Spreadsheet: 79f58308-9104-4aac-9f73-a3e5c399e765
Sheet: Sheet1

Table S1 | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14 | Unnamed: 15 | Unnamed: 16 | Unnamed: 17 | Unnamed: 18 | Unnamed: 19 | Unnamed: 20
Function |  |  | Gene |  | Fold changes |  |  |  |  | Mean expressions |  |  |  |  |  |  |  |  |  | p values
 |  |  |  |  | N2 | ire-1 | xbp-1 | pek-1 | atf-6 | N2 |  | ire-1 |  | xbp-1 |  | pek-1 |  | atf-6
 |  |  |  |  |  |  |  |  |  | - | + | - | + | - | + | - | + | - | +
Secretory pathway  (56) | protein folding | chaperone | DNJ-27 |  | 2.191147067163647 | -0.6361791703136168 | -0.363018158871677 | 1.768490671837866 | 2.184350305977308 | 7.416931111356127 | 9.608078178519774 | 7.25809094469119 | 6.621911774377574 | 7.616999611179303 | 7.253981452307626 | 7.693364502160883 | 9.46185517399875 | 7.132778561763903 | 9.31712886774121 | 3.204e-09
 |  |  | DNJ-7, P58IPK |  | 2.116399278422082 | -0.3464078700514692 | -0.5045479728365754 | 1.884910862502297 | 1.586429775968317 | 7.918110801934417 | 10.0345100803565 | 7.422775406505913 | 7.076367536454444 | 7.10220472284765 | 6.597656750011074 | 8.017541616466486 | 9.902452478968783 | 7.854308371830233 | 9.44073814779855 | 6.44e-11
 |  |  | DNJ-28 |  | 1.025662278220544 | -0.09625400013867225 | -0.0917632344407382 | 1.265693880008226 | 0.9948124510845631 | 4.430644353290194 | 5.456306631510738 | 4.389470048048566 | 4.293216047909894 | 4.388429750209474 | 4.296666515768735 | 4.567291892167553 | 5.832985772175779 | 4.554933589623907 | 5.54974604070847 | 7.086e-08
 |  |  | HSP-4* |  | 3.722054726678779 | 0.3115212838850745 | -0.5024187884746372 | 3.093162554606613 | 2.611763280840067 | 9.842452439709554 | 13.56450716638833 | 8.51130706085282 | 8.822828344737895 | 8.864444347557047 | 8.36202555908241 | 10.43448073815565 | 13.52764329276227 | 10.90169132924193 | 13.513454610082 | 7.58e-13
 |  |  | HSP-3* |  | 1.229599138672897 | -0.9622753659530332 | -0.750001346057557 | 1.205467633132699 | 1.2720475162045 | 11.80914425399177 | 13.03874339266467 | 11.44156393228537 | 10.47928856633233 | 10.10647553543973 | 9.356474189382176 | 11.80648719114763 | 13.01195482428033 | 11.43839903778937 | 12.71044655399387 | 3.448e-08
 |  |  | Hsp70 (STC-1, F54C9.2) * |  | 1.830525473961512 | 0.7264881620008214 | 0.01411817442800789 | 1.78970737076191 | 1.60275628421914 | 8.703004889001422 | 10.53353036296293 | 8.519669865284696 | 9.246158027285517 | 9.027522637162797 | 9.041640811590804 | 8.883724857229323 | 10.67343222799123 | 8.885956297667194 | 10.48871258188633 | 4.555e-07
 |  |  | Hsp70  (T14G8.3) |  | 2.514491396652895 | 0.2289250507408784 | -0.6984957897870707 | 2.192452265113694 | 2.118536690272416 | 8.207709306679538 | 10.72220070333243 | 7.509646082471121 | 7.738571133211999 | 8.154086219055715 | 7.455590429268645 | 8.34101824750604 | 10.53347051261973 | 8.48352973760895 | 10.60206642788137 | 1.289e-09
 |  |  | Hsp70 (T24H7.2) |  | 1.238642156528822 | 0.3287467262533994 | 0.0757660762126573 | 0.74913860193268 | 1.351354225074466 | 8.07739957660767 | 9.316041733136492 | 8.273244561529127 | 8.601991287782527 | 8.712102303320572 | 8.78786837953323 | 8.24200758938572 | 8.9911461913184 | 8.074122756960586 | 9.425476982035052 | 0.000556
 |  |  | ERO-1 |  | 1.944713144384 | 0.1682652704414913 | 0.1382621842000979 | 1.894109820727762 | 1.844964912201467 | 9.266814790293333 | 11.21152793467733 | 9.200457627062255 | 9.368722897503746 | 8.763269438481892 | 8.90153162268199 | 9.315436528878173 | 11.20954634960593 | 9.176469304978667 | 11.02143421718013 | 3.55e-10
 |  |  | ERp19 (Y57A10A.23 ) |  | 1.315601548408798 | -0.7401198673172562 | -1.887871783990507 | 0.9375723451512332 | 1.155256719229399 | 10.68836480063487 | 12.00396634904367 | 10.34606980535153 | 9.605949938034277 | 11.26143523032823 | 9.373563446337725 | 10.86376457705033 | 11.80133692220157 | 11.00957197723107 | 12.16482869646047 | 2.29e-14
 |  | Mannosyltransferase (R12E2.13) |  |  | 1.660894963135153 | 0.4310064624303909 | -0.06121258823169917 | 1.551970608550699 | 1.340668952476534 | 10.07252603191585 | 11.733420995051 | 9.79629864670431 | 10.2273051091347 | 9.973900572657259 | 9.91268798442556 | 10.34654822733893 | 11.89851883588963 | 10.5758998295412 | 11.91656878201773 | 1.64e-10
 |  | glucosidase II beta subunit (ZK1307.8) |  |  | 1.178723006951351 | -0.4007688738915434 | -0.6462797381558634 | 0.5350025487015024 | 0.8638062913875117 | 9.12365101310568 | 10.30237402005703 | 8.567203457341376 | 8.166434583449833 | 9.078542189138778 | 8.432262450982915 | 9.277433563350792 | 9.812436112052294 | 9.544278608846822 | 10.40808490023433 | 1.944e-09
 |  | PDI | C14B9.2 * |  | 1.455068208075502 | -0.6398767613263683 | -0.5664288015130339 | 1.069375402830701 | 1.371976814689598 | 11.38967471603307 | 12.84474292410857 | 11.437354283573 | 10.79747752224663 | 11.59491715005873 | 11.0284883485457 | 11.60920391711143 | 12.67857931994214 | 11.3487263937777 | 12.7207032084673 | 3.57e-11
 |  |  | B0403.4* |  | 1.258324035935768 | -0.7620771384214038 | -0.7652668787131329 | 1.102236617538033 | 1.277256243904167 | 11.95638952698487 | 13.21471356292063 | 11.67441163965834 | 10.91233450123693 | 11.63126685836483 | 10.8659999796517 | 12.05415713428617 | 13.1563937518242 | 11.9756077091983 | 13.25286395310247 | 1.66e-12
 |  |  | PDI-2* |  | 1.007138589058167 | -0.7822352328510007 | -1.247990137303832 | 0.8139606602543665 | 0.8420230699604989 | 12.27559599511913 | 13.2827345841773 | 12.23298053039443 | 11.45074529754343 | 11.94513111918793 | 10.6971409818841 | 12.32297155244557 | 13.13693221269993 | 12.3289831106096 | 13.1710061805701 | 1.36e-12
 |  |  | PDI-1 |  | 1.074116282683434 | 0.02598989683366426 | -0.4274707753321003 | 0.9962898792425001 | 1.058514465121968 | 11.790429508975 | 12.86454579165843 | 11.61152923212077 | 11.63751912895443 | 11.7804536251423 | 11.3529828498102 | 11.85517321774603 | 12.85146309698853 | 11.7151146629802 | 12.77362912810217 | 1.553e-09
