Spreadsheet: 4d5acc79-111a-4dd7-8455-7424655d03f3
Sheet: Supplemental Table 1

Additional File 1.  [NAME] diplotypes involving missense variants and UTR deletion.
 |  |  |  | [NAME] coding SNPs and UTR deletions
 |  |  |  | Exon2 |  | Exon 5 | 3'UTR
 |  |  |  | G75Sa | P102L | A319V | 47-bp indel
 |  |  |  | (rgc) | (cyc) | (gya) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc/-)
 |  |  |  | 14066b | 14148 | 18011 | 20,833 - 20,879
 |  |  |  | 110,550,782c | 110550700 | 110546837 | 110,544,015 - 110,543,969
Breed or species | Region of Prominence | Animal | Diplotype code | 110,640,759d | 110640677 | 110636814 | 110,633,992 - 110,633,946
African White Dorper | South Africa | AWD1 | 1,6/2,3e | G,G (g,g) | P,L (c,t) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
African White Dorper | South Africa | AWD3 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Afrikaner, Namaqua | South Africa | NQA11 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Afrikaner, Ronderib | South Africa | RDA2 | ndf | nd | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Afrikaner, Ronderib | South Africa | RDA4 | 1,3 | G,G (g,g) | P,L (c,t) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Afshari | NW Iran | AFS32 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Afshari | NW Iran | AFS33 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Awassi | Middle east | AW454 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Awassi, Turkish | Turkey | AWT1 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Awassi, Turkish | Turkey | AWT2 | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
[NAME] | Bangladesh | BGE2 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
[NAME] | Bangladesh | BGE4 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Brazilian Creole | Brazil | BCS3 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Brazilian Creole | Brazil | BCS1 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Castellana | Spain | [NAME] | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Castellana | Spain | CAS1 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
[NAME] | Jammu and Kashmir | CHA02 | 1,6/2,3 | G,G (g,g) | P,L (c,t) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
[NAME] | Jammu and Kashmir | CHA05 | 2,6 | G,G (g,g) | P,L (c,t) | A,A (c,c) | (-,-)
[NAME] | England-Scotland | CHVA1 | nd | G,G (g,g) | nd | A,A (c,c) | (-,-)
[NAME] | England-Scotland | CHVC1 | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
Churra | Spain | CHU2 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Churra | Spain | CHU1 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
[NAME] | Turkey | CC50 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Dorset, Poll | USA | PD454 | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
[NAME] | Ethiopia | EMZ1 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Finnsheep | Finland | FIN1 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Finnsheep | Finland | [NAME] | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Garole, Bangledesh | Bangledesh | GAR14 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Garole, Indian | India | GAR4 | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
Garut | Indonesia | GUR4 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Garut | Indonesia | GUR5 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Gulf Coast native | USA Gulf Coast | GCN5 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Gulf Coast native | USA Gulf Coast | GCN4 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Karakas | Turkey | KRS3 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Karakas | Turkey | KRS5 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Karya | Turkey | KR4 | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
Lacaune, Meat | France | [NAME] | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
Lacaune, Milk | France | LAC84 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
[NAME] | Spain | MER454 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
[NAME] | Spain | MERA1 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
[NAME] | Spain | MERC1 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
[NAME] | Brazil | BMN3 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
[NAME] | Brazil | BMN4 | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
Norduz | Eastern Turkey | NDZ1 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Norduz | Eastern Turkey | NDZ4 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Ojalada | Spain | OJA5 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Ojalada | Spain | OJA4 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Ovis canadensis | Alberta | OCAN2 | 3,3 | G,G (g,g) | L,L (t,t) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Ovis canadensis | Alberta | OCAN1 | 3,4 | G,C (g,a) | L,L (t,t) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Ovis canadensis | Canada-USA | OCAN3 | 4,4 | S,S (a,a) | L,L (t,t) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Ovis dalli | Canada-USA | ODAL1 | 3,3 | G,G (g,g) | L,L (t,t) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Ovis dalli | Canada-USA | ODAL2 | 3,3 | G,G (g,g) | L,L (t,t) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Romney | England | ROM454 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
[NAME] | Turkey | SKZ1 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
[NAME] | Turkey | SKZ4 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Salz | Spain | SALA1 | nd | nd | nd | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Salz | Spain | SALA2 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Salz | Spain | SALC1 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Santa Inês | Brazil | BSI3 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Santa Inês | Brazil | BSI4 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Scottish Blackface | United Kingdom | SBF454 | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
Sumatra | Sumatra | SUM2 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Sumatra | Sumatra | SUM7 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Swiss Mirror | Switzerland | SMS2 | 1,1 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
[NAME] | Switzerland | SWAA29 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
[NAME] | Switzerland | SWAN3 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
[NAME] | Switzerland | SWAA27 | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
[NAME] | Switzerland | SWAN4 | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
[NAME] | Netherlands | TEX454 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Tibetan, Eastern | Tibet | ZD11 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Tibetan, Northern | Tibet | ZB08 | 6,6 | G,G (g,g) | L,L (t,t) | A,A (c,c) | (-,-)
[NAME] | Switzerland | VBS2 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
Welsh Hardy Speckled Face | Wales | WHSF1 | 2,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (-,-)
Welsh Mountain, Dolgellau | Wales | DWM1 | 1,5 | G,G (g,g) | P,P (c,c) | A,V (c,t) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc)
Welsh mountain, [NAME] | Wales | TWM1 | 1,2 | G,G (g,g) | P,P (c,c) | A,A (c,c) | (agaggacaagtaaggtccttggccttgcggttcctcggctcttcccc,-)
aThe one-letter amino acid code for the codon is given as provided by the International Union of Pure and Applied Chemistry (IUPAC) and the International Union of Biochemistry and Molecular Biology (IUBMB).  In addition, the lower case one-letter code for nucleotide are shown in parentheses.
bNucleotide positions refer to those in GenBank Accession JX944709.
cNucleotide position in ovine reference genome assembly OARV2.0.
dNucleotide position in ovine reference genome assembly OARV3.1.
eBecause of the loop structure in the Nectin 4 median-joining network (Figure 3B), the haplotype phases of a 1,6 diplotype are ambiguous with those of a 2,3 diplotype and were not resolved in this analysis.
fNot determined because genotypes were missing.