Spreadsheet: 3da8e16b-bdd7-47cc-a6a6-914364e9a554
Sheet: Sheet1

Supplementary Table S4 | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8
Wilcoxon rank-sum test (buccal mucosa vs. supragingival plaque)
----------------------------------------------------------
JCVI Metagenomics Reports - Comparison Results - Wilcoxon Signed Rank Test
Version: | 1.2.4-beta
Date: |  | May 5, 2011, 10:25 am
Query: |  | *:* NOT blast_tree:7711
Datasets:
 |  | buccal-mucosa-mtr
 |  | supragingival-plaque-mtr
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Enriched in Buccal mucosa
ID | Category | %Median (buccal-mucosa-mtr) | %MAD (buccal-mucosa-mtr) | %Median (supragingival-plaque-mtr) | %MAD (supragingival-plaque-mtr) | [NAME] | P-Value | P-Value (Bonf. [NAME].)
5150 | Staphylococcus aureus infection | 0.2851 | 0.0873 | 0.0676 | 0.0325 | 4.217 | 0 | 0
4210 | Apoptosis | 0.0311 | 0.0082 | 0.0092 | 0.0033 | 3.38 | 0 | 0
4622 | RIG-I-like receptor signaling pathway | 0.0192 | 0.0116 | 0.0074 | 0.0028 | 2.595 | 0 | 0
565 | Ether lipid metabolism | 0.0267 | 0.0072 | 0.0115 | 0.0055 | 2.322 | 0 | 0
622 | Xylene degradation | 0.0631 | 0.0142 | 0.0287 | 0.0083 | 2.199 | 0 | 0
621 | Dioxin degradation | 0.1109 | 0.0279 | 0.0511 | 0.0138 | 2.17 | 0 | 0
311 | Penicillin and cephalosporin biosynthesis | 0.063 | 0.0186 | 0.033 | 0.0096 | 1.909 | 0 | 0
4973 | Carbohydrate digestion and absorption | 0.0751 | 0.022 | 0.0394 | 0.0077 | 1.906 | 0 | 0
511 | Other glycan degradation | 0.3138 | 0.0703 | 0.166 | 0.0396 | 1.89 | 0 | 0
830 | Retinol metabolism | 0.1248 | 0.0279 | 0.0676 | 0.0211 | 1.846 | 0 | 0
531 | Glycosaminoglycan degradation | 0.0807 | 0.0242 | 0.0439 | 0.0151 | 1.838 | 0 | 0
604 | Glycosphingolipid biosynthesis - ganglio series | 0.0728 | 0.0221 | 0.0402 | 0.0144 | 1.811 | 0 | 0
72 | Synthesis and degradation of ketone bodies | 0.0756 | 0.0184 | 0.0418 | 0.0101 | 1.809 | 0 | 0
980 | Metabolism of xenobiotics by cytochrome P450 | 0.1317 | 0.0283 | 0.073 | 0.0258 | 1.804 | 0 | 0
982 | Drug metabolism - cytochrome P450 | 0.1319 | 0.0281 | 0.0737 | 0.0259 | 1.79 | 0 | 0
312 | beta-Lactam resistance | 0.0274 | 0.0062 | 0.0156 | 0.0046 | 1.756 | 0 | 0
625 | Chloroalkane and chloroalkene degradation | 0.2593 | 0.0434 | 0.1664 | 0.0246 | 1.558 | 0 | 0
2060 | Phosphotransferase system (PTS) | 1.2736 | 0.2094 | 0.823 | 0.1391 | 1.548 | 0 | 0
626 | Naphthalene degradation | 0.3221 | 0.063 | 0.2215 | 0.0262 | 1.454 | 0 | 0
253 | Tetracycline biosynthesis | 0.2699 | 0.0334 | 0.1888 | 0.0351 | 1.43 | 0 | 0
603 | Glycosphingolipid biosynthesis - globo series | 0.0926 | 0.0243 | 0.0652 | 0.0151 | 1.42 | 0 | 0
3013 | RNA transport | 0.1548 | 0.0162 | 0.1099 | 0.0123 | 1.409 | 0 | 0
4142 | Lysosome | 0.1134 | 0.0248 | 0.0818 | 0.0219 | 1.386 | 0 | 0
