Spreadsheet: a4ac7191-b433-4a62-9c4d-76b72f23b760
Sheet: Sheet1

Supplemental Table S1A
Term | Genes | Count | List Total | Pop Hits | Pop Total | Fold Enrichment | PValue | [NAME] | [NAME] | [NAME]
GO:0042981~regulation of apoptosis | [NAME], TNF, PTGS2, HSPA1B, PTEN, AKT1, IGF1R, KRAS, MAP3K1, [NAME], IFNG, TGM2, [NAME], TOP2A, [NAME], TBX3, BCL2A1, PIM1, TP53, ESR1, IGF1, BIRC5, MAL, ESR2, [NAME], [NAME], IFNB1, JUN | 28 | 72 | 804 | 13528 | 6.54339414040906 | 1.23750312204754e-15 | 2.14084305838468e-12 | 2.14084305838468e-12 | 2.06501482580279e-12
GO:0043067~regulation of programmed cell death | [NAME], TNF, PTGS2, HSPA1B, PTEN, AKT1, IGF1R, KRAS, MAP3K1, [NAME], IFNG, TGM2, [NAME], TOP2A, [NAME], TBX3, BCL2A1, PIM1, TP53, ESR1, IGF1, BIRC5, MAL, ESR2, [NAME], [NAME], IFNB1, JUN | 28 | 72 | 812 | 13528 | 6.47892720306513 | 1.54880927606014e-15 | 2.72470934703505e-12 | 1.36235467351752e-12 | 2.63122856836162e-12
GO:0010941~regulation of cell death | [NAME], TNF, PTGS2, HSPA1B, PTEN, AKT1, IGF1R, KRAS, MAP3K1, [NAME], IFNG, TGM2, [NAME], TOP2A, [NAME], TBX3, BCL2A1, PIM1, TP53, ESR1, IGF1, BIRC5, MAL, ESR2, [NAME], [NAME], IFNB1, JUN | 28 | 72 | 815 | 13528 | 6.45507839127471 | 1.79648849216302e-15 | 3.11395353946863e-12 | 1.03794750572205e-12 | 3.00870439673417e-12
GO:0051173~positive regulation of nitrogen compound metabolic process | [NAME], TNF, FHL2, AKT1, FOS, IGF1R, MAP3K1, IFNG, [NAME], EGFR, HSP90AA1, TBX3, TP53, IGF1, ESR2, STAT3, [NAME], SOD2, RAD51, NCOA1, NCOA2, NCOA3, ETS2, JUN, AREG | 25 | 72 | 644 | 13528 | 7.29382332643202 | 7.70253457699209e-15 | 1.34289246389585e-11 | 3.35720340416401e-12 | 1.29674049276218e-11
[NAME]negative regulation of apoptosis | EGFR, [NAME], TNF, TBX3, BCL2A1, PIM1, TP53, ESR1, IGF1, BIRC5, ESR2, HSPA1B, PTEN, SOD2, AKT1, IGF1R, KRAS, BCL2, TGM2, [NAME] | 20 | 72 | 354 | 13528 | 10.615191462649 | 1.34577915088657e-14 | 2.35492736422315e-11 | 4.7098991373673e-12 | 2.27373675443232e-11
GO:0043069~negative regulation of programmed cell death | EGFR, [NAME], TNF, TBX3, BCL2A1, PIM1, TP53, ESR1, IGF1, BIRC5, ESR2, HSPA1B, PTEN, SOD2, AKT1, IGF1R, KRAS, BCL2, TGM2, [NAME] | 20 | 72 | 359 | 13528 | 10.4673475704116 | 1.73093654256491e-14 | 3.03610470098192e-11 | 5.06017450163653e-12 | 2.93209900803503e-11
GO:0060548~negative regulation of cell death | EGFR, [NAME], TNF, TBX3, BCL2A1, PIM1, TP53, ESR1, IGF1, BIRC5, ESR2, HSPA1B, PTEN, SOD2, AKT1, IGF1R, KRAS, BCL2, TGM2, [NAME] | 20 | 72 | 360 | 13528 | 10.4382716049382 | 1.82554501825355e-14 | 3.19180237795535e-11 | 4.55968596213551e-12 | 3.08197911635943e-11
GO:0031328~positive regulation of cellular biosynthetic process | EGFR, [NAME], HSP90AA1, TNF, TBX3, TP53, FHL2, IGF1, ESR2, [NAME], STAT3, [NAME], AKT1, FOS, IGF1R, NCOA1, NCOA2, NCOA3, JUN, ETS2, MAP3K1, IFNG, IL1B, AREG | 24 | 72 | 685 | 13528 | 6.58296836982968 | 2.94601450982459e-13 | 5.1652704335936e-10 | 6.45659081754956e-11 | 4.9880100050359e-10
GO:0009891~positive regulation of biosynthetic process | EGFR, [NAME], HSP90AA1, TNF, TBX3, TP53, FHL2, IGF1, ESR2, [NAME], STAT3, [NAME], AKT1, FOS, IGF1R, NCOA1, NCOA2, NCOA3, JUN, ETS2, MAP3K1, IFNG, IL1B, AREG | 24 | 72 | 695 | 13528 | 6.48824940047961 | 3.98859923053889e-13 | 6.99277191706926e-10 | 7.76975150884595e-11 | 6.75282052498005e-10
GO:0010604~positive regulation of macromolecule metabolic process | [NAME], TNF, FHL2, AKT1, FOS, IGF1R, MAP3K1, [NAME], IFNG, IL1B, TBX3, TP53, ESR1, IGF1, ESR2, UBE2C, STAT3, BRCA1, RAD51, NCOA1, CCND1, NCOA2, NCOA3, ETS2, JUN, AREG | 26 | 72 | 857 | 13528 | 5.70024633735252 | 4.7755414897207e-13 | 8.37069635828413e-10 | 8.37069302761506e-11 | 8.08353384229576e-10
GO:0051726~regulation of cell cycle | EGFR, TNF, CYP1A1, PTGS2, TBX3, PIM1, TP53, CENPF, IGF1, BIRC5, UBE2C, PTEN, [NAME], AKT1, CCND1, JUN, [NAME], IL1B | 18 | 72 | 331 | 13528 | 10.2175226586102 | 8.39144720020665e-13 | 1.47095380320649e-09 | 1.33723032647026e-10 | 1.4204859510869e-09
GO:0006916~anti-apoptosis | [NAME], TNF, TBX3, BCL2A1, [NAME], IGF1, BIRC5, [NAME], ESR2, [NAME], AKT1, IGF1R, [NAME], TGM2, [NAME] | 15 | 72 | 206 | 13528 | 13.6812297734627 | 2.59780738775951e-12 | 4.55396242937666e-09 | 3.7949687836658e-10 | 4.3977044228427e-09
GO:0042127~regulation of cell proliferation | EGFR, FGFR2, [NAME], FGFR1, TNF, TBX3, PTGS2, TP53, IGF1, ESR2, PTEN, [NAME], [NAME], PGR, IGF1R, CCND1, KRAS, IFNB1, JUN, [NAME], IFNG, TGM2, [NAME], NOS2 | 24 | 72 | 787 | 13528 | 5.72977551884794 | 5.2304256110504e-12 | 9.16884157486919e-09 | 7.05295488678814e-10 | 8.8542395637603e-09
GO:0010033~response to organic substance | EGFR, HSP90AA1, TNF, CYP1B1, CYP1A1, PTGS2, ESR1, FHL2, ESR2, HSPA1B, PTEN, [NAME], STAT3, AKT1, AFP, FOS, IGF1R, CCND1, KRAS, JUN, [NAME], IFNG, IL1B | 23 | 72 | 721 | 13528 | 5.99368161504083 | 7.4059738919394e-12 | 1.29826560613111e-08 | 9.27332544087278e-10 | 1.25371935055795e-08
GO:0007242~intracellular signaling cascade | FGFR1, TNF, FHL2, [NAME], PGR, AKT1, TYMS, IGF1R, KRAS, MAP3K1, IFNG, TGM2, [NAME], NOS2, TOP2A, [NAME], TP53, ESR1, IGF1, ESR2, UBE2C, [NAME], STAT3, NCOA1, CCND1, NCOA2, NCOA3, STMN1, BCAR3 | 29 | 72 | 1256 | 13528 | 4.33819886765746 | 8.46054683120048e-12 | 1.48313713532743e-08 | 9.88758075415319e-10 | 1.43224765380978e-08
GO:0045787~positive regulation of cell cycle | EGFR, AKT1, CCND1, TNF, CYP1A1, TBX3, PIM1, IL1B, IGF1, BIRC5 | 10 | 72 | 57 | 13528 | 32.9629629629629 | 1.31710194439273e-11 | 2.3088797540538e-08 | 1.44304990179477e-09 | 2.22965756968562e-08
GO:0010557~positive regulation of macromolecule biosynthetic process | [NAME], TNF, TBX3, TP53, FHL2, IGF1, ESR2, [NAME], STAT3, AKT1, FOS, IGF1R, NCOA1, NCOA2, NCOA3, JUN, ETS2, MAP3K1, IFNG, IL1B, AREG | 21 | 72 | 654 | 13528 | 6.03312945973496 | 8.06659737484871e-11 | 1.4140734494461e-07 | 8.31807966950037e-09 | 1.36555389218528e-07
GO:0045935~positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | [NAME], TNF, TBX3, TP53, FHL2, IGF1, ESR2, [NAME], STAT3, RAD51, FOS, IGF1R, NCOA1, NCOA2, NCOA3, JUN, ETS2, MAP3K1, IFNG, AREG | 20 | 72 | 624 | 13528 | 6.02207977207977 | 2.86862345318938e-10 | 5.02869506036063e-07 | 2.79372014411194e-08 | 4.85615170298103e-07
GO:0045429~positive regulation of nitric oxide biosynthetic process | EGFR, AKT1, HSP90AA1, TNF, IFNG, IL1B, SOD2 | 7 | 72 | 21 | 13528 | 62.6296296296296 | 8.59077791912143e-10 | 1.50596226566879e-06 | 7.92612284694627e-08 | 1.4542907988968e-06
GO:0042493~response to drug | PTGS2, CYP1A1, TP53, CENPF, PTEN, STAT3, SOD2, FOS, CCND1, BCL2, JUN, IL1B, BCAR3 | 13 | 72 | 216 | 13528 | 11.3081275720164 | 1.13146297552319e-09 | 1.98345253876741e-06 | 9.91727203691894e-08 | 1.91539822891329e-06
GO:0008284~positive regulation of cell proliferation | EGFR, FGFR2, [NAME], FGFR1, TNF, PTGS2, TBX3, IGF1, IGF1R, CCND1, KRAS, JUN, [NAME], IFNG, TGM2, [NAME] | 16 | 72 | 414 | 13528 | 7.2614063338701 | 2.8702562413326e-09 | 5.03154656372739e-06 | 2.39598029527776e-07 | 4.85891631374357e-06
GO:0048545~response to steroid hormone stimulus | FOS, CCND1, TNF, KRAS, PTGS2, BCL2, ESR1, [NAME], ESR2, PTEN, STAT3, BRCA1 | 12 | 72 | 192 | 13528 | 11.7430555555555 | 4.31007934718902e-09 | 7.55554047449091e-06 | 3.43434896410421e-07 | 7.29632217977282e-06
GO:0045428~regulation of nitric oxide biosynthetic process | EGFR, AKT1, HSP90AA1, TNF, IFNG, IL1B, SOD2 | 7 | 72 | 27 | 13528 | 48.7119341563786 | 4.57164658421e-09 | 8.01406442485497e-06 | 3.48438919162141e-07 | 7.73911666973603e-06
GO:0030522~intracellular receptor-mediated signaling pathway | PGR, NCOA1, NCOA2, NCOA3, ESR1, [NAME], NOS2, ESR2, BRCA1 | 9 | 72 | 75 | 13528 | 22.5466666666666 | 4.89521018833394e-09 | 8.58126674752046e-06 | 3.57554251317893e-07 | 8.28686165244008e-06
GO:0009725~response to hormone stimulus | TNF, PTGS2, ESR1, FHL2, ESR2, PTEN, [NAME], STAT3, AKT1, FOS, IGF1R, CCND1, KRAS, [NAME], IL1B | 15 | 72 | 367 | 13528 | 7.67938237965486 | 5.41142398616681e-09 | 9.48618126073164e-06 | 3.79448978238272e-07 | 9.16073457091215e-06
GO:0010628~positive regulation of gene expression | [NAME], TNF, TBX3, TP53, ESR1, FHL2, IGF1, ESR2, [NAME], STAT3, FOS, NCOA1, NCOA2, NCOA3, JUN, ETS2, MAP3K1, IFNG | 18 | 72 | 581 | 13528 | 5.8209982788296 | 5.43799456411903e-09 | 9.53275914050699e-06 | 3.666462626839e-07 | 9.20571470164333e-06
GO:0007346~regulation of mitotic cell cycle | EGFR, CCND1, TNF, CYP1A1, BCL2, TP53, CENPF, IL1B, IGF1, BIRC5, UBE2C | 11 | 72 | 152 | 13528 | 13.5972222222222 | 6.11667526273417e-09 | 1.07224743078893e-05 | 3.97130728302386e-07 | 1.03546198948478e-05
GO:0051054~positive regulation of DNA metabolic process | IGF1R, [NAME], JUN, IFNG, IGF1, AREG, BRCA1, RAD51 | 8 | 72 | 56 | 13528 | 26.8412698412698 | 1.53215032916437e-08 | 2.68582347813239e-05 | 9.59235092468091e-07 | 2.59370203647968e-05
[NAME]~response to endogenous stimulus | TNF, PTGS2, ESR1, FHL2, ESR2, PTEN, [NAME], STAT3, AKT1, FOS, IGF1R, CCND1, KRAS, [NAME], IL1B | 15 | 72 | 405 | 13528 | 6.95884773662551 | 1.88965762176078e-08 | 3.31251497288631e-05 | 1.14226480896206e-06 | 3.19890847699788e-05
GO:0045893~positive regulation of transcription, DNA-dependent | TNF, TBX3, TP53, FHL2, IGF1, ESR2, [NAME], STAT3, FOS, NCOA1, NCOA2, NCOA3, JUN, ETS2, MAP3K1, IFNG | 16 | 72 | 477 | 13528 | 6.30235266713254 | 1.93464636800214e-08 | 3.39137760272389e-05 | 1.13047773142582e-06 | 3.27506770148033e-05
GO:0030518~steroid hormone receptor signaling pathway | PGR, NCOA1, NCOA2, NCOA3, ESR1, [NAME], ESR2, BRCA1 | 8 | 72 | 58 | 13528 | 25.9157088122605 | 1.96996933345483e-08 | 3.45329664553917e-05 | 1.11398527413708e-06 | 3.33486420589501e-05
GO:0051254~positive regulation of RNA metabolic process | TNF, TBX3, TP53, FHL2, IGF1, ESR2, [NAME], STAT3, FOS, NCOA1, NCOA2, NCOA3, JUN, ETS2, MAP3K1, IFNG | 16 | 72 | 481 | 13528 | 6.24994224994225 | 2.16213767797032e-08 | 3.79015556581929e-05 | 1.18444535912587e-06 | 3.66017649633398e-05
GO:0043065~positive regulation of apoptosis | TNF, PTGS2, TP53, MAL, PTEN, [NAME], AKT1, IFNB1, JUN, [NAME], MAP3K1, IFNG, TGM2, [NAME], TOP2A | 15 | 72 | 430 | 13528 | 6.55426356589147 | 4.00564190037677e-08 | 7.02164385528725e-05 | 2.12784330710924e-06 | 6.7809530823748e-05
GO:0043068~positive regulation of programmed cell death | TNF, PTGS2, TP53, MAL, PTEN, [NAME], AKT1, IFNB1, JUN, [NAME], MAP3K1, IFNG, TGM2, [NAME], TOP2A | 15 | 72 | 433 | 13528 | 6.50885296381832 | 4.36865165699702e-08 | 7.65795327621887e-05 | 2.25242290807781e-06 | 7.39547413308727e-05
GO:0010942~positive regulation of cell death | TNF, PTGS2, TP53, MAL, PTEN, [NAME], AKT1, IFNB1, JUN, [NAME], MAP3K1, IFNG, TGM2, [NAME], TOP2A | 15 | 72 | 435 | 13528 | 6.47892720306513 | 4.62696727559634e-08 | 8.11074488376029e-05 | 2.31744697831715e-06 | 7.83276370541763e-05
GO:0012501~programmed cell death | TNF, BCL2A1, TP53, BIRC5, PTEN, [NAME], [NAME], AKT1, KRAS, IFNB1, JUN, [NAME], MAP3K1, IFNG, TGM2, [NAME], TOP2A | 17 | 72 | 611 | 13528 | 5.22767775959265 | 7.79236313900056e-08 | 0.000136590801856906 | 3.79444089082525e-06 | 0.000131913022471952
GO:0007568~aging | FOS, KRAS, TBX3, [NAME], [NAME], TP53, IL1B, PTEN, SOD2 | 9 | 72 | 110 | 13528 | 15.3727272727272 | 1.02788248030683e-07 | 0.000180171575199006 | 4.86992889991988e-06 | 0.000174005055153525
GO:0048660~regulation of smooth muscle cell proliferation | EGFR, TNF, PTGS2, JUN, IFNG, TGM2, IGF1 | 7 | 72 | 46 | 13528 | 28.5917874396135 | 1.33755842934345e-07 | 0.000234446521502951 | 6.17034960503914e-06 | 0.000226428483196539
GO:0051052~regulation of DNA metabolic process | IGF1R, [NAME], JUN, IFNG, TP53, IGF1, AREG, BRCA1, RAD51 | 9 | 72 | 114 | 13528 | 14.8333333333333 | 1.35794621704422e-07 | 0.000238019656755961 | 6.10377593424082e-06 | 0.000229879824531487
GO:0032768~regulation of monooxygenase activity | EGFR, AKT1, TNF, KRAS, IFNG, IL1B | 6 | 72 | 25 | 13528 | 45.0933333333333 | 1.69005769759204e-07 | 0.000296223256566086 | 7.40665105414262e-06 | 0.000286101216206979
GO:0045941~positive regulation of transcription | TNF, TBX3, TP53, FHL2, IGF1, ESR2, [NAME], STAT3, FOS, NCOA1, NCOA2, NCOA3, JUN, ETS2, MAP3K1, IFNG | 16 | 72 | 564 | 13528 | 5.33018124507486 | 1.74579434752558e-07 | 0.000305990951130485 | 7.46430813980403e-06 | 0.000295536575400934
GO:0009991~response to extracellular stimulus | AKT1, FOS, CCND1, PTGS2, CYP1A1, JUN, [NAME], TP53, IL1B, PTEN, SOD2 | 11 | 72 | 220 | 13528 | 9.39444444444444 | 2.0485246413014e-07 | 0.000359041935366399 | 8.55011597977739e-06 | 0.000346784151161738
GO:0014070~response to organic cyclic substance | FOS, CCND1, PTGS2, CYP1A1, JUN, [NAME], [NAME], PTEN, STAT3 | 9 | 72 | 121 | 13528 | 13.9752066115702 | 2.1564478637509e-07 | 0.000377953908670125 | 8.79124859509694e-06 | 0.000365053884454624
GO:0001932~regulation of protein amino acid phosphorylation | EGFR, [NAME], CCND1, TNF, MAP3K1, JUN, [NAME], IFNG, IL1B, IGF1 | 10 | 72 | 173 | 13528 | 10.8606294155427 | 2.80173559638647e-07 | 0.000491023727304473 | 1.1162308585777e-05 | 0.000474291057295239
GO:0031399~regulation of protein modification process | EGFR, [NAME], CCND1, TNF, MAP3K1, JUN, [NAME], IFNG, IL1B, IGF1, UBE2C, BRCA1 | 12 | 72 | 295 | 13528 | 7.64293785310734 | 3.52394566600626e-07 | 0.000617557017284164 | 1.37276343120662e-05 | 0.000596549851628047
[NAME]~apoptosis | TNF, BCL2A1, TP53, BIRC5, PTEN, [NAME], [NAME], AKT1, KRAS, IFNB1, JUN, [NAME], MAP3K1, IFNG, IL1B, TOP2A | 16 | 72 | 602 | 13528 | 4.99372462163159 | 4.03423725853594e-07 | 0.000706951925752097 | 1.5373836910526e-05 | 0.00068293409940523
GO:0009628~response to abiotic stimulus | EGFR, TNF, TP53, [NAME], [NAME], AKT1, FOS, CCND1, KRAS, BCL2, MAP3K1, [NAME], IL1B | 13 | 72 | 368 | 13528 | 6.63737922705314 | 4.14057787195073e-07 | 0.000725580090541799 | 1.54433584347302e-05 | 0.000700935864450524
GO:0043523~regulation of neuron apoptosis | TNF, KRAS, JUN, [NAME], ESR1, TP53, ESR2, SOD2 | 8 | 72 | 90 | 13528 | 16.7012345679012 | 4.2864206759225e-07 | 0.000751127468000989 | 1.56542463372044e-05 | 0.000725624713793227
GO:0032770~positive regulation of monooxygenase activity | AKT1, TNF, KRAS, IFNG, IL1B | 5 | 72 | 13 | 13528 | 72.2649572649572 | 4.80577213288585e-07 | 0.00084209729414908 | 1.7192751330608e-05 | 0.000813542544986223
GO:0048661~positive regulation of smooth muscle cell proliferation | EGFR, TNF, PTGS2, JUN, TGM2, IGF1 | 6 | 72 | 31 | 13528 | 36.3655913978494 | 5.27444380223035e-07 | 0.000924182921942962 | 1.84920338658356e-05 | 0.000892881042613424
GO:0008637~apoptotic mitochondrial changes | AKT1, MAP3K1, JUN, [NAME], TP53, SOD2 | 6 | 72 | 31 | 13528 | 36.3655913978494 | 5.27444380223035e-07 | 0.000924182921942962 | 1.84920338658356e-05 | 0.000892881042613424
GO:0008219~cell death | TNF, BCL2A1, TP53, BIRC5, PTEN, [NAME], [NAME], AKT1, KRAS, IFNB1, JUN, [NAME], MAP3K1, IFNG, TGM2, [NAME], TOP2A | 17 | 72 | 719 | 13528 | 4.44243548137845 | 7.06523538027009e-07 | 0.00123776953024468 | 2.42847286437974e-05 | 0.00119603241068855
GO:0042327~positive regulation of phosphorylation | EGFR, [NAME], CCND1, TNF, BCL2, IFNG, IL1B, IGF1 | 8 | 72 | 97 | 13528 | 15.495990836197 | 7.15906628105035e-07 | 0.00125419760421163 | 2.41340312362448e-05 | 0.00121191640500839
GO:0042325~regulation of phosphorylation | EGFR, [NAME], TNF, PIM1, IGF1, PTEN, AKT1, CCND1, KRAS, BCL2, MAP3K1, JUN, IFNG, IL1B | 14 | 72 | 466 | 13528 | 5.64473056747734 | 7.62804883976486e-07 | 0.00133630382136495 | 2.52298226949276e-05 | 0.00129130723348636
GO:0016265~death | TNF, BCL2A1, TP53, BIRC5, PTEN, [NAME], [NAME], AKT1, KRAS, IFNB1, JUN, [NAME], MAP3K1, IFNG, TGM2, [NAME], TOP2A | 17 | 72 | 724 | 13528 | 4.41175567833026 | 7.74687571863056e-07 | 0.00135710613698425 | 2.51483474696945e-05 | 0.00131142260840766
GO:0006357~regulation of transcription from RNA polymerase II promoter | TNF, TBX3, FST, TP53, FHL2, IGF1, ESR2, [NAME], STAT3, SOD2, FOS, NCOA1, NCOA2, JUN, MAP3K1, NCOR1, ENO1 | 17 | 72 | 727 | 13528 | 4.39355035916246 | 8.18394548456669e-07 | 0.00143361761756299 | 2.60841367213382e-05 | 0.00138541107257417
GO:0031667~response to nutrient levels | AKT1, CCND1, PTGS2, CYP1A1, JUN, [NAME], TP53, IL1B, PTEN, SOD2 | 10 | 72 | 197 | 13528 | 9.5375070501974 | 8.38087140141556e-07 | 0.00146808867423908 | 2.6234787510071e-05 | 0.0014187472580307
