Spreadsheet: 04eae6f4-1758-4bb0-b6f7-8c8b085cba2a
Sheet: Sheet1

Representative Public ID | [NAME] | [NAME] | Coincidence Cluster . | p value | Change | Fold change | Probe Set ID | OMIM | Ensembl | UniGene ID | [NAME] | [NAME] | GO Biological Process Description | GO Molecular Function Description | GO Cellular Component Description | [NAME] | [NAME]
X68149 | Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) | [NAME] | 3-1 | 0.027945687 | decreased | 3.231322465313313 | 1003_s_at | 601613 | ENSG00000160683 | 113916 | 643 | NM_001716 /// NM_032966 | cell motility /// signal transduction /// G-protein coupled receptor protein signaling pathway /// B-cell activation | rhodopsin-like receptor activity /// receptor activity /// angiotensin type II receptor activity /// C-X-C chemokine receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
U41068 | collagen, type XI, alpha 2 | COL11A2 | 2-9 | 0.042146038 | increased | 1.438505977361499 | 1027_at | 120290 /// 184840 /// 215150 /// 277610 /// 601868 | ENSG00000112112 | 390171 | 1302 | NM_080679 /// NM_080680 /// NM_080681 | skeletal development /// phosphate transport /// cell adhesion /// perception of sound /// collagen fibril organization | extracellular matrix structural constituent conferring tensile strength | [NAME] /// collagen type XI /// cytoplasm | --- | ---
U43431 | topoisomerase (DNA) III alpha | TOP3A | 1-8 | 0.040945893 | increased | 1.073354392334331 | 1028_at | 601243 | ENSG00000177302 | 435124 | 7156 | NM_004618 | DNA topological change /// DNA unwinding /// DNA modification /// chromosome organization and biogenesis (sensu [NAME]) /// meiosis | DNA topoisomerase type I activity /// zinc ion binding | nucleus | --- | ---
M77810 | GATA binding protein 2 | GATA2 | 5-3 | 0.034735387 | decreased | 1.884047015700183 | 1071_at | 137295 | ENSG00000179348 | 367725 | 2624 | [NAME] | transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// phagocytosis /// positive regulation of phagocytosis | transcription factor activity | nucleus | --- | ---
M31667 | cytochrome P450, family 1, subfamily A, polypeptide 2 | CYP1A2 | 8-3 | 0.02479557 | decreased | 1.605511939372746 | 1080_s_at | 124060 | ENSG00000140505 | 1361 | 1544 | NM_000761 | electron transport /// transport | electron transporter activity /// oxygen binding /// unspecific monooxygenase activity | endoplasmic reticulum /// microsome /// membrane | Fatty acid metabolism /// gamma-Hexachlorocyclohexane degradation /// Tryptophan metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00071+1.14.14.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00361+1.14.14.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+1.14.14.1
M64936 | --- | --- | 5-4 | 0.019244254 | decreased | 2.479299636973956 | 1089_i_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
M65254 | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform | PPP2R1B | 9-1 | 0.014262452 | decreased | 1.653598368112932 | 1093_at | 211980 /// 603113 | ENSG00000137713 | 269128 | 5519 | NM_002716 /// NM_181699 | regulation of cell cycle /// inactivation of MAPK /// regulation of DNA replication /// regulation of translation /// protein complex assembly /// protein amino acid dephosphorylation /// ceramide metabolism /// induction of apoptosis /// RNA splicing /// response to organic substance /// second-messenger-mediated signaling /// regulation of Wnt receptor signaling pathway /// regulation of cell adhesion /// negative regulation of cell growth /// regulation of growth /// negative regulation of tyrosine phosphorylation of Stat3 protein /// regulation of transcription /// regulation of cell differentiation | protein phosphatase type 2A activity /// antigen binding /// phosphoprotein phosphatase activity /// binding /// protein binding /// protein phosphatase type 2A regulator activity /// hydrolase activity /// protein heterodimerization activity | protein phosphatase type 2A complex /// soluble fraction /// nucleus /// mitochondrion /// cytosol /// microtubule cytoskeleton /// membrane | Glycogen_Metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Glycogen_Metabolism/Hs_Glycogen_Metabolism.htm
M65254 | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform | PPP2R1B | 10-3 | 0.003865402 | decreased | 1.100204233704176 | 1094_g_at | 211980 /// 603113 | ENSG00000137713 | 269128 | 5519 | NM_002716 /// NM_181699 | regulation of cell cycle /// inactivation of MAPK /// regulation of DNA replication /// regulation of translation /// protein complex assembly /// protein amino acid dephosphorylation /// ceramide metabolism /// induction of apoptosis /// RNA splicing /// response to organic substance /// second-messenger-mediated signaling /// regulation of Wnt receptor signaling pathway /// regulation of cell adhesion /// negative regulation of cell growth /// regulation of growth /// negative regulation of tyrosine phosphorylation of Stat3 protein /// regulation of transcription /// regulation of cell differentiation | protein phosphatase type 2A activity /// antigen binding /// phosphoprotein phosphatase activity /// binding /// protein binding /// protein phosphatase type 2A regulator activity /// hydrolase activity /// protein heterodimerization activity | protein phosphatase type 2A complex /// soluble fraction /// nucleus /// mitochondrion /// cytosol /// microtubule cytoskeleton /// membrane | Glycogen_Metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Glycogen_Metabolism/Hs_Glycogen_Metabolism.htm
[NAME] | chemokine (C-C motif) receptor 7 | CCR7 | 1-7 | 0.028750557 | increased | 2.669913521841401 | 1097_s_at | 600242 | ENSG00000126353 | 370036 | 1236 | NM_001838 | chemotaxis /// inflammatory response /// signal transduction /// G-protein coupled receptor protein signaling pathway /// positive regulation of cytosolic calcium ion concentration /// antimicrobial humoral response (sensu Vertebrata) | rhodopsin-like receptor activity /// receptor activity /// C-C chemokine receptor activity | plasma membrane /// integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
L38503 | glutathione S-transferase theta 2 | GSTT2 | 6-2 | 0.021862032 | decreased | 1.654803661771301 | 1099_s_at | 600437 | ENSG00000133433 | 1581 | 2953 | NM_000854 | --- | glutathione transferase activity /// transferase activity | --- | Glutathione metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00480+2.5.1.18
M11567 | angiogenin, ribonuclease, RNase A family, 5 /// ribonuclease, RNase A family, 4 | ANG /// RNASE4 | 5-2 | 0.018714622 | decreased | 1.892548523894074 | 1103_at | 105850 /// 601030 | ENSG00000181784 | 283749 | 283 /// 6038 | NM_001145 /// NM_002937 /// NM_194430 /// NM_194431 | angiogenesis /// RNA catabolism /// negative regulation of protein biosynthesis /// cell differentiation /// mRNA cleavage | nucleic acid binding /// endonuclease activity /// pancreatic ribonuclease activity /// hydrolase activity /// pancreatic ribonuclease activity | --- | --- | ---
HG3432-HT3621 | --- | --- | 7-3 | 0.03467345 | decreased | 3.07338006793115 | 1145_g_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
HG2846-HT2983 | --- | --- | 7-3 | 0.018149575 | decreased | 1.391444674329168 | 1178_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
D13168 | endothelin receptor type B | EDNRB | 7-4 | 0.025396239 | decreased | 2.125246484794181 | 1198_at | 131244 /// 600155 /// 600501 | ENSG00000136160 | 82002 | 1910 | NM_000115 /// NM_003991 | negative regulation of adenylate cyclase activity /// G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) /// neurogenesis /// perception of sound | rhodopsin-like receptor activity /// receptor activity /// endothelin receptor activity | plasma membrane /// integral to plasma membrane | Prostaglandin_synthesis_regulation /// GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs | [NAME] /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
D26528 | --- | --- | 2-9 | 0.023467637 | increased | 3.484240900320099 | 1205_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
X66360 | PCTAIRE protein kinase 2 | PCTK2 | 4-9 | 0.01925318 | increased | 2.182501445680494 | 1222_at | 603440 | ENSG00000059758 | 506415 | 5128 | NM_002595 | regulation of cell cycle /// protein amino acid phosphorylation | protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity | --- | Phosphatidylinositol signaling system | www.genome.ad.jp/dbget-bin/show_pathway?MAP04070+2.7.1.37
M89914 | neurofibromin 1 (neurofibromatosis, [NAME] disease, [NAME] disease) | NF1 | 5-3 | 0.000743646 | decreased | 1.697205624705224 | 1236_s_at | 162200 /// 162210 /// 193520 /// 601321 /// 607785 | ENSG00000196712 | 435956 | 4763 | NM_000267 | cell cycle /// [NAME] protein signal transduction /// negative regulation of cell proliferation /// negative regulation of cell cycle | enzyme inhibitor activity /// Ras GTPase activator activity | cytoplasm | --- | ---
[NAME] | --- | --- | 10-3 | 0.010482703 | decreased | 1.664283504440183 | 1281_f_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
U53174 | RAD9 homolog A (S. pombe) | RAD9A | 8-3 | 0.033977729 | decreased | 1.383336967305176 | 1324_at | 603761 | ENSG00000172613 | 240457 | 5883 | NM_004584 | regulation of cell cycle /// DNA replication checkpoint /// DNA damage checkpoint /// DNA repair | --- | nucleus | --- | ---
U11870 | interleukin 8 receptor, alpha | IL8RA | 6-2 | 0.03927048 | decreased | 2.2619018412039 | 1352_at | 146929 | ENSG00000163464 | 194778 | 3577 | NM_000634 | chemotaxis /// inflammatory response /// G-protein coupled receptor protein signaling pathway /// sensory perception | rhodopsin-like receptor activity /// receptor activity /// interleukin-8 receptor activity | membrane /// integral to membrane | GPCRDB_Class_A_Rhodopsin-like /// GPCRDB_Other /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Other/Hs_GPCRDB_Other.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
D26561 | --- | --- | 7-3 | 0.008369524 | decreased | 1.507827549711503 | 1416_g_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
[NAME] | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | PTPN4 | 4-9 | 0.013574524 | increased | 1.869179493973027 | 1459_at | 176878 | ENSG00000088179 | 469809 | 5775 | NM_002830 | protein amino acid dephosphorylation | non-membrane spanning protein tyrosine phosphatase activity /// structural molecule activity /// cytoskeletal protein binding /// hydrolase activity | cytoplasm /// cytoskeleton /// membrane | --- | ---
Z70276 | fibroblast growth factor 12 | FGF12 | 10-3 | 0.023243439 | decreased | 1.911152569514396 | 1504_s_at | 601513 | ENSG00000114279 | 185577 | 2257 | NM_004113 /// NM_021032 | --- | growth factor activity | nucleus | --- | ---
D11086 | interleukin 2 receptor, gamma (severe combined immunodeficiency) | IL2RG | 10-4 | 0.039193555 | decreased | 2.197818300597974 | 1506_at | 300400 /// 308380 /// 312863 | ENSG00000147168 | 84 | 3561 | NM_000206 | protein complex assembly /// immune response /// signal transduction /// cell proliferation | receptor activity /// hematopoietin/interferon-class (D200-domain) cytokine receptor activity /// interleukin-2 receptor activity /// interleukin-4 receptor activity /// interleukin-7 receptor activity | integral to plasma membrane /// membrane | Inflammatory_Response_Pathway | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Inflammatory_Response_Pathway/Hs_Inflammatory_Response_Pathway.htm
D25303 | integrin, alpha 9 | ITGA9 | 10-3 | 0.030531713 | decreased | 1.200552452567344 | 1508_at | 603963 | ENSG00000144668 | 113157 | 3680 | NM_002207 | cell-matrix adhesion /// integrin-mediated signaling pathway | receptor activity /// protein binding | [NAME] /// integral to membrane | Integrin-mediated_cell_adhesion_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Integrin-mediated_cell_adhesion_KEGG/Hs_Integrin-mediated_cell_adhesion_KEGG.htm
U77949 | CDC6 cell division cycle 6 homolog (S. cerevisiae) | CDC6 | 7-3 | 0.016494623 | decreased | 1.566607291052481 | 1536_at | 602627 | ENSG00000094804 | 405958 | 990 | NM_001254 | DNA replication checkpoint /// regulation of cyclin dependent protein kinase activity /// cytokinesis /// DNA replication /// cell cycle /// mitosis /// traversing start control point of mitotic cell cycle /// negative regulation of DNA replication /// negative regulation of cell proliferation | nucleotide binding /// ATP binding /// nucleoside-triphosphatase activity | nucleus /// cytoplasm | Cell_cycle_KEGG /// DNA_replication_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_DNA_replication_Reactome/Hs_DNA_replication_Reactome.htm
M27318 | interferon, alpha 4 | IFNA4 | 6-2 | 0.018767013 | decreased | 1.752920765536794 | 1580_f_at | 147564 | ENSG00000147877 | 1510 | 3441 | NM_021068 | defense response /// cell-cell signaling /// response to virus | [NAME]/interferon-class (D200-domain) cytokine receptor binding /// interferon-alpha/beta receptor binding | extracellular region /// extracellular region | --- | ---
U09578 | mitogen-activated protein kinase-activated protein kinase 3 | MAPKAPK3 | 6-3 | 0.030832355 | decreased | 1.850216405058256 | 1637_at | 602130 | ENSG00000114738 | 234521 | 7867 | NM_004635 | protein amino acid phosphorylation /// response to stress /// signal transduction | protein serine/threonine kinase activity /// MAP kinase kinase activity /// ATP binding /// transferase activity | nucleus | --- | ---
U36764 | eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa | EIF3S2 | 10-3 | 0.014697869 | decreased | 1.74681994172214 | 1644_at | 603911 | ENSG00000084623 | 530096 | 8668 | NM_003757 | protein biosynthesis /// regulation of translational initiation | translation initiation factor activity | eukaryotic translation initiation factor 3 complex | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
D29013 | polymerase (DNA directed), beta | POLB | 7-4 | 0.036745677 | decreased | 1.384843865444574 | 1696_at | 174760 | ENSG00000070501 | 521563 | 5423 | NM_002690 | DNA-dependent DNA replication /// DNA repair | magnesium ion binding /// DNA binding /// beta DNA polymerase activity /// DNA nucleotidylexotransferase activity /// transferase activity /// lyase activity | nucleus | Nucleotide_Metabolism /// Purine metabolism /// Pyrimidine metabolism /// DNA polymerase | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Nucleotide_Metabolism/Hs_Nucleotide_Metabolism.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+2.7.7.7 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00240+2.7.7.7 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03030+2.7.7.7
D37781 | protein tyrosine phosphatase, receptor type, J | PTPRJ | 9-3 | 0.016923417 | decreased | 2.537927078718126 | 1697_s_at | 114500 /// 600925 | ENSG00000149177 | 318547 | 5795 | NM_002843 | protein amino acid dephosphorylation /// transmembrane receptor [NAME] signaling pathway /// cell-cell signaling | [NAME] receptor protein tyrosine phosphatase activity /// hydrolase activity | integral to plasma membrane | --- | ---
HG1112-HT1112 | --- | --- | 3-3 | 0.018951184 | decreased | 1.941316997124208 | 1840_g_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
HG2724-HT2820 | --- | --- | 6-3 | 0.043966204 | decreased | 2.930800288171195 | 1842_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
X94216 | vascular endothelial growth factor C | VEGFC | 2-9 | 0.009297865 | increased | 2.062240591519883 | 1934_s_at | 601528 | ENSG00000150630 | 435215 | 7424 | NM_005429 | regulation of cell cycle /// angiogenesis /// substrate-bound cell migration /// signal transduction /// lymph gland development /// cell proliferation /// positive regulation of cell proliferation /// cell differentiation | growth factor activity | membrane | --- | ---
U37022 | cyclin-dependent kinase 4 | CDK4 | 10-3 | 0.026806905 | decreased | 0.9792267686202367 | 1942_s_at | 123829 | ENSG00000135446 | 95577 | 1019 | NM_000075 | regulation of cell cycle /// G1/S transition of mitotic cell cycle /// cytokinesis /// protein amino acid phosphorylation /// cell proliferation | protein kinase activity /// cyclin-dependent protein kinase activity /// ATP binding /// transferase activity | --- | Cell_cycle_KEGG /// G1_to_S_cell_cycle_Reactome /// Ovarian_Infertility_Genes | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G1_to_S_cell_cycle_Reactome/Hs_G1_to_S_cell_cycle_Reactome.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Ovarian_Infertility_Genes/Hs_Ovarian_Infertility_Genes.htm
X51688 | cyclin A2 | [NAME] | 4-9 | 0.04126863 | increased | 1.951852342800687 | 1943_at | 123835 | ENSG00000145386 | 85137 | 890 | NM_001237 | regulation of cyclin dependent protein kinase activity /// cytokinesis /// mitosis /// mitotic G2 checkpoint | --- | nucleus | [NAME] | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm
U17105 | cyclin F | CCNF | 2-9 | 0.012325273 | increased | 1.51020139277891 | 1996_s_at | 600227 | ENSG00000162063 | 1973 | 899 | NM_001761 | regulation of cell cycle /// cytokinesis /// mitosis | --- | nucleus | --- | ---
M80261 | [NAME] nuclease (multifunctional DNA repair enzyme) 1 | APEX1 | 2-9 | 0.017147886 | increased | 1.924614358745491 | 2025_s_at | 107748 | ENSG00000100823 | 73722 | 328 | NM_001641 /// NM_080648 /// NM_080649 | base-excision repair /// transcription from RNA polymerase II promoter /// regulation of DNA binding | DNA binding /// transcription coactivator activity /// transcription corepressor activity /// DNA-(apurinic or apyrimidinic site) lyase activity /// endodeoxyribonuclease activity /// ribonuclease H activity /// phosphodiesterase I activity /// uracil DNA N-glycosylase activity /// protein binding /// 3'-5' exonuclease activity /// oxidoreductase activity /// lyase activity /// metal ion binding | nucleus /// endoplasmic reticulum /// ribosome /// perinuclear region | --- | ---
M15024 | [NAME] myeloblastosis viral oncogene homolog (avian) | MYB | 7-4 | 0.04321096 | decreased | 1.197153625615421 | 2042_s_at | 189990 | ENSG00000118513 | 531941 | 4602 | NM_005375 | regulation of transcription, DNA-dependent | DNA binding /// transcriptional activator activity | nuclear matrix | --- | ---
L22475 | BCL2-associated X protein | BAX | 5-4 | 0.002430316 | decreased | 1.866429167290816 | 2067_f_at | 600040 | ENSG00000087088 | 159428 | 581 | NM_004324 /// NM_138761 /// NM_138762 /// NM_138763 /// NM_138764 /// NM_138765 | apoptosis /// induction of apoptosis /// cell cycle /// germ cell development /// induction of apoptosis by extracellular signals /// negative regulation of survival gene product activity /// apoptotic mitochondrial changes /// regulation of apoptosis /// negative regulation of cell cycle | --- | integral to membrane | Apoptosis /// Apoptosis_GenMAPP /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_GenMAPP/Hs_Apoptosis_GenMAPP.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
M60165 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | GNAO1 | 10-3 | 0.039893941 | decreased | 0.9049126182836089 | 236_at | 139311 | ENSG00000087258 | 241431 | 2775 | NM_020988 /// NM_138736 | muscle contraction /// signal transduction /// G-protein coupled receptor protein signaling pathway /// neurogenesis /// axon guidance | GTPase activity /// receptor signaling protein activity /// GTP binding | --- | G_Protein_Signaling /// Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
[NAME] | [NAME] (TNF superfamily, member 1) | LTA | 2-9 | 0.022736961 | increased | 1.161356459287283 | 258_at | 153440 | ENSG00000173503 | 36 | 4049 | NM_000595 | induction of apoptosis /// immune response /// signal transduction /// cell-cell signaling | tumor necrosis factor receptor binding | membrane | Apoptosis /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
L19778 | histone 1, H2ag | HIST1H2AG | 2-9 | 0.023718929 | increased | 0.9793716727747476 | 285_g_at | --- | ENSG00000196787 /// [NAME] /// ENSG00000184348 /// ENSG00000198374 /// ENSG00000196866 | 51011 | 8969 | /// NM_021064 | --- | --- | --- | --- | ---
L32831 | G protein-coupled receptor 3 | GPR3 | 6-2 | 0.015139625 | decreased | 1.937723829334945 | 290_s_at | 600241 | ENSG00000181773 | 66542 | 2827 | NM_005281 | signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein signaling, adenylate [NAME] | rhodopsin-like receptor activity /// receptor activity /// G-protein coupled receptor activity, unknown ligand | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm
HG881-HT881 | --- | --- | 7-3 | 0.043595667 | decreased | 1.548381287787884 | 301_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
J03756 | growth hormone 2 | GH2 | 6-2 | 0.019900929 | decreased | 2.348209737433818 | 308_f_at | 139240 | ENSG00000136488 | 406754 | 2689 | /// NM_002059 /// NM_022556 /// NM_022557 /// NM_022558 | --- | cytokine activity /// hormone activity /// hormone activity | extracellular region | --- | ---
U50277 | --- | --- | 2-9 | 0.013421573 | increased | 2.281692733509482 | 31309_r_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
X61070 | Vd7 gene for T-cell receptor V-delta-7 | --- | 1-8 | 0.007067692 | increased | 2.22754963478705 | 31311_at | --- | --- | 121492 | --- | --- | --- | --- | --- | --- | ---
U82306 | Unknown protein | --- | 7-3 | 0.021595366 | decreased | 1.465287938028617 | 31325_at | --- | --- | 550143 | --- | --- | --- | --- | --- | --- | ---
AF016492 | UDP glycosyltransferase 2 family, polypeptide B11 | UGT2B11 | 10-3 | 0.0212411 | decreased | 2.486209680286057 | 31382_f_at | 603064 | ENSG00000198277 | 339811 | 10720 | NM_001073 | xenobiotic metabolism /// metabolism /// estrogen metabolism | glucuronosyltransferase activity | endoplasmic reticulum /// microsome /// integral to membrane | --- | ---
AF040723 | huntingtin-associated protein 1 (neuroan 1) | HAP1 | 1-6 | 0.023330416 | increased | 1.584695208622509 | 31391_at | 600947 | ENSG00000173805 | 158300 | 9001 | NM_003949 /// NM_177977 | synaptic transmission /// development | --- | [NAME] | --- | ---
AB018332 | KIAA0789 gene product | KIAA0789 | 6-3 | 0.021274705 | decreased | 1.708969558655009 | 31401_r_at | --- | ENSG00000075035 | 143591 | 9671 | NM_014653 | --- | transferase activity | --- | --- | ---
AE000659 | T-cell antigen receptor alpha chain /// T cell receptor alpha locus | TRA@ | 9-1 | 0.010409059 | decreased | 2.408191896513608 | 31430_at | 186880 | --- | 512110 /// 525223 | 6955 | --- | cellular defense response | receptor activity /// MHC protein binding /// peptide antigen binding | integral to plasma membrane | --- | ---
AF090327 | a disintegrin and metalloproteinase domain 7 | ADAM7 | 3-3 | 0.043126303 | decreased | 3.11653035630826 | 31435_at | 607310 | ENSG00000069206 | 166003 | 8756 | NM_003817 | proteolysis and peptidolysis | metalloendopeptidase activity | integral to membrane | --- | ---
S76346 | runt-related transcription factor 1 (acute myeloid leukemia 1; [NAME]) | [NAME] | 2-9 | 0.012612897 | increased | 1.168678013522916 | 31443_at | 151385 /// 180300 /// 601399 /// 601626 | ENSG00000159216 | 149261 | 861 | NM_001001890 /// NM_001754 | transcription /// regulation of transcription, DNA-dependent /// development | transcription factor activity /// protein binding /// ATP binding | nucleus | --- | ---
X72882 | --- | --- | 9-3 | 0.012841884 | decreased | 1.787396504813998 | 31484_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
