Spreadsheet: 415858e1-2f7b-40b6-add9-40f36a47fbd9
Sheet: Sheet1

Unnamed: 0 | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4
Supplementary table 3 | GO/KEGG enriched in down-regulated genes (FDR<=0.1, 343 genes)
GO/KEGG term | P-value | Fold change | Gene IDs | Gene symbols
GO:0003735|structural constituent of ribosome | 3.86398626361e-14 | 10.4213581262 | 6154,6155,6157,84545,11224,6203,6208,6143,6141,64981,6218,6133,6136,65008,6223,9045,6125,6124,6169,6168,6160,6166,6189 | RPL26,RPL27,RPL27A,MRPL43,RPL35,RPS9,RPS14,RPL19,RPL18,MRPL34,RPS17,RPL9,RPL12,MRPL1,RPS19,RPL14,RPL5,RPL4,RPL38,RPL37A,RPL31,RPL36AL,RPS3A
GO:0006414|translational elongation | 7.71734573426e-14 | 13.5160483871 | 6154,6155,6157,11224,6203,6208,6143,6141,6218,6133,6136,6223,9045,6125,6124,6169,6168,6160,6189 | RPL26,RPL27,RPL27A,RPL35,RPS9,RPS14,RPL19,RPL18,RPS17,RPL9,RPL12,RPS19,RPL14,RPL5,RPL4,RPL38,RPL37A,RPL31,RPS3A
GO:0005840|ribosome | 1.08010966174e-13 | 8.89213709677 | 6154,6155,6157,84545,11224,6203,6208,6143,6141,64981,28957,6218,6133,6136,65008,6223,9045,6125,6124,6169,6168,6160,6166,6189 | RPL26,RPL27,RPL27A,MRPL43,RPL35,RPS9,RPS14,RPL19,RPL18,MRPL34,MRPS28,RPS17,RPL9,RPL12,MRPL1,RPS19,RPL14,RPL5,RPL4,RPL38,RPL37A,RPL31,RPL36AL,RPS3A
GO:0033279|ribosomal subunit | 2.16540441979e-11 | 10.5823780325 | 6154,6157,11224,6203,6208,6143,6141,64981,28957,6218,65008,6223,9045,6125,6124,6169,6160,6189 | RPL26,RPL27A,RPL35,RPS9,RPS14,RPL19,RPL18,MRPL34,MRPS28,RPS17,MRPL1,RPS19,RPL14,RPL5,RPL4,RPL38,RPL31,RPS3A
GO:0015934|large ribosomal subunit | 8.76022890519e-09 | 13.7684703434 | 6154,6157,11224,6143,6141,64981,65008,9045,6125,6124,6169,6160 | RPL26,RPL27A,RPL35,RPL19,RPL18,MRPL34,MRPL1,RPL14,RPL5,RPL4,RPL38,RPL31
GO:0022625|cytosolic large ribosomal subunit | 8.76022890519e-09 | 19.7603046595 | 6154,6157,11224,6143,6141,9045,6125,6124,6169,6160 | [NAME]
GO:0044445|cytosolic part | 3.49030696237e-07 | 7.25888742594 | 6154,6157,11224,6203,6208,6143,6141,6218,6223,9045,6125,6124,6169,6160,6189 | RPL26,RPL27A,RPL35,RPS9,RPS14,RPL19,RPL18,RPS17,RPS19,RPL14,RPL5,RPL4,RPL38,RPL31,RPS3A
GO:0034645|cellular macromolecule biosynthetic process | 1.72177252996e-06 | 3.2482692591 | 6154,6155,6157,286826,84545,11224,6203,6208,10849,4666,56953,6143,6141,64981,6218,6133,6136,65008,5610,2069,6223,9045,6125,6124,1854,6169,6168,6160,6166,6189 | RPL26,RPL27,RPL27A,LIN9,MRPL43,RPL35,RPS9,RPS14,CD3EAP,NACA,NT5M,RPL19,RPL18,MRPL34,RPS17,RPL9,RPL12,MRPL1,EIF2AK2,EREG,RPS19,RPL14,RPL5,RPL4,DUT,RPL38,RPL37A,RPL31,RPL36AL,RPS3A
