Spreadsheet: 0e26dee2-3d59-4bf4-8733-b59e20dedf48
Sheet: added reactions

ID | Reaction ID | Name | Preferred Name | Definition | Eqaution | Reversiblity | direction | compartment | GeneId | PreferredECNumber | KEGGallECNo | Ecnumber | [NAME] | bits | E-val or source
R0912 | R03472 | NO NAME | NO NAME | 4-Amino-5-hydroxymethyl-2-methylpyrimidine <=> Aminoimidazole ribotide | C01279 <=> C03373 | irev | Backward | c |  |  |  |  | Thiamine metabolism
R0913 | R02721 | NO NAME | NO NAME | D-Glyceraldehyde 3-phosphate + Pyruvate <=> 5-(2-Hydroxyethyl)-4-methylthiazole | C00118 + C00022 <=> C04294 | irev | Forward | c |  |  |  |  | Thiamine metabolism
R0303 |  | D-Glyceraldehyde:NAD+ oxidoreductase | D-Glyceraldehyde:NAD+ oxidoreductase | glyald[c] + h[c] + nadh[c]  -> nad[c] + glyc[c] |  | r |  | c | (YALI0B01298g or YALI0C03025g or YALI0E00264g or YALI0F23793g) |  | 1.2.1.3 |  | Tryptophan metabolism |  | IKU-IKReaction,n-1-n
R0944 | R04982 | NO NAME | NO NAME | 2-Hexaprenyl-6-methoxyphenol + Oxygen <=> 2-Hexaprenyl-6-methoxy-1,4-benzoquinone + H2O | C05802 + C00007 <=> C05803 + C00001 | irev | Forward | m | YALI0A09042g |  |  |  | Ubiquinone and other terpenoid-quinone biosynthesis
R0888 | R01914 | Spermidine:(acceptor) oxidoreductase | Spermidine:(acceptor) oxidoreductase | [NAME] H2O <=> 1,3-Diaminopropane + 4-Aminobutyraldehyde + Hydrogen peroxide | C00315 + C00007 + C00001 <=> C00986 + C00555 + C00027 | irev | Forward | c | YALI0B00726g | 1.5.99.6 | 1.5.99.6 | 1.5.99.6 | beta-Alanine metabolism
R0696 | R02978 | Sphinganine:NADP+ 3-oxidoreductase | Sphinganine:NADP+ 3-oxidoreductase | Sphinganine + NADP+ <=> 3-Dehydrosphinganine + NADPH + H+ | C00836 + C00006 <=> C02934 + C00005 + C00080 | irev | Backward | c | YALI0B17688g | 1.1.1.102 | 1.1.1.102 | 1.1.1.102 | Sphingolipid metabolism | 130 | 2e-31
R0900 | R03531 | 2'-Deoxyinosine-5'-triphosphate pyrophosphohydrolase | 2'-Deoxyinosine-5'-triphosphate pyrophosphohydrolase | dITP + H2O <=> 2'-Deoxyinosine 5'-phosphate + Diphosphate | C01345 + C00001 <=> C06196 + C00013 | irev | Forward | c | YALI0B22924g | 3.6.1.19 | 3.6.1.19 | 3.6.1.19 | Purine metabolism
R0341 |  | [NAME], yeast-specific | [NAME], yeast-specific | (0.01) 12dgr_SC + cdpchol --> cmp + h + (0.01) pc_SC |  | irev | Forward | c | YALI0C10989g | 2.7.8.2 | 2.7.8.2 |  | Glycerophospholipid metabolism | 307 | 2e-84
R0342 |  | Ethanolaminephosphotransferase, yeast-specific | Ethanolaminephosphotransferase, yeast-specific | (0.01) 12dgr_SC + cdpea <==> cmp + h + (0.01) pe_SC |  | r |  | c | YALI0C10989g | 2.7.8.1 | 2.7.8.1 |  | Glycerophospholipid metabolism | 307 | 2e-84
