Spreadsheet: 00b6a8c4-2a5b-458d-adfd-4f03f229903b
Sheet: Supplementary Table S4.txt

Annotation Cluster 1 | Enrichment Score: 3.5198559988079525
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0043232~intracellular non-membrane-bounded organelle | 30 | 28.3018867924528 | 0.000109531623179353 | MYL6, HMGN1, RPL36A, [NAME], VIM, RBM5, TPM1, FOS, ACTG2, LOC100291837, PBXIP1, NPM1, RPS21, TUBA1B, TUBA1C, INO80B, ACTB, PABPN1, ACTC1, [NAME], ACTN1, MYH7, TMSB10, [NAME], C19ORF33, PGM5, RPL18A, NOP56, ABL1, MYH10 | 74 | 2596 | 12782 | 1.99610627576729 | 0.0243447329930662 | 0.0081816681316531 | 0.139841056740697
GOTERM_CC_FAT | GO:0043228~non-membrane-bounded organelle | 30 | 28.3018867924528 | 0.000109531623179353 | MYL6, HMGN1, RPL36A, [NAME], VIM, RBM5, TPM1, FOS, ACTG2, LOC100291837, PBXIP1, NPM1, RPS21, TUBA1B, TUBA1C, INO80B, ACTB, PABPN1, ACTC1, [NAME], ACTN1, MYH7, TMSB10, [NAME], C19ORF33, PGM5, RPL18A, NOP56, ABL1, MYH10 | 74 | 2596 | 12782 | 1.99610627576729 | 0.0243447329930662 | 0.0081816681316531 | 0.139841056740697
GOTERM_CC_FAT | GO:0015629~[NAME] | 9 | 8.49056603773585 | 0.000142750839725294 | MYL6, ACTG2, ACTC1, PGM5, [NAME], [NAME], [NAME], TPM1, MYH10 | 74 | 269 | 12782 | 5.77906158947051 | 0.0316108244637873 | 0.00799815112605517 | 0.182217010616048
GOTERM_CC_FAT | GO:0005856~cytoskeleton | 20 | 18.8679245283018 | 0.000201324129091771 | MYL6, ACTB, RPL36A, ACTC1, [NAME], [NAME], VIM, ACTN1, TMSB10, [NAME], [NAME], TPM1, ACTG2, PGM5, PBXIP1, NPM1, ABL1, TUBA1B, TUBA1C, MYH10 | 74 | 1381 | 12782 | 2.50151672309528 | 0.0442916535781769 | 0.00752198212892707 | 0.25689540507553
GOTERM_CC_FAT | GO:0044430~cytoskeletal part | 13 | 12.2641509433962 | 0.00729737152972391 | MYL6, ACTC1, [NAME], VIM, [NAME], [NAME], TPM1, PGM5, PBXIP1, NPM1, TUBA1B, TUBA1C, MYH10 | 74 | 952 | 12782 | 2.35870429252782 | 0.807551887668841 | 0.119058226640559 | 8.93246524567268
Annotation Cluster 2 | Enrichment Score: 3.0453057857068915
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | muscle protein | 7 | 6.60377358490566 | 9.03032177408998e-07 | MYL6, ACTG2, ACTC1, TAGLN, [NAME], [NAME], TPM1 | 106 | 60 | 19235 | 21.1705974842767 | 0.000195938872438405 | 9.79742356946866e-05 | 0.00114695890711669
GOTERM_CC_FAT | GO:0044449~contractile fiber part | 8 | 7.54716981132075 | 3.5258405812677e-06 | ACTG2, ACTC1, PGM5, [NAME], ACTN1, MYH7, TPM1, ENO1 | 74 | 113 | 12782 | 12.2286534321932 | 0.000793000937770904 | 0.000793000937770904 | 0.00450431632862402
GOTERM_CC_FAT | GO:0043292~contractile fiber | 8 | 7.54716981132075 | 5.55934698396142e-06 | ACTG2, ACTC1, PGM5, [NAME], ACTN1, MYH7, TPM1, ENO1 | 74 | 121 | 12782 | 11.4201474201474 | 0.00125007455340886 | 0.000625232734690728 | 0.0071020674400235
GOTERM_BP_FAT | GO:0006936~muscle contraction | 8 | 7.54716981132075 | 3.02522342434851e-05 | MYL6, PABPN1, ACTG2, ACTC1, [NAME], [NAME], [NAME], TPM1 | 80 | 153 | 13528 | 8.84183006535947 | 0.0240297399061637 | 0.0120879289664306 | 0.0464576239919134
GOTERM_BP_FAT | GO:0003012~muscle system process | 8 | 7.54716981132075 | 5.49791719550193e-05 | MYL6, PABPN1, ACTG2, ACTC1, [NAME], [NAME], [NAME], TPM1 | 80 | 168 | 13528 | 8.05238095238095 | 0.0432416903502596 | 0.014626796868886 | 0.0844151964679573
INTERPRO | IPR004001:[NAME], conserved site | 4 | 3.77358490566037 | 9.23778369096894e-05 | ACTB, ACTG2, ACTC1, ACTA2 | 95 | 16 | 16659 | 43.8394736842105 | 0.0214758329973682 | 0.0214758329973682 | 0.118773707864527
GOTERM_CC_FAT | GO:0015629~[NAME] | 9 | 8.49056603773585 | 0.000142750839725294 | MYL6, ACTG2, ACTC1, PGM5, [NAME], [NAME], [NAME], TPM1, MYH10 | 74 | 269 | 12782 | 5.77906158947051 | 0.0316108244637873 | 0.00799815112605517 | 0.182217010616048
SP_PIR_KEYWORDS | methylated amino acid | 4 | 3.77358490566037 | 0.000168415841068172 | ACTB, ACTG2, ACTC1, ACTA2 | 106 | 20 | 19235 | 36.2924528301886 | 0.0358894527155274 | 0.00607303666631475 | 0.213698751433621
GOTERM_CC_FAT | GO:0030485~smooth muscle contractile fiber | 3 | 2.83018867924528 | 0.000191611092115399 | ACTG2, ACTC1, ACTA2 | 74 | 4 | 12782 | 129.547297297297 | 0.0422003214340167 | 0.00858625110830391 | 0.244515268547351
PIR_SUPERFAMILY | PIRSF002337:[NAME] | 4 | 3.77358490566037 | 0.000220126251167703 | ACTB, ACTG2, ACTC1, ACTA2 | 54 | 17 | 7396 | 32.2265795206971 | 0.0124701724043738 | 0.0124701724043738 | 0.217979732459006
GOTERM_BP_FAT | GO:0006939~smooth muscle contraction | 4 | 3.77358490566037 | 0.000921803273998208 | ACTG2, ACTC1, [NAME], [NAME] | 80 | 33 | 13528 | 20.4969696969696 | 0.523587703390209 | 0.0885184749382747 | 1.4065655967464
GOTERM_BP_FAT | GO:0014829~vascular smooth muscle contraction | 3 | 2.83018867924528 | 0.00118044101878533 | ACTG2, ACTC1, ACTA2 | 80 | 9 | 13528 | 56.3666666666666 | 0.613117861339383 | 0.100139043526444 | 1.79788125692597
SMART | SM00268:ACTIN | 4 | 3.77358490566037 | 0.00124934331296996 | ACTB, ACTG2, ACTC1, ACTA2 | 51 | 39 | 9079 | 18.2584213172448 | 0.0687775470011873 | 0.0350013196906368 | 1.23150299243599
INTERPRO | IPR004000:[NAME]/actin-like | 4 | 3.77358490566037 | 0.00137243315110153 | ACTB, ACTG2, ACTC1, ACTA2 | 95 | 39 | 16659 | 17.9854251012145 | 0.275840287112689 | 0.0625095075754251 | 1.7512536548099
SP_PIR_KEYWORDS | cytoskeleton | 11 | 10.377358490566 | 0.00250458630491974 | ACTB, ACTG2, ACTC1, PGM5, PBXIP1, [NAME], ACTN1, TMSB10, [NAME], ABL1, TPM1 | 106 | 636 | 19235 | 3.13849827934021 | 0.419680800058559 | 0.0482668943802526 | 3.13494043955164
GOTERM_BP_FAT | GO:0042310~vasoconstriction | 3 | 2.83018867924528 | 0.00432642024248524 | ACTG2, ACTC1, ACTA2 | 80 | 17 | 13528 | 29.8411764705882 | 0.969376520163822 | 0.220419372288586 | 6.44291411618165
GOTERM_BP_FAT | GO:0008217~regulation of blood pressure | 4 | 3.77358490566037 | 0.0206731338235674 | ACTG2, ACTC1, ACTA2, TPM1 | 80 | 100 | 13528 | 6.764 | 0.999999949202104 | 0.503319734111159 | 27.4482085450514
GOTERM_BP_FAT | GO:0050880~regulation of blood vessel size | 3 | 2.83018867924528 | 0.0383019628093907 | ACTG2, ACTC1, ACTA2 | 80 | 53 | 13528 | 9.57169811320754 | 0.999999999999976 | 0.648894239507459 | 45.1125197098268
GOTERM_BP_FAT | GO:0035150~regulation of tube size | 3 | 2.83018867924528 | 0.0383019628093907 | ACTG2, ACTC1, ACTA2 | 80 | 53 | 13528 | 9.57169811320754 | 0.999999999999976 | 0.648894239507459 | 45.1125197098268
GOTERM_BP_FAT | GO:0003018~vascular process in circulatory system | 3 | 2.83018867924528 | 0.0451001335437081 | ACTG2, ACTC1, ACTA2 | 80 | 58 | 13528 | 8.74655172413793 | 0.999999999999999 | 0.64322731662418 | 50.7790007767576
GOTERM_BP_FAT | GO:0003013~circulatory system process | 4 | 3.77358490566037 | 0.095011396502232 | ACTG2, ACTC1, ACTA2, TPM1 | 80 | 186 | 13528 | 3.63655913978494 | 1 | 0.812166913267661 | 78.4208616593927
GOTERM_BP_FAT | GO:0008015~blood circulation | 4 | 3.77358490566037 | 0.095011396502232 | ACTG2, ACTC1, ACTA2, TPM1 | 80 | 186 | 13528 | 3.63655913978494 | 1 | 0.812166913267661 | 78.4208616593927
UP_SEQ_FEATURE | propeptide:Removed in mature form | 4 | 3.77358490566037 | 0.131856599824535 | ACTG2, ACTC1, [NAME], RHOB | 106 | 229 | 19113 | 3.14954272060641 | 1 | 0.996217538025833 | 85.6001657404962
Annotation Cluster 3 | Enrichment Score: 2.476825098852253
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0042641~actomyosin | 4 | 3.77358490566037 | 0.000473742149041331 | ACTC1, PGM5, TPM1, MYH10 | 74 | 27 | 12782 | 25.5895895895895 | 0.101130341557375 | 0.0117764681452449 | 0.603540287071902
GOTERM_CC_FAT | GO:0001725~stress fiber | 3 | 2.83018867924528 | 0.00818654682047916 | PGM5, TPM1, MYH10 | 74 | 24 | 12782 | 21.5912162162162 | 0.842692711910616 | 0.123756281983116 | 9.9690815036221
GOTERM_CC_FAT | GO:0032432~actin filament bundle | 3 | 2.83018867924528 | 0.00956933872747647 | PGM5, TPM1, MYH10 | 74 | 26 | 12782 | 19.9303534303534 | 0.885074281781533 | 0.134312496372964 | 11.5595753133077
Annotation Cluster 4 | Enrichment Score: 2.475241358524568
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | muscle protein | 7 | 6.60377358490566 | 9.03032177408998e-07 | MYL6, ACTG2, ACTC1, TAGLN, [NAME], [NAME], TPM1 | 106 | 60 | 19235 | 21.1705974842767 | 0.000195938872438405 | 9.79742356946866e-05 | 0.00114695890711669
GOTERM_CC_FAT | GO:0044449~contractile fiber part | 8 | 7.54716981132075 | 3.5258405812677e-06 | ACTG2, ACTC1, PGM5, [NAME], ACTN1, MYH7, TPM1, ENO1 | 74 | 113 | 12782 | 12.2286534321932 | 0.000793000937770904 | 0.000793000937770904 | 0.00450431632862402
GOTERM_CC_FAT | GO:0043292~contractile fiber | 8 | 7.54716981132075 | 5.55934698396142e-06 | ACTG2, ACTC1, PGM5, [NAME], ACTN1, MYH7, TPM1, ENO1 | 74 | 121 | 12782 | 11.4201474201474 | 0.00125007455340886 | 0.000625232734690728 | 0.0071020674400235
GOTERM_BP_FAT | [NAME]-based movement | 5 | 4.71698113207547 | 8.76645929148979e-06 | MYL6, ACTC1, MYH7, TPM1, MYH10 | 80 | 23 | 13528 | 36.7608695652173 | 0.00702348340532033 | 0.00702348340532033 | 0.0134645163020197
GOTERM_BP_FAT | GO:0006936~muscle contraction | 8 | 7.54716981132075 | 3.02522342434851e-05 | MYL6, PABPN1, ACTG2, ACTC1, [NAME], [NAME], [NAME], TPM1 | 80 | 153 | 13528 | 8.84183006535947 | 0.0240297399061637 | 0.0120879289664306 | 0.0464576239919134
GOTERM_BP_FAT | GO:0003012~muscle system process | 8 | 7.54716981132075 | 5.49791719550193e-05 | MYL6, PABPN1, ACTG2, ACTC1, [NAME], [NAME], [NAME], TPM1 | 80 | 168 | 13528 | 8.05238095238095 | 0.0432416903502596 | 0.014626796868886 | 0.0844151964679573
GOTERM_BP_FAT | GO:0030029~actin filament-based process | 9 | 8.49056603773585 | 7.92483485516823e-05 | MYL6, ACTC1, [NAME], ACTN1, TMSB10, [NAME], ABL1, TPM1, MYH10 | 80 | 241 | 13528 | 6.3149377593361 | 0.0617306306447806 | 0.0158033450068614 | 0.121656969255778
GOTERM_CC_FAT | GO:0015629~[NAME] | 9 | 8.49056603773585 | 0.000142750839725294 | MYL6, ACTG2, ACTC1, PGM5, [NAME], [NAME], [NAME], TPM1, MYH10 | 74 | 269 | 12782 | 5.77906158947051 | 0.0316108244637873 | 0.00799815112605517 | 0.182217010616048
GOTERM_BP_FAT | GO:0030705~cytoskeleton-dependent intracellular transport | 5 | 4.71698113207547 | 0.00023572220135013 | MYL6, ACTC1, MYH7, TPM1, MYH10 | 80 | 52 | 13528 | 16.2596153846153 | 0.172662851512032 | 0.0310967317271201 | 0.361459353802673
GOTERM_CC_FAT | GO:0030017~sarcomere | 6 | 5.66037735849056 | 0.000237769103593902 | ACTC1, PGM5, ACTN1, MYH7, TPM1, ENO1 | 74 | 98 | 12782 | 10.5752895752895 | 0.0520982386914458 | 0.00761434989491605 | 0.303335168109542
GOTERM_CC_FAT | GO:0030016~myofibril | 6 | 5.66037735849056 | 0.000423699820664348 | ACTC1, PGM5, ACTN1, MYH7, TPM1, ENO1 | 74 | 111 | 12782 | 9.33674214755296 | 0.0909477098385524 | 0.0118483317992558 | 0.539946093297838
GOTERM_CC_FAT | GO:0042641~actomyosin | 4 | 3.77358490566037 | 0.000473742149041331 | ACTC1, PGM5, TPM1, MYH10 | 74 | 27 | 12782 | 25.5895895895895 | 0.101130341557375 | 0.0117764681452449 | 0.603540287071902
GOTERM_BP_FAT | GO:0031032~actomyosin structure organization | 4 | 3.77358490566037 | 0.000565226020781994 | ACTC1, CNN3, TPM1, MYH10 | 80 | 28 | 13528 | 24.1571428571428 | 0.365279287876111 | 0.0628749989497117 | 0.864677903025534
GOTERM_MF_FAT | GO:0030898~actin-dependent ATPase activity | 3 | 2.83018867924528 | 0.00105059353710173 | MYL6, [NAME], MYH10 | 82 | 8 | 12983 | 59.3734756097561 | 0.191303390208505 | 0.100724397199893 | 1.31097971044658
GOTERM_BP_FAT | GO:0030049~muscle filament sliding | 3 | 2.83018867924528 | 0.00118044101878533 | MYL6, [NAME], TPM1 | 80 | 9 | 13528 | 56.3666666666666 | 0.613117861339383 | 0.100139043526444 | 1.79788125692597
