Spreadsheet: 79627d71-1282-4565-9d35-2d0cb7a50735
Sheet: Sheet1

Strain\Gene | IGR(fliG-tp0027) | Unnamed: 2 | Unnamed: 3 | cysS | tp0106 | Unnamed: 6 | Unnamed: 7 | tp0123 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | IGR(tp0129-tp0130) | Unnamed: 14 | Unnamed: 15 | IGR(tp0135-tp0136) | Unnamed: 17 | Unnamed: 18 | Unnamed: 19 | Unnamed: 20 | Unnamed: 21 | deoD | Unnamed: 23 | gpd | Unnamed: 25 | tp92 | Unnamed: 27 | Unnamed: 28 | Unnamed: 29 | Unnamed: 30 | Unnamed: 31 | Unnamed: 32 | Unnamed: 33 | Unnamed: 34 | Unnamed: 35 | Unnamed: 36 | Unnamed: 37 | Unnamed: 38 | Unnamed: 39 | Unnamed: 40 | Unnamed: 41 | Unnamed: 42 | Unnamed: 43 | Unnamed: 44 | Unnamed: 45 | Unnamed: 46 | Unnamed: 47 | Unnamed: 48 | Unnamed: 49 | Unnamed: 50 | Unnamed: 51 | Unnamed: 52 | Unnamed: 53 | Unnamed: 54 | Unnamed: 55 | Unnamed: 56 | Unnamed: 57 | Unnamed: 58 | Unnamed: 59 | Unnamed: 60 | Unnamed: 61 | Unnamed: 62 | Unnamed: 63 | Unnamed: 64 | Unnamed: 65 | Unnamed: 66 | Unnamed: 67 | Unnamed: 68 | Unnamed: 69 | Unnamed: 70 | Unnamed: 71 | Unnamed: 72 | Unnamed: 73 | Unnamed: 74 | Unnamed: 75 | Unnamed: 76 | Unnamed: 77 | Unnamed: 78 | Unnamed: 79 | Unnamed: 80 | Unnamed: 81 | Unnamed: 82 | Unnamed: 83 | Unnamed: 84 | Unnamed: 85 | Unnamed: 86 | tp0347 | Unnamed: 88 | Unnamed: 89 | Unnamed: 90 | Unnamed: 91 | Unnamed: 92 | IGR(cheY-tp0367) | Unnamed: 94 | Unnamed: 95 | Unnamed: 96 | Unnamed: 97 | rpiA | Unnamed: 99 | Unnamed: 100 | Unnamed: 101 | Unnamed: 102 | IGR(rpiA-tp0617) | Unnamed: 104 | tp0617 | Unnamed: 106 | Unnamed: 107 | Unnamed: 108 | Unnamed: 109 | Unnamed: 110 | tp0618 | Unnamed: 112 | Unnamed: 113 | Unnamed: 114 | Unnamed: 115 | Unnamed: 116 | Unnamed: 117 | Unnamed: 118 | tprI | Unnamed: 120 | Unnamed: 121 | tp0668 | Unnamed: 123 | Unnamed: 124 | IGR(tp740-tp741) | [NAME] | Unnamed: 127 | Unnamed: 128 | Unnamed: 129 | Unnamed: 130 | tmpB | Unnamed: 132 | IGR(tex-fld) | Unnamed: 134 | Unnamed: 135 | Unnamed: 136 | tpF-1 | Unnamed: 138
BOSNIA | - | G | T | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | A | T | G | A | A | A | G | G | C | G | G | T | G | A | C | A | G | G | G | C | G | A | A | T | A | G | T | C | A | G | T | G | C | T | T | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | T | C | C | G | T | C | C | C | C | C | T | G | - | A | A | G | C | G | G | G | A | C | G | T | C | G | C | C | C | C | C | G | C | G | T | T | A | T | C | C | G | G | T | G | T | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
IRAQ | - | G | T | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | G | T | T | T | G | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | C | T | T | G | T | G | A | G | G | G | A | - | G | A | A | A | G | C | T | T | C | C | G | T | C | C | C | C | C | T | G | - | A | A | G | C | G | G | G | A | C | G | T | C | G | C | C | C | C | C | G | C | G | T | T | A | T | C | C | G | G | T | G | T | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
BRAZZAVILLE | - | G | T | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | C | C | T | G | T | G | A | G | G | A | A | - | C | A | A | A | G | C | T | C | - | C | G | T | C | G | C | C | C | T | G | - | A | G | G | C | G | G | G | A | C | G | T | C | G | C | C | C | T | G | G | C | G | T | T | A | T | C | C | G | A | T | G | - | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
CDC1 | - | G | T | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | C | T | T | G | T | G | A | G | G | A | G | - | G | A | A | A | G | C | T | C | - | C | A | T | C | G | C | C | C | T | - | - | A | G | G | C | G | G | G | A | C | G | T | C | G | C | C | C | T | G | G | C | G | T | T | A | T | C | C | G | A | T | A | - | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