 |  | signal peptidase | Y54E10BR.5 |  | 1.610166041653045 | -0.3419377060498547 | -0.6891789681187905 | 1.442646818529719 | 1.177079679489033 | 10.05838323906656 | 11.6685492807196 | 9.464490119774313 | 9.122552413724458 | 10.14577133135297 | 9.456592363234176 | 10.03159446788095 | 11.47424128641067 | 10.4101922055999 | 11.58727188508893 | 7.96e-10
 |  |  | C34B2.10 * |  | 1.624537552767235 | 0.00883281323120677 | -0.6576846955262656 | 1.491076080977901 | 1.2304794089157 | 10.5546853324842 | 12.17922288525143 | 10.11216093824126 | 10.12099375147247 | 10.84147335314197 | 10.1837886576157 | 10.54900470863427 | 12.04008078961217 | 10.92607858652067 | 12.15655799543637 | 1.57e-12
 |  |  | Y37D8A.10 * |  | 1.35224239783558 | -0.04718037993140456 | -0.3308031173073971 | 1.32705012778643 | 1.236184714937734 | 10.04201623324892 | 11.3942586310845 | 9.32855304254875 | 9.281372662617345 | 10.12544230527787 | 9.79463918797047 | 10.05202355555317 | 11.3790736833396 | 10.4108343440018 | 11.64701905893953 | 4.393e-08
 |  |  | T05E11.5 * |  | 1.434506987146168 | -0.251788979780768 | -0.3392883236201349 | 1.177836377484098 | 1.315908162096701 | 10.7341833664824 | 12.16869035362857 | 10.66012364559067 | 10.4083346658099 | 10.76180012813773 | 10.4225118045176 | 10.70912032607757 | 11.88695670356167 | 10.5424322082128 | 11.8583403703095 | 4.877e-09
 |  |  | K12H4.4 * |  | 1.226618282283333 | 0.2519834433200998 | -0.5046007107476562 | 1.151527958829668 | 0.9834630284916646 | 10.50312620775233 | 11.72974449003567 | 10.2073367130421 | 10.4593201563622 | 10.52169746477107 | 10.01709675402341 | 10.63235596794867 | 11.78388392677834 | 10.54190825475783 | 11.5253712832495 | 1.216e-09
 | Quality control & ERAD | SEL-1 |  |  | 1.650576142769914 | -0.0684694477445813 | -0.07302921855509048 | 1.055407517972339 | 1.462248113608158 | 9.59161101696502 | 11.24218715973493 | 9.481803642608744 | 9.413334194864163 | 9.259775798241376 | 9.186746579686286 | 9.665335518794793 | 10.72074303676713 | 9.483804959592677 | 10.94605307320083 | 1.011e-09
 |  | P97 protein  (C41C4.8) * |  |  | 1.064179887269768 | -0.7343345124178597 | -1.229122779374313 | 1.269766592364265 | 0.7954897438646675 | 10.50813516275357 | 11.57231505002333 | 10.116234562564 | 9.381900050146138 | 10.25568011034117 | 9.026557330966854 | 10.43320835813983 | 11.7029749505041 | 10.71832482788433 | 11.513814571749 | 2.76e-11
 |  | NSF-1 * |  |  | 1.297440204989501 | -0.2831741045835994 | 0.1041871310439024 | 1.040973966151633 | 1.410162097019768 | 10.3218459729526 | 11.6192861779421 | 10.5308167926799 | 10.2476426880963 | 10.1177218999234 | 10.2219090309673 | 10.31816064614947 | 11.3591346123011 | 10.03503675959007 | 11.44519885660983 | 3.509e-09
 |  | [NAME] like |  | R151.6 | 1.471718302245629 | 0.6751345414689336 | 0.147522646380926 | 1.166987166450699 | 1.294903682344199 | 9.26271088560397 | 10.7344291878496 | 9.215880849841144 | 9.891015391310077 | 9.286340582139195 | 9.43386322852012 | 9.337605692367466 | 10.50459285881817 | 9.3570714692855 | 10.6519751516297 | 9.125e-07
 |  |  |  | F25D7.1 | 2.361376410838201 | 0.3276081462885827 | -0.03380846346136046 | 2.116610534762035 | 1.963500372695556 | 9.765932993612166 | 12.12730940445037 | 9.503950005588218 | 9.8315581518768 | 9.71944688005162 | 9.68563841659026 | 9.931071653419567 | 12.0476821881816 | 10.07245055441231 | 12.03595092710787 | 8.6e-13
 |  | EDEM-1 (C47E12.3) |  |  | 1.317282996724247 | 0.064239669915656 | -0.530875941186876 | 1.148829433263218 | 1.017059758333097 | 9.498092665279486 | 10.81537566200373 | 9.167903544845238 | 9.232143214760894 | 9.995987936174776 | 9.4651119949879 | 9.555757230676981 | 10.7045866639402 | 10.09448438286513 | 11.11154414119823 | 4.985e-08
 |  | HRD1  (F55A11.3) |  |  | 1.19 | 0.3833516028882968 | -0.1172803954895905 | 1.323381728175947 | 1.072017856772739 | 9.549625364638517 | 10.74311861440087 | 9.57323994338327 | 9.956591546271566 | 9.472633421303415 | 9.355353025813825 | 9.562259933738884 | 10.88564166191483 | 9.696818946703763 | 10.7688368034765 | 9.27e-10
 |  | ERD-2 |  |  | 1.055339752986965 | -0.5846154986412309 | -0.9640071787815341 | 0.7523073641018332 | 0.9310362721792682 | 11.2003570601255 | 12.25569681311246 | 11.08455161058026 | 10.49993611193903 | 11.06973723522863 | 10.1057300564471 | 11.34409851532957 | 12.0964058794314 | 11.0076412417277 | 11.93867751390697 | 1.036e-09
 |  | ER retention protein Rer1 (F46C5.8) |  |  | 1.268373886306099 | 0.2826219485428005 | -0.5204468516520837 | 0.9420818010150338 | 0.7907763330082656 | 10.6172550228006 | 11.8856289091067 | 10.37861705803967 | 10.66123900658247 | 10.75095511224543 | 10.23050826059335 | 10.7302756827256 | 11.67235748374063 | 10.94374236424243 | 11.7345186972507 | 1.93e-09
 | ubiquitination | UBX domain containing protein (ZK353.8) |  |  | 1.658687474129202 | 0.4389328569014648 | -0.0716403843806166 | 1.755009129238745 | 1.446452927932869 | 9.9131023653009 | 11.5717898394301 | 9.688270766391602 | 10.12720362329307 | 9.562452311725037 | 9.49081192734442 | 10.00967886338895 | 11.7646879926277 | 10.05402236724306 | 11.50047529517593 | 4.269e-09
 |  | UBA/TS-N domain containing protein (H40L08.1) |  |  | 1.562423920618631 | 0.4978338721402125 | -0.03646863735730754 | 1.345405130876317 | 1.32693235104883 | 8.413991679375206 | 9.976415599993837 | 8.304131806817546 | 8.801965678957758 | 8.330623069098491 | 8.294154431741184 | 8.527697556145936 | 9.873102687022254 | 8.457150544883717 | 9.784082895932547 | 1.227e-08
 |  | UBC-13 |  |  | 1.575926392444254 | 0.06088019101536624 | -0.02046051791518799 | 1.388001707274141 | 1.199850934472357 | 9.61053309191881 | 11.18645948436306 | 9.421522158973577 | 9.482402349988943 | 8.807902652534963 | 8.787442134619775 | 9.801212498822894 | 11.18921420609703 | 9.255221591892743 | 10.4550725263651 | 1.641e-08
 | prot trafficking | ARF & interacting proteins | Arfaptin 1 (F54C8.7) |  | 2.611890086026644 | 0.4773928698423404 | 0.5820901778256236 | 2.06189406748614 | 2.448262291148966 | 9.072188411114087 | 11.68407849714073 | 9.58325526231891 | 10.06064813216125 | 9.240062105538646 | 9.82215228336427 | 9.281103028417027 | 11.34299709590317 | 9.089005098766433 | 11.5372673899154 | 3.23e-13