52 | Galactose metabolism | 1.1625 | 0.1345 | 0.8609 | 0.0833 | 1.35 | 0 | 0
730 | Thiamine metabolism | 0.7028 | 0.0618 | 0.5212 | 0.0356 | 1.348 | 0 | 0
627 | Aminobenzoate degradation | 0.3277 | 0.0541 | 0.245 | 0.0268 | 1.338 | 0 | 0
473 | D-Alanine metabolism | 0.2845 | 0.0371 | 0.2173 | 0.0154 | 1.309 | 0 | 0
930 | Caprolactam degradation | 0.0531 | 0.0119 | 0.0406 | 0.0089 | 1.308 | 0 | 0
561 | Glycerolipid metabolism | 0.605 | 0.0628 | 0.4743 | 0.0442 | 1.276 | 0 | 0
642 | Ethylbenzene degradation | 0.1124 | 0.0295 | 0.0903 | 0.0228 | 1.245 | 0 | 0
624 | Polycyclic aromatic hydrocarbon degradation | 0.2982 | 0.0543 | 0.2417 | 0.0252 | 1.234 | 0 | 0
4070 | Phosphatidylinositol signaling system | 0.2195 | 0.018 | 0.1784 | 0.0212 | 1.23 | 0 | 0
524 | [NAME] and neomycin biosynthesis | 0.0647 | 0.0114 | 0.0532 | 0.008 | 1.216 | 0 | 0
362 | Benzoate degradation | 0.3245 | 0.0654 | 0.2701 | 0.0357 | 1.201 | 0 | 0
440 | Phosphonate and phosphinate metabolism | 0.0999 | 0.0103 | 0.0838 | 0.0116 | 1.192 | 0 | 0
550 | Peptidoglycan biosynthesis | 1.4865 | 0.0743 | 1.2783 | 0.0356 | 1.163 | 0 | 0
520 | Amino sugar and nucleotide sugar metabolism | 2.5422 | 0.1689 | 2.1875 | 0.1256 | 1.162 | 0 | 0
790 | Folate biosynthesis | 0.646 | 0.0281 | 0.5593 | 0.0243 | 1.155 | 0 | 0
51 | Fructose and mannose metabolism | 1.4854 | 0.0971 | 1.2969 | 0.1065 | 1.145 | 0 | 0
2010 | ABC transporters | 6.1481 | 0.3944 | 5.424 | 0.4193 | 1.133 | 0 | 0
350 | Tyrosine metabolism | 0.6954 | 0.0787 | 0.616 | 0.035 | 1.129 | 0 | 0
2020 | Two-component system | 1.9427 | 0.1589 | 1.7259 | 0.1352 | 1.126 | 0 | 0
460 | Cyanoamino acid metabolism | 0.3079 | 0.0186 | 0.2792 | 0.0268 | 1.103 | 0 | 0
591 | Linoleic acid metabolism | 0.0615 | 0.0076 | 0.0558 | 0.005 | 1.102 | 1e-06 | 0.000299
71 | Fatty acid metabolism | 0.3418 | 0.0279 | 0.3151 | 0.0236 | 1.085 | 0 | 0
3430 | Mismatch repair | 1.3762 | 0.0316 | 1.2946 | 0.0517 | 1.063 | 0 | 0
3440 | Homologous recombination | 1.7266 | 0.0483 | 1.6338 | 0.0544 | 1.057 | 0 | 0
400 | Phenylalanine, tyrosine and tryptophan biosynthesis | 1.3562 | 0.0746 | 1.2909 | 0.0669 | 1.051 | 0 | 0
564 | Glycerophospholipid metabolism | 0.9853 | 0.0655 | 0.9381 | 0.0584 | 1.05 | 4e-06 | 0.001196
3030 | DNA replication | 1.2117 | 0.0408 | 1.1726 | 0.038 | 1.033 | 0 | 0
300 | Lysine biosynthesis | 1.0306 | 0.0456 | 1.0024 | 0.0409 | 1.028 | 3.4e-05 | 0.010166
270 | Cysteine and methionine metabolism | 1.5454 | 0.0457 | 1.5129 | 0.0495 | 1.021 | 1.4e-05 | 0.004186
Enriched in Supragingival plaque
ID | Category | %Median (buccal-mucosa-mtr) | %MAD (buccal-mucosa-mtr) | %Median (supragingival-plaque-mtr) | %MAD (supragingival-plaque-mtr) | [NAME] | P-Value | P-Value (Bonf. [NAME].)
