Spreadsheet: 88834517-1711-4e6c-b9bd-cb8ef2edb029
Sheet: reduced

Annotation Cluster 1 | Enrichment Score: 4.123446244751133
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | nucleotide-binding | 30 | 23.8095238095238 | 9.08952002556171e-07 | KIF25, [NAME], HRAS, [NAME], OAS2, PSKH2, PRKAR2A, ATP2B4, TOR1A, [NAME], PIK3CA, RHOB, ABCD4, PRKAA2, RAB6C, RAB2A, CSNK1A1, HSP90AA1, PIK3CB, ACACA, ATP1A3, ABCG8, TP53RK, ACVR2A, RAB31, GNAQ, LCK, TUBA4B, GNAS, ABCC2 | 126 | 1686 | 19235 | 2.71634751172117 | 0.000248113224294521 | 0.000248113224294521 | 0.00119714672592863
GOTERM_MF_FAT | GO:0017076~purine nucleotide binding | 33 | 26.1904761904761 | 0.000101329998848838 | KIF25, [NAME], HRAS, [NAME], OAS2, PSKH2, PRKAR2A, ATP2B4, TOR1A, [NAME], PIK3CA, RHOB, ABCD4, PRKAA2, RAB6C, CSNK1A1, RAB2A, IKBKAP, HSP90AA1, ACADM, PIK3CB, ACACA, ATP1A3, ABCG8, TP53RK, ACVR2A, RAB31, GNAQ, AOX1, LCK, TUBA4B, GNAS, ABCC2 | 112 | 1918 | 12983 | 1.99444640995084 | 0.0357255375175938 | 0.0357255375175938 | 0.13902024282214
GOTERM_MF_FAT | GO:0032555~purine ribonucleotide binding | 31 | 24.6031746031746 | 0.000261686833931408 | KIF25, [NAME], HRAS, [NAME], OAS2, PSKH2, PRKAR2A, ATP2B4, TOR1A, [NAME], PIK3CA, RHOB, ABCD4, PRKAA2, RAB6C, RAB2A, CSNK1A1, IKBKAP, HSP90AA1, PIK3CB, ACACA, ATP1A3, ABCG8, TP53RK, ACVR2A, RAB31, GNAQ, LCK, TUBA4B, GNAS, ABCC2 | 112 | 1836 | 12983 | 1.95724887177093 | 0.0896788846322186 | 0.0458925032430668 | 0.358656559923387
GOTERM_MF_FAT | GO:0032553~ribonucleotide binding | 31 | 24.6031746031746 | 0.000261686833931408 | KIF25, [NAME], HRAS, [NAME], OAS2, PSKH2, PRKAR2A, ATP2B4, TOR1A, [NAME], PIK3CA, RHOB, ABCD4, PRKAA2, RAB6C, RAB2A, CSNK1A1, IKBKAP, HSP90AA1, PIK3CB, ACACA, ATP1A3, ABCG8, TP53RK, ACVR2A, RAB31, GNAQ, LCK, TUBA4B, GNAS, ABCC2 | 112 | 1836 | 12983 | 1.95724887177093 | 0.0896788846322186 | 0.0458925032430668 | 0.358656559923387
GOTERM_MF_FAT | GO:0000166~nucleotide binding | 35 | 27.7777777777777 | 0.000382759555944772 | KIF25, [NAME], HRAS, [NAME], OAS2, PSKH2, TYMS, PRKAR2A, ATP2B4, TOR1A, [NAME], RHOB, PIK3CA, ABCD4, PRKAA2, SKIL, RAB6C, CSNK1A1, RAB2A, IKBKAP, HSP90AA1, ACADM, PIK3CB, ACACA, ATP1A3, ABCG8, TP53RK, ACVR2A, RAB31, GNAQ, AOX1, LCK, TUBA4B, GNAS, ABCC2 | 112 | 2245 | 12983 | 1.80721046770601 | 0.128410728467457 | 0.0447787866480458 | 0.524189680977549
Annotation Cluster 2 | Enrichment Score: 2.5881228144208923 | serine protease
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0008236~serine-type peptidase activity | 8 | 6.34920634920634 | 0.000829680429895173 | KLK8, GZMK, GZMA, TMPRSS11E, TOR1A, [NAME], KLK11, HGF | 112 | 178 | 12983 | 5.20987158908507 | 0.257683001289139 | 0.0717876308092095 | 1.13302397746204
GOTERM_MF_FAT | GO:0017171~serine hydrolase activity | 8 | 6.34920634920634 | 0.000885954593391587 | KLK8, GZMK, GZMA, TMPRSS11E, TOR1A, [NAME], KLK11, HGF | 112 | 180 | 12983 | 5.15198412698412 | 0.272541753447679 | 0.0616570091507684 | 1.20944012991927
INTERPRO | IPR001314:Peptidase S1A, chymotrypsin | 6 | 4.76190476190476 | 0.00100110057762788 | KLK8, GZMK, GZMA, TMPRSS11E, KLK11, HGF | 123 | 104 | 16659 | 7.81378986866791 | 0.306903705913956 | 0.306903705913956 | 1.36950636306472
INTERPRO | IPR001254:Peptidase S1 and S6, chymotrypsin/Hap | 6 | 4.76190476190476 | 0.00162876497573688 | KLK8, GZMK, GZMA, TMPRSS11E, KLK11, HGF | 123 | 116 | 16659 | 7.00546677880572 | 0.449326929887831 | 0.257926506259543 | 2.21925875501428
GOTERM_MF_FAT | GO:0004252~serine-type endopeptidase activity | 7 | 5.55555555555555 | 0.00205650575412516 | KLK8, GZMK, GZMA, TMPRSS11E, TOR1A, KLK11, HGF | 112 | 154 | 12983 | 5.26907467532467 | 0.522430582366958 | 0.0882420401642443 | 2.78659884645138
SMART | SM00020:Tryp_SPc | 6 | 4.76190476190476 | 0.00207794393509051 | KLK8, GZMK, GZMA, TMPRSS11E, KLK11, HGF | 72 | 116 | 9079 | 6.52227011494252 | 0.155059082625789 | 0.155059082625789 | 2.19244544675207
INTERPRO | IPR018114:Peptidase S1/S6, chymotrypsin/Hap, active site | 5 | 3.96825396825396 | 0.00741392269306752 | KLK8, GZMK, GZMA, TMPRSS11E, KLK11 | 123 | 105 | 16659 | 6.44947735191637 | 0.934362265301629 | 0.596616749353219 | 9.73790241200304
SP_PIR_KEYWORDS | [NAME] | 6 | 4.76190476190476 | 0.0111767961188652 | KLK8, GZMK, GZMA, TMPRSS11E, KLK11, MMP12 | 126 | 206 | 19235 | 4.44637078132223 | 0.953506611342159 | 0.184996613384313 | 13.7599111876284
SP_PIR_KEYWORDS | Serine protease | 5 | 3.96825396825396 | 0.0119979511448809 | KLK8, GZMK, GZMA, TMPRSS11E, KLK11 | 126 | 136 | 19235 | 5.61245331465919 | 0.962941166941652 | 0.186128700463552 | 14.6984042600261
Annotation Cluster 3 | Enrichment Score: 2.5628714080818678 | ATP binding
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | atp-binding | 21 | 16.6666666666666 | 0.000345175312901823 | CSNK1A1, KIF25, [NAME], [NAME], HSP90AA1, PIK3CB, ACACA, ATP1A3, OAS2, ABCG8, TP53RK, PSKH2, ACVR2A, ATP2B4, LCK, TOR1A, [NAME], PIK3CA, ABCD4, PRKAA2, ABCC2 | 126 | 1326 | 19235 | 2.41767219708396 | 0.0899439860680181 | 0.0186732785910257 | 0.45366631544782
GOTERM_MF_FAT | GO:0001883~purine nucleoside binding | 26 | 20.6349206349206 | 0.0018630871722933 | KIF25, [NAME], [NAME], OAS2, PSKH2, PRKAR2A, ATP2B4, TOR1A, [NAME], PIK3CA, RHOB, ABCD4, PRKAA2, CSNK1A1, IKBKAP, ACADM, HSP90AA1, PIK3CB, ACACA, ATP1A3, ABCG8, TP53RK, ACVR2A, LCK, AOX1, ABCC2 | 112 | 1601 | 12983 | 1.88251762291425 | 0.488021235891734 | 0.105578992036298 | 2.52761408596503
GOTERM_MF_FAT | GO:0001882~nucleoside binding | 26 | 20.6349206349206 | 0.00204886898602227 | KIF25, [NAME], [NAME], OAS2, PSKH2, PRKAR2A, ATP2B4, TOR1A, [NAME], PIK3CA, RHOB, ABCD4, PRKAA2, CSNK1A1, IKBKAP, ACADM, HSP90AA1, PIK3CB, ACACA, ATP1A3, ABCG8, TP53RK, ACVR2A, LCK, AOX1, ABCC2 | 112 | 1612 | 12983 | 1.86967165898617 | 0.521116781214592 | 0.0998424738483867 | 2.7763854310726
GOTERM_MF_FAT | [NAME]~adenyl nucleotide binding | 25 | 19.8412698412698 | 0.00328283285128796 | KIF25, [NAME], [NAME], OAS2, PSKH2, PRKAR2A, ATP2B4, TOR1A, [NAME], PIK3CA, ABCD4, PRKAA2, CSNK1A1, IKBKAP, ACADM, HSP90AA1, PIK3CB, ACACA, ATP1A3, ABCG8, TP53RK, ACVR2A, LCK, AOX1, ABCC2 | 112 | 1577 | 12983 | 1.83766079355014 | 0.692867401509689 | 0.111346222338713 | 4.41384453331598
GOTERM_MF_FAT | GO:0032559~adenyl ribonucleotide binding | 23 | 18.2539682539682 | 0.00750621603018001 | CSNK1A1, IKBKAP, KIF25, [NAME], [NAME], HSP90AA1, PIK3CB, ACACA, ATP1A3, OAS2, ABCG8, TP53RK, PSKH2, ACVR2A, PRKAR2A, ATP2B4, LCK, TOR1A, [NAME], PIK3CA, ABCD4, PRKAA2, ABCC2 | 112 | 1497 | 12983 | 1.78099651684321 | 0.933122725964471 | 0.20180951406588 | 9.82672283801046
GOTERM_MF_FAT | GO:0005524~ATP binding | 22 | 17.4603174603174 | 0.012921550524013 | CSNK1A1, IKBKAP, KIF25, [NAME], [NAME], HSP90AA1, PIK3CB, ACACA, ATP1A3, OAS2, ABCG8, TP53RK, PSKH2, ACVR2A, ATP2B4, LCK, TOR1A, [NAME], PIK3CA, ABCD4, PRKAA2, ABCC2 | 112 | 1477 | 12983 | 1.72662975142663 | 0.990618989795152 | 0.30173672560308 | 16.3516369896137
Annotation Cluster 4 | Enrichment Score: 2.456392329840087
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0042325~regulation of phosphorylation | 12 | 9.52380952380952 | 0.00285590782630369 | CCNE2, ACVR2A, [NAME], PRKAR2A, PIK3CB, GLMN, [NAME], IL6R, HGF, TLR6, BMP7, IRS1 | 121 | 466 | 13528 | 2.8790125208385 | 0.982869778886036 | 0.287452893682173 | 4.61156702888314
GOTERM_BP_FAT | GO:0051174~regulation of phosphorus metabolic process | 12 | 9.52380952380952 | 0.00386847159172471 | CCNE2, ACVR2A, [NAME], PRKAR2A, PIK3CB, GLMN, [NAME], IL6R, HGF, TLR6, BMP7, IRS1 | 121 | 485 | 13528 | 2.76622646332112 | 0.995960499731594 | 0.307496707237297 | 6.1980636949962
GOTERM_BP_FAT | GO:0019220~regulation of phosphate metabolic process | 12 | 9.52380952380952 | 0.00386847159172471 | CCNE2, ACVR2A, [NAME], PRKAR2A, PIK3CB, GLMN, [NAME], IL6R, HGF, TLR6, BMP7, IRS1 | 121 | 485 | 13528 | 2.76622646332112 | 0.995960499731594 | 0.307496707237297 | 6.1980636949962
Annotation Cluster 5 | Enrichment Score: 2.0640348125644947 | cation homeostasis
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0055080~cation homeostasis | 9 | 7.14285714285714 | 0.00394577380904451 | SRI, SLC9A8, [NAME], CCL13, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 286 | 13528 | 3.51823383228341 | 0.996382561910995 | 0.296279716160131 | 6.3181576132314
GOTERM_BP_FAT | GO:0030005~cellular di-, tri-valent inorganic cation homeostasis | 8 | 6.34920634920634 | 0.00409148455258533 | SRI, TRPC1, CCL13, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 227 | 13528 | 3.94014635744711 | 0.997061999155961 | 0.290321125587512 | 6.54413589923114
GOTERM_BP_FAT | GO:0055066~di-, tri-valent inorganic cation homeostasis | 8 | 6.34920634920634 | 0.00540670989950954 | SRI, TRPC1, CCL13, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 239 | 13528 | 3.74231474117362 | 0.999551320177463 | 0.333521515914615 | 8.56083417005386
GOTERM_BP_FAT | [NAME]~cellular calcium ion homeostasis | 7 | 5.55555555555555 | 0.00578083629472968 | TRPC1, CCL13, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 183 | 13528 | 4.27656595763898 | 0.999737222114883 | 0.324688369801819 | 9.1269874954625
GOTERM_BP_FAT | GO:0055074~calcium ion homeostasis | 7 | 5.55555555555555 | 0.006572995604818 | TRPC1, CCL13, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 188 | 13528 | 4.16282750131879 | 0.999915406511398 | 0.323440953300705 | 10.3148864639776
GOTERM_BP_FAT | GO:0030003~cellular cation homeostasis | 8 | 6.34920634920634 | 0.00747023324623207 | SRI, TRPC1, CCL13, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 254 | 13528 | 3.52131190212793 | 0.999976594682191 | 0.347211369623151 | 11.6427343156452
GOTERM_BP_FAT | [NAME]~cellular metal ion homeostasis | 7 | 5.55555555555555 | 0.00800061651116319 | TRPC1, CCL13, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 196 | 13528 | 3.99291617473435 | 0.999989055044608 | 0.355533216450274 | 12.4189549702498
GOTERM_BP_FAT | GO:0055065~metal ion homeostasis | 7 | 5.55555555555555 | 0.009859974956861 | TRPC1, CCL13, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 205 | 13528 | 3.81761741584358 | 0.999999240393215 | 0.384843210191934 | 15.0898482143177
GOTERM_BP_FAT | GO:0050801~ion homeostasis | 10 | 7.93650793650793 | 0.0105728222716788 | SRI, SLC9A8, [NAME], CCL13, GNAQ, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 409 | 13528 | 2.73353674553941 | 0.999999727219062 | 0.395781803030427 | 16.0933820312859
