Spreadsheet: 3d7a1876-59ff-488a-96c8-6d5de54614d0
Sheet: Sheet1

Table S3. List of pseudogenes in NoAz involved in processes shown in Figure 6. | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7
Category | Gene symbol | EC number | Gene product | NoAz | Noss | Avar | [NAME]
DNA replication
 | dnaA |  | Chromosomal replication initiator | Aazo_2080 (-) | alr2009 | Ava_0001 | Npun_F0001
 | holB | 2.7.7.7 | DNA polymerase III, delta prime subunit | Aazo_5289 | all4705 | Ava_1963 | Npun_F6434
 | dnaX | 2.7.7.7 | DNA polymerase III, subunits gamma and tau | Aazo_5290 | alr4932 | Ava_2215 | Npun_F4123
 | dnaN | 2.7.7.7 | DNA polymerase III, beta subunit | Aazo_5292 | alr7569 | Ava_C0075 | Npun_R0034
 | ssb |  | Single-stranded DNA-binding protein | Aazo_5287 | alr7579 | Ava_C0119 | Npun_F1842
 | topA | 5.99.1.2 | DNA topoisomerase I | Aazo_3342 | all2631 | Ava_3784 | Npun_F1754
DNA repair
 | recD | 3.1.11.5 | Exodeoxyribonuclease V alpha subunit | [NAME] (-) | all7071 | Ava_B0243 | Npun_AR019
 | xseA | 3.1.11.6 | Exodeoxyribonuclease VII | (-) | all1774 | Ava_0262 | Npun_R2911
 | [NAME] | 3.6.1.- | ATP-dependent DNA helicase [NAME] | Aazo_4326 | alr4842 | Ava_2113 | Npun_F0932
 | recG | 3.6.1.- | ATP-dependent DNA helicase | Aazo_3285 | (-) | (-) | (-)
Photosynthesis
 | psbA |  | Photosystem II, DI subunit | Aazo_3532 | alr4866 | Ava_2138 | Npun_R5455
 | petJ |  | Cytochrome c6 | Aazo_4653 | all0161 | Ava_1529 | Npun_F1886
Respiration
 | ndhD | 1.6.5.3 | NADH dehydrogenase subunit M | Aazo_2878 | alr5050 | Ava_2308 | Npun_R0955
Hydrogenases
 | [NAME] | 1.6.5.3 | NAD-reducing hydrogenase subunit [NAME] | Aazo_4259 (-) | [NAME] | Ava_4654 | (-)
Cell wall/membrane biogenesis
 | rfbD | 1.1.1.133 | dTDP-4-dehydrorhamnose reductase | Aazo_1113 (-) | (-) | (-) | Npun_F0221
 | rfbD | 1.1.1.133 | dTDP-4-dehydrorhamnose reductase | [NAME] (-) | (-) | (-) | Npun_F0221
 | rfbD | 1.1.1.133 | dTDP-4-dehydrorhamnose reductase | Aazo_0585 (-) | alr4490 | Ava_3355 | Npun_F4541
 | dacB | 3.4.16.4 | D-alanyl-D-alanine carboxypeptidase | Aazo_4123 | alr1666 | Ava_0669 | Npun_R1733
 | glf | 5.4.99.9 | UDP-galactopyranose mutase | Aazo_1108 | all5194 | Ava_2434 | Npun_F0220
Galactose metabolism
 | galK | 2.7.1.6 | Galactokinase | Aazo_1125 (-) | (-) | (-) | Npun_F0213
 | galT | 2.7.7.12 | Galactose-1-phosphate uridylyltransferase | Aazo_1122 (-) | (-) | (-) | Npun_F0208
 | [NAME] | 2.7.7.9 | UDP-glucose pyrophosphorylase | Aazo_4168 (-) | all3274 | Ava_4927 | Npun_F1146
Glycolysis
 | pfkA | 2.7.1.11 | 6-phosphofructokinase | Aazo_0224 (-) | alr1913 | Ava_3044 | Npun_R0482
 | ldh | 1.1.1.27 | Lactate dehydrogenase | (-) | (-) | (-) | Npun_R1983
 | gapA | 1.2.1.12 | Glyceraldehyde-3-phosphate dehydrogenase | Aazo_1831 | all2566 | Ava_0495 | Npun_R0031
 | pyk | 2.7.1.40 | Pyruvate kinase | Aazo_1832 | all2564 | Ava_0494 | Npun_R0030
 | gpm | 5.4.2.1 | Phosphoglycerate mutase | Aazo_1610 | alr1107 | Ava_2177 | Npun_F0472
TCA cycle
 | [NAME] | 1.1.1.37 | Malate dehydrogenase | Aazo_3426 (-) | alr4322 | Ava_1273 | Npun_R3934
Pentose phosphate pathway
 | rbsK | 2.7.1.15 | Ribokinase | Aazo_1416 (-) | all1784 | Ava_0252 | Npun_R2732
 | gnl | 3.1.1.17 | Gluconolaconase | Aazo_5311 (-) | (-) | (-) | Npun_F1780