R0945 | R04983 | NO NAME | NO NAME | 2-Hexaprenyl-6-methoxy-1,4-benzoquinone + S-Adenosyl-L-methionine <=> 2-Hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-Adenosyl-L-homocysteine | C05803 + C00019 <=> C05804 + C00021 | irev | Forward | m | YALI0C18205g |  |  |  | Ubiquinone and other terpenoid-quinone biosynthesis
R0936 |  | Dolichyl-phosphate-mannose--protein mannosyltransferase, | Dolichyl-phosphate-mannose--protein mannosyltransferase, | Dolichyl phosphate D-mannose <=> Dolichyl phosphate + H + mannan | C03862 <=> C00110 + C00080 + C00464 | irev | Forward | c | YALI0C23364g OR YALI0E05929g OR YALI0E15081g | 2.4.1.109 | 2.4.1.109 | 2.4.1.109 | N-Glycan biosynthesis
R0887 | R01954 | L-Citrulline:L-aspartate ligase (AMP-forming) | L-Citrulline:L-aspartate ligase (AMP-forming) | ATP + L-Citrulline + L-Aspartate <=> AMP + Diphosphate + N-(L-Arginino)succinate | C00002 + C00327 + C00049 <=> C00020 + C00013 + C03406 | r |  | c | [NAME] | 6.3.4.5 | 6.3.4.5 | 6.3.4.5 | Arginine and proline metabolism | 29 | 1.4
R0421 |  | L-2-Aminoadipate-6-semialdehyde:NAD+ 6-oxidoreductase | L-2-Aminoadipate-6-semialdehyde:NAD+ 6-oxidoreductase | L2aadp[c] + atp[c] + h[c] + nadh[c]  -> L2aadp6sa[c] + amp[c] + nad[c] + ppi[c] |  | r |  | c | [NAME] |  | 1.2.1.31 |  | Pyrimidine metabolism |  | IKU-IKUReaction,1-1-n
R0422 |  | L-2-Aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase | L-2-Aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase | L2aadp[c] + atp[c] + h[c] + nadph[c]  -> L2aadp6sa[c] + amp[c] + nadp[c] + ppi[c] |  | r |  | c | [NAME] |  | 1.2.1.31 |  | Lysine biosynthesis |  | IKU-IKUReaction,1-1-n
R0893 |  | methylene-fatty-acyl-phospholipid synthase, yeast-specific | methylene-fatty-acyl-phospholipid synthase, yeast-specific | amet + (0.01) ptdmeeta_SC --> ahcys + h + (0.01) ptd2meeta_SC |  | irev | Forward | c | YALI0E12441g | 2.1.1.6 | 2.1.1.6 | 2.1.1.16 | Glycerophospholipid metabolism
R0894 |  | Phosphatidyl-N-methylethanolamine N-methyltransferase, yeast-specific | Phosphatidyl-N-methylethanolamine N-methyltransferase, yeast-specific | amet + (0.01) ptd2meeta_SC --> ahcys + h + (0.01) pc_SC |  | irev | Forward | c | YALI0E12442g | 2.1.1.6 | 2.1.1.6 | 2.1.1.16 | Glycerophospholipid metabolism
R0946 | R04984 | NO NAME | NO NAME | 2-Hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + Oxygen + NADPH + H+ <=> 2-Hexaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone + NADP+ + H2O | C05804 + C00007 + C00005 + C00080 <=> C05805 + C00006 + C00001 | irev | Forward | m | YALI0E15224g |  |  |  | Ubiquinone and other terpenoid-quinone biosynthesis
R0718 |  | mannose-(inositol-P)2-ceramide synthase (ceramide-1, 24C), yeast-specific | mannose-(inositol-P)2-ceramide synthase (ceramide-1, 24C), yeast-specific | (0.01) mipc124_SC + (0.01) ptd1ino_SC --> (0.01) 12dgr_SC + (0.01) mip2c124_SC |  | irev | Forward | c | [NAME] |  |  |  | Sphingolipid metabolism | 105 | 2e-23