CDC2 | - | G | T | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | C | T | T | G | T | G | A | G | G | A | A | - | C | A | A | A | G | C | T | C | - | C | G | T | C | G | C | C | C | T | G | - | A | G | G | C | G | G | G | A | C | G | T | C | G | C | C | C | T | G | G | C | G | T | T | A | T | C | C | G | A | T | G | - | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
CDC2575 | - | G | T | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | C | T | T | G | T | G | A | G | G | A | A | - | T | A | A | A | G | C | T | C | - | C | A | T | C | G | C | C | C | T | - | - | A | G | G | C | G | G | G | A | C | G | T | C | G | C | C | C | T | G | G | C | G | T | T | A | T | C | C | G | A | T | A | - | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
GAUTHIER | - | G | T | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | C | C | T | G | T | T | A | G | A | A | A | A | T | A | A | A | G | C | T | C | - | C | G | T | C | G | C | C | C | T | G | - | A | G | G | C | G | G | G | A | C | G | T | C | G | C | C | C | T | G | G | C | G | T | T | A | T | C | C | G | A | T | G | - | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
GHANA | - | G | T | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | C | T | T | G | T | T | A | G | A | A | A | A | T | A | A | A | G | C | T | C | - | C | A | T | C | G | C | C | C | T | - | - | A | G | G | C | G | G | G | A | C | G | T | C | G | C | C | C | T | G | G | C | G | T | T | A | T | C | C | G | A | T | A | - | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
PARIAMAN | - | G | T | A | C | G | C | C | G | T | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | A | T | T | G | T | G | A | G | G | G | A | - | G | A | A | A | A | C | - | C | - | C | G | T | C | G | C | C | C | T | G | - | A | G | G | C | G | G | G | A | A | G | T | C | G | C | C | C | T | G | G | C | G | T | T | A | T | C | C | G | A | T | G | - | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
SAMOA D | - | G | T | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | A | T | G | A | A | A | G | G | C | G | G | T | G | A | C | A | G | G | G | C | G | A | A | T | A | G | T | C | A | G | T | G | C | T | T | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | C | - | C | G | T | C | G | C | C | C | T | G | - | A | G | G | C | G | G | G | A | C | G | T | C | G | C | C | C | T | G | G | C | G | T | T | A | T | C | C | G | A | T | G | - | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
SAMOA F | - | G | T | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | C | T | T | G | T | G | A | G | G | A | A | - | C | A | A | A | G | C | T | C | - | C | G | T | C | G | C | C | C | T | G | - | A | G | G | C | G | G | G | A | C | G | T | C | G | C | C | C | T | G | G | C | G | T | T | A | T | C | C | G | A | T | G | - | A | G | C | A | C | A | A | T | A | A | A | T | G | - | G | G
SIMIAN | - | G | T | A | T | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | T | A | G | C | G | T | T | T | G | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | C | T | T | G | T | G | A | G | G | G | A | - | G | A | A | A | G | C | T | C | - | C | G | T | C | G | C | C | C | T | G | - | A | G | G | C | G | G | G | A | C | G | T | C | G | C | C | C | T | G | G | C | G | T | T | A | T | C | C | G | A | T | G | - | A | G | C | A | C | A | A | T | A | A | A | T | G | - | A | G
