Spreadsheet: ad7a6603-3753-4779-92d7-86b808366c4a
Sheet: Sheet1

Table S11 - List of  58 genes differentially expressed in common between schistosomula and adult paired worms  treated with TNF-alpha | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7
Probe | Contig | Sequence | Class | Annotation | Schistosomula-TNF response_1h | Adult-TNF response_1h | Adult-TNF response_24h
Q2_P29512 | C903723.1 | TGATCCTAGAACTGGTAAATATATGGCATGTTGTTTATTATATCGTGGTGATGTTGTCCC | Sm_Orth_inOther_sp | alpha-tubulin [Schistosoma mansoni] ||PREDICTED: similar to tubulin  alpha 2  tubulin alpha 2 [Gallus gallus] ||alpha tubulin [Gallus gallus] ||Tubulin alpha-5 chain ||tubulin alpha-5 chain - chicken | UP | UP | DOWN
Q2_P01206 | C802804.1 | TGGCGGTGTGACTAGAATGACTATATCATTAGTTGTAGTTATGCTTGAATTAACTGGCGG | Sm_Orth_inOther_sp | chloride channel CLCN5 [Cavia porcellus] ||outwardly rectifying chloride channel [Sus scrofa] gb|AAG29104.1| outwardly rectifying chloride channel [Sus scrofa] ||chloride channel CLC-5 [Oryctolagus cuniculus] ||unnamed protein product [Mus musculus] ||unnamed protein product [Mus musculus] | UP | DOWN | UP
Q2_P33064 | C910073.1 | TATGGATGGAGGGACTTTTACGATTAGCAACGGTGGTGTTTTTGGCTCATTATTTGGTAC | Sm_Orth_inOther_sp | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex  mitochondrial precursor (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex) (E2) ([NAME]) gb|AAC59779.1| dihydrolipoamide succinyltransferase ||PREDICTED: similar to dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) isoform 1 [Canis familiaris] ||PREDICTED: similar to dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) isoform 5 [Canis familiaris] ||PREDICTED: similar to dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) isoform 4 [Canis familiaris] ||PREDICTED: similar to dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) isoform 3 [Canis familiaris] | UP | DOWN | DOWN
Q2_P13509 | C910559.1 | ACCCGCACTATCATCCTATGTGGTTTCCCGAATGTTGGAAAGTCGAGCTTTATCAACAAA | Sm_Orth_inOther_sp | GTPBP4 protein [Homo sapiens] ||unnamed protein product [Macaca fascicularis] ||G protein-binding protein CRFG variant [Homo sapiens] ||G protein-binding protein CRFG [Homo sapiens] emb|CAI13664.1| GTP binding protein 4 [Homo sapiens] gb|AAH38975.1| G protein-binding protein CRFG [Homo sapiens] gb|AAK13444.1| G protein-binding protein CRFG [Homo sapiens] sp|Q9BZE4|NOG1_HUMAN Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB) ||unnamed protein product [Homo sapiens] | UP | UP | DOWN
