Spreadsheet: 0512a52f-f7f1-4c3e-b941-8e247426895f
Sheet: Suppl. Table S1 Vein

Annotation Cluster 1 | Enrichment Score: 5.614845886765641
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | glycoprotein | 47 | 47.9591836734693 | 4.99283356636326e-08 | PAM, IGFBP6, TSPAN5, TLR2, IFI30, PLVAP, ABCA1, C1QC, CD74, S1PR1, UNC5A, CRISPLD2, P4HA1, P4HA3, COL6A3, [NAME], LRRC70, SLC39A8, SEPP1, THBS1, FCGR3B, [NAME], SVEP1, LIPA, LY96, GALNTL2, GOLIM4, HBA2, C4BPA, HBA1, PTGFR, ADIPOQ, PROC, PCOLCE2, CD163, GGT5, TNFAIP6, CTSK, [NAME], CCL14, SFRP4, PECAM1, COL1A2, CYBRD1, SGCE, IGFBP2, RCN1, IL3RA | 98 | 4318 | 19235 | 2.1363939276498 | 1.27815725702307e-05 | 1.27815725702307e-05 | 6.51036326071441e-05
SP_PIR_KEYWORDS | signal | 38 | 38.7755102040816 | 4.57513176540494e-07 | PAM, IGFBP6, TLR2, IFI30, C1QC, CRISPLD2, P4HA1, UNC5A, P4HA3, COL6A3, LRRC70, SEPP1, MGC29506, COL8A1, THBS1, FCGR3B, [NAME], LIPA, SVEP1, EGFL7, RNASE4, LY96, [NAME], ADIPOQ, CD163, PCOLCE2, PROC, TNFAIP6, CTSK, MAGT1, [NAME], CCL14, SFRP4, PECAM1, COL1A2, IGFBP2, IL3RA, RCN1 | 98 | 3250 | 19235 | 2.2949136577708 | 0.000117116541316075 | 5.85599852939155e-05 | 0.000596568987720758
UP_SEQ_FEATURE | signal peptide | 38 | 38.7755102040816 | 5.37773230350379e-07 | PAM, IGFBP6, TLR2, IFI30, C1QC, CRISPLD2, P4HA1, UNC5A, P4HA3, COL6A3, LRRC70, SEPP1, MGC29506, COL8A1, THBS1, FCGR3B, [NAME], LIPA, SVEP1, EGFL7, RNASE4, LY96, [NAME], ADIPOQ, CD163, PCOLCE2, PROC, TNFAIP6, CTSK, MAGT1, [NAME], CCL14, SFRP4, PECAM1, COL1A2, IGFBP2, IL3RA, RCN1 | 98 | 3250 | 19113 | 2.28035792778649 | 0.000258635541431129 | 0.000258635541431129 | 0.000770193865240465
UP_SEQ_FEATURE | disulfide bond | 34 | 34.6938775510204 | 1.62562528403017e-06 | PAM, IGFBP6, TLR2, IFI30, ABCA1, UQCRFS1, C1QC, CD74, CRISPLD2, UNC5A, COL6A3, [NAME], THBS1, FCGR3B, [NAME], SVEP1, EGFL7, LGALS3, RNASE4, LY96, GALNTL2, [NAME], PTGFR, ADIPOQ, CD163, PCOLCE2, PROC, TNFAIP6, CTSK, CCL14, PRDX6, PECAM1, SFRP4, IGFBP2 | 98 | 2819 | 19113 | 2.35226705084304 | 0.000781620772407398 | 0.000390886782442034 | 0.00232818868199924
SP_PIR_KEYWORDS | disulfide bond | 34 | 34.6938775510204 | 3.2035261291257e-06 | PAM, IGFBP6, TLR2, IFI30, ABCA1, UQCRFS1, C1QC, CD74, CRISPLD2, UNC5A, COL6A3, [NAME], THBS1, FCGR3B, [NAME], SVEP1, EGFL7, LGALS3, RNASE4, LY96, GALNTL2, [NAME], PTGFR, ADIPOQ, CD163, PCOLCE2, PROC, TNFAIP6, CTSK, CCL14, PRDX6, PECAM1, SFRP4, IGFBP2 | 98 | 2924 | 19235 | 2.28227337446606 | 0.000819767809297933 | 0.000273330639264157 | 0.00417713160401067
GOTERM_CC_FAT | GO:0005576~extracellular region | 30 | 30.6122448979591 | 7.57532932821304e-06 | PAM, IGFBP6, IFI30, C1QC, [NAME], CRISPLD2, COL6A3, MGC29506, SEPP1, COL8A1, THBS1, FCGR3B, [NAME], SVEP1, EGFL7, LGALS3, LY96, RNASE4, C4BPA, ADIPOQ, PCOLCE2, CD163, PROC, CTSK, CCL14, PPIA, PECAM1, SFRP4, COL1A2, IGFBP2 | 82 | 2010 | 12782 | 2.32653804149981 | 0.00146097583228255 | 0.00146097583228255 | 0.00943906916065495
UP_SEQ_FEATURE | glycosylation site:N-linked (GlcNAc...) | 41 | 41.8367346938775 | 9.97354466333273e-06 | PAM, [NAME], TLR2, IFI30, PLVAP, ABCA1, CD74, S1PR1, UNC5A, CRISPLD2, P4HA1, P4HA3, COL6A3, [NAME], LRRC70, SLC39A8, SEPP1, THBS1, FCGR3B, [NAME], LIPA, SVEP1, LY96, GALNTL2, GOLIM4, C4BPA, PTGFR, CD163, PCOLCE2, PROC, GGT5, TNFAIP6, CTSK, SDC1, SFRP4, PECAM1, COL1A2, CYBRD1, SGCE, IL3RA, RCN1 | 98 | 4129 | 19113 | 1.93660816227677 | 0.00478581024661239 | 0.001597821756806 | 0.0142831210292793
SP_PIR_KEYWORDS | Secreted | 21 | 21.4285714285714 | 0.000249449857077416 | PAM, SVEP1, EGFL7, RNASE4, LY96, IGFBP6, C4BPA, C1QC, ADIPOQ, CD163, PCOLCE2, CCL14, CRISPLD2, COL6A3, SFRP4, COL1A2, MGC29506, SEPP1, COL8A1, IGFBP2, FCGR3B | 98 | 1689 | 19235 | 2.44037046434915 | 0.061870359057691 | 0.00707122810834015 | 0.324780157255488
Annotation Cluster 2 | Enrichment Score: 4.214019848005807
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0005576~extracellular region | 30 | 30.6122448979591 | 7.57532932821304e-06 | PAM, IGFBP6, IFI30, C1QC, [NAME], CRISPLD2, COL6A3, MGC29506, SEPP1, COL8A1, THBS1, FCGR3B, [NAME], SVEP1, EGFL7, LGALS3, LY96, RNASE4, C4BPA, ADIPOQ, PCOLCE2, CD163, PROC, CTSK, CCL14, PPIA, PECAM1, SFRP4, COL1A2, IGFBP2 | 82 | 2010 | 12782 | 2.32653804149981 | 0.00146097583228255 | 0.00146097583228255 | 0.00943906916065495
GOTERM_CC_FAT | GO:0044421~extracellular region part | 18 | 18.3673469387755 | 8.72592895489384e-05 | LGALS3, EGFL7, LY96, IGFBP6, ADIPOQ, RTN3, CTSK, CCL14, CRISPLD2, PECAM1, COL6A3, SFRP4, COL1A2, SEPP1, THBS1, COL8A1, IGFBP2, THBS4 | 82 | 960 | 12782 | 2.92271341463414 | 0.0167007477977673 | 0.00838553247633955 | 0.108677847065052
GOTERM_CC_FAT | GO:0005615~extracellular space | 14 | 14.2857142857142 | 0.000344927058859717 | EGFL7, LY96, IGFBP6, ADIPOQ, RTN3, CTSK, CCL14, PECAM1, SFRP4, COL6A3, COL1A2, SEPP1, THBS1, IGFBP2 | 82 | 685 | 12782 | 3.18582873419975 | 0.0644141852583239 | 0.0219496575284329 | 0.428958756288833
Annotation Cluster 3 | Enrichment Score: 3.9840558787703735
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | oxidoreductase | 13 | 13.2653061224489 | 2.56039608536459e-05 | PAM, SCD, IFI30, UQCRFS1, PHYH, ALDH1A1, RDH10, CYP27A1, PRDX6, P4HA1, P4HA3, CYBRD1, FASN | 98 | 562 | 19235 | 4.54018084101968 | 0.00653326271903209 | 0.0013100806724754 | 0.0333809337837553
SP_PIR_KEYWORDS | iron | 9 | 9.18367346938775 | 9.730900937504e-05 | CYP27A1, P4HA1, SCD, P4HA3, CYCS, CYBRD1, HBA2, HBA1, UQCRFS1, PHYH | 98 | 285 | 19235 | 6.19817400644468 | 0.0246045676021693 | 0.00355257725718716 | 0.126811001705773
GOTERM_BP_FAT | GO:0055114~oxidation reduction | 14 | 14.2857142857142 | 9.98542121408012e-05 | PAM, SCD, CYCS, IFI30, UQCRFS1, PHYH, ALDH1A1, RDH10, CYP27A1, PRDX6, P4HA1, P4HA3, CYBRD1, FASN | 82 | 639 | 13528 | 3.6144891026375 | 0.1083114434275 | 0.1083114434275 | 0.160420296821806
GOTERM_MF_FAT | GO:0005506~iron ion binding | 9 | 9.18367346938775 | 0.000465532375712398 | CYP27A1, P4HA1, SCD, P4HA3, CYCS, CYBRD1, HBA2, HBA1, UQCRFS1, PHYH | 78 | 308 | 12983 | 4.86376123876123 | 0.123871034991633 | 0.0217992163459163 | 0.61513429544967
Annotation Cluster 4 | Enrichment Score: 3.0467150930797455
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0005539~glycosaminoglycan binding | 7 | 7.14285714285714 | 0.00017860152998774 | TNFAIP6, CCL14, CRISPLD2, TLR2, THBS1, PCOLCE2, THBS4 | 78 | 140 | 12983 | 8.32243589743589 | 0.0494622145834444 | 0.0494622145834444 | 0.236411293728766
GOTERM_MF_FAT | GO:0030246~carbohydrate binding | 10 | 10.204081632653 | 0.000236885457269237 | TNFAIP6, CCL14, LGALS3, CRISPLD2, [NAME], GALNTL2, TLR2, THBS1, PCOLCE2, THBS4 | 78 | 354 | 12983 | 4.70194118499203 | 0.0650698322801272 | 0.0221781794652333 | 0.313448671783689
GOTERM_MF_FAT | GO:0030247~polysaccharide binding | 7 | 7.14285714285714 | 0.000299334555065942 | TNFAIP6, CCL14, CRISPLD2, TLR2, THBS1, PCOLCE2, THBS4 | 78 | 154 | 12983 | 7.56585081585081 | 0.0815095204037008 | 0.0168609832308151 | 0.395930369000996
GOTERM_MF_FAT | GO:0001871~pattern binding | 7 | 7.14285714285714 | 0.000299334555065942 | TNFAIP6, CCL14, CRISPLD2, TLR2, THBS1, PCOLCE2, THBS4 | 78 | 154 | 12983 | 7.56585081585081 | 0.0815095204037008 | 0.0168609832308151 | 0.395930369000996
GOTERM_MF_FAT | GO:0008201~heparin binding | 5 | 5.10204081632653 | 0.0032449326953005 | CCL14, CRISPLD2, THBS1, PCOLCE2, THBS4 | 78 | 103 | 12983 | 8.08003485187951 | 0.602698296879455 | 0.123541232981917 | 4.21551418061928
SP_PIR_KEYWORDS | heparin-binding | 3 | 3.06122448979591 | 0.0426350193688427 | CCL14, THBS1, PCOLCE2 | 98 | 65 | 19235 | 9.05886970172684 | 0.999985683080641 | 0.33841291077209 | 43.3418917980674
Annotation Cluster 5 | Enrichment Score: 2.6722881013853113
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | [NAME] | 7 | 7.14285714285714 | 8.51543829054817e-06 | P4HA1, COL6A3, COL1A2, COL8A1, C1QC, ADIPOQ, PCOLCE2 | 98 | 95 | 19235 | 14.4624060150375 | 0.00217758709368265 | 0.000544841890733782 | 0.0111030681825941
SP_PIR_KEYWORDS | hydroxylation | 6 | 6.12244897959183 | 2.94113672666512e-05 | COL6A3, COL1A2, COL8A1, C1QC, ADIPOQ, PROC | 98 | 71 | 19235 | 16.5866628341477 | 0.00750114566718973 | 0.00125411639559969 | 0.038343926865636
SP_PIR_KEYWORDS | hydroxyproline | 4 | 4.08163265306122 | 0.000852973558331577 | COL6A3, COL1A2, C1QC, ADIPOQ | 98 | 37 | 19235 | 21.2189740761169 | 0.196239879656247 | 0.0180398327594285 | 1.10653499991795
INTERPRO | IPR008160:Collagen triple helix repeat | 5 | 5.10204081632653 | 0.00119968362164703 | COL6A3, COL1A2, COL8A1, C1QC, ADIPOQ | 93 | 84 | 16659 | 10.6624423963133 | 0.272475069502142 | 0.272475069502142 | 1.56140957040666
SP_PIR_KEYWORDS | hydroxylysine | 3 | 3.06122448979591 | 0.0106417285086885 | COL6A3, COL1A2, C1QC | 98 | 31 | 19235 | 18.9944042132982 | 0.93535740381377 | 0.15733021038738 | 13.021182824891
SP_PIR_KEYWORDS | triple helix | 3 | 3.06122448979591 | 0.0106417285086885 | COL6A3, COL1A2, C1QC | 98 | 31 | 19235 | 18.9944042132982 | 0.93535740381377 | 0.15733021038738 | 13.021182824891
UP_SEQ_FEATURE | domain:C1q | 3 | 3.06122448979591 | 0.0107714999573894 | COL8A1, C1QC, ADIPOQ | 98 | 31 | 19113 | 18.8739302172481 | 0.994533941859458 | 0.478554071429951 | 14.3675470639723
INTERPRO | IPR001073:Complement C1q protein | 3 | 3.06122448979591 | 0.0134370499746408 | COL8A1, C1QC, ADIPOQ | 93 | 32 | 16659 | 16.7933467741935 | 0.972262172394576 | 0.591898575074592 | 16.251657495836
SMART | SM00110:C1Q | 3 | 3.06122448979591 | 0.0175955016522402 | COL8A1, C1QC, ADIPOQ | 59 | 32 | 9079 | 14.426377118644 | 0.678943169803734 | 0.433381230282418 | 16.5017550569911
INTERPRO | IPR008983:Tumour necrosis factor-like | 3 | 3.06122448979591 | 0.0256087480720915 | COL8A1, C1QC, ADIPOQ | 93 | 45 | 16659 | 11.9419354838709 | 0.998966418571547 | 0.576558823971379 | 28.8303717372061
Annotation Cluster 6 | Enrichment Score: 2.5653208220612567
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0031410~cytoplasmic vesicle | 12 | 12.2448979591836 | 0.00231780274949813 | PAM, PRDX6, [NAME], PECAM1, GOLIM4, GALNTL2, FASN, AP3S1, ABCA1, IGFBP2, THBS1, THBS4 | 82 | 642 | 12782 | 2.91360838842033 | 0.361002764774134 | 0.105923366633945 | 2.85011926040542
GOTERM_CC_FAT | GO:0016023~cytoplasmic membrane-bounded vesicle | 11 | 11.2244897959183 | 0.00241063106457153 | PAM, PRDX6, [NAME], PECAM1, GOLIM4, GALNTL2, FASN, AP3S1, ABCA1, THBS1, THBS4 | 82 | 550 | 12782 | 3.11756097560975 | 0.372375658314148 | 0.0889547340028091 | 2.96269517287295
GOTERM_CC_FAT | GO:0031988~membrane-bounded vesicle | 11 | 11.2244897959183 | 0.00304202107903701 | PAM, PRDX6, [NAME], PECAM1, GOLIM4, GALNTL2, FASN, AP3S1, ABCA1, THBS1, THBS4 | 82 | 568 | 12782 | 3.01876502919958 | 0.444565664058534 | 0.0933518342603346 | 3.72522461656016
GOTERM_CC_FAT | GO:0031982~vesicle | 12 | 12.2448979591836 | 0.00322364544951829 | PAM, PRDX6, [NAME], PECAM1, GOLIM4, GALNTL2, FASN, AP3S1, ABCA1, IGFBP2, THBS1, THBS4 | 82 | 670 | 12782 | 2.79184564979978 | 0.463757368440743 | 0.0851764542716286 | 3.9435493565778
Annotation Cluster 7 | Enrichment Score: 2.47254085273113
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
UP_SEQ_FEATURE | domain:[NAME] type-1 | 3 | 3.06122448979591 | 0.00191723179433975 | IGFBP6, IGFBP2, CD74 | 98 | 13 | 19113 | 45.0070643642072 | 0.602703986095956 | 0.168575454773571 | 2.71105990209654
INTERPRO | IPR000716:[NAME] type-1 | 3 | 3.06122448979591 | 0.00388736973434212 | IGFBP6, IGFBP2, CD74 | 93 | 17 | 16659 | 31.6110056925996 | 0.643763512034209 | 0.40314449992834 | 4.97808955927468
SMART | SM00211:TY | 3 | 3.06122448979591 | 0.00512916854474249 | IGFBP6, IGFBP2, CD74 | 59 | 17 | 9079 | 27.1555333998006 | 0.280437251027786 | 0.280437251027786 | 5.09003459015637
Annotation Cluster 8 | Enrichment Score: 2.3936940928846457
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | [NAME]~response to endogenous stimulus | 11 | 11.2244897959183 | 0.000145891556135722 | SDC1, [NAME], PPARG, AP3S1, FABP4, GNG11, UQCRFS1, IGFBP2, THBS1, ADIPOQ, MGST1 | 82 | 405 | 13528 | 4.48081903041252 | 0.154219766878924 | 0.0803368915080504 | 0.234300053932312
GOTERM_BP_FAT | GO:0042493~response to drug | 8 | 8.16326530612245 | 0.000306786050089802 | PPARG, TLR2, FABP4, UQCRFS1, IGFBP2, ADIPOQ, MGST1, APC | 82 | 216 | 13528 | 6.11020776874435 | 0.296891752818108 | 0.110783736213462 | 0.49209764162349
GOTERM_BP_FAT | GO:0009725~response to hormone stimulus | 10 | 10.204081632653 | 0.000336381318393608 | SDC1, [NAME], PPARG, AP3S1, FABP4, GNG11, UQCRFS1, IGFBP2, THBS1, ADIPOQ | 82 | 367 | 13528 | 4.49524822223699 | 0.320386291224062 | 0.0920424743462646 | 0.539449388882584
GOTERM_BP_FAT | GO:0010033~response to organic substance | 13 | 13.2653061224489 | 0.00114713644884283 | LY96, PPARG, TLR2, AP3S1, GNG11, UQCRFS1, ADIPOQ, SDC1, BTG2, FABP4, THBS1, IGFBP2, MGST1 | 82 | 721 | 13528 | 2.97459490544974 | 0.732241161697768 | 0.23166828009881 | 1.82845006998628
GOTERM_BP_FAT | GO:0048545~response to steroid hormone stimulus | 6 | 6.12244897959183 | 0.00586307711871963 | SDC1, PPARG, FABP4, IGFBP2, THBS1, ADIPOQ | 82 | 192 | 13528 | 5.15548780487804 | 0.998829848012673 | 0.430246690912544 | 9.02098667391907
GOTERM_BP_FAT | GO:0051384~response to glucocorticoid stimulus | 4 | 4.08163265306122 | 0.0114000766049303 | SDC1, FABP4, IGFBP2, ADIPOQ | 82 | 78 | 13528 | 8.46028767979987 | 0.999998078602603 | 0.518691892109783 | 16.8345363038044
GOTERM_BP_FAT | GO:0031960~response to corticosteroid stimulus | 4 | 4.08163265306122 | 0.0143667720349812 | SDC1, FABP4, IGFBP2, ADIPOQ | 82 | 85 | 13528 | 7.76355810616929 | 0.999999939017407 | 0.514361287341604 | 20.7575283743809
