Spreadsheet: 1d2c3881-39ca-4881-ac8d-2cd788eb9665
Sheet: Sheet1

§S11 Genes Implicated In Sexual Reproduction in Fungi | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5
Table §S11.1 provides a list of 215 genes that are implicated in sexual reproduction in fungi.  In all cases, if a gene is present in A. nidulans, it is present in all three fungi.
Gene |  | Function | A.nidulans | A.fumigatus | A.oryzae
Mating Process
MAT1 (matB) |  | Mating-type (alpha-box domain transcriptional activator) | AN2755.2 | - | 20164.m00251*
MAT2 (matA) |  | Mating-type (HMG-box transcriptional activator) | AN4734.2 | 59.m09249 | -
[NAME] (MFa1, MFa2) |  | Pheromone precursor (alpha-factor like) | AN5791.2 | 69.m14805 | 20086.m00080*
ppgB (MFa1, MFa2) |  | Pheromone precursor (for a-factor like) | Ambiguous | Ambiguous | Ambiguous
(KEX1) |  | Carboxypeptidase alpha-factor processing | AN1384.2 | 70.m14837 | 20080.m00038*
[NAME] ([NAME]) |  | Endoprotease for alpha-factor processing | AN3583.2 | 58.m07381 | 20179.m00626
(STE13) |  | Dipeptidyl aminopeptidase alpha-factor processing | AN2946.2 | 59.m09093 | 20174.m00466*
(STE23) |  | Dipeptidyl aminopeptidase for a-factor processing | AN8044.2* | 53.m03900* | 20129.m0021*
(RCE1) |  | CAAX prenyl protease a-factor C-terminal processing | AN6528.2 | 62.m03116 | 20107.m00091*
(STE24) |  | CAAX prenyl protease | Yes** | 58.m07859 | 20142.m00264*
(RAM1/STE16) |  | CAAX-farnesyltransferase beta subunit; a-factor modification | AN2002.2 | 58.m07610 | 20138.m00208*
([NAME]) |  | CAAX-farnesyltransferase alpha subunit | AN3867.2 | 58.m07839 | 20142.m00239*
(STE14) |  | CAAX-prenyl cysteine carboxymethyltransferase | AN6162.2 | 72.m19009 | 20177.m00422*
atrD (STE6) |  | ATP-dependent efflux pump for a-factor like pheromone | AN2300.2 | 58.m08958 | 20136.m00137*
[NAME]
preB (STE 2) |  | Pheromone Receptor  (for alpha-factor like pheromone) | AN2520.2 | 59.m08468 | 20123.m00180*
preA (STE 3) |  | Pheromone Receptor  (for a-factor like pheromone) | AN7743.2 | 71.m15771 | 20162.m00356*
fadA ([NAME]) |  | Alpha-subunit G protein | AN0651.2 | 70.m15256 | 20180.m01174
sfaD (STE 4) |  | Beta-subunit G protein | [NAME] | 71.m15359 | 20148.m002796*
(STE5) |  | Scaffold protein | - | - | -
(STE18) |  | Gamma-subunit G protein | AN2742.2 * | 54.m06689 | 20175.m00541*
(STE20) |  | Serine/threonine protein kinase MKKKK | AN2067.2* | 57.m05766 | 20178.m00629*
[NAME] (STE11) |  | Serine/threonine protein kinase MKKK | AN2269.2 | 71.m15914 | 20132.m00123*
(STE7) |  | Serine/threonine protein kinase MKK | AN3422.2* | 59.m09275 | 20164.m00222*
mpkB (FUS3) |  | Mitogen-activated protein kinase | AN3719.2 | 69.m15727 | 20178.m00764*
steA (Ste12) |  | Transcriptional Activator. Homeodomain DNA binding | AN2290.2 | 71.m15938* | 20132.m00151*
(FAR1) |  | Cell cycle arrest in G1/various other roles | - | - | -
(STE50) |  | Pheromone adaptation feedback response | AN7252.2 * | 72.m19797 | 20134.m00115*
(DIG1/RST1) |  | Transcription factor, interacts ste12 pheromone response | - | - | -
(DIG2/RST2) |  | Transcription factor, interacts ste12 pheromone response | - | - | -