Q2_P05755 | C810508.1 | CTTGAATATCAGGTTTTCCGTTTTTGTTTTCACCCGATGTACTTTGGTAACTGCATAATT | Sm_Orth_inOther_sp | hypothetical protein in Macaca fascicularis  similar to GenBank Accession Number AB071068 hypothetical protein in Macaca fascicularis [Schistosoma japonicum] ||SJCHGC02038 protein [Schistosoma japonicum] ||unknown [Schistosoma japonicum] ||Hypothetical gene supported by BC052750 [Homo sapiens] ref|NP_940961.1| hypothetical protein LOC375307 [Homo sapiens] ||hypothetical protein [[NAME] fascicularis] | DOWN | DOWN | DOWN
Q2_P07640 | C813179.1 | TAACTCCACTTCTATGATCTCAAGCGTATTCGGACGTTGATTTAATTCGGGGACGTCAGT | Sm_Orth_inOther_sp | mKIAA1748 protein [Mus musculus] [NAME] protein [Homo sapiens] ||PREDICTED: similar to Zinc finger DHHC domain containing protein 5 (Zinc finger protein 375) isoform 1 [Canis familiaris] [NAME] finger  DHHC domain containing 5 [Homo sapiens] dbj|BAB14420.1| unnamed protein product [Homo sapiens] sp|Q9C0B5|ZDHC5_HUMAN Zinc finger DHHC domain containing protein 5 (Zinc finger protein 375) ||zinc finger  DHHC domain containing 5 [Mus musculus] gb|AAH65155.1| Zinc finger  DHHC domain containing 5 [Mus musculus] dbj|BAC38513.1| unnamed protein product [Mus musculus] gb|AAH20051.1| Zinc finger  DHHC domain containing 5 [Mus musculus] sp|Q8VDZ4|ZDHC5_MOUSE Zinc finger DHHC domain containing protein 5 | UP | DOWN | UP
Q2_P03921 | C807377.1 | ACAGTGTTGGTAATAGTACCAGTGAATACAGTACACGTCTAGTGAAATCTTCTTGGCTAA | Sm_noMatches_Gb_bothSt | none | UP | DOWN | DOWN
[NAME] | C810949.1 | GTGAAAACTTTCTGTACCTTTTTCTTCGCATTATATCCGTGAGTGTTAATAACCGAATGG | Sm_noMatches_Gb_bothSt | none | DOWN | UP | UP
Q2_P07379 | C812854.1 | CAAAGTATTGTTTGCATATTGTACTTGTTACCGGTCGGGAAAATATAATTTGCTGAGGAA | Sm_noMatches_Gb_bothSt | none | DOWN | UP | UP
Q2_P12663 | C909013.1 | CACTGGTTACTTCATCAACTTACGTCTATCTGAACCCAACTAATATTAAAAGATATCTGG | Sm_noMatches_Gb_bothSt | none | DOWN | UP | UP
Q2_P15986 | C916172.1 | GCCGGCACACGCACACACATTCAAATAATACATACAATCTTGTAGATAATTATTATTTGG | Sm_noMatches_Gb_bothSt | none | DOWN | UP | UP
Q2_P17265 | C918740.1 | CACCATTATGATTAACGATTTATCCAAGGGTTGTATTACTAGTCACTATGGTGATGATGA | Sm_noMatches_Gb_bothSt | none | DOWN | UP | UP
Q2_P31274 | C906665.1 | CTGGACTAACCGCTTTAAGTACTATACTTCATTCATTAATTCCATTAATGCGTTTACCAG | Sm_noMatches_Gb_bothSt | none | UP | UP | UP
Q2_P06219 | C811018.1 | GGTTCTTCTTTACATTGTTTTCCTAAACAGTTTTTGACTCTTCATTTGTGCTGTCCTAAC | Sm_noMatches_Gb_bothSt | none | DOWN | UP | UP
Q2_P04672 | C808600.1 | ACGTTATACCGACACTAATCCTCTGCATATAATTTTGAAGAGCTACGTTATACCGACACT | Sm_noMatches_Gb_bothSt | none | UP | DOWN | UP
Q2_P05263 | C809701.1 | TTCCCCAAGTAGTAGTCCCCAAATCCTTCTGAATAAACATACTGATTAGTATCTGTCCTG | Sm_noMatches_Gb_bothSt | none | DOWN | UP | DOWN
Q2_P05990 | C810766.1 | TCCCAGAAGATATGCTTCCATCATCCTCTGATAGTTCTGATACAGAAAGTGAATGTATAT | Sm_noMatches_Gb_singleSt | none | DOWN | UP | DOWN
