Spreadsheet: 9eed7399-a3cc-476a-b123-d7c1c7c0dacf
Sheet: Sheet1

Table S3. Specific gene transcripts regulated at 7d and 14d post-treatment | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12
 | 7d |  |  |  | 14d
[NAME] | Systematic Oligo_ID | Model name | Fold Change | [NAME] | Systematic Oligo_ID | Model name | Fold Change | [NAME] | Annotation | Best Brugia CDS match or EST | Matching Pub_locus | C. elegans homolog
1 | bm.01196 | [NAME] | 0.20767213 | -2.267620478168733 | bm.01196 | [NAME] | 0.24763505 | -2.013712568370512 | cuticular collagen | [NAME]
2 | bm.00553 | BMC02185 | 0.37801868 | -1.403470567114322 | bm.00553 | BMC02185 | 0.46489707 | -1.105016761544553 | unknown | BMC02185
3 | bm.03169 | BMC00024 | 0.4250548 | -1.234279242833131 | bm.03169 | BMC00024 | 2.1657803 | 1.11488690122122 | ATP synthase F0 subunit 6 [Brugia malayi] | BMC00024
4 | [NAME] | TC2798 | 0.45155972 | -1.14701129422377 | [NAME] | TC2798 | 0.34077168 | -1.553122650230996 | cuticular collagen Bmcol-2 | TC2798
5 | [NAME] | [NAME] | 0.4529437 | -1.142596357592821 | [NAME] | [NAME] | 0.31606963 | -1.661685676390667 | [NAME] precursor (CPL-4), putative | 14514.m00011 | Bm1_20385 | CE22930
6 | bm.03295 | [NAME] | 2.007433 | 1.005351837216666 | bm.03295 | [NAME] | 3.2144876 | 1.684588785499029 | 60S ribosomal protein L10, putative | 14961.m05345 | Bm1_34250 | CE01543
7 | [NAME] | BMW01267.350 | 2.0091858 | 1.006610983854227 | [NAME] | BMW01267.350 | 0.3801908 | -1.395204473355829 | unknown | BMW01267.350
8 | BMX13047 | TC3046 | 2.0985057 | 1.069362381904101 | BMX11073 | W05384 | 2.0563464 | 1.04008331291086 | GTP-binding nuclear protein RAN/TC4, putative | 14979.m04454 | Bm1_44725 | CE16194
9 | bm.01688 | BMC11749 | 2.1114285 | 1.078219393508171 | BMX11189 | BMB_gene_8.247 | 2.9415224 | 1.556563022566319 | fructose-bisphosphate aldolase 1, putative | 14176.m00093 | Bm1_15350 | CE30646
10 | BMX10436 | AW179696 | 2.1492088 | 1.103805650327949 | BMX10436 | AW179696 | 2.2998805 | 1.201558901806065 | unknown | AW179696
11 | BMX13511, BMX12123 | TC3524, WB-contig_1287 | 2.17 | 1.117695042669755 | [NAME] | BMC05056 | 4.905132 | 2.294291960742782 | Vacuolar protein sorting-associated protein 45, putative | 14961.m05052 | Bm1_32805 | CE30898
12 | bm.00610 | BMC02427 | 2.2157044 | 1.147765422406886 | bm.00610 | BMC02427 | 2.5288246 | 1.338466974729212 | EF hand family protein | 15273.m00029 | Bm1_55540 | CE34292
13 | BMX2479 | 14232.m00275 | 2.2234852 | 1.152822801830115 | BMX2479 | 14232.m00275 | 2.1408546 | 1.098186815815825 | hypothetical protein | 14232.m00275 | Bm1_16160
14 | bm.01402 | BMC06617 | 2.2635827 | 1.178608016415814 | bm.01402 | BMC06617 | 4.478721 | 2.16308679692518 | Probable ATP-dependent RNA helicase p47 homolog, putative | 13367.m00046 | Bm1_08205 | CE26264
15 | [NAME] | BMC00826 | 2.300265 | 1.201800075153522 | [NAME] | BMC00826 | 2.1242616 | 1.086961443064398 | Elongation factor 1 gamma, conserved domain containing protein | 14992.m11155 | Bm1_51865 | CE32385