GO:0010562~positive regulation of phosphorus metabolic process | EGFR, [NAME], CCND1, TNF, BCL2, IFNG, IL1B, IGF1 | 8 | 72 | 100 | 13528 | 15.0311111111111 | 8.81048247526851e-07 | 0.00154328616564314 | 2.70957426999896e-05 | 0.00149147301982122
GO:0045937~positive regulation of phosphate metabolic process | EGFR, [NAME], CCND1, TNF, BCL2, IFNG, IL1B, IGF1 | 8 | 72 | 100 | 13528 | 15.0311111111111 | 8.81048247526851e-07 | 0.00154328616564314 | 2.70957426999896e-05 | 0.00149147301982122
[NAME]~cell cycle process | EGFR, RAD51C, PIM1, TP53, CENPF, BIRC5, UBE2C, BRCA1, RAD51, AKT1, CCND1, BCL2, IFNG, STMN1, NCOR1 | 15 | 72 | 565 | 13528 | 4.9882005899705 | 1.11764354236028e-06 | 0.00195731218594896 | 3.37792609275133e-05 | 0.00189198724679373
GO:0051174~regulation of phosphorus metabolic process | EGFR, [NAME], TNF, PIM1, IGF1, PTEN, AKT1, CCND1, KRAS, BCL2, MAP3K1, JUN, IFNG, IL1B | 14 | 72 | 485 | 13528 | 5.42359679266895 | 1.19477341708001e-06 | 0.00209224724434875 | 3.54983368912042e-05 | 0.00202255423454866
GO:0019220~regulation of phosphate metabolic process | EGFR, [NAME], TNF, PIM1, IGF1, PTEN, AKT1, CCND1, KRAS, BCL2, MAP3K1, JUN, IFNG, IL1B | 14 | 72 | 485 | 13528 | 5.42359679266895 | 1.19477341708001e-06 | 0.00209224724434875 | 3.54983368912042e-05 | 0.00202255423454866
GO:0043627~response to estrogen stimulus | CCND1, PTGS2, BCL2, ESR1, [NAME], PTEN, STAT3, BRCA1 | 8 | 72 | 105 | 13528 | 14.3153439153439 | 1.22701867198758e-06 | 0.00214865338406411 | 3.5848774944891e-05 | 0.00207713959660127
GO:0007167~enzyme linked receptor protein signaling pathway | EGFR, AKT1, FGFR2, IGF1R, FGFR1, FOS, MAP3K1, JUN, FST, AREG, PTEN, STAT3 | 12 | 72 | 342 | 13528 | 6.59259259259259 | 1.51526528945116e-06 | 0.00265273732239468 | 4.35443316705308e-05 | 0.00256508753982975
GO:0044093~positive regulation of molecular function | EGFR, TNF, PIM1, TP53, UBE2C, AKT1, CCND1, KRAS, NCOA3, IFNB1, BCL2, MAP3K1, IFNG, TGM2, [NAME] | 15 | 72 | 586 | 13528 | 4.80944254835039 | 1.72091476515741e-06 | 0.00301222031241343 | 4.86563352595226e-05 | 0.00291321250606158
GO:0051341~regulation of oxidoreductase activity | EGFR, AKT1, TNF, KRAS, IFNG, IL1B | 6 | 72 | 40 | 13528 | 28.1833333333333 | 1.96917048320083e-06 | 0.00344600809418993 | 5.47915029518453e-05 | 0.00333346011801571
GO:0010564~regulation of cell cycle process | TNF, CYP1A1, CENPF, IL1B, IGF1, BIRC5, UBE2C, BRCA1 | 8 | 72 | 114 | 13528 | 13.1851851851851 | 2.13690690307358e-06 | 0.00373899429157942 | 5.8529565258647e-05 | 0.00361740361340956
GO:0043085~positive regulation of catalytic activity | EGFR, TNF, TP53, PIM1, UBE2C, AKT1, CCND1, KRAS, IFNB1, BCL2, MAP3K1, IFNG, TGM2, [NAME] | 14 | 72 | 520 | 13528 | 5.058547008547 | 2.5906307388765e-06 | 0.00453108508724187 | 6.98649680658247e-05 | 0.00438546158402219
GO:0051384~response to glucocorticoid stimulus | FOS, CCND1, TNF, KRAS, PTGS2, [NAME], IL1B | 7 | 72 | 78 | 13528 | 16.8618233618233 | 3.21440163834475e-06 | 0.00561900910945389 | 8.53729483755172e-05 | 0.0054413640118156
GO:0032270~positive regulation of cellular protein metabolic process | AKT1, [NAME], CCND1, TNF, BCL2, IFNG, IL1B, IGF1, UBE2C, BRCA1 | 10 | 72 | 233 | 13528 | 8.06390081068192 | 3.36463889729718e-06 | 0.00588086154729916 | 8.80292880249822e-05 | 0.00569567999345599
GO:0050792~regulation of viral reproduction | TNF, IFNB1, MAP3K1, [NAME], TOP2A | 5 | 72 | 21 | 13528 | 44.7354497354497 | 3.89710523306137e-06 | 0.00680835619074549 | 0.000100460229788934 | 0.00659701408015633
GO:0051247~positive regulation of protein metabolic process | AKT1, [NAME], CCND1, TNF, BCL2, IFNG, IL1B, IGF1, UBE2C, BRCA1 | 10 | 72 | 243 | 13528 | 7.73205304069501 | 4.74209354679308e-06 | 0.00827845300865315 | 0.000120469695087277 | 0.00802735504938922
GO:0031960~response to corticosteroid stimulus | FOS, CCND1, TNF, KRAS, PTGS2, [NAME], IL1B | 7 | 72 | 85 | 13528 | 15.473202614379 | 5.31768037856687e-06 | 0.00927860410257419 | 0.000133161397365189 | 0.00900165978106049
GO:0010627~regulation of protein kinase cascade | AKT1, [NAME], TNF, MAP3K1, IFNG, TGM2, [NAME], IGF1, NCOR1, PTEN | 10 | 72 | 249 | 13528 | 7.54573850959393 | 5.78180011828471e-06 | 0.0100843335718314 | 0.000142743683095636 | 0.00978727593670125
GO:0031401~positive regulation of protein modification process | [NAME], CCND1, TNF, BCL2, IFNG, IL1B, IGF1, UBE2C, BRCA1 | 9 | 72 | 187 | 13528 | 9.0427807486631 | 5.80432009114977e-06 | 0.0101234124349102 | 0.000141309496112018 | 0.00982539537969229
GO:0032268~regulation of cellular protein metabolic process | EGFR, [NAME], TNF, IGF1, UBE2C, [NAME], AKT1, CCND1, BCL2, MAP3K1, JUN, IFNG, IL1B | 13 | 72 | 474 | 13528 | 5.15307079231129 | 5.820180627976e-06 | 0.0101509342669158 | 0.000139754703702865 | 0.00985224242119331
GO:0033554~cellular response to stress | RAD51C, TNF, TP53, [NAME], SOD2, RAD51, FOS, TYMS, CCND1, BCL2, MAP3K1, JUN, IFNG, TOP2A | 14 | 72 | 566 | 13528 | 4.64742834707499 | 6.54107447335634e-06 | 0.0114010508262553 | 0.000154941252845874 | 0.0110724882151247
GO:0001934~positive regulation of protein amino acid phosphorylation | [NAME], CCND1, TNF, BCL2, IFNG, IL1B, IGF1 | 7 | 72 | 89 | 13528 | 14.7777777777777 | 6.95004724117886e-06 | 0.012109557115669 | 0.000162433141664086 | 0.0117647438255374
GO:0009617~response to bacterium | FOS, TNF, PTGS2, CYP1A1, IFNB1, JUN, IFNG, IL1B, NOS2 | 9 | 72 | 193 | 13528 | 8.76165803108808 | 7.32348382089758e-06 | 0.01275605708856 | 0.000168908287967672 | 0.0123968444859512
GO:0045737~positive regulation of cyclin-dependent protein kinase activity | EGFR, AKT1, CCND1, PIM1 | 4 | 72 | 8 | 13528 | 93.9444444444444 | 7.61357388054322e-06 | 0.0132579742708383 | 0.000173318041297054 | 0.0128878653425368
GO:0010647~positive regulation of cell communication | EGFR, [NAME], TNF, KRAS, PTGS2, NCOA3, IFNG, ESR1, TGM2, [NAME], IGF1 | 11 | 72 | 329 | 13528 | 6.28199932455251 | 7.81978485563486e-06 | 0.0136146078024698 | 0.000175729896786824 | 0.0132369069109183
GO:0022403~cell cycle phase | EGFR, AKT1, RAD51C, CCND1, BCL2, PIM1, CENPF, BIRC5, STMN1, UBE2C, NCOR1, RAD51 | 12 | 72 | 414 | 13528 | 5.44605475040257 | 9.47113946621933e-06 | 0.0164659161736847 | 0.00021014229814098 | 0.0160320194205865
GO:0009314~response to radiation | EGFR, AKT1, FOS, CCND1, KRAS, BCL2, TP53, [NAME], SOD2 | 9 | 72 | 200 | 13528 | 8.455 | 9.50867835950528e-06 | 0.0165306367873625 | 0.000208338199749635 | 0.0160955575716381
GO:0051353~positive regulation of oxidoreductase activity | AKT1, TNF, KRAS, IFNG, IL1B | 5 | 72 | 26 | 13528 | 36.1324786324786 | 9.54362159480935e-06 | 0.0165908784153583 | 0.000206522479794801 | 0.0161547022903829
[NAME]~response to inorganic substance | EGFR, FOS, CCND1, PTGS2, CYP1A1, JUN, [NAME], PTEN, SOD2 | 9 | 72 | 205 | 13528 | 8.24878048780487 | 1.1386791748189e-05 | 0.0197632546272366 | 0.000243399149004286 | 0.0192743948081108
GO:0045740~positive regulation of DNA replication | IGF1R, [NAME], [NAME], IGF1, AREG | 5 | 72 | 28 | 13528 | 33.5515873015873 | 1.29674580374113e-05 | 0.0224756738336593 | 0.000273843236992976 | 0.0219497084905317
GO:0008283~cell proliferation | EGFR, CYP1A1, IFNB1, BCL2, FST, PIM1, TP53, CENPF, IGF1, NOS2, AREG, PTEN | 12 | 72 | 436 | 13528 | 5.17125382262996 | 1.53879389206757e-05 | 0.0266146815768334 | 0.000321082542859896 | 0.0260462969478014
GO:0051329~interphase of mitotic cell cycle | EGFR, AKT1, CCND1, BCL2, PIM1, CENPF, BIRC5 | 7 | 72 | 103 | 13528 | 12.7691477885652 | 1.61425884420611e-05 | 0.0279015425148402 | 0.000332864422959433 | 0.0273234854451853
GO:0008285~negative regulation of cell proliferation | TNF, PTGS2, IFNB1, JUN, [NAME], IFNG, TP53, IL1B, ESR2, PTEN, SOD2 | 11 | 72 | 361 | 13528 | 5.7251461988304 | 1.75383681780693e-05 | 0.0302772072770528 | 0.000357436441877911 | 0.0296856989519755
GO:0006275~regulation of DNA replication | IGF1R, [NAME], [NAME], TP53, IGF1, AREG | 6 | 72 | 62 | 13528 | 18.1827956989247 | 1.770862505327e-05 | 0.0305665929475373 | 0.000356758123553846 | 0.0299738375912794
[NAME]interphase | EGFR, AKT1, CCND1, BCL2, PIM1, CENPF, BIRC5 | 7 | 72 | 106 | 13528 | 12.4077568134171 | 1.90228146729101e-05 | 0.0327974191403311 | 0.000378874928107175 | 0.032197914190768
GO:0007243~protein kinase cascade | EGFR, AKT1, IGF1R, FGFR1, TNF, MAP3K1, IFNG, RPS6KB2, IL1B, NOS2, STAT3 | 11 | 72 | 370 | 13528 | 5.58588588588588 | 2.16792058371626e-05 | 0.0372909675064766 | 0.000426920751064652 | 0.0366933313749484
GO:0007611~learning or memory | FOS, KRAS, PTGS2, JUN, [NAME], ESR2, PTEN | 7 | 72 | 111 | 13528 | 11.8488488488488 | 2.47344039429297e-05 | 0.042433344599845 | 0.000481661145734779 | 0.041863415319554
[NAME]~protein import into nucleus, translocation | AKT1, TNF, JUN, IFNG, TP53 | 5 | 72 | 34 | 13528 | 27.6307189542483 | 2.86817408708478e-05 | 0.0490367044392131 | 0.000552372801396638 | 0.0485428267411713
GO:0007610~behavior | FOS, KRAS, PTGS2, CXCL3, JUN, [NAME], IFNG, IL1B, ESR2, PTEN, STAT3, SOD2 | 12 | 72 | 469 | 13528 | 4.80739161336176 | 3.022059789675e-05 | 0.0515986569053713 | 0.000575676719568041 | 0.0511466607355015
GO:0019932~second-messenger-mediated signaling | EGFR, IGF1R, TYMS, TNF, TGM2, IGF1, NOS2, UBE2C, TOP2A | 9 | 72 | 235 | 13528 | 7.19574468085106 | 3.05124705851112e-05 | 0.0520837997389564 | 0.000574987072222366 | 0.0516405187965807
GO:0031331~positive regulation of cellular catabolic process | AKT1, TNF, IFNG, IL1B, IGF1 | 5 | 72 | 36 | 13528 | 26.0956790123456 | 3.61431766431942e-05 | 0.061394610598645 | 0.00067381685871859 | 0.0611674067861556
GO:0007049~cell cycle | EGFR, RAD51C, PIM1, TP53, CENPF, BIRC5, UBE2C, BRCA1, RAD51, AKT1, CCND1, BCL2, IFNG, STMN1, NCOR1 | 15 | 72 | 776 | 13528 | 3.63187285223367 | 4.2057394710774e-05 | 0.0710758248375507 | 0.000775784853165206 | 0.0711730636063556
GO:0040012~regulation of locomotion | EGFR, AKT1, IGF1R, [NAME], MAP3K1, [NAME], IGF1, PTEN | 8 | 72 | 192 | 13528 | 7.8287037037037 | 6.42088646161293e-05 | 0.106457833899523 | 0.00117183113406305 | 0.108640479615351
GO:0003006~reproductive developmental process | PGR, AKT1, IGF1R, AFP, CCND1, PTGS2, TBX3, [NAME], FST | 9 | 72 | 262 | 13528 | 6.45419847328244 | 6.5919779683867e-05 | 0.109133935031773 | 0.0011906430205526 | 0.111533803822083
GO:0051051~negative regulation of transport | AKT1, TNF, PTGS2, BCL2, FST, IL1B, PTEN | 7 | 72 | 135 | 13528 | 9.74238683127572 | 7.43403827087084e-05 | 0.122188617819369 | 0.00132894815607276 | 0.125772715557614
GO:0070141~response to UV-A | EGFR, AKT1, CCND1 | 3 | 72 | 3 | 13528 | 187.888888888888 | 8.12013160357864e-05 | 0.132683820688031 | 0.00143686254796648 | 0.137372874580155
GO:0060559~positive regulation of calcidiol 1-monooxygenase activity | TNF, IFNG, IL1B | 3 | 72 | 3 | 13528 | 187.888888888888 | 8.12013160357864e-05 | 0.132683820688031 | 0.00143686254796648 | 0.137372874580155
GO:0009416~response to light stimulus | EGFR, AKT1, FOS, CCND1, KRAS, BCL2, TP53 | 7 | 72 | 138 | 13528 | 9.5305958132045 | 8.39875047597682e-05 | 0.13690997666869 | 0.0014712793950331 | 0.142083275829474
GO:0007005~mitochondrion organization | AKT1, HSP90AA1, MAP3K1, JUN, [NAME], TP53, SOD2 | 7 | 72 | 138 | 13528 | 9.5305958132045 | 8.39875047597682e-05 | 0.13690997666869 | 0.0014712793950331 | 0.142083275829474
GO:0009611~response to wounding | AKT1, FOS, TNF, CYP1A1, MAP3K1, [NAME], BCL2, [NAME], IGF1, TFPI2, STAT3, SOD2 | 12 | 72 | 530 | 13528 | 4.25408805031446 | 9.13145860060281e-05 | 0.147925895038119 | 0.00158371270318713 | 0.154469627253706
GO:0048015~phosphoinositide-mediated signaling | IGF1R, TYMS, TGM2, IGF1, UBE2C, TOP2A | 6 | 72 | 88 | 13528 | 12.810606060606 | 9.64711546223464e-05 | 0.155594198004508 | 0.00165668590274348 | 0.163185883884331
GO:0009896~positive regulation of catabolic process | AKT1, TNF, IFNG, IL1B, IGF1 | 5 | 72 | 49 | 13528 | 19.172335600907 | 0.000123488693780049 | 0.194658644581332 | 0.00209962810278974 | 0.208842498288874
GO:0045944~positive regulation of transcription from RNA polymerase II promoter | FOS, NCOA1, TNF, NCOA2, MAP3K1, JUN, TP53, IGF1, ESR2, STAT3 | 10 | 72 | 371 | 13528 | 5.06439053608864 | 0.000132199860070733 | 0.20686487486874 | 0.00222599642631138 | 0.223559204543444
GO:0016481~negative regulation of transcription | TNF, NCOA2, TBX3, IFNB1, FST, TP53, CENPF, NCOR1, STAT3, [NAME], ENO1 | 11 | 72 | 459 | 13528 | 4.50278382958121 | 0.000132396586587652 | 0.207138385725106 | 0.002208097431452 | 0.223891532138587
GO:0051385~response to mineralocorticoid stimulus | FOS, CCND1, KRAS, BCL2 | 4 | 72 | 20 | 13528 | 37.5777777777777 | 0.000148134753042146 | 0.228716645841945 | 0.0024469960970862 | 0.250474441697978
GO:0009967~positive regulation of signal transduction | [NAME], TNF, KRAS, NCOA3, IFNG, ESR1, TGM2, [NAME], IGF1 | 9 | 72 | 295 | 13528 | 5.7322033898305 | 0.000150264600687505 | 0.231591386025043 | 0.00245896838766823 | 0.254071397530308
GO:0031659~positive regulation of cyclin-dependent protein kinase activity during G1/S | EGFR, AKT1, PIM1 | 3 | 72 | 4 | 13528 | 140.916666666666 | 0.000161850528866657 | 0.247042836075488 | 0.00262383818507616 | 0.273635951515494
GO:0031657~regulation of cyclin-dependent protein kinase activity during G1/S | EGFR, AKT1, PIM1 | 3 | 72 | 4 | 13528 | 140.916666666666 | 0.000161850528866657 | 0.247042836075488 | 0.00262383818507616 | 0.273635951515494
GO:0045860~positive regulation of protein kinase activity | EGFR, AKT1, CCND1, TNF, KRAS, MAP3K1, PIM1, IL1B | 8 | 72 | 223 | 13528 | 6.74040857000498 | 0.000163518783589075 | 0.249241962629631 | 0.00262656165776675 | 0.276452749042399
GO:0006468~protein amino acid phosphorylation | FGFR2, EGFR, FGFR1, TNF, PIM1, RPS6KB2, AKT1, IGF1R, CCND1, BCL2, MAP3K1, IFNG, IL1B | 13 | 72 | 667 | 13528 | 3.66200233216724 | 0.000164747300951009 | 0.250857313439249 | 0.00262224508279229 | 0.27852701550336
GO:0007169~[NAME] receptor [NAME] signaling pathway | EGFR, AKT1, FGFR2, IGF1R, FGFR1, AREG, PTEN, STAT3 | 8 | 72 | 224 | 13528 | 6.71031746031746 | 0.000168095627137877 | 0.255242341150033 | 0.00265140136541575 | 0.28418022621357
GO:0045884~regulation of survival gene product expression | AKT1, [NAME], [NAME], ESR2 | 4 | 72 | 21 | 13528 | 35.7883597883597 | 0.000172174361007552 | 0.260549281575911 | 0.00269143978546781 | 0.291066227343961
GO:0001836~release of cytochrome c from mitochondria | JUN, [NAME], TP53, SOD2 | 4 | 72 | 21 | 13528 | 35.7883597883597 | 0.000172174361007552 | 0.260549281575911 | 0.00269143978546781 | 0.291066227343961
GO:0006928~cell motion | NRCAM, TNF, PTGS2, [NAME], CXCL3, IFNG, IL1B, IGF1, ESR2, PTEN, STAT3 | 11 | 72 | 475 | 13528 | 4.35111111111111 | 0.000175074588352255 | 0.264299830916239 | 0.00271253231359946 | 0.295962319910858
[NAME]~regulation of cyclin-dependent protein kinase activity | EGFR, AKT1, CCND1, PIM1, PTEN | 5 | 72 | 54 | 13528 | 17.3971193415637 | 0.000180716613921056 | 0.271541668626803 | 0.00277530707066664 | 0.305486400811949
GO:0080135~regulation of cellular response to stress | AKT1, TNF, MAP3K1, IL1B, NCOR1, BRCA1 | 6 | 72 | 103 | 13528 | 10.9449838187702 | 0.00020285481970212 | 0.299275564941514 | 0.00308774977662651 | 0.342848764441905
GO:0033674~positive regulation of kinase activity | EGFR, AKT1, CCND1, TNF, KRAS, MAP3K1, PIM1, IL1B | 8 | 72 | 231 | 13528 | 6.5069745069745 | 0.000203126287336518 | 0.299609015961126 | 0.00306526272916851 | 0.343306835077672
GO:0006355~regulation of transcription, DNA-dependent | TNF, TBX3, FST, TP53, ESR1, FHL2, IGF1, ESR2, [NAME], STAT3, [NAME], PGR, FOS, NCOA1, NCOA2, NCOA3, JUN, ETS2, MAP3K1, IFNG, NCOR1, ENO1 | 22 | 72 | 1773 | 13528 | 2.33139061227047 | 0.00020499986233027 | 0.301906058474376 | 0.00306709535811511 | 0.34646822492792
GO:0000082~G1/S transition of mitotic cell cycle | EGFR, AKT1, CCND1, BCL2, PIM1 | 5 | 72 | 56 | 13528 | 16.7757936507936 | 0.000208230789213005 | 0.305849569876657 | 0.00308900378893628 | 0.35191973029498
GO:0051789~response to protein stimulus | FOS, CCND1, HSP90AA1, BCL2, IFNG, [NAME] | 6 | 72 | 107 | 13528 | 10.5358255451713 | 0.00024238363357149 | 0.346197533537225 | 0.00356464003784462 | 0.40952826990992