Q2_P06017 | C810796.1 | GGATGATTTTGTTCTCATTCTATCAGTAATTCATTTCTCTGATGAGTCCACAAATTGTGC | Sm_noMatches_Gb_bothSt | none | DOWN | DOWN | UP
Q2_P07411 | C812887.1 | CGTTGGCATGAAAACGTAACACATTTTACATATGTGTCAGTATTGGGTTATATTGCTTTC | Sm_noMatches_Gb_bothSt | none | DOWN | DOWN | UP
Q2_P16130 | C916457.1 | CCGTTTTTCGTTGTCATATTCAATGCTTCCACTTTTCTTCTTGTCTCTATCTCTTTGTTA | Sm_noMatches_Gb_bothSt | none | DOWN | DOWN | UP
Q2_P16471 | C917150.1 | ACTACTTTGGTGTCTCTGACAACCAGGAAGGGGAAGGGTGCTGTTGTGCGGACGTCGTTG | Sm_noMatches_Gb_bothSt | none | UP | UP | DOWN
Q2_P16848 | C917857.1 | TAAATATCGACTCATACTTAGTTAAGTGGAGTTGGCTCACACGCCTTCTCCATTGCGCGT | Sm_noMatches_Gb_bothSt | none | DOWN | UP | DOWN
Q2_P17406 | C919287.1 | GCTTACACGTCGTATTGTATTGTTCACTTTCGATAAATACTGGTGTTTCACATCTATACA | Sm_noMatches_Gb_bothSt | none | DOWN | DOWN | UP
Q2_P17631 | C920097.1 | GAGAGCTTACCACTTCCTCCTGACGAATGGATGCCGTTCTGCGGTAGTTCAAGTGATTTA | Sm_noMatches_Gb_bothSt | none | DOWN | UP | DOWN
Q2_P17986 | C800118.1 | GTTGGCCATTTCATCAATCTCTATGATAGTTATTGGACTGATCAATGGTCATTTAAGAAG | Sm_noMatches_Gb_bothSt | none | UP | UP | DOWN
Q2_P18028 | C800163.1 | GGAGCGGTAGCAGCATACGTTTTTTACCATTTCTATGGTTAAAATATATGAAGAGGATTT | Sm_noMatches_Gb_bothSt | none | UP | UP | DOWN
Q2_P18556 | C800792.1 | AATGGCTTAGTTGAACAATTGGATCGCCTGGAACTCGAAGCAGATATTACTTTTCCTCAT | Sm_noMatches_Gb_bothSt | none | DOWN | UP | DOWN
Q2_P19016 | C801623.1 | GTTGGCTCAATTGGTAGTGTTTTTGTAATACGTCGAATACAACGTAGACATTATCAAAGA | Sm_noMatches_Gb_bothSt | none | UP | UP | DOWN
Q2_P25525 | C810391.1 | GGACGATGCTTATCGACAATTACAACATTTCTAATGGGGGATATAAAGTTGTTTTCTTTG | Sm_noMatches_Gb_bothSt | none | DOWN | DOWN | UP
Q2_P27356 | C813428.1 | GATGCTTCTTGGAATATGGACAATCTGAAGAAGTTGGTTTTTCCTGGATAAAATACAGAA | Sm_noMatches_Gb_bothSt | none | UP | UP | DOWN
Q2_P29437 | C903617.1 | [NAME] | Sm_noMatches_Gb_bothSt | none | UP | UP | DOWN
[NAME] | C915490.1 | TCGTGTAGGACAATGCATAACCTTTTGTTTCATCTCGCCTGTTTGCAATGCTACGTCAAA | Sm_noMatches_Gb_bothSt | none | DOWN | UP | DOWN
Q2_P36234 | C916073.1 | CACAAGGTCGTCTTACGTCTTGGTTTTATCAAGCTGATGCTGATCCTTTAATGCCTAAAG | Sm_noMatches_Gb_bothSt | none | DOWN | UP | DOWN
Q2_P36470 | C916644.1 | AGCTGTTGAAGCCATATTGCGTCGTTGTTCACAAGCGCAATTGGTTTCTAAGTATAAGAT | Sm_noMatches_Gb_bothSt | none | DOWN | UP | DOWN
Q2_P38314 | C921103.1 | TGCTATATGGATAAGAACCCAGTTTCCCACAGACAAACCATTATTTGTCAGTCTTCTTCC | Sm_noMatches_Gb_bothSt | none | DOWN | UP | DOWN
Q2_P38616 | JAP08785.C | GTCTGGTTCAACGCGAAGTGATCATGTACCGATACATTTACGTGGAAGCTTAGTCAATCA | Sm_newGenes_Orth_onlyJapon | none | UP | UP | DOWN