M86868 | gamma-aminobutyric acid (GABA) receptor, rho 2 | GABRR2 | 7-4 | 0.025139662 | decreased | 3.03058069079443 | 31551_at | 137162 | ENSG00000111886 | 99927 | 2570 | NM_002043 | ion transport /// signal transduction /// synaptic transmission | GABA-A receptor activity /// ion channel activity /// extracellular ligand-gated ion channel activity /// neurotransmitter receptor activity | integral to plasma membrane /// postsynaptic membrane | --- | ---
U93163 | melanoma antigen family B, 4 | MAGEB4 | 3-3 | 0.018887103 | decreased | 1.509862786226663 | 31582_at | 300153 | ENSG00000120289 | 113291 | 4115 | NM_002367 | --- | --- | --- | --- | ---
[NAME] | UDP-galactose-4-epimerase | GALE | 10-3 | 0.023186904 | decreased | 1.610403320549604 | 31598_s_at | 230350 /// 606953 | ENSG00000117308 | 76057 | 2582 | NM_000403 /// NM_001008216 | carbohydrate metabolism /// galactose metabolism /// nucleotide-sugar metabolism | UDP-glucose 4-epimerase activity /// UDP-glucose 4-epimerase activity /// isomerase activity | --- | Galactose metabolism /// Nucleotide sugars metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00052+5.1.3.2 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00520+5.1.3.2
AF083384 | RNA binding motif protein 17 | RBM17 | 9-3 | 0.0120769 | decreased | 2.022426163267374 | 31630_at | 606935 | ENSG00000134453 | 498548 | 84991 | NM_032905 | nuclear mRNA splicing, via spliceosome | nucleotide binding /// RNA binding | spliceosome complex | mRNA_processing_Reactome | [NAME]
AJ133776 | neurogenin 3 | NEUROG3 | 6-2 | 0.022218032 | decreased | 2.086235723201345 | 31658_at | 604882 | ENSG00000122859 | 532682 | 50674 | NM_020999 | transcription /// regulation of transcription, DNA-dependent /// central nervous system development /// peripheral nervous system development /// cell differentiation | DNA binding | nucleus | --- | ---
U82382 | protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1-like | PIN1L | 10-3 | 0.024401845 | decreased | 2.069988686505909 | 31717_at | 602051 | --- | 546274 | 5301 | --- | --- | --- | --- | --- | ---
AJ000327 | ATP-binding cassette, sub-family D (ALD), member 2 | ABCD2 | 2-9 | 0.017203907 | increased | 2.060340462557278 | 31718_at | 601081 | ENSG00000173208 | 117852 | 225 | NM_005164 | fatty acid metabolism /// transport | ATP binding /// ATPase activity /// ATPase activity, coupled to transmembrane movement of substances | peroxisome /// integral to plasma membrane /// membrane /// ATP-binding cassette (ABC) transporter complex | --- | ---
AF007194 | mucin 3A, intestinal | MUC3A | 1-7 | 0.022932143 | increased | 1.938776588700891 | 31745_at | 158371 /// 191390 | ENSG00000169894 | 533959 | 4584 | XM_374502 | maintenance of gastrointestinal epithelium | extracellular matrix constituent, lubricant activity | extracellular region | --- | ---
Y11094 | wingless-type MMTV integration site family, member 8B | WNT8B | 7-4 | 0.011037903 | decreased | 1.208887261010039 | 31769_at | 601396 | ENSG00000075290 | 421281 | 7479 | NM_003393 | signal transduction /// frizzled-2 signaling pathway /// cell-cell signaling /// development /// neurogenesis | signal transducer activity | extracellular region | --- | ---
U65652 | CMT1A duplicated region transcript 1 | CDRT1 | 9-3 | 0.029438725 | decreased | 1.128805320664983 | 31781_at | --- | ENSG00000108445 | 454698 | 374286 | NM_006382 | --- | --- | --- | --- | ---
Y16961 | tumor protein p73-like | TP73L | 2-5 | 0.036636932 | increased | 1.65330958752753 | 31791_at | 103285 /// 106260 /// 603273 /// 603543 /// 604292 /// 605289 | ENSG00000073282 | 137569 | 8626 | NM_003722 | transcription /// apoptosis /// induction of apoptosis /// development /// positive regulation of Notch signaling pathway /// negative regulation of transcription, DNA-dependent /// positive regulation of transcription, DNA-dependent /// protein homotetramerization | transcription factor activity /// transcriptional activator activity /// transcriptional repressor activity /// protein self binding | nucleus | --- | ---
[NAME] | 5'-nucleotidase, cytosolic II | [NAME] | 4-10 | 0.002426493 | increased | 1.27757101184021 | 31794_at | 600417 | ENSG00000076685 | 158209 | 22978 | NM_012229 | --- | 5'-nucleotidase activity /// hydrolase activity | [NAME] | --- | ---
AJ224819 | ret finger protein 2 | [NAME] | 4-7 | 0.028685013 | increased | 1.543175526660363 | 31851_at | 605661 | ENSG00000198553 | 436922 | 10206 | NM_001007278 /// NM_005798 /// NM_052811 /// NM_213590 | potassium ion transport /// cell cycle /// morphogenesis /// protein ubiquitination /// positive regulation of I-kappaB kinase/NF-kappaB cascade /// negative regulation of cell cycle | ubiquitin-protein ligase activity /// signal transducer activity /// voltage-gated potassium channel activity /// protein binding /// zinc ion binding | ubiquitin ligase complex /// voltage-gated potassium channel complex /// membrane | --- | ---
AF035582 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | CASK | 1-9 | 0.035988592 | increased | 2.358757485381749 | 31854_at | 300172 | ENSG00000147044 | 495984 | 8573 | NM_003688 | protein amino acid phosphorylation /// cell adhesion | guanylate kinase activity /// protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// protein binding /// calmodulin binding /// ATP binding /// transferase activity | [NAME] | --- | ---
AF060798 | serine/threonine kinase 16 | STK16 | 10-3 | 0.013656181 | decreased | 1.723850661679345 | 31868_at | 604719 | ENSG00000115661 | 153003 | 8576 | NM_001008910 /// NM_003691 | protein complex assembly /// protein amino acid phosphorylation /// protein amino acid phosphorylation | protein serine/threonine kinase activity /// protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity | --- | --- | ---
AF049703 | E74-like factor 5 (ets domain transcription factor) | ELF5 | 5-4 | 0.010496979 | decreased | 1.76150165295137 | 31913_at | 605169 | ENSG00000135374 | 11713 | 2001 | NM_001422 /// NM_198381 | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// cell proliferation | DNA binding /// transcription factor activity | nucleus | --- | ---
AF004841 | cell adhesion molecule-related/down-regulated by oncogenes | CDON | 5-4 | 0.00228907 | decreased | 1.606241991081747 | 31920_at | 608707 | ENSG00000064309 | 530804 | 50937 | NM_016952 | cell adhesion | protein binding | membrane | --- | ---
L26584 | [NAME] protein-specific guanine nucleotide-releasing factor 1 | RASGRF1 | 8-3 | 0.023760639 | decreased | 1.065294236546599 | 31925_s_at | 606600 | ENSG00000058335 | 459035 | 5923 | NM_002891 /// NM_153815 | small GTPase mediated signal transduction /// long-term memory | [NAME] guanyl-nucleotide exchange factor activity | plasma membrane /// synaptosome | --- | ---
AF035835 | nephrosis 1, congenital, Finnish type (nephrin) | NPHS1 | 3-2 | 0.005160693 | decreased | 2.542226697205229 | 31967_at | 256300 /// 602716 | --- | 122186 | 4868 | NM_004646 | cell adhesion /// excretion | protein binding | integral to plasma membrane | --- | ---
AJ132445 | claudin 14 | CLDN14 | 7-3 | 0.037650841 | decreased | 1.661580879702994 | 31974_at | 605608 | ENSG00000159261 | 505146 | 23562 | NM_012130 /// NM_144492 | protein complex assembly /// perception of sound /// calcium-independent cell-cell adhesion | structural molecule activity /// protein self binding | tight junction /// membrane /// integral to membrane | --- | ---
AF009624 | [NAME] member 17 | KIF17 | 1-6 | 0.030760122 | increased | 3.152629930778641 | 31990_at | 605037 | ENSG00000117245 | 130411 | 57576 | NM_020816 | microtubule-based movement /// protein transport | microtubule motor activity /// ATP binding | microtubule associated complex | --- | ---
AL021807 | histone 1, H2ah | HIST1H2AH | 5-2 | 0.036631941 | decreased | 2.155785386455654 | 31992_f_at | --- | ENSG00000196787 /// ENSG00000184825 /// [NAME] /// ENSG00000184348 /// ENSG00000198374 /// ENSG00000196866 | 352225 | 85235 | /// NM_080596 | nucleosome assembly /// chromosome organization and biogenesis (sensu [NAME]) | DNA binding | nucleosome /// nucleus | --- | ---
D10495 | protein kinase C, delta | PRKCD | 10-3 | 0.001535573 | decreased | 1.614790036420246 | 32046_at | 176977 | ENSG00000163932 | 155342 | 5580 | NM_006254 /// NM_212539 | protein amino acid phosphorylation /// protein amino acid phosphorylation /// intracellular signaling cascade | protein serine/threonine kinase activity /// diacylglycerol-activated phospholipid-dependent protein kinase C activity /// protein binding /// ATP binding /// transferase activity /// diacylglycerol binding | cytoplasm /// membrane | G_Protein_Signaling /// Wnt_signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
AL050173 | chromosome 21 open reading frame 25 | C21orf25 | 10-3 | 0.014308952 | decreased | 1.40443333728522 | 32107_at | --- | ENSG00000157617 | 473894 | 25966 | NM_199050 | --- | --- | --- | --- | ---
AL030996 | THO complex 2 | [NAME] | 4-9 | 0.007839377 | increased | 1.672081221693454 | 32124_at | 300395 | ENSG00000125676 | 149991 | 57187 | NM_020449 | nuclear mRNA splicing, via spliceosome /// mRNA-nucleus export /// transport | RNA binding | nucleus | --- | ---
AL046649 | zinc finger DAZ interacting protein 3 | DZIP3 | 2-9 | 0.015501489 | increased | 1.703440043203021 | 32132_at | 608672 | ENSG00000198919 | 409210 | 9666 | NM_014648 | protein ubiquitination | RNA binding /// ubiquitin-protein ligase activity /// zinc ion binding /// ligase activity | ubiquitin ligase complex | --- | ---
Y08110 | sortilin-related receptor, L(DLR class) A repeats-containing | SORL1 | 3-1 | 0.026375441 | decreased | 2.046201177375369 | 32140_at | 602005 | ENSG00000137642 | 368592 | 6653 | NM_003105 | lipid metabolism /// lipid transport /// receptor mediated endocytosis /// steroid metabolism /// cholesterol metabolism | [NAME] receptor activity /// lipid transporter activity | integral to plasma membrane /// membrane | --- | ---
AB008430 | FERM, [NAME] (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | FARP1 | 8-3 | 0.043156422 | decreased | 1.084329420088685 | 32147_at | 602654 | ENSG00000152767 | 403917 | 10160 | NM_001001715 /// NM_005766 | --- | Rho guanyl-nucleotide exchange factor activity /// binding /// cytoskeletal protein binding | cytoplasm /// cytoskeleton /// cytoskeleton /// membrane | --- | ---
AB020685 | Rho-related BTB domain containing 3 | RHOBTB3 | 9-1 | 0.007128173 | decreased | 2.633294309793501 | 32215_i_at | 607353 | ENSG00000164292 | 445030 | 22836 | NM_014899 | --- | GTPase activity /// protein binding | --- | --- | ---
AL050106 | Hypothetical protein FLJ12610 | FLJ12610 | 2-9 | 0.023420574 | increased | 0.775838690510633 | 32231_at | --- | ENSG00000187736 | 225988 | 79840 | NM_024782 | electron transport | electron transporter activity | --- | --- | ---
AL045811 | Hypothetical protein PRO2730 | PRO2730 | 8-3 | 0.031637309 | decreased | 1.535108052002088 | 32248_at | --- | ENSG00000164091 | 194110 | 80335 | NM_025222 | --- | --- | --- | --- | ---
L23134 | granzyme M (lymphocyte met-ase 1) | GZMM | 6-2 | 0.026459066 | decreased | 1.630880558807472 | 32264_at | 600311 | ENSG00000197540 | 465511 | 3004 | NM_005317 | proteolysis and peptidolysis /// cytolysis | chymotrypsin activity /// trypsin activity | --- | --- | ---
HG1019-HT1019 | --- | --- | 3-1 | 0.010580709 | decreased | 2.918010198989685 | 323_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
AF035594 | protein kinase C, alpha | PRKCA | 8-3 | 0.035662777 | decreased | 0.987674619721237 | 32304_at | 176960 | ENSG00000154229 | 531704 | 5578 | NM_002737 | regulation of cell cycle /// protein amino acid phosphorylation /// cell surface receptor linked signal transduction /// intracellular signaling cascade /// induction of apoptosis by extracellular signals | protein kinase C activity /// protein-tyrosine kinase activity /// calcium ion binding /// ATP binding /// transferase activity /// diacylglycerol binding | membrane fraction | G_Protein_Signaling /// Wnt_signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction /// Phosphatidylinositol signaling system | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP04070+2.7.1.37
M57951 | UDP glycosyltransferase 1 family, polypeptide A10 /// UDP glycosyltransferase 1 family, polypeptide A8 /// UDP glycosyltransferase 1 family, polypeptide A7 /// UDP glycosyltransferase 1 family, polypeptide A6 /// UDP glycosyltransferase 1 family, polypeptide A5 /// UDP glycosyltransferase 1 family, polypeptide A9 /// UDP glycosyltransferase 1 family, polypeptide A4 /// UDP glycosyltransferase 1 family, polypeptide [NAME] /// UDP glycosyltransferase 1 family, polypeptide [NAME] | UGT1A10 /// UGT1A8 /// UGT1A7 /// UGT1A6 /// UGT1A5 /// UGT1A9 /// UGT1A4 /// UGT1A1 /// UGT1A3 | 3-3 | 0.009292421 | decreased | 2.02383247487722 | 32392_s_at | 606435 /// 606433 /// 606432 /// 606431 /// 606430 /// 606434 /// 606429 /// 143500 /// 191740 /// 218800 /// 237900 /// 606785 /// 606428 | ENSG00000167165 | 124112 | 54575 /// 54576 /// 54577 /// 54578 /// 54579 /// 54600 /// 54657 /// 54658 /// 54659 | /// NM_000463 /// NM_001072 /// NM_007120 /// NM_019075 /// NM_019076 /// NM_019077 /// NM_019078 /// NM_019093 /// NM_021027 /// NM_205862 | metabolism /// metabolism /// metabolism /// xenobiotic metabolism /// xenobiotic metabolism /// xenobiotic metabolism /// metabolism /// bilirubin conjugation /// digestion /// estrogen metabolism | glucuronosyltransferase activity /// UDP-glycosyltransferase activity /// transferase activity, transferring hexosyl groups | endoplasmic reticulum /// microsome /// integral to membrane /// microsome /// endoplasmic reticulum | Irinotecan_pathway_PharmGKB /// [NAME] and glucuronate interconversions /// Androgen and estrogen metabolism /// Starch and sucrose metabolism /// [NAME] and chlorophyll metabolism | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Irinotecan_pathway_PharmGKB/Hs_Irinotecan_pathway_PharmGKB.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00040+2.4.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00150+2.4.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00500+2.4.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00860+2.4.1.17
U76388 | nuclear receptor subfamily 5, group A, member 1 | NR5A1 | 7-4 | 0.005359824 | decreased | 1.963707054227625 | 32447_at | 184757 | ENSG00000136931 | 495108 | 2516 | NM_004959 | transcription /// regulation of transcription from RNA polymerase II promoter /// signal transduction /// cell-cell signaling /// primary sex determination /// male gonad development | transcription factor activity /// steroid hormone receptor activity /// transcription coactivator activity | nucleus | Ovarian_Infertility_Genes /// Nuclear_Receptors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Ovarian_Infertility_Genes/Hs_Ovarian_Infertility_Genes.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Nuclear_Receptors/Hs_Nuclear_Receptors.htm
D90278 | carcinoembryonic antigen-related cell adhesion molecule 3 | CEACAM3 | 1-6 | 0.011840766 | increased | 1.928418836719949 | 32468_f_at | 609142 | ENSG00000170956 | 11 | 1084 | NM_001815 | --- | --- | integral to membrane | --- | ---
AF080237 | Rho GDP dissociation inhibitor (GDI) gamma | ARHGDIG | 1-8 | 0.013741743 | increased | 1.845946888539458 | 32499_at | 602844 | ENSG00000185615 | 534303 | 398 | NM_001176 | negative regulation of cell adhesion /// Rho protein signal transduction | Rho GDP-dissociation inhibitor activity /// GTPase activator activity | cytoplasmic vesicle | G13_Signaling_Pathway | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G13_Signaling_Pathway/Hs_G13_Signaling_Pathway.htm
W27495 | Neurofilament 3 (150kDa medium) | NEF3 | 9-3 | 0.040090769 | decreased | 1.383614553974276 | 32513_at | 162250 | ENSG00000104722 | 458657 | 4741 | NM_005382 | --- | structural constituent of cytoskeleton | neurofilament /// axon | --- | ---
Z50853 | ClpP caseinolytic protease, ATP-dependent, proteolytic subunit homolog (E. coli) | CLPP | 10-3 | 0.012115103 | decreased | 1.429239190974062 | 32528_at | 601119 | ENSG00000125656 | 515092 | 8192 | NM_006012 | proteolysis and peptidolysis | peptidase activity /// endopeptidase Clp activity | mitochondrion | --- | ---
[NAME] | calreticulin | CALR | 3-3 | 0.043456543 | decreased | 2.146729733170784 | 32543_at | 109091 | ENSG00000179218 | 515162 | 811 | NM_004343 | regulation of transcription, DNA-dependent /// protein folding /// protein-nucleus export /// calcium ion homeostasis | DNA binding /// calcium ion binding /// sugar binding /// unfolded protein binding | endoplasmic reticulum lumen /// cytosol | Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
AI494623 | chromosome 14 open reading frame 124 | C14orf124 | 1-9 | 0.024646363 | increased | 1.461322260603262 | 32591_at | --- | ENSG00000100445 | 283111 | 56948 | NM_020195 | nucleotide-sugar metabolism | catalytic activity | --- | --- | ---
AC004382 | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | POLR2C | 9-2 | 0.004428377 | decreased | 2.280714244440002 | 32601_s_at | 180663 | ENSG00000102978 | 79402 | 5432 | NM_002694 /// NM_032940 | transcription /// transcription from RNA polymerase II promoter | DNA binding /// DNA-directed RNA polymerase activity /// transferase activity /// protein dimerization activity | nucleus /// DNA-directed RNA polymerase II, core complex | RNA_transcription_Reactome /// Purine metabolism /// Pyrimidine metabolism /// RNA polymerase | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_RNA_transcription_Reactome/Hs_RNA_transcription_Reactome.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+2.7.7.6 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00240+2.7.7.6 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03020+2.7.7.6
AI768809 | RAB1A, member RAS oncogene family | RAB1A | 8-3 | 0.022283916 | decreased | 1.598048788993917 | 32605_r_at | 179508 | ENSG00000138069 | 310645 | 5861 | NM_004161 | small GTPase mediated signal transduction /// protein transport | GTP binding | endoplasmic reticulum /// Golgi apparatus | --- | ---
M93405 | aldehyde dehydrogenase 6 family, member [NAME] | ALDH6A1 | 1-9 | 0.036977923 | increased | 1.546724187483854 | 32676_at | 603178 | ENSG00000119711 | 293970 | 4329 | NM_005589 | pyrimidine nucleotide metabolism /// valine metabolism /// metabolism | methylmalonate-semialdehyde dehydrogenase (acylating) activity /// oxidoreductase activity /// malonate-semialdehyde dehydrogenase (acetylating) activity | mitochondrion | Inositol metabolism /// [NAME], leucine and isoleucine degradation /// Propanoate metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00031+1.2.1.27 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00280+1.2.1.27 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00640+1.2.1.27
AB023148 | PH domain and leucine rich repeat protein phosphatase-like | PHLPPL | 4-10 | 0.003047087 | increased | 1.575457132946138 | 32735_at | --- | ENSG00000040199 | 531564 | 23035 | NM_015020 | cAMP biosynthesis | magnesium ion binding /// catalytic activity /// lyase activity | --- | --- | ---
AL031432 | GCIP-interacting protein p29 | P29 | 5-3 | 0.000797208 | decreased | 1.754286695961801 | 32792_at | 607090 | ENSG00000117614 | 20013 | 25949 | /// NM_015484 /// NM_207170 | --- | DNA binding /// protein binding | nucleus | --- | ---
AB011177 | ADAMTS-like 2 | ADAMTSL2 | 2-9 | 0.03947535 | increased | 1.358067372088718 | 32866_at | --- | ENSG00000197859 | 522543 | 9719 | NM_014694 | --- | metalloendopeptidase activity /// peptidase activity | extracellular matrix | --- | ---
U88834 | hypothetical protein LOC92558 | LOC92558 | 7-4 | 0.024055089 | decreased | 2.397133692509118 | 32881_at | --- | ENSG00000135127 | 369763 | 92558 | NM_207311 | --- | --- | --- | --- | ---
L09749 | PHD finger protein 20 | PHF20 | 10-3 | 0.014492666 | decreased | 1.455320196712986 | 32884_at | --- | ENSG00000025293 | 517044 | 51230 | [NAME] | transcription /// regulation of transcription, DNA-dependent | nucleic acid binding /// DNA binding /// zinc ion binding | nucleus | --- | ---
AF053356 | HIV-1 Rev binding protein-like | HRBL | 8-3 | 0.030696315 | decreased | 0.85442351206813 | 32894_at | 604019 | ENSG00000106351 | 521083 | 3268 | NM_006076 | regulation of GTPase activity | --- | --- | --- | ---
AL080129 | RAP1 interacting factor homolog (yeast) | RIF1 | 3-3 | 0.020373416 | decreased | 2.336250976854104 | 32922_at | 608952 | ENSG00000080345 | 536537 | 55183 | NM_018151 | --- | ATP binding /// ATPase activity | --- | --- | ---
AL021578 | [NAME] | [NAME] | 6-3 | 0.001246593 | decreased | 1.646642081191398 | 32925_at | 603897 | ENSG00000124159 | 278489 | 8785 | NM_003833 /// NM_030590 /// NM_030592 | extracellular matrix organization and biogenesis | extracellular matrix structural constituent /// calcium ion binding /// collagen binding | extracellular matrix ([NAME]) | --- | ---
AL080068 | GTPase, IMAP family member 5 | GIMAP5 | 8-3 | 0.007868179 | decreased | 1.935842586180147 | 32927_at | 608086 | ENSG00000196329 | 412331 | 55340 | NM_018384 | --- | GTP binding | mitochondrion /// integral to membrane /// outer membrane | --- | ---
AI125131 | [NAME] | [NAME] | 7-3 | 0.003883117 | decreased | 1.674926972585226 | 32938_at | --- | ENSG00000084710 | 227850 | 22979 | XM_039733 | --- | --- | --- | --- | ---
AJ007014 | Alport syndrome, mental retardation, [NAME] and elliptocytosis chromosomal region, gene 1 | AMMECR1 | 2-9 | 0.040536839 | increased | 1.517008810784039 | 32940_at | 300194 /// 300195 | ENSG00000101935 | 211021 | 9949 | NM_015365 | --- | --- | --- | --- | ---
Y12661 | VGF nerve growth factor inducible | VGF | 10-3 | 0.036777721 | decreased | 1.508450129444983 | 32969_r_at | 602186 | ENSG00000128564 | 439672 | 7425 | NM_003378 | --- | growth factor activity | --- | --- | ---
U49187 | chromosome 6 open reading frame 32 | C6orf32 | 2-6 | 0.037309289 | increased | 1.445848221582549 | 32977_at | --- | ENSG00000111913 | 484915 | 9750 | NM_015864 | --- | --- | --- | --- | ---
Z30643 | chloride channel Ka | CLCNKA | 3-3 | 0.042084413 | decreased | 2.002835181215356 | 32988_at | 602024 /// 602522 | ENSG00000186510 | 552570 | 1187 | NM_004070 | ion transport /// chloride transport /// excretion | voltage-gated chloride channel activity | membrane fraction /// integral to plasma membrane /// membrane | --- | ---
U70824 | zinc finger, MYND domain containing 10 | ZMYND10 | 6-2 | 0.027006108 | decreased | 2.450470027044206 | 32993_s_at | 607070 | ENSG00000004838 | 526735 | 51364 | NM_015896 | --- | --- | --- | --- | ---
Y10148 | neurotensin receptor 2 | NTSR2 | 2-6 | 0.010352494 | increased | 1.825511023392846 | 33011_at | 605538 | ENSG00000169006 | 131138 | 23620 | NM_012344 | G-protein coupled receptor protein signaling pathway /// sensory perception | rhodopsin-like receptor activity /// receptor activity /// neurotensin receptor activity, G-protein coupled | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
AF055018 | Family with sequence similarity 55, member C | MGC15606 | 5-3 | 0.011880974 | decreased | 1.698095040829142 | 33042_r_at | --- | ENSG00000144815 | 130195 | 91775 | NM_145037 | --- | --- | --- | --- | ---