GO:0030334~regulation of cell migration | EGFR, AKT1, IGF1R, MAP3K1, [NAME], IGF1, PTEN | 7 | 72 | 169 | 13528 | 7.78238001314924 | 0.000254553757110126 | 0.360001560532848 | 0.00371217229731468 | 0.430049089771822
GO:0009411~response to UV | EGFR, AKT1, CCND1, BCL2, TP53 | 5 | 72 | 59 | 13528 | 15.9227871939736 | 0.000254990186249538 | 0.360491135347935 | 0.00368785085039724 | 0.430784906819381
GO:0001501~skeletal system development | EGFR, FGFR1, PTGS2, TBX3, [NAME], [NAME], [NAME], IGF1, MMP2 | 9 | 72 | 319 | 13528 | 5.30094043887147 | 0.000256097212973874 | 0.361731290855223 | 0.00367353036219419 | 0.432651324633526
GO:0051347~positive regulation of transferase activity | EGFR, AKT1, CCND1, TNF, KRAS, MAP3K1, PIM1, IL1B | 8 | 72 | 240 | 13528 | 6.26296296296296 | 0.000256611900808958 | 0.362307055197461 | 0.00365102920708026 | 0.43351906351694
GO:0010212~response to ionizing radiation | CCND1, BCL2, TP53, [NAME], SOD2 | 5 | 72 | 60 | 13528 | 15.6574074074074 | 0.00027212748705532 | 0.379422265112581 | 0.00384022357347457 | 0.459674253890285
GO:0051252~regulation of RNA metabolic process | TNF, TBX3, FST, TP53, ESR1, FHL2, IGF1, ESR2, [NAME], STAT3, [NAME], PGR, FOS, NCOA1, NCOA2, NCOA3, JUN, ETS2, MAP3K1, IFNG, NCOR1, ENO1 | 22 | 72 | 1813 | 13528 | 2.27995342281056 | 0.000280312336372674 | 0.388265191318171 | 0.0039239324545558 | 0.473469148452676
[NAME]negative regulation of gene expression | TNF, NCOA2, TBX3, IFNB1, FST, TP53, CENPF, NCOR1, STAT3, [NAME], ENO1 | 11 | 72 | 504 | 13528 | 4.10074955908289 | 0.000282200153166477 | 0.390286853100401 | 0.00391902022689905 | 0.476650654056132
GO:0051240~positive regulation of multicellular organismal process | EGFR, AKT1, TNF, PTGS2, BCL2, FST, IFNG, IL1B | 8 | 72 | 244 | 13528 | 6.16029143897996 | 0.000283769245437648 | 0.391962110533586 | 0.00390980194611123 | 0.479294945807329
GO:0031329~regulation of cellular catabolic process | AKT1, TNF, IFNG, IL1B, IGF1 | 5 | 72 | 61 | 13528 | 15.4007285974499 | 0.000290077010132717 | 0.398650369594266 | 0.00396538860832573 | 0.489924354819892
GO:0001568~blood vessel development | AKT1, TBX3, [NAME], TGM2, [NAME], NOS2, PTEN, MMP2 | 8 | 72 | 245 | 13528 | 6.13514739229024 | 0.000290907924772665 | 0.39952590800604 | 0.00394595991447577 | 0.491324475101995
GO:0045862~positive regulation of proteolysis | AKT1, TNF, IFNG, IL1B | 4 | 72 | 25 | 13528 | 30.0622222222222 | 0.00029329648917632 | 0.402035660219185 | 0.00394775749217901 | 0.49534918658517
GO:0045934~negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | TNF, NCOA2, TBX3, IFNB1, FST, TP53, CENPF, NCOR1, STAT3, [NAME], ENO1 | 11 | 72 | 512 | 13528 | 4.03667534722222 | 0.000319960102946299 | 0.429350338879257 | 0.00427313270842777 | 0.540266760713592
GO:0006952~defense response | AKT1, FOS, TNF, IFNB1, CXCL3, BCL2, IFNG, IL1B, HP, NOS2, ESR2, STAT3 | 12 | 72 | 615 | 13528 | 3.66612466124661 | 0.000334258339400622 | 0.443480362260806 | 0.00442995278213409 | 0.564345737662763
GO:0001944~vasculature development | AKT1, TBX3, [NAME], TGM2, [NAME], NOS2, PTEN, MMP2 | 8 | 72 | 251 | 13528 | 5.98849048251438 | 0.000336838691387952 | 0.445992855604386 | 0.00443058965670428 | 0.568690600873222
GO:0001503~ossification | EGFR, PTGS2, [NAME], [NAME], IGF1, MMP2 | 6 | 72 | 115 | 13528 | 9.80289855072463 | 0.000338771181578209 | 0.44786709753767 | 0.00442277638431276 | 0.571944460694884
[NAME]~negative regulation of nitrogen compound metabolic process | TNF, NCOA2, TBX3, IFNB1, FST, TP53, CENPF, NCOR1, STAT3, [NAME], ENO1 | 11 | 72 | 519 | 13528 | 3.98223078569899 | 0.000356392743726495 | 0.464667824273055 | 0.00461795493892547 | 0.601610412794029
GO:0045732~positive regulation of protein catabolic process | AKT1, TNF, IFNG, IL1B | 4 | 72 | 27 | 13528 | 27.835390946502 | 0.000370201313997448 | 0.477475317253201 | 0.00476129844357775 | 0.624851361324396
GO:0046328~regulation of JNK cascade | AKT1, TNF, MAP3K1, IL1B, NCOR1 | 5 | 72 | 65 | 13528 | 14.4529914529914 | 0.000370444761640416 | 0.477698346828728 | 0.00472972818874262 | 0.625261057666393
GO:0046883~regulation of hormone secretion | TNF, FST, IFNG, IL1B, NOS2 | 5 | 72 | 66 | 13528 | 14.2340067340067 | 0.000392791987416509 | 0.497771267505163 | 0.00497814472193203 | 0.662862280113441
GO:0033273~response to vitamin | CCND1, PTGS2, CYP1A1, [NAME], IL1B | 5 | 72 | 66 | 13528 | 14.2340067340067 | 0.000392791987416509 | 0.497771267505163 | 0.00497814472193203 | 0.662862280113441
GO:0010605~negative regulation of macromolecule metabolic process | TNF, TBX3, FST, TP53, CENPF, UBE2C, STAT3, BRCA1, NCOA2, IFNB1, JUN, NCOR1, ENO1 | 13 | 72 | 734 | 13528 | 3.3277323645171 | 0.000397185551277592 | 0.501626050665455 | 0.00499757526073418 | 0.670253272605492
GO:0040008~regulation of growth | NRCAM, AKT1, BCL2, IFNG, TP53, IGF1, ESR2, STAT3, ENO1 | 9 | 72 | 341 | 13528 | 4.95894428152492 | 0.000400748958247452 | 0.504730751083261 | 0.00500638128262986 | 0.676247368825266
GO:0045833~negative regulation of lipid metabolic process | AKT1, TNF, IL1B, BRCA1 | 4 | 72 | 28 | 13528 | 26.8412698412698 | 0.000413069376714657 | 0.515317001236608 | 0.00512342749527516 | 0.696969231106014
GO:0045859~regulation of protein kinase activity | EGFR, AKT1, CCND1, TNF, KRAS, MAP3K1, PIM1, IL1B, PTEN | 9 | 72 | 345 | 13528 | 4.90144927536231 | 0.000433096497711042 | 0.532044753762878 | 0.00533349105774749 | 0.730644410313419
GO:0045449~regulation of transcription | TNF, FST, FHL2, PGR, FOS, KRAS, MAP3K1, IFNG, IL1B, ENO1, TBX3, PIM1, ESR1, TP53, IGF1, CENPF, ESR2, STAT3, [NAME], [NAME], NCOA1, NCOA2, NCOA3, IFNB1, ETS2, JUN, NCOR1 | 27 | 72 | 2601 | 13528 | 1.95040369088812 | 0.000446213821758991 | 0.542687081204788 | 0.00545630057197632 | 0.752695088432719
GO:0018105~peptidyl-serine phosphorylation | AKT1, MAP3K1, [NAME], IFNG | 4 | 72 | 29 | 13528 | 25.9157088122605 | 0.000459002444838474 | 0.552829804462426 | 0.00557341063884409 | 0.774188771737538
GO:0060348~bone development | EGFR, PTGS2, [NAME], [NAME], IGF1, MMP2 | 6 | 72 | 123 | 13528 | 9.16531165311653 | 0.000461743808489525 | 0.554974560068973 | 0.00556805322886677 | 0.77879557819751
GO:0046545~development of primary female sexual characteristics | PGR, AFP, TBX3, [NAME], FST | 5 | 72 | 69 | 13528 | 13.6151368760064 | 0.000465611284255146 | 0.557982878013542 | 0.00557622127844104 | 0.785294451177376
GO:0070302~regulation of stress-activated protein kinase signaling pathway | AKT1, TNF, MAP3K1, IL1B, NCOR1 | 5 | 72 | 69 | 13528 | 13.6151368760064 | 0.000465611284255146 | 0.557982878013542 | 0.00557622127844104 | 0.785294451177376
GO:0046660~female sex differentiation | PGR, AFP, TBX3, [NAME], FST | 5 | 72 | 69 | 13528 | 13.6151368760064 | 0.000465611284255146 | 0.557982878013542 | 0.00557622127844104 | 0.785294451177376
GO:0042592~homeostatic process | ALDOA, TP53, IGF1, HP, MAL, STAT3, [NAME], AKT1, BCL2, JUN, IFNG, TGM2, [NAME] | 13 | 72 | 751 | 13528 | 3.252404201805 | 0.000488164430534767 | 0.575125389893657 | 0.00580594520599342 | 0.823184586746383
GO:0019221~cytokine-mediated signaling pathway | TNF, KRAS, TGM2, [NAME], STAT3 | 5 | 72 | 70 | 13528 | 13.4206349206349 | 0.000491886972570525 | 0.577890282266216 | 0.00581068743481028 | 0.829437288354217
GO:0051270~regulation of cell motion | EGFR, AKT1, IGF1R, MAP3K1, [NAME], IGF1, PTEN | 7 | 72 | 193 | 13528 | 6.8146229130685 | 0.000517469378676733 | 0.596411145549563 | 0.00607115070662778 | 0.872397664316604
GO:0032535~regulation of cellular component size | AKT1, FGFR2, FGFR1, MAP3K1, [NAME], TP53, ESR2, ENO1 | 8 | 72 | 271 | 13528 | 5.54653546535465 | 0.00053364272227069 | 0.607698807448131 | 0.00621875225788093 | 0.899548424597385
GO:0045137~development of primary sexual characteristics | PGR, AFP, CCND1, TBX3, [NAME], FST | 6 | 72 | 127 | 13528 | 8.8766404199475 | 0.000534571355818405 | 0.608337253640558 | 0.00618841576870243 | 0.901107141933899
GO:0010558~negative regulation of macromolecule biosynthetic process | TNF, NCOA2, TBX3, IFNB1, FST, TP53, CENPF, NCOR1, STAT3, [NAME], ENO1 | 11 | 72 | 547 | 13528 | 3.77838716229941 | 0.000538785545297695 | 0.611221533093916 | 0.00619615568443399 | 0.908180395999724
GO:0043549~regulation of kinase activity | EGFR, AKT1, CCND1, TNF, KRAS, MAP3K1, PIM1, IL1B, PTEN | 9 | 72 | 357 | 13528 | 4.73669467787114 | 0.000543131662873771 | 0.614173872993138 | 0.00620529757408727 | 0.9154745855661
GO:0045080~positive regulation of chemokine biosynthetic process | TNF, IFNG, IL1B | 3 | 72 | 7 | 13528 | 80.5238095238095 | 0.00056072336272602 | 0.625896858018132 | 0.00636423167397159 | 0.944993981204311
GO:0060558~regulation of calcidiol 1-monooxygenase activity | TNF, IFNG, IL1B | 3 | 72 | 7 | 13528 | 80.5238095238095 | 0.00056072336272602 | 0.625896858018132 | 0.00636423167397159 | 0.944993981204311
GO:0010038~response to metal ion | EGFR, CCND1, PTGS2, CYP1A1, BCL2, PTEN | 6 | 72 | 129 | 13528 | 8.73901808785529 | 0.000574070632277924 | 0.634553280891071 | 0.00647337481929766 | 0.967385575323453
GO:0006970~response to osmotic stress | EGFR, TNF, MAP3K1, TP53 | 4 | 72 | 32 | 13528 | 23.4861111111111 | 0.000616072974707222 | 0.660509302636061 | 0.00690113303725359 | 1.0378183088306
GO:0051094~positive regulation of developmental process | NRCAM, AKT1, [NAME], TNF, JUN, [NAME], FST, IL1B | 8 | 72 | 278 | 13528 | 5.40687450039968 | 0.000620947363096744 | 0.663399605265023 | 0.00691141209614643 | 1.04598900231146
[NAME] regulation of cellular biosynthetic process | TNF, NCOA2, TBX3, IFNB1, FST, TP53, CENPF, NCOR1, STAT3, [NAME], ENO1 | 11 | 72 | 561 | 13528 | 3.68409586056644 | 0.000655742207848343 | 0.683329395640002 | 0.00725138564510929 | 1.10429542551615
GO:0007569~cell aging | KRAS, TBX3, [NAME], TP53 | 4 | 72 | 33 | 13528 | 22.7744107744107 | 0.00067513949158556 | 0.693923200281753 | 0.00741837986189808 | 1.13678580984609
GO:0032583~regulation of gene-specific transcription | TNF, MAP3K1, TP53, IGF1, ESR2, NCOR1 | 6 | 72 | 134 | 13528 | 8.41293532338308 | 0.000682410135759368 | 0.697802144494532 | 0.00745130860491705 | 1.14896152606869
GO:0000278~mitotic cell cycle | EGFR, AKT1, CCND1, BCL2, PIM1, CENPF, BIRC5, STMN1, UBE2C | 9 | 72 | 370 | 13528 | 4.57027027027027 | 0.000686921911019745 | 0.700184467857025 | 0.00745399250583467 | 1.1565164188278
GO:0048732~gland development | EGFR, PGR, IGF1R, TBX3, [NAME], IGF1 | 6 | 72 | 135 | 13528 | 8.35061728395061 | 0.000705797433979091 | 0.709949355723489 | 0.00761101028100585 | 1.18811727804711
GO:0032496~response to lipopolysaccharide | FOS, PTGS2, CYP1A1, JUN, IL1B | 5 | 72 | 77 | 13528 | 12.2005772005772 | 0.000706238635350355 | 0.71017376007642 | 0.00756920638796854 | 1.1888558110204
GO:0051338~regulation of transferase activity | EGFR, AKT1, CCND1, TNF, KRAS, MAP3K1, PIM1, IL1B, PTEN | 9 | 72 | 372 | 13528 | 4.54569892473118 | 0.000711547906899605 | 0.712860599104507 | 0.00757958907971456 | 1.19774266554766
GO:0008361~regulation of cell size | AKT1, FGFR2, FGFR1, BCL2, TP53, ESR2, ENO1 | 7 | 72 | 206 | 13528 | 6.38457389428263 | 0.000729023397762383 | 0.721529759234305 | 0.00771820643624332 | 1.22698847540796
GO:0009890~negative regulation of biosynthetic process | TNF, NCOA2, TBX3, IFNB1, FST, TP53, CENPF, NCOR1, STAT3, [NAME], ENO1 | 11 | 72 | 573 | 13528 | 3.60694202055458 | 0.000772083467917348 | 0.7417907771184 | 0.0081233623464082 | 1.29901616297748
GO:0034097~response to cytokine stimulus | FOS, PTGS2, JUN, BCL2, STAT3 | 5 | 72 | 79 | 13528 | 11.8917018284106 | 0.000777963229064969 | 0.744440570887495 | 0.00813618348185118 | 1.30884755494862
GO:0007584~response to nutrient | CCND1, PTGS2, CYP1A1, [NAME], [NAME], PTEN | 6 | 72 | 140 | 13528 | 8.05238095238095 | 0.000831857381592235 | 0.767497163225575 | 0.00864605395921802 | 1.39891961080054
GO:0007059~chromosome segregation | RAD51C, CENPF, BIRC5, TOP2A, BRCA1 | 5 | 72 | 81 | 13528 | 11.5980795610425 | 0.000854691656635183 | 0.776627639157336 | 0.0088301038453944 | 1.43705867530919
GO:0016310~phosphorylation | FGFR2, EGFR, FGFR1, TNF, PIM1, RPS6KB2, AKT1, IGF1R, CCND1, BCL2, MAP3K1, IFNG, IL1B | 13 | 72 | 800 | 13528 | 3.05319444444444 | 0.000854887597452817 | 0.776704416487694 | 0.00878039518303575 | 1.43738588638566
GO:0030521~androgen receptor signaling pathway | NCOA1, NCOA3, FHL2, [NAME] | 4 | 72 | 36 | 13528 | 20.8765432098765 | 0.000873625613346776 | 0.7839261548218 | 0.00891983423676046 | 1.46867268592477
GO:0051044~positive regulation of membrane protein ectodomain proteolysis | TNF, IFNG, IL1B | 3 | 72 | 9 | 13528 | 62.6296296296296 | 0.000954726421968149 | 0.812585934986285 | 0.00968785382876413 | 1.60397870442637
GO:0046777~protein amino acid autophosphorylation | EGFR, AKT1, IGF1R, MAP3K1, PIM1 | 5 | 72 | 85 | 13528 | 11.0522875816993 | 0.00102391710853797 | 0.834013073058933 | 0.0103269215181223 | 1.71927603022709
GO:0006606~protein import into nucleus | AKT1, TNF, JUN, IFNG, TP53 | 5 | 72 | 86 | 13528 | 10.9237726098191 | 0.0010696467700222 | 0.846812764747049 | 0.0107242323698246 | 1.7954088076917
GO:0002237~response to molecule of bacterial origin | FOS, PTGS2, CYP1A1, JUN, IL1B | 5 | 72 | 86 | 13528 | 10.9237726098191 | 0.0010696467700222 | 0.846812764747049 | 0.0107242323698246 | 1.7954088076917
GO:0018209~peptidyl-serine modification | AKT1, MAP3K1, [NAME], IFNG | 4 | 72 | 39 | 13528 | 19.2706552706552 | 0.00110569873348457 | 0.856204374184173 | 0.0110208900860737 | 1.85539059950782
GO:0043193~positive regulation of gene-specific transcription | TNF, MAP3K1, TP53, IGF1, ESR2 | 5 | 72 | 87 | 13528 | 10.7982120051085 | 0.00111679313838085 | 0.858977013993629 | 0.0110680231333798 | 1.87384208213332
GO:0044057~regulation of system process | EGFR, TNF, KRAS, PTGS2, FST, IFNG, IL1B, NOS2 | 8 | 72 | 309 | 13528 | 4.86443725278676 | 0.00115366056402551 | 0.867812568670413 | 0.0113672963694068 | 1.93513411091542
GO:0051170~nuclear import | AKT1, TNF, JUN, IFNG, TP53 | 5 | 72 | 88 | 13528 | 10.675505050505 | 0.00116537989946415 | 0.870503609794157 | 0.0114180343967615 | 1.95460993832023
GO:0007548~sex differentiation | PGR, AFP, CCND1, TBX3, [NAME], FST | 6 | 72 | 151 | 13528 | 7.46578366445916 | 0.00116762243780261 | 0.871012274958665 | 0.0113763476128669 | 1.95833629532243
GO:0048524~positive regulation of viral reproduction | IFNB1, MAP3K1, TOP2A | 3 | 72 | 10 | 13528 | 56.3666666666666 | 0.00118935999636484 | 0.875840585038232 | 0.0115230339105552 | 1.99445002226729
GO:0045073~regulation of chemokine biosynthetic process | TNF, IFNG, IL1B | 3 | 72 | 10 | 13528 | 56.3666666666666 | 0.00118935999636484 | 0.875840585038232 | 0.0115230339105552 | 1.99445002226729
GO:0050796~regulation of insulin secretion | TNF, IFNG, IL1B, NOS2 | 4 | 72 | 40 | 13528 | 18.7888888888888 | 0.00119087471946217 | 0.876170221192214 | 0.0114742562017603 | 1.99696604331414
GO:0051098~regulation of binding | TNF, KRAS, NCOA3, BCL2, PIM1, IL1B | 6 | 72 | 153 | 13528 | 7.36819172113289 | 0.00123808722644504 | 0.886017638896089 | 0.0118615714223089 | 2.07535761131394
GO:0006259~DNA metabolic process | RAD51C, TYMS, FOS, TP53, CENPF, IGF1, TOP2A, BRCA1, SOD2, RAD51 | 10 | 72 | 506 | 13528 | 3.71321914800175 | 0.00126282430158292 | 0.89086066989743 | 0.0120315700872076 | 2.11640745067148
GO:0000075~cell cycle checkpoint | CCND1, TP53, CENPF, BIRC5, BRCA1 | 5 | 72 | 91 | 13528 | 10.3235653235653 | 0.00132001920546456 | 0.901285385200283 | 0.0125055082193685 | 2.21125731413276
GO:0048878~chemical homeostasis | JUN, [NAME], TGM2, TP53, IL1B, IGF1, HP, MAL, STAT3, SOD2 | 10 | 72 | 512 | 13528 | 3.66970486111111 | 0.00137063873430209 | 0.909678327751932 | 0.0129125454080935 | 2.29513067901524
GO:0001942~hair follicle development | AKT1, PTGS2, BCL2, FST | 4 | 72 | 42 | 13528 | 17.8941798941798 | 0.00137339042709509 | 0.910113560560543 | 0.0128692065824664 | 2.29968811996519
GO:0022405~hair cycle process | AKT1, PTGS2, BCL2, FST | 4 | 72 | 42 | 13528 | 17.8941798941798 | 0.00137339042709509 | 0.910113560560543 | 0.0128692065824664 | 2.29968811996519
GO:0022404~molting cycle process | AKT1, PTGS2, BCL2, FST | 4 | 72 | 42 | 13528 | 17.8941798941798 | 0.00137339042709509 | 0.910113560560543 | 0.0128692065824664 | 2.29968811996519
GO:0042303~molting cycle | AKT1, PTGS2, BCL2, FST | 4 | 72 | 43 | 13528 | 17.4780361757105 | 0.00147087064677568 | 0.924251328931177 | 0.0137038155350093 | 2.46100895959995