GOTERM_BP_FAT | GO:0033275~[NAME] filament sliding | 3 | 2.83018867924528 | 0.00118044101878533 | MYL6, [NAME], TPM1 | 80 | 9 | 13528 | 56.3666666666666 | 0.613117861339383 | 0.100139043526444 | 1.79788125692597
GOTERM_BP_FAT | GO:0070252~actin-mediated cell contraction | 3 | 2.83018867924528 | 0.00118044101878533 | MYL6, [NAME], TPM1 | 80 | 9 | 13528 | 56.3666666666666 | 0.613117861339383 | 0.100139043526444 | 1.79788125692597
GOTERM_BP_FAT | GO:0048738~cardiac muscle tissue development | 4 | 3.77358490566037 | 0.00447136057444509 | ACTC1, MYH7, TPM1, MYH10 | 80 | 57 | 13528 | 11.8666666666666 | 0.9727590835017 | 0.213531291889573 | 6.65188652966616
GOTERM_BP_FAT | GO:0014706~striated muscle tissue development | 5 | 4.71698113207547 | 0.00514944696867088 | MYL6, ACTC1, MYH7, TPM1, MYH10 | 80 | 119 | 13528 | 7.10504201680672 | 0.98424900678662 | 0.228507432386365 | 7.62375612665175
GOTERM_BP_FAT | GO:0060537~muscle tissue development | 5 | 4.71698113207547 | 0.0061218995117029 | MYL6, ACTC1, MYH7, TPM1, MYH10 | 80 | 125 | 13528 | 6.76399999999999 | 0.9928248742855 | 0.252050416984515 | 9.00102669402183
GOTERM_CC_FAT | GO:0044430~cytoskeletal part | 13 | 12.2641509433962 | 0.00729737152972391 | MYL6, ACTC1, [NAME], VIM, [NAME], [NAME], TPM1, PGM5, PBXIP1, NPM1, TUBA1B, TUBA1C, MYH10 | 74 | 952 | 12782 | 2.35870429252782 | 0.807551887668841 | 0.119058226640559 | 8.93246524567268
GOTERM_BP_FAT | GO:0007517~muscle organ development | 6 | 5.66037735849056 | 0.00780088925377032 | MYL6, ACTC1, TAGLN, [NAME], TPM1, MYH10 | 80 | 211 | 13528 | 4.8085308056872 | 0.998157268301363 | 0.282078510925042 | 11.3338681136793
GOTERM_BP_FAT | GO:0060415~muscle tissue morphogenesis | 3 | 2.83018867924528 | 0.0107527766170198 | ACTC1, MYH7, TPM1 | 80 | 27 | 13528 | 18.7888888888888 | 0.999832084289971 | 0.338937617817536 | 15.3002944116117
GOTERM_BP_FAT | GO:0055008~cardiac muscle tissue morphogenesis | 3 | 2.83018867924528 | 0.0107527766170198 | ACTC1, MYH7, TPM1 | 80 | 27 | 13528 | 18.7888888888888 | 0.999832084289971 | 0.338937617817536 | 15.3002944116117
KEGG_PATHWAY | hsa04260:Cardiac muscle contraction | 4 | 3.77358490566037 | 0.0228395667311678 | ACTC1, ATP1B3, [NAME], TPM1 | 41 | 78 | 5085 | 6.36022514071294 | 0.72578645035224 | 0.276360562007334 | 20.398863448521
GOTERM_MF_FAT | GO:0008307~structural constituent of muscle | 3 | 2.83018867924528 | 0.0281753775416485 | MYL6, [NAME], TPM1 | 82 | 42 | 12983 | 11.3092334494773 | 0.99689003533588 | 0.5616487919209 | 30.148828087275
SP_PIR_KEYWORDS | [NAME] | 3 | 2.83018867924528 | 0.0282869037333349 | ACTC1, MYH7, TPM1 | 106 | 48 | 19235 | 11.3413915094339 | 0.998024131004549 | 0.359026805640233 | 30.5427531497513
KEGG_PATHWAY | hsa05410:[NAME] cardiomyopathy (HCM) | 4 | 3.77358490566037 | 0.0285579339434937 | ACTB, ACTC1, MYH7, TPM1 | 41 | 85 | 5085 | 5.8364418938307 | 0.802600195961301 | 0.277114783127179 | 24.8809988199589
GOTERM_BP_FAT | GO:0006941~striated muscle contraction | 3 | 2.83018867924528 | 0.029528174162829 | ACTC1, MYH7, TPM1 | 80 | 46 | 13528 | 11.0282608695652 | 0.99999999996578 | 0.577113148217126 | 36.8960407523826
SP_PIR_KEYWORDS | [NAME] | 3 | 2.83018867924528 | 0.0316386736036826 | MYL6, [NAME], MYH10 | 106 | 51 | 19235 | 10.6742508324084 | 0.999066479739556 | 0.336605318866215 | 33.5250831266571
KEGG_PATHWAY | hsa05414:Dilated cardiomyopathy | 4 | 3.77358490566037 | 0.0349715508186587 | ACTB, ACTC1, MYH7, TPM1 | 41 | 92 | 5085 | 5.39236479321314 | 0.863778226708423 | 0.282688563792279 | 29.6371681475815
GOTERM_MF_FAT | GO:0008092~cytoskeletal protein binding | 8 | 7.54716981132075 | 0.037584188204834 | ACTC1, TAGLN, [NAME], ACTN1, TMSB10, [NAME], TPM1, MYH10 | 82 | 504 | 12983 | 2.51316298877274 | 0.999564211860777 | 0.619889885786057 | 38.1799214227528
GOTERM_CC_FAT | GO:0031674~I band | 3 | 2.83018867924528 | 0.0393305909311888 | ACTC1, PGM5, ACTN1 | 74 | 55 | 12782 | 9.42162162162162 | 0.999880011024697 | 0.36326742727258 | 40.1071444795051
GOTERM_CC_FAT | GO:0016459~myosin complex | 3 | 2.83018867924528 | 0.0531302185899175 | MYL6, [NAME], MYH10 | 74 | 65 | 12782 | 7.97214137214137 | 0.999995372912226 | 0.427844617228397 | 50.2150537297698
GOTERM_MF_FAT | GO:0016887~ATPase activity | 6 | 5.66037735849056 | 0.0575051900968681 | MYL6, ABCF3, ACTC1, ATP1B3, [NAME], MYH10 | 82 | 334 | 12983 | 2.84423835256316 | 0.999993626890211 | 0.662970195006619 | 52.4568170375427
GOTERM_BP_FAT | GO:0003007~heart morphogenesis | 3 | 2.83018867924528 | 0.0678330028969478 | ACTC1, MYH7, TPM1 | 80 | 73 | 13528 | 6.94931506849315 | 1 | 0.747780101541656 | 66.0045559926504
GOTERM_BP_FAT | GO:0007507~heart development | 4 | 3.77358490566037 | 0.130923055063469 | ACTC1, MYH7, TPM1, MYH10 | 80 | 215 | 13528 | 3.1460465116279 | 1 | 0.871429269497148 | 88.4141294281848
SP_PIR_KEYWORDS | motor protein | 3 | 2.83018867924528 | 0.162366414913186 | MYL6, [NAME], MYH10 | 106 | 132 | 19235 | 4.12414236706689 | 1 | 0.699246635437492 | 89.463663820045
KEGG_PATHWAY | hsa04270:Vascular smooth muscle contraction | 3 | 2.83018867924528 | 0.21987015729688 | MYL6, ACTG2, [NAME] | 41 | 112 | 5085 | 3.3220818815331 | 0.999999085158358 | 0.686109026449031 | 91.3857906501511
GOTERM_MF_FAT | GO:0003774~motor activity | 3 | 2.83018867924528 | 0.221993602971911 | MYL6, [NAME], MYH10 | 82 | 142 | 12983 | 3.3449845413947 | 1 | 0.93066078140767 | 95.7208183614372
GOTERM_MF_FAT | GO:0042623~ATPase activity, coupled | 4 | 3.77358490566037 | 0.240848475925987 | MYL6, ATP1B3, [NAME], MYH10 | 82 | 272 | 12983 | 2.32837159253945 | 1 | 0.920347803955286 | 96.8551674925859
GOTERM_BP_FAT | GO:0048729~tissue morphogenesis | 3 | 2.83018867924528 | 0.283212467392177 | ACTC1, MYH7, TPM1 | 80 | 180 | 13528 | 2.81833333333333 | 1 | 0.971830084299047 | 99.3991257168881
Annotation Cluster 5 | Enrichment Score: 2.036534549717917
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0044449~contractile fiber part | 8 | 7.54716981132075 | 3.5258405812677e-06 | ACTG2, ACTC1, PGM5, [NAME], ACTN1, MYH7, TPM1, ENO1 | 74 | 113 | 12782 | 12.2286534321932 | 0.000793000937770904 | 0.000793000937770904 | 0.00450431632862402
GOTERM_CC_FAT | GO:0043292~contractile fiber | 8 | 7.54716981132075 | 5.55934698396142e-06 | ACTG2, ACTC1, PGM5, [NAME], ACTN1, MYH7, TPM1, ENO1 | 74 | 121 | 12782 | 11.4201474201474 | 0.00125007455340886 | 0.000625232734690728 | 0.0071020674400235
GOTERM_CC_FAT | GO:0030017~sarcomere | 6 | 5.66037735849056 | 0.000237769103593902 | ACTC1, PGM5, ACTN1, MYH7, TPM1, ENO1 | 74 | 98 | 12782 | 10.5752895752895 | 0.0520982386914458 | 0.00761434989491605 | 0.303335168109542
GOTERM_CC_FAT | GO:0030016~myofibril | 6 | 5.66037735849056 | 0.000423699820664348 | ACTC1, PGM5, ACTN1, MYH7, TPM1, ENO1 | 74 | 111 | 12782 | 9.33674214755296 | 0.0909477098385524 | 0.0118483317992558 | 0.539946093297838
GOTERM_CC_FAT | GO:0005925~focal adhesion | 3 | 2.83018867924528 | 0.115239063997288 | PGM5, ACTN1, MYH7 | 74 | 102 | 12782 | 5.08028616852146 | 0.999999999998914 | 0.639518627170221 | 79.0743488333706
GOTERM_CC_FAT | [NAME]cell-substrate adherens junction | 3 | 2.83018867924528 | 0.122746334785719 | PGM5, ACTN1, MYH7 | 74 | 106 | 12782 | 4.88857725650178 | 0.99999999999984 | 0.650883569919403 | 81.232761767067
GOTERM_CC_FAT | GO:0030055~cell-substrate junction | 3 | 2.83018867924528 | 0.134223654398539 | PGM5, ACTN1, MYH7 | 74 | 112 | 12782 | 4.62668918918918 | 0.999999999999991 | 0.648693125333167 | 84.1389600050485
GOTERM_CC_FAT | GO:0005912~adherens junction | 3 | 2.83018867924528 | 0.221721123611547 | PGM5, ACTN1, MYH7 | 74 | 155 | 12782 | 3.34315605928509 | 1 | 0.773323736363397 | 95.9336300872367
GOTERM_CC_FAT | GO:0070161~anchoring junction | 3 | 2.83018867924528 | 0.257652942605 | PGM5, ACTN1, MYH7 | 74 | 172 | 12782 | 3.01272784412319 | 1 | 0.797314272543403 | 97.7769469832377
GOTERM_CC_FAT | GO:0016323~basolateral plasma membrane | 3 | 2.83018867924528 | 0.323247928604097 | PGM5, ACTN1, MYH7 | 74 | 203 | 12782 | 2.55265610438024 | 1 | 0.833520647004632 | 99.3181848540467
GOTERM_CC_FAT | GO:0030054~cell junction | 4 | 3.77358490566037 | 0.572538317131892 | PGM5, DENND1A, ACTN1, MYH7 | 74 | 518 | 12782 | 1.33382030679327 | 1 | 0.956493393137219 | 99.9980744439355
Annotation Cluster 6 | Enrichment Score: 2.0237568572410956
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | [NAME]-based movement | 5 | 4.71698113207547 | 8.76645929148979e-06 | MYL6, ACTC1, MYH7, TPM1, MYH10 | 80 | 23 | 13528 | 36.7608695652173 | 0.00702348340532033 | 0.00702348340532033 | 0.0134645163020197
GOTERM_BP_FAT | GO:0030029~actin filament-based process | 9 | 8.49056603773585 | 7.92483485516823e-05 | MYL6, ACTC1, [NAME], ACTN1, TMSB10, [NAME], ABL1, TPM1, MYH10 | 80 | 241 | 13528 | 6.3149377593361 | 0.0617306306447806 | 0.0158033450068614 | 0.121656969255778
GOTERM_BP_FAT | GO:0030705~cytoskeleton-dependent intracellular transport | 5 | 4.71698113207547 | 0.00023572220135013 | MYL6, ACTC1, MYH7, TPM1, MYH10 | 80 | 52 | 13528 | 16.2596153846153 | 0.172662851512032 | 0.0310967317271201 | 0.361459353802673
GOTERM_CC_FAT | GO:0042641~actomyosin | 4 | 3.77358490566037 | 0.000473742149041331 | ACTC1, PGM5, TPM1, MYH10 | 74 | 27 | 12782 | 25.5895895895895 | 0.101130341557375 | 0.0117764681452449 | 0.603540287071902
GOTERM_BP_FAT | GO:0031032~actomyosin structure organization | 4 | 3.77358490566037 | 0.000565226020781994 | ACTC1, CNN3, TPM1, MYH10 | 80 | 28 | 13528 | 24.1571428571428 | 0.365279287876111 | 0.0628749989497117 | 0.864677903025534
SP_PIR_KEYWORDS | [NAME] binding | 4 | 3.77358490566037 | 0.00134842244202184 | TAGLN, [NAME], ACTN1, TPM1 | 106 | 40 | 19235 | 18.1462264150943 | 0.253832465427148 | 0.0359389349131739 | 1.6992202169782
GOTERM_BP_FAT | GO:0030036~actin cytoskeleton organization | 7 | 6.60377358490566 | 0.00204871633836935 | ACTC1, [NAME], ACTN1, TMSB10, ABL1, TPM1, MYH10 | 80 | 226 | 13528 | 5.23761061946902 | 0.807730555514934 | 0.128382671192669 | 3.10097746557531
SP_PIR_KEYWORDS | actin-binding | 7 | 6.60377358490566 | 0.0023560835867116 | TAGLN, [NAME], ACTN1, TMSB10, [NAME], TPM1, MYH10 | 106 | 247 | 19235 | 5.14265525933847 | 0.400628326689719 | 0.0552876793270828 | 2.95161789091927
GOTERM_BP_FAT | [NAME]~cytoskeleton organization | 9 | 8.49056603773585 | 0.00385343712292879 | ACTC1, [NAME], NPM1, ACTN1, TMSB10, ABL1, TPM1, TUBA1B, MYH10 | 80 | 436 | 13528 | 3.49059633027522 | 0.955137279843695 | 0.212412358942845 | 5.75792903361183
GOTERM_BP_FAT | GO:0048738~cardiac muscle tissue development | 4 | 3.77358490566037 | 0.00447136057444509 | ACTC1, MYH7, TPM1, MYH10 | 80 | 57 | 13528 | 11.8666666666666 | 0.9727590835017 | 0.213531291889573 | 6.65188652966616
GOTERM_BP_FAT | GO:0014706~striated muscle tissue development | 5 | 4.71698113207547 | 0.00514944696867088 | MYL6, ACTC1, MYH7, TPM1, MYH10 | 80 | 119 | 13528 | 7.10504201680672 | 0.98424900678662 | 0.228507432386365 | 7.62375612665175
GOTERM_BP_FAT | GO:0060537~muscle tissue development | 5 | 4.71698113207547 | 0.0061218995117029 | MYL6, ACTC1, MYH7, TPM1, MYH10 | 80 | 125 | 13528 | 6.76399999999999 | 0.9928248742855 | 0.252050416984515 | 9.00102669402183
GOTERM_BP_FAT | GO:0030239~myofibril assembly | 3 | 2.83018867924528 | 0.00658036587065901 | ACTC1, TPM1, MYH10 | 80 | 21 | 13528 | 24.1571428571428 | 0.99504866474675 | 0.255389735819401 | 9.64366538485151
GOTERM_BP_FAT | GO:0007517~muscle organ development | 6 | 5.66037735849056 | 0.00780088925377032 | MYL6, ACTC1, TAGLN, [NAME], TPM1, MYH10 | 80 | 211 | 13528 | 4.8085308056872 | 0.998157268301363 | 0.282078510925042 | 11.3338681136793
