Spreadsheet: 162fa7e9-3a84-45a1-9d57-6a220323e830
Sheet: Sheet1

SUPPLEMENTARY TABLE 2 | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14 | Unnamed: 15 | Unnamed: 16 | Unnamed: 17 | Unnamed: 18 | Unnamed: 19 | Unnamed: 20 | Unnamed: 21 | Unnamed: 22
Highlight colour indicates gene ontologies with >10 genes in common. Highlight colour is constant between groups.
Control |  |  |  |  |  |  |  | [NAME] |  |  |  |  |  |  |  | [NAME]
GO ID | GO Description | No. of genes | Total | Expected | Odds ratio | p-value |  | GO ID | GO Description | No. of genes | Total | Expected | Odds ratio | p-value |  | GO ID | GO Description | No. of genes | Total | Expected | Odds ratio | p-value
GO:0007275 | Multicellular organismal development | 366 | 1477 | 270.2922810060711 | 1.470738543048618 | 7.2e-14 |  | GO:0007275 | Multicellular organismal development | 441 | 1476 | 333.6041630529054 | 1.459094397544129 | 4.07e-15 |  | GO:0003700 | Transcription factor activity | 291 | 647 | 204.256721595837 | 1.771815964933942 | 8.07e-16
GO:0003700 | Transcription factor activity | 184 | 645 | 118.0355594102342 | 1.781908276875944 | 2.59e-12 |  | GO:0003700 | Transcription factor activity | 223 | 646 | 146.0083261058109 | 1.80530109639693 | 2.04e-14 |  | GO:0043565 | Sequence-specific DNA binding | 177 | 358 | 113.0199479618387 | 2.119680043713193 | 3.69e-14
GO:0032501 | Multicellular organismal process | 409 | 1730 | 316.5915004336513 | 1.382257445350535 | 3.25e-12 |  | GO:0032501 | Multicellular organismal process | 496 | 1729 | 390.7869904596704 | 1.377538514588892 | 1.08e-13 |  | GO:0007275 | Multicellular organismal development | 571 | 1478 | 466.601908065915 | 1.364597089790033 | 2.55e-13
GO:0048731 | System development | 283 | 1137 | 208.071986123157 | 1.479438827041966 | 1.44e-10 |  | GO:0048731 | System development | 341 | 1136 | 256.7576756287945 | 1.468832930296317 | 1.51e-11 |  | GO:0032501 | Multicellular organismal process | 647 | 1731 | 546.4735472679965 | 1.293750760309801 | 4.53e-12
[NAME] | Anatomical structure development | 319 | 1318 | 241.1951431049436 | 1.425586724164923 | 1.66e-10 |  | [NAME] | Anatomical structure development | 385 | 1317 | 297.6671292281006 | 1.414587992714074 | 1.9e-11 |  | GO:0048731 | System development | 447 | 1138 | 359.2645273200347 | 1.402184284601072 | 1.82e-11
GO:0048513 | Organ development | 230 | 892 | 163.2367736339983 | 1.551094629229249 | 3.68e-10 |  | GO:0009887 | Organ morphogenesis | 141 | 385 | 87.01734605377277 | 1.97885711409987 | 4.03e-11 |  | [NAME] | Anatomical structure development | 501 | 1319 | 416.4058976582828 | 1.327577984362825 | 3.56e-10
GO:0043565 | Sequence-specific DNA binding | 111 | 358 | 65.51431049436253 | 2.006293531861005 | 9.52e-10 |  | [NAME] | Anatomical structure morphogenesis | 254 | 807 | 182.3973980919341 | 1.572873283103813 | 6.46e-11 |  | GO:0048513 | Organ development | 354 | 892 | 281.6027753686037 | 1.426253114914825 | 1.99e-09
[NAME] | Anatomical structure morphogenesis | 208 | 807 | 147.6816999132697 | 1.55026149427561 | 5.04e-09 |  | GO:0032502 | Developmental process | 525 | 1915 | 432.8265394622724 | 1.293390460310186 | 7.28e-11 |  | GO:0032502 | Developmental process | 688 | 1917 | 605.1934084995663 | 1.213422866799596 | 4.47e-09