R0719 |  | mannose-(inositol-P)2-ceramide synthase (ceramide-1, 26C), yeast-specific | mannose-(inositol-P)2-ceramide synthase (ceramide-1, 26C), yeast-specific | (0.01) mipc126_SC + (0.01) ptd1ino_SC --> (0.01) 12dgr_SC + (0.01) [NAME] |  | irev | Forward | c | [NAME] |  |  |  | Sphingolipid metabolism | 105 | 2e-23
R0720 |  | mannose-(inositol-P)2-ceramide synthase (ceramide-2, 26C), yeast specific | mannose-(inositol-P)2-ceramide synthase (ceramide-2, 26C), yeast specific | (0.01) mipc224_SC + (0.01) ptd1ino_SC --> (0.01) 12dgr_SC + (0.01) mip2c224_SC |  | irev | Forward | c | [NAME] |  |  |  | Sphingolipid metabolism | 105 | 2e-23
R0721 |  | mannose-(inositol-P)2-ceramide synthase (ceramide-2, 24C), yeast-specific | mannose-(inositol-P)2-ceramide synthase (ceramide-2, 24C), yeast-specific | (0.01) mipc226_SC + (0.01) ptd1ino_SC --> (0.01) 12dgr_SC + (0.01) [NAME] |  | irev | Forward | c | [NAME] |  |  |  | Sphingolipid metabolism | 105 | 2e-23
R0722 |  | mannose-(inositol-P)2-ceramide synthase (ceramide-3, 24C), yeast specific | mannose-(inositol-P)2-ceramide synthase (ceramide-3, 24C), yeast specific | (0.01) mipc324_SC + (0.01) ptd1ino_SC --> (0.01) 12dgr_SC + (0.01) mip2c324_SC |  | irev | Forward | c | [NAME] |  |  |  | Sphingolipid metabolism | 105 | 2e-23
R0723 |  | mannose-(inositol-P)2-ceramide synthase (ceramide-3, 26C), yeast-specific | mannose-(inositol-P)2-ceramide synthase (ceramide-3, 26C), yeast-specific | (0.01) mipc326_SC + (0.01) ptd1ino_SC --> (0.01) 12dgr_SC + (0.01) mip2c326_SC |  | irev | Forward | c | [NAME] |  |  |  | Sphingolipid metabolism | 105 | 2e-23
R0908 | [NAME] | 3-sn-phosphatidate phosphohydrolase | 3-sn-phosphatidate phosphohydrolase | Sphinganine 1-phosphate + H2O <=> Sphinganine + Orthophosphate | C01120 + C00001 <=> C00836 + C00009 | irev | Forward | c | YALI0E21197g | 3.1.3.4，3.1.3.- | 3.1.3.4 | 3.1.3.4 | Sphingolipid metabolism | 206 | 6e-54
R0940 | R05616 | NO NAME | NO NAME | all-trans-Hexaprenyl diphosphate + 4-Hydroxybenzoate <=> 3-Hexaprenyl-4-hydroxybenzoate + Diphosphate | C01230 + C00156 <=> C13425 + C00013 | irev | Forward | m | YALI0F05610g | 2.5.1.39 | 2.5.1.39 | 2.5.1.39 | Ubiquinone and other terpenoid-quinone biosynthesis
R0712 |  | mannose-inositiol phophorylceramide synthase (ceramide-1, 24C), yeast-specific | mannose-inositiol phophorylceramide synthase (ceramide-1, 24C), yeast-specific | gdpmann + (0.01) ipc124_SC --> gdp + h + (0.01) mipc124_SC |  | irev | Forward | c | YALI0F07260g AND YALI0F16093g |  |  |  | Sphingolipid metabolism | 42 | 0.0002
R0713 |  | mannose-inositol phosphorylceramide synthase (ceramide-1, 26C), yeast-specific | mannose-inositol phosphorylceramide synthase (ceramide-1, 26C), yeast-specific | gdpmann + (0.01) ipc126_SC --> gdp + h + (0.01) mipc126_SC |  | irev | Forward | c | YALI0F07260g AND YALI0F16093g |  |  |  | Sphingolipid metabolism | 42 | 0.0002
