secretion system | www.genome.ad.jp/dbget-bin/show_pathway?MAP00190+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00193+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00195+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP02040+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03070+3.6.3.14
X99209 | HMT1 hnRNP methyltransferase-like 1 (S. cerevisiae) | HRMT1L1 | 9_11 | 0.011713491 | decreased | 1.618861234803879 | 39348_at | 601961 | ENSG00000160310 | 154163 | 3275 | NM_001535 /// NM_206962 |  | protein amino acid methylation /// signal transduction | signal transducer activity /// S-adenosylmethionine-dependent methyltransferase activity /// transferase activity | nucleus | --- | ---
U34044 | Selenophosphate synthetase 1 | SEPHS1 | 6_10 | 0.004552561 | decreased | 2.073570263296282 | 39387_at | 600902 | ENSG00000086475 | 124027 | 22929 | NM_012247 |  | protein modification | selenide, water dikinase activity /// ATP binding /// GTP binding /// transferase activity | --- | Selenoamino acid metabolism | [NAME]
AF055581 | lymphocyte adaptor protein | LNK | 4_11 | 0.031851575 | decreased | 1.505354161244885 | 39428_at | 605093 | ENSG00000111252 | 506784 | 10019 | [NAME] |  | intracellular signaling cascade | --- | --- | --- | ---
AA457029 | Inositol polyphosphate-4-phosphatase, type I, 107kDa | INPP4A | 5_2 | 0.033538552 | increased | 2.257002045943617 | 39512_s_at | 600916 | ENSG00000040933 | 469386 | 3631 | NM_001566 /// NM_004027 |  | signal transduction | --- | --- | Inositol phosphate metabolism /// Phosphatidylinositol signaling system | www.genome.ad.jp/dbget-bin/show_pathway?MAP00562+3.1.3.66 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP04070+3.1.3.66
AI625844 | hypothetical protein LOC201229 | LOC201229 | 2_11 | 0.021109419 | decreased | 2.036530837862689 | 39557_at | --- | --- | 434386 | 201229 | XM_375430 |  | --- | --- | --- | --- | ---
W28989 | calmodulin regulated spectrin-associated protein 1 | CAMSAP1 | 8_10 | 0.004459342 | decreased | 1.286663912937644 | 39571_at | --- | ENSG00000130559 | 522493 | 157922 | NM_015447 |  | --- | --- | --- | --- | ---
AB018345 | [NAME] | [NAME] | 5_2 | 0.024971328 | increased | 2.128881715441746 | 39614_at | --- | ENSG00000168502 | 464563 | 23255 | NM_015210 |  | --- | --- | --- | --- | ---
AB017168 | slit homolog 2 (Drosophila) | SLIT2 | 4_11 | 0.031426978 | decreased | 1.894697989715564 | 39634_at | 603746 | ENSG00000145147 | 29802 | 9353 | NM_004787 |  | ureteric bud development /// chemotaxis /// cell adhesion /// G-protein coupled receptor protein signaling pathway /// neurogenesis /// mesoderm migration /// sensory perception /// perception of smell /// neuronal cell recognition /// motor axon guidance /// glia cell migration /// cell differentiation /// positive regulation of axonogenesis /// induction of negative chemotaxis /// induction of negative chemotaxis | follicle stimulating hormone receptor activity /// receptor binding /// structural molecule activity /// calcium ion binding /// protein binding | extracellular space /// integral to membrane | --- | ---
U94703 | polymerase (DNA directed), gamma 2, accessory subunit | POLG2 | 1_3 | 0.008607727 | increased | 2.209976436607062 | 39643_at | 604983 | ENSG00000136480 | 437009 | 11232 | NM_007215 |  | DNA-dependent DNA replication /// DNA repair /// protein biosynthesis /// glycyl-tRNA aminoacylation /// proteolysis and peptidolysis | single-stranded DNA binding /// gamma DNA-directed DNA polymerase activity /// tRNA ligase activity /// glycine-tRNA ligase activity /// ATP binding /// metallopeptidase activity /// zinc ion binding /// transferase activity | mitochondrial chromosome /// mitochondrion | --- | ---
S60415 | calcium channel, voltage-dependent, beta 2 subunit | CACNB2 | 9_11 | 0.002483421 | decreased | 1.765568856479508 | 39646_at | 600003 | ENSG00000165995 | 59093 | 783 | NM_000724 /// NM_201570 /// NM_201571 /// NM_201572 /// NM_201590 /// NM_201593 /// NM_201596 /// NM_201597 |  | ion transport /// calcium ion transport /// calcium ion transport /// neuromuscular junction development | voltage-gated calcium channel activity /// voltage-gated calcium channel activity | membrane fraction /// voltage-gated calcium channel complex | --- | ---
AF034102 | solute carrier family 29 (nucleoside transporters), member 2 | SLC29A2 | 6_10 | 0.025507203 | decreased | 1.826405587366024 | 39661_s_at | 602110 | ENSG00000174669 | 32951 | 3177 | NM_001532 |  | nucleobase, nucleoside, nucleotide and nucleic acid metabolism /// transport /// cell proliferation /// nucleoside transport | nucleoside transporter activity /// nucleoside transporter activity | nucleolus /// integral to plasma membrane /// membrane | --- | ---
X95694 | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) | TFAP2B | 6_11 | 0.001990503 | decreased | 1.600423320308444 | 39668_at | 169100 /// 601601 | ENSG00000008196 | 33102 | 7021 | NM_003221 |  | transcription /// regulation of transcription from RNA polymerase II promoter /// neurogenesis | transcription factor activity /// transcription coactivator activity | nucleus | --- | ---