GO:0032502 | Developmental process | 426 | 1916 | 350.6296617519514 | 1.276414644231687 | 1.29e-08 |  | GO:0048513 | Organ development | 271 | 891 | 201.3830008673027 | 1.496796474636694 | 8.76e-10 |  | GO:0065007 | Biological regulation | 947 | 2741 | 865.3287077189939 | 1.144203204821934 | 4.47e-09
GO:0045449 | Regulation of transcription | 343 | 1486 | 271.9392888117953 | 1.339727083877549 | 1.29e-08 |  | GO:0043565 | Sequence-specific DNA binding | 127 | 358 | 80.91483087597571 | 1.882681657048503 | 1.58e-08 |  | GO:0050789 | Regulation of biological process | 877 | 2532 | 799.347788378144 | 1.148622223697753 | 2.11e-08
GO:0006355 | Regulation of transcription, DNA dependent | 330 | 1425 | 260.7762359063313 | 1.345452184639356 | 1.94e-08 |  | GO:0043583 | Ear development | 32 | 57 | 12.88308759757155 | 4.383238679969302 | 8.63e-08 |  | GO:0045449 | Regulation of transcription | 544 | 1487 | 469.4431916738942 | 1.25043991003694 | 3.14e-08
GO:0006351 | Transcription, DNA dependent | 333 | 1442 | 263.887250650477 | 1.340544190359788 | 2.07e-08 |  | GO:0009790 | Embryonic development | 118 | 337 | 76.16843018213356 | 1.845113314199406 | 1.21e-07 |  | GO:0006350 | Transcription | 559 | 1539 | 485.8594969644406 | 1.236406705539359 | 5.86e-08
GO:0032774 | RNA biosynthetic process | 333 | 1445 | 264.4362532523851 | 1.336927614306659 | 2.52e-08 |  | GO:0045165 | Cell fate commitment | 41 | 84 | 18.9856027753686 | 3.265130557389925 | 2.99e-07 |  | GO:0050794 | Regulation of cellular process | 818 | 2356 | 743.7849089332177 | 1.152849426256449 | 5.95e-08
GO:0019219 | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 345 | 1514 | 277.0633130962706 | 1.317567978464195 | 4.51e-08 |  | GO:0048839 | Inner ear development | 29 | 52 | 11.7529921942758 | 4.317728319263238 | 6.4e-07 |  | GO:0019219 | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 550 | 1515 | 478.2827406764961 | 1.235409668052155 | 7.44e-08
GO:0010468 | Regulation of gene expression | 355 | 1566 | 286.5793581960104 | 1.308737833680989 | 4.51e-08 |  | GO:0003677 | DNA binding | 393 | 1444 | 326.3715524718127 | 1.280486442397074 | 7.41e-07 |  | GO:0031323 | Regulation of cellular metabolic process | 587 | 1630 | 514.5880312228968 | 1.219914553327784 | 7.44e-08
GO:0006350 | Transcription | 349 | 1538 | 281.4553339115351 | 1.310424547291722 | 5.5e-08 |  | GO:0007399 | Nervous system development | 158 | 497 | 112.3314830875976 | 1.596035470674663 | 9.58e-07 |  | GO:0009887 | Organ morphogenesis | 169 | 385 | 121.5437987857762 | 1.69593253968254 | 7.77e-08
GO:0003677 | DNA binding | 331 | 1443 | 264.0702515177798 | 1.328898019025538 | 8.61e-08 |  | GO:0048598 | Embryonic morphogenesis | 63 | 156 | 35.25897658282741 | 2.319758373975689 | 1.25e-06 |  | GO:0032774 | RNA biosynthetic process | 527 | 1446 | 456.4995663486557 | 1.242998840115271 | 7.91e-08