GOTERM_BP_FAT | GO:0032870~cellular response to hormone stimulus | 4 | 4.08163265306122 | 0.0455307307856047 | PPARG, AP3S1, GNG11, IGFBP2 | 82 | 133 | 13528 | 4.96167247386759 | 1 | 0.746326653238867 | 52.7260627140624
GOTERM_BP_FAT | GO:0009628~response to abiotic stimulus | 4 | 4.08163265306122 | 0.379090808070106 | BTG2, PPARG, IGFBP2, THBS1 | 82 | 368 | 13528 | 1.79321314952279 | 1 | 0.98560835502071 | 99.9529673875203
Annotation Cluster 9 | Enrichment Score: 2.352532563666711
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | vitamin c | 4 | 4.08163265306122 | 0.000113606100618973 | PAM, P4HA1, P4HA3, PHYH | 98 | 19 | 19235 | 41.3211600429645 | 0.0286659216544756 | 0.00362900093870421 | 0.148034498026361
GOTERM_MF_FAT | GO:0031406~carboxylic acid binding | 7 | 7.14285714285714 | 0.000208207283080037 | PAM, P4HA1, P4HA3, PPARG, FASN, FABP4, PHYH | 78 | 144 | 12983 | 8.09125712250712 | 0.0574223963770074 | 0.0291356409760462 | 0.275549876989189
GOTERM_MF_FAT | GO:0031418~L-ascorbic acid binding | 4 | 4.08163265306122 | 0.000247035929217435 | PAM, P4HA1, P4HA3, PHYH | 78 | 21 | 12983 | 31.7045177045177 | 0.0677617567175754 | 0.0173887575505538 | 0.326859537485291
GOTERM_MF_FAT | GO:0019842~vitamin binding | 5 | 5.10204081632653 | 0.00739487516550715 | PAM, P4HA1, P4HA3, FASN, PHYH | 78 | 130 | 12983 | 6.40187376725838 | 0.878513021589432 | 0.20880946862564 | 9.36735720567504
UP_SEQ_FEATURE | metal ion-binding site:Iron | 3 | 3.06122448979591 | 0.0228264023162709 | P4HA1, P4HA3, PHYH | 98 | 46 | 19113 | 12.719387755102 | 0.99998498935499 | 0.708898547316455 | 28.1584913191319
SP_PIR_KEYWORDS | dioxygenase | 3 | 3.06122448979591 | 0.0438260892503059 | P4HA1, P4HA3, PHYH | 98 | 66 | 19235 | 8.92161410018553 | 0.999989590166514 | 0.336178118884759 | 44.2541761712128
GOTERM_MF_FAT | GO:0016702~oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | 3 | 3.06122448979591 | 0.0583746078763614 | P4HA1, P4HA3, PHYH | 78 | 66 | 12983 | 7.56585081585081 | 0.999999961858496 | 0.788367862244808 | 54.9336935153611
GOTERM_MF_FAT | GO:0016701~oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | 3 | 3.06122448979591 | 0.0599455278060697 | P4HA1, P4HA3, PHYH | 78 | 67 | 12983 | 7.45292766934558 | 0.999999976261261 | 0.768462430498325 | 55.9198658830742
Annotation Cluster 10 | Enrichment Score: 2.2421090706263436
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | [NAME] | 7 | 7.14285714285714 | 8.51543829054817e-06 | P4HA1, COL6A3, COL1A2, COL8A1, C1QC, ADIPOQ, PCOLCE2 | 98 | 95 | 19235 | 14.4624060150375 | 0.00217758709368265 | 0.000544841890733782 | 0.0111030681825941
SP_PIR_KEYWORDS | hydroxylation | 6 | 6.12244897959183 | 2.94113672666512e-05 | COL6A3, COL1A2, COL8A1, C1QC, ADIPOQ, PROC | 98 | 71 | 19235 | 16.5866628341477 | 0.00750114566718973 | 0.00125411639559969 | 0.038343926865636
INTERPRO | IPR008160:Collagen triple helix repeat | 5 | 5.10204081632653 | 0.00119968362164703 | COL6A3, COL1A2, COL8A1, C1QC, ADIPOQ | 93 | 84 | 16659 | 10.6624423963133 | 0.272475069502142 | 0.272475069502142 | 1.56140957040666
GOTERM_CC_FAT | GO:0005581~collagen | 3 | 3.06122448979591 | 0.0206151119219709 | COL6A3, COL1A2, COL8A1 | 82 | 35 | 12782 | 13.360975609756 | 0.98205241896486 | 0.360264195107579 | 22.8613633256876
GOTERM_CC_FAT | GO:0031012~extracellular matrix | 7 | 7.14285714285714 | 0.0220850982894001 | LGALS3, CRISPLD2, COL6A3, COL1A2, COL8A1, THBS1, THBS4 | 82 | 345 | 12782 | 3.16274301873453 | 0.98656909229279 | 0.350153870700297 | 24.2917271762158
GOTERM_CC_FAT | GO:0005578~proteinaceous extracellular matrix | 5 | 5.10204081632653 | 0.145076684365464 | LGALS3, COL6A3, COL1A2, COL8A1, THBS4 | 82 | 320 | 12782 | 2.43559451219512 | 0.999999999999927 | 0.731601494327696 | 85.8173676354536
GOTERM_CC_FAT | GO:0044420~extracellular matrix part | 3 | 3.06122448979591 | 0.169600216601289 | COL6A3, COL1A2, COL8A1 | 82 | 117 | 12782 | 3.99687304565353 | 0.999999999999999 | 0.761824330779193 | 90.1314591254424
SP_PIR_KEYWORDS | extracellular matrix | 3 | 3.06122448979591 | 0.3435812278044 | COL6A3, COL1A2, COL8A1 | 98 | 241 | 19235 | 2.44326361249894 | 1 | 0.879129511891606 | 99.5868133893754
Annotation Cluster 11 | Enrichment Score: 2.0663340921245577
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0045596~negative regulation of cell differentiation | 7 | 7.14285714285714 | 0.00185353402892949 | LMO2, PPARG, ABCA1, C1QC, ADIPOQ, CD74, APC | 82 | 216 | 13528 | 5.34643179765131 | 0.881142684317388 | 0.262332167815126 | 2.93874723821506
GOTERM_BP_FAT | GO:0045637~regulation of myeloid cell differentiation | 4 | 4.08163265306122 | 0.00848724097171209 | LMO2, C1QC, ADIPOQ, APC | 82 | 70 | 13528 | 9.42717770034843 | 0.999943706707824 | 0.528901143743493 | 12.8061498483287
GOTERM_BP_FAT | GO:0045638~negative regulation of myeloid cell differentiation | 3 | 3.06122448979591 | 0.0138187511231895 | LMO2, C1QC, ADIPOQ | 82 | 30 | 13528 | 16.4975609756097 | 0.999999884564796 | 0.532657630932589 | 20.0461822574802
GOTERM_BP_FAT | GO:0002761~regulation of myeloid [NAME] differentiation | 3 | 3.06122448979591 | 0.024970528812843 | C1QC, ADIPOQ, APC | 82 | 41 | 13528 | 12.0713860797144 | 0.999999999999753 | 0.620033221553109 | 33.4064403324971
Annotation Cluster 12 | Enrichment Score: 2.027229268509668
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0045596~negative regulation of cell differentiation | 7 | 7.14285714285714 | 0.00185353402892949 | LMO2, PPARG, ABCA1, C1QC, ADIPOQ, CD74, APC | 82 | 216 | 13528 | 5.34643179765131 | 0.881142684317388 | 0.262332167815126 | 2.93874723821506
GOTERM_BP_FAT | GO:0010745~negative regulation of foam cell differentiation | 3 | 3.06122448979591 | 0.00224788335920489 | PPARG, ABCA1, ADIPOQ | 82 | 12 | 13528 | 41.2439024390243 | 0.924488843129052 | 0.275978620665543 | 3.55344199097088
GOTERM_BP_FAT | GO:0010743~regulation of foam cell differentiation | 3 | 3.06122448979591 | 0.00971581454129949 | PPARG, ABCA1, ADIPOQ | 82 | 25 | 13528 | 19.7970731707317 | 0.999986438728878 | 0.503672001597499 | 14.5270526681268
GOTERM_BP_FAT | GO:0048878~chemical homeostasis | 6 | 6.12244897959183 | 0.192233633034301 | CCL14, S1PR1, PPARG, FABP4, ABCA1, ADIPOQ | 82 | 512 | 13528 | 1.93330792682926 | 1 | 0.926260062563903 | 96.768661685281
Annotation Cluster 13 | Enrichment Score: 2.0051925200721796
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | trimer | 4 | 4.08163265306122 | 0.000297118965221412 | COL6A3, COL1A2, THBS1, THBS4 | 98 | 26 | 19235 | 30.1962323390894 | 0.0732521502272163 | 0.00757851286736588 | 0.386733706276243
UP_SEQ_FEATURE | short sequence motif:Cell attachment site | 5 | 5.10204081632653 | 0.0010491649277662 | SVEP1, COL6A3, IGFBP2, THBS1, THBS4 | 98 | 88 | 19113 | 11.0812847866419 | 0.396442065313927 | 0.118586412878991 | 1.49215390440474
KEGG_PATHWAY | hsa04512:ECM-receptor interaction | 5 | 5.10204081632653 | 0.00776151187627467 | SDC1, COL6A3, COL1A2, THBS1, THBS4 | 49 | 84 | 5085 | 6.1771137026239 | 0.392664855268018 | 0.220682898473297 | 7.61051662875622
GOTERM_CC_FAT | GO:0031012~extracellular matrix | 7 | 7.14285714285714 | 0.0220850982894001 | LGALS3, CRISPLD2, COL6A3, COL1A2, COL8A1, THBS1, THBS4 | 82 | 345 | 12782 | 3.16274301873453 | 0.98656909229279 | 0.350153870700297 | 24.2917271762158
KEGG_PATHWAY | hsa04510:Focal adhesion | 5 | 5.10204081632653 | 0.120068049931316 | PAK3, COL6A3, COL1A2, THBS1, THBS4 | 49 | 201 | 5085 | 2.58148035333536 | 0.999721553621492 | 0.870822940762152 | 72.7317958452624
GOTERM_CC_FAT | GO:0005578~proteinaceous extracellular matrix | 5 | 5.10204081632653 | 0.145076684365464 | LGALS3, COL6A3, COL1A2, COL8A1, THBS4 | 82 | 320 | 12782 | 2.43559451219512 | 0.999999999999927 | 0.731601494327696 | 85.8173676354536
Annotation Cluster 14 | Enrichment Score: 1.9812116635018062
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
UP_SEQ_FEATURE | short sequence motif:Cell attachment site | 5 | 5.10204081632653 | 0.0010491649277662 | SVEP1, COL6A3, IGFBP2, THBS1, THBS4 | 98 | 88 | 19113 | 11.0812847866419 | 0.396442065313927 | 0.118586412878991 | 1.49215390440474
SP_PIR_KEYWORDS | cell adhesion | 7 | 7.14285714285714 | 0.0199771058513932 | TNFAIP6, [NAME], COL6A3, PECAM1, COL8A1, THBS1, THBS4 | 98 | 422 | 19235 | 3.25575490859851 | 0.994292148699932 | 0.227633137655002 | 23.1355698785724
GOTERM_BP_FAT | GO:0007155~cell adhesion | 10 | 10.204081632653 | 0.023720532354978 | TNFAIP6, SVEP1, S1PR1, COL6A3, PECAM1, SGCE, COL8A1, THBS1, THBS4, APC | 82 | 700 | 13528 | 2.3567944250871 | 0.999999999998925 | 0.639663260591171 | 32.0204971972483
GOTERM_BP_FAT | GO:0022610~biological adhesion | 10 | 10.204081632653 | 0.0239140195180252 | TNFAIP6, SVEP1, S1PR1, COL6A3, PECAM1, SGCE, COL8A1, THBS1, THBS4, APC | 82 | 701 | 13528 | 2.35343237883163 | 0.999999999999144 | 0.629309823638215 | 32.23678252022
Annotation Cluster 15 | Enrichment Score: 1.6894997223733212
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0048545~response to steroid hormone stimulus | 6 | 6.12244897959183 | 0.00586307711871963 | SDC1, PPARG, FABP4, IGFBP2, THBS1, ADIPOQ | 82 | 192 | 13528 | 5.15548780487804 | 0.998829848012673 | 0.430246690912544 | 9.02098667391907
GOTERM_BP_FAT | [NAME]~response to inorganic substance | 5 | 5.10204081632653 | 0.0345046678114979 | SDC1, [NAME], CYBRD1, IGFBP2, THBS1 | 82 | 205 | 13528 | 4.02379535990481 | 1 | 0.705224722416796 | 43.1382453056606
GOTERM_BP_FAT | GO:0010038~response to metal ion | 4 | 4.08163265306122 | 0.0422179727853292 | SDC1, CYBRD1, IGFBP2, THBS1 | 82 | 129 | 13528 | 5.1155227831348 | 1 | 0.737722597015633 | 50.0179350347893
Annotation Cluster 16 | Enrichment Score: 1.6179854255849129
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
UP_SEQ_FEATURE | short sequence motif:Cell attachment site | 5 | 5.10204081632653 | 0.0010491649277662 | SVEP1, COL6A3, IGFBP2, THBS1, THBS4 | 98 | 88 | 19113 | 11.0812847866419 | 0.396442065313927 | 0.118586412878991 | 1.49215390440474
SP_PIR_KEYWORDS | calcium binding | 5 | 5.10204081632653 | 0.00183469199756557 | THBS1, [NAME], [NAME], PROC, THBS4 | 98 | 103 | 19235 | 9.52793738854765 | 0.375068065030501 | 0.0330219347524425 | 2.36608778849084
UP_SEQ_FEATURE | domain:EGF-like 2; calcium-binding | 4 | 4.08163265306122 | 0.00304036962351713 | SVEP1, EGFL7, THBS1, THBS4 | 98 | 57 | 19113 | 13.6863587540279 | 0.768840065444375 | 0.216596644970426 | 4.26731205747208
UP_SEQ_FEATURE | domain:EGF-like 1 | 5 | 5.10204081632653 | 0.0032673614617395 | SVEP1, EGFL7, THBS1, PROC, THBS4 | 98 | 120 | 19113 | 8.12627551020408 | 0.792821380881722 | 0.201389546603688 | 4.57901206935411
INTERPRO | IPR013320:[NAME] lectin/glucanase, subgroup | 4 | 4.08163265306122 | 0.00888051616947311 | SVEP1, LGALS3, THBS1, THBS4 | 93 | 77 | 16659 | 9.3054042731462 | 0.905942453456981 | 0.545223639199093 | 11.0364536444951
INTERPRO | IPR018097:EGF-like calcium-binding, conserved site | 4 | 4.08163265306122 | 0.0160953848357321 | SVEP1, EGFL7, PROC, THBS4 | 93 | 96 | 16659 | 7.46370967741935 | 0.986431107819145 | 0.576835839599288 | 19.1623119075475
INTERPRO | IPR000742:EGF-like, type 3 | 5 | 5.10204081632653 | 0.0225220028442163 | SVEP1, EGFL7, THBS1, PROC, THBS4 | 93 | 194 | 16659 | 4.61672763551712 | 0.997610250236698 | 0.634355758727428 | 25.8172785950773
INTERPRO | IPR006210:EGF-like | 5 | 5.10204081632653 | 0.0252433393545646 | SVEP1, EGFL7, THBS1, PROC, THBS4 | 93 | 201 | 16659 | 4.45594607607125 | 0.998858447109955 | 0.620123619696784 | 28.4796772649038
SP_PIR_KEYWORDS | egf-like domain | 5 | 5.10204081632653 | 0.0291176159993358 | SVEP1, EGFL7, THBS1, PROC, THBS4 | 98 | 230 | 19235 | 4.26685891748003 | 0.99948161190111 | 0.261099090883173 | 31.9763098289071
SMART | SM00181:EGF | 5 | 5.10204081632653 | 0.0391166135237387 | SVEP1, EGFL7, THBS1, PROC, THBS4 | 59 | 201 | 9079 | 3.82789442617421 | 0.922209992719592 | 0.573117906872474 | 33.3268549111536
SP_PIR_KEYWORDS | calcium | 9 | 9.18367346938775 | 0.0498226185188408 | SVEP1, EGFL7, GALNTL2, THBS1, [NAME], [NAME], [NAME], PROC, THBS4 | 98 | 803 | 19235 | 2.19985005210054 | 0.999997920302658 | 0.344293208622737 | 48.6446122215261
INTERPRO | IPR013091:EGF calcium-binding | 3 | 3.06122448979591 | 0.0601164345749112 | SVEP1, EGFL7, THBS4 | 93 | 72 | 16659 | 7.46370967741935 | 0.999999926780836 | 0.838868470719163 | 55.6390137107708
INTERPRO | IPR013032:EGF-like region, conserved site | 5 | 5.10204081632653 | 0.079066372961435 | SVEP1, EGFL7, THBS1, PROC, THBS4 | 93 | 293 | 16659 | 3.05680942419905 | 0.999999999668481 | 0.837803188599724 | 66.0348254917391
GOTERM_MF_FAT | GO:0005509~calcium ion binding | 10 | 10.204081632653 | 0.0930478517974251 | SVEP1, EGFL7, GALNTL2, SGCE, THBS1, [NAME], [NAME], [NAME], PROC, THBS4 | 78 | 919 | 12983 | 1.81119388409921 | 0.9999999999991 | 0.881591820297756 | 72.588154278276
INTERPRO | IPR001881:EGF-like calcium-binding | 3 | 3.06122448979591 | 0.0986472644549265 | EGFL7, PROC, THBS4 | 93 | 96 | 16659 | 5.59778225806451 | 0.999999999998885 | 0.879621906349271 | 74.3745723495108
INTERPRO | IPR000152:EGF-type aspartate/asparagine hydroxylation conserved site | 3 | 3.06122448979591 | 0.100375755178445 | SVEP1, EGFL7, PROC | 93 | 97 | 16659 | 5.54007316262055 | 0.999999999999329 | 0.864965973486234 | 75.0113817354929
SMART | SM00179:EGF_CA | 3 | 3.06122448979591 | 0.125179413818567 | EGFL7, PROC, THBS4 | 59 | 96 | 9079 | 4.80879237288135 | 0.999808214560389 | 0.759857364791603 | 74.2988092700556
