Spreadsheet: 167c538e-58cf-46ca-a731-8e924dcb54af
Sheet: Table_t6v2.txt

Table S1.  Summary of proteins examined experimentally by COMBREX-funded projects.
UniProt Acc. | RefSeq Acc. | LocusTag | OrganismName | ClusterAcc | Cluster_Proteins | BlastHits | DUFs | HumanHomologs | Function Tested | Result
B0VN39 | YP_001708422.1 | ABSDF3356 | Acinetobacter baumannii SDF | CLSK903661 | 5 | 5 | – | – | Type IV restriction endonuclease AbaSI, hmC-specific | confirmed
F0KGN6 | YP_004996989.1 | [NAME] | Acinetobacter calcoaceticus PHEA-2 | – | 0 | 6 | – | – | Type IV restriction endonuclease AcaPI, hmC-specific | confirmed
Q9YDP0 | NP_147565.2 | APE_0875.1 | Aeropyrum pernix [NAME] | CLSK811317 | 3 | 1773 | – | HhH-GPD; EndIII_4Fe-2S | T•G specific glycosylase | no activity observed
A1K2B7 | YP_931859.1 | azo0355 | Azoarcus sp. BH72 | CLSK2307911 | 5 | 11 | – | – | Type IV restriction endonuclease AspBHI, recognizes YSm5CNS | confirmed
– | – | – | Azoarcus sp. BH72 | – | 0 | 0 | – | – | Restriction endonuclease AspBHII, recognizes RGGWCCY | confirmed
Q73EG5 | [NAME] | BCE_0393 | Bacillus cereus ATCC 10987 | CLSK925860 | 3 | 426 | – | DNA_methylase | DNA methyltransferase M.BceSV | confirmed
Q72ZR4 | NP_980897.1 | BCE_4604 | Bacillus cereus ATCC 10987 | CLSK829720 | 3 | 9 | – | – | Restriction endonuclease BceSII, recognizes GGWCC | confirmed
P25241 | NP_977342.1 | BCE_1019 | Bacillus cereus ATCC 10987 | CLSK877962 | 31 | 147 | – | ResIII; VRR_NUC | Restriction endonuclease [NAME], cleaves CGAAG(24-25/27-28) | confirmed
Q73EI9 | NP_976697.1 | [NAME] | Bacillus cereus ATCC 10987 | CLSK900064 | 8 | 9 | – | – | Restriction endonuclease subunit R2.BceSIV, cleaves (7/5)GCAGC(9/11) | confirmed
[NAME] | NP_976696.1 | BCE_0368 | Bacillus cereus ATCC 10987 | CLSK900065 | 8 | 50 | – | – | Restriction endonuclease subunit R1.BceSIV, cleaves (7/5)GCAGC(9/11) | confirmed
Q72WX3 | NP_981897.1 | [NAME] | Bacillus cereus ATCC 10987 | – | 1 | 5 | – | – | Restriction endonuclease [NAME], cleaves ACGGC(12/14) | confirmed
D5DK08 | YP_003598746.1 | BMD_3563 | Bacillus megaterium DSM 319 | – | 0 | 5 | – | – | Type IV restriction endonuclease BmeDI, hmC-specific | confirmed
Q02169 | NP_390683.1 | BSU28050 | Bacillus subtilis subsp. [NAME]. 168 | PRK00148 | 82 | 1080 | – | Maf | Maf phosphohydrolase | confirmed
Q5LDN4 | YP_211705.1 | BF2077 | Bacteroides fragilis NCTC 9343 | CLSK822567 | 7 | 8 | – | – | DNA methyltransferase modifying CCGG | no activity observed
Q64UQ9 | YP_099304.1 | BF2023 | Bacteroides fragilis YCH46 | CLSK822567 | 7 | 8 | – | – | DNA methyltransferase modifying CCGG | no activity observed
Q8A8L8 | NP_810062.1 | BT_1149 | Bacteroides thetaiotaomicron VPI-5482 | CLSK822567 | 7 | 8 | – | – | DNA methyltransferase modifying CCGG | no activity observed
A6L7D1 | YP_001301217.1 | BVU_3992 | Bacteroides vulgatus ATCC 8482 | CLSK822567 | 7 | 8 | – | – | DNA methyltransferase modifying CCGG | no activity observed
 |  |  | Bifidobacterium bifidum PRL2010 |  |  |  |  |  | Type IV restriction endonuclease | in progress