R0714 |  | mannose-inositol phosphorylceramide synthase (ceramide-2, 24C), yeast-specific | mannose-inositol phosphorylceramide synthase (ceramide-2, 24C), yeast-specific | gdpmann + (0.01) ipc224_SC --> gdp + h + (0.01) mipc224_SC |  | irev | Forward | c | YALI0F07260g AND YALI0F16093g |  |  |  | Sphingolipid metabolism | 42 | 0.0002
R0715 |  | mannose-inositol phosphorylceramide synthase (ceramide-2, 26C), yeast-specific | mannose-inositol phosphorylceramide synthase (ceramide-2, 26C), yeast-specific | gdpmann + (0.01) ipc226_SC --> gdp + h + (0.01) mipc226_SC |  | irev | Forward | c | YALI0F07260g AND YALI0F16093g |  |  |  | Sphingolipid metabolism | 42 | 0.0002
R0716 |  | mannose-inositol phosphorylceramide synthase (ceramide-3, 24C), yeast-specific | mannose-inositol phosphorylceramide synthase (ceramide-3, 24C), yeast-specific | gdpmann + (0.01) ipc324_SC --> gdp + h + (0.01) mipc324_SC |  | irev | Forward | c | YALI0F07260g AND YALI0F16093g |  |  |  | Sphingolipid metabolism | 42 | 0.0002
R0717 |  | mannose-inositol phosphorylceramide synthase (ceramide-3, 26C), yeast-specific | mannose-inositol phosphorylceramide synthase (ceramide-3, 26C), yeast-specific | gdpmann + (0.01) ipc326_SC --> gdp + h + (0.01) mipc326_SC |  | irev | Forward | c | YALI0F07260g AND YALI0F16093g |  |  |  | Sphingolipid metabolism | 42 | 0.0002
R0895 | R01315 | [NAME] | [NAME] | Phosphatidylcholine + H2O <=> 1-Acyl-sn-glycero-3-phosphocholine + Fatty acid | C00157 + C00001 <=> C04230 + C00162 | irev | Forward | c | [NAME] | 3.1.1.4 | 3.1.1.4 | 3.1.1.4 | Glycerophospholipid metabolism
R0226 |  | acyl-CoA thioesterase | acyl-CoA thioesterase | dcacoa + h2o --> coa + dca + h |  | irev | Forward | m | YALI0F14729g | 3.1.2.2 | 3.1.2.2 | 3.1.2.2 | Fatty acid metabolism | 112 | 8e-26
[NAME] |  | acyl-CoA thioesterase | acyl-CoA thioesterase | ddcacoa + h2o --> coa + ddca + h |  | irev | Forward | m | YALI0F14729g | 3.1.2.2 | 3.1.2.2 | 3.1.2.2 | Fatty acid metabolism | 112 | 8e-26
R0228 |  | acyl-CoA thioesterase | acyl-CoA thioesterase | h2o + ttccoa --> coa + h + ttc |  | irev | Forward | m | YALI0F14729g | 3.1.2.2 | 3.1.2.2 | 3.1.2.2 | Fatty acid metabolism | 112 | 8e-26
R0229 |  | acyl-CoA thioesterase | acyl-CoA thioesterase | h2o + pmtcoa --> coa + h + hdca |  | irev | Forward | m | YALI0F14729g | 3.1.2.2 | 3.1.2.2 | 3.1.2.2 | Fatty acid metabolism | 112 | 8e-26
R0230 |  | acyl-CoA thioesterase | acyl-CoA thioesterase | h2o + tdcoa --> coa + h + ttdca |  | irev | Forward | m | YALI0F14729g | 3.1.2.2 | 3.1.2.2 | 3.1.2.2 | Fatty acid metabolism | 112 | 8e-26