D26600 | proteasome (prosome, macropain) subunit, beta type, 4 | PSMB4 | 6-2 | 0.018723043 | decreased | 2.774767192606726 | 33154_at | 602177 | ENSG00000159377 | 89545 | 5692 | NM_002796 | ubiquitin-dependent protein catabolism | threonine endopeptidase activity | proteasome core complex (sensu [NAME]) | Proteasome_Degradation /// Proteasome | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03050+3.4.25.1
L76927 | galactokinase 1 | GALK1 | 6-2 | 0.001155803 | decreased | 1.733602549974126 | 33183_at | 230200 /// 604313 | ENSG00000108479 | 407966 | 2584 | NM_000154 | galactose metabolism /// galactose metabolism /// metabolism /// carbohydrate phosphorylation | galactokinase activity /// galactokinase activity /// ATP binding /// kinase activity /// transferase activity | cytoplasm | Galactose metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00052+2.7.1.6
W27674 | Guanylate cyclase activator 1A (retina) | GUCA1A | 8-3 | 0.026226429 | decreased | 1.154228306292721 | 33184_at | 600364 /// 602093 | ENSG00000048545 | 92858 | 2978 | NM_000409 | signal transduction /// sensory perception /// visual perception | calcium ion binding /// calcium sensitive guanylate cyclase activator activity | --- | --- | ---
HG2573-HT2669 | --- | --- | 5-4 | 0.010196702 | decreased | 2.255294205454345 | 332_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
D38491 | KIAA0117 protein | KIAA0117 | 8-3 | 0.027972974 | decreased | 1.884821153092098 | 33233_at | --- | ENSG00000188739 /// ENSG00000054267 | 535224 | 23029 | NM_015014 | --- | nucleotide binding /// RNA binding | nucleus | --- | ---
AB028996 | myotubularin related protein 2 | MTMR2 | 5-3 | 0.010971968 | decreased | 2.36633262751752 | 33277_at | 601382 /// 603557 | ENSG00000087053 | 181326 | 8898 | NM_016156 /// NM_201278 /// NM_201281 | protein amino acid dephosphorylation /// protein amino acid dephosphorylation /// phospholipid dephosphorylation | inositol or phosphatidylinositol phosphatase activity /// inositol or phosphatidylinositol phosphatase activity /// protein tyrosine phosphatase activity /// protein binding /// protein tyrosine/serine/threonine phosphatase activity /// hydrolase activity | nucleus /// cytoplasm | --- | ---
D63485 | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | IKBKE | 1-6 | 0.020099849 | increased | 1.833689567285503 | 33281_at | 605048 | ENSG00000143466 | 321045 | 9641 | NM_014002 | protein amino acid phosphorylation /// immune response /// positive regulation of I-kappaB kinase/NF-kappaB cascade | protein serine/threonine kinase activity /// NF-kappaB-inducing kinase activity /// signal transducer activity /// ATP binding /// transferase activity | cytoplasm | [NAME] | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
D88827 | zinc finger protein 263 | ZNF263 | 9-2 | 0.003918488 | decreased | 2.029653726517482 | 33289_f_at | 604191 | ENSG00000006194 | 124553 | 10127 | NM_005741 | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// zinc ion binding | nucleus | --- | ---
AF070568 | component of oligomeric golgi complex 7 | COG7 | 5-3 | 0.015725908 | decreased | 1.52575421456686 | 33335_at | 606978 /// 608779 | ENSG00000168434 | 185807 | 91949 | NM_153603 | protein transport | --- | Golgi apparatus /// membrane | --- | ---
AL050028 | putative MAPK activating protein PM20,PM21 | DKFZp566C0424 | 6-2 | 0.014560279 | decreased | 2.064740761608047 | 33395_at | --- | ENSG00000055070 | 252967 | 26099 | NM_015609 | --- | --- | --- | --- | ---
X57398 | NODAL modulator 1 /// NODAL modulator 2 /// NODAL modulator 3 | [NAME] /// NOMO2 /// NOMO3 | 10-3 | 0.018416359 | decreased | 2.827943625998881 | 33414_at | 609157 /// 609158 /// 609159 | ENSG00000103512 /// ENSG00000185164 /// ENSG00000103226 | 209113 | 23420 /// 283820 /// 408050 | NM_001004060 /// NM_001004067 /// NM_014287 /// NM_173614 | aromatic compound metabolism | catalytic activity /// ferric iron binding | --- | --- | ---
AJ000673 | killer cell lectin-like receptor subfamily D, member 1 | [NAME] | 10-3 | 0.031839328 | decreased | 0.7424971535927218 | 33531_at | 602894 | ENSG00000134539 | 524251 | 3824 | NM_002262 /// NM_007334 | cell surface receptor linked signal transduction /// antimicrobial humoral response (sensu Vertebrata) | receptor activity /// transmembrane receptor activity /// sugar binding | plasma membrane /// integral to membrane | --- | ---
[NAME] | zinc finger protein 169 | ZNF169 | 6-3 | 0.007554918 | decreased | 1.487810514781497 | 33566_at | 603404 | ENSG00000175787 | 387623 | 169841 | NM_194320 | transcription /// regulation of transcription, DNA-dependent /// regulation of transcription, DNA-dependent | nucleic acid binding /// transcription factor activity /// zinc ion binding | intracellular /// nucleus /// nucleus | --- | ---
[NAME] | zinc finger protein 46 (KUP) | ZNF46 | 2-9 | 0.020500539 | increased | 1.672091391862394 | 33616_at | 194541 | ENSG00000089775 | 164347 | 7597 | NM_006977 | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// protein binding /// zinc ion binding | nucleus | --- | ---
AI435898 | zinc finger protein 46 (KUP) | ZNF46 | 7-3 | 0.023361678 | decreased | 1.157336477091458 | 33617_s_at | 194541 | ENSG00000089775 | 164347 | 7597 | NM_006977 | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// protein binding /// zinc ion binding | nucleus | --- | ---
Y14768 | allograft inflammatory factor 1 | AIF1 | 10-3 | 0.026278541 | decreased | 1.853453087983154 | 33641_g_at | 601833 | ENSG00000124655 | 76364 | 199 | NM_001623 /// NM_004847 /// NM_032955 | response to stress /// inflammatory response /// cell cycle arrest /// negative regulation of cell proliferation | phosphoprotein phosphatase activity /// calcium ion binding | nucleus | --- | ---
AA224768 | GM2 ganglioside activator | GM2A | 1-7 | 0.015626358 | increased | 1.728522206797144 | 33647_s_at | 272750 | ENSG00000196743 | 483873 | 2760 | NM_000405 | lipid metabolism /// glycosphingolipid metabolism /// glycolipid catabolism /// sphingolipid catabolism | sphingolipid activator protein activity | lysosome | --- | ---
AI431615 | --- | --- | 7-3 | 0.034477339 | decreased | 1.189932361678003 | 33696_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
V01510 | [NAME] (adrenocorticotropin/ beta-lipotropin/ alpha-melanocyte stimulating hormone/ beta-melanocyte stimulating hormone/ beta-endorphin) | POMC | 10-3 | 0.004248691 | decreased | 2.108592975420937 | 33711_at | 176830 | ENSG00000115138 | 1897 | 5443 | NM_000939 | generation of precursor metabolites and energy /// signal transduction /// neuropeptide signaling pathway /// cell-cell signaling | hormone activity | extracellular region /// soluble fraction | --- | ---
M31606 | phosphorylase kinase, gamma 2 (testis) | PHKG2 | 9-3 | 0.033531829 | decreased | 1.181402090634268 | 33745_at | 172471 | [NAME] | 196177 | 5261 | NM_000294 | carbohydrate metabolism /// glycogen biosynthesis /// generation of precursor metabolites and energy /// protein amino acid phosphorylation /// protein amino acid phosphorylation | protein kinase activity /// protein serine/threonine kinase activity /// phosphorylase kinase activity /// phosphorylase kinase activity /// calmodulin binding /// ATP binding /// ATP binding /// transferase activity | phosphorylase kinase complex /// phosphorylase kinase complex | Glycogen_Metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Glycogen_Metabolism/Hs_Glycogen_Metabolism.htm
AB020657 | influenza virus NS1A binding protein | IVNS1ABP | 4-10 | 0.025766103 | increased | 2.087948336860394 | 33752_at | 609209 | ENSG00000116679 | 497183 | 10625 | NM_006469 /// NM_016389 | transcription from RNA polymerase III promoter /// RNA splicing /// response to virus | protein binding | transcription factor complex /// spliceosome complex | --- | ---
X77777 | vasoactive intestinal peptide receptor 1 | VIPR1 | 7-3 | 0.009914469 | decreased | 1.454432266634077 | 33766_at | 192321 | ENSG00000114812 | 348500 | 7433 | NM_004624 | muscle contraction /// immune response /// signal transduction /// G-protein signaling, coupled to cyclic nucleotide second messenger /// synaptic transmission /// digestion /// positive regulation of cell proliferation | receptor activity /// G-protein coupled receptor activity /// vasoactive intestinal polypeptide receptor activity | integral to plasma membrane /// membrane | GPCRDB_Class_B_Secretin-like | [NAME]
Z14229 | nuclear mitotic apparatus protein 1 | NUMA1 | 3-1 | 0.011252092 | decreased | 1.843656297409991 | 33822_at | 164009 | ENSG00000137497 | 523873 | 4926 | NM_006185 | mitotic anaphase /// nuclear organization and biogenesis | structural molecule activity | nucleus /// spindle microtubule | --- | ---
AF011406 | corticotropin releasing hormone receptor 2 | CRHR2 | 2-9 | 0.002159965 | increased | 1.446069273289867 | 33950_g_at | 602034 | ENSG00000106113 | 546246 | 1395 | NM_001883 | signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein signaling, coupled to cAMP nucleotide second messenger | receptor activity /// G-protein coupled receptor activity /// corticotrophin-releasing factor receptor activity | plasma membrane /// integral to plasma membrane | GPCRDB_Class_B_Secretin-like | [NAME]
D10216 | POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1) | POU1F1 | 8-3 | 0.028562613 | decreased | 1.471445694541636 | 34014_f_at | 173110 | ENSG00000064835 | 89394 | 5449 | NM_000306 | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// negative regulation of cell proliferation /// organogenesis | transcription factor activity | nucleus | --- | ---
U79295 | Clone 23961 mRNA sequence | --- | 8-3 | 0.002083743 | decreased | 1.623694555483298 | 34026_at | --- | --- | 90866 | --- | --- | --- | --- | --- | --- | ---
W28667 | Chromosome 9 open reading frame 38 | UHRF2 | 8-3 | 0.026708121 | decreased | 1.962178152086188 | 34036_at | --- | ENSG00000147854 | 493401 | 115426 | NM_152306 /// NM_152896 | regulation of transcription, DNA-dependent /// protein modification /// protein ubiquitination | DNA binding /// ubiquitin-protein ligase activity /// zinc ion binding | ubiquitin ligase complex | --- | ---
U96769 | chondroadherin | CHAD | 6-2 | 0.011124098 | decreased | 1.665617555211184 | 34042_at | 602178 | ENSG00000136457 | 97220 | 1101 | NM_001267 | regulation of cell growth | extracellular matrix structural constituent | extracellular matrix ([NAME]) | --- | ---
Z83844 | SH3-domain binding protein 1 | SH3BP1 | 10-3 | 0.019032559 | decreased | 1.356868096999813 | 34046_at | --- | ENSG00000100092 | 407909 | 23616 | NM_018957 | --- | GTPase activator activity /// protein binding | cytoplasm | --- | ---
AJ012371 | N-acetylated alpha-linked acidic dipeptidase-like 1 | NAALADL1 | 6-2 | 0.03515379 | decreased | 3.453625259322806 | 34080_at | 602640 | ENSG00000168060 | 13967 | 10004 | NM_005468 | proteolysis and peptidolysis | carboxypeptidase activity /// metallopeptidase activity /// dipeptidase activity /// glutamate carboxypeptidase II activity | integral to membrane | --- | ---
Z97184 | --- | --- | 7-3 | 0.026576832 | decreased | 2.041525579820794 | 34090_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
AB023223 | syntaxin binding protein 5-like | STXBP5L | 7-3 | 0.03846123 | decreased | 1.862975260545553 | 34129_at | --- | ENSG00000145087 | 477315 | 9515 | XM_045911 | vesicle-mediated transport | --- | integral to membrane | --- | ---
AL050185 | --- | --- | 7-3 | 0.008110307 | decreased | 2.115207019166089 | 34135_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
M63241 | tyrosinase (oculocutaneous albinism IA) | TYR | 10-3 | 0.038647186 | decreased | 1.151588885158956 | 34155_s_at | 103470 /// 203100 /// 606933 /// 606952 | ENSG00000077498 | 503555 | 7299 | NM_000372 | melanin biosynthesis from tyrosine /// eye pigment biosynthesis /// visual perception /// perception of sound /// metabolism | monooxygenase activity /// monophenol monooxygenase activity | Golgi vesicle /// integral to membrane | Tyrosine metabolism /// [NAME] metabolism /// Stilbene, coumarine and lignin biosynthesis /// Alkaloid biosynthesis I | www.genome.ad.jp/dbget-bin/show_pathway?MAP00350+1.14.18.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00740+1.14.18.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00940+1.14.18.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00950+1.14.18.1
AB013802 | contactin 5 | CNTN5 | 8-3 | 0.040106865 | decreased | 1.73822194494323 | 34173_s_at | 607219 | ENSG00000149972 | 268707 | 53942 | NM_014361 /// NM_175566 | cell adhesion | protein binding | membrane | --- | ---
[NAME] | SET domain, bifurcated 1 | SETDB1 | 10-3 | 0.010245814 | decreased | 1.78432476718947 | 34189_at | 604396 | ENSG00000143379 | 516278 | 9869 | NM_012432 | chromatin modification | DNA binding /// methyltransferase activity /// zinc ion binding /// transferase activity /// histone-lysine N-methyltransferase activity | nucleus | --- | ---
AF006740 | coagulation factor C homolog, [NAME] (Limulus polyphemus) | COCH | 2-9 | 0.012529522 | increased | 1.319799088416989 | 34190_at | 601369 /// 603196 | ENSG00000100473 | 21016 | 1690 | NM_004086 | perception of sound | --- | --- | --- | ---
AL049786 | hypothetical gene CG018 | CG018 | 2-10 | 0.003225781 | increased | 1.561159544978217 | 34240_s_at | --- | ENSG00000139597 | 161220 | 90634 | NM_052818 | --- | --- | --- | --- | ---
AI810767 | Protease, serine, 12 (neurotrypsin, motopsin) | PRSS12 | 8-3 | 0.023030072 | decreased | 1.274138275564306 | 34247_at | 249500 /// 606709 | ENSG00000164099 | 445857 | 8492 | NM_003619 | proteolysis and peptidolysis | chymotrypsin activity /// trypsin activity /// protein-lysine 6-oxidase activity /// scavenger receptor activity /// copper ion binding | membrane | --- | ---
U14417 | ral guanine nucleotide dissociation stimulator | RALGDS | 9-4 | 0.010731676 | decreased | 1.2858626348473 | 34254_at | 601619 | ENSG00000160271 | 106185 | 5900 | NM_006266 | small GTPase mediated signal transduction /// small GTPase mediated signal transduction | guanyl-nucleotide exchange factor activity | --- | --- | ---
U50748 | [NAME] receptor | LEPR | 1-7 | 0.042996902 | increased | 2.54615966588646 | 34267_r_at | 601007 | ENSG00000116678 | 23581 | 3953 | NM_001003679 /// NM_001003680 /// NM_002303 | energy reserve metabolism /// cell surface receptor linked signal transduction /// development | [NAME]/interferon-class (D200-domain) cytokine receptor activity | integral to plasma membrane /// membrane | --- | ---
Z19574 | keratin 17 | KRT17 | 6-2 | 0.038539121 | decreased | 1.900739358456855 | 34301_r_at | 148069 /// 167210 /// 184500 | ENSG00000186831 | 2785 | 3872 | NM_000422 | epidermis development | structural molecule activity /// structural constituent of cytoskeleton | intermediate filament /// intermediate filament | --- | ---
W52024 | ribosomal protein S15a | RPS15A | 3-3 | 0.007687434 | decreased | 1.748661269220334 | 34316_at | 603674 | ENSG00000134419 | 370504 | 6210 | NM_001019 | protein biosynthesis | structural constituent of ribosome | ribosome | --- | ---
D31766 | glucosamine-6-phosphate deaminase 1 | GNPDA1 | 10-3 | 0.031262006 | decreased | 1.35132433817363 | 34332_at | 601798 | ENSG00000113552 | 278500 | 10007 | NM_005471 | carbohydrate metabolism /// glucosamine catabolism /// N-acetylglucosamine metabolism /// generation of precursor metabolites and energy /// fertilization (sensu Metazoa) | glucosamine-6-phosphate deaminase activity /// hydrolase activity | --- | --- | ---
Z22536 | activin A receptor, type IB | ACVR1B | 2-9 | 0.020537495 | increased | 1.502394032311496 | 34415_at | 601300 | ENSG00000135503 | 438918 | 91 | NM_004302 /// NM_020327 /// NM_020328 | protein amino acid phosphorylation /// transmembrane receptor protein serine/threonine kinase signaling pathway | protein serine/threonine kinase activity /// receptor activity /// transforming growth factor beta receptor activity /// ATP binding /// transferase activity | integral to plasma membrane /// membrane | Phosphatidylinositol signaling system | www.genome.ad.jp/dbget-bin/show_pathway?MAP04070+2.7.1.37
[NAME] | D-amino-acid oxidase | DAO | 3-1 | 0.019829375 | decreased | 1.26383071549727 | 34464_at | 124050 /// 181500 | ENSG00000110887 | 113227 | 1610 | NM_001917 | electron transport | D-amino-acid oxidase activity /// electron transporter activity /// oxidoreductase activity | peroxisome | Glycine, serine and threonine metabolism /// Arginine and proline metabolism /// D-Arginine and D-ornithine metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00260+1.4.3.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00330+1.4.3.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00472+1.4.3.3
AF030227 | vav 1 oncogene | [NAME] | 3-3 | 0.016096714 | decreased | 2.19039307339202 | 34481_at | 164875 | ENSG00000141968 | 116237 | 7409 | NM_005428 | intracellular signaling cascade | transcription factor activity /// guanyl-nucleotide exchange factor activity /// diacylglycerol binding | nucleus | --- | ---
AI022655 | --- | --- | 9-3 | 0.015742072 | decreased | 1.389844764391719 | 34487_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
U20530 | secreted phosphoprotein 2, 24kDa | SPP2 | 5-3 | 0.031659075 | decreased | 1.893566728693576 | 34504_at | 602637 | [NAME] | 444488 | 6694 | NM_006944 | skeletal development /// bone remodeling | endopeptidase inhibitor activity | extracellular space | --- | ---
M13928 | aminolevulinate, delta-, dehydratase | ALAD | 2-9 | 0.013451017 | increased | 1.946937294692673 | 34506_at | 125270 | ENSG00000148218 | 1227 | 210 | NM_000031 /// NM_001003945 | heme biosynthesis /// heme biosynthesis | porphobilinogen synthase activity /// porphobilinogen synthase activity /// lyase activity | --- | Heme_Biosynthesis /// [NAME] and chlorophyll metabolism | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00860+4.2.1.24
L25119 | opioid receptor, mu 1 | OPRM1 | 2-9 | 0.029092772 | increased | 2.545309478866343 | 34534_at | 600018 | ENSG00000112038 | 2353 | 4988 | NM_000914 /// NM_001008503 /// NM_001008504 /// NM_001008505 | signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein signaling, coupled to cyclic nucleotide second messenger /// sensory perception /// behavior /// negative regulation of cell proliferation | rhodopsin-like receptor activity /// receptor activity /// mu-opioid receptor activity /// mu-opioid receptor activity | endoplasmic reticulum /// Golgi apparatus /// plasma membrane /// integral to plasma membrane /// integral to membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
X67594 | melanocortin 1 receptor ([NAME] stimulating hormone receptor) | MC1R | 6-2 | 0.019545595 | decreased | 1.723511175730655 | 34557_at | 155555 | [NAME] | 513829 | 4157 | NM_002386 | signal transduction /// G-protein signaling, coupled to cyclic nucleotide second messenger /// development /// UV protection | rhodopsin-like receptor activity /// receptor activity /// melanocyte stimulating hormone receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
[NAME] | [NAME] (mouse) | TUB | 2-9 | 0.040886493 | increased | 1.433668161678383 | 34599_at | 601197 | ENSG00000166402 | 231850 | 7275 | NM_003320 /// NM_177972 | --- | --- | nucleus /// cytoplasm | --- | ---
U57796 | zinc finger protein 192 | ZNF192 | 7-4 | 0.006970913 | decreased | 2.285841852897921 | 34611_at | 602240 | ENSG00000198315 | 57679 | 7745 | NM_006298 | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// protein binding /// zinc ion binding | nucleus | --- | ---
AB029009 | KIAA1086 | KIAA1086 | 5-4 | 0.004503413 | decreased | 2.831097892371317 | 34613_at | --- | ENSG00000105278 | 65750 | 23217 | XM_047610 | --- | nucleic acid binding /// zinc ion binding | nucleus | --- | ---
U15422 | protamine 2 | PRM2 | 7-4 | 0.02896416 | decreased | 0.7484464778569219 | 34658_at | 182890 | ENSG00000122304 | 2324 | 5620 | NM_002762 | DNA packaging /// chromosome organization and biogenesis (sensu [NAME]) /// mitotic chromosome condensation /// spermatogenesis /// cell differentiation | DNA binding | nucleosome /// nucleoplasm /// chromosome | --- | ---
AA151971 | HERV-H LTR-associating 1 | HHLA1 | 1-7 | 0.033667024 | increased | 2.045120022719468 | 34704_r_at | 604109 | ENSG00000104386 | 285026 | 10086 | NM_005712 | --- | --- | --- | --- | ---
AB002357 | [NAME] member 3B | KIF3B | 5-3 | 0.040919721 | decreased | 2.855797319813054 | 34713_at | 603754 | ENSG00000101350 | 369670 | 9371 | NM_004798 | microtubule-based movement /// determination of left/right symmetry /// anterograde axon cargo transport | ATP binding /// plus-end-directed microtubule motor activity | plus-end kinesin complex /// microtubule associated complex | --- | ---
X83535 | matrix metalloproteinase 14 (membrane-inserted) | MMP14 | 5-3 | 0.0338295 | decreased | 5.028176166016088 | 34747_at | 600754 | ENSG00000157227 | 2399 | 4323 | NM_004995 | proteolysis and peptidolysis | metalloendopeptidase activity /// zinc ion binding | extracellular matrix (sensu Metazoa) /// integral to plasma membrane | Matrix_Metalloproteinases | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Matrix_Metalloproteinases/Hs_Matrix_Metalloproteinases.htm
AB020653 | RAS guanyl releasing protein 3 (calcium and DAG-regulated) | [NAME] | 10-3 | 0.009936323 | decreased | 2.37589881653208 | 34748_at | --- | ENSG00000152689 | 143674 | 25780 | NM_170672 | MAPKKK cascade /// small GTPase mediated signal transduction | signal transducer activity /// guanyl-nucleotide exchange factor activity /// calcium ion binding /// protein binding /// diacylglycerol binding /// [NAME] activator activity | integral to plasma membrane | --- | ---
X96381 | ets variant gene 5 (ets-related molecule) | ETV5 | 8-2 | 0.021976742 | decreased | 2.601889953666074 | 34818_at | 601600 | ENSG00000171656 | 43697 | 2119 | NM_004454 | regulation of transcription, DNA-dependent | transcription factor activity | nucleus | --- | ---
AC003965 | protease, serine, 22 | PRSS22 | 2-6 | 0.04251957 | increased | 1.410570036531618 | 34894_r_at | 609343 | ENSG00000005001 | 459709 | 64063 | NM_022119 | proteolysis and peptidolysis | chymotrypsin activity /// trypsin activity /// peptidase activity | --- | --- | ---
AL049329 | hypothetical protein FLJ13946 | FLJ13946 | 7-4 | 0.020089665 | decreased | 2.100664554848786 | 34908_at | --- | ENSG00000196659 | 128384 | 92104 | NM_152275 | --- | binding | --- | --- | ---
AC004990 | putative homeodomain transcription factor 2 | PHTF2 | 7-3 | 0.034540057 | decreased | 2.467126936597309 | 34909_at | --- | ENSG00000006576 | 203965 | 57157 | NM_020432 | --- | --- | --- | --- | ---
AF052140 | Hypothetical gene supported by BC040718 | --- | 9-3 | 0.023762899 | decreased | 1.10256834430536 | 34958_at | --- | --- | 141055 | 388458 | XM_371106 | --- | --- | --- | --- | ---
AF001549 | similar to RNA polymerase I transcription factor RRN3 | LOC94431 | 7-4 | 0.043716407 | decreased | 1.541736060969568 | 34967_at | --- | ENSG00000179038 | 546468 | 94431 | NM_145237 | --- | --- | --- | --- | ---
AB022660 | SET binding protein 1 | SETBP1 | 6-2 | 0.021093731 | decreased | 2.248028594474785 | 34990_at | --- | ENSG00000152217 | 435458 | 26040 | NM_015559 | --- | DNA binding | nucleus | --- | ---
U62966 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 | SLC28A1 | 8-2 | 0.025447177 | decreased | 1.51088541656822 | 35037_at | 606207 | ENSG00000156222 | 459187 | 9154 | NM_004213 /// NM_201651 | nucleobase, nucleoside, nucleotide and nucleic acid metabolism /// transport /// nucleoside transport | nucleoside binding /// nucleoside transporter activity /// nucleoside:sodium symporter activity | membrane fraction /// integral to plasma membrane /// membrane | --- | ---