AB011792 | extracellular matrix protein 2, female organ and [NAME] specific | ECM2 | 9_11 | 0.011624329 | decreased | 1.557553975894762 | 39673_i_at | 603479 | ENSG00000106823 | 117060 | 1842 | NM_001393 |  | cell-matrix adhesion | [NAME] /// structural molecule activity | extracellular matrix ([NAME]) | --- | ---
AL050282 | ataxin 10 | ATXN10 | 9_11 | 0.033165024 | decreased | 1.770083492629306 | 39686_g_at | 603516 | ENSG00000130638 | 475125 | 25814 | NM_013236 |  | --- | binding | --- | --- | ---
AF007157 | prion protein interacting protein | PRNPIP | 2_11 | 0.016216217 | decreased | 2.352432084758786 | 39772_at | --- | ENSG00000117419 | 132497 | 79033 | XM_290941 |  | --- | exonuclease activity /// hydrolase activity | nucleus | --- | ---
M55621 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | MGAT1 | 5_2 | 0.035278368 | increased | 1.483455626909225 | 39778_at | 160995 | ENSG00000131446 | 519818 | 4245 | NM_002406 |  | carbohydrate metabolism /// aminoglycan biosynthesis /// N-linked glycosylation | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity /// transferase activity, transferring glycosyl groups | Golgi membrane /// integral to membrane | N-Glycan biosynthesis | www.genome.ad.jp/dbget-bin/show_pathway?MAP00510+2.4.1.101
U25147 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | SLC25A1 | 9_11 | 0.007921345 | decreased | 1.87488132871368 | 39825_at | 190315 | ENSG00000100075 | 111024 | 6576 | NM_005984 |  | transport /// mitochondrial citrate transport | transporter activity /// binding /// citrate transporter activity | mitochondrion /// mitochondrial inner membrane /// integral to membrane | Fatty_Acid_Synthesis | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Fatty_Acid_Synthesis/Hs_Fatty_Acid_Synthesis.htm
AA528252 | vitamin K epoxide reductase complex, subunit 1 | [NAME] | 1_5 | 0.010849982 | increased | 1.5417040972381 | 39862_at | 122700 /// 607473 /// 608547 | ENSG00000167397 | 324844 | 79001 | NM_024006 /// NM_206824 |  | negative regulation of blood coagulation | oxidoreductase activity /// vitamin-K-epoxide reductase (warfarin-sensitive) activity | endoplasmic reticulum /// integral to membrane | Biosynthesis of steroids | [NAME]
AI769085 | --- | --- | 2_7 | 0.028144525 | decreased | 2.149237645253152 | 39902_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
D21337 | collagen, type IV, alpha 6 | COL4A6 | 9_11 | 0.020372191 | decreased | 2.702095995569306 | 39939_at | 303631 /// 308940 | ENSG00000197565 | 145586 | 1288 | NM_001847 /// NM_033641 |  | phosphate transport /// cell adhesion /// extracellular matrix organization and biogenesis | extracellular matrix structural constituent /// extracellular matrix structural constituent /// protein binding | [NAME] /// collagen type IV /// basement membrane /// cytoplasm | --- | ---
AB019527 | [NAME], down-regulated in cancer 1 | LDOC1 | 9_11 | 0.017621327 | decreased | 1.368725140546314 | 39967_at | 300402 | ENSG00000182195 | 45231 | 23641 | NM_012317 |  | negative regulation of cell proliferation | --- | nucleus | --- | ---
AL022395 | F-box and leucine-rich repeat protein 4 | FBXL4 | 8_10 | 0.02153088 | decreased | 1.776547328364457 | 39987_at | 605654 | ENSG00000112234 | 536850 | 26235 | NM_012160 |  | ubiquitin-dependent protein catabolism /// ubiquitin cycle | --- | ubiquitin ligase complex /// nucleus | --- | ---
X60201 | brain-derived neurotrophic factor | BDNF | 5_2 | 0.013333167 | increased | 2.209607927613505 | 40023_at | 113505 /// 164230 /// 209880 | ENSG00000176697 | 502182 | 627 | NM_001709 /// NM_170731 /// NM_170732 /// NM_170733 /// NM_170734 /// NM_170735 |  | neurogenesis | growth factor activity /// growth factor activity | --- | --- | ---
W52999 | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (factor B) | ATP5S | 8_10 | 0.027028536 | decreased | 1.211718693775915 | 40027_at | --- | ENSG00000125375 | 438489 | 27109 | NM_001003803 /// NM_001003805 /// NM_015684 |  | ion transport /// proton transport /// proton transport | hydrogen ion transporter activity /// hydrogen ion transporter activity | mitochondrion | Electron_Transport_Chain | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm
U94777 | phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) | PYGM | 8_10 | 0.021775347 | decreased | 1.002919600517349 | 40057_at | 232600 /// 608455 | ENSG00000068976 | 154084 | 5837 | NM_005609 |  | carbohydrate metabolism /// glycogen metabolism | glycogen phosphorylase activity /// transferase activity, transferring glycosyl groups | --- | Glycogen_Metabolism /// Starch and sucrose metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Glycogen_Metabolism/Hs_Glycogen_Metabolism.htm /// [NAME]
Z48054 | peroxisomal biogenesis factor 5 | PEX5 | 6_11 | 0.030545847 | decreased | 1.747478131075207 | 40151_s_at | 202370 /// 214100 /// 600414 | ENSG00000139197 | 479944 | 5830 | NM_000319 |  | protein transport | peroxisome targeting signal-1 receptor activity /// binding | peroxisomal membrane | --- | ---