GO:0031323 | Regulation of cellular metabolic process | 363 | 1629 | 298.1084128360798 | 1.280092540598818 | 2.61e-07 |  | GO:0007423 | Sensory organ development | 52 | 121 | 27.34830875975716 | 2.580711179329751 | 1.36e-06 |  | GO:0006351 | Transcription, DNA-dependent | 526 | 1443 | 455.5524718126626 | 1.243346075952401 | 7.91e-08
GO:0019222 | Regulatio of metabolic process | 372 | 1683 | 307.990459670425 | 1.266801869706204 | 4.39e-07 |  | GO:0042471 | Ear morphogenesis | 26 | 46 | 10.3968777103209 | 4.451726784343823 | 2.15e-06 |  | [NAME] | Transcription from RNA polymerase II promoter | 153 | 342 | 107.968777103209 | 1.754709576138148 | 7.91e-08
GO:0009887 | Organ morphogenesis | 109 | 385 | 70.45533391153513 | 1.763136204409643 | 5.5e-07 |  | GO:0010468 | Regulation of gene expression | 417 | 1566 | 353.945880312229 | 1.242799805229546 | 2.19e-06 |  | GO:0003677 | DNA binding | 528 | 1446 | 456.4995663486557 | 1.246714070243482 | 1.26e-07
GO:0003676 | Nucleic acid binding | 450 | 2098 | 383.9358196010407 | 1.219056273869231 | 8.58e-07 |  | GO:0007389 | Pattern specific process | 73 | 195 | 44.07372072853425 | 2.049029352188518 | 5.48e-06 |  | [NAME] | Anatomical structure morphogenesis | 315 | 808 | 255.0841283607979 | 1.384966453424871 | 1.39e-07
GO:0016070 | RNA metabolic process | 388 | 1781 | 325.9245446660884 | 1.243509354490802 | 1.18e-06 |  | GO:0031323 | Regulation of cellular metabolic process | 429 | 1629 | 368.1850823937554 | 1.224224865694551 | 5.52e-06 |  | GO:0010468 | Regulation of gene expression | 564 | 1567 | 494.6990459670425 | 1.218859903805068 | 1.46e-07
GO:0050789 | Regulation of biological process | 521 | 2529 | 462.8091934084995 | 1.158357092955194 | 9.88e-06 |  | GO:0022008 | Neurogenesis | 98 | 285 | 64.41543798785777 | 1.794608082540907 | 7.01e-06 |  | GO:0006355 | Regulation of transcription, DNA-dependent | 518 | 1426 | 450.1856027753686 | 1.236572348356489 | 1.72e-07
GO:0043583 | Ear development | 25 | 57 | 10.43104943625325 | 3.487855450236966 | 2.29e-05 |  | GO:0050789 | Regulation of biological process | 633 | 2529 | 571.6022549869905 | 1.143274527137958 | 8.21e-06 |  | GO:0019222 | Regulation of metabolic process | 599 | 1684 | 531.6357328707719 | 1.19666531625057 | 3.26e-07
GO:0050794 | Regulation of cellular process | 486 | 2354 | 430.784041630529 | 1.1615230826999 | 2.45e-05 |  | GO:0045449 | Regulation of transcription | 393 | 1486 | 335.8643538594969 | 1.231282022835613 | 1.3e-05 |  | GO:0006357 | Regulation of transcription from RNA polymerase II promoter | 140 | 313 | 98.81352992194276 | 1.754112939084037 | 3.68e-07
GO:0010467 | Gene expression | 439 | 2100 | 384.3018213356461 | 1.179949268270413 | 2.55e-05 |  | GO:0019219 | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 399 | 1514 | 342.1928881179532 | 1.225414961678637 | 1.52e-05 |  | GO:0016481 | Negative regulation of transcription | 93 | 193 | 60.9297484822203 | 2.015851648351648 | 1.78e-06
GO:0009790 | Embryonic development | 93 | 337 | 61.67129228100607 | 1.701616036050035 | 2.87e-05 |  | GO:0019222 | Regulation of metabolic process | 438 | 1683 | 380.3901127493495 | 1.204730510684334 | 1.59e-05 |  | GO:0007399 | Nervous system development | 202 | 498 | 157.2176929748482 | 1.479228541728542 | 4.39e-06