GO:0042633~hair cycle | AKT1, PTGS2, BCL2, FST | 4 | 72 | 43 | 13528 | 17.4780361757105 | 0.00147087064677568 | 0.924251328931177 | 0.0137038155350093 | 2.46100895959995
GO:0006796~phosphate metabolic process | EGFR, FGFR2, FGFR1, TNF, PIM1, RPS6KB2, PTEN, AKT1, IGF1R, CCND1, BCL2, MAP3K1, IFNG, IL1B | 14 | 72 | 973 | 13528 | 2.70343725019984 | 0.00148138021849221 | 0.925636116578215 | 0.013728220475998 | 2.47838636334012
GO:0006793~phosphorus metabolic process | EGFR, FGFR2, FGFR1, TNF, PIM1, RPS6KB2, PTEN, AKT1, IGF1R, CCND1, BCL2, MAP3K1, IFNG, IL1B | 14 | 72 | 973 | 13528 | 2.70343725019984 | 0.00148138021849221 | 0.925636116578215 | 0.013728220475998 | 2.47838636334012
GO:0034504~protein localization in nucleus | AKT1, TNF, JUN, IFNG, TP53 | 5 | 72 | 94 | 13528 | 9.99408983451536 | 0.00148847319588768 | 0.926556389645707 | 0.0137210668825348 | 2.49011283813331
GO:0009894~regulation of catabolic process | AKT1, TNF, IFNG, IL1B, IGF1 | 5 | 72 | 96 | 13528 | 9.78587962962963 | 0.0016087648558054 | 0.940539063957601 | 0.014745134755108 | 2.68878325689497
GO:0046890~regulation of lipid biosynthetic process | AKT1, TNF, IFNG, BRCA1 | 4 | 72 | 45 | 13528 | 16.7012345679012 | 0.00167861667824057 | 0.947402546114797 | 0.0153010377727911 | 2.80397375692829
GO:0006979~response to oxidative stress | EGFR, FOS, PTGS2, JUN, [NAME], SOD2 | 6 | 72 | 164 | 13528 | 6.87398373983739 | 0.00168334857956166 | 0.947837767220193 | 0.0152645708417074 | 2.81177234854161
[NAME]positive regulation of survival gene product expression | [NAME], [NAME], ESR2 | 3 | 72 | 12 | 13528 | 46.9722222222222 | 0.00173258741987603 | 0.952158409309144 | 0.015627177990088 | 2.89288737844301
[NAME]~response to iron ion | CCND1, CYP1A1, BCL2 | 3 | 72 | 12 | 13528 | 46.9722222222222 | 0.00173258741987603 | 0.952158409309144 | 0.015627177990088 | 2.89288737844301
GO:0045834~positive regulation of lipid metabolic process | AKT1, TNF, IFNG, IL1B | 4 | 72 | 46 | 13528 | 16.3381642512077 | 0.00178901474274954 | 0.956671796165274 | 0.016049966671547 | 2.98576623279364
GO:0002791~regulation of peptide secretion | TNF, IFNG, IL1B, NOS2 | 4 | 72 | 46 | 13528 | 16.3381642512077 | 0.00178901474274954 | 0.956671796165274 | 0.016049966671547 | 2.98576623279364
GO:0045792~negative regulation of cell size | AKT1, BCL2, TP53, ESR2, ENO1 | 5 | 72 | 99 | 13528 | 9.48933782267115 | 0.00180165506572827 | 0.957623013566018 | 0.0160803333092801 | 3.00656062555402
GO:0010740~positive regulation of protein kinase cascade | [NAME], TNF, IFNG, TGM2, [NAME], IGF1 | 6 | 72 | 167 | 13528 | 6.750499001996 | 0.00182291439881596 | 0.959175998967609 | 0.0161863712852287 | 3.04152455572703
GO:0021700~developmental maturation | NRCAM, PGR, AKT1, PTGS2, MMP2 | 5 | 72 | 101 | 13528 | 9.3014301430143 | 0.00193882270640569 | 0.966695250417524 | 0.0171210560888137 | 3.23194339385979
GO:0043406~positive regulation of MAP kinase activity | EGFR, TNF, KRAS, MAP3K1, IL1B | 5 | 72 | 102 | 13528 | 9.21023965141612 | 0.00201004848547208 | 0.970611771211978 | 0.0176562144528503 | 3.34878136391252
GO:0051043~regulation of membrane protein ectodomain proteolysis | TNF, IFNG, IL1B | 3 | 72 | 13 | 13528 | 43.3589743589743 | 0.00204066568024646 | 0.972150546452525 | 0.0178337455618904 | 3.39896466316391
GO:0050995~negative regulation of lipid catabolic process | AKT1, TNF, IL1B | 3 | 72 | 13 | 13528 | 43.3589743589743 | 0.00204066568024646 | 0.972150546452525 | 0.0178337455618904 | 3.39896466316391
GO:0051090~regulation of transcription factor activity | TNF, KRAS, NCOA3, PIM1, IL1B | 5 | 72 | 103 | 13528 | 9.12081984897519 | 0.00208306641128962 | 0.974149465147529 | 0.0181111063369391 | 3.46842135388202
GO:0051259~protein oligomerization | IGF1R, MAP3K1, TGM2, TP53, SOD2, RAD51 | 6 | 72 | 174 | 13528 | 6.47892720306513 | 0.00218140955708646 | 0.978251008625593 | 0.0188654873492859 | 3.62933654332908
GO:0030728~ovulation | PGR, AFP, PTGS2 | 3 | 72 | 14 | 13528 | 40.2619047619047 | 0.00237271318139393 | 0.984459542865408 | 0.0204043443185157 | 3.94163670258621
GO:0045069~regulation of viral genome replication | TNF, [NAME], TOP2A | 3 | 72 | 14 | 13528 | 40.2619047619047 | 0.00237271318139393 | 0.984459542865408 | 0.0204043443185157 | 3.94163670258621
GO:0051345~positive regulation of hydrolase activity | EGFR, TNF, IFNB1, IFNG, TGM2, TP53 | 6 | 72 | 179 | 13528 | 6.29795158286778 | 0.00246725357083698 | 0.986838243057517 | 0.021106293644365 | 4.09562058355535
GO:0042176~regulation of protein catabolic process | AKT1, TNF, IFNG, IL1B | 4 | 72 | 52 | 13528 | 14.4529914529914 | 0.0025467104788859 | 0.988553575696328 | 0.0216738193433312 | 4.22485738782075
GO:0043408~regulation of MAPKKK cascade | AKT1, TNF, MAP3K1, IL1B, NCOR1 | 5 | 72 | 109 | 13528 | 8.61875637104995 | 0.00256009476880645 | 0.988819684692743 | 0.0216815055051736 | 4.24661082667801
GO:0009615~response to virus | TNF, CYP1A1, IFNB1, BCL2, IFNG | 5 | 72 | 109 | 13528 | 8.61875637104995 | 0.00256009476880645 | 0.988819684692743 | 0.0216815055051736 | 4.24661082667801
GO:0045892~negative regulation of transcription, DNA-dependent | TNF, NCOA2, TBX3, FST, TP53, NCOR1, STAT3, ENO1 | 8 | 72 | 356 | 13528 | 4.22222222222222 | 0.00258270326649029 | 0.989255222748185 | 0.021766106771854 | 4.28334577890857
GO:0007166~cell surface receptor linked signal transduction | EGFR, FGFR2, FGFR1, CXCL3, FST, AKAP12, EVL, PTEN, STAT3, AKT1, FOS, IGF1R, CCND1, IFNB1, JUN, MAP3K1, IFNG, TGM2, AREG, NOS2 | 20 | 72 | 1856 | 13528 | 2.02466475095785 | 0.00265110812286777 | 0.990472413240214 | 0.0222301703311784 | 4.39441126185182
GO:0000122~negative regulation of transcription from RNA polymerase II promoter | TNF, NCOA2, FST, TP53, NCOR1, STAT3, ENO1 | 7 | 72 | 266 | 13528 | 4.94444444444444 | 0.00268715338824329 | 0.991057322838875 | 0.0224222995461776 | 4.4528873286874
GO:0030162~regulation of proteolysis | AKT1, TNF, IFNG, IL1B | 4 | 72 | 53 | 13528 | 14.1802935010482 | 0.00268943356016829 | 0.991093092607315 | 0.0223349704282981 | 4.4565853090251
GO:0001889~liver development | AFP, CCND1, CYP1A1, SOD2 | 4 | 72 | 53 | 13528 | 14.1802935010482 | 0.00268943356016829 | 0.991093092607315 | 0.0223349704282981 | 4.4565853090251
GO:0040007~growth | AKT1, FGFR2, FGFR1, PTGS2, BCL2, IGF1 | 6 | 72 | 183 | 13528 | 6.16029143897996 | 0.00271484181764905 | 0.991482134930396 | 0.022437727786997 | 4.49778328307947
GO:0032642~regulation of chemokine production | TNF, IFNG, IL1B | 3 | 72 | 15 | 13528 | 37.5777777777777 | 0.00272847701121272 | 0.991683861666722 | 0.0224436322579953 | 4.51988504373397
GO:0008406~gonad development | PGR, AFP, CCND1, BCL2, FST | 5 | 72 | 112 | 13528 | 8.38789682539682 | 0.00282465316256482 | 0.992977412164489 | 0.0231183138961764 | 4.67564367825702
GO:0019216~regulation of lipid metabolic process | AKT1, TNF, IFNG, IL1B, BRCA1 | 5 | 72 | 112 | 13528 | 8.38789682539682 | 0.00282465316256482 | 0.992977412164489 | 0.0231183138961764 | 4.67564367825702
GO:0051253~negative regulation of RNA metabolic process | TNF, NCOA2, TBX3, FST, TP53, NCOR1, STAT3, ENO1 | 8 | 72 | 362 | 13528 | 4.15224063842848 | 0.00283496762254367 | 0.993103602129088 | 0.0230942026295413 | 4.69233388914178
GO:0032355~response to estradiol stimulus | PTGS2, [NAME], PTEN, STAT3 | 4 | 72 | 54 | 13528 | 13.917695473251 | 0.00283700514522441 | 0.993128260393474 | 0.023003888917684 | 4.69563055503962
GO:0019725~cellular homeostasis | ALDOA, JUN, [NAME], TGM2, TP53, IL1B, HP, MAL, SOD2 | 9 | 72 | 466 | 13528 | 3.62875536480686 | 0.00296427034536449 | 0.994505913165029 | 0.023914444101769 | 4.9013302727795
GO:0050999~regulation of nitric-oxide synthase activity | EGFR, AKT1, KRAS | 3 | 72 | 16 | 13528 | 35.2291666666666 | 0.00310770618700192 | 0.995730641168591 | 0.024944229736569 | 5.13266596221827
GO:0051412~response to corticosterone stimulus | FOS, CCND1, BCL2 | 3 | 72 | 16 | 13528 | 35.2291666666666 | 0.00310770618700192 | 0.995730641168591 | 0.024944229736569 | 5.13266596221827
GO:0007088~regulation of mitosis | TNF, CENPF, IL1B, IGF1 | 4 | 72 | 56 | 13528 | 13.4206349206349 | 0.00314690831091948 | 0.996015042093293 | 0.0251404626563683 | 5.19579959804644
GO:0051783~regulation of nuclear division | TNF, CENPF, IL1B, IGF1 | 4 | 72 | 56 | 13528 | 13.4206349206349 | 0.00314690831091948 | 0.996015042093293 | 0.0251404626563683 | 5.19579959804644
GO:0006260~DNA replication | TYMS, CENPF, IGF1, TOP2A, BRCA1, RAD51 | 6 | 72 | 190 | 13528 | 5.93333333333333 | 0.00319082593946497 | 0.996311225063615 | 0.0253719440039545 | 5.26648043464532
GO:0016477~cell migration | NRCAM, TNF, CXCL3, IFNG, IL1B, ESR2, PTEN | 7 | 72 | 276 | 13528 | 4.76529790660225 | 0.00322543432452808 | 0.996529041955066 | 0.0255284255365101 | 5.3221440812414
GO:0050900~[NAME] migration | TNF, CXCL3, IFNG, IL1B | 4 | 72 | 57 | 13528 | 13.1851851851851 | 0.00330934411823399 | 0.997005268456609 | 0.0260674078161803 | 5.45697569500547
GO:0006974~response to DNA damage stimulus | RAD51C, TYMS, CCND1, TP53, TOP2A, BRCA1, SOD2, RAD51 | 8 | 72 | 373 | 13528 | 4.02978850163836 | 0.00334632661372314 | 0.997193865781971 | 0.0262376486685095 | 5.51634414876172
GO:0006873~cellular ion homeostasis | JUN, [NAME], TGM2, TP53, IL1B, HP, MAL, SOD2 | 8 | 72 | 374 | 13528 | 4.01901366607249 | 0.00339609801559304 | 0.997429081019892 | 0.0265049860545728 | 5.5961874210057
GO:0001558~regulation of cell growth | NRCAM, AKT1, BCL2, TP53, ESR2, ENO1 | 6 | 72 | 194 | 13528 | 5.81099656357388 | 0.00348842847041433 | 0.997814490342085 | 0.0270965505765652 | 5.7441358195822
GO:0055082~cellular chemical homeostasis | JUN, [NAME], TGM2, TP53, IL1B, HP, MAL, SOD2 | 8 | 72 | 380 | 13528 | 3.95555555555555 | 0.00370674643089532 | 0.99851151941317 | 0.0286442446487324 | 6.09309662666809
GO:0006281~DNA repair | RAD51C, TYMS, TP53, TOP2A, BRCA1, SOD2, RAD51 | 7 | 72 | 284 | 13528 | 4.6310641627543 | 0.00371115421308887 | 0.998523018834009 | 0.0285522555363969 | 6.10012951806693
GO:0051101~regulation of DNA binding | TNF, KRAS, NCOA3, PIM1, IL1B | 5 | 72 | 121 | 13528 | 7.76400367309458 | 0.00372974062517646 | 0.998570540216205 | 0.0285683137464842 | 6.12977984720534
GO:0043933~macromolecular complex subunit organization | IGF1R, HSP90AA1, OCLN, MAP3K1, TGM2, TP53, CENPF, EVL, STMN1, SOD2, RAD51 | 11 | 72 | 710 | 13528 | 2.91095461658841 | 0.00377659166154153 | 0.99868365714871 | 0.0287970437613472 | 6.2044807724223
GO:0051091~positive regulation of transcription factor activity | TNF, KRAS, NCOA3, IL1B | 4 | 72 | 60 | 13528 | 12.5259259259259 | 0.00382718891174905 | 0.998795792298574 | 0.0290518048749282 | 6.28509196755507
GO:0048609~reproductive process in a multicellular organism | EGFR, PGR, AKT1, RAD51C, AFP, PTGS2, CYP1A1, BCL2, FST | 9 | 72 | 487 | 13528 | 3.47227926078028 | 0.00387533551156926 | 0.998893618760409 | 0.0292860131362336 | 6.3617382712528
[NAME]~multicellular organism reproduction | EGFR, PGR, AKT1, RAD51C, AFP, PTGS2, CYP1A1, BCL2, FST | 9 | 72 | 487 | 13528 | 3.47227926078028 | 0.00387533551156926 | 0.998893618760409 | 0.0292860131362336 | 6.3617382712528
GO:0030593~neutrophil chemotaxis | CXCL3, IFNG, IL1B | 3 | 72 | 18 | 13528 | 31.3148148148148 | 0.0039355662161437 | 0.999004891847468 | 0.0296078780113734 | 6.45753864963357
GO:0040014~regulation of multicellular organism growth | AKT1, BCL2, IGF1, STAT3 | 4 | 72 | 61 | 13528 | 12.3205828779599 | 0.00401014297554518 | 0.99912729558526 | 0.0300329068645064 | 6.57602946195183
GO:0009636~response to toxin | TYMS, FOS, CYP1A1, BCL2 | 4 | 72 | 61 | 13528 | 12.3205828779599 | 0.00401014297554518 | 0.99912729558526 | 0.0300329068645064 | 6.57602946195183
GO:0006302~double-strand break repair | TP53, [NAME], SOD2, RAD51 | 4 | 72 | 62 | 13528 | 12.1218637992831 | 0.00419834375211751 | 0.999373391894021 | 0.0312896312282658 | 6.87442348554343
GO:0048608~reproductive structure development | PGR, AFP, CCND1, BCL2, FST | 5 | 72 | 126 | 13528 | 7.45590828924162 | 0.00430909325198569 | 0.999484391333159 | 0.0319678386437569 | 7.04959844456897
GO:0030879~mammary gland development | PGR, IGF1R, TBX3, IGF1 | 4 | 72 | 63 | 13528 | 11.9294532627865 | 0.00439183584110495 | 0.999554290881323 | 0.0324359864479775 | 7.18027184285037
GO:0048511~rhythmic process | EGFR, PGR, AFP, JUN, BCL2 | 5 | 72 | 128 | 13528 | 7.33940972222222 | 0.00455693179200884 | 0.999666730133897 | 0.0334965971286298 | 7.44048758034485
GO:0045471~response to ethanol | CCND1, BCL2, PTEN, STAT3 | 4 | 72 | 64 | 13528 | 11.7430555555555 | 0.00459066273486653 | 0.999685950525753 | 0.0336003333178509 | 7.49356803935965
GO:0008585~female gonad development | PGR, AFP, BCL2, FST | 4 | 72 | 64 | 13528 | 11.7430555555555 | 0.00459066273486653 | 0.999685950525753 | 0.0336003333178509 | 7.49356803935965
GO:0007292~female gamete generation | PGR, AFP, PTGS2, BCL2 | 4 | 72 | 65 | 13528 | 11.5623931623931 | 0.0047948668302816 | 0.999780820075427 | 0.0349266103464334 | 7.81430130390349
GO:0070271~protein complex biogenesis | IGF1R, HSP90AA1, OCLN, MAP3K1, TGM2, TP53, CENPF, SOD2, RAD51 | 9 | 72 | 505 | 13528 | 3.34851485148514 | 0.00481769414900171 | 0.999789458366415 | 0.0349454997255139 | 7.8500899500401
GO:0006461~protein complex assembly | IGF1R, HSP90AA1, OCLN, MAP3K1, TGM2, TP53, CENPF, SOD2, RAD51 | 9 | 72 | 505 | 13528 | 3.34851485148514 | 0.00481769414900171 | 0.999789458366415 | 0.0349454997255139 | 7.8500899500401
GO:0045913~positive regulation of carbohydrate metabolic process | AKT1, IFNG, IGF1 | 3 | 72 | 20 | 13528 | 28.1833333333333 | 0.0048543235129371 | 0.999802614216131 | 0.0350623999445188 | 7.90749010976334
GO:0010676~positive regulation of cellular carbohydrate metabolic process | AKT1, IFNG, IGF1 | 3 | 72 | 20 | 13528 | 28.1833333333333 | 0.0048543235129371 | 0.999802614216131 | 0.0350623999445188 | 7.90749010976334
GO:0017038~protein import | AKT1, TNF, JUN, IFNG, TP53 | 5 | 72 | 131 | 13528 | 7.17133163698049 | 0.00494645296086633 | 0.999832185053935 | 0.0355712960358249 | 8.05171316438102
GO:0006800~oxygen and reactive oxygen species metabolic process | CYP1A1, [NAME], [NAME], SOD2 | 4 | 72 | 67 | 13528 | 11.2172470978441 | 0.00521957081343293 | 0.999896285678912 | 0.0373504536704537 | 8.47801473272069
GO:0042698~ovulation cycle | EGFR, PGR, AFP, BCL2 | 4 | 72 | 67 | 13528 | 11.2172470978441 | 0.00521957081343293 | 0.999896285678912 | 0.0373504536704537 | 8.47801473272069
GO:0046889~positive regulation of lipid biosynthetic process | AKT1, TNF, IFNG | 3 | 72 | 21 | 13528 | 26.8412698412698 | 0.00534718131828365 | 0.99991717327158 | 0.0380933304975988 | 8.67656009220828
[NAME]~response to hypoxia | CYP1A1, [NAME], NOS2, MMP2, SOD2 | 5 | 72 | 134 | 13528 | 7.01077943615257 | 0.00535777538979637 | 0.999918705409976 | 0.0380134988084778 | 8.69302485817207
GO:0006605~protein targeting | AKT1, TNF, JUN, IFNG, AKAP12, TP53 | 6 | 72 | 215 | 13528 | 5.24341085271317 | 0.00538714050557928 | 0.999922805796432 | 0.0380647517670127 | 8.73864802475267
GO:0048870~cell motility | NRCAM, TNF, CXCL3, IFNG, IL1B, ESR2, PTEN | 7 | 72 | 307 | 13528 | 4.28411147303655 | 0.00541193108167057 | 0.999926106079001 | 0.038083934001809 | 8.77714725053276
GO:0051674~localization of cell | NRCAM, TNF, CXCL3, IFNG, IL1B, ESR2, PTEN | 7 | 72 | 307 | 13528 | 4.28411147303655 | 0.00541193108167057 | 0.999926106079001 | 0.038083934001809 | 8.77714725053276
GO:0050730~regulation of peptidyl-tyrosine phosphorylation | EGFR, [NAME], IFNG, IGF1 | 4 | 72 | 68 | 13528 | 11.0522875816993 | 0.00544015013051047 | 0.999929691500667 | 0.0381265928240786 | 8.82095222177113
GO:0045596~negative regulation of cell differentiation | CCND1, TBX3, FST, TP53, IGF1, SOD2 | 6 | 72 | 216 | 13528 | 5.21913580246913 | 0.00549268619798555 | 0.999935909844919 | 0.0383358047817147 | 8.90245224827545
GO:0050801~ion homeostasis | JUN, [NAME], TGM2, TP53, IL1B, HP, MAL, SOD2 | 8 | 72 | 409 | 13528 | 3.67508829122521 | 0.00552469165313875 | 0.999939425475174 | 0.0384029885775943 | 8.95206920928576
GO:0033043~regulation of organelle organization | TNF, MAP3K1, CENPF, IL1B, IGF1, BRCA1 | 6 | 72 | 217 | 13528 | 5.19508448540706 | 0.00559969015698105 | 0.999946927087256 | 0.0387622571923138 | 9.06823723371534