X05451 | [NAME], light polypeptide 1, alkali; skeletal, fast | MYL1 | 6_10 | 0.022481626 | decreased | 1.478530749458737 | 40157_s_at | 160780 | ENSG00000168530 | 187338 | 4632 | NM_079420 /// NM_079422 |  | muscle development | motor activity /// calcium ion binding /// structural constituent of muscle | [NAME] /// [NAME] | G13_Signaling_Pathway /// Striated_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G13_Signaling_Pathway/Hs_G13_Signaling_Pathway.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Striated_muscle_contraction/Hs_Striated_muscle_contraction.htm
L37042 | casein kinase 1, alpha 1 | CSNK1A1 | 4_11 | 0.013399629 | decreased | 2.566491297915166 | 40184_at | 600505 | ENSG00000113712 | 442592 | 1452 | NM_001892 |  | protein amino acid phosphorylation /// protein amino acid phosphorylation /// Wnt receptor signaling pathway | protein serine/threonine kinase activity /// casein kinase I activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity | --- | --- | ---
M93651 | SET translocation (myeloid leukemia-associated) | SET | 9_11 | 0.030265684 | decreased | 1.290053665882185 | 40189_at | 600960 | ENSG00000119335 | 436687 | 6418 | NM_003011 |  | DNA replication /// nucleosome assembly /// nucleosome disassembly /// nucleocytoplasmic transport /// negative regulation of histone acetylation | protein phosphatase inhibitor activity /// protein phosphatase type 2A regulator activity /// histone binding | nucleus /// endoplasmic reticulum /// perinuclear region | --- | ---
AI761647 | [NAME] | [NAME] | 9_11 | 0.024546841 | decreased | 1.416881780191269 | 40191_s_at | --- | ENSG00000011523 | 146007 | 23177 | NM_015147 |  | --- | --- | --- | --- | ---
U00943 | --- | --- | 7_3 | 0.016658165 | increased | 1.540103754230611 | 40252_g_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AI703188 | G protein-coupled receptor 161 | GPR161 | 9_11 | 0.0314819 | decreased | 1.825863429386218 | 40301_at | --- | ENSG00000143147 | 271809 | 23432 | NM_007369 /// NM_153832 |  | signal transduction /// G-protein coupled receptor protein signaling pathway | rhodopsin-like receptor activity /// receptor activity | integral to membrane | GPCRDB_Class_A_Rhodopsin-like2 | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like2/Hs_GPCRDB_Class_A_Rhodopsin-like2.htm
M57609 | GLI-Kruppel family member [NAME] ([NAME] cephalopolysyndactyly syndrome) | GLI3 | 4_11 | 0.008291407 | decreased | 2.5218520890531 | 40358_at | 146510 /// 165240 /// 174200 /// 174700 /// 175700 /// 200990 | ENSG00000106571 | 199338 | 2737 | NM_000168 |  | protein-nucleus import, translocation /// transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// signal transduction /// morphogenesis | transcription factor activity /// catalytic activity /// zinc ion binding | nucleus /// cytoplasm | --- | ---
D87436 | lipin 2 | LPIN2 | 8_10 | 0.014993517 | decreased | 1.632138094184917 | 40447_at | 605519 | ENSG00000101577 | 268581 | 9663 | NM_014646 |  | --- | --- | nucleus | --- | ---
AF038250 | splicing factor, arginine/serine-rich 3 | SFRS3 | 2_10 | 0.027620823 | decreased | 0.7513594875033166 | 40457_at | 603364 | ENSG00000112081 | 405144 | 6428 | NM_003017 |  | nuclear mRNA splicing, via spliceosome | nucleic acid binding /// RNA binding | nucleus | --- | ---
K03195 | solute carrier family 2 (facilitated glucose transporter), member 1 | SLC2A1 | 5_2 | 0.025738071 | increased | 2.690657368214951 | 40507_at | 138140 /// 606777 | ENSG00000117394 | 473721 | 6513 | NM_006516 |  | carbohydrate transport /// glucose transport | transporter activity /// sugar porter activity /// glucose transporter activity | membrane fraction /// membrane /// integral to membrane | --- | ---
AF025887 | glutathione S-transferase A4 | GSTA4 | 8_10 | 0.026661593 | decreased | 1.101107161029887 | 40508_at | 605450 | ENSG00000170899 | 485557 | 2941 | NM_001512 |  | response to stress /// metabolism | glutathione transferase activity /// transferase activity | --- | Glutathione metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00480+2.5.1.18
U61843 | discs, large homolog 5 (Drosophila) | DLG5 | 8_10 | 0.013782831 | decreased | 1.427989066698399 | 40575_at | 604090 | ENSG00000151208 | 500245 | 9231 | NM_004747 |  | regulation of cell cycle /// intracellular signaling cascade /// negative regulation of cell proliferation /// cell-cell adhesion | protein binding /// receptor signaling complex scaffold activity | cytoplasm /// plasma membrane | --- | ---
AL096740 | ubiquitin protein ligase E3B | UBE3B | 7_3 | 0.03455603 | increased | 1.632171921763846 | 40622_r_at | 608047 | ENSG00000151148 | 374067 | 89910 | NM_130466 /// NM_183414 /// NM_183415 |  | ubiquitin cycle | ubiquitin-protein ligase activity | intracellular | --- | ---