GOTERM_BP_FAT | GO:0006873~cellular ion homeostasis | 9 | 7.14285714285714 | 0.0182238992241293 | SRI, TRPC1, CCL13, GNAQ, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 374 | 13528 | 2.69041410704026 | 0.999999999995617 | 0.526328237792713 | 26.1855511653758
GOTERM_BP_FAT | GO:0055082~cellular chemical homeostasis | 9 | 7.14285714285714 | 0.0198427726061212 | SRI, TRPC1, CCL13, GNAQ, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 380 | 13528 | 2.64793388429752 | 0.99999999999958 | 0.537113654126483 | 28.1693291593786
GOTERM_BP_FAT | GO:0019725~cellular homeostasis | 10 | 7.93650793650793 | 0.0228094097156321 | SRI, [NAME], [NAME], CCL13, GNAQ, GRIK2, PIK3CB, LCK, AVPR1A, PKD2 | 121 | 466 | 13528 | 2.39917710069875 | 0.999999999999994 | 0.517669047682771 | 31.6753223656452
Annotation Cluster 6 | Enrichment Score: 1.874919785201569 | protease
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0004175~endopeptidase activity | 10 | 7.93650793650793 | 0.00482077708830517 | PIGK, KLK8, GZMK, GZMA, TMPRSS11E, PSMA3, TOR1A, KLK11, HGF, MMP12 | 112 | 375 | 12983 | 3.09119047619047 | 0.823572277495928 | 0.145905204898608 | 6.4188876301533
SP_PIR_KEYWORDS | Protease | 9 | 7.14285714285714 | 0.0137983778734932 | PIGK, KLK8, GZMK, GZMA, TMPRSS11E, PSMA3, [NAME], KLK11, MMP12 | 126 | 484 | 19235 | 2.83869539551357 | 0.977476311031217 | 0.172759142590611 | 16.723164359943
GOTERM_MF_FAT | GO:0070011~peptidase activity, acting on L-amino acid peptides | 11 | 8.73015873015873 | 0.0190293790689554 | PIGK, KLK8, GZMK, GZMA, TMPRSS11E, PSMA3, TOR1A, [NAME], KLK11, HGF, MMP12 | 112 | 549 | 12983 | 2.32261579495186 | 0.998989574442936 | 0.389007297735822 | 23.1842617892404
GOTERM_MF_FAT | GO:0008233~peptidase activity | 11 | 8.73015873015873 | 0.0250006417813508 | PIGK, KLK8, GZMK, GZMA, TMPRSS11E, PSMA3, TOR1A, [NAME], KLK11, HGF, MMP12 | 112 | 574 | 12983 | 2.22145657043305 | 0.999887136267454 | 0.454446984569768 | 29.3606008413366
Annotation Cluster 7 | Enrichment Score: 1.7954076407155928 | GTP binding
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0003924~GTPase activity | 8 | 6.34920634920634 | 0.00221023666026204 | RAB2A, RAB31, HRAS, GNAQ, RHOB, GNAS, TUBA4B, RAB6C | 112 | 211 | 12983 | 4.39505754908598 | 0.548126560283226 | 0.0844785267135623 | 2.99198714501938
SP_PIR_KEYWORDS | gtp-binding | 8 | 6.34920634920634 | 0.00574364402927052 | RAB2A, RAB31, HRAS, GNAQ, RHOB, GNAS, TUBA4B, RAB6C | 126 | 329 | 19235 | 3.71206638683842 | 0.792481585098726 | 0.106245314637539 | 7.30594904591939
GOTERM_MF_FAT | GO:0005525~GTP binding | 8 | 6.34920634920634 | 0.0403036238447544 | RAB2A, RAB31, HRAS, GNAQ, RHOB, GNAS, TUBA4B, RAB6C | 112 | 372 | 12983 | 2.4928955453149 | 0.99999961447379 | 0.58052213067111 | 43.1505404467763
GOTERM_MF_FAT | GO:0032561~guanyl ribonucleotide binding | 8 | 6.34920634920634 | 0.0453937124970623 | RAB2A, RAB31, HRAS, GNAQ, RHOB, GNAS, TUBA4B, RAB6C | 112 | 382 | 12983 | 2.42763649962602 | 0.999999942862623 | 0.604080690796434 | 47.1530768097182
GOTERM_MF_FAT | GO:0019001~guanyl nucleotide binding | 8 | 6.34920634920634 | 0.0453937124970623 | RAB2A, RAB31, HRAS, GNAQ, RHOB, GNAS, TUBA4B, RAB6C | 112 | 382 | 12983 | 2.42763649962602 | 0.999999942862623 | 0.604080690796434 | 47.1530768097182
Annotation Cluster 8 | Enrichment Score: 1.785358727560595 | protein complex assembly
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0070271~protein complex biogenesis | 11 | 8.73015873015873 | 0.0143106177246985 | IKBKAP, HRAS, HSP90AA1, PICALM, GRIK2, IPO5, TUBA4B, SKIL, PRKAA2, [NAME], IRS1 | 121 | 505 | 13528 | 2.43528352835283 | 0.999999998745728 | 0.483760372398001 | 21.1755361559221
GOTERM_BP_FAT | GO:0006461~protein complex assembly | 11 | 8.73015873015873 | 0.0143106177246985 | IKBKAP, HRAS, HSP90AA1, PICALM, GRIK2, IPO5, TUBA4B, SKIL, PRKAA2, [NAME], IRS1 | 121 | 505 | 13528 | 2.43528352835283 | 0.999999998745728 | 0.483760372398001 | 21.1755361559221
GOTERM_BP_FAT | GO:0065003~macromolecular complex assembly | 13 | 10.3174603174603 | 0.0149274212821762 | IKBKAP, HRAS, HSP90AA1, GRIK2, BIRC3, IRS1, PICALM, H2AFV, IPO5, H2AFZ, TUBA4B, PRKAA2, SKIL | 121 | 665 | 13528 | 2.18559622195985 | 0.999999999484981 | 0.487440290831627 | 21.9858571275547
GOTERM_BP_FAT | GO:0043933~macromolecular complex subunit organization | 13 | 10.3174603174603 | 0.023619110539592 | IKBKAP, HRAS, HSP90AA1, GRIK2, BIRC3, IRS1, PICALM, H2AFV, IPO5, H2AFZ, TUBA4B, PRKAA2, SKIL | 121 | 710 | 13528 | 2.04707251775113 | 0.999999999999998 | 0.522360696644659 | 32.603925266116
Annotation Cluster 9 | Enrichment Score: 1.6226435140766768 | regulation of osteoblast differentiation
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0045669~positive regulation of osteoblast differentiation | 4 | 3.17460317460317 | 0.00135766347539829 | ACVR2A, GNAS, IL6R, BMP7 | 121 | 25 | 13528 | 17.8882644628099 | 0.855128654125122 | 0.175675420954331 | 2.21779491996774
GOTERM_BP_FAT | GO:0045667~regulation of osteoblast differentiation | 4 | 3.17460317460317 | 0.00648835592235518 | ACVR2A, GNAS, IL6R, BMP7 | 121 | 43 | 13528 | 10.4001537574476 | 0.999904511472545 | 0.331324718208557 | 10.188662848218
GOTERM_BP_FAT | GO:0030278~regulation of ossification | 4 | 3.17460317460317 | 0.0320143233746015 | ACVR2A, GNAS, IL6R, BMP7 | 121 | 78 | 13528 | 5.73341809705446 | 1 | 0.596361532720804 | 41.5581591558666
GOTERM_BP_FAT | GO:0045597~positive regulation of cell differentiation | 5 | 3.96825396825396 | 0.146242078983065 | ACVR2A, GNAS, IL6R, BMP7, IL21 | 121 | 229 | 13528 | 2.44108412429174 | 1 | 0.848825317262982 | 92.6468755955066
GOTERM_BP_FAT | GO:0001934~positive regulation of protein amino acid phosphorylation | 3 | 2.38095238095238 | 0.186826703112496 | ACVR2A, IL6R, BMP7 | 121 | 89 | 13528 | 3.76859504132231 | 1 | 0.862902479888352 | 96.7092109216791
Annotation Cluster 10 | Enrichment Score: 1.6179130775820616 | [NAME]
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | prenylation | 6 | 4.76190476190476 | 0.00353597987644813 | RAB2A, RAB31, HRAS, RHOB, GNG2, RAB6C | 126 | 156 | 19235 | 5.87148962148962 | 0.619790636209734 | 0.0774245351704659 | 4.55822972738146
INTERPRO | [NAME]:[NAME] | 5 | 3.96825396825396 | 0.0134507599738009 | RAB2A, RAB31, HRAS, RHOB, RAB6C | 123 | 125 | 16659 | 5.41756097560975 | 0.992961688420592 | 0.62889765578872 | 17.0093372301091
INTERPRO | IPR001806:[NAME] | 5 | 3.96825396825396 | 0.0173772419096474 | RAB2A, RAB31, HRAS, RHOB, RAB6C | 123 | 135 | 16659 | 5.01626016260162 | 0.998364782445466 | 0.656761556838634 | 21.443092314431
INTERPRO | IPR005225:Small GTP-binding protein | 5 | 3.96825396825396 | 0.0344158073958142 | RAB2A, RAB31, HRAS, RHOB, RAB6C | 123 | 167 | 16659 | 4.05506061048634 | 0.999997288597784 | 0.839770678975922 | 38.2558138300342
GOTERM_BP_FAT | GO:0007264~small GTPase mediated signal transduction | 5 | 3.96825396825396 | 0.286048183974988 | RAB2A, RAB31, HRAS, RHOB, RAB6C | 121 | 305 | 13528 | 1.83281398184527 | 1 | 0.91539264041605 | 99.6159729417837
Annotation Cluster 11 | Enrichment Score: 1.4282971395560935 | regulation of kinase activity
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0033674~positive regulation of kinase activity | 7 | 5.55555555555555 | 0.0169352252756831 | [NAME], PRKAR2A, PIK3CB, TLR3, HGF, TLR6, IRS1 | 121 | 231 | 13528 | 3.38792887553218 | 0.999999999971699 | 0.510493241539807 | 24.5697311605137
GOTERM_BP_FAT | GO:0051347~positive regulation of transferase activity | 7 | 5.55555555555555 | 0.0200395648199354 | [NAME], PRKAR2A, PIK3CB, TLR3, HGF, TLR6, IRS1 | 121 | 240 | 13528 | 3.26088154269972 | 0.999999999999684 | 0.531171091151993 | 28.4070358211322
GOTERM_BP_FAT | GO:0043549~regulation of kinase activity | 8 | 6.34920634920634 | 0.0396784508184251 | CCNE2, [NAME], PRKAR2A, PIK3CB, TLR3, HGF, TLR6, IRS1 | 121 | 357 | 13528 | 2.50535916846077 | 1 | 0.655671933082901 | 48.7452724755431
GOTERM_BP_FAT | GO:0051338~regulation of transferase activity | 8 | 6.34920634920634 | 0.0476932177346614 | CCNE2, [NAME], PRKAR2A, PIK3CB, TLR3, HGF, TLR6, IRS1 | 121 | 372 | 13528 | 2.40433662134541 | 1 | 0.673985127272031 | 55.367825074852
GOTERM_BP_FAT | GO:0045860~positive regulation of protein kinase activity | 6 | 4.76190476190476 | 0.0484310817694527 | [NAME], PRKAR2A, PIK3CB, TLR3, HGF, TLR6 | 121 | 223 | 13528 | 3.00811622132453 | 1 | 0.673888888918731 | 55.9352853866994
GOTERM_BP_FAT | GO:0045859~regulation of protein kinase activity | 7 | 5.55555555555555 | 0.0865769729417225 | CCNE2, [NAME], PRKAR2A, PIK3CB, TLR3, HGF, TLR6 | 121 | 345 | 13528 | 2.26843933405198 | 1 | 0.749584320697165 | 77.5729857537152
Annotation Cluster 12 | Enrichment Score: 1.3308996792850445 | ion transport
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0030001~metal ion transport | 10 | 7.93650793650793 | 0.0225324959724231 | SRI, SLC9A8, [NAME], ATP2B4, LCK, ATP1A3, PKD2, CACNA1E, [NAME], KCNE3 | 121 | 465 | 13528 | 2.40433662134541 | 0.999999999999991 | 0.52936275405866 | 31.3549960489685
GOTERM_BP_FAT | GO:0006812~cation transport | 10 | 7.93650793650793 | 0.0573027357970435 | SRI, SLC9A8, [NAME], ATP2B4, LCK, ATP1A3, PKD2, CACNA1E, [NAME], KCNE3 | 121 | 553 | 13528 | 2.02172970872625 | 1 | 0.698428360090294 | 62.2483207078345
GOTERM_BP_FAT | GO:0006811~ion transport | 12 | 9.52380952380952 | 0.0787619215599366 | SRI, SLC9A8, [NAME], ATP2B4, GRIK2, LCK, ATP1A3, PKD2, CACNA1E, [NAME], RACGAP1, KCNE3 | 121 | 768 | 13528 | 1.74690082644628 | 1 | 0.746509012500465 | 74.1863194009106
Annotation Cluster 13 | Enrichment Score: 1.2195399593447642
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
BIOCARTA | h_metPathway:Signaling of Hepatocyte Growth Factor Receptor | 4 | 3.17460317460317 | 0.0346146350282715 | HRAS, PIK3CB, HGF, ITGB1 | 32 | 34 | 1437 | 5.28308823529411 | 0.991983267927861 | 0.799860663161826 | 33.9048444403743
BIOCARTA | h_ecmPathway:Erk and PI-3 [NAME] Collagen Binding in Corneal Epithelia | 3 | 2.38095238095238 | 0.0796269686226222 | HRAS, PIK3CB, ITGB1 | 32 | 22 | 1437 | 6.12357954545454 | 0.999988437488327 | 0.679147654506577 | 62.292689934522
BIOCARTA | h_tffPathway:Trefoil Factors Initiate  Mucosal Healing | 3 | 2.38095238095238 | 0.0796269686226222 | HRAS, PIK3CB, ITGB1 | 32 | 22 | 1437 | 6.12357954545454 | 0.999988437488327 | 0.679147654506577 | 62.292689934522
Annotation Cluster 14 | Enrichment Score: 1.1980952926028037