 |  |  | ARL-6 interacting protein 2 (Y54G2A.2) |  | 1.398889053345069 | 0.460851022172962 | -0.370230282835653 | 0.9276734481787461 | 1.381444600097835 | 8.671416356482164 | 10.07030540982723 | 8.387611362616404 | 8.848462384789366 | 8.447544776666248 | 8.077314493830595 | 8.786023201272707 | 9.713696649451453 | 8.795700324184267 | 10.1771449242821 | 3.479e-08
 |  |  | ARF1-directed GAP (K02B12.7) |  | 1.474131621772152 | 0.5168386869878141 | 0.1859239843755862 | 1.299476959075619 | 1.500091093707097 | 8.52890190834106 | 10.00303353011321 | 8.88520978693706 | 9.402048473924873 | 9.05511669396463 | 9.241040678340216 | 8.7293783257114 | 10.02885528478702 | 8.72368814142317 | 10.22377923513027 | 1.2e-05
 |  |  | ARF GAP 3 (F07F6.4) |  | 1.044985677760968 | 0.1842441798415013 | 0.002646297523568819 | 0.8498941356400334 | 0.7628855788647648 | 10.53704982979277 | 11.58203550755373 | 10.3982198744221 | 10.5824640542636 | 10.85690743706643 | 10.85955373459 | 10.586601633758 | 11.43649576939803 | 10.7643465251785 | 11.52723210404327 | 1.347e-08
 |  |  | GEF for ARF family (Y6B3A.1)* |  | 1.028589595977742 | 0.1768293185404026 | 0.03012248701328701 | 0.7925154318938628 | 0.8586346871700083 | 8.387273145398645 | 9.415862741376387 | 8.458747009373154 | 8.635576327913556 | 8.614686869375287 | 8.644809356388574 | 8.44844202368321 | 9.240957455577073 | 8.541983045388365 | 9.400617732558374 | 5.957e-06
 |  |  | ARL-7 (pseudo gene) |  | 3.371918929405997 | 2.596710716658035 | 1.682630841392635 | 1.854081650652786 | 3.848389954955645 | 7.124713951258837 | 10.49663288066483 | 7.871754692081599 | 10.46846540873963 | 8.15063353901251 | 9.833264380405145 | 6.888817840107127 | 8.742899490759912 | 7.252990371304922 | 11.10138032626057 | 5.309e-09
 |  |  | [NAME] |  | 4.15373924102013 | 2.71884396123838 | 1.441212178897693 | 1.873796462603807 | 4.414587229616184 | 6.065206146144536 | 10.21894538716467 | 6.81281907532671 | 9.53166303656509 | 6.810965715900327 | 8.25217789479802 | 6.181853343883764 | 8.05564980648757 | 6.470048084945417 | 10.8846353145616 | 1.89e-10
 |  | COPI-coated vesicle |  | Coatomer β subunit (Y41C4A.11) | 4.939286187797124 | 1.139569044502105 | 0.3218111495702001 | 2.726816899815649 | 5.301818396302106 | 7.767659009017643 | 12.70694519681477 | 9.060223306990586 | 10.19979235149269 | 7.5536122186525 | 7.8754233682227 | 8.990536052081884 | 11.71735295189753 | 7.788619391476927 | 13.09043778777903 | 1.662e-09
 |  | COPII-coated vesicle | Y105E8A.2 |  | 2.057201706800443 | -0.1277897616531538 | -0.2353155354601677 | 1.897430855588651 | 1.730968820574672 | 8.165155223681458 | 10.2223569304819 | 8.113851345483877 | 7.986061583830723 | 7.910203434139578 | 7.67488789867941 | 8.320119330751684 | 10.21755018634033 | 8.217320042709362 | 9.948288863284034 | 3.63e-10
 |  |  | F41C3.4 * |  | 1.555781426339045 | 0.6986340976092009 | 0.2568173615193405 | 1.46364281470823 | 1.340429073618717 | 8.99533107273052 | 10.55111249906957 | 8.98929590550294 | 9.687930003112141 | 9.22267516942797 | 9.47949253094731 | 9.056993621919004 | 10.52063643662723 | 8.896014609853083 | 10.2364436834718 | 1.058e-06
 |  |  | K08E4.6 |  | 1.432434212563621 | -0.3063278436593802 | -0.6166721545546547 | 1.182853208456752 | 1.230250471744153 | 8.934888908192413 | 10.36732312075603 | 8.646979844321924 | 8.340652000662544 | 9.07231264854627 | 8.455640493991615 | 9.161828921477847 | 10.3446821299346 | 9.135266253550814 | 10.36551672529497 | 8.063e-08
 |  |  | ERGIC-53 (K07A1.8) |  | 1.454581957914233 | 0.06175988061546711 | -0.5512624217459159 | 1.429528010179467 | 1.104186305458001 | 10.49555740283373 | 11.95013936074797 | 10.30398198076797 | 10.36574186138343 | 10.80607416680567 | 10.25481174505975 | 10.58499706455683 | 12.0145250747363 | 10.8354046926884 | 11.9395909981464 | 2.481e-09
 |  |  | SEC-23 * |  | 1.112205298761298 | 0.004224199544065499 | -0.4178475077827013 | 0.9598203302343009 | 0.831645434155865 | 10.89880016651683 | 12.01100546527813 | 11.00376742835713 | 11.0079916279012 | 11.17763758908 | 10.7597900812973 | 11.0352858199573 | 11.9951061501916 | 11.24820211911897 | 12.07984755327483 | 2.993e-06
 |  |  | sec31 like (T01G1.3) |  | 1.159042588123789 | 0.1633756034791034 | 0.2935409058334404 | 0.7344298793925095 | 0.9889704978120832 | 8.435287607908842 | 9.594330196032631 | 8.118251835979322 | 8.281627439458425 | 9.108913912324114 | 9.402454818157555 | 8.441085640199686 | 9.175515519592196 | 8.866603352870353 | 9.855573850682436 | 0.001047
 |  | Clathrin vesicle coat | R07E5.7 * |  | 1.270906713463168 | 0.6090052118857692 | 0.3104669772228998 | 1.2467827224442 | 1.244980679214333 | 10.4801166144583 | 11.75102332792147 | 10.25599841171457 | 10.86500362360034 | 10.5724662649616 | 10.8829332421845 | 10.44122452918357 | 11.68800725162777 | 10.52521178494383 | 11.77019246415817 | 8.538e-07
 |  |  | APM-1* |  | 1.182504402516427 | 0.5944693588830834 | 0.5435251133496326 | 0.8972205254529086 | 1.336969965608667 | 8.485121968037433 | 9.66762637055386 | 8.72618579737383 | 9.320655156256914 | 8.473461716608007 | 9.01698682995764 | 8.665504890909402 | 9.56272541636231 | 8.290198411050786 | 9.627168376659453 | 0.000138
 |  |  | F59E10.3 * |  | 1.095630532293965 | 0.1663576671968006 | 0.5425835422814664 | 1.127594527320035 | 1.028897388306397 | 11.36806466216557 | 12.46369519445953 | 11.51166301533823 | 11.67802068253503 | 11.45074252404263 | 11.9933260663241 | 11.34004521677623 | 12.46763974409627 | 11.5604788856217 | 12.5893762739281 | 4.651e-09
 |  | Vesicle docking | Sec22 (M03E7.5)* |  | 2.102389761377888 | 0.5621372698825393 | 0.5594854507486273 | 1.669964292232177 | 2.227755752811751 | 7.258242685567974 | 9.360632446945862 | 7.386745870420664 | 7.948883140303203 | 7.502814070757487 | 8.062299521506114 | 7.513382248945587 | 9.183346541177764 | 7.430890111215383 | 9.658645864027134 | 3.153e-09
 |  |  | Sec22b (F55A4.1) |  | 1.730447875216562 | 0.4939025803827359 | 0.01542149019191363 | 1.474222403820804 | 1.618499683541238 | 9.103754878793838 | 10.8342027540104 | 9.032021637225768 | 9.525924217608503 | 9.317664459897967 | 9.333085950089881 | 9.014112209926031 | 10.48833461374683 | 9.07154269917933 | 10.69004238272057 | 2.136e-07
