Spreadsheet: 9f4dc2d5-471a-41c1-a75c-4f0b7f2aa060
Sheet: Sheet1

Table S3: Campylobacter jejuni, Campylobacter coli, Campylobacter lari, and Campylobacter upsaliensis restriction-modification (R/M) systems | Unnamed: 1 | Unnamed: 2
C. jejuni RM1221:
Gene(s) | Type | Comment/description
CJE1720-CJE1724 | I | hsdR1/rloC/hsdS2/mloA/hsdM1 (Type IAB family).
CJE0031 | IIS | Cj0031/32 homolog: Poly GC tract mutated to fuse ORFs.
CJE0789 | IIS | Cj0690c homolog.
CJE1195 | II | Cj1051c homolog: Encodes CjeI.
CJE0731 | III | III (mod-1): Similar to Helicobacter pylori J99 ORF JHP1296.
CJE0732 | III | III (res-1): Similar to Helicobacter pylori J99 ORF JHP1297
CJE0134 |  | Cj0139 homolog: [NAME] endonuclease.
CJE1061 |  | Cj0979c homolog: Putative endonuclease.
CJE0150 |  | Cj0154c homolog: Methyltransferase.
CJE0201 |  | Cj0208 homolog: Methyltransferase (Methylates EcoRI restriction sites).
CJE0310 |  | Methyltransferase.
CJE1635 |  | Cj1461 homolog: Methyltransferase
C. jejuni NCTC 11168:
Gene(s) | Type | Comment/description
Cj1549c-Cj1553c | I | hsdR3/rloH/hsdS8/mloB/hsdM3 (Type IF family).
Cj0031/32 | IIS | Fused by slipped strand mispairing (G10 - split, G9 - fused).
Cj0690c | IIS | Putative.
Cj1051c | II | Encodes CjeI.
Cj0139 |  | [NAME] endonuclease.
Cj0979c |  | Putative endonuclease.
Cj0154c |  | Methyltransferase.
Cj0208 |  | Methyltransferase (Methylates EcoRI restriction sites).
Cj1461 |  | Methyltransferase.
C. lari RM2100:
Gene(s) | Type | Comment/description
CLA0703-CLA0708 | I | hsdR1/rloEK/hsdS13/mloC/hsdM1 (Type IAB family; hsdS13 has hsdS10 CRD).
CLA0228 | IIS | Cj0031/32 homolog: Poly GC tract mutated to fuse ORFs.
CLA0922 | IIS | Cj0031/32 homolog: Poly GC tract mutated to fuse ORFs.
CLA0929 |  | Cj0979c homolog: Putative endonuclease.
CLA1253 |  | Putative endonuclease.
CLA0268 |  | Cj0154c homolog: Methyltransferase.
CLA0077 |  | Cj0208 homolog: Methyltransferase (Methylates EcoRI restriction sites).
CLA0763 |  | Cj1461 homolog: Methyltransferase.
C. upsaliensis RM3195:
Gene(s) | Type | Comment/description
CUP0198-CUP0200 | I | hsdM1/hsdS1/hsdR1 (Type IG family).
CUP1004-CUP1007 | I | hsdS2/hsdM2/hsdR2 (Type IA family).
CUP1391-CUP1393 | I | hsdM3/hsdR3/hsdS3 (Type IC family; hsdM has 15 bp GC tract).
CUP1744-CUP1746 | I | hsdM4/hsdS4 (Type IH family).
CUP1058/CUP1059 | IIS | IIS (res-1): Gene split into 2 ORFs; [NAME] to H. pylori 26695 and J99 ORFs HP1366 and JHP1442, respectively.
CUP1060-CUP1062 | IIS | IIS (mod-1): Contains 15 bp GC tract; Similar to HP1367.
[NAME] | II | II (res-2); Similar to JHP0630.
CUP1439 | II | II ([NAME]); Similar to JHP0629: Cytosine-specific.
CUP1731-CUP1734 | II | Cj1051c homolog: Encodes CjeI.  Coding region fragmented and presumably non-functional.
CUP0798/CUP0799 | III | III (mod-3); Contains 16 bp GC tract; Similar to HP1522 and JHP1411 (both H. pylori ORFs also contain GC tract).
[NAME] | III | III (res-3); Similar to HP1521 and JHP1410.
CUP1577 | III | III (mod-4); CJE0731 homolog.
CUP1578 | III | III (res-4); CJE0732 homolog.
CUP0099 |  | Cj0979c homolog: Putative endonuclease.
CUP0023 |  | Methyltransferase (mod-5); Similar to HH1050 (Helicobacter hepaticus), HP1208, [NAME].
[NAME] |  | Methyltransferase (mod-6); Similar to methylase from Thermoplasma volcanium.
CUP0237 |  | Methyltransferase (mod-7); Similar to HP0481, JHP0433.
[NAME] |  | CJE0310 homolog: Methyltransferase (mod-8).
CUP0945 |  | Methyltransferase (mod-9): Cytosine-specific.
CUP1121 |  | Methyltransferase (mod-10); Similar to HP0263, JHP0248.
CUP1283 |  | Methyltransferase (mod-11): Cytosine-specific; Similar to HP1121, [NAME].
CUP1468 |  | Methyltransferase (mod-12); Similar to HP0054.
CUP1474 |  | Methyltransferase (mod-13); Similar to HP0051, JHP0435: Cytosine-specific.
CUP1477 |  | Methyltransferase (mod-14); Similar to HP0369, JHP1012.
CUP1488 |  | Cj0208 homolog: Methyltransferase (mod-15; Methylates EcoRI restriction sites).
CUP1489 |  | Methyltransferase (mod-16); Similar to HH1050, HP1208, [NAME].
CUP1490 |  | Methyltransferase (mod-17); Similar to methylase from Fusobacterium nucleatum.
CUP1661 |  | Methyltransferase (mod-18); Similar to HH1050, HP1208, [NAME].
CUP1769 |  | Methyltransferase (mod-19); Similar to HP1352, JHP1271.
C. coli RM2228:
Gene(s) | Type | Comment/description
CCO1661-CCO1666 | I | hsdR1/rloIJ/hsdS12/mloA/hsdM1 (Type IAB family).
CCO0070/CUP0071 | IIS | Cj0031/32 homolog: Fused by slipped strand mispairing (G10 - split, G9 - fused).
CCO1119 | II | Cj1051c homolog: Encodes CjeI.
CCO1045 |  | Cj0979c homolog: Putative endonuclease.
CCO1723 |  | Cj0154c homolog: Methyltransferase.
CCO0298 |  | Cj0208 homolog: Methyltransferase (Methylates EcoRI restriction sites).
CCO1115 |  | CJE0310 homolog: Methyltransferase.
CCO1568 |  | Cj1461 homolog: Methyltransferase.