5140 | Leishmaniasis | 0.0002 | 0.0001 | 0.0017 | 0.0007 | 0.118 | 0 | 0
5322 | Systemic lupus erythematosus | 0.0024 | 0.0027 | 0.0203 | 0.0107 | 0.118 | 0 | 0
4514 | Cell adhesion molecules (CAMs) | 0.0001 | 0.0001 | 0.0008 | 0.0004 | 0.125 | 0 | 0
5131 | Shigellosis | 0.0013 | 0.0013 | 0.0096 | 0.0059 | 0.135 | 0 | 0
5100 | Bacterial invasion of epithelial cells | 0.0013 | 0.0012 | 0.0084 | 0.0047 | 0.155 | 0 | 0
4380 | Osteoclast differentiation | 0.0003 | 0.0001 | 0.0019 | 0.0009 | 0.158 | 0 | 0
4062 | Chemokine signaling pathway | 0.0015 | 0.0013 | 0.0093 | 0.0056 | 0.161 | 0 | 0
4520 | Adherens junction | 0.0016 | 0.0015 | 0.0098 | 0.0058 | 0.163 | 0 | 0
62 | Fatty acid elongation in mitochondria | 0.0001 | 0.0001 | 0.0006 | 0.0003 | 0.167 | 0 | 0
5217 | Basal cell carcinoma | 0.0002 | 0.0001 | 0.0012 | 0.0004 | 0.167 | 0 | 0
4620 | Toll-like receptor signaling pathway | 0.0003 | 0.0001 | 0.0018 | 0.0007 | 0.167 | 0 | 0
351 | 1,1,1-Trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) degradation | 0.0003 | 0.0003 | 0.0018 | 0.0013 | 0.167 | 0 | 0
140 | Steroid hormone biosynthesis | 0.0014 | 0.0009 | 0.0083 | 0.0047 | 0.169 | 0 | 0
5219 | Bladder cancer | 0.0016 | 0.0013 | 0.009 | 0.0049 | 0.178 | 0 | 0
4130 | SNARE interactions in vesicular transport | 0.0002 | 0.0001 | 0.0011 | 0.0007 | 0.182 | 0 | 0
3050 | Proteasome | 0.0044 | 0.0039 | 0.0238 | 0.012 | 0.185 | 0 | 0
5143 | African trypanosomiasis | 0.0066 | 0.0056 | 0.0356 | 0.0113 | 0.185 | 0 | 0
4660 | T cell receptor signaling pathway | 0.0006 | 0.0004 | 0.0032 | 0.0012 | 0.188 | 0 | 0
5142 | Chagas disease (American trypanosomiasis) | 0.0068 | 0.0057 | 0.0362 | 0.0123 | 0.188 | 0 | 0
4664 | Fc epsilon RI signaling pathway | 0.0002 | 0.0001 | 0.001 | 0.0004 | 0.2 | 0 | 0
4150 | mTOR signaling pathway | 0.0004 | 0.0003 | 0.0019 | 0.0009 | 0.211 | 0 | 0
4140 | Regulation of autophagy | 0.0003 | 0.0002 | 0.0014 | 0.0007 | 0.214 | 0 | 0
4320 | Dorso-ventral axis formation | 0.0009 | 0.0006 | 0.0042 | 0.0018 | 0.214 | 0 | 0
563 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis | 0.0005 | 0.0004 | 0.0023 | 0.0009 | 0.217 | 0 | 0
4964 | Proximal tubule bicarbonate reclamation | 0.0168 | 0.0144 | 0.0774 | 0.0265 | 0.217 | 0 | 0
906 | Carotenoid biosynthesis | 0.0024 | 0.0024 | 0.011 | 0.004 | 0.218 | 0 | 0
4623 | Cytosolic DNA-sensing pathway | 0.0002 | 0.0001 | 0.0009 | 0.0004 | 0.222 | 0 | 0
4740 | Olfactory transduction | 0.0002 | 0.0001 | 0.0009 | 0.0004 | 0.222 | 0 | 0
5130 | Pathogenic Escherichia coli infection | 0.002 | 0.0018 | 0.009 | 0.0047 | 0.222 | 0 | 0
4962 | Vasopressin-regulated water reabsorption | 0.0005 | 0.0004 | 0.0022 | 0.001 | 0.227 | 0 | 0
4662 | B cell receptor signaling pathway | 0.0003 | 0.0002 | 0.0013 | 0.0004 | 0.231 | 0 | 0