GOTERM_MF_FAT | [NAME] | 7 | 6.60377358490566 | 0.0160759538019057 | TAGLN, [NAME], ACTN1, TMSB10, [NAME], TPM1, MYH10 | 82 | 326 | 12983 | 3.39970821487356 | 0.962134993088947 | 0.480425763516268 | 18.4100069513066
GOTERM_BP_FAT | GO:0010927~cellular component assembly involved in morphogenesis | 3 | 2.83018867924528 | 0.018658491412563 | ACTC1, TPM1, MYH10 | 80 | 36 | 13528 | 14.0916666666666 | 0.999999734896279 | 0.497582965695347 | 25.1215188697225
GOTERM_BP_FAT | GO:0055002~striated muscle cell development | 3 | 2.83018867924528 | 0.0369939677045364 | ACTC1, TPM1, MYH10 | 80 | 52 | 13528 | 9.75576923076923 | 0.999999999999931 | 0.648335646956142 | 43.9545941740216
GOTERM_MF_FAT | GO:0008092~cytoskeletal protein binding | 8 | 7.54716981132075 | 0.037584188204834 | ACTC1, TAGLN, [NAME], ACTN1, TMSB10, [NAME], TPM1, MYH10 | 82 | 504 | 12983 | 2.51316298877274 | 0.999564211860777 | 0.619889885786057 | 38.1799214227528
GOTERM_BP_FAT | GO:0055001~muscle cell development | 3 | 2.83018867924528 | 0.0423301900930974 | ACTC1, TPM1, MYH10 | 80 | 56 | 13528 | 9.05892857142857 | 0.999999999999999 | 0.640408978265064 | 48.5396337598464
SMART | SM00033:CH | 3 | 2.83018867924528 | 0.0566310039852048 | TAGLN, [NAME], ACTN1 | 51 | 70 | 9079 | 7.62941176470588 | 0.963954492716118 | 0.564274692083945 | 43.8901847566465
INTERPRO | IPR001715:[NAME]-like actin-binding | 3 | 2.83018867924528 | 0.0594119413426449 | TAGLN, [NAME], ACTN1 | 95 | 70 | 16659 | 7.51533834586466 | 0.999999439115691 | 0.797963253795907 | 54.5222198216483
GOTERM_BP_FAT | GO:0051146~striated muscle cell differentiation | 3 | 2.83018867924528 | 0.0935119486378215 | ACTC1, TPM1, MYH10 | 80 | 88 | 13528 | 5.76477272727272 | 1 | 0.813525488435086 | 77.8650979974481
GOTERM_BP_FAT | GO:0007507~heart development | 4 | 3.77358490566037 | 0.130923055063469 | ACTC1, MYH7, TPM1, MYH10 | 80 | 215 | 13528 | 3.1460465116279 | 1 | 0.871429269497148 | 88.4141294281848
SP_PIR_KEYWORDS | calmodulin-binding | 3 | 2.83018867924528 | 0.139643850687971 | [NAME], [NAME], MYH10 | 106 | 120 | 19235 | 4.53655660377358 | 0.999999999999993 | 0.651062319449293 | 85.1976231701873
GOTERM_BP_FAT | GO:0042692~muscle cell differentiation | 3 | 2.83018867924528 | 0.157330489902774 | ACTC1, TPM1, MYH10 | 80 | 121 | 13528 | 4.19256198347107 | 1 | 0.899119423241655 | 92.7874499153736
GOTERM_BP_FAT | GO:0032989~cellular component morphogenesis | 5 | 4.71698113207547 | 0.201860667373556 | ACTB, S100A6, ACTC1, TPM1, MYH10 | 80 | 397 | 13528 | 2.12972292191435 | 1 | 0.933174139078619 | 96.867292542735
GOTERM_MF_FAT | GO:0005516~calmodulin binding | 3 | 2.83018867924528 | 0.217404386942179 | [NAME], [NAME], MYH10 | 82 | 140 | 12983 | 3.3927700348432 | 1 | 0.936136436737284 | 95.392899902217
GOTERM_CC_FAT | GO:0044463~cell projection part | 3 | 2.83018867924528 | 0.38743240627645 | [NAME], TPM1, MYH10 | 74 | 234 | 12782 | 2.21448371448371 | 1 | 0.880041284128105 | 99.8091013148167
Annotation Cluster 7 | Enrichment Score: 1.8236142577076553
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0030529~ribonucleoprotein complex | 11 | 10.377358490566 | 0.000654543728346863 | PABPN1, ACTB, RPL36A, LOC100291837, RPL18A, NPM1, U2AF1, RBM5, NOP56, RPS21, SF3B4 | 74 | 515 | 12782 | 3.68937286801364 | 0.136982714035596 | 0.0146240700018918 | 0.832992198318383
SMART | SM00360:RRM | 7 | 6.60377358490566 | 0.000993645639204129 | PABPN1, [NAME], TRA2B, U2AF1, RBM5, CPNE1, SF3B4 | 51 | 211 | 9079 | 5.90586376730787 | 0.0550903448181689 | 0.0550903448181689 | 0.980572234907239
INTERPRO | IPR000504:RNA recognition motif, RNP-1 | 7 | 6.60377358490566 | 0.00124067814007426 | PABPN1, [NAME], TRA2B, U2AF1, RBM5, CPNE1, SF3B4 | 95 | 211 | 16659 | 5.81756048889997 | 0.253037561553878 | 0.135730112496032 | 1.58436721282224
INTERPRO | IPR012677:Nucleotide-binding, alpha-beta plait | 7 | 6.60377358490566 | 0.0013020787374246 | PABPN1, [NAME], TRA2B, U2AF1, RBM5, CPNE1, SF3B4 | 95 | 213 | 16659 | 5.76293550778354 | 0.263751724983676 | 0.0970270023832072 | 1.66217229547993
GOTERM_BP_FAT | GO:0000375~[NAME] splicing, via transesterification reactions | 6 | 5.66037735849056 | 0.00199390930725391 | PABPN1, [NAME], TRA2B, U2AF1, RBM5, SF3B4 | 80 | 153 | 13528 | 6.6313725490196 | 0.799050858793785 | 0.135740432682308 | 3.01920417669064
GOTERM_BP_FAT | GO:0000377~RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | 6 | 5.66037735849056 | 0.00199390930725391 | PABPN1, [NAME], TRA2B, U2AF1, RBM5, SF3B4 | 80 | 153 | 13528 | 6.6313725490196 | 0.799050858793785 | 0.135740432682308 | 3.01920417669064
GOTERM_BP_FAT | GO:0000398~nuclear mRNA splicing, via spliceosome | 6 | 5.66037735849056 | 0.00199390930725391 | PABPN1, [NAME], TRA2B, U2AF1, RBM5, SF3B4 | 80 | 153 | 13528 | 6.6313725490196 | 0.799050858793785 | 0.135740432682308 | 3.01920417669064
GOTERM_MF_FAT | GO:0003723~RNA binding | 12 | 11.3207547169811 | 0.0048353432235965 | PABPN1, RPL36A, RPL18A, TRA2B, NPM1, U2AF1, RBM5, CPNE1, SLC4A1AP, LGTN, NOP56, SF3B4 | 82 | 718 | 12983 | 2.64617161491949 | 0.624354126829905 | 0.278461447724399 | 5.90375074333235
UP_SEQ_FEATURE | domain:RRM 1 | 4 | 3.77358490566037 | 0.0182046292066518 | RPL36A, RBM5, CPNE1, SF3B4 | 106 | 101 | 19113 | 7.1410424061274 | 0.998529557933966 | 0.886285466829068 | 22.260361032144
UP_SEQ_FEATURE | domain:RRM 2 | 4 | 3.77358490566037 | 0.0182046292066518 | RPL36A, RBM5, CPNE1, SF3B4 | 106 | 101 | 19113 | 7.1410424061274 | 0.998529557933966 | 0.886285466829068 | 22.260361032144
GOTERM_BP_FAT | GO:0008380~RNA splicing | 6 | 5.66037735849056 | 0.0251695840119054 | PABPN1, [NAME], TRA2B, U2AF1, RBM5, SF3B4 | 80 | 284 | 13528 | 3.5725352112676 | 0.999999998744047 | 0.545375517571339 | 32.3995643364662
SP_PIR_KEYWORDS | rna-binding | 8 | 7.54716981132075 | 0.0285031321312761 | PABPN1, [NAME], TRA2B, NPM1, U2AF1, RBM5, CPNE1, SF3B4 | 106 | 540 | 19235 | 2.68832983927323 | 0.998117283914206 | 0.341858936151139 | 30.7388063065879
GOTERM_BP_FAT | GO:0006397~mRNA processing | 6 | 5.66037735849056 | 0.0395532711459932 | PABPN1, [NAME], TRA2B, U2AF1, RBM5, SF3B4 | 80 | 321 | 13528 | 3.1607476635514 | 0.999999999999991 | 0.648895754298522 | 46.1992957080874
GOTERM_BP_FAT | GO:0006396~RNA processing | 8 | 7.54716981132075 | 0.0403228344514193 | PABPN1, SRRT, [NAME], TRA2B, U2AF1, RBM5, NOP56, SF3B4 | 80 | 547 | 13528 | 2.47312614259597 | 0.999999999999995 | 0.644454914934958 | 46.857644606801
SP_PIR_KEYWORDS | [NAME] | 5 | 4.71698113207547 | 0.0541859585921942 | PABPN1, TRA2B, U2AF1, RBM5, SF3B4 | 106 | 260 | 19235 | 3.48965892597968 | 0.999994378537583 | 0.4707312168946 | 50.7163861595118
GOTERM_BP_FAT | GO:0016071~mRNA metabolic process | 6 | 5.66037735849056 | 0.0650781204508312 | PABPN1, [NAME], TRA2B, U2AF1, RBM5, SF3B4 | 80 | 370 | 13528 | 2.74216216216216 | 1 | 0.741426506995495 | 64.4281687490743
SP_PIR_KEYWORDS | [NAME] | 4 | 3.77358490566037 | 0.106477239382474 | TRA2B, U2AF1, RBM5, SF3B4 | 106 | 209 | 19235 | 3.47296199331949 | 0.999999999975457 | 0.60923111112807 | 76.0679671365332
UP_SEQ_FEATURE | domain:RRM | 3 | 2.83018867924528 | 0.139193980712251 | PABPN1, TRA2B, U2AF1 | 106 | 119 | 19113 | 4.54566354843824 | 1 | 0.995111923668277 | 87.181530344269
SP_PIR_KEYWORDS | Spliceosome | 3 | 2.83018867924528 | 0.139643850687971 | U2AF1, RBM5, SF3B4 | 106 | 120 | 19235 | 4.53655660377358 | 0.999999999999993 | 0.651062319449293 | 85.1976231701873
GOTERM_CC_FAT | GO:0005681~spliceosome | 3 | 2.83018867924528 | 0.174009829427558 | U2AF1, RBM5, SF3B4 | 74 | 132 | 12782 | 3.92567567567567 | 1 | 0.717792173879935 | 91.3040083317223
KEGG_PATHWAY | hsa03040:Spliceosome | 3 | 2.83018867924528 | 0.260873611017162 | TRA2B, U2AF1, SF3B4 | 41 | 126 | 5085 | 2.95296167247386 | 0.999999955511511 | 0.728055306405692 | 94.9454876659599
Annotation Cluster 8 | Enrichment Score: 1.7661426848729282
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | EF hand | 6 | 5.66037735849056 | 1.89475890047568e-05 | S100A6, CAPNS1, ENPP2, SPARCL1, ACTN1, S100A2 | 106 | 60 | 19235 | 18.1462264150943 | 0.00410322444281086 | 0.00102738831667525 | 0.0240631644909394
INTERPRO | IPR018249:EF-HAND 2 | 7 | 6.60377358490566 | 0.00136577951742373 | MYL6, S100A6, CAPNS1, CALML4, SPARCL1, ACTN1, S100A2 | 95 | 215 | 16659 | 5.70932680538555 | 0.274705547662062 | 0.0771553710888796 | 1.74283214369477
INTERPRO | IPR011992:EF-Hand type | 7 | 6.60377358490566 | 0.00218802485959305 | MYL6, S100A6, CAPNS1, CALML4, SPARCL1, ACTN1, S100A2 | 95 | 236 | 16659 | 5.20129348795718 | 0.402349527225372 | 0.082214459438708 | 2.7785217115514
SP_PIR_KEYWORDS | calcium binding | 5 | 4.71698113207547 | 0.00245009084541469 | S100A6, CAPNS1, ACTN1, ANXA4, S100A2 | 106 | 103 | 19235 | 8.80884777431764 | 0.412760243536073 | 0.0518401851618453 | 3.0677043714527
UP_SEQ_FEATURE | domain:EF-hand 2 | 6 | 5.66037735849056 | 0.00332142780011085 | MYL6, S100A6, CAPNS1, CALML4, ACTN1, S100A2 | 106 | 182 | 19113 | 5.94432925565001 | 0.693049681953758 | 0.693049681953758 | 4.45740544917688
UP_SEQ_FEATURE | domain:EF-hand 1 | 5 | 4.71698113207547 | 0.0180634589427062 | MYL6, S100A6, CALML4, ACTN1, S100A2 | 106 | 182 | 19113 | 4.95360771304167 | 0.998452556669707 | 0.960662443768164 | 22.1070192654628
INTERPRO | [NAME]:EF-HAND 1 | 5 | 4.71698113207547 | 0.0344362774499446 | S100A6, CAPNS1, SPARCL1, ACTN1, S100A2 | 95 | 217 | 16659 | 4.04050448702401 | 0.999734832072237 | 0.691628361889257 | 36.2888430344187
SMART | SM00054:EFh | 4 | 3.77358490566037 | 0.0438134686009082 | MYL6, CAPNS1, CALML4, ACTN1 | 51 | 143 | 9079 | 4.97956945015768 | 0.922208981734634 | 0.573116057579657 | 35.8591817204492
INTERPRO | IPR002048:Calcium-binding EF-hand | 4 | 3.77358490566037 | 0.0471798946994494 | MYL6, CAPNS1, CALML4, ACTN1 | 95 | 143 | 16659 | 4.90511593669488 | 0.999988316729047 | 0.758205979821824 | 46.2983809606505
UP_SEQ_FEATURE | domain:EF-hand 3 | 3 | 2.83018867924528 | 0.0944333622984902 | MYL6, CAPNS1, CALML4 | 106 | 94 | 19113 | 5.75461661983139 | 0.999999999999999 | 0.997174310072771 | 74.3216440741027
SP_PIR_KEYWORDS | duplication | 4 | 3.77358490566037 | 0.128846101066144 | CAPNS1, ACTN1, C4BPA, ANXA4 | 106 | 228 | 19235 | 3.1835484938762 | 0.999999999999899 | 0.631288797772164 | 82.6567955763771
INTERPRO | IPR018248:EF hand | 3 | 2.83018867924528 | 0.166896273203797 | MYL6, S100A6, ACTN1 | 95 | 130 | 16659 | 4.04672064777327 | 1 | 0.986309216108629 | 90.4536153975062
GOTERM_MF_FAT | GO:0005509~calcium ion binding | 8 | 7.54716981132075 | 0.349148613822055 | MYL6, S100A6, CAPNS1, CALML4, SPARCL1, ACTN1, ANXA4, S100A2 | 82 | 919 | 12983 | 1.37827437033891 | 1 | 0.959768354470125 | 99.5446145596678
SP_PIR_KEYWORDS | calcium | 6 | 5.66037735849056 | 0.447376524244207 | S100A6, CAPNS1, SPARCL1, ACTN1, ANXA4, S100A2 | 106 | 803 | 19235 | 1.35588242204939 | 1 | 0.946332880377317 | 99.9464786522533
Annotation Cluster 9 | Enrichment Score: 1.6837035834834626
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | [NAME]~response to inorganic substance | 7 | 6.60377358490566 | 0.00124812167850622 | ACTB, FOS, SRRT, [NAME], [NAME], MYH7, TPM1 | 80 | 205 | 13528 | 5.77414634146341 | 0.633631854754513 | 0.0955349897542926 | 1.9000412823718
GOTERM_BP_FAT | GO:0051592~response to calcium ion | 3 | 2.83018867924528 | 0.0409703166042976 | ACTB, [NAME], DUSP1 | 80 | 55 | 13528 | 9.22363636363636 | 0.999999999999997 | 0.639120128821051 | 47.4057129164674
GOTERM_BP_FAT | GO:0010038~response to metal ion | 3 | 2.83018867924528 | 0.173845319709206 | ACTB, [NAME], DUSP1 | 80 | 129 | 13528 | 3.93255813953488 | 1 | 0.919305928035319 | 94.6782457709594
Annotation Cluster 10 | Enrichment Score: 1.3018521765192332