 |  |  | Bifidobacterium bifidum S17 |  |  |  |  |  | Type IV restriction endonuclease | in progress
Q89SE5 | NP_769095.1 | blr2455 | Bradyrhizobium japonicum USDA 110 | PRK06498 | 73 | 517 | – | – | Isocitrate lyase | confirmed
B4EJL0 | YP_002234131.1 | BCAM1520 | Burkholderia cenocepacia J2315 | CLSK928591 | 10 | 36 | – | HNH | Type IV restriction endonuclease BceJMcrA | no activity observed
B4E6M3 | YP_002232595.1 | BCAL3493 | Burkholderia cenocepacia J2315 | CLSK900148 | 33 | 150 | – | ResIII | Restriction endonuclease BceJI (type III RM), recognizes CACAG | no activity observed
B4E6M4 | YP_002232596.1 | BCAL3494 | Burkholderia cenocepacia J2315 | CLSK904033 | 22 | 362 | – | – | DNA methyltransferase M.BceJI (type III RM) modifying CACm6AG | confirmed
B4EK51 | YP_002234200.1 | BCAM1588 | Burkholderia cenocepacia J2315 | PRK06498 | 73 | 569 | – | – | Isocitrate lyase | in progress
B2T552 | YP_001895937.1 | Bphyt_2314 | Burkholderia phytofirmans PsJN | CLSK878064 | 58 | 382 | – | – | 2-nitropropane dioxygenase | in progress
[NAME] | YP_001890410.1 | Bphyt_6745 | Burkholderia phytofirmans PsJN | CLSK868522 | 5 | 623 | – | – | 2-nitropropane dioxygenase | in progress
B2TEK6 | YP_001887897.1 | Bphyt_4144 | Burkholderia phytofirmans PsJN | CLSK942171 | 9 | 644 | – | – | 2-nitropropane dioxygenase | in progress
Q9A7F9 | NP_420572.1 | CC_1764 | Caulobacter crescentus CB15 | PRK06498 | 73 | 635 | – | – | Isocitrate lyase | in progress
D5EQ08 | YP_003549911.1 | Caka_2726 | [NAME] akajimensis DSM 45221 | – | 0 | 21 | – | – | Type IV restriction endonuclease CakORF2727P | no activity observed
 |  |  | Corynebacterium kroppenstedtii DSM 44385 |  |  |  |  |  | Restriction endonuclease/methyltransferase | in progress
A3U4K6 | YP_003714853.1 | CA2559_00420 | Croceibacter atlanticus HTCC2559 | – | 1 | 12 | – | – | Restriction endonuclease CatHI, cleaves CTCTTC(1/4) | confirmed
Q24MI3 | YP_521202.1 | DSY4969 | Desulfitobacterium hafniense [NAME] | CLSK450859 | 4 | 38 | – | – | Trimethylamine (TMA):corrinoid methyltransferase | in progress
Q6ALL1 | YP_065771.1 | DP2035 | Desulfotalea psychrophila LSv54 | – | 1 | 125 | – | – | Type IV restriction endonuclease DpsMrrP | no activity observed
D4IB59 | YP_003537162.1 | EAM_0061 | [NAME] | – | 0 | 152 | – | – | Type IV restriction endonuclease EamBMcrBCP | no activity observed
B7LJ74 | YP_003162564.1 | pEC14_71 | Escherichia coli | CLSK861783 | 37 | 55 | – | – | [NAME]/cell adhesion protein | in progress
Q0TKS4 | YP_668356.1 | ECP_0424 | Escherichia coli 536 | CLSK908050 | 25 | 130 | – | – | [NAME]/cell adhesion protein | in progress
– | YP_003037476.1 | ECBD_3291 | Escherichia coli BL21(DE3) | CLSK879658 | 15 | 176 | – | – | [NAME]/cell adhesion protein | in progress
A7ZSG4 | YP_001464743.1 | EcE24377A_3754 | Escherichia coli E24377A | CLSK905348 | 23 | 1041 | – | SBP_bac_3 | ABC­type importer, periplasmic binding protein | in progress
B1X887 | YP_001731131.1 | ECDH10B_2348 | Escherichia coli str. K-12 substr. DH10B | CLSK880325 | 20 | 322 | – | – | ABC­type importer, periplasmic binding protein | in progress