4630 | Jak-STAT signaling pathway | 0.0007 | 0.0006 | 0.003 | 0.0016 | 0.233 | 0 | 0
100 | Steroid biosynthesis | 0.0004 | 0.0003 | 0.0017 | 0.0007 | 0.235 | 0 | 0
5220 | Chronic myeloid leukemia | 0.0004 | 0.0003 | 0.0017 | 0.0009 | 0.235 | 0 | 0
4540 | Gap junction | 0.0004 | 0.0003 | 0.0017 | 0.0009 | 0.235 | 0 | 0
4970 | [NAME] secretion | 0.0005 | 0.0004 | 0.0021 | 0.0009 | 0.238 | 0 | 0
4711 | Circadian rhythm - fly | 0.0001 | 0.0001 | 0.0004 | 0.0001 | 0.25 | 0 | 0
4710 | Circadian rhythm - mammal | 0.0001 | 0.0001 | 0.0004 | 0.0001 | 0.25 | 0 | 0
4060 | Cytokine-cytokine receptor interaction | 0.0001 | 0.0001 | 0.0004 | 0.0001 | 0.25 | 0 | 0
4950 | Maturity onset diabetes of the young | 0.0001 | 0.0001 | 0.0004 | 0.0001 | 0.25 | 0 | 0
5218 | Melanoma | 0.0001 | 0.0001 | 0.0004 | 0.0001 | 0.25 | 0 | 0
4742 | Taste transduction | 0.0001 | 0.0001 | 0.0004 | 0.0003 | 0.25 | 0 | 0
4960 | Aldosterone-regulated sodium reabsorption | 0.0002 | 0.0001 | 0.0008 | 0.0003 | 0.25 | 0 | 0
4670 | [NAME] transendothelial migration | 0.0002 | 0.0001 | 0.0008 | 0.0003 | 0.25 | 0 | 0
5223 | Non-small cell lung cancer | 0.0002 | 0.0001 | 0.0008 | 0.0004 | 0.25 | 0 | 0
364 | Fluorobenzoate degradation | 0.0003 | 0.0003 | 0.0012 | 0.0006 | 0.25 | 0 | 0
4971 | Gastric acid secretion | 0.0003 | 0.0003 | 0.0012 | 0.0006 | 0.25 | 0 | 0
4640 | Hematopoietic cell lineage | 0.0003 | 0.0003 | 0.0012 | 0.0006 | 0.25 | 0 | 0
4966 | Collecting duct acid secretion | 0.0003 | 0.0003 | 0.0012 | 0.0007 | 0.25 | 0 | 0
4340 | Hedgehog signaling pathway | 0.0004 | 0.0003 | 0.0016 | 0.0004 | 0.25 | 0 | 0
4722 | Neurotrophin signaling pathway | 0.0005 | 0.0004 | 0.002 | 0.0009 | 0.25 | 0 | 0
4115 | p53 signaling pathway | 0.0008 | 0.0006 | 0.0032 | 0.0019 | 0.25 | 0 | 0
4310 | Wnt signaling pathway | 0.0018 | 0.0013 | 0.0072 | 0.0031 | 0.25 | 0 | 0
4010 | MAPK signaling pathway | 0.0019 | 0.0012 | 0.0076 | 0.0025 | 0.25 | 0 | 0
592 | alpha-Linolenic acid metabolism | 0.004 | 0.003 | 0.016 | 0.0083 | 0.25 | 0 | 0
941 | Flavonoid biosynthesis | 0.0043 | 0.0021 | 0.0165 | 0.0044 | 0.261 | 0 | 0
4260 | Cardiac muscle contraction | 0.009 | 0.0084 | 0.034 | 0.0169 | 0.265 | 0 | 0
5160 | Hepatitis C | 0.0004 | 0.0003 | 0.0015 | 0.0006 | 0.267 | 0 | 0
4370 | VEGF signaling pathway | 0.0004 | 0.0003 | 0.0015 | 0.0006 | 0.267 | 0 | 0
3040 | Spliceosome | 0.0194 | 0.0089 | 0.0723 | 0.0383 | 0.268 | 0 | 0
4810 | Regulation of actin cytoskeleton | 0.0028 | 0.0014 | 0.0103 | 0.0055 | 0.272 | 0 | 0
4730 | Long-term depression | 0.0003 | 0.0003 | 0.0011 | 0.0006 | 0.273 | 0 | 0
4360 | Axon guidance | 0.0006 | 0.0004 | 0.0022 | 0.0009 | 0.273 | 0 | 0
4912 | GnRH signaling pathway | 0.0006 | 0.0004 | 0.0022 | 0.0009 | 0.273 | 0 | 0