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0000302~response to reactive oxygen species | 4 | 3.77358490566037 | 0.00957410729546034 | FOS, DUSP1, MYH7, TPM1 | 80 | 75 | 13528 | 9.01866666666666 | 0.999562602385061 | 0.320727831942198 | 13.7368513467772
UP_SEQ_FEATURE | cross-link:[NAME] lysine isopeptide ([NAME]) (interchain with G-Cter in ubiquitin) | 5 | 4.71698113207547 | 0.0241418434578826 | FOS, EIF3I, [NAME], TPM1, TUBA1B | 106 | 199 | 19113 | 4.53043519484213 | 0.999829282815517 | 0.885693925646321 | 28.4618001115391
SP_PIR_KEYWORDS | isopeptide bond | 6 | 5.66037735849056 | 0.0306478670414052 | FOS, NPM1, EIF3I, [NAME], TPM1, TUBA1B | 106 | 319 | 19235 | 3.41308333826225 | 0.998834530945685 | 0.344373805694405 | 32.6560073117196
GOTERM_BP_FAT | GO:0006979~response to oxidative stress | 4 | 3.77358490566037 | 0.0710261425996224 | FOS, DUSP1, MYH7, TPM1 | 80 | 164 | 13528 | 4.12439024390244 | 1 | 0.747803113514511 | 67.7499316599063
GOTERM_MF_FAT | GO:0046982~protein heterodimerization activity | 4 | 3.77358490566037 | 0.140522111450229 | FOS, CAPNS1, NPM1, MYH7 | 82 | 208 | 12983 | 3.04479362101313 | 0.999999999999948 | 0.88751339992299 | 85.0597725458824
SP_PIR_KEYWORDS | ubl conjugation | 6 | 5.66037735849056 | 0.218501825911644 | FOS, NPM1, EIF3I, [NAME], TPM1, TUBA1B | 106 | 588 | 19235 | 1.85165575664227 | 1 | 0.764475007021109 | 95.6343401002348
Annotation Cluster 11 | Enrichment Score: 1.2295352469640015
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0051270~regulation of cell motion | 5 | 4.71698113207547 | 0.0263345539520807 | [NAME], LAMA4, ENPP2, ACTN1, TPM1 | 80 | 193 | 13528 | 4.38082901554404 | 0.999999999519774 | 0.548281014990536 | 33.6298512325505
GOTERM_BP_FAT | GO:0030334~regulation of cell migration | 4 | 3.77358490566037 | 0.0762061061617624 | [NAME], LAMA4, ENPP2, TPM1 | 80 | 169 | 13528 | 4.00236686390532 | 1 | 0.757371641760202 | 70.4041984386451
GOTERM_BP_FAT | GO:0040012~regulation of locomotion | 4 | 3.77358490566037 | 0.102065395057308 | [NAME], LAMA4, ENPP2, TPM1 | 80 | 192 | 13528 | 3.52291666666666 | 1 | 0.810725865836485 | 80.8647413852126
Annotation Cluster 12 | Enrichment Score: 1.1960581036849407
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0006414~translational elongation | 4 | 3.77358490566037 | 0.0212182801043299 | RPL36A, LOC100291837, RPL18A, RPS21 | 80 | 101 | 13528 | 6.69702970297029 | 0.99999996753442 | 0.498285183710366 | 28.0660719062332
GOTERM_CC_FAT | GO:0005840~ribosome | 5 | 4.71698113207547 | 0.0344314127999891 | RPL36A, LOC100291837, RPL18A, NPM1, RPS21 | 74 | 215 | 12782 | 4.01697045883092 | 0.999623119299796 | 0.354659226254283 | 36.0856970133719
GOTERM_CC_FAT | GO:0033279~ribosomal subunit | 4 | 3.77358490566037 | 0.0367372591811803 | LOC100291837, RPL18A, NPM1, RPS21 | 74 | 128 | 12782 | 5.39780405405405 | 0.99977992462299 | 0.358046219530772 | 38.0084509271036
GOTERM_BP_FAT | GO:0006412~translation | 6 | 5.66037735849056 | 0.044153799584478 | RPL36A, LOC100291837, RPL18A, EIF3I, LGTN, RPS21 | 80 | 331 | 13528 | 3.06525679758308 | 0.999999999999999 | 0.645607306631797 | 50.0243885915649
GOTERM_CC_FAT | GO:0015935~small ribosomal subunit | 3 | 2.83018867924528 | 0.0502481497174939 | LOC100291837, NPM1, RPS21 | 74 | 63 | 12782 | 8.22522522522522 | 0.999990831814969 | 0.424415974944077 | 48.2440582919439
GOTERM_CC_FAT | GO:0044445~cytosolic part | 4 | 3.77358490566037 | 0.0561184999711085 | LOC100291837, RPL18A, RPS21, ENO1 | 74 | 152 | 12782 | 4.54551920341394 | 0.999997727877924 | 0.431634820217455 | 52.1854395919075
SP_PIR_KEYWORDS | ribosome | 3 | 2.83018867924528 | 0.060397246847419 | LOC100291837, RPL18A, RPS21 | 106 | 73 | 19235 | 7.45735332127164 | 0.999998654421932 | 0.491319083622306 | 54.672874515217
GOTERM_CC_FAT | GO:0022626~cytosolic ribosome | 3 | 2.83018867924528 | 0.0781282718057899 | LOC100291837, RPL18A, RPS21 | 74 | 81 | 12782 | 6.39739739739739 | 0.999999988757531 | 0.519122489311302 | 64.6287252918355
SP_PIR_KEYWORDS | ribosomal protein | 4 | 3.77358490566037 | 0.0837803443792873 | RPL36A, LOC100291837, RPL18A, RPS21 | 106 | 188 | 19235 | 3.86089923725411 | 0.999999994325675 | 0.561999578080173 | 67.0885541882596
SP_PIR_KEYWORDS | protein biosynthesis | 4 | 3.77358490566037 | 0.0837803443792873 | LOC100291837, RPL18A, EIF3I, RPS21 | 106 | 188 | 19235 | 3.86089923725411 | 0.999999994325675 | 0.561999578080173 | 67.0885541882596
GOTERM_MF_FAT | GO:0003735~structural constituent of ribosome | 4 | 3.77358490566037 | 0.0875853663718784 | RPL36A, LOC100291837, RPL18A, RPS21 | 82 | 168 | 12983 | 3.76974448315911 | 0.999999990904367 | 0.786251664824987 | 68.3598829495377
KEGG_PATHWAY | hsa03010:Ribosome | 3 | 2.83018867924528 | 0.148973743921595 | RPL36A, RPL18A, RPS21 | 41 | 87 | 5085 | 4.2767031118587 | 0.999880654590688 | 0.594789610697867 | 79.6656408150379
SP_PIR_KEYWORDS | ribonucleoprotein | 4 | 3.77358490566037 | 0.195716635941596 | RPL36A, LOC100291837, RPL18A, RPS21 | 106 | 279 | 19235 | 2.60160952187732 | 1 | 0.750949510099692 | 93.7110828989654
Annotation Cluster 13 | Enrichment Score: 1.1780066664943314
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0046907~intracellular transport | 14 | 13.2075471698113 | 0.000101363661791807 | PABPN1, [NAME], ACTC1, SEC31A, [NAME], TPM1, NPM1, YWHAQ, RHOB, LGTN, KDELR1, COG1, SEC61G, MYH10 | 80 | 657 | 13528 | 3.60334855403348 | 0.0782677646039453 | 0.0161679751440976 | 0.155582273331256
GOTERM_BP_FAT | GO:0016192~vesicle-mediated transport | 8 | 7.54716981132075 | 0.0507905826658026 | SEC31A, [NAME], DENND1A, RHOB, VPS33B, KDELR1, COG1, MYH10 | 80 | 576 | 13528 | 2.34861111111111 | 1 | 0.677831399323689 | 55.0966459599042
GOTERM_BP_FAT | GO:0008104~protein localization | 10 | 9.43396226415094 | 0.0709608850095016 | SEC31A, NPM1, YWHAQ, RHOB, TMSB10, LGTN, VPS33B, KDELR1, COG1, SEC61G | 80 | 882 | 13528 | 1.9172335600907 | 1 | 0.755612259826956 | 67.7151162821575
GOTERM_BP_FAT | GO:0015031~protein transport | 9 | 8.49056603773585 | 0.0759972484435008 | SEC31A, NPM1, YWHAQ, RHOB, LGTN, VPS33B, KDELR1, COG1, SEC61G | 80 | 762 | 13528 | 1.99724409448818 | 1 | 0.764084256477879 | 70.3012536053592
GOTERM_BP_FAT | GO:0045184~establishment of protein localization | 9 | 8.49056603773585 | 0.0791996382695684 | SEC31A, NPM1, YWHAQ, RHOB, LGTN, VPS33B, KDELR1, COG1, SEC61G | 80 | 769 | 13528 | 1.97906371911573 | 1 | 0.763585051857407 | 71.8435157848878
SP_PIR_KEYWORDS | protein transport | 6 | 5.66037735849056 | 0.126312325426839 | SEC31A, RHOB, VPS33B, KDELR1, COG1, SEC61G | 106 | 485 | 19235 | 2.2448939894962 | 0.999999999999811 | 0.635931866389145 | 82.0050868189668
GOTERM_BP_FAT | GO:0006886~intracellular protein transport | 5 | 4.71698113207547 | 0.174770146046912 | NPM1, YWHAQ, LGTN, KDELR1, SEC61G | 80 | 374 | 13528 | 2.26069518716577 | 1 | 0.917174277619985 | 94.7690195053819
GOTERM_BP_FAT | GO:0034613~cellular protein localization | 5 | 4.71698113207547 | 0.218945408470991 | NPM1, YWHAQ, LGTN, KDELR1, SEC61G | 80 | 411 | 13528 | 2.05717761557177 | 1 | 0.943829939742011 | 97.7531397279586
GOTERM_BP_FAT | [NAME]~cellular macromolecule localization | 5 | 4.71698113207547 | 0.222658369466442 | NPM1, YWHAQ, LGTN, KDELR1, SEC61G | 80 | 414 | 13528 | 2.04227053140096 | 1 | 0.944588507634167 | 97.911719073035
SP_PIR_KEYWORDS | transport | 9 | 8.49056603773585 | 0.701196779626393 | SEC31A, ATP1B3, PITPNB, NDUFC2, RHOB, VPS33B, KDELR1, COG1, SEC61G | 106 | 1670 | 19235 | 0.977940345723647 | 1 | 0.995249862155922 | 99.9999782864863
Annotation Cluster 14 | Enrichment Score: 1.1351082998620716
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | [NAME]nucleolus | 11 | 10.377358490566 | 0.00608656737324001 | PABPN1, C19ORF33, FOS, RPL36A, NPM1, RBM5, ACTN1, MYH7, NOP56, ABL1, INO80B | 74 | 698 | 12782 | 2.72210175791837 | 0.746821968761137 | 0.108162968385891 | 7.50319358083849
GOTERM_CC_FAT | GO:0031981~nuclear lumen | 15 | 14.1509433962264 | 0.0333091615102861 | ACTB, PABPN1, RPL36A, RBM5, ACTN1, [NAME], C19ORF33, FOS, SRRT, ERCC5, NPM1, U2AF1, NOP56, ABL1, INO80B | 74 | 1450 | 12782 | 1.78685927306616 | 0.999510547430831 | 0.361329149757943 | 35.1301447906254
GOTERM_CC_FAT | GO:0070013~intracellular organelle lumen | 15 | 14.1509433962264 | 0.130259373526849 | ACTB, PABPN1, RPL36A, RBM5, ACTN1, [NAME], C19ORF33, FOS, SRRT, ERCC5, NPM1, U2AF1, NOP56, ABL1, INO80B | 74 | 1779 | 12782 | 1.45640581559637 | 0.999999999999976 | 0.661352312916775 | 83.1857067317579
GOTERM_CC_FAT | GO:0043233~organelle lumen | 15 | 14.1509433962264 | 0.148602217226497 | ACTB, PABPN1, RPL36A, RBM5, ACTN1, [NAME], C19ORF33, FOS, SRRT, ERCC5, NPM1, U2AF1, NOP56, ABL1, INO80B | 74 | 1820 | 12782 | 1.42359667359667 | 0.999999999999999 | 0.677340657117349 | 87.1940013380602
GOTERM_CC_FAT | GO:0031974~membrane-enclosed lumen | 15 | 14.1509433962264 | 0.165848817840869 | ACTB, PABPN1, RPL36A, RBM5, ACTN1, [NAME], C19ORF33, FOS, SRRT, ERCC5, NPM1, U2AF1, NOP56, ABL1, INO80B | 74 | 1856 | 12782 | 1.39598380708294 | 1 | 0.709575988328941 | 90.1401850601436
GOTERM_CC_FAT | GO:0005654~nucleoplasm | 8 | 7.54716981132075 | 0.237611475982339 | PABPN1, ACTB, FOS, SRRT, [NAME], ERCC5, NPM1, U2AF1 | 74 | 882 | 12782 | 1.56670956670956 | 1 | 0.782608794455333 | 96.8756962203478
Annotation Cluster 15 | Enrichment Score: 0.9849991300985306
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0006006~glucose metabolic process | 4 | 3.77358490566037 | 0.0602249625812336 | [NAME], PGM5, AKR1A1, ENO1 | 80 | 153 | 13528 | 4.42091503267973 | 1 | 0.722107116101057 | 61.4836924119265
GOTERM_BP_FAT | GO:0019318~hexose metabolic process | 4 | 3.77358490566037 | 0.102065395057308 | [NAME], PGM5, AKR1A1, ENO1 | 80 | 192 | 13528 | 3.52291666666666 | 1 | 0.810725865836485 | 80.8647413852126
GOTERM_BP_FAT | GO:0016052~carbohydrate catabolic process | 3 | 2.83018867924528 | 0.133203298424821 | [NAME], AKR1A1, ENO1 | 80 | 109 | 13528 | 4.65412844036697 | 1 | 0.871569229011513 | 88.872358432673
GOTERM_BP_FAT | GO:0005996~monosaccharide metabolic process | 4 | 3.77358490566037 | 0.140227580504563 | [NAME], PGM5, AKR1A1, ENO1 | 80 | 222 | 13528 | 3.04684684684684 | 1 | 0.87240422421594 | 90.1797048852223
Annotation Cluster 16 | Enrichment Score: 0.9237939227992833
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0046983~protein dimerization activity | 8 | 7.54716981132075 | 0.0520478937327382 | FOS, S100A6, ERCC5, CAPNS1, NPM1, RUNX1T1, [NAME], NFE2L2 | 82 | 542 | 12983 | 2.33696336963369 | 0.999979542527961 | 0.698710808632811 | 48.882750530426
GOTERM_MF_FAT | GO:0042803~protein homodimerization activity | 5 | 4.71698113207547 | 0.155483541993405 | S100A6, ERCC5, NPM1, RUNX1T1, MYH7 | 82 | 334 | 12983 | 2.37019862713597 | 0.999999999999998 | 0.881579338113245 | 88.015772250114
GOTERM_MF_FAT | GO:0042802~identical protein binding | 7 | 6.60377358490566 | 0.209185051748026 | DPY30, S100A6, ERCC5, NPM1, RUNX1T1, CSNK2B, MYH7 | 82 | 640 | 12983 | 1.73172637195121 | 1 | 0.938497944538424 | 94.7471780740103
Annotation Cluster 17 | Enrichment Score: 0.7827792432929909
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0043025~cell soma | 4 | 3.77358490566037 | 0.0712512736818505 | [NAME], [NAME], DENND1A, MYH10 | 74 | 168 | 12782 | 4.11261261261261 | 0.999999940144782 | 0.49991259432221 | 61.1056620436437
GOTERM_CC_FAT | GO:0043005~neuron projection | 5 | 4.71698113207547 | 0.131465829033102 | ACTB, [NAME], VIM, DENND1A, MYH10 | 74 | 342 | 12782 | 2.52528844634107 | 0.999999999999983 | 0.652542394330245 | 83.4812572076124
