Spreadsheet: 8dc0a095-cad9-48bf-afb6-1ce1b135e996
Sheet: Sheet1

Table S4 - PiPLC shaving identities / iTRAQ ratios | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14 | Unnamed: 15
Category | Accession Number (Schistosoma mansoni databases) |  |  |  |  |  | Protein identity |  |  | 115/114 | 116/114 | 117/114 | SD (geo) | SD (geo) | SD (geo)
 | Clustered ESTs |  |  | Predicted Gene |  |  |  |  |  |  |  |  | 115/114 | 116/114 | 117/114
Membrane
 | Sm09193 |  |  | Smp_072190 |  |  | Sm29 |  |  | 0.616 | 9.565 | 9.883
 | Sm03249 |  |  | Smp_019350 |  |  | CD59a |  |  | 0.866 | 8.706 | 6.115 | 1.195 | 1.526 | 1.446
 |  |  |  | Smp_017730* |  |  | Sm200 |  |  | 0.837 | 7.749 | 5.038 | 1.124 | 1.27 | 1.283
 | Sm04975 |  |  | Smp_168730 |  |  | Carbonic Anhydrase |  |  | 1.04 | 6.803 | 5.121 | 1.148 | 1.526 | 1.66
 | Sm00433 |  |  | Smp_105220 |  |  | CD59b |  |  | 0.793 | 5.092 | 4.384 | 1.105 | 2.108 | 1.881
 |  |  |  | Smp_155890 |  |  | [NAME] |  |  | 0.998 | 2.936 | 3.044 | 1.139 | 1.67 | 2.67
 | Sm01523 |  |  | Smp_025830 |  |  | ADP-ribosyl cyclase (SARC) |  |  | 0.871 | 2.88 | 1.799 | 1.103 | 1.136 | 1.18
 | Sm12366 |  |  | Smp_181530 |  |  | CD63 like tetraspanin TSP-2 |  |  | 1.038 | 0.767 | 0.655
 | Sm04814 |  |  | Smp_074140* |  |  | Annexin type IV |  |  | 0.997 | 0.817 | 0.513
Cytoskeletal
 | Sm00900* |  |  | Smp_046590.2* |  |  | [NAME] |  |  | 1.09 | 0.88 | 0.722 | 1.021 |  | 1.101
 | Sm12742* |  |  | Smp_008660.1* |  |  | Putative Villin |  |  | 0.947 | 0.778 | 0.657 | 1.093 | 1.067 | 1.381
 | Sm00714 |  |  | Smp_032950 |  |  | Cytoplasmatic Dynein Light Chain |  |  | 0.927 | 0.851 | 0.731
 | Sm00101 |  |  | Smp_086530 |  |  | Sm20.8 |  |  | 0.906 | 0.711 | 0.593
 | Sm03938 |  |  | Smp_086480 |  |  | [NAME] |  |  | 1.086 | 0.81 |  | 1.084 | 1.605
Cytosolic enzymes
 | Sm12193 |  |  | Smp_024110 |  |  | Enolase |  |  | 1.008 | 0.674 | 0.569 | 1.095 | 1.073 | 1.12
 | Sm05684 |  |  | Smp_042160.1* |  |  | Frutose Biphosphate Aldolase |  |  | 1.026 | 0.884 | 0.838 | 1.084 | 1.256 | 1.582
 | Sm12777 |  |  | Smp_040130* |  |  | Peptidyl Prolil Cis Trans Isomerase |  |  | 1.161 | 1.024 |  | 1.083 | 1.179
 | Sm06243 |  |  | Smp_83870.2 |  |  | [NAME] |  |  | 1.089 | 0.658 | 0.64
 | Sm12448 |  |  | Smp_059480 |  |  | Thioredoxin Peroxidase 1 |  |  | 0.88 | 0.772 | 0.834
 | Sm01020 |  |  | Smp_059790.1* |  |  | Transketolase |  |  | 0.839 | 0.518 | 0.549 | 1.218 | 1.23 | 1.426
 | Sm12959 |  |  | Smp_092750 |  |  | Nucleoside Diphosphate Kinase |  |  | 0.915 | 0.748 | 0.822 | 1.074 | 1.107 | 1.263
 | Sm00627 |  |  | [NAME] |  |  | Problable Hidroxyacylglutathione Hidrolase |  |  | 1.149 | 0.8 | 0.542
 | Sm02267 |  |  | Smp_054160 |  |  | Glutathione S-transferase 28kDa |  |  | 1.037 | 0.653 | 0.449
 | Sm03515 |  |  | Smp_053220.1* |  |  | Aldo/Keto Reductase |  |  | 0.912 | 0.76 | 0.471
 | Sm11464 |  |  | Smp_142370.1 |  |  | Phosphatidylinositol-4-phosphate-5-kinase Type II Beta |  |  | 1.22 | 1.354 | 1.298