Q2_P21551 | C805025.1 | CTACCGTATGAGGGGTGCACTTACGACAAAGCAATTGACCTCTATCAGACTCTTGACCAA | Sm_Orth_inOther_sp | PREDICTED: similar to CG6884-PA [[NAME] rerio] ||CG6884-PA [Drosophila melanogaster] ref|NP_649057.1| CG6884-PA [Drosophila melanogaster] gb|AAM27478.1| GH01072p [Drosophila melanogaster] ||GA19929-PA [Drosophila pseudoobscura] | DOWN | UP | DOWN
Q2_P32385 | C908791.1 | AAATGGCTGATTTAAATAAAATTATCCGAGAATTATGGCGCAGTACATACCGTGGCAATG | Sm_Orth_inOther_sp | PREDICTED: similar to DNA repair protein RAD50 (mRad50) [Strongylocentrotus purpuratus] ||PREDICTED: similar to DNA repair protein RAD50 (mRad50) [Strongylocentrotus purpuratus] ||RAD50 homolog (S. cerevisiae) [Mus musculus] ||RAD50 homolog isoform 2 [Homo sapiens] gb|AAD50326.1| truncated RAD50 protein [Homo sapiens] ||RAD50 homolog isoform 1 [Homo sapiens] sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 (hRAD50) gb|AAD50325.1| RAD50-2 protein [Homo sapiens] gb|AAB07119.1| Rad50 [Homo sapiens] | UP | DOWN | UP
Q2_P08263 | C901496.1 | [NAME] | Sm_Orth_inOther_sp | PREDICTED: similar to Est1p-like protein A [[NAME] taurus] ||Est1p-like protein A [Homo sapiens] gb|AAN46114.1| telomerase subunit EST1A [Homo sapiens] sp|Q86US8|EST1A_HUMAN Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A) ||PREDICTED: similar to Est1p-like protein A [Canis familiaris] ||hypothetical protein [Homo sapiens] ||C17orf31 protein [Homo sapiens] | UP | UP | UP
Q2_P35970 | C915732.1 | CGCGGAAAGTGTAGATTCTGGTCATCAGAATCTTGATGTTAATAAACATTGATCAATAGT | Sm_Orth_inOther_sp | PREDICTED: similar to LIM domain kinase 1 isoform 1 [Canis familiaris] ||unknown [Homo sapiens] ||LIM domain kinase 1 isoform 1 [Homo sapiens] dbj|BAA05371.1| LIM kinase [Homo sapiens] ||LIM domain kinase 1 [synthetic construct] ||unnamed protein product [Mus musculus] | DOWN | UP | DOWN
Q2_P28092 | C901681.1 | AAGTACGCGTTTCTATTTATGCATGCATATGACACTGAGGAGACGTTTCGGCAATCTTGT | Sm_Orth_inOther_sp | PREDICTED: similar to Protein C14orf130 isoform 3 [Canis familiaris] ||PREDICTED: similar to Protein C14orf130 isoform 5 [Canis familiaris] ||PREDICTED: similar to Protein C14orf130 isoform 4 [Canis familiaris] ||PREDICTED: similar to Protein C14orf130 isoform 1 [Canis familiaris] ||hypothetical protein LOC66622 [Mus musculus] dbj|BAE29217.1| unnamed protein product [Mus musculus] dbj|BAC40212.1| unnamed protein product [Mus musculus] gb|AAH94423.1| Hypothetical protein LOC66622 [Mus musculus] sp|Q8BU04|CN130_MOUSE Protein C14orf130 homolog | UP | UP | DOWN
Q2_P26333 | C811811.1 | CTCGCTTAGGCCATCACTTTCTGTTCTTATGTGACTATAATTCAGTGAATAAGAAAATAC | Sm_Orth_inOther_sp | similar to GenBank Accession Number AK015888 EG:22E5 [Schistosoma japonicum] ||SJCHGC02197 protein [Schistosoma japonicum] ||SJCHGC03993 protein [Schistosoma japonicum] ||hypothetical protein LOC67171 isoform 2 [Mus musculus] dbj|BAE43014.1| unnamed protein product [Mus musculus] dbj|BAB26598.1| unnamed protein product [Mus musculus] dbj|BAC35162.1| unnamed protein product [Mus musculus] dbj|BAB27990.1| unnamed protein product [Mus musculus] ||PREDICTED: similar to RIKEN cDNA 2610318G18 [Gallus gallus] | DOWN | DOWN | DOWN
