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Unnamed: 0 | 2006 CDC Treatment Summaries for Chlamydia, Gonorrhea, Syphilis, | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5
 | and Outpatient Oral Regimens for [NAME] Disease¹
 | A Quick Reference Guide from the Wyoming Department of Health
Infection | Recommended Rx |  | Dose/Route |  | Alternatives/Notes
Chlamydia
Chlamydia in adults, | [NAME] (Zithromax)  or |  | 1 g orally in a single dose |  | Erythromycin base 500 mg orally QID x 7 days or
adolescents, and children | Doxycycline |  | 100 mg orally BID x 7 days |  | Erythromycin ethylsuccinate (EES) 800 mg orally QID x 7 days or
aged ≥8 years |  |  |  |  | Ofloxacin 300 mg orally BID x 7 days or
 |  |  |  |  | Levofloxacin 500 mg orally once daily x 7 days
Chlamydia in pregnancy | [NAME] or |  | 1 g orally in a single dose |  | Erythromycin base 500 mg orally QID x 7 days or
 | Amoxicillin |  | 500 mg orally TID x 7 days |  | Erythromycin base 250 mg orally QID x 14 days or
 |  |  |  |  | EES 800 mg orally QID x 7 days or
 |  |  |  |  | EES 400 mg orally QID x 14 days
Chlamydia in infants-- | Erythromycin base or |  | 50 mg/kg/day orally divided into |  | Topical antibiotic therapy alone is inadequate for the treatment of chlamydial
opthalmia or pneumonia | Erythromycin ethylsuccinate² |  | 4 doses daily x 14 days |  | infections and is unnecessary when systemic treatment is administered².
[NAME]
Uncomplicated infections | Ceftriaxone ([NAME])  or |  | 125 mg IM in a single dose |  | Cephalosporin 500 mg IM or
of the cervix, urethra and | Cefixime (Suprax) |  | 400 mg orally in a single dose |  | Cefoxitin 2 g IM with 1 g probenecid orally or Cefotaxime (Claforan) 500 mg IM
rectum in adults, | Plus, if chlamydia is not ruled out:
adolescents, and children | [NAME] or |  | 1 g orally in a single dose |  | [NAME] or doxycyclin should be administered
who weigh >45 kg | Doxycycline |  | 100 mg orally BID x 7 days |  | if chamydial infection has not been ruled out.
Uncomplicated infections | Ceftriaxone ([NAME]) |  | 125 mg IM in a single dose |  | Although chlamydial coinfection of the pharynx is unusual,
of the pharynx | Plus, if chlamydia is not ruled out: |  |  |  | coinfection at gential sites sometimes occurs.  Therefore,
 | [NAME] or |  | 1 g orally in a single dose |  | treatment for both gonorrhea and chlamydia is recommended.
 | Doxycycline |  | 100 mg orally BID x 7 days
Gonorrhea in pregnancy | Pregnant women should not be treated with tetracyclines.  A recommended or alternate cephalosporin should be used.
[NAME] in infants-- | Ceftriaxone (Rocephin) |  | 25-50 mg/kg IV or IM in a single |  | Topical antibiotic therapy alone is inadequate and is unnecessary if systemic
ophthalmia neonatorum |  |  | dose, not to exceed 125 mg |  | treatment is administered.  Infants with gonococcal opthalmia should be
 |  |  |  |  | hospitalized and evaluated for signs of disseminated infection.
Infection | Recommended Rx |  | Dose/Route |  | Alternatives/Notes
[NAME] Disease
Oral treatment | Ceftriaxone ([NAME])  or |  | 250 mg IM in a single dose |  | For women with PID of mild or moderate severity, parenteral an oral therapy
 | Cefoxitin (Mephoxin) with |  | 2 g IM in a single dose |  | appear to have similar clinical efficacy.  The decision of whether hospitalization
 | Probenecid (Benemid)  or |  | 1 g orally administered |  | should be based on the discretion of the health-care provider.
 | other parenteral 3rd generation |  | concurrently in a single dose |  | Patients who do not respond well to oral therapy within 72 hours should be
 | cephalosporin (e.g. ceftizoxime or |  |  |  | reevaluated to confirm the diagnosis and should be administered parenteral
 | cefotaxime) |  |  |  | therapy on an outpatient or inpatient basis.
 | PLUS
 | Doxycycline with or without |  | 100 mg orally BID x 14 days |  | Doxycycline should be included with any
 | Metronidazole |  | 500 mg orally BID x 14 days |  | third generation cephalosporin.
Syphilis
Primary, secondary, or early | Benzathine penicillin G |  | 2.4 million units IM in a single dose |  | Early latent syphilis is latent syphilis of less than
latent syphilis in adults |  |  |  |  | one-year duration.
Primary, secondary, or early | Benzathine penicillin G |  | 50,000 units/kg IM, up to the adult dose
latent syphilis in children |  |  | of 2.4 million units in a single dose
Early syphilis in non-pregnant | Doxycycline or |  | 100 mg orally BID x 14 days |  | Limited studies suggest that ceftriaxone is effective for treating early syphilis,
adults & adolescents allergic | Tetracycline |  | 500 mg orally QID x 14 days |  | but the optimal dose and duration have not been defined.  Some specialists
to penicillin |  |  |  |  | recommend 1 g daily either IM or IV for 8-10 days.  Preliminary data indicate
 |  |  |  |  | that azithromycin may be effective in a single dose of 2g.  Close follow-up of
 |  |  |  |  | persons receiving alternative therapies is essential.
Early syphilis in pregnancy | Benzathine penicillin G |  | 2.4 million units IM in a single dose |  | Pregnant women who are allergic to penicillin should be
 |  |  |  |  | desensitized and treated with penicillin.
Late latent syphilis or latent | Benzathine penicillin G |  | 7.2 million units total, administered |  | For non-pregnant persons allergic to penicillin, doxycycline 100
syphilis of unknown duration |  |  | as 3 doses of 2.4 million units IM |  | mg orally BID should be administered for 28 days or tetracycline
in adults |  |  | each at 1-week intervals |  | 500 mg orally QID x 28 days.
Late latent syphilis or latent | Benzathine penicillin G |  | 50,000 units/kg IM, up to the adult
syphilis of unknown duration |  |  | dose of 2.4 million units, administered
in children |  |  | as 3 doses at 1-week intervals (total
 |  |  | 150,000 units/kg up to the adult
 |  |  | total dose of 7.2 million units
[NAME] | Consult the 2006 STD Treatment Guidelines (MMWR Vol 55, No. RR-11) or http://www.cdc.gov/std/treatment/
¹ Centers for Disease Control and Prevention.  Sexually Transmitted Diseases Treatment Guidelines, 2006.  MMWR 2006;55(No. RR-11).
²An association between oral erythromycin and infantile hypertrophic pyloric stenosis has been reported in infants <6 weeks who were treated with this drug.  Infants treated with
erythromycin should be followed for signs and symtoms of idiopathic hypertrophic pyloric stenosis (IHPS).