P77269 | NP_417043.1 | b2548 (yphF) | Escherichia coli str. K-12 substr. MG1655 | CLSK880430 | 35 | 494 | – | – | ABC­type importer, periplasmic binding protein | in progress
[NAME] | NP_417492.1 | b3020 (ygiS) | Escherichia coli str. K-12 substr. MG1655 | PRK09755 | 24 | 3892 | – | – | ABC­type importer, periplasmic binding protein | in progress
P76042 | [NAME] | b1310 (ycjN) | Escherichia coli str. K-12 substr. MG1655 | CLSK880923 | 37 | 522 | – | – | ABC­type importer, periplasmic binding protein | in progress
P0A8M6 | NP_416511.4 | b2007 (yeeX) | Escherichia coli str. K-12 substr. MG1655 | PRK05423 | 126 | 124 | DUF496 | – | GAP (GTPase activating protein)-like protein | in progress
P46837 | [NAME] | b3407 (yhgF) | Escherichia coli str. K-12 substr. MG1655 | CLSK862831 | 86 | 2070 | – | S1; Tex_N | RNA binding and [NAME] nuclease | in progress
P0AAS7 | NP_415061.2 | b0528 (ybcJ) | Escherichia coli str. K-12 substr. MG1655 | PRK11507 | 63 | 166 | – | – | RNA binding and [NAME] nuclease | in progress
P77328 | NP_415046.4 | b0513 (ybbY) | Escherichia coli str. K-12 substr. MG1655 | PRK11412 | 44 | 99 | – | Xan_ur_permease | Nucleobase permease | in progress
Q46817 | YP_026186.1 | b4464 (ygfQ) | Escherichia coli str. K-12 substr. MG1655 | CLSK870037 | 172 | 1068 | – | Xan_ur_permease | Nucleobase permease | in progress
Q46821 | NP_417364.2 | b2888 (uacT) | Escherichia coli str. K-12 substr. MG1655 | CLSK880522 | 37 | 1272 | – | Xan_ur_permease | Nucleobase permease | in progress
P31440 | NP_418120.2 | b3664 (yicO) | Escherichia coli str. K-12 substr. MG1655 | CLSK2393909 | 30 | 1071 | – | Xan_ur_permease | Nucleobase permease | in progress
P0AF52 | NP_418488.1 | b4064 (yjcD) | Escherichia coli str. K-12 substr. MG1655 | CLSK870037 | 172 | 1070 | – | Xan_ur_permease | Nucleobase permease | in progress
[NAME] | NP_417705.2 | b3238 (yhcN) | Escherichia coli str. K-12 substr. MG1655 | CLSK880623 | 99 | 110 | DUF1471 | – | Periplasmic signal transduction protein | in progress
P0AB40 | NP_415630.1 | b1112 (bhsA) | Escherichia coli str. K-12 substr. MG1655 | CLSK879955 | 59 | 189 | DUF1471 | – | Periplasmic signal transduction protein | in progress
P39297 | NP_418610.4 | b4189 (bsmA) | Escherichia coli str. K-12 substr. MG1655 | CLSK888460 | 80 | 78 | DUF1471 | – | Periplasmic signal transduction protein | in progress
P0AAX6 | NP_415327.2 | b0806 (mcbA) | Escherichia coli str. K-12 substr. MG1655 | CLSK879771 | 39 | 157 | DUF1471 | – | Periplasmic signal transduction protein | in progress
P75694 | NP_414863.1 | b0329 (yahO) | Escherichia coli str. K-12 substr. MG1655 | PRK09929 | 49 | 53 | DUF1471 | – | Periplasmic signal transduction protein | in progress
P0AAX3 | NP_415323.1 | b0802 (ybiJ) | Escherichia coli str. K-12 substr. MG1655 | PRK10259 | 53 | 236 | DUF1471 | – | Periplasmic signal transduction protein | in progress
P76177 | [NAME] | b1604 (ydgH) | Escherichia coli str. K-12 substr. MG1655 | CLSK880144 | 87 | 86 | DUF1471 | – | Periplasmic signal transduction protein | in progress