Q2_P24786 | C809332.1 | CAGTATGATGTTGTTAATTCGAAATTGGAGCCAAATTCCAAGATTAACAACTGATGTCGT | Sm_Schisto_Orth_only | SJCHGC01429 protein [Schistosoma japonicum] | DOWN | UP | DOWN
Q2_P26637 | C812251.1 | GATGTGGTAGTAAAGAAAAGATCAATGGCAGGATTACCATCTGGTTCAATTCAAAAGATA | Sm_Orth_inOther_sp | SJCHGC02328 protein [Schistosoma japonicum] ||IR3 [Schistosoma japonicum] ||ENSANGP00000023276 [Anopheles gambiae str. PEST] ref|XP_313754.2| ENSANGP00000023276 [Anopheles gambiae str. PEST] ||ENSANGP00000003864 [Anopheles gambiae str. PEST] ref|XP_313753.2| ENSANGP00000003864 [Anopheles gambiae str. PEST] ||SUMO-1 activating enzyme subunit 1 [[NAME] tropicalis] | UP | UP | UP
Q2_P12507 | C908665.1 | [NAME] | Sm_Schisto_Orth_only | SJCHGC03042 protein [Schistosoma japonicum] | DOWN | UP | DOWN
Q2_P24098 | C808460.1 | GAGGGTGGCTTGGGTTGTCCAGTACCTGATGAATGGCTTACCAGCGGTGCTTTTCTAACA | Sm_Schisto_Orth_only | SJCHGC04365 protein [Schistosoma japonicum] | UP | UP | UP
Q2_P23785 | C808053.1 | GTTGCTGGATGCGAAGATGGAATATTCTCATGGACATTGAAAGATTTTCGTAAAGAAAAA | Sm_Orth_inOther_sp | SJCHGC04689 protein [Schistosoma japonicum] ||PREDICTED: hypothetical protein XP_783216 [Strongylocentrotus purpuratus] ||MGC82133 protein [[NAME] laevis] ||PREDICTED: similar to RIKEN cDNA 1200011O22 [Gallus gallus] ||hypothetical protein LOC71735 [Mus musculus] dbj|BAB23500.1| unnamed protein product [Mus musculus] | UP | DOWN | UP
Q2_P16059 | C916325.1 | GTTCCAGGTTTTTTACTTCGTCAGCCTTAAGTACAAATCTTCGAAATAAAACGATATCCT | Sm_Orth_inOther_sp | SJCHGC06204 protein [Schistosoma japonicum] ||RE29270p [Drosophila melanogaster] ||CG4153-PA [Drosophila melanogaster] ref|NP_524043.1| CG4153-PA [Drosophila melanogaster] sp|P41375|IF2B_DROME Eukaryotic translation initiation factor 2 beta subunit (eIF-2-beta) gb|AAA28504.1| eIF-2 beta-subunit ||ENSANGP00000016768 [Anopheles gambiae str. PEST] ref|XP_308567.2| ENSANGP00000016768 [Anopheles gambiae str. PEST] ||Hypothetical protein CBG08214 [Caenorhabditis briggsae] | DOWN | UP | UP
Q2_P41338 | JAP10937.C | GTGAACTGTTCCCGTTTTGACAGTAATGATGCGTTAGATTATAGGAATTCAGTTTTCATT | Sm_newGenes_Orth_onlyJapon | SJCHGC06445 protein [Schistosoma japonicum] | UP | UP | DOWN
Q2_P19789 | C802596.1 | ATCAACTTCTTATGACCCAAACATCCACACACCCGTTCACTTGTCTACTTTTGATTTTTT | Sm_Schisto_Orth_only | SJCHGC06587 protein [Schistosoma japonicum] | DOWN | UP | UP
