Spreadsheet: 165b92d6-ca73-4207-8043-d62dff898c1e
Sheet: Sheet1

Unnamed: 0 | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11
Table S3. Candidate regions for recent selection from CHM datasets by iHS test
Chr. | Start | End | Genes in region | Number of core SNPs with p-Value < 0.005 | Maximum median |iHS|a | [NAME] | Maximum |iHS | Peak SNP | Overlap with the Region detected by XDiHHc | HapMap population for which positive selection was reportedd | Test used to identify in previous studyd
6 | 29472930 | 29619195 | GPR53P,[NAME],OR10C1,OR11A1,OR12D1P,OR12D2,OR2H1 | 16 | 4.7519 | 1 | 5.4687 | rs6904456 | *
7 | 49750164 | 50180624 | LOC100128734,LOC100130988,VWC2,ZPBP | 19 | 3.3877 | 12 | 3.7023 | [NAME] | * | ASN | Rsb-AC
5 | 112000094 | 112567854 | APC,DCP2,LOC728217,MCC,REEP5,SRP19,XBPP1,XR_015356.2,ZRSR1 | 75 | 3.3635 | 18 | 4.8022 | rs1363333 | * | ASN, CEU | LRH, Rsb-AC
6 | 31443686 | 31710946 | 3.8-1,AIF1,ATP6V1G2,BAT1,BAT2,HCP5,LOC100129668,LOC100129921,LOC100130756,LST1,LTA,LTB,MCCD1,MICB,NCR3,NFKBIL1,NR_002812.2,NR_002971.1,NR_003065.1,NR_003140.1,PPIAP9,SNORA38,SNORD117,SNORD84,TNF | 25 | 2.9329 | 49 | 4.3411 | rs13215091 | * | ASN | LRH, Rsb-AC
6 | 29757084 | 29823976 | [NAME],RPL23AP1,XR_039877.1 | 17 | 2.9002 | 56 | 3.9208 | rs7741807 | *
9 | 15816730 | 16038844 | C9orf93 | 22 | 2.8357 | 66 | 3.8268 | rs10810521
6 | 33797512 | 33902107 | IHPK3,LEMD2,MLN | 10 | 2.7974 | 69 | 4.1659 | rs943466 | *
6 | 83104741 | 83468325 | TPBG | 23 | 2.774 | 72 | 3.831 | rs9341927 |  | ASN | LRH, Rsb-AC
8 | 31927661 | 32285297 | LOC100127894,NRG1 | 29 | 2.7718 | 74 | 3.9855 | rs12550484 |  | ASN | Rsb-AC
10 | 11116880 | 11259659 | CUGBP2,LOC439950,XR_040718.1 | 19 | 2.7479 | 84 | 4.2786 | rs12248765 |  | YRI | LRH
15 | 84608081 | 84903629 | AGBL1,LOC727915,XR_039951.1 | 33 | 2.721 | 85 | 4.0872 | rs1431242
7 | 53298520 | 53651103 | LOC100129159,RNU1P7 | 18 | 2.7099 | 91 | 3.1961 | rs2330532
10 | 73410619 | 73921144 | ASCC1,C10orf104,CBARA1,CHST3,DDIT4,DNAJB12,SPOCK2 | 27 | 2.6963 | 101 | 4.5709 | rs7090800
15 | 28141595 | 29198135 | ARHGAP11B,CHRFAM7A,FAM7A3,LOC100128435,LOC100129832,LOC100132024,LOC100132031,LOC100132204,LOC100132567,LOC100132726,LOC100132816,LOC100133246,LOC100133333,LOC388104,LOC390561,LOC642397,LOC643699,LOC653073,LOC653075,LOC727880,LOC727909,LOC728388,LOC728424,LOC728498,LOC730909,MIRN211,MTMR10,MTMR15,TRPM1,XR_015162.1,XR_015297.2,XR_016431.2,XR_041689.1 | 32 | 2.69 | 103 | 4.4412 | rs10851487 |  | ASN | XP-EHH