Fruiting Body Development
veA |  | Velvet activator induces sexual reproduction A.nidulans | AN1052.2 | 70.m15191* | 20173.m00346*
NsdD |  | GATA-transcription factor | AN3152.2 | 59.m08512* | 20010.m00003*
CsnD |  | Signalosome subunit 4, regulation of sexual development | AN1539.2 | 55.m03058* | 20171.m00527*
CsnE |  | Signalosome subunit 5, regulation of sexual development | AN2129.2 | 72.m19712* | 20115.m00100*
rosA |  | Binuclear zinc transcription factor | AN5170.2 | 69.m14866 | 20084.m00028
mutA |  | [NAME], cell wall turnover during sexual development | AN7349.2 | 57.m05694* | 20150.m00367*
stuA |  | APSES-transcription factor | AN5836.2 | 72.m19916* | 20177.m00377*
medA |  | Transcription factor | AN6230.2 | 72.m19977* | 20141.m00193*
prot1†† |  | Cys6-Zn2 transcriptional activator | AN1848.2* | 58.m07662* | 20129.m00151*
Nc mat A-2 |  | mating type  TF; conserved amphipathic helix | No | No | No
Nc mat A-3 |  | mating type HMG box TF | No | No | No
Nc asd-1 |  | ascus development; rhamnogalacuronase B | AN7135.2 | 89.m02015 | 20153.m00219
Nc asd-4 |  | ascus development; GATA-Zn finger transcription factor | areB | 72.m19434 | 20141.m00163
Nc mei-3 (Sc RAD52) |  | meiosis defective; | uvsC | uvsC | uvsC
Um rum1 |  | repressor of b mating type regulated genes | AN8211.2 | 53.m03763 | 20147.m00252
Um umc1 |  | MADS-box TF, modulator of pheromone-inducible gene expression | [NAME] | 62.m03394 | 20152.m00250
Pa cro1 (Sc SHE4) |  | regulator of myosin function;required for syncytial to cellular transition | AN0135.2 | 71.m15419 | 20158.m00313
Budding and Fisson Yeast Genes involved in Mating, Karyogamy and Meiosis
Sc BIM1 |  | microtubule-binding protein | AN2862.2 | 59.m08708 | 20175.m00472
Sc BNI1 |  | formin | AN6523.2 | 62.m03112 | 20107.m00085
Sc CDC31 |  | spindle pole body component | AN5618.2* | 58.m07543* | 20138.m00126*
Sc CSM1 |  | mediates accurate chromosome segregation during Meiosis I | No | No | No
Sc CSM3 |  | mediates accurate chromosome segregation during meiosis | No | No | No
Sc DIT1 |  | sporulation-specific enzyme required for spore wall maturation | AN2705.2 | 67.m02885 | 20137.m00125
Sc HO |  | endonuclease, mating type switching | No | No | No
Sc IDS2 |  | modulator of Ime2 activity | No | No | No
Sc IME1 |  | master transcriptional regulator of meiosis | No | No | No
Sc IME2 |  | inducer of meiosis, S/T kinase | AN6243.2 | 72.m19414 | 20141.m00207
Sc [NAME] |  | mRNA N6-adenosine methyltransferase, IME1 regulation | No | No | No
Sc KAR1 |  | required for karyogamy | No | No | No
Sc KAR3 |  | kinesin-like motor required for karyogamy | AN6340.2 | 72.m19518 | 20135.m00123
Sc KAR4 |  | TF required for mating and meiosis | No | No | No
Sc KAR5 |  | nuclear membrane fusion during karyogamy | ambiguous | ambiguous | No
[NAME] |  | cytoplasmic microtubule orientation during karyogamy | No | No | No
Sc MUM2 |  | essential for meiotic DNA replication | No | No | No
Sc MUS81 |  | Holliday junction resolvase | AN3118.2 | 59.m08619 | 20140.m00135
Sc NAM8/MRE2 |  | RNA binding protein required for meiotic recombination | AN9090.2 | 66.m04770 | 20169.m00407