 | gdh | 1.1.1.47 | Glucose 1-dehydrogenase | [NAME] (-) | alr1894 | Ava_3764 | [NAME]
 | talC | 2.2.1.2 | Transaldolase | Aazo_0134 | (-) | (-) | Npun_F5864
Nitrogen metabolism
 | narB | 1.7.7.2 | Nitrate reductase | Aazo_2706 (-) | alr0612 | Ava_4544 | Npun_R1526
 | ureA | 3.5.1.5 | Urease, subunit A | (-) | alr3667 | Ava_3621 | [NAME]
 | ureB | 3.5.1.5 | Urease, subunit B | (-) | alr3668 | Ava_3620 | Npun_F0824
 | ureC | 3.5.1.5 | Urease, subunit C | Aazo_2993 (-) | alr3670 | Ava_3618 | Npun_F0825
 | asnB | 6.3.5.4 | Asparagine synthase (glutamine-hydrolyzing) | [NAME] (-) | (-) | (-) | Npun_R1857
 | asnB | 6.3.5.4 | Asparagine synthase (glutamine-hydrolyzing) | Aazo_3478 (-) | (-) | (-) | Npun_R1853
 | glsA | 3.5.1.2 | Glutaminase | Aazo_0550 (-) | all4774 | Ava_2446 | Npun_F3815
 | glsA | 3.5.1.2 | Glutaminase | Aazo_4285 (-) | all2934 | Ava_0966 | Npun_F6494
Transporters
 | cmpA |  | Bicarbonate transport | Aazo_1532 (-) | alr2877 | Ava_1027 | Npun_R2356
 | cmpB |  | Bicarbonate transport | Aazo_1533 (-) | alr2878 | Ava_1026 | Npun_R2355
 | cmpC | 3.6.3.- | Bicarbonate transport | [NAME] (-) | alr2879 | Ava_1025 | Npun_R2354
 | cmpD | 3.6.3.- | Bicarbonate transport | Aazo_1528 (-) | alr2880 | Ava_1024 | Npun_R2353
 | nrtA/nrtP |  | Nitrate transport | (-) | alr0608 | Ava_4540 | Npun_R1527
 | nrtB |  | Nitrate transport | (-) | alr0609 | Ava_4541 | Npun_R2355
 | nrtC |  | Nitrate transport | (-) | alr0610 | [NAME] | Npun_R2354
 | nrtD | 3.6.3.- | Nitrate transport | (-) | alr0611 | Ava_4543 | Npun_R2353
 | urtA |  | Urea transport | (-) | all1951 | Ava_4361 | Npun_F4615
 | urtB |  | Urea transport | (-) | all1950 | Ava_4362 | Npun_F4616
 | urtC |  | Urea transport | (-) | all1949 | Ava_4363 | Npun_F4617
 | urtD |  | Urea transport | (-) | all1948 | Ava_4364 | Npun_F4618
 | urtE |  | Urea transport | (-) | all1947 | Ava_4365 | Npun_F4623
 | pstS |  | Phosphate transport | Aazo_3360 | alr1094 | Ava_0045 | Npun_R4760
 | pstC |  | Phosphate transport | (-) | (-) | Ava_0046 | Npun_R4759
 | [NAME] |  | Phosphate transport | (-) | (-) | Ava_0047 | [NAME]
 | pstB |  | Phosphate transport | (-) | (-) | Ava_0048 | Npun_R4757
 | pstS |  | Phosphate transport | (-) | all0911 | Ava_4516 | Npun_R4111
 | pstC |  | Phosphate transport | (-) | all0910 | Ava_4515 | Npun_R4110
 | [NAME] |  | Phosphate transport | Aazo_2245 | all0909 | Ava_4514 | Npun_R4109
 | pstB |  | Phosphate transport | Aazo_4692 | all0907 | Ava_4512 | [NAME]
 | feoA |  | Iron transport protein A | Aazo_1341 (-) | asl1429 | Ava_3941 | [NAME]
 | tonB |  | TonB-dependent siderophore receptor | Aazo_4485 (-) | all2236 | Ava_B0148 | Npun_F3454
 | ftr1 |  | Iron permease FTR1 | Aazo_1564 | all3939 | Ava_1763 | Npun_F6213
 | phnD |  | Phosphonate ABC transporter | Aazo_3826 (-) | alr2738 | Ava_4304 | Npun_R5254
 | phnD |  | Phosphonate ABC transporter | Aazo_1571 (-) | all2358 | Ava_0179 | Npun_R5809
 | phnE |  | Phosphonate ABC transporter | Aazo_1575 (-) | [NAME] | Ava_0177 | Npun_R5807
 | phnC |  | Phosphonate ABC transporter | Aazo_1573 (-) | all2357 | Ava_0178 | Npun_R5808
Bold locus tags indicates reverse best hits, (-) = Missing gene or pseudogene without functional copy
NoAz = 'Nostoc azollae' 0708, [NAME] = Nostoc sp. PCC 7120, Avar = Anabaena variabilis ATCC 29413, [NAME] punctiforme PCC 73102