Spreadsheet: 25fda7fb-86ad-4afc-8cc1-4a767d274b2c
Sheet: Sheet1

Table S1. O'Rourke et al. | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14 | Unnamed: 15 | Suppression | Localized | predicted to | dhc-1-
progeny counted (P), average embryonic viability (EV: % hatching) and standard deviations used for Figures 3A and 4. |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | tested with | with GFP | knockdown | specific
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | alleles | fusions | a second | ([NAME]. 4)
RNAi gene | or195 P | or195 EV | or195 EV SD | or283 P | or283 EV | or283 EV SD | or352 P | or352 EV | or352 EV SD | spn-4 P | spn-4 EV | spn-4 EV SD | lit-1 P | lit-1 EV | lit-1 EV SD | ([NAME]. 3B) | ([NAME]. 6) | gene
L4440 | 793 | 1.6 | 1.3 | 450 | 1.97 | 2.3 | 580 | 3.21 | 1.47 | 1986 | 6.1 | 5.28 | 2029 | 1.16 | 1.54
unc-15 | 132 | 100 | 0 | 19 | 100 | 0 | 155 | 100 | 0 | 22 | 100 | 0 | 75 | 55.56 | 52.7 |  |  |  | no
dylt-1 | 981 | 97.86 | 0.82 | 1022 | 91 | 0.15 | 764 | 92.35 | 0.74 | 2262 | 8.96 | 6.84 | 2388 | 0.41 | 0.79 | yes | yes |  | yes
C50D2.1 | 494 | 93.31 | 2.81 | 615 | 94.51 | 2.8 | 497 | 90.29 | 2.6 | 1567 | 15.01 | 3.74 | 999 | 55.83 | 12.92 |  |  |  | no
dpy-3 | 506 | 92.84 | 2.34 | 299 | 87.22 | 2.43 | 349 | 85.73 | 5.52 | 1022 | 33.02 | 13.92 | 1248 | 51.75 | 21.23 | yes |  |  | no
star-2 | 195 | 92.67 | 3.47 | 89 | 87.38 | 10.98 | 151 | 96.65 | 1.24 | 624 | 16.33 | 14.44 | 172 | 60.77 | 25.94 |  | yes |  | no
dpy-10 | 502 | 92.66 | 3.38 | 487 | 94.36 | 0.63 | 363 | 92.86 | 0.94 | 1102 | 20.75 | 14.08 | 1334 | 37.03 | 24.42 | yes |  |  | no
dyrb-1 | 1070 | 90.69 | 2.72 | 650 | 70.63 | 2.9 | 890 | 90 | 2.76 | 1673 | 4.33 | 3.17 | 2031 | 2.62 | 4.8 |  | yes |  | yes
efa-6 | 640 | 71.06 | 4.12 | 710 | 67.52 | 6.45 | 730 | 89.12 | 0.79 | 1580 | 3.85 | 1.97 | 2008 | 1.64 | 3.18 |  | yes |  | yes
mop-25.2 | 486 | 66.58 | 5.47 | 456 | 52.72 | 14.16 | 505 | 76.51 | 12.86 | 1661 | 13.77 | 7.91 | 1776 | 1.03 | 1.48 |  | yes |  | yes
osr-1 | 615 | 66.52 | 3.97 | 650 | 41.31 | 7.64 | 515 | 45.6 | 9.19 | 669 | 25.15 | 11.67 | 1229 | 14.42 | 10.48 |  |  |  | no
D2030.4 | 287 | 65.31 | 7.07 | 102 | 52.54 | 26.5 | 151 | 29.9 | 16.54 | 769 | 6.12 | 7.5 | 244 | 9.14 | 9.29 |  |  |  | no
F55A11.4 | 470 | 62.59 | 12.67 | 408 | 55.82 | 6.15 | 413 | 40.42 | 3.45 | 1746 | 25.64 | 9.23 | 1136 | 1.63 | 1.84 |  |  |  | no