INTERPRO | IPR006209:EGF | 3 | 3.06122448979591 | 0.155581040344421 | SVEP1, THBS1, PROC | 93 | 127 | 16659 | 4.23139446278892 | 1 | 0.949589124364473 | 89.1062865927961
Annotation Cluster 17 | Enrichment Score: 1.5459535930846744
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0006631~fatty acid metabolic process | 7 | 7.14285714285714 | 0.00118953663891384 | GGT5, LIPA, SCD, FASN, FABP4, ADIPOQ, CD74 | 82 | 198 | 13528 | 5.83247105198324 | 0.744976840063085 | 0.203663533449741 | 1.89542816348807
GOTERM_BP_FAT | GO:0006633~fatty acid biosynthetic process | 4 | 4.08163265306122 | 0.0117997618339712 | GGT5, SCD, FASN, CD74 | 82 | 79 | 13528 | 8.35319543068848 | 0.999998792165452 | 0.511879881794875 | 17.3734722837136
GOTERM_BP_FAT | GO:0046394~carboxylic acid biosynthetic process | 4 | 4.08163265306122 | 0.0659520692491526 | GGT5, SCD, FASN, CD74 | 82 | 155 | 13528 | 4.25743509047993 | 1 | 0.765539143616248 | 66.6105872415247
GOTERM_BP_FAT | GO:0016053~organic acid biosynthetic process | 4 | 4.08163265306122 | 0.0659520692491526 | GGT5, SCD, FASN, CD74 | 82 | 155 | 13528 | 4.25743509047993 | 1 | 0.765539143616248 | 66.6105872415247
GOTERM_BP_FAT | GO:0008610~lipid biosynthetic process | 4 | 4.08163265306122 | 0.305157548617622 | GGT5, SCD, FASN, CD74 | 82 | 323 | 13528 | 2.04304160688665 | 1 | 0.974427820585138 | 99.7129747841494
Annotation Cluster 18 | Enrichment Score: 1.4947564401111704
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | lysosome | 5 | 5.10204081632653 | 0.00686594925930077 | CTSK, LIPA, PRDX6, IFI30, CD74 | 98 | 149 | 19235 | 6.58642651691549 | 0.828598214269011 | 0.110933275221945 | 8.59196080046029
GOTERM_CC_FAT | GO:0000323~lytic vacuole | 5 | 5.10204081632653 | 0.0448919109271576 | CTSK, LIPA, PRDX6, IFI30, CD74 | 82 | 211 | 12782 | 3.69379262513004 | 0.999858701684211 | 0.522274875691553 | 43.5793414198738
GOTERM_CC_FAT | GO:0005764~lysosome | 5 | 5.10204081632653 | 0.0448919109271576 | CTSK, LIPA, PRDX6, IFI30, CD74 | 82 | 211 | 12782 | 3.69379262513004 | 0.999858701684211 | 0.522274875691553 | 43.5793414198738
GOTERM_CC_FAT | GO:0005773~vacuole | 5 | 5.10204081632653 | 0.0758468353500046 | CTSK, LIPA, PRDX6, IFI30, CD74 | 82 | 252 | 12782 | 3.09281842818428 | 0.999999755328534 | 0.570761099758306 | 62.5767321811181
Annotation Cluster 19 | Enrichment Score: 1.4669170728397962
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0042493~response to drug | 8 | 8.16326530612245 | 0.000306786050089802 | PPARG, TLR2, FABP4, UQCRFS1, IGFBP2, ADIPOQ, MGST1, APC | 82 | 216 | 13528 | 6.11020776874435 | 0.296891752818108 | 0.110783736213462 | 0.49209764162349
GOTERM_BP_FAT | GO:0048545~response to steroid hormone stimulus | 6 | 6.12244897959183 | 0.00586307711871963 | SDC1, PPARG, FABP4, IGFBP2, THBS1, ADIPOQ | 82 | 192 | 13528 | 5.15548780487804 | 0.998829848012673 | 0.430246690912544 | 9.02098667391907
GOTERM_BP_FAT | GO:0007584~response to nutrient | 3 | 3.06122448979591 | 0.204522911588159 | PPARG, IGFBP2, ADIPOQ | 82 | 140 | 13528 | 3.53519163763066 | 1 | 0.935185433721658 | 97.4745623506143
GOTERM_BP_FAT | GO:0031667~response to nutrient levels | 3 | 3.06122448979591 | 0.330624602383037 | PPARG, IGFBP2, ADIPOQ | 82 | 197 | 13528 | 2.5123189302959 | 1 | 0.97850979434802 | 99.8425303290454
GOTERM_BP_FAT | GO:0009991~response to extracellular stimulus | 3 | 3.06122448979591 | 0.38051894809625 | PPARG, IGFBP2, ADIPOQ | 82 | 220 | 13528 | 2.24966740576496 | 1 | 0.985430404277889 | 99.9546768008759
Annotation Cluster 20 | Enrichment Score: 1.4656833513045493
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0031012~extracellular matrix | 7 | 7.14285714285714 | 0.0220850982894001 | LGALS3, CRISPLD2, COL6A3, COL1A2, COL8A1, THBS1, THBS4 | 82 | 345 | 12782 | 3.16274301873453 | 0.98656909229279 | 0.350153870700297 | 24.2917271762158
GOTERM_BP_FAT | GO:0030198~extracellular matrix organization | 4 | 4.08163265306122 | 0.0244394108741532 | LGALS3, P4HA1, CRISPLD2, COL1A2 | 82 | 104 | 13528 | 6.3452157598499 | 0.999999999999538 | 0.624494407101825 | 32.8208288061486
GOTERM_BP_FAT | GO:0043062~extracellular structure organization | 4 | 4.08163265306122 | 0.0742608433263345 | LGALS3, P4HA1, CRISPLD2, COL1A2 | 82 | 163 | 13528 | 4.04848122100852 | 1 | 0.788617355804206 | 71.0785947752744
Annotation Cluster 21 | Enrichment Score: 1.4462143654186181
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0006954~inflammatory response | 8 | 8.16326530612245 | 0.00329133254170316 | TNFAIP6, LIPA, LY96, TLR2, C4BPA, THBS1, C1QC, CD163 | 82 | 325 | 13528 | 4.06093808630394 | 0.97728390336179 | 0.315090215106386 | 5.16236222015735
GOTERM_BP_FAT | GO:0009611~response to wounding | 10 | 10.204081632653 | 0.00431972525605236 | TNFAIP6, [NAME], LIPA, LY96, TLR2, C4BPA, THBS1, C1QC, PROC, CD163 | 82 | 530 | 13528 | 3.11274735388863 | 0.99305536871305 | 0.363517759478564 | 6.72341074652876
GOTERM_BP_FAT | GO:0006952~defense response | 10 | 10.204081632653 | 0.0110490992364635 | TNFAIP6, LIPA, LY96, PPARG, TLR2, C4BPA, THBS1, C1QC, CD74, CD163 | 82 | 615 | 13528 | 2.68253023993654 | 0.999997112044738 | 0.527771297825967 | 16.3585613214791
GOTERM_BP_FAT | GO:0048584~positive regulation of response to stimulus | 6 | 6.12244897959183 | 0.0135653078286088 | S1PR1, TLR2, FABP4, C4BPA, THBS1, C1QC | 82 | 236 | 13528 | 4.19429516329061 | 0.999999844957185 | 0.54341400912296 | 19.7151847628651
SP_PIR_KEYWORDS | immune response | 5 | 5.10204081632653 | 0.026774407523669 | LY96, TLR2, [NAME], C1QC, CD74 | 98 | 224 | 19235 | 4.3811497813411 | 0.99903913729027 | 0.260715905496973 | 29.804196080076
GOTERM_BP_FAT | GO:0045087~innate immune response | 4 | 4.08163265306122 | 0.0498482976674358 | PPARG, TLR2, [NAME], C1QC | 82 | 138 | 13528 | 4.78190173206079 | 1 | 0.769507028057012 | 56.0493711618586
GOTERM_BP_FAT | GO:0006955~immune response | 9 | 9.18367346938775 | 0.0539113118635734 | CCL14, LY96, PPARG, TLR2, C4BPA, THBS1, C1QC, FCGR3B, CD74 | 82 | 690 | 13528 | 2.15185577942735 | 1 | 0.764473334480182 | 58.9755135060902
GOTERM_BP_FAT | GO:0002684~positive regulation of immune system process | 5 | 5.10204081632653 | 0.0544193121678662 | TLR2, [NAME], THBS1, C1QC, CD74 | 82 | 238 | 13528 | 3.46587415453986 | 1 | 0.760092334085535 | 59.3282399163768
SP_PIR_KEYWORDS | innate immunity | 3 | 3.06122448979591 | 0.0590381351508692 | TLR2, [NAME], C1QC | 98 | 78 | 19235 | 7.54905808477236 | 0.999999828431391 | 0.359235823181035 | 54.7733402054028
GOTERM_BP_FAT | GO:0002253~activation of immune response | 3 | 3.06122448979591 | 0.108899649552807 | TLR2, [NAME], C1QC | 82 | 94 | 13528 | 5.26517903476907 | 1 | 0.84906273466533 | 84.3345554216071
GOTERM_BP_FAT | GO:0050778~positive regulation of immune response | 3 | 3.06122448979591 | 0.215482678605432 | TLR2, [NAME], C1QC | 82 | 145 | 13528 | 3.41328847771236 | 1 | 0.941743551790618 | 97.9794612065794
GOTERM_BP_FAT | GO:0007243~protein kinase cascade | 4 | 4.08163265306122 | 0.38235658177214 | LY96, TLR2, THBS1, CD74 | 82 | 370 | 13528 | 1.78352010547132 | 1 | 0.985339107180607 | 99.9567907075966
Annotation Cluster 22 | Enrichment Score: 1.3031924547116587
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | [NAME]lipid binding | 8 | 8.16326530612245 | 0.0171429154407624 | ALDH1A1, SNX9, S1PR1, PPARG, SNX2, FABP4, ABCA1, TENC1 | 78 | 450 | 12983 | 2.95908831908831 | 0.992633422215419 | 0.388035009067126 | 20.4779155899103
GOTERM_BP_FAT | GO:0055088~lipid homeostasis | 3 | 3.06122448979591 | 0.0373687507213357 | PPARG, FABP4, ABCA1 | 82 | 51 | 13528 | 9.70444763271162 | 1 | 0.723604942921476 | 45.7903454163519
GOTERM_BP_FAT | GO:0048878~chemical homeostasis | 6 | 6.12244897959183 | 0.192233633034301 | CCL14, S1PR1, PPARG, FABP4, ABCA1, ADIPOQ | 82 | 512 | 13528 | 1.93330792682926 | 1 | 0.926260062563903 | 96.768661685281
Annotation Cluster 23 | Enrichment Score: 1.296299292743388
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0060249~anatomical structure homeostasis | 4 | 4.08163265306122 | 0.025673122309895 | CTSK, LIPA, FH, APC | 82 | 106 | 13528 | 6.22549470777726 | 0.999999999999892 | 0.618311644760246 | 34.173767846701
GOTERM_BP_FAT | GO:0001894~tissue homeostasis | 3 | 3.06122448979591 | 0.0546845322679949 | CTSK, LIPA, FH | 82 | 63 | 13528 | 7.85598141695702 | 1 | 0.754257098169367 | 59.5112616023824
GOTERM_BP_FAT | GO:0048871~multicellular organismal homeostasis | 3 | 3.06122448979591 | 0.0919938786740918 | CTSK, LIPA, FH | 82 | 85 | 13528 | 5.82266857962697 | 1 | 0.822900463164064 | 78.8080814434003
Annotation Cluster 24 | Enrichment Score: 1.2371895987077721
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | heme | 4 | 4.08163265306122 | 0.0233383474790967 | CYP27A1, CYCS, CYBRD1, HBA2, [NAME] | 98 | 121 | 19235 | 6.48844661831674 | 0.997631361342596 | 0.250146998933071 | 26.5030215272051
SP_PIR_KEYWORDS | metalloprotein | 4 | 4.08163265306122 | 0.0248646848843955 | CYP27A1, P4HA1, CYCS, HBA2, [NAME] | 98 | 124 | 19235 | 6.3314680710994 | 0.998412877129472 | 0.253972176535199 | 27.9867442481611
SP_PIR_KEYWORDS | chromoprotein | 3 | 3.06122448979591 | 0.0391373285704688 | CYP27A1, CYCS, HBA2, [NAME] | 98 | 62 | 19235 | 9.49720210664911 | 0.999963583485172 | 0.325035849110654 | 40.5825925149648
GOTERM_MF_FAT | GO:0020037~heme binding | 3 | 3.06122448979591 | 0.16118228971482 | CYP27A1, CYCS, HBA2, [NAME] | 78 | 121 | 12983 | 4.1268277177368 | 1 | 0.946936027300401 | 90.2613851159693
GOTERM_MF_FAT | GO:0046906~tetrapyrrole binding | 3 | 3.06122448979591 | 0.178028874328686 | CYP27A1, CYCS, HBA2, [NAME] | 78 | 129 | 12983 | 3.87090041741204 | 1 | 0.946626011065718 | 92.5571426758121
Annotation Cluster 25 | Enrichment Score: 1.2046666887899666
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | LIM domain | 3 | 3.06122448979591 | 0.0499633781002729 | CRIP1, LMO2, CRIP2 | 98 | 71 | 19235 | 8.29333141707387 | 0.999997997701756 | 0.336374945596747 | 48.7437251493572
INTERPRO | [NAME]:Zinc finger, LIM-type | 3 | 3.06122448979591 | 0.0615937733512195 | CRIP1, LMO2, CRIP2 | 93 | 73 | 16659 | 7.36146707909854 | 0.999999951740433 | 0.814493837473292 | 56.5444972513917
SMART | SM00132:LIM | 3 | 3.06122448979591 | 0.07903352072956 | CRIP1, LMO2, CRIP2 | 59 | 73 | 9079 | 6.32389133967959 | 0.9948524011814 | 0.7321441270049 | 56.6736721339754
Annotation Cluster 26 | Enrichment Score: 1.1909723456562176
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | immune response | 5 | 5.10204081632653 | 0.026774407523669 | LY96, TLR2, [NAME], C1QC, CD74 | 98 | 224 | 19235 | 4.3811497813411 | 0.99903913729027 | 0.260715905496973 | 29.804196080076
GOTERM_BP_FAT | [NAME] mediated immune response | 3 | 3.06122448979591 | 0.0414637395827111 | C4BPA, C1QC, CD74 | 82 | 54 | 13528 | 9.16531165311653 | 1 | 0.740870426326403 | 49.3813548759484
GOTERM_BP_FAT | GO:0019724~B cell mediated immunity | 3 | 3.06122448979591 | 0.0442833435674022 | C4BPA, C1QC, CD74 | 82 | 56 | 13528 | 8.83797909407665 | 1 | 0.745473256508916 | 51.7229149361838
GOTERM_BP_FAT | GO:0002684~positive regulation of immune system process | 5 | 5.10204081632653 | 0.0544193121678662 | TLR2, [NAME], THBS1, C1QC, CD74 | 82 | 238 | 13528 | 3.46587415453986 | 1 | 0.760092334085535 | 59.3282399163768
GOTERM_BP_FAT | GO:0002449~[NAME] mediated immunity | 3 | 3.06122448979591 | 0.0658507082174434 | C4BPA, C1QC, CD74 | 82 | 70 | 13528 | 7.07038327526132 | 1 | 0.771331863001177 | 66.5522849274129
GOTERM_BP_FAT | GO:0002460~adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | 3 | 3.06122448979591 | 0.0777029394967866 | C4BPA, C1QC, CD74 | 82 | 77 | 13528 | 6.42762115932847 | 1 | 0.787253817912894 | 72.7598820904101
GOTERM_BP_FAT | GO:0002250~adaptive immune response | 3 | 3.06122448979591 | 0.0777029394967866 | C4BPA, C1QC, CD74 | 82 | 77 | 13528 | 6.42762115932847 | 1 | 0.787253817912894 | 72.7598820904101
GOTERM_BP_FAT | [NAME] mediated immunity | 3 | 3.06122448979591 | 0.0938312814906514 | C4BPA, C1QC, CD74 | 82 | 86 | 13528 | 5.75496313102665 | 1 | 0.824512465163915 | 79.4871175712997
GOTERM_BP_FAT | GO:0002252~immune effector process | 3 | 3.06122448979591 | 0.191462667027708 | C4BPA, C1QC, CD74 | 82 | 134 | 13528 | 3.69348380050964 | 1 | 0.927449264766489 | 96.7187181414388
Annotation Cluster 27 | Enrichment Score: 1.1619703489359747
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0032101~regulation of response to external stimulus | 6 | 6.12244897959183 | 0.00263100975945022 | S1PR1, PPARG, FABP4, THBS1, ADIPOQ, PROC | 82 | 159 | 13528 | 6.22549470777726 | 0.951412041040266 | 0.285407029745062 | 4.14714496380748
KEGG_PATHWAY | hsa03320:PPAR signaling pathway | 5 | 5.10204081632653 | 0.00385534235879633 | CYP27A1, SCD, PPARG, FABP4, ADIPOQ | 49 | 69 | 5085 | 7.51996450754214 | 0.21903018126582 | 0.21903018126582 | 3.84822357245119
GOTERM_BP_FAT | GO:0048545~response to steroid hormone stimulus | 6 | 6.12244897959183 | 0.00586307711871963 | SDC1, PPARG, FABP4, IGFBP2, THBS1, ADIPOQ | 82 | 192 | 13528 | 5.15548780487804 | 0.998829848012673 | 0.430246690912544 | 9.02098667391907
GOTERM_BP_FAT | GO:0050873~brown fat cell differentiation | 3 | 3.06122448979591 | 0.00897315137159478 | PPARG, FABP4, ADIPOQ | 82 | 24 | 13528 | 20.6219512195121 | 0.999967932680715 | 0.522465805355601 | 13.4906282991911
GOTERM_BP_FAT | GO:0001818~negative regulation of cytokine production | 3 | 3.06122448979591 | 0.0216555322861389 | PPARG, THBS1, ADIPOQ | 82 | 38 | 13528 | 13.0243902439024 | 0.999999999987849 | 0.619656398784274 | 29.6715005952478