 |  |  | Golgi Snare protein (B0272.2 ) |  | 1.627668149778121 | 0.2570583932234314 | -0.1098007461803858 | 1.599185397774531 | 1.350938420853742 | 7.86253758205365 | 9.490205731831772 | 7.709333507884433 | 7.966391901107865 | 7.732990865774906 | 7.62319011959452 | 7.80540044974341 | 9.404585847517941 | 8.00493751267802 | 9.355875933531761 | 4.38e-10
 |  |  | [NAME]* |  | 1.430794534465436 | 0.2045130592080344 | -0.02050331718231213 | 1.265353797349796 | 1.25331511369048 | 8.740834384527098 | 10.17162891899253 | 8.485908484527076 | 8.69042154373511 | 8.556364891618967 | 8.535861574436655 | 8.88004624737728 | 10.14540004472708 | 8.469287831337374 | 9.722602945027853 | 2.085e-08
 |  |  | Integrin (F18H3.4) |  | 1.513023280058361 | 0.3902470029212015 | 0.6022297646039858 | 1.732317072296418 | 1.626773941002714 | 8.330123948626607 | 9.843147228684968 | 8.623677316855824 | 9.013924319777026 | 7.799370038784335 | 8.40159980338832 | 8.377617161307406 | 10.10993423360382 | 8.120064914922603 | 9.746838855925317 | 4.645e-07
 |  |  | alpha-Snap protein (D1014.3)* |  | 1.222813690358032 | 0.4345664219008665 | 0.752685164544717 | 0.9461529682114662 | 1.289625379252236 | 10.7724800383117 | 11.99529372866973 | 11.14049978406067 | 11.57506620596153 | 10.83638553487043 | 11.58907069941515 | 10.79711722714067 | 11.74327019535213 | 10.7603977348707 | 12.05002311412293 | 0.000418
Oxidative stress (5) | Glutathione S-transferases (K01D12.11) |  |  |  | 2.01669970782382 | -0.1936620585812001 | -0.6075712275838168 | 1.801446993105733 | 2.114127095307699 | 10.11516217229781 | 12.13186188012163 | 11.06851403457003 | 10.87485197598883 | 10.71551496096197 | 10.10794373337815 | 10.30547700736273 | 12.10692400046847 | 10.21923888747217 | 12.33336598277987 | 1.595e-07
 | GST-1 |  |  |  | 1.034339094046867 | -0.2969901214966981 | -0.333764452853833 | 1.566350407428835 | 0.5712630193785628 | 11.09307029985437 | 12.12740939390123 | 10.96653056910637 | 10.66954044760967 | 11.42714956984813 | 11.0933851169943 | 11.1325495847884 | 12.69889999221724 | 11.67000508821403 | 12.2412681075926 | 2.117e-09
 | [NAME] (Y76B12C.3) |  |  |  | 1.489029460073981 | -0.1578329471599957 | -0.4134183847433306 | 1.193115356873047 | 1.042724186660511 | 8.87765043469492 | 10.3666798947689 | 8.487218208359335 | 8.32938526119934 | 8.697136027521806 | 8.283717642778475 | 8.977527148473053 | 10.1706425053461 | 9.10631317637969 | 10.1490373630402 | 1.32e-10
 | NADH dehydrogenase (Y47D7A.14)* |  |  |  | 1.12418717725668 | -0.4240864881966946 | -0.8066309160723524 | 1.143192566852106 | 0.865498892194358 | 8.569977248155363 | 9.694164425412042 | 8.414972229605384 | 7.99088574140869 | 8.830413838208093 | 8.02378292213574 | 8.618643728727845 | 9.76183629557995 | 8.743682057199766 | 9.609180949394124 | 3.12e-12
 | SOX-2* |  |  |  | 1.081588037354038 | 0.3660081754763258 | -0.2870725129941132 | 0.6084137380434189 | 0.9622379416132141 | 9.354797654216094 | 10.43638569157013 | 9.461257944702231 | 9.827266120178557 | 9.763075549577907 | 9.476003036583794 | 9.45975565772335 | 10.06816939576677 | 9.56348535598192 | 10.52572329759513 | 2.034e-08
Metabolism  (28) | Lipid & phospholipid metabolism | Choline synthesis | Suppressor of choline synthesis (T12D8.5) |  | 1.250639700968007 | 0.1118648993063793 | 2.061833980857656 | 0.667338314774957 | 1.544636722452463 | 8.30096932672695 | 9.551609027694957 | 8.330182987939057 | 8.442047887245437 | 8.267306738841043 | 10.3291407196987 | 8.345556358999566 | 9.012894673774523 | 8.395842329946737 | 9.9404790523992 | 3.3e-05
 |  |  | Choline kinase (B0285.9) |  | 3.553948592796587 | 0.2847878974626274 | 0.1777483824588204 | 2.472658311663734 | 2.462806436448766 | 9.42187517783998 | 12.97582377063657 | 7.833217163163057 | 8.118005060625684 | 7.869577619921023 | 8.047326002379844 | 10.91043811246883 | 13.38309642413257 | 10.36765206839767 | 12.83045850484643 | 7.56e-13
 |  |  | Choline kinase CKB-4 |  | 2.337947274571874 | 0.4750686560461972 | 0.09420164191749869 | 2.510795821675876 | 2.409908889771586 | 8.530876765013291 | 10.86882403958517 | 8.286662421203902 | 8.761731077250099 | 9.158640338124906 | 9.252841980042405 | 8.635349146453757 | 11.14614496812963 | 8.751164249653515 | 11.1610731394251 | 2.76e-11
 |  | Lipid hydrolysis |  | Lipase class 2 (T13B5.5) | 1.582019555751537 | 0.04888157188220266 | -0.1682014734360564 | 2.756285681802283 | 0.8156582249683275 | 6.435521167678229 | 8.017540723429766 | 6.302785699728894 | 6.351667271611096 | 6.327567673083617 | 6.15936619964756 | 6.901146802445752 | 9.657432484248035 | 6.768661381646413 | 7.58431960661474 | 1.463e-09
 |  |  |  | iPLA2  (F47A4.5) | 2.529021957229394 | 0.9378089829994938 | 1.186184869407104 | 2.042719044026956 | 2.706731120454028 | 6.972921796876586 | 9.50194375410598 | 7.614485123471923 | 8.552294106471416 | 6.82521402035482 | 8.011398889761924 | 7.002919456023516 | 9.045638500050472 | 6.475941894340086 | 9.182673014794114 | 1.414e-06
 |  | Fatty-acid beta-oxidation |  | Enoyl-coA hydratase ([NAME]) | 1.06886429583313 | 0.2318357710332295 | 0.2778373336174802 | 0.8805894378699186 | 1.18374538820413 | 8.250479576495264 | 9.319343872328394 | 7.976793973394018 | 8.208629744427247 | 8.24184214321947 | 8.51967947683695 | 8.406742381028904 | 9.287331818898823 | 8.19530480575911 | 9.37905019396324 | 0.000159
 |  | phospholipids / glycerol acyltransferase |  | K07B1.5b * | 1.522171475550593 | 0.8345590848917563 | 0.6829609397024896 | 1.281932221172493 | 1.523146507167397 | 8.70913128930434 | 10.23130276485493 | 8.932371307523518 | 9.766930392415274 | 9.49345513258161 | 10.1764160722841 | 8.70764780651587 | 9.989580027688367 | 8.858184905181803 | 10.3813314123492 | 0.000795
 |  |  |  | [NAME] | 1.003502322902536 | 0.1010580889856314 | 0.3402681541736854 | 1.02324952275367 | 0.7060222910080753 | 8.856228705660618 | 9.859731028563154 | 8.866064204156906 | 8.967122293142538 | 9.30449486930421 | 9.644763023477896 | 8.997604175867613 | 10.02085369862128 | 9.393222524428014 | 10.09924481543609 | 0.000101
