Spreadsheet: c3c001a3-2b2c-46b8-967f-ead8feb23a8d
Sheet: Sheet1

Test Referenced | Entry Type | Mayo ID | Description | Reporting Description | Method | Collection Container | Temperature | Stability | [NAME] | Unit of Measure | [NAME] | Minimum Volume | Reject Due To | Reference Values | Days/Times Performed | Analytic Time | Maximum Lab Time | CPT Units | CPT Code | LOINC® Code | LOINC® Attributes | Always Performed | Orderable Separately | Performing Location
CMVC8 | Test | CMVC8 | Cytomegalovirus (CMV) CD8 T-Cell Immune Competence, Quantitative Assessment by Flow Cytometry | [NAME] QN by Flow Cytometry | Flow Cytometry |  |  |  |  |  | It is recommended that specimens arrive within 24 hours of draw. Specimens are required to be received in the laboratory on weekdays and by 4 p.m. on Friday. No weekend processing. Draw and package specimen as close to shipping time as possible.   Container/Tube: Green top (sodium heparin) [NAME]: 20 mL Collection Instructions: Ship specimen overnight in an [NAME] Specimens Only (Supply T668). Additional Information: 1. Ordering physician's name and phone number are required. 2. Patient must be cytomegalovirus (CMV)-seropositive and have 1 or more of the 5 major histocompatibility complex (MHC) alleles: [NAME], A2, B7, B8, or B35. (Suggested assay for HLA typing is SSO1 / HLA Class I Molecular Phenotype, Blood.) 3. For serial monitoring, we recommend that specimen draws be performed at the same time of day.  Forms: Quantitative CMV Immune Competence Assay Patient Information Sheet (Supply T592) in Special Instructions. | 10 mL | Hemolysis	Mild OK; Gross reject Thawing	NA Lipemia	Mild OK; Gross reject Icterus	NA Other	NA | Total CD3 T cells: 884-5,830 x 10(3)/mL Total CD8 T cells: 168-1,847 x 10(3)/mL Total CMV CD8 T cells: 0-115 x 10(3)/mL   The adult reference values were determined for healthy adult controls ages 20 to 80 years (n=94), for [NAME], A2, B7, B8, and B35 alleles.   Reference values for CMV-specific T cells that are functional (interferon-gamma+, IFN-g+) and have cytotoxic activity (CD107a and CD107b expression, [NAME] a/b+): Total CMV CD8 T-cells IFN-g: 0.028-52.200 x 10(3)/mL Total CMV CD8 T-cells CD107a/b: 0.252-50.760 x 10(3)/mL   The 95% confidence interval reference values were determined from 102 healthy adult donors: Interferon-gamma (IFN-gamma) expression (as % CD8 T cells): 10.3-56.0% CD107a/b expression (as % CD8 T cells): 8.5-49.1%   The reference values were developed for each of the following 4 major histocompatibility complex class I alleles: A1, A2, [NAME], and [NAME] (n=45). We were unable to develop ranges for the B35 allele due to a lack of matching donors. The data is expressed as the absolute number of CMV-specific CD8 T cells that are IFN-gamma+ or CD107a/b+. | Monday through Friday Specimens are required to be received in the laboratory on weekdays and by 4 p.m. on Friday. No weekend processing | 3 days | 4 days |  | Profile |  |  |  |  | Rochester
CMVC8 | [NAME] | WBNAH | WB Sodium Heparin |  |  |  | Ambient | 48 hours
CMVC8 | Result | 28143 | Total CD3 T cells | Total CD3 T cells | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | 8122-4 | Cells.CD3:NCnc:Pt:[NAME]:Qn:
CMVC8 | Result | 28144 | Total CD8 T cells | Total CD8 T cells | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | 8137-2 | Cells.CD8:NCnc:Pt:[NAME]:Qn:
CMVC8 | Result | 28145 | [NAME] T cells A1 | [NAME] T cells A1 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28146 | [NAME] cells A2 | [NAME] cells A2 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28147 | [NAME] T cells B7 | [NAME] T cells B7 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28148 | [NAME] T cells B8 | [NAME] T cells B8 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28149 | [NAME] T cells B35 | [NAME] T cells B35 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28150 | Total CMV CD8 T cells | Total CMV CD8 T cells | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28151 | [NAME] T cells IFN-g A1 | [NAME] T cells IFN-g A1 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28152 | [NAME] T cells IFN-g A2 | [NAME] T cells IFN-g A2 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28153 | [NAME] T cells IFN-g B7 | [NAME] T cells IFN-g B7 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28154 | [NAME] T cells IFN-g B8 | [NAME] T cells IFN-g B8 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28155 | [NAME] T cells IFN-g B35 | [NAME] T cells IFN-g B35 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28156 | Total CMV CD8 T cells IFN-g | Total CMV CD8 T cells IFN-g | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28157 | [NAME] T cells CD107 A1 | [NAME] T cells CD107 A1 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28158 | [NAME] T cells [NAME] | [NAME] T cells [NAME] | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28159 | [NAME] T cells [NAME] | [NAME] T cells [NAME] | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28160 | [NAME] T cells CD107 B8 | [NAME] T cells CD107 B8 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28161 | [NAME] T cells CD107 B35 | [NAME] T cells CD107 B35 | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28162 | Total CMV CD8 T cells CD107a/b | Total CMV CD8 T cells CD107a/b | Alphanumeric |  |  |  |  | cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 30693 | IFN-gamma expression | IFN-gamma expression | Alphanumeric |  |  |  |  | % CD8 T-Cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 30694 | CD107a/b expression | CD107a/b expression | Alphanumeric |  |  |  |  | % CD8 T-Cells |  |  |  |  |  |  |  |  |  | In Process
CMVC8 | Result | 28163 | Interpretation | Interpretation | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 69052-9
CMVC8 | Billing Component | CMVC8 |  | Each [NAME] |  |  |  |  |  |  |  |  |  |  |  |  |  | 2 | 88185
CMVC8 | Billing Component | CMVC8 |  | Flw Cytomtry First Marker |  |  |  |  |  |  |  |  |  |  |  |  |  | 1 | 88184