GOTERM_CC_FAT | GO:0030425~dendrite | 3 | 2.83018867924528 | 0.238592063550438 | [NAME], DENND1A, MYH10 | 74 | 163 | 12782 | 3.17907478030177 | 1 | 0.775952869245446 | 96.9266471875776
GOTERM_CC_FAT | GO:0045202~synapse | 4 | 3.77358490566037 | 0.330842669858423 | [NAME], [NAME], DENND1A, MYH10 | 74 | 355 | 12782 | 1.94625047582794 | 1 | 0.835987450831701 | 99.4097312618911
Annotation Cluster 18 | Enrichment Score: 0.729990871973997
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0042981~regulation of apoptosis | 9 | 8.49056603773585 | 0.0964245597010893 | [NAME], ERCC5, DUSP1, BTG2, NPM1, RBM5, ACTN1, ABL1, ANXA4 | 80 | 804 | 13528 | 1.89291044776119 | 1 | 0.810566413546589 | 78.9326784401669
GOTERM_BP_FAT | GO:0043067~regulation of programmed cell death | 9 | 8.49056603773585 | 0.100644643793459 | [NAME], ERCC5, DUSP1, BTG2, NPM1, RBM5, ACTN1, ABL1, ANXA4 | 80 | 812 | 13528 | 1.87426108374384 | 1 | 0.818358234749647 | 80.3943686765564
GOTERM_BP_FAT | GO:0010941~regulation of cell death | 9 | 8.49056603773585 | 0.102254154698638 | [NAME], ERCC5, DUSP1, BTG2, NPM1, RBM5, ACTN1, ABL1, ANXA4 | 80 | 815 | 13528 | 1.86736196319018 | 1 | 0.80530895487628 | 80.9264345793957
GOTERM_BP_FAT | [NAME]negative regulation of apoptosis | 4 | 3.77358490566037 | 0.341783984106084 | ERCC5, BTG2, NPM1, ANXA4 | 80 | 354 | 13528 | 1.91073446327683 | 1 | 0.981738916201975 | 99.8377733279426
GOTERM_BP_FAT | GO:0043069~negative regulation of programmed cell death | 4 | 3.77358490566037 | 0.34980708859986 | ERCC5, BTG2, NPM1, ANXA4 | 80 | 359 | 13528 | 1.88412256267409 | 1 | 0.981282306309886 | 99.865627284114
GOTERM_BP_FAT | GO:0060548~negative regulation of cell death | 4 | 3.77358490566037 | 0.35141084464307 | ERCC5, BTG2, NPM1, ANXA4 | 80 | 360 | 13528 | 1.87888888888888 | 1 | 0.979983458331674 | 99.8706290807383
Annotation Cluster 19 | Enrichment Score: 0.687357308159366
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0009991~response to extracellular stimulus | 4 | 3.77358490566037 | 0.137546190823344 | FOS, DUSP1, GNAI2, CSNK2B | 80 | 220 | 13528 | 3.07454545454545 | 1 | 0.871422242592072 | 89.6985932204995
GOTERM_BP_FAT | GO:0007584~response to nutrient | 3 | 2.83018867924528 | 0.196981163240807 | DUSP1, GNAI2, CSNK2B | 80 | 140 | 13528 | 3.62357142857142 | 1 | 0.933697393314385 | 96.5598426615037
GOTERM_BP_FAT | GO:0031667~response to nutrient levels | 3 | 2.83018867924528 | 0.319929885159036 | DUSP1, GNAI2, CSNK2B | 80 | 197 | 13528 | 2.57512690355329 | 1 | 0.97924299978575 | 99.732077642524
Annotation Cluster 20 | Enrichment Score: 0.6858549708722592
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0000166~nucleotide binding | 23 | 21.6981132075471 | 0.0173525354189288 | ACTB, PABPN1, RPL36A, ACTC1, ABCF3, GNAI2, [NAME], TRA2B, RBM5, UBE2F, [NAME], [NAME], SF3B4, ACTG2, DHRS3, UBA1, CPNE1, U2AF1, RHOB, ABL1, TUBA1B, TUBA1C, MYH10 | 82 | 2245 | 12983 | 1.62208159052637 | 0.970869827187532 | 0.445301263239601 | 19.7290735839078
KEGG_PATHWAY | hsa05416:Viral myocarditis | 4 | 3.77358490566037 | 0.0178181832339587 | ACTB, [NAME], [NAME], MYH10 | 41 | 71 | 5085 | 6.98728959120577 | 0.634619113680652 | 0.285094549272286 | 16.2663950352914
SP_PIR_KEYWORDS | nucleotide-binding | 15 | 14.1509433962264 | 0.0744970202311307 | ACTB, ACTC1, ABCF3, GNAI2, [NAME], UBE2F, [NAME], [NAME], ACTG2, UBA1, RHOB, ABL1, TUBA1B, TUBA1C, MYH10 | 106 | 1686 | 19235 | 1.61443295507956 | 0.99999994941902 | 0.534024528883742 | 62.5927443031915
SP_PIR_KEYWORDS | atp-binding | 11 | 10.377358490566 | 0.186996454576084 | ACTB, ACTG2, ABCF3, ACTC1, ACTA2, UBA1, UBE2F, [NAME], [NAME], ABL1, MYH10 | 106 | 1326 | 19235 | 1.50534306610888 | 1 | 0.74367576021761 | 92.7879225802686
GOTERM_MF_FAT | GO:0032553~ribonucleotide binding | 15 | 14.1509433962264 | 0.24956725299749 | ACTB, ACTC1, ABCF3, GNAI2, [NAME], UBE2F, [NAME], [NAME], ACTG2, UBA1, RHOB, ABL1, TUBA1B, TUBA1C, MYH10 | 82 | 1836 | 12983 | 1.29353977363303 | 1 | 0.919663643524461 | 97.2797047037904
GOTERM_MF_FAT | GO:0032555~purine ribonucleotide binding | 15 | 14.1509433962264 | 0.24956725299749 | ACTB, ACTC1, ABCF3, GNAI2, [NAME], UBE2F, [NAME], [NAME], ACTG2, UBA1, RHOB, ABL1, TUBA1B, TUBA1C, MYH10 | 82 | 1836 | 12983 | 1.29353977363303 | 1 | 0.919663643524461 | 97.2797047037904
GOTERM_MF_FAT | GO:0017076~purine nucleotide binding | 15 | 14.1509433962264 | 0.305216515571064 | ACTB, ACTC1, ABCF3, GNAI2, [NAME], UBE2F, [NAME], [NAME], ACTG2, UBA1, RHOB, ABL1, TUBA1B, TUBA1C, MYH10 | 82 | 1918 | 12983 | 1.23823723899387 | 1 | 0.953344822767281 | 98.9660070731047
GOTERM_MF_FAT | GO:0001883~purine nucleoside binding | 12 | 11.3207547169811 | 0.415189130810514 | ACTB, ACTG2, ABCF3, ACTC1, ACTA2, UBA1, RHOB, UBE2F, [NAME], [NAME], ABL1, MYH10 | 82 | 1601 | 12983 | 1.18672780731554 | 1 | 0.973007863136306 | 99.8811437326323
GOTERM_MF_FAT | GO:0001882~nucleoside binding | 12 | 11.3207547169811 | 0.4243894537862 | ACTB, ACTG2, ABCF3, ACTC1, ACTA2, UBA1, RHOB, UBE2F, [NAME], [NAME], ABL1, MYH10 | 82 | 1612 | 12983 | 1.17862978877927 | 1 | 0.972649332222464 | 99.9025988941465
GOTERM_MF_FAT | GO:0005524~ATP binding | 11 | 10.377358490566 | 0.442527084395126 | ACTB, ACTG2, ABCF3, ACTC1, ACTA2, UBA1, UBE2F, [NAME], [NAME], ABL1, MYH10 | 82 | 1477 | 12983 | 1.17916178146209 | 1 | 0.97203712126356 | 99.9348378296294
GOTERM_MF_FAT | GO:0032559~adenyl ribonucleotide binding | 11 | 10.377358490566 | 0.459999765632392 | ACTB, ACTG2, ABCF3, ACTC1, ACTA2, UBA1, UBE2F, [NAME], [NAME], ABL1, MYH10 | 82 | 1497 | 12983 | 1.1634081170471 | 1 | 0.974289813776378 | 99.9563111507475
GOTERM_MF_FAT | [NAME]~adenyl nucleotide binding | 11 | 10.377358490566 | 0.528990538648909 | ACTB, ACTG2, ABCF3, ACTC1, ACTA2, UBA1, UBE2F, [NAME], [NAME], ABL1, MYH10 | 82 | 1577 | 12983 | 1.10438931592867 | 1 | 0.985367014918338 | 99.9921460503425
UP_SEQ_FEATURE | nucleotide phosphate-binding region:ATP | 5 | 4.71698113207547 | 0.780813990962994 | UBA1, MYH7, [NAME], ABL1, MYH10 | 106 | 962 | 19113 | 0.937169026791668 | 1 | 0.999999999933074 | 99.9999999076523
Annotation Cluster 21 | Enrichment Score: 0.665566650836137
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | cell adhesion | 5 | 4.71698113207547 | 0.19939380911698 | VCAM1, LAMA4, PGM5, RHOB, [NAME] | 106 | 422 | 19235 | 2.15002682643297 | 1 | 0.748117814292907 | 94.0666692870177
GOTERM_BP_FAT | GO:0007155~cell adhesion | 7 | 6.60377358490566 | 0.22432514636222 | VCAM1, LAMA4, PGM5, CPXM2, RHOB, ACTN1, [NAME] | 80 | 700 | 13528 | 1.691 | 1 | 0.943670061301837 | 97.9794480602891
GOTERM_BP_FAT | GO:0022610~biological adhesion | 7 | 6.60377358490566 | 0.225273661390529 | VCAM1, LAMA4, PGM5, CPXM2, RHOB, ACTN1, [NAME] | 80 | 701 | 13528 | 1.68858773181169 | 1 | 0.94216959259469 | 98.0170681081978
Annotation Cluster 22 | Enrichment Score: 0.6334507525411577
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0007568~aging | 3 | 2.83018867924528 | 0.13517968180987 | FOS, ERCC5, NPM1 | 80 | 110 | 13528 | 4.61181818181818 | 1 | 0.871079197138073 | 89.2557610246356
GOTERM_CC_FAT | GO:0005654~nucleoplasm | 8 | 7.54716981132075 | 0.237611475982339 | PABPN1, ACTB, FOS, SRRT, [NAME], ERCC5, NPM1, U2AF1 | 74 | 882 | 12782 | 1.56670956670956 | 1 | 0.782608794455333 | 96.8756962203478
GOTERM_CC_FAT | GO:0044451~nucleoplasm part | 5 | 4.71698113207547 | 0.391623649709734 | ACTB, FOS, ERCC5, NPM1, U2AF1 | 74 | 555 | 12782 | 1.55612369125882 | 1 | 0.878730823466578 | 99.825131924039
Annotation Cluster 23 | Enrichment Score: 0.5717630611461975
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0003924~GTPase activity | 4 | 3.77358490566037 | 0.144859810525526 | GNAI2, RHOB, TUBA1B, TUBA1C | 82 | 211 | 12983 | 3.00150271644896 | 0.999999999999981 | 0.878446012144561 | 85.9792798080106
KEGG_PATHWAY | hsa04540:Gap junction | 3 | 2.83018867924528 | 0.154460990019587 | GNAI2, TUBA1B, TUBA1C | 41 | 89 | 5085 | 4.18059742395176 | 0.999916922321947 | 0.574358434538904 | 80.9238684793028
UP_SEQ_FEATURE | nucleotide phosphate-binding region:GTP | 4 | 3.77358490566037 | 0.220924137914898 | GNAI2, RHOB, TUBA1B, TUBA1C | 106 | 295 | 19113 | 2.44489926447073 | 1 | 0.999379748858545 | 96.7338783835932
SP_PIR_KEYWORDS | gtp-binding | 4 | 3.77358490566037 | 0.267648494244445 | GNAI2, RHOB, TUBA1B, TUBA1C | 106 | 329 | 19235 | 2.20622813557377 | 1 | 0.831159124718392 | 98.0867676344112
GOTERM_MF_FAT | GO:0005525~GTP binding | 4 | 3.77358490566037 | 0.410961764898145 | GNAI2, RHOB, TUBA1B, TUBA1C | 82 | 372 | 12983 | 1.70246525045895 | 1 | 0.974942918230594 | 99.8698953444617
GOTERM_MF_FAT | GO:0032561~guanyl ribonucleotide binding | 4 | 3.77358490566037 | 0.427701946631667 | GNAI2, RHOB, TUBA1B, TUBA1C | 82 | 382 | 12983 | 1.65789809730558 | 1 | 0.970488548459005 | 99.9094065806458
GOTERM_MF_FAT | GO:0019001~guanyl nucleotide binding | 4 | 3.77358490566037 | 0.427701946631667 | GNAI2, RHOB, TUBA1B, TUBA1C | 82 | 382 | 12983 | 1.65789809730558 | 1 | 0.970488548459005 | 99.9094065806458
Annotation Cluster 24 | Enrichment Score: 0.5466451513185303
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0009416~response to light stimulus | 3 | 2.83018867924528 | 0.192743653747579 | FOS, ERCC5, DUSP1 | 80 | 138 | 13528 | 3.67608695652173 | 1 | 0.93210597348606 | 96.2701839674608
GOTERM_BP_FAT | GO:0009314~response to radiation | 3 | 2.83018867924528 | 0.326372256853442 | FOS, ERCC5, DUSP1 | 80 | 200 | 13528 | 2.5365 | 1 | 0.980188868366338 | 99.7685194286295
GOTERM_BP_FAT | GO:0009628~response to abiotic stimulus | 4 | 3.77358490566037 | 0.364226234523708 | FOS, ERCC5, DUSP1, BTG2 | 80 | 368 | 13528 | 1.83804347826086 | 1 | 0.980069450176994 | 99.9047840932868
Annotation Cluster 25 | Enrichment Score: 0.5247377831032218
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | [NAME]~double-stranded DNA binding | 3 | 2.83018867924528 | 0.122697645350327 | KLF6, FOS, ERCC5 | 82 | 97 | 12983 | 4.89678149358813 | 0.999999999996717 | 0.869194047739462 | 80.6681078646245
GOTERM_MF_FAT | GO:0043566~structure-specific DNA binding | 3 | 2.83018867924528 | 0.228892580890111 | KLF6, FOS, ERCC5 | 82 | 145 | 12983 | 3.27577796467619 | 1 | 0.927579702476021 | 96.1735436243935
SP_PIR_KEYWORDS | dna-binding | 7 | 6.60377358490566 | 0.94911471386301 | HMGN1, KLF6, FOS, ERCC5, RUNX1T1, NFE2L2, ENO1 | 106 | 1868 | 19235 | 0.67999777786756 | 1 | 0.999982505963308 | 100
Annotation Cluster 26 | Enrichment Score: 0.5212585738039377
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0006928~cell motion | 7 | 6.60377358490566 | 0.0589082561182323 | VCAM1, ACTB, ENPP2, VIM, TPM1, MYH10, S100A2 | 80 | 475 | 13528 | 2.49199999999999 | 1 | 0.723237109751476 | 60.646398752964
GOTERM_BP_FAT | GO:0016477~cell migration | 3 | 2.83018867924528 | 0.481453162396114 | VCAM1, MYH10, S100A2 | 80 | 276 | 13528 | 1.83804347826086 | 1 | 0.991770764502981 | 99.9958397758291
GOTERM_BP_FAT | GO:0051674~localization of cell | 3 | 2.83018867924528 | 0.5384157398032 | VCAM1, MYH10, S100A2 | 80 | 307 | 13528 | 1.65244299674267 | 1 | 0.995713666705233 | 99.9993035921101
GOTERM_BP_FAT | GO:0048870~cell motility | 3 | 2.83018867924528 | 0.5384157398032 | VCAM1, MYH10, S100A2 | 80 | 307 | 13528 | 1.65244299674267 | 1 | 0.995713666705233 | 99.9993035921101
Annotation Cluster 27 | Enrichment Score: 0.4883775419200352
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0015630~[NAME] | 6 | 5.66037735849056 | 0.204131582413335 | PBXIP1, NPM1, [NAME], TUBA1B, TUBA1C, MYH10 | 74 | 549 | 12782 | 1.88775660906808 | 1 | 0.7599741902708 | 94.5898977252692