GO:0065007 | Biological regulation | 555 | 2738 | 501.0563746747615 | 1.135030926178809 | 2.87e-05 |  | GO:0006357 | Regulation of transcription from RNA polymerase II promoter | 104 | 312 | 70.51795316565482 | 1.712202609363008 | 1.65e-05 |  | GO:0031324 | Negative regulation of cellular metabolic process | 106 | 232 | 73.2419774501301 | 1.823521716378859 | 7.66e-06
GO:0048839 | Inner ear development | 23 | 52 | 9.51604509973981 | 3.540774636378493 | 4.73e-05 |  | GO:0042472 | Inner ear morphogenesis | 23 | 42 | 9.4928013876843 | 4.145332633194653 | 2.86e-05 |  | GO:0030900 | Forebrain development | 46 | 80 | 25.25585429314831 | 2.932611506140919 | 7.74e-06
[NAME] | Transcription from RNA polymerase II promoter | 92 | 341 | 62.40329575021682 | 1.64951750128476 | 0.00011 |  | GO:0006350 | Transcription | 402 | 1538 | 347.6173460537727 | 1.211805367894242 | 3.34e-05 |  | GO:0048869 | Cellular developmental process | 425 | 1173 | 370.3139635732871 | 1.231580919080919 | 8.86e-06
GO:0007423 | Sensory organ development | 41 | 121 | 22.14310494362533 | 2.28803317535545 | 0.000131 |  | GO:0065007 | Biological regulation | 674 | 2738 | 618.8402428447529 | 1.118240851463825 | 3.47e-05 |  | GO:0030154 | Cell differentiation | 425 | 1173 | 370.3139635732871 | 1.231580919080919 | 8.86e-06
GO:0006357 | Regulation of transcription from RNA polymerase II promoter | 85 | 312 | 57.09627059843886 | 1.671712215796396 | 0.000164 |  | GO:0032774 | RNA biosynthetic process | 380 | 1445 | 326.5975715524718 | 1.221853505273133 | 3.55e-05 |  | GO:0010467 | Gene expression | 719 | 2102 | 663.5975715524718 | 1.126892088388835 | 1.11e-05
GO:0006139 | Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 472 | 2315 | 423.6470078057242 | 1.143365571793362 | 0.000164 |  | GO:0006351 | Transcription, DNA dependent | 379 | 1442 | 325.9195143104943 | 1.220930929348222 | 3.76e-05 |  | GO:0016070 | RNA metabolic process | 618 | 1782 | 562.5741543798786 | 1.15082984026283 | 1.31e-05
GO:0048598 | Embryonic morphogenesis | 49 | 156 | 28.54813529921943 | 2.04447003587722 | 0.000229 |  | GO:0006355 | Regulation of transcription, DNA dependent | 375 | 1425 | 322.0771899392888 | 1.22300186383072 | 3.76e-05 |  | GO:0045934 | Negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 96 | 208 | 65.6652211621856 | 1.857927786499215 | 1.43e-05
GO:0048869 | Cellular developmental process | 257 | 1171 | 214.2940156114484 | 1.255322679332552 | 0.000257 |  | GO:0048869 | Cellular developmental process | 315 | 1171 | 264.6683434518647 | 1.260149116704083 | 4.04e-05 |  | GO:0001944 | Vasculature development | 73 | 149 | 47.03902862098872 | 2.082019953730481 | 2.13e-05
GO:0030154 | Cell differentiation | 257 | 1171 | 214.2940156114484 | 1.255322679332552 | 0.000257 |  | GO:0030154 | Cell differentiation | 315 | 1171 | 264.6683434518647 | 1.260149116704083 | 4.04e-05 |  | GO:0001568 | Blood vessel development | 72 | 147 | 46.40763226366002 | 2.08087912087912 | 2.56e-05