CHICAGO B | G | G | C | A | C | G | C | C | G | C | T | G | G | G | T | C | G | C | T | G | A | T | C | A | A | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | T | G | C | T | T | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | T | A | C | G | T | C | C | C | C | C | T | G | - | A | G | C | C | T | G | G | A | C | G | T | C | G | C | C | C | T | C | G | G | C | C | C | G | C | T | T | A | G | G | A | T | A | G | C | A | C | G | A | T | A | A | A | T | G | - | G | A
DALLAS | G | G | C | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | C | A | A | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | T | G | C | T | T | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | T | A | C | G | T | C | C | C | C | C | T | G | - | A | G | C | C | T | G | G | A | C | G | T | C | G | C | C | C | T | C | G | G | C | C | C | G | C | T | T | A | G | G | A | T | A | G | C | G | C | G | A | T | A | A | A | T | G | - | G | A
GRADY | G | G | C | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | C | A | A | C | A | T | G | A | A | A | G | G | C | G | G | T | G | A | C | A | G | G | G | C | G | G | A | T | A | G | T | C | A | G | T | G | C | T | G | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | T | C | C | G | T | C | C | C | C | C | T | G | - | A | G | C | C | T | G | G | A | C | G | T | C | G | C | C | C | T | C | G | G | C | C | C | G | C | T | T | A | G | G | A | - | A | G | C | A | C | G | A | T | A | A | A | T | G | - | G | A
HAITI B | G | G | C | A | C | G | C | C | G | C | T | G | G | G | T | C | G | C | T | G | A | T | C | A | A | T | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | A | A | T | A | G | T | C | A | G | T | G | C | T | T | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | T | C | C | G | T | C | C | C | C | C | T | G | - | A | G | C | C | T | G | G | A | C | G | T | C | G | C | C | C | T | C | G | G | C | C | C | G | C | T | T | A | G | G | A | T | A | G | C | A | C | G | A | T | A | A | A | T | G | - | G | A
MADRAS | G | G | C | A | C | G | C | C | G | C | T | G | G | G | T | C | G | C | T | G | A | T | C | A | A | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | T | G | C | T | T | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | T | A | C | G | T | C | C | C | C | C | T | G | - | A | G | C | C | T | G | G | A | C | G | T | C | G | C | C | C | T | C | G | G | C | C | C | G | C | T | T | A | G | G | A | - | A | G | C | G | C | G | A | T | A | A | A | T | G | - | G | A
MEXICO A | G | G | C | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | C | A | A | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | A | G | C | T | G | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | C | A | C | G | T | C | G | C | C | C | T | G | - | A | G | C | C | T | G | G | A | C | G | T | C | G | C | C | C | T | C | G | G | C | C | C | G | C | T | T | A | G | G | A | - | A | G | C | A | C | G | A | T | A | A | A | T | G | - | G | A
NICHOLS | G | G | C | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | C | A | A | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | T | G | C | T | T | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | T | - | C | G | T | C | C | C | C | C | T | G | - | A | G | C | C | T | G | G | A | C | G | T | C | G | C | C | C | T | C | G | G | C | C | C | G | C | T | T | A | G | G | A | T | A | G | C | G | C | G | A | T | A | A | A | T | G | - | G | A
PHILADELPHIA 1 | G | G | C | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | C | A | A | C | A | T | G | A | A | A | G | G | C | G | G | T | G | A | C | A | G | G | G | C | G | A | A | T | A | G | T | C | A | G | T | G | C | T | G | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | T | C | C | G | T | C | C | C | C | C | T | G | - | A | G | C | C | T | G | G | A | C | G | T | C | G | C | C | C | T | C | G | G | C | C | C | G | C | T | T | A | G | G | A | - | A | G | C | A | C | G | A | T | A | A | A | T | G | - | G | A