SP_PIR_KEYWORDS | microtubule | 3 | 2.83018867924528 | 0.360099252801074 | PBXIP1, TUBA1B, TUBA1C | 106 | 231 | 19235 | 2.35665278118108 | 1 | 0.911251514856217 | 99.6553444666839
GOTERM_CC_FAT | GO:0005874~microtubule | 3 | 2.83018867924528 | 0.466159942828785 | PBXIP1, TUBA1B, TUBA1C | 74 | 274 | 12782 | 1.8912014203985 | 1 | 0.923287907441507 | 99.9670721976782
Annotation Cluster 28 | Enrichment Score: 0.46656618456905263
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | nadp | 3 | 2.83018867924528 | 0.209473896428871 | DHRS3, [NAME], AKR1A1 | 106 | 156 | 19235 | 3.48965892597968 | 1 | 0.757527980248657 | 94.948655999515
SP_PIR_KEYWORDS | oxidoreductase | 5 | 4.71698113207547 | 0.36819875960794 | DHRS3, [NAME], AKR1A1, NDUFC2, LOXL1 | 106 | 562 | 19235 | 1.61443295507956 | 1 | 0.911989258386637 | 99.7068296482384
GOTERM_BP_FAT | GO:0055114~oxidation reduction | 5 | 4.71698113207547 | 0.516522463965764 | DHRS3, [NAME], AKR1A1, NDUFC2, LOXL1 | 80 | 639 | 13528 | 1.32316118935837 | 1 | 0.994320325989128 | 99.9985809741104
Annotation Cluster 29 | Enrichment Score: 0.40592654737368167
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | [NAME]~protein kinase binding | 3 | 2.83018867924528 | 0.233500695119401 | ACTB, VIM, PRKCDBP | 82 | 147 | 12983 | 3.23120955699352 | 1 | 0.922533636146361 | 96.450916296613
GOTERM_MF_FAT | GO:0019900~kinase binding | 3 | 2.83018867924528 | 0.30751544132166 | ACTB, VIM, PRKCDBP | 82 | 179 | 12983 | 2.65356315574328 | 1 | 0.948653179358738 | 99.0081479870791
GOTERM_MF_FAT | GO:0019899~enzyme binding | 3 | 2.83018867924528 | 0.843461477166465 | ACTB, VIM, PRKCDBP | 82 | 523 | 12983 | 0.908198479690341 | 1 | 0.999654391140803 | 99.999999992256
Annotation Cluster 30 | Enrichment Score: 0.39792081374218763
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0032989~cellular component morphogenesis | 5 | 4.71698113207547 | 0.201860667373556 | ACTB, S100A6, ACTC1, TPM1, MYH10 | 80 | 397 | 13528 | 2.12972292191435 | 1 | 0.933174139078619 | 96.867292542735
GOTERM_BP_FAT | GO:0007409~axonogenesis | 3 | 2.83018867924528 | 0.311319146070163 | ACTB, S100A6, MYH10 | 80 | 193 | 13528 | 2.62849740932642 | 1 | 0.977536655179165 | 99.6749565599741
GOTERM_BP_FAT | GO:0048667~cell morphogenesis involved in neuron differentiation | 3 | 2.83018867924528 | 0.345603250998783 | ACTB, S100A6, MYH10 | 80 | 209 | 13528 | 2.42727272727272 | 1 | 0.981883521754274 | 99.8516448919635
GOTERM_BP_FAT | GO:0048812~neuron projection morphogenesis | 3 | 2.83018867924528 | 0.354097085201002 | ACTB, S100A6, MYH10 | 80 | 213 | 13528 | 2.38169014084507 | 1 | 0.979855304054761 | 99.8786189079357
GOTERM_BP_FAT | [NAME]~cell projection organization | 4 | 3.77358490566037 | 0.364226234523708 | ACTB, S100A6, TPM1, MYH10 | 80 | 368 | 13528 | 1.83804347826086 | 1 | 0.980069450176994 | 99.9047840932868
GOTERM_BP_FAT | GO:0000904~cell morphogenesis involved in differentiation | 3 | 2.83018867924528 | 0.418467387306237 | ACTB, S100A6, MYH10 | 80 | 244 | 13528 | 2.07909836065573 | 1 | 0.988290280421414 | 99.9757988680884
GOTERM_BP_FAT | GO:0048858~cell projection morphogenesis | 3 | 2.83018867924528 | 0.420493735004822 | ACTB, S100A6, MYH10 | 80 | 245 | 13528 | 2.07061224489795 | 1 | 0.98755521468494 | 99.9770622560102
GOTERM_BP_FAT | GO:0032990~cell part morphogenesis | 3 | 2.83018867924528 | 0.442547165389594 | ACTB, S100A6, MYH10 | 80 | 256 | 13528 | 1.98164062499999 | 1 | 0.989085757320165 | 99.9873604094266
GOTERM_BP_FAT | [NAME]neuron projection development | 3 | 2.83018867924528 | 0.442547165389594 | ACTB, S100A6, MYH10 | 80 | 256 | 13528 | 1.98164062499999 | 1 | 0.989085757320165 | 99.9873604094266
GOTERM_BP_FAT | GO:0030182~neuron differentiation | 4 | 3.77358490566037 | 0.473648093828185 | ACTB, S100A6, BTG2, MYH10 | 80 | 438 | 13528 | 1.54429223744292 | 1 | 0.991952441220302 | 99.9947666925641
GOTERM_BP_FAT | [NAME] development | 3 | 2.83018867924528 | 0.592637275138205 | ACTB, S100A6, MYH10 | 80 | 339 | 13528 | 1.49646017699115 | 1 | 0.997683055738871 | 99.9998978411657
GOTERM_BP_FAT | GO:0000902~cell morphogenesis | 3 | 2.83018867924528 | 0.619492814623193 | ACTB, S100A6, MYH10 | 80 | 356 | 13528 | 1.425 | 1 | 0.998371951707522 | 99.999964162794
Annotation Cluster 31 | Enrichment Score: 0.3930431984721074
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0005789~endoplasmic reticulum membrane | 4 | 3.77358490566037 | 0.198692039861954 | [NAME], SPCS2, KRTCAP2, SEC61G | 74 | 269 | 12782 | 2.56847181754245 | 1 | 0.759249089676751 | 94.0980225201809
GOTERM_CC_FAT | GO:0042175~nuclear envelope-endoplasmic reticulum network | 4 | 3.77358490566037 | 0.220909655565201 | [NAME], SPCS2, KRTCAP2, SEC61G | 74 | 284 | 12782 | 2.43281309478492 | 1 | 0.780852381530399 | 95.8791313888903
GOTERM_CC_FAT | GO:0031090~[NAME] membrane | 9 | 8.49056603773585 | 0.287139729844667 | [NAME], [NAME], NDUFC2, DENND1A, RHOB, SPCS2, KRTCAP2, VPS33B, SEC61G | 74 | 1096 | 12782 | 1.41840106529887 | 1 | 0.81591345184413 | 98.6754466947118
GOTERM_CC_FAT | GO:0012505~endomembrane system | 7 | 6.60377358490566 | 0.288019891674551 | [NAME], [NAME], SEC31A, DENND1A, SPCS2, KRTCAP2, SEC61G | 74 | 782 | 12782 | 1.54617405128914 | 1 | 0.810165386049395 | 98.6961885792355
GOTERM_CC_FAT | GO:0044432~endoplasmic reticulum part | 4 | 3.77358490566037 | 0.318267707126916 | [NAME], SPCS2, KRTCAP2, SEC61G | 74 | 347 | 12782 | 1.99112080380091 | 1 | 0.834016468958903 | 99.2512323540223
SP_PIR_KEYWORDS | endoplasmic reticulum | 5 | 4.71698113207547 | 0.549036651685492 | [NAME], [NAME], [NAME], KDELR1, SEC61G | 106 | 713 | 19235 | 1.27252639657043 | 1 | 0.976641286331139 | 99.995952779902
GOTERM_CC_FAT | GO:0005783~endoplasmic reticulum | 6 | 5.66037735849056 | 0.649527831397251 | [NAME], [NAME], [NAME], KRTCAP2, KDELR1, SEC61G | 74 | 960 | 12782 | 1.07956081081081 | 1 | 0.976353730879209 | 99.9998476799235
UP_SEQ_FEATURE | topological domain:Lumenal | 3 | 2.83018867924528 | 0.704422235511341 | [NAME], [NAME], KDELR1 | 106 | 444 | 19113 | 1.21831973482916 | 1 | 0.999999998873238 | 99.9999944380899
UP_SEQ_FEATURE | topological domain:Cytoplasmic | 8 | 7.54716981132075 | 0.999713467960966 | [NAME], VCAM1, ATP1B3, TSPAN6, SPCS2, KDELR1, SEC61G, PMEPA1 | 106 | 3374 | 19113 | 0.427531288096542 | 1 | 1 | 100
Annotation Cluster 32 | Enrichment Score: 0.3807446221838491
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | [NAME]cell fraction | 9 | 8.49056603773585 | 0.276189970918853 | ACTB, FOS, ACTC1, [NAME], GNAI2, YWHAQ, RHOB, SPCS2, KDELR1 | 74 | 1083 | 12782 | 1.43542711686756 | 1 | 0.808498918277974 | 98.3906700303818
GOTERM_CC_FAT | GO:0005624~membrane fraction | 6 | 5.66037735849056 | 0.494671100101628 | FOS, [NAME], GNAI2, RHOB, SPCS2, KDELR1 | 74 | 809 | 12782 | 1.28106103631443 | 1 | 0.9355825948772 | 99.98366817375
GOTERM_CC_FAT | GO:0005626~insoluble fraction | 6 | 5.66037735849056 | 0.527523353414212 | FOS, [NAME], GNAI2, RHOB, SPCS2, KDELR1 | 74 | 839 | 12782 | 1.23525432464645 | 1 | 0.945446789723029 | 99.993080546432
Annotation Cluster 33 | Enrichment Score: 0.3789364658922547
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
INTERPRO | IPR019782:WD40 repeat 2 | 3 | 2.83018867924528 | 0.365308004123449 | WSB1, [NAME], EIF3I | 95 | 226 | 16659 | 2.32775966464834 | 1 | 0.999939461983775 | 99.711539699761
UP_SEQ_FEATURE | repeat:WD 5 | 3 | 2.83018867924528 | 0.366954995391085 | WSB1, [NAME], EIF3I | 106 | 233 | 19113 | 2.32160498825815 | 1 | 0.999996218737965 | 99.8100950572392
INTERPRO | [NAME]:WD40 repeat, region | 3 | 2.83018867924528 | 0.389503162999544 | WSB1, [NAME], EIF3I | 95 | 238 | 16659 | 2.21039363113666 | 1 | 0.999936471743037 | 99.825039666684
INTERPRO | IPR019781:WD40 repeat, subgroup | 3 | 2.83018867924528 | 0.397480989859609 | WSB1, [NAME], EIF3I | 95 | 242 | 16659 | 2.17385819921705 | 1 | 0.999894670931315 | 99.8522765523604
UP_SEQ_FEATURE | repeat:WD 4 | 3 | 2.83018867924528 | 0.402083389298745 | WSB1, [NAME], EIF3I | 106 | 251 | 19113 | 2.15511538750657 | 1 | 0.999997831076371 | 99.9131600888425
UP_SEQ_FEATURE | repeat:WD 3 | 3 | 2.83018867924528 | 0.428774910775438 | WSB1, [NAME], EIF3I | 106 | 265 | 19113 | 2.04126023495906 | 1 | 0.999998244346437 | 99.9535601375403
SMART | SM00320:WD40 | 3 | 2.83018867924528 | 0.43311575774511 | WSB1, [NAME], EIF3I | 51 | 266 | 9079 | 2.00773993808049 | 0.999999999999991 | 0.99845176817908 | 99.6397649187924
INTERPRO | IPR001680:WD40 repeat | 3 | 2.83018867924528 | 0.444297312156986 | WSB1, [NAME], EIF3I | 95 | 266 | 16659 | 1.9777206173328 | 1 | 0.999947880641274 | 99.9478151450565
UP_SEQ_FEATURE | repeat:WD 2 | 3 | 2.83018867924528 | 0.44560653431228 | WSB1, [NAME], EIF3I | 106 | 274 | 19113 | 1.97421154111004 | 1 | 0.999997930029495 | 99.9691776198568
UP_SEQ_FEATURE | repeat:WD 1 | 3 | 2.83018867924528 | 0.44560653431228 | WSB1, [NAME], EIF3I | 106 | 274 | 19113 | 1.97421154111004 | 1 | 0.999997930029495 | 99.9691776198568
SP_PIR_KEYWORDS | wd repeat | 3 | 2.83018867924528 | 0.446066289937981 | WSB1, [NAME], EIF3I | 106 | 276 | 19235 | 1.97241591468416 | 1 | 0.949259261851552 | 99.9448443700717
INTERPRO | IPR019775:WD40 repeat, conserved site | 3 | 2.83018867924528 | 0.465090418454704 | WSB1, [NAME], EIF3I | 95 | 277 | 16659 | 1.89918297548926 | 1 | 0.999944657440134 | 99.9680491611007
Annotation Cluster 34 | Enrichment Score: 0.35207626362704963
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0010033~response to organic substance | 7 | 6.60377358490566 | 0.244522236993252 | FOS, SRRT, ACTC1, DUSP1, BTG2, CSNK2B, NFE2L2 | 80 | 721 | 13528 | 1.64174757281553 | 1 | 0.952477960435812 | 98.6526710180121
GOTERM_BP_FAT | GO:0009628~response to abiotic stimulus | 4 | 3.77358490566037 | 0.364226234523708 | FOS, ERCC5, DUSP1, BTG2 | 80 | 368 | 13528 | 1.83804347826086 | 1 | 0.980069450176994 | 99.9047840932868
GOTERM_BP_FAT | GO:0009725~response to hormone stimulus | 3 | 2.83018867924528 | 0.636146676903566 | FOS, DUSP1, BTG2 | 80 | 367 | 13528 | 1.38228882833787 | 1 | 0.998500735507338 | 99.9999819786458
GOTERM_BP_FAT | [NAME]~response to endogenous stimulus | 3 | 2.83018867924528 | 0.689363203925768 | FOS, DUSP1, BTG2 | 80 | 405 | 13528 | 1.25259259259259 | 1 | 0.999101501431882 | 99.9999984116112
Annotation Cluster 35 | Enrichment Score: 0.35125658194555165
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0044433~cytoplasmic vesicle part | 3 | 2.83018867924528 | 0.289467254952943 | SEC31A, DENND1A, ACTN1 | 74 | 187 | 12782 | 2.77106518282988 | 1 | 0.805240640323113 | 98.7296472366974
GOTERM_BP_FAT | [NAME]~membrane organization | 4 | 3.77358490566037 | 0.384971205830585 | SEC31A, DENND1A, VPS33B, MYH10 | 80 | 381 | 13528 | 1.7753280839895 | 1 | 0.983654852218258 | 99.9427975983962
GOTERM_CC_FAT | GO:0016023~cytoplasmic membrane-bounded vesicle | 5 | 4.71698113207547 | 0.385084345528413 | SEC31A, ATP1B3, DENND1A, ACTN1, VPS33B | 74 | 550 | 12782 | 1.57027027027027 | 1 | 0.882968197366929 | 99.7995390877185
GOTERM_CC_FAT | GO:0031988~membrane-bounded vesicle | 5 | 4.71698113207547 | 0.408585174419014 | SEC31A, ATP1B3, DENND1A, ACTN1, VPS33B | 74 | 568 | 12782 | 1.52050818424057 | 1 | 0.887914130959574 | 99.8781496226415
GOTERM_CC_FAT | GO:0031410~cytoplasmic vesicle | 5 | 4.71698113207547 | 0.502834173892361 | SEC31A, ATP1B3, DENND1A, ACTN1, VPS33B | 74 | 642 | 12782 | 1.34524711627515 | 1 | 0.936616138739424 | 99.9867359580147
GOTERM_CC_FAT | GO:0031982~vesicle | 5 | 4.71698113207547 | 0.536914031092707 | SEC31A, ATP1B3, DENND1A, ACTN1, VPS33B | 74 | 670 | 12782 | 1.28902783380395 | 1 | 0.946913906994207 | 99.9946459007359
