Spreadsheet: 29bea698-9e00-4a7f-aa1e-4a1d66c5ad9e
Sheet: Sheet1

Supplementary table 4: Categories of differentially regulated genes identified by [NAME]
ST3 - STV |  | P-Value | [NAME] |  | ST3- ST6 |  |  |  |  | Sp6- SpV
Downregulated in STV |  |  |  |  | Downregulated in ST3 |  |  |  |  | Downregulated in STV
 | Lipid metabolic proc. | 9.71450327715458e-07 | 0.0015876381032176 |  |  | None Significant |  |  |  |  | None Significant
 | Electron transport | 1.071703186127e-07 | 0.00016050942539536 |  | Upregulated in ST6 |  |  |  |  | Upregulated in ST6
Upregulated in ST3 |  |  |  |  |  | None Significant |  |  |  |  | None Significant
 | None Significant
SR3 - SRV |  | P-Value | [NAME] |  | SR3 - SR6 |  | P-Value | [NAME] |  | SR6 - SRV |  | P-Value | [NAME]
Downregulated in SRV |  |  |  |  | Downregulated in SR3 |  |  |  |  | Downregulated in SRV
 | Electron transport | 6.41992960234967e-08 | 9.61515775776966e-05 |  |  | Serine-type peptidase activity | 9.4493525950974e-06 | 0.0170031212450294 |  |  | Electron Transport | 2.15893972561332e-08 | 3.23345481056946e-05
 | Oxidative phosphorylation | 1.91102700999469e-05 | 0.0286177291138112 |  |  |  |  |  |  | Upregulated in SR6
 | Co-enzyme metabolic proc. | 2.67114303453862e-05 | 0.0436457843631776 |  | Upregulated in SR6 |  |  |  |  |  | Gamete generation | 8.72488423563198e-18 | 1.30673046621243e-14
Upregulated in SR3 |  |  |  |  |  | None significant |  |  |  |  | Cell cycle proc. | 7.165526025793e-15 | 1.0813572259849e-11
 | Defense response to bacterium | 3.19529413058745e-11 | 4.78561634764673e-08 |  |  |  |  |  |  |  | Protein kinase regulator activity | 2.28592462355302e-12 | 3.02422531461843e-09
 | Protein kinase regulator activity | 1.91781061135087e-10 | 2.68268096625945e-07 |  |  |  |  |  |  |  | [NAME] cell divison | 7.12687801432822e-10 | 1.06739622696139e-06
 | Gamete generat. | 3.62041251884046e-08 | 5.91687081996639e-05 |  |  |  |  |  |  |  | Defense response to bacterium | 6.14530878588829e-07 | 0.000920382151925469
 | Cell cycle proc. | 2.86819138723608e-07 | 0.000429569660242989 |  |  |  |  |  |  |  | Regulation of translation | 1.00403439364709e-08 | 1.50374743990155e-05
 | Fertilization | 2.22770761334361e-06 | 0.00333639737816193 |  |  |  |  |  |  |  | DNA metabolic proc. | 1.72092521235245e-09 | 2.81252333644843e-06
 | Regulation of Translation | 7.27067413868571e-07 | 0.00108892712786801 |  |  |  |  |  |  |  | Fertilization | 1.21975794843548e-05 | 0.0182668212919012
 | Peptidoglycan metabolic proc. | 2.7844162353126e-05 | 0.0454962437490991 |  |  |  |  |  |  |  | Embryonic development | 7.64715994143807e-07 | 0.00114531301536047
 |  |  |  |  |  |  |  |  |  |  | Nervous system development | 1.36496157964812e-05 | 0.0223053530728489
 |  |  |  |  |  |  |  |  |  |  | Organelle localization | 7.94386932823725e-05 | 0.118909717775617
 |  |  |  |  |  |  |  |  |  |  | Chromatin assembly | 5.03022956495889e-05 | 0.0821777737251117
STV - SRV |  | P-Value | [NAME] |  | ST3 - SR3 |  | P-Value | [NAME] |  | ST6 - SR6 |  | P-Value | [NAME]
Upregulated in STV |  |  |  |  | Upregulated in ST3 |  |  |  |  | Upregulated in ST6