GO:0009059|macromolecule biosynthetic process | 4.43120882317e-06 | 3.09740624561 | 6154,6155,6157,286826,84545,11224,6203,6208,10849,4666,56953,6143,6141,64981,6218,6133,6136,65008,5610,2069,6223,9045,6125,6124,1854,6169,6168,6160,6166,6189 | RPL26,RPL27,RPL27A,LIN9,MRPL43,RPL35,RPS9,RPS14,CD3EAP,NACA,NT5M,RPL19,RPL18,MRPL34,RPS17,RPL9,RPL12,MRPL1,EIF2AK2,EREG,RPS19,RPL14,RPL5,RPL4,DUT,RPL38,RPL37A,RPL31,RPL36AL,RPS3A
GO:0005198|structural molecule activity | 1.22554254811e-05 | 3.17471340976 | 6154,6155,6157,84545,11224,6203,6208,51807,6143,6141,64981,6218,6133,6136,7060,65008,6223,9045,6125,6124,6169,6168,6160,6166,7169,6189,10174 | RPL26,RPL27,RPL27A,MRPL43,RPL35,RPS9,RPS14,TUBA8,RPL19,RPL18,MRPL34,RPS17,RPL9,RPL12,THBS4,MRPL1,RPS19,RPL14,RPL5,RPL4,RPL38,RPL37A,RPL31,RPL36AL,[NAME],SORBS3
GO:0030529|ribonucleoprotein complex | 1.45226138234e-05 | 3.42829382044 | 6154,6155,6157,84545,11224,6203,6208,6143,6141,64981,28957,6218,6133,6136,65008,6223,9045,6125,6124,6169,6168,6160,6166,6189 | RPL26,RPL27,RPL27A,MRPL43,RPL35,RPS9,RPS14,RPL19,RPL18,MRPL34,MRPS28,RPS17,RPL9,RPL12,MRPL1,RPS19,RPL14,RPL5,RPL4,RPL38,RPL37A,RPL31,RPL36AL,RPS3A
GO:0005622|intracellular | 0.000406325942566 | 1.89550257862 | [NAME] | RPL26,RPL27,RPL27A,SOLH,CAPN10,ZNF471,SFRS14,GNL3L,ZNF460,RPL35,CAV2,RPS9,RPS14,ZNF669,ARID5B,ZNF132,ZNF557,RPL19,RPL18,ZNF600,ZNF320,MRPL34,RPS17,PLEKHG6,RPL9,CNP,ZBTB8A,MRPL1,ZNF346,EIF2AK2,ZFP14,ZNF480,RPS19,RPL14,SLFN13,RPL5,RPL4,CFL2,GTPBP6,ZNF618,GLTSCR2,ZNF454,ZNF626,RPL38,RPL37A,RPL31,RPL36AL,[NAME],MCPH1,ZNF581
GO:0005829|cytosol | 0.00047469763571 | 2.14881532386 | 6154,6155,6157,11132,5577,11224,858,6203,6208,8718,1830,6718,6143,6141,6218,6133,6136,8436,3002,8666,51559,6223,9045,353,6125,6124,5478,6647,54751,5901,10380,1854,2176,23175,6169,6168,6160,6189 | RPL26,RPL27,RPL27A,CAPN10,PRKAR2B,RPL35,CAV2,RPS9,RPS14,TNFRSF25,DSG3,AKR1D1,RPL19,RPL18,RPS17,RPL9,RPL12,SDPR,GZMB,EIF3G,NT5DC3,RPS19,RPL14,APRT,RPL5,RPL4,PPIA,SOD1,FBLIM1,RAN,BPNT1,DUT,FANCC,LPIN1,RPL38,RPL37A,RPL31,RPS3A
GO:0006364|rRNA processing | 0.000549248072857 | 6.66910282258 | 90121,6154,6208,6218,317781,6223,9045,24140,6125 | TSR2,RPL26,RPS14,RPS17,DDX51,RPS19,RPL14,FTSJ1,RPL5
GO:0044249|cellular biosynthetic process | 0.000549248072857 | 2.09701192305 | 6154,6155,6157,286826,84545,108,11224,6203,6208,10849,4666,56953,6718,6143,6141,5498,64981,6218,10476,6133,6136,65008,1544,5610,2069,5027,6223,9045,353,6125,6124,6647,1854,6169,6168,6160,6166,6189,477 | RPL26,RPL27,RPL27A,LIN9,MRPL43,ADCY2,RPL35,RPS9,RPS14,CD3EAP,NACA,NT5M,AKR1D1,RPL19,RPL18,PPOX,MRPL34,RPS17,ATP5H,RPL9,RPL12,MRPL1,CYP1A2,EIF2AK2,EREG,P2RX7,RPS19,RPL14,APRT,RPL5,RPL4,SOD1,DUT,RPL38,RPL37A,RPL31,RPL36AL,RPS3A,ATP1A2
GO:0016072|rRNA metabolic process | 0.000719542813759 | 6.40233870968 | 90121,6154,6208,6218,317781,6223,9045,24140,6125 | TSR2,RPL26,RPS14,RPS17,DDX51,RPS19,RPL14,FTSJ1,RPL5