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0042108~positive regulation of cytokine biosynthetic process | 4 | 3.17460317460317 | 0.00880701982056448 | GLMN, [NAME], TLR6, IL21 | 121 | 48 | 13528 | 9.31680440771349 | 0.999996556615997 | 0.361894720643215 | 13.5868691391245
GOTERM_BP_FAT | GO:0042035~regulation of cytokine biosynthetic process | 4 | 3.17460317460317 | 0.0279774534229168 | GLMN, [NAME], TLR6, IL21 | 121 | 74 | 13528 | 6.04333258878713 | 1 | 0.561103295437679 | 37.4019755120919
GOTERM_BP_FAT | GO:0045089~positive regulation of innate immune response | 3 | 2.38095238095238 | 0.0627235962704684 | TLR3, TLR6, IL21 | 121 | 46 | 13528 | 7.29141214516708 | 1 | 0.711992812429274 | 65.6765549120253
GOTERM_BP_FAT | GO:0045088~regulation of innate immune response | 3 | 2.38095238095238 | 0.0828971880880726 | TLR3, TLR6, IL21 | 121 | 54 | 13528 | 6.21120293847566 | 1 | 0.749081351746732 | 76.0339962855058
GOTERM_BP_FAT | GO:0031349~positive regulation of defense response | 3 | 2.38095238095238 | 0.136922168347161 | TLR3, TLR6, IL21 | 121 | 73 | 13528 | 4.59458847503679 | 1 | 0.838101108389596 | 91.2034811381448
GOTERM_BP_FAT | GO:0050778~positive regulation of immune response | 3 | 2.38095238095238 | 0.369272163617468 | TLR3, TLR6, IL21 | 121 | 145 | 13528 | 2.313137646053 | 1 | 0.95188359668423 | 99.9503652697258
Annotation Cluster 15 | Enrichment Score: 1.1878540942539935
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | [NAME] | 11 | 8.73015873015873 | 0.0143205786985544 | PSKH2, TP53RK, CSNK1A1, ACVR2A, IKBKAP, PRKAR2A, PIK3CB, LCK, [NAME], PIK3CA, [NAME] | 126 | 688 | 19235 | 2.4407645810262 | 0.98050858996913 | 0.163885793534279 | 17.3020676190561
GOTERM_BP_FAT | GO:0006468~protein amino acid phosphorylation | 12 | 9.52380952380952 | 0.0346424458105835 | PSKH2, TP53RK, CSNK1A1, ACVR2A, IKBKAP, PIK3CB, LCK, [NAME], PIK3CA, HGF, PRKAA2, BMP7 | 121 | 667 | 13528 | 2.01142404004609 | 1 | 0.618687409590926 | 44.1230961954297
GOTERM_BP_FAT | GO:0016310~phosphorylation | 12 | 9.52380952380952 | 0.0979834529194971 | PSKH2, TP53RK, CSNK1A1, ACVR2A, IKBKAP, PIK3CB, LCK, [NAME], PIK3CA, HGF, PRKAA2, BMP7 | 121 | 800 | 13528 | 1.67702479338843 | 1 | 0.769245459823385 | 81.774490053191
GOTERM_BP_FAT | GO:0006796~phosphate metabolic process | 13 | 10.3174603174603 | 0.153816823051754 | CSNK1A1, IKBKAP, PIK3CB, ACP5, HGF, TP53RK, PSKH2, ACVR2A, LCK, [NAME], PIK3CA, PRKAA2, BMP7 | 121 | 973 | 13528 | 1.49375281356968 | 1 | 0.857260582996387 | 93.6528332604673
GOTERM_BP_FAT | GO:0006793~phosphorus metabolic process | 13 | 10.3174603174603 | 0.153816823051754 | CSNK1A1, IKBKAP, PIK3CB, ACP5, HGF, TP53RK, PSKH2, ACVR2A, LCK, [NAME], PIK3CA, PRKAA2, BMP7 | 121 | 973 | 13528 | 1.49375281356968 | 1 | 0.857260582996387 | 93.6528332604673
Annotation Cluster 16 | Enrichment Score: 1.1775631358814627 | SH3 domain
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | sh3 domain | 5 | 3.96825396825396 | 0.048278510652415 | TJP1, NEB, TP53BP2, LCK, BZRAP1 | 126 | 210 | 19235 | 3.63473167044595 | 0.999998641073318 | 0.362559185214811 | 47.8853250155317
INTERPRO | IPR001452:Src homology-3 domain | 5 | 3.96825396825396 | 0.0714407990165086 | TJP1, NEB, TP53BP2, LCK, BZRAP1 | 123 | 213 | 16659 | 3.17931982136722 | 0.999999999998346 | 0.93365147433881 | 63.9575915701103
SMART | SM00326:SH3 | 5 | 3.96825396825396 | 0.0850374884758674 | TJP1, NEB, TP53BP2, LCK, BZRAP1 | 72 | 213 | 9079 | 2.96002869066249 | 0.999252403399928 | 0.834645191219999 | 61.2151270376055
Annotation Cluster 17 | Enrichment Score: 1.1745013570865002 | sarcomere
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0030017~sarcomere | 4 | 3.17460317460317 | 0.0501161949362896 | SRI, TRPC1, DES, NEB | 109 | 98 | 12782 | 4.78636959370904 | 0.999981543792854 | 0.596808032560962 | 47.826044158324
GOTERM_CC_FAT | GO:0030018~Z disc | 3 | 2.38095238095238 | 0.0575589156278726 | SRI, DES, NEB | 109 | 46 | 12782 | 7.64778619864379 | 0.999996517488299 | 0.619683135921824 | 52.7691237426684
GOTERM_CC_FAT | GO:0030016~myofibril | 4 | 3.17460317460317 | 0.0676574473849729 | SRI, TRPC1, DES, NEB | 109 | 111 | 12782 | 4.22580378543681 | 0.999999645180651 | 0.628464354870486 | 58.7879627646408
GOTERM_CC_FAT | GO:0044449~contractile fiber part | 4 | 3.17460317460317 | 0.0705749638761939 | SRI, TRPC1, DES, NEB | 109 | 113 | 12782 | 4.15101079808394 | 0.999999817423111 | 0.620824417553794 | 60.3903569836635
GOTERM_CC_FAT | GO:0031674~I band | 3 | 2.38095238095238 | 0.078688783824364 | SRI, DES, NEB | 109 | 55 | 12782 | 6.39633027522935 | 0.999999971545695 | 0.640145986085535 | 64.5499915235147
GOTERM_CC_FAT | GO:0043292~contractile fiber | 4 | 3.17460317460317 | 0.0827984216323959 | SRI, TRPC1, DES, NEB | 109 | 121 | 12782 | 3.8765638031693 | 0.999999988970998 | 0.61877083664334 | 66.499693695075
Annotation Cluster 18 | Enrichment Score: 1.1556827907128642
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
INTERPRO | IPR003439:ABC transporter-like | 3 | 2.38095238095238 | 0.0482210532634716 | ABCG8, ABCD4, ABCC2 | 123 | 48 | 16659 | 8.46493902439024 | 0.99999998606168 | 0.895761944523858 | 49.3601451908698
INTERPRO | IPR017871:ABC transporter, conserved site | 3 | 2.38095238095238 | 0.0654162073161284 | ABCG8, ABCD4, ABCC2 | 123 | 57 | 16659 | 7.12836970474967 | 0.999999999982369 | 0.936152782281146 | 60.6012646910911
KEGG_PATHWAY | hsa02010:ABC transporters | 3 | 2.38095238095238 | 0.1081507597273 | ABCG8, ABCD4, ABCC2 | 66 | 44 | 5085 | 5.25309917355372 | 0.999994618623849 | 0.490350206287838 | 72.3166047522107
Annotation Cluster 19 | Enrichment Score: 1.110530818811037
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0042327~positive regulation of phosphorylation | 4 | 3.17460317460317 | 0.0550614778300335 | ACVR2A, GLMN, IL6R, BMP7 | 121 | 97 | 13528 | 4.61037743886853 | 1 | 0.704839393285132 | 60.7390205812263
GOTERM_BP_FAT | GO:0045937~positive regulation of phosphate metabolic process | 4 | 3.17460317460317 | 0.059264545156986 | ACVR2A, GLMN, IL6R, BMP7 | 121 | 100 | 13528 | 4.47206611570247 | 1 | 0.700784996738939 | 63.5245305291794
GOTERM_BP_FAT | GO:0010562~positive regulation of phosphorus metabolic process | 4 | 3.17460317460317 | 0.059264545156986 | ACVR2A, GLMN, IL6R, BMP7 | 121 | 100 | 13528 | 4.47206611570247 | 1 | 0.700784996738939 | 63.5245305291794
GOTERM_BP_FAT | GO:0001934~positive regulation of protein amino acid phosphorylation | 3 | 2.38095238095238 | 0.186826703112496 | ACVR2A, IL6R, BMP7 | 121 | 89 | 13528 | 3.76859504132231 | 1 | 0.862902479888352 | 96.7092109216791
Annotation Cluster 20 | Enrichment Score: 1.1021509961793443
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0019217~regulation of fatty acid metabolic process | 3 | 2.38095238095238 | 0.0700709082303105 | AVPR1A, PRKAA2, IRS1 | 121 | 49 | 13528 | 6.84499915668746 | 1 | 0.729543752545312 | 69.8582188398284
GOTERM_BP_FAT | GO:0019216~regulation of lipid metabolic process | 4 | 3.17460317460317 | 0.0775161585780609 | NPC2, AVPR1A, PRKAA2, IRS1 | 121 | 112 | 13528 | 3.99291617473435 | 1 | 0.74484622689081 | 73.6039903864183
GOTERM_BP_FAT | GO:0010565~regulation of cellular ketone metabolic process | 3 | 2.38095238095238 | 0.0909111229505155 | AVPR1A, PRKAA2, IRS1 | 121 | 57 | 13528 | 5.88429752066115 | 1 | 0.752726521049984 | 79.2665163707289
Annotation Cluster 21 | Enrichment Score: 1.0844012595325723
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | [NAME]~negative regulation of neurological system process | 3 | 2.38095238095238 | 0.0253796893446274 | KLK8, GRIK2, AVPR1A | 121 | 28 | 13528 | 11.978748524203 | 0.999999999999999 | 0.533071446397736 | 34.5822808993927
GOTERM_BP_FAT | GO:0051969~regulation of transmission of nerve impulse | 4 | 3.17460317460317 | 0.142187270484975 | HRAS, KLK8, GRIK2, AVPR1A | 121 | 147 | 13528 | 3.04222184741665 | 1 | 0.844953298909853 | 92.0486447282478
GOTERM_BP_FAT | GO:0031644~regulation of neurological system process | 4 | 3.17460317460317 | 0.154685356369879 | HRAS, KLK8, GRIK2, AVPR1A | 121 | 153 | 13528 | 2.9229190298709 | 1 | 0.856694976345479 | 93.759528291178
Annotation Cluster 22 | Enrichment Score: 1.0815320102326658
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
BIOCARTA | h_igf1Pathway:IGF-1 [NAME] | 3 | 2.38095238095238 | 0.0613358005823451 | HRAS, PIK3CB, IRS1 | 32 | 19 | 1437 | 7.09046052631578 | 0.999828641824873 | 0.710274711448129 | 52.4795010890722
BIOCARTA | h_insulinPathway:[NAME] | 3 | 2.38095238095238 | 0.0613358005823451 | HRAS, PIK3CB, IRS1 | 32 | 19 | 1437 | 7.09046052631578 | 0.999828641824873 | 0.710274711448129 | 52.4795010890722
BIOCARTA | h_ghPathway:Growth Hormone Signaling Pathway | 3 | 2.38095238095238 | 0.0796269686226222 | HRAS, PIK3CB, IRS1 | 32 | 22 | 1437 | 6.12357954545454 | 0.999988437488327 | 0.679147654506577 | 62.292689934522
BIOCARTA | h_il2rbPathway:IL-2 Receptor Beta Chain in T cell Activation | 3 | 2.38095238095238 | 0.157537409579334 | HRAS, PIK3CB, IRS1 | 32 | 33 | 1437 | 4.08238636363636 | 0.999999999936841 | 0.835782995381992 | 86.6675562081526
Annotation Cluster 23 | Enrichment Score: 1.0599565622932874 | inflammatory response
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
INTERPRO | IPR000157:Toll-Interleukin receptor | 3 | 2.38095238095238 | 0.0121712115590539 | [NAME], [NAME], TLR6 | 123 | 23 | 16659 | 17.6659597030752 | 0.988689171669235 | 0.673882876691164 | 15.5150768657547
SMART | SM00255:TIR | 3 | 2.38095238095238 | 0.0137205784873438 | [NAME], [NAME], TLR6 | 72 | 23 | 9079 | 16.4474637681159 | 0.673413887586745 | 0.42852286798748 | 13.6910683547211
SP_PIR_KEYWORDS | inflammatory response | 4 | 3.17460317460317 | 0.0138224167159935 | CCL13, [NAME], [NAME], TLR6 | 126 | 77 | 19235 | 7.93032364460935 | 0.977625697442713 | 0.165518634274142 | 16.7498954376869
GOTERM_BP_FAT | GO:0010740~positive regulation of protein kinase cascade | 4 | 3.17460317460317 | 0.185086652649031 | [NAME], TLR3, IL6R, TLR6 | 121 | 167 | 13528 | 2.67788390161825 | 1 | 0.861917338314357 | 96.591017117561
GOTERM_BP_FAT | GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB cascade | 3 | 2.38095238095238 | 0.21265094765624 | [NAME], [NAME], TLR6 | 121 | 97 | 13528 | 3.4577830791514 | 1 | 0.87419595803446 | 98.0683572732197
GOTERM_BP_FAT | GO:0043122~regulation of I-kappaB kinase/NF-kappaB cascade | 3 | 2.38095238095238 | 0.245364307433276 | [NAME], [NAME], TLR6 | 121 | 107 | 13528 | 3.13462578203444 | 1 | 0.891825472785921 | 99.0412964006185