P0AF82 | NP_418609.4 | b4188 (yjfN) | Escherichia coli str. K-12 substr. MG1655 | CLSK880863 | 37 | 66 | DUF1471 | – | Periplasmic signal transduction protein | in progress
P0AF86 | NP_418620.1 | b4199 (yjfY) | Escherichia coli str. K-12 substr. MG1655 | CLSK880864 | 56 | 60 | DUF1471 | – | Periplasmic signal transduction protein | in progress
P75687 | NP_414837.2 | b0303 (ykgI) | Escherichia coli str. K-12 substr. MG1655 | CLSK879629 | 43 | 42 | DUF1471 | – | Periplasmic signal transduction protein | in progress
P0AGK4 | NP_417647.1 | b3180 (yhbY) | Escherichia coli str. K-12 substr. MG1655 | PRK10343 | 58 | 486 | – | – | rRNA processing | in progress
P0A8X0 | NP_418655.1 | b4234 (yjgA) | Escherichia coli str. K-12 substr. MG1655 | PRK05255 | 246 | 287 | DUF615 | – | rRNA processing | in progress
P0A8H6 | NP_418302.1 | b3866 (yihI) | Escherichia coli str. K-12 substr. MG1655 | PRK05244 | 137 | 101 | DUF414 | – | GAP-like protein | in progress
P25536 | NP_417714.1 | b3248 (yhdE) | Escherichia coli str. K-12 substr. MG1655 | PRK00032 | 119 | 1079 | – | Maf | Maf phosphohydrolase | confirmed
P0A729 | NP_415605.2 | b1087 (yceF) | Escherichia coli str. K-12 substr. MG1655 | [NAME] | 90 | 1053 | – | Maf | Maf phosphohydrolase | in progress
P0ACJ5 | NP_414981.4 | b0447 (ybaO) | Escherichia coli str. K-12 substr. MG1655 | CLSK879671 | 39 | 2500 | – | – | Transcriptional regulator | in progress
A6H1V6 | [NAME] | FP2274 | Flavobacterium psychrophilum JIP02/86 | CLSK976121 | 4 | 894 | – | DNA_methylase | DNA methyltransferase M.FpsJI modifying Cm5CGG | confirmed
A6H1V5 | YP_001297130.1 | FP2273 | Flavobacterium psychrophilum JIP02/86 | CLSK822567 | 7 | 8 | – | – | Restriction endonuclease FpsJI, cleaves C/CGG | confirmed
A8L234 | YP_001509600.1 | Franean1_5336 | Frankia sp. [NAME] | CLSK2307911 | 5 | 11 | – | – | Type IV restriction endonuclease FspEI, recognizes m5CC | confirmed
[NAME] | [NAME] | Hoch_1324 | Haliangium ochraceum DSM 14365 | – | 0 | 108 | – | – | Type IV restriction endonuclease HocMrrP | no activity observed
Q9HNR6 | [NAME] | VNG1980C | Halobacterium sp. NRC-1 | PRK02135 | 53 | 35 | DUF358 | – | Pseudouridine methyltransferase | confirmed
E4NWR5 | YP_004038432.1 | Hbor_37800 | Halogeometricum borinquense DSM 11551 | – | 0 | 114 | – | – | Methyltransferase | no activity observed
O25465 | NP_207566.1 | HP0773 | Helicobacter pylori 26695 | CLSK872443 | 31 | 557 | – | – | 2-nitropropane dioxygenase | in progress
O25838 | NP_208032.1 | HP1240 | Helicobacter pylori 26695 | PRK04056 | 24 | 65 | – | Maf | Maf phosphohydrolase | in progress
O25046 | [NAME] | HP0267 | Helicobacter pylori 26695 | PRK08418 | 25 | 156 | – | Amidohydro_1 | Adenine amidohydrolase | in progress
O25080 | NP_207108.1 | HP0310 | Helicobacter pylori 26695 | CLSK865125 | 45 | 444 | – | – | Acetyl esterase | confirmed
O25492 | NP_207605.1 | HP0812 | Helicobacter pylori 26695 | CLSK872452 | 22 | 89 | DUF185 | DUF185 | Dihydrodipicolinate reductase | in progress
[NAME] | [NAME] | HP0959 | Helicobacter pylori 26695 | CLSK872475 | 8 | 307 | – | NIF3 | GTP cyclohydrolase | in progress