 | Sm03441 |  |  | Smp_096760 |  |  | Phosphoglycerate Mutase |  |  | 0.878 | 0.768 | 0.673
 | Sm00999 |  |  | Smp_003990 |  |  | Triose Phosphate Isomerase |  |  | 0.886 | 0.551 | 0.652 | 1.215 | 1.191 | 1.283
Cytosolic proteins
 | Sm04779 |  |  | Smp_095360* |  |  | Sm14 |  |  | 1.202 | 1.083 | 0.547 | 1.085 | 1.063 | 1.61
 | Sm12452 |  |  | Smp_009760 |  |  | 14.3.3 Protein |  |  | 0.985 | 0.723 | 0.572 | 1.62 | 1.068 | 1.084
 | Sm01524 |  |  | Smp_072330* |  |  | [NAME] |  |  | 1.001 | 1.257 | 1.261 | 1.11 | 1.257 | 1.261
 | Sm09042 |  |  | Smp_182190* |  |  | Hsp70 |  |  | 1.031 | 0.633 | 0.708 | 1.077 | 1.12 | 1.264
 | Sm01636* |  |  | Smp_006390 |  |  | Cysteine Protease Inhibitor |  |  | 1.056 | 0.802 | 0.749
 | Sm12307 |  |  | [NAME] |  |  | Serpin |  |  | 1.196 | 1.081 | 0.837 | 1.146 | 1.41 | 1.217
 |  |  |  | Smp_079230 |  |  | Immunophillin |  |  | 0.972 | 0.528 | 1.201 | 1.218 | 1.609 | 1.562
 | Sm01930 |  |  | Smp_151690 |  |  | Translation Inhibitor [NAME] |  |  | 0.992 | 0.844 | 0.756
 | Sm00127 |  |  | Smp_032580.1* |  |  | Proteassome Subunit |  |  | 0.92 | 1.01 | 1.022
Secreted/Gut
 | Sm02368 |  |  | Smp_053310 |  |  | LMWP |  |  | 1.199 |  |  | 1.048
 |  |  |  | Smp_089670 |  |  | [NAME] Macroglobulin |  |  | 1.016 | 0.853 | 0.665 | 1.068 | 1.061 | 1.086
 | Sm12579 |  |  | Smp_014570 |  |  | Saposin B |  |  | 0.904 | 0.49 | 0.493
Unknowns
 | Sm06535 |  |  | Smp_184180* |  |  | Unknown |  |  | 1.057 | 0.978 | 0.819 | 1.068 | 1.039 | 1.191
 | Sm06918 |  |  | Smp_009230* |  |  | Unknown |  |  | 1.088 | 1.163 | 0.65
 | Accession Number (NCBInr Mus musculus database)
Membrane
 | CAA26549 |  |  |  |  |  | Thy1,2 |  |  | 0.927 | 4.528 | 3.191
 | [NAME] |  |  |  |  |  | CD48 Antigen |  |  | 0.848 | 8.568 | 5.481
Cytoskeletal
 | CAA31455 |  |  |  |  |  | [NAME] |  |  | 1.09 | 0.88 | 0.722 | 1.021 |  | 1.101
Cytosolic enzymes
 | [NAME] |  |  |  |  |  | [NAME] 70 |  |  | 0.928 | 0.557 | 0.377 | 1.012 | 1.249 | 1.032
 | AAA40121 |  |  |  |  |  | Superoxide Dismutase |  |  | 0.879 | 0.59 | 0.611 | 1.108 | 1.233 | 1.12
 | NP_036097 |  |  |  |  |  | Proteasome [NAME] Type 5 |  |  | 0.92 | 1.01 | 1.022
[NAME]
 | [NAME] |  |  |  |  |  | 14-3-3 Zeta |  |  | 0.903 | 0.575 | 0.43
Contaminant
 | CAA24214 |  |  |  |  |  | Keratin |  |  | 1.365 | 1.135 | 0.71
 | BAB31776 |  |  |  |  |  | [NAME] |  |  | 1.104 | 0.933 |  | 1.048 | 1.13
 | [NAME] |  |  |  |  |  | Keratin 76 |  |  | 1.334 | 1.274 | 0.724
 | CAA52788 |  |  |  |  |  | Keratin 2 |  |  | 1.116 | 0.797 | 1.143
* Peptide hits common to more than one predicted protein
[NAME]) = standard geometric deviation (provided for protein identities obtained from at least 3 peptide fragmentations with expect score < 0.05)
Protein identities obtained from fragmentations of 1 and 2 peptides are reported based on their significant  [NAME] expect score (<0.05) in three independent iTRAQ experiments.