Spreadsheet: 6ee25b31-48d6-41fb-b734-33274b50ce23
Sheet: Sheet1

Table S2A: Genes significantly increased in ONH astrocytes from normal AA donors compared to their caucasian counterpart using RMA SAM (p<0.05) | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME]
10965 | ACOT2 | acyl-CoA thioesterase 2 | 1.43 | 0.00150389 | 14q24.3 | Hs.446685
100 | ADA | adenosine deaminase | 1.55 | 0.02971259 | 20q12-q13.11 | Hs.654536
115 | ADCY9 | adenylate cyclase 9 | 1.21 | 0.021551669 | 16p13.3 | Hs.391860;Hs.610484
165 | AEBP1 | AE binding protein 1 | 1.48 | 0.025192125 | [NAME] | Hs.439463
249 | ALPL | alkaline phosphatase, liver/bone/kidney | 1.34 | 0.022271343 | 1p36.1-p34 | Hs.75431
267 | AMFR | autocrine motility factor receptor | 2.79 | 3.75e-07 | 16q21 | Hs.295137
23229 | ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 | 1.28 | 0.00821862 | Xq11.1 | Hs.54697
84159 | ARID5B | AT rich interactive domain 5B | 1.21 | 0.010042295 | 10q21.2 | Hs.535297
155066 | ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 1.27 | 0.003723735 | 7q36.1 | Hs.556998
10409 | BASP1 | brain abundant, membrane attached signal protein 1 | 1.28 | 0.023336866 | 5p15.1-p14 | Hs.201641
683 | BST1 | bone marrow stromal cell antigen 1 | 1.41 | 0.000719998 | 4p15 | Hs.169998
6936 | C2orf3 | chromosome 2 open reading frame 3 | 1.48 | 0.003016512 | 2p11.2-p11.1 | Hs.303808; Hs.44024
771 | CA12 | carbonic anhydrase XII | 1.76 | 0.007457753 | 15q22 | Hs.210995
785 | CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 1.38 | 0.006385002 | 2q22-q23 | Hs.614033
55013 | CCDC109B | coiled-coil domain containing 109B | 1.27 | 0.046671018 | 4q25 | [NAME]
778642 | CDC2L2 | cell division cycle 2-like 2 | 1.35 | 0.020839109 | 1p36.33 | Hs.651228
8814 | CDKL1 | cyclin-dependent kinase-like 1 | 1.31 | 0.010530446 | 14q22.1 | Hs.700582
51816 | [NAME] | cat eye syndrome chromosome region, candidate 1 | 1.6 | 0.045802192 | 22q11.2 | Hs.170310
1059 | CENPB | centromere protein B, 80kDa | 1.3 | 0.049026064 | 20p13 | Hs.516855
116987 | CENTG2 | centaurin, gamma 2 | 1.35 | 0.010340437 | 2p24.3-p24.1 | Hs.435039
1066 | [NAME] | carboxylesterase 1 | 1.75 | 0.010565966 | 16q13-q22.1 | Hs.558865
90634 | CG018 | hypothetical gene CG018 | 1.25 | 0.040213079 | 13q12-q13 | Hs.161220
8418 | CMAH | [NAME] acid hydroxylase | 1.6 | 0.047066252 | 6p21.32 | Hs.484918
80781 | COL18A1 | collagen, type XVIII, alpha 1 | 1.41 | 0.016863257 | 21q22.3 | Hs.84190;Hs.517356
1384 | CRAT | carnitine acetyltransferase | 1.24 | 0.01338133 | 9q34.1 | Hs.12068
83716 | CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | 1.51 | 0.038911079 | 16q24.1 | Hs.513779
1415 | CRYBB2 | crystallin, beta B2 | 2.18 | 1.808e-06 | 22q11.2-q12.1;22q11.23 | [NAME]
1429 | CRYZ | crystallin, zeta | 1.32 | 0.045772507 | 1p31-p22 | Hs.83114
6376 | CX3CL1 | chemokine (C-X3-C motif) ligand 1 | 1.48 | 0.049798778 | 16q13 | Hs.531668
1627 | DBN1 | drebrin 1 | 1.25 | 0.014634767 | 5q35.3 | [NAME]
10521 | DDX17 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 2.44 | 0.000124461 | 22q13.1 | Hs.528305;Hs.665429;Hs.699523
55619 | DOCK10 | dedicator of cytokinesis 10 | 1.24 | 0.047157426 | 2q36.2 | Hs.46578
