Spreadsheet: 855ef95b-1b44-4ea7-8f31-883762459b31
Sheet: Sheet1

Test Referenced | Entry Type | Mayo ID | Description | Reporting Description | Method | Collection Container | Temperature | Stability | [NAME] | Unit of Measure | [NAME] | Minimum Volume | Reject Due To | Reference Values | Days/Times Performed | Analytic Time | Maximum Lab Time | CPT Units | CPT Code | LOINC® Code | LOINC® Attributes | Always Performed | Orderable Separately | Performing Location
VWPR | Test | VWPR | von Willebrand Profile | von Willebrand Prof | F8A, F8IS, IBETH: Activated Partial Thromboplastin Time-Based Clotting Assay VWAG: Automated Latex Immunoassay (LIA) VWFX: Latex Particle Enhanced Immunoassay RIST: Ristocetin Induced Aggregation of Washed Normal Platelets VWFM: Agarose Gel Electrophoresis/Infrared Dye-Labeled Antibody Detection | Light blue-top (citrate) tube: LgtBlu |  |  | 3 | mL | See Coagulation Studies in Special Instructions.   Specimen Type: Platelet-poor plasma Collection Container/Tube: Light-blue top (citrate) Submission Container/Tube: Plastic vials [NAME]: 3 mL in 3 plastic vials each containing 1 mL Collection Instructions: 1. Specimen must be drawn prior to factor replacement therapy. 2. Spin down, remove plasma, and spin plasma again. 3. Freeze specimens immediately at < or =-40 degrees C, if possible. 4. Send specimens in the same shipping container. Additional Information: 1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results. 2. If priority specimen, mark request form, give reason, and request a call-back. 3. Each coagulation assay requested should have its own vial. 4. If multiple coagulation profiles are ordered, each profile must be on a separate order. Forms: Coagulation Patient Information Sheet (Supply T675) in Special Instructions | 2 mL in 2 plastic vials each con | Hemolysis	Mild OK; Gross reject Thawing	Warm reject; Cold reject Lipemia	Mild OK; Gross reject Icterus	Mild OK: Gross reject Other	NA | FACTOR VIII ACTIVITY 55-200%   von WILLEBRAND FACTOR ACTIVITY 55-200%   von WILLEBRAND FACTOR ANTIGEN 55-200% | Monday through Friday; Varies |  |  |  | Profile |  |  |  |  | Rochester
VWPR | [NAME] | NACIT | [NAME] |  |  |  | Frozen | 14 days
VWPR | Component | F8A | Coagulation Factor VIII Activity Assay, Plasma | Coag Factor VIII Activity Assay, P | Activated Partial Thromboplastin Clot-Based Assay | Light blue-top (citrate) tube: LgtBlu |  |  | 1 | mL | See Coagulation Studies in Special Instructions.   Specimen Type: Platelet-poor plasma Collection Container/Tube: Light-blue top (citrate) Submission Container/Tube: Plastic vial [NAME]: 1 mL Collection Instructions: 1. Spin down, remove plasma, and spin plasma again.  2. Freeze specimen immediately at < or =-40 degrees C, if possible. Additional Information: 1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results. 2. Patient must not be receiving [NAME] or heparin therapy. 3. Each coagulation assay requested should have its own vial. 4. If priority specimen, mark request form, give reason, and request a call-back. 5. Not offered for detection of hemophilia carrier. 6. Coagulation testing is highly complex, often requiring the performance of multiple assays and correlation with clinical information. For that reason, we suggest ordering Coagulation Consultations. | 0.5 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm reject; Cold reject Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Adults: 55-200% Normal, full-term newborn infants or healthy premature infants usually have normal or elevated factor [NAME].* *See Pediatric Hemostasis References in Coagulation Studies in Special Instructions. | Monday through Friday | 1 day | 3 days | 1 | 85240 |  |  | Yes | Yes
F8A | [NAME] | NACIT | [NAME] |  |  |  | Frozen | 14 days
F8A | Result | F8A | Coag Factor VIII Activity Assay, P | Coag Factor VIII Activity Assay, P | Numeric |  |  |  |  | % |  |  |  |  |  |  |  |  |  | 3209-4 | Coagulation factor VIII activity actual/Normal:RelTime:Pt:PPP:Qn:Coag