GO:0042471 | Ear morphogenesis | 20 | 46 | 8.418039895923677 | 3.434196135617937 | 0.000352 |  | [NAME] | Transcription from RNA polymerase II promoter | 109 | 341 | 77.07250650477016 | 1.608880038108345 | 8.71e-05 |  | GO:0007417 | Central nervous system development | 86 | 185 | 58.40416305290546 | 1.882950382950383 | 4.07e-05
GO:0009888 | Tissue development | 52 | 172 | 31.47614917606245 | 1.934597156398104 | 0.000447 |  | GO:0050794 | Regulation of cellular process | 584 | 2354 | 532.0489158716391 | 1.129860252958189 | 9.31e-05 |  | GO:0045892 | Negative regulation of transcription, DNA-dependent | 74 | 156 | 49.24891587163921 | 1.956110962208523 | 9.47e-05
GO:0007399 | Nervous system development | 121 | 497 | 90.95143104943625 | 1.436699606735908 | 0.000974 |  | GO:0048699 | Generation of neurons | 89 | 268 | 60.57311361665221 | 1.70263723165707 | 0.00012 |  | GO:0016564 | Transcription repressor activity | 64 | 127 | 40.09366869037294 | 2.201988487702773 | 0.000109
GO:0042472 | Inner ear morphogenesis | 18 | 42 | 7.686036426712922 | 3.348341232227488 | 0.00147 |  | GO:0007411 | Axon guidance | 31 | 68 | 15.3692974848222 | 2.869096264338014 | 0.000122 |  | GO:0003676 | Nucleic acid binding | 712 | 2101 | 663.2818733738075 | 1.11110056250445 | 0.000194
GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | 36 | 115 | 21.0450997398092 | 2.03443517907493 | 0.00508 |  | GO:0045941 | Positive regulation of transcription | 78 | 229 | 51.75836947094536 | 1.768898060004167 | 0.000157 |  | GO:0048514 | Blood vessel morphogenesis | 62 | 127 | 40.09366869037294 | 2.067540152155537 | 0.0002
GO:0060113 | Inner ear receptor cell differentiation | 10 | 17 | 3.111014744145707 | 6.377792823290455 | 0.0075 |  | GO:0016477 | Cell migration | 69 | 199 | 44.97779705117085 | 1.817568923785348 | 0.00028 |  | GO:0007420 | Brain development | 70 | 148 | 46.72333044232438 | 1.945266272189349 | 0.000209
GO:0045892 | Negative regulation of transcriptionm DNA dependent | 45 | 156 | 28.54813529921943 | 1.809914179582426 | 0.00785 |  | GO:0003002 | Regionalization | 47 | 122 | 27.57432784041631 | 2.145960603734971 | 0.00028 |  | GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | 57 | 115 | 36.3052905464007 | 2.130210306934445 | 0.000259
 |  |  |  |  |  |  |  | GO:0045935 | Positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 78 | 232 | 52.43642671292281 | 1.734439006887203 | 0.00028 |  | GO:0007423 | Sensory organ development | 59 | 121 | 38.19947961838682 | 2.062699397376817 | 0.000352
 |  |  |  |  |  |  |  | GO:0007417 | Central nervous system development | 65 | 185 | 41.81352992194276 | 1.854886160143259 | 0.000287 |  | GO:0048732 | Gland development | 31 | 53 | 16.73200346921075 | 3.05432067932068 | 0.000501
 |  |  |  |  |  |  |  | GO:0001822 | Kidney development | 26 | 55 | 12.43104943625325 | 3.07015640299574 | 0.000291 |  | GO:0048522 | Positive regulation of cellular process | 200 | 522 | 164.7944492627927 | 1.346324482970446 | 0.000501
 |  |  |  |  |  |  |  | GO:0048646 | Anatomical structure function | 51 | 136 | 30.73859496964441 | 2.05464313123561 | 0.000291 |  | GO:0048518 | Positive regulation of biological process | 216 | 572 | 180.5793581960104 | 1.315162365724163 | 0.00068