GO:0031099~regeneration | AFP, CCND1, BCL2, IGF1 | 4 | 72 | 69 | 13528 | 10.8921095008051 | 0.00566626553270584 | 0.999952804482655 | 0.0390614795015066 | 9.1712414941497
GO:0030155~regulation of cell adhesion | TNF, BCL2, TGM2, [NAME], PTEN | 5 | 72 | 137 | 13528 | 6.85725871857258 | 0.00579143485258581 | 0.999962150687309 | 0.0397535700813278 | 9.36460410507259
GO:0043525~positive regulation of neuron apoptosis | TNF, JUN, TP53 | 3 | 72 | 22 | 13528 | 25.6212121212121 | 0.00586203838124633 | 0.99996658117229 | 0.040073324795089 | 9.4735021014146
GO:0043388~positive regulation of DNA binding | TNF, KRAS, NCOA3, IL1B | 4 | 72 | 70 | 13528 | 10.7365079365079 | 0.00589795412502413 | 0.999968632047516 | 0.0401584407830858 | 9.52885084018646
[NAME]~regulation of protein localization | AKT1, TNF, BCL2, IFNG, IL1B | 5 | 72 | 138 | 13528 | 6.80756843800322 | 0.00594104275986279 | 0.999970927212908 | 0.0402906824002899 | 9.59521150328307
GO:0006986~response to unfolded protein | CCND1, HSP90AA1, IFNG, [NAME] | 4 | 72 | 71 | 13528 | 10.5852895148669 | 0.00613525198989815 | 0.999979358871056 | 0.0414243214279823 | 9.89374446847675
GO:0050678~regulation of epithelial cell proliferation | EGFR, PGR, IGF1, ESR2 | 4 | 72 | 71 | 13528 | 10.5852895148669 | 0.00613525198989815 | 0.999979358871056 | 0.0414243214279823 | 9.89374446847675
GO:0042531~positive regulation of tyrosine phosphorylation of STAT protein | CSF2, IFNG, IGF1 | 3 | 72 | 23 | 13528 | 24.5072463768115 | 0.0063986568712793 | 0.999987030183264 | 0.0430044952057884 | 10.2971610790281
GO:0010332~response to gamma radiation | BCL2, TP53, SOD2 | 3 | 72 | 23 | 13528 | 24.5072463768115 | 0.0063986568712793 | 0.999987030183264 | 0.0430044952057884 | 10.2971610790281
GO:0043271~negative regulation of ion transport | TNF, PTGS2, BCL2 | 3 | 72 | 23 | 13528 | 24.5072463768115 | 0.0063986568712793 | 0.999987030183264 | 0.0430044952057884 | 10.2971610790281
GO:0070482~response to oxygen levels | CYP1A1, [NAME], NOS2, MMP2, SOD2 | 5 | 72 | 141 | 13528 | 6.66272655634357 | 0.0064052985987595 | 0.999987181276161 | 0.0428844401553988 | 10.3073111880416
GO:0043405~regulation of MAP kinase activity | EGFR, TNF, KRAS, MAP3K1, IL1B | 5 | 72 | 141 | 13528 | 6.66272655634357 | 0.0064052985987595 | 0.999987181276161 | 0.0428844401553988 | 10.3073111880416
GO:0006917~induction of apoptosis | TNF, IFNB1, TGM2, TP53, MAL, PTEN, BRCA1 | 7 | 72 | 320 | 13528 | 4.11006944444444 | 0.00659546597180229 | 0.999990835270852 | 0.0439660125578049 | 10.5974732773858
GO:0012502~induction of programmed cell death | TNF, IFNB1, TGM2, TP53, MAL, PTEN, BRCA1 | 7 | 72 | 321 | 13528 | 4.09726548978885 | 0.00669372185445741 | 0.999992294243644 | 0.0444399730387029 | 10.7470482391773
GO:0000302~response to reactive oxygen species | FOS, JUN, [NAME], SOD2 | 4 | 72 | 75 | 13528 | 10.0207407407407 | 0.00714122270742936 | 0.999996502549489 | 0.0471721794305396 | 11.4253055279046
GO:0033365~protein localization in organelle | AKT1, TNF, JUN, IFNG, TP53 | 5 | 72 | 146 | 13528 | 6.43455098934551 | 0.00723161994971339 | 0.999997018516896 | 0.0475783857302085 | 11.5617265293243
GO:0051969~regulation of transmission of nerve impulse | EGFR, TNF, KRAS, PTGS2, IFNG | 5 | 72 | 147 | 13528 | 6.39077853363567 | 0.00740493322821743 | 0.999997804603062 | 0.0485133010129715 | 11.8227257380979
GO:0000279~M phase | RAD51C, CENPF, BIRC5, STMN1, UBE2C, NCOR1, RAD51 | 7 | 72 | 329 | 13528 | 3.99763593380614 | 0.00751860178626463 | 0.999998203924749 | 0.0490595414649415 | 11.9935099094759
GO:0051785~positive regulation of nuclear division | TNF, IL1B, IGF1 | 3 | 72 | 25 | 13528 | 22.5466666666666 | 0.00753623594275586 | 0.999998259005095 | 0.0489905356459937 | 12.0199768851484
GO:0045840~positive regulation of mitosis | TNF, IL1B, IGF1 | 3 | 72 | 25 | 13528 | 22.5466666666666 | 0.00753623594275586 | 0.999998259005095 | 0.0489905356459937 | 12.0199768851484
[NAME]~cytoskeleton organization | ALDOA, KRAS, BCL2, EVL, STMN1, UBE2C, NCOR1, BRCA1 | 8 | 72 | 436 | 13528 | 3.44750254841997 | 0.007756935099744 | 0.999998821090379 | 0.0502086099426039 | 12.3505898317361
GO:0030182~neuron differentiation | EGFR, NRCAM, IGF1R, FGFR1, BCL2, PTEN, STAT3, SOD2 | 8 | 72 | 438 | 13528 | 3.43176052765093 | 0.00794547469654569 | 0.999999155098637 | 0.0512136157184599 | 12.6321006934835
GO:0051099~positive regulation of binding | TNF, KRAS, NCOA3, IL1B | 4 | 72 | 78 | 13528 | 9.63532763532763 | 0.00795621832430055 | 0.999999170987388 | 0.0510942562896129 | 12.6481164922413
GO:0046427~positive regulation of JAK-STAT cascade | CSF2, IFNG, IGF1 | 3 | 72 | 26 | 13528 | 21.6794871794871 | 0.00813672996028 | 0.999999397413265 | 0.0520375869618062 | 12.9167969880803
GO:0050994~regulation of lipid catabolic process | AKT1, TNF, IL1B | 3 | 72 | 26 | 13528 | 21.6794871794871 | 0.00813672996028 | 0.999999397413265 | 0.0520375869618062 | 12.9167969880803
GO:0043281~regulation of caspase activity | TNF, IFNB1, TP53, BIRC5 | 4 | 72 | 79 | 13528 | 9.51336146272855 | 0.00823957049913524 | 0.999999497566241 | 0.0524897078591818 | 13.0695209204833
GO:0051336~regulation of hydrolase activity | EGFR, TNF, IFNB1, IFNG, TGM2, TP53, BIRC5 | 7 | 72 | 337 | 13528 | 3.90273656445763 | 0.0084148782539463 | 0.999999631452816 | 0.0533875836235635 | 13.3292818869275
GO:0031644~regulation of neurological system process | EGFR, TNF, KRAS, PTGS2, IFNG | 5 | 72 | 153 | 13528 | 6.14015976761074 | 0.00850264467538207 | 0.999999684423322 | 0.0537378754660619 | 13.45905461151
[NAME] development | EGFR, NRCAM, IGF1R, FGFR1, BCL2, PTEN, SOD2 | 7 | 72 | 339 | 13528 | 3.87971156997705 | 0.00865049150125613 | 0.999999757018784 | 0.054454890858373 | 13.6772497907517
GO:0045786~negative regulation of cell cycle | EGFR, [NAME], TP53, CENPF | 4 | 72 | 81 | 13528 | 9.27846364883402 | 0.0088239710883689 | 0.99999982121322 | 0.0553231345970198 | 13.9326142434884
GO:0006913~nucleocytoplasmic transport | AKT1, TNF, JUN, IFNG, TP53 | 5 | 72 | 156 | 13528 | 6.02207977207977 | 0.00908944852239788 | 0.999999888211799 | 0.0567448558457326 | 14.322025068583
GO:0052548~regulation of endopeptidase activity | TNF, IFNB1, TP53, BIRC5 | 4 | 72 | 82 | 13528 | 9.16531165311653 | 0.00912507158174354 | 0.999999895039421 | 0.0567606430838651 | 14.3741517853863
GO:0010638~positive regulation of organelle organization | TNF, MAP3K1, [NAME], IGF1 | 4 | 72 | 83 | 13528 | 9.05488621151271 | 0.00943213877386312 | 0.999999939037757 | 0.0584163331223128 | 14.8222432560682
GO:0009266~response to temperature stimulus | AKT1, FOS, [NAME], IL1B | 4 | 72 | 83 | 13528 | 9.05488621151271 | 0.00943213877386312 | 0.999999939037757 | 0.0584163331223128 | 14.8222432560682
[NAME]nuclear transport | AKT1, TNF, JUN, IFNG, TP53 | 5 | 72 | 158 | 13528 | 5.94585091420534 | 0.00949501089993715 | 0.999999945457136 | 0.0585899348083324 | 14.9137176093761
[NAME]negative regulation of cell communication | AKT1, CCND1, PTGS2, IL1B, NCOR1, PTEN | 6 | 72 | 248 | 13528 | 4.54569892473118 | 0.00969723753980452 | 0.999999961868193 | 0.0595970487540854 | 15.2073162055276
GO:0019953~sexual reproduction | PGR, AKT1, RAD51C, AFP, PTGS2, BCL2, FST, STAT3 | 8 | 72 | 458 | 13528 | 3.28190198932557 | 0.0100228260899692 | 0.999999978573932 | 0.0613312954561157 | 15.6780132377828
GO:0052547~regulation of peptidase activity | TNF, IFNB1, TP53, BIRC5 | 4 | 72 | 86 | 13528 | 8.73901808785529 | 0.0103893744660304 | 0.999999988805491 | 0.0632933803131395 | 16.2049827779713
GO:0060557~positive regulation of vitamin D biosynthetic process | TNF, IFNG | 2 | 72 | 2 | 13528 | 187.888888888888 | 0.0104695880158145 | 0.999999990288342 | 0.063549060293109 | 16.3198880625931
GO:0002439~chronic inflammatory response to antigenic stimulus | TNF, IL1B | 2 | 72 | 2 | 13528 | 187.888888888888 | 0.0104695880158145 | 0.999999990288342 | 0.063549060293109 | 16.3198880625931
GO:0034116~positive regulation of heterotypic cell-cell adhesion | TNF, IL1B | 2 | 72 | 2 | 13528 | 187.888888888888 | 0.0104695880158145 | 0.999999990288342 | 0.063549060293109 | 16.3198880625931
GO:0046136~positive regulation of vitamin metabolic process | TNF, IFNG | 2 | 72 | 2 | 13528 | 187.888888888888 | 0.0104695880158145 | 0.999999990288342 | 0.063549060293109 | 16.3198880625931
GO:0048589~developmental growth | AKT1, PTGS2, BCL2, IGF1 | 4 | 72 | 87 | 13528 | 8.63856960408684 | 0.0107205380848249 | 0.999999993774207 | 0.0648066728807735 | 16.6784153590366
GO:0043467~regulation of generation of precursor metabolites and energy | AKT1, IGF1, NOS2 | 3 | 72 | 30 | 13528 | 18.7888888888888 | 0.0107447095421897 | 0.999999994035242 | 0.064726798881654 | 16.7128722122095
[NAME]neuron projection development | EGFR, NRCAM, IGF1R, FGFR1, BCL2, PTEN | 6 | 72 | 256 | 13528 | 4.40364583333333 | 0.0110212056952686 | 0.999999996345944 | 0.0661191674800312 | 17.1060698336063
GO:0030335~positive regulation of cell migration | EGFR, IGF1R, [NAME], IGF1 | 4 | 72 | 89 | 13528 | 8.44444444444444 | 0.0114011166909303 | 0.999999998136786 | 0.0680999342604904 | 17.6434828578767
GO:0042509~regulation of tyrosine phosphorylation of STAT protein | CSF2, IFNG, IGF1 | 3 | 72 | 31 | 13528 | 18.1827956989247 | 0.0114470744967504 | 0.999999998282606 | 0.068135662966558 | 17.708270938415
GO:0043900~regulation of multi-organism process | IFNB1, IFNG, NOS2 | 3 | 72 | 31 | 13528 | 18.1827956989247 | 0.0114470744967504 | 0.999999998282606 | 0.068135662966558 | 17.708270938415
GO:0007006~mitochondrial membrane organization | HSP90AA1, [NAME], TP53 | 3 | 72 | 32 | 13528 | 17.6145833333333 | 0.0121691412651725 | 0.999999999522934 | 0.0720572585674568 | 18.7199151129316
GO:0030308~negative regulation of cell growth | BCL2, TP53, ESR2, ENO1 | 4 | 72 | 92 | 13528 | 8.16908212560386 | 0.0124678947486095 | 0.999999999719265 | 0.0735236062758104 | 19.1350483838057
[NAME]~cell projection organization | EGFR, NRCAM, AKT1, IGF1R, FGFR1, BCL2, PTEN | 7 | 72 | 368 | 13528 | 3.57397342995169 | 0.0126229165894772 | 0.999999999786806 | 0.0741608257009249 | 19.3496721813265
[NAME]~response to endoplasmic reticulum stress | CCND1, IFNG, TP53 | 3 | 72 | 34 | 13528 | 16.578431372549 | 0.0136715016321316 | 0.999999999966899 | 0.0798439388903172 | 20.7873982429315
GO:0050806~positive regulation of synaptic transmission | EGFR, TNF, PTGS2 | 3 | 72 | 34 | 13528 | 16.578431372549 | 0.0136715016321316 | 0.999999999966899 | 0.0798439388903172 | 20.7873982429315
GO:0010827~regulation of glucose transport | AKT1, TNF, IL1B | 3 | 72 | 34 | 13528 | 16.578431372549 | 0.0136715016321316 | 0.999999999966899 | 0.0798439388903172 | 20.7873982429315
GO:0048145~regulation of fibroblast proliferation | TP53, IGF1, SOD2 | 3 | 72 | 35 | 13528 | 16.1047619047619 | 0.014451360191208 | 0.999999999991727 | 0.0839560658341374 | 21.8409955684881
GO:0006984~ER-nuclear signaling pathway | CCND1, IFNG, TP53 | 3 | 72 | 35 | 13528 | 16.1047619047619 | 0.014451360191208 | 0.999999999991727 | 0.0839560658341374 | 21.8409955684881
[NAME]~membrane organization | EGFR, NRCAM, HSP90AA1, KRAS, BCL2, TP53, MAL | 7 | 72 | 381 | 13528 | 3.45202682997958 | 0.0147660774893033 | 0.999999999995274 | 0.0854361858025452 | 22.262435965022
GO:0051272~positive regulation of cell motion | EGFR, IGF1R, [NAME], IGF1 | 4 | 72 | 98 | 13528 | 7.66893424036281 | 0.0147683514924109 | 0.999999999995293 | 0.0851700122640881 | 22.2654733049466
GO:0040017~positive regulation of locomotion | EGFR, IGF1R, [NAME], IGF1 | 4 | 72 | 98 | 13528 | 7.66893424036281 | 0.0147683514924109 | 0.999999999995293 | 0.0851700122640881 | 22.2654733049466
GO:0016337~cell-cell adhesion | EGFR, NRCAM, TNF, CLDN4, BCL2, [NAME] | 6 | 72 | 276 | 13528 | 4.08454106280193 | 0.0148619945793443 | 0.999999999996015 | 0.0854114702176009 | 22.3904535476207
GO:0051130~positive regulation of cellular component organization | AKT1, TNF, MAP3K1, [NAME], IGF1 | 5 | 72 | 181 | 13528 | 5.1903007980356 | 0.0150254535565487 | 0.999999999997021 | 0.0860363068409642 | 22.6081602471946
GO:0043269~regulation of ion transport | AKT1, TNF, PTGS2, BCL2 | 4 | 72 | 99 | 13528 | 7.59147025813692 | 0.015173560755779 | 0.999999999997711 | 0.0865723248731089 | 22.804923989918
GO:0032675~regulation of interleukin-6 production | TNF, IFNG, IL1B | 3 | 72 | 36 | 13528 | 15.6574074074074 | 0.0152500504602982 | 0.999999999998002 | 0.0867125777706625 | 22.9063578655859
GO:0001776~[NAME] homeostasis | AKT1, BCL2, IFNG | 3 | 72 | 36 | 13528 | 15.6574074074074 | 0.0152500504602982 | 0.999999999998002 | 0.0867125777706625 | 22.9063578655859
GO:0010741~negative regulation of protein kinase cascade | AKT1, NCOR1, PTEN | 3 | 72 | 36 | 13528 | 15.6574074074074 | 0.0152500504602982 | 0.999999999998002 | 0.0867125777706625 | 22.9063578655859
GO:0046425~regulation of JAK-STAT cascade | CSF2, IFNG, IGF1 | 3 | 72 | 36 | 13528 | 15.6574074074074 | 0.0152500504602982 | 0.999999999998002 | 0.0867125777706625 | 22.9063578655859
GO:0048585~negative regulation of response to stimulus | AKT1, IL1B, ESR2, NCOR1 | 4 | 72 | 100 | 13528 | 7.51555555555555 | 0.015585030698172 | 0.9999999999989 | 0.0882611274827435 | 23.3491035684671
GO:0070587~regulation of cell-cell adhesion involved in gastrulation | TNF, IL1B | 2 | 72 | 3 | 13528 | 125.259259259259 | 0.0156637813659153 | 0.999999999999043 | 0.0884069923579633 | 23.4528409676918
GO:0030730~sequestering of triglyceride | TNF, IL1B | 2 | 72 | 3 | 13528 | 125.259259259259 | 0.0156637813659153 | 0.999999999999043 | 0.0884069923579633 | 23.4528409676918
GO:0034114~regulation of heterotypic cell-cell adhesion | TNF, IL1B | 2 | 72 | 3 | 13528 | 125.259259259259 | 0.0156637813659153 | 0.999999999999043 | 0.0884069923579633 | 23.4528409676918
GO:0043902~positive regulation of multi-organism process | IFNG, NOS2 | 2 | 72 | 3 | 13528 | 125.259259259259 | 0.0156637813659153 | 0.999999999999043 | 0.0884069923579633 | 23.4528409676918
GO:0051712~positive regulation of killing of cells of another organism | IFNG, NOS2 | 2 | 72 | 3 | 13528 | 125.259259259259 | 0.0156637813659153 | 0.999999999999043 | 0.0884069923579633 | 23.4528409676918
GO:0010470~regulation of gastrulation | TNF, IL1B | 2 | 72 | 3 | 13528 | 125.259259259259 | 0.0156637813659153 | 0.999999999999043 | 0.0884069923579633 | 23.4528409676918
GO:0000165~MAPKKK cascade | EGFR, FGFR1, TNF, MAP3K1, IL1B | 5 | 72 | 184 | 13528 | 5.10567632850241 | 0.015869399154748 | 0.999999999999337 | 0.0892381695757292 | 23.7230766471628
GO:0002697~regulation of immune effector process | TNF, IFNG, IL1B, NOS2 | 4 | 72 | 101 | 13528 | 7.44114411441144 | 0.0160027717591429 | 0.999999999999477 | 0.0896741251122867 | 23.8978829675652
GO:0051971~positive regulation of transmission of nerve impulse | EGFR, TNF, PTGS2 | 3 | 72 | 37 | 13528 | 15.2342342342342 | 0.0160673591328464 | 0.999999999999534 | 0.0897377677182228 | 23.9823996090082
GO:0009895~negative regulation of catabolic process | AKT1, TNF, IL1B | 3 | 72 | 37 | 13528 | 15.2342342342342 | 0.0160673591328464 | 0.999999999999534 | 0.0897377677182228 | 23.9823996090082
GO:0030595~[NAME] chemotaxis | CXCL3, IFNG, IL1B | 3 | 72 | 37 | 13528 | 15.2342342342342 | 0.0160673591328464 | 0.999999999999534 | 0.0897377677182228 | 23.9823996090082
GO:0007178~[NAME] receptor protein serine/threonine kinase signaling pathway | FOS, MAP3K1, JUN, FST | 4 | 72 | 103 | 13528 | 7.29665587918015 | 0.0168571054938577 | 0.999999999999886 | 0.0936754235686372 | 25.0087158219819
GO:0010675~regulation of cellular carbohydrate metabolic process | AKT1, IFNG, IGF1 | 3 | 72 | 38 | 13528 | 14.8333333333333 | 0.0169030745672553 | 0.999999999999895 | 0.0936265570994887 | 25.0680516401116
GO:0055080~cation homeostasis | BCL2, TGM2, TP53, IL1B, HP, SOD2 | 6 | 72 | 286 | 13528 | 3.94172494172494 | 0.0170833048678375 | 0.999999999999923 | 0.0942893091721536 | 25.3002628933819
GO:0001775~cell activation | EGFR, [NAME], TNF, IFNB1, BCL2, TP53 | 6 | 72 | 287 | 13528 | 3.92799070847851 | 0.0173169331769083 | 0.999999999999949 | 0.0952291107809097 | 25.6002652409318
GO:0007276~gamete generation | PGR, AKT1, RAD51C, AFP, PTGS2, BCL2, FST | 7 | 72 | 395 | 13528 | 3.32967651195499 | 0.0173458809843033 | 0.999999999999952 | 0.0950863608043166 | 25.6373581127958