 | [NAME] proc. | 2.34373237753402e-09 | 3.07028477397608e-06 |  |  | Macromolecule biosynthetic proc. | 1.16421655462647e-05 | 0.0174351135164729 |  |  | [NAME] proc. | 8.77967585631634e-17 | 1.77635683940025e-13
 | Electron transport | 3.02550208417272e-05 | 0.0453035229826315 |  |  | Protein targeting to ER | 4.06888868556891e-05 | 0.0664774575461435 |  |  | Lipid metabolic proc. | 8.3471452477039e-07 | 0.00125014900808073
 | Lipid metabolic proc. | 1.00835813728577e-06 | 0.00151021260332839 |  | Upregulated in SR3 |  |  |  |  |  | Monosaccharide metabolic proc. | 3.58131504543087e-07 | 0.000585295904087512
 | Heterocycle metabolic proc. | 9.24440320045323e-06 | 0.0138444964853046 |  |  | Ion transmembrane transporter activity | 7.29112496203659e-07 | 0.00101989591625439 |  |  | Cellular biosynthetic proc. | 4.74928048486297e-07 | 0.000711299856359648
 | Arginine metabolic proc. | 8.5337893934903e-05 | 0.13937721213143 |  |  | Protein kinase CK2 regulator activity | 1.12989441256848e-08 | 1.58052436916023e-05 |  |  | Coenzyme metabolic proc. | 2.15715333719448e-05 | 0.0352487158227998
 | Monosaccharide metabolic proc. | 0.000138868963943643 | 0.226713162937808 |  |  | Tissue development | 1.60295462853927e-11 | 2.6197177760423e-08 |  |  | Heme binding | 3.36901485717022e-05 | 0.0445616351810174
Upregulated in SRV |  |  |  |  |  | Cell motility | 2.54683073404958e-05 | 0.0381372284936953 |  |  | Peptidase activity | 8.49618425332849e-05 | 0.112342987113045
 | Organ development | 1.01089055405086e-11 | 1.65210845004537e-08 |  |  | Embryonic development | 9.45314519869968e-05 | 0.141486754373765 |  | Upregulated in SR6
 | Transmission of nerve impulse | 2.24759087638097e-08 | 3.67325718841904e-05 |  |  |  |  |  |  |  | Cell fate commitment | 3.72309431333145e-08 | 6.08468450069565e-05
 | Ion transport | 8.77278639071582e-08 | 0.000143374333883006 |  |  |  |  |  |  |  | Transmission of nerve impulse | 6.78248439605357e-07 | 0.00110846170673362
 | Nervous system development | 3.8345756620291e-07 | 0.000626686277127586 |  |  |  |  |  |  |  | Regulation of developmental proc. | 7.30901514937334e-09 | 1.09467496178794e-05
 | Regulation of developmental proc. | 0.000105035162504556 | 0.157196290355798 |  |  |  |  |  |  |  | Open tracheal system development | 8.01761907797637e-08 | 0.000131032583128298
 | Embryonic development | 3.4211590859009e-06 | 0.0051237653163394 |  |  |  |  |  |  |  | Chemosensory behavior | 1.01952538130927e-06 | 0.00152693760595568
 |  |  |  |  |  |  |  |  |  |  | Ion transport | 1.03106148190825e-05 | 0.0154411489761474
 |  |  |  |  |  |  |  |  |  |  | Protein kinase CK2 regulator activity | 1.9237035971355e-06 | 0.00269089095649155
 |  |  |  |  |  |  |  |  |  |  | Regulation of signal transduction | 4.63594661193734e-05 | 0.0694103237616095
 |  |  |  |  |  |  |  |  |  |  | Embryonic development | 6.49121997600576e-12 | 9.72197877757707e-09
[NAME] categorization of differentially expressed genes (abs (FC) [NAME] 2, [NAME] ≤ 0.05). Categories listed are considered to be overrepresented compared to chance (p ≤ 0.05, [NAME]). ST = spermathecae, SR = Seminal receptacle, V = virgin, 3 = 3 hours post-mating, 6 = 6 hours post-mating.