VWPR | Component | VWAG | von Willebrand Factor [NAME], Plasma | von Willebrand Factor Ag, P | Automated Latex Immunoassay (LIA) | Light blue-top (citrate) tube: LgtBlu |  |  | 1 | mL | See Coagulation Studies in Special Instructions.   Specimen Type: Platelet-poor plasma Collection Container/Tube: Light-blue top (citrate) Submission Container/Tube: Plastic vial [NAME]: 1 mL Collection Instructions: 1. Spin down, remove plasma, and spin plasma again.  2. Freeze specimen immediately at < or =-40 degrees C, if possible. Additional Information: 1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results. 2. Each coagulation assay requested should have its own vial. 3. Tests for VWFX / von Willebrand Factor Activity, [NAME] and F8A / Coagulation Factor VIII Activity Assay, Plasma are recommended in conjunction with [NAME] antigen. | 0.5 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm reject; Cold OK - refreeze - note to lab Lipemia	Mild OK; Gross reject Icterus	NA Other	NA | 55-200% Note: Individuals of blood group "O" may have lower plasma von Willebrand factor (VWF) antigen than those of other ABO blood groups, such that apparently normal individuals of blood group "O" may have plasma VWF antigen as low as 40% to 50%, whereas the lower limit of the reference range for individuals of other blood groups may be 60% to 70%. Children: [NAME], infants, and children have normal or mildly increased plasma VWF antigen, with respect to the adult reference range. | Monday through Saturday | 1 day | 3 days | 1 | 85246 |  |  | Yes | Yes
VWAG | [NAME] | NACIT | [NAME] |  |  |  | Frozen | 14 days
VWAG | Result | VWAG | von Willebrand Factor Ag, P | von Willebrand Factor Ag, P | Numeric |  |  |  |  | % |  |  |  |  |  |  |  |  |  | 27816-8 | [NAME] factor [NAME] actual/Normal:RelMCnc:Pt:PPP:Qn:Imm
VWPR | Component | VWFX | von Willebrand Factor Activity, Plasma | von Willebrand Factor Activity, P | Latex Particle Enhanced Immunoassay |  |  |  | 1 | mL | See Coagulation Studies in Special Instructions.    Specimen Type: Platelet-poor plasma Collection Container/Tube: Light-blue top (citrate) Submission Container/Tube: Plastic vial [NAME]: 2 mL in 2 plastic vials each containing 1 mL Collection Instructions: 1. Specimen must be drawn prior to factor replacement therapy. 2. Spin down, remove plasma, and spin plasma again. 3. Freeze specimens immediately at < or =-40 degrees C, if possible. 4. Send specimens in the same shipping container. Additional Information: 1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results. 2. Each coagulation assay requested should have its own vial. 3. Tests for F8A / Coagulation Factor VIII Activity Assay, [NAME] and VWAG / von Willebrand Factor [NAME], Plasma are recommended in conjunction with [NAME] activity. | 0.5 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm reject; Cold OK refreeze - note to lab Lipemia	Mild OK; Gross reject Icterus	NA Other	NA | 55-200%   Normal, full-term newborn infants may have mildly increased levels which reach adult levels by 90 days postnatal. Healthy, premature infants (30-36 weeks gestation) may have increased levels that reach adult levels by 180 days. Note: Individuals of blood group "O" may have lower plasma von Willebrand factor (VWF) activity than those of other ABO blood groups, such that apparently normal individuals of blood group "O" may have plasma VWF activity as low as 40% to 50%, whereas the lower limit of the reference range for individuals of other blood groups may be 60% to 70%. | Monday through Saturday | 1 day | 3 days | 1 | 85397 |  |  | Yes | Yes
VWFX | [NAME] | NACIT | [NAME] |  |  |  | Frozen | 14 days
VWFX | Result | VWFX | von Willebrand Factor Activity, P | von Willebrand Factor Activity, P | Numeric |  |  |  |  | % |  |  |  |  |  |  |  |  |  | 68324-3 | [NAME] factor [NAME] actual/Normal:RelMCnc:Pt:PPP:Qn:Imm