 |  |  |  |  |  |  |  | GO:0032990 | Cell part morphogenesis | 73 | 215 | 48.59410234171726 | 1.760433668781685 | 0.000325 |  | GO:0001525 | Angiogenesis | 48 | 95 | 29.99132697311362 | 2.213701192424597 | 0.000714
 |  |  |  |  |  |  |  | [NAME] | Cell projection organisation and biogenesis | 73 | 215 | 48.59410234171726 | 1.760433668781685 | 0.000325 |  | GO:0042127 | Regulation of cell proliferation | 93 | 215 | 67.87510841283608 | 1.652337416681679 | 0.000717
 |  |  |  |  |  |  |  | GO:0048858 | Cell projection morphogenesis | 73 | 215 | 48.59410234171726 | 1.760433668781685 | 0.000325 |  | GO:0022008 | Neurogenesis | 118 | 286 | 90.28967909800521 | 1.522468602825746 | 0.00083
 |  |  |  |  |  |  |  | GO:0009888 | Tissue development | 61 | 172 | 38.87528187337381 | 1.881880345426009 | 0.000346 |  | GO:0048519 | Negative regulation of biological process | 240 | 648 | 204.5724197745013 | 1.275048480930834 | 0.00102
 |  |  |  |  |  |  |  | GO:0007409 | Axonogenesis | 48 | 127 | 28.70442324371205 | 2.080651272137327 | 0.000385 |  | GO:0048523 | Negative regulation of cellular process | 227 | 609 | 192.2601908065915 | 1.288065991600023 | 0.00105
 |  |  |  |  |  |  |  | GO:0001655 | Urogenital system development | 27 | 59 | 13.33512575888985 | 2.889341903300077 | 0.000416 |  | GO:0009892 | Negative regulation of metabolic process | 109 | 262 | 82.71292281006072 | 1.544225382460677 | 0.00109
 |  |  |  |  |  |  |  | GO:0048732 | Gland development | 25 | 53 | 11.97901127493495 | 3.057504659576801 | 0.000416 |  | GO:0048699 | Generation of neurons | 111 | 269 | 84.9228100607112 | 1.522795242731951 | 0.00142
 |  |  |  |  |  |  |  | GO:0031325 | Positive regulation of cellular metabolic prcoess | 85 | 263 | 59.44301821335647 | 1.635249683099502 | 0.000585 |  | GO:0035270 | Endocrine system development | 22 | 35 | 11.04943625325239 | 3.66821639898563 | 0.00192
 |  |  |  |  |  |  |  | GO:0048568 | [NAME] organ development | 17 | 31 | 7.006591500433651 | 4.158206337024449 | 0.000635 |  | GO:0045165 | Cell fate commitment | 42 | 84 | 26.51864700780572 | 2.167582417582418 | 0.00332
 |  |  |  |  |  |  |  | GO:0030182 | Neuron differentiation | 77 | 234 | 52.88846487424111 | 1.67948536205034 | 0.000683 |  | GO:0048839 | Inner ear development | 29 | 52 | 16.4163052905464 | 2.733038700430004 | 0.00333
 |  |  |  |  |  |  |  | GO:0007420 | Brain development | 53 | 148 | 33.4508239375542 | 1.910457648341883 | 0.000926 |  | GO:0043583 | Ear development | 31 | 57 | 17.99479618386817 | 2.584425190194422 | 0.00365
 |  |  |  |  |  |  |  | GO:0030900 | Forebrain development | 33 | 80 | 18.081526452732 | 2.404369621658693 | 0.00094 |  | GO:0048598 | Embryonic morphgenesis | 69 | 156 | 49.24891587163921 | 1.719117089806745 | 0.00369
 |  |  |  |  |  |  |  | GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | 55 | 156 | 35.25897658282741 | 1.864775119108227 | 0.0011 |  | GO:0045941 | Positive regulation of transcription | 95 | 230 | 72.6105810928014 | 1.525335775335775 | 0.00504