GO:0007613~memory | PTGS2, [NAME], PTEN | 3 | 72 | 39 | 13528 | 14.4529914529914 | 0.0177569867747134 | 0.999999999999977 | 0.0969460644466011 | 26.1622623016788
GO:0006109~regulation of carbohydrate metabolic process | AKT1, IFNG, IGF1 | 3 | 72 | 39 | 13528 | 14.4529914529914 | 0.0177569867747134 | 0.999999999999977 | 0.0969460644466011 | 26.1622623016788
GO:0060326~cell chemotaxis | CXCL3, IFNG, IL1B | 3 | 72 | 39 | 13528 | 14.4529914529914 | 0.0177569867747134 | 0.999999999999977 | 0.0969460644466011 | 26.1622623016788
GO:0031646~positive regulation of neurological system process | EGFR, TNF, PTGS2 | 3 | 72 | 39 | 13528 | 14.4529914529914 | 0.0177569867747134 | 0.999999999999977 | 0.0969460644466011 | 26.1622623016788
GO:0051262~protein tetramerization | IGF1R, TP53, SOD2 | 3 | 72 | 39 | 13528 | 14.4529914529914 | 0.0177569867747134 | 0.999999999999977 | 0.0969460644466011 | 26.1622623016788
GO:0051960~regulation of nervous system development | NRCAM, BCL2, IFNG, TP53, IGF1 | 5 | 72 | 192 | 13528 | 4.89293981481481 | 0.0182643393028952 | 0.99999999999999 | 0.0992919119208486 | 26.8052495589891
GO:0051092~positive regulation of NF-kappaB transcription factor activity | TNF, KRAS, IL1B | 3 | 72 | 41 | 13528 | 13.7479674796747 | 0.0195185697563315 | 0.999999999999999 | 0.105477984022715 | 28.3722467067674
GO:0007565~female pregnancy | FOS, PTGS2, [NAME], IL1B | 4 | 72 | 110 | 13528 | 6.83232323232323 | 0.0200460235630415 | 0.999999999999999 | 0.107867334970744 | 29.0217561175239
GO:0045926~negative regulation of growth | BCL2, TP53, ESR2, ENO1 | 4 | 72 | 110 | 13528 | 6.83232323232323 | 0.0200460235630415 | 0.999999999999999 | 0.107867334970744 | 29.0217561175239
[NAME] | IFNB1, BCL2, TP53 | 3 | 72 | 42 | 13528 | 13.4206349206349 | 0.02042582872275 | 0.999999999999999 | 0.109482602156705 | 29.4860138540577
GO:0034613~cellular protein localization | EGFR, AKT1, TNF, JUN, IFNG, AKAP12, TP53 | 7 | 72 | 411 | 13528 | 3.2000540686672 | 0.0206583799100841 | 0.999999999999999 | 0.110336461800772 | 29.7688626439765
GO:0051798~positive regulation of hair follicle development | TNF, FST | 2 | 72 | 4 | 13528 | 93.9444444444444 | 0.0208310916451153 | 0.999999999999999 | 0.11088104551186 | 29.9782383164061
GO:0051709~regulation of killing of cells of another organism | IFNG, NOS2 | 2 | 72 | 4 | 13528 | 93.9444444444444 | 0.0208310916451153 | 0.999999999999999 | 0.11088104551186 | 29.9782383164061
GO:0002437~inflammatory response to antigenic stimulus | TNF, IL1B | 2 | 72 | 4 | 13528 | 93.9444444444444 | 0.0208310916451153 | 0.999999999999999 | 0.11088104551186 | 29.9782383164061
GO:0031536~positive regulation of exit from mitosis | BIRC5, UBE2C | 2 | 72 | 4 | 13528 | 93.9444444444444 | 0.0208310916451153 | 0.999999999999999 | 0.11088104551186 | 29.9782383164061
GO:0030656~regulation of vitamin metabolic process | TNF, IFNG | 2 | 72 | 4 | 13528 | 93.9444444444444 | 0.0208310916451153 | 0.999999999999999 | 0.11088104551186 | 29.9782383164061
GO:0060556~regulation of vitamin D biosynthetic process | TNF, IFNG | 2 | 72 | 4 | 13528 | 93.9444444444444 | 0.0208310916451153 | 0.999999999999999 | 0.11088104551186 | 29.9782383164061
GO:0042742~defense response to bacterium | TNF, IFNB1, IFNG, NOS2 | 4 | 72 | 112 | 13528 | 6.71031746031746 | 0.0210141176361995 | 0.999999999999999 | 0.111474092293069 | 30.1994767316072
[NAME]~cellular macromolecule localization | EGFR, AKT1, TNF, JUN, IFNG, AKAP12, TP53 | 7 | 72 | 414 | 13528 | 3.17686527106816 | 0.0213243603744577 | 1 | 0.112703191969626 | 30.5729907151867
GO:0007093~mitotic cell cycle checkpoint | CCND1, TP53, CENPF | 3 | 72 | 43 | 13528 | 13.1085271317829 | 0.0213504608240969 | 1 | 0.112499330767451 | 30.6043282034137
GO:0051046~regulation of secretion | TNF, FST, IFNG, IL1B, NOS2 | 5 | 72 | 202 | 13528 | 4.65071507150715 | 0.0215599116889016 | 1 | 0.113213151510439 | 30.8553237412806
GO:0008202~steroid metabolic process | CYP3A4, AFP, CYP1B1, CYP1A1, CYP19A1 | 5 | 72 | 202 | 13528 | 4.65071507150715 | 0.0215599116889016 | 1 | 0.113213151510439 | 30.8553237412806
GO:0032943~[NAME] cell proliferation | IFNB1, BCL2, TP53 | 3 | 72 | 44 | 13528 | 12.810606060606 | 0.0222922641745014 | 1 | 0.11652183231697 | 31.7262401109806
GO:0070661~leukocyte proliferation | IFNB1, BCL2, TP53 | 3 | 72 | 44 | 13528 | 12.810606060606 | 0.0222922641745014 | 1 | 0.11652183231697 | 31.7262401109806
GO:0065003~macromolecular complex assembly | IGF1R, HSP90AA1, OCLN, MAP3K1, TGM2, TP53, CENPF, SOD2, RAD51 | 9 | 72 | 665 | 13528 | 2.54285714285714 | 0.0227408032532506 | 1 | 0.118398642462149 | 32.2545366217794
GO:0007051~spindle organization | STMN1, UBE2C, NCOR1 | 3 | 72 | 45 | 13528 | 12.5259259259259 | 0.0232510384765943 | 1 | 0.120564222521892 | 32.8508227380281
GO:0016567~protein ubiquitination | AKT1, MAP3K1, UBE2C, BRCA1 | 4 | 72 | 119 | 13528 | 6.31559290382819 | 0.0246023471013145 | 1 | 0.126819288689843 | 34.4062597329377
GO:0048514~blood vessel morphogenesis | JUN, TGM2, [NAME], NOS2, PTEN | 5 | 72 | 211 | 13528 | 4.45234333859926 | 0.0248196332932533 | 1 | 0.127508210252727 | 34.653182555852
GO:0050731~positive regulation of peptidyl-tyrosine phosphorylation | CSF2, IFNG, IGF1 | 3 | 72 | 47 | 13528 | 11.9929078014184 | 0.0252187066209343 | 1 | 0.129071706436794 | 35.1044105849098
GO:0070201~regulation of establishment of protein localization | AKT1, TNF, IFNG, IL1B | 4 | 72 | 121 | 13528 | 6.21120293847566 | 0.0256846778754857 | 1 | 0.130945493487061 | 35.6275690431684
[NAME]~regulation of smooth muscle cell apoptosis | IFNG, IGF1 | 2 | 72 | 5 | 13528 | 75.1555555555555 | 0.0259716560110875 | 1 | 0.131947423657709 | 35.9477897907224
GO:0002360~T cell lineage commitment | BCL2, TP53 | 2 | 72 | 5 | 13528 | 75.1555555555555 | 0.0259716560110875 | 1 | 0.131947423657709 | 35.9477897907224
GO:0002326~B cell lineage commitment | BCL2, TP53 | 2 | 72 | 5 | 13528 | 75.1555555555555 | 0.0259716560110875 | 1 | 0.131947423657709 | 35.9477897907224
GO:0009404~[NAME] process | CYP1B1, CYP1A1 | 2 | 72 | 5 | 13528 | 75.1555555555555 | 0.0259716560110875 | 1 | 0.131947423657709 | 35.9477897907224
GO:0042108~positive regulation of cytokine biosynthetic process | TNF, IFNG, IL1B | 3 | 72 | 48 | 13528 | 11.7430555555555 | 0.0262272077106459 | 1 | 0.132792459583933 | 36.2316815680343
GO:0000077~DNA damage checkpoint | CCND1, TP53, BRCA1 | 3 | 72 | 48 | 13528 | 11.7430555555555 | 0.0262272077106459 | 1 | 0.132792459583933 | 36.2316815680343
GO:0006955~immune response | IGF1R, [NAME], TNF, CXCL3, BCL2, IFNG, TP53, IL1B, NOS2 | 9 | 72 | 690 | 13528 | 2.45072463768115 | 0.0275916307654947 | 1 | 0.138892910082208 | 37.7274882812639
GO:0006954~inflammatory response | AKT1, FOS, TNF, CXCL3, IL1B, STAT3 | 6 | 72 | 325 | 13528 | 3.46871794871794 | 0.0278298519364726 | 1 | 0.13962536956939 | 37.9852388706315
GO:0016202~regulation of striated muscle tissue development | TBX3, [NAME], CENPF | 3 | 72 | 50 | 13528 | 11.2733333333333 | 0.0282925736545158 | 1 | 0.141407320433535 | 38.4830285881071
GO:0009968~negative regulation of signal transduction | AKT1, CCND1, IL1B, NCOR1, PTEN | 5 | 72 | 221 | 13528 | 4.25087983911513 | 0.0287746220679837 | 1 | 0.143266169325369 | 38.9976096692597
GO:0048634~regulation of muscle development | TBX3, [NAME], CENPF | 3 | 72 | 51 | 13528 | 11.0522875816993 | 0.0293490549970703 | 1 | 0.145540440961208 | 39.6055212084593
GO:0043524~negative regulation of neuron apoptosis | KRAS, [NAME], SOD2 | 3 | 72 | 51 | 13528 | 11.0522875816993 | 0.0293490549970703 | 1 | 0.145540440961208 | 39.6055212084593
GO:0031570~DNA integrity checkpoint | CCND1, TP53, BRCA1 | 3 | 72 | 52 | 13528 | 10.8397435897435 | 0.030421148778017 | 1 | 0.150095611940584 | 40.7248806701894
[NAME]negative regulation of molecular function | AKT1, PIM1, TP53, IL1B, BIRC5, UBE2C | 6 | 72 | 334 | 13528 | 3.375249500998 | 0.0308072868696676 | 1 | 0.151457536876464 | 41.1232388689528
GO:0045410~positive regulation of interleukin-6 biosynthetic process | IFNG, IL1B | 2 | 72 | 6 | 13528 | 62.6296296296296 | 0.0310856109343333 | 1 | 0.152316404291011 | 41.4088073644702
GO:0060395~SMAD protein signal transduction | FOS, JUN | 2 | 72 | 6 | 13528 | 62.6296296296296 | 0.0310856109343333 | 1 | 0.152316404291011 | 41.4088073644702
GO:0014911~positive regulation of smooth muscle cell migration | BCL2, IGF1 | 2 | 72 | 6 | 13528 | 62.6296296296296 | 0.0310856109343333 | 1 | 0.152316404291011 | 41.4088073644702
[NAME]~negative regulation of fatty acid metabolic process | AKT1, BRCA1 | 2 | 72 | 6 | 13528 | 62.6296296296296 | 0.0310856109343333 | 1 | 0.152316404291011 | 41.4088073644702
GO:0042634~regulation of hair cycle | TNF, FST | 2 | 72 | 6 | 13528 | 62.6296296296296 | 0.0310856109343333 | 1 | 0.152316404291011 | 41.4088073644702
GO:0051797~regulation of hair follicle development | TNF, FST | 2 | 72 | 6 | 13528 | 62.6296296296296 | 0.0310856109343333 | 1 | 0.152316404291011 | 41.4088073644702
GO:0002544~chronic inflammatory response | TNF, IL1B | 2 | 72 | 6 | 13528 | 62.6296296296296 | 0.0310856109343333 | 1 | 0.152316404291011 | 41.4088073644702
GO:0002521~[NAME] differentiation | [NAME], TNF, BCL2, TP53 | 4 | 72 | 131 | 13528 | 5.73706530958439 | 0.0314761431169022 | 1 | 0.153681340224041 | 41.8073079418027
GO:0032446~protein modification by small protein conjugation | AKT1, MAP3K1, UBE2C, BRCA1 | 4 | 72 | 132 | 13528 | 5.69360269360269 | 0.0320899810636794 | 1 | 0.156050026279854 | 42.428519938819
GO:0007423~sensory organ development | EGFR, CYP1A1, MAP3K1, [NAME], STAT3 | 5 | 72 | 229 | 13528 | 4.10237748665696 | 0.0321947567719638 | 1 | 0.156100235974726 | 42.5339288665473
GO:0045597~positive regulation of cell differentiation | NRCAM, AKT1, [NAME], [NAME], BCL2 | 5 | 72 | 229 | 13528 | 4.10237748665696 | 0.0321947567719638 | 1 | 0.156100235974726 | 42.5339288665473
GO:0006919~activation of caspase activity | TNF, IFNB1, TP53 | 3 | 72 | 54 | 13528 | 10.4382716049382 | 0.0326114232475631 | 1 | 0.157555652870192 | 42.9513191820524
GO:0032870~cellular response to hormone stimulus | AKT1, IGF1R, FOS, STAT3 | 4 | 72 | 133 | 13528 | 5.65079365079365 | 0.032710098806231 | 1 | 0.157573916197919 | 43.0497475379018
GO:0042391~regulation of membrane potential | JUN, [NAME], MAL, SOD2 | 4 | 72 | 134 | 13528 | 5.60862354892205 | 0.0333364878914054 | 1 | 0.159952297751151 | 43.6708504158209
[NAME]negative regulation of secretion | TNF, FST, IL1B | 3 | 72 | 55 | 13528 | 10.2484848484848 | 0.0337292324587326 | 1 | 0.161272915006166 | 44.0570235841235
GO:0050804~regulation of synaptic transmission | EGFR, TNF, KRAS, PTGS2 | 4 | 72 | 136 | 13528 | 5.52614379084967 | 0.0346080440597752 | 1 | 0.164736040981033 | 44.9121264213188
GO:0009612~response to mechanical stimulus | FOS, TNF, JUN | 3 | 72 | 56 | 13528 | 10.0654761904761 | 0.0348619111307262 | 1 | 0.165418143400021 | 45.1568456744385
GO:0042542~response to hydrogen peroxide | JUN, [NAME], SOD2 | 3 | 72 | 56 | 13528 | 10.0654761904761 | 0.0348619111307262 | 1 | 0.165418143400021 | 45.1568456744385
GO:0009408~response to heat | AKT1, BCL2, IL1B | 3 | 72 | 56 | 13528 | 10.0654761904761 | 0.0348619111307262 | 1 | 0.165418143400021 | 45.1568456744385
GO:0048584~positive regulation of response to stimulus | TNF, IFNB1, TGM2, [NAME], BRCA1 | 5 | 72 | 236 | 13528 | 3.9806967984934 | 0.0353760139026233 | 1 | 0.16723820459059 | 45.6492934991372
GO:0030097~hemopoiesis | [NAME], TNF, BCL2, TP53, SOD2 | 5 | 72 | 236 | 13528 | 3.9806967984934 | 0.0353760139026233 | 1 | 0.16723820459059 | 45.6492934991372
GO:0050665~hydrogen peroxide biosynthetic process | CYP1A1, SOD2 | 2 | 72 | 7 | 13528 | 53.6825396825396 | 0.0361730921953118 | 1 | 0.170279947913096 | 46.4045790195751
GO:0033143~regulation of steroid hormone receptor signaling pathway | NCOA3, IGF1 | 2 | 72 | 7 | 13528 | 53.6825396825396 | 0.0361730921953118 | 1 | 0.170279947913096 | 46.4045790195751
GO:0010893~positive regulation of steroid biosynthetic process | TNF, IFNG | 2 | 72 | 7 | 13528 | 53.6825396825396 | 0.0361730921953118 | 1 | 0.170279947913096 | 46.4045790195751
GO:0046782~regulation of viral transcription | IFNB1, MAP3K1 | 2 | 72 | 7 | 13528 | 53.6825396825396 | 0.0361730921953118 | 1 | 0.170279947913096 | 46.4045790195751
GO:0051968~positive regulation of synaptic transmission, glutamatergic | EGFR, PTGS2 | 2 | 72 | 7 | 13528 | 53.6825396825396 | 0.0361730921953118 | 1 | 0.170279947913096 | 46.4045790195751
GO:0017085~response to insecticide | TYMS, CYP1A1 | 2 | 72 | 7 | 13528 | 53.6825396825396 | 0.0361730921953118 | 1 | 0.170279947913096 | 46.4045790195751
GO:0048525~negative regulation of viral reproduction | TNF, IFNB1 | 2 | 72 | 7 | 13528 | 53.6825396825396 | 0.0361730921953118 | 1 | 0.170279947913096 | 46.4045790195751
GO:0055066~di-, tri-valent inorganic cation homeostasis | BCL2, TGM2, IL1B, HP, SOD2 | 5 | 72 | 239 | 13528 | 3.93072989307298 | 0.0367935857381429 | 1 | 0.172529915880796 | 46.9856903707186
GO:0034754~cellular hormone metabolic process | AFP, CYP1B1, CYP1A1 | 3 | 72 | 59 | 13528 | 9.55367231638418 | 0.038347350571444 | 1 | 0.178785165492772 | 48.4149372449236
GO:0043280~positive regulation of caspase activity | TNF, IFNB1, TP53 | 3 | 72 | 59 | 13528 | 9.55367231638418 | 0.038347350571444 | 1 | 0.178785165492772 | 48.4149372449236
GO:0010952~positive regulation of peptidase activity | TNF, IFNB1, TP53 | 3 | 72 | 59 | 13528 | 9.55367231638418 | 0.038347350571444 | 1 | 0.178785165492772 | 48.4149372449236
GO:0051129~negative regulation of cellular component organization | MAP3K1, CENPF, PTEN, BRCA1 | 4 | 72 | 142 | 13528 | 5.29264475743348 | 0.0385722100721605 | 1 | 0.179286152675354 | 48.6187480257131
GO:0007179~transforming growth factor beta receptor signaling pathway | FOS, MAP3K1, JUN | 3 | 72 | 60 | 13528 | 9.39444444444444 | 0.0395377009742099 | 1 | 0.182944717258223 | 49.4852807648266
GO:0007612~learning | FOS, KRAS, JUN | 3 | 72 | 60 | 13528 | 9.39444444444444 | 0.0395377009742099 | 1 | 0.182944717258223 | 49.4852807648266
GO:0045785~positive regulation of cell adhesion | TNF, TGM2, [NAME] | 3 | 72 | 60 | 13528 | 9.39444444444444 | 0.0395377009742099 | 1 | 0.182944717258223 | 49.4852807648266
GO:0016049~cell growth | FGFR2, FGFR1, BCL2 | 3 | 72 | 61 | 13528 | 9.24043715846994 | 0.0407420249725806 | 1 | 0.187581088085293 | 50.5468983454744
GO:0042359~vitamin D metabolic process | CYP3A4, CYP1A1 | 2 | 72 | 8 | 13528 | 46.9722222222222 | 0.0412342348966353 | 1 | 0.189176621219825 | 50.9747107432343
GO:0010660~regulation of muscle cell apoptosis | IFNG, IGF1 | 2 | 72 | 8 | 13528 | 46.9722222222222 | 0.0412342348966353 | 1 | 0.189176621219825 | 50.9747107432343
GO:0055093~response to hyperoxia | CYP1A1, SOD2 | 2 | 72 | 8 | 13528 | 46.9722222222222 | 0.0412342348966353 | 1 | 0.189176621219825 | 50.9747107432343
GO:0048147~negative regulation of fibroblast proliferation | TP53, SOD2 | 2 | 72 | 8 | 13528 | 46.9722222222222 | 0.0412342348966353 | 1 | 0.189176621219825 | 50.9747107432343
GO:0060341~regulation of cellular localization | TNF, FST, IFNG, IL1B, NOS2 | 5 | 72 | 248 | 13528 | 3.78808243727598 | 0.0412420189850828 | 1 | 0.188727506067318 | 50.981448356579
GO:0022602~ovulation cycle process | PGR, AFP, BCL2 | 3 | 72 | 62 | 13528 | 9.09139784946236 | 0.0419601476808376 | 1 | 0.191254485873096 | 51.5992993054448
GO:0000226~microtubule cytoskeleton organization | STMN1, UBE2C, NCOR1, BRCA1 | 4 | 72 | 147 | 13528 | 5.11262282690854 | 0.0420456062006345 | 1 | 0.191127140786114 | 51.6723347524906
GO:0030003~cellular cation homeostasis | BCL2, TGM2, TP53, IL1B, HP | 5 | 72 | 254 | 13528 | 3.69860017497812 | 0.044371012092041 | 1 | 0.200273500322319 | 53.6203511626888
GO:0031668~cellular response to extracellular stimulus | FOS, JUN, TP53 | 3 | 72 | 64 | 13528 | 8.80729166666666 | 0.0444370966697831 | 1 | 0.20004440042671 | 53.6746159175552
GO:0010817~regulation of hormone levels | AFP, CYP1B1, CYP1A1, TBX3 | 4 | 72 | 151 | 13528 | 4.97718910963944 | 0.0449343583861142 | 1 | 0.201583113267248 | 54.0810260550938
GO:0048754~branching morphogenesis of a tube | TBX3, [NAME], IGF1 | 3 | 72 | 65 | 13528 | 8.67179487179487 | 0.0456955801579061 | 1 | 0.204186806067332 | 54.6966766225344