4330 | Notch signaling pathway | 0.0006 | 0.0004 | 0.0022 | 0.001 | 0.273 | 0 | 0
3015 | mRNA surveillance pathway | 0.0025 | 0.001 | 0.0091 | 0.0055 | 0.275 | 0 | 0
4916 | Melanogenesis | 0.0005 | 0.0003 | 0.0018 | 0.0007 | 0.278 | 0 | 0
4650 | Natural killer cell mediated cytotoxicity | 0.0005 | 0.0004 | 0.0018 | 0.0007 | 0.278 | 0 | 0
4666 | Fc gamma R-mediated phagocytosis | 0.0029 | 0.0014 | 0.0104 | 0.0055 | 0.279 | 0 | 0
510 | N-Glycan biosynthesis | 0.0179 | 0.0095 | 0.0637 | 0.0145 | 0.281 | 0 | 0
5214 | Glioma | 0.0002 | 0.0001 | 0.0007 | 0.0003 | 0.286 | 0 | 0
4350 | TGF-beta signaling pathway | 0.0009 | 0.0006 | 0.0031 | 0.0012 | 0.29 | 0 | 0
513 | Various types of N-glycan biosynthesis | 0.0009 | 0.0006 | 0.0031 | 0.0016 | 0.29 | 0 | 0
4974 | Protein digestion and absorption | 0.0079 | 0.0056 | 0.0269 | 0.015 | 0.294 | 0 | 0
2040 | [NAME] assembly | 0.0381 | 0.0232 | 0.1297 | 0.0884 | 0.294 | 0 | 0
4020 | Calcium signaling pathway | 0.0008 | 0.0004 | 0.0027 | 0.001 | 0.296 | 0 | 0
4530 | Tight junction | 0.0008 | 0.0006 | 0.0027 | 0.0012 | 0.296 | 0 | 0
5145 | Toxoplasmosis | 0.0016 | 0.0009 | 0.0054 | 0.0021 | 0.296 | 0 | 0
5144 | Malaria | 0.0003 | 0.0003 | 0.001 | 0.0004 | 0.3 | 0 | 0
4012 | ErbB signaling pathway | 0.0006 | 0.0004 | 0.002 | 0.001 | 0.3 | 0 | 0
4976 | Bile secretion | 0.0014 | 0.0006 | 0.0046 | 0.0013 | 0.304 | 0 | 0
5012 | Parkinson's disease | 0.0143 | 0.0113 | 0.0471 | 0.0172 | 0.304 | 0 | 0
4144 | Endocytosis | 0.0038 | 0.0019 | 0.0124 | 0.0047 | 0.306 | 0 | 0
4013 | MAPK signaling pathway - fly | 0.0005 | 0.0004 | 0.0016 | 0.0006 | 0.313 | 0 | 0
4745 | Phototransduction - fly | 0.0001 | 0.0001 | 0.0003 | 0.0001 | 0.333 | 0 | 0
5216 | Thyroid cancer | 0.0001 | 0.0001 | 0.0003 | 0.0001 | 0.333 | 0 | 0
5221 | Acute myeloid leukemia | 0.0002 | 0.0001 | 0.0006 | 0.0003 | 0.333 | 0 | 0
5213 | Endometrial cancer | 0.0004 | 0.0003 | 0.0012 | 0.0004 | 0.333 | 0 | 0
4270 | Vascular smooth muscle contraction | 0.0004 | 0.0003 | 0.0012 | 0.0007 | 0.333 | 0 | 0
4720 | Long-term potentiation | 0.0005 | 0.0004 | 0.0015 | 0.0007 | 0.333 | 0 | 0
4972 | Pancreatic secretion | 0.0006 | 0.0003 | 0.0017 | 0.0006 | 0.353 | 0 | 0
3022 | Basal transcription factors | 0.0011 | 0.0007 | 0.0031 | 0.001 | 0.355 | 0 | 0
4080 | Neuroactive ligand-receptor interaction | 0.0004 | 0.0003 | 0.0011 | 0.0004 | 0.364 | 0 | 0
4113 | Meiosis - yeast | 0.0132 | 0.0073 | 0.0363 | 0.0089 | 0.364 | 0 | 0
361 | Chlorocyclohexane and chlorobenzene degradation | 0.0036 | 0.002 | 0.0098 | 0.0034 | 0.367 | 0 | 0
4920 | Adipocytokine signaling pathway | 0.0602 | 0.0272 | 0.1609 | 0.0248 | 0.374 | 0 | 0
514 | Other types of O-glycan biosynthesis | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.375 | 0 | 0
5146 | Amoebiasis | 0.0038 | 0.0022 | 0.0101 | 0.0036 | 0.376 | 0 | 0
