Spreadsheet: 78f75137-c348-49ed-9320-16204e8a7276
Sheet: Sheet1

Dataset of HV4a1a control region sequences (defined by motif 16221 16291) found in the literature | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14 | Unnamed: 15
Sample ID | Continent | Country | Region/Ethnicity | Sub-region | Franco Cantabrian region | GenBank | HVS-I | HVS-I sequence range | HVS-II | HVS-II sequence range | Heteroplasmies | HG [1] | RFLPs and coding region information [2] | N | Reference [2]
1013Ast | Europe | Spain | Asturias | – | YES | GQ888730 | 16291 | 16024-16569 | 263 309+C 315+C 345 | 1-576 | – | HV4a1a3 | Complete genome | 76 | [NAME]. (2010)
GP24 | Europe | England | – | – | NO | JN214425 | 16172 16221 16291 16300 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a5 | Complete genome | 200000 | This study
GP29 | Europe | Scotland | – | – | NO | JN214426 | 16172 16221 16291 16300 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a5 | Complete genome | 200000 | This study
GP37 | Europe | Ireland | – | County Sligo | NO | JN214424 | 16172 16221 16291 16300 | 16024-16569 | 263 309+CC 315+C | 1-576 | – | HV4a1a5 | Complete genome | 200000 | This study
GP1 | – | – | – | – | NO | – | 16172 16221 16291 16300 | 16024-16569 | n.d. | – | – | HV4a1a5 | – | 200000 | This study
GP9 | America | USA | – | – | NO | – | 16172 16221 16291 16300 | 16024-16569 | n.d. | – | – | HV4a1a5 | – | 200000 | This study
GP12 | America | USA | – | – | NO | – | 16172 16221 16291 16300 | 16024-16569 | n.d. | – | – | HV4a1a5 | – | 200000 | This study
GP25 | America | USA | – | – | NO | – | 16172 16221 16291 16300 | 16024-16569 | n.d. | – | – | HV4a1a5 | – | 200000 | This study
GP30 | America | USA | Hampshire | – | NO | – | 16172 16221 16291 16300 | 16024-16569 | n.d. | – | – | HV4a1a5 | – | 200000 | This study
GP31 | America | USA | – | – | NO | – | 16172 16221 16291 16300 | 16024-16569 | n.d. | – | – | HV4a1a5 | – | 200000 | This study
GP36 | America | USA | – | – | NO | – | 16172 16221 16291 16300 | 16024-16569 | n.d. | – | – | HV4a1a5 | – | 200000 | This study
GP23 | America | Canada | French Canadian | – | NO | JN214423 | 16172 16221 16291 16300 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a5 | Complete genome | 200000 | This study
53G | Europe | Spain | Basque Country | – | YES | JN214394 | 16189 16221 16291 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a | Complete genome | 146 | This study; control region data already in Cerezo et al. (2010)
404 | Europe | Spain | Cantabria | Liébana | YES | JN214400 | 16213 16221 16291 | 16024-16569 | 73 263 309+C 315+C | 1-576 | – | HV4a1a2a | Complete genome | 135 | This study; control region data already in Álvarez-Iglesias et al. (2009)
34-1 | Europe | Spain | Cantabria | Liébana | YES | – | 16213 16221 16291 | 15997-16399 | n.d. | – | – | HV4a1a2a | RFLPs available | 72 | Maca-Meyer et al. (2003)
34-2 | Europe | Spain | Cantabria | Liébana | YES | – | 16213 16221 16291 | 15997-16399 | n.d. | – | – | HV4a1a2a | RFLPs available | 72 | Maca-Meyer et al. (2003)
V64Bas | Europe | Spain | Basque Country | Vizcaya | YES | GQ888729 | 16221 16241 16291 | 16024-16569 | 263 309+CC 315+C | 1-576 | – | HV4a1a | Complete genome | 113 | [NAME]. (2010)
GP19 | America | Canada | French Canadian | – | NO | JN214414 | 16221 16291 | 16024-16569 | 152 251 263 309+CC 315+C | 1-576 | – | HV4a1a4 | Complete genome | 200000 | This study
72 | America | Canada | Acadia | – | NO | – | 16221 16291 | 16069-16383 | 152 263 309+C 315+C | 58-370 | – | HV4a1a1 | – | 774 | Moreau et al. (2009)
534 | America | Canada | Gaspesians; French Canadian | – | NO | – | 16221 16291 | 16069-16383 | 152 263 309+C 315+C | 58-370 | – | HV4a1a1 | – | 774 | Moreau et al. (2009)