O25483 | NP_207596.1 | HP0803 | Helicobacter pylori 26695 | CLSK496218 | 9 | 36 | – | – | GTP cyclohydrolase | in progress
O25734 | NP_207897.1 | HP1106 | Helicobacter pylori 26695 | CLSK496089 | 16 | 15 | – | – | Adenylosuccinate lyase | in progress
O25199 | NP_207250.1 | HP0452 | Helicobacter pylori 26695 | CLSK2393104 | 2 | 87 | – | – | RNA endonuclease | no activity observed
O25113 | NP_207144.1 | HP0346 | Helicobacter pylori 26695 | CLSK496779 | 6 | 8 | – | – | RNA endonuclease | in progress
O24961 | NP_206949.1 | HP0150 | Helicobacter pylori 26695 | CLSK495886 | 8 | 6 | – | – | Pyruvate dehydrogenase | in progress
O25711 | NP_207870.1 | HP1079 | Helicobacter pylori 26695 | CLSK510467 | 5 | 27 | – | – | ATPase/GTPase linked to cation transport | in progress
O24976 | NP_206969.1 | HP0170 | Helicobacter pylori 26695 | CLSK872291 | 23 | 22 | – | – | Xanthine dehydrogenase | in progress
O25683 | NP_207832.1 | HP1042 | Helicobacter pylori 26695 | CLSK872354 | 25 | 30 | – | DHHA1; DHH | Phosphoesterase | in progress
[NAME] | NP_207827.1 | HP1037 | Helicobacter pylori 26695 | CLSK872355 | 19 | 1777 | – | Creatinase_N; Peptidase_M24 | Aminopeptidase | confirmed
O26093 | NP_208364.1 | HP1573 | Helicobacter pylori 26695 | CLSK872593 | 8 | 1452 | – | TatD_DNase | DNA exonuclease | no activity observed
O25427 | NP_207521.1 | HP0727 | Helicobacter pylori 26695 | CLSK872423 | 25 | 1254 | – | [NAME] | Transcriptional regulator | in progress
A8YW66 | YP_001576608.1 | lhv_0031 | Lactobacillus helveticus DPC 4571 | CLSK903608 | 7 | 11 | – | – | Type IV restriction endonuclease LheDORF31P | no activity observed
Q5ZW53 | YP_095265.1 | lpg1234 | Legionella pneumophila | CLSK2307911 | 5 | 12 | – | – | Type IV restriction endonuclease LpnPI, recognizes Cm5CDG | confirmed
Q6LYT7 | NP_988020.1 | MMP0900 | Methanococcus maripaludis S2 | CLSK876048 | 9 | 253 | – | Rhodanese | 2-selenouridine formation | confirmed
Q6LYT8 | NP_988019.1 | MMP0899 | Methanococcus maripaludis S2 | CLSK876049 | 9 | 74 | – | – | 2-selenouridine formation | confirmed
Q8PYE2 | NP_632944.1 | MM_0920 | Methanosarcina mazei Go1 | CLSK812024 | 5 | 192 | – | NUDIX | NUDIX hydrolase | in progress
B0UKZ8 | YP_001768429.1 | M446_1490 | Methylobacterium sp. 4-46 | CLSK886518 | 5 | 208 | – | – | T•G specific endonuclease | no activity observed
E8N968 | YP_004224384.1 | MTES_1540 | Microbacterium testaceum StLB037 | – | 0 | 5 | – | – | Type IV restriction endonuclease Mte37I, hmC-specific | confirmed
 |  |  | Microcystis aeruginosa |  |  |  |  |  | Restriction endonuclease/methyltransferase | in progress
 |  |  | Microcystis aeruginosa |  |  |  |  |  | Restriction endonuclease/methyltransferase | in progress
P96416 | NP_214747.1 | Rv0233 | Mycobacterium tuberculosis H37Rv | PRK08326 | 42 | 64 | – | Ribonuc_red_sm | Ribonucleotide reductase | in progress
A1TFU0 | YP_956046.1 | Mvan_5269 | Mycobacterium vanbaalenii PYR-1 | CLSK872199 | 39 | 781 | – | – | 2-nitropropane dioxygenase | in progress