AL109705 | KIAA0256 gene product | KIAA0256 | 8-3 | 0.039359055 | decreased | 1.504845797920209 | 35046_at | --- | ENSG00000138593 | 9997 | 9728 | NM_014701 | --- | --- | --- | --- | ---
AC005784 | regulatory factor X, 2 (influences HLA class II expression) | RFX2 | 4-10 | 0.006864298 | increased | 1.919359913681245 | 35047_at | 142765 | ENSG00000087903 | 465709 | 5990 | NM_000635 /// NM_134433 | regulation of transcription, DNA-dependent | DNA binding /// DNA binding /// RNA polymerase II transcription factor activity /// transcription regulator activity | nucleus /// nucleus | --- | ---
AB002339 | Nedd4 binding protein 3 | N4BP3 | 3-3 | 0.015077578 | decreased | 1.828120111391315 | 35057_at | --- | ENSG00000145911 | 101761 | 23138 | NM_015111 | --- | --- | cytoplasm /// membrane | --- | ---
AI571208 | RNA pseudouridylate synthase domain containing 2 | RPUSD2 | 9-1 | 0.036696675 | decreased | 1.039540209733272 | 35075_at | --- | ENSG00000166133 | 173311 | 27079 | NM_152260 | RNA processing | RNA binding /// pseudouridylate synthase activity /// pseudouridine synthase activity | --- | --- | ---
D14838 | fibroblast growth factor 9 (glia-activating factor) | FGF9 | 6-2 | 0.021958545 | decreased | 1.74654046159689 | 35081_at | 600921 | ENSG00000102678 | 111 | 2254 | NM_002010 | regulation of cell cycle /// signal transduction /// cell-cell signaling /// cell proliferation /// cell differentiation | growth factor activity /// heparin binding | extracellular space | --- | ---
D49919 | chemokine (C-C motif) receptor 8 | CCR8 | 8-3 | 0.031145445 | decreased | 1.037361343208933 | 35088_at | 601834 | ENSG00000179934 | 113222 | 1237 | NM_005201 | chemotaxis /// immune response /// cell adhesion /// signal transduction /// G-protein coupled receptor protein signaling pathway /// positive regulation of cytosolic calcium ion concentration | rhodopsin-like receptor activity /// coreceptor activity /// C-C chemokine receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
W27417 | M-phase phosphoprotein, mpp8 | HSMPP8 | 5-2 | 0.012336985 | decreased | 1.490380577906763 | 35110_at | --- | ENSG00000196199 | 549166 | 54737 | NM_017520 | chromatin assembly or disassembly /// cell cycle | chromatin binding | chromatin /// nucleus /// nucleus /// cytoplasm | --- | ---
[NAME] | ornithine carbamoyltransferase | OTC | 7-4 | 0.029609851 | decreased | 2.357457734272266 | 35111_at | 300461 /// 311250 | ENSG00000036473 | 117050 | 5009 | NM_000531 | urea cycle /// 'de novo' pyrimidine base biosynthesis /// arginine biosynthesis /// amino acid biosynthesis | aspartate carbamoyltransferase activity /// ornithine carbamoyltransferase activity /// amino acid binding /// transferase activity | mitochondrial matrix /// ornithine carbamoyltransferase complex | Urea cycle and metabolism of amino groups /// Arginine and proline metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00220+2.1.3.3 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00330+2.1.3.3
[NAME] | solute carrier family 22 (organic cation transporter), member 1 | SLC22A1 | 3-3 | 0.042658818 | decreased | 3.607957812690487 | 35113_at | 602607 | ENSG00000175003 | 117367 | 6580 | NM_003057 /// NM_153187 | ion transport /// sodium ion transport /// organic cation transport | ATP binding /// ion transporter activity /// organic cation transporter activity /// symporter activity | membrane fraction /// integral to plasma membrane /// membrane /// integral to membrane | --- | ---
X69090 | [NAME] (skelemin) 185kDa | MYOM1 | 8-3 | 0.015410645 | decreased | 2.11632612928188 | 35137_at | 603508 | ENSG00000101605 | 464469 | 8736 | NM_003803 | striated muscle contraction /// striated muscle contraction /// muscle development | structural constituent of muscle | striated muscle thick filament /// myofibril | Striated_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Striated_muscle_contraction/Hs_Striated_muscle_contraction.htm
AB009598 | beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I) | B3GAT3 | 5-3 | 0.032749637 | decreased | 1.877435549557507 | 35179_at | 606374 | ENSG00000149541 | 502759 | 26229 | NM_012200 | glycosaminoglycan biosynthesis | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity /// galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity /// transferase activity /// manganese ion binding | Golgi membrane /// membrane /// integral to membrane | Chondroitin / Heparan sulfate biosynthesis | www.genome.ad.jp/dbget-bin/show_pathway?MAP00532+2.4.1.135
W25874 | septin 11 | 2005-09-11 00:00:00 | 7-3 | 0.041341669 | decreased | 1.399931442317168 | 35182_f_at | --- | ENSG00000138758 | 128199 | 55752 | NM_018243 | cytokinesis /// cell cycle | GTP binding | --- | --- | ---
AB018336 | FERM, [NAME] and pleckstrin domain protein 2 | FARP2 | 3-3 | 0.01702492 | decreased | 1.68134518410946 | 35188_at | --- | ENSG00000006607 | 552580 | 9855 | NM_014808 | --- | cytoskeletal protein binding | cytoplasm /// cytoskeleton /// membrane | --- | ---
D30036 | phosphatidylinositol transfer protein, alpha | PITPNA | 8-3 | 0.042550409 | decreased | 1.188672725883517 | 352_at | 600174 | ENSG00000174238 | 429819 | 5306 | NM_006224 | lipid metabolism /// transport /// visual perception | lipid binding /// phosphatidylcholine transporter activity /// phosphatidylinositol transporter activity | intracellular | --- | ---
X16135 | heterogeneous nuclear ribonucleoprotein L | HNRPL | 1-7 | 0.010043443 | increased | 1.837386338026871 | 35201_at | 603083 | ENSG00000104824 | 446623 | 3191 | NM_001005335 /// NM_001533 | mRNA processing | nucleotide binding /// [NAME] binding /// RNA binding | nucleus /// nucleoplasm /// heterogeneous nuclear ribonucleoprotein complex | mRNA_processing_Reactome | [NAME]
AF049105 | centrosomal protein 2 | CEP2 | 3-1 | 0.019022244 | decreased | 1.690787708386409 | 35206_at | --- | ENSG00000126001 | 443976 | 11190 | NM_007186 | mitotic cell cycle /// regulation of centriole-centriole cohesion | protein kinase binding | centrosome | --- | ---
AB018296 | KIAA0753 gene product | KIAA0753 | 8-3 | 0.042462548 | decreased | 2.86366150385299 | 35210_at | --- | ENSG00000198920 | 28070 | 9851 | NM_014804 | --- | --- | --- | --- | ---
M91592 | zinc finger protein 76 (expressed in testis) | ZNF76 | 7-3 | 0.000224087 | decreased | 1.679997939718743 | 35225_at | 194549 | ENSG00000065029 | 388024 | 7629 | NM_003427 | transcription /// regulation of transcription from RNA polymerase II promoter /// regulation of transcription from RNA polymerase III promoter | DNA binding /// zinc ion binding | nucleus | --- | ---
X86810 | emerin (Emery-Dreifuss muscular dystrophy) | EMD | 3-3 | 0.01494712 | decreased | 1.769796886469728 | 35239_at | 300384 /// 310300 | ENSG00000102119 | 522823 | 2010 | NM_000117 | muscle contraction /// muscle development | --- | nuclear membrane /// integral to membrane | --- | ---
AB020674 | Mlx interactor | MONDOA | 6-1 | 0.024124302 | decreased | 2.231489784546821 | 35260_at | 608090 | ENSG00000175727 | 437153 | 22877 | NM_014938 | --- | --- | --- | --- | ---
W07033 | glia maturation factor, gamma | GMFG | 10-3 | 0.040980596 | decreased | 1.63514336810403 | 35261_at | 604104 | ENSG00000130755 | 5210 | 9535 | NM_004877 | protein amino acid phosphorylation | [NAME] binding /// protein kinase inhibitor activity /// enzyme activator activity /// growth factor activity | intracellular | --- | ---
AF093420 | hsp70-interacting protein | HSPBP1 | 3-3 | 0.015633938 | decreased | 1.685699663519314 | 35269_at | --- | ENSG00000133265 | 53066 | 23640 | NM_012267 | protein folding /// response to unfolded protein | enzyme inhibitor activity /// binding | --- | --- | ---
[NAME] | Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro) | SSA2 | 4-9 | 0.015228243 | increased | 3.255952874472389 | 35293_at | 600063 | ENSG00000116747 | 288178 | 6738 | NM_004600 | transcription from RNA polymerase III promoter | RNA binding | ribonucleoprotein complex | --- | ---
U96876 | insulin induced gene 1 | INSIG1 | 4-10 | 0.005417244 | increased | 2.062125967350148 | 35303_at | 602055 | [NAME] | 520819 | 3638 | NM_005542 /// NM_198336 /// NM_198337 | metabolism /// cell proliferation | --- | integral to membrane | --- | ---
AB002308 | KIAA0310 | KIAA0310 | 10-3 | 0.04309015 | decreased | 1.709614799136564 | 35313_at | --- | ENSG00000148396 | 522500 | 9919 | XM_088459 | --- | --- | --- | --- | ---
U25435 | CCCTC-binding factor (zinc finger protein) | CTCF | 10-3 | 0.036311116 | decreased | 2.346419301678921 | 35319_at | 604167 | ENSG00000102974 | 368367 | 10664 | NM_006565 | negative regulation of transcription from RNA polymerase II promoter /// transcription /// negative regulation of cell cycle /// positive regulation of transcription, DNA-dependent | transcription factor activity /// RNA polymerase II transcription factor activity /// transcription corepressor activity /// zinc ion binding | nucleus | --- | ---
D50922 | kelch-like ECH-associated protein 1 | KEAP1 | 5-3 | 0.031952683 | decreased | 1.700481601424533 | 35322_at | 606016 | ENSG00000079999 | 465870 | 9817 | NM_012289 /// NM_203500 | transcription /// regulation of transcription, DNA-dependent | protein binding | --- | --- | ---
U94357 | glycogenin 2 | GYG2 | 4-10 | 0.041978628 | increased | 2.20618622592854 | 35334_at | 300198 | ENSG00000056998 | 541209 | 8908 | NM_003918 | glycogen biosynthesis /// carbohydrate biosynthesis | glycogenin glucosyltransferase activity /// transferase activity /// transferase activity, transferring hexosyl groups | soluble fraction | Glycogen_Metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Glycogen_Metabolism/Hs_Glycogen_Metabolism.htm
AB020665 | LIM domain 7 | LMO7 | 4-9 | 0.010175703 | increased | 2.582858315450486 | 35344_at | 604362 | ENSG00000136153 | 207631 | 4008 | NM_005358 | protein ubiquitination | ubiquitin-protein ligase activity /// protein binding /// zinc ion binding | ubiquitin ligase complex /// nucleus /// cytoplasm | --- | ---
M28130 | interleukin 8 | IL8 | 2-9 | 0.014382031 | increased | 1.308768688153203 | 35372_r_at | 146930 | ENSG00000169429 | 624 | 3576 | NM_000584 | angiogenesis /// cell motility /// chemotaxis /// cell cycle arrest /// G-protein coupled receptor protein signaling pathway /// intracellular signaling cascade /// cell-cell signaling /// sensory perception /// negative regulation of cell proliferation /// calcium-mediated signaling /// regulation of cell adhesion /// neutrophil chemotaxis /// neutrophil activation /// regulation of retroviral genome replication /// induction of positive chemotaxis | interleukin-8 receptor binding /// protein binding /// chemokine activity | extracellular space /// soluble fraction | --- | ---
X54412 | collagen, type IX, alpha 1 | COL9A1 | 9-3 | 0.032093127 | decreased | 1.368985371634051 | 35379_at | 120210 | ENSG00000112280 | 149809 | 1297 | NM_001851 /// NM_078485 | phosphate transport /// organogenesis | extracellular matrix structural constituent | extracellular matrix (sensu Metazoa) /// collagen type IX /// cytoplasm | --- | ---
AI816796 | hypothetical protein DKFZp586M1120 | DKFZP586M1120 | 2-9 | 0.01441606 | increased | 1.155955784687897 | 35429_at | --- | ENSG00000171962 | 528889 | 83450 | NM_031294 | --- | --- | --- | --- | ---
AL109690 | SCAN domain containing 2 | SCAND2 | 10-3 | 0.036116211 | decreased | 2.054299143051827 | 35452_at | --- | ENSG00000176700 | 513102 | 54581 | NM_022050 /// NM_033633 /// NM_033634 /// NM_033635 /// NM_033636 /// NM_033640 | regulation of transcription, DNA-dependent | transcription factor activity | nucleus | --- | ---
U59111 | dermatan sulfate proteoglycan 3 | DSPG3 | 2-9 | 0.042706058 | increased | 2.034908201031721 | 35453_at | 601657 | ENSG00000083782 | 435680 | 1833 | NM_004950 | pregnancy | glycosaminoglycan binding | extracellular matrix ([NAME]) | --- | ---
AF059734 | [NAME] (expressed in ES cells) 1 | HESX1 | 7-3 | 0.019955521 | decreased | 1.899716326574394 | 35463_at | 182230 /// 601802 | ENSG00000163666 | 171980 | 8820 | NM_003865 | regulation of transcription, DNA-dependent /// development /// brain development | transcription factor activity | nucleus | --- | ---
U29700 | anti-Mullerian hormone receptor, type II | AMHR2 | 6-2 | 0.034884908 | decreased | 2.950953111867536 | 35502_at | 261550 /// 600956 | ENSG00000135409 | 437877 | 269 | NM_020547 | Mullerian duct regression /// protein amino acid phosphorylation /// signal transduction /// sex determination /// sex differentiation /// sex differentiation | protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// receptor activity /// receptor activity /// transforming growth factor beta receptor activity /// transmembrane receptor protein serine/threonine kinase signaling protein activity /// ATP binding /// transferase activity /// hormone binding | membrane /// integral to membrane | --- | ---
AL109667 | KIAA1199 | KIAA1199 | 5-3 | 0.00241469 | decreased | 1.701435342792816 | 35509_at | 608366 | ENSG00000103888 | 459088 | 57214 | NM_018689 | perception of sound | --- | --- | --- | ---
AF024578 | protein phosphatase 1, regulatory (inhibitor) subunit 3A (glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle) | [NAME] | 10-3 | 0.042434565 | decreased | 1.020962678461176 | 35518_at | 600917 /// 604367 | ENSG00000154415 | 458309 | 5506 | NM_002711 | carbohydrate metabolism /// glycogen metabolism | phosphoprotein phosphatase activity /// type 1 serine/threonine specific protein phosphatase inhibitor activity /// hydrolase activity | integral to membrane | --- | ---
AJ130941 | claudin 9 | CLDN9 | 2-9 | 0.020666098 | increased | 1.347608037907516 | 35521_at | --- | ENSG00000178709 | 296949 | 9080 | NM_020982 | calcium-independent cell-cell adhesion | structural molecule activity /// protein self binding | tight junction /// membrane /// integral to membrane | --- | ---
AB020593 | phosphodiesterase 10A | PDE10A | 2-9 | 0.037411886 | increased | 0.9389921906632899 | 35522_at | --- | ENSG00000112541 | 487129 | 10846 | NM_006661 | signal transduction | nucleotide binding /// 3',5'-cyclic-nucleotide phosphodiesterase activity /// hydrolase activity /// 3',5'-cGMP binding | --- | --- | ---
[NAME] | [NAME] syndrome protein interacting protein | WASPIP | 4-9 | 0.036465805 | increased | 1.27332191787773 | 35528_at | 602357 | ENSG00000115935 | 128067 | 7456 | NM_003387 | protein complex assembly /// actin polymerization and/or depolymerization | [NAME] binding /// profilin binding | [NAME] | --- | ---
AB000824 | trehalase (brush-border membrane glycoprotein) | TREH | 9-3 | 0.01753449 | decreased | 1.252047021144755 | 35529_at | 275360 | ENSG00000118094 | 129712 | 11181 | NM_007180 | carbohydrate metabolism /// trehalose catabolism | alpha,alpha-trehalase activity /// hydrolase activity, acting on glycosyl bonds | plasma membrane /// anchored to plasma membrane | --- | ---
AB007975 | KIAA0506 protein | KIAA0506 | 8-3 | 0.024612901 | decreased | 1.793791076152464 | 35541_r_at | --- | --- | --- | 57239 | --- | --- | --- | --- | --- | ---
AI041180 | phosphate cytidylyltransferase 1, choline, beta isoform | PCYT1B | 5-2 | 0.01502064 | decreased | 3.492509988666256 | 35552_at | 604926 | ENSG00000102230 | 132794 | 9468 | NM_004845 | phosphatidylcholine biosynthesis /// phospholipid biosynthesis /// biosynthesis | choline-phosphate cytidylyltransferase activity /// transferase activity | endoplasmic reticulum | --- | ---
K02402 | coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B) | F9 | 10-3 | 0.04147751 | decreased | 1.100001092545259 | 35556_at | 306900 | ENSG00000101981 | 522798 | 2158 | NM_000133 | proteolysis and peptidolysis /// blood coagulation | coagulation factor IXa activity /// chymotrypsin activity /// trypsin activity /// calcium ion binding /// peptidase activity | extracellular region | Blood_Clotting_Cascade | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Blood_Clotting_Cascade/Hs_Blood_Clotting_Cascade.htm
M62397 | mutated in colorectal cancers | MCC | 6-3 | 0.020572233 | decreased | 2.136221694863359 | 35561_at | 159350 | ENSG00000171444 | 483104 | 4163 | NM_002387 | cell cycle /// signal transduction /// negative regulation of cell cycle | receptor activity /// calcium ion binding | --- | --- | ---
AF027866 | serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7 | SERPINB7 | 6-2 | 0.019699924 | decreased | 1.757300717846163 | 35577_at | 603357 | ENSG00000166396 | 138202 | 8710 | NM_003784 | --- | serine-type endopeptidase inhibitor activity | --- | --- | ---
AB011414 | zinc finger protein HIT-40 | HIT-40 | 8-3 | 0.004837168 | decreased | 1.351428426907769 | 35588_at | --- | --- | --- | 90576 | --- | --- | nucleic acid binding /// zinc ion binding | nucleus | --- | ---
AL049938 | chromosome 10 open reading frame 12 | C10orf12 | 4-9 | 0.001321009 | increased | 2.29085244101303 | 35612_at | --- | ENSG00000155640 | 14555 | 26148 | NM_015652 | --- | --- | --- | --- | ---
AL031652 | phospholipase C, beta 4 | PLCB4 | 9-1 | 0.028132249 | decreased | 1.225553389886289 | 35654_at | 600810 | ENSG00000101333 | 472101 | 5332 | NM_000933 /// NM_182797 | lipid metabolism /// intracellular signaling cascade /// lipid catabolism | phosphoinositide phospholipase C activity /// signal transducer activity /// calcium ion binding /// hydrolase activity | --- | Inositol phosphate metabolism /// Phosphatidylinositol signaling system | www.genome.ad.jp/dbget-bin/show_pathway?MAP00562+3.1.4.11 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP04070+3.1.4.11
U20536 | caspase 6, apoptosis-related cysteine protease | CASP6 | 8-3 | 0.041136121 | decreased | 1.592910493957003 | 35662_at | 601532 | ENSG00000138794 | 3280 | 839 | NM_001226 /// NM_032992 | proteolysis and peptidolysis /// apoptosis /// induction of apoptosis | cysteine-type peptidase activity /// caspase activity | --- | Apoptosis /// Apoptosis_GenMAPP /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_GenMAPP/Hs_Apoptosis_GenMAPP.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
U79569 | cleavage and polyadenylation specific factor 4, 30kDa | CPSF4 | 1-7 | 0.018240663 | increased | 1.766476795827135 | 35743_at | 603052 | ENSG00000160917 | 489287 | 10898 | NM_006693 | mRNA processing | RNA binding | nucleus | mRNA_processing_Reactome | [NAME]
Y17169 | PTK9L protein tyrosine kinase 9-like (A6-related protein) | PTK9L | 3-2 | 0.009427326 | decreased | 1.995525957480791 | 35796_at | 607433 | ENSG00000173366 | 436439 | 11344 | NM_007284 | --- | [NAME] binding /// actin binding /// ATP binding | intracellular | --- | ---
AL080181 | Immunoglobulin superfamily, member 4 | IGSF4 | 2-9 | 0.01383367 | increased | 1.829462678821401 | 35829_at | 605686 | ENSG00000182985 | 370510 | 23705 | NM_014333 | --- | --- | --- | --- | ---
M24899 | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | THRA | 3-2 | 0.000983574 | decreased | 1.784558973412569 | 35846_at | 190120 | ENSG00000126351 | 724 | 7067 | NM_003250 /// NM_199334 | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter | transcription factor activity /// steroid hormone receptor activity /// thyroid hormone receptor activity | nucleus | Nuclear_Receptors | [NAME]
S78203 | solute carrier family 15 (H+/peptide transporter), member 2 | SLC15A2 | 9-1 | 0.015067018 | decreased | 1.41170081925737 | 35862_at | 602339 | ENSG00000163406 | 518089 | 6565 | NM_021082 | transport /// oligopeptide transport | transporter activity /// oligopeptide transporter activity /// symporter activity /// peptide:hydrogen symporter activity | integral to plasma membrane /// membrane /// integral to membrane | --- | ---
AJ132820 | a disintegrin and metalloproteinase domain 5 | ADAM5 | 7-3 | 0.022432948 | decreased | 3.215323073423932 | 35902_at | --- | --- | 369765 | 255926 | --- | --- | --- | --- | --- | ---
AJ003147 | matrix metalloproteinase-like 1 | MMPL1 | 2-9 | 0.022539898 | increased | 2.284516128263478 | 35910_f_at | --- | ENSG00000008516 | --- | 4328 | NM_004142 | proteolysis and peptidolysis | metalloendopeptidase activity | extracellular matrix ([NAME]) | --- | ---
U88047 | AT rich interactive domain 3A (BRIGHT- like) | ARID3A | 2-9 | 0.043701949 | increased | 2.458026782914469 | 35913_at | 603265 | ENSG00000116017 | 501296 | 1820 | NM_005224 | transcription /// regulation of transcription, DNA-dependent | DNA binding /// transcription factor activity | intracellular /// nucleus | --- | ---
M98447 | transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) | [NAME] | 9-3 | 0.031245864 | decreased | 1.207532643542574 | 35947_at | 190195 /// 242100 /// 242300 | ENSG00000092295 | 508950 | 7051 | NM_000359 | peptide cross-linking | protein-glutamine gamma-glutamyltransferase activity /// calcium ion binding /// acyltransferase activity /// transferase activity | membrane fraction /// membrane | --- | ---
AL034562 | prodynorphin | PDYN | 8-3 | 0.026787887 | decreased | 1.480297974274582 | 35954_at | 131340 | ENSG00000101327 | 22584 | 5173 | NM_024411 | neuropeptide signaling pathway /// synaptic transmission | opioid peptide activity | plasma membrane | --- | ---
U10485 | lymphoid-restricted membrane protein | LRMP | 7-3 | 0.029703948 | decreased | 1.386298446365602 | 35974_at | 602003 | ENSG00000118308 | 124922 | 4033 | NM_006152 | vesicle targeting /// vesicle fusion /// hemocyte development | --- | endoplasmic reticulum membrane /// integral to plasma membrane | --- | ---
AL050395 | [NAME] histone acetyltransferase 1 | MYST1 | 1-7 | 0.016775017 | increased | 1.54506575855392 | 35986_at | --- | ENSG00000103510 | 533803 | 84148 | NM_032188 | chromatin assembly or disassembly | chromatin binding /// transferase activity | chromatin /// nucleus | --- | ---
AL050395 | [NAME] histone acetyltransferase 1 | MYST1 | 1-8 | 0.043442246 | increased | 1.436057290298234 | 35987_g_at | --- | ENSG00000103510 | 533803 | 84148 | NM_032188 | chromatin assembly or disassembly | chromatin binding /// transferase activity | chromatin /// nucleus | --- | ---
Y18643 | methyltransferase like 1 | METTL1 | 10-3 | 0.03822035 | decreased | 1.672366760010874 | 36001_at | 604466 | ENSG00000037897 | 42957 | 4234 | NM_005371 /// NM_023032 /// NM_023033 | tRNA modification /// tRNA processing | tRNA (guanine-N7-)-methyltransferase activity /// S-adenosylmethionine-dependent methyltransferase activity /// transferase activity | --- | --- | ---
U28831 | KIAA1641 /// similar to KIAA1641 protein | KIAA1641 /// LOC440889 | 10-3 | 0.042817654 | decreased | 0.6561103944416389 | 36020_at | --- | ENSG00000174501 /// ENSG00000187998 | 516348 | 440889 /// 57730 | [NAME] /// XM_496576 | --- | --- | --- | --- | ---
AF091754 | exonuclease 1 | [NAME] | 9-1 | 0.024724098 | decreased | 1.65010228491424 | 36041_at | 606063 | ENSG00000174371 | 498248 | 9156 | NM_003686 /// NM_006027 /// NM_130398 | DNA repair /// mismatch repair /// DNA recombination | DNA binding /// DNA binding /// ribonuclease H activity /// exonuclease activity /// 5'-3' exonuclease activity | --- | --- | ---
L29217 | CDC-like kinase 3 | CLK3 | 1-7 | 0.007708401 | increased | 2.084088995491294 | 36115_at | 602990 | ENSG00000179335 | 511790 | 1198 | NM_001292 /// NM_003992 | protein amino acid phosphorylation | protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity | nucleus | mRNA_processing_Reactome | [NAME]
