Spreadsheet: 4775cb04-c3b5-409c-893f-096d1245cdb0
Sheet: Sheet1

Table S2. General information of the six libraries | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14 | Unnamed: 15 | Unnamed: 16 | Unnamed: 17 | Unnamed: 18 | Unnamed: 19 | Unnamed: 20 | Unnamed: 21 | Unnamed: 22 | Unnamed: 23 | Unnamed: 24
 | SjC |  | SjL |  | SjM |  | SjF |  | SjE30 |  | SjE45
 | % | % | % | % | % | % | % | % | % | % | % | %
Total Reads | 22031609 | 100 | 15807920 | 100 | 16058381 | 100 | 25696788 | 100 | 9489936 | 100 | 12655146 | 100
Low Quality | 915380 | 4.154848608651324 | 354342 | 2.241547275036817 | 423101 | 2.634767477493528 | 1903778 | 7.408622431721816 | 397168 | 4.185149404590295 | 580419 | 4.586426738972431
High Quality | 21116229 | 95.84515139134867 | 15453578 | 97.75845272496319 | 15635280 | 97.36523252250647 | 23793010 | 92.59137756827819 | 9092768 | 95.81485059540971 | 12074727 | 95.41357326102758
adaptor 3 null | 7590 | 0.03445050245762804 | 6850 | 0.04333270917362942 | 7130 | 0.04440049093367507 | 7065 | 0.02749370855221283 | 17791 | 0.1874722864305934 | 57634 | 0.455419479158913
insert null | 25542 | 0.115933430009583 | 4889 | 0.0309275350583758 | 8033 | 0.05002372281489648 | 64483 | 0.2509379771510743 | 204303 | 2.152838543905881 | 664549 | 5.251215592455432
5' adaptor contaminants | 134057 | 0.6084757586248013 | 173679 | 1.098683444754275 | 174398 | 1.086024799137597 | 226360 | 0.8808883040168289 | 204303 | 2.152838543905881 | 65916 | 0.5208632124828904
size < 18 nt | 1527341 | 6.932498665894079 | 1953902 | 12.36027257222962 | 1865450 | 11.61667542948445 | 4179568 | 16.26494330731141 | 93499 | 0.9852437361010654 | 170640 | 1.348384285728509
polyA | 50 | 0.0002269466565061136 | 264 | 0.001670048937494623 | 239 | 0.001488319401563582 | 291 | 0.001132437252469063 | 45 | 0.0004741865487817832 | 43 | 0.0003397827255410566
size >= 18 nt | 19421649 | 88.15356608770608 | 13313994 | 84.2235664148098 | 13580030 | 84.56661976073428 | 19315243 | 75.1659818339942 | 8754341 | 92.24868323664143 | 11115945 | 87.83735090847628
The abbreviations of SjC, SjL, SjM, SjF, [NAME], and SjE45 represented cercariae, lung-stage schistosomula, male adult worms, female adult worms, liver eggs 30d post infection and liver eggs 45d post infection, respectively.
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | SjE30 |  |  |  | SjE45
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | # of Unique | % | Total sequences | % | # of Unique | % | Total sequences | %
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 151756 | 2.040638773346909 | 1780347 | 2.412246534328161 | 215964 | 2.904033527814992 | 2111022 | 2.860288192914361
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 15774 | 0.9852130599753292 | 101160 | 0.2553080656754508 | 20800 | 1.299127148946801 | 124413 | 0.3139940922783696
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 113 | 0.7163687080005071 | 4588 | 4.535389482008699 | 225 | 1.081730769230769 | 15412 | 12.38777298192311
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 475 | 3.01128439203753 | 964 | 0.9529458283906682 | 797 | 3.831730769230769 | 1716 | 1.379277085192062
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 495 | 3.138075313807531 | 1147 | 1.133847370502175 | 527 | 2.533653846153846 | 1290 | 1.036869137469557
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 465 | 2.94788893115253 | 1105 | 1.092328983788059 | 473 | 2.274038461538461 | 1210 | 0.9725671754559412
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 4 | 0.02535818435400026 | 10 | 0.009885330170027679 | 6 | 0.02884615384615385 | 17 | 0.01366416692789339
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 26 | 0.1648281983010016 | 32 | 0.03163305654408857 | 48 | 0.2307692307692308 | 63 | 0.05063779508572255
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1936 | 12.27336122733612 | 3217 | 3.180110715697904 | 2864 | 13.76923076923077 | 4929 | 3.961804634563912
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 180 | 1.141118295930011 | 262 | 0.2589956504547252 | 302 | 1.451923076923077 | 504 | 0.4051023606857804
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 551 | 3.493089894763535 | 1192 | 1.178331356267299 | 842 | 4.048076923076923 | 1717 | 1.380080859717232
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 8596 | 54.49473817674655 | 33595 | 33.20976670620799 | 10462 | 50.29807692307692 | 32874 | 26.42328374044513
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 2002 | 12.69177126917713 | 2524 | 2.495057334914986 | 2767 | 13.30288461538462 | 3988 | 3.205452806378754
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 46 | 0.2916191200710029 | 60 | 0.05931198102016608 | 67 | 0.3221153846153846 | 100 | 0.08037745251701993
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1876 | 11.89298846202612 | 3537 | 3.49644128113879 | 2707 | 13.01442307692308 | 4245 | 3.412022859347496
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 1113 | 7.05591479650057 | 2023 | 1.9998022933966 | 1085 | 5.216346153846154 | 1748 | 1.404997869997508
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 244 | 1.546849245594015 | 571 | 0.5644523527085805 | 201 | 0.966346153846154 | 298 | 0.2395248085007194
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 3315 | 21.01559528337771 | 24880 | 24.59470146302887 | 3635 | 17.47596153846154 | 22495 | 18.08090794370363
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 4159 | 26.36617218207176 | 57649 | 56.98793989719256 | 5925 | 28.48557692307692 | 68192 | 54.81099242040622