GOTERM_BP_FAT | GO:0045087~innate immune response | 3 | 2.38095238095238 | 0.346830933557226 | [NAME], [NAME], TLR6 | 121 | 138 | 13528 | 2.43047071505569 | 1 | 0.945622972970557 | 99.9116030739732
SP_PIR_KEYWORDS | immune response | 3 | 2.38095238095238 | 0.42863304579706 | [NAME], [NAME], TLR6 | 126 | 224 | 19235 | 2.04453656462585 | 1 | 0.901255586039581 | 99.937135982578
Annotation Cluster 24 | Enrichment Score: 1.045903653830232
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0080135~regulation of cellular response to stress | 4 | 3.17460317460317 | 0.0636145297310274 | KLK8, GRIK2, TLR3, TLR6 | 121 | 103 | 13528 | 4.34181176281794 | 1 | 0.71240556955686 | 66.2112000394077
GOTERM_BP_FAT | GO:0043408~regulation of MAPKKK cascade | 4 | 3.17460317460317 | 0.0727434607989771 | GRIK2, TLR3, IL6R, TLR6 | 121 | 109 | 13528 | 4.10281295018576 | 1 | 0.738796912078506 | 71.2568052797027
GOTERM_BP_FAT | GO:0046328~regulation of JNK cascade | 3 | 2.38095238095238 | 0.113297345485955 | GRIK2, TLR3, TLR6 | 121 | 65 | 13528 | 5.16007628734901 | 1 | 0.794689837514332 | 86.2621810309855
GOTERM_BP_FAT | GO:0070302~regulation of stress-activated protein kinase signaling pathway | 3 | 2.38095238095238 | 0.124972762547809 | GRIK2, TLR3, TLR6 | 121 | 69 | 13528 | 4.86094143011139 | 1 | 0.813621696488267 | 88.9620008650442
Annotation Cluster 25 | Enrichment Score: 1.0097727729099555
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
BIOCARTA | h_crebPathway:Transcription factor CREB and its extracellular signals | 4 | 3.17460317460317 | 0.00596093200087307 | HRAS, [NAME], PIK3CA, GNAS | 32 | 18 | 1437 | 9.97916666666666 | 0.559167983379907 | 0.559167983379907 | 6.78629639577171
BIOCARTA | h_gpcrPathway:Signaling Pathway from G-Protein Families | 4 | 3.17460317460317 | 0.00929827368866366 | HRAS, [NAME], GNAQ, GNAS | 32 | 21 | 1437 | 8.55357142857142 | 0.721913435549664 | 0.472660863911717 | 10.3990922987737
KEGG_PATHWAY | hsa04540:Gap junction | 5 | 3.96825396825396 | 0.0264055879714671 | HRAS, [NAME], TJP1, GNAQ, GNAS | 66 | 89 | 5085 | 4.32839632277834 | 0.941375966755854 | 0.333176627880626 | 25.9389055391777
GOTERM_BP_FAT | GO:0010579~positive regulation of adenylate cyclase activity by G-protein signaling pathway | 3 | 2.38095238095238 | 0.0489051728218022 | [NAME], GNAQ, GNAS | 121 | 40 | 13528 | 8.38512396694214 | 1 | 0.671783437598449 | 56.2963049688818
GOTERM_BP_FAT | GO:0010578~regulation of adenylate cyclase activity involved in G-protein signaling | 3 | 2.38095238095238 | 0.0489051728218022 | [NAME], GNAQ, GNAS | 121 | 40 | 13528 | 8.38512396694214 | 1 | 0.671783437598449 | 56.2963049688818
GOTERM_BP_FAT | GO:0007189~activation of adenylate cyclase activity by G-protein signaling pathway | 3 | 2.38095238095238 | 0.0489051728218022 | [NAME], GNAQ, GNAS | 121 | 40 | 13528 | 8.38512396694214 | 1 | 0.671783437598449 | 56.2963049688818
BIOCARTA | h_bArrestin-srcPathway:Roles of ???-arrestin-dependent [NAME] in GPCR Signaling | 3 | 2.38095238095238 | 0.0556136828015948 | HRAS, [NAME], GNAS | 32 | 18 | 1437 | 7.484375 | 0.999605990219545 | 0.729240003133357 | 48.9606294171156
GOTERM_BP_FAT | GO:0030814~regulation of cAMP metabolic process | 4 | 3.17460317460317 | 0.0636145297310274 | [NAME], GNAQ, PKD2, GNAS | 121 | 103 | 13528 | 4.34181176281794 | 1 | 0.71240556955686 | 66.2112000394077
BIOCARTA | h_mPRPathway:How Progesterone Initiates the Oocyte Maturation | 3 | 2.38095238095238 | 0.0672522874319917 | HRAS, [NAME], GNAS | 32 | 20 | 1437 | 6.73593749999999 | 0.99992793997714 | 0.69646288679626 | 55.8832683213962
BIOCARTA | h_CCR3Pathway:CCR3 signaling in Eosinophils | 3 | 2.38095238095238 | 0.073352709931363 | HRAS, GNAQ, GNAS | 32 | 21 | 1437 | 6.41517857142857 | 0.999970672096344 | 0.68640830113958 | 59.1579904137367
GOTERM_BP_FAT | GO:0030799~regulation of cyclic nucleotide metabolic process | 4 | 3.17460317460317 | 0.0791371018439972 | [NAME], GNAQ, PKD2, GNAS | 121 | 113 | 13528 | 3.95758063336502 | 1 | 0.744160214245488 | 74.3593179268095
GOTERM_BP_FAT | GO:0006140~regulation of nucleotide metabolic process | 4 | 3.17460317460317 | 0.0840883098922154 | [NAME], GNAQ, PKD2, GNAS | 121 | 116 | 13528 | 3.85522941008834 | 1 | 0.750375669364657 | 76.5426951654615
GOTERM_BP_FAT | GO:0007190~activation of adenylate cyclase activity | 3 | 2.38095238095238 | 0.0855433185032458 | [NAME], GNAQ, GNAS | 121 | 55 | 13528 | 6.09827197595792 | 1 | 0.752758895414961 | 77.1503316928684
GOTERM_BP_FAT | GO:0045762~positive regulation of adenylate cyclase activity | 3 | 2.38095238095238 | 0.0882148466637856 | [NAME], GNAQ, GNAS | 121 | 56 | 13528 | 5.98937426210153 | 1 | 0.749011226543565 | 78.2276930978214
GOTERM_BP_FAT | GO:0031281~positive regulation of cyclase activity | 3 | 2.38095238095238 | 0.0909111229505155 | [NAME], GNAQ, GNAS | 121 | 57 | 13528 | 5.88429752066115 | 1 | 0.752726521049984 | 79.2665163707289
GOTERM_BP_FAT | GO:0051349~positive regulation of lyase activity | 3 | 2.38095238095238 | 0.0963753680395361 | [NAME], GNAQ, GNAS | 121 | 59 | 13528 | 5.68482980809637 | 1 | 0.770185312438399 | 81.2306350073314
KEGG_PATHWAY | hsa04912:[NAME] signaling pathway | 4 | 3.17460317460317 | 0.129378520537148 | HRAS, [NAME], GNAQ, GNAS | 66 | 98 | 5085 | 3.14471243042671 | 0.999999581289331 | 0.503085556459186 | 78.8736596521452
KEGG_PATHWAY | hsa04916:Melanogenesis | 4 | 3.17460317460317 | 0.132263482627368 | HRAS, [NAME], GNAQ, GNAS | 66 | 99 | 5085 | 3.1129476584022 | 0.999999705480067 | 0.495174159589766 | 79.6460296733246
GOTERM_BP_FAT | GO:0007188~G-protein signaling, coupled to cAMP nucleotide second messenger | 3 | 2.38095238095238 | 0.174093150694871 | [NAME], GNAQ, GNAS | 121 | 85 | 13528 | 3.94594069032571 | 1 | 0.860675071551515 | 95.7469982823068
GOTERM_BP_FAT | GO:0019933~cAMP-mediated signaling | 3 | 2.38095238095238 | 0.20615776155383 | [NAME], GNAQ, GNAS | 121 | 95 | 13528 | 3.53057851239669 | 1 | 0.871504556177605 | 97.7878773905838
GOTERM_BP_FAT | GO:0045761~regulation of adenylate cyclase activity | 3 | 2.38095238095238 | 0.209401680234562 | [NAME], GNAQ, GNAS | 121 | 96 | 13528 | 3.49380165289256 | 1 | 0.871241866998754 | 97.9324658039671
KEGG_PATHWAY | hsa04720:Long-term potentiation | 3 | 2.38095238095238 | 0.215602626761369 | HRAS, [NAME], GNAQ | 66 | 68 | 5085 | 3.39906417112299 | 0.99999999999338 | 0.576004746367882 | 93.4447710585363
GOTERM_BP_FAT | GO:0031279~regulation of cyclase activity | 3 | 2.38095238095238 | 0.219164148423897 | [NAME], GNAQ, GNAS | 121 | 99 | 13528 | 3.38792887553218 | 1 | 0.878339541335361 | 98.3158799988744
KEGG_PATHWAY | [NAME]:Long-term depression | 3 | 2.38095238095238 | 0.220321253842074 | HRAS, GNAQ, GNAS | 66 | 69 | 5085 | 3.3498023715415 | 0.999999999996508 | 0.573006355553633 | 93.8739024017578
GOTERM_BP_FAT | GO:0030817~regulation of cAMP biosynthetic process | 3 | 2.38095238095238 | 0.225694659157466 | [NAME], GNAQ, GNAS | 121 | 101 | 13528 | 3.32084117502659 | 1 | 0.885258219225727 | 98.5339116301733
GOTERM_BP_FAT | GO:0051339~regulation of lyase activity | 3 | 2.38095238095238 | 0.225694659157466 | [NAME], GNAQ, GNAS | 121 | 101 | 13528 | 3.32084117502659 | 1 | 0.885258219225727 | 98.5339116301733
GOTERM_BP_FAT | GO:0030808~regulation of nucleotide biosynthetic process | 3 | 2.38095238095238 | 0.255227983930515 | [NAME], GNAQ, GNAS | 121 | 110 | 13528 | 3.04913598797896 | 1 | 0.898711884377445 | 99.2284615040799
GOTERM_BP_FAT | GO:0030802~regulation of cyclic nucleotide biosynthetic process | 3 | 2.38095238095238 | 0.255227983930515 | [NAME], GNAQ, GNAS | 121 | 110 | 13528 | 3.04913598797896 | 1 | 0.898711884377445 | 99.2284615040799
GOTERM_BP_FAT | GO:0007187~G-protein signaling, coupled to cyclic nucleotide second messenger | 3 | 2.38095238095238 | 0.271683603876331 | [NAME], GNAQ, GNAS | 121 | 115 | 13528 | 2.91656485806683 | 1 | 0.909089808332068 | 99.4664491212578
GOTERM_BP_FAT | GO:0019935~cyclic-nucleotide-mediated signaling | 3 | 2.38095238095238 | 0.320882527192007 | [NAME], GNAQ, GNAS | 121 | 130 | 13528 | 2.5800381436745 | 1 | 0.935274873775701 | 99.8318327557073
Annotation Cluster 26 | Enrichment Score: 1.0071738140687116 | Protein transport
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0015031~protein transport | 12 | 9.52380952380952 | 0.0754478530632296 | RAB2A, RAB31, STX2, GRIK2, IPO5, RHOB, GNAS, [NAME], [NAME], RAMP1, RAB6C, HDAC6 | 121 | 762 | 13528 | 1.76065595106396 | 1 | 0.743432987250763 | 72.6098310557523
GOTERM_BP_FAT | GO:0045184~establishment of protein localization | 12 | 9.52380952380952 | 0.0793231297797332 | RAB2A, RAB31, STX2, GRIK2, IPO5, RHOB, GNAS, [NAME], [NAME], RAMP1, RAB6C, HDAC6 | 121 | 769 | 13528 | 1.74462917387613 | 1 | 0.740976655466822 | 74.4446923655526
GOTERM_BP_FAT | GO:0008104~protein localization | 12 | 9.52380952380952 | 0.159012706756562 | RAB2A, RAB31, STX2, GRIK2, IPO5, RHOB, GNAS, [NAME], [NAME], RAMP1, RAB6C, HDAC6 | 121 | 882 | 13528 | 1.52111092370832 | 1 | 0.856160374425862 | 94.2664750807361
Annotation Cluster 27 | Enrichment Score: 0.9799294273190626 | regulation of apoptosis
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0042981~regulation of apoptosis | 12 | 9.52380952380952 | 0.100569845365163 | BAG4, HRAS, GRIK2, TP53BP2, LCK, CD2, PIK3CA, IL6R, HGF, [NAME], BMP7, HDAC6 | 121 | 804 | 13528 | 1.66868138645614 | 1 | 0.775147319050126 | 82.6182630921535
GOTERM_BP_FAT | GO:0043067~regulation of programmed cell death | 12 | 9.52380952380952 | 0.105864961943745 | BAG4, HRAS, GRIK2, TP53BP2, LCK, CD2, PIK3CA, IL6R, HGF, [NAME], BMP7, HDAC6 | 121 | 812 | 13528 | 1.65224117575214 | 1 | 0.786656271605337 | 84.232561940135
GOTERM_BP_FAT | GO:0010941~regulation of cell death | 12 | 9.52380952380952 | 0.107892607720962 | BAG4, HRAS, GRIK2, TP53BP2, LCK, CD2, PIK3CA, IL6R, HGF, [NAME], BMP7, HDAC6 | 121 | 815 | 13528 | 1.64615930639355 | 1 | 0.790081983089812 | 84.8125584975289
Annotation Cluster 28 | Enrichment Score: 0.9659182493534688
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0030335~positive regulation of cell migration | 4 | 3.17460317460317 | 0.044591882510794 | IL6R, CBLL1, IRS1, HDAC6 | 121 | 89 | 13528 | 5.02479338842975 | 1 | 0.673196169393994 | 52.9067994754838