7 | 142046378 | 142750349 | C7orf34,CASP2,CLCN1,EPHB6,GSTK1,KEL,LOC730647,NR_001296.2,NR_002140.1,OR6V1,OR6W1P,OR9A2,OR9P1P,PIP,PRSS1,PRSS2,TAS2R39,TAS2R40,TMEM139,TRB@,TRBC1,TRBC2,TRBD1,TRBD2,TRBJ1-1,TRBJ1-2,TRBJ1-3,TRBJ1-4,TRBJ1-5,TRBJ1-6,TRBJ2-1,TRBJ2-2,TRBJ2-2P,TRBJ2-3,TRBJ2-4,TRBJ2-5,TRBJ2-6,TRBJ2-7,TRBV25-1,TRBV26,TRBV27,TRBV28,TRBV29-1,TRBV30,TRBVA,TRBVB,TRPV5,TRPV6,TRY5,TRY6,TRY7 | 11 | 2.6642 | 125 | 3.8168 | rs6962582 | * | ASN, CEU, YRI | IHS, LRH, Rsb-AC, Rsb-AE
12 | 58359507 | 58538883 | SLC16A7 | 23 | 2.6612 | 132 | 2.8721 | rs2711667 | *
1 | 153134679 | 154401865 | ADAM15,ARHGEF2,ASH1L,C1orf104,C1orf2,CKS1B,CLK2,DAP3,DCST1,DCST2,DPM3,EFNA1,EFNA3,EFNA4,FDPS,[NAME],GBAP,GON4L,HCN3,KIAA0907,KRTCAP2,LENEP,LMNA,LOC100128585,LOC100129268,LOC100129405,LOC100132108,LOC100133278,LOC284620,LOC645676,LOC648822,MAPBPIP,MEX3A,MIRN555,MRPS29P1,MSTO1,MTX1,MTX1P,MUC1,NR_002188.1,NR_002974.1,NR_003005.1,PBXIP1,PKLR,PMVK,POU5F1P4,PYGO2,RAB25,RAG1AP1,RIT1,RUSC1,RXFP4,SCAMP3,SCARNA4,SEMA4A,SHC1,SNORA42,SSR2,SYT11,THBS3,TRIM46,UBQLN4,XR_017656.2,XR_039412.1,XR_039418.1,XR_040469.1,YY1AP1,ZBTB7B | 16 | 2.6448 | 142 | 3.1112 | rs822490 |  | CEU | Rsb-AE
4 | 99816899 | 100644250 | ADH1A,ADH1B,ADH1C,ADH4,ADH5,ADH6,ADH7,BTF3L3,EIF4E,LOC100131750,METAP1,PCNAP1,PCNAP2,TBCAP3 | 39 | 2.5933 | 166 | 3.7952 | rs1373244 |  | ASN | LRH
4 | 122883773 | 123128865 | BBS7,CCNA2,EXOSC9,TMEM155,TRPC3 | 11 | 2.5818 | 177 | 3.8686 | rs6534324
13 | 64673295 | 65065562 | STARP1 | 13 | 2.5804 | 183 | 3.4628 | rs17070716
10 | 94834757 | 95168236 | FER1L3,LOC387703,LOC389997,LOC643863,XR_016730.2,XR_016732.2 | 11 | 2.5489 | 224 | 3.3675 | rs4244304 |  | ASN | IHS
1 | 214301856 | 214718427 | MRPS18BP1,USH2A | 17 | 2.5484 | 227 | 3.1158 | [NAME]
3 | 25673708 | 26394128 | [NAME],TOP2B,VENTXP4,XR_015697.2,XR_016793.2 | 13 | 2.5401 | 242 | 3.9146 | [NAME] |  | ASN, CEU | IHS, Rsb-AC, Rsb-AE
15 | 41183139 | 42029331 | ADAL,CATSPER2,CATSPER2P1,CCNDBP1,CKMT1A,CKMT1B,ELL3,EPB42,FRMD5,HISPPD2A,HYPK,LCMT2,LOC100129392,LOC100129835,LOC100131250,LOC146053,LOC390581,LOC554224,LOC728758,MAP1A,MFAP1,NR_002318.2,NR_003571.1,PDIA3,SERF2,SERINC4,STRC,STRCP,TGM5,TGM7,TMEM62,TP53BP1,TUBGCP4,UBR1,WDR76,XR_017187.2,ZSCAN29 | 30 | 2.5381 | 257 | 3.3604 | rs496584
9 | 125315534 | 125772068 | DENND1A | 25 | 2.5092 | 279 | 3.9603 | rs543070