[NAME] |  | acyl-CoA thioesterase | acyl-CoA thioesterase | h2o + stcoa --> coa + h + ocdca |  | irev | Forward | m | YALI0F14729g | 3.1.2.2 | 3.1.2.2 | 3.1.2.2 | Fatty acid metabolism | 112 | 8e-26
R0232 |  | acyl-CoA thioesterase | acyl-CoA thioesterase | h2o + occoa --> coa + h + octa |  | irev | Forward | m | YALI0F14729g | 3.1.2.2 | 3.1.2.2 | 3.1.2.2 | Fatty acid metabolism | 112 | 8e-26
R0892 | R00899 | L-cysteinylglycine dipeptidase | L-cysteinylglycine dipeptidase | [NAME] H2O <=> L-Cysteine + Glycine | C01419 + C00001 <=> C00097 + C00037 | r |  | c | YALI0F17842g | 3.4.11.1，3.4.11.2，3.4.11.23，3.4.13.3 | 3.4.11.1 | DUG1 | Glutathione metabolism
R0889 | R00714 | Succinate-semialdehyde:NADP+ oxidoreductase | Succinate-semialdehyde:NADP+ oxidoreductase | Succinate semialdehyde + NADP+ + H2O <=> Succinate + NADPH + H+ | [NAME] C00001 <=> C00042 + C00005 + C00080 | irev | Forward | c | YALI0F26191g | 1.2.1.16 | 1.2.1.16 | 1.2.1.16 | Butanoate metabolism | 588 | e-168
R0907 | R00188 | Adenosine 3',5'-bisphosphate 3'-phosphohydrolase | Adenosine 3',5'-bisphosphate 3'-phosphohydrolase | Adenosine 3',5'-bisphosphate + H2O <=> AMP + Orthophosphate | C00054 + C00001 <=> C00020 + C00009 | irev | Forward | c | YALI0F27665g | 3.1.3.7 | 3.1.3.7 | 3.1.3.7 | Sulfur metabolism
R0891 | R05553 | 4-amino-4-deoxychorismate pyruvate-lyase | 4-amino-4-deoxychorismate pyruvate-lyase | 4-Amino-4-deoxychorismate <=> 4-Aminobenzoate + Pyruvate | C11355 <=> C00568 + C00022 | irev | Forward | c |  | 4.1.3.38 | 4.1.3.38 | 4.1.3.38 | Folate biosynthesis
R0896 | R06982 | S-(hydroxymethyl)glutathione synthase | S-(hydroxymethyl)glutathione synthase | Glutathione + Formaldehyde <=> S-(Hydroxymethyl)glutathione | C00051 + C00067 <=> C14180 | r |  | c |  | 4.4.1.22 | 4.4.1.22 |  | Methane metabolism
R0897 | R03444 | 2-Hydroxybutane-1,2,4-tricarboxylate hydro-lyase | 2-Hydroxybutane-1,2,4-tricarboxylate hydro-lyase | (R)-2-Hydroxybutane-1,2,4-tricarboxylate <=> (Z)-But-1-ene-1,2,4-tricarboxylate + H2O | C01251 <=> C04002 + C00001 | r |  | m |  | 4.2.1.114 | 4.2.1.114 |  | Lysine biosynthesis
R0420 | R01939 | L-2-aminoadipate:2-oxoglutarate aminotransferase | L-2-aminoadipate:2-oxoglutarate aminotransferase | L-2-Aminoadipate + 2-Oxoglutarate <=> 2-Oxoadipate + L-Glutamate | C00956 + C00026 <=> C00322 + C00025 | r |  | c |  | 2.6.1.39 | 2.6.1.39 |  | Lysine biosynthesis
R0899 | R02556 | [NAME] aminohydrolase | [NAME] aminohydrolase | [NAME] + H2O <=> Deoxyinosine + NH3 | C00559 + C00001 <=> C05512 + C00014 | r |  | c |  | 3.5.4.4 | 3.5.4.4 |  | Purine metabolism
R0901 | R06604 | 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase | 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase | 5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate <=> (S)(+)-Allantoin + CO2 | C12248 <=> C02350 + C00011 | irev | Forward | c |  | 4.1.1.- | 4.1.1.- |  | Purine metabolism