Y110A7A.16 | 540 | 61.76 | 8.92 | 517 | 29.32 | 12.14 | 434 | 43.82 | 7.58 | 636 | 0.83 | 0.96 | 517 | 5.24 | 7.75 |  |  |  | no
vig-1 | 390 | 61.11 | 9.62 | 298 | 68.34 | 5.34 | 280 | 43.04 | 7.53 | 492 | 15.81 | 1.36 | 263 | 31.52 | 18.46 |  |  |  | no
M01F1.3 | 216 | 57.34 | 8.21 | 220 | 35.22 | 16.51 | 349 | 55.73 | 1.41 | 1085 | 6.64 | 9 | 1139 | 4.37 | 6.18 |  |  |  | no
tag-300 | 263 | 56.71 | 6.84 | 238 | 24.34 | 3.99 | 214 | 65.51 | 9.37 | 1212 | 6.15 | 3.05 | 620 | 21.04 | 12.8 |  |  | yes | no
ceh-18 | 353 | 56.56 | 9.07 | 356 | 26.54 | 9.23 | 301 | 20.28 | 5.74 | 1007 | 36.68 | 19.14 | 725 | 9.01 | 5.71 |  |  |  | no
F29C12.4 | 192 | 51.73 | 12.04 | 80 | 71.05 | 25.92 | 78 | 70.84 | 25.47 | 1113 | 7.99 | 6.08 | 330 | 3.27 | 5.77 |  |  |  | no
rpl-36 | 70 | 50.33 | 23.81 | 447 | 15.17 | 1.55 | 415 | 3.64 | 1.34 | 657 | 22.43 | 10.38 | 337 | 2.43 | 2.93 |  |  |  | no
F59A3.3 | 122 | 47.94 | 23.91 | 237 | 8.73 | 6.89 | 181 | 7.23 | 6.02 | 597 | 9.65 | 9.15 | 87 | 3.49 | 5.05 |  |  |  | no
C26E6.6 | 107 | 46.85 | 11.72 | 228 | 18.9 | 3.04 | 175 | 53.34 | 12.78 | 669 | 18.53 | 14.24 | 145 | 7.24 | 12.28 |  |  |  | no
tsfm-1 | 229 | 46.53 | 9.14 | 228 | 34.17 | 3.24 | 296 | 40.66 | 5.91 | 1406 | 10.19 | 8.52 | 591 | 22.53 | 9.38 |  |  |  | no
irs-2 | 106 | 39.9 | 1.94 | 375 | 9.34 | 4.11 | 236 | 15.69 | 2.15 | 1743 | 6.12 | 2.86 | 927 | 10.44 | 9.4 |  |  |  | no
cua-1 | 436 | 39.09 | 15.29 | 420 | 60.17 | 10.27 | 347 | 85.1 | 12.14 | 1544 | 13.18 | 10.69 | 580 | 1.24 | 1.93 |  |  |  | yes
C05D11.10 | 122 | 38.31 | 4.72 | 211 | 12.92 | 8.07 | 253 | 30.95 | 2.07 | 1180 | 12.89 | 10.65 | 612 | 5.47 | 7.4 |  |  |  | no
F10E7.8 | 645 | 37.92 | 6.55 | 515 | 46.31 | 7.32 | 485 | 67.89 | 8.32 | 1634 | 1.37 | 0.74 | 2011 | 0.06 | 0.19 |  | yes |  | yes
[NAME] | 168 | 36.63 | 2.92 | 228 | 21.74 | 8.75 | 82 | 21.28 | 20.15 | 157 | 0.96 | 1.19 | 27 | 3.51 | 7.47 |  |  |  | no
ufd-2 | 532 | 34.19 | 5.32 | 496 | 24.11 | 7.01 | 541 | 34.75 | 10.84 | 1769 | 13.89 | 10.52 | 1851 | 0.07 | 0.21 | yes |  |  | yes
Y63D3A.7 | 321 | 34.14 | 6.8 | 452 | 5.08 | 2.87 | 353 | 17.83 | 1.38 | 1505 | 8.72 | 8.4 | 1242 | 3.04 | 5.1 |  |  |  | no
T08B2.7/T08B2.8 | 39 | 29.04 | 25.22 | 67 | 5.59 | 5.29 | 47 | 7.33 | 7.15 | 134 | 2.27 | 4.55 | 35 | 45.41 | 42.52 |  |  |  | no