GO:0046546~development of primary male sexual characteristics | CCND1, TBX3, BCL2 | 3 | 72 | 65 | 13528 | 8.67179487179487 | 0.0456955801579061 | 1 | 0.204186806067332 | 54.6966766225344
GO:0045684~positive regulation of epidermis development | TNF, FST | 2 | 72 | 9 | 13528 | 41.753086419753 | 0.0462691734571555 | 1 | 0.206009741206179 | 55.1554394641892
GO:0051000~positive regulation of nitric-oxide synthase activity | AKT1, KRAS | 2 | 72 | 9 | 13528 | 41.753086419753 | 0.0462691734571555 | 1 | 0.206009741206179 | 55.1554394641892
GO:0032094~response to food | AKT1, CYP1A1 | 2 | 72 | 9 | 13528 | 41.753086419753 | 0.0462691734571555 | 1 | 0.206009741206179 | 55.1554394641892
GO:0043491~protein kinase B signaling cascade | AKT1, RPS6KB2 | 2 | 72 | 9 | 13528 | 41.753086419753 | 0.0462691734571555 | 1 | 0.206009741206179 | 55.1554394641892
GO:0048009~insulin-like growth factor receptor signaling pathway | AKT1, IGF1R | 2 | 72 | 9 | 13528 | 41.753086419753 | 0.0462691734571555 | 1 | 0.206009741206179 | 55.1554394641892
GO:0042640~anagen | AKT1, PTGS2 | 2 | 72 | 9 | 13528 | 41.753086419753 | 0.0462691734571555 | 1 | 0.206009741206179 | 55.1554394641892
GO:0006006~glucose metabolic process | AKT1, ALDOA, TNF, ENO1 | 4 | 72 | 153 | 13528 | 4.91212781408859 | 0.046415088020064 | 1 | 0.206092289770389 | 55.2714432732677
GO:0006886~intracellular protein transport | AKT1, TNF, JUN, IFNG, AKAP12, TP53 | 6 | 72 | 374 | 13528 | 3.01426024955436 | 0.0464313520122313 | 1 | 0.205651594157426 | 55.2843558357532
GO:0043434~response to peptide hormone stimulus | AKT1, IGF1R, [NAME], STAT3 | 4 | 72 | 154 | 13528 | 4.88023088023088 | 0.0471644858787498 | 1 | 0.208094439360859 | 55.8627878757967
GO:0048534~hemopoietic or lymphoid organ development | [NAME], TNF, BCL2, TP53, SOD2 | 5 | 72 | 260 | 13528 | 3.61324786324786 | 0.0476307233853645 | 1 | 0.209452278400397 | 56.2269722343679
GO:0051222~positive regulation of protein transport | TNF, IFNG, IL1B | 3 | 72 | 67 | 13528 | 8.41293532338308 | 0.0482517184627959 | 1 | 0.211417304388521 | 56.7076502365603
GO:0055114~oxidation reduction | CYP3A4, CYP1B1, PTGS2, CYP1A1, FASN, NOS2, CYP19A1, SOD2 | 8 | 72 | 639 | 13528 | 2.35228655885932 | 0.0497313795167312 | 1 | 0.216763939706412 | 57.8330349616647
GO:0006839~mitochondrial transport | HSP90AA1, [NAME], TP53 | 3 | 72 | 69 | 13528 | 8.16908212560386 | 0.0508589722437641 | 1 | 0.220674658941652 | 58.6721037408812
[NAME]~positive regulation of peptidyl-serine phosphorylation | BCL2, IFNG | 2 | 72 | 10 | 13528 | 37.5777777777777 | 0.0512780416187318 | 1 | 0.221785331532423 | 58.9799194243169
GO:0046329~negative regulation of JNK cascade | AKT1, NCOR1 | 2 | 72 | 10 | 13528 | 37.5777777777777 | 0.0512780416187318 | 1 | 0.221785331532423 | 58.9799194243169
GO:0070303~negative regulation of stress-activated protein kinase signaling pathway | AKT1, NCOR1 | 2 | 72 | 10 | 13528 | 37.5777777777777 | 0.0512780416187318 | 1 | 0.221785331532423 | 58.9799194243169
GO:0046685~response to arsenic | CYP1A1, PTEN | 2 | 72 | 10 | 13528 | 37.5777777777777 | 0.0512780416187318 | 1 | 0.221785331532423 | 58.9799194243169
GO:0042523~positive regulation of tyrosine phosphorylation of Stat5 protein | [NAME], IGF1 | 2 | 72 | 10 | 13528 | 37.5777777777777 | 0.0512780416187318 | 1 | 0.221785331532423 | 58.9799194243169
GO:0032891~negative regulation of organic acid transport | AKT1, TNF | 2 | 72 | 10 | 13528 | 37.5777777777777 | 0.0512780416187318 | 1 | 0.221785331532423 | 58.9799194243169
GO:0010829~negative regulation of glucose transport | TNF, IL1B | 2 | 72 | 10 | 13528 | 37.5777777777777 | 0.0512780416187318 | 1 | 0.221785331532423 | 58.9799194243169
[NAME]~protein modification by small protein conjugation or removal | AKT1, MAP3K1, UBE2C, BRCA1 | 4 | 72 | 160 | 13528 | 4.69722222222222 | 0.0517862722063037 | 1 | 0.223236183532216 | 59.3503315567931
GO:0007015~actin filament organization | ALDOA, [NAME], EVL | 3 | 72 | 72 | 13528 | 7.8287037037037 | 0.054862819945936 | 1 | 0.234582190344837 | 61.5262724090553
GO:0046907~intracellular transport | AKT1, HSP90AA1, TNF, JUN, [NAME], IFNG, AKAP12, TP53 | 8 | 72 | 657 | 13528 | 2.28784035176729 | 0.0561780265839626 | 1 | 0.239053795468432 | 62.4226184285678
GO:0046661~male sex differentiation | CCND1, TBX3, BCL2 | 3 | 72 | 73 | 13528 | 7.72146118721461 | 0.0562215806518253 | 1 | 0.238660341960253 | 62.451962765849
GO:0022409~positive regulation of cell-cell adhesion | TNF, IL1B | 2 | 72 | 11 | 13528 | 34.1616161616161 | 0.0562609724527906 | 1 | 0.238253014808209 | 62.4784842260454
GO:0051881~regulation of mitochondrial membrane potential | BCL2, SOD2 | 2 | 72 | 11 | 13528 | 34.1616161616161 | 0.0562609724527906 | 1 | 0.238253014808209 | 62.4784842260454
[NAME]~G1 DNA damage checkpoint | CCND1, TP53 | 2 | 72 | 11 | 13528 | 34.1616161616161 | 0.0562609724527906 | 1 | 0.238253014808209 | 62.4784842260454
GO:0046902~regulation of mitochondrial membrane permeability | BCL2, TP53 | 2 | 72 | 11 | 13528 | 34.1616161616161 | 0.0562609724527906 | 1 | 0.238253014808209 | 62.4784842260454
GO:0030520~estrogen receptor signaling pathway | ESR1, ESR2 | 2 | 72 | 11 | 13528 | 34.1616161616161 | 0.0562609724527906 | 1 | 0.238253014808209 | 62.4784842260454
GO:0002520~immune system development | [NAME], TNF, BCL2, TP53, SOD2 | 5 | 72 | 276 | 13528 | 3.40378421900161 | 0.0569602396183154 | 1 | 0.240342367634973 | 62.946358758817
GO:0043086~negative regulation of catalytic activity | AKT1, TP53, IL1B, BIRC5, UBE2C | 5 | 72 | 277 | 13528 | 3.39149618933012 | 0.0575739451591325 | 1 | 0.242095233079049 | 63.3524561784535
GO:0042035~regulation of cytokine biosynthetic process | TNF, IFNG, IL1B | 3 | 72 | 74 | 13528 | 7.61711711711711 | 0.0575921482546059 | 1 | 0.241604577382902 | 63.3644372258457
GO:0001763~morphogenesis of a branching structure | TBX3, [NAME], IGF1 | 3 | 72 | 74 | 13528 | 7.61711711711711 | 0.0575921482546059 | 1 | 0.241604577382902 | 63.3644372258457
GO:0042113~B cell activation | IFNB1, BCL2, TP53 | 3 | 72 | 76 | 13528 | 7.41666666666666 | 0.0603680759910251 | 1 | 0.251387306310097 | 65.1490031173006
GO:0001542~ovulation from ovarian follicle | PGR, AFP | 2 | 72 | 12 | 13528 | 31.3148148148148 | 0.0612180983667683 | 1 | 0.253951569849806 | 65.6788866203664
GO:0045931~positive regulation of mitotic cell cycle | CYP1A1, BIRC5 | 2 | 72 | 12 | 13528 | 31.3148148148148 | 0.0612180983667683 | 1 | 0.253951569849806 | 65.6788866203664
GO:0031577~spindle checkpoint | CENPF, BIRC5 | 2 | 72 | 12 | 13528 | 31.3148148148148 | 0.0612180983667683 | 1 | 0.253951569849806 | 65.6788866203664
[NAME]negative regulation of calcium ion transport | PTGS2, BCL2 | 2 | 72 | 12 | 13528 | 31.3148148148148 | 0.0612180983667683 | 1 | 0.253951569849806 | 65.6788866203664
GO:0006809~nitric oxide biosynthetic process | AKT1, NOS2 | 2 | 72 | 12 | 13528 | 31.3148148148148 | 0.0612180983667683 | 1 | 0.253951569849806 | 65.6788866203664
GO:0014910~regulation of smooth muscle cell migration | BCL2, IGF1 | 2 | 72 | 12 | 13528 | 31.3148148148148 | 0.0612180983667683 | 1 | 0.253951569849806 | 65.6788866203664
GO:0007096~regulation of exit from mitosis | BIRC5, UBE2C | 2 | 72 | 12 | 13528 | 31.3148148148148 | 0.0612180983667683 | 1 | 0.253951569849806 | 65.6788866203664
GO:0019748~secondary metabolic process | CYP1B1, CYP1A1, BCL2 | 3 | 72 | 79 | 13528 | 7.13502109704641 | 0.0646166268965012 | 1 | 0.265794651386471 | 67.7226476049735
GO:0006633~fatty acid biosynthetic process | PTGS2, FASN, BRCA1 | 3 | 72 | 79 | 13528 | 7.13502109704641 | 0.0646166268965012 | 1 | 0.265794651386471 | 67.7226476049735
GO:0042770~DNA damage response, signal transduction | CCND1, TP53, BRCA1 | 3 | 72 | 80 | 13528 | 7.04583333333333 | 0.0660547759808385 | 1 | 0.27039473758102 | 68.5525387343045
GO:0042100~B cell proliferation | IFNB1, BCL2 | 2 | 72 | 13 | 13528 | 28.9059829059829 | 0.0661495510908001 | 1 | 0.27013166601163 | 68.6065179137915
GO:0046209~nitric oxide metabolic process | AKT1, NOS2 | 2 | 72 | 13 | 13528 | 28.9059829059829 | 0.0661495510908001 | 1 | 0.27013166601163 | 68.6065179137915
GO:0045995~regulation of embryonic development | TNF, IL1B | 2 | 72 | 13 | 13528 | 28.9059829059829 | 0.0661495510908001 | 1 | 0.27013166601163 | 68.6065179137915
GO:0048820~hair follicle maturation | AKT1, PTGS2 | 2 | 72 | 13 | 13528 | 28.9059829059829 | 0.0661495510908001 | 1 | 0.27013166601163 | 68.6065179137915
GO:0033198~response to ATP | IL1B, PTEN | 2 | 72 | 13 | 13528 | 28.9059829059829 | 0.0661495510908001 | 1 | 0.27013166601163 | 68.6065179137915
GO:0042522~regulation of tyrosine phosphorylation of Stat5 protein | [NAME], IGF1 | 2 | 72 | 13 | 13528 | 28.9059829059829 | 0.0661495510908001 | 1 | 0.27013166601163 | 68.6065179137915
GO:0010959~regulation of metal ion transport | AKT1, PTGS2, BCL2 | 3 | 72 | 81 | 13528 | 6.95884773662551 | 0.067503657119568 | 1 | 0.274377812297303 | 69.3682906691226
GO:0010639~negative regulation of organelle organization | MAP3K1, CENPF, BRCA1 | 3 | 72 | 82 | 13528 | 6.87398373983739 | 0.0689631217576585 | 1 | 0.278957776505808 | 70.1698421007704
GO:0000187~activation of MAPK activity | TNF, MAP3K1, IL1B | 3 | 72 | 82 | 13528 | 6.87398373983739 | 0.0689631217576585 | 1 | 0.278957776505808 | 70.1698421007704
GO:0045940~positive regulation of steroid metabolic process | TNF, IFNG | 2 | 72 | 14 | 13528 | 26.8412698412698 | 0.0710554616982795 | 1 | 0.285717455402415 | 71.2846087578322
GO:0009651~response to salt stress | TNF, TP53 | 2 | 72 | 14 | 13528 | 26.8412698412698 | 0.0710554616982795 | 1 | 0.285717455402415 | 71.2846087578322
GO:0033135~regulation of peptidyl-serine phosphorylation | BCL2, IFNG | 2 | 72 | 14 | 13528 | 26.8412698412698 | 0.0710554616982795 | 1 | 0.285717455402415 | 71.2846087578322
GO:0043526~neuroprotection | ESR1, ESR2 | 2 | 72 | 14 | 13528 | 26.8412698412698 | 0.0710554616982795 | 1 | 0.285717455402415 | 71.2846087578322
GO:0045408~regulation of interleukin-6 biosynthetic process | IFNG, IL1B | 2 | 72 | 14 | 13528 | 26.8412698412698 | 0.0710554616982795 | 1 | 0.285717455402415 | 71.2846087578322
GO:0008544~epidermis development | AKT1, PTGS2, BCL2, FST | 4 | 72 | 184 | 13528 | 4.08454106280193 | 0.0723514147679556 | 1 | 0.289622878415732 | 71.9552871814256
GO:0048871~multicellular organismal homeostasis | BCL2, IL1B, STAT3 | 3 | 72 | 85 | 13528 | 6.6313725490196 | 0.0734035494940509 | 1 | 0.292648244010293 | 72.4889157351494
GO:0051303~establishment of chromosome localization | CENPF, BIRC5 | 2 | 72 | 15 | 13528 | 25.0518518518518 | 0.0759359606054625 | 1 | 0.300737683651296 | 73.7344128655972
GO:0001662~behavioral fear response | BCL2, ESR2 | 2 | 72 | 15 | 13528 | 25.0518518518518 | 0.0759359606054625 | 1 | 0.300737683651296 | 73.7344128655972
GO:0050931~pigment cell differentiation | BCL2, SOD2 | 2 | 72 | 15 | 13528 | 25.0518518518518 | 0.0759359606054625 | 1 | 0.300737683651296 | 73.7344128655972
GO:0050000~chromosome localization | CENPF, BIRC5 | 2 | 72 | 15 | 13528 | 25.0518518518518 | 0.0759359606054625 | 1 | 0.300737683651296 | 73.7344128655972
GO:0002209~behavioral defense response | BCL2, ESR2 | 2 | 72 | 15 | 13528 | 25.0518518518518 | 0.0759359606054625 | 1 | 0.300737683651296 | 73.7344128655972
GO:0010165~response to X-ray | CCND1, TP53 | 2 | 72 | 15 | 13528 | 25.0518518518518 | 0.0759359606054625 | 1 | 0.300737683651296 | 73.7344128655972
GO:0051668~localization within membrane | EGFR, MAL | 2 | 72 | 15 | 13528 | 25.0518518518518 | 0.0759359606054625 | 1 | 0.300737683651296 | 73.7344128655972
GO:0042060~wound healing | MAP3K1, IL1B, IGF1, TFPI2 | 4 | 72 | 191 | 13528 | 3.934845840605 | 0.0789468683304864 | 1 | 0.310337316903512 | 75.1461955883647
GO:0019318~hexose metabolic process | AKT1, ALDOA, TNF, ENO1 | 4 | 72 | 192 | 13528 | 3.91435185185185 | 0.0799100830787254 | 1 | 0.312925598928287 | 75.5825472927663
GO:0022612~gland morphogenesis | EGFR, BCL2 | 2 | 72 | 16 | 13528 | 23.4861111111111 | 0.080791177566318 | 1 | 0.315219400984413 | 75.9753751178029
GO:0017144~drug metabolic process | CYP3A4, CYP1A1 | 2 | 72 | 16 | 13528 | 23.4861111111111 | 0.080791177566318 | 1 | 0.315219400984413 | 75.9753751178029
GO:0046579~positive regulation of [NAME] protein signal transduction | KRAS, IGF1 | 2 | 72 | 16 | 13528 | 23.4861111111111 | 0.080791177566318 | 1 | 0.315219400984413 | 75.9753751178029
GO:0045598~regulation of fat cell differentiation | AKT1, SOD2 | 2 | 72 | 16 | 13528 | 23.4861111111111 | 0.080791177566318 | 1 | 0.315219400984413 | 75.9753751178029
GO:0033280~response to vitamin D | PTGS2, IL1B | 2 | 72 | 16 | 13528 | 23.4861111111111 | 0.080791177566318 | 1 | 0.315219400984413 | 75.9753751178029
GO:0001819~positive regulation of cytokine production | TNF, IFNG, IL1B | 3 | 72 | 90 | 13528 | 6.26296296296296 | 0.0810024189878439 | 1 | 0.31526185730375 | 76.0686673715246
GO:0043409~negative regulation of MAPKKK cascade | AKT1, NCOR1 | 2 | 72 | 17 | 13528 | 22.1045751633986 | 0.085621241686978 | 1 | 0.329870978001188 | 78.0252853942382
GO:0051057~positive regulation of small GTPase mediated signal transduction | KRAS, IGF1 | 2 | 72 | 17 | 13528 | 22.1045751633986 | 0.085621241686978 | 1 | 0.329870978001188 | 78.0252853942382
GO:0032890~regulation of organic acid transport | AKT1, TNF | 2 | 72 | 17 | 13528 | 22.1045751633986 | 0.085621241686978 | 1 | 0.329870978001188 | 78.0252853942382
GO:0031575~G1/S transition checkpoint | CCND1, TP53 | 2 | 72 | 17 | 13528 | 22.1045751633986 | 0.085621241686978 | 1 | 0.329870978001188 | 78.0252853942382
GO:0046330~positive regulation of JNK cascade | TNF, IL1B | 2 | 72 | 17 | 13528 | 22.1045751633986 | 0.085621241686978 | 1 | 0.329870978001188 | 78.0252853942382
GO:0007398~ectoderm development | AKT1, PTGS2, BCL2, FST | 4 | 72 | 199 | 13528 | 3.77666108319374 | 0.0867960668694059 | 1 | 0.333024018282229 | 78.4983830295526
GO:0010551~regulation of specific transcription from RNA polymerase II promoter | MAP3K1, TP53, NCOR1 | 3 | 72 | 94 | 13528 | 5.99645390070921 | 0.0872497840526504 | 1 | 0.333812712031415 | 78.6785145404193
GO:0051260~protein homooligomerization | TGM2, SOD2, RAD51 | 3 | 72 | 95 | 13528 | 5.93333333333333 | 0.0888338617160582 | 1 | 0.338248330123697 | 79.2963435783575
GO:0008610~lipid biosynthetic process | PTGS2, CYP1A1, FASN, [NAME], CYP19A1 | 5 | 72 | 323 | 13528 | 2.90849673202614 | 0.089593798719298 | 1 | 0.340000307435565 | 79.5867214144292
GO:0008104~protein localization | EGFR, AKT1, TNF, JUN, IFNG, AKAP12, TP53, CENPF, MAL | 9 | 72 | 882 | 13528 | 1.9172335600907 | 0.0899529777126468 | 1 | 0.340459362500484 | 79.7226288373121
[NAME]~lipid storage | TNF, IL1B | 2 | 72 | 18 | 13528 | 20.8765432098765 | 0.090426281423047 | 1 | 0.341280357261584 | 79.9004193247471
GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB cascade | TNF, TGM2, [NAME] | 3 | 72 | 97 | 13528 | 5.81099656357388 | 0.0920277716400039 | 1 | 0.345676530141773 | 80.4911817184439
GO:0060284~regulation of cell development | NRCAM, TBX3, [NAME], TP53 | 4 | 72 | 205 | 13528 | 3.66612466124661 | 0.0928934068028043 | 1 | 0.347714682348382 | 80.8036584046246
GO:0000724~double-strand break repair via homologous recombination | BRCA1, RAD51 | 2 | 72 | 19 | 13528 | 19.7777777777777 | 0.0952064245745578 | 1 | 0.354266843276668 | 81.6156670790281
GO:0010907~positive regulation of glucose metabolic process | AKT1, IGF1 | 2 | 72 | 19 | 13528 | 19.7777777777777 | 0.0952064245745578 | 1 | 0.354266843276668 | 81.6156670790281
GO:0032755~positive regulation of interleukin-6 production | TNF, IL1B | 2 | 72 | 19 | 13528 | 19.7777777777777 | 0.0952064245745578 | 1 | 0.354266843276668 | 81.6156670790281
GO:0042596~fear response | BCL2, ESR2 | 2 | 72 | 19 | 13528 | 19.7777777777777 | 0.0952064245745578 | 1 | 0.354266843276668 | 81.6156670790281
GO:0051966~regulation of synaptic transmission, glutamatergic | EGFR, PTGS2 | 2 | 72 | 19 | 13528 | 19.7777777777777 | 0.0952064245745578 | 1 | 0.354266843276668 | 81.6156670790281
GO:0000725~recombinational repair | BRCA1, RAD51 | 2 | 72 | 19 | 13528 | 19.7777777777777 | 0.0952064245745578 | 1 | 0.354266843276668 | 81.6156670790281