GOTERM_BP_FAT | GO:0040017~positive regulation of locomotion | 4 | 3.17460317460317 | 0.0564460029912402 | IL6R, CBLL1, IRS1, HDAC6 | 121 | 98 | 13528 | 4.56333277112497 | 1 | 0.703292588295998 | 61.6779361146874
GOTERM_BP_FAT | GO:0051272~positive regulation of cell motion | 4 | 3.17460317460317 | 0.0564460029912402 | IL6R, CBLL1, IRS1, HDAC6 | 121 | 98 | 13528 | 4.56333277112497 | 1 | 0.703292588295998 | 61.6779361146874
GOTERM_BP_FAT | GO:0030334~regulation of cell migration | 4 | 3.17460317460317 | 0.189554611647158 | IL6R, CBLL1, IRS1, HDAC6 | 121 | 169 | 13528 | 2.64619296787128 | 1 | 0.861824305420809 | 96.8867858408564
GOTERM_BP_FAT | GO:0040012~regulation of locomotion | 4 | 3.17460317460317 | 0.242665822041353 | IL6R, CBLL1, IRS1, HDAC6 | 121 | 192 | 13528 | 2.32920110192837 | 1 | 0.892796613148097 | 98.9831068069218
GOTERM_BP_FAT | GO:0051270~regulation of cell motion | 4 | 3.17460317460317 | 0.245033430432831 | IL6R, CBLL1, IRS1, HDAC6 | 121 | 193 | 13528 | 2.31713270243651 | 1 | 0.892788480819646 | 99.0343335673852
Annotation Cluster 29 | Enrichment Score: 0.9291933517553591
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0042626~ATPase activity, coupled to transmembrane movement of substances | 4 | 3.17460317460317 | 0.0666525960746349 | ATP2B4, ATP1A3, ABCD4, ABCC2 | 112 | 109 | 12983 | 4.25393184796854 | 0.999999999982398 | 0.710080342530706 | 61.2079577385406
GOTERM_MF_FAT | GO:0043492~ATPase activity, coupled to movement of substances | 4 | 3.17460317460317 | 0.0681116455798693 | ATP2B4, ATP1A3, ABCD4, ABCC2 | 112 | 110 | 12983 | 4.21525974025974 | 0.999999999989962 | 0.700588614346577 | 62.0322355626374
GOTERM_MF_FAT | GO:0016820~hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 4 | 3.17460317460317 | 0.0695852469169132 | ATP2B4, ATP1A3, ABCD4, ABCC2 | 112 | 111 | 12983 | 4.17728442728442 | 0.999999999994312 | 0.691781380995425 | 62.8482270090101
GOTERM_MF_FAT | GO:0015399~primary active transmembrane transporter activity | 4 | 3.17460317460317 | 0.0867245913110419 | ATP2B4, ATP1A3, ABCD4, ABCC2 | 112 | 122 | 12983 | 3.80064402810304 | 0.999999999999992 | 0.728205084669014 | 71.2177267194641
GOTERM_MF_FAT | GO:0015405~P-P-bond-hydrolysis-driven transmembrane transporter activity | 4 | 3.17460317460317 | 0.0867245913110419 | ATP2B4, ATP1A3, ABCD4, ABCC2 | 112 | 122 | 12983 | 3.80064402810304 | 0.999999999999992 | 0.728205084669014 | 71.2177267194641
GOTERM_MF_FAT | GO:0016887~ATPase activity | 5 | 3.96825396825396 | 0.319847452667973 | ABCG8, ATP2B4, ATP1A3, ABCD4, ABCC2 | 112 | 334 | 12983 | 1.7353239948674 | 1 | 0.926524126740028 | 99.4965549903506
GOTERM_MF_FAT | GO:0042623~ATPase activity, coupled | 4 | 3.17460317460317 | 0.411968018355977 | ATP2B4, ATP1A3, ABCD4, ABCC2 | 112 | 272 | 12983 | 1.7047006302521 | 1 | 0.962617238623731 | 99.9317279387196
Annotation Cluster 30 | Enrichment Score: 0.9228675188833584 | protein ubiquitination
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0016567~protein ubiquitination | 4 | 3.17460317460317 | 0.0891693909827058 | [NAME], UBE4A, CBLL1, HDAC6 | 121 | 119 | 13528 | 3.75803875269115 | 1 | 0.749291129318555 | 78.6009272507104
GOTERM_BP_FAT | GO:0032446~protein modification by small protein conjugation | 4 | 3.17460317460317 | 0.112600387293676 | [NAME], UBE4A, CBLL1, HDAC6 | 121 | 132 | 13528 | 3.38792887553218 | 1 | 0.795581980172774 | 86.0828354547054
GOTERM_BP_FAT | [NAME]~protein modification by small protein conjugation or removal | 4 | 3.17460317460317 | 0.169684338058916 | [NAME], UBE4A, CBLL1, HDAC6 | 121 | 160 | 13528 | 2.79504132231404 | 1 | 0.858953594767846 | 95.3562930908413
Annotation Cluster 31 | Enrichment Score: 0.8925873314944036
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | serine/threonine-protein kinase | 6 | 4.76190476190476 | 0.102956107883921 | PSKH2, TP53RK, CSNK1A1, ACVR2A, [NAME], PRKAA2 | 126 | 381 | 19235 | 2.40407449068866 | 0.999999999999868 | 0.532592308912408 | 76.0930954785777
INTERPRO | IPR017441:Protein kinase, ATP binding site | 7 | 5.55555555555555 | 0.117419543561558 | PSKH2, TP53RK, CSNK1A1, ACVR2A, LCK, [NAME], PRKAA2 | 123 | 455 | 16659 | 2.08367729831144 | 1 | 0.970298725441166 | 82.0871673558296
INTERPRO | IPR000719:Protein kinase, core | 7 | 5.55555555555555 | 0.13688041358544 | PSKH2, TP53RK, CSNK1A1, ACVR2A, LCK, [NAME], PRKAA2 | 123 | 476 | 16659 | 1.99175035868005 | 1 | 0.978683664189479 | 86.8220605187948
GOTERM_MF_FAT | GO:0004674~protein serine/threonine kinase activity | 7 | 5.55555555555555 | 0.162523759972351 | PSKH2, TP53RK, CSNK1A1, ACVR2A, ITGAE, [NAME], PRKAA2 | 112 | 430 | 12983 | 1.88706395348837 | 1 | 0.837849656634337 | 91.2393712096849
Annotation Cluster 32 | Enrichment Score: 0.8426153576454304
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0006886~intracellular protein transport | 7 | 5.55555555555555 | 0.115443547361309 | STX2, GRIK2, IPO5, [NAME], [NAME], [NAME], HDAC6 | 121 | 374 | 13528 | 2.09254430547575 | 1 | 0.798168739678185 | 86.800914202099
GOTERM_BP_FAT | GO:0034613~cellular protein localization | 7 | 5.55555555555555 | 0.158415103485755 | STX2, GRIK2, IPO5, [NAME], [NAME], [NAME], HDAC6 | 121 | 411 | 13528 | 1.90416440449618 | 1 | 0.857216944835707 | 94.1988457522799
GOTERM_BP_FAT | [NAME]~cellular macromolecule localization | 7 | 5.55555555555555 | 0.162176408456331 | STX2, GRIK2, IPO5, [NAME], [NAME], [NAME], HDAC6 | 121 | 414 | 13528 | 1.89036611170998 | 1 | 0.855653084518206 | 94.612335364712
Annotation Cluster 33 | Enrichment Score: 0.8272452055258017
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0032675~regulation of interleukin-6 production | 3 | 2.38095238095238 | 0.0404094933638937 | TLR3, IL6R, TLR6 | 121 | 36 | 13528 | 9.31680440771349 | 1 | 0.65577675582617 | 49.3855872373559
GOTERM_BP_FAT | GO:0043408~regulation of MAPKKK cascade | 4 | 3.17460317460317 | 0.0727434607989771 | GRIK2, TLR3, IL6R, TLR6 | 121 | 109 | 13528 | 4.10281295018576 | 1 | 0.738796912078506 | 71.2568052797027
GOTERM_BP_FAT | GO:0010740~positive regulation of protein kinase cascade | 4 | 3.17460317460317 | 0.185086652649031 | [NAME], TLR3, IL6R, TLR6 | 121 | 167 | 13528 | 2.67788390161825 | 1 | 0.861917338314357 | 96.591017117561
GOTERM_BP_FAT | GO:0042742~defense response to bacterium | 3 | 2.38095238095238 | 0.261809165886389 | TLR3, IL6R, TLR6 | 121 | 112 | 13528 | 2.99468713105076 | 1 | 0.901796254113032 | 99.3336167586273
GOTERM_BP_FAT | GO:0009617~response to bacterium | 3 | 2.38095238095238 | 0.513022791844969 | TLR3, IL6R, TLR6 | 121 | 193 | 13528 | 1.73784952682738 | 1 | 0.98464412348118 | 99.999305962209
Annotation Cluster 34 | Enrichment Score: 0.8202801733989088 | membrane-bound vesicle
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0031988~membrane-bounded vesicle | 9 | 7.14285714285714 | 0.10753492221963 | RAB2A, HSP90AA1, [NAME], STX2, HGF, TRH, BMP7, RACGAP1, ITGB1 | 109 | 568 | 12782 | 1.85808890037472 | 0.999999999966477 | 0.64958713404587 | 76.2968087574699
GOTERM_CC_FAT | GO:0031410~cytoplasmic vesicle | 9 | 7.14285714285714 | 0.175471155987406 | RAB2A, HSP90AA1, [NAME], STX2, HGF, TRH, TLR6, RACGAP1, ITGB1 | 109 | 642 | 12782 | 1.64391665952156 | 1 | 0.744227002040749 | 91.2961397680665
GOTERM_CC_FAT | GO:0016023~cytoplasmic membrane-bounded vesicle | 8 | 6.34920634920634 | 0.183402063328214 | RAB2A, HSP90AA1, [NAME], STX2, HGF, TRH, RACGAP1, ITGB1 | 109 | 550 | 12782 | 1.70568807339449 | 1 | 0.738750875721252 | 92.2980985942079
Annotation Cluster 35 | Enrichment Score: 0.774607426511288
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
KEGG_PATHWAY | hsa05211:[NAME] cell carcinoma | 4 | 3.17460317460317 | 0.0595732638547741 | HRAS, PIK3CB, PIK3CA, HGF | 66 | 70 | 5085 | 4.4025974025974 | 0.998512535674584 | 0.418739854133556 | 49.8028638824319
KEGG_PATHWAY | hsa05218:Melanoma | 4 | 3.17460317460317 | 0.0616520235629783 | HRAS, PIK3CB, PIK3CA, HGF | 66 | 71 | 5085 | 4.34058898847631 | 0.998823543949301 | 0.40480445782273 | 51.033955050208
KEGG_PATHWAY | hsa05213:Endometrial cancer | 3 | 2.38095238095238 | 0.142266135999109 | HRAS, PIK3CB, PIK3CA | 66 | 52 | 5085 | 4.44493006993007 | 0.99999991382704 | 0.492261075489431 | 82.1290459479589
KEGG_PATHWAY | hsa05223:Non-small cell lung cancer | 3 | 2.38095238095238 | 0.151125867044349 | HRAS, PIK3CB, PIK3CA | 66 | 54 | 5085 | 4.28030303030303 | 0.999999971332502 | 0.500775843902666 | 84.0944284557655
KEGG_PATHWAY | hsa04660:T cell receptor signaling pathway | 4 | 3.17460317460317 | 0.15920558916783 | HRAS, PIK3CB, LCK, PIK3CA | 66 | 108 | 5085 | 2.85353535353535 | 0.999999989597912 | 0.506864607424142 | 85.712937108869
KEGG_PATHWAY | hsa05221:Acute myeloid leukemia | 3 | 2.38095238095238 | 0.169160241660182 | HRAS, PIK3CB, PIK3CA | 66 | 58 | 5085 | 3.98510971786833 | 0.999999997056725 | 0.516906975539821 | 87.5002385609611
KEGG_PATHWAY | hsa05214:[NAME] | 3 | 2.38095238095238 | 0.192184590254716 | HRAS, PIK3CB, PIK3CA | 66 | 63 | 5085 | 3.66883116883116 | 0.999999999850346 | 0.541636668791542 | 90.8809910775495
KEGG_PATHWAY | hsa04662:B cell receptor signaling pathway | 3 | 2.38095238095238 | 0.248793558057121 | HRAS, PIK3CB, PIK3CA | 66 | 75 | 5085 | 3.08181818181818 | 0.999999999999932 | 0.601045081591573 | 95.9645430303585
KEGG_PATHWAY | hsa05220:Chronic myeloid leukemia | 3 | 2.38095238095238 | 0.248793558057121 | HRAS, PIK3CB, PIK3CA | 66 | 75 | 5085 | 3.08181818181818 | 0.999999999999932 | 0.601045081591573 | 95.9645430303585
KEGG_PATHWAY | hsa04370:VEGF signaling pathway | 3 | 2.38095238095238 | 0.248793558057121 | HRAS, PIK3CB, PIK3CA | 66 | 75 | 5085 | 3.08181818181818 | 0.999999999999932 | 0.601045081591573 | 95.9645430303585
KEGG_PATHWAY | hsa04664:Fc epsilon RI signaling pathway | 3 | 2.38095238095238 | 0.263091440685 | HRAS, PIK3CB, PIK3CA | 66 | 78 | 5085 | 2.96328671328671 | 0.999999999999991 | 0.613951025639626 | 96.7472893692796
KEGG_PATHWAY | hsa04012:ErbB signaling pathway | 3 | 2.38095238095238 | 0.305965548687354 | HRAS, PIK3CB, PIK3CA | 66 | 87 | 5085 | 2.65673981191222 | 1 | 0.648780934407817 | 98.3399031274635
Annotation Cluster 36 | Enrichment Score: 0.7568734534900001
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | [NAME]~regulation of T cell activation | 4 | 3.17460317460317 | 0.0857677462092699 | LCK, CD2, GLMN, IL21 | 121 | 117 | 13528 | 3.82227873136964 | 1 | 0.749925419967063 | 77.2427296177223
GOTERM_BP_FAT | GO:0051249~regulation of lymphocyte activation | 4 | 3.17460317460317 | 0.144245885050009 | LCK, CD2, GLMN, IL21 | 121 | 148 | 13528 | 3.02166629439356 | 1 | 0.846980044182655 | 92.3578565507543