Sc NDT80 |  | meiosis-specific transcriptional activator | AN6015.2* | 72.m19128* | 20177.m00637*
Sc REC102 |  | chromosome synapsis during meiotic recombination | No | No | No
Sc RIM4 |  | RNA-binding protein, early and middle sporulation gene expression | No | No | No
Sc RME1 |  | Zn finger transcriptonal repressor of IME1 | No | No | No
Sc STE6 |  | ABC transporter required fo a-factor transport | AN2300.2 | 58.m08958 | 20136.m00137
Sc SPO1 |  | meiosis-specific phospholipase B | No | No | No
Sc SPO11 |  | required for synaptonemal complex formation | AN8259.2 | 53.m03702 | 20147.m00194
Sc SPO13 |  | meiosis specific protein required for Meiosis I and II | No | No | No
Sc SST2 |  | RGS protein, regulates desensitization to alpha-factor | flbA | 72.m19237 | 20082.m00044
Sc SPO22 |  | meiosis-specific phospholipase A2 | No | No | No
Sc SUM1 |  | transcriptional repressor of middle sporulation-specific genes | No | No | No
Sc UME3/SSN8 |  | C-type cyclin | AN2172.2 | 72.m19668 | 20180.m00841
Sc UME6 |  | [NAME] finger regulator of early meiotic genes | No | No | No
Sp atf21 |  | bZip TF, involved in regulation of meiosis | AN6849.2* | 59.m09396* | 20175.m00406*
Sp bgs1 |  | 1,3-beta-glucan synthase subunit, [NAME] target gene | AN3729.2 | 69.m15386 | 20179.m00743
Sp byr1 |  | homologue of Sc STE7
Sp byr2 |  | homolouge of Sc STE11
Sp dhc1 |  | dynein heavy chain, homologue of Sc [NAME] | nudA | 71.m15397 | 10004.m0006
Sp fus1 |  | homologue of Sc BNI1
Sp gpa1 |  | GTP binding (alpha-1 subunit) involved in conjugation | AN3090.2 | 59.m08656 | 20171.m00394
Sp hsk1 |  | homologue of [NAME], Dbf4-dependent kinase | AN3450.2 | 59.m09313 | 20102.m00075
Sp isp5 |  | amino acid permease involved in sexual differentiation | AN5678.2 | 65.m07404 | 20146.m00246
Sp isp6 |  | serine protease involved in sexual differentiation | AN0238.2 | 71.m15644 | 20121.m00147
Sp lid2 |  | homologue of Um rum1, Sc ECM5
Sp ume3 |  | homologue of Sc UME3
Sp mam1 |  | abc transporter for m-factor pheromone, homologue of Sc STE6
Sp mam2 |  | pheromone p-factor receptor,  homologue of Sc STE2
Sp mam4 |  | M-factor farnesyl cysteine carboxyl methyltransferase | AN6162.2 | 72.m19009 | 20177.m00422
Sp map1 |  | MADS-box domain TF, pheromone receptor activator | AN8676.2* | 62.m03394* | 20152.m00250*
Sp map2 |  | P-factor pheromone | No | No | No
Sp map3 |  | pheromone M-factor receptor, homologue of Sc STE3
Sp mat1-Mc |  | mating-type M-specific polypeptide Mc, HMG-box TF | AN1962.2* | 58.m09001* | 20138.m00150*
Sp mat1-Mi |  | mating-type M-specific polypeptide Mi | No | No | No
Sp mat1-Pc |  | mating-type P-specific polypeptide Pc, HMG-box TF | No | No | No
Sp mat1-Pi |  | mating-type P-specific polypeptide Pi, homeodomain TF | No | No | No
Sp mde3 |  | homologue of Sc IME2, Sp Mei4 target gene | AN6243.2 | 72.m19414 | 20141.m00207
Sp [NAME] |  | kelch repeat protein, [NAME] target gene | No | No | No
Sp mde6 |  | ketch repeat protein, [NAME] target gene | No | No | No
Sp mde7 |  | RNA-binding protein involved in meiosis, [NAME] target | AN7700.2 | 71.m15729 | 20162.m00295