2 | 17322130 | 17962686 | GEN1,KCNS3,LOC284952,LOC388925,MSGN1,RAD51AP2,SMC6,VSNL1,XR_016133.2 | 19 | 2.4812 | 311 | 3.475 | rs2615048 |  | ASN | Rsb-AC
4 | 144085356 | 144501674 | GAB1,LOC645018,LOC729675,USP38 | 37 | 2.4699 | 315 | 3.2302 | rs4323053 | * | ASN | IHS, LRH
12 | 122926070 | 123174017 | CCDC92,DNAH10,FLJ45278,XR_041543.1,ZNF664 | 11 | 2.4609 | 326 | 2.4609 | rs11057401 | *
4 | 33870248 | 34300068 | LOC727819 | 32 | 2.4533 | 340 | 4.119 | rs998460 |  | ASN, CEU, YRI | IHS, LRH
8 | 68697539 | 68840303 | CPA6 | 12 | 2.4474 | 345 | 4.3412 | rs2623837
5 | 37988716 | 38081927 |  | 18 | 2.447 | 349 | 3.6645 | rs1567327
1 | 65646460 | 65911163 | DNAJC6,LEPR,LEPROT,LOC100128633 | 16 | 2.4453 | 368 | 3.3189 | rs9436746 |  | ASN | LRH
10 | 100873537 | 101029623 | HPSE2 | 3 | 2.4353 | 376 | 3.3874 | rs10883299 | *
10 | 17024588 | 17069941 | CUBN | 10 | 2.4341 | 383 | 3.0092 | rs1707275
3 | 122076151 | 122586192 | STXBP5L | 20 | 2.4301 | 386 | 2.4966 | rs9822141 | *
10 | 3962277 | 4193580 | LOC727894 | 32 | 2.4287 | 393 | 4.1356 | rs2765658
11 | 82877509 | 83001968 | [NAME] | 9 | 2.4199 | 397 | 3.5433 | rs10792688 | * | ASN, CEU | Rsb-AC, Rsb-AE
13 | 33738523 | 33887795 |  | 3 | 2.4129 | 409 | 3.4268 | rs10870673
6 | 18807196 | 19320384 | LOC645157,TRNAQ-CUG,XR_016770.2 | 36 | 2.4099 | 419 | 3.4201 | rs9460306 | * | ASN | LRH, Rsb-AC
11 | 80968833 | 81162644 |  | 4 | 2.4048 | 424 | 3.0513 | rs17142769 |  | ASN | Rsb-CE
4 | 158603317 | 158909796 |  | 13 | 2.3878 | 446 | 2.7334 | rs1907091 |  | ASN | IHS
10 | 113353697 | 113523060 |  | 10 | 2.3806 | 460 | 2.8866 | [NAME] | *
11 | 17882560 | 18130383 | LOC645297,MRGPRX3,SAA3P,SAAL1,SERGEF,TPH1 | 20 | 2.3677 | 483 | 3.5543 | rs2237914
6 | 28141375 | 28321218 | LOC100129195,LOC222699,LOC222701,NR_002936.1,OR1F12P,TRNAS-GCU,[NAME] | 10 | 2.3651 | 484 | 4.529 | rs7757215 | * | CEU | Rsb-AE
4 | 153037972 | 153215732 |  | 17 | 2.3624 | 490 | 3.4007 | rs4696313
6 | 89587114 | 89887093 | CYCSP16,LOC100131124,PNRC1,RNGTT,SRrp35,XR_038480.1 | 5 | 2.3491 | 518 | 3.244 | rs1980986 |  | ASN | Rsb-AC
21 | 37094076 | 37323409 | DPRXP5,DSCR6,HLCS,MRPL20P1 | 9 | 2.3481 | 521 | 2.64 | rs8134067
21 | 29442778 | 29607434 | BACH1,C21orf7 | 10 | 2.3429 | 532 | 3.1835 | [NAME] | *
19 | 19148928 | 19722682 | ATP13A1,CILP2,EDG4,FLJ44968,GATAD2A,[NAME],HAPLN4,KIAA0892,LOC100128429,LOC100130292,LOC100133072,LOC729991,MEF2B,MIRN640,NCAN,NDUFA13,NR2C2AP,PBX4,PHF5CP,RFXANK,SF4,TM6SF2,TSSK6,XR_041229.1,ZNF101,ZNF14 | 12 | 2.3363 | 555 | 3.1171 | rs4808199