16 | [NAME] | BMC00748 | 2.334379 | 1.223038809987645 | BMX2805 | 14355.m00213 | 3.6970675 | 1.886381384078651 | 14-3-3-like protein 2, putative | 13662.m00125 | Bm1_10970 | CE36489
17 | BMX13142 | TC3144 | 2.3842542 | 1.253538058589028 | BMX13142 | TC3144 | 2.1741786 | 1.120470456809992 | 40S ribosomal protein S4, putative | 13260.m00097 | Bm1_06615 | CE24278
18 | BMX4257 | 14894.m00090 | 2.4110544 | 1.269664202464631 | BMX4257 | 14894.m00090 | 4.6241174 | 2.209178026352371 | elongation factor 1-alpha (EF-1-alpha), putative | 14894.m00090 | Bm1_27170 | CE32610
19 | BMX851 | 13183.m00070 | 2.4736862 | 1.306662498528746 | BMX851 | 13183.m00070 | 2.8026001 | 1.486765902448922 | proteasome subunit alpha type 6, putative | 13183.m00070 | Bm1_05700 | CE05371
20 | BMX10490 | AW561840 | 2.5277572 | 1.337857894219719 | BMX10490 | AW561840 | 2.1527781 | 1.10619961977078 | unknown | AW561840
21 | bm.00409 | BMC01550 | 2.5352864 | 1.342148731260504 | bm.00409 | BMC01550 | 2.3770347 | 1.249162963925075 | Eukaryotic translation initiation factor 5A-2, putative | 15549.m00017 | Bm1_57565 | CE37787
22 | bm.01565 | BMC07946 | 2.5805826 | 1.367696809542017 | bm.01565 | BMC07946 | 2.211568 | 1.145069602062275 | initiation factor 2-associated protein., putative | 14972.m07280 | Bm1_37925 | CE03743
23 | BMX13144 | TC3146 | 2.6056564 | 1.38164685263264 | BMX13144 | TC3146 | 2.3174274 | 1.212524143036098 | Ribosomal Protein, Small subunit family member (rps-20) [Caenorhabditis elegans] | TC3146
24 | bm.00430 | BMC01633 | 2.6827805 | 1.423729020861627 | bm.00430 | BMC01633 | 0.49158892 | -1.024475695940817 | gb|AAA16306.1| unknown | BMC01633
25 | BMX6958 | 14977.m04966 | 2.6884084 | 1.426752316650742 | BMX6958 | 14977.m04966 | 2.6973517 | 1.431543642732394 | hypothetical protein | 14977.m04966 | Bm1_43595 | CE27472
26 | BMX8336 | 14992.m11155 | 2.7170708 | 1.442052159037286 | BMX8336 | 14992.m11155 | 4.16002 | 2.056590464383545 | Elongation factor 1 gamma, conserved domain containing protein | 14992.m11155 | Bm1_51865 | CE32385
27 | BMX12900, bm00877 | TC2895, BMC03488 | 2.74 | 1.454175893185802 | [NAME] | BMC01632 | 4.5358186 | 2.181362944047007 | 60S ribosomal protein L5, putative | 14961.m04902 | Bm1_32050 | CE02255
28 | BMX5751 | 14972.m06982 | 2.7428956 | 1.455699711421105 | BMX5751 | 14972.m06982 | 3.4378731 | 1.78151629252407 | activated protein kinase C receptor RACK1 | 14972.m06982 | Bm1_36465 | CE00901
29 | BMX1802 | 13785.m00207 | 2.8771663 | 1.524648611154183 | BMX1802 | 13785.m00207 | 7.191897 | 2.846372359193115 | hypothetical protein | 13785.m00207 | Bm1_11840
30 | BMX2759 | 14325.m00128 | 2.9316907 | 1.551732903910257 | BMX2759 | 14325.m00128 | 3.9266443 | 1.973296915583056 | Mak16 protein | 14325.m00128 | Bm1_17915 | CE04006
31 | BMX3776 | 14707.m00118 | 2.9506884 | 1.561051576645768 | BMX12573 | WB-contig_338 | 2.6062243 | 1.38196125219937 | 6330505F04Rik protein, putative | 14707.m00118 | Bm1_24260
32 | BMX13551 | TC3568 | 2.9525495 | 1.561961246855588 | BMX13551 | TC3568 | 2.6441073 | 1.402780723758187 | La domain containing protein | 14612.m00130 | Bm1_22185 | CE08718