AF064093 | SPFH domain family, member 1 | SPFH1 | 10-3 | 0.018109753 | decreased | 1.186615214263804 | 36219_at | --- | ENSG00000095480 | 150087 | 10613 | NM_006459 | --- | catalytic activity | --- | --- | ---
AB009698 | solute carrier family 22 (organic anion transporter), member 6 | SLC22A6 | 8-3 | 0.011967146 | decreased | 1.400254156205445 | 36237_at | 607582 | ENSG00000197901 | 369252 | 9356 | NM_004790 /// NM_153276 /// NM_153277 /// NM_153278 /// NM_153279 | ion transport /// sodium ion transport /// organic anion transport /// alpha-ketoglutarate transport | ATP binding /// organic anion transporter activity /// ion transporter activity /// symporter activity | membrane fraction /// integral to plasma membrane /// integral to membrane | --- | ---
AF095687 | nasopharyngeal carcinoma associated gene protein-8 | [NAME] | 10-3 | 0.016299535 | decreased | 1.907601449146421 | 36259_at | --- | ENSG00000188901 | 534410 | 27099 | NM_014411 | --- | --- | --- | --- | ---
M23323 | CD3E antigen, epsilon polypeptide (TiT3 complex) | CD3E | 2-9 | 0.025075023 | increased | 1.510459165011079 | 36277_at | 186830 | ENSG00000198851 | 3003 | 916 | NM_000733 | protein complex assembly /// signal complex formation /// G-protein coupled receptor protein signaling pathway /// positive regulation of T-cell proliferation /// T-cell activation /// regulation of apoptosis | [NAME] receptor activity /// SH3 domain binding /// protein kinase binding /// receptor signaling complex scaffold activity /// T-cell receptor binding /// protein heterodimerization activity | integral to plasma membrane /// membrane /// T-cell receptor complex | --- | ---
AC005952 | insulin-like 3 ([NAME] cell) | INSL3 | 9-2 | 0.013437704 | decreased | 2.396560833253781 | 36301_at | 146738 /// 219050 | ENSG00000105639 | 37062 | 3640 | NM_005543 | cell-cell signaling /// spermatogenesis /// physiological process | insulin receptor binding /// hormone activity | extracellular region /// extracellular region /// soluble fraction | --- | ---
AB011180 | TBC1 domain family, member 12 | TBC1D12 | 10-3 | 0.040548428 | decreased | 2.129348539625525 | 36320_at | --- | ENSG00000108239 | 500598 | 23232 | XM_051081 | --- | GTPase activator activity | --- | --- | ---
[NAME] | cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase) | CCBL1 | 2-9 | 0.021541301 | increased | 2.357468975481532 | 36330_at | 600547 | ENSG00000171097 | 495250 | 883 | NM_004059 | amino acid derivative metabolism /// biosynthesis | kynurenine-oxoglutarate transaminase activity /// lyase activity /// 1-aminocyclopropane-1-carboxylate synthase activity /// glutamine-phenylpyruvate transaminase activity /// cysteine-S-conjugate beta-lyase activity | [NAME] | --- | ---
U34038 | coagulation factor II (thrombin) receptor-like 1 | F2RL1 | 10-3 | 0.035425972 | decreased | 2.031806455032692 | 36345_g_at | 600933 | ENSG00000164251 | 154299 | 2150 | NM_005242 | signal transduction /// G-protein coupled receptor protein signaling pathway /// positive regulation of cytosolic calcium ion concentration /// blood coagulation | rhodopsin-like receptor activity /// receptor activity /// receptor binding /// thrombin receptor activity | Golgi apparatus /// plasma membrane /// integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm
Z98744 | histone 1, H2bn | HIST1H2BN | 6-2 | 0.00626822 | decreased | 2.370907927524217 | 36347_f_at | 602801 | ENSG00000196501 | 534368 | 8341 | /// NM_003520 | nucleosome assembly /// nucleosome assembly /// nucleosome assembly /// chromosome organization and biogenesis (sensu [NAME]) | DNA binding /// DNA binding /// DNA binding | nucleosome /// nucleosome /// nucleosome /// nucleus /// chromosome | --- | ---
L34081 | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | BAAT | 10-3 | 0.042734906 | decreased | 1.443873079055224 | 36384_at | 602938 /// 607748 | ENSG00000136881 | 284712 | 570 | NM_001701 | glycine metabolism /// lipid metabolism /// digestion /// bile acid metabolism | acyltransferase activity /// palmitoyl-CoA hydrolase activity /// transferase activity | [NAME] | Bile acid biosynthesis /// Taurine and hypotaurine metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00120+2.3.1.65 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00430+2.3.1.65
AB011082 | solute carrier family 22 (organic cation transporter), member 14 | SLC22A14 | 2-9 | 0.013833161 | increased | 2.152325339435067 | 36408_at | 604048 | [NAME] | 165559 | 9389 | NM_004803 | transport | transporter activity /// organic cation transporter activity | membrane fraction /// integral to plasma membrane | --- | ---
AL079298 | methylcrotonoyl-Coenzyme A carboxylase 2 (beta) | MCCC2 | 1-9 | 0.030659091 | increased | 1.557093119844483 | 36432_at | 609014 | ENSG00000131844 | 167531 | 64087 | NM_022132 | leucine catabolism | methylcrotonoyl-CoA carboxylase activity /// ligase activity | mitochondrion | [NAME], leucine and isoleucine degradation | www.genome.ad.jp/dbget-bin/show_pathway?MAP00280+6.4.1.4
U93917 | glycine receptor, alpha 3 | GLRA3 | 9-1 | 0.014280783 | decreased | 1.453739154086333 | 36433_at | 600421 | ENSG00000145451 | 413099 | 8001 | NM_006529 | ion transport /// chloride transport /// synaptic transmission | GABA-A receptor activity /// ion channel activity /// extracellular ligand-gated ion channel activity /// glycine binding /// glycine-gated chloride channel activity /// neurotransmitter receptor activity | integral to membrane /// glycine-gated chloride channel complex /// postsynaptic membrane | --- | ---
U26742 | dystrobrevin, alpha | DTNA | 2-9 | 0.000297923 | increased | 1.914719855249853 | 36466_at | 601239 /// 604169 /// 606617 | ENSG00000134769 | 58919 | 1837 | NM_001390 /// NM_001391 /// NM_001392 /// NM_032975 /// NM_032978 /// NM_032979 /// NM_032980 /// NM_032981 | striated muscle contraction /// signal transduction /// neuromuscular synaptic transmission | calcium ion binding /// protein binding /// zinc ion binding | synapse | --- | ---
X98253 | ring finger protein 113A | RNF113A | 10-3 | 0.007501165 | decreased | 2.218477645647877 | 36565_at | --- | ENSG00000125352 | 458365 | 7737 | NM_006978 | development /// protein ubiquitination | nucleic acid binding /// ubiquitin-protein ligase activity /// zinc ion binding | ubiquitin ligase complex | Electron_Transport_Chain | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm
U09585 | interferon-related developmental regulator 2 | IFRD2 | 3-3 | 0.037371913 | decreased | 1.564121966747894 | 36613_at | 602725 | [NAME] | 315177 | 7866 | NM_006764 | cell proliferation /// cell differentiation | binding | --- | --- | ---
[NAME] | [NAME], light polypeptide 2, regulatory, cardiac, slow | MYL2 | 2-9 | 0.024202095 | increased | 2.406988251831245 | 36640_at | 160781 /// 608758 | ENSG00000111245 | 75535 | 4633 | NM_000432 | regulation of striated muscle contraction /// muscle development | motor activity /// calcium ion binding /// structural constituent of muscle | cytoskeleton /// [NAME] | Smooth_muscle_contraction /// Striated_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Striated_muscle_contraction/Hs_Striated_muscle_contraction.htm
N50520 | cytochrome c oxidase subunit VIIb | COX7B | 3-3 | 0.01473281 | decreased | 1.550050674741379 | 36687_at | 603792 | ENSG00000131174 | 522699 | 1349 | NM_001866 | electron transport | cytochrome-c oxidase activity /// oxidoreductase activity | mitochondrion /// mitochondrial electron transport chain /// integral to membrane /// inner membrane | Electron_Transport_Chain /// Oxidative phosphorylation | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00190+1.9.3.1
AF043472 | potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3 | KCNS3 | 2-9 | 0.013127451 | increased | 1.821103661527665 | 36694_at | 603888 | ENSG00000170745 | 414489 | 3790 | NM_002252 | cation transport /// potassium ion transport | delayed rectifier potassium channel activity /// protein binding /// potassium channel regulator activity | membrane fraction /// voltage-gated potassium channel complex /// membrane | --- | ---
AI290480 | olfactomedin-like 1 | OLFML1 | 3-3 | 0.036752549 | decreased | 2.256058575144412 | 36695_at | --- | ENSG00000183801 | 503500 | 283298 | NM_198474 | --- | --- | --- | --- | ---
D25235 | adrenergic, alpha-1A-, receptor | ADRA1A | 6-3 | 0.010398501 | decreased | 1.718992809073208 | 36715_at | 104221 | ENSG00000120907 | 52931 | 148 | NM_000680 /// NM_033302 /// NM_033303 /// NM_033304 | apoptosis /// smooth muscle contraction /// signal transduction /// G-protein coupled receptor protein signaling pathway /// protein kinase cascade /// cell-cell signaling /// negative regulation of cell proliferation | rhodopsin-like receptor activity /// receptor activity /// adrenoceptor activity /// [NAME] receptor activity /// [NAME] receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Monoamine_GPCRs /// Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Monoamine_GPCRs/Hs_Monoamine_GPCRs.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
D32202 | adrenergic, alpha-1A-, receptor | ADRA1A | 8-3 | 0.025419728 | decreased | 1.840412816937593 | 36716_at | 104221 | ENSG00000120907 | 52931 | 148 | NM_000680 /// NM_033302 /// NM_033303 /// NM_033304 | apoptosis /// smooth muscle contraction /// signal transduction /// G-protein coupled receptor protein signaling pathway /// protein kinase cascade /// cell-cell signaling /// negative regulation of cell proliferation | rhodopsin-like receptor activity /// receptor activity /// adrenoceptor activity /// [NAME] receptor activity /// [NAME] receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Monoamine_GPCRs /// Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Monoamine_GPCRs/Hs_Monoamine_GPCRs.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
U95626 | chemokine (C-C motif) receptor 5 | CCR5 | 10-3 | 0.011576523 | decreased | 1.535994862610598 | 36724_s_at | 601373 | ENSG00000188239 /// ENSG00000160791 | 546245 | 1234 | NM_000579 | G-protein coupled receptor protein signaling pathway | rhodopsin-like receptor activity /// receptor activity /// C-C chemokine receptor activity | integral to membrane | GPCRDB_Class_A_Rhodopsin-like /// Peptide_GPCRs /// GPCRDB_Other | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Other/Hs_GPCRDB_Other.htm
M94055 | sodium channel, voltage-gated, type II, alpha 2 | SCN2A2 | 10-3 | 0.013754384 | decreased | 1.280352013539877 | 36725_at | 601219 | ENSG00000136531 | 470470 | 6326 | NM_021007 | cation transport /// sodium ion transport | voltage-gated sodium channel activity /// cation channel activity | voltage-gated sodium channel complex /// membrane | --- | ---
M76446 | adrenergic, alpha-1D-, receptor | ADRA1D | 2-9 | 0.034725237 | increased | 1.908379017211237 | 36729_g_at | 104219 | ENSG00000171873 | 557 | 146 | NM_000678 | DNA metabolism /// signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein signaling, coupled to cAMP nucleotide second messenger /// cell-cell signaling /// development /// cell proliferation /// positive regulation of cell proliferation | rhodopsin-like receptor activity /// receptor activity /// adrenoceptor activity /// [NAME] receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Monoamine_GPCRs /// Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Monoamine_GPCRs/Hs_Monoamine_GPCRs.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
AF035308 | similar to hypothetical protein Y97E10AL.1 | DKFZp761P211 | 1-8 | 0.002187003 | increased | 1.63267947012454 | 36745_at | --- | --- | 116827 | 375057 | NM_001003665 | --- | --- | --- | --- | ---
AL079276 | zinc finger protein 339 | ZNF339 | 8-3 | 0.008368663 | decreased | 2.059486207973575 | 36761_at | --- | ENSG00000125850 | 546418 | 58495 | NM_021220 | transcription /// regulation of transcription, DNA-dependent | DNA binding /// zinc ion binding | nucleus | --- | ---
U79249 | hypothetical protein AY099107 | LOC152185 | 7-3 | 0.021687874 | decreased | 2.021038217807986 | 36793_at | --- | ENSG00000163611 | 477144 | 152185 | NM_144718 | --- | --- | --- | --- | ---
M26004 | complement component (3d/Epstein Barr virus) receptor 2 | CR2 | 4-10 | 0.036023454 | increased | 2.496623551691207 | 36874_at | 120650 | ENSG00000117322 | 445757 | 1380 | NM_001006658 /// NM_001877 | immune response /// complement activation, classical pathway | receptor activity /// complement receptor activity | plasma membrane /// integral to membrane | --- | ---
L28824 | [NAME] | SYK | 5-3 | 0.000206861 | decreased | 2.100022202978928 | 36885_at | 600085 | ENSG00000165025 | 371720 | 6850 | NM_003177 | protein complex assembly /// protein amino acid phosphorylation /// [NAME] cell adhesion /// integrin-mediated signaling pathway /// intracellular signaling cascade /// cell proliferation /// organogenesis /// neutrophil chemotaxis | protein-tyrosine kinase activity /// integrin binding /// ATP binding /// transferase activity | --- | --- | ---
M98045 | folylpolyglutamate synthase | FPGS | 6-2 | 0.012043645 | decreased | 2.425245144428798 | 36923_at | 136510 | ENSG00000136877 | 335084 | 2356 | NM_004957 | nucleobase, nucleoside, nucleotide and nucleic acid metabolism /// one-carbon compound metabolism /// biosynthesis /// folic acid and derivative biosynthesis | tetrahydrofolylpolyglutamate synthase activity /// ATP binding /// ligase activity | mitochondrion /// cytosol | Folate biosynthesis | www.genome.ad.jp/dbget-bin/show_pathway?MAP00790+6.3.2.17
AL050286 | LETM1 domain containing 1 | LETMD1 | 3-1 | 0.025426073 | decreased | 2.515627850299492 | 36961_at | --- | ENSG00000050426 | 370457 | 25875 | NM_015416 | --- | --- | --- | --- | ---
D42053 | membrane-bound transcription factor protease, site 1 | MBTPS1 | 6-2 | 0.000206705 | decreased | 2.493397239853314 | 36964_at | 603355 | [NAME] | 75890 | 8720 | NM_003791 /// NM_201268 | proteolysis and peptidolysis /// proteolysis and peptidolysis /// lipid metabolism /// steroid metabolism /// cholesterol metabolism | subtilase activity /// peptidase activity | endoplasmic reticulum lumen /// Golgi apparatus /// integral to membrane | --- | ---
M24486 | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I | P4HA1 | 4-7 | 0.017759356 | increased | 1.152218190614816 | 37037_at | 176710 | ENSG00000122884 | 500047 | 5033 | [NAME] | --- | procollagen-proline 4-dioxygenase activity /// binding /// oxidoreductase activity /// oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | endoplasmic reticulum | Arginine and proline metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00330+1.14.11.2
AB023161 | [NAME], axonemal, heavy polypeptide 7 | DNAH7 | 2-9 | 0.003062088 | increased | 2.19380581865917 | 37081_at | --- | ENSG00000118997 | 97403 | 56171 | NM_018897 | ciliary or flagellar motility | microtubule motor activity /// ATP binding /// ATPase activity | axonemal dynein complex | --- | ---
AF022795 | transforming growth factor, beta receptor associated protein 1 | TGFBRAP1 | 10-3 | 0.038542413 | decreased | 3.157899119084902 | 37113_at | 606237 | ENSG00000135966 | 446350 | 9392 | NM_004257 | transforming growth factor beta receptor signaling pathway | receptor activity | --- | --- | ---
D88154 | villin-like | VILL | 10-3 | 0.022004963 | decreased | 1.433393091888296 | 37123_at | --- | ENSG00000136059 | 103665 | 50853 | NM_015873 | cytoskeleton organization and biogenesis | [NAME] binding /// structural constituent of cytoskeleton | [NAME] | --- | ---
AI936758 | neuropeptide FF-amide peptide precursor | NPFF | 2-8 | 0.018750222 | increased | 1.627097302926698 | 37129_at | 604643 | ENSG00000139574 | 104555 | 8620 | NM_003717 | neuropeptide signaling pathway /// synaptic transmission | receptor binding /// neuropeptide hormone activity | soluble fraction | --- | ---
AB008390 | [NAME] (neuropsin/ovasin) | [NAME] | 5-3 | 0.015045628 | decreased | 3.057100516928876 | 37131_at | 605644 | ENSG00000129455 | 104570 | 11202 | NM_007196 /// NM_144505 /// NM_144506 /// NM_144507 | proteolysis and peptidolysis /// neurogenesis | chymotrypsin activity /// trypsin activity /// peptidase activity | --- | --- | ---
J04162 | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) | FCGR3A | 3-3 | 0.004662446 | decreased | 2.181079594865857 | 37200_at | 146740 /// 152700 | ENSG00000162747 | --- | 2214 | NM_000569 | immune response | receptor activity /// IgG binding | plasma membrane /// integral to membrane | --- | ---
U19251 | baculoviral IAP repeat-containing 1 | BIRC1 | 7-4 | 0.000618754 | decreased | 1.721533767723999 | 37277_at | 600355 | ENSG00000081770 | 519374 | 4671 | NM_004536 | apoptosis /// anti-apoptosis /// anti-apoptosis /// neurogenesis | nucleotide binding /// nucleoside-triphosphatase activity | intracellular | --- | ---
L25107 | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | PAFAH1B1 | 1-7 | 0.031084195 | increased | 2.501273318788344 | 37317_at | 601545 /// 607432 | ENSG00000007168 | 77318 | 5048 | NM_000430 | establishment of mitotic spindle orientation /// cytokinesis /// lipid metabolism /// cell motility /// microtubule-based process /// cell cycle /// mitosis /// signal transduction /// neurogenesis /// cell differentiation | [NAME] | astral microtubule /// kinetochore /// nuclear membrane /// cytoskeleton /// microtubule associated complex /// cell cortex | Wnt_signaling /// Glycerophospholipid metabolism | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00564+3.1.1.47
U24266 | aldehyde dehydrogenase 4 family, member [NAME] | ALDH4A1 | 1-6 | 0.02221604 | increased | 1.773480846430014 | 37330_at | 239510 /// 606811 | ENSG00000159423 | 77448 | 8659 | NM_003748 /// NM_170726 | proline biosynthesis /// proline catabolism /// metabolism | 1-pyrroline-5-carboxylate dehydrogenase activity /// aldehyde dehydrogenase (NAD) activity /// electron transporter activity /// oxidoreductase activity | mitochondrial matrix | Glutamate metabolism /// Arginine and proline metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00251+1.5.1.12 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00330+1.5.1.12
M60618 | nuclear antigen Sp100 | SP100 | 4-10 | 0.025214673 | increased | 2.247495598234209 | 37353_g_at | 604585 | ENSG00000067066 | 369056 | 6672 | NM_003113 | regulation of transcription, DNA-dependent | DNA binding | chromatin /// nucleus | --- | ---
U72511 | prohibitin 2 | PHB2 | 10-3 | 0.012020337 | decreased | 1.721865043087124 | 37364_at | --- | --- | 504620 | 11331 | NM_007273 | DNA metabolism /// negative regulation of transcription | receptor activity /// estrogen receptor binding | --- | --- | ---
M81780 | --- | --- | 1-7 | 0.00523368 | increased | 1.887765611445364 | 37371_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
U30246 | solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | SLC12A2 | 6-2 | 0.036748592 | decreased | 4.548011195173774 | 37423_at | 600840 | ENSG00000064651 | 162585 | 6558 | NM_001046 | ion transport /// potassium ion transport /// sodium ion transport /// chloride transport /// amino acid transport | transporter activity /// amino acid-polyamine transporter activity /// sodium:potassium:chloride symporter activity /// symporter activity | membrane fraction /// integral to plasma membrane /// membrane | --- | ---
AF077953 | protein inhibitor of activated STAT, 2 | PIAS2 | 8-3 | 0.037145587 | decreased | 1.824286966591945 | 37432_g_at | 603567 | ENSG00000078043 | 514846 | 9063 | NM_004671 /// NM_173206 | transcription /// regulation of transcription, DNA-dependent /// ubiquitin cycle /// development | DNA binding /// zinc ion binding | nucleus | --- | ---
U62801 | kallikrein 6 (neurosin, zyme) | KLK6 | 6-2 | 0.036425798 | decreased | 1.949305910815715 | 37554_at | 602652 | ENSG00000167755 | 79361 | 5653 | NM_001012964 /// NM_001012965 /// NM_001012966 /// NM_002774 | proteolysis and peptidolysis /// central nervous system development /// response to wounding /// protein autoprocessing /// collagen catabolism /// tissue regeneration /// hormone metabolism /// myelination /// amyloid precursor protein metabolism /// regulation of cell differentiation | chymotrypsin activity /// tissue kallikrein activity /// trypsin activity /// protein binding /// peptidase activity | extracellular region /// cytoplasm | --- | ---
AL050143 | sushi, nidogen and EGF-like domains 1 | SNED1 | 10-3 | 0.003313856 | decreased | 1.71385462214374 | 37560_at | --- | ENSG00000162804 | 471834 | 25992 | [NAME] | cell-matrix adhesion | calcium ion binding | --- | --- | ---
X85750 | monocyte to macrophage differentiation-associated | MMD | 10-3 | 0.034940169 | decreased | 1.208456157627063 | 37565_at | 604467 | ENSG00000108960 | 463483 | 23531 | NM_012329 | cytolysis | receptor activity | membrane fraction /// integral to plasma membrane /// integral to membrane | --- | ---
AJ005168 | ketohexokinase (fructokinase) | KHK | 3-1 | 0.025878596 | decreased | 1.620301006723368 | 37608_g_at | 229800 | ENSG00000138030 | 159525 | 3795 | NM_000221 /// NM_006488 | carbohydrate metabolism | ketohexokinase activity /// kinase activity /// transferase activity | --- | Fructose and mannose metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00051+2.7.1.3
M86737 | structure specific recognition protein 1 | SSRP1 | 5-4 | 0.005881333 | decreased | 2.282857247250121 | 37739_at | 604328 | ENSG00000149136 | 523680 | 6749 | NM_003146 | regulation of transcription, DNA-dependent | DNA binding | chromatin /// nucleus | --- | ---
Y08134 | sphingomyelin phosphodiesterase, acid-like 3B | SMPDL3B | 1-8 | 0.024800605 | increased | 1.889882015854963 | 37779_at | --- | ENSG00000130768 | 123659 | 27293 | NM_001009568 /// NM_014474 | carbohydrate metabolism | hydrolase activity /// hydrolase activity, acting on glycosyl bonds | --- | --- | ---
AB023138 | neurexin 2 | NRXN2 | 1-8 | 0.039505117 | increased | 3.255047786724163 | 37781_at | 600566 | ENSG00000110076 | 372938 | 9379 | [NAME] /// NM_138732 /// NM_138734 | cell adhesion | structural molecule activity /// protein binding | integral to membrane | --- | ---
AF070575 | --- | --- | 2-9 | 0.006435541 | increased | 2.621827553685612 | 37783_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
AF035281 | hypothetical protein LOC155060 | LOC155060 | 2-9 | 0.040457778 | increased | 1.790578579882739 | 37794_at | --- | --- | 490512 | 155060 | NM_001004302 | regulation of transcription, DNA-dependent | nucleic acid binding | nucleus | --- | ---
U41813 | homeo box A9 | HOXA9 | 10-3 | 0.015406417 | decreased | 1.375581038156835 | 37809_at | 142956 | ENSG00000078399 | 127428 | 3205 | NM_002142 /// NM_152739 | transcription /// regulation of transcription, DNA-dependent /// development | transcription factor activity /// transcriptional activator activity | nucleus /// nucleus | --- | ---
AF042792 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | CACNA2D2 | 9-1 | 0.024595934 | decreased | 3.147452363654735 | 37811_at | 607082 | ENSG00000007402 | 476273 | 9254 | NM_001005505 /// NM_006030 | ion transport /// calcium ion transport | voltage-gated ion channel activity /// calcium channel activity | membrane /// integral to membrane | --- | ---
AF041260 | breast carcinoma amplified sequence 1 | BCAS1 | 9-1 | 0.042923755 | decreased | 0.8798208914963785 | 37821_at | 602968 | ENSG00000064787 | 400556 | 8537 | NM_003657 | --- | --- | --- | --- | ---