R0902 | R00102 | NAD+ glycohydrolase | NAD+ glycohydrolase | NAD+ + H2O <=> Nicotinamide + ADP-ribose | C00003 + C00001 <=> C00153 + C00301 | irev | Forward | c |  | 3.2.2.5，3.2.2.6 | 3.2.2.5 |  | Purine metabolism
R0903 | R03509 | N-(5-Phospho-beta-D-ribosyl)anthranilate ketol-isomerase | N-(5-Phospho-beta-D-ribosyl)anthranilate ketol-isomerase | N-(5-Phospho-D-ribosyl)anthranilate <=> 1-(2-Carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate | C04302 <=> C01302 | r |  | c |  | 5.3.1.24 | 5.3.1.24 |  | Phenylalanine, tyrosine and tryptophan biosynthesis
R0904 | R02296 | Cytidine:orthophosphate alpha-D-ribosyltransferase | Cytidine:orthophosphate alpha-D-ribosyltransferase | Cytidine + Orthophosphate <=> Cytosine + alpha-D-Ribose 1-phosphate | C00475 + C00009 <=> C00380 + C00620 | r |  | c |  | 2.4.2.2 | 2.4.2.2 |  | Pyrimidine metabolism
R0905 | R01876 | Uridine:phosphate alpha-D-ribosyltransferase | Uridine:phosphate alpha-D-ribosyltransferase | Uridine + Orthophosphate <=> Uracil + alpha-D-Ribose 1-phosphate | C00299 + C00009 <=> C00106 + C00620 | r |  | c |  | 2.4.2.3 | 2.4.2.3 |  | Pyrimidine metabolism
R0906 | R07280 | NO NAME | NO NAME | 5-Amino-6-(5'-phospho-D-ribitylamino)uracil + H2O <=> 5-Amino-6-(1-D-ribitylamino)uracil + Orthophosphate | C04454 + C00001 <=> C04732 + C00009 | irev | Forward | c |  | 3.1.3.- | 3.1.3.- |  | [NAME] metabolism |  | IKU-IKReaction | 1-1-1
[NAME] | R01825 | D-erythrose 4-phosphate:NAD+ oxidoreductase | D-erythrose 4-phosphate:NAD+ oxidoreductase | D-Erythrose 4-phosphate + NAD+ + H2O <=> 4-Phospho-D-erythronate + NADH + H+ | C00279 + C00003 + C00001 <=> C03393 + C00004 + C00080 | r |  | c |  | 1.2.1.72 | 1.2.1.72 |  | [NAME] metabolism
R0911 | R04210 | 4-phospho-D-erythronate:NAD+ 2-oxidoreductase | 4-phospho-D-erythronate:NAD+ 2-oxidoreductase | 4-Phospho-D-erythronate + NAD+ <=> 2-Oxo-3-hydroxy-4-phosphobutanoate + NADH + H+ | C03393 + C00003 <=> C06054 + C00004 + C00080 | r |  | c |  | 1.1.1.290 | 1.1.1.290 |  | [NAME] metabolism
R0914 | R02133 | [NAME] hydrolase | [NAME] hydrolase | Thiamine + H2O <=> 4-Amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-Hydroxyethyl)-4-methylthiazole + H+ | C00378 + C00001 <=> C01279 + C04294 + C00080 | irev | Forward | c |  | 3.5.99.2 | 3.5.99.2 |  | Thiamine metabolism
R0915 | R00617 | ATP:thiamin-phosphate phosphotransferase | ATP:thiamin-phosphate phosphotransferase | ATP + Thiamin monophosphate <=> ADP + Thiamin diphosphate | C00002 + C01081 <=> C00008 + C00068 | irev | Forward | c |  | 2.7.4.16 | 2.7.4.16 |  | Thiamine metabolism
R0916 | R01974 | 3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming] | 3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming] | Indolepyruvate <=> Indole-3-acetaldehyde + CO2 | C00331 <=> C00637 + C00011 | irev | Forward | c |  | 4.1.1.43，4.1.1.74 | 4.1.1.43 |  | Tryptophan metabolism