VWFX | [NAME] | RIST | [NAME], Plasma | [NAME], P | Ristocetin Induced Agglutination of Washed Normal Platelets | Light blue-top (citrate) tube: LgtBlu |  |  | 1 | mL | See Coagulation Studies in Special Instructions.   Specimen Type: Platelet-poor plasma Collection Container/Tube: Light-blue top (sodium citrate) Submission Container/Tube: Plastic vial [NAME]: 1 mL Collection Instructions:  1. Fasting. 2. Spin down, remove plasma, and spin plasma again. 3. Freeze specimen immediately at < or =-40 degrees C, if possible. Additional Information:  1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results. 2. Each coagulation assay requested should have its own vial. 3. Tests for F8A/9070 Coagulation Factor VIII Activity Assay, [NAME] and [NAME], Plasma are recommended in conjunction with ristocetin cofactor. 4. Coagulation testing is highly complex, often requiring the performance of multiple assays and correlation with clinical information. For that reason, we suggest ordering VWPR/83099 von Willebrand Profile. | 0.5 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm reject; Cold OK-refreeze-note to lab Lipemia	Mild OK; Gross reject Icterus	NA Other	NA | Adults: 55-200% Note: Individuals of blood group "O" may have lower plasma von Willebrand factor (VWF) ristocetin cofactor activity than those of other ABO blood groups, such that apparently normal individuals of blood group "O" may have plasma VWF ristocetin cofactor activity as low as 40% to 50%, whereas the lower limit of the reference range for individuals of other blood groups may be 60% to 70%.   Normal, full-term newborn infants or healthy premature infants usually have levels in the adult range. | Monday through Friday; p.m. | 1 day | 7 days | 1 | 85245 |  |  | No | No
RIST | [NAME] | NACIT | [NAME] |  |  |  | Frozen | 14 days
RIST | Result | 9046 | [NAME], P | [NAME], P | Numeric |  |  |  |  | % |  |  |  |  |  |  |  |  |  | 6014-5 | [NAME] cofactor activity actual/Normal:RelTime:Pt:PPP:Qn:[NAME]
VWPR | Component | CCC1 | Interpretation | Interpretation | Interpretive reports on tests performed in Mayo's Special Coag Lab. |  |  |  |  |  | Ordered as part of Mayo Coagulation Profiles. |  |  |  | Special Coag |  |  |  |  |  |  | Yes | No
CCC1 | [NAME] | NACIT | [NAME] |  |  |  | Frozen | 14 days
CCC1 | Result | 7525 | Interpretation | Interpretation | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 69049-5
CCC1 | Result | 7769 | Reviewed by: | Reviewed by: | Alphanumeric
VWPR | [NAME] | IBETH | Bethesda Units | Bethesda Units | Clot-Based Assay | Light blue-top (citrate) tube: LgtBlu |  |  | 3 | mL |  |  | Specimens other than	Plasma Anticoagulants other than	Sodium citrate Hemolysis	Mild OK; Gross reject Thawing	Warm reject; Cold reject Lipemia	Mild OK; Gross reject Icteric	Mild OK; Gross reject | 0 unit | Monday through Friday | 2 days | 5 days | 1 | 85335 |  |  | No | No
IBETH | [NAME] | NACIT | [NAME] |  |  |  | Frozen | 14 days
IBETH | Result | 7288 | Bethesda Units | Bethesda Units | Numeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 13591-3 | Factor inhibitor [NAME]:ACnc:Pt:PPP:Qn:Coag
VWPR | [NAME] | F8IS | Coagulation Factor VIII Inhibitor Screen, Plasma | Coag Factor VIII Assay [NAME],P | Clot-Based Assay | Light blue-top (citrate) tube: LgtBlu |  |  | 3 | mL | See Coagulation Studies in Special Instructions.   Specimen Type: Platelet-poor plasma Collection Container/Tube: Light-blue top (citrate) Submission Container/Tube: Plastic vials [NAME]: 3 mL in 3 plastic vials each containing 1 mL Collection Instructions: 1. Specimen must be drawn prior to factor replacement therapy. 2. Spin down, remove plasma, and spin plasma again. 3. Freeze specimens immediately at < or =-40 degrees C, if possible. 4. Send specimens in the same shipping container. Additional Information: 1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results. 2. If priority specimen, mark request form, give reason, and request a call-back. 3. Each coagulation assay requested should have its own vial. | 2.0 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm reject; Cold reject Lipemia	Mild OK; Gross reject Icterus	Mild OK; Gross reject Other	NA | Negative If positive, quantitated in Bethesda units. | Monday through Friday | 1 day | 3 days | 1 | 85335 |  |  | No | No