10231 | [NAME] | regulator of calcineurin 2 | 1.39 | 0.026828918 | 6p12.3 | Hs.440168
80303 | EFHD1 | EF-hand domain family, member D1 | 1.49 | 0.013850867 | 2q37.1 | Hs.516769; Hs.753499
1948 | EFNB2 | ephrin-B2 | 2.05 | 0.015305055 | 13q33 | Hs.149239
1984 | EIF5A | eukaryotic translation initiation factor 5A | 1.49 | 0.018258405 | 17p13-p12 | Hs.534314
2006 | ELN | [NAME] | 2.2 | 0.002296764 | 7q11.23 | Hs.647061
23136 | EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 1.65 | 0.001927247 | 18p11.32 | Hs.213394
9638 | FEZ1 | fasciculation and elongation protein zeta 1 | 1.41 | 0.023194329 | 11q24.2 | Hs.224008
2254 | FGF9 | fibroblast growth factor 9 | 1.51 | 0.026820094 | 13q11-q12 | Hs.111
55020 | FLJ20699 | hypothetical protein FLJ20699 | 1.21 | 0.020639224 | 22q13 | Hs.435832
2355 | FOSL2 | FOS-like antigen 2 | 1.23 | 0.029173362 | 2p23.3 | Hs.220971;Hs.596972
2674 | [NAME] | GDNF family receptor alpha 1 | 1.49 | 0.006027164 | 10q26 | Hs.591913
2678 | GGT1 | gamma-glutamyltransferase 1 | 1.57 | 0.00132415 | 22q11.23 | Hs.595809;Hs.645535
728441 | [NAME] | gamma-glutamyltransferase 2 | 1.54 | 0.001874882 | 22q11.21 | [NAME]
92086 | GGTLA4 | gamma-glutamyltransferase-like activity 4 | 1.44 | 0.009060544 | 20p11.1 | Hs.355394;Hs.450000
11010 | GLIPR1 | GLI pathogenesis-related 1 | 1.31 | 0.031873092 | 12q21.2 | Hs.205558
9289 | GPR56 | G protein-coupled receptor 56 | 1.62 | 0.00514293 | 16q12.2-q21 | Hs.513633
2944 | GSTM1 | glutathione S-transferase M1 | 1.27 | 0.021866543 | 1p13.3 | Hs.301961
2946 | GSTM2 | glutathione S-transferase M2 | 1.3 | 0.002089327 | 1p13.3 | Hs.279837
2947 | GSTM3 | glutathione S-transferase M3 | 1.31 | 0.014530713 | 1p13.3 | Hs.2006
2948 | GSTM4 | glutathione S-transferase M4 | 1.42 | 0.024462266 | 1p13.3 | Hs.348387
2953 | GSTT2 | glutathione S-transferase theta 2 | 2.82 | 2.2e-09 | 22q11.2;22q11.23 | Hs.654462
23493 | HEY2 | hairy/enhancer-of-split related with YRPW motif 2 | 1.51 | 0.011733783 | 6q21 | Hs.144287
11147 | HHLA3 | HERV-H LTR-associating 3 | 1.33 | 0.038355006 | 1p31.1 | Hs.142245
3105 | HLA-A | major histocompatibility complex, class I, A | 1.25 | 0.015051362 | 6p21.3 | Hs.181244;Hs.652059
3106 | HLA-B | major histocompatibility complex, class I, B | 1.34 | 0.008714164 | 6p21.3 | Hs.77961;Hs.622401;Hs.653575
3134 | HLA-F | major histocompatibility complex, class I, F | 1.37 | 0.000692391 | 6p21.3 | Hs.519972
3135 | [NAME] | HLA-G histocompatibility antigen, class I, G | 1.28 | 0.005589922 | 6p21.3 | Hs.181244;Hs.512152
3241 | HPCAL1 | hippocalcin-like 1 | 1.29 | 0.04667982 | 2p25.1 | Hs.580427;Hs.467696
3306 | HSPA2 | heat shock 70kDa protein 2 | 1.78 | 0.000507916 | 14q24.1 | Hs.432648
126393 | HSPB6 | heat shock protein, alpha-crystallin-related, [NAME] | 1.5 | 0.019344278 | 19q13.12 | Hs.534538
29092 | HSPC157 | HSPC157 protein | 1.3 | 0.004657767 | 1p36.12 | Hs.279842
3486 | IGFBP3 | insulin-like growth factor binding protein 3 | 1.74 | 0.048828594 | 7p13-p12 | Hs.450230;Hs.697535
3488 | IGFBP5 | insulin-like growth factor binding protein 5 | 1.46 | 0.01132232 | 2q33-q36 | Hs.635441