Sp mfm1,mfm2,mfm3 |  | M-factor pheromone precursor | No | No | No
Sp mei2 |  | RNA-binding protein involved in meiosis | AN6494.2* | 62.m03081* | 20059.m00031*
Sp [NAME] |  | meiosis inducing protein, inactivates Sp Ran1 | No | No | No
Sp mei4 |  | fork head domain TF, meiotic regulator | AN8858.2* | 71.m15996* | 20108.m00079*
Sp mes1 |  | meiosis II protein, [NAME] target gene | No | No | No
Sp meu1 |  | Sp Mei4 target gene | apsB | 62.m03168 | 20174.m00436
Sp meu14 |  | involved in Meiosis II nuclear division, [NAME] target gene | AN3931.2 | 69.m14916 | 20174.m00532
Sp mus81 |  | homologue of Sc MUS81
Sp pkl1 |  | homologue of Sc KAR3
Sp rad22 |  | DNA repair protein | radC | 58.m08972 | 20110.m00135
Sp ran1/pat1 |  | serine/threonine protein kinase, negative regulator of meiosis | AN4935.2 | 59.m08839 | 20175.m00321
Sp rec6 |  | meiotic recombination protein | No | No | No
Sp rec8 |  | cohesin complex (meiotic), homologue of Sc REC8 | No | No | No
Sp rec10 |  | sister chromatid cohesion | No | No | No
Sp rec11 |  | sister chromatid cohesion | No | No | No
Sp rec12 |  | homologue of Sc SPO11
Sp rec15 |  | meiotic recombination protein | No | No | No
Sp rem1 |  | meiotic B-type cyclin | AN2137.2 | 72.m19703 | 20180.m00780
Sp rep1 |  | regulator of pre-meiotic DNA replication | No | No | No
Sp rgs1 |  | homologue of Sc SST2
Sp rhp51 |  | homologue of [NAME], [NAME] mei-3 | uvsC | uvsC | uvsC
Sp spk1 |  | homologue of Sc FUS3 | mpkB | 69.m15727 | 20178.m00764
Sp spo6 |  | homologue of Sc DBF4, required for orign of replication firing | nimO | 69.m15647 | 20161.m00192
Sp ssm4 |  | [NAME], homologue of Sc NIP100 | AN6323.2 | 72.m19441 | 20141.m00154
Sp ste4 |  | SAM domain, similar to Sc STE50 | AN7252.2 | 72.m19797 | 20134.m00115
Sp ste6 |  | GEF involved in conjugation; related to Sc CDC25 | AN2130.2 | 72.m19711 | 20115.m00099
Sp ste7 |  | meiotic suppressor protein | No | No | No
Sp ste11 |  | HMG-box TF, target of pheromone signaling | AN3667.2* | 58.m07428* | 20179.m00464*
Sp spn5 |  | septin, Sp Mei4 target gene | sepB | 65.m07502 | 20176.m00407
Sp spn7 |  | septin, Sp Mei4 target gene | AN4667.2 | 71.m15708 | 20176.m00407
[NAME] |  | serine carboxypeptidase, degrades extracellular P-factor | AN2555.2 | 57.m05650 | 20156.m00343
Sp tht1 |  | homologue of Sc KAR5
Core Meiotic Transcriptome Conserved in S. cerevisiae and S. pombe
Anaphase-promoting complex
[NAME] nuc2 |  | APC component | bimA | 72.m19026 | 20177.m00440
Sc APC4/ Sp cut20 |  | APC component | AN0905.2 | 70.m15514 | ambiguous
Sc CDC16/ Sp cut9 |  | APC component | AN8002.2 | 53.m03844 | 20159.m00191
Sc APC1/ Sp cut4 |  | APC component | AN2772.2 | 59.m09271 | 20164.m00226
Sc APC5/ Sp apc5 |  | APC component | AN4735.2 | 59.m09246 | 20164.m00254
Sc CDC23/ Sp cut23 |  | APC component | AN8013.2 | 53.m03861 | 20159.m00208
Sc CDC26/ Sp hcn1 |  | APC component | No | No | No
Sc HCT1/ Sp ste9 |  | APC regulator | AN2965.2 | 59.m09050 | 20174.m00432
Sc CDC20/ Sp mfr1 |  | APC regulator | AN2965.2 | 59.m09050 | 20174.m00432
[NAME] |  | APC regulator | AN0814.2 | 70.m15414 | 20125.m00181
Septins