AJ223280 | linker for activation of T cells | LAT | 4_11 | 0.002446678 | decreased | 2.267960484149776 | 40688_at | 602354 | ENSG00000169678 | 498997 | 27040 | NM_001014987 /// NM_001014988 /// NM_001014989 /// NM_014387 |  | immune response /// integrin-mediated signaling pathway /// intracellular signaling cascade /// [NAME] protein signal transduction /// calcium-mediated signaling /// regulation of T-cell activation | SH3/SH2 adaptor activity /// protein binding /// protein binding | immunological synapse /// membrane /// integral to membrane /// lipid raft | --- | ---
U75362 | ubiquitin specific protease 13 (isopeptidase T-3) | USP13 | 4_11 | 0.011963056 | decreased | 1.9765045615723 | 40701_at | 603591 | ENSG00000058056 | 175322 | 8975 | NM_003940 |  | ubiquitin-dependent protein catabolism /// ubiquitin cycle | cysteine-type endopeptidase activity /// ubiquitin thiolesterase activity | --- | --- | ---
S82198 | chymotrypsin C (caldecrin) | CTRC | 2_9 | 0.010025658 | decreased | 2.526652158384601 | 40714_at | 601405 | ENSG00000162438 | 8709 | 11330 | NM_007272 |  | proteolysis and peptidolysis | chymotrypsin activity /// trypsin activity /// peptidase activity | --- | --- | ---
AB001928 | [NAME] | CTSL2 | 1_3 | 0.028611462 | increased | 1.703685274262966 | 40717_at | 603308 | ENSG00000136943 | 87417 | 1515 | NM_001333 |  | proteolysis and peptidolysis | cathepsin L activity | lysosome | --- | ---
U37426 | [NAME] member 11 | KIF11 | 8_10 | 0.031759783 | decreased | 1.216138446979042 | 40726_at | 148760 | ENSG00000138160 | 8878 | 3832 | NM_004523 |  | cytokinesis /// microtubule-based movement /// cell cycle /// mitotic spindle organization and biogenesis | microtubule motor activity /// ATP binding | spindle /// kinesin complex | --- | ---
L13939 | adaptor-related protein complex 1, beta 1 subunit | AP1B1 | 1_6 | 0.034934288 | increased | 1.143523685026335 | 40745_at | 600157 | ENSG00000100280 | 368794 | 162 | NM_001127 /// NM_145730 |  | protein complex assembly /// intracellular protein transport /// endocytosis | transporter activity /// binding /// protein binding | Golgi apparatus /// coated pit /// clathrin coat of trans-Golgi network vesicle | --- | ---
U85707 | [NAME], myeloid ecotropic viral integration site 1 homolog (mouse) | [NAME] | 9_11 | 0.020819515 | decreased | 2.605490571344449 | 40763_at | 601739 | ENSG00000143995 | 526754 | 4211 | NM_002398 |  | regulation of transcription, DNA-dependent | transcription factor activity /// RNA polymerase II transcription factor activity | nucleus | --- | ---
X64228 | nucleoporin 214kDa | NUP214 | 3_9 | 0.005218309 | decreased | 1.765961913932924 | 40768_s_at | 114350 /// 601626 | ENSG00000126883 | 461860 | 8021 | NM_005085 |  | transport | transporter activity /// porin activity | nucleus /// nuclear pore /// integral to membrane /// outer membrane | --- | ---
T53900 | chromosome 16 open reading frame 34 | C16orf34 | 1_6 | 0.033759682 | increased | 1.646415292079047 | 40799_at | --- | ENSG00000007545 | 513261 | 90861 | NM_144570 |  | regulation of transcription, DNA-dependent | DNA binding | nucleus | --- | ---
[NAME] | pregnancy specific beta-1-glycoprotein 3 | PSG3 | 1_5 | 0.024312748 | increased | 1.950094652817567 | 40857_f_at | 176392 | ENSG00000189231 | 466843 | 5671 | NM_021016 |  | defense response /// pregnancy /// pregnancy | --- | extracellular region | --- | ---
[NAME] | Solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | SLC6A8 | 7_3 | 0.016018079 | increased | 1.123462059302608 | 40927_at | 300036 /// 300352 /// 300397 | ENSG00000130821 | 540696 | 6535 | NM_005629 |  | neurotransmitter uptake /// ion transport /// sodium ion transport /// neurotransmitter transport /// muscle contraction | creatine:sodium symporter activity /// neurotransmitter:sodium symporter activity /// symporter activity | integral to plasma membrane /// membrane | --- | ---
AI023044 | Hypothetical protein FLJ12671 | FLJ12671 | 6_10 | 0.00188738 | decreased | 1.655312033453836 | 40946_at | --- | ENSG00000143319 | 301904 | 81875 | NM_030980 |  | --- | exonuclease activity /// hydrolase activity | nucleus | --- | ---
X05608 | neurofilament, light polypeptide 68kDa | NEFL | 2_11 | 0.008414995 | decreased | 1.536708556409965 | 40995_at | 162280 /// 607684 /// 607734 | ENSG00000104725 | 521461 | 4747 | NM_006158 |  | --- | structural molecule activity /// structural constituent of cytoskeleton /// protein binding | intermediate filament /// neurofilament /// axon | --- | ---
U36310 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | GPD2 | 10_10 | 0.025134724 | decreased | 1.267818737767732 | 41021_s_at | 125853 /// 138430 | ENSG00000115159 | 148266 | 2820 | NM_000408 |  | glucose catabolism /// glycerol-3-phosphate metabolism /// electron transport | glycerol-3-phosphate dehydrogenase activity /// calcium ion binding /// oxidoreductase activity | mitochondrion /// glycerol-3-phosphate dehydrogenase complex | Fatty_Acid_Degradation | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Fatty_Acid_Degradation/Hs_Fatty_Acid_Degradation.htm
AI760162 | thioesterase superfamily member 2 | THEM2 | 8_10 | 0.018902335 | decreased | 1.601688575972096 | 41057_at | --- | ENSG00000112304 | 9676 | 55856 | NM_018473 |  | --- | hydrolase activity | --- | --- | ---
