Spreadsheet: 06c5926c-1da9-4427-901e-64a6e0747010
Sheet: S11

Table S11. Estimates of SLC24A5 nucleotide diversity measures among and within 8 geographic regions of the world.
 | Sub-Saharan Africa | North Afr/ Near East | Europe | Central Asia | South Asia | East Asia | Native American | Melanasia | Mean | [NAME]
No of gene copies | 44 | 14 | 22 | 14 | 46 | 28 | 8 | 12
No of polymorphic sites | 44 | 9 | 8 | 9 | 15 | 27 | 16 | 2
No of haplotypes | 28 | 3 | 8 | 8 | 11 | 18 | 3 | 3
Molecular Diversity indices
No of Transitions | 30 | 2 | 5 | 7 | 10 | 17 | 10 | 1 | 10.25 | 9.468
No of Transversions | 14 | 0 | 3 | 3 | 5 | 11 | 6 | 1 | 5.375 | 4.868
No of substitutions | 44 | 2 | 8 | 10 | 15 | 28 | 16 | 2 | 15.625 | 14.242
No of private substitutions | 21 | 0 | 5 | 1 | 1 | 4 | 0 | 1 | 4.125 | 7.06
No of indel sites | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.125 | 0.331
Pi (based on avearge pairwise differences) | 7.714 | 0.407 | 0.965 | 2.835 | 2.719 | 5.108 | 7 | 0.333 | 3.38519 | 2.91691
Theta_k | 32.10107 | 0.85483 | 4.06963 | 14.22808 | 5.01979 | 20.69796 | 1.25354 | 0.93396 | 9.89486 | 11.48285
Theta_k_lower | 17.79187 | 0.24125 | 1.7162 | 5.24708 | 2.42599 | 10.04044 | 0.33436 | 0.2606 | 4.75722 | 6.24399
Theta_k_upper | 58.64069 | 2.77486 | 9.3224 | 40.35913 | 10.04081 | 43.44002 | 4.46508 | 3.09012 | 21.51664 | 22.28327
Theta_H | 15.27416 | 0.46536 | 1.40208 | 12.6601 | 2.44808 | 11.04767 | 1.16329 | 0.34749 | 5.60103 | 6.25992
s.d Theta_H | 8.10462 | 0.29417 | 0.70701 | 11.34559 | 0.97295 | 6.49961 | 0.822 | 0.26184 | 3.62597 | 4.37114
Theta_S | 10.11495 | 0.6289 | 2.19457 | 3.14452 | 3.61726 | 7.19525 | 6.1708 | 0.66228 | 4.21607 | 3.35056
s.d Theta_S | 3.19673 | 0.47365 | 1.02688 | 1.47827 | 1.3863 | 2.57734 | 2.98895 | 0.5013 | 1.70368 | 1.08316
Theta_pi | 7.71353 | 0.40659 | 0.96537 | 2.83516 | 2.71905 | 5.10847 | 7 | 0.33333 | 3.38519 | 2.91691
s.d Theta_pi | 4.068 | 0.44652 | 0.76197 | 1.78352 | 1.64282 | 2.84267 | 4.19325 | 0.40132 | 2.01751 | 1.533942
Nucleotide diversity (average over the loci) ; s.d | 0.000657 +/- | 0.000035 +/- | 0.000082 +/- | 0.000249 +/- | 0.000194 +/- | 0.000435 +/- | 0.000596 +/- | 0.0000028 +/-
 | 0.000346 | 3.8e-05 | 6.5e-05 | 0.000156 | 0.000121 | 0.000242 | 0.000357 | 3.4e-05
Haplotype level computations
Sum of square freqs | 0.0775 | 0.6429 | 0.3802 | 0.1633 | 0.3686 | 0.1071 | 0.4688 | 0.7083
Gene diversity *; s.d | 0.9440 +/-  0.0260 | 0.3846 +/-  0.1494 | 0.6494 +/-  0.1107 | 0.9011 +/-  0.0523 | 0.6454 +/-  0.0775 | 0.9259 +/-  0.0370 | 0.6071 +/-  0.1640 | 0.3182 +/-  0.1637
s.d - Standard deviation
Theta_k is estimated from the infinite-allele equilibrium relationship (Ewens, 1972) between the expected number of alleles (k), the sample size (n) and θ
Theta_H The expected homozygosity in a population at equilibrium between drift and mutation
Theta_S is estimated from the infinite-site equilibrium relationship (Watterson, 1975) between the number of segregating sites (S), the sample size (n) and θ for a sample of non-recombining DNA
Theta_pi is estimated from the infinite-site equilibrium relationship between the mean number of pairwise differences (πˆ) and theta (θ ) (Tajima, 1983)
* - Equivalent to the expected heterozygosity for diploid data. It is defined as the probability that two randomly chosen haplotypes are different in the sample.