GOTERM_BP_FAT | GO:0045444~fat cell differentiation | 3 | 3.06122448979591 | 0.0400805613099641 | PPARG, FABP4, ADIPOQ | 82 | 53 | 13528 | 9.33824206166589 | 1 | 0.73860276282532 | 48.1941361951609
GOTERM_BP_FAT | GO:0051241~negative regulation of multicellular organismal process | 4 | 4.08163265306122 | 0.0753309846703919 | PPARG, THBS1, ADIPOQ, PROC | 82 | 164 | 13528 | 4.02379535990481 | 1 | 0.787791185714872 | 71.6114521912999
GOTERM_BP_FAT | GO:0050727~regulation of inflammatory response | 3 | 3.06122448979591 | 0.0759706129655179 | PPARG, FABP4, ADIPOQ | 82 | 76 | 13528 | 6.51219512195121 | 1 | 0.785055286674051 | 71.9255327307744
GOTERM_BP_FAT | GO:0001817~regulation of cytokine production | 4 | 4.08163265306122 | 0.0945461507476399 | PPARG, TLR2, THBS1, ADIPOQ | 82 | 181 | 13528 | 3.64586982886403 | 1 | 0.822280381329156 | 79.7457500615072
GOTERM_BP_FAT | GO:0048878~chemical homeostasis | 6 | 6.12244897959183 | 0.192233633034301 | CCL14, S1PR1, PPARG, FABP4, ABCA1, ADIPOQ | 82 | 512 | 13528 | 1.93330792682926 | 1 | 0.926260062563903 | 96.768661685281
GOTERM_BP_FAT | GO:0010605~negative regulation of macromolecule metabolic process | 7 | 7.14285714285714 | 0.275949387732255 | PPARG, FABP4, ZEB2, THBS1, ADIPOQ, [NAME], RPS27A | 82 | 734 | 13528 | 1.57333687778294 | 1 | 0.965604826109649 | 99.443547474854
GOTERM_MF_FAT | GO:0046983~protein dimerization activity | 5 | 5.10204081632653 | 0.401822031840939 | PPARG, PLVAP, ADIPOQ, [NAME], MGST1 | 78 | 542 | 12983 | 1.5355047781247 | 1 | 0.993476552819327 | 99.8896644896859
GOTERM_BP_FAT | GO:0010558~negative regulation of macromolecule biosynthetic process | 5 | 5.10204081632653 | 0.415578950885277 | PPARG, FABP4, ZEB2, ADIPOQ, S100A1 | 82 | 547 | 13528 | 1.50800374548535 | 1 | 0.988158943056983 | 99.9822367031281
GOTERM_BP_FAT | [NAME] regulation of cellular biosynthetic process | 5 | 5.10204081632653 | 0.434536966744656 | PPARG, FABP4, ZEB2, ADIPOQ, S100A1 | 82 | 561 | 13528 | 1.47037085344115 | 1 | 0.988698112543399 | 99.9895463763926
GOTERM_BP_FAT | GO:0009890~negative regulation of biosynthetic process | 5 | 5.10204081632653 | 0.450663228176465 | PPARG, FABP4, ZEB2, ADIPOQ, S100A1 | 82 | 573 | 13528 | 1.4395777465628 | 1 | 0.98979298791185 | 99.9934348649752
GOTERM_BP_FAT | GO:0010604~positive regulation of macromolecule metabolic process | 6 | 6.12244897959183 | 0.589152431368671 | S1PR1, PPARG, THBS1, ADIPOQ, RPS27A, APC | 82 | 857 | 13528 | 1.15502177192133 | 1 | 0.99770833255752 | 99.9999384917844
Annotation Cluster 28 | Enrichment Score: 1.1429313862325572
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0045596~negative regulation of cell differentiation | 7 | 7.14285714285714 | 0.00185353402892949 | LMO2, PPARG, ABCA1, C1QC, ADIPOQ, CD74, APC | 82 | 216 | 13528 | 5.34643179765131 | 0.881142684317388 | 0.262332167815126 | 2.93874723821506
GOTERM_BP_FAT | GO:0030097~hemopoiesis | 5 | 5.10204081632653 | 0.0530662265719756 | LMO2, CRIP2, PPARG, CD74, APC | 82 | 236 | 13528 | 3.49524596940884 | 1 | 0.774713115757095 | 58.3823716204631
GOTERM_BP_FAT | GO:0048534~hemopoietic or lymphoid organ development | 5 | 5.10204081632653 | 0.0705292437643106 | LMO2, CRIP2, PPARG, CD74, APC | 82 | 260 | 13528 | 3.17260787992495 | 1 | 0.782733354358029 | 69.1462172387452
GOTERM_BP_FAT | GO:0051338~regulation of transferase activity | 6 | 6.12244897959183 | 0.0721607995271135 | PPARG, FABP4, ZEB2, THBS1, CD74, APC | 82 | 372 | 13528 | 2.66089693154996 | 1 | 0.784627275509686 | 70.0055406255341
GOTERM_BP_FAT | GO:0002520~immune system development | 5 | 5.10204081632653 | 0.0836258832490176 | LMO2, CRIP2, PPARG, CD74, APC | 82 | 276 | 13528 | 2.98868858253799 | 1 | 0.801511509617786 | 75.4402561407061
GOTERM_BP_FAT | GO:0002521~[NAME] differentiation | 3 | 3.06122448979591 | 0.184977079208322 | PPARG, CD74, APC | 82 | 131 | 13528 | 3.7780673989946 | 1 | 0.922097055620064 | 96.2689718195489
GOTERM_BP_FAT | GO:0051094~positive regulation of developmental process | 4 | 4.08163265306122 | 0.232235670651399 | PPARG, THBS1, CD74, APC | 82 | 278 | 13528 | 2.37374978066327 | 1 | 0.95040224434187 | 98.5719398158843
GOTERM_BP_FAT | GO:0045597~positive regulation of cell differentiation | 3 | 3.06122448979591 | 0.399642818947451 | PPARG, CD74, APC | 82 | 229 | 13528 | 2.16125252955586 | 1 | 0.986525357374837 | 99.9726239112114
Annotation Cluster 29 | Enrichment Score: 1.1154179225660852
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | cell adhesion | 7 | 7.14285714285714 | 0.0199771058513932 | TNFAIP6, [NAME], COL6A3, PECAM1, COL8A1, THBS1, THBS4 | 98 | 422 | 19235 | 3.25575490859851 | 0.994292148699932 | 0.227633137655002 | 23.1355698785724
GOTERM_CC_FAT | GO:0031091~platelet alpha granule | 3 | 3.06122448979591 | 0.0490107126250627 | PECAM1, THBS1, THBS4 | 82 | 56 | 12782 | 8.35060975609756 | 0.999938638554924 | 0.499809546685401 | 46.5373522393986
GOTERM_CC_FAT | GO:0030141~secretory granule | 4 | 4.08163265306122 | 0.106054385555684 | PAM, PECAM1, THBS1, THBS4 | 82 | 180 | 12782 | 3.46395663956639 | 0.999999999599094 | 0.626005218130806 | 75.2658764756522
GOTERM_CC_FAT | GO:0044433~cytoplasmic vesicle part | 3 | 3.06122448979591 | 0.332641238921301 | PECAM1, THBS1, THBS4 | 82 | 187 | 12782 | 2.50071736011477 | 1 | 0.912769687621188 | 99.3522994256527
Annotation Cluster 30 | Enrichment Score: 1.040914349269954
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0030155~regulation of cell adhesion | 5 | 5.10204081632653 | 0.00917880769927864 | S1PR1, COL8A1, THBS1, ADIPOQ, APC | 82 | 137 | 13528 | 6.02100765533202 | 0.999974730919081 | 0.506251302385549 | 13.7788059802895
GOTERM_BP_FAT | GO:0051129~negative regulation of cellular component organization | 4 | 4.08163265306122 | 0.0534416631212614 | S1PR1, THBS1, ADIPOQ, APC | 82 | 142 | 13528 | 4.64720027481964 | 1 | 0.769223996296935 | 58.6468660246567
GOTERM_BP_FAT | GO:0044087~regulation of cellular component biogenesis | 4 | 4.08163265306122 | 0.0534416631212614 | S1PR1, THBS1, RPS27A, APC | 82 | 142 | 13528 | 4.64720027481964 | 1 | 0.769223996296935 | 58.6468660246567
GOTERM_BP_FAT | GO:0030334~regulation of cell migration | 4 | 4.08163265306122 | 0.0807842707960484 | S1PR1, EGFL7, THBS1, APC | 82 | 169 | 13528 | 3.90474815990763 | 1 | 0.795106420111181 | 74.1867766258895
GOTERM_BP_FAT | GO:0030335~positive regulation of cell migration | 3 | 3.06122448979591 | 0.0994068771417375 | S1PR1, THBS1, APC | 82 | 89 | 13528 | 5.56097560975609 | 1 | 0.833705245041021 | 81.4248730086419
GOTERM_BP_FAT | GO:0040012~regulation of locomotion | 4 | 4.08163265306122 | 0.107949763964952 | S1PR1, EGFL7, THBS1, APC | 82 | 192 | 13528 | 3.43699186991869 | 1 | 0.850516520340575 | 84.0639099926888
GOTERM_BP_FAT | GO:0051270~regulation of cell motion | 4 | 4.08163265306122 | 0.109203687931385 | S1PR1, EGFL7, THBS1, APC | 82 | 193 | 13528 | 3.41918362188803 | 1 | 0.845841878374283 | 84.4202686013685
GOTERM_BP_FAT | GO:0040017~positive regulation of locomotion | 3 | 3.06122448979591 | 0.116660974879781 | S1PR1, THBS1, APC | 82 | 98 | 13528 | 5.0502737680438 | 1 | 0.850241894058446 | 86.3899113729229
GOTERM_BP_FAT | GO:0051272~positive regulation of cell motion | 3 | 3.06122448979591 | 0.116660974879781 | S1PR1, THBS1, APC | 82 | 98 | 13528 | 5.0502737680438 | 1 | 0.850241894058446 | 86.3899113729229
GOTERM_BP_FAT | GO:0051247~positive regulation of protein metabolic process | 4 | 4.08163265306122 | 0.178285013234795 | THBS1, ADIPOQ, RPS27A, APC | 82 | 243 | 13528 | 2.71564789721971 | 1 | 0.916020122289937 | 95.7447400196939
GOTERM_BP_FAT | GO:0010604~positive regulation of macromolecule metabolic process | 6 | 6.12244897959183 | 0.589152431368671 | S1PR1, PPARG, THBS1, ADIPOQ, RPS27A, APC | 82 | 857 | 13528 | 1.15502177192133 | 1 | 0.99770833255752 | 99.9999384917844
Annotation Cluster 31 | Enrichment Score: 1.0245966616942097
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | endoplasmic reticulum | 9 | 9.18367346938775 | 0.0275772048259245 | MAGT1, RDH10, P4HA1, SCD, P4HA3, CD74, MGST1, RCN1, RTN3 | 98 | 713 | 19235 | 2.47753098434324 | 0.999222118397314 | 0.257913161362586 | 30.5554841241607
GOTERM_CC_FAT | GO:0005783~endoplasmic reticulum | 11 | 11.2244897959183 | 0.0809672684857504 | MAGT1, RDH10, P4HA1, SCD, P4HA3, ADIPOQ, [NAME], CD74, MGST1, RCN1, RTN3 | 82 | 960 | 12782 | 1.78610264227642 | 0.999999916270408 | 0.575849536455562 | 65.0800142718764
GOTERM_CC_FAT | GO:0044432~endoplasmic reticulum part | 4 | 4.08163265306122 | 0.377876846150264 | MAGT1, P4HA1, P4HA3, RCN1 | 82 | 347 | 12782 | 1.79686511562521 | 1 | 0.932400225332136 | 99.7298958884516
Annotation Cluster 32 | Enrichment Score: 0.9495369570921918
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | plasma | 4 | 4.08163265306122 | 0.0116285092388707 | SEPP1, C4BPA, C1QC, PROC | 98 | 93 | 19235 | 8.44195742813254 | 0.949930446610413 | 0.153252163974308 | 14.1456144709104
KEGG_PATHWAY | hsa04610:Complement and coagulation cascades | 3 | 3.06122448979591 | 0.137665884629052 | C4BPA, C1QC, PROC | 49 | 69 | 5085 | 4.51197870452528 | 0.999923574842478 | 0.84980783815678 | 77.7911495179063
GOTERM_BP_FAT | GO:0006508~proteolysis | 5 | 5.10204081632653 | 0.885194601430327 | CTSK, C4BPA, C1QC, RPS27A, PROC | 82 | 1054 | 13528 | 0.782616744573517 | 1 | 0.99999726282386 | 99.9999999999999
Annotation Cluster 33 | Enrichment Score: 0.9342859632977605
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0001568~blood vessel development | 5 | 5.10204081632653 | 0.0593023619575289 | S1PR1, LMO2, EGFL7, COL1A2, THBS1 | 82 | 245 | 13528 | 3.36684917869586 | 1 | 0.768253181170244 | 62.5767110004063
GOTERM_BP_FAT | GO:0001944~vasculature development | 5 | 5.10204081632653 | 0.0636690402346987 | S1PR1, LMO2, EGFL7, COL1A2, THBS1 | 82 | 251 | 13528 | 3.28636672820911 | 1 | 0.779190046359899 | 65.2740181714954
GOTERM_BP_FAT | GO:0030334~regulation of cell migration | 4 | 4.08163265306122 | 0.0807842707960484 | S1PR1, EGFL7, THBS1, APC | 82 | 169 | 13528 | 3.90474815990763 | 1 | 0.795106420111181 | 74.1867766258895
GOTERM_BP_FAT | GO:0040012~regulation of locomotion | 4 | 4.08163265306122 | 0.107949763964952 | S1PR1, EGFL7, THBS1, APC | 82 | 192 | 13528 | 3.43699186991869 | 1 | 0.850516520340575 | 84.0639099926888
GOTERM_BP_FAT | GO:0051270~regulation of cell motion | 4 | 4.08163265306122 | 0.109203687931385 | S1PR1, EGFL7, THBS1, APC | 82 | 193 | 13528 | 3.41918362188803 | 1 | 0.845841878374283 | 84.4202686013685
GOTERM_BP_FAT | GO:0001525~angiogenesis | 3 | 3.06122448979591 | 0.222085764626584 | S1PR1, EGFL7, THBS1 | 82 | 148 | 13528 | 3.34410019775873 | 1 | 0.945643858677043 | 98.2361995856753
GOTERM_BP_FAT | GO:0048514~blood vessel morphogenesis | 3 | 3.06122448979591 | 0.361153168315197 | S1PR1, EGFL7, THBS1 | 82 | 211 | 13528 | 2.34562478326205 | 1 | 0.983136484207198 | 99.9256541435334
Annotation Cluster 34 | Enrichment Score: 0.9323265971742524
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | electron transport | 3 | 3.06122448979591 | 0.0907254230691707 | CYCS, CYBRD1, UQCRFS1 | 98 | 100 | 19235 | 5.88826530612244 | 0.999999999973335 | 0.491517629169302 | 71.0660715250274
GOTERM_BP_FAT | GO:0006091~generation of precursor metabolites and energy | 5 | 5.10204081632653 | 0.118086748035664 | CYCS, CYBRD1, UQCRFS1, ADIPOQ, FH | 82 | 313 | 13528 | 2.63539312709421 | 1 | 0.850154611353024 | 86.7388323911616
GOTERM_BP_FAT | GO:0022900~electron transport chain | 3 | 3.06122448979591 | 0.148966990341687 | CYCS, CYBRD1, UQCRFS1 | 82 | 114 | 13528 | 4.34146341463414 | 1 | 0.892584748662911 | 92.5233000375752
Annotation Cluster 35 | Enrichment Score: 0.8255245910957578
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
UP_SEQ_FEATURE | repeat:LRR 13 | 3 | 3.06122448979591 | 0.0570259725783452 | COL6A3, TLR2, LRRC70 | 98 | 76 | 19113 | 7.6985767991407 | 0.999999999999457 | 0.940647767150613 | 56.8693315388419
UP_SEQ_FEATURE | repeat:LRR 12 | 3 | 3.06122448979591 | 0.0780803607221123 | COL6A3, TLR2, LRRC70 | 98 | 91 | 19113 | 6.42958062345817 | 1 | 0.971415927993381 | 68.7869978042385
UP_SEQ_FEATURE | repeat:LRR 11 | 3 | 3.06122448979591 | 0.0948215929638407 | COL6A3, TLR2, LRRC70 | 98 | 102 | 19113 | 5.73619447779111 | 1 | 0.974929392500448 | 75.9923987255811
UP_SEQ_FEATURE | repeat:LRR 5 | 4 | 4.08163265306122 | 0.113039152224536 | COL6A3, TLR2, LRRC70, [NAME] | 98 | 231 | 19113 | 3.37715345878611 | 1 | 0.983776455899832 | 82.057223176895
UP_SEQ_FEATURE | repeat:LRR 10 | 3 | 3.06122448979591 | 0.11910204817294 | COL6A3, TLR2, LRRC70 | 98 | 117 | 19113 | 5.00078492935635 | 1 | 0.98286249556887 | 83.736025092008
UP_SEQ_FEATURE | repeat:LRR 4 | 4 | 4.08163265306122 | 0.13653718020881 | COL6A3, TLR2, LRRC70, [NAME] | 98 | 252 | 19113 | 3.09572400388726 | 1 | 0.987884970311567 | 87.7852651961333
UP_SEQ_FEATURE | repeat:LRR 9 | 3 | 3.06122448979591 | 0.149982052425082 | COL6A3, TLR2, LRRC70 | 98 | 135 | 19113 | 4.33401360544217 | 1 | 0.989925343771025 | 90.2439937844858
UP_SEQ_FEATURE | repeat:LRR 8 | 3 | 3.06122448979591 | 0.17498180498574 | COL6A3, TLR2, LRRC70 | 98 | 149 | 19113 | 3.92679085056841 | 1 | 0.994142398878906 | 93.6379945019175
UP_SEQ_FEATURE | repeat:LRR 3 | 4 | 4.08163265306122 | 0.194252495461437 | COL6A3, TLR2, LRRC70, [NAME] | 98 | 299 | 19113 | 2.60910518053375 | 1 | 0.995779607423893 | 95.4649146261082
UP_SEQ_FEATURE | repeat:LRR 1 | 4 | 4.08163265306122 | 0.219114275691553 | COL6A3, TLR2, LRRC70, [NAME] | 98 | 318 | 19113 | 2.45321524836349 | 1 | 0.997389468274926 | 97.1050416220577