GOTERM_CC_FAT | GO:0044459~plasma membrane part | 12 | 11.3207547169811 | 0.734527785699925 | VCAM1, PGM5, [NAME], AKR1A1, ATP1B3, ENPP2, DENND1A, ACTN1, [NAME], VPS33B, TPM1, COG1 | 74 | 2203 | 12782 | 0.940879145146053 | 1 | 0.989855751823134 | 99.9999956187193
Annotation Cluster 36 | Enrichment Score: 0.3415229428394318
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0033554~cellular response to stress | 6 | 5.66037735849056 | 0.235205505552217 | FOS, ERCC5, BTG2, NFE2L2, ABL1, TPM1 | 80 | 566 | 13528 | 1.79257950530035 | 1 | 0.947832862771026 | 98.3735659253663
GOTERM_BP_FAT | GO:0006281~DNA repair | 3 | 2.83018867924528 | 0.496555231139228 | ERCC5, BTG2, ABL1 | 80 | 284 | 13528 | 1.7862676056338 | 1 | 0.993063112915761 | 99.9973578823706
GOTERM_BP_FAT | GO:0006259~DNA metabolic process | 4 | 3.77358490566037 | 0.571398069151576 | FOS, ERCC5, BTG2, ABL1 | 80 | 506 | 13528 | 1.33675889328063 | 1 | 0.997038229448111 | 99.9997769938879
GOTERM_BP_FAT | GO:0006974~response to DNA damage stimulus | 3 | 2.83018867924528 | 0.644992129842597 | ERCC5, BTG2, ABL1 | 80 | 373 | 13528 | 1.36005361930294 | 1 | 0.998578693667907 | 99.9999876515304
Annotation Cluster 37 | Enrichment Score: 0.32413185753595775
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0008219~cell death | 6 | 5.66037735849056 | 0.411042884541109 | [NAME], PDCL3, ACTC1, UBA1, RBM5, RHOB | 80 | 719 | 13528 | 1.41112656467315 | 1 | 0.98812999882698 | 99.9705921266764
GOTERM_BP_FAT | GO:0016265~death | 6 | 5.66037735849056 | 0.416896646946804 | [NAME], PDCL3, ACTC1, UBA1, RBM5, RHOB | 80 | 724 | 13528 | 1.40138121546961 | 1 | 0.988562148183218 | 99.974775099093
GOTERM_BP_FAT | [NAME]~apoptosis | 5 | 4.71698113207547 | 0.469537448914732 | [NAME], PDCL3, ACTC1, RBM5, RHOB | 80 | 602 | 13528 | 1.40448504983388 | 1 | 0.992208125855073 | 99.9941024615781
GOTERM_BP_FAT | GO:0012501~programmed cell death | 5 | 4.71698113207547 | 0.481119271356492 | [NAME], PDCL3, ACTC1, RBM5, RHOB | 80 | 611 | 13528 | 1.38379705400982 | 1 | 0.992087816354552 | 99.9957984390788
SP_PIR_KEYWORDS | Apoptosis | 3 | 2.83018867924528 | 0.618731442562149 | PDCL3, RBM5, RHOB | 106 | 381 | 19235 | 1.42883672559797 | 1 | 0.987211632556843 | 99.9995201511505
Annotation Cluster 38 | Enrichment Score: 0.3095149368495359
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0015630~[NAME] | 6 | 5.66037735849056 | 0.204131582413335 | PBXIP1, NPM1, [NAME], TUBA1B, TUBA1C, MYH10 | 74 | 549 | 12782 | 1.88775660906808 | 1 | 0.7599741902708 | 94.5898977252692
GOTERM_BP_FAT | GO:0034622~cellular macromolecular complex assembly | 4 | 3.77358490566037 | 0.284088142025769 | NPM1, RBM5, TUBA1B, TUBA1C | 80 | 318 | 13528 | 2.12704402515723 | 1 | 0.970854810676894 | 99.4103026943363
GOTERM_BP_FAT | GO:0034621~cellular macromolecular complex subunit organization | 4 | 3.77358490566037 | 0.346598633943282 | NPM1, RBM5, TUBA1B, TUBA1C | 80 | 357 | 13528 | 1.89467787114845 | 1 | 0.981286791205863 | 99.8550734270287
GOTERM_BP_FAT | GO:0007017~microtubule-based process | 3 | 2.83018867924528 | 0.436576538452461 | NPM1, TUBA1B, TUBA1C | 80 | 253 | 13528 | 2.00513833992094 | 1 | 0.988648297847297 | 99.9851132094202
GOTERM_BP_FAT | GO:0065003~macromolecular complex assembly | 4 | 3.77358490566037 | 0.752500282623436 | NPM1, RBM5, TUBA1B, TUBA1C | 80 | 665 | 13528 | 1.01714285714285 | 1 | 0.999670855822842 | 99.9999999515548
GOTERM_BP_FAT | GO:0043933~macromolecular complex subunit organization | 4 | 3.77358490566037 | 0.791211902290883 | NPM1, RBM5, TUBA1B, TUBA1C | 80 | 710 | 13528 | 0.952676056338028 | 1 | 0.999820641482337 | 99.9999999964468
GOTERM_BP_FAT | GO:0006461~protein complex assembly | 3 | 2.83018867924528 | 0.799678166710307 | NPM1, TUBA1B, TUBA1C | 80 | 505 | 13528 | 1.00455445544554 | 1 | 0.999848336442709 | 99.9999999981186
GOTERM_BP_FAT | GO:0070271~protein complex biogenesis | 3 | 2.83018867924528 | 0.799678166710307 | NPM1, TUBA1B, TUBA1C | 80 | 505 | 13528 | 1.00455445544554 | 1 | 0.999848336442709 | 99.9999999981186
Annotation Cluster 39 | Enrichment Score: 0.28868685445491044
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0016564~transcription repressor activity | 4 | 3.77358490566037 | 0.315454599476291 | PBXIP1, RUNX1T1, SCMH1, ENO1 | 82 | 316 | 12983 | 2.00416795307193 | 1 | 0.947373783415146 | 99.1418236031145
GOTERM_BP_FAT | [NAME]negative regulation of gene expression | 5 | 4.71698113207547 | 0.339716710614507 | SRRT, PBXIP1, YWHAQ, SCMH1, ENO1 | 80 | 504 | 13528 | 1.67757936507936 | 1 | 0.982062038549608 | 99.8297682484687
GOTERM_BP_FAT | GO:0045934~negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 5 | 4.71698113207547 | 0.350411335487329 | PBXIP1, NPM1, YWHAQ, SCMH1, ENO1 | 80 | 512 | 13528 | 1.65136718749999 | 1 | 0.98058235147216 | 99.8675326640319
GOTERM_BP_FAT | [NAME]~negative regulation of nitrogen compound metabolic process | 5 | 4.71698113207547 | 0.359776293287917 | PBXIP1, NPM1, YWHAQ, SCMH1, ENO1 | 80 | 519 | 13528 | 1.6290944123314 | 1 | 0.98055047043838 | 99.8940166826273
GOTERM_MF_FAT | GO:0008134~transcription factor binding | 5 | 4.71698113207547 | 0.398601881891499 | PBXIP1, ENPP2, NPM1, CSNK2B, ENO1 | 82 | 513 | 12983 | 1.54317025626396 | 1 | 0.974484032592811 | 99.8311443704704
GOTERM_BP_FAT | GO:0010605~negative regulation of macromolecule metabolic process | 6 | 5.66037735849056 | 0.42858054022093 | SRRT, PBXIP1, NPM1, YWHAQ, SCMH1, ENO1 | 80 | 734 | 13528 | 1.38228882833787 | 1 | 0.988378404546136 | 99.9815155568926
GOTERM_BP_FAT | GO:0016481~negative regulation of transcription | 4 | 3.77358490566037 | 0.504938704065235 | PBXIP1, YWHAQ, SCMH1, ENO1 | 80 | 459 | 13528 | 1.47363834422657 | 1 | 0.9935718257999 | 99.9979585762582
GOTERM_BP_FAT | GO:0010558~negative regulation of macromolecule biosynthetic process | 4 | 3.77358490566037 | 0.624792943140115 | PBXIP1, YWHAQ, SCMH1, ENO1 | 80 | 547 | 13528 | 1.23656307129798 | 1 | 0.998435498136124 | 99.9999711090026
GOTERM_BP_FAT | GO:0051253~negative regulation of RNA metabolic process | 3 | 2.83018867924528 | 0.628647021223794 | NPM1, YWHAQ, ENO1 | 80 | 362 | 13528 | 1.40138121546961 | 1 | 0.998376120316807 | 99.9999753460477
GOTERM_BP_FAT | [NAME] regulation of cellular biosynthetic process | 4 | 3.77358490566037 | 0.641978165329325 | PBXIP1, YWHAQ, SCMH1, ENO1 | 80 | 561 | 13528 | 1.20570409982174 | 1 | 0.998575974226415 | 99.9999859392585
GOTERM_BP_FAT | GO:0009890~negative regulation of biosynthetic process | 4 | 3.77358490566037 | 0.656273954572373 | PBXIP1, YWHAQ, SCMH1, ENO1 | 80 | 573 | 13528 | 1.1804537521815 | 1 | 0.998778666137801 | 99.9999924806633
GOTERM_MF_FAT | GO:0003712~transcription cofactor activity | 3 | 2.83018867924528 | 0.66606689284138 | PBXIP1, NPM1, ENO1 | 82 | 363 | 12983 | 1.3085063495263 | 1 | 0.997063202039896 | 99.9998953262666
GOTERM_MF_FAT | GO:0030528~transcription regulator activity | 9 | 8.49056603773585 | 0.74107970044851 | HMGN1, KLF6, FOS, PBXIP1, NPM1, RUNX1T1, NFE2L2, SCMH1, ENO1 | 82 | 1512 | 12983 | 0.942436120789779 | 1 | 0.998494750853851 | 99.9999957079842
GOTERM_BP_FAT | GO:0045449~regulation of transcription | 11 | 10.377358490566 | 0.954504436409451 | KLF6, FOS, PBXIP1, BTG2, NPM1, RUNX1T1, YWHAQ, NFE2L2, ABL1, SCMH1, ENO1 | 80 | 2601 | 13528 | 0.71514801999231 | 1 | 0.999999836363104 | 100
Annotation Cluster 40 | Enrichment Score: 0.23471235014169908
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | ubl conjugation pathway | 5 | 4.71698113207547 | 0.302457498664112 | WSB1, UBA1, ZRANB1, UBE2F, PMEPA1 | 106 | 509 | 19235 | 1.78253697594246 | 1 | 0.86522442663161 | 98.9692581492881
GOTERM_BP_FAT | GO:0006508~proteolysis | 8 | 7.54716981132075 | 0.419571758494552 | WSB1, CAPNS1, UBA1, ZRANB1, CPXM2, UBE2F, [NAME], SPCS2 | 80 | 1054 | 13528 | 1.28349146110056 | 1 | 0.987939876852336 | 99.9764952676516
GOTERM_BP_FAT | GO:0044265~cellular macromolecule catabolic process | 5 | 4.71698113207547 | 0.617722102073005 | WSB1, ERCC5, UBA1, ZRANB1, UBE2F | 80 | 725 | 13528 | 1.16620689655172 | 1 | 0.998408009147717 | 99.9999615137927
GOTERM_BP_FAT | GO:0019941~modification-dependent protein catabolic process | 4 | 3.77358490566037 | 0.657447074323359 | WSB1, UBA1, ZRANB1, UBE2F | 80 | 574 | 13528 | 1.17839721254355 | 1 | 0.998740601355 | 99.9999928653368
GOTERM_BP_FAT | GO:0043632~modification-dependent macromolecule catabolic process | 4 | 3.77358490566037 | 0.657447074323359 | WSB1, UBA1, ZRANB1, UBE2F | 80 | 574 | 13528 | 1.17839721254355 | 1 | 0.998740601355 | 99.9999928653368
GOTERM_BP_FAT | GO:0009057~macromolecule catabolic process | 5 | 4.71698113207547 | 0.676287498593588 | WSB1, ERCC5, UBA1, ZRANB1, UBE2F | 80 | 781 | 13528 | 1.08258642765685 | 1 | 0.999014513911572 | 99.9999970077114
GOTERM_BP_FAT | GO:0051603~proteolysis involved in cellular protein catabolic process | 4 | 3.77358490566037 | 0.686962060244881 | WSB1, UBA1, ZRANB1, UBE2F | 80 | 600 | 13528 | 1.12733333333333 | 1 | 0.999107050628223 | 99.9999982121866
GOTERM_BP_FAT | GO:0044257~cellular protein catabolic process | 4 | 3.77358490566037 | 0.690245360845763 | WSB1, UBA1, ZRANB1, UBE2F | 80 | 603 | 13528 | 1.12172470978441 | 1 | 0.999069474354145 | 99.9999984795018
GOTERM_BP_FAT | GO:0030163~protein catabolic process | 4 | 3.77358490566037 | 0.710453898129738 | WSB1, UBA1, ZRANB1, UBE2F | 80 | 622 | 13528 | 1.08745980707395 | 1 | 0.999342642185991 | 99.9999994605718
Annotation Cluster 41 | Enrichment Score: 0.1752605847628421
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_CC_FAT | GO:0005578~proteinaceous extracellular matrix | 3 | 2.83018867924528 | 0.549084416724039 | LAMA4, SPARCL1, LOXL1 | 74 | 320 | 12782 | 1.61934121621621 | 1 | 0.949550465119534 | 99.9961900342801
GOTERM_CC_FAT | GO:0031012~extracellular matrix | 3 | 2.83018867924528 | 0.590308181232764 | LAMA4, SPARCL1, LOXL1 | 74 | 345 | 12782 | 1.50199764982373 | 1 | 0.960772104517101 | 99.9988806170604
GOTERM_CC_FAT | GO:0044421~extracellular region part | 4 | 3.77358490566037 | 0.91939116292412 | VCAM1, LAMA4, SPARCL1, LOXL1 | 74 | 960 | 12782 | 0.719707207207207 | 1 | 0.999694647560879 | 99.9999999999989
Annotation Cluster 42 | Enrichment Score: 0.1402562570104888
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0043065~positive regulation of apoptosis | 3 | 2.83018867924528 | 0.720826373334647 | DUSP1, RBM5, ABL1 | 80 | 430 | 13528 | 1.17976744186046 | 1 | 0.999440176461138 | 99.9999996919802
GOTERM_BP_FAT | GO:0043068~positive regulation of programmed cell death | 3 | 2.83018867924528 | 0.724419101337112 | DUSP1, RBM5, ABL1 | 80 | 433 | 13528 | 1.17159353348729 | 1 | 0.999451921642903 | 99.9999997475509
GOTERM_BP_FAT | GO:0010942~positive regulation of cell death | 3 | 2.83018867924528 | 0.726792886038222 | DUSP1, RBM5, ABL1 | 80 | 435 | 13528 | 1.16620689655172 | 1 | 0.999449734287227 | 99.9999997789633
Annotation Cluster 43 | Enrichment Score: 0.1114749094499841
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_BP_FAT | GO:0006793~phosphorus metabolic process | 6 | 5.66037735849056 | 0.680166546101606 | DUSP1, GNAI2, ENPP2, NDUFC2, [NAME], ABL1 | 80 | 973 | 13528 | 1.04275436793422 | 1 | 0.999034979789024 | 99.9999975135232
GOTERM_BP_FAT | GO:0006796~phosphate metabolic process | 6 | 5.66037735849056 | 0.680166546101606 | DUSP1, GNAI2, ENPP2, NDUFC2, [NAME], ABL1 | 80 | 973 | 13528 | 1.04275436793422 | 1 | 0.999034979789024 | 99.9999975135232
GOTERM_BP_FAT | GO:0016310~phosphorylation | 4 | 3.77358490566037 | 0.853831260891507 | GNAI2, NDUFC2, [NAME], ABL1 | 80 | 800 | 13528 | 0.8455 | 1 | 0.999961759826097 | 99.9999999999851