643 | Styrene degradation | 0.0086 | 0.0059 | 0.0229 | 0.0099 | 0.376 | 0 | 0
4145 | Phagosome | 0.0017 | 0.001 | 0.0045 | 0.0018 | 0.378 | 0 | 0
5210 | Colorectal cancer | 0.0009 | 0.0006 | 0.0023 | 0.0009 | 0.391 | 0 | 0
4614 | Renin-angiotensin system | 0.0006 | 0.0003 | 0.0015 | 0.0006 | 0.4 | 0 | 0
4712 | Circadian rhythm - plant | 0.0006 | 0.0004 | 0.0015 | 0.0006 | 0.4 | 0 | 0
5200 | Pathways in cancer | 0.0479 | 0.0225 | 0.1163 | 0.0157 | 0.412 | 0 | 0
4120 | Ubiquitin mediated proteolysis | 0.0028 | 0.0019 | 0.0067 | 0.0022 | 0.418 | 0 | 0
5211 | Renal cell carcinoma | 0.034 | 0.0158 | 0.0814 | 0.0101 | 0.418 | 0 | 0
5215 | Prostate cancer | 0.0117 | 0.0084 | 0.0274 | 0.0141 | 0.427 | 0 | 0
5410 | Hypertrophic cardiomyopathy (HCM) | 0.0003 | 0.0003 | 0.0007 | 0.0003 | 0.429 | 0 | 0
5414 | Dilated cardiomyopathy (DCM) | 0.0003 | 0.0003 | 0.0007 | 0.0004 | 0.429 | 0 | 0
4612 | Antigen processing and presentation | 0.0123 | 0.0081 | 0.0286 | 0.013 | 0.43 | 0 | 0
472 | D-Arginine and D-ornithine metabolism | 0.003 | 0.0025 | 0.0068 | 0.0037 | 0.441 | 0 | 0
4914 | Progesterone-mediated oocyte maturation | 0.0132 | 0.0087 | 0.0292 | 0.0132 | 0.452 | 0 | 0
360 | Phenylalanine metabolism | 0.1008 | 0.0405 | 0.209 | 0.0242 | 0.482 | 0 | 0
860 | Porphyrin and chlorophyll metabolism | 0.6345 | 0.2463 | 1.2885 | 0.1751 | 0.492 | 0 | 0
623 | Toluene degradation | 0.1505 | 0.0589 | 0.3026 | 0.034 | 0.497 | 0 | 0
534 | Glycosaminoglycan biosynthesis - heparan sulfate | 0.0001 | 0.0001 | 0.0002 | 0.0001 | 0.5 | 0 | 0
601 | Glycosphingolipid biosynthesis - lacto and neolacto series | 0.0001 | 0.0001 | 0.0002 | 0.0001 | 0.5 | 0 | 0
5212 | Pancreatic cancer | 0.0002 | 0.0001 | 0.0004 | 0.0001 | 0.5 | 0 | 0
120 | Primary bile acid biosynthesis | 0.0002 | 0.0001 | 0.0004 | 0.0003 | 0.5 | 0 | 0
4141 | Protein processing in endoplasmic reticulum | 0.0246 | 0.011 | 0.0479 | 0.0176 | 0.514 | 0 | 0
950 | Isoquinoline alkaloid biosynthesis | 0.0342 | 0.0168 | 0.0664 | 0.0203 | 0.515 | 0 | 0
4114 | Oocyte meiosis | 0.002 | 0.0012 | 0.0038 | 0.0013 | 0.526 | 0 | 0
20 | Citrate cycle (TCA cycle) | 0.7444 | 0.201 | 1.414 | 0.1256 | 0.526 | 0 | 0
960 | Tropane, piperidine and pyridine alkaloid biosynthesis | 0.0849 | 0.0314 | 0.1576 | 0.017 | 0.539 | 0 | 0
945 | Stilbenoid, diarylheptanoid and gingerol biosynthesis | 0.0075 | 0.0028 | 0.013 | 0.0033 | 0.577 | 0 | 0
130 | Ubiquinone and other terpenoid-quinone biosynthesis | 0.2126 | 0.0818 | 0.3655 | 0.0414 | 0.582 | 0 | 0
340 | Histidine metabolism | 0.51 | 0.0881 | 0.8666 | 0.0795 | 0.589 | 0 | 0
5222 | Small cell lung cancer | 0.0008 | 0.0005 | 0.0013 | 0.0006 | 0.615 | 0 | 0
190 | Oxidative phosphorylation | 1.253 | 0.2454 | 2.0297 | 0.1816 | 0.617 | 0 | 0