GO:0022613|ribonucleoprotein complex biogenesis | 0.00158005856015 | 9.92610652663 | 6154,54552,6218,6223,9045,6125 | RPL26,GNL3L,RPS17,RPS19,RPL14,RPL5
GO:0009058|biosynthetic process | 0.00158005856015 | 1.96511317056 | 6154,6155,6157,286826,84545,108,11224,6203,6208,10849,4666,56953,6718,6143,6141,5498,64981,6218,10476,6133,6136,65008,1544,5610,2069,5027,6223,9045,353,6125,6124,6647,1854,84681,6169,6168,6160,6166,6189,477 | RPL26,RPL27,RPL27A,LIN9,MRPL43,ADCY2,RPL35,RPS9,RPS14,CD3EAP,NACA,NT5M,AKR1D1,RPL19,RPL18,PPOX,MRPL34,RPS17,ATP5H,RPL9,RPL12,MRPL1,CYP1A2,EIF2AK2,EREG,P2RX7,RPS19,RPL14,APRT,RPL5,RPL4,SOD1,DUT,HINT2,RPL38,RPL37A,RPL31,RPL36AL,RPS3A,ATP1A2
GO:0044085|cellular component biogenesis | 0.00222032084457 | 9.27875175316 | 6154,54552,6218,6223,9045,6125 | RPL26,GNL3L,RPS17,RPS19,RPL14,RPL5
GO:0044444|cytoplasmic part | 0.00537190392181 | 1.39512998781 | 710,6154,6155,6157,84545,292,11132,55830,4353,5577,1511,84129,11224,858,6203,6208,2681,8718,192134,1991,23509,999,169026,4666,1191,1830,56953,55333,6718,6143,6141,5498,55803,64981,29841,387914,5037,2021,28957,28958,6218,10476,6133,6136,7060,1267,65008,1544,2244,8436,8029,9173,23463,51599,150274,23531,3002,1350,2109,8666,51559,51001,6223,84174,9045,353,6125,6124,5473,5478,6647,54751,5901,6391,10380,2781,1854,6517,2176,23177,23175,309,387849,378884,84681,6169,6168,6160,6166,84814,7169,136991,6189,79648,477,9694 | SERPING1,RPL26,RPL27,RPL27A,MRPL43,SLC25A5,CAPN10,GLT8D1,MPO,PRKAR2B,CTSG,ACAD11,RPL35,CAV2,RPS9,RPS14,GGTA1,TNFRSF25,B3GNT6,ELANE,POFUT1,CDH1,SLC30A8,NACA,CLU,DSG3,NT5M,SYNJ2BP,AKR1D1,RPL19,RPL18,PPOX,ADAP2,MRPL34,GRHL1,SHISA2,PEBP1,ENDOG,MRPS28,CCDC56,RPS17,ATP5H,RPL9,RPL12,THBS4,CNP,[NAME],SDPR,CUBN,IL1RL1,ICMT,LSR,HSCB,MMD,GZMB,COX7C,ETFB,EIF3G,NT5DC3,MTERFD1,RPS19,SLA2,RPL14,APRT,RPL5,RPL4,PPBP,PPIA,SOD1,FBLIM1,RAN,SDHC,BPNT1,GNAZ,DUT,SLC2A4,FANCC,CEP68,LPIN1,ANXA6,REP15,NHLRC1,HINT2,RPL38,RPL37A,RPL31,RPL36AL,PPAPDC3,TPM2,ASZ1,RPS3A,MCPH1,ATP1A2,TTC35
GO:0022627|cytosolic small ribosomal subunit | 0.00856656028449 | 9.36014431239 | 6203,6208,6218,6223,6189 | RPS9,RPS14,RPS17,RPS19,RPS3A
GO:0015935|small ribosomal subunit | 0.0095355923502 | 6.99709148599 | 6203,6208,28957,6218,6223,6189 | RPS9,RPS14,MRPS28,RPS17,RPS19,RPS3A
GO:0043232|intracellular non-membrane-bounded organelle | 0.0105424787719 | 1.68588688903 | 6154,6155,6157,84545,292,11130,54552,11224,6203,6208,10849,999,6143,6141,3014,64981,29841,28957,6218,55200,317781,6133,6136,3652,65008,23567,9173,51599,6223,9045,6125,6124,1073,54751,29997,23177,6169,6168,6160,6166,4603,7169,136991,6189,79648,10174 | RPL26,RPL27,RPL27A,MRPL43,SLC25A5,ZWINT,GNL3L,RPL35,RPS9,RPS14,CD3EAP,CDH1,RPL19,RPL18,H2AFX,MRPL34,GRHL1,MRPS28,RPS17,PLEKHG6,DDX51,RPL9,RPL12,IPP,MRPL1,ZNF346,IL1RL1,LSR,RPS19,RPL14,RPL5,RPL4,CFL2,FBLIM1,GLTSCR2,CEP68,RPL38,RPL37A,RPL31,RPL36AL,MYBL1,TPM2,ASZ1,RPS3A,MCPH1,SORBS3