 |  |  |  | F55A11.5 | 2.104805552474827 | -0.1664036953480474 | -0.3854917851077024 | 1.637699506670375 | 2.672047446769513 | 5.52013912599159 | 7.624944678466417 | 5.795820297368991 | 5.629416602020943 | 6.669472350654817 | 6.283980565547115 | 5.917399208461092 | 7.555098715131467 | 5.096126125418666 | 7.768173572188179 | 1.3e-05
 |  |  |  | ACL-12 | 1.058644882708021 | 0.6498312294712321 | 0.2704258583868633 | 0.36478898264013 | 0.862448395622966 | 8.815343176916024 | 9.873988059624045 | 8.91504423620554 | 9.564875465676772 | 8.462010535145547 | 8.73243639353241 | 8.785006481764844 | 9.149795464404974 | 8.196005147567368 | 9.058453543190334 | 0.004548
 |  | long-chain-fatty-acid coA ligase |  | F41C3.3 | 1.758926939574327 | 0.8657907131952722 | 0.4490262491889876 | 1.629973806010799 | 1.264201972560871 | 8.67278415881954 | 10.43171109839387 | 8.62267839071676 | 9.488469103912033 | 9.409561491760199 | 9.858587740949186 | 8.711076517658968 | 10.34105032366977 | 9.070924378135997 | 10.33512635069687 | 8.3e-05
 |  |  |  | F37C12.7 | 1.217982322271203 | 0.6710436362109657 | 0.396326233944885 | 1.159558470033433 | 1.508870452994399 | 10.71570338484526 | 11.93368570711647 | 10.888741800215 | 11.55978543642597 | 10.93100431310367 | 11.32733054704855 | 10.6639026963646 | 11.82346116639803 | 10.56295292854237 | 12.07182338153677 | 1.9e-05
 | Sugar modification | Glucosamine-fructose-6-phosphate aminotransferase (F07A11.2)* |  |  | 3.371864109206159 | 0.5046906254301717 | -0.07624110980038878 | 3.091098703525567 | 3.004561210665498 | 8.864004692556474 | 12.23586880176263 | 8.4394281875042 | 8.944118812934372 | 8.728814450764439 | 8.65257334096405 | 9.034589743995065 | 12.12568844752063 | 9.53428299338767 | 12.53884420405317 | 1.64e-13
 |  | UDP-glucose 4-epimerase (C47B2.6) |  |  | 3.579872734588102 | -1.139182602748046 | -0.7046289714249632 | 3.413531792154298 | 2.497277582116112 | 8.895513103652064 | 12.47538583824017 | 8.959889113185326 | 7.82070651043728 | 9.139877129828898 | 8.435248158403935 | 9.317135440553335 | 12.73066723270763 | 9.846937043402221 | 12.34421462551833 | 1.26e-12
 |  | N-oligosaccharyl transferase (T09A5.11)* |  |  | 0.9799550667367996 | -0.3626927801925675 | -0.6439516300490329 | 0.7038233581494993 | 0.6859138793656658 | 11.29292381185493 | 12.27287887859173 | 11.08970112990533 | 10.72700834971277 | 11.48055115262523 | 10.8365995225762 | 11.3535452298801 | 12.0573685880296 | 11.46713658323593 | 12.1530504626016 | 6.93e-09
 |  | GLY-5a |  |  | 1.025497442991533 | 0.08387313569549626 | -0.1505029151708435 | 0.9419792339830462 | 0.5850174985334675 | 9.749687981286302 | 10.77518542427783 | 9.380966140730436 | 9.464839276425932 | 10.15106054311123 | 10.00055762794039 | 9.88526984075582 | 10.82724907473887 | 10.40543885743577 | 10.99045635596923 | 8e-07
 |  | GLY-5b |  |  | 1.169573747539523 | -0.1502346160570234 | -0.08783820671910725 | 1.360766989320285 | 0.7137922452892234 | 6.41821367319899 | 7.587787420738514 | 6.411313542859047 | 6.261078926802024 | 5.474922338158667 | 5.387084131439559 | 6.713438430320044 | 8.074205419640329 | 6.245079957824664 | 6.958872203113887 | 7.1e-05
 |  | mannose-1-phosphate gaunyl transferase |  | [NAME]* | 1.348996632291595 | 0.2544015135160418 | 0.0272320748459105 | 1.101639525740081 | 1.132236876304644 | 9.121849757176038 | 10.47084638946763 | 9.039381317732591 | 9.293782831248633 | 8.976983808262974 | 9.004215883108884 | 9.178784647606053 | 10.28042417334613 | 8.715573998797993 | 9.847810875102637 | 0.000416
 |  |  |  | Y47D9A.1A | 1.333223992474526 | 0.1597998350567629 | -0.01296141667939921 | 1.239010789466066 | 1.110878430215081 | 9.656386584632541 | 10.98961057710707 | 9.77587308952509 | 9.935672924581853 | 9.80522458554996 | 9.79226316887056 | 9.720789791017268 | 10.95980058048333 | 9.846385998210087 | 10.95726442842517 | 4.53e-10
 | Sugar synthesis | Phosphomannomutase (F52B11.2)* |  |  | 2.654670228361113 | -0.07028276684234491 | -0.2765100097820561 | 2.541116894020583 | 1.941968455669855 | 9.04028988691392 | 11.69496011527503 | 8.613852296471618 | 8.543569529629274 | 8.883625070331966 | 8.60711506054991 | 9.156453877459752 | 11.69757077148033 | 9.86099463392708 | 11.80296308959693 | 1.08e-11
 |  | glycosyl hydrolase (F40F9.6A)* |  |  | 1.203804049583733 | -0.2152528292681968 | -0.7538199342709611 | 0.8507704350542991 | 0.7450466459558331 | 10.26662131245437 | 11.4704253620381 | 10.11716261215857 | 9.90190978289037 | 9.827961375276915 | 9.074141441005954 | 10.37051387784067 | 11.22128431289497 | 10.24146324318457 | 10.9865098891404 | 9.682e-09
 |  | GDP-L-fucose synthetase (R01H2.5) |  |  | 1.447721451709848 | -0.6211410915757476 | -0.3855660266780951 | 1.500437991545136 | 1.404021916137816 | 9.751455839817286 | 11.19917729152713 | 9.336349106859187 | 8.715208015283439 | 9.843889541278186 | 9.45832351460009 | 9.696756910923531 | 11.19719490246867 | 9.837508619323449 | 11.24153053546127 | 1.973e-09
 |  | F38E1.9 |  |  | 1.274417827637466 | -0.07062213776146464 | -0.6408749496765331 | 1.155716842066402 | 0.939148730466302 | 10.81834545800527 | 12.09276328564273 | 10.58812846609377 | 10.5175063283323 | 11.22112189347743 | 10.5802469438009 | 10.94267980275227 | 12.09839664481867 | 11.24200197582547 | 12.18115070629177 | 5.73e-12
 |  | acid alpha-glucosidase (F52D1.1) |  |  | 1.199436395346423 | -0.6254544278724126 | -0.9115553224000532 | 0.6753536469361343 | 0.8379355255329344 | 9.591943533249145 | 10.79137992859557 | 9.563625415773776 | 8.938170987901364 | 9.785982790392218 | 8.874427467992165 | 9.743266294449265 | 10.4186199413854 | 10.0921872354968 | 10.93012276102973 | 5.316e-09
 |  | GDP-D-mannose dehydratase (C53B4.7) |  |  | 1.755715638905107 | 0.05403447403537598 | -0.2145370922299534 | 2.127132039201015 | 1.912877855653644 | 9.069505979602326 | 10.82522161850743 | 8.726843112062186 | 8.780877586097562 | 9.075901004486 | 8.861363912256046 | 8.964520735543386 | 11.0916527747444 | 9.065070290865224 | 10.97794814651887 | 1.223e-06
 |  | carbonic anhydrase bca-1 |  |  | 1.12754086403967 | -0.5489614113618391 | -0.8538059947059722 | 1.13937341305861 | 0.9344612063922373 | 8.944916218709674 | 10.07245708274934 | 9.137557638754773 | 8.588596227392934 | 8.870487432153183 | 8.016681437447211 | 9.182784283691356 | 10.32215769674997 | 8.92640147123236 | 9.860862677624597 | 6.79e-11