GOTERM_BP_FAT | GO:0002694~regulation of leukocyte activation | 4 | 3.17460317460317 | 0.182863468992396 | LCK, CD2, GLMN, IL21 | 121 | 166 | 13528 | 2.69401573235089 | 1 | 0.861998923053457 | 96.4341994580092
GOTERM_BP_FAT | GO:0050865~regulation of cell activation | 4 | 3.17460317460317 | 0.203121249588183 | LCK, CD2, GLMN, IL21 | 121 | 175 | 13528 | 2.55546635182998 | 1 | 0.873772960383845 | 97.643973231902
GOTERM_BP_FAT | GO:0002696~positive regulation of leukocyte activation | 3 | 2.38095238095238 | 0.242079703465933 | LCK, CD2, IL21 | 121 | 106 | 13528 | 3.16419772337439 | 1 | 0.893484478513422 | 98.970036774557
GOTERM_BP_FAT | GO:0050867~positive regulation of cell activation | 3 | 2.38095238095238 | 0.258518219328273 | LCK, CD2, IL21 | 121 | 111 | 13528 | 3.02166629439356 | 1 | 0.900893382205393 | 99.282841961276
Annotation Cluster 37 | Enrichment Score: 0.7439865728648091 | apoptosis
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | [NAME]~apoptosis | 9 | 7.14285714285714 | 0.165803558004341 | BAG4, HRAS, UNC5B, GRIK2, TP53BP2, GZMA, LCK, RHOB, BIRC3 | 121 | 602 | 13528 | 1.67145328244694 | 1 | 0.856046466680959 | 94.9847190537854
GOTERM_BP_FAT | GO:0012501~programmed cell death | 9 | 7.14285714285714 | 0.17538504781901 | BAG4, HRAS, UNC5B, GRIK2, TP53BP2, GZMA, LCK, RHOB, BIRC3 | 121 | 611 | 13528 | 1.64683285766457 | 1 | 0.860930544273498 | 95.8554978612995
GOTERM_BP_FAT | GO:0008219~cell death | 10 | 7.93650793650793 | 0.188064708941707 | BAG4, HRAS, KLK8, UNC5B, GRIK2, TP53BP2, GZMA, LCK, RHOB, BIRC3 | 121 | 719 | 13528 | 1.55496040184369 | 1 | 0.861240397153625 | 96.7909473266817
GOTERM_BP_FAT | GO:0016265~death | 10 | 7.93650793650793 | 0.193268017128436 | BAG4, HRAS, KLK8, UNC5B, GRIK2, TP53BP2, GZMA, LCK, RHOB, BIRC3 | 121 | 724 | 13528 | 1.54422172503538 | 1 | 0.862355162381684 | 97.1140815604234
Annotation Cluster 38 | Enrichment Score: 0.7372530478925399
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | ionic channel | 6 | 4.76190476190476 | 0.0567022671234314 | TRPC1, GRIK2, PKD2, CACNA1E, [NAME], KCNE3 | 126 | 318 | 19235 | 2.88035339922132 | 0.999999880016963 | 0.401938560831859 | 53.6439048544363
GOTERM_MF_FAT | GO:0022836~gated channel activity | 6 | 4.76190476190476 | 0.126556863403028 | TRPC1, GRIK2, PKD2, CACNA1E, [NAME], KCNE3 | 112 | 310 | 12983 | 2.24360599078341 | 1 | 0.823581514277336 | 84.3956621878154
GOTERM_MF_FAT | GO:0005261~cation channel activity | 5 | 3.96825396825396 | 0.209081278989232 | TRPC1, PKD2, CACNA1E, [NAME], KCNE3 | 112 | 275 | 12983 | 2.10762987012987 | 1 | 0.878175846553976 | 96.0050352996129
GOTERM_MF_FAT | GO:0005216~ion channel activity | 6 | 4.76190476190476 | 0.234905252343791 | TRPC1, GRIK2, PKD2, CACNA1E, [NAME], KCNE3 | 112 | 386 | 12983 | 1.80185973353071 | 1 | 0.893055782646067 | 97.4672311426125
GOTERM_MF_FAT | [NAME]substrate specific channel activity | 6 | 4.76190476190476 | 0.254062697713617 | TRPC1, GRIK2, PKD2, CACNA1E, [NAME], KCNE3 | 112 | 398 | 12983 | 1.74753230437903 | 1 | 0.908511458989265 | 98.2118411976514
GOTERM_MF_FAT | GO:0015267~channel activity | 6 | 4.76190476190476 | 0.27689079304232 | TRPC1, GRIK2, PKD2, CACNA1E, [NAME], KCNE3 | 112 | 412 | 12983 | 1.68815013869625 | 1 | 0.924706075871078 | 98.8329374768261
GOTERM_MF_FAT | GO:0022803~passive transmembrane transporter activity | 6 | 4.76190476190476 | 0.278538506420463 | TRPC1, GRIK2, PKD2, CACNA1E, [NAME], KCNE3 | 112 | 413 | 12983 | 1.68406260809408 | 1 | 0.921756880628324 | 98.8689210571116
Annotation Cluster 39 | Enrichment Score: 0.7306040444877746
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0051384~response to glucocorticoid stimulus | 3 | 2.38095238095238 | 0.152194012973304 | AVPR1A, IL6R, TRH | 121 | 78 | 13528 | 4.30006357279084 | 1 | 0.856340125695239 | 93.448871588404
GOTERM_BP_FAT | GO:0031960~response to corticosteroid stimulus | 3 | 2.38095238095238 | 0.174093150694871 | AVPR1A, IL6R, TRH | 121 | 85 | 13528 | 3.94594069032571 | 1 | 0.860675071551515 | 95.7469982823068
GOTERM_BP_FAT | GO:0048545~response to steroid hormone stimulus | 4 | 3.17460317460317 | 0.242665822041353 | AVPR1A, IL6R, TRH, BMP7 | 121 | 192 | 13528 | 2.32920110192837 | 1 | 0.892796613148097 | 98.9831068069218
Annotation Cluster 40 | Enrichment Score: 0.6789849948917038
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0030326~embryonic limb morphogenesis | 3 | 2.38095238095238 | 0.180442458864656 | GNAQ, GNAS, FLVCR1 | 121 | 87 | 13528 | 3.85522941008834 | 1 | 0.859848717399711 | 96.2557316751443
GOTERM_BP_FAT | GO:0035113~embryonic appendage morphogenesis | 3 | 2.38095238095238 | 0.180442458864656 | GNAQ, GNAS, FLVCR1 | 121 | 87 | 13528 | 3.85522941008834 | 1 | 0.859848717399711 | 96.2557316751443
GOTERM_BP_FAT | GO:0035107~appendage morphogenesis | 3 | 2.38095238095238 | 0.219164148423897 | GNAQ, GNAS, FLVCR1 | 121 | 99 | 13528 | 3.38792887553218 | 1 | 0.878339541335361 | 98.3158799988744
GOTERM_BP_FAT | GO:0035108~limb morphogenesis | 3 | 2.38095238095238 | 0.219164148423897 | GNAQ, GNAS, FLVCR1 | 121 | 99 | 13528 | 3.38792887553218 | 1 | 0.878339541335361 | 98.3158799988744
GOTERM_BP_FAT | GO:0060173~limb development | 3 | 2.38095238095238 | 0.232239862905168 | GNAQ, GNAS, FLVCR1 | 121 | 103 | 13528 | 3.25635882211345 | 1 | 0.884650483598321 | 98.7256167116385
GOTERM_BP_FAT | [NAME] | 3 | 2.38095238095238 | 0.232239862905168 | GNAQ, GNAS, FLVCR1 | 121 | 103 | 13528 | 3.25635882211345 | 1 | 0.884650483598321 | 98.7256167116385
Annotation Cluster 41 | Enrichment Score: 0.673979447348251
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | [NAME]negative regulation of apoptosis | 6 | 4.76190476190476 | 0.206088807515044 | BAG4, HRAS, GRIK2, PIK3CA, HGF, BIRC3 | 121 | 354 | 13528 | 1.89494326936545 | 1 | 0.87305353584512 | 97.7847032768326
GOTERM_BP_FAT | GO:0043069~negative regulation of programmed cell death | 6 | 4.76190476190476 | 0.213990280800508 | BAG4, HRAS, GRIK2, PIK3CA, HGF, BIRC3 | 121 | 359 | 13528 | 1.86855130182554 | 1 | 0.87446096991963 | 98.1218906135215
GOTERM_BP_FAT | GO:0060548~negative regulation of cell death | 6 | 4.76190476190476 | 0.21558235064204 | BAG4, HRAS, GRIK2, PIK3CA, HGF, BIRC3 | 121 | 360 | 13528 | 1.86336088154269 | 1 | 0.875070585017293 | 98.1837125584083
Annotation Cluster 42 | Enrichment Score: 0.6535952041565265
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0022843~voltage-gated cation channel activity | 4 | 3.17460317460317 | 0.131368878496428 | PKD2, CACNA1E, [NAME], KCNE3 | 112 | 147 | 12983 | 3.15427599611273 | 1 | 0.825086128472541 | 85.535365871743
GOTERM_MF_FAT | GO:0005261~cation channel activity | 5 | 3.96825396825396 | 0.209081278989232 | TRPC1, PKD2, CACNA1E, [NAME], KCNE3 | 112 | 275 | 12983 | 2.10762987012987 | 1 | 0.878175846553976 | 96.0050352996129
GOTERM_MF_FAT | GO:0022832~voltage-gated channel activity | 4 | 3.17460317460317 | 0.233073311382685 | PKD2, CACNA1E, [NAME], KCNE3 | 112 | 195 | 12983 | 2.37783882783882 | 1 | 0.896504891621722 | 97.3826952150599
GOTERM_MF_FAT | GO:0005244~voltage-gated ion channel activity | 4 | 3.17460317460317 | 0.233073311382685 | PKD2, CACNA1E, [NAME], KCNE3 | 112 | 195 | 12983 | 2.37783882783882 | 1 | 0.896504891621722 | 97.3826952150599
SP_PIR_KEYWORDS | voltage-gated channel | 3 | 2.38095238095238 | 0.254886823642073 | CACNA1E, [NAME], KCNE3 | 126 | 150 | 19235 | 3.0531746031746 | 1 | 0.767855883733989 | 97.9247157297543
GOTERM_MF_FAT | GO:0005267~potassium channel activity | 3 | 2.38095238095238 | 0.314984118007786 | PKD2, [NAME], KCNE3 | 112 | 133 | 12983 | 2.61472878625134 | 1 | 0.930263303184807 | 99.4448223143425
Annotation Cluster 43 | Enrichment Score: 0.5987848526129242
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0030384~phosphoinositide metabolic process | 3 | 2.38095238095238 | 0.136922168347161 | PIGK, PIK3CB, PIK3CA | 121 | 73 | 13528 | 4.59458847503679 | 1 | 0.838101108389596 | 91.2034811381448
GOTERM_BP_FAT | GO:0006644~phospholipid metabolic process | 4 | 3.17460317460317 | 0.237942506599137 | PIGK, PIK3CB, PIK3CA, [NAME] | 121 | 190 | 13528 | 2.35371900826446 | 1 | 0.890082693886329 | 98.8731917614318
GOTERM_BP_FAT | GO:0019637~organophosphate metabolic process | 4 | 3.17460317460317 | 0.261706243778786 | PIGK, PIK3CB, PIK3CA, [NAME] | 121 | 200 | 13528 | 2.23603305785123 | 1 | 0.902916484860116 | 99.3320813325112
GOTERM_BP_FAT | [NAME]glycerophospholipid metabolic process | 3 | 2.38095238095238 | 0.281555027037283 | PIGK, PIK3CB, PIK3CA | 121 | 118 | 13528 | 2.84241490404818 | 1 | 0.91581808552481 | 99.5740685274634
GOTERM_BP_FAT | GO:0046486~glycerolipid metabolic process | 3 | 2.38095238095238 | 0.422427872952204 | PIGK, PIK3CB, PIK3CA | 121 | 162 | 13528 | 2.07040097949188 | 1 | 0.966912164449426 | 99.9883965165154
Annotation Cluster 44 | Enrichment Score: 0.5670711444823554
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0001934~positive regulation of protein amino acid phosphorylation | 3 | 2.38095238095238 | 0.186826703112496 | ACVR2A, IL6R, BMP7 | 121 | 89 | 13528 | 3.76859504132231 | 1 | 0.862902479888352 | 96.7092109216791
GOTERM_BP_FAT | GO:0031401~positive regulation of protein modification process | 4 | 3.17460317460317 | 0.230889174029908 | ACVR2A, PSMA3, IL6R, BMP7 | 121 | 187 | 13528 | 2.39147920625801 | 1 | 0.884423776165929 | 98.6880970070343
GOTERM_BP_FAT | GO:0032270~positive regulation of cellular protein metabolic process | 4 | 3.17460317460317 | 0.341614127224992 | ACVR2A, PSMA3, IL6R, BMP7 | 121 | 233 | 13528 | 1.919341680559 | 1 | 0.944154680941515 | 99.899197646947
GOTERM_BP_FAT | GO:0051247~positive regulation of protein metabolic process | 4 | 3.17460317460317 | 0.365878659811527 | ACVR2A, PSMA3, IL6R, BMP7 | 121 | 243 | 13528 | 1.84035642621501 | 1 | 0.951531104454217 | 99.945768016297
Annotation Cluster 45 | Enrichment Score: 0.5253310309765332
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | potassium transport | 3 | 2.38095238095238 | 0.171843930184544 | ATP1A3, [NAME], KCNE3 | 126 | 115 | 19235 | 3.98240165631469 | 1 | 0.681423344699384 | 91.6539636637204
SP_PIR_KEYWORDS | potassium | 3 | 2.38095238095238 | 0.197555000305062 | ATP1A3, [NAME], KCNE3 | 126 | 126 | 19235 | 3.63473167044595 | 1 | 0.699318019340302 | 94.4908787065367