R0917 | R03889 | 2-Aminomuconate semialdehyde:NAD+ 6-oxidoreductase | 2-Aminomuconate semialdehyde:NAD+ 6-oxidoreductase | 2-Aminomuconate semialdehyde + NAD+ + H2O <=> 2-Aminomuconate + H+ + NADH | C03824 + C00003 + C00001 <=> C02220 + C00080 + C00004 | irev | Forward | c |  | 1.2.1.32 | 1.2.1.32 |  | Tryptophan metabolism
R0918 | R04323 | 2-Amino-3-carboxymuconate semialdehyde carboxy-lyase | 2-Amino-3-carboxymuconate semialdehyde carboxy-lyase | 2-Amino-3-carboxymuconate semialdehyde <=> 2-Aminomuconate semialdehyde + CO2 | C04409 <=> C03824 + C00011 | irev | Forward | c |  | 4.1.1.45 | 4.1.1.45 |  | Tryptophan metabolism
R0919 | R01937 | NO NAME | NO NAME | 2-Oxoadipate + NH3 + NAD+ <=> 2-Aminomuconate + NADH + H+ + H2O | C00322 + C00014 + C00003 <=> C02220 + C00004 + C00080 + C00001 | irev | Backward | c |  | 1.5.1.- | 1.5.1.- |  | Tryptophan metabolism
R0921 | R02519 | Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) | Homogentisate:oxygen 1,2-oxidoreductase (decyclizing) | Homogentisate + Oxygen <=> 4-Maleylacetoacetate | C00544 + C00007 <=> C01036 | irev | Forward | c |  | 1.13.11.5 | 1.13.11.5 |  | Tyrosine metabolism
R0922 | R03181 | 4-Maleylacetoacetate cis-trans-isomerase | 4-Maleylacetoacetate cis-trans-isomerase | 4-Maleylacetoacetate <=> 4-Fumarylacetoacetate | C01036 <=> C01061 | irev | Forward | c |  | 5.2.1.2 | 5.2.1.2 |  | Tyrosine metabolism
R0923 | R01364 | 4-fumarylacetoacetate fumarylhydrolase | 4-fumarylacetoacetate fumarylhydrolase | Acetoacetate + Fumarate <=> 4-Fumarylacetoacetate + H2O | C00164 + C00122 <=> C01061 + C00001 | irev | Backward | c |  | 3.7.1.2 | 3.7.1.2 |  | Tyrosine metabolism
R0924 | R04426 | 3-Isopropylmalate:NAD+ oxidoreductase | 3-Isopropylmalate:NAD+ oxidoreductase | (2R,3S)-3-Isopropylmalate + NAD+ <=> (2S)-2-Isopropyl-3-oxosuccinate + NADH + H+ | C04411 + C00003 <=> C04236 + C00004 + C00080 | r |  | c |  | 1.1.1.85 | 1.1.1.85 |  | [NAME], leucine and isoleucine biosynthesis
R0925 | R02085 | (S)-3-Hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming) | (S)-3-Hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming) | (S)-3-Hydroxy-3-methylglutaryl-CoA <=> 3-Methylglutaconyl-CoA + H2O | C00356 <=> C03231 + C00001 | r |  | c |  | 4.2.1.18 | 4.2.1.18 |  | [NAME], leucine and isoleucine degradation
R0926 | R02661 | 2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase | 2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase | 2-Methylpropanoyl-CoA + FAD <=> 2-Methylprop-2-enoyl-CoA + FADH2 | C00630 + C00016 <=> C03460 + C01352 | r |  | c |  | 1.3.99.2，1.3.99.3，1.3.99.12，1.3.99.- | 1.3.99.2 |  | [NAME], leucine and isoleucine degradation