 | phosphate mobilization |  |  | T13C5.6 | 1.694803759390791 | 0.4478386957800193 | -0.110051368336384 | 1.631896845006326 | 1.436494272201237 | 9.320267378400944 | 11.01507113779173 | 8.822852881091267 | 9.270691576871286 | 9.403357509605778 | 9.293306141269394 | 9.428954823302474 | 11.0608516683088 | 9.92177873844863 | 11.35827301064987 | 1.5e-10
 | Purine metabolism |  | Xanthine dehydrogenase (B0222.9) |  | 1.490224541854998 | -0.2841857490141528 | 0.8863097367630859 | 1.458899659541471 | 1.114690376475766 | 8.28497499711225 | 9.775199538967248 | 7.637904790162996 | 7.353719041148843 | 7.314203539993353 | 8.200513276756439 | 8.394246906745613 | 9.853146566287084 | 8.429227807660444 | 9.54391818413621 | 1.22e-10
Gene expression  (9) | DNA binding |  | Zinc finger protein (Y38F1A.2 ) |  | 1.125857104381915 | 0.1152402994157544 | 0.3003393654460531 | 1.136306098658768 | 1.08480161932372 | 8.074487223958338 | 9.200344328340252 | 8.126203556549099 | 8.241443855964853 | 7.766109239799597 | 8.06644860524565 | 8.088937931349227 | 9.225244030007994 | 8.189609970261117 | 9.274411589584837 | 1.123e-08
 |  |  | CREBh (F57B10.1)* |  | 1.452206642986061 | 0.08357427434933307 | 0.2189689945201057 | 1.053574705384646 | 1.344649472667275 | 9.707937341011972 | 11.16014398399803 | 10.1402962602506 | 10.22387053459993 | 8.790132466118836 | 9.009101460638941 | 9.895801183405254 | 10.9493758887899 | 8.840372647355037 | 10.18502212002231 | 9.9e-05
 | nucleocytoplasmic transport   T06D8.9 |  |  |  | 2.943554777295894 | 0.350623591405089 | -0.007117465876950391 | 2.671560054583106 | 2.563360516661344 | 9.765104837933473 | 12.70865961522937 | 9.74154884461886 | 10.09217243602395 | 9.772138442808815 | 9.765020976931865 | 10.02678055128503 | 12.69834060586813 | 9.97118692495569 | 12.53454744161703 | 1.03e-14
 | RNA binding |  | [NAME] |  | 2.374731047981669 | 0.2690482072295008 | 0.1157494424320102 | 2.041434593425556 | 1.944369495105644 | 9.012317791346463 | 11.38704883932813 | 8.718256661968704 | 8.987304869198205 | 8.258073072140826 | 8.373822514572836 | 9.23583631283291 | 11.27727090625847 | 9.31038187435619 | 11.25475136946183 | 9.84e-12
 |  |  | T07A5.2 |  | 1.079243759327777 | 0.09375537465455341 | -0.3290351501430306 | 0.8646687378700131 | 0.6140806827183001 | 6.788437218810214 | 7.86768097813799 | 6.818075154829226 | 6.91183052948378 | 6.974651212937661 | 6.64561606279463 | 6.902896895547744 | 7.767565633417757 | 7.095150752923483 | 7.709231435641783 | 2.2e-05
 |  |  | R07E5.12 * |  | 1.118356804160967 | 0.416540612786374 | -0.06507543046871511 | 1.019831565552233 | 1.013662472807365 | 10.2696678083134 | 11.38802461247437 | 9.928590244201024 | 10.3451308569874 | 10.31129263405266 | 10.24621720358395 | 10.24599891402253 | 11.26583047957477 | 10.27132666296543 | 11.2849891357728 | 6.773e-08
 | RNA pol |  | RRF-2 |  | 2.460635164861681 | 1.203087253334409 | 0.69092086766649 | 1.958180267925129 | 2.25562304268067 | 7.120006151373061 | 9.580641316234741 | 7.81734923634378 | 9.02043648967819 | 7.10147282948122 | 7.79239369714771 | 7.451000851243253 | 9.409181119168382 | 6.647208102985104 | 8.902831145665774 | 4.213e-07
 |  |  | Rpb7 (Y54E10BR.6)* |  | 1.2502391174956 | 0.1463942419746616 | -0.03848515133509878 | 1.296758134422101 | 1.079279036021367 | 10.46448922255823 | 11.71472834005383 | 9.994242774237039 | 10.1406370162117 | 10.4113536467718 | 10.3728684954367 | 10.4510859039527 | 11.7478440383748 | 10.6828825986687 | 11.76216163469007 | 8.623e-08
 | translation initiation |  |  | NLP-28 | 1.609987247270452 | 0.713329749603691 | 1.5093693384327 | 1.385599596984573 | 0.6362349752014129 | 8.667701570769816 | 10.27768881804027 | 8.327312847771877 | 9.040642597375568 | 8.86860949779865 | 10.37797883623135 | 9.710128899658427 | 11.095728496643 | 9.595886603705287 | 10.2321215789067 | 0.000104
Cell growth & death (5) | Apoptosis |  | BAP31 (Y54G2A.18) |  | 2.717104194871633 | 1.004447659443198 | 0.7013711542548844 | 2.266022486264902 | 2.559594653235399 | 11.16026324252253 | 13.87736743739416 | 10.91997751404157 | 11.92442517348477 | 10.94492132594557 | 11.64629248020045 | 11.46823021936457 | 13.73425270562947 | 11.26776764229093 | 13.82736229552633 | 2.53e-10
 | Mitosis |  | CEP2  (T28C6.7) |  | 1.009478659451108 | -0.2142870864550872 | -0.158729934610351 | 0.9477883033422412 | 0.806056294851393 | 9.562211731628791 | 10.5716903910799 | 9.557851605078037 | 9.34356451862295 | 8.963771071071337 | 8.805041136460986 | 9.606436313127226 | 10.55422461646947 | 9.075757727699889 | 9.881814022551282 | 2.165e-08
 | CDK5 activator-binding protein C53 like  (Y113G7B.16) |  |  |  | 1.839907811541524 | -0.07015516621340989 | -0.2220439188662997 | 1.302918238324892 | 1.368451765497784 | 5.59658138385763 | 7.436489195399154 | 5.552249043901544 | 5.482093877688134 | 5.30827766303814 | 5.086233744171841 | 5.978792274677827 | 7.281710513002719 | 5.853463046781493 | 7.221914812279277 | 5.041e-08
 | Defecation Suppressor of Clk-1 (DSC-4)* |  |  |  | 1.88832472870479 | -0.8659759716942581 | -0.8184846980038483 | 1.624134113665541 | 1.128169850318333 | 9.64628731914081 | 11.5346120478456 | 9.1775373482476 | 8.311561376553342 | 9.479745885978064 | 8.661261187974215 | 9.762518439145394 | 11.38665255281093 | 10.5052707992391 | 11.63344064955743 | 5.19e-12
 | Piwi-domain containing protein (C04F12.1) |  |  |  | 3.262104236598713 | 0.5506477987594742 | 0.2926921660154953 | 3.139557574365929 | 3.368275604253748 | 8.600692363274556 | 11.86279659987327 | 8.166729132956052 | 8.717376931715526 | 8.22849797503817 | 8.521190141053665 | 8.740403731665573 | 11.8799613060315 | 8.424533260020551 | 11.7928088642743 | 2.56e-15
Calcium homeostasis (5) | Nucleobindin (F44A6.1) |  |  |  | 1.037215250581614 | 0.05073706969977643 | -0.8014509267609551 | 0.8882098445791105 | 0.813696114282731 | 9.741870556411085 | 10.7790858069927 | 9.691284165545847 | 9.742021235245623 | 9.82068103430317 | 9.019230107542215 | 9.75776789850019 | 10.6459777430793 | 10.1617823466142 | 10.97547846089693 | 5.527e-08