UP_SEQ_FEATURE | repeat:LRR 2 | 4 | 4.08163265306122 | 0.220441459747763 | COL6A3, TLR2, LRRC70, [NAME] | 98 | 319 | 19113 | 2.44552491843132 | 1 | 0.996667109880618 | 97.1747168371971
SP_PIR_KEYWORDS | leucine-rich repeat | 4 | 4.08163265306122 | 0.221715741036485 | COL6A3, TLR2, LRRC70, [NAME] | 98 | 322 | 19235 | 2.43820509570287 | 1 | 0.775150038183174 | 96.1936745782923
UP_SEQ_FEATURE | repeat:LRR 7 | 3 | 3.06122448979591 | 0.226610521290598 | COL6A3, TLR2, LRRC70 | 98 | 177 | 19113 | 3.30560359737115 | 1 | 0.99536480563036 | 97.4785844214038
UP_SEQ_FEATURE | repeat:LRR 6 | 3 | 3.06122448979591 | 0.288599499854681 | COL6A3, TLR2, LRRC70 | 98 | 210 | 19113 | 2.78615160349854 | 1 | 0.998572169820425 | 99.2379470861148
Annotation Cluster 36 | Enrichment Score: 0.7983464754491442
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0002684~positive regulation of immune system process | 5 | 5.10204081632653 | 0.0544193121678662 | TLR2, [NAME], THBS1, C1QC, CD74 | 82 | 238 | 13528 | 3.46587415453986 | 1 | 0.760092334085535 | 59.3282399163768
GOTERM_CC_FAT | GO:0009897~external side of plasma membrane | 4 | 4.08163265306122 | 0.0932393885292083 | S1PR1, TLR2, THBS1, CD74 | 82 | 170 | 12782 | 3.667718794835 | 0.999999993747109 | 0.593240990378807 | 70.4659049962215
GOTERM_BP_FAT | GO:0044093~positive regulation of molecular function | 7 | 7.14285714285714 | 0.138494936032535 | S1PR1, CYCS, TLR2, ZEB2, THBS1, CD74, RPS27A | 82 | 586 | 13528 | 1.97069841005577 | 1 | 0.882252979501434 | 90.898673231062
GOTERM_CC_FAT | [NAME]cell surface | 5 | 5.10204081632653 | 0.17897946122274 | SDC1, S1PR1, TLR2, THBS1, CD74 | 82 | 348 | 12782 | 2.23962713765068 | 1 | 0.768663950754237 | 91.4339387709279
GOTERM_BP_FAT | GO:0007242~intracellular signaling cascade | 10 | 10.204081632653 | 0.337180943470623 | S1PR1, LY96, COL1A2, TLR2, GNG11, ABCA1, THBS1, TENC1, [NAME], CD74 | 82 | 1256 | 13528 | 1.31350007767593 | 1 | 0.979137992378192 | 99.865578338094
GOTERM_BP_FAT | GO:0007243~protein kinase cascade | 4 | 4.08163265306122 | 0.38235658177214 | LY96, TLR2, THBS1, CD74 | 82 | 370 | 13528 | 1.78352010547132 | 1 | 0.985339107180607 | 99.9567907075966
Annotation Cluster 37 | Enrichment Score: 0.7730456733210999
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0022626~cytosolic ribosome | 4 | 4.08163265306122 | 0.0146775680882587 | RPLP1, FAU, HBA2, [NAME], RPS27A | 82 | 81 | 12782 | 7.69768142125865 | 0.942373077798804 | 0.300032012861562 | 16.827214301999
GOTERM_CC_FAT | GO:0022627~cytosolic small ribosomal subunit | 3 | 3.06122448979591 | 0.0264815501318685 | FAU, HBA2, [NAME], RPS27A | 82 | 40 | 12782 | 11.6908536585365 | 0.994371042002818 | 0.375556060029982 | 28.4253806581608
GOTERM_CC_FAT | GO:0033279~ribosomal subunit | 4 | 4.08163265306122 | 0.0476091237615966 | RPLP1, FAU, HBA2, [NAME], RPS27A | 82 | 128 | 12782 | 4.87118902439024 | 0.999918466014567 | 0.515283738257164 | 45.5471743772857
SP_PIR_KEYWORDS | ribosome | 3 | 3.06122448979591 | 0.0525004149322731 | RPLP1, FAU, RPS27A | 98 | 73 | 19235 | 8.06611685770198 | 0.999998990209492 | 0.341872499036855 | 50.5001226050318
GOTERM_CC_FAT | GO:0015935~small ribosomal subunit | 3 | 3.06122448979591 | 0.0604308258195026 | FAU, HBA2, [NAME], RPS27A | 82 | 63 | 12782 | 7.42276422764227 | 0.999994039939854 | 0.551581650158467 | 54.0092764850512
GOTERM_CC_FAT | GO:0044445~cytosolic part | 4 | 4.08163265306122 | 0.0719733106479583 | RPLP1, FAU, HBA2, [NAME], RPS27A | 82 | 152 | 12782 | 4.10205391527599 | 0.999999451508361 | 0.571731745843323 | 60.5745261058821
GOTERM_BP_FAT | GO:0006414~translational elongation | 3 | 3.06122448979591 | 0.122572142986655 | RPLP1, FAU, RPS27A | 82 | 101 | 13528 | 4.90026563631972 | 1 | 0.854055218902337 | 87.7825987731118
GOTERM_CC_FAT | GO:0005840~ribosome | 4 | 4.08163265306122 | 0.155710558755815 | RPLP1, FAU, HBA2, [NAME], RPS27A | 82 | 215 | 12782 | 2.90005672149744 | 0.999999999999993 | 0.743629527514963 | 87.8654885402836
KEGG_PATHWAY | hsa03010:Ribosome | 3 | 3.06122448979591 | 0.197949559045688 | RPLP1, FAU, RPS27A | 49 | 87 | 5085 | 3.57846586910626 | 0.999999260551992 | 0.904906403312466 | 89.3639128320733
SP_PIR_KEYWORDS | ribosomal protein | 3 | 3.06122448979591 | 0.244988028671126 | RPLP1, FAU, RPS27A | 98 | 188 | 19235 | 3.13205601389491 | 1 | 0.805054489535729 | 97.4379424939807
SP_PIR_KEYWORDS | protein biosynthesis | 3 | 3.06122448979591 | 0.244988028671126 | RPLP1, FAU, RPS27A | 98 | 188 | 19235 | 3.13205601389491 | 1 | 0.805054489535729 | 97.4379424939807
GOTERM_MF_FAT | GO:0003735~structural constituent of ribosome | 3 | 3.06122448979591 | 0.26287610179302 | RPLP1, FAU, RPS27A | 78 | 168 | 12983 | 2.97229853479853 | 1 | 0.972925372862402 | 98.2431253645249
GOTERM_MF_FAT | GO:0005198~structural molecule activity | 6 | 6.12244897959183 | 0.323026116213542 | [NAME], COL1A2, FAU, THBS1, RPS27A, THBS4 | 78 | 634 | 12983 | 1.5752244600825 | 1 | 0.980878800339989 | 99.4313311001417
SP_PIR_KEYWORDS | ribonucleoprotein | 3 | 3.06122448979591 | 0.411937504039362 | RPLP1, FAU, RPS27A | 98 | 279 | 19235 | 2.11048935703313 | 1 | 0.911705038444535 | 99.9015045813135
GOTERM_BP_FAT | GO:0006412~translation | 3 | 3.06122448979591 | 0.593186781691975 | RPLP1, FAU, RPS27A | 82 | 331 | 13528 | 1.49524721833321 | 1 | 0.997697138665114 | 99.9999475156124
GOTERM_CC_FAT | GO:0030529~ribonucleoprotein complex | 4 | 4.08163265306122 | 0.639308436418078 | RPLP1, FAU, HBA2, [NAME], RPS27A | 82 | 515 | 12782 | 1.21070329149893 | 1 | 0.984814442353634 | 99.9996969231666
GOTERM_CC_FAT | GO:0043232~intracellular non-membrane-bounded organelle | 11 | 11.2244897959183 | 0.978387011359205 | INTS6, [NAME], H3F3A, FAU, HBA2, SGCE, H3F3C, [NAME], C1QC, RPS27A, APC, RTN3 | 82 | 2596 | 12782 | 0.660500206696982 | 1 | 0.999986500973701 | 100
GOTERM_CC_FAT | GO:0043228~non-membrane-bounded organelle | 11 | 11.2244897959183 | 0.978387011359205 | INTS6, [NAME], H3F3A, FAU, HBA2, SGCE, H3F3C, [NAME], C1QC, RPS27A, APC, RTN3 | 82 | 2596 | 12782 | 0.660500206696982 | 1 | 0.999986500973701 | 100
Annotation Cluster 38 | Enrichment Score: 0.7356429281787438
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0044087~regulation of cellular component biogenesis | 4 | 4.08163265306122 | 0.0534416631212614 | S1PR1, THBS1, RPS27A, APC | 82 | 142 | 13528 | 4.64720027481964 | 1 | 0.769223996296935 | 58.6468660246567
GOTERM_BP_FAT | [NAME]negative regulation of apoptosis | 6 | 6.12244897959183 | 0.0610003339245246 | BTG2, THBS1, CD74, RPS27A, PROC, APC | 82 | 354 | 13528 | 2.79619677552707 | 1 | 0.771129268551848 | 63.6480882162083
GOTERM_BP_FAT | GO:0043069~negative regulation of programmed cell death | 6 | 6.12244897959183 | 0.0639937882925062 | BTG2, THBS1, CD74, RPS27A, PROC, APC | 82 | 359 | 13528 | 2.75725253074257 | 1 | 0.774321667552627 | 65.4671511153288
GOTERM_BP_FAT | GO:0060548~negative regulation of cell death | 6 | 6.12244897959183 | 0.0646023471471629 | BTG2, THBS1, CD74, RPS27A, PROC, APC | 82 | 360 | 13528 | 2.74959349593495 | 1 | 0.771078273662445 | 65.8263613420244
GOTERM_BP_FAT | GO:0051247~positive regulation of protein metabolic process | 4 | 4.08163265306122 | 0.178285013234795 | THBS1, ADIPOQ, RPS27A, APC | 82 | 243 | 13528 | 2.71564789721971 | 1 | 0.916020122289937 | 95.7447400196939
GOTERM_BP_FAT | GO:0033554~cellular response to stress | 4 | 4.08163265306122 | 0.664677937691167 | BTG2, PRDX6, THBS1, APC | 82 | 566 | 13528 | 1.16590536930104 | 1 | 0.999163999864931 | 99.9999976525603
GOTERM_BP_FAT | [NAME]~cell cycle process | 3 | 3.06122448979591 | 0.857796518959455 | THBS1, RPS27A, APC | 82 | 565 | 13528 | 0.875976688970429 | 1 | 0.999992382816312 | 99.9999999999975
GOTERM_BP_FAT | GO:0007049~cell cycle | 3 | 3.06122448979591 | 0.950928577116536 | THBS1, RPS27A, APC | 82 | 776 | 13528 | 0.637792305758109 | 1 | 0.999999976507985 | 100
Annotation Cluster 39 | Enrichment Score: 0.7351257188194636
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | Apoptosis | 5 | 5.10204081632653 | 0.126606688249715 | TSC22D3, UNC5A, CYCS, MGC29506, RTN3 | 98 | 381 | 19235 | 2.57579409716642 | 0.999999999999999 | 0.59826458185813 | 82.8836673887564
GOTERM_BP_FAT | [NAME]~apoptosis | 7 | 7.14285714285714 | 0.151464216388343 | TSC22D3, UNC5A, CYCS, MGC29506, THBS1, RPS27A, RTN3 | 82 | 602 | 13528 | 1.91832104367555 | 1 | 0.891200325678386 | 92.8683326509576
GOTERM_BP_FAT | GO:0012501~programmed cell death | 7 | 7.14285714285714 | 0.158995824405818 | TSC22D3, UNC5A, CYCS, MGC29506, THBS1, RPS27A, RTN3 | 82 | 611 | 13528 | 1.89006426889146 | 1 | 0.89553815039012 | 93.8207088801594
GOTERM_BP_FAT | GO:0008219~cell death | 7 | 7.14285714285714 | 0.260552710059099 | TSC22D3, UNC5A, CYCS, MGC29506, THBS1, RPS27A, RTN3 | 82 | 719 | 13528 | 1.60616031751416 | 1 | 0.963126109968156 | 99.2195420285387
GOTERM_BP_FAT | GO:0016265~death | 7 | 7.14285714285714 | 0.265658307350094 | TSC22D3, UNC5A, CYCS, MGC29506, THBS1, RPS27A, RTN3 | 82 | 724 | 13528 | 1.59506805012801 | 1 | 0.962455408206349 | 99.3018132398367
Annotation Cluster 40 | Enrichment Score: 0.7203737500488016
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | [NAME] | 12 | 12.2448979591836 | 0.000387351718239948 | GGT5, PAM, SDC1, S1PR1, CYP27A1, PECAM1, PTGFR, FCGR3B, CD74, IL3RA, MGST1, CD163 | 98 | 642 | 19235 | 3.66870112530993 | 0.0944214430775909 | 0.00897595074632473 | 0.503908110496187
SP_PIR_KEYWORDS | membrane | 36 | 36.734693877551 | 0.258338597466749 | PAM, [NAME], TLR2, AP3S1, GNG11, PLVAP, ABCA1, UQCRFS1, TENC1, CD74, RTN3, TSC22D3, C5ORF43, S1PR1, UNC5A, [NAME], LRRC70, SLC39A8, FCGR3B, SVEP1, SCD, GALNTL2, GOLIM4, PTGFR, CD163, GGT5, C20ORF30, MAGT1, SDC1, RDH10, CYP27A1, PECAM1, CYBRD1, SGCE, IL3RA, MGST1 | 98 | 6256 | 19235 | 1.12946265462706 | 1 | 0.817352166874207 | 97.9697133092753
SP_PIR_KEYWORDS | [NAME] | 29 | 29.5918367346938 | 0.282507885203956 | PAM, [NAME], TLR2, PLVAP, ABCA1, UQCRFS1, CD74, RTN3, C5ORF43, TSC22D3, S1PR1, UNC5A, LRRC70, SLC39A8, [NAME], SCD, GALNTL2, GOLIM4, PTGFR, CD163, C20ORF30, GGT5, MAGT1, SDC1, RDH10, PECAM1, CYBRD1, SGCE, IL3RA | 98 | 4973 | 19235 | 1.14457868407769 | 1 | 0.829774465322516 | 98.681928152157
UP_SEQ_FEATURE | transmembrane region | 28 | 28.5714285714285 | 0.350810851018645 | PAM, [NAME], TLR2, PLVAP, ABCA1, CD74, RTN3, C5ORF43, TSC22D3, S1PR1, UNC5A, LRRC70, SLC39A8, [NAME], SCD, GALNTL2, GOLIM4, PTGFR, CD163, C20ORF30, GGT5, MAGT1, SDC1, RDH10, PECAM1, CYBRD1, SGCE, IL3RA | 98 | 4911 | 19113 | 1.11196439479884 | 1 | 0.999545610170338 | 99.7945109256329
UP_SEQ_FEATURE | topological domain:Extracellular | 16 | 16.3265306122449 | 0.406278507672405 | TSPAN5, TLR2, PLVAP, ABCA1, PTGFR, CD74, CD163, GGT5, [NAME], S1PR1, UNC5A, PECAM1, SLC39A8, [NAME], SGCE, IL3RA | 98 | 2719 | 19113 | 1.14766082968678 | 1 | 0.999871033935143 | 99.9428176914061
UP_SEQ_FEATURE | topological domain:Cytoplasmic | 18 | 18.3673469387755 | 0.554958243702259 | PAM, TSPAN5, GALNTL2, TLR2, GOLIM4, PLVAP, PTGFR, CD74, CD163, GGT5, [NAME], S1PR1, UNC5A, PECAM1, SLC39A8, [NAME], SGCE, IL3RA | 98 | 3374 | 19113 | 1.04047155317372 | 1 | 0.999997694887114 | 99.999078680938
GOTERM_CC_FAT | GO:0016021~integral to membrane | 30 | 30.6122448979591 | 0.874730157647266 | PAM, [NAME], TLR2, PLVAP, ABCA1, UQCRFS1, CD74, RTN3, C5ORF43, TSC22D3, S1PR1, UNC5A, [NAME], LRRC70, SLC39A8, LY96, SCD, GALNTL2, GOLIM4, PTGFR, CD163, C20ORF30, GGT5, MAGT1, SDC1, RDH10, PECAM1, CYBRD1, SGCE, IL3RA | 82 | 5297 | 12782 | 0.882828292130382 | 1 | 0.998601554385589 | 99.9999999994266
GOTERM_CC_FAT | GO:0031224~intrinsic to membrane | 31 | 31.6326530612244 | 0.882375351173034 | PAM, [NAME], TLR2, PLVAP, ABCA1, UQCRFS1, CD74, RTN3, TSC22D3, C5ORF43, S1PR1, UNC5A, [NAME], LRRC70, SLC39A8, FCGR3B, LY96, SCD, GALNTL2, GOLIM4, PTGFR, CD163, C20ORF30, GGT5, MAGT1, SDC1, RDH10, PECAM1, CYBRD1, SGCE, IL3RA | 82 | 5485 | 12782 | 0.880988060564288 | 1 | 0.998721939879577 | 99.9999999997383
Annotation Cluster 41 | Enrichment Score: 0.6751222544912037
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0051338~regulation of transferase activity | 6 | 6.12244897959183 | 0.0721607995271135 | PPARG, FABP4, ZEB2, THBS1, CD74, APC | 82 | 372 | 13528 | 2.66089693154996 | 1 | 0.784627275509686 | 70.0055406255341
GOTERM_BP_FAT | GO:0043406~positive regulation of MAP kinase activity | 3 | 3.06122448979591 | 0.124558810200821 | ZEB2, THBS1, CD74 | 82 | 102 | 13528 | 4.85222381635581 | 1 | 0.855301876720963 | 88.219833674063
GOTERM_BP_FAT | GO:0042325~regulation of phosphorylation | 6 | 6.12244897959183 | 0.146893282602825 | FABP4, ZEB2, THBS1, ADIPOQ, CD74, APC | 82 | 466 | 13528 | 2.12414948183816 | 1 | 0.891844885179532 | 92.2249496073665
GOTERM_BP_FAT | GO:0045859~regulation of protein kinase activity | 5 | 5.10204081632653 | 0.152114185562208 | FABP4, ZEB2, THBS1, CD74, APC | 82 | 345 | 13528 | 2.39095086603039 | 1 | 0.889493656345103 | 92.9556553979215
GOTERM_BP_FAT | GO:0006928~cell motion | 6 | 6.12244897959183 | 0.155366664165945 | UNC5A, ZEB2, THBS1, RPS27A, THBS4, APC | 82 | 475 | 13528 | 2.08390243902439 | 1 | 0.892264796506452 | 93.3777627967857
GOTERM_BP_FAT | GO:0051174~regulation of phosphorus metabolic process | 6 | 6.12244897959183 | 0.165018070848719 | FABP4, ZEB2, THBS1, ADIPOQ, CD74, APC | 82 | 485 | 13528 | 2.04093537842594 | 1 | 0.902338747433668 | 94.4949735148456
GOTERM_BP_FAT | GO:0019220~regulation of phosphate metabolic process | 6 | 6.12244897959183 | 0.165018070848719 | FABP4, ZEB2, THBS1, ADIPOQ, CD74, APC | 82 | 485 | 13528 | 2.04093537842594 | 1 | 0.902338747433668 | 94.4949735148456