[NAME] follicle morphogenesis | BCL2, FST | 2 | 72 | 19 | 13528 | 19.7777777777777 | 0.0952064245745578 | 1 | 0.354266843276668 | 81.6156670790281
GO:0008217~regulation of blood pressure | PTGS2, NOS2, SOD2 | 3 | 72 | 100 | 13528 | 5.63666666666666 | 0.0968810736944194 | 1 | 0.35876513126887 | 82.1832782435235
GO:0048872~homeostasis of number of cells | AKT1, BCL2, IFNG | 3 | 72 | 100 | 13528 | 5.63666666666666 | 0.0968810736944194 | 1 | 0.35876513126887 | 82.1832782435235
GO:0010608~posttranscriptional regulation of gene expression | AKT1, TNF, BCL2, PTEN | 4 | 72 | 211 | 13528 | 3.56187467087941 | 0.0991646757538292 | 1 | 0.365088562384634 | 82.9307558310764
GO:0006805~xenobiotic metabolic process | CYP3A4, CYP1A1 | 2 | 72 | 20 | 13528 | 18.7888888888888 | 0.0999617983146771 | 1 | 0.366811160740554 | 83.1846512225384
GO:0048678~response to axon injury | BCL2, SOD2 | 2 | 72 | 20 | 13528 | 18.7888888888888 | 0.0999617983146771 | 1 | 0.366811160740554 | 83.1846512225384
Supplemental Table S1B
Term | Genes | Count | List Total | Pop Hits | Pop Total | Fold Enrichment | PValue | [NAME] | [NAME] | [NAME]
[NAME]negative regulation of apoptosis | EGFR, IL6, TNF, TP53, ESR1, NFKBIA, BIRC5, [NAME], SOD2, EDNRB, KRT18, HMOX1, BCL2, CFL1, [NAME], [NAME] | 16 | 43 | 354 | 13528 | 14.219419261595 | 7.15453473563578e-14 | 1.09892983601866e-10 | 1.09892983601866e-10 | 1.19149135002771e-10
GO:0043069~negative regulation of programmed cell death | EGFR, IL6, TNF, TP53, ESR1, NFKBIA, BIRC5, [NAME], SOD2, EDNRB, KRT18, HMOX1, BCL2, CFL1, [NAME], [NAME] | 16 | 43 | 359 | 13528 | 14.0213772105979 | 8.78405986204334e-14 | 1.34977251597945e-10 | 6.74885702878214e-11 | 1.46338496875841e-10
GO:0060548~negative regulation of cell death | EGFR, IL6, TNF, TP53, ESR1, NFKBIA, BIRC5, [NAME], SOD2, EDNRB, KRT18, HMOX1, BCL2, CFL1, [NAME], [NAME] | 16 | 43 | 360 | 13528 | 13.9824289405684 | 9.14222164812272e-14 | 1.40437772522261e-10 | 4.68125538333197e-11 | 1.5226708782734e-10
GO:0042981~regulation of apoptosis | EGFR, IL6, TNF, PTGS2, TP53, ESR1, NFKBIA, BIRC5, [NAME], SOD2, EDNRB, KRT18, CDKN1B, HMOX1, BCL2, CFL1, [NAME], [NAME], [NAME], TOP2A | 20 | 43 | 804 | 13528 | 7.8259863473331 | 5.03726510865684e-13 | 7.7419948230073e-10 | 1.93549842819606e-10 | 8.39395219998095e-10
GO:0043067~regulation of programmed cell death | EGFR, IL6, TNF, PTGS2, TP53, ESR1, NFKBIA, BIRC5, [NAME], SOD2, EDNRB, KRT18, CDKN1B, HMOX1, BCL2, CFL1, [NAME], [NAME], [NAME], TOP2A | 20 | 43 | 812 | 13528 | 7.74888303356627 | 6.01025187430025e-13 | 9.23851883882775e-10 | 1.84770421185476e-10 | 1.00165431504706e-09
GO:0010941~regulation of cell death | EGFR, IL6, TNF, PTGS2, TP53, ESR1, NFKBIA, BIRC5, [NAME], SOD2, EDNRB, KRT18, CDKN1B, HMOX1, BCL2, CFL1, [NAME], [NAME], [NAME], TOP2A | 20 | 43 | 815 | 13528 | 7.72035953773719 | 6.41872169431545e-13 | 9.86477233233529e-10 | 1.64412816694436e-10 | 1.06955555523313e-09
GO:0006916~anti-apoptosis | TNF, HMOX1, BCL2, [NAME], ESR1, NFKBIA, IL1B, [NAME], BIRC5, [NAME], SOD2 | 11 | 43 | 206 | 13528 | 16.7992774892752 | 5.18672304812499e-10 | 7.97199049551444e-07 | 1.13885617381015e-07 | 8.64332849737081e-07
GO:0042127~regulation of cell proliferation | EGFR, IL6, TNF, ADAM10, PTGS2, TP53, NFKBIA, CD40, SOD2, EDNRB, CCND1, CDKN1B, HMOX1, BCL2, [NAME], [NAME], GPNMB | 17 | 43 | 787 | 13528 | 6.79578026654058 | 5.9196299915793e-10 | 9.09846769814315e-07 | 1.13730891482255e-07 | 9.8646693036386e-07
GO:0010033~response to organic substance | EGFR, IL6, TNF, ADAM10, PTGS2, CYP1A1, ESR1, NFKBIA, HSPA1B, CCND1, HMOX1, BCL2, CFL1, [NAME], [NAME] | 15 | 43 | 721 | 13528 | 6.54517304776957 | 1.72749761577076e-08 | 2.65512860283534e-05 | 2.95017770601813e-06 | 2.87875921989311e-05
GO:0051726~regulation of cell cycle | E2F1, EGFR, CCND1, CDKN1B, TNF, PTGS2, CYP1A1, BCL2, TP53, IL1B, BIRC5 | 11 | 43 | 331 | 13528 | 10.4551394646244 | 4.92951717423461e-08 | 7.57638105822744e-05 | 7.57663937756003e-06 | 8.21470858003436e-05
GO:0048545~response to steroid hormone stimulus | CCND1, IL6, TNF, PTGS2, HMOX1, BCL2, ESR1, [NAME], [NAME] | 9 | 43 | 192 | 13528 | 14.7470930232558 | 1.11124254043448e-07 | 0.000170783402773988 | 1.55269692662107e-05 | 0.000185181000278422
GO:0008285~negative regulation of cell proliferation | IL6, CDKN1B, TNF, PTGS2, HMOX1, BCL2, TP53, IL1B, [NAME], [NAME], SOD2 | 11 | 43 | 361 | 13528 | 9.58629130966952 | 1.11189172681313e-07 | 0.00017088316566749 | 1.42413792455498e-05 | 0.000185289182652592
GO:0009617~response to bacterium | GPX2, IL6, TNF, PTGS2, CYP1A1, CCL20, NFKBIA, IL1B, [NAME] | 9 | 43 | 193 | 13528 | 14.6706832148451 | 1.15668695694545e-07 | 0.000177766993198269 | 1.36755061527216e-05 | 0.000192753995997829
GO:0008219~cell death | E2F1, IL6, TNF, TP53, NFKBIA, BIRC5, SOD2, CDKN1B, KRT18, [NAME], HMOX1, [NAME], IL1B, TOP2A | 14 | 43 | 719 | 13528 | 6.12582074586796 | 1.47586357382389e-07 | 0.000226814521693929 | 1.62027435911538e-05 | 0.000245942541698962
GO:0016265~death | E2F1, IL6, TNF, TP53, NFKBIA, BIRC5, SOD2, CDKN1B, KRT18, [NAME], HMOX1, [NAME], IL1B, TOP2A | 14 | 43 | 724 | 13528 | 6.08351535397661 | 1.59950934442802e-07 | 0.000245814388675214 | 1.63895060895091e-05 | 0.000266547235616698
GO:0012501~programmed cell death | E2F1, IL6, TNF, TP53, NFKBIA, BIRC5, SOD2, CDKN1B, KRT18, [NAME], [NAME], IL1B, TOP2A | 13 | 43 | 611 | 13528 | 6.69371598218703 | 2.05913605588657e-07 | 0.000316439166970994 | 1.97803821412323e-05 | 0.000343140743541692
GO:0042493~response to drug | CCND1, PTGS2, CYP1A1, BCL2, TP53, IL1B, [NAME], DNMT3B, SOD2 | 9 | 43 | 216 | 13528 | 13.1085271317829 | 2.74630062082889e-07 | 0.000422017389064555 | 2.48294837117413e-05 | 0.000457651706509132
GO:0007346~regulation of mitotic cell cycle | EGFR, CCND1, TNF, CYP1A1, BCL2, TP53, IL1B, BIRC5 | 8 | 43 | 152 | 13528 | 16.5581395348837 | 3.81938163746155e-07 | 0.000586866796086882 | 3.26127498487816e-05 | 0.000636472584836234
GO:0042327~positive regulation of phosphorylation | EGFR, EDNRB, CCND1, IL6, TNF, BCL2, IL1B | 7 | 43 | 97 | 13528 | 22.7034284344281 | 4.95108784254187e-07 | 0.000760692916193961 | 4.00509026706741e-05 | 0.00082506258420878
GO:0010562~positive regulation of phosphorus metabolic process | EGFR, EDNRB, CCND1, IL6, TNF, BCL2, IL1B | 7 | 43 | 100 | 13528 | 22.0223255813953 | 5.9317438659194e-07 | 0.000911293821969194 | 4.55844261294524e-05 | 0.000988480980190775
GO:0045937~positive regulation of phosphate metabolic process | EGFR, EDNRB, CCND1, IL6, TNF, BCL2, IL1B | 7 | 43 | 100 | 13528 | 22.0223255813953 | 5.9317438659194e-07 | 0.000911293821969194 | 4.55844261294524e-05 | 0.000988480980190775
GO:0051240~positive regulation of multicellular organismal process | EGFR, IL6, TNF, PTGS2, HMOX1, [NAME], [NAME], [NAME], CD40 | 9 | 43 | 244 | 13528 | 11.604269919939 | 6.94071054576239e-07 | 0.0010662187655942 | 5.07981183595074e-05 | 0.00115661685623491
GO:0043627~response to estrogen stimulus | CCND1, PTGS2, HMOX1, BCL2, ESR1, [NAME], [NAME] | 7 | 43 | 105 | 13528 | 20.9736434108527 | 7.91712558299522e-07 | 0.00121612260662029 | 5.5310410495335e-05 | 0.00131932801954448
GO:0045787~positive regulation of cell cycle | EGFR, CCND1, TNF, CYP1A1, IL1B, BIRC5 | 6 | 43 | 57 | 13528 | 33.1162790697674 | 8.38420064626248e-07 | 0.00128782222382839 | 5.6026786071528e-05 | 0.00139716197139483
GO:0010604~positive regulation of macromolecule metabolic process | E2F1, IL6, TNF, TP53, ESR1, NFKBIA, CD40, EDNRB, CCND1, BCL2, HMOX1, IL1B, AREG, DNMT3B | 14 | 43 | 857 | 13528 | 5.13939920219261 | 1.10385198314048e-06 | 0.00169518298598558 | 7.06900611113781e-05 | 0.00183947984050414
[NAME]~apoptosis | E2F1, IL6, KRT18, TNF, [NAME], [NAME], TP53, NFKBIA, IL1B, BIRC5, TOP2A, [NAME] | 12 | 43 | 602 | 13528 | 6.2711890597234 | 1.50202743979405e-06 | 0.00230595509992004 | 9.23404527064519e-05 | 0.0025029991530201
GO:0014070~response to organic cyclic substance | CCND1, PTGS2, CYP1A1, HMOX1, [NAME], [NAME], [NAME] | 7 | 43 | 121 | 13528 | 18.2002690755333 | 1.82273808264933e-06 | 0.00279763030456337 | 0.000107746155979193 | 0.00303742814315999
GO:0031667~response to nutrient levels | CCND1, PTGS2, CYP1A1, HMOX1, BCL2, TP53, IL1B, SOD2 | 8 | 43 | 197 | 13528 | 12.7758233974737 | 2.18720697090646e-06 | 0.00335609646676027 | 0.000124501167258261 | 0.00364477217383862
[NAME]~response to inorganic substance | EGFR, CCND1, PTGS2, CYP1A1, HMOX1, BCL2, [NAME], SOD2 | 8 | 43 | 205 | 13528 | 12.2772546795235 | 2.84989652226999e-06 | 0.00437071768672003 | 0.000156426949612487 | 0.00474905656778767
[NAME]~response to endogenous stimulus | CCND1, IL6, TNF, PTGS2, HMOX1, BCL2, [NAME], ESR1, [NAME], [NAME] | 10 | 43 | 405 | 13528 | 7.76801607809359 | 3.28070407976229e-06 | 0.00502975863029031 | 0.000173862485612463 | 0.00546693417308175
GO:0045073~regulation of chemokine biosynthetic process | IL6, TNF, HMOX1, IL1B | 4 | 43 | 10 | 13528 | 125.841860465116 | 3.28919683641776e-06 | 0.00504274629998058 | 0.000168502596906039 | 0.00548108605776809
GO:0051051~negative regulation of transport | TNF, PTGS2, HMOX1, BCL2, NFKBIA, IL1B, [NAME] | 7 | 43 | 135 | 13528 | 16.3128337639965 | 3.45022272199494e-06 | 0.00528896538172862 | 0.000171049932902733 | 0.00574941079779511
GO:0009611~response to wounding | IL6, TNF, CYP1A1, CCL20, HMOX1, CXCL3, BCL2, CXCL2, IL1B, CD40, SOD2 | 11 | 43 | 530 | 13528 | 6.5295304958315 | 3.71346624101988e-06 | 0.00569135075937676 | 0.000178346850872479 | 0.00618806396144311
GO:0008284~positive regulation of cell proliferation | EGFR, CCND1, IL6, CDKN1B, ADAM10, TNF, PTGS2, [NAME], IL1B, CD40 | 10 | 43 | 414 | 13528 | 7.59914616335243 | 3.92626775151964e-06 | 0.00601651323985708 | 0.00018285253440442 | 0.00654266227425592
GO:0051384~response to glucocorticoid stimulus | CCND1, IL6, TNF, PTGS2, [NAME], IL1B | 6 | 43 | 78 | 13528 | 24.2003577817531 | 4.02943591947142e-06 | 0.00617411680978086 | 0.000182137983978258 | 0.00671457443648382
GO:0009991~response to extracellular stimulus | CCND1, PTGS2, CYP1A1, HMOX1, BCL2, TP53, IL1B, SOD2 | 8 | 43 | 220 | 13528 | 11.4401691331923 | 4.54727937744046e-06 | 0.00696481674835303 | 0.000199671042914739 | 0.00757746807195092
GO:0031960~response to corticosteroid stimulus | CCND1, IL6, TNF, PTGS2, [NAME], IL1B | 6 | 43 | 85 | 13528 | 22.2073871409028 | 6.16154987831335e-06 | 0.00942562897781096 | 0.000263030160915667 | 0.0102673166329503
GO:0002237~response to molecule of bacterial origin | IL6, PTGS2, CYP1A1, NFKBIA, IL1B, [NAME] | 6 | 43 | 86 | 13528 | 21.9491617090319 | 6.52698091180025e-06 | 0.00998184971538351 | 0.000271098446193329 | 0.0108762225739855
GO:0032270~positive regulation of cellular protein metabolic process | EDNRB, CCND1, IL6, TNF, BCL2, NFKBIA, IL1B, DNMT3B | 8 | 43 | 233 | 13528 | 10.8018764347739 | 6.63380742498182e-06 | 0.0101443908480023 | 0.000268284948101715 | 0.0110542234879496
[NAME]negative regulation of molecular function | EDNRB, CDKN1B, HMOX1, TP53, NFKBIA, IL1B, [NAME], BIRC5, [NAME] | 9 | 43 | 334 | 13528 | 8.47737083971591 | 7.20368614532701e-06 | 0.0110110353250956 | 0.00028385984482171 | 0.0120037854686172
GO:0001934~positive regulation of protein amino acid phosphorylation | EDNRB, CCND1, IL6, TNF, BCL2, IL1B | 6 | 43 | 89 | 13528 | 21.2093023255813 | 7.72609246564899e-06 | 0.0118048198578524 | 0.000296832186448936 | 0.0128742389856162
GO:0043523~regulation of neuron apoptosis | TNF, BCL2, ESR1, TP53, [NAME], SOD2 | 6 | 43 | 90 | 13528 | 20.9736434108527 | 8.16192216962155e-06 | 0.0124665660051728 | 0.000305926989183857 | 0.0136004297620395
GO:0051247~positive regulation of protein metabolic process | EDNRB, CCND1, IL6, TNF, BCL2, NFKBIA, IL1B, DNMT3B | 8 | 43 | 243 | 13528 | 10.3573547707914 | 8.73465549025211e-06 | 0.0133355077358656 | 0.000319597111314351 | 0.0145547253634914
GO:0006979~response to oxidative stress | EGFR, GPX2, PTGS2, HMOX1, BCL2, [NAME], SOD2 | 7 | 43 | 164 | 13528 | 13.4282473057288 | 1.05882134649216e-05 | 0.0161424613962092 | 0.000378397465262247 | 0.0176430887343759
GO:0048660~regulation of smooth muscle cell proliferation | EGFR, IL6, TNF, PTGS2, [NAME] | 5 | 43 | 46 | 13528 | 34.1961577350859 | 1.19145139260785e-05 | 0.0181460580728178 | 0.000416111515175732 | 0.0198528905346662
GO:0032642~regulation of chemokine production | IL6, TNF, HMOX1, IL1B | 4 | 43 | 15 | 13528 | 83.8945736434108 | 1.23373647140999e-05 | 0.0187839866289115 | 0.000421303372139858 | 0.0205574093511073
GO:0009725~response to hormone stimulus | CCND1, IL6, TNF, PTGS2, HMOX1, BCL2, ESR1, [NAME], [NAME] | 9 | 43 | 367 | 13528 | 7.71510043723465 | 1.43139938953209e-05 | 0.0217605143556988 | 0.000478163166947154 | 0.0238506426149087
GO:0001932~regulation of protein amino acid phosphorylation | EGFR, EDNRB, CCND1, IL6, TNF, BCL2, IL1B | 7 | 43 | 173 | 13528 | 12.7296679661244 | 1.43614355586682e-05 | 0.0218318438847501 | 0.000469542601820638 | 0.0239296832304058
GO:0009628~response to abiotic stimulus | EGFR, CCND1, TNF, BCL2, TP53, IL1B, [NAME], DNMT3B, SOD2 | 9 | 43 | 368 | 13528 | 7.69413549039433 | 1.45989487770939e-05 | 0.0221888718141574 | 0.00046736466904762 | 0.0243253934087528
GO:0051329~interphase of mitotic cell cycle | E2F1, EGFR, CCND1, CDKN1B, BCL2, BIRC5 | 6 | 43 | 103 | 13528 | 18.3264845337547 | 1.57823105359437e-05 | 0.0239657517012625 | 0.000494930598050613 | 0.0262969177077021
[NAME]interphase | E2F1, EGFR, CCND1, CDKN1B, BCL2, BIRC5 | 6 | 43 | 106 | 13528 | 17.8078104431768 | 1.81455309552414e-05 | 0.0275046005251196 | 0.000557643141592789 | 0.0302340206491003
GO:0031401~positive regulation of protein modification process | EDNRB, CCND1, IL6, TNF, BCL2, IL1B, DNMT3B | 7 | 43 | 187 | 13528 | 11.7766446959333 | 2.23317752474638e-05 | 0.0337419247616493 | 0.000672799486863606 | 0.0372079064267283
GO:0050900~[NAME] migration | EDNRB, IL6, TNF, CXCL3, IL1B | 5 | 43 | 57 | 13528 | 27.5968992248062 | 2.8136539091873e-05 | 0.0423246762930671 | 0.000831317129483255 | 0.0468773355143392
GO:0031399~regulation of protein modification process | EGFR, EDNRB, CCND1, IL6, TNF, BCL2, IL1B, DNMT3B | 8 | 43 | 295 | 13528 | 8.53165155695703 | 3.06131931479907e-05 | 0.0459633566930356 | 0.000887402216060095 | 0.051002615736484
GO:0010212~response to ionizing radiation | CCND1, BCL2, TP53, DNMT3B, SOD2 | 5 | 43 | 60 | 13528 | 26.2170542635658 | 3.45009352548607e-05 | 0.0516473500338401 | 0.000981533762971942 | 0.0574779755595167
GO:0045429~positive regulation of nitric oxide biosynthetic process | EGFR, TNF, IL1B, SOD2 | 4 | 43 | 21 | 13528 | 59.9246954595791 | 3.55982135117007e-05 | 0.0532454706035084 | 0.000994331289412286 | 0.0593055129641917
GO:0043065~positive regulation of apoptosis | CDKN1B, TNF, PTGS2, HMOX1, BCL2, TP53, IL1B, [NAME], TOP2A | 9 | 43 | 430 | 13528 | 6.58474851270957 | 4.45662468354879e-05 | 0.0662063977619049 | 0.00122246374931778 | 0.0742407622747687
GO:0010038~response to metal ion | EGFR, CCND1, PTGS2, CYP1A1, BCL2, [NAME] | 6 | 43 | 129 | 13528 | 14.6327744726879 | 4.67625277957808e-05 | 0.0693534187753983 | 0.00126018224614243 | 0.0778981009866841
GO:0043068~positive regulation of programmed cell death | CDKN1B, TNF, PTGS2, HMOX1, BCL2, TP53, IL1B, [NAME], TOP2A | 9 | 43 | 433 | 13528 | 6.53912669853375 | 4.68166087878742e-05 | 0.0694307768362041 | 0.00123989986325379 | 0.0779881573243712
GO:0043271~negative regulation of ion transport | TNF, PTGS2, BCL2, [NAME] | 4 | 43 | 23 | 13528 | 54.7138523761375 | 4.71973517568295e-05 | 0.0699752140278838 | 0.00122880442802464 | 0.078622173071019
GO:0010942~positive regulation of cell death | CDKN1B, TNF, PTGS2, HMOX1, BCL2, TP53, IL1B, [NAME], TOP2A | 9 | 43 | 435 | 13528 | 6.50906174819567 | 4.836910595837e-05 | 0.0716487483487122 | 0.00123831788212958 | 0.0805733623033488
GO:0033273~response to vitamin | CCND1, PTGS2, CYP1A1, [NAME], IL1B | 5 | 43 | 66 | 13528 | 23.8336856941508 | 5.03095406017643e-05 | 0.0744135191957876 | 0.00126686421114241 | 0.083804469036941
[NAME]~response to hypoxia | CYP1A1, HMOX1, BCL2, [NAME], MMP2, SOD2 | 6 | 43 | 134 | 13528 | 14.0867754251995 | 5.60796438389114e-05 | 0.0825863606629891 | 0.00138930546466786 | 0.093411952372413
GO:0014805~smooth muscle adaptation | HMOX1, IL1B, [NAME] | 3 | 43 | 4 | 13528 | 235.953488372093 | 5.62387104361358e-