535 | America | Canada | Gaspesians; French Canadians | – | NO | – | 16221 16291 | 16069-16383 | 152 263 309+C 315+C | 58-370 | – | HV4a1a1 | – | 774 | Moreau et al. (2009)
735 | America | Canada | Loyalists; Canada | – | NO | – | 16221 16291 | 16069-16383 | 152 263 309+C 315+C | 58-370 | – | HV4a1a1 | – | 774 | Moreau et al. (2009)
24G | Europe | Spain | Basque Country | – | YES | JN214391 | 16221 16291 | 16024-16569 | 152 263 309+C 315+C | 1-576 | 16302 A-G; 309 lengh hetoroplasmy | HV4a1a1 | Complete genome | 146 | This study; control region data already in Cerezo et al. (2010)
GP6 | Europe | France | – | – | YES | JN214410 | 16221 16291 | 16024-16569 | 152 263 309+C 315+C | 1-576 | – | HV4a1a4 | Complete genome | 200000 | This study
GP7 | Europe | France | – | – | YES | JN214411 | 16221 16291 | 16024-16569 | 152 263 309+C 315+C | 1-576 | – | HV4a1a4 | Complete genome | 200000 | This study
GP11 | America | Canada | French Canadian | – | NO | JN214415 | 16221 16291 | 16024-16569 | 152 263 309+C 315+C | 1-576 | – | HV4a1a4 | Complete genome | 200000 | This study
GP13 | America | Canada | French Canadian | Prince Edward Island, Tignish | NO | JN214416 | 16221 16291 | 16024-16569 | 152 263 309+C 315+C | 1-576 | – | HV4a1a4 | Complete genome | 200000 | This study
GP14 | Europe | France | Southern | – | YES | JN214412 | 16221 16291 | 16024-16569 | 152 263 309+C 315+C | 1-576 | – | HV4a1a4 | Complete genome | 200000 | This study
GP27 | Europe | France | – | – | YES | JN214413 | 16221 16291 | 16024-16569 | 152 263 309+C 315+C | 1-576 | – | HV4a1a4 | Complete genome | 200000 | This study
109G | Europe | Spain | Basque Country | – | YES | JN214393 | 16221 16291 | 16024-16569 | 152 263 309+CC 315+C | 1-576 | 16302 G>A | HV4a1a1 | Complete genome | 146 | This study; control region data already in Cerezo et al. (2010)
73 | America | Canada | Acadia | – | NO | – | 16221 16291 | 16069-16383 | 152 263 315+C | 58-370 | – | HV4a1a1 | – | 774 | Moreau et al. (2009)
537 | America | Canada | Gaspesians; French Canadians | – | NO | – | 16221 16291 | 16069-16383 | 152 263 315+C | 58-370 | – | HV4a1a1 | – | 774 | Moreau et al. (2009)
GP35 | Europe | Ireland | – | Limerick | NO | JN214421 | 16221 16291 | 16024-16569 | 195 263 309+C 315+C | 1-576 | – | HV4a1a | Complete genome | 200000 | This study
1626 | Europe | Spain | Castilla León | Valladolid | YES | JN214408 | 16221 16291 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a | Complete genome | 2202 | This study
84G | Europe | Spain | Basque Country | – | YES | JN214396 | 16221 16291 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a | Complete genome | 146 | This study; control region data already in Cerezo et al. (2010)
GP15 | Europe | Denmark | – | – | NO | JN214422 | 16221 16291 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a | Complete genome | 200000 | This study
USA.CAU.000406 | America | USA | Caucasian | – | NO | – | 16221 16291 | 16024-16365 | 263 309+C 315+C | 73-340 | – | HV4a1a | – | 4839 | Monson et al. (2002)
GP26 | America | USA | Mississippi | Natchez | NO | JN214417 | 16221 16291 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a4 | Complete genome | 200000 | This study
159 | Europe | Spain | Aragón | [NAME] | YES | JN214407 | 16221 16291 | 16024-16569 | 263 309+C 315+C 523-524d | 1-576 | – | HV4a1a | Complete genome | 2202 | This study
2HL | Europe | Spain | Basque Country | – | YES | JN214395 | 16221 16291 | 16024-16569 | 263 309+CC 315+C | 1-576 | 309 lengh heteroplasmy | HV4a1a | Complete genome | 146 | This study; control region data already in Cerezo et al. (2010)
GP32 | Europe | France | – | Martinique | YES | JN214405 | 16221 16291 | 16024-16569 | 263 309+CC 315+C | 1-576 | – | HV4a1a | Complete genome | 200000 | This study