GOTERM_BP_FAT | GO:0043549~regulation of kinase activity | 5 | 5.10204081632653 | 0.165756796737956 | FABP4, ZEB2, THBS1, CD74, APC | 82 | 357 | 13528 | 2.31058276969324 | 1 | 0.900906682174156 | 94.5727576861153
GOTERM_BP_FAT | GO:0043085~positive regulation of catalytic activity | 6 | 6.12244897959183 | 0.200596793416294 | S1PR1, CYCS, ZEB2, THBS1, CD74, RPS27A | 82 | 520 | 13528 | 1.90356472795497 | 1 | 0.933165224153735 | 97.2665330113137
GOTERM_BP_FAT | GO:0043405~regulation of MAP kinase activity | 3 | 3.06122448979591 | 0.206709833762378 | ZEB2, THBS1, CD74 | 82 | 141 | 13528 | 3.51011935651271 | 1 | 0.935468260323835 | 97.5839036033189
GOTERM_BP_FAT | GO:0016477~cell migration | 4 | 4.08163265306122 | 0.229067437878549 | ZEB2, THBS1, THBS4, APC | 82 | 276 | 13528 | 2.39095086603039 | 1 | 0.94953989482857 | 98.4741896988849
GOTERM_BP_FAT | GO:0051094~positive regulation of developmental process | 4 | 4.08163265306122 | 0.232235670651399 | PPARG, THBS1, CD74, APC | 82 | 278 | 13528 | 2.37374978066327 | 1 | 0.95040224434187 | 98.5719398158843
GOTERM_BP_FAT | GO:0048870~cell motility | 4 | 4.08163265306122 | 0.278958581043386 | ZEB2, THBS1, THBS4, APC | 82 | 307 | 13528 | 2.14951934535632 | 1 | 0.964998054812644 | 99.4795866168422
GOTERM_BP_FAT | GO:0051674~localization of cell | 4 | 4.08163265306122 | 0.278958581043386 | ZEB2, THBS1, THBS4, APC | 82 | 307 | 13528 | 2.14951934535632 | 1 | 0.964998054812644 | 99.4795866168422
GOTERM_BP_FAT | GO:0045860~positive regulation of protein kinase activity | 3 | 3.06122448979591 | 0.3869219176364 | ZEB2, THBS1, CD74 | 82 | 223 | 13528 | 2.2194028218309 | 1 | 0.985347026337907 | 99.9616491626001
GOTERM_BP_FAT | GO:0033674~positive regulation of kinase activity | 3 | 3.06122448979591 | 0.403856811721439 | ZEB2, THBS1, CD74 | 82 | 231 | 13528 | 2.14254038644282 | 1 | 0.986892004104604 | 99.9755551042144
GOTERM_BP_FAT | GO:0051347~positive regulation of transferase activity | 3 | 3.06122448979591 | 0.4226471364425 | ZEB2, THBS1, CD74 | 82 | 240 | 13528 | 2.06219512195121 | 1 | 0.988579306318443 | 99.9853929888075
GOTERM_BP_FAT | GO:0010627~regulation of protein kinase cascade | 3 | 3.06122448979591 | 0.441137773130919 | ZEB2, ADIPOQ, APC | 82 | 249 | 13528 | 1.98765794886864 | 1 | 0.989037629755312 | 99.991344741979
Annotation Cluster 42 | Enrichment Score: 0.6515933034801892
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0032101~regulation of response to external stimulus | 6 | 6.12244897959183 | 0.00263100975945022 | S1PR1, PPARG, FABP4, THBS1, ADIPOQ, PROC | 82 | 159 | 13528 | 6.22549470777726 | 0.951412041040266 | 0.285407029745062 | 4.14714496380748
GOTERM_BP_FAT | GO:0044087~regulation of cellular component biogenesis | 4 | 4.08163265306122 | 0.0534416631212614 | S1PR1, THBS1, RPS27A, APC | 82 | 142 | 13528 | 4.64720027481964 | 1 | 0.769223996296935 | 58.6468660246567
GOTERM_BP_FAT | GO:0051338~regulation of transferase activity | 6 | 6.12244897959183 | 0.0721607995271135 | PPARG, FABP4, ZEB2, THBS1, CD74, APC | 82 | 372 | 13528 | 2.66089693154996 | 1 | 0.784627275509686 | 70.0055406255341
GOTERM_BP_FAT | GO:0043086~negative regulation of catalytic activity | 5 | 5.10204081632653 | 0.0844819382803629 | S1PR1, PPARG, FABP4, RPS27A, APC | 82 | 277 | 13528 | 2.97789909307035 | 1 | 0.799789874907222 | 75.8065390281116
GOTERM_BP_FAT | GO:0051348~negative regulation of transferase activity | 3 | 3.06122448979591 | 0.112762566430361 | PPARG, FABP4, APC | 82 | 96 | 13528 | 5.15548780487804 | 1 | 0.847639157236627 | 85.3914103944385
GOTERM_BP_FAT | [NAME]negative regulation of molecular function | 5 | 5.10204081632653 | 0.140014274752579 | S1PR1, PPARG, FABP4, RPS27A, APC | 82 | 334 | 13528 | 2.4696947568278 | 1 | 0.882088844853956 | 91.1533308387846
GOTERM_BP_FAT | GO:0048878~chemical homeostasis | 6 | 6.12244897959183 | 0.192233633034301 | CCL14, S1PR1, PPARG, FABP4, ABCA1, ADIPOQ | 82 | 512 | 13528 | 1.93330792682926 | 1 | 0.926260062563903 | 96.768661685281
GOTERM_BP_FAT | GO:0010604~positive regulation of macromolecule metabolic process | 6 | 6.12244897959183 | 0.589152431368671 | S1PR1, PPARG, THBS1, ADIPOQ, RPS27A, APC | 82 | 857 | 13528 | 1.15502177192133 | 1 | 0.99770833255752 | 99.9999384917844
GOTERM_BP_FAT | GO:0031328~positive regulation of cellular biosynthetic process | 5 | 5.10204081632653 | 0.59217681365913 | S1PR1, PPARG, ABCA1, THBS1, RPS27A | 82 | 685 | 13528 | 1.2042015310664 | 1 | 0.99774069485365 | 99.9999453810475
GOTERM_BP_FAT | GO:0009891~positive regulation of biosynthetic process | 5 | 5.10204081632653 | 0.603790250726211 | S1PR1, PPARG, ABCA1, THBS1, RPS27A | 82 | 695 | 13528 | 1.18687489033163 | 1 | 0.997928026520414 | 99.9999656740713
GOTERM_BP_FAT | GO:0045935~positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 4 | 4.08163265306122 | 0.728316887740315 | S1PR1, PPARG, ABCA1, RPS27A | 82 | 624 | 13528 | 1.05753595997498 | 1 | 0.999730696938456 | 99.999999920363
GOTERM_BP_FAT | GO:0051173~positive regulation of nitrogen compound metabolic process | 4 | 4.08163265306122 | 0.747991306948007 | S1PR1, PPARG, ABCA1, RPS27A | 82 | 644 | 13528 | 1.02469322829874 | 1 | 0.999824229713456 | 99.999999976219
GOTERM_BP_FAT | GO:0010557~positive regulation of macromolecule biosynthetic process | 4 | 4.08163265306122 | 0.757402592651059 | S1PR1, PPARG, THBS1, RPS27A | 82 | 654 | 13528 | 1.00902513612292 | 1 | 0.999854713758049 | 99.9999999871033
GOTERM_BP_FAT | GO:0045941~positive regulation of transcription | 3 | 3.06122448979591 | 0.857108721735304 | S1PR1, PPARG, RPS27A | 82 | 564 | 13528 | 0.877529839128178 | 1 | 0.999992630429817 | 99.9999999999974
GOTERM_BP_FAT | GO:0010628~positive regulation of gene expression | 3 | 3.06122448979591 | 0.868403120111435 | S1PR1, PPARG, RPS27A | 82 | 581 | 13528 | 0.85185340665799 | 1 | 0.999994582204541 | 99.9999999999993
Annotation Cluster 43 | Enrichment Score: 0.6487245757726953
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0008217~regulation of blood pressure | 3 | 3.06122448979591 | 0.120593504094412 | PPARG, COL1A2, ADIPOQ | 82 | 100 | 13528 | 4.94926829268292 | 1 | 0.852796306905917 | 87.3320391857217
GOTERM_BP_FAT | GO:0008015~blood circulation | 3 | 3.06122448979591 | 0.306373486624378 | PPARG, COL1A2, ADIPOQ | 82 | 186 | 13528 | 2.66089693154996 | 1 | 0.974057018535595 | 99.7209445365069
GOTERM_BP_FAT | GO:0003013~circulatory system process | 3 | 3.06122448979591 | 0.306373486624378 | PPARG, COL1A2, ADIPOQ | 82 | 186 | 13528 | 2.66089693154996 | 1 | 0.974057018535595 | 99.7209445365069
Annotation Cluster 44 | Enrichment Score: 0.6447313873503299
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0030155~regulation of cell adhesion | 5 | 5.10204081632653 | 0.00917880769927864 | S1PR1, COL8A1, THBS1, ADIPOQ, APC | 82 | 137 | 13528 | 6.02100765533202 | 0.999974730919081 | 0.506251302385549 | 13.7788059802895
GOTERM_BP_FAT | GO:0051129~negative regulation of cellular component organization | 4 | 4.08163265306122 | 0.0534416631212614 | S1PR1, THBS1, ADIPOQ, APC | 82 | 142 | 13528 | 4.64720027481964 | 1 | 0.769223996296935 | 58.6468660246567
GOTERM_BP_FAT | GO:0042981~regulation of apoptosis | 9 | 9.18367346938775 | 0.107522941629995 | BTG2, CYCS, TLR2, THBS1, ADIPOQ, CD74, RPS27A, PROC, APC | 82 | 804 | 13528 | 1.84674190025482 | 1 | 0.853457988063243 | 83.9408755634547
GOTERM_BP_FAT | GO:0043067~regulation of programmed cell death | 9 | 9.18367346938775 | 0.11212482564764 | BTG2, CYCS, TLR2, THBS1, ADIPOQ, CD74, RPS27A, PROC, APC | 82 | 812 | 13528 | 1.82854739877448 | 1 | 0.849858778241183 | 85.2216691540288
GOTERM_BP_FAT | GO:0010941~regulation of cell death | 9 | 9.18367346938775 | 0.113878430204008 | BTG2, CYCS, TLR2, THBS1, ADIPOQ, CD74, RPS27A, PROC, APC | 82 | 815 | 13528 | 1.82181654945383 | 1 | 0.846737210018683 | 85.6840186034038
GOTERM_BP_FAT | GO:0042325~regulation of phosphorylation | 6 | 6.12244897959183 | 0.146893282602825 | FABP4, ZEB2, THBS1, ADIPOQ, CD74, APC | 82 | 466 | 13528 | 2.12414948183816 | 1 | 0.891844885179532 | 92.2249496073665
GOTERM_BP_FAT | GO:0051174~regulation of phosphorus metabolic process | 6 | 6.12244897959183 | 0.165018070848719 | FABP4, ZEB2, THBS1, ADIPOQ, CD74, APC | 82 | 485 | 13528 | 2.04093537842594 | 1 | 0.902338747433668 | 94.4949735148456
GOTERM_BP_FAT | GO:0019220~regulation of phosphate metabolic process | 6 | 6.12244897959183 | 0.165018070848719 | FABP4, ZEB2, THBS1, ADIPOQ, CD74, APC | 82 | 485 | 13528 | 2.04093537842594 | 1 | 0.902338747433668 | 94.4949735148456
GOTERM_BP_FAT | GO:0051247~positive regulation of protein metabolic process | 4 | 4.08163265306122 | 0.178285013234795 | THBS1, ADIPOQ, RPS27A, APC | 82 | 243 | 13528 | 2.71564789721971 | 1 | 0.916020122289937 | 95.7447400196939
GOTERM_BP_FAT | GO:0010605~negative regulation of macromolecule metabolic process | 7 | 7.14285714285714 | 0.275949387732255 | PPARG, FABP4, ZEB2, THBS1, ADIPOQ, [NAME], RPS27A | 82 | 734 | 13528 | 1.57333687778294 | 1 | 0.965604826109649 | 99.443547474854
GOTERM_BP_FAT | GO:0010647~positive regulation of cell communication | 4 | 4.08163265306122 | 0.315020541089358 | ZEB2, THBS1, ADIPOQ, RPS27A | 82 | 329 | 13528 | 2.00578248943583 | 1 | 0.97635309234114 | 99.7719144145576
GOTERM_BP_FAT | GO:0009968~negative regulation of signal transduction | 3 | 3.06122448979591 | 0.382656316041348 | THBS1, ADIPOQ, APC | 82 | 221 | 13528 | 2.23948791524114 | 1 | 0.984926304185464 | 99.9571266055974
GOTERM_BP_FAT | GO:0032270~positive regulation of cellular protein metabolic process | 3 | 3.06122448979591 | 0.408057169400717 | THBS1, ADIPOQ, RPS27A | 82 | 233 | 13528 | 2.12414948183816 | 1 | 0.987246433016042 | 99.9781819005645
GOTERM_BP_FAT | [NAME]negative regulation of cell communication | 3 | 3.06122448979591 | 0.439098725661744 | THBS1, ADIPOQ, APC | 82 | 248 | 13528 | 1.99567269866247 | 1 | 0.98906238655756 | 99.9908228170125
GOTERM_BP_FAT | GO:0043065~positive regulation of apoptosis | 4 | 4.08163265306122 | 0.477951008977619 | TLR2, ADIPOQ, RPS27A, APC | 82 | 430 | 13528 | 1.53465683494044 | 1 | 0.991885867192571 | 99.9971060624569
GOTERM_BP_FAT | GO:0043068~positive regulation of programmed cell death | 4 | 4.08163265306122 | 0.482570251402833 | TLR2, ADIPOQ, RPS27A, APC | 82 | 433 | 13528 | 1.52402410860136 | 1 | 0.992161377575775 | 99.9974913968683
GOTERM_BP_FAT | GO:0010942~positive regulation of cell death | 4 | 4.08163265306122 | 0.485639439342845 | TLR2, ADIPOQ, RPS27A, APC | 82 | 435 | 13528 | 1.51701710120549 | 1 | 0.992017811254568 | 99.9977202256214
GOTERM_BP_FAT | GO:0031399~regulation of protein modification process | 3 | 3.06122448979591 | 0.530307121370244 | ZEB2, ADIPOQ, RPS27A | 82 | 295 | 13528 | 1.67771806531624 | 1 | 0.995275715168397 | 99.9994708566604
GOTERM_BP_FAT | GO:0009967~positive regulation of signal transduction | 3 | 3.06122448979591 | 0.530307121370244 | ZEB2, THBS1, ADIPOQ | 82 | 295 | 13528 | 1.67771806531624 | 1 | 0.995275715168397 | 99.9994708566604
GOTERM_BP_FAT | GO:0032268~regulation of cellular protein metabolic process | 4 | 4.08163265306122 | 0.54368781608929 | ZEB2, THBS1, ADIPOQ, RPS27A | 82 | 474 | 13528 | 1.39219923844808 | 1 | 0.996017080423551 | 99.9996675170459
GOTERM_BP_FAT | GO:0010604~positive regulation of macromolecule metabolic process | 6 | 6.12244897959183 | 0.589152431368671 | S1PR1, PPARG, THBS1, ADIPOQ, RPS27A, APC | 82 | 857 | 13528 | 1.15502177192133 | 1 | 0.99770833255752 | 99.9999384917844
Annotation Cluster 45 | Enrichment Score: 0.5991136701628277
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0042592~homeostatic process | 11 | 11.2244897959183 | 0.0138968397364089 | CTSK, CCL14, LIPA, S1PR1, PRDX6, PPARG, FABP4, ABCA1, ADIPOQ, FH, APC | 82 | 751 | 13528 | 2.41642038257932 | 0.999999894595652 | 0.518210638924555 | 20.14790797681
GOTERM_BP_FAT | GO:0048878~chemical homeostasis | 6 | 6.12244897959183 | 0.192233633034301 | CCL14, S1PR1, PPARG, FABP4, ABCA1, ADIPOQ | 82 | 512 | 13528 | 1.93330792682926 | 1 | 0.926260062563903 | 96.768661685281
GOTERM_BP_FAT | GO:0019725~cellular homeostasis | 5 | 5.10204081632653 | 0.304870026544461 | CCL14, S1PR1, PRDX6, ADIPOQ, APC | 82 | 466 | 13528 | 1.77012456819847 | 1 | 0.975139919671474 | 99.7110592935546
GOTERM_BP_FAT | GO:0006873~cellular ion homeostasis | 3 | 3.06122448979591 | 0.65994024150997 | CCL14, S1PR1, ADIPOQ | 82 | 374 | 13528 | 1.32333376809703 | 1 | 0.99912004066763 | 99.9999970585818
GOTERM_BP_FAT | GO:0055082~cellular chemical homeostasis | 3 | 3.06122448979591 | 0.668535925770574 | CCL14, S1PR1, ADIPOQ | 82 | 380 | 13528 | 1.30243902439024 | 1 | 0.999192607683722 | 99.9999980510797
GOTERM_BP_FAT | GO:0050801~ion homeostasis | 3 | 3.06122448979591 | 0.707666220894537 | CCL14, S1PR1, ADIPOQ | 82 | 409 | 13528 | 1.21009004711073 | 1 | 0.999590441983467 | 99.9999997413909
Annotation Cluster 46 | Enrichment Score: 0.5885118688967855
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0045596~negative regulation of cell differentiation | 7 | 7.14285714285714 | 0.00185353402892949 | LMO2, PPARG, ABCA1, C1QC, ADIPOQ, CD74, APC | 82 | 216 | 13528 | 5.34643179765131 | 0.881142684317388 | 0.262332167815126 | 2.93874723821506
GOTERM_BP_FAT | GO:0042325~regulation of phosphorylation | 6 | 6.12244897959183 | 0.146893282602825 | FABP4, ZEB2, THBS1, ADIPOQ, CD74, APC | 82 | 466 | 13528 | 2.12414948183816 | 1 | 0.891844885179532 | 92.2249496073665