630 | Glyoxylate and dicarboxylate metabolism | 0.3928 | 0.0825 | 0.6349 | 0.0546 | 0.619 | 0 | 0
944 | Flavone and flavonol biosynthesis | 0.0005 | 0.0004 | 0.0008 | 0.0004 | 0.625 | 4e-06 | 0.001196
3320 | PPAR signaling pathway | 0.1486 | 0.0221 | 0.2371 | 0.0479 | 0.627 | 0 | 0
410 | beta-Alanine metabolism | 0.1621 | 0.0369 | 0.2573 | 0.0237 | 0.63 | 0 | 0
523 | Polyketide sugar unit biosynthesis | 0.2295 | 0.0686 | 0.3568 | 0.0426 | 0.643 | 0 | 0
5010 | Alzheimer's disease | 0.1275 | 0.0219 | 0.198 | 0.0258 | 0.644 | 0 | 0
4510 | Focal adhesion | 0.0026 | 0.0015 | 0.004 | 0.0013 | 0.65 | 0 | 0
3008 | Ribosome biogenesis in eukaryotes | 0.0972 | 0.016 | 0.1459 | 0.0206 | 0.666 | 0 | 0
280 | [NAME], leucine and isoleucine degradation | 0.364 | 0.0511 | 0.5367 | 0.0648 | 0.678 | 0 | 0
1055 | Biosynthesis of vancomycin group antibiotics | 0.0873 | 0.013 | 0.1276 | 0.0132 | 0.684 | 0 | 0
5016 | Huntington's disease | 0.1189 | 0.0179 | 0.1718 | 0.0256 | 0.692 | 0 | 0
521 | Streptomycin biosynthesis | 0.3746 | 0.0772 | 0.5414 | 0.05 | 0.692 | 0 | 0
401 | Novobiocin biosynthesis | 0.1307 | 0.026 | 0.1878 | 0.0156 | 0.696 | 0 | 0
2030 | Bacterial chemotaxis | 0.1562 | 0.0196 | 0.2234 | 0.0645 | 0.699 | 0 | 0
310 | Lysine degradation | 0.1992 | 0.0254 | 0.285 | 0.024 | 0.699 | 0 | 0
720 | Carbon fixation in prokaryotes | 1.0463 | 0.1523 | 1.4848 | 0.1085 | 0.705 | 0 | 0
4146 | Peroxisome | 0.2705 | 0.0447 | 0.3832 | 0.0335 | 0.706 | 0 | 0
562 | Inositol phosphate metabolism | 0.1768 | 0.0169 | 0.2492 | 0.0507 | 0.709 | 0 | 0
4940 | Type I diabetes mellitus | 0.0987 | 0.0079 | 0.1357 | 0.0144 | 0.727 | 0 | 0
4910 | Insulin signaling pathway | 0.1406 | 0.0122 | 0.1927 | 0.0148 | 0.73 | 0 | 0
540 | Lipopolysaccharide biosynthesis | 0.4451 | 0.202 | 0.6076 | 0.2133 | 0.733 | 1e-06 | 0.000299
330 | Arginine and proline metabolism | 1.053 | 0.1197 | 1.4311 | 0.0936 | 0.736 | 0 | 0
5014 | Amyotrophic lateral sclerosis (ALS) | 0.0387 | 0.0186 | 0.0521 | 0.0132 | 0.743 | 0 | 0
5416 | Viral myocarditis | 0.0015 | 0.0006 | 0.002 | 0.0006 | 0.75 | 0 | 0
910 | Nitrogen metabolism | 1.0299 | 0.1509 | 1.3251 | 0.0554 | 0.777 | 0 | 0
785 | Lipoic acid metabolism | 0.1081 | 0.0164 | 0.1383 | 0.0169 | 0.782 | 0 | 0
3018 | RNA degradation | 0.8062 | 0.0665 | 1.0215 | 0.0546 | 0.789 | 0 | 0
633 | [NAME] degradation | 0.0491 | 0.0218 | 0.0619 | 0.0193 | 0.793 | 0.000132 | 0.039468
780 | Biotin metabolism | 0.167 | 0.0412 | 0.2102 | 0.0396 | 0.794 | 0 | 0
3020 | RNA polymerase | 0.6072 | 0.0483 | 0.764 | 0.0571 | 0.795 | 0 | 0
1040 | Biosynthesis of unsaturated fatty acids | 0.1712 | 0.0139 | 0.2117 | 0.0154 | 0.809 | 0 | 0
250 | Alanine, aspartate and glutamate metabolism | 1.273 | 0.0873 | 1.5722 | 0.0924 | 0.81 | 0 | 0