 | Calumenin   (M03F4.7)* |  |  |  | 1.617238316811502 | -0.8437999953614739 | -0.822997329504501 | 0.9554355852894343 | 1.321635812196135 | 10.9773520975119 | 12.5945904143234 | 11.0395521737966 | 10.19575217843513 | 11.1267425309889 | 10.3037452014844 | 11.2956399780607 | 12.25107556335013 | 11.00430308870707 | 12.3259389009032 | 1.91e-10
 | SCA-1* |  |  |  | 1.076335444364833 | 0.1744137036683338 | -0.220697748766618 | 0.9164770754296327 | 1.025442301450802 | 10.2847594838625 | 11.36109492822733 | 10.2600493156298 | 10.43446301929813 | 10.44205863277607 | 10.22136088400945 | 10.33458231746983 | 11.25105939289947 | 10.30893516656697 | 11.33437746801777 | 5.107e-08
 | UNC-68 |  |  |  | 1.342289316725902 | -0.6670076855359532 | 1.964139206656057e-05 | 1.012512005895765 | 1.141415662488766 | 10.4686277648042 | 11.8109170815301 | 10.558813092452 | 9.891805406916047 | 10.73310418695843 | 10.7331238283505 | 10.54833160656283 | 11.5608436124586 | 10.23825604891537 | 11.37967171140413 | 3.432e-07
 | Herp (F25D7.2) |  |  |  | 1.298271295276962 | 0.2064211380410388 | 0.09053766309740574 | 1.315361689513701 | 1.198408348638301 | 9.611844304059806 | 10.91011559933677 | 9.590936539320941 | 9.79735767736198 | 8.906565751007804 | 8.99710341410521 | 9.620744633436098 | 10.9361063229498 | 9.5298103292808 | 10.7282186779191 | 3.593e-07
[NAME] function (4) | Mitochondrial proteins import receptor (CE16893) |  |  |  | 1.169727837670965 | 0.5207700125742338 | 0.02024252393714399 | 1.130321906679269 | 1.026724399345088 | 8.438064368488371 | 9.607792206159337 | 8.039212158023403 | 8.559982170597637 | 8.941703031970041 | 8.961945555907185 | 8.52103969201903 | 9.6513615986983 | 8.846895600544775 | 9.873619999889863 | 2.4e-05
 | FIS-2 |  |  |  | 1.97501541511868 | 0.8772378696306333 | 0.5223792376204983 | 2.084619833471958 | 2.010739627928118 | 8.555355456908787 | 10.53037087202747 | 8.753884336657764 | 9.631122206288397 | 8.814727178007592 | 9.33710641562809 | 8.494423195444442 | 10.5790430289164 | 8.54201366744728 | 10.5527532953754 | 2.33e-10
 | K12H4.2 |  |  |  | 1.111868904203516 | 0.6677998963974998 | 0.2069163318710041 | 1.110342531484704 | 1.194474669733819 | 6.475290156886697 | 7.587159061090213 | 6.206961989843816 | 6.874761886241316 | 6.51023907781792 | 6.717155409688925 | 6.469519652599899 | 7.579862184084604 | 6.573028882624527 | 7.767503552358346 | 5.054e-06
 | Lon protease (C34B2.6) |  |  |  | 1.16649897467897 | 0.2217247293633511 | -0.5705951284344222 | 1.056280231580343 | 0.885895482433769 | 7.566994519586513 | 8.733493494265483 | 7.030348631512396 | 7.252073360875747 | 7.996617951931417 | 7.426022823496995 | 7.68616221000362 | 8.742442441583963 | 7.814277810233264 | 8.700173292667033 | 2.46e-06
Signal transduction (6) | G protein & coupled receptoers |  |  | F28H7.6 | 2.168830843162394 | 0.46973640170979 | 0.40819115213956 | 2.105954970605008 | 1.871443147248335 | 6.197629936933169 | 8.366460780095563 | 6.580566632646334 | 7.050303034356124 | 6.23907215189064 | 6.6472633040302 | 6.2258498156009 | 8.331804786205907 | 6.283905846834891 | 8.155348994083226 | 3.391e-08
 |  |  |  | ZK265.5 * | 1.926598472268958 | 0.2400886447239881 | -0.4592203722586188 | 1.909162528939351 | 1.69051747624378 | 9.302590623165507 | 11.22918909543447 | 8.658485197580973 | 8.89857384230496 | 9.430101069438914 | 8.970880697180295 | 9.362192934803883 | 11.27135546374323 | 9.60622717134552 | 11.2967446475893 | 8.72e-10
 |  |  |  | F46C5.9 | 1.233520790872946 | -0.05932701146497266 | 0.03110135704779893 | 1.002724136484449 | 1.200780499113032 | 9.214944705972421 | 10.44846549684537 | 9.332509774322503 | 9.27318276285753 | 9.382277006784006 | 9.413378363831805 | 9.303080603339984 | 10.30580473982443 | 9.533823066932568 | 10.7346035660456 | 6e-09
 |  |  |  | K02B12.3 * | 1.209778950893776 | 0.6033547920282185 | 0.3448946038273544 | 0.8532343592617924 | 1.072179306828868 | 9.73646690194599 | 10.94624585283977 | 9.911251758235647 | 10.51460655026387 | 9.846977728418496 | 10.19187233224585 | 9.810664370280874 | 10.66389872954267 | 9.713697507755933 | 10.7858768145848 | 1.2e-05
 |  |  |  | K06C4.8 | 1.12679289660679 | 0.1242011468132809 | 0.882948395535613 | 0.9113184510643482 | 0.8558706285850564 | 6.901143801841124 | 8.027936698447913 | 6.677352190868663 | 6.801553337681944 | 7.092316148516493 | 7.975264544052106 | 7.113245750250353 | 8.024564201314702 | 6.87719666827597 | 7.733067296861027 | 0.001517
 | MAPK12 (DLK-1) |  |  |  | 1.123433856815371 | 0.09742737284596892 | 0.6771574363631849 | 0.96728209431223 | 1.191585160072307 | 9.726346474584627 | 10.8497803314 | 9.858227475126299 | 9.955654847972268 | 10.27615465282646 | 10.95331208918965 | 9.743401984511836 | 10.71068407882407 | 9.79145923534116 | 10.98304439541347 | 5.839e-06
Ion channels & transporters (9) | Voltage-gated potassium channel (F22E5.6) |  |  |  | 3.0491834198494 | 1.431986955375242 | 0.2638591090646214 | 0.6752671918453066 | 3.00374999861418 | 6.134660556500177 | 9.183843976349577 | 6.21952293399812 | 7.651509889373362 | 6.237754025759073 | 6.501613134823694 | 6.089586144354993 | 6.7648533362003 | 6.26143910066956 | 9.26518909928374 | 2.39e-10
 | Voltage-gated potassium channel (ZC239.12) |  |  |  | 2.576265519953927 | 0.9011295804789361 | 0.35601525905287 | 0.5232002631515265 | 3.012885366363392 | 4.558947636934956 | 7.135213156888883 | 4.787261868060583 | 5.68839144853952 | 4.63860176268575 | 4.99461702173862 | 4.546482391605706 | 5.069682654757233 | 4.56030987357082 | 7.573195239934212 | 1.361e-09
 | Cation diffusion facilitator  [NAME] |  |  |  | 1.098578907579372 | -0.1700487728543658 | -1.080014298024826 | 0.3077306722086437 | 0.8470802285897765 | 7.152958119141331 | 8.251537026720703 | 6.750345205185283 | 6.580296432330917 | 8.04584397844145 | 6.965829680416625 | 7.199971868151846 | 7.50770254036049 | 7.525220226043267 | 8.372300454633043 | 1e-05