33 | BMX13034 | TC3032 | 2.9563184 | 1.563801658308002 | BMX13034 | TC3032 | 2.155559 | 1.108062051193047 | 40S ribosomal protein S23, putative | 14981.m02412 | Bm1_46875 | CE05747
34 | BMX12907 | TC2902 | 3.0418627 | 1.604955035869956 | BMX12907 | TC2902 | 2.722535 | 1.444950595866649 | GTP-binding protein SAR1, putative | 14972.m07055 | Bm1_36820 | CE02195
35 | bm.00164 | BMC00470 | 3.1382742 | 1.649971410208473 | bm.00164 | BMC00470 | 3.2992768 | 1.72214982101748 | heat shock 70 kDa protein, putative | 14977.m04983 | Bm1_43675 | CE02884
36 | BMX5155 | 14961.m05025 | 3.150101 | 1.655398085711969 | BMX5155 | 14961.m05025 | 2.722015 | 1.444675017013101 | hypothetical protein | 14961.m05025 | Bm1_32670
37 | BMX2112 | 14039.m00115 | 3.2232184 | 1.688501946362671 | BMX2112 | 14039.m00115 | 3.655596 | 1.870106639049636 | 60S ribosomal protein L3, putative | 14039.m00115 | Bm1_13895 | CE36997
38 | BMX12715 | WB-contig_537 | 3.4095306 | 1.769573132895731 | BMX12715 | WB-contig_537 | 4.2743583 | 2.095707847625033 | 60S ribosomal protein L5, putative | 14961.m04902 | Bm1_32050 | CE02255
39 | bm.00387 | BMC01461 | 3.4225252 | 1.775061164063507 | bm.00408 | BMC01549 | 8.979973 | 3.166711107235391 | Asparaginyl-tRNA synthetase, cytoplasmic, putative | 14971.m02889 | Bm1_36235 | CE28801
40 | BMX11229 | BMW00043.108 | 3.4299245 | 1.778176819933248 | BMX11229 | BMW00043.108 | 2.6749399 | 1.419506477702198 | Asparaginyl-tRNA synthetase, cytoplasmic, putative | 14971.m02889 | Bm1_36235 | CE28801
41 | bm.01075 | BMC04437 | 3.5280037 | 1.818852073925154 | bm.01075 | BMC04437 | 3.6632106 | 1.873108644765206 | beta-tubulin, identical | 14773.m00919 | Bm1_25780 | CE33987
42 | BMX13131 | TC3133 | 3.6210487 | 1.856407579955771 | BMX13131 | TC3133 | 4.7859507 | 2.258805535774898 | heat shock protein 90, putative | 14992.m11078 | Bm1_51495 | CE39622
43 | [NAME] | AA588908 | 3.8627613 | 1.949632528735704 | [NAME] | AA588908 | 3.9359536 | 1.976713213196342 | Translationally controlled tumor protein, putative | 14955.m00256 | Bm1_31480 | CE09656
44 | bm.03280 | BMC03443 | 3.8654306 | 1.950629135982422 | bm.03280 | BMC03443 | 5.6437626 | 2.496657303490457 | Gln-rich protein [Onchocerca volvulus] | BMC03443
45 | bm.01681 | BMC11704 | 3.8823528 | 1.956931225646475 | BMX9336 | AA109462 | 2.0310597 | 1.022232646147169 | FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 | 15451.m00017 | Bm1_56870 | CE05813
46 | BMX1282 | 13390.m00017 | 3.9251492 | 1.972747493751801 | BMX1282 | 13390.m00017 | 3.59686 | 1.846738006780371 | hypothetical protein | 13390.m00017 | Bm1_08470
47 | BMX374 | 12698.m00330 | 3.9661977 | 1.987756592266931 | BMX374 | 12698.m00330 | 2.6913435 | 1.428326535950578 | histone H4, putative | 12698.m00330 | Bm1_02515 | CE16699
48 | [NAME] | AA280466 | 4.0042243 | 2.001522790216423 | [NAME] | AA280466 | 3.8879805 | 1.959020983186532 | unknown | AA280466
49 | bm.01123 | BMC04968 | 4.0478196 | 2.017144994581416 | bm.01123 | BMC04968 | 2.666246 | 1.414809896183478 | NAC domain containing protein | 13260.m00100 | Bm1_06630 | CE33239
