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Sheet: Sheet1

Supp Table 5. The 33 model predicted carbon sources. The following are reported: predicted biomass yields (assuming no oxygen limitations); oxygen requirements (mmol O2 needed/mmol carbon source or mmol [NAME] needed/mmol electron equivalent); and comparison with experimental data. References to other papers correspond to PubMed IDs. All simulations used a maximum carbon uptake rate = 10 mmol/gAFDW/hr, and an unconstrained oxygen uptake rate. | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6
[NAME] | Abbreviation | BiomassYield (gAFDW/ mmol carbon source) | O2 Requirement (mmolO2/ mmol carbon source) | O2 Requirement (mmolO2/ mmol electron equiv.) | Comment | Source of Experimental Evidence
Acetate | ac | 0.0132 | 1.4034 | 0.2005 | Growth | PMID: 16788168, This study
N-Acetyl-D-glucosamine | acgam | 0.0643 | 5.0894 | 0.159 | Growth | PMID: 18546496
2-Oxoglutarate | akg | 0.0326 | 2.5244 | 0.1803 | Weak | This Study
D-Alanine | ala-D | 0.0235 | 1.9367 | 0.1614 | Untested
L-Alanine | ala-L | 0.0235 | 1.9367 | 0.1614 | Weak | This Study
L-Arginine | arg-L | 0.0413 | 3.6302 | 0.1578 | Untested
L-Aspartate | asp-L | 0.0234 | 1.943 | 0.1766 | No Growth | This Study
Cytidine | cytd | 0.0458 | 2.9522 | 0.0984 | Untested
Deoxycytidine | dcyt | 0.0497 | 3.2805 | 0.1025 | Untested
[NAME] | duri | 0.0491 | 3.3072 | 0.1034 | Untested
Ethanol | etoh | 0.0234 | 1.9396 | 0.1616 | [NAME] | PMID: 8195102, this study
Formate | for | 0.0035 | 0.3401 | 0.3401 | [NAME] | PMID: 8195102, this study
Fumarate | fum | 0.024 | 1.9162 | 0.1916 | Growth | This Study
L-Glutamine | gln-L | 0.0368 | 2.8339 | 0.1574 | Growth | This Study
L-Glutamate | [NAME] | 0.0366 | 2.8419 | 0.1672 | Growth | This Study
Glycine | gly | 0.0118 | 0.9649 | 0.1608 | No Growth | This Study
gly-asp-L | gly-asp-L | 0.0356 | 2.8902 | 0.17 | Growth | PMID: 16788168 (Biolog Data)
gly-glu-L | gly-glu-L | 0.0477 | 3.8409 | 0.167 | Growth | PMID: 16788168 (Biolog Data)
(R)-Glycerate | glyc-R | 0.0198 | 1.6047 | 0.1783 | Untested
Glycolate | glyclt | 0.0107 | 1.0163 | 0.2033 | Untested
hexadecanoate (n-C16:0) | hdca | 0.1601 | 15.7573 | 0.1694 | Untested
D-Lactate | lac-D | 0.0212 | 2.042 | 0.1856 | Growth | PMID: 19196979
L-Lactate | lac-L | 0.0212 | 2.042 | 0.1856 | Growth | PMID: 19196979,16788168, and this study
L-Malate | mal-L | 0.024 | 1.9162 | 0.1916 | Growth | This Study
octadecanoate (n-C18:0) | ocdca | 0.1812 | 17.7992 | 0.1695 | Untested
L-Ornithine | orn-L | 0.0355 | 3.8953 | 0.1694 | Untested
Propionate | ppa | 0.0228 | 2.4674 | 0.1898 | Growth | This Study
Putrescine | ptrc | 0.0348 | 3.9269 | 0.1636 | Untested
Pyruvate | pyr | 0.0195 | 1.6157 | 0.1795 | Growth | PMID: 16788168, and this study
L-Serine | ser-L | 0.0199 | 1.6009 | 0.1601 | Growth | PMID: 8195102, and this study
Succinate | succ | 0.0256 | 2.341 | 0.1951 | Growth | This Study
tetradecanoate (C14:0) | ttdca | 0.1386 | 13.7274 | 0.1695 | Untested
Uridine | [NAME] | 0.0452 | 2.9799 | 0.0993 | Growth | PMID: 16788168 (Biolog Data)
Other Compounds Not Predicted by Model to Support Growth
Asparagine | asn-L | 0 | 0 | 0 | Weak | This Study (No growth in plate, some growth after 4 days in culture tube)
Threonine | [NAME] | 0 | 0 | 0 | Growth | This Study (thr-L uptake transporter is needed in model to allow for growth)
Adenosine | adn | 0 | 0 | 0 | Growth | PMID: 16788168 (hxan transporter is needed in model to allow for growth)
[NAME] | dad-2 | 0 | 0 | 0 | Growth | PMID: 16788168 (hxan transporter is needed in model to allow for growth)
Inosine | ins | 0 | 0 | 0 | Growth | PMID: 18546496 (hxan transporter is needed in model to allow for growth)