380 | Tryptophan metabolism | 0.245 | 0.0213 | 0.2946 | 0.0212 | 0.832 | 0 | 0
3420 | Nucleotide excision repair | 0.6317 | 0.0277 | 0.7588 | 0.0451 | 0.832 | 0 | 0
710 | Carbon fixation in photosynthetic organisms | 0.9061 | 0.0629 | 1.0801 | 0.109 | 0.839 | 0 | 0
5340 | Primary immunodeficiency | 0.0826 | 0.0087 | 0.0982 | 0.0101 | 0.841 | 0 | 0
40 | Pentose and glucuronate interconversions | 0.3027 | 0.0509 | 0.357 | 0.0455 | 0.848 | 0 | 0
740 | [NAME] metabolism | 0.2682 | 0.052 | 0.3155 | 0.0387 | 0.85 | 0 | 0
3010 | Ribosome | 5.418 | 0.2685 | 6.3191 | 0.3557 | 0.857 | 0 | 0
3070 | Bacterial secretion system | 1.0587 | 0.0652 | 1.2326 | 0.0566 | 0.859 | 0 | 0
4930 | Type II diabetes mellitus | 0.0828 | 0.0073 | 0.0962 | 0.0053 | 0.861 | 0 | 0
4626 | Plant-pathogen interaction | 0.2254 | 0.0172 | 0.2613 | 0.02 | 0.863 | 0 | 0
640 | Propanoate metabolism | 0.7785 | 0.0466 | 0.9017 | 0.0418 | 0.863 | 0 | 0
4011 | MAPK signaling pathway - yeast | 0.0784 | 0.0069 | 0.0903 | 0.0073 | 0.868 | 0 | 0
260 | Glycine, serine and threonine metabolism | 1.2672 | 0.0455 | 1.4555 | 0.0676 | 0.871 | 0 | 0
920 | Sulfur metabolism | 0.4654 | 0.0331 | 0.5324 | 0.0423 | 0.874 | 0 | 0
680 | Methane metabolism | 1.4074 | 0.1365 | 1.6082 | 0.0762 | 0.875 | 0 | 0
760 | Nicotinate and nicotinamide metabolism | 0.5529 | 0.0369 | 0.6268 | 0.0279 | 0.882 | 0 | 0
650 | Butanoate metabolism | 0.9317 | 0.0526 | 1.0394 | 0.0901 | 0.896 | 0 | 0
5111 | Vibrio cholerae pathogenic cycle | 0.1264 | 0.0173 | 0.1395 | 0.0151 | 0.906 | 1.6e-05 | 0.004784
620 | Pyruvate metabolism | 1.672 | 0.0695 | 1.8385 | 0.0758 | 0.909 | 0 | 0
750 | [NAME] metabolism | 0.3067 | 0.0116 | 0.3363 | 0.0215 | 0.912 | 0 | 0
471 | D-Glutamine and D-glutamate metabolism | 0.2499 | 0.0168 | 0.2735 | 0.0193 | 0.914 | 0 | 0
3060 | Protein export | 1.1293 | 0.0417 | 1.2185 | 0.0534 | 0.927 | 0 | 0
10 | Glycolysis / Gluconeogenesis | 1.9683 | 0.1076 | 2.1224 | 0.1398 | 0.927 | 0 | 0
195 | Photosynthesis | 0.635 | 0.0308 | 0.6831 | 0.0366 | 0.93 | 0 | 0
660 | C5-Branched dibasic acid metabolism | 0.4383 | 0.0374 | 0.4705 | 0.0517 | 0.932 | 6e-06 | 0.001794
30 | Pentose phosphate pathway | 1.2092 | 0.0452 | 1.2844 | 0.0549 | 0.941 | 0 | 0
983 | Drug metabolism - other enzymes | 0.5273 | 0.0262 | 0.5549 | 0.0305 | 0.95 | 0 | 0
770 | Pantothenate and CoA biosynthesis | 0.8842 | 0.0318 | 0.9295 | 0.0541 | 0.951 | 0 | 0
430 | Taurine and hypotaurine metabolism | 0.2053 | 0.0236 | 0.2156 | 0.0116 | 0.952 | 5.3e-05 | 0.015847
970 | Aminoacyl-tRNA biosynthesis | 2.2234 | 0.1108 | 2.3362 | 0.1217 | 0.952 | 0 | 0
4112 | Cell cycle - Caulobacter | 0.8473 | 0.0225 | 0.8771 | 0.0417 | 0.966 | 1e-06 | 0.000299
670 | One carbon pool by folate | 0.8968 | 0.0324 | 0.9165 | 0.0319 | 0.979 | 3.1e-05 | 0.009269