GOTERM_MF_FAT | GO:0030955~potassium ion binding | 3 | 2.38095238095238 | 0.299203691409197 | ATP1A3, [NAME], KCNE3 | 112 | 128 | 12983 | 2.71686662946428 | 1 | 0.92999075744571 | 99.2410347170592
GOTERM_MF_FAT | GO:0031420~alkali metal ion binding | 4 | 3.17460317460317 | 0.309397509158896 | SLC9A8, ATP1A3, [NAME], KCNE3 | 112 | 228 | 12983 | 2.03367794486215 | 1 | 0.929909679128432 | 99.3793325869623
GOTERM_BP_FAT | GO:0006813~potassium ion transport | 3 | 2.38095238095238 | 0.416286891614622 | ATP1A3, [NAME], KCNE3 | 121 | 160 | 13528 | 2.09628099173553 | 1 | 0.965180473369381 | 99.9861830113885
GOTERM_BP_FAT | GO:0015672~monovalent inorganic cation transport | 4 | 3.17460317460317 | 0.538660456509812 | SLC9A8, ATP1A3, [NAME], KCNE3 | 121 | 318 | 13528 | 1.4063100992775 | 1 | 0.986846391305997 | 99.999715787441
Annotation Cluster 46 | Enrichment Score: 0.5233202121276568
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0048858~cell projection morphogenesis | 5 | 3.96825396825396 | 0.173195728424002 | OFD1, KLK8, UNC5B, TNN, BMP7 | 121 | 245 | 13528 | 2.28166638556248 | 1 | 0.861108291140667 | 95.670064069091
GOTERM_BP_FAT | GO:0032990~cell part morphogenesis | 5 | 3.96825396825396 | 0.192657921046509 | OFD1, KLK8, UNC5B, TNN, BMP7 | 121 | 256 | 13528 | 2.18362603305785 | 1 | 0.863169695146673 | 97.077840839641
GOTERM_BP_FAT | GO:0000902~cell morphogenesis | 6 | 4.76190476190476 | 0.209237455950051 | OFD1, KLK8, UNC5B, TNN, HGF, BMP7 | 121 | 356 | 13528 | 1.88429752066115 | 1 | 0.872628801870008 | 97.9253646472992
GOTERM_BP_FAT | [NAME]~cell projection organization | 6 | 4.76190476190476 | 0.228453217638875 | OFD1, KLK8, UNC5B, STX2, TNN, BMP7 | 121 | 368 | 13528 | 1.82285303629177 | 1 | 0.887217054654511 | 98.6177937265547
GOTERM_BP_FAT | GO:0048812~neuron projection morphogenesis | 4 | 3.17460317460317 | 0.293023820654629 | KLK8, UNC5B, TNN, BMP7 | 121 | 213 | 13528 | 2.09956155666783 | 1 | 0.918160601321959 | 99.6734350443615
GOTERM_BP_FAT | GO:0000904~cell morphogenesis involved in differentiation | 4 | 3.17460317460317 | 0.368298783312934 | UNC5B, TNN, HGF, BMP7 | 121 | 244 | 13528 | 1.83281398184527 | 1 | 0.952071509548199 | 99.9490855167741
GOTERM_BP_FAT | [NAME]neuron projection development | 4 | 3.17460317460317 | 0.397201069475941 | KLK8, UNC5B, TNN, BMP7 | 121 | 256 | 13528 | 1.74690082644628 | 1 | 0.95977576868348 | 99.9764993135567
GOTERM_BP_FAT | GO:0007409~axonogenesis | 3 | 2.38095238095238 | 0.513022791844969 | UNC5B, TNN, BMP7 | 121 | 193 | 13528 | 1.73784952682738 | 1 | 0.98464412348118 | 99.999305962209
GOTERM_BP_FAT | GO:0048667~cell morphogenesis involved in neuron differentiation | 3 | 2.38095238095238 | 0.55604130593597 | UNC5B, TNN, BMP7 | 121 | 209 | 13528 | 1.60480841472577 | 1 | 0.988417877927065 | 99.9998492280967
Annotation Cluster 47 | Enrichment Score: 0.47464909059049143
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0009165~nucleotide biosynthetic process | 4 | 3.17460317460317 | 0.22854700878818 | TYMS, [NAME], ATP2B4, ATP1A3 | 121 | 186 | 13528 | 2.40433662134541 | 1 | 0.885876038586743 | 98.6205648660657
GOTERM_BP_FAT | GO:0034654~nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process | 4 | 3.17460317460317 | 0.245033430432831 | TYMS, [NAME], ATP2B4, ATP1A3 | 121 | 193 | 13528 | 2.31713270243651 | 1 | 0.892788480819646 | 99.0343335673852
GOTERM_BP_FAT | GO:0034404~nucleobase, nucleoside and nucleotide biosynthetic process | 4 | 3.17460317460317 | 0.245033430432831 | TYMS, [NAME], ATP2B4, ATP1A3 | 121 | 193 | 13528 | 2.31713270243651 | 1 | 0.892788480819646 | 99.0343335673852
GOTERM_BP_FAT | GO:0006164~purine nucleotide biosynthetic process | 3 | 2.38095238095238 | 0.378800327440243 | [NAME], ATP2B4, ATP1A3 | 121 | 148 | 13528 | 2.26624972079517 | 1 | 0.95520180512525 | 99.9613940090115
GOTERM_BP_FAT | GO:0006163~purine nucleotide metabolic process | 3 | 2.38095238095238 | 0.493370471929263 | [NAME], ATP2B4, ATP1A3 | 121 | 186 | 13528 | 1.80325246600906 | 1 | 0.981602805243459 | 99.9986664115401
GOTERM_BP_FAT | GO:0044271~nitrogen compound biosynthetic process | 4 | 3.17460317460317 | 0.55347210240146 | TYMS, [NAME], ATP2B4, ATP1A3 | 121 | 325 | 13528 | 1.37602034329307 | 1 | 0.988248433633618 | 99.9998341597012
Annotation Cluster 48 | Enrichment Score: 0.46342149829047 | metalloprotein
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | metalloprotein | 3 | 2.38095238095238 | 0.193422687958376 | CYP1B1, AOX1, ACP5 | 126 | 124 | 19235 | 3.69335637480798 | 1 | 0.705524522461533 | 94.1052883888985
SP_PIR_KEYWORDS | iron | 4 | 3.17460317460317 | 0.282916480335837 | CYP1B1, AOX1, ACP5, RPE65 | 126 | 285 | 19235 | 2.14257866889445 | 1 | 0.779787319324602 | 98.7475727761485
GOTERM_MF_FAT | GO:0005506~iron ion binding | 3 | 2.38095238095238 | 0.743994704308799 | CYP1B1, AOX1, ACP5 | 112 | 308 | 12983 | 1.12908743042671 | 1 | 0.999460845260953 | 99.9999992480266
Annotation Cluster 49 | Enrichment Score: 0.4123869580518085
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0044432~endoplasmic reticulum part | 5 | 3.96825396825396 | 0.337204023335872 | PIGK, CYP1B1, TOR1A, [NAME], [NAME] | 109 | 347 | 12782 | 1.68971260873013 | 1 | 0.893084847958171 | 99.4506709695324
GOTERM_CC_FAT | GO:0005789~endoplasmic reticulum membrane | 4 | 3.17460317460317 | 0.397811986844092 | PIGK, [NAME], [NAME], [NAME] | 109 | 269 | 12782 | 1.7437331605334 | 1 | 0.908316015484517 | 99.8367537447159
GOTERM_CC_FAT | GO:0042175~nuclear envelope-endoplasmic reticulum network | 4 | 3.17460317460317 | 0.431785956337385 | PIGK, [NAME], [NAME], [NAME] | 109 | 284 | 12782 | 1.65163457811086 | 1 | 0.917631497333639 | 99.92170744024
Annotation Cluster 50 | Enrichment Score: 0.4034121237336182
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0016879~ligase activity, forming carbon-nitrogen bonds | 4 | 3.17460317460317 | 0.316427923949308 | UBE4A, ACACA, CBLL1, BIRC3 | 112 | 231 | 12983 | 2.00726654298082 | 1 | 0.927660364199424 | 99.4606728393191
GOTERM_MF_FAT | GO:0004842~ubiquitin-protein ligase activity | 3 | 2.38095238095238 | 0.358696400300313 | UBE4A, CBLL1, BIRC3 | 112 | 147 | 12983 | 2.36570699708454 | 1 | 0.94496334823422 | 99.7754607839965
GOTERM_MF_FAT | GO:0019787~small conjugating protein ligase activity | 3 | 2.38095238095238 | 0.416319592063557 | UBE4A, CBLL1, BIRC3 | 112 | 166 | 12983 | 2.09493330464716 | 1 | 0.962222342324105 | 99.9383465331766
GOTERM_MF_FAT | GO:0016881~acid-amino acid ligase activity | 3 | 2.38095238095238 | 0.51513710802413 | UBE4A, CBLL1, BIRC3 | 112 | 201 | 12983 | 1.73014392324093 | 1 | 0.985881446647558 | 99.9951688572399
Annotation Cluster 51 | Enrichment Score: 0.4024765429144758
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0043068~positive regulation of programmed cell death | 6 | 4.76190476190476 | 0.339422092374832 | GRIK2, TP53BP2, LCK, CD2, BMP7, HDAC6 | 121 | 433 | 13528 | 1.54921458973527 | 1 | 0.94365079851092 | 99.8935119933087
GOTERM_BP_FAT | GO:0010942~positive regulation of cell death | 6 | 4.76190476190476 | 0.342947583281961 | GRIK2, TP53BP2, LCK, CD2, BMP7, HDAC6 | 121 | 435 | 13528 | 1.54209176403533 | 1 | 0.944154083673476 | 99.9025154990206
GOTERM_BP_FAT | GO:0043065~positive regulation of apoptosis | 5 | 3.96825396825396 | 0.532846991592627 | TP53BP2, LCK, CD2, BMP7, HDAC6 | 121 | 430 | 13528 | 1.30001921968095 | 1 | 0.986360287900285 | 99.9996505205316
Annotation Cluster 52 | Enrichment Score: 0.4000137708766844
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0030097~hemopoiesis | 4 | 3.17460317460317 | 0.348903140518677 | LMO2, LCK, ITGB1, FLVCR1 | 121 | 236 | 13528 | 1.89494326936545 | 1 | 0.945283980551463 | 99.9161204780667
GOTERM_BP_FAT | GO:0048534~hemopoietic or lymphoid organ development | 4 | 3.17460317460317 | 0.406764076784263 | LMO2, LCK, ITGB1, FLVCR1 | 121 | 260 | 13528 | 1.72002542911633 | 1 | 0.962031383984539 | 99.9819518887306
GOTERM_BP_FAT | GO:0002520~immune system development | 4 | 3.17460317460317 | 0.44454038099176 | LMO2, LCK, ITGB1, FLVCR1 | 121 | 276 | 13528 | 1.62031381003713 | 1 | 0.972355224821782 | 99.9939086209418
Annotation Cluster 53 | Enrichment Score: 0.3851808928052902
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
INTERPRO | IPR008957:Fibronectin, type III-like fold | 3 | 2.38095238095238 | 0.39102015572332 | BZRAP1, TNN, IL6R | 123 | 184 | 16659 | 2.20824496288441 | 1 | 0.999976952302462 | 99.8917349338359
INTERPRO | IPR003961:Fibronectin, type III | 3 | 2.38095238095238 | 0.406470727408086 | BZRAP1, TNN, IL6R | 123 | 190 | 16659 | 2.1385109114249 | 1 | 0.999975264335895 | 99.9239970079873
SMART | SM00060:FN3 | 3 | 2.38095238095238 | 0.439773344647217 | BZRAP1, TNN, IL6R | 72 | 190 | 9079 | 1.99100877192982 | 1 | 0.99877479341705 | 99.791919897788
Annotation Cluster 54 | Enrichment Score: 0.36537957316474334 | vasculature development
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0001568~blood vessel development | 4 | 3.17460317460317 | 0.37071741622878 | LMO2, PLCD3, GLMN, RHOB | 121 | 245 | 13528 | 1.82533310844999 | 1 | 0.951934122057829 | 99.9522097895309
GOTERM_BP_FAT | GO:0001944~vasculature development | 4 | 3.17460317460317 | 0.385193364039079 | LMO2, PLCD3, GLMN, RHOB | 121 | 251 | 13528 | 1.78169964769023 | 1 | 0.956281867954819 | 99.9674546051432
GOTERM_BP_FAT | GO:0048514~blood vessel morphogenesis | 3 | 2.38095238095238 | 0.561228212141973 | PLCD3, GLMN, RHOB | 121 | 211 | 13528 | 1.58959696055775 | 1 | 0.988951053629199 | 99.9998758160177
Annotation Cluster 55 | Enrichment Score: 0.35192428502948814
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0051047~positive regulation of secretion | 3 | 2.38095238095238 | 0.251938733586997 | AVPR1A, GLMN, TRH | 121 | 109 | 13528 | 3.07710971263932 | 1 | 0.896474450448071 | 99.1702429233611
GOTERM_BP_FAT | GO:0051046~regulation of secretion | 3 | 2.38095238095238 | 0.537551629939636 | AVPR1A, GLMN, TRH | 121 | 202 | 13528 | 1.66042058751329 | 1 | 0.986894000658624 | 99.9997042981324
GOTERM_BP_FAT | GO:0060341~regulation of cellular localization | 3 | 2.38095238095238 | 0.649399604649627 | AVPR1A, GLMN, TRH | 121 | 248 | 13528 | 1.35243934950679 | 1 | 0.995911868546296 | 99.999996939803
Annotation Cluster 56 | Enrichment Score: 0.3516079530438995
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0048609~reproductive process in a multicellular organism | 6 | 4.76190476190476 | 0.434781313838594 | ACVR2A, AVPR1A, BIRC3, RACGAP1, ITGB1, C17ORF75 | 121 | 487 | 13528 | 1.37743309518556 | 1 | 0.970620009732334 | 99.991879501611