A2BPK4 | YP_001008822.1 | A9601_04271 | Prochlorococcus marinus str. AS9601 | CLSK943043 | 4 | 219 | – | – | T•G specific endonuclease | no activity observed
D7GHR1 | YP_003687087.1 | PFREUD_01180 | Propionibacterium freudenreichii | CLSK3091083 | 5 | 5 | – | – | Type IV restriction endonuclease PfrCI, hmC-specific | confirmed
Q15VR7 | YP_661075.1 | Patl_1499 | Pseudoalteromonas atlantica T6c | CLSK903661 | 5 | 5 | – | – | Type IV restriction endonuclease [NAME], hmC-specific | confirmed
Q9I4V0 | NP_249715.1 | PA1024 | Pseudomonas aeruginosa PAO1 | CLSK2297751 | 4 | 525 | – | – | 2-nitropropane dioxygenase | in progress
Q9I5R1 | NP_249351.1 | PA0660 | Pseudomonas aeruginosa PAO1 | CLSK866021 | 14 | 382 | – | – | 2-nitropropane dioxygenase | in progress
Q9HX03 | NP_252713.1 | PA4024 | Pseudomonas aeruginosa PAO1 | CLSK861917 | 228 | 228 | – | – | 2-nitropropane dioxygenase | in progress
Q7LX22 | NP_560564.1 | PAE3199 | Pyrobaculum aerophilum str. IM2 | CLSK811317 | 3 | 1759 | – | HhH-GPD; EndIII_4Fe-2S | T•G specific glycosylase | no activity observed
A3MSP1 | YP_001055124.1 | Pcal_0221 | Pyrobaculum calidifontis [NAME] 11548 | CLSK631190 | 5 | 4 | – | GTP_cyclohydroI | Involved in formation of archaeosine from preQ0 | confirmed
Q471K6 | YP_295771.1 | Reut_A1561 | Ralstonia eutropha JMP134 | CLSK872199 | 39 | 311 | – | – | 2-nitropropane dioxygenase | in progress
Q46R25 | YP_299253.1 | [NAME] | Ralstonia eutropha JMP134 | CLSK878064 | 58 | 254 | – | – | 2-nitropropane dioxygenase | in progress
Q46V67 | [NAME] | Reut_B3609 | Ralstonia eutropha JMP134 | CLSK2309775 | 8 | 910 | – | – | 2-nitropropane dioxygenase | in progress
Q1LJH5 | YP_584970.1 | Rmet_2828 | Ralstonia metallidurans CH34 | CLSK937278 | 3 | 42 | – | – | Type IV restriction endonuclease RmeAORF2828P | no activity observed
Q3J3Q8 | YP_352477.1 | RSP_2415 | Rhodobacter sphaeroides 2.4.1 | CLSK840964 | 5 | 413 | DUF407; DUF404 | – | Glutathionylspermidine synthase | in progress
Q219B4 | [NAME] | RPC_1460 | Rhodopseudomonas palustris BisB18 | CLSK721183 | 2 | 129 | – | – | Restriction endonuclease RpaBI, cleaves CCCGCAG(20/18) | confirmed
Q6N4G1 | NP_948715.1 | RPA3376 | Rhodopseudomonas palustris CGA009 | CLSK359350 | 2 | 89 | – | – | Restriction endonuclease RpaI, cleaves GTYGGAG(11/9) | confirmed
E3H4U6 | YP_003982999.1 | HMPREF0733_10107 | Rothia dentocariosa ATCC 17931 | – | 0 | 99 | – | – | Restriction endonuclease/methyltransferase RdeGBI, recognizes CCGCAG | confirmed
E3H1D0 | YP_003983491.1 | HMPREF0733_10599 | Rothia dentocariosa ATCC 17931 | – | 0 | 30 | – | – | Restriction endonuclease RdeGBIII, cleaves [NAME]) | confirmed
E3H3F9 | YP_003983855.1 | HMPREF0733_10964 | Rothia dentocariosa ATCC 17931 | – | 0 | 103 | – | – | Restriction endonuclease/methyltransferase RdeGBII, recognizes ACCCAG | confirmed
A4F7B2 | YP_001102862.1 | SACE_0591 | Saccharopolyspora erythraea NRRL 2338 | PRK08326 | 42 | 82 | – | Ribonuc_red_sm | Ribonucleotide reductase | in progress
P58627 | [NAME] | STM1189 | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 | [NAME] | 90 | 1064 | – | Maf | Maf phosphohydrolase | in progress