T23B12.3 | 398 | 28.55 | 5.5 | 97 | 28.45 | 18.97 | 67 | 35.39 | 15.02 | 1145 | 6.71 | 7 | 298 | 3.04 | 3.27 |  |  |  | no
W04B5.4 | 133 | 25.87 | 17 | 212 | 21.84 | 25.6 | 300 | 34.32 | 14.39 | 1376 | 9.52 | 9.44 | 635 | 1.99 | 2.53 |  |  |  | yes
F45H11.3 | 534 | 24.97 | 4.15 | 499 | 16.78 | 2.58 | 727 | 18.27 | 9.29 | 608 | 2.65 | 3.23 | 1401 | 0.1 | 0.24 |  |  |  | yes
inx-14 | 70 | 22.92 | 21.95 | 112 | 11.13 | 7.62 | 291 | 35.41 | 4.02 | 1473 | 8.93 | 3.77 | 1322 | 0.15 | 0.49 |  |  |  | yes
[NAME] | 628 | 22.4 | 6 | 506 | 13.03 | 3.82 | 465 | 13.83 | 6.06 | 2080 | 11.11 | 5.94 | 1920 | 1.46 | 2.27 |  |  |  | yes
sos-1 | 284 | 21.94 | 14.31 | 345 | 85.81 | 3.24 | 299 | 87.02 | 5.3 | 1531 | 22.6 | 9.61 | 396 | 1.38 | 1.35 |  |  |  | no
npp-22 | 384 | 20.55 | 4.59 | 494 | 26.94 | 7.56 | 405 | 37.83 | 3.39 | 1452 | 1.46 | 0.56 | 1691 | 0.06 | 0.2 |  | yes |  | yes
K04F10.3 | 639 | 20.03 | 6.87 | 533 | 19.3 | 1.63 | 444 | 56.7 | 12.99 | 867 | 3.19 | 1.35 | 1800 | 0 | 0 |  | yes |  | yes
T23D8.3 | 20 | 18.75 | 16.54 | 85 | 1.59 | 2.75 | 117 | 17.63 | 17.35 | 287 | 3.22 | 3.96 | 153 | 1.51 | 3.02 |  |  |  | yes
rpl-34/C42C1.3 | 189 | 17.85 | 5.57 | 141 | 21.04 | 6.51 | 187 | 24.96 | 10.88 | 390 | 0 | 0 | 97 | 0 | 0 |  |  |  | yes
rab-10 | 226 | 17.31 | 9.25 | 207 | 15.33 | 1.3 | 251 | 46.78 | 10.41 | 976 | 0.16 | 0.42 | 1096 | 0.54 | 0.66 |  |  |  | yes
H06O01.2 | 636 | 16.72 | 5.95 | 558 | 15.67 | 2.69 | 800 | 38.89 | 11.71 | 1975 | 13.16 | 4.8 | 1978 | 1.13 | 1.47 |  |  |  | yes
F25H5.6 | 324 | 16.48 | 9.79 | 152 | 16.5 | 8.58 | 221 | 15.65 | 11.41 | 429 | 16.47 | 14.58 | 137 | 4.55 | 5.25 |  |  |  | no
anc-1 | 514 | 11.89 | 4.37 | 527 | 5.06 | 2.89 | 405 | 3.77 | 3.41 | 698 | 1.16 | 0.67 | 755 | 0.71 | 1.29 |  |  |  | yes
R09B3.3 | 596 | 9.26 | 2.8 | 602 | 10.28 | 0.66 | 582 | 36.18 | 7.49 | 2355 | 21.22 | 8.02 | 2498 | 0.8 | 0.85 |  |  |  | no
ZK1127.10 | 472 | 6.75 | 3.87 | 445 | 7.81 | 1.16 | 352 | 9.11 | 0.79 | 1661 | 8.74 | 8.17 | 733 | 1.41 | 2.41 |  |  | yes | yes
ZK1236.5/ZK1236.9 | 439 | 6.75 | 1.04 | 335 | 10.47 | 7.47 | 436 | 5.87 | 0.98 | 617 | 2.57 | 2.12 | 354 | 1.13 | 0.89 |  |  |  | yes
Y40B1B.5 | 350 | 6.22 | 4.19 | 387 | 1.77 | 0.93 | 295 | 2.89 | 2.64 | 470 | 3.8 | 2.57 | 217 | 0.81 | 1.61 |  |  |  | no
F59C6.4 | 87 | 5.23 | 3.45 | 124 | 4.82 | 4.18 | 304 | 24.99 | 7.31 | 760 | 2.41 | 2.33 | 116 | 6.51 | 15.61 |  |  |  | no