GOTERM_BP_FAT | [NAME]~multicellular organism reproduction | 6 | 4.76190476190476 | 0.434781313838594 | ACVR2A, AVPR1A, BIRC3, RACGAP1, ITGB1, C17ORF75 | 121 | 487 | 13528 | 1.37743309518556 | 1 | 0.970620009732334 | 99.991879501611
GOTERM_BP_FAT | GO:0007276~gamete generation | 5 | 3.96825396825396 | 0.466266699730322 | ACVR2A, [NAME], RACGAP1, ITGB1, C17ORF75 | 121 | 395 | 13528 | 1.41521079610837 | 1 | 0.976882237438401 | 99.9968474549093
Annotation Cluster 57 | Enrichment Score: 0.3268903135868097 | [NAME] process
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0009057~macromolecule catabolic process | 9 | 7.14285714285714 | 0.39007891223436 | PJA2, [NAME], [NAME], UBE4A, FBXO16, PSMA3, CBLL1, OAS2, HDAC6 | 121 | 781 | 13528 | 1.28836731886435 | 1 | 0.95787007638757 | 99.9714707131211
SP_PIR_KEYWORDS | ubl conjugation pathway | 5 | 3.96825396825396 | 0.422487999131349 | PJA2, [NAME], UBE4A, FBXO16, CBLL1 | 126 | 509 | 19235 | 1.49959459880874 | 1 | 0.900331882302137 | 99.9276244606082
GOTERM_BP_FAT | GO:0051603~proteolysis involved in cellular protein catabolic process | 7 | 5.55555555555555 | 0.441878106385487 | PJA2, [NAME], UBE4A, FBXO16, PSMA3, CBLL1, HDAC6 | 121 | 600 | 13528 | 1.30435261707988 | 1 | 0.971969954573548 | 99.9934083269425
GOTERM_BP_FAT | GO:0044257~cellular protein catabolic process | 7 | 5.55555555555555 | 0.446628740577329 | PJA2, [NAME], UBE4A, FBXO16, PSMA3, CBLL1, HDAC6 | 121 | 603 | 13528 | 1.297863300577 | 1 | 0.972563314688376 | 99.9942758598119
GOTERM_BP_FAT | GO:0044265~cellular macromolecule catabolic process | 8 | 6.34920634920634 | 0.464739335566052 | PJA2, [NAME], UBE4A, FBXO16, PSMA3, CBLL1, OAS2, HDAC6 | 121 | 725 | 13528 | 1.23367341122827 | 1 | 0.976853192936837 | 99.9966951766387
GOTERM_BP_FAT | GO:0030163~protein catabolic process | 7 | 5.55555555555555 | 0.476515325411155 | PJA2, [NAME], UBE4A, FBXO16, PSMA3, CBLL1, HDAC6 | 121 | 622 | 13528 | 1.25821795859796 | 1 | 0.978741263961091 | 99.9977109341854
GOTERM_BP_FAT | GO:0043632~modification-dependent macromolecule catabolic process | 6 | 4.76190476190476 | 0.580346797853228 | PJA2, [NAME], UBE4A, FBXO16, PSMA3, CBLL1 | 121 | 574 | 13528 | 1.16865839260517 | 1 | 0.990694251202139 | 99.9999404796236
GOTERM_BP_FAT | GO:0019941~modification-dependent protein catabolic process | 6 | 4.76190476190476 | 0.580346797853228 | PJA2, [NAME], UBE4A, FBXO16, PSMA3, CBLL1 | 121 | 574 | 13528 | 1.16865839260517 | 1 | 0.990694251202139 | 99.9999404796236
Annotation Cluster 58 | Enrichment Score: 0.3095800635890749
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0016477~cell migration | 4 | 3.17460317460317 | 0.44454038099176 | TNS1, TNN, IL6R, ITGB1 | 121 | 276 | 13528 | 1.62031381003713 | 1 | 0.972355224821782 | 99.9939086209418
GOTERM_BP_FAT | GO:0051674~localization of cell | 4 | 3.17460317460317 | 0.514842387873499 | TNS1, TNN, IL6R, ITGB1 | 121 | 307 | 13528 | 1.4566990604894 | 1 | 0.984715556028339 | 99.9993475539598
GOTERM_BP_FAT | GO:0048870~cell motility | 4 | 3.17460317460317 | 0.514842387873499 | TNS1, TNN, IL6R, ITGB1 | 121 | 307 | 13528 | 1.4566990604894 | 1 | 0.984715556028339 | 99.9993475539598
Annotation Cluster 59 | Enrichment Score: 0.3014423673391187
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0007276~gamete generation | 5 | 3.96825396825396 | 0.466266699730322 | ACVR2A, [NAME], RACGAP1, ITGB1, C17ORF75 | 121 | 395 | 13528 | 1.41521079610837 | 1 | 0.976882237438401 | 99.9968474549093
GOTERM_BP_FAT | GO:0048232~male gamete generation | 4 | 3.17460317460317 | 0.517034173847437 | ACVR2A, [NAME], RACGAP1, C17ORF75 | 121 | 308 | 13528 | 1.45196951808522 | 1 | 0.984596570207624 | 99.999394544237
GOTERM_BP_FAT | GO:0007283~spermatogenesis | 4 | 3.17460317460317 | 0.517034173847437 | ACVR2A, [NAME], RACGAP1, C17ORF75 | 121 | 308 | 13528 | 1.45196951808522 | 1 | 0.984596570207624 | 99.999394544237
Annotation Cluster 60 | Enrichment Score: 0.28934265940119724
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | ank repeat | 3 | 2.38095238095238 | 0.463679760560772 | TRPC1, TP53BP2, KIDINS220 | 126 | 240 | 19235 | 1.90823412698412 | 1 | 0.921022292883891 | 99.9726896459389
INTERPRO | IPR002110:Ankyrin | 3 | 2.38095238095238 | 0.522432144548094 | TRPC1, TP53BP2, KIDINS220 | 123 | 238 | 16659 | 1.70721459315433 | 1 | 0.999987256606893 | 99.9961887505469
SMART | SM00248:ANK | 3 | 2.38095238095238 | 0.559401970215881 | TRPC1, TP53BP2, KIDINS220 | 72 | 238 | 9079 | 1.58946078431372 | 1 | 0.999751153906857 | 99.9839141028778
Annotation Cluster 61 | Enrichment Score: 0.1918112144122423
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
INTERPRO | IPR017907:Zinc finger, RING-type, conserved site | 3 | 2.38095238095238 | 0.610861396835857 | PJA2, CBLL1, BIRC3 | 123 | 280 | 16659 | 1.45113240418118 | 1 | 0.999999002007722 | 99.9997726475569
INTERPRO | IPR001841:Zinc finger, RING-type | 3 | 2.38095238095238 | 0.641143633511478 | PJA2, CBLL1, BIRC3 | 123 | 296 | 16659 | 1.37269281476598 | 1 | 0.99999945718442 | 99.999925474774
SMART | SM00184:RING | 3 | 2.38095238095238 | 0.678685142223005 | PJA2, CBLL1, BIRC3 | 72 | 296 | 9079 | 1.27801238738738 | 1 | 0.999963492905307 | 99.9994438387917
Annotation Cluster 62 | Enrichment Score: 0.16399516464679237 | visual perception
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0050953~sensory perception of light stimulus | 3 | 2.38095238095238 | 0.574007674648562 | CYP1B1, RPE65, OAT | 121 | 216 | 13528 | 1.55280073461891 | 1 | 0.990086359384033 | 99.9999237651922
GOTERM_BP_FAT | GO:0007601~visual perception | 3 | 2.38095238095238 | 0.574007674648562 | CYP1B1, RPE65, OAT | 121 | 216 | 13528 | 1.55280073461891 | 1 | 0.990086359384033 | 99.9999237651922
GOTERM_BP_FAT | GO:0007600~sensory perception | 4 | 3.17460317460317 | 0.977640327630011 | CYP1B1, RPE65, GNAS, OAT | 121 | 810 | 13528 | 0.552106927864503 | 1 | 0.999999991399945 | 100
Annotation Cluster 63 | Enrichment Score: 0.11108290912418091 | oxidoreductase
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0009055~electron carrier activity | 3 | 2.38095238095238 | 0.566511831077769 | CYP1B1, ACADM, AOX1 | 112 | 221 | 12983 | 1.5735698125404 | 1 | 0.991462188831214 | 99.9989618096773
SP_PIR_KEYWORDS | oxidoreductase | 3 | 2.38095238095238 | 0.883845433922327 | CYP1B1, ACADM, AOX1 | 126 | 562 | 19235 | 0.814904253516353 | 1 | 0.999085111998635 | 99.9999999999514
GOTERM_BP_FAT | GO:0055114~oxidation reduction | 4 | 3.17460317460317 | 0.927184079559038 | TXNL1, CYP1B1, ACADM, AOX1 | 121 | 639 | 13528 | 0.69985385222261 | 1 | 0.999997695012873 | 100
Annotation Cluster 64 | Enrichment Score: 0.05586400797277905 | organelle lumen
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0043233~organelle lumen | 13 | 10.3174603174603 | 0.859820155526065 | IKBKAP, ACADM, ADARB1, POLI, E2F5, HDAC11, HGF, CCNE2, TOR1A, IPO5, PRKAA2, OAT, HDAC6 | 109 | 1820 | 12782 | 0.837614678899082 | 1 | 0.998352284681818 | 99.9999999984056
GOTERM_CC_FAT | GO:0031974~membrane-enclosed lumen | 13 | 10.3174603174603 | 0.877044658960098 | IKBKAP, ACADM, ADARB1, POLI, E2F5, HDAC11, HGF, CCNE2, TOR1A, IPO5, PRKAA2, OAT, HDAC6 | 109 | 1856 | 12782 | 0.821367842454919 | 1 | 0.99880832367556 | 99.9999999996965
GOTERM_CC_FAT | GO:0070013~intracellular organelle lumen | 12 | 9.52380952380952 | 0.901526810047255 | CCNE2, IKBKAP, ADARB1, POLI, ACADM, E2F5, IPO5, TOR1A, HDAC11, [NAME], OAT, HDAC6 | 109 | 1779 | 12782 | 0.791002057645002 | 1 | 0.999347353712291 | 99.9999999999817
Annotation Cluster 65 | Enrichment Score: 0.030012213580439973 | cation binding
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0046872~metal ion binding | 30 | 23.8095238095238 | 0.922840256261763 | SRI, SLC9A8, [NAME], CYP1B1, [NAME], ITGAE, ACP5, CBLL1, ATP2B4, PLCD3, PKD2, PRKAA2, KCNE3, TRPC1, POLI, ADARB1, ATP1A3, ACACA, RACGAP1, [NAME], [NAME], OC90, MMP12, PJA2, ACVR2A, MAN2C1, AOX1, CACNA1E, [NAME], HDAC6 | 112 | 4140 | 12983 | 0.839997412008281 | 1 | 0.999997632599836 | 99.9999999999999
GOTERM_MF_FAT | GO:0043169~cation binding | 30 | 23.8095238095238 | 0.932068231454492 | SRI, SLC9A8, [NAME], CYP1B1, [NAME], ITGAE, ACP5, CBLL1, ATP2B4, PLCD3, PKD2, PRKAA2, KCNE3, TRPC1, POLI, ADARB1, ATP1A3, ACACA, RACGAP1, [NAME], [NAME], OC90, MMP12, PJA2, ACVR2A, MAN2C1, AOX1, CACNA1E, [NAME], HDAC6 | 112 | 4179 | 12983 | 0.832158240180494 | 1 | 0.999998498290889 | 99.9999999999999
GOTERM_MF_FAT | GO:0043167~ion binding | 30 | 23.8095238095238 | 0.94490712198102 | SRI, SLC9A8, [NAME], CYP1B1, [NAME], ITGAE, ACP5, CBLL1, ATP2B4, PLCD3, PKD2, PRKAA2, KCNE3, TRPC1, POLI, ADARB1, ATP1A3, ACACA, RACGAP1, [NAME], [NAME], OC90, MMP12, PJA2, ACVR2A, MAN2C1, AOX1, CACNA1E, [NAME], HDAC6 | 112 | 4241 | 12983 | 0.819992757772762 | 1 | 0.999999355906513 | 100
Annotation Cluster 66 | Enrichment Score: 0.017279081033756468
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0044451~nucleoplasm part | 4 | 3.17460317460317 | 0.853741532990814 | IKBKAP, E2F5, HDAC11, HDAC6 | 109 | 555 | 12782 | 0.845160757087362 | 1 | 0.998449163684079 | 99.9999999972718
SP_PIR_KEYWORDS | transcription regulation | 5 | 3.96825396825396 | 0.999434243301379 | IKBKAP, E2F5, HDAC11, IRAK1BP1, HDAC6 | 126 | 2026 | 19235 | 0.376749087262413 | 1 | 0.999999999858862 | 100
SP_PIR_KEYWORDS | Transcription | 5 | 3.96825396825396 | 0.999563726755562 | IKBKAP, E2F5, HDAC11, IRAK1BP1, HDAC6 | 126 | 2071 | 19235 | 0.368562844419918 | 1 | 0.999999999916962 | 100
GOTERM_BP_FAT | GO:0006350~transcription | 6 | 4.76190476190476 | 0.999982853329985 | IKBKAP, E2F5, SKIL, HDAC11, IRAK1BP1, HDAC6 | 121 | 2101 | 13528 | 0.319281255285755 | 1 | 1 | 100
Annotation Cluster 67 | Enrichment Score: 3.0944213067729645E-5
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0030528~transcription regulator activity | 4 | 3.17460317460317 | 0.999875021942136 | IKBKAP, E2F5, SKIL, HDAC6 | 112 | 1512 | 12983 | 0.306665721844293 | 1 | 1 | 100
GOTERM_BP_FAT | GO:0006355~regulation of transcription, DNA-dependent | 5 | 3.96825396825396 | 0.999948180556564 | IKBKAP, E2F5, SKIL, BMP7, HDAC6 | 121 | 1773 | 13528 | 0.315289489262724 | 1 | 1 | 100
GOTERM_BP_FAT | GO:0051252~regulation of RNA metabolic process | 5 | 3.96825396825396 | 0.999963052285792 | IKBKAP, E2F5, SKIL, BMP7, HDAC6 | 121 | 1813 | 13528 | 0.308333295346282 | 1 | 1 | 100