R0927 | R05064 | (S)-3-Hydroxyisobutyryl-CoA hydrolase | (S)-3-Hydroxyisobutyryl-CoA hydrolase | (S)-3-Hydroxyisobutyryl-CoA + H2O <=> CoA + (S)-3-Hydroxyisobutyrate | C06000 + C00001 <=> C00010 + C06001 | irev | Forward | c |  | 3.1.2.4 | 3.1.2.4 |  | [NAME], leucine and isoleucine degradation
R0928 | [NAME] | (S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase | (S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase | (S)-2-Methylbutanoyl-CoA + FAD <=> 2-Methylbut-2-enoyl-CoA + FADH2 | C15980 + C00016 <=> C03345 + C01352 | r |  | c |  | 1.3.99.2，1.3.99.3，1.3.99.12 | 1.3.99.2 |  | [NAME], leucine and isoleucine degradation
[NAME] | R04203 | (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase | (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase | (2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA + NAD+ <=> 2-Methylacetoacetyl-CoA + NADH + H+ | C04405 + C00003 <=> C03344 + C00004 + C00080 | r |  | c |  | 1.1.1.35，1.1.1.178 | 1.1.1.35 |  | [NAME], leucine and isoleucine degradation
R0930 | R00833 | (R)-Methylmalonyl-CoA CoA-carbonylmutase | (R)-Methylmalonyl-CoA CoA-carbonylmutase | (R)-Methylmalonyl-CoA <=> Succinyl-CoA | C01213 <=> C00091 | irev | Forward | c |  | 5.4.99.2 | 5.4.99.2 |  | [NAME], leucine and isoleucine degradation
R0948 | [NAME] | acetyl-CoA:L-serine O-acetyltransferase | acetyl-CoA:L-serine O-acetyltransferase | L-Serine + Acetyl-CoA <=> O-Acetyl-L-serine + CoA | C00065 + C00024 <=> C00979 + C00010 | r |  | c |  | 2.3.1.30 | 2.3.1.30 |  | Cysteine and methionine metabolism
R1312 |  | orotidine-5'-phosphate carboxy-lyase (UMP-forming) | orotidine-5'-phosphate carboxy-lyase (UMP-forming) | orot5p[c] + h[c] <=> ump[c] + co2[c] |  | r |  | c
R1314 |  | catalase | catalase | (2) h2o2[c] -> (2) h2o[c] + o2[c] |  | irev | Forward | c |  |  |  |  | Lysine biosynthesis
[NAME] |  | catalase | catalase | (2) h2o2[m] -> (2) h2o[m] + o2[m] |  | irev | Forward | c |  |  |  |  | Tryptophan metabolism
[NAME] |  | Glycerol dehydrogenase (NADP-dependent) | Glycerol dehydrogenase (NADP-dependent) | glyc[c] + nadp[c] -> dha[c] + h[c] + nadph[c] |  | irev | Forward | c |  |  |  |  | Glycerolipid metabolism
R1323 |  | ATP:N-acetyl-D-glucosamine 6-phosphotransferase | ATP:N-acetyl-D-glucosamine 6-phosphotransferase | atp[c] + acgam[c] -> adp[c] + acgam6p[c] +h[c] |  | irev | Forward | c |  |  |  |  | Glycerolipid Metabolism
R0946 |  | 5-Methyltetrahydrofolate:L-homocysteine S-methyltransferase | 5-Methyltetrahydrofolate:L-homocysteine S-methyltransferase | 5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine |  | r |  | c |  | 2.1.1.13 | 2.1.1.13 |  | Amino sugar and nucleotide sugar metabolism
 |  |  |  |  |  |  |  |  |  |  |  |  | Ubiquinone and other terpenoid-quinone biosynthesis