 | Cation transporter/ATPase (C09H5.2) |  |  |  | 1.585936499339606 | 0.4752066998911939 | 2.528423183151322 | 2.115834990603233 | 2.519307279510404 | 9.014138830927761 | 10.60007533026737 | 9.472546641211629 | 9.947753341102823 | 9.419257568196729 | 11.94768075134805 | 8.8594574600183 | 10.97529245062153 | 8.139700013483763 | 10.65900729299417 | 1.822e-07
 | Divalent cation transporter SMF-1 |  |  |  | 1.28429888859174 | 0.1662325048112834 | 0.285317953740007 | 1.064012465099577 | 1.186823151973869 | 8.434686300625923 | 9.718985189217664 | 8.52422584170003 | 8.690458346511313 | 8.755895307880989 | 9.041213261620996 | 8.458455563407663 | 9.52246802850724 | 8.896886852220092 | 10.08371000419396 | 3.273e-06
 | Copper homeostasis protein (ZK353.7) |  |  |  | 1.073232484783212 | 0.2529090773844658 | -0.07859451358016578 | 1.079420381008694 | 0.7457525331973471 | 8.561719921494296 | 9.634952406277508 | 8.259501338894514 | 8.51241041627898 | 8.534902634964945 | 8.45630812138478 | 8.555589992874546 | 9.63501037388324 | 8.573316737537818 | 9.319069270735165 | 5.9e-05
 | Zinc transporter (T28F3.3) |  |  |  | 3.219866965700538 | 0.08913369897673995 | 0.04153486603793954 | 3.265710850120207 | 2.82037810576529 | 6.59426670686765 | 9.814133672568188 | 6.347461511630537 | 6.436595210607277 | 6.03533590981693 | 6.07687077585487 | 6.605367329725641 | 9.871078179845847 | 6.52110119224783 | 9.34147929801312 | 2.55e-14
 | Oligopeptide transporter (OPT-1) |  |  |  | 1.092528120681699 | -0.1709561741167835 | 0.3310238898809335 | 1.08174242171777 | 1.2341464760215 | 8.330580304743103 | 9.423108425424802 | 8.80463901362547 | 8.633682839508687 | 8.290175397858517 | 8.62119928773945 | 8.44099752449921 | 9.52273994621698 | 8.290603531728443 | 9.524750007749944 | 2.17e-06
 | UDP-galactose transporter (Y111B2A.20) |  |  |  | 1.517944845660026 | -0.2428676281637578 | -0.5564624483678724 | 1.608892726795007 | 1.328850563552564 | 9.342486800594775 | 10.8604316462548 | 8.95253255604055 | 8.709664927876792 | 9.352037435447771 | 8.795574987079899 | 9.38426889015486 | 10.99316161694987 | 9.284901942671338 | 10.6137525062239 | 1.04e-07
others (12) | cytoskeleton |  |  | F09E8.2 | 1.083951867227951 | -0.08648637587266172 | -0.6058614036894809 | 0.8134862276611674 | 1.057740191990764 | 8.537787718016773 | 9.621739585244724 | 8.168186519048444 | 8.081700143175782 | 8.71100822386348 | 8.105146820174 | 8.588317367279522 | 9.40180359494069 | 8.70419865966137 | 9.761938851652134 | 2.13e-10
 |  |  |  | PGN-96 | 1.763368144757674 | 0.8958791162095956 | 0.04493976658869947 | 1.092055921166409 | 1.685747251564552 | 8.353328022223193 | 10.11669616698087 | 8.4116932979879 | 9.307572414197496 | 8.37626812694577 | 8.42120789353447 | 8.65921042980487 | 9.75126635097128 | 8.601433945979949 | 10.2871811975445 | 1.316e-07
 |  |  |  | Y25C1A.4 | 1.851249888367822 | 0.03173933796055994 | -0.06270553082647723 | 1.75518331771205 | 3.914374872492973 | 6.466434202283136 | 8.317684090650959 | 6.376606522765637 | 6.408345860726197 | 6.261458245489957 | 6.19875271466348 | 6.326001941586013 | 8.081185259298064 | 6.510663060909127 | 10.4250379334021 | 3.907e-08
 | cuticle synthesis |  |  | C37A5.8 | 3.431882208364819 | 0.6688755916764721 | 1.38224283612973 | 4.046939957879785 | 2.789199780989081 | 7.57794662027838 | 11.0098288286432 | 7.560963433182576 | 8.229839024859048 | 6.987590883532076 | 8.369833719661806 | 7.963995321243616 | 12.0109352791234 | 7.489753499542119 | 10.2789532805312 | 3.37e-11
 |  |  |  | dyp-18 | 3.032371832762573 | -0.6564690660803407 | -1.450623897875284 | 2.191726350717701 | 2.896835323447922 | 10.07036481519253 | 13.1027366479551 | 10.06246187496413 | 9.405992808883793 | 9.671399787523619 | 8.220775889648335 | 10.903083223213 | 13.0948095739307 | 9.95906094014371 | 12.85589626359163 | 9.27e-14
 |  |  |  | F17C8.2 | 1.52091667859511 | -0.08653031542132972 | -0.2066500400361067 | 1.222760845865166 | 1.724062584670088 | 7.136388334056224 | 8.657305012651333 | 7.374959955042553 | 7.288429639621223 | 7.217118651085937 | 7.010468611049831 | 7.239020909312977 | 8.461781755178142 | 7.683392143154194 | 9.407454727824282 | 4.485e-08
 | host defense |  | C36B7.6 |  | 1.169127185531389 | 0.009057631565044133 | -0.6295889461739144 | 1.045728285601363 | 0.9952034537670738 | 9.021694507684911 | 10.1908216932163 | 8.482053946752586 | 8.49111157831763 | 9.858912247540564 | 9.22932330136665 | 9.067911108008357 | 10.11363939360972 | 9.559751856867626 | 10.5549553106347 | 4.648e-08
 |  |  | Serine protease inhibitor SRP-7 |  | 2.121123999948535 | 0.05832183142416802 | 0.2742660250497639 | 1.965274609064535 | 1.690368599386034 | 11.33766922155537 | 13.4587932215039 | 11.3164564800701 | 11.37477831149427 | 11.20501638859984 | 11.4792824136496 | 11.55941789790607 | 13.5246925069706 | 11.77508836742627 | 13.4654569668123 | 2.26e-13
 | protein interaction | DHHC zinc binding domain (K02G10.1) |  |  | 1.25358168009638 | -0.3463978651693935 | -0.009317321230016162 | 1.291965997996213 | 0.9449912936764786 | 8.483673963865586 | 9.737255643961966 | 9.01144138523757 | 8.665043520068176 | 8.402830254945867 | 8.39351293371585 | 8.74878760979243 | 10.04075360778864 | 8.333797342491616 | 9.278788636168095 | 2.256e-07
 |  | F-box containing proteins |  | D1025.3 | 1.232591243056587 | 0.05315328520246432 | 0.6990518716784342 | 0.9440155181537433 | 1.166615494272404 | 7.222903841515209 | 8.455495084571796 | 7.206601042674106 | 7.25975432787657 | 7.638595036036651 | 8.337646907715085 | 7.17502283245829 | 8.119038350612033 | 7.642382400571976 | 8.80899789484438 | 5.6e-05
 |  |  |  | T12B5.1 | 2.092008932390498 | 0.2045946227813964 | 0.3336952176117762 | 1.736546523400423 | 0.4975557337637904 | 4.836462810024853 | 6.928471742415351 | 4.56480890790105 | 4.769403530682446 | 4.507325438857014 | 4.84102065646879 | 4.88665376939756 | 6.623200292797983 | 4.31805907464042 | 4.81561480840421 | 1.947e-07
 |  |  |  | F36H5.5 | 1.036648874881131 | -0.05966277838730782 | -0.112201012286504 | 1.134677701347039 | 0.3192375806388927 | 6.09015929133422 | 7.12680816621535 | 6.108560159043004 | 6.048897380655696 | 5.961363751414264 | 5.84916273912776 | 5.936173323356537 | 7.070851024703576 | 6.062626334750941 | 6.381863915389833 | 3.532e-06
Unknown (30)