A8H6T6 | YP_001502808.1 | Spea_2956 | Shewanella pealeana ATCC 700345 | CLSK903661 | 5 | 4 | – | – | Type IV restriction endonuclease SpeAI, hmC-specific | confirmed
A8H9C2 | YP_001503694.1 | Spea_3849 | Shewanella pealeana ATCC 700345 | CLSK903608 | 7 | 11 | – | – | Type IV restriction endonuclease SpeAORF3849P | no activity observed
F2F0D5 | – | SSIL_0822 | Solibacillus silvestris StLB046 | – | 0 | 5 | – | – | Type IV restriction endonuclease Ssi46I, hmC-specific | confirmed
D7A4P1 | YP_003692558.1 | Snov_0606 | [NAME] novella DSM 506 | – | 0 | 119 | – | – | Restriction endonuclease Sno506I, recognizes GGCCGAG | confirmed
D1AWC1 | YP_003305474.1 | [NAME] | Streptobacillus moniliformis DSM 12112 | – | 0 | 7 | – | – | Restriction endonuclease [NAME], cleaves C/CGG | confirmed
– | – | Smon_0102 | Streptobacillus moniliformis DSM 12112 | – | 0 | 745 | – | – | DNA methyltransferase M.SmoLIP modifying CCGG | no activity observed
 |  |  | Streptobacillus moniliformis DSM 12112 |  |  |  |  |  | Multisubunit restriction/modification system | in progress
Q981C9 | [NAME] | [NAME] | Sulfolobus solfataricus P2 | CLSK883593 | 11 | 642 | – | – | [NAME] biosynthesis | confirmed
Q30Q89 | YP_394077.1 | Suden_1565 | Sulfurimonas denitrificans DSM 1251 | CLSK918520 | 8 | 963 | – | DNA_methylase | DNA methyltransferase M.SdeAIII, recognizes CCNGG | confirmed
Q30Q91 | YP_394075.1 | Suden_1563 | Sulfurimonas denitrificans DSM 1251 | CLSK942922 | 3 | 2 | – | – | Restriction endonuclease SdeAII, cleaves /CCNGG | confirmed
Q9HJT3 | NP_394339.1 | Ta0880 | Thermoplasma acidophilum DSM 1728 | CLSK227765 | 3 | 188 | – | Pfkb | Ribokinase family sugar kinase | confirmed
B1YBZ5 | YP_001793825.1 | Tneu_0431 | Thermoproteus neutrophilus V24Sta | CLSK811317 | 3 | 1531 | – | HhH-GPD; EndIII_4Fe-2S | T•G specific glycosylase | no activity observed
Q9WYS2 | NP_228251.1 | TM0441 | Thermotoga maritima MSB8 | CLSK795163 | 4 | 16799 | – | adh_short | Short-chain dehydrogenase/reductase | confirmed
Q9WZ12 | [NAME] | TM0542 | Thermotoga maritima MSB8 | CLSK875209 | 6 | 1115 | – | malic; Malic_M | Malate dehydrogenase | confirmed
Q9WYS1 | NP_228250.1 | TM0440 | Thermotoga maritima MSB8 | CLSK875144 | 16 | 15 | – | – | Tagaturonate/fructuronate epimerase | confirmed
Q9X1P2 | NP_229356.1 | TM1556 | Thermotoga maritima MSB8 | PRK14363 | 5 | 1056 | – | Maf | Maf phosphohydrolase | in progress
D1BQQ9 | YP_003311152.1 | Vpar_0184 | Veillonella parvula DSM 2008 | – | 0 | 702 | – | – | Type IV restriction endonuclease Vpa2008ORF184P | no activity observed
Q8D477 | [NAME] | VV2_1434 | Vibrio vulnificus CMCP6 | PRK02135 | 53 | 47 | DUF358 | – | Psi methyltransferase | no activity observed
F0NXA3 | YP_004237455.1 | Weevi_0153 | Weeksella virosa DSM 16922 | – | 0 | 102 | – | – | Restriction endonuclease WviI, cleaves CACRAG(21/19) | confirmed
Q8P4X5 | NP_638923.1 | XCC3577 | [NAME] campestris pv. [NAME]. ATCC 33913 | CLSK903608 | 7 | 11 | – | – | Type IV restriction endonuclease XcaCORF3577P | no activity observed
TOTALS | 140 |  |  |  | 3242 |  | 8 | 28