AC002550 | Similar to TSG118.1 | --- | 9-3 | 0.034803599 | decreased | 1.823538101885924 | 37822_at | --- | --- | 546615 | 400506 | NM_001012991 | --- | --- | --- | --- | ---
AB028997 | ankyrin repeat domain 26 | ANKRD26 | 2-9 | 0.041069698 | increased | 2.561070314659001 | 37824_at | --- | ENSG00000107890 | 361041 | 22852 | NM_014915 | --- | --- | --- | --- | ---
AL109700 | CDNA FLJ37610 fis, clone BRCOC2011398 | --- | 1-8 | 0.029040083 | increased | 1.140867446925475 | 37839_at | --- | --- | 526470 | --- | --- | --- | --- | --- | --- | ---
AI857458 | urocortin | UCN | 8-3 | 0.030586621 | decreased | 1.258266123935104 | 37853_at | 600945 | ENSG00000163794 | 534363 | 7349 | NM_003353 | G-protein coupled receptor protein signaling pathway | neuropeptide hormone activity | extracellular region | --- | ---
AF072468 | [NAME] (mouse) | JRK | 2-9 | 0.036847851 | increased | 0.9540681170879778 | 37873_g_at | 603210 | --- | 546319 | 8629 | NM_003724 | --- | DNA binding | nucleus | --- | ---
AA846749 | apolipoprotein M | APOM | 6-2 | 0.000344319 | decreased | 1.75563816836662 | 37923_at | 606907 | ENSG00000111964 | 534468 | 55937 | NM_019101 | generation of precursor metabolites and energy /// membrane lipid metabolism /// lipid transport | lipid transporter activity | integral to plasma membrane | --- | ---
U00802 | drebrin 1 | DBN1 | 4-10 | 0.030344668 | increased | 2.17023807426304 | 37981_at | 126660 | ENSG00000113758 | 130316 | 1627 | NM_004395 /// NM_080881 | actin filament organization /// neurogenesis /// cell differentiation /// regulation of neuronal synaptic plasticity /// regulation of dendrite morphogenesis | [NAME] binding /// actin binding /// profilin binding | intracellular /// cytoplasm /// actin cytoskeleton /// dendrite /// actomyosin | --- | ---
M60459 | --- | --- | 2-9 | 0.002690498 | increased | 1.801323794006455 | 37986_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
AF071538 | SAM pointed domain containing ets transcription factor | SPDEF | 9-2 | 0.018232794 | decreased | 1.482559763504805 | 38009_at | 608144 | ENSG00000124664 | 485158 | 25803 | NM_012391 | regulation of transcription, DNA-dependent /// development | transcription factor activity /// protein binding | nucleus | --- | ---
AI683748 | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa | POLR2J | 9-2 | 0.023725039 | decreased | 2.230846631822444 | 38055_at | 604150 | ENSG00000005075 | 533383 | 5439 | NM_006234 | transcription /// transcription from RNA polymerase II promoter | DNA binding /// DNA-directed RNA polymerase activity /// transferase activity /// protein dimerization activity | nucleus /// DNA-directed RNA polymerase II, core complex | RNA_transcription_Reactome /// Purine metabolism /// Pyrimidine metabolism /// RNA polymerase | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_RNA_transcription_Reactome/Hs_RNA_transcription_Reactome.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+2.7.7.6 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00240+2.7.7.6 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03020+2.7.7.6
M80563 | S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) | S100A4 | 5-4 | 0.04403279 | decreased | 1.852285343798926 | 38088_r_at | 114210 | ENSG00000196154 | 81256 | 6275 | NM_002961 /// NM_019554 | --- | calcium ion binding | --- | --- | ---
AF038176 | Hypothetical protein FLJ11193 | FLJ11193 | 10-3 | 0.031495652 | decreased | 1.595185721800269 | 38141_at | --- | ENSG00000082213 | 519246 | 55322 | NM_018356 | --- | --- | --- | --- | ---
AF002672 | loss of heterozygosity, 11, chromosomal region 2, gene A | LOH11CR2A | 8-3 | 0.041091207 | decreased | 1.199404800289794 | 38151_at | 602929 | ENSG00000110002 | 152944 | 4013 | NM_014622 /// NM_198315 | --- | catalytic activity | --- | --- | ---
X99688 | pleckstrin and Sec7 domain containing | PSD | 1-7 | 0.026194685 | increased | 2.004475557546626 | 38174_at | 602327 | ENSG00000059915 | 154658 | 5662 | NM_002779 | --- | catalytic activity | --- | --- | ---
U45255 | paired box gene 2 | [NAME] | 3-2 | 0.010546598 | decreased | 2.87054966194281 | 38186_g_at | 120330 /// 167409 | ENSG00000075891 | 155644 | 5076 | NM_000278 /// NM_003987 /// NM_003988 /// NM_003989 /// NM_003990 | GTP biosynthesis /// UTP biosynthesis /// CTP biosynthesis /// transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// development /// axonogenesis /// visual perception /// cell differentiation | DNA binding /// DNA binding /// nucleoside-diphosphate kinase activity /// ATP binding | nucleus | --- | ---
U11690 | FYVE, [NAME] and PH domain containing 1 (faciogenital dysplasia) | FGD1 | 9-1 | 0.003284597 | decreased | 1.451876417231001 | 38200_at | 305400 | ENSG00000102302 | 522663 | 2245 | NM_004463 | cytoskeleton organization and biogenesis /// signal transduction /// development /// regulation of cell shape /// organogenesis /// actin cytoskeleton organization and biogenesis /// regulation of Cdc42 GTPase activity /// filopodium formation | guanyl-nucleotide exchange factor activity /// protein binding /// zinc ion binding /// small GTPase binding | ruffle /// Golgi apparatus /// cytoskeleton /// lamellipodium | --- | ---
M97347 | glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase) | GCNT1 | 10-3 | 0.024372906 | decreased | 0.8438786509169914 | 38218_at | 600391 | ENSG00000187210 | 521568 | 2650 | NM_001490 | O-linked glycosylation | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity /// acetylglucosaminyltransferase activity /// transferase activity, transferring glycosyl groups | Golgi apparatus /// membrane /// integral to membrane | O-Glycan biosynthesis | www.genome.ad.jp/dbget-bin/show_pathway?MAP00512+2.4.1.102
AF075680 | Ankyrin repeat domain 17 | ANKRD17 | 9-3 | 0.024634593 | decreased | 1.853294389867417 | 38244_at | --- | ENSG00000132466 | 518804 | 26057 | NM_032217 /// NM_198889 | mismatch repair /// response to mercury ion | nucleic acid binding /// damaged DNA binding /// ATP binding /// lyase activity | --- | --- | ---
Z97632 | vestigial like 1 (Drosophila) | VGLL1 | 10-3 | 0.001138398 | decreased | 1.569556783706615 | 38249_at | --- | ENSG00000102243 | 496843 | 51442 | NM_016267 | regulation of transcription, DNA-dependent | transcription coactivator activity /// transcription regulator activity | nucleus | --- | ---
U09584 | placental protein 6 | PL6 | 4-7 | 0.001615955 | increased | 1.615194220503285 | 38274_at | 607069 | ENSG00000126062 | 91566 | 11070 | NM_007024 | signal transduction | guanyl-nucleotide exchange factor activity | integral to membrane | --- | ---
X98654 | phosphatidylinositol transfer protein, membrane-associated 1 | PITPNM1 | 1-8 | 0.027710244 | increased | 1.537549001681393 | 38297_at | 608794 | ENSG00000110697 | 372295 | 9600 | NM_004910 | lipid metabolism /// transport /// brain development /// phototransduction | phosphatidylinositol transporter activity /// metal ion binding | intracellular /// membrane fraction | --- | ---
Y12336 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) | RASGRP2 | 5-4 | 0.03635888 | decreased | 2.127004449798199 | 38359_at | 605577 | ENSG00000068831 | 99491 | 10235 | NM_005825 /// NM_153819 | regulation of cell growth /// small GTPase mediated signal transduction /// [NAME] protein signal transduction | guanyl-nucleotide exchange factor activity /// [NAME] guanyl-nucleotide exchange factor activity /// calcium ion binding /// calcium ion binding /// kinase activity /// diacylglycerol binding | cytosol /// plasma membrane | --- | ---
U90916 | chromosome 11 open reading frame 32 | C11orf32 | 2-5 | 0.043876679 | increased | 1.767299715428487 | 38411_at | --- | --- | --- | 442871 | --- | --- | --- | --- | --- | ---
M63488 | replication protein A1, 70kDa | RPA1 | 3-3 | 0.020179054 | decreased | 3.065451040363092 | 38481_at | 179835 | ENSG00000132383 | 461925 | 6117 | NM_002945 | DNA-dependent DNA replication /// DNA repair /// DNA recombination | single-stranded DNA binding | nucleus /// DNA replication factor A complex | DNA_replication_Reactome /// G1_to_S_cell_cycle_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_DNA_replication_Reactome/Hs_DNA_replication_Reactome.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G1_to_S_cell_cycle_Reactome/Hs_G1_to_S_cell_cycle_Reactome.htm
AA714670 | Kynureninase (L-kynurenine hydrolase) | [NAME] | 7-4 | 0.0091483 | decreased | 2.185283092025006 | 38493_at | 236800 | ENSG00000115919 | 470126 | 8942 | NM_003937 | tryptophan catabolism /// NAD biosynthesis | peptidase activity /// pyridoxal phosphate binding /// kynureninase activity | cytoplasm | Tryptophan metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+3.7.1.3
AL049435 | CDNA FLJ13601 fis, clone PLACE1010069 | --- | 8-3 | 0.007530929 | decreased | 1.586367451458609 | 38510_at | --- | --- | 407903 | --- | --- | --- | --- | --- | --- | ---
M13981 | inhibin, alpha | INHA | 5-4 | 0.034509572 | decreased | 2.213599530026811 | 38544_at | 147380 | ENSG00000123999 | 407506 | 3623 | NM_002191 | skeletal development /// ovarian follicle development /// induction of apoptosis /// cell cycle arrest /// cell surface receptor linked signal transduction /// cell-cell signaling /// neurogenesis /// response to external stimulus /// cell differentiation /// erythrocyte differentiation /// negative regulation of phosphorylation /// hemoglobin biosynthesis /// negative regulation of interferon-gamma biosynthesis /// negative regulation of B-cell differentiation /// negative regulation of macrophage differentiation /// negative regulation of cell cycle /// positive regulation of follicle-stimulating hormone secretion /// negative regulation of follicle-stimulating hormone secretion | cytokine activity /// hormone activity /// protein binding /// growth factor activity /// activin inhibitor activity | extracellular region | Ovarian_Infertility_Genes | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Ovarian_Infertility_Genes/Hs_Ovarian_Infertility_Genes.htm
U02683 | nuclear respiratory factor 1 | NRF1 | 8-2 | 0.01438451 | decreased | 1.962974375625874 | 38569_at | 600879 | ENSG00000106459 | 298069 | 4899 | NM_005011 | generation of precursor metabolites and energy /// transcription /// regulation of transcription, DNA-dependent /// regulation of transcription from RNA polymerase II promoter | transcription factor activity | nucleus /// nucleus | --- | ---
AC005622 | immunity-related GTPase family, cinema 1 | IRGC1 | 10-3 | 0.02634178 | decreased | 0.8579729859945419 | 38579_at | --- | ENSG00000124449 | 515444 | 56269 | NM_019612 | --- | --- | --- | --- | ---
AI828210 | KIAA0284 | KIAA0284 | 10-3 | 0.038917127 | decreased | 2.318827134360407 | 38593_r_at | --- | ENSG00000099814 | 533721 | 283638 | NM_015005 | --- | --- | --- | --- | ---
X14487 | [NAME] (epidermolytic hyperkeratosis; keratosis palmaris et plantaris) | KRT10 | 7-4 | 0.007452094 | decreased | 2.041865545726477 | 38610_s_at | 113800 /// 148080 /// 600648 /// 607602 | ENSG00000186395 | 99936 | 3858 | NM_000421 | epidermis development | structural molecule activity /// structural molecule activity /// structural constituent of epidermis | intermediate filament /// intermediate filament /// intermediate filament | --- | ---
M95585 | Hepatic leukemia factor | HLF | 1-8 | 0.024590763 | increased | 1.446485754229559 | 38627_at | 142385 | ENSG00000108924 | 196952 | 3131 | NM_002126 | transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// development /// rhythmic process | double-stranded DNA binding | nucleus | --- | ---
AF040963 | MAX dimerization protein 4 | MXD4 | 6-2 | 0.03349587 | decreased | 1.998392007779382 | 38639_at | --- | ENSG00000123933 | 102402 | 10608 | NM_006454 | negative regulation of transcription from RNA polymerase II promoter /// transcription /// regulation of transcription, DNA-dependent /// negative regulation of cell proliferation | DNA binding /// transcription corepressor activity /// protein binding | nucleus | --- | ---
AI582831 | zinc finger protein 593 | ZNF593 | 3-3 | 2.48e-05 | decreased | 2.20213147685068 | 38640_at | --- | ENSG00000142684 | 477273 | 51042 | NM_015871 | negative regulation of transcription from RNA polymerase II promoter /// transcription /// regulation of transcription, DNA-dependent | DNA binding /// transcription corepressor activity /// zinc ion binding | nucleus | --- | ---
AI033692 | barrier to autointegration factor 1 | BANF1 | 10-3 | 0.031292741 | decreased | 2.401183744276167 | 38663_at | 603811 | ENSG00000175334 | 433759 | 8815 | NM_003860 | response to virus | DNA binding | nucleus /// chromosome | --- | ---
AL050101 | component of oligomeric golgi complex 4 | [NAME] | 5-3 | 0.01609387 | decreased | 1.886936092672774 | 38718_at | 606976 | ENSG00000103051 | 208680 | 25839 | NM_015386 /// NM_145818 | protein transport | --- | Golgi apparatus /// membrane | --- | ---
X79067 | zinc finger protein 36, C3H type-like 1 | ZFP36L1 | 1-6 | 0.014728061 | increased | 2.439977284098523 | 38740_at | 601064 | ENSG00000185650 | 85155 | 677 | NM_004926 | --- | transcription factor activity | nucleus | --- | ---
AF023476 | A disintegrin and metalloproteinase domain 12 (meltrin alpha) | ADAM12 | 8-3 | 0.021619081 | decreased | 1.68136285181021 | 38770_at | 602714 | ENSG00000148848 | 386283 | 8038 | NM_003474 /// NM_021641 | proteolysis and peptidolysis /// cell adhesion /// myoblast fusion | metalloendopeptidase activity /// protein binding /// zinc ion binding | plasma membrane /// integral to membrane | --- | ---
X89750 | TGFB-induced factor (TALE family homeobox) | TGIF | 4-10 | 0.031552362 | increased | 2.050402734551244 | 38805_at | 142946 /// 602630 | ENSG00000177426 | 373550 | 7050 | NM_003244 /// NM_170695 /// NM_173207 /// NM_173208 /// NM_173209 /// NM_173210 /// NM_173211 /// NM_174886 | negative regulation of transcription from RNA polymerase II promoter /// transcription /// regulation of transcription, DNA-dependent /// development | transcription factor activity /// transcription factor activity /// transcription corepressor activity | nucleus /// nucleus | TGF_Beta_Signaling_Pathway | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_TGF_Beta_Signaling_Pathway/Hs_TGF_Beta_Signaling_Pathway.htm
M58460 | exosome component 9 | EXOSC9 | 10-3 | 0.011996363 | decreased | 1.991426355596182 | 38838_at | 606180 | ENSG00000123737 | 91728 | 5393 | NM_005033 | rRNA processing /// rRNA processing /// immune response | 3'-5'-exoribonuclease activity /// 3'-5'-exoribonuclease activity /// RNA binding /// [NAME] binding /// exonuclease activity /// hydrolase activity | nuclear exosome (RNase complex) /// exosome (RNase complex) /// nucleus /// nucleolus | --- | ---
W26851 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein | NFATC2IP | 10-3 | 0.033004885 | decreased | 1.875032485843754 | 38864_at | --- | ENSG00000176953 | 513470 | 84901 | NM_032815 | protein modification | --- | --- | --- | ---
W28996 | retinal degeneration, slow | RDS | 7-2 | 0.018417979 | decreased | 1.838518363947403 | 38874_s_at | 136880 /// 169150 /// 179605 /// 608133 /// 608161 | ENSG00000112619 | 532150 | 5961 | NM_000322 | cell adhesion /// sensory perception /// visual perception | protein binding | integral to membrane | --- | ---
AJ000730 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 | SLC7A4 | 2-9 | 0.001104874 | increased | 1.601657357446424 | 38897_at | 603752 | ENSG00000099960 | 197116 | 6545 | NM_004173 | amino acid metabolism /// transport /// amino acid transport | catalytic activity /// basic amino acid transporter activity | membrane /// integral to membrane | --- | ---
M61877 | spectrin, alpha, erythrocytic 1 (elliptocytosis 2) | SPTA1 | 2-9 | 0.020082657 | increased | 0.7976215752754678 | 38906_at | 182860 | ENSG00000163554 | 119825 | 6708 | NM_003126 | cellular morphogenesis /// actin filament organization | structural constituent of cytoskeleton /// calcium ion binding /// actin filament binding | membrane fraction /// cytoskeleton /// spectrin /// membrane | --- | ---
AJ011896 | TNFAIP3 interacting protein 1 | TNIP1 | 10-3 | 0.036406396 | decreased | 1.773334131603955 | 38970_s_at | 607714 | ENSG00000145901 | 355141 | 10318 | NM_006058 | defense response /// glycoprotein biosynthesis /// pathogenesis /// negative regulation of viral genome replication | protein binding | nucleus | --- | ---
AI223047 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa | NDUFA6 | 8-3 | 0.022257268 | decreased | 1.543379143905293 | 38983_at | 602138 | ENSG00000184983 | 274416 | 4700 | NM_002490 | electron transport | NADH dehydrogenase activity /// NADH dehydrogenase (ubiquinone) activity | membrane fraction /// mitochondrion /// mitochondrial inner membrane | Electron_Transport_Chain | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm
[NAME] | Fc fragment of IgG binding protein | FCGBP | 3-1 | 0.024267359 | decreased | 2.917529457205291 | 39014_at | --- | ENSG00000090920 | 111732 | 8857 | NM_003890 | cell adhesion /// binding of sperm to zona pellucida | --- | membrane | --- | ---
AA631972 | interleukin 32 | IL32 | 5-4 | 0.037622535 | decreased | 2.28141491223479 | 39119_s_at | 606001 | ENSG00000008517 | 943 | 9235 | NM_001012631 /// NM_001012632 /// NM_001012633 /// NM_001012634 /// NM_001012635 /// NM_001012636 /// NM_001012718 /// NM_004221 | immune response /// cell adhesion | cytokine activity | extracellular space | --- | ---
U31110 | transient receptor potential cation channel, subfamily C, member 1 | TRPC1 | 1-7 | 0.033279361 | increased | 2.502282004519134 | 39124_r_at | 602343 | ENSG00000144935 | 250687 | 7220 | NM_003304 | cation transport /// calcium ion transport | store-operated calcium channel activity | plasma membrane /// integral to plasma membrane | --- | ---
AL031290 | [NAME] | PAPPA2 | 7-3 | 0.02429091 | decreased | 2.168618809440838 | 39151_at | --- | ENSG00000116183 | 187284 | 60676 | NM_020318 /// NM_021936 | regulation of cell growth /// regulation of cell growth /// proteolysis and peptidolysis /// proteolysis and peptidolysis /// cell differentiation | metallopeptidase activity /// metallopeptidase activity /// zinc ion binding /// zinc ion binding | intracellular /// intracellular /// membrane | --- | ---
X99656 | SH3-domain GRB2-like 1 | SH3GL1 | 10-3 | 0.02460265 | decreased | 1.696102087238995 | 39159_at | 601626 /// 601768 | ENSG00000141985 | 97616 | 6455 | NM_003025 | --- | protein binding | cytoplasm | --- | ---
X89416 | protein phosphatase 5, catalytic subunit | [NAME] | 10-3 | 0.019664748 | decreased | 1.459312547856138 | 392_g_at | 600658 | ENSG00000011485 | 431861 | 5536 | NM_006247 | transcription /// protein amino acid dephosphorylation /// mitosis /// positive regulation of I-kappaB kinase/NF-kappaB cascade | protein serine/threonine phosphatase activity /// signal transducer activity /// binding /// hydrolase activity /// manganese ion binding | nucleus /// cytoplasm | --- | ---
AF091080 | hypothetical protein FLJ10374 | FLJ10374 | 9-1 | 0.040532566 | decreased | 1.296039381377395 | 39211_at | --- | ENSG00000105248 | 21811 | 55702 | NM_018074 | --- | --- | --- | --- | ---
AJ000008 | phosphoinositide-3-kinase, class 2, gamma polypeptide | PIK3C2G | 10-3 | 0.043349849 | decreased | 1.051786685698923 | 39222_at | 609001 | ENSG00000139144 | 22500 | 5288 | NM_004570 | intracellular signaling cascade | phosphatidylinositol 3-kinase activity /// transferase activity /// phosphatidylinositol-4-phosphate 3-kinase activity | phosphoinositide 3-kinase complex /// membrane | Inositol phosphate metabolism /// Phosphatidylinositol signaling system | www.genome.ad.jp/dbget-bin/show_pathway?MAP00562+2.7.1.137 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP04070+2.7.1.137
T83979 | serologically defined colon cancer antigen 1 | SDCCAG1 | 3-3 | 0.033119885 | decreased | 1.358684476519653 | 39228_at | 608378 | ENSG00000165525 | 388584 | 9147 | NM_004713 | --- | --- | nucleus | --- | ---
AB015629 | C-type lectin domain family 4, member M | CLEC4M | 5-3 | 0.00154112 | decreased | 1.50989525087652 | 39270_at | 605872 | ENSG00000104938 | 421437 | 10332 | NM_014257 /// NM_214675 /// NM_214676 /// NM_214677 /// NM_214678 /// NM_214679 | endocytosis /// [NAME] cell adhesion /// intracellular signaling cascade /// pathogenesis /// detection of pest, pathogen or parasite /// cell-cell recognition /// virus-host interaction /// virion attachment /// viral genome replication /// antigen presentation /// antigen processing /// intracellular virion transport /// enhancement of virulence /// peptide antigen transport | receptor activity /// sugar binding /// sugar binding /// mannose binding /// ICAM-3 receptor activity /// exogenous peptide antigen binding /// virion binding | integral to plasma membrane /// membrane | --- | ---
Y15062 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3 | B3GALT3 | 2-9 | 0.005427528 | increased | 1.930130985079384 | 39293_at | 111400 /// 603094 | ENSG00000169255 | 418062 | 8706 | NM_003781 /// NM_033167 /// NM_033168 /// NM_033169 | protein amino acid glycosylation | magnesium ion binding /// galactosyltransferase activity /// UDP-galactose beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity /// transferase activity, transferring glycosyl groups /// galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity | Golgi apparatus /// membrane /// integral to membrane | --- | ---
AF052514 | protease, serine, 16 (thymus) | PRSS16 | 4-9 | 0.015651002 | increased | 2.056771322572382 | 39306_at | 607169 | ENSG00000112812 | 274407 | 10279 | NM_005865 | proteolysis and peptidolysis /// protein catabolism | serine-type endopeptidase activity /// serine-type peptidase activity | --- | --- | ---
U13697 | caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase) | [NAME] | 10-3 | 0.028734354 | decreased | 1.599701210318123 | 39320_at | 147678 | ENSG00000137752 | 2490 | 834 | NM_001223 /// NM_033292 /// NM_033293 /// NM_033294 /// NM_033295 | proteolysis and peptidolysis /// signal transduction /// regulation of apoptosis /// positive regulation of I-kappaB kinase/NF-kappaB cascade | signal transducer activity /// protein binding /// cysteine-type peptidase activity /// caspase activator activity /// caspase activity | intracellular | Apoptosis /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
Z71460 | ATPase, H+ transporting, lysosomal V0 subunit a isoform 1 | ATP6V0A1 | 4-7 | 0.009473011 | increased | 1.926798120015726 | 39326_at | 192130 | ENSG00000033627 | 463074 | 535 | NM_005177 | ion transport /// proton transport | hydrogen ion transporter activity | membrane /// integral to membrane | Oxidative phosphorylation /// ATP synthesis /// Photosynthesis /// [NAME] assembly /// Type III secretion system | www.genome.ad.jp/dbget-bin/show_pathway?MAP00190+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00193+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00195+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP02040+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03070+3.6.3.14
S62138 | DNA-damage-inducible transcript 3 | DDIT3 | 6-3 | 0.038799688 | decreased | 2.229956075401248 | 39420_at | 126337 | ENSG00000175197 | 505777 | 1649 | NM_004083 | transcription /// regulation of transcription, DNA-dependent /// response to DNA damage stimulus /// cell cycle arrest | transcription factor activity /// transcription corepressor activity | nucleus | mRNA_processing_Reactome | [NAME]