50 | BMX11347 | BMW00248.43 | 4.0809703 | 2.028912211159936 | BMX11347 | BMW00248.43 | 3.4270227 | 1.77695574804879 | Asparaginyl-tRNA synthetase, cytoplasmic, putative | 14971.m02889 | Bm1_36235 | CE28801
51 | BMX12914 | TC2909 | 4.0986247 | 2.035139892330012 | BMX9325 | AA089376 | 3.126094 | 1.644361160069795 | 26S proteasome non-ATPase regulatory subunit 7, putative | 14971.m02852 | Bm1_36060 | CE18135
52 | bm.01941 | BMC02223 | 4.310169 | 2.107744437918061 | [NAME] | BMC07116 | 3.2250597 | 1.689325866922483 | Ubiquitin-conjugating enzyme family protein | 14990.m08098 | Bm1_49860 | CE37602
53 | bm.00136 | BMC00330 | 4.327384 | 2.1134951471788 | [NAME] | BMC12295 | 4.6867447 | 2.228586209351722 | [NAME] amylase, catalytic domain containing protein | 12556.m00067 | Bm1_01300 | CE15694
54 | BMX12705 | WB-contig_526 | 4.409478 | 2.14060787769089 | BMX12705 | WB-contig_526 | 6.4224873 | 2.68313213230474 | RNA recognition motif containing protein, putative | 14954.m01718 | Bm1_31255 | CE38662
55 | [NAME] | 12791.m00116 | 4.526055 | 2.178254116143721 | [NAME] | 12791.m00116 | 2.2462587 | 1.16752409145811 | conserved hypothetical protein | 12791.m00116 | Bm1_03160
56 | bm.03498 | BMC12312 | 4.6136827 | 2.205918787966001 | bm.03498 | BMC12312 | 2.780346 | 1.475264430223284 | 60S ribosomal protein L4, putative | 14058.m00567 | Bm1_14285 | CE07669
57 | BMX11919 | WB-contig_1039 | 4.8039603 | 2.264224228639346 | BMX11919 | WB-contig_1039 | 2.9016492 | 1.536873112784437 | Casein kinase II, alpha chain, putative | 14990.m08092 | Bm1_49830 | CE31696
58 | BMX9213 | 15533.m00023 | 4.8068953 | 2.265105380173167 | BMX9213 | 15533.m00023 | 3.3276544 | 1.734505607368269 | hypothetical protein | 15533.m00023 | Bm1_57465
59 | BMX12550 | WB-contig_300 | 4.8740325 | 2.285115870969441 | BMX12550 | WB-contig_300 | 4.1872334 | 2.065997337385046 | Asparaginyl-tRNA synthetase, cytoplasmic, putative | 14971.m02889 | Bm1_36235 | CE28801
60 | bm.02181 | BMC07717 | 5.4835486 | 2.455109814854354 | bm.02181 | BMC07717 | 7.857883 | 2.974140686939331 | Endoplasmin precursor, putative | 14972.m07646 | Bm1_39715 | CE39622
61 | bm.03284 | BMC03611 | 6.004267 | 2.585988132689979 | bm.03284 | BMC03611 | 4.618407 | 2.20739531711554 | calreticulin precursor, putative | 14677.m00169 | Bm1_23560 | CE00423
62 | [NAME] | BMC12461 | 6.753743 | 2.755687281554463 | [NAME] | BMC12461 | 6.760903 | 2.757215948670009 | calreticulin precursor, putative | 14677.m00169 | Bm1_23560 | CE00423
63 | BMX11176 | BMB_gene_5.350 | 6.795596 | 2.764600086465419 | BMX11176 | BMB_gene_5.350 | 8.09005 | 3.016148619160708 | Asparaginyl-tRNA synthetase, cytoplasmic, putative | 14971.m02889 | Bm1_36235 | CE28801
64 | BMX10360 | AW042023 | 6.995991 | 2.806528433304202 | BMX10360 | AW042023 | 5.3072286 | 2.407958691765064 | enolase [Onchocerca volvulus] | AW042023
65 | bm.00336 | BMC01154 | 7.892165 | 2.980421118528952 | bm.00336 | BMC01154 | 2.0567956 | 1.040398429002133 | Gln-rich protein [Onchocerca volvulus] | BMC01154