GO:0043228|non-membrane-bounded organelle | 0.0105424787719 | 1.68588688903 | 6154,6155,6157,84545,292,11130,54552,11224,6203,6208,10849,999,6143,6141,3014,64981,29841,28957,6218,55200,317781,6133,6136,3652,65008,23567,9173,51599,6223,9045,6125,6124,1073,54751,29997,23177,6169,6168,6160,6166,4603,7169,136991,6189,79648,10174 | RPL26,RPL27,RPL27A,MRPL43,SLC25A5,ZWINT,GNL3L,RPL35,RPS9,RPS14,CD3EAP,CDH1,RPL19,RPL18,H2AFX,MRPL34,GRHL1,MRPS28,RPS17,PLEKHG6,DDX51,RPL9,RPL12,IPP,MRPL1,ZNF346,IL1RL1,LSR,RPS19,RPL14,RPL5,RPL4,CFL2,FBLIM1,GLTSCR2,CEP68,RPL38,RPL37A,RPL31,RPL36AL,MYBL1,TPM2,ASZ1,RPS3A,MCPH1,SORBS3
GO:0031093|platelet alpha granule lumen | 0.0105424787719 | 8.67525570417 | 710,1191,7060,2244,5473 | SERPING1,CLU,THBS4,FGB,PPBP
GO:0042273|ribosomal large subunit biogenesis | 0.0116922853069 | 21.3411290323 | 6154,9045,6125 | RPL26,RPL14,RPL5
GO:0060205|cytoplasmic membrane-bounded vesicle lumen | 0.0134607971256 | 8.08376099707 | 710,1191,7060,2244,5473 | SERPING1,CLU,THBS4,FGB,PPBP
GO:0031983|vesicle lumen | 0.016013717976 | 7.73229312763 | 710,1191,7060,2244,5473 | SERPING1,CLU,THBS4,FGB,PPBP
GO:0002262|myeloid cell homeostasis | 0.0200305824054 | 47.4247311828 | 6647,2176 | SOD1,FANCC
GO:0003723|RNA binding | 0.0214695966093 | 2.14679853091 | 6154,6157,10147,11224,6203,6208,6143,6141,317781,6133,6136,65008,23567,5610,8666,6223,9045,6125,6124,6169,6160,6189 | RPL26,RPL27A,SFRS14,RPL35,RPS9,RPS14,RPL19,RPL18,DDX51,RPL9,RPL12,MRPL1,ZNF346,EIF2AK2,EIF3G,RPS19,RPL14,RPL5,RPL4,RPL38,RPL31,RPS3A
GO:0045182|translation regulator activity | 0.0250980356947 | 9.48494623656 | 84545,6203,6208,64981 | MRPL43,RPS9,RPS14,MRPL34
GO:0031640|killing of cells of another organism | 0.0276410467706 | 15.2436635945 | 1669,8542,10578 | DEFA4,APOL1,GNLY
GO:0016266|O-glycan processing | 0.0348783309398 | 35.5685483871 | 192134,23509 | B3GNT6,POFUT1
GO:0034470|ncRNA processing | 0.0438819912302 | 3.36965195246 | 90121,6154,6208,6218,317781,6223,9045,24140,6125 | TSR2,RPL26,RPS14,RPS17,DDX51,RPS19,RPL14,FTSJ1,RPL5
GO:0034660|ncRNA metabolic process | 0.0495839101588 | 3.05309428215 | 90121,6154,6208,6218,317781,6223,9045,24140,6125,136991 | TSR2,RPL26,RPS14,RPS17,DDX51,RPS19,RPL14,FTSJ1,RPL5,ASZ1
03010|Ribosome | 2.03411885462e-08 | 8.14005847953 | 6154,6155,6157,11224,6203,6143,6141,6133,6136,9045,6169,6168,6160,6166 | RPL26,RPL27,RPL27A,RPL35,RPS9,RPL19,RPL18,RPL9,RPL12,RPL14,RPL38,RPL37A,RPL31,RPL36AL