GOTERM_BP_FAT | GO:0051174~regulation of phosphorus metabolic process | 6 | 6.12244897959183 | 0.165018070848719 | FABP4, ZEB2, THBS1, ADIPOQ, CD74, APC | 82 | 485 | 13528 | 2.04093537842594 | 1 | 0.902338747433668 | 94.4949735148456
GOTERM_BP_FAT | GO:0019220~regulation of phosphate metabolic process | 6 | 6.12244897959183 | 0.165018070848719 | FABP4, ZEB2, THBS1, ADIPOQ, CD74, APC | 82 | 485 | 13528 | 2.04093537842594 | 1 | 0.902338747433668 | 94.4949735148456
GOTERM_BP_FAT | GO:0065003~macromolecular complex assembly | 6 | 6.12244897959183 | 0.367422265061977 | H3F3A, ABCA1, H3F3C, ADIPOQ, CD74, APC | 82 | 665 | 13528 | 1.48850174216027 | 1 | 0.983547181489912 | 99.9365547451248
GOTERM_BP_FAT | GO:0043933~macromolecular complex subunit organization | 6 | 6.12244897959183 | 0.421515594779646 | H3F3A, ABCA1, H3F3C, ADIPOQ, CD74, APC | 82 | 710 | 13528 | 1.39416008244589 | 1 | 0.988759346075083 | 99.9849258577633
GOTERM_CC_FAT | GO:0044427~chromosomal part | 3 | 3.06122448979591 | 0.707114462078582 | H3F3A, H3F3C, APC | 82 | 386 | 12782 | 1.21148742575508 | 1 | 0.991261155717113 | 99.9999773733267
GOTERM_BP_FAT | GO:0051276~chromosome organization | 3 | 3.06122448979591 | 0.792443394154633 | H3F3A, H3F3C, APC | 82 | 485 | 13528 | 1.02046768921297 | 1 | 0.999938998926406 | 99.9999999989499
GOTERM_CC_FAT | GO:0005694~chromosome | 3 | 3.06122448979591 | 0.794260951143945 | H3F3A, H3F3C, APC | 82 | 460 | 12782 | 1.01659597030752 | 1 | 0.995700725736484 | 99.9999997224343
GOTERM_BP_FAT | GO:0006461~protein complex assembly | 3 | 3.06122448979591 | 0.810871089960534 | ADIPOQ, CD74, APC | 82 | 505 | 13528 | 0.980053127263945 | 1 | 0.999963693047601 | 99.9999999997644
GOTERM_BP_FAT | GO:0070271~protein complex biogenesis | 3 | 3.06122448979591 | 0.810871089960534 | ADIPOQ, CD74, APC | 82 | 505 | 13528 | 0.980053127263945 | 1 | 0.999963693047601 | 99.9999999997644
Annotation Cluster 47 | Enrichment Score: 0.5471342835610133
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0042802~identical protein binding | 7 | 7.14285714285714 | 0.178686420844043 | COL1A2, PLVAP, THBS1, ADIPOQ, [NAME], CD74, MGST1 | 78 | 640 | 12983 | 1.8205328525641 | 1 | 0.938901880082882 | 92.6356555256961
GOTERM_MF_FAT | GO:0042803~protein homodimerization activity | 4 | 4.08163265306122 | 0.318032757002573 | PLVAP, ADIPOQ, [NAME], MGST1 | 78 | 334 | 12983 | 1.99339781974512 | 1 | 0.984717792821254 | 99.3731663695349
GOTERM_MF_FAT | GO:0046983~protein dimerization activity | 5 | 5.10204081632653 | 0.401822031840939 | PPARG, PLVAP, ADIPOQ, [NAME], MGST1 | 78 | 542 | 12983 | 1.5355047781247 | 1 | 0.993476552819327 | 99.8896644896859
Annotation Cluster 48 | Enrichment Score: 0.5378981812509938
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
UP_SEQ_FEATURE | domain:EF-hand 2 | 3 | 3.06122448979591 | 0.235968509260606 | S100A1, [NAME], RCN1 | 98 | 182 | 19113 | 3.21479031172908 | 1 | 0.995456873631101 | 97.8820084341552
UP_SEQ_FEATURE | domain:EF-hand 1 | 3 | 3.06122448979591 | 0.235968509260606 | S100A1, [NAME], RCN1 | 98 | 182 | 19113 | 3.21479031172908 | 1 | 0.995456873631101 | 97.8820084341552
INTERPRO | [NAME]:EF-HAND 1 | 3 | 3.06122448979591 | 0.337444924036084 | S100A1, [NAME], RCN1 | 93 | 217 | 16659 | 2.47643823398245 | 1 | 0.998906071000187 | 99.5468704592525
INTERPRO | IPR011992:EF-Hand type | 3 | 3.06122448979591 | 0.375401736777472 | S100A1, [NAME], RCN1 | 93 | 236 | 16659 | 2.27706396938217 | 1 | 0.999348706499196 | 99.7909122555802
Annotation Cluster 49 | Enrichment Score: 0.5059080705263966
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0046872~metal ion binding | 30 | 30.6122448979591 | 0.166265236105391 | PAM, LMO2, PPARG, ZEB2, UQCRFS1, TENC1, PAK3, P4HA1, P4HA3, FASN, SLC39A8, THBS1, [NAME], RPS27A, THBS4, CRIP1, SVEP1, EGFL7, CRIP2, SCD, CYCS, GALNTL2, HBA2, HBA1, PHYH, PROC, CYP27A1, CYBRD1, SGCE, PPP2R3C, RCN1 | 78 | 4140 | 12983 | 1.20615013006317 | 1 | 0.943246072536114 | 91.0150013103938
GOTERM_MF_FAT | GO:0043169~cation binding | 30 | 30.6122448979591 | 0.181028939325175 | PAM, LMO2, PPARG, ZEB2, UQCRFS1, TENC1, PAK3, P4HA1, P4HA3, FASN, SLC39A8, THBS1, [NAME], RPS27A, THBS4, CRIP1, SVEP1, EGFL7, CRIP2, SCD, CYCS, GALNTL2, HBA2, HBA1, PHYH, PROC, CYP27A1, CYBRD1, SGCE, PPP2R3C, RCN1 | 78 | 4179 | 12983 | 1.19489388333609 | 1 | 0.932847765606929 | 92.9091782902045
GOTERM_MF_FAT | GO:0046914~transition metal ion binding | 21 | 21.4285714285714 | 0.200762246401831 | PAM, CRIP1, LMO2, CRIP2, SCD, CYCS, PPARG, GALNTL2, HBA2, ZEB2, [NAME], UQCRFS1, TENC1, PHYH, CYP27A1, P4HA1, P4HA3, SLC39A8, CYBRD1, FASN, [NAME], S100A1 | 78 | 2785 | 12983 | 1.25508907609446 | 1 | 0.944583956774972 | 94.8674708767369
GOTERM_MF_FAT | GO:0043167~ion binding | 30 | 30.6122448979591 | 0.206017524803088 | PAM, LMO2, PPARG, ZEB2, UQCRFS1, TENC1, PAK3, P4HA1, P4HA3, FASN, SLC39A8, THBS1, [NAME], RPS27A, THBS4, CRIP1, SVEP1, EGFL7, CRIP2, SCD, CYCS, GALNTL2, HBA2, HBA1, PHYH, PROC, CYP27A1, CYBRD1, SGCE, PPP2R3C, RCN1 | 78 | 4241 | 12983 | 1.17742549834037 | 1 | 0.942072788290938 | 95.2971026153637
SP_PIR_KEYWORDS | metal-binding | 18 | 18.3673469387755 | 0.325641034376744 | PAM, CRIP1, LMO2, CRIP2, CYCS, PPARG, HBA2, ZEB2, [NAME], UQCRFS1, TENC1, PHYH, CYP27A1, P4HA1, PAK3, P4HA3, CYBRD1, [NAME], S100A1 | 98 | 2972 | 19235 | 1.18874804295877 | 1 | 0.866978262715839 | 99.4127274343242
SP_PIR_KEYWORDS | zinc | 10 | 10.204081632653 | 0.788188605499783 | PAM, CRIP1, LMO2, CRIP2, PPARG, SLC39A8, ZEB2, TENC1, [NAME], RPS27A | 98 | 2189 | 19235 | 0.896644633184475 | 1 | 0.997100003738201 | 99.999999837531
GOTERM_MF_FAT | GO:0008270~zinc ion binding | 11 | 11.2244897959183 | 0.899784601945315 | PAM, CRIP1, LMO2, CRIP2, PPARG, SLC39A8, FASN, ZEB2, TENC1, [NAME], RPS27A | 78 | 2311 | 12983 | 0.792269968600561 | 1 | 0.999999998640768 | 99.9999999999942
Annotation Cluster 50 | Enrichment Score: 0.4970922441052143
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0009952~anterior/posterior pattern formation | 3 | 3.06122448979591 | 0.204522911588159 | BTG2, ZEB2, APC | 82 | 140 | 13528 | 3.53519163763066 | 1 | 0.935185433721658 | 97.4745623506143
GOTERM_BP_FAT | GO:0003002~regionalization | 3 | 3.06122448979591 | 0.330624602383037 | BTG2, ZEB2, APC | 82 | 197 | 13528 | 2.5123189302959 | 1 | 0.97850979434802 | 99.8425303290454
GOTERM_BP_FAT | GO:0007389~pattern specification process | 3 | 3.06122448979591 | 0.477140338011467 | BTG2, ZEB2, APC | 82 | 267 | 13528 | 1.85365853658536 | 1 | 0.992044101952459 | 99.9970329596991
Annotation Cluster 51 | Enrichment Score: 0.4544661702808596
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | [NAME]lipid binding | 8 | 8.16326530612245 | 0.0171429154407624 | ALDH1A1, SNX9, S1PR1, PPARG, SNX2, FABP4, ABCA1, TENC1 | 78 | 450 | 12983 | 2.95908831908831 | 0.992633422215419 | 0.388035009067126 | 20.4779155899103
GOTERM_MF_FAT | GO:0005543~phospholipid binding | 3 | 3.06122448979591 | 0.282697686606719 | SNX9, SNX2, ABCA1 | 78 | 177 | 12983 | 2.82116471099521 | 1 | 0.977050282192396 | 98.7757543591212
GOTERM_BP_FAT | GO:0006886~intracellular protein transport | 4 | 4.08163265306122 | 0.388877644794315 | SNX9, SNX2, AP3S1, CD74 | 82 | 374 | 13528 | 1.76444502412938 | 1 | 0.985286197390563 | 99.9635694833121
GOTERM_BP_FAT | GO:0034613~cellular protein localization | 4 | 4.08163265306122 | 0.448290423632787 | SNX9, SNX2, AP3S1, CD74 | 82 | 411 | 13528 | 1.60560204142187 | 1 | 0.989768069500166 | 99.992963795679
GOTERM_BP_FAT | [NAME]~cellular macromolecule localization | 4 | 4.08163265306122 | 0.453017794902845 | SNX9, SNX2, AP3S1, CD74 | 82 | 414 | 13528 | 1.59396724402026 | 1 | 0.989816379845693 | 99.9938729499925
GOTERM_BP_FAT | GO:0016192~vesicle-mediated transport | 5 | 5.10204081632653 | 0.454674191915378 | SNX2, AP3S1, ABCA1, THBS1, RTN3 | 82 | 576 | 13528 | 1.43207994579945 | 1 | 0.98974205941843 | 99.9941645420423
GOTERM_BP_FAT | GO:0015031~protein transport | 6 | 6.12244897959183 | 0.483085375435687 | SNX9, PPARG, SNX2, AP3S1, ABCA1, CD74 | 82 | 762 | 13528 | 1.29902054926061 | 1 | 0.991974183945253 | 99.997531249384
GOTERM_BP_FAT | GO:0045184~establishment of protein localization | 6 | 6.12244897959183 | 0.491229594882625 | SNX9, PPARG, SNX2, AP3S1, ABCA1, CD74 | 82 | 769 | 13528 | 1.28719591487202 | 1 | 0.99239584826198 | 99.9980875472546
GOTERM_BP_FAT | GO:0046907~intracellular transport | 5 | 5.10204081632653 | 0.558664748574852 | SNX9, SNX2, AP3S1, ABCA1, CD74 | 82 | 657 | 13528 | 1.25552214426253 | 1 | 0.996738778287044 | 99.9998055758142
GOTERM_BP_FAT | GO:0008104~protein localization | 6 | 6.12244897959183 | 0.615131240975056 | SNX9, PPARG, SNX2, AP3S1, ABCA1, CD74 | 82 | 882 | 13528 | 1.12228305956528 | 1 | 0.99809606969593 | 99.9999784799019
SP_PIR_KEYWORDS | protein transport | 3 | 3.06122448979591 | 0.706073184467151 | SNX9, SNX2, AP3S1 | 98 | 485 | 19235 | 1.21407532084998 | 1 | 0.99134209749198 | 99.9999883547747
Annotation Cluster 52 | Enrichment Score: 0.43268288541010974
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0006928~cell motion | 6 | 6.12244897959183 | 0.155366664165945 | UNC5A, ZEB2, THBS1, RPS27A, THBS4, APC | 82 | 475 | 13528 | 2.08390243902439 | 1 | 0.892264796506452 | 93.3777627967857
GOTERM_BP_FAT | GO:0030182~neuron differentiation | 5 | 5.10204081632653 | 0.267252279874081 | S1PR1, BTG2, UNC5A, RPS27A, APC | 82 | 438 | 13528 | 1.8832832163938 | 1 | 0.962183122023213 | 99.3257839918226
GOTERM_BP_FAT | GO:0007409~axonogenesis | 3 | 3.06122448979591 | 0.321828190270718 | UNC5A, RPS27A, APC | 82 | 193 | 13528 | 2.56438771641602 | 1 | 0.977863384237883 | 99.8057520660409
GOTERM_BP_FAT | GO:0048667~cell morphogenesis involved in neuron differentiation | 3 | 3.06122448979591 | 0.356819951911428 | UNC5A, RPS27A, APC | 82 | 209 | 13528 | 2.3680709534368 | 1 | 0.983191439943809 | 99.917118513185
GOTERM_BP_FAT | GO:0000902~cell morphogenesis | 4 | 4.08163265306122 | 0.359435258746442 | LIPA, UNC5A, RPS27A, APC | 82 | 356 | 13528 | 1.85365853658536 | 1 | 0.983270811770092 | 99.9223738998721
GOTERM_BP_FAT | GO:0048812~neuron projection morphogenesis | 3 | 3.06122448979591 | 0.365476003784736 | UNC5A, RPS27A, APC | 82 | 213 | 13528 | 2.32360013740982 | 1 | 0.983622227998999 | 99.9333425048137
GOTERM_BP_FAT | [NAME]~cell projection organization | 4 | 4.08163265306122 | 0.379090808070106 | UNC5A, RPS27A, THBS4, APC | 82 | 368 | 13528 | 1.79321314952279 | 1 | 0.98560835502071 | 99.9529673875203
GOTERM_BP_FAT | GO:0032989~cellular component morphogenesis | 4 | 4.08163265306122 | 0.426033287499036 | LIPA, UNC5A, RPS27A, APC | 82 | 397 | 13528 | 1.6622227683234 | 1 | 0.988761253469031 | 99.9867110898564
GOTERM_BP_FAT | GO:0000904~cell morphogenesis involved in differentiation | 3 | 3.06122448979591 | 0.430903494055876 | UNC5A, RPS27A, APC | 82 | 244 | 13528 | 2.02838864454218 | 1 | 0.988823965217901 | 99.9884124989549
GOTERM_BP_FAT | GO:0048858~cell projection morphogenesis | 3 | 3.06122448979591 | 0.432958103515632 | UNC5A, RPS27A, APC | 82 | 245 | 13528 | 2.02010950721752 | 1 | 0.988797584994743 | 99.9890670932825
GOTERM_BP_FAT | GO:0032990~cell part morphogenesis | 3 | 3.06122448979591 | 0.455298863914467 | UNC5A, RPS27A, APC | 82 | 256 | 13528 | 1.93330792682926 | 1 | 0.989520878391816 | 99.9942710897958
GOTERM_BP_FAT | [NAME]neuron projection development | 3 | 3.06122448979591 | 0.455298863914467 | UNC5A, RPS27A, APC | 82 | 256 | 13528 | 1.93330792682926 | 1 | 0.989520878391816 | 99.9942710897958
GOTERM_BP_FAT | [NAME] development | 3 | 3.06122448979591 | 0.606295943788054 | UNC5A, RPS27A, APC | 82 | 339 | 13528 | 1.45996114828404 | 1 | 0.997866700101199 | 99.9999690026667
Annotation Cluster 53 | Enrichment Score: 0.39601497779721456
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0005912~adherens junction | 3 | 3.06122448979591 | 0.257627104369117 | SDC1, TENC1, APC | 82 | 155 | 12782 | 3.01699449252557 | 1 | 0.871702950874056 | 97.5574367932214
GOTERM_CC_FAT | GO:0070161~anchoring junction | 3 | 3.06122448979591 | 0.297604380511082 | SDC1, TENC1, APC | 82 | 172 | 12782 | 2.71880317640385 | 1 | 0.904725782525302 | 98.7745830504939
GOTERM_CC_FAT | GO:0030054~cell junction | 3 | 3.06122448979591 | 0.845910069968678 | SDC1, TENC1, APC | 82 | 518 | 12782 | 0.902768622280817 | 1 | 0.997560276947545 | 99.9999999924316
Annotation Cluster 54 | Enrichment Score: 0.3388759114191138
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0010324~membrane invagination | 3 | 3.06122448979591 | 0.38051894809625 | SNX2, ABCA1, THBS1 | 82 | 220 | 13528 | 2.24966740576496 | 1 | 0.985430404277889 | 99.9546768008759
GOTERM_BP_FAT | GO:0006897~endocytosis | 3 | 3.06122448979591 | 0.38051894809625 | SNX2, ABCA1, THBS1 | 82 | 220 | 13528 | 2.24966740576496 | 1 | 0.985430404277889 | 99.9546768008759
GOTERM_BP_FAT | GO:0016192~vesicle-mediated transport | 5 | 5.10204081632653 | 0.454674191915378 | SNX2, AP3S1, ABCA1, THBS1, RTN3 | 82 | 576 | 13528 | 1.43207994579945 | 1 | 0.98974205941843 | 99.9941645420423
GOTERM_BP_FAT | [NAME]~membrane organization | 3 | 3.06122448979591 | 0.669951672551926 | SNX2, ABCA1, THBS1 | 82 | 381 | 13528 | 1.29902054926061 | 1 | 0.999182587253374 | 99.9999981806884
Annotation Cluster 55 | Enrichment Score: 0.29416212983996864
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0009055~electron carrier activity | 4 | 4.08163265306122 | 0.143489472609339 | CYP27A1, CYCS, UQCRFS1, PHYH | 78 | 221 | 12983 | 3.01264647870982 | 1 | 0.936025703572845 | 87.1583261209865