Sc CDC10/ Sp spn2 |  | [NAME] | AN1394.2 | 70.m14828 | 20070.m00026
Sc CDC3/ Sp spn5 |  | [NAME] | sepB | 65.m07502 | 20176.m00407
Sc SPR3/ Sp spn6 |  | sporulation regulated septin | AN8182.2 | 53.m03797 | 20147.m00293
Sc SPR28/ Sp spn7 |  | sporulation regulated septin | AN4667.2 | 71.m15708 | 20148.m00144
Cell cycle regulators
Sc [NAME] clp1 |  | protein phosphatase | AN5057.2 | 59.m08669 | 20175.m00513
Sc CDC5/ Sp plo1 |  | [NAME] | AN1560.2 | 55.m03076 | 20176.m00605
Sc CLB1/ Sp cig2 |  | B-type cyclin | nimE | 58.m07451 | 20165.m00281
Sc CLB3/ Sp cdc13 |  | B-type cyclin | AN2137.2 | 72.m19703 | 20180.m00780
Sc CLB4/ Sp cig1 |  | B-type cyclin
Sc CLB5 |  | B-type cyclin
Sc CLB6 |  | B-type cyclin
Recombination/chromosome cohesion
Sc REC114/ Sp rec7 |  | meiotic recombination protein | No | No | No
Sc DMC1/ Sp dmc1 |  | DNA-binding helix-hairpin-helix protein, DNA strand exchange | AN9092.2 | 66.m04768 | 20169.m00401
Sc MND1/ Sp mcp7 |  | recombinatino and meioic nuclear division, interacts with Hop2 | AN1843.2 | 58.m07668 | 20129.m00169
Sc HOP2/ Sp meu13 |  | prevents synapsis between nonhomologous chromosomes | No | No | No
Sc SMC3/ Sp smc3 |  | cohesin | AN6364.2 | 72.m19496 | 20116.m00127
Sc REC8/ Sp rec8 |  | cohesin complex (meiotic) | No | No | No
Chromosome segregation
Sc STU1/ Sp dis1 |  | spindle pole body component | AN5521.2 | 69.m15719 | 20178.m00784
Sc TID3/ Sp ncd10 |  | chromosome segregation, kinetochore-associated Ndc80 complex | AN4969.2 | 59.m08873 | 20125.m00127
Sc UBC11/ Sp ubc11 |  | ubiquitin-conjugating enzyme, chromosome segregation in Sp | AN5495.2 | 69.m15458 | 20178.m00805
DNA repair
Sc RAD23/ Sp rhp23 |  | DNA excision-repair, NEF2 subunit | AN2304.2 | 71.m15953 | 20108.m00125
Sc EXO1/ [NAME] |  | DNA repair, recombination | AN3035.2 | 59.m08982 | 20174.m00347
Sc HRR25/ Sp hhp1 |  | casein kinase involved in DNA repair and chromsome segregation | AN4563.2 | 57.m05554 | 20158.m00387
Other genes in the conserved meiotic core program
Sc HUL4/ SPBP87.27 |  | hect domain E3 ubiquitin-protein ligase | AN0444.2 | 54.m06635 | 20175.m00618
Sc LEE1/ Sp scp3 |  | Zn finger transcription factor, unknown function | AN3447.2 | 59.m09478 | 20102.m00073
[NAME] |  | P-type ATPase sodium pump | [NAME], | 62.m03239, | 20132.m00104,
 |  |  | AN1628.2 | 58.m07687 | 20136.m00211
Sc PMC1/ SPBC839.06 |  | vacuolar ATPase Ca2+  pump | AN1189.2 | 70.m15033 | 20168.m00440
Sc CMK2/ Sp cmk1 |  | calmodulin-dependent protein kinase | AN3065.2, | 59.m08933, | 20174.m00277,
 |  |  | AN2412.2 | [NAME] | 20073.m00030
Sc CHS1/ Sp chs1 |  | chitin synthase,  pheromone inducible | AN4566.2 | 57.m05488 | 20153.m00320
Sc ISA1/ SPCC645.03C |  | mitochondrial matrix protein, iron metabolism | AN1974.2 | 58.m07579 | 20138.m00166
Sc HTZ1/ Sp pht1 |  | histone H2AZ varient | AN8039.2 | 53.m03907 | 20167.m00250
Sc AUT7/ SPBP8B7.24C |  | required for autophagic vesicle delivery to vacuole in Sc | AN5131.2 | 54.m06897 | 20128.m00130
Sc BAG7/ SPBC557.01 |  | Rho-GAP | AN7650.2 | 57.m05408 | 20105.m00070
Sc ROM2/ SPAC1006.06 |  | Rho-GEF | [NAME] | 71.m15707 | 10080.m00170