 |  |  |  |  |  |  |  | GO:0048522 | Positive regulation of cellular process | 149 | 520 | 117.529921942758 | 1.375300209137942 | 0.00117 |  | GO:0048646 | Anatomical structure formation | 61 | 136 | 42.93495229835212 | 1.762967032967033 | 0.00585
 |  |  |  |  |  |  |  | GO:0031128 | Induction | 10 | 13 | 2.938248048568951 | 11.41468406242005 | 0.0012 |  | GO:0030182 | Neuron differentiation | 96 | 235 | 74.18907198612315 | 1.497035338761957 | 0.00747
 |  |  |  |  |  |  |  | GO:0045168 | Cell-cell signalling during cell fate commitment | 10 | 13 | 2.938248048568951 | 11.41468406242005 | 0.0012 |  | GO:0035295 | Tube development | 66 | 151 | 47.67042497831743 | 1.683063994828701 | 0.008
 |  |  |  |  |  |  |  | GO:0048518 | Positive regulation of biological process | 161 | 570 | 128.8308759757155 | 1.347993252359141 | 0.00127 |  | GO:0045935 | Positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 95 | 233 | 73.55767562879444 | 1.492176301958911 | 0.0086
 |  |  |  |  |  |  |  | GO:0009893 | Positive regulation of metabolic process | 87 | 276 | 62.38126626192541 | 1.576313513381818 | 0.00127 |  | GO:0007507 | Heart development | 57 | 127 | 40.09366869037294 | 1.765031397174254 | 0.0091
 |  |  |  |  |  |  |  | GO:0048667 | Neuron morphogenesis during differentiation | 48 | 133 | 30.06053772766695 | 1.933781770574692 | 0.00155
 |  |  |  |  |  |  |  | GO:0048812 | Neurite morphgenesis | 48 | 133 | 30.06053772766695 | 1.933781770574692 | 0.00155
 |  |  |  |  |  |  |  | GO:0045893 | Positive regulation of transcription, DNA dependent | 63 | 187 | 42.26556808326106 | 1.739818780481766 | 0.00155
 |  |  |  |  |  |  |  | GO:0035239 | Tube morphogenesis | 41 | 109 | 24.63607979184735 | 2.064714911290687 | 0.00169
 |  |  |  |  |  |  |  | GO:0042445 | Hormone metabolic process | 17 | 33 | 7.458629661751952 | 3.638430544896393 | 0.002
 |  |  |  |  |  |  |  | [NAME] | Neuron development | 60 | 178 | 40.23139635732871 | 1.74122299257255 | 0.00224
 |  |  |  |  |  |  |  | GO:0006928 | Cell motility | 73 | 227 | 51.30633130962705 | 1.623257019266229 | 0.00241
 |  |  |  |  |  |  |  | GO:0051674 | Localization of cell | 73 | 227 | 51.30633130962705 | 1.623257019266229 | 0.00241
 |  |  |  |  |  |  |  | GO:0003676 | Nucleic acid binding | 519 | 2098 | 474.1880312228968 | 1.125564476579356 | 0.00284
 |  |  |  |  |  |  |  | [NAME] | Induction of an organ | 9 | 12 | 2.712228967909801 | 10.27321565617805 | 0.00364
 |  |  |  |  |  |  |  | [NAME] | Specification of organ identity | 9 | 12 | 2.712228967909801 | 10.27321565617805 | 0.00364
 |  |  |  |  |  |  |  | GO:0009792 | Embryonic development ending in birth or egg hatching | 58 | 175 | 39.55333911535126 | 1.697568399026572 | 0.00508
 |  |  |  |  |  |  |  | GO:0031175 | Neurite development | 53 | 157 | 35.48499566348656 | 1.745129582619989 | 0.00553
 |  |  |  |  |  |  |  | GO:0043009 | Chordate embryonic development | 57 | 172 | 38.87528187337381 | 1.697313891020721 | 0.00572
 |  |  |  |  |  |  |  | GO:0035295 | Tube development | 51 | 151 | 34.12888117953166 | 1.746446661550269 | 0.0072
 |  |  |  |  |  |  |  | GO:0001763 | Morphogenesis of a branching structure | 22 | 51 | 11.52697311361665 | 2.597824648688702 | 0.0082