AB023147 | chromosome 22 open reading frame 9 | C22orf9 | 6-2 | 0.041249232 | decreased | 2.116552295508874 | 39433_at | --- | ENSG00000100364 | 369682 | 23313 | NM_001009880 /// NM_015264 | --- | --- | --- | --- | ---
AB014592 | KIAA0692 protein | KIAA0692 | 8-3 | 0.041363365 | decreased | 1.55085845834087 | 39519_at | --- | --- | 524874 | 23141 | --- | --- | --- | nuclear membrane | --- | ---
D49817 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | PFKFB3 | 2-9 | 0.004593884 | increased | 1.403287081904564 | 39522_at | 605319 | ENSG00000170525 | 195471 | 5209 | NM_004566 | fructose 2,6-bisphosphate metabolism /// fructose 2,6-bisphosphate metabolism /// metabolism | catalytic activity /// 6-phosphofructo-2-kinase activity /// fructose-2,6-bisphosphate 2-phosphatase activity /// fructose-2,6-bisphosphate 2-phosphatase activity /// ATP binding /// kinase activity /// transferase activity /// hydrolase activity | --- | --- | ---
AB006190 | aquaporin 7 | AQP7 | 1-7 | 0.032559845 | increased | 2.874460178461288 | 39568_g_at | 602974 | ENSG00000165269 | 455323 | 364 | NM_001170 | generation of precursor metabolites and energy /// transport /// water transport /// excretion /// glycerol transport | transporter activity /// water channel activity /// glycerol channel activity | integral to plasma membrane /// membrane | --- | ---
AF047348 | amyloid beta (A4) precursor protein-binding, family A, member 2 (X11-like) | APBA2 | 10-3 | 0.006684994 | decreased | 1.849858091224285 | 39590_at | 602712 | ENSG00000034053 | 525718 | 321 | NM_005503 | neurogenesis /// protein transport | protein binding | --- | --- | ---
D63998 | mannosidase, alpha, class 2A, member 1 | MAN2A1 | 6-2 | 0.017941749 | decreased | 2.44523288107219 | 39663_at | 154582 | ENSG00000112893 | 432822 | 4124 | NM_002372 | carbohydrate metabolism /// mannose metabolism /// glycoprotein biosynthesis | alpha-mannosidase activity /// mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity /// hydrolase activity, acting on glycosyl bonds | membrane fraction /// Golgi apparatus /// integral to membrane | --- | ---
U52427 | polymerase (RNA) II (DNA directed) polypeptide G | POLR2G | 3-1 | 0.005695643 | decreased | 1.884576876084084 | 39747_at | 602013 | ENSG00000168002 | 14839 | 5436 | NM_002696 | transcription | RNA binding /// DNA-directed RNA polymerase activity /// transferase activity | nucleus | RNA_transcription_Reactome /// Purine metabolism /// Pyrimidine metabolism /// RNA polymerase | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_RNA_transcription_Reactome/Hs_RNA_transcription_Reactome.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+2.7.7.6 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00240+2.7.7.6 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03020+2.7.7.6
AB002318 | Talin 2 | TLN2 | 7-4 | 0.021224076 | decreased | 1.793921363315129 | 39765_at | 607349 | --- | 511686 | 83660 | NM_015059 | cell adhesion | [NAME] binding /// structural molecule activity /// protein binding | [NAME] /// synapse | --- | ---
U26032 | Eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | EIF2S1 | 10-3 | 0.029592517 | decreased | 1.716522223250307 | 39784_at | 603907 | ENSG00000134001 | 151777 | 1965 | NM_004094 | regulation of translation | RNA binding /// translation initiation factor activity | polysome /// eukaryotic translation initiation factor 2 complex | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
AC005253 | hypothetical protein MGC2749 | MGC2749 | 3-3 | 0.038631885 | decreased | 1.613356304561311 | 39810_at | --- | ENSG00000105700 | 369785 | 79036 | NM_024069 | two-component signal transduction system (phosphorelay) | two-component sensor molecule activity | --- | --- | ---
[NAME] | mitochondrial ribosomal protein L12 | MRPL12 | 3-3 | 0.007942653 | decreased | 2.924558555952835 | 39812_at | 602375 | ENSG00000183093 | 109059 | 6182 | NM_002949 | protein biosynthesis /// protein biosynthesis | RNA binding /// structural constituent of ribosome /// structural constituent of ribosome | intracellular /// mitochondrion /// mitochondrial large ribosomal subunit /// ribosome | --- | ---
W94101 | Chromosome 6 open reading frame 108 | C6orf108 | 6-2 | 0.023034535 | decreased | 2.305349278082328 | 39818_at | --- | ENSG00000112667 | 109752 | 10591 | NM_006443 /// NM_199184 | cell proliferation | --- | nucleus | --- | ---
AF044309 | syntaxin 11 | STX11 | 2-9 | 0.036130011 | increased | 2.002888146653563 | 39857_at | 605014 | ENSG00000135604 | 118958 | 8676 | NM_003764 | intracellular protein transport /// membrane fusion | SNAP receptor activity /// protein transporter activity | Golgi apparatus /// membrane | --- | ---
W87858 | Kinesin heavy chain member 2 | KIF2 | 1-7 | 0.001247756 | increased | 2.070631919983169 | 39885_at | 602591 | ENSG00000068796 | 552575 | 3796 | NM_004520 | microtubule-based movement | microtubule motor activity /// ATP binding | cytoskeleton /// microtubule associated complex | --- | ---
AL109699 | Hypothetical protein DKFZp547K1113 | DKFZp547K1113 | 10-3 | 0.018932692 | decreased | 2.08487813434624 | 39890_at | --- | ENSG00000140548 | 459311 | 374655 | NM_198526 | --- | nucleic acid binding /// zinc ion binding | nucleus | --- | ---
AJ006352 | ephrin-A4 | EFNA4 | 5-3 | 0.032272169 | decreased | 2.650184337290479 | 39947_at | 601380 | ENSG00000143620 | 449913 | 1945 | NM_005227 /// NM_182689 /// NM_182690 | cell-cell signaling | transmembrane-ephrin receptor activity | integral to plasma membrane /// membrane | --- | ---
AL050100 | hepatocellularcarcinoma-associated antigen HCA557a | [NAME] | 1-9 | 0.016943468 | increased | 1.512749732822298 | 39986_at | --- | ENSG00000123427 | 528351 | 25895 | NM_015433 /// NM_206914 | --- | --- | --- | --- | ---
[NAME] | Ras-related GTP binding B | RRAGB | 4-9 | 0.030246946 | increased | 2.126714429152981 | 39989_at | --- | ENSG00000083750 | 50282 | 10325 | NM_006064 /// NM_016656 | signal transduction | GTP binding | nucleus /// cytoplasm | --- | ---
D11466 | phosphatidylinositol glycan, class A (paroxysmal nocturnal hemoglobinuria) | PIGA | 4-7 | 0.027617348 | increased | 2.511585931571224 | 39993_at | 311770 | ENSG00000165195 | 137154 | 5277 | NM_002641 /// NM_020472 /// NM_020473 | biosynthesis | transferase activity, transferring glycosyl groups /// phosphatidylinositol N-acetylglucosaminyltransferase activity | endoplasmic reticulum membrane /// integral to membrane | --- | ---
U60519 | caspase 10, apoptosis-related cysteine protease | CASP10 | 5-3 | 0.009767197 | decreased | 1.752292232278802 | 39999_at | 137215 /// 601762 /// 603909 /// 605027 | ENSG00000003400 | 5353 | 843 | NM_001230 /// NM_032974 /// NM_032976 /// NM_032977 | proteolysis and peptidolysis /// induction of apoptosis /// regulation of apoptosis | protein binding /// cysteine-type peptidase activity /// caspase activity /// caspase activity | --- | Apoptosis /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
M60830 | ecotropic viral integration site 2B | EVI2B | 10-3 | 0.01341505 | decreased | 1.54679193184479 | 40019_at | 158381 | ENSG00000185862 | 5509 | 2124 | NM_006495 | --- | --- | integral to plasma membrane | --- | ---
X58851 | [NAME], light polypeptide 4, alkali; atrial, embryonic | MYL4 | 8-2 | 0.032607265 | decreased | 2.265004540952234 | 40062_s_at | 160770 | ENSG00000198336 | 463300 | 4635 | NM_001002841 /// NM_002476 | striated muscle contraction /// muscle development | motor activity /// phosphoprotein phosphatase activity /// calcium ion binding /// structural constituent of muscle /// structural constituent of muscle | [NAME] /// [NAME] /// [NAME] | Smooth_muscle_contraction /// Striated_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Striated_muscle_contraction/Hs_Striated_muscle_contraction.htm
AF000987 | eukaryotic translation initiation factor 1A, Y-linked | EIF1AY | 7-3 | 0.027215781 | decreased | 2.820779606879017 | 40097_at | 400014 | ENSG00000198692 | 461178 | 9086 | NM_004681 | protein biosynthesis /// translational initiation | RNA binding /// translation initiation factor activity | --- | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
D89937 | --- | --- | 8-3 | 0.039638305 | decreased | 2.04614990423161 | 40131_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
AI985019 | --- | --- | 7-4 | 0.014165698 | decreased | 1.259505056600579 | 40135_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
AI660225 | Coactivator-associated arginine methyltransferase 1 | CARM1 | 6-2 | 0.028879999 | decreased | 2.264807044561169 | 40183_at | 603934 | ENSG00000142453 | 371416 | 10498 | NM_199141 | regulation of transcription, DNA-dependent /// chromatin modification /// histone methylation | transcription coactivator activity /// protein binding /// protein methyltransferase activity /// S-adenosylmethionine-dependent methyltransferase activity /// transferase activity | nucleus /// cytoplasm | --- | ---
M76180 | dopa decarboxylase (aromatic L-amino acid decarboxylase) | DDC | 3-3 | 0.038749741 | decreased | 4.144759717992855 | 40201_at | 107930 /// 608643 | ENSG00000132437 | 359698 | 1644 | NM_000790 | amino acid metabolism /// catecholamine biosynthesis | aromatic-L-amino-acid decarboxylase activity /// lyase activity | --- | Biogenic_Amine_Synthesis /// Histidine metabolism /// Tyrosine metabolism /// Phenylalanine metabolism /// Tryptophan metabolism /// Indole and ipecac alkaloid biosynthesis /// Alkaloid biosynthesis I | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Biogenic_Amine_Synthesis/Hs_Biogenic_Amine_Synthesis.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00340+4.1.1.28 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00350+4.1.1.28 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00360+4.1.1.28 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+4.1.1.28 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00901+4.1.1.28 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00950+4.1.1.28
[NAME] | chymotrypsin-like | CTRL | 8-3 | 0.036567498 | decreased | 1.323167369104089 | 40205_g_at | 118888 | ENSG00000141086 | 405774 | 1506 | NM_001907 | proteolysis and peptidolysis /// digestion | chymotrypsin activity /// trypsin activity /// peptidase activity | extracellular space | --- | ---
AB014585 | KIAA0685 | KIAA0685 | 10-3 | 0.027679966 | decreased | 1.298025475615288 | 40224_s_at | --- | ENSG00000100239 | 449098 | 9701 | NM_014678 | --- | --- | --- | --- | ---
D29810 | discoidin, CUB and LCCL domain containing 2 | DCBLD2 | 8-3 | 0.042454517 | decreased | 2.409702486759129 | 40227_at | 608698 | ENSG00000057019 | 203691 | 131566 | NM_080927 | cell adhesion /// negative regulation of cell growth /// negative regulation of cell growth /// intracellular receptor-mediated signaling pathway /// intracellular receptor-mediated signaling pathway /// wound healing /// wound healing | protein binding /// protein binding | integral to plasma membrane /// integral to plasma membrane /// cell surface /// cell surface /// integral to membrane | --- | ---
AI743654 | metallophosphoesterase 1 | MPPE1 | 4-10 | 0.02932053 | increased | 1.641912647432924 | 40244_s_at | --- | ENSG00000154889 | 514713 | 65258 | NM_023075 /// NM_138608 | DNA repair | endonuclease activity /// hydrolase activity | --- | --- | ---
U68140 | nuclear VCP-like | NVL | 10-3 | 0.021856485 | decreased | 1.752596992119508 | 40285_at | 602426 | ENSG00000143748 | 497867 | 4931 | NM_002533 /// NM_206840 | --- | ATP binding | nucleus | --- | ---
AF022913 | phosphatidylinositol glycan, class K | PIGK | 2-9 | 0.011490339 | increased | 2.042924945105164 | 40305_r_at | 605087 | ENSG00000142892 | 293653 | 10026 | NM_005482 | proteolysis and peptidolysis | legumain activity | endoplasmic reticulum /// integral to membrane | Ribosomal_Proteins | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Ribosomal_Proteins/Hs_Ribosomal_Proteins.htm
AJ228139 | serine protease inhibitor, [NAME] type 5 | SPINK5 | 8-3 | 0.032636223 | decreased | 1.869010911035027 | 40315_at | 147050 /// 256500 /// 605010 | ENSG00000133710 | 331555 | 11005 | NM_006846 | antimicrobial humoral response (sensu Vertebrata) /// anti-inflammatory response | serine-type endopeptidase inhibitor activity | extracellular region | --- | ---
AF070585 | topoisomerase (DNA) III beta | TOP3B | 1-8 | 0.001369463 | increased | 1.500384565626995 | 40324_r_at | 603582 | ENSG00000100038 | 436401 | 8940 | NM_003935 | DNA topological change /// DNA unwinding /// DNA modification /// chromosome organization and biogenesis (sensu [NAME]) | DNA topoisomerase type I activity | nucleus | --- | ---
J02625 | cytochrome P450, family 2, subfamily E, polypeptide 1 | CYP2E1 | 2-9 | 0.00538337 | increased | 2.545584774560175 | 40379_at | 124040 | ENSG00000130649 | 12907 | 1571 | NM_000773 | electron transport /// transport | oxygen binding /// unspecific monooxygenase activity | endoplasmic reticulum /// microsome /// membrane | Fatty acid metabolism /// gamma-Hexachlorocyclohexane degradation /// Tryptophan metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00071+1.14.14.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00361+1.14.14.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+1.14.14.1
D80003 | nuclear receptor coactivator 6 | NCOA6 | 3-3 | 0.003179952 | decreased | 1.424681518690094 | 40411_at | 605299 | ENSG00000198646 | 368971 | 23054 | NM_014071 | embryonic development (sensu [NAME]) /// DNA replication /// DNA repair /// DNA recombination /// transcription /// regulation of transcription, DNA-dependent /// transcription initiation from RNA polymerase II promoter /// brain development /// heart development /// response to hormone stimulus /// myeloid blood cell differentiation /// estrogen receptor signaling pathway /// glucocorticoid receptor signaling pathway /// positive regulation of transcription from RNA polymerase II promoter | chromatin binding /// protein binding /// transcriptional activator activity /// estrogen receptor binding /// ligand-dependent nuclear receptor transcription coactivator activity /// retinoid X receptor binding /// thyroid hormone receptor binding | nucleus /// nucleus /// transcription factor complex | --- | ---
X16302 | insulin-like growth factor binding protein 2, 36kDa | IGFBP2 | 1-6 | 0.016204846 | increased | 1.88947668199173 | 40422_at | 146731 | ENSG00000115457 | 438102 | 3485 | NM_000597 | regulation of cell growth | insulin-like growth factor binding | extracellular space | Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
D87436 | lipin 2 | LPIN2 | 9-1 | 0.019805498 | decreased | 1.243246946597002 | 40447_at | 605519 | ENSG00000101577 | 268581 | 9663 | NM_014646 | --- | --- | nucleus | --- | ---
X52773 | retinoid X receptor, alpha | RXRA | 10-3 | 0.041203672 | decreased | 1.2164381067639 | 405_at | 180245 | ENSG00000186350 | 20084 | 6256 | NM_002957 | transcription /// regulation of transcription, DNA-dependent /// vitamin metabolism /// signal transduction | transcription factor activity /// steroid hormone receptor activity /// transcription coactivator activity /// retinoid-X receptor activity /// steroid binding | nucleus | Nuclear_Receptors | [NAME]
AF007138 | NDRG family member 4 | NDRG4 | 4-7 | 0.04218407 | increased | 1.778322981228173 | 40500_at | --- | ENSG00000103034 | 322430 | 65009 | NM_020465 /// NM_022910 | response to stress /// cell growth /// cell differentiation | --- | cytoplasm | --- | ---
AF091085 | serologically defined breast cancer antigen 84 | SDBCAG84 | 10-3 | 0.034440235 | decreased | 2.146236181436402 | 40514_at | --- | ENSG00000125991 | 472558 | 51614 | NM_015966 /// NM_198398 | --- | --- | integral to membrane | --- | ---
U28049 | T-box 2 | TBX2 | 1-9 | 0.024826449 | increased | 2.402545989454244 | 40560_at | 600747 | ENSG00000121068 | 531085 | 6909 | NM_005994 | transcription /// regulation of transcription, DNA-dependent /// development | transcription factor activity | nucleus | --- | ---
AI358867 | Apolipoprotein E | APOE | 6-2 | 0.041747074 | decreased | 1.085521678600446 | 40565_at | 104310 /// 107741 /// 269600 | ENSG00000130203 | 515465 | 348 | NM_000041 | response to reactive oxygen species /// lipid transport /// induction of apoptosis /// cytoskeleton organization and biogenesis /// synaptic transmission, cholinergic /// learning and/or memory /// circulation /// regulation of axon extension /// lipoprotein metabolism /// cholesterol homeostasis /// intracellular transport /// regulation of neuronal synaptic plasticity | beta-amyloid binding /// lipid transporter activity /// heparin binding /// lipid binding /// antioxidant activity /// tau protein binding /// apolipoprotein E receptor binding | extracellular region /// extracellular region /// cytoplasm | Statin_Pathway_PharmGKB | [NAME]
AI345337 | [NAME] syndrome 1 | [NAME] | 7-3 | 0.029199496 | decreased | 2.098649125708715 | 40595_at | 154500 /// 606847 | ENSG00000070814 | 519672 | 6949 | NM_000356 /// NM_001008656 /// NM_001008657 | skeletal development /// transport | transporter activity | nucleus /// nucleolus | --- | ---
W27456 | Zinc finger RNA binding protein | ZFR | 9-1 | 0.040937999 | decreased | 2.749088082021388 | 40611_s_at | --- | ENSG00000056097 | 435231 | 51663 | NM_016107 | --- | nucleic acid binding /// zinc ion binding | nucleus | Circadian_Exercise | [NAME]
AI693193 | Metaxin 1 | MTX1 | 2-9 | 0.033747724 | increased | 1.644080711116349 | 40626_at | 600605 | ENSG00000173171 | 490874 | 4580 | NM_002455 /// NM_198883 | protein transport | --- | mitochondrion /// integral to membrane /// outer membrane | --- | ---
[NAME] | phosphatidylinositol glycan, class H | PIGH | 5-3 | 0.038938365 | decreased | 3.102507953594675 | 40629_at | 600154 | ENSG00000100564 | 284157 | 5283 | NM_004569 | protein modification /// GPI anchor biosynthesis | transferase activity, transferring glycosyl groups /// phosphatidylinositol N-acetylglucosaminyltransferase activity | endoplasmic reticulum | --- | ---
AB020634 | nuclear factor of activated T-cells 5, tonicity-responsive | NFAT5 | 1-7 | 0.014555634 | increased | 2.582374251349071 | 40713_at | 604708 | ENSG00000102908 | 371987 | 10725 | [NAME] /// NM_138713 /// NM_138714 /// NM_173214 /// NM_173215 | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// signal transduction /// excretion | transcription factor activity /// RNA polymerase II transcription factor activity | nucleus | --- | ---
AL049274 | MRNA; cDNA DKFZp564H203 (from clone DKFZp564H203) | --- | 10-3 | 0.027799884 | decreased | 2.256081916426551 | 40716_at | --- | --- | 546727 | --- | --- | --- | --- | --- | --- | ---
AF020774 | arachidonate 12-lipoxygenase pseudogene 2 | [NAME] | 3-3 | 0.003641344 | decreased | 1.997758100040659 | 40728_at | --- | --- | 378695 | 245 | XR_000278 | --- | --- | --- | --- | ---
X83228 | cadherin 17, LI cadherin (liver-intestine) | CDH17 | 8-3 | 0.010049237 | decreased | 2.06799144166011 | 40736_at | 603017 | ENSG00000079112 | 89436 | 1015 | NM_004063 | transport /// cell adhesion /// homophilic cell adhesion | transporter activity /// calcium ion binding /// protein binding | membrane fraction /// integral to plasma membrane /// membrane | --- | ---
U19977 | carboxypeptidase A2 (pancreatic) | CPA2 | 10-3 | 0.010664451 | decreased | 2.067042183337199 | 40748_at | 600688 | ENSG00000158516 | 490038 | 1358 | NM_001869 | proteolysis and peptidolysis /// vacuolar protein catabolism | carboxypeptidase activity /// carboxypeptidase A activity /// metallopeptidase activity | --- | --- | ---
AA284298 | hypothetical protein FLJ22269 | FLJ22269 | 6-2 | 0.039494228 | decreased | 1.725764887444235 | 40772_at | --- | ENSG00000169026 | 334789 | 84179 | NM_032219 | --- | --- | integral to membrane | --- | ---
L03785 | [NAME], light polypeptide 5, regulatory | MYL5 | 10-3 | 0.009024099 | decreased | 1.006298267362617 | 40773_at | 160782 | ENSG00000188055 | 410970 | 4636 | NM_002477 | regulation of muscle contraction /// muscle development | motor activity /// calcium ion binding /// structural constituent of muscle | [NAME] /// [NAME] | --- | ---
AF035555 | hydroxyacyl-Coenzyme A dehydrogenase, type II | [NAME] | 3-3 | 0.020754452 | decreased | 2.312389446574309 | 40778_at | 300256 /// 300438 | ENSG00000072506 | 171280 | 3028 | NM_004493 | lipid metabolism /// metabolism | 3-hydroxyacyl-CoA dehydrogenase activity /// alcohol dehydrogenase activity /// 7-alpha-hydroxysteroid dehydrogenase activity /// oxidoreductase activity | mitochondrion /// plasma membrane | --- | ---
AI762021 | Syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) | [NAME] | 9-3 | 0.00261976 | decreased | 1.544306854871748 | 40809_at | 600027 | ENSG00000168807 | 461117 | 6645 | NM_006750 /// NM_130845 | --- | [NAME] binding /// calcium ion binding /// calmodulin binding | membrane fraction /// cytoskeleton /// dystrophin-associated glycoprotein complex /// membrane | --- | ---
AF041081 | hypothetical protein LOC283755 | LOC283755 | 10-3 | 0.036986868 | decreased | 1.580133963914382 | 40878_f_at | --- | --- | --- | 283755 | XR_000150 | --- | --- | --- | --- | ---
AF023158 | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | CDC14B | 8-3 | 0.027803593 | decreased | 1.63790245163688 | 40920_at | 603505 | ENSG00000081377 | 40582 | 8555 | NM_003671 /// NM_033331 /// NM_033332 | protein amino acid dephosphorylation | protein serine/threonine phosphatase activity /// protein tyrosine phosphatase activity /// protein tyrosine/serine/threonine phosphatase activity /// hydrolase activity | nucleus | [NAME] | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm
AI739548 | CDNA FLJ45398 fis, clone BRHIP3027947 | --- | 2-9 | 0.014528959 | increased | 1.541407038210043 | 40921_at | --- | --- | 355443 | --- | --- | --- | --- | --- | --- | ---
AI813651 | Serine threonine kinase 39 (STE20/SPS1 homolog, yeast) | STK39 | 5-4 | 0.006537042 | decreased | 1.95231247433842 | 40967_at | 607648 | ENSG00000198648 | 276271 | 27347 | NM_013233 | protein amino acid phosphorylation /// response to stress | receptor signaling protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity | nucleus /// cytoplasm | --- | ---
U63541 | similar to SRR1-like protein | LOC402055 | 1-8 | 0.007224834 | increased | 2.026972823949848 | 40974_at | --- | --- | 517500 | 402055 | NM_001013694 | rhythmic process | --- | --- | --- | ---
W28830 | serine racemase | SRR | 7-3 | 0.015508922 | decreased | 1.529798137785252 | 40983_s_at | 606477 | ENSG00000167720 | 461954 | 63826 | NM_021947 | amino acid metabolism /// L-serine metabolism /// metabolism | isomerase activity /// racemase and epimerase activity, acting on amino acids and derivatives | --- | --- | ---
AF071309 | mediator of RNA polymerase II transcription, subunit 12 homolog (yeast) | MED12 | 4-7 | 0.031224643 | increased | 1.531198708572167 | 40998_at | 300188 | ENSG00000184634 | 409226 | 9968 | NM_005120 | DNA topological change /// transcription /// regulation of transcription, DNA-dependent /// transcription initiation from RNA polymerase II promoter /// androgen receptor signaling pathway | DNA binding /// DNA topoisomerase (ATP-hydrolyzing) activity /// receptor activity /// ATP binding /// RNA polymerase II transcription mediator activity /// transcriptional activator activity /// ligand-dependent nuclear receptor transcription coactivator activity /// vitamin D receptor binding /// thyroid hormone receptor binding | mediator complex /// nucleus | --- | ---