3600 | IL15 | interleukin 15 | 1.38 | 0.034475838 | 4q31 | Hs.654378
3638 | INSIG1 | insulin induced gene 1 | 1.23 | 0.016785016 | 7q36 | Hs.520819
3776 | KCNK2 | potassium channel, subfamily K, member 2 | 1.49 | 0.037106807 | 1q41 | Hs.497745
11103 | KRR1 | KRR1, small subunit (SSU) processome component, homolog | 1.33 | 0.030357862 | 12q21.2 | Hs.645517
25802 | LMOD1 | leiomodin 1 | 1.33 | 0.024708787 | 1q32 | Hs.519075
388796 | LOC388796 | hypothetical LOC388796 | 1.54 | 0.001442521 | 20q11.23 | [NAME]
728215 | LOC728215 | similar to transmembrane protein 28 | 1.36 | 0.01559191 | 13q33.3 | Hs.593580;Hs.653511
64167 | LRAP | leukocyte-derived arginine aminopeptidase | 1.97 | 0.016560539 | 5q15 | Hs.591249
4047 | LSS | lanosterol synthase | 1.44 | 0.003172472 | 21q22.3 | Hs.596543
4052 | LTBP1 | latent transforming growth factor beta binding protein 1 | 1.539 | 0.0239 | [NAME] | Hs.654497
338645 | LUZP2 | [NAME] protein 2 | 1.65 | 0.006797926 | 11p14.3 | Hs.144138;Hs.655032
84809 | CROCCL1 | [NAME] rootlet coiled-coil, rootletin-like 1 | 1.36 | 0.01090096 | 1p36.13 | Hs.631865
64780 | MICAL1 | microtubule associated monoxygenase, calponin and LIM domain containing 1 | 1.46 | 0.007903264 | 6q21 | Hs.33476
57553 | [NAME] | microtubule associated monoxygenase, calponin and LIM domain containing 3 | 1.2 | 0.045153176 | 22q11.21 | Hs.528024;Hs.646433
4281 | MID1 | midline 1 | 1.56 | 0.019157699 | Xp22 | Hs.27695
4487 | MSX1 | [NAME] 1 | 2.01 | 0.000403566 | 4p16.3-p16.1 | Hs.424414;Hs.621772
57509 | MTUS1 | mitochondrial tumor suppressor 1 | 1.42 | 0.036478962 | 8p22 | Hs.7946
4638 | MYLK | [NAME], light chain kinase | 1.47 | 0.043535348 | 3q21 | Hs.556600
4771 | NF2 | neurofibromin 2 | 1.25 | 0.040123896 | 22q12.2 | Hs.187898
4781 | NFIB | nuclear factor I/B | 1.43 | 0.024243397 | 9p24.1 | Hs.699215
22871 | NLGN1 | neuroligin 1 | 1.73 | 0.00445739 | 3q26.31 | Hs.478289
4883 | [NAME] | natriuretic peptide receptor C/guanylate cyclase C | 1.35 | 0.040378739 | 5p14-p13 | [NAME]
4835 | NQO2 | NAD(P)H dehydrogenase, quinone 2 | 1.54 | 0.001735359 | 6pter-q12 | Hs.533050
23363 | OBSL1 | obscurin-like 1 | 1.22 | 0.018788075 | 2q35 | Hs.526594
11054 | OGFR | opioid growth factor receptor | 1.25 | 0.031918426 | 20q13.3 | Hs.67896
5021 | OXTR | oxytocin receptor | 1.38 | 0.027826439 | 3p25 | Hs.2820
64761 | PARP12 | poly (ADP-ribose) polymerase family, member 12 | 1.24 | 0.006027862 | 7q34 | Hs.12646
9659 | PDE4DIP | phosphodiesterase 4D interacting protein | 1.48 | 0.020533606 | 1q12 | [NAME]
64236 | PDLIM2 | PDZ and LIM domain 2 | 1.24 | 0.042796549 | 8p21.2 | Hs.632034
9260 | PDLIM7 | PDZ and LIM domain 7 | 1.24 | 0.039097745 | 5q35.3 | Hs.533040
8863 | PER3 | period homolog 3 | 1.47 | 0.027726857 | 1p36.23 | Hs.533339
5190 | PEX6 | peroxisomal biogenesis factor 6 | 1.31 | 0.030570266 | 6p21.1 | Hs.656425
10404 | PGCP | plasma glutamate carboxypeptidase | 1.32 | 0.002887067 | 8q22.2 | Hs.156178
8605 | PLA2G4C | phospholipase A2, group IVC | 1.6 | 0.001558496 | 19q13.3 | Hs.631562
51082 | POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 1.22 | 0.044027782 | 13q12.2 | Hs.507584