GOTERM_BP_FAT | GO:0006468~protein amino acid phosphorylation | 3 | 2.83018867924528 | 0.906771321088753 | GNAI2, [NAME], ABL1 | 80 | 667 | 13528 | 0.760569715142428 | 1 | 0.999994292552664 | 99.9999999999999
Annotation Cluster 44 | Enrichment Score: 0.08382366736497372
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0016564~transcription repressor activity | 4 | 3.77358490566037 | 0.315454599476291 | PBXIP1, RUNX1T1, SCMH1, ENO1 | 82 | 316 | 12983 | 2.00416795307193 | 1 | 0.947373783415146 | 99.1418236031145
GOTERM_MF_FAT | [NAME]~transcription activator activity | 3 | 2.83018867924528 | 0.730287347584508 | KLF6, NPM1, NFE2L2 | 82 | 410 | 12983 | 1.15850684116597 | 1 | 0.998663245465444 | 99.9999928333518
GOTERM_MF_FAT | GO:0003700~transcription factor activity | 6 | 5.66037735849056 | 0.737303555811619 | KLF6, FOS, RUNX1T1, NFE2L2, SCMH1, ENO1 | 82 | 975 | 12983 | 0.974333958724202 | 1 | 0.998620410333056 | 99.9999948524039
GOTERM_MF_FAT | GO:0030528~transcription regulator activity | 9 | 8.49056603773585 | 0.74107970044851 | HMGN1, KLF6, FOS, PBXIP1, NPM1, RUNX1T1, NFE2L2, SCMH1, ENO1 | 82 | 1512 | 12983 | 0.942436120789779 | 1 | 0.998494750853851 | 99.9999957079842
GOTERM_BP_FAT | GO:0031328~positive regulation of cellular biosynthetic process | 4 | 3.77358490566037 | 0.770355891893435 | KLF6, FOS, NPM1, NFE2L2 | 80 | 685 | 13528 | 0.987445255474452 | 1 | 0.999758835627846 | 99.9999999846626
GOTERM_BP_FAT | GO:0045893~positive regulation of transcription, DNA-dependent | 3 | 2.83018867924528 | 0.772821875398228 | KLF6, FOS, NFE2L2 | 80 | 477 | 13528 | 1.06352201257861 | 1 | 0.99975942556803 | 99.9999999870064
GOTERM_BP_FAT | GO:0051254~positive regulation of RNA metabolic process | 3 | 2.83018867924528 | 0.776838885365251 | KLF6, FOS, NFE2L2 | 80 | 481 | 13528 | 1.05467775467775 | 1 | 0.999769261491602 | 99.9999999901208
GOTERM_BP_FAT | GO:0009891~positive regulation of biosynthetic process | 4 | 3.77358490566037 | 0.778890555015251 | KLF6, FOS, NPM1, NFE2L2 | 80 | 695 | 13528 | 0.973237410071942 | 1 | 0.999767747473834 | 99.9999999914275
GOTERM_BP_FAT | GO:0006357~regulation of transcription from RNA polymerase II promoter | 4 | 3.77358490566037 | 0.804494686422036 | KLF6, FOS, ABL1, ENO1 | 80 | 727 | 13528 | 0.930398899587345 | 1 | 0.999858984516281 | 99.9999999987054
GOTERM_BP_FAT | GO:0045941~positive regulation of transcription | 3 | 2.83018867924528 | 0.847341839731235 | KLF6, FOS, NFE2L2 | 80 | 564 | 13528 | 0.899468085106382 | 1 | 0.999960610981018 | 99.999999999971
GOTERM_BP_FAT | GO:0051252~regulation of RNA metabolic process | 9 | 8.49056603773585 | 0.847801731334477 | KLF6, FOS, NPM1, RBM5, RUNX1T1, YWHAQ, NFE2L2, [NAME], ENO1 | 80 | 1813 | 13528 | 0.839437396580253 | 1 | 0.99995853171668 | 99.9999999999723
GOTERM_BP_FAT | GO:0010628~positive regulation of gene expression | 3 | 2.83018867924528 | 0.859055361425333 | KLF6, FOS, NFE2L2 | 80 | 581 | 13528 | 0.87314974182444 | 1 | 0.999966245349861 | 99.9999999999915
GOTERM_BP_FAT | GO:0045935~positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 3 | 2.83018867924528 | 0.885152338477762 | KLF6, FOS, NFE2L2 | 80 | 624 | 13528 | 0.812980769230769 | 1 | 0.999986672070987 | 99.9999999999996
GOTERM_BP_FAT | GO:0051173~positive regulation of nitrogen compound metabolic process | 3 | 2.83018867924528 | 0.8957221379726 | KLF6, FOS, NFE2L2 | 80 | 644 | 13528 | 0.787732919254658 | 1 | 0.999991292104159 | 99.9999999999999
GOTERM_BP_FAT | GO:0010557~positive regulation of macromolecule biosynthetic process | 3 | 2.83018867924528 | 0.900666035329446 | KLF6, FOS, NFE2L2 | 80 | 654 | 13528 | 0.775688073394495 | 1 | 0.99999268661369 | 99.9999999999999
SP_PIR_KEYWORDS | transcription regulation | 8 | 7.54716981132075 | 0.935086685353272 | KLF6, FOS, DPY30, BTG2, RUNX1T1, NFE2L2, SCMH1, ENO1 | 106 | 2026 | 19235 | 0.716534113133043 | 1 | 0.999963984437748 | 99.9999999999999
SP_PIR_KEYWORDS | dna-binding | 7 | 6.60377358490566 | 0.94911471386301 | HMGN1, KLF6, FOS, ERCC5, RUNX1T1, NFE2L2, ENO1 | 106 | 1868 | 19235 | 0.67999777786756 | 1 | 0.999982505963308 | 100
GOTERM_BP_FAT | GO:0045449~regulation of transcription | 11 | 10.377358490566 | 0.954504436409451 | KLF6, FOS, PBXIP1, BTG2, NPM1, RUNX1T1, YWHAQ, NFE2L2, ABL1, SCMH1, ENO1 | 80 | 2601 | 13528 | 0.71514801999231 | 1 | 0.999999836363104 | 100
GOTERM_BP_FAT | GO:0006355~regulation of transcription, DNA-dependent | 7 | 6.60377358490566 | 0.956663492335259 | KLF6, FOS, RUNX1T1, YWHAQ, NFE2L2, [NAME], ENO1 | 80 | 1773 | 13528 | 0.667625493513818 | 1 | 0.999999858684142 | 100
GOTERM_BP_FAT | GO:0010604~positive regulation of macromolecule metabolic process | 3 | 2.83018867924528 | 0.964317567408733 | KLF6, FOS, NFE2L2 | 80 | 857 | 13528 | 0.591948658109684 | 1 | 0.999999940944107 | 100
GOTERM_MF_FAT | GO:0003677~DNA binding | 10 | 9.43396226415094 | 0.966953002109588 | HMGN1, KLF6, FOS, ERCC5, RBM5, RUNX1T1, NFE2L2, ABL1, SCMH1, ENO1 | 82 | 2331 | 12983 | 0.67923324020885 | 1 | 0.999999214407593 | 100
SP_PIR_KEYWORDS | Transcription | 7 | 6.60377358490566 | 0.975344046534462 | KLF6, DPY30, BTG2, RUNX1T1, NFE2L2, SCMH1, ENO1 | 106 | 2071 | 19235 | 0.613344205242203 | 1 | 0.999998096909137 | 100
GOTERM_BP_FAT | GO:0006350~transcription | 6 | 5.66037735849056 | 0.99630461930537 | KLF6, BTG2, RUNX1T1, NFE2L2, SCMH1, ENO1 | 80 | 2101 | 13528 | 0.482912898619704 | 1 | 0.999999999998994 | 100
Annotation Cluster 45 | Enrichment Score: 0.047999753177705454
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
GOTERM_MF_FAT | GO:0046872~metal ion binding | 24 | 22.6415094339622 | 0.78543427141994 | MYL6, [NAME], S100A6, CAPNS1, [NAME], ATP1B3, ENPP2, SPARCL1, RBM5, RUNX1T1, ACTN1, CPXM2, ANXA4, ERCC5, PGM5, CALML4, [NAME], U2AF1, ZRANB1, ABL1, LOXL1, S100A2, INO80B, ENO1 | 82 | 4140 | 12983 | 0.917850830682219 | 1 | 0.999146400091016 | 99.9999995943501
GOTERM_MF_FAT | GO:0043169~cation binding | 24 | 22.6415094339622 | 0.801853388283076 | MYL6, [NAME], S100A6, CAPNS1, [NAME], ATP1B3, ENPP2, SPARCL1, RBM5, RUNX1T1, ACTN1, CPXM2, ANXA4, ERCC5, PGM5, CALML4, [NAME], U2AF1, ZRANB1, ABL1, LOXL1, S100A2, INO80B, ENO1 | 82 | 4179 | 12983 | 0.909285101465515 | 1 | 0.999301363637424 | 99.9999998506862
GOTERM_MF_FAT | GO:0043167~ion binding | 24 | 22.6415094339622 | 0.826244351332629 | MYL6, [NAME], S100A6, CAPNS1, [NAME], ATP1B3, ENPP2, SPARCL1, RBM5, RUNX1T1, ACTN1, CPXM2, ANXA4, ERCC5, PGM5, CALML4, [NAME], U2AF1, ZRANB1, ABL1, LOXL1, S100A2, INO80B, ENO1 | 82 | 4241 | 12983 | 0.895992086541945 | 1 | 0.999540441791405 | 99.9999999712987
SP_PIR_KEYWORDS | metal-binding | 14 | 13.2075471698113 | 0.843766730121476 | KLF6, S100A6, [NAME], [NAME], RUNX1T1, RBM5, ERCC5, PGM5, U2AF1, ZRANB1, ABL1, LOXL1, INO80B, ENO1 | 106 | 2972 | 19235 | 0.854802051855049 | 1 | 0.999424342761906 | 99.9999999942468
SP_PIR_KEYWORDS | zinc-finger | 6 | 5.66037735849056 | 0.963383743574832 | KLF6, U2AF1, RBM5, RUNX1T1, ZRANB1, INO80B | 106 | 1718 | 19235 | 0.63374481077163 | 1 | 0.999993613139665 | 100
GOTERM_MF_FAT | GO:0046914~transition metal ion binding | 11 | 10.377358490566 | 0.988080565410526 | KLF6, S100A6, [NAME], U2AF1, RBM5, RUNX1T1, ZRANB1, CPXM2, ABL1, LOXL1, INO80B | 82 | 2785 | 12983 | 0.625357971712571 | 1 | 0.999999983092755 | 100
GOTERM_MF_FAT | GO:0008270~zinc ion binding | 8 | 7.54716981132075 | 0.993716127520147 | KLF6, S100A6, U2AF1, RBM5, RUNX1T1, ZRANB1, CPXM2, INO80B | 82 | 2311 | 12983 | 0.548089202224778 | 1 | 0.999999998097811 | 100
SP_PIR_KEYWORDS | zinc | 6 | 5.66037735849056 | 0.994517086606798 | KLF6, U2AF1, RBM5, RUNX1T1, ZRANB1, INO80B | 106 | 2189 | 19235 | 0.497384004068369 | 1 | 0.999999963174937 | 100
Annotation Cluster 46 | Enrichment Score: 0.046916674016988624
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | Secreted | 10 | 9.43396226415094 | 0.58060943711394 | C10ORF57, LAMA4, ENPP2, SPARCL1, CSNK2B, CPXM2, LRRC17, C4BPA, LOXL1, PLAC9 | 106 | 1689 | 19235 | 1.07437693399019 | 1 | 0.981902345411935 | 99.9983901698133
GOTERM_CC_FAT | GO:0005576~extracellular region | 11 | 10.377358490566 | 0.730943949592247 | VCAM1, C10ORF57, LAMA4, ENPP2, SPARCL1, CSNK2B, CPXM2, ACTN1, C4BPA, LOXL1, PLAC9 | 74 | 2010 | 12782 | 0.945287078122899 | 1 | 0.990102147840365 | 99.999994800026
GOTERM_CC_FAT | GO:0044421~extracellular region part | 4 | 3.77358490566037 | 0.91939116292412 | VCAM1, LAMA4, SPARCL1, LOXL1 | 74 | 960 | 12782 | 0.719707207207207 | 1 | 0.999694647560879 | 99.9999999999989
SP_PIR_KEYWORDS | signal | 11 | 10.377358490566 | 0.988971774433092 | VCAM1, C10ORF57, LAMA4, ENPP2, SPARCL1, CSNK2B, CPXM2, LRRC17, C4BPA, LOXL1, PLAC9 | 106 | 3250 | 19235 | 0.614179970972423 | 1 | 0.999999769393955 | 100
UP_SEQ_FEATURE | signal peptide | 11 | 10.377358490566 | 0.989745335712901 | VCAM1, C10ORF57, LAMA4, ENPP2, SPARCL1, CSNK2B, CPXM2, LRRC17, C4BPA, LOXL1, PLAC9 | 106 | 3250 | 19113 | 0.610284470246734 | 1 | 1 | 100
SP_PIR_KEYWORDS | disulfide bond | 9 | 8.49056603773585 | 0.993666524188841 | VCAM1, LAMA4, ATP1B3, ENPP2, SPARCL1, NPM1, CSNK2B, CPXM2, C4BPA | 106 | 2924 | 19235 | 0.558536380765557 | 1 | 0.999999954199865 | 100
UP_SEQ_FEATURE | disulfide bond | 8 | 7.54716981132075 | 0.99670267144856 | VCAM1, LAMA4, ATP1B3, ENPP2, SPARCL1, CSNK2B, CPXM2, C4BPA | 106 | 2819 | 19113 | 0.511702932258863 | 1 | 1 | 100
SP_PIR_KEYWORDS | glycoprotein | 10 | 9.43396226415094 | 0.999953743257569 | VCAM1, LAMA4, ATP1B3, ENPP2, SPARCL1, TSPAN6, CSNK2B, CPXM2, C4BPA, ANXA4 | 106 | 4318 | 19235 | 0.420246095764111 | 1 | 0.999999999999976 | 100
UP_SEQ_FEATURE | glycosylation site:N-linked (GlcNAc...) | 9 | 8.49056603773585 | 0.999972116715528 | VCAM1, LAMA4, ATP1B3, ENPP2, SPARCL1, TSPAN6, CSNK2B, CPXM2, C4BPA | 106 | 4129 | 19113 | 0.393025402468503 | 1 | 1 | 100
Annotation Cluster 47 | Enrichment Score: 9.270817666164494E-4
Category | Term | Count | % | PValue | Genes | List Total | Pop Hits | Pop Total | Fold Enrichment | [NAME] | [NAME] | [NAME]
SP_PIR_KEYWORDS | membrane | 25 | 23.5849056603773 | 0.988838211404236 | [NAME], [NAME], [NAME], ATP1B3, TSPAN6, VPS33B, VCAM1, RHOB, KDELR1, MANBAL, TMEM14C, ENO1, C10ORF57, CAPNS1, TMEM93, NDUFC2, DENND1A, KRTCAP2, DHRS3, SPCS2, LGTN, ABL1, SEC61G, PMEPA1, COG1 | 106 | 6256 | 19235 | 0.725152909810355 | 1 | 0.999999811406157 | 100
UP_SEQ_FEATURE | transmembrane region | 15 | 14.1509433962264 | 0.999361233302815 | RTN4, C10ORF57, ATP1B3, TMEM93, TSPAN6, NDUFC2, KRTCAP2, VCAM1, DHRS3, SPCS2, MANBAL, KDELR1, TMEM14C, PMEPA1, SEC61G | 106 | 4911 | 19113 | 0.550737082329618 | 1 | 1 | 100
SP_PIR_KEYWORDS | [NAME] | 15 | 14.1509433962264 | 0.999434758431948 | RTN4, C10ORF57, ATP1B3, TMEM93, TSPAN6, NDUFC2, KRTCAP2, VCAM1, DHRS3, SPCS2, MANBAL, KDELR1, TMEM14C, PMEPA1, SEC61G | 106 | 4973 | 19235 | 0.547342441637673 | 1 | 0.999999999956767 | 100
UP_SEQ_FEATURE | topological domain:Cytoplasmic | 8 | 7.54716981132075 | 0.999713467960966 | [NAME], VCAM1, ATP1B3, TSPAN6, SPCS2, KDELR1, SEC61G, PMEPA1 | 106 | 3374 | 19113 | 0.427531288096542 | 1 | 1 | 100
GOTERM_CC_FAT | GO:0031224~intrinsic to membrane | 17 | 16.0377358490566 | 0.999951754160482 | RTN4, C10ORF57, ATP1B3, [NAME], TMEM93, TSPAN6, NDUFC2, KRTCAP2, VCAM1, DHRS3, RHOB, SPCS2, MANBAL, KDELR1, TMEM14C, PMEPA1, SEC61G | 74 | 5485 | 12782 | 0.535351942644558 | 1 | 0.99999999999995 | 100
GOTERM_CC_FAT | GO:0016021~integral to membrane | 16 | 15.0943396226415 | 0.9999556341287 | RTN4, C10ORF57, ATP1B3, [NAME], TMEM93, TSPAN6, NDUFC2, KRTCAP2, VCAM1, DHRS3, SPCS2, MANBAL, KDELR1, TMEM14C, PMEPA1, SEC61G | 74 | 5297 | 12782 | 0.521743567241018 | 1 | 0.999999999999941 | 100