9 | 26740804 | 27142308 | C9orf82,IFT74,LRRC19,PLAA,TEK | 13 | 2.3279 | 573 | 4.1709 | rs12684983
6 | 108679188 | 109180409 | FOXO3,LACE1,LOC100130258,LOC100130966,SNX3 | 16 | 2.3205 | 597 | 3.3625 | rs1268167 | *
13 | 103885691 | 103998191 |  | 13 | 2.3123 | 622 | 2.8118 | rs9514269 |  | CEU | Rsb-AE
13 | 82609916 | 83036907 |  | 25 | 2.3065 | 633 | 3.187 | rs1592213 | *
18 | 21882483 | 22336707 | DHFRP1,KCTD1,LOC728592,PSMA8,SS18,TAF4B,XR_015538.2 | 11 | 2.3027 | 637 | 3.1953 | rs8083533 | *
1 | 170906205 | 171276455 | [NAME] | 10 | 2.3022 | 653 | 2.9936 | rs704847
4 | 28235503 | 28413202 |  | 4 | 2.2986 | 661 | 3.1532 | rs1121274
9 | 87119053 | 87225352 |  | 13 | 2.2927 | 670 | 3.2894 | rs1374503
2 | 43774993 | 43985595 | ABCG5,ABCG8,DYNC2LI1,LRPPRC,PLEKHH2 | 14 | 2.2912 | 678 | 3.7684 | rs7570252 |  | ASN | Rsb-AC, Rsb-CE
1 | 4322090 | 4393548 |  | 9 | 2.2866 | 685 | 2.6935 | rs6697594
8 | 138590751 | 138671999 |  | 11 | 2.2843 | 694 | 3.1763 | rs11786786
11 | 32266283 | 32410198 | WT1 | 8 | 2.2828 | 714 | 3.2012 | rs5030277
4 | 168828749 | 169231643 |  | 13 | 2.2731 | 725 | 2.9667 | [NAME]
1 | 75474760 | 75882161 | LOC646417,SLC44A5 | 16 | 2.2713 | 733 | 2.6619 | rs598649 |  | ASN | Rsb-AC, Rsb-CE
2 | 25696756 | 26560146 | ASXL2,C2orf39,DTNB,FAM59B,GPR113,HADHA,HADHB,[NAME],LOC391358,LOC391359,LOC646196,LOC729769,LOC751599,OTOF,PPIL1P1,RAB10,SELI,XR_041889.1 | 20 | 2.268 | 745 | 2.9173 | rs10865402 |  | ASN | Rsb-AC
2 | 125888500 | 126110004 |  | 7 | 2.2669 | 749 | 3.6285 | rs9308661 |  | ASN | Rsb-AC
15 | 53102462 | 53376504 | C15orf15,RAB27A | 13 | 2.2592 | 798 | 2.6167 | [NAME] |  | YRI | LRH
7 | 8280496 | 8476937 | NXPH1 | 11 | 2.2466 | 847 | 2.9781 | rs42949
2 | 12700041 | 12887438 | TRIB2 | 17 | 2.2458 | 854 | 3.1509 | rs2042566
8 | 10619507 | 10743821 | PINX1,SOX7 | 10 | 2.2407 | 862 | 3.6938 | rs4840517
7 | 139814627 | 140328542 | ADCK2,BRAF,DENND2A,MKRN1,NDUFB2 | 6 | 2.2371 | 871 | 4.2233 | rs2293177
3 | 134105412 | 134167861 |  | 2 | 2.2296 | 896 | 3.0151 | rs4854669
11 | 82641607 | 82871413 | CCDC90B,CYCSP28,DLG2 | 4 | 2.229 | 898 | 3.1187 | rs2510475 | * | ASN, CEU | Rsb-AC, Rsb-AE
2 | 21536938 | 21966561 | [NAME] | 7 | 2.2197 | 914 | 3.575 | rs2161900 |  | ASN, YRI | IHS
16 | 76183248 | 76228682 |  | 1 | 2.2128 | 944 | 3.1476 | rs12928238
1 | 50488854 | 51417290 | C1orf185,CDKN2C,DMRTA2,FAF1,LOC100129919,LOC343184,LOC391039,LOC729168,MRPS6P2,XR_016832.1,XR_017560.2 | 14 | 2.2118 | 947 | 2.7584 | rs11205760 |  | ASN | Rsb-AC
