Spreadsheet: 588c84be-d22b-4b7d-92b9-e218aa4f75fb
Sheet: Sheet1

Unnamed: 0 | Unnamed: 1 | Cmet | [NAME] | Cpin | [NAME]
1.A. α-Type channels
The Voltage-gated Ion Channel (VIC) Superfamily | 1.A.1 | 3 | 2 | 2 | 2
The Major Intrinsic Protein (MIP) Family | 1.A.8 | 2 | 1 | 1 | 1
The Ammonia Transporter Channel (Amt) Family | 1.A.11 | 2 | 2 | 2 | 2
The Large Conductance Mechanosensitive Ion Channel (MscL) Family | 1.A.22 | 1 | 1 | 1 | 1
The Small Conductance Mechanosensitive Ion Channel (MscS) Family | 1.A.23 | 9 | 8 | 9 | 8
The CorA Metal Ion Transporter (MIT) Family | 1.A.35 | 4 | 3 | 4 | 3
 | total | 21 | 17 | 19 | 17
2.A. Porters (uniporters, symporters, antiporters)
The Major Facilitator Superfamily (MFS) | 2.A.1 | 89 | 108 | 125 | 87
The Glycoside-Pentoside-Hexuronide (GPH):Cation Symporter Family | 2.A.2 | 0 | 0 | 1 | 0
The Amino Acid-Polyamine-Organocation (APC) Family | 2.A.3 | 6 | 8 | 9 | 8
The Cation Diffusion Facilitator (CDF) Family | 2.A.4 | 5 | 3 | 4 | 4
The Zinc (Zn2+)-Iron (Fe2+) Permease (ZIP) Family | 2.A.5 | 1 | 1 | 1 | 1
The Resistance-Nodulation-Cell Division (RND) Superfamily | 2.A.6 | 26 | 22 | 22 | 18
The Drug/Metabolite Transporter (DMT) Superfamily | 2.A.7 | 27 | 29 | 28 | 29
The Gluconate:H+ Symporter (GntP) Family | 2.A.8 | 3 | 3 | 2 | 2
The Cytochrome Oxidase Biogenesis (Oxa1) Family | 2.A.9 | 1 | 1 | 1 | 1
The 2-Keto-3-Deoxygluconate Transporter (KDGT) Family | 2.A.10 | 1 | 1 | 0 | 0
The Citrate-Mg2+:H+ (CitM) Citrate-Ca2+:H+ (CitH) Symporter (CitMHS) Family | 2.A.11 | 0 | 1 | 0 | 0
The ATP:ADP Antiporter (AAA) Family | 2.A.12 | 1 | 1 | 1 | 1
The Lactate Permease (LctP) Family | 2.A.14 | 2 | 2 | 2 | 2
The Telurite-resistance/Dicarboxylate Transporter (TDT) Family | 2.A.16 | 0 | 0 | 2 | 0
The Ca2+:Cation Antiporter ([NAME]) Family | 2.A.19 | 1 | 0 | 1 | 0
The Inorganic Phosphate Transporter ([NAME]) Family | 2.A.20 | 1 | 1 | 1 | 1
The Solute:Sodium Symporter (SSS) Family | 2.A.21 | 4 | 5 | 7 | 4
The Dicarboxylate/Amino Acid:Cation (Na+ or H+) Symporter (DAACS) Family | 2.A.23 | 5 | 6 | 5 | 3
The 2-Hydroxycarboxylate Transporter (2-HCT) Family | 2.A.24 | 1 | 0 | 0 | 0
The Glutamate:Na+ Symporter (ESS) Family | 2.A.27 | 0 | 1 | 0 | 1
The Bile Acid:Na+ Symporter (BASS) Family | 2.A.28 | 1 | 1 | 1 | 1
The NhaA Na+:H+ Antiporter (NhaA) Family | 2.A.33 | 0 | 1 | 0 | 0
The Monovalent Cation:Proton Antiporter-1 (CPA1) Family | 2.A.36 | 2 | 1 | 4 | 2
The Monovalent Cation:Proton Antiporter-2 (CPA2) Family | 2.A.37 | 5 | 5 | 5 | 4
The K+ Transporter (Trk) Family | 2.A.38 | 0 | 1 | 0 | 0
The Nucleobase:Cation Symporter-2 (NCS2) Family | 2.A.40 | 5 | 8 | 7 | 8
The Arsenite-Antimonite (ArsB) Efflux Family | 2.A.45 | 1 | 1 | 1 | 1
The Benzoate:H+ Symporter (BenE) Family | 2.A.46 | 1 | 1 | 2 | 1
The Divalent Anion:Na+ Symporter (DASS) Family | 2.A.47 | 4 | 2 | 1 | 1
The Chloride Carrier/Channel (ClC) Family | 2.A.49 | 3 | 1 | 3 | 2
The Chromate Ion Transporter (CHR) Family | 2.A.51 | 5 | 2 | 4 | 2
The Ni2+-Co2+ Transporter (NiCoT) Family | 2.A.52 | 1 | 2 | 0 | 0