03B16202 | Europe | Spain | [NAME] | – | YES | HQ675034 | 16221 16291 | 16024-16569 | 263 309+CCC 315+C | 1-576 | – | HV4a1a3 | Complete genome | 11 | Seone et al. (2011)
2393Pot | Europe | Spain | Cantabria | Potes | YES | GQ888728 | 16221 16291 | 16024-16569 | 263 315+C | 1-576 | – | HV4a1a2 | Complete genome | 6 | [NAME]. (2010)
1754 | Europe | Spain | Navarra | – | YES | JN214409 | 16221 16291 | 16024-16569 | 263 315+C | 1-576 | – | HV4a1a | Complete genome | 2202 | This study
310 | Europe | Spain | Cantabria | Liébana | YES | JN214398 | 16221 16291 | 16024-16569 | 73 146 263 309+C 315+C | 1-576 | – | HV4a1a2a | Complete genome | 135 | This study; control region data already in Álvarez-Iglesias et al. (2009)
249 | Europe | Spain | Cantabria | Liébana | YES | JN214399 | 16221 16291 | 16024-16569 | 73 152 263 309+C 315+C | 1-576 | – | HV4a1a2a | Complete genome | 135 | This study; control region data already in Álvarez-Iglesias et al. (2009)
1912 | Europe | Spain | [NAME] | Guadalajara | YES | JN214404 | 16221 16291 | 16024-16569 | 73 263 309+C 315+C | 1-576 | – | Hv4a1a2a | Complete genome | 2202 | This study
3454 | Europe | Spain | Asturias | Asturias | YES | JN214403 | 16221 16291 | 16024-16569 | 73 263 309+C 315+C | 1-576 | – | Hv4a1a2a | Complete genome | 2202 | This study
– | Europe | Spain | Asturias | – | YES | – | 16221 16291 | 15997-16569 | 73 263 309+C 315+C | 1-408 | – | HV4a1a2a | RFLPs available | 76 | [NAME]. (2010)
GP3 | America | Canada | – | – | NO | JN214401 | 16221 16291 | 16024-16569 | 73 263 309+C 315+C | 1-576 | – | HV4a1a2a | Complete genome | 200000 | This study
GP18 | Europe | Spain | Asturias | Oviedo | YES | JN214402 | 16221 16291 | 16024-16569 | 73 263 309+C 315+C | 1-576 | 16126 T-C | HV4a1a2a | Complete genome | 200000 | This study
409 | Europe | Spain | Cantabria | Liébana | YES | JN214397 | 16221 16291 | 16024-16569 | 73 263 309+C 315+C | 1-576 | – | HV4a1a2a | Complete genome | 135 | This study; control region data already in Álvarez-Iglesias et al. (2009)
GRX280 | Europe | Spain | Asturias | – | YES | – | 16221 16291 | 16024-16365 | 73 263 315+C | 73-340 | – | HV4a1a | – | 312 | [NAME]. (2007)
29 | Europe | Spain | Cantabria | Liébana | YES | – | 16221 16291 | 15997-16399 | n.d. | – | – | HV4a1a | RFLPs available | 72 | Maca-Meyer et al. (2003)
57 | Europe | Spain | [NAME] | – | YES | – | 16221 16291 | 15997-16399 | n.d. | – | – | HV4a1a | RFLPs available | 43 | [NAME] (2003)
298 | Europe | Spain | Cantabria | Liébana | YES | – | 16221 16291 | 16024-16400 | n.d. | – | – | HV4a1a | mtSNPs available | 135 | [NAME] et al. (2009)
GP2 | America | USA | New Jersey | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
GP4 | America | USA | Ashton Under Lyne, Lancashire | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
GP8 | America | Canada | – | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
GP16 | America | USA | – | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
GP17 | America | USA | – | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
GP20 | Europe | Ireland | Belfast | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
GP21 | America | USA | Arkansas | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
GP22 | Europe | Norway | – | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
GP28 | America | USA | – | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
GP33 | America | USA | – | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | 16093 T-C | HV4a1a | – | 200000 | This study
GP34 | Middle East | Afghanistan | – | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