X63575 | ATPase, Ca++ transporting, plasma membrane 2 | ATP2B2 | 1_5 | 0.005537898 | increased | 2.477647487485067 | 41090_s_at | 108733 | ENSG00000157087 | 268942 | 491 | NM_001001331 /// NM_001683 |  | cation transport /// calcium ion transport /// metabolism | magnesium ion binding /// calcium-transporting ATPase activity /// calcium ion binding /// calmodulin binding /// ATP binding /// hydrolase activity /// hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | plasma membrane /// integral to membrane | Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
AL049970 | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) | PRKRIR | 6_10 | 0.033747073 | decreased | 0.7502210535610596 | 41141_at | 607374 | ENSG00000137492 | 503315 | 5612 | NM_004705 |  | regulation of translation /// response to stress /// signal transduction /// negative regulation of cell proliferation | DNA binding /// protein dimerization activity | --- | --- | ---
[NAME] | scavenger receptor class B, member 1 | SCARB1 | 5_6 | 0.027320881 | increased | 2.172850785122665 | 41200_at | 601040 | ENSG00000073060 | 298813 | 949 | NM_005505 |  | transport /// apoptosis /// cell adhesion /// cholesterol metabolism | receptor activity /// transporter activity | membrane fraction /// plasma membrane /// integral to membrane | Statin_Pathway_PharmGKB | [NAME]
AB007916 | solute carrier family 35, member [NAME] | SLC35E2 | 9_11 | 0.012559057 | decreased | 1.832469195966656 | 41243_at | --- | ENSG00000189339 /// ENSG00000169911 | 546331 | 9906 | NM_014854 /// NM_182838 |  | --- | catalytic activity | --- | --- | ---
AL040655 | serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | SERPINE2 | 5_2 | 0.030803495 | increased | 1.419677553099328 | 41246_at | 177010 | ENSG00000135919 | 38449 | 5270 | NM_006216 |  | neurogenesis /// cell differentiation /// regulation of proteolysis and peptidolysis /// regulation of cell migration | serine-type endopeptidase inhibitor activity /// heparin binding | extracellular region | --- | ---
AL031282 | NAD kinase | [NAME] | 4_11 | 0.02035785 | decreased | 2.023644485763892 | 41249_at | --- | ENSG00000008130 | 456572 | 65220 | NM_023018 |  | metabolism /// phosphorylation /// phosphorylation /// ATP metabolism /// ATP metabolism | NAD+ kinase activity /// NAD+ kinase activity /// transferase activity | cytosol /// cytosol | --- | ---
AF027156 | mannosidase, alpha, class 1A, member 2 | MAN1A2 | 1_1 | 0.019584924 | increased | 1.503922140528978 | 41298_at | 604345 | ENSG00000198162 | 435938 | 10905 | NM_006699 |  | carbohydrate metabolism /// N-glycan processing | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity /// calcium ion binding /// hydrolase activity, acting on glycosyl bonds | membrane fraction /// Golgi apparatus /// membrane /// integral to membrane | --- | ---
AA004795 | amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein | [NAME] | 7_5 | 0.029135849 | increased | 2.032141786287657 | 41306_at | --- | ENSG00000125967 | 516986 | 63941 | NM_031231 /// NM_031232 |  | protein secretion /// protein secretion /// antibiotic biosynthesis /// protein metabolism /// protein metabolism /// regulation of amyloid precursor protein biosynthesis | calcium ion binding /// protein binding /// protein binding /// protein binding /// oxidoreductase activity | Golgi [NAME] /// Golgi cis cisterna /// nucleus /// cytoplasm /// cytoplasm /// endoplasmic reticulum membrane /// endoplasmic reticulum membrane | --- | ---
U90917 | Clone 23641 mRNA sequence | --- | 6_10 | 0.029470243 | decreased | 1.733165525009806 | 41323_at | --- | --- | 535382 | --- | --- |  | --- | --- | --- | --- | ---
AI193606 | Potassium channel, subfamily K, member 3 | KCNK3 | 8_10 | 0.004958691 | decreased | 2.570526091113551 | 41326_at | 603220 | ENSG00000171303 | 24040 | 3777 | NM_002246 |  | ion transport /// potassium ion transport /// synaptic transmission | voltage-gated ion channel activity /// potassium channel activity | integral to plasma membrane /// membrane | --- | ---
AA885106 | Collagen, type VI, alpha 1 | COL6A1 | 7_3 | 0.007030535 | increased | 1.737210522392359 | 41351_at | 120220 /// 158810 /// 254090 /// 602475 | ENSG00000142156 | 474053 | 1291 | NM_001848 |  | phosphate transport /// cell adhesion | extracellular matrix structural constituent /// protein binding | [NAME] /// collagen type VI /// cytoplasm | --- | ---
W28148 | CCR4-NOT transcription complex, subunit 8 | CNOT8 | 8_10 | 0.02153542 | decreased | 2.276553357704872 | 41361_at | 603731 | ENSG00000155508 | 26703 | 9337 | NM_004779 |  | transcription /// regulation of transcription, DNA-dependent /// negative regulation of cell proliferation /// negative regulation of transcription | transcription factor activity /// transcriptional repressor activity | nucleus | --- | ---
AF070071 | mutS homolog 5 (E. coli) | [NAME] | 6_11 | 0.00862081 | decreased | 1.92214268167226 | 41467_at | 603382 | ENSG00000096474 | 371225 | 4439 | NM_002441 /// NM_025259 /// NM_172165 /// NM_172166 |  | DNA metabolism /// mismatch repair /// mismatch repair /// meiosis /// meiosis /// meiotic recombination /// meiotic prophase II | damaged DNA binding /// ATP binding | --- | Ovarian_Infertility_Genes | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Ovarian_Infertility_Genes/Hs_Ovarian_Infertility_Genes.htm