11 | 119651570 | 119762705 | ARHGEF12,LOC649133,POU2F3,TMEM136 | 5 | 2.2118 | 947 | 3.8948 | rs4142654 |  | CEU | LRH
7 | 126727857 | 126962472 | ZNF800 | 22 | 2.2086 | 980 | 2.9561 | rs11975300 |  | ASN
10 | 121717570 | 121817505 | LOC651144 | 9 | 2.2037 | 998 | 3.2325 | rs10886561
6 | 83739609 | 83995702 | DOPEY1,ME1,PGM3,RWDD2A,UBE2CBP | 8 | 2.202 | 1002 | 3.1799 | rs686786 | * | ASN | LRH
4 | 41362805 | 41921681 | CCDC4,LIMCH1,LOC100128654,LOC100133310,OR5M14P,PHOX2B,SLC30A9,TMEM33,WDR21B | 12 | 2.1984 | 1020 | 3.8656 | rs2343617 |  | ASN | IHS, Rsb-AC, XP-EHH
6 | 48964829 | 49271394 |  | 9 | 2.1915 | 1043 | 3.0303 | rs6931955
16 | 71102326 | 71413345 | [NAME] | 10 | 2.1886 | 1052 | 3.5052 | rs2914781 | *
2 | 212756061 | 212979704 | ERBB4 | 13 | 2.1835 | 1062 | 2.9182 | rs1948877 |  | ASN | Rsb-AC
9 | 126675534 | 126955768 | ARPC5L,C9orf126,GOLGA1,PPP6C | 4 | 2.1798 | 1077 | 2.9389 | rs6478690 |  | CEU | Rsb-AE
15 | 52579720 | 52807566 | UNC13C | 19 | 2.1796 | 1083 | 3.4256 | rs1074876
6 | 80085313 | 80197796 | LOC100131959 | 13 | 2.1795 | 1086 | 2.4763 | rs17799408 |  | ASN | Rsb-AC
1 | 200518436 | 200778869 | CYCSP4,LGR6,LOC100128298,PPP1R12B,UBE2T | 2 | 2.1764 | 1098 | 2.8891 | [NAME]
8 | 71167651 | 71507138 | BTF3L2,H2AFZP2,LOC100128955,NCOA2 | 4 | 2.1708 | 1125 | 3.0848 | rs16937002
2 | 127650168 | 127971354 | CYP27C1,ERCC3,IWS1,LOC100130102,LOC100131492,MAP3K2,PROC,XR_039053.1 | 9 | 2.1685 | 1135 | 3.1401 | rs6731176 |  | ASN | Rsb-AC
16 | 74049743 | 74471997 | ADAT1,CHST5,CHST6,FLJ22167,GABARAPL2,KARS,LOC124496,LOC645799,TERF2IP,TMEM170,XR_038199.1 | 5 | 2.1678 | 1141 | 4.4579 | rs2289063 |  | ASN, YRI | IHS, LRH
3 | 80553990 | 80775368 |  | 23 | 2.1668 | 1149 | 2.2269 | rs7626516 | *
3 | 117342919 | 117522532 | LSAMP | 3 | 2.1655 | 1166 | 3.3126 | rs4296590 |  | ASN, CEU | Rsb-AC, Rsb-AE
1 | 174564800 | 175079519 | LOC100130637,LOC730167,PAPPA2 | 8 | 2.1639 | 1172 | 3.5884 | rs1086519
1 | 10077870 | 10486268 | APITD1,CORT,[NAME],KIF1B,PEX14,PGD,UBE4B | 14 | 2.1629 | 1186 | 3.2164 | rs1555849
13 | 73576512 | 73752182 | KLF12 | 4 | 2.1547 | 1224 | 3.0573 | rs1337043
11 | 24966286 | 25138024 | LOC100130747,LUZP2 | 15 | 2.1534 | 1225 | 3.3801 | rs2403995 |  | ASN | Rsb-AC, Rsb-CE
10 | 64324208 | 64425615 |  | 16 | 2.1533 | 1226 | 2.6373 | rs1571918 | *
14 | 95448001 | 95560098 | LOC730125 | 4 | 2.1437 | 1272 | 3.1402 | rs2369415