GP38 | America | USA | Natchez | – | NO | – | 16221 16291 | 16024-16569 | n.d. | – | – | HV4a1a | – | 200000 | This study
G-63 | Europe | Spain | Basque Country | – | YES | – | 16221 16291 | 16090-16365 | n.d. | – | – | HV4a1a | – | 48 | [NAME] et [NAME]. (1996)
G-72 | Europe | Spain | Basque Country | – | YES | – | 16221 16291 | 16090-16365 | n.d. | – | – | HV4a1a | – | 48 | [NAME] et [NAME]. (1996)
400 | America | USA | North America | – | NO | – | 16221 16291 | n.a. | 263 | n.a. | – | HV4a1a | – | 543 | Parsons et al. Armed Forces Institute of Phatology
065G | Europe | Spain | Basque Country | – | YES | JN214392 | 16221 16291 16302 | 16024-16569 | 152 263 309+CC 315+C | 1-576 | 309 lengh hetoroplasmy | HV4a1a1 | Complete genome | 146 | This study; control region data already in Cerezo et al. (2010)
GP5 | Europe | Italy | Potenza | Melfi | NO | JN214420 | 16221 16291 16311 16355 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a4a | Complete genome | 200000 | This study
CAD942 | Europe | Italy | Campania | Avellino | NO | JN214418 | 16221 16291 16355 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a4a | Complete genome | [NAME] | This study
GP10 | Europe | Italy | Avellino | [NAME] | NO | JN214419 | 16221 16291 16355 | 16024-16569 | 263 309+CC 315+C | 1-576 | – | HV4a1a4a | Complete genome | 200000 | This study
946 | Europe | Spain | Castilla León | Segovia | YES | JN214406 | 16221 16291 16399 | 16024-16569 | 263 309+C 315+C | 1-576 | – | HV4a1a | Complete genome | 2202 | This study
[1]: haplogroup classification to the maximun level of resolution according to the control and coding region information available
[2]: Coding region information supporting compatibility with HV4 status
References
[NAME], Mosquera-Miguel A, Cerezo M, Quintáns B, [NAME], Cuscó I, [NAME], [NAME] O, Pérez-Jurado L, Carracedo Á, [NAME] (2009) New population and phylogenetic features of the internal variation within mitochondrial DNA macro-haplogroup R0. [NAME] ONE 4: e5112
[NAME], Johnson DE, [NAME], Martínez-espin E, [NAME], [NAME], Wilson MR, Budowle B (2007) Characterization of human control region sequences for Spanish individuals in a forensic mtDNA data set. Legal Med 9: 293-304
Cerezo M, Bandelt H-J, [NAME] I, [NAME], [NAME], [NAME], [NAME] A, Salas A (2009) High mitochondrial DNA stability in B-cell chronic lymphocytic leukemia. [NAME] One 4: e7902
[NAME], [NAME] R, Larruga JM, [NAME], Yurrebaso I, [NAME] VM, [NAME] (2010) Using mitochondrial DNA to test the hypothesis of a European post-glacial human recolonization from the Franco-Cantabrian refuge. Heredity; in press
[NAME], [NAME], [NAME], Maca-Meyer N, [NAME], [NAME] VM (2003) Mitochondrial DNA affinities at the Atlantic fringe of Europe. Am J Phys Anthropol 120: 391-404
Maca-Meyer N, Sánchez-Velasco P, [NAME], Larruga JM, [NAME], Oterino A, Leyva-Cobian F (2003) Y chromosome and mitochondrial DNA characterization of Pasiegos, a human isolate from Cantabria (Spain). [NAME] 67: 329-39
[NAME], [NAME], Wilson MR, [NAME], Budowle B (2002) The mtDNA Population Database: an integrated software and database resource for forensic comparison. Forensic [NAME] 4: no 2
[NAME], Vezina H, [NAME], Hamon R, de Knijff P, Sinnett D, Labuda D (2009) Genetic heterogeneity in regional populations of Quebec--parental lineages in the Gaspe Peninsula. Am J Phys Anthropol 139: 512-22
[NAME], Côrte-Real H, Forster P, Macaulay V, Wilkinson-Herbots H, Demaine A, [NAME], Hedges R, Bandelt H-J, Sykes B (1996) Paleolithic and neolithic lineages in the European mitochondrial gene pool. Am. [NAME]. [NAME]. 59: 185-203
Seoane, M., A., M.-M., [NAME], T., [NAME], M., Salas, A., and J.A., C. (2011). The mitochondrial genome is a "genetic sanctuary" during the oncogenic process. [NAME] One; in press.