F8IS | [NAME] | NACIT | [NAME] |  |  |  | Frozen | 14 days
F8IS | Result | 7289 | Coag Factor VIII Assay [NAME],P | Coag Factor VIII Assay [NAME],P | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 3206-0 | Coagulation factor VIII inhibitor:ACnc:Pt:PPP:Ord:Coag
VWPR | [NAME] | RIST | [NAME], Plasma | [NAME], P | Ristocetin Induced Agglutination of Washed Normal Platelets | Light blue-top (citrate) tube: LgtBlu |  |  | 1 | mL | See Coagulation Studies in Special Instructions.   Specimen Type: Platelet-poor plasma Collection Container/Tube: Light-blue top (sodium citrate) Submission Container/Tube: Plastic vial [NAME]: 1 mL Collection Instructions:  1. Fasting. 2. Spin down, remove plasma, and spin plasma again. 3. Freeze specimen immediately at < or =-40 degrees C, if possible. Additional Information:  1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results. 2. Each coagulation assay requested should have its own vial. 3. Tests for F8A/9070 Coagulation Factor VIII Activity Assay, [NAME] and [NAME], Plasma are recommended in conjunction with ristocetin cofactor. 4. Coagulation testing is highly complex, often requiring the performance of multiple assays and correlation with clinical information. For that reason, we suggest ordering VWPR/83099 von Willebrand Profile. | 0.5 mL | Hemolysis	Mild OK; Gross reject Thawing	Warm reject; Cold OK-refreeze-note to lab Lipemia	Mild OK; Gross reject Icterus	NA Other	NA | Adults: 55-200% Note: Individuals of blood group "O" may have lower plasma von Willebrand factor (VWF) ristocetin cofactor activity than those of other ABO blood groups, such that apparently normal individuals of blood group "O" may have plasma VWF ristocetin cofactor activity as low as 40% to 50%, whereas the lower limit of the reference range for individuals of other blood groups may be 60% to 70%.   Normal, full-term newborn infants or healthy premature infants usually have levels in the adult range. | Monday through Friday; p.m. | 1 day | 7 days | 1 | 85245 |  |  | No | No
RIST | [NAME] | NACIT | [NAME] |  |  |  | Frozen | 14 days
RIST | Result | 9046 | [NAME], P | [NAME], P | Numeric |  |  |  |  | % |  |  |  |  |  |  |  |  |  | 6014-5 | [NAME] cofactor activity actual/Normal:RelTime:Pt:PPP:Qn:[NAME]
VWPR | [NAME] | VWFM | von WillebrandFactor Multimer Analysis, Plasma | von Willebrand Factor Multimer, P | Agarose Gel Electrophoresis/Infrared Dye-Labeled Antibody Detection |  |  |  | 0.5 | mL | Only orderable as part of a coagulation consultation. | 0.5 mL | Specimens other than	Plasma Anticoagulants other than	Sodium citrate Hemolysis	Mild OK; Gross reject Thawing	Warm reject; Cold OK - refreeze & note to lab Lipemia	Mild OK; Gross reject Icteric	Mild OK; Gross reject | An interpretive report will be provided. | Monday, Tuesday | 7 days | 10 days | 1 | 85247 |  |  | No | Yes (order #8844)
VWFM | [NAME] | NACIT | [NAME] |  |  |  | Frozen | 14 days
VWFM | Result | 31046 | von Willebrand Factor Multimer, P | von Willebrand Factor Multimer, P | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 32217-2 | [NAME] factor multimers:ACnc:Pt:PPP:[NAME]:
VWPR | [NAME] | CCC2 | Special Coagulation Interpretation | Special Coagulation Interpretation | Only orderable as part of a reflex. |  |  |  |  |  | Only orderable as part of a reflex. |  |  |  | Monday through Friday; Varies |  |  | 1 | 85390 |  |  | No | No
CCC2 | [NAME] | NACIT | [NAME] |  |  |  | Frozen
CCC2 | Result | CCC2 | Special Coagulation Interpretation | Special Coagulation Interpretation | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 69049-5