SP_PIR_KEYWORDS | mitochondrion | 6 | 6.12244897959183 | 0.410230620046297 | TSC22D3, CYP27A1, CYCS, UQCRFS1, MGST1, FH | 98 | 832 | 19235 | 1.41544839089481 | 1 | 0.914369205560676 | 99.8977109270677
GOTERM_CC_FAT | GO:0031980~mitochondrial lumen | 3 | 3.06122448979591 | 0.42318724702611 | CYP27A1, CYCS, FH | 82 | 227 | 12782 | 2.06006231868486 | 1 | 0.951885286059442 | 99.8947313269251
GOTERM_CC_FAT | GO:0005759~mitochondrial matrix | 3 | 3.06122448979591 | 0.42318724702611 | CYP27A1, CYCS, FH | 82 | 227 | 12782 | 2.06006231868486 | 1 | 0.951885286059442 | 99.8947313269251
SP_PIR_KEYWORDS | transit peptide | 4 | 4.08163265306122 | 0.431957774194408 | CYP27A1, [NAME], PHYH, FH | 98 | 476 | 19235 | 1.64937403532841 | 1 | 0.921138079673117 | 99.9373002462881
GOTERM_CC_FAT | GO:0005740~mitochondrial envelope | 4 | 4.08163265306122 | 0.49854697766087 | CYP27A1, CYCS, UQCRFS1, MGST1 | 82 | 419 | 12782 | 1.48809593107864 | 1 | 0.967150854740374 | 99.9816082025783
GOTERM_CC_FAT | GO:0044429~mitochondrial part | 5 | 5.10204081632653 | 0.524738976882896 | CYP27A1, CYCS, UQCRFS1, MGST1, FH | 82 | 595 | 12782 | 1.30989956958393 | 1 | 0.969854851842252 | 99.9905743482491
GOTERM_CC_FAT | GO:0031967~[NAME] | 5 | 5.10204081632653 | 0.557700109862796 | CYP27A1, SCD, CYCS, UQCRFS1, MGST1 | 82 | 620 | 12782 | 1.25708103855232 | 1 | 0.976450348337933 | 99.996151048608
GOTERM_CC_FAT | GO:0031975~envelope | 5 | 5.10204081632653 | 0.560286262283455 | CYP27A1, SCD, CYCS, UQCRFS1, MGST1 | 82 | 622 | 12782 | 1.25303897733511 | 1 | 0.974972680393781 | 99.9964222725506
GOTERM_CC_FAT | [NAME]mitochondrial inner membrane | 3 | 3.06122448979591 | 0.581263950670153 | CYP27A1, UQCRFS1, MGST1 | 82 | 306 | 12782 | 1.52821616451458 | 1 | 0.9780369371466 | 99.9980543349941
GOTERM_CC_FAT | GO:0019866~organelle inner membrane | 3 | 3.06122448979591 | 0.621031723276216 | CYP27A1, UQCRFS1, MGST1 | 82 | 329 | 12782 | 1.4213803840166 | 1 | 0.982940583975181 | 99.9994388906571
UP_SEQ_FEATURE | transit peptide:Mitochondrion | 3 | 3.06122448979591 | 0.689499037465859 | CYP27A1, UQCRFS1, FH | 98 | 467 | 19113 | 1.25287331206572 | 1 | 0.999999976822252 | 99.9999946869203
GOTERM_CC_FAT | [NAME]~mitochondrion | 7 | 7.14285714285714 | 0.696676730444164 | TSC22D3, CYP27A1, P4HA1, CYCS, UQCRFS1, MGST1, FH | 82 | 1087 | 12782 | 1.00381448156707 | 1 | 0.99174286692422 | 99.9999649956253
GOTERM_CC_FAT | GO:0031966~mitochondrial membrane | 3 | 3.06122448979591 | 0.7178190584801 | CYP27A1, UQCRFS1, MGST1 | 82 | 394 | 12782 | 1.18688869629813 | 1 | 0.991670396080194 | 99.9999857725787
GOTERM_CC_FAT | GO:0031090~[NAME] membrane | 6 | 6.12244897959183 | 0.834999580157817 | MAGT1, CYP27A1, SCD, PECAM1, UQCRFS1, MGST1 | 82 | 1096 | 12782 | 0.853346982374933 | 1 | 0.997244199950786 | 99.9999999822489
Annotation Cluster 56 | Enrichment Score: 0.28834197233502684
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0044459~plasma membrane part | 17 | 17.3469387755102 | 0.315864374159887 | TLR2, AP3S1, PLVAP, GNG11, ABCA1, PTGFR, TENC1, CD74, CD163, SDC1, S1PR1, CYBRD1, [NAME], SGCE, THBS1, IGFBP2, APC | 82 | 2203 | 12782 | 1.20287191523753 | 1 | 0.905891839164091 | 99.1174541495835
GOTERM_CC_FAT | GO:0005886~plasma membrane | 27 | 27.5510204081632 | 0.346025023402473 | SNX9, TLR2, AP3S1, GNG11, PLVAP, ABCA1, TENC1, CD74, S1PR1, UNC5A, COL6A3, [NAME], THBS1, FCGR3B, APC, LGALS3, LY96, PTGFR, PROC, CD163, GGT5, [NAME], PECAM1, COL1A2, CYBRD1, SGCE, IGFBP2 | 82 | 3777 | 12782 | 1.11429899843081 | 1 | 0.916571954533222 | 99.4967994738628
UP_SEQ_FEATURE | topological domain:Extracellular | 16 | 16.3265306122449 | 0.406278507672405 | TSPAN5, TLR2, PLVAP, ABCA1, PTGFR, CD74, CD163, GGT5, [NAME], S1PR1, UNC5A, PECAM1, SLC39A8, [NAME], SGCE, IL3RA | 98 | 2719 | 19113 | 1.14766082968678 | 1 | 0.999871033935143 | 99.9428176914061
SP_PIR_KEYWORDS | cell membrane | 11 | 11.2244897959183 | 0.680481909054358 | S1PR1, UNC5A, [NAME], PLVAP, GNG11, SGCE, PTGFR, TENC1, FCGR3B, CD74, CD163 | 98 | 2194 | 19235 | 0.984061354715085 | 1 | 0.991004076776764 | 99.9999654133685
GOTERM_CC_FAT | GO:0005887~integral to plasma membrane | 7 | 7.14285714285714 | 0.775823515296737 | SDC1, [NAME], TLR2, SGCE, ABCA1, PTGFR, CD163 | 82 | 1188 | 12782 | 0.91847335140018 | 1 | 0.995683144040251 | 99.999999191236
GOTERM_CC_FAT | GO:0031226~intrinsic to plasma membrane | 7 | 7.14285714285714 | 0.794212362199014 | SDC1, [NAME], TLR2, SGCE, ABCA1, PTGFR, CD163 | 82 | 1215 | 12782 | 0.898062832480176 | 1 | 0.996103040932247 | 99.9999997216164
Annotation Cluster 57 | Enrichment Score: 0.26248657429009953
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0051338~regulation of transferase activity | 6 | 6.12244897959183 | 0.0721607995271135 | PPARG, FABP4, ZEB2, THBS1, CD74, APC | 82 | 372 | 13528 | 2.66089693154996 | 1 | 0.784627275509686 | 70.0055406255341
GOTERM_BP_FAT | GO:0010605~negative regulation of macromolecule metabolic process | 7 | 7.14285714285714 | 0.275949387732255 | PPARG, FABP4, ZEB2, THBS1, ADIPOQ, [NAME], RPS27A | 82 | 734 | 13528 | 1.57333687778294 | 1 | 0.965604826109649 | 99.443547474854
GOTERM_BP_FAT | GO:0060429~epithelium development | 3 | 3.06122448979591 | 0.395415475490189 | S1PR1, PPARG, ZEB2 | 82 | 227 | 13528 | 2.18029440206296 | 1 | 0.986145996088933 | 99.9693546361791
GOTERM_BP_FAT | GO:0010558~negative regulation of macromolecule biosynthetic process | 5 | 5.10204081632653 | 0.415578950885277 | PPARG, FABP4, ZEB2, ADIPOQ, S100A1 | 82 | 547 | 13528 | 1.50800374548535 | 1 | 0.988158943056983 | 99.9822367031281
GOTERM_BP_FAT | [NAME] regulation of cellular biosynthetic process | 5 | 5.10204081632653 | 0.434536966744656 | PPARG, FABP4, ZEB2, ADIPOQ, S100A1 | 82 | 561 | 13528 | 1.47037085344115 | 1 | 0.988698112543399 | 99.9895463763926
GOTERM_BP_FAT | GO:0009890~negative regulation of biosynthetic process | 5 | 5.10204081632653 | 0.450663228176465 | PPARG, FABP4, ZEB2, ADIPOQ, S100A1 | 82 | 573 | 13528 | 1.4395777465628 | 1 | 0.98979298791185 | 99.9934348649752
GOTERM_BP_FAT | GO:0016481~negative regulation of transcription | 4 | 4.08163265306122 | 0.521785743737061 | PPARG, FABP4, ZEB2, S100A1 | 82 | 459 | 13528 | 1.4376959455869 | 1 | 0.994805194814637 | 99.9992934944674
GOTERM_BP_FAT | [NAME]negative regulation of gene expression | 4 | 4.08163265306122 | 0.585748714661198 | PPARG, FABP4, ZEB2, S100A1 | 82 | 504 | 13528 | 1.3093302361595 | 1 | 0.997745106661846 | 99.9999297669887
GOTERM_BP_FAT | GO:0045934~negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 4 | 4.08163265306122 | 0.596552065925213 | PPARG, FABP4, ZEB2, S100A1 | 82 | 512 | 13528 | 1.28887195121951 | 1 | 0.99774329937454 | 99.9999540770882
GOTERM_BP_FAT | [NAME]~negative regulation of nitrogen compound metabolic process | 4 | 4.08163265306122 | 0.605857686231093 | PPARG, FABP4, ZEB2, S100A1 | 82 | 519 | 13528 | 1.27148832181963 | 1 | 0.997925950290267 | 99.9999684432287
GOTERM_BP_FAT | GO:0006357~regulation of transcription from RNA polymerase II promoter | 3 | 3.06122448979591 | 0.936708795581408 | S1PR1, PPARG, S100A1 | 82 | 727 | 13528 | 0.680779682624886 | 1 | 0.999999912240686 | 100
GOTERM_MF_FAT | GO:0003700~transcription factor activity | 3 | 3.06122448979591 | 0.982452148247428 | TSC22D3, PPARG, ZEB2 | 78 | 975 | 12983 | 0.51214990138067 | 1 | 0.999999999999997 | 100
GOTERM_MF_FAT | GO:0030528~transcription regulator activity | 5 | 5.10204081632653 | 0.983624206397574 | TSC22D3, PPARG, FABP4, ZEB2, RPS27A | 78 | 1512 | 12983 | 0.550425654592321 | 1 | 0.999999999999996 | 100
GOTERM_BP_FAT | GO:0045449~regulation of transcription | 9 | 9.18367346938775 | 0.992864576468267 | TSC22D3, S1PR1, BTG2, PPARG, TLR2, FABP4, ZEB2, [NAME], RPS27A | 82 | 2601 | 13528 | 0.570849860747742 | 1 | 0.999999999999522 | 100
GOTERM_BP_FAT | GO:0006355~regulation of transcription, DNA-dependent | 5 | 5.10204081632653 | 0.995742251707199 | TSC22D3, S1PR1, PPARG, ZEB2, S100A1 | 82 | 1773 | 13528 | 0.465244246351092 | 1 | 0.999999999999971 | 100
GOTERM_BP_FAT | GO:0051252~regulation of RNA metabolic process | 5 | 5.10204081632653 | 0.996536682130105 | TSC22D3, S1PR1, PPARG, ZEB2, S100A1 | 82 | 1813 | 13528 | 0.454979618742685 | 1 | 0.999999999999989 | 100
Annotation Cluster 58 | Enrichment Score: 0.24894891363289456
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0043233~organelle lumen | 13 | 13.2653061224489 | 0.489093269580548 | CYCS, [NAME], C1QC, RTN3, CYP27A1, P4HA1, INTS6, P4HA3, THBS1, RCN1, RPS27A, FH, THBS4 | 82 | 1820 | 12782 | 1.11341463414634 | 1 | 0.96698719260058 | 99.9767887528085
GOTERM_CC_FAT | GO:0031974~membrane-enclosed lumen | 13 | 13.2653061224489 | 0.518116072931981 | CYCS, [NAME], C1QC, RTN3, CYP27A1, P4HA1, INTS6, P4HA3, THBS1, RCN1, RPS27A, FH, THBS4 | 82 | 1856 | 12782 | 1.0918182296047 | 1 | 0.970474498874415 | 99.9888003637653
GOTERM_CC_FAT | GO:0070013~intracellular organelle lumen | 11 | 11.2244897959183 | 0.706861792113821 | CYP27A1, P4HA1, INTS6, P4HA3, CYCS, GOLIM4, C1QC, RPS27A, [NAME], FH, RTN3 | 82 | 1779 | 12782 | 0.963832791784916 | 1 | 0.992039910836365 | 99.9999771288875
Annotation Cluster 59 | Enrichment Score: 0.1986642379976956
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0005792~microsome | 3 | 3.06122448979591 | 0.444891961247407 | SNX9, RDH10, MGST1 | 82 | 237 | 12782 | 1.97313985798085 | 1 | 0.957383334684111 | 99.934726766826
GOTERM_CC_FAT | GO:0042598~vesicular fraction | 3 | 3.06122448979591 | 0.459820226802815 | SNX9, RDH10, MGST1 | 82 | 244 | 12782 | 1.91653338664534 | 1 | 0.959741087608999 | 99.9535261078648
GOTERM_CC_FAT | GO:0005624~membrane fraction | 5 | 5.10204081632653 | 0.762430897178234 | SNX9, [NAME], [NAME], ABCA1, MGST1 | 82 | 809 | 12782 | 0.963399559829961 | 1 | 0.995178075351137 | 99.9999983333931
GOTERM_CC_FAT | GO:0005626~insoluble fraction | 5 | 5.10204081632653 | 0.787167827976242 | SNX9, [NAME], [NAME], ABCA1, MGST1 | 82 | 839 | 12782 | 0.928951423006482 | 1 | 0.996033974943895 | 99.9999995765562
GOTERM_CC_FAT | [NAME]cell fraction | 6 | 6.12244897959183 | 0.827119684488592 | SNX9, [NAME], [NAME], FABP4, ABCA1, MGST1 | 82 | 1083 | 12782 | 0.863590297952841 | 1 | 0.997092413831018 | 99.9999999682541
Annotation Cluster 60 | Enrichment Score: 0.16569582793580295
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
INTERPRO | IPR003599:Immunoglobulin subtype | 3 | 3.06122448979591 | 0.54689178266385 | UNC5A, PECAM1, FCGR3B | 93 | 330 | 16659 | 1.62844574780058 | 1 | 0.999991319823872 | 99.9968896336973
SMART | SM00409:IG | 3 | 3.06122448979591 | 0.628625080705728 | UNC5A, PECAM1, FCGR3B | 59 | 330 | 9079 | 1.39892141756548 | 1 | 0.999883357240149 | 99.995737028423
SP_PIR_KEYWORDS | Immunoglobulin domain | 3 | 3.06122448979591 | 0.689515723760081 | UNC5A, PECAM1, FCGR3B | 98 | 470 | 19235 | 1.25282240555796 | 1 | 0.991372062476138 | 99.9999762046924
INTERPRO | IPR007110:Immunoglobulin-like | 3 | 3.06122448979591 | 0.768723715601203 | UNC5A, PECAM1, FCGR3B | 93 | 501 | 16659 | 1.07262893567703 | 1 | 0.999999998646986 | 99.9999995389305
INTERPRO | IPR013783:Immunoglobulin-like fold | 3 | 3.06122448979591 | 0.814541665318592 | UNC5A, PECAM1, FCGR3B | 93 | 553 | 16659 | 0.971766901942483 | 1 | 0.999999999798505 | 99.9999999744895
Annotation Cluster 61 | Enrichment Score: 0.07406846377564871
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | DNA binding | 3 | 3.06122448979591 | 0.513786164250616 | PPARG, H3F3A, RBMS1 | 98 | 340 | 19235 | 1.73184273709483 | 1 | 0.956232774242722 | 99.9917508365365
SP_PIR_KEYWORDS | dna-binding | 5 | 5.10204081632653 | 0.987791464857858 | PPARG, H3F3A, ZEB2, H3F3C, RBMS1 | 98 | 1868 | 19235 | 0.525362714679019 | 1 | 0.999999705459551 | 100
GOTERM_MF_FAT | GO:0003677~DNA binding | 7 | 7.14285714285714 | 0.996706885825981 | TSC22D3, LMO2, PPARG, H3F3A, ZEB2, H3F3C, RBMS1 | 78 | 2331 | 12983 | 0.499845999845999 | 1 | 1 | 100
SP_PIR_KEYWORDS | nucleus | 11 | 11.2244897959183 | 0.999334801964503 | LMO2, LGALS3, INTS6, PPARG, H3F3A, FABP4, ZEB2, H3F3C, PPP2R3C, RPS27A, RBMS1 | 98 | 4283 | 19235 | 0.504093068467172 | 1 | 0.999999999972625 | 100
Annotation Cluster 62 | Enrichment Score: 0.05826876293699364
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0006468~protein amino acid phosphorylation | 4 | 4.08163265306122 | 0.769220067426625 | PAK3, GMFG, THBS1, CD74 | 82 | 667 | 13528 | 0.989358979047061 | 1 | 0.999888214444721 | 99.9999999942219
GOTERM_BP_FAT | GO:0016310~phosphorylation | 4 | 4.08163265306122 | 0.865289400899654 | PAK3, GMFG, THBS1, CD74 | 82 | 800 | 13528 | 0.824878048780487 | 1 | 0.999994148133719 | 99.9999999999989
GOTERM_BP_FAT | GO:0006793~phosphorus metabolic process | 4 | 4.08163265306122 | 0.937252223360968 | PAK3, GMFG, THBS1, CD74 | 82 | 973 | 13528 | 0.678214223046649 | 1 | 0.999999909351271 | 100
GOTERM_BP_FAT | GO:0006796~phosphate metabolic process | 4 | 4.08163265306122 | 0.937252223360968 | PAK3, GMFG, THBS1, CD74 | 82 | 973 | 13528 | 0.678214223046649 | 1 | 0.999999909351271 | 100
Annotation Cluster 63 | Enrichment Score: 6.705811072562509E-5
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | transcription regulation | 3 | 3.06122448979591 | 0.999751526506321 | BTG2, PPARG, ZEB2 | 98 | 2026 | 19235 | 0.290635010173862 | 1 | 0.999999999998523 | 100
SP_PIR_KEYWORDS | Transcription | 3 | 3.06122448979591 | 0.999802981363425 | BTG2, PPARG, ZEB2 | 98 | 2071 | 19235 | 0.284319908552508 | 1 | 0.999999999999017 | 100
GOTERM_BP_FAT | GO:0006350~transcription | 3 | 3.06122448979591 | 0.999982321553529 | BTG2, PPARG, ZEB2 | 82 | 2101 | 13528 | 0.235567267619368 | 1 | 1 | 100