8611 | [NAME] | phosphatidic acid phosphatase type 2A | 1.29 | 0.039872021 | 5q11 | Hs.696231
4660 | PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 1.53 | 0.002611705 | 1q32.1 | Hs.444403
5696 | PSMB8 | proteasome subunit, beta type, 8 | 1.34 | 0.00403762 | 6p21.3 | Hs.180062
5698 | PSMB9 | proteasome subunit, beta type, 9 | 1.54 | 0.005308842 | 6p21.3 | Hs.654585
5723 | PSPH | phosphoserine phosphatase | 2.7 | 9.37e-06 | 7p15.2-p15.1 | Hs.512656
5747 | PTK2 | PTK2 protein tyrosine kinase 2 | 1.33 | 0.039265115 | 8q24-qter | Hs.395482
5763 | PTMS | [NAME] | 1.32 | 0.013854452 | 12p13 | Hs.504613
25797 | QPCT | glutaminyl-peptide cyclotransferase | 1.29 | 0.042694833 | 2p22.2 | Hs.79033
5865 | RAB3B | RAB3B, member RAS oncogene family | 1.77 | 0.000320408 | 1p32-p31 | Hs.123072
5959 | RDH5 | [NAME] dehydrogenase 5 | 1.24 | 0.03524019 | 12q13-q14 | Hs.632719
8490 | RGS5 | regulator of G-protein signalling 5 | 2.04 | 0.000612139 | 1q23.1 | Hs.24950
54913 | RPP25 | ribonuclease P 25kDa subunit | 1.4 | 0.003451743 | 15q24.1 | Hs.8562
6231 | RPS26 | ribosomal protein S26 | 1.27 | 0.009036786 | 12q13 | Hs.447562;Hs.567235;Hs.632726
6253 | RTN2 | reticulon 2 | 1.22 | 0.030432726 | 19q13.32 | Hs.47517
862 | RUNX1T1 | runt-related transcription factor 1; translocated to, 1 | 1.45 | 0.039184637 | 8q22 | Hs.368431
23328 | SASH1 | SAM and SH3 domain containing 1 | 1.2 | 0.032630092 | 6q24.3 | Hs.193133
7536 | SF1 | splicing factor 1 | 1.37 | 0.017220438 | 11q13 | Hs.502829;hs.658141
6442 | SGCA | sarcoglycan, alpha | 1.84 | 4.007e-06 | 17q21 | Hs.463412
63898 | SH2D4A | SH2 domain containing 4A | 1.25 | 0.029717911 | 8p21.2 | Hs.303208
6509 | SLC1A4 | solute carrier family 1, member 4 | 1.33 | 0.01046319 | 2p15-p13 | Hs.654352
55089 | SLC38A4 | solute carrier family 38, member 4 | 1.41 | 0.017602051 | 12q13 | Hs.446077
23583 | SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 1.2 | 0.035193616 | 12q13.11-q13.3 | Hs.632721
6654 | SOS1 | son of sevenless homolog 1 | 1.67 | 9.06e-05 | [NAME] | Hs.654397
63826 | SRR | serine racemase | 1.25 | 0.013727242 | 17p13 | Hs.461954
85360 | SYDE1 | synapse defective 1, Rho GTPase, homolog 1 | 1.34 | 0.001151295 | 19p13.12 | Hs.528701;Hs.701386
7045 | TGFBI | transforming growth factor, beta-induced, 68kDa | 1.24 | 0.044450866 | 5q31 | Hs.369397;Hs.645734
25816 | TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 1.27 | 0.032698728 | 5q23.1 | Hs.656274
9760 | TOX | [NAME] group box protein TOX | 1.92 | 0.002368804 | 8q12.1 | Hs.491805;Hs.634856
9537 | TP53I11 | tumor protein p53 inducible protein 11 | 1.23 | 0.012111495 | 11p11.2 | Hs.554791
54476 | RNF216 | ring finger protein 216 | 1.2 | 0.049592333 | 7p22.1 | Hs.487458;Hs.68946
57418 | WDR18 | WD repeat domain 18 | 1.26 | 0.010512923 | 19p13.3 | [NAME]
8839 | WISP2 | WNT1 inducible signaling pathway protein 2 | 2 | 7.48e-05 | 20q12-q13.1 | Hs.592145
678 | ZFP36L2 | zinc finger protein 36, C3H type-like 2 | 1.65 | 0.022706337 | 2p22.3-p21 | Hs.503093;Hs.645068
54764 | ZRANB1 | zinc finger, RAN-binding domain containing 1 | 1.26 | 0.044006371 | 10q26.13 | Hs.595158
FC: fold change; CL: Chromosome location