Y00971 | phosphoribosyl pyrophosphate synthetase 2 | PRPS2 | 3_10 | 1.02e-06 | decreased | 1.976940568026491 | 41490_at | 311860 | ENSG00000101911 | 104123 | 5634 | NM_002765 |  | nucleoside metabolism /// ribonucleoside monophosphate biosynthesis /// nucleotide biosynthesis | magnesium ion binding /// ribose-phosphate diphosphokinase activity /// kinase activity /// transferase activity /// lipoate-protein ligase B activity | --- | Nucleotide_Metabolism /// [NAME] phosphate pathway /// Purine metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Nucleotide_Metabolism/Hs_Nucleotide_Metabolism.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00030+2.7.6.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+2.7.6.1
AI094610 | Transcribed locus | --- | 7_3 | 0.02979105 | increased | 1.574244304880591 | 41493_at | --- | --- | 21363 | --- | --- |  | --- | --- | --- | --- | ---
AI971626 | Heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | HS3ST1 | 10_10 | 0.033537648 | decreased | 0.7886613405263022 | 41555_at | 603244 | ENSG00000002587 | 507348 | 9957 | NM_005114 |  | --- | heparin-glucosamine 3-O-sulfotransferase activity /// transferase activity | Golgi lumen /// integral to membrane | Chondroitin / Heparan sulfate biosynthesis | www.genome.ad.jp/dbget-bin/show_pathway?MAP00532+2.8.2.23
AI652660 | tetratricopeptide repeat domain 15 | TTC15 | 4_11 | 0.032594969 | decreased | 1.582871004999901 | 41590_at | --- | ENSG00000171853 | 252713 | 51112 | NM_016030 |  | --- | binding | --- | --- | ---
AF001436 | CDC42 effector protein (Rho GTPase binding) 2 | CDC42EP2 | 8_10 | 0.005641243 | decreased | 3.06663794916276 | 41658_at | 606132 | ENSG00000149798 | 343380 | 10435 | NM_006779 |  | actin cytoskeleton organization and biogenesis | Rho GTPase activator activity | plasma membrane | --- | ---
AF035282 | chromosome 1 open reading frame 21 | C1orf21 | 4_11 | 0.00104696 | decreased | 1.953749907543818 | 41679_at | --- | ENSG00000116667 | 132369 | 81563 | NM_030806 |  | --- | --- | --- | --- | ---
AB020662 | golgin-67 | GOLGIN-67 | 2_10 | 0.017135165 | decreased | 2.481733255007088 | 41767_r_at | --- | ENSG00000175265 | 182982 | 23015 | NM_015003 /// NM_181076 /// NM_181077 |  | --- | --- | Golgi apparatus | --- | ---
M97815 | cellular retinoic acid binding protein 2 | CRABP2 | 8_10 | 0.031699185 | decreased | 1.824008019751401 | 41783_at | 180231 | ENSG00000143320 | 405662 | 1382 | NM_001878 |  | regulation of transcription, DNA-dependent /// transport /// signal transduction /// epidermis development | transporter activity /// retinoid binding /// lipid binding | --- | --- | ---
AL080186 | chromosome 6 open reading frame 111 | C6orf111 | 10_10 | 0.006685064 | decreased | 1.956005115952271 | 41784_at | --- | ENSG00000132424 | 520287 | 25957 | NM_032870 |  | --- | --- | --- | --- | ---
AC002550 | esophageal cancer associated protein | MGC16824 | 6_11 | 0.008383419 | decreased | 2.49217015898305 | 41791_at | --- | ENSG00000103544 | 546412 | 57020 | NM_020314 |  | --- | --- | --- | --- | ---
AB018274 | likely ortholog of mouse la related protein | LARP | 4_11 | 0.012866357 | decreased | 1.688543457540271 | 41829_at | --- | ENSG00000155506 | 292078 | 23367 | NM_015315 /// NM_033551 |  | --- | --- | --- | --- | ---
AF055009 | cAMP responsive element binding protein 3-like 1 | CREB3L1 | 4_9 | 0.035403524 | decreased | 2.315352637301684 | 41867_at | --- | ENSG00000157613 | 405961 | 90993 | NM_052854 |  | regulation of transcription, DNA-dependent | transcription factor activity | nucleus | G1_to_S_cell_cycle_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G1_to_S_cell_cycle_Reactome/Hs_G1_to_S_cell_cycle_Reactome.htm
X13967 | leukemia inhibitory factor (cholinergic differentiation factor) | LIF | 7_3 | 0.019310568 | increased | 1.271069221856482 | 441_s_at | 159540 | ENSG00000128342 | 2250 | 3976 | NM_002309 |  | immune response /// cell surface receptor linked signal transduction /// cell-cell signaling /// development /// positive regulation of cell proliferation | cytokine activity /// leukemia inhibitory factor receptor binding /// oncostatin-M receptor binding /// growth factor activity | extracellular space | TGF_Beta_Signaling_Pathway | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_TGF_Beta_Signaling_Pathway/Hs_TGF_Beta_Signaling_Pathway.htm
U59302 | nuclear receptor coactivator 1 | NCOA1 | 4_11 | 0.021501183 | decreased | 1.964873803620244 | 484_at | 602691 | ENSG00000084676 | 412293 | 8648 | NM_003743 /// NM_147223 /// NM_147233 |  | transcription /// regulation of transcription, DNA-dependent /// signal transduction | transcription coactivator activity /// histone acetyltransferase activity /// signal transducer activity /// acyltransferase activity /// transferase activity | nucleus | --- | ---