AI760162 | thioesterase superfamily member 2 | THEM2 | 9-1 | 0.019652266 | decreased | 2.006260216558138 | 41057_at | --- | ENSG00000112304 | 9676 | 55856 | NM_018473 | --- | hydrolase activity | --- | --- | ---
X63575 | ATPase, Ca++ transporting, plasma membrane 2 | ATP2B2 | 8-3 | 0.025557211 | decreased | 1.583000906681453 | 41090_s_at | 108733 | ENSG00000157087 | 268942 | 491 | NM_001001331 /// NM_001683 | cation transport /// calcium ion transport /// metabolism | magnesium ion binding /// calcium-transporting ATPase activity /// calcium ion binding /// calmodulin binding /// ATP binding /// hydrolase activity /// hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | plasma membrane /// integral to membrane | Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
U66359 | G patch domain and KOW motifs | GPKOW | 3-1 | 0.007644098 | decreased | 1.27818772693405 | 41102_at | --- | ENSG00000068394 | 503666 | 27238 | NM_015698 | --- | nucleic acid binding | intracellular | --- | ---
W27452 | hypothetical protein [NAME] | [NAME] | 8-3 | 0.03975415 | decreased | 1.583693742070038 | 41119_f_at | --- | ENSG00000102796 | 266728 | 79758 | NM_024705 | --- | --- | --- | --- | ---
M54927 | proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated) | PLP1 | 7-3 | 0.017120267 | decreased | 1.150458572573227 | 41158_at | 300401 /// 312080 /// 312920 | ENSG00000123560 | 1787 | 5354 | NM_000533 /// NM_199478 | --- | structural molecule activity | integral to membrane | --- | ---
L40410 | thyroid hormone receptor interactor 3 | TRIP3 | 7-4 | 0.00037335 | decreased | 1.609627388414194 | 41251_at | 604500 | ENSG00000108278 | 2210 | 9326 | NM_004773 | regulation of transcription, DNA-dependent | thyroid hormone receptor binding | intracellular | --- | ---
W28614 | --- | --- | 7-3 | 0.018503006 | decreased | 4.271262418062237 | 41252_s_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
AL021707 | GTP binding protein 1 | GTPBP1 | 3-3 | 0.010618316 | decreased | 1.777400090654731 | 41262_at | 602245 | ENSG00000100226 | 276925 | 9567 | NM_004286 | electron transport /// protein biosynthesis /// immune response /// signal transduction | electron transporter activity /// GTP binding | --- | --- | ---
AA908993 | hypothetical protein DKFZp667G2110 | DKFZp667G2110 | 2-9 | 0.037885875 | increased | 2.088252230997851 | 41274_at | --- | ENSG00000080200 | 476970 | 131544 | XM_376254 | --- | sugar binding | --- | --- | ---
[NAME] | UDP glycosyltransferase 2 family, polypeptide B7 | UGT2B7 | 8-3 | 0.016579643 | decreased | 1.24027138354172 | 41376_i_at | 600068 | ENSG00000171234 | 10319 | 7364 | NM_001074 | lipid metabolism /// metabolism | glucuronosyltransferase activity | membrane fraction /// endoplasmic reticulum /// microsome /// integral to membrane | Pentose and glucuronate interconversions /// Androgen and estrogen metabolism /// Starch and sucrose metabolism /// [NAME] and chlorophyll metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00040+2.4.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00150+2.4.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00500+2.4.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00860+2.4.1.17
[NAME] | UDP glycosyltransferase 2 family, polypeptide B7 | UGT2B7 | 2-9 | 0.034792858 | increased | 1.866335338569017 | 41377_f_at | 600068 | ENSG00000171234 | 10319 | 7364 | NM_001074 | lipid metabolism /// metabolism | glucuronosyltransferase activity | membrane fraction /// endoplasmic reticulum /// microsome /// integral to membrane | Pentose and glucuronate interconversions /// Androgen and estrogen metabolism /// Starch and sucrose metabolism /// [NAME] and chlorophyll metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00040+2.4.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00150+2.4.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00500+2.4.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00860+2.4.1.17
AF117829 | receptor-interacting serine-threonine kinase 2 | RIPK2 | 10-3 | 0.013342508 | decreased | 2.38506371041959 | 41384_at | 603455 | ENSG00000104312 | 103755 | 8767 | NM_003821 | protein amino acid phosphorylation /// inflammatory response /// signal transduction /// regulation of apoptosis /// positive regulation of I-kappaB kinase/NF-kappaB cascade | protein serine/threonine kinase activity /// signal transducer activity /// protein binding /// ATP binding /// transferase activity | intracellular | --- | ---
AF055033 | insulin-like growth factor binding protein 5 | IGFBP5 | 1-7 | 0.035479729 | increased | 1.254047140265537 | 41420_at | 146734 | ENSG00000115461 | 369982 | 3488 | NM_000599 | regulation of cell growth /// signal transduction | insulin-like growth factor binding | extracellular region | --- | ---
D78011 | dihydropyrimidinase | DPYS | 8-3 | 0.009633177 | decreased | 1.685501358995667 | 41422_at | 222748 | ENSG00000147647 | 443161 | 1807 | NM_001385 | nucleobase, nucleoside, nucleotide and nucleic acid metabolism /// response to toxin | dihydropyrimidinase activity /// hydrolase activity | --- | Pyrimidine metabolism /// beta-Alanine metabolism /// Pantothenate and CoA biosynthesis | www.genome.ad.jp/dbget-bin/show_pathway?MAP00240+3.5.2.2 /// [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00770+3.5.2.2
AF013588 | mitogen-activated protein kinase kinase 7 | MAP2K7 | 7-3 | 0.015501197 | decreased | 1.732645999883546 | 41444_at | 603014 | --- | 531754 | 5609 | NM_145185 | protein amino acid phosphorylation /// response to stress /// signal transduction | protein serine/threonine kinase activity /// MAP kinase kinase activity /// protein-tyrosine kinase activity /// protein binding /// ATP binding /// transferase activity /// protein kinase binding | --- | MAPK_Cascade | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_MAPK_Cascade/Hs_MAPK_Cascade.htm
U20647 | zinc finger and BTB domain containing 17 | ZBTB17 | 4-5 | 0.033921968 | increased | 2.109346883732623 | 41532_at | 604084 | ENSG00000116809 | 433764 | 7709 | NM_003443 | transcription /// regulation of transcription, DNA-dependent /// negative regulation of cell cycle | transcription factor activity /// protein binding /// zinc ion binding | nucleus | --- | ---
U79298 | hypothetical protein MGC39325 | MGC39325 | 1-8 | 0.000577672 | increased | 2.195959319736945 | 41533_at | --- | ENSG00000169122 | 154652 | 90362 | NM_147189 | --- | --- | --- | --- | ---
D29641 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | SKIV2L2 | 8-3 | 0.01519197 | decreased | 1.284820893569983 | 41557_at | --- | ENSG00000039123 | 274531 | 23517 | NM_015360 | --- | nucleic acid binding /// [NAME] binding /// ATP binding /// ATP-dependent helicase activity /// hydrolase activity | --- | --- | ---
AI467797 | Programmed cell death 2 | PDCD2 | 9-3 | 0.042585733 | decreased | 0.6399608370226665 | 41560_at | 600866 | ENSG00000071994 | 367900 | 5134 | NM_002598 /// NM_144781 | apoptosis /// apoptosis | DNA binding | nucleus /// cytoplasm | --- | ---
X83572 | arylsulfatase D | ARSD | 6-3 | 0.006949394 | decreased | 1.752743591609989 | 41568_at | 300002 | ENSG00000006756 | 528631 | 414 | NM_001669 /// NM_009589 | metabolism | arylsulfatase activity /// calcium ion binding /// sulfuric ester hydrolase activity /// hydrolase activity | lysosome | Androgen and estrogen metabolism /// Glycosphingolipid metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00150+3.1.6.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00600+3.1.6.1
Y15065 | potassium voltage-gated channel, KQT-like subfamily, member 2 | KCNQ2 | 6-3 | 0.024274612 | decreased | 1.843363612524818 | 41589_at | 121200 /// 602235 /// 606437 | ENSG00000075043 | 161851 | 3785 | NM_004518 /// NM_172106 /// NM_172107 /// NM_172108 /// NM_172109 | cation transport /// potassium ion transport /// potassium ion transport /// synaptic transmission /// neurogenesis | voltage-gated potassium channel activity /// voltage-gated potassium channel activity | membrane fraction /// voltage-gated potassium channel complex /// voltage-gated potassium channel complex /// membrane /// integral to membrane | --- | ---
AB007872 | zinc finger protein 264 | ZNF264 | 8-3 | 0.003901999 | decreased | 1.879046824175348 | 41612_at | 604668 | ENSG00000083844 | 515634 | 9422 | NM_003417 | transcription /// regulation of transcription, DNA-dependent | DNA binding /// zinc ion binding | nucleus | --- | ---
AF035625 | serine/threonine kinase 11 (Peutz-Jeghers syndrome) | STK11 | 3-2 | 0.033554578 | decreased | 2.406997352524841 | 41657_at | 175200 /// 602216 | ENSG00000118046 | 515005 | 6794 | NM_000455 | protein amino acid phosphorylation | protein serine/threonine kinase activity /// ATP binding /// transferase activity | --- | --- | ---
U97018 | echinoderm microtubule associated protein like 1 | EML1 | 1-7 | 0.01253601 | increased | 1.671255388053485 | 41671_at | 602033 | ENSG00000066629 | 12451 | 2009 | NM_001008707 /// NM_004434 | visual perception | acid phosphatase activity /// calcium ion binding | microtubule associated complex | --- | ---
AF007128 | F-box and leucine-rich repeat protein 14 | FBXL14 | 9-3 | 0.017117989 | decreased | 1.171680760470691 | 41672_at | 609081 | ENSG00000171823 | 367956 | 144699 | NM_152441 | ubiquitin cycle | --- | --- | --- | ---
AF035282 | chromosome 1 open reading frame 21 | C1orf21 | 8-3 | 0.017084028 | decreased | 1.8803698223253 | 41679_at | --- | ENSG00000116667 | 132369 | 81563 | NM_030806 | --- | --- | --- | --- | ---
AL079277 | hypothetical protein LOC54103 | LOC54103 | 7-3 | 0.017724885 | decreased | 1.645672120856586 | 41710_at | --- | ENSG00000135174 | 186649 | 54103 | XM_379881 /// XM_499340 | --- | --- | --- | --- | ---
AB007924 | plasticity related gene 1 | LPPR4 | 2-8 | 0.032996315 | increased | 1.856204503493978 | 41714_at | 607813 | ENSG00000117600 | 13245 | 9890 | NM_014839 | --- | hydrolase activity | integral to membrane | --- | ---
U53003 | chromosome 21 open reading frame 33 | C21orf33 | 3-1 | 0.011118248 | decreased | 1.428947001472815 | 41749_at | 601659 | ENSG00000160221 | 413482 | 8209 | NM_004649 /// NM_198155 | --- | --- | cell wall /// mitochondrion | --- | ---
U79278 | protein disulfide isomerase-associated 6 | PDIA6 | 10-3 | 0.044160662 | decreased | 1.10430966471675 | 41751_at | --- | ENSG00000143870 | 212102 | 10130 | NM_005742 | electron transport /// protein folding | protein disulfide isomerase activity /// electron transporter activity /// isomerase activity | endoplasmic reticulum | --- | ---
AA978033 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | COX7A2 | 10-3 | 0.004048632 | decreased | 2.184069849455973 | 41760_at | 123996 | ENSG00000112695 | 70312 | 1347 | NM_001865 | electron transport | cytochrome-c oxidase activity /// electron transporter activity /// oxidoreductase activity | mitochondrion /// inner membrane | Electron_Transport_Chain /// Oxidative phosphorylation | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00190+1.9.3.1
U96781 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | ATP2A1 | 8-3 | 0.002090971 | decreased | 1.820566525804297 | 41769_at | 108730 /// 601003 | ENSG00000196296 | 550464 | 487 | NM_004320 /// NM_173201 | cation transport /// calcium ion transport /// regulation of striated muscle contraction /// metabolism /// proton transport | magnesium ion binding /// calcium-transporting ATPase activity /// calcium ion binding /// ATP binding /// hydrolase activity /// hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | smooth endoplasmic reticulum /// membrane /// integral to membrane | --- | ---
L78243 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | ABCC8 | 1-9 | 0.024429427 | increased | 1.357456365719765 | 41792_at | 256450 /// 600509 | ENSG00000006071 | 54470 | 6833 | NM_000352 | carbohydrate metabolism /// transport /// potassium ion transport | nucleotide binding /// receptor activity /// ATP binding /// sulfonylurea receptor activity /// potassium ion transporter activity /// ATPase activity /// ATPase activity, coupled to transmembrane movement of substances | membrane /// integral to membrane | --- | ---
AF052097 | F-box and leucine-rich repeat protein 5 | FBXL5 | 10-3 | 0.024618667 | decreased | 2.031028707437874 | 41801_at | 605655 | ENSG00000118564 | 479208 | 26234 | NM_012161 /// NM_033535 | protein ubiquitination | ubiquitin-protein ligase activity | ubiquitin ligase complex | --- | ---
AF060503 | zinc finger protein 324 | ZNF324 | 7-4 | 0.034781152 | decreased | 1.406824840678022 | 41822_at | --- | ENSG00000083812 | 515660 | 25799 | NM_014347 | transcription /// regulation of transcription, DNA-dependent | DNA binding /// zinc ion binding | nucleus | --- | ---
AB016492 | jumping translocation breakpoint | JTB | 5-3 | 0.013029529 | decreased | 2.354935179906154 | 41834_g_at | 604671 | ENSG00000143543 | 6396 | 10899 | NM_006694 | --- | --- | membrane fraction /// integral to plasma membrane /// integral to membrane | --- | ---
X99270 | three prime repair exonuclease 2 | TREX2 | 2-9 | 0.037448353 | increased | 2.17150967662845 | 41838_at | 300370 | --- | 170835 | 11219 | --- | DNA repair | magnesium ion binding /// exonuclease activity /// 3'-5'-exodeoxyribonuclease activity /// exodeoxyribonuclease III activity /// hydrolase activity | nucleus | --- | ---
W27605 | Cone-rod homeobox | CRX | 6-2 | 0.02261835 | decreased | 3.023773702095803 | 41846_at | 120970 /// 204000 /// 268000 /// 602225 | ENSG00000105392 | 249186 | 1406 | NM_000554 | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// sensory perception /// visual perception /// organogenesis | transcription factor activity | nucleus | --- | ---
AI824126 | Hepatitis delta antigen-interacting protein A | DIPA | 8-3 | 0.001060852 | decreased | 1.358798458422384 | 41851_at | 605360 | ENSG00000175602 | 66713 | 11007 | NM_006848 | --- | --- | --- | --- | ---
AL050019 | DKFZP564C186 protein | DKFZP564C186 | 6-2 | 0.012717869 | decreased | 1.528096761028631 | 41861_at | --- | ENSG00000188976 | 335293 | 26155 | NM_015658 | --- | --- | nucleus | --- | ---
AF022728 | dystrobrevin, beta | DTNB | 10-3 | 0.01177633 | decreased | 1.673851662107719 | 41866_s_at | 602415 | ENSG00000138101 | 307720 | 1838 | NM_021907 /// NM_033147 /// NM_033148 /// NM_183360 /// NM_183361 | --- | calcium ion binding /// protein binding /// zinc ion binding | cytoskeleton | --- | ---
U68030 | chemokine (C-C motif) receptor 6 | CCR6 | 10-3 | 0.030147869 | decreased | 1.881821271046615 | 458_at | 601835 | ENSG00000112486 | 46468 | 1235 | NM_004367 /// NM_031409 | cell motility /// chemotaxis /// humoral immune response /// cellular defense response /// signal transduction /// G-protein coupled receptor protein signaling pathway /// positive regulation of cytosolic calcium ion concentration /// antimicrobial humoral response (sensu Vertebrata) | rhodopsin-like receptor activity /// receptor activity /// angiotensin type II receptor activity /// C-C chemokine receptor activity | plasma membrane /// integral to plasma membrane | Peptide_GPCRs /// GPCRDB_Class_A_Rhodopsin-like | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm
U51127 | interferon regulatory factor 5 | IRF5 | 2-9 | 0.029602917 | increased | 2.507337654385036 | 477_at | 607218 | ENSG00000128604 | 521181 | 3663 | NM_002200 /// NM_032643 | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// RNA polymerase III transcription factor activity | nucleus | Apoptosis | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm
U60521 | caspase 9, apoptosis-related cysteine protease | CASP9 | 10-3 | 0.013056937 | decreased | 2.16341735305112 | 486_at | 602234 | ENSG00000132906 | 329502 | 842 | NM_001229 /// NM_032996 | proteolysis and peptidolysis /// apoptotic program /// caspase activation via cytochrome c /// regulation of apoptosis | protein binding /// enzyme activator activity /// caspase activity | intracellular | Apoptosis /// Apoptosis_GenMAPP /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_GenMAPP/Hs_Apoptosis_GenMAPP.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
U46116 | protein tyrosine phosphatase, receptor type, G | PTPRG | 2-9 | 0.007470433 | increased | 1.94900147023159 | 491_at | 176886 | ENSG00000144724 | 386866 | 5793 | NM_002841 | protein amino acid dephosphorylation /// one-carbon compound metabolism /// transmembrane receptor [NAME] signaling pathway | carbonate dehydratase activity /// transmembrane receptor protein tyrosine phosphatase activity /// zinc ion binding /// hydrolase activity | integral to plasma membrane | --- | ---
M24902 | acid phosphatase, prostate | ACPP | 2-9 | 0.01622349 | increased | 1.875359663192862 | 617_at | 171790 | ENSG00000014257 | 433060 | 55 | NM_001099 | regulation of cell cycle | acid phosphatase activity /// protein tyrosine phosphatase activity /// hydrolase activity | extracellular region | [NAME] degradation /// [NAME] metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00361+3.1.3.2 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00740+3.1.3.2
L20965 | phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) | PDE4A | 5-2 | 0.02052186 | decreased | 1.518438491589321 | 666_at | 600126 | ENSG00000065989 | 89901 | 5141 | NM_006202 | signal transduction /// signal transduction /// cyclic nucleotide metabolism | catalytic activity /// 3',5'-cyclic-nucleotide phosphodiesterase activity /// cAMP-specific phosphodiesterase activity /// cAMP-specific phosphodiesterase activity /// hydrolase activity | membrane fraction /// soluble fraction /// insoluble fraction | G_Protein_Signaling /// Purine metabolism | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+3.1.4.17
L05072 | interferon regulatory factor 1 | IRF1 | 10-3 | 0.022603106 | decreased | 2.357768192901946 | 669_s_at | 137215 /// 147575 /// 153550 | ENSG00000125347 | 436061 | 3659 | NM_002198 | transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// immune response /// cell cycle /// negative regulation of cell cycle | transcription factor activity | nucleus | Apoptosis | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm
[NAME] | endogenous retroviral sequence K, 6 | ERVK6 | 8-3 | 0.043110593 | decreased | 1.140960587687285 | 686_s_at | 605626 | ENSG00000196413 | --- | 64006 | NM_001007236 | RNA-dependent DNA replication /// DNA transposition /// proteolysis and peptidolysis /// viral life cycle | nucleic acid binding /// [NAME] binding /// RNA-directed DNA polymerase activity /// aspartic-type endopeptidase activity /// peptidase activity /// transferase activity | intracellular /// membrane /// viral capsid | --- | ---
HG2689-HT2785 | --- | --- | 1-7 | 0.016827269 | increased | 1.418956696993656 | 694_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
HG2157-HT2227 | --- | --- | 3-3 | 0.038397196 | decreased | 3.778594477129953 | 734_at | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
[NAME] | 5'-nucleotidase, cytosolic II | [NAME] | 1-7 | 0.02221534 | increased | 2.123911263134276 | 738_at | 600417 | ENSG00000076685 | 158209 | 22978 | NM_012229 | --- | 5'-nucleotidase activity /// hydrolase activity | [NAME] | --- | ---
D78586 | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | CAD | 4-10 | 0.015810731 | increased | 2.004279844926679 | 749_at | 114010 | ENSG00000084774 | 377010 | 790 | NM_004341 | 'de novo' pyrimidine base biosynthesis /// pyrimidine nucleotide biosynthesis /// amino acid metabolism /// arginine biosynthesis /// glutamine metabolism /// nitrogen compound metabolism /// biosynthesis | aspartate carbamoyltransferase activity /// carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity /// dihydroorotase activity /// ATP binding /// amino acid binding /// transferase activity /// hydrolase activity /// ligase activity | cytoplasm | Pyrimidine metabolism /// Glutamate metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00240+6.3.5.5 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00251+6.3.5.5
D85418 | phosphatidylinositol glycan, class C | PIGC | 3-1 | 0.024964113 | decreased | 1.947381845706707 | 751_at | 601730 | ENSG00000135845 | 188456 | 5279 | NM_002642 /// NM_153747 | GPI anchor biosynthesis | transferase activity, transferring glycosyl groups /// phosphatidylinositol N-acetylglucosaminyltransferase activity | endoplasmic reticulum membrane /// integral to membrane | --- | ---
X62055 | protein tyrosine phosphatase, non-receptor type 6 | [NAME] | 3-1 | 0.011901765 | decreased | 2.994027816266733 | 794_at | 176883 | ENSG00000111679 | 63489 | 5777 | NM_002831 /// NM_080548 /// NM_080549 | protein amino acid dephosphorylation /// protein amino acid dephosphorylation /// apoptosis /// G-protein coupled receptor protein signaling pathway /// intracellular signaling cascade /// negative regulation of cell proliferation | protein tyrosine phosphatase activity /// protein tyrosine phosphatase activity /// hydrolase activity | cytoskeleton /// membrane | --- | ---
X84002 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa | TAF12 | 10-3 | 0.030597102 | decreased | 1.346649294138187 | 802_at | 600773 | ENSG00000120656 | 530251 | 6883 | NM_005644 | transcription /// transcription initiation /// regulation of transcription, DNA-dependent | DNA binding /// protein binding /// general [NAME] polymerase II transcription factor activity | nucleus /// transcription factor TFIID complex | RNA_transcription_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_RNA_transcription_Reactome/Hs_RNA_transcription_Reactome.htm
U39317 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | UBE2D2 | 3-3 | 0.024639302 | decreased | 1.447111259829762 | 832_at | 602962 | ENSG00000131508 | 108332 | 7322 | NM_003339 /// NM_181838 | ubiquitin cycle | ubiquitin conjugating enzyme activity /// ubiquitin-protein ligase activity /// ligase activity | --- | Proteasome_Degradation /// Ubiquitin mediated proteolysis | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP04120+6.3.2.19
U48251 | protein kinase C binding protein 1 | [NAME] | 4-10 | 0.032115894 | increased | 1.722692822766355 | 842_at | --- | ENSG00000101040 | 446240 | 23613 | NM_012408 /// NM_183047 /// NM_183048 | regulation of transcription, DNA-dependent /// cell cycle | DNA binding | --- | --- | ---
U16811 | BCL2-antagonist/killer 1 | BAK1 | 10-3 | 0.01506716 | decreased | 1.531998031432797 | 846_s_at | 600516 | ENSG00000030110 | 485139 | 578 | NM_001188 | induction of apoptosis /// apoptotic mitochondrial changes /// regulation of apoptosis | protein heterodimerization activity | integral to membrane | Apoptosis /// Apoptosis_GenMAPP | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_GenMAPP/Hs_Apoptosis_GenMAPP.htm
M26679 | homeo box A5 | HOXA5 | 8-3 | 0.011312048 | decreased | 2.338586371357347 | 873_at | 142952 | ENSG00000106004 | 37034 | 3202 | NM_019102 | regulation of transcription, DNA-dependent /// development | transcription factor activity | nucleus | --- | ---
J03910 | metallothionein 1G | [NAME] | 9-1 | 0.023844629 | decreased | 1.420158895134751 | 926_at | 156353 | ENSG00000125144 | 433391 | 4495 | NM_005950 | --- | metal ion binding | --- | --- | ---