SOUTH AFRICA | G | G | C | A | C | G | C | C | G | C | T | G | G | G | T | - | G | C | T | G | A | T | C | A | A | C | G | T | T | T | A | C | G | G | C | G | A | C | G | A | C | G | G | G | G | G | G | G | A | T | A | G | T | C | A | G | T | G | C | T | G | G | T | G | A | G | G | A | A | - | C | A | A | G | G | C | T | C | - | C | G | T | C | G | C | C | C | T | G | - | A | G | C | C | T | G | G | A | C | G | T | C | G | C | C | C | T | C | G | G | C | C | C | G | C | T | T | A | G | G | A | - | A | G | C | A | C | G | A | T | A | A | A | T | G | - | G | A
TPC A | - | A | T | G | C | A | T | T | A | C | C | A | T | T | - | - | G | T | - | A | G | C | T | G | G | C | G | C | T | T | A | C | C | A | T | C | G | T | A | T | T | T | C | C | A | G | A | G | G | G | T | C | A | G | C | T | T | A | C | T | T | A | T | T | G | G | A | G | A | - | C | A | G | A | A | C | * | * | - | - | G | C | T | G | A | A | G | C | G | A | G | G | C | T | G | A | A | G | C | A | C | T | - | - | T | T | C | G | A | G | G | T | T | A | T | C | C | G | - | - | - | - | G | A | T | A | T | A | G | C | G | G | G | C | C | C | A | G
TPC H | - | A | T | G | C | A | T | T | A | C | C | A | T | T | - | - | G | T | - | A | G | C | T | G | G | C | G | C | T | T | A | C | C | A | T | C | G | T | A | T | T | T | C | C | A | G | A | G | G | G | T | C | A | A | C | T | T | A | C | T | T | A | C | T | G | G | A | A | A | - | C | A | G | A | A | G | * | * | - | - | G | C | T | G | A | A | G | C | G | A | G | G | C | T | G | A | A | G | C | A | C | T | - | - | T | T | C | G | A |  | - | - | - | - | - | - | - | - | - | - | - | - | G | A | T | A | T | A | G | C | G | G | G | C | C | C | A | G
TPC M | - | A | T | G | C | A | T | T | A | C | C | A | T | T | - | - | A | T | - | A | G | C | T | G | G | C | G | C | T | T | A | C | C | A | T | C | G | T | A | T | T | T | C | C | A | G | A | G | G | G | T | C | A | A | C | T | T | A | C | T | T | A | T | T | G | A | A | A | A | - | C | G | G | A | A | G | * | * | - | - | G | C | T | G | A | A | G | C | G | A | G | G | C | T | G | A | A | G | C | A | C | T | - | - | T | T | C | G | A |  | - | - | - | - | - | - | - | - | - | - | - | - | G | A | T | A | T | A | G | C | G | G | G | C | C | C | A | G
Class of Substitution | D | I | I | S | S | S | S | N | N | N | S | N | I | I | I | I | I | I | I | I | I | S | S | S | S | N | S | S | N | N | N | N | S | S | S | S | N | N | N | N | N | N | N | N | N | N | N | N | S | N | N | N | S | N | N | N | N | N | N | N | N | S | N | N | N | N | N | N/S/N/N | N/S/N/N | D | N/S/N/N | N | N | N | N | N | D | S | N/D | D | N | N | S | N |  |  | N | S | D | D | N | S | I | I | I | I | I | S | N | S | S | S | i | i | S | S | S | S | N | S | S | S |  |  |  |  | S | N | N | N | N | D | S | S | I | N | S | S | S | S | N | N | I | I | I | I | S | N
I=Intergenic
S=Synonymous
N=Non-synonymous
D=Deletion | *Only 1st nucleotide of indels is presented
polymorphisms in red were not included in analysis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | D: 2384-2398