[NAME] | C806349.1 | AAGTTCAAGAGTCCTTAATTCGATTCTTGGGTCTGTTCAGCCTGTCCAATACTTATTTCC | Sm_Schisto_Orth_only | SJCHGC07231 protein [Schistosoma japonicum] | UP | UP | DOWN
Q2_P22035 | C805712.1 | TCATTTCCTACTACTGATAATAGTGTGAAACAGTGCAGTGTTGTCGCTGAAGATATTAAA | Sm_Schisto_Orth_only | SJCHGC07955 protein [Schistosoma japonicum] | DOWN | UP | DOWN
[NAME] | C812187.1 | TACGGAAAAATGGATCAGCTCGACCATTCAATGATGTACACAAAGAAGTTGCAGAATTGA | Sm_Orth_inOther_sp | SJCHGC08254 protein [Schistosoma japonicum] ||PREDICTED: similar to XPMC2 prevents mitotic catastrophe 2 homolog [[NAME] rerio] ||XPMC2 prevents mitotic catastrophe 2 homolog [[NAME] tropicalis] ref|NP_001006868.1| XPMC2 prevents mitotic catastrophe 2 homolog [[NAME] tropicalis] sp|Q6DEW6|XPMC2_XENTR Probable exonuclease [NAME] (Prevents mitotic catastrophe 2 protein) ||PREDICTED: similar to XPMC2 prevents mitotic catastrophe 2 homolog [Strongylocentrotus purpuratus] ||XPMC2 protein | UP | UP | DOWN
Q2_P40788 | JAP09250.S | ACAAGCTATTGAGAAAGTGTCGTCTTGTGAACCCCGTTCACTAAAAATTGTAAAAGAATA | Sm_newGenes_Orth_onlyJapon | SJCHGC09725 protein [Schistosoma japonicum] | DOWN | UP | UP
Q2_P38969 | JAP09250.S | ACAAGCTATTGAGAAAGTGTCGTCTTGTGAACCCCGTTCACTAAAAATTGTAAAAGAATA | Sm_newGenes_Orth_onlyJapon | SJCHGC09725 protein [Schistosoma japonicum] | DOWN | UP | UP
Q2_P06108 | C810894.1 | GGTCATTCAATAACTGATTCTACCTGTACCATCTCTTAAGTTTTACATTGTTGTTTGAGC | Sm_Orth_inOther_sp | unknown [Schistosoma japonicum] ||SJCHGC01358 protein [Schistosoma japonicum] ||MGC83221 protein [[NAME] laevis] ||PREDICTED: similar to toll interacting protein [Strongylocentrotus purpuratus] ||hypothetical protein LOC336876 [[NAME] rerio] gb|AAH66544.1| Unknown (protein for MGC:76985) [[NAME] rerio] | DOWN | DOWN | UP
Q2_P00066 | C800187.1 | CAGGCTTTTCTCAATACCTAAATTGCTGAGTATTGCTTCTCAAAAGGAGAGTATTATTAC | Sm_Orth_inOther_sp | unknown [Schistosoma mansoni] ||SJCHGC03840 protein [Schistosoma japonicum] ||SJCHGC02755 protein [Schistosoma japonicum] ||hypothetical protein DDB0205464 [Dictyostelium discoideum] gb|EAL68399.1| hypothetical protein DDB0205464 [Dictyostelium discoideum] ||proteoglycan 4 [Homo sapiens] emb|CAC36090.1| proteoglycan 4 [Homo sapiens] | UP | UP | DOWN
Q2_P25591 | C810559.1 | CGCAGATTTTGCTGTATCTTACACAGGCCGAGAAGATTTCTTAATATACTGATTTTATAC | Sm_Orth_inOther_sp | unnamed protein product [Tetraodon nigroviridis] ||hypothetical protein  conserved [Trypanosoma cruzi] gb|EAN96957.1| hypothetical protein  conserved [Trypanosoma cruzi] ||PREDICTED: similar to establishment of cohesion 1 homolog 1 [[NAME] rerio] ||hypothetical protein AN2758.2 [Aspergillus nidulans FGSC A4] gb|EAA63192.1| hypothetical protein AN2758.2 [Aspergillus nidulans FGSC A4] | DOWN | UP | DOWN