12 | 27518427 | 27614469 | LOC341346,PPFIBP1 | 2 | 2.1376 | 1295 | 3.1626 | rs10506022
3 | 45660752 | 45771955 | LIMD1,LOC644714,SACM1L,SLC6A20,TRR | 5 | 2.1345 | 1315 | 2.8643 | rs2742395
7 | 141760736 | 141911661 | TRB@,TRBV10-1,TRBV10-2,TRBV11-1,TRBV11-2,TRBV12-1,TRBV12-2,TRBV5-4,TRBV5-5,TRBV5-6,TRBV5-7,TRBV5-8,TRBV6-5,TRBV6-6,TRBV6-7,TRBV6-8,TRBV6-9,TRBV7-4,TRBV7-5,TRBV7-6,TRBV7-7,TRBV7-8,TRBV9 | 5 | 2.1334 | 1322 | 3.3708 | rs4726527 |  | ASN, YRI | IHS, LRH, Rsb-AC
6 | 47707937 | 47837009 | [NAME] | 10 | 2.1317 | 1332 | 3.5946 | rs16876369 |  | ASN | LRH
7 | 111585167 | 111891750 | DOCK4,IFRD1,ZNF277 | 8 | 2.1307 | 1342 | 3.6027 | rs7789649 |  | ASN | Rsb-AC
4 | 141607698 | 141746434 | ELMOD2,LOC152586,UCP1 | 4 | 2.129 | 1362 | 3.3302 | rs6853092
21 | 16125656 | 16485140 | C21orf34,USP25,VDAC2P | 10 | 2.1176 | 1409 | 2.5093 | rs420571 |  | ASN, CEU | Rsb-AC, Rsb-AE
2 | 154290496 | 154440383 | GALNT13,LOC100131207 | 2 | 2.1148 | 1423 | 3.0795 | rs2028509
3 | 62092225 | 62256476 | PTPRG | 1 | 2.1077 | 1449 | 3.126 | rs2242352
6 | 32516820 | 32734250 | HLA-DQA1,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-DRB6,HLA-DRB9,NR_001298.1 | 6 | 2.107 | 1450 | 3.9629 | rs9270986 | *
2 | 218809114 | 219141841 | AAMP,ARPC2,C2orf62,CTDSP1,GPBAR1,LOC646532,MIRN26B,PNKD,SLC11A1,TMBIM1,TRNAY-AUA,USP37,VIL1 | 3 | 2.1021 | 1472 | 3.0492 | rs13430006
18 | 37104420 | 37314469 | KC6,NR_002838.1 | 5 | 2.101 | 1476 | 2.9732 | rs2440455
17 | 45739500 | 46091402 | ABCC3,ACSF2,CACNA1G,CHAD,EME1,EPN3,LOC100130580,LOC100132388,LRRC59,MRPL27,MRPS21P9,MYCBPAP,RSAD1,SPATA20,XYLT2 | 6 | 2.0996 | 1482 | 3.007 | rs9890721
1 | 188047656 | 188145217 |  | 1 | 2.0945 | 1529 | 2.711 | rs10920080
2 | 102482655 | 102578208 | SLC9A4 | 5 | 2.0937 | 1530 | 2.8069 | rs6761871 | *
Medians of the moving windows that consist of 20 contiguous SNPs were calculated. The regions were defined by merging overlapping significant windows having p < 0.005 of median |iHS|.
aMedian of |iHS| for each window were used to rank the windows.
bThe regions were ordered by the ranks of windows that had the highest rank within the regions.
cStatistically significant overlapping of the top 20 regions with Table S7 was confirmed by the bootstrap test (P < 0.0001).
dLists of regions for positive selection are obtained by previous reports (Frazer, et [NAME]. [1], [NAME], et [NAME]. [16], and [NAME], et [NAME]. [18]).