Nucleotide Position In Gene/Genetic Region | 45-47 | 51 | 98 | 528 | 81 | 183 | 288 | 451 | 561 | 580 | 591 | 614 | 189 | 213 | 276-281 | 50-112 | 51 | 82 | 93-96 | 99 | 283 | 744 | 759 | 459 | 579 | 1592 | 1530 | 1533 | 1534 | 1537 | 1538 | 1539 | 1551 | 1554 | 1557 | 1560 | 1564 | 1565 | 1566 | 1567 | 1569 | 1571 | 1572 | 1573 | 1575 | 1578 | 1582 | 1586 | 1605 | 1606 | 1801 | 1803 | 1806 | 1813 | 1814 | 1815 | 1826 | 1827 | 1964 | 1966 | 1967 | 2010 | 2101 | 2111 | 2119 | 2120 | 2122 | 2125 | 2126 | 2127-2129 | 2127 | 2131 | 2132 | 2134 | 2135 | 2326 | 2359-2367 | 2373 | 2388 | 2382 -2399 | 2405 | 2408 | 2421 | 2494 | 2495 | 2496 | 16 | 84 | 107 | 110-126 | 131 | 210 | 20 | 43 | 115 | 127 | 136 | 573 | 623 | 669 | 684 | 759 | 28 | 31 | 216 | 234 | 246 | 255 | 256 | 264 | 300 | 303 | 304 | 306 | 313 | 315 | 318 | 320 | 137 | 143 | 151 | 310 | 408 | 417 | 13 | 92 | 121 | 303 | 426 | 462 | 674 | 811 | 27 | 37 | 41 | 58 | 117 | 122
Codon Substitution |  |  |  | [NAME] | TCC->TCT | ACG->ACA | ACC->ACT | CAT->TAT | ATG->ATA | CTT->TTT | TGT->TGC | GGG->GAG |  |  |  |  |  |  |  |  |  | GTT->GTC | AGC->AGT | GAA->GAG | CAA->CAG | GCG->GTG | [NAME] | GGT->GGC | TCA->GCA | TAC->AAA | TAC->TGC | TAC->AAA | CTG->CTC | CCG->CCA | CAC->CAT | CCG->CCC | ACG->GTG/GTA | ACG->GTG/GTA | ACG->GTG/GTA | AGC->TGT | AGC->TGT | AGG->AAG/ATC | AGG->AAG/ATC | GAG->CAA | GAG->CAA | CAG->CAC | GCT->ACT | [NAME] | GAA->GAG | TCG->GCG | [NAME] | [NAME] | GAT->GAA | CAG->ACT/GCT | CAG->ACT/GCT | CAG->ACT/GCT | CTG->CAG/CTA | CTG->CAG/CTA | CCC->CAC | TTT->CTT | TTT->TGT | GAG->GAA | TAT->CAT | CGG->CTG | AGC->GGC/GAC | AGC->GGC/GAC | GAA->AAA | AAC->GAG/AAT/AGG/GAC | AAC->GAG/AAT/AGG/GAC | - | AAC->GAG/AAT/AGG/GAC | AAG->AGG/GGG | AAG->AGG/GGG | GGC->AGC/AAC | GGC->AGC/AAC | CAG->GAG |  | AGT->AGC | AGA->AGC |  | GGA->GAA | CTG->CCG | AGC->AGT | GCC->CCC | GCC->GAA | GCC->GAA | CGG->GGG | TGT->TGC |  |  | AAG->AGG | CTG->CTA |  |  |  |  |  | GTA->GTG | CCG->CAG | CCG->CCA | AAT->AAC | TCC->TCT |  |  | [NAME] | TTC->TTT | TAT->TAC | CGC->CGG | GTT->ATT | CCG->CCC | ACG->ACC | CGT->CGC | TTA->CTG | TTA->CTG | TGC->CGT | TGC->CGT | GGC->GGT | CGG->CAG | CGC->CAC | GGC->GTC | AAG->GAG |  | TTA->TTG | GTG->GTA |  | TAT->TGT | CTA->TTA | AAA->AAG | AAA->AAG | CAT->CAC | AAG->AGG | AAC->GAC |  |  |  |  | TTG->TTA | CAG->CGG
Amino Acid Substitution |  |  |  |  |  |  |  | HIS->TYR | MET->ILE | LEU->PHE |  | GLY->GLU |  |  |  |  |  |  |  |  |  |  |  |  |  | ALA->VAL |  |  | SER->ALA | TYR->LYS | TYR->CYS | TYR->LYS |  |  |  |  | THR->VAL | THR->VAL | THR->VAL | SER->CYS | SER->CYS | ARG->LYS/ILE | ARG->LYS/ILE | GLU->GLN | GLU->GLN | GLN->HIS | ALA->THR | SER->ASN |  | SER->ALA | LYS->TYR | LYS->TYR |  | GLN->THR/ALA | GLN->THR/ALA | GLN->THR/ALA | VAL->GLN/LEU | VAL->GLN/LEU | PRO->HIS | PHE->LEU | PHE->CYS |  | TYR->HIS | ARG->LEU | SER->GLY/ASP | SER->GLY/ASP | GLU->LYS | ASN->GLU/ASN/ARG/ASP | ASN->GLU/ASN/ARG/ASP | - | ASN->GLU/ASN/ARG/ASP | LYS->ARG/GLY | LYS->ARG/GLY | GLY->SER/ASN | GLY->SER/ASN | GLN->GLU |  |  | ARG->SER |  | GLY->GLU | LEU->PRO |  | ALA->PRO | ALA->GLU |  | ARG->GLY |  |  |  | LYS->ARG |  |  |  |  |  |  |  | PRO->GLN |  |  |  |  |  |  |  |  |  | VAL->ILE |  |  |  | LEU->LEU |  | CYS->ARG |  |  | ARG->GLN | [NAME] | GLY->VAL | LYS->GLU |  |  |  |  | TYR->CYS |  |  |  |  | LYS->ARG | ASN->ASP |  |  |  |  |  | GLN->ARG
Radical or Conservative Amino Acid Change? |  |  |  |  |  |  |  | R | C | C |  | R |  |  |  |  |  |  |  |  |  |  |  |  |  | C |  |  | C | R | R | R |  |  |  |  | C |  |  | R |  | C/R |  | C |  | R | C | C |  | C | R |  |  | C/C |  |  | C/C |  | R | C | R |  | R | R | C/R |  | R | [NAME]/C |  |  |  | R/R |  | C/C |  | C |  |  | R |  | R | C |  | C | R |  | R |  |  |  | C |  |  |  |  |  |  |  | R |  |  |  |  |  |  |  |  |  | C |  |  |  |  |  | R |  |  | R | C | R | R |  |  |  |  | R |  |  |  |  | C | C |  |  |  |  |  | R
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | * ALIGNMENT WITH TPC NOT POSSIBLE IN THIS REGION