The Sulfate Permease (SulP) Family | 2.A.53 | 6 | 4 | 5 | 3
The Metal Ion (Mn2+-iron) [NAME] (Nramp) Family | 2.A.55 | 0 | 0 | 2 | 1
The Tripartite ATP-independent [NAME] (TRAP-T) Family | 2.A.56 | 11 | 18 | 11 | 17
The Phosphate:Na+ Symporter (PNaS) Family | 2.A.58 | 2 | 2 | 1 | 1
The Arsenical Resistance-3 (ACR3) Family | 2.A.59 | 1 | 1 | 1 | 2
The Monovalent Cation (K+ or [NAME] (CPA3) Family | 2.A.63 | 0 | 9 | 7 | 7
The Twin Arginine Targeting (Tat) Family | 2.A.64 | 3 | 3 | 3 | 3
The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily | 2.A.66 | 7 | 7 | 6 | 6
The Oligopeptide Transporter (OPT) Family | 2.A.67 | 2 | 3 | 3 | 3
The Auxin Efflux Carrier (AEC) Family | 2.A.69 | 2 | 2 | 2 | 2
The Malonate:Na+ Symporter (MSS) Family | 2.A.70 | 0 | 0 | 2 | 0
The K+ Uptake Permease (KUP) Family | 2.A.72 | 1 | 3 | 1 | 1
The Short Chain Fatty Acid Uptake (AtoE) Family | 2.A.73 | 1 | 1 | 1 | 1
The L-Lysine Exporter (LysE) Family | 2.A.75 | 1 | 1 | 1 | 1
The Resistance to Homoserine/Threonine (RhtB) Family | 2.A.76 | 12 | 10 | 7 | 9
The Branched Chain Amino Acid Exporter (LIV-E) Family | 2.A.78 | 2 | 2 | 2 | 2
The Tricarboxylate Transporter (TTT) Family | 2.A.80 | 130 | 163 | 137 | 110
The Aspartate:Alanine Exchanger (AAE) Family | 2.A.81 | 2 | 3 | 3 | 3
The Aromatic Acid Exporter (ArAE) Family | 2.A.85 | 7 | 4 | 5 | 4
The Autoinducer-2 Exporter (AI-2E) Family (Formerly the PerM Family, TC #9.B.22) | 2.A.86 | 4 | 5 | 4 | 6
The Vacuolar Iron Transporter (VIT) Family | 2.A.89 | 1 | 1 | 0 | 0
 | total | 397 | 461 | 444 | 366
3.A. P-P-bond-hydrolysis-driven transporters
The ATP-binding Cassette (ABC) Superfamily | 3.A.1 | 264 | 354 | 296 | 283
The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily | 3.A.2 | 9 | 8 | 8 | 9
The P-type ATPase (P-ATPase) Superfamily | 3.A.3 | 13 | 11 | 10 | 6
The General Secretory Pathway (Sec) Family | 3.A.5 | 7 | 7 | 7 | 7
The Septal DNA Translocator (S-DNA-T) Family | 3.A.12 | 2 | 1 | 3 | 2
 | total | 295 | 381 | 324 | 307
4.A. [NAME]-driven group translocators
 | 4.A | 5 | 7 | 5 | 4
9.A. Recognized transporters of unknown biochemical mechanism
The MerTP Mercuric Ion (Hg2+) Permease (MerTP) Family | 9.A.2 | 4 | 0 | 1 | 0
The YggT or Fanciful K+ Uptake-B (FkuB; YggT) Family | 9.A.4 | 1 | 1 | 1 | 1
The Ferrous Iron Uptake (FeoB) Family | 9.A.8 | 1 | 1 | 2 | 1
The Iron/Lead Transporter (ILT) Superfamily | 9.A.10 | 2 | 0 | 0 | 0
The Putative 4-Toluene Sulfonate Uptake Permease (TSUP) Family | 9.A.29 | 8 | 10 | 10 | 9
The Tellurium Ion Resistance (TerC) Family | 9.A.30 | 3 | 4 | 3 | 3
The Pyocin R2 Phage P2 Tail Fiber Protein ([NAME]) Family | 9.A.33 | 0 | 0 | 0 | 1
The HlyC/CorC (HCC) Family | 9.A.40 | 4 | 3 | 3 | 3
The Capsular Polysaccharide Exporter (CPS-E) Family | 9.A.41 | 2 | 0 | 0 | 3
 | total | 25 | 19 | 20 | 21
 | TOTAL | 743 | 885 | 812 | 715
 | % | 11.7 | 13.6 | 12.6 | 12.1
sources: (1) http://www.membranetransport.org/   and   (2) http://www.tcdb.org/ | proteins | 6319 | 6626 | 6446 | 5897