U60521 | caspase 9, apoptosis-related cysteine protease | CASP9 | 10_10 | 0.034962608 | decreased | 3.1402344125064 | 486_at | 602234 | ENSG00000132906 | 329502 | 842 | NM_001229 /// NM_032996 |  | proteolysis and peptidolysis /// apoptotic program /// caspase activation via cytochrome c /// regulation of apoptosis | protein binding /// enzyme activator activity /// caspase activity | intracellular | Apoptosis /// Apoptosis_GenMAPP /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_GenMAPP/Hs_Apoptosis_GenMAPP.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
U07132 | nuclear receptor subfamily 1, group H, member 2 | NR1H2 | 9_11 | 0.014522165 | decreased | 1.896173140090706 | 518_at | 600380 | ENSG00000131408 | 432976 | 7376 | NM_007121 |  | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// steroid hormone receptor activity | nucleus | Nuclear_Receptors | [NAME]
U13695 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) | PMS1 | 6_10 | 6.66e-05 | decreased | 2.132962207909594 | 525_g_at | 114500 /// 600258 | ENSG00000064933 | 111749 | 5378 | NM_000534 |  | mismatch repair /// regulation of transcription, DNA-dependent /// cell cycle /// negative regulation of cell cycle | DNA binding /// ATP binding | nucleus /// nucleus /// inner membrane | --- | ---
M96738 | somatostatin receptor 3 | SSTR3 | 7_3 | 0.005279962 | increased | 2.207317261943313 | 557_s_at | 182453 | ENSG00000183473 | 225995 | 6753 | NM_001051 |  | signal transduction /// G-protein signaling, coupled to cyclic nucleotide second messenger /// cell-cell signaling /// negative regulation of cell proliferation /// induction of apoptosis by hormones | rhodopsin-like receptor activity /// receptor activity /// somatostatin receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
M31153 | cytochrome P450, family 17, subfamily A, polypeptide 1 | CYP17A1 | 5_1 | 0.03169035 | increased | 2.479945564546529 | 586_s_at | 202110 | ENSG00000148795 | 438016 | 1586 | NM_000102 |  | electron transport /// C21-steroid hormone biosynthesis /// transport /// sex differentiation | monooxygenase activity /// steroid 17-alpha-monooxygenase activity /// oxygen binding | endoplasmic reticulum /// microsome /// membrane | Glucocorticoid_Mineralocorticoid_Metabolism /// Steroid_Biosynthesis /// C21-Steroid hormone metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Glucocorticoid_Mineralocorticoid_Metabolism/Hs_Glucocorticoid_Mineralocorticoid_Metabolism.htm /// www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Steroid_Biosynthesis/Hs_Steroid_Biosynthesis.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00140+1.14.99.9
M32313 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | SRD5A1 | 10_7 | 0.031313297 | decreased | 1.420185518303079 | 589_at | 184753 | ENSG00000145545 | 552 | 6715 | NM_001047 |  | cell-cell signaling /// sex determination /// sex differentiation | 3-oxo-5-alpha-steroid 4-dehydrogenase activity /// electron transporter activity /// oxidoreductase activity | endoplasmic reticulum /// microsome /// integral to membrane | Bile acid biosynthesis /// Androgen and estrogen metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00120+1.3.99.5 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00150+1.3.99.5
M29037 | --- | --- | 7_3 | 0.034238123 | increased | 1.576119133962544 | 602_s_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
M22430 | phospholipase A2, group IIA (platelets, synovial fluid) | PLA2G2A | 1_3 | 0.00360183 | increased | 1.708677302659209 | 614_at | 172411 | ENSG00000188257 | 466804 | 5320 | NM_000300 |  | lipid catabolism | calcium ion binding /// hydrolase activity /// calcium-dependent phospholipase A2 activity | extracellular region /// membrane | Eicosanoid_Synthesis /// Glycerophospholipid metabolism /// Prostaglandin and leukotriene metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Eicosanoid_Synthesis/Hs_Eicosanoid_Synthesis.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00564+3.1.1.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00590+3.1.1.4
M28211 | RAB4A, member RAS oncogene family | RAB4A | 9_11 | 0.001574424 | decreased | 1.673555345456501 | 621_at | 179511 | ENSG00000168118 | 296169 | 5867 | [NAME] |  | intracellular protein transport /// small GTPase mediated signal transduction /// protein transport | GTPase activity /// GTP binding | --- | --- | ---
[NAME] | --- | --- | 7_3 | 0.032323866 | increased | 1.498131564598982 | 637_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
[NAME] | [NAME] 1 (Alzheimer disease 3) | PSEN1 | 9_11 | 0.013949111 | decreased | 1.687476098952297 | 641_at | 104311 /// 172700 /// 600274 /// 607822 | ENSG00000080815 | 3260 | 5663 | NM_000021 /// NM_007318 /// NM_007319 |  | membrane protein ectodomain proteolysis /// anti-apoptosis /// chromosome organization and biogenesis (sensu [NAME]) /// chromosome segregation /// Notch receptor processing /// intracellular signaling cascade /// protein processing /// amyloid precursor protein catabolism /// positive regulation of enzyme activity | protein binding | kinetochore /// membrane fraction /// integral to nuclear inner membrane /// mitochondrion /// endoplasmic reticulum /// Golgi apparatus /// integral to plasma membrane /// membrane /// integral to membrane | --- | ---