Sc RAS2/ Sp ras1 |  | [NAME] | AN0182.2 | 71.m16065 | 20158.m00254
Sc GNA1/ Sp gna1 |  | glucosamine acetyl transferase involved in cell cycle progression | AN8706.2 | 62.m03363 | 20152.m00287
Sc SGA1/ Sp meu17 |  | sporulation-specific glucosamylase, [NAME] target gene | AN8904.2 | 57.m05372 | 20130.m00115,
 |  |  |  |  | 20178.m00683
Sc CLG1/ SPBC1D7.03 |  | cyclin-like protein interacts with Sc Pho85 | AN4984.2 | 59.m08886 | 20125.m00144
Sc CYB2/ SPAB1A11.03 |  | cytochrome-c oxidoreductase | AN3901.2 | 89.m01949 | 20115.m00086
Sc ECM4/ SPCC1281.07C |  | glutathione-S-transferase domain, unknown function | AN5831.2 | 72.m19666 | 20097.m00066
Sc TOS7/ SPCC1739.10 |  | unknown function in yeasts, putative membrane component of | palI | 59.m09122 | 20164.m00305
 |  | signal transduction pathways for pH regulation in A. nidulans
Sc ARN2/ SPCC61.01C |  | ARN family of transporters for siderophore-iron chelates | AN5378.2 | 65.m07225 | 20176.m00502
Sc GTT1/ SPAC688.04C |  | ER associated glutathione S-transferase | AN0629.2 | 70.m15652 | 20155.m00295
Sc RIB5/ SPCC1450.13C |  | riboflavin synthase, alpha subunit | AN4231.2 | 54.m06785 | 20071.m00045
Sc CHO1/ SPCC1442.12 |  | phosphatidylserine synthase | AN5661.2 | 58.m08891 | 20179.m00714
Sc XKS1/ SPCPJ732.02C |  | [NAME] | AN8790.2 | 71.m15584 | 20113.m00155
Sc PCT1/ [NAME] |  | CTP:phosphocholine cytidylyltransferase | AN1357.2 | 70.m14873 | 20074.m00033
Sc ELC1/ SPBC1861.07 |  | transcription elongation factor | No | 69.m15210 | 20101.m00073
Sc SYF2/ SPBC3E7.13C |  | splicesome component | AN1861.2 | 58.m07654 | 20129.m00143
[NAME] |  | phosphoglucomutase | AN2867.2 | 59.m08711 | 20175.m00469
Sc RKI1/ Sp ppi |  | ribose-5-phosphate isomerase | AN2440.2 | 69.m15218 | 20101.m00084
Sc SUR4/ SPAC1B2.03C |  | long chain fatty acid elongation enzyme | AN8117.2 | 53.m03827 | 20159.m00172
Sc PIB1/ SPBC36B7.05C |  | RING-type ubiquitin ligase, FYVE finger domain | AN0627.2* | 70.m15658* | 20174.m00539*,
 |  |  |  |  | 20093.m00096*
Sc PIN3/ Sp csh3 |  | SH3-domain protein | AN2995.2 | 59.m09437 | 20174.m00392
Sc SSO2/ Sp sso1 |  | syntaxin | AN3416.2 | 66.m04618 | 20041.m00017
Sc FBP1/ Sp fbp1 |  | fructose-1,6-biphosphatase | AN5604.2 | 58.m07528 | 20138.m00109
Sc GLG1/ SPBC4C3.08 |  | self-glucosylating initiator of glycogen synthesis | AN4082.2 | 54.m06723 | No
Sc ARE2/ SPAC13G7.05 |  | acyl-CoA:sterol acyltransferase | AN4208.2 | 54.m06767 | 20068.m00041
Sc GDI1/ Sp gdi1 |  | secretory pathway regulator | AN5895.2 | 72.m19235 | 20082.m00039
Sc PDC1/ SPAC3H8.01 |  | pyruvate decarboxylase | AN4888.2 | 59.m08784 | 20175.m00382
Sc OXR1/ SPAC8C9.16C |  | unknown function | AN3004.2 | 59.m09010 | 20174.m00378
Sc KGD1// SPBC3H7.03C |  | mitochondrial alpha-ketoglutarate dehydrogenase complex | AN5571.2 | 58.m07497 | 20165.m00219
Sc DAP1/ SPAC26H5.15 |  | Sc damage response, related to mammalian membrane progesterone receptors | AN4939.2 | 59.m08843 | 20175.m00316
* homology limited to functional domain
**present but missing in official annotation
Sc=Saccharomycese cerevisiae; Sp=Schizosaccharomyces pombe; [NAME] crassa; Um=Ustilago maydis; Pa=[NAME] anserina