L37112 | arginine vasopressin receptor 1B | AVPR1B | 5_2 | 0.028243555 | increased | 1.037858165411752 | 648_at | 600264 | ENSG00000198049 | 1372 | 553 | NM_000707 |  | signal transduction /// G-protein coupled receptor protein signaling pathway /// phospholipase C activation /// positive regulation of cytosolic calcium ion concentration | rhodopsin-like receptor activity /// receptor activity /// vasopressin receptor activity /// protein kinase C binding | endosome /// plasma membrane /// integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
L20321 | NIMA (never in mitosis gene a)-related kinase 4 | [NAME] | 6_10 | 0.019264434 | decreased | 1.622829787965923 | 665_at | 601959 | ENSG00000114904 | 129550 | 6787 | NM_003157 |  | cytokinesis /// protein amino acid phosphorylation /// protein amino acid phosphorylation /// cell cycle /// mitosis | magnesium ion binding /// protein serine/threonine kinase activity /// protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity | nucleus | --- | ---
HG3527-HT3721 | --- | --- | 8_10 | 0.015186638 | decreased | 1.061373610974727 | 697_f_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
HG2167-HT2237 | --- | --- | 9_11 | 0.033167823 | decreased | 2.250931601782264 | 735_s_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
D21337 | collagen, type IV, alpha 6 | COL4A6 | 10_10 | 0.022768669 | decreased | 1.28545375946758 | 779_at | 303631 /// 308940 | ENSG00000197565 | 145586 | 1288 | NM_001847 /// NM_033641 |  | phosphate transport /// cell adhesion /// extracellular matrix organization and biogenesis | extracellular matrix structural constituent /// extracellular matrix structural constituent /// protein binding | [NAME] /// collagen type IV /// basement membrane /// cytoplasm | --- | ---
X62055 | protein tyrosine phosphatase, non-receptor type 6 | [NAME] | 7_3 | 0.017413843 | increased | 1.476245511297484 | 794_at | 176883 | ENSG00000111679 | 63489 | 5777 | NM_002831 /// NM_080548 /// NM_080549 |  | protein amino acid dephosphorylation /// protein amino acid dephosphorylation /// apoptosis /// G-protein coupled receptor protein signaling pathway /// intracellular signaling cascade /// negative regulation of cell proliferation | protein tyrosine phosphatase activity /// protein tyrosine phosphatase activity /// hydrolase activity | cytoskeleton /// membrane | --- | ---
U56998 | polo-like kinase 3 (Drosophila) | PLK3 | 1_5 | 0.008007984 | increased | 1.866026580345878 | 806_at | 602913 | ENSG00000173846 | 153640 | 1263 | NM_004073 |  | regulation of cell cycle /// protein amino acid phosphorylation | protein serine/threonine kinase activity /// protein binding /// ATP binding /// transferase activity | --- | Phosphatidylinositol signaling system | www.genome.ad.jp/dbget-bin/show_pathway?MAP04070+2.7.1.37
U48736 | PRP4 pre-mRNA processing factor 4 homolog B (yeast) | PRPF4B | 2_7 | 0.032932358 | decreased | 2.616716960208905 | 825_at | 602338 | ENSG00000112739 | 159014 | 8899 | NM_003913 /// NM_176800 |  | nuclear mRNA splicing, via spliceosome /// protein amino acid phosphorylation /// RNA splicing | protein serine/threonine kinase activity /// ATP binding /// transferase activity | nucleus | mRNA_processing_Reactome | [NAME]
U28042 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | DDX10 | 8_10 | 0.007084578 | decreased | 1.390204342160412 | 831_at | 601235 | ENSG00000178105 | 525115 | 1662 | NM_004398 |  | --- | RNA binding /// [NAME] helicase activity /// ATP binding /// ATP-dependent helicase activity /// hydrolase activity | --- | --- | ---
U19261 | TNF receptor-associated factor 1 | TRAF1 | 3_10 | 0.016598986 | decreased | 1.750200461326602 | 849_g_at | 601711 | ENSG00000056558 | 531251 | 7185 | [NAME] |  | protein complex assembly /// apoptosis | --- | cytoplasm | Apoptosis /// Apoptosis_GenMAPP /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_GenMAPP/Hs_Apoptosis_GenMAPP.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
L78440 | signal transducer and activator of transcription 4 | STAT4 | 7_3 | 0.007265631 | increased | 1.948510573120487 | 906_at | 600558 | ENSG00000138378 | 80642 | 6775 | NM_003151 |  | transcription /// regulation of transcription from RNA polymerase II promoter /// intracellular signaling cascade /// JAK-STAT cascade | transcription factor activity /// signal transducer activity /// calcium ion binding | nucleus | --- | ---
M13792 | adenosine deaminase | ADA | 1_1 | 0.00462548 | increased | 2.242997786680394 | 907_at | 608958 | ENSG00000196839 | 407135 | 100 | NM_000022 |  | nucleotide metabolism /// purine ribonucleoside monophosphate biosynthesis /// antimicrobial humoral response (sensu Vertebrata) | adenosine deaminase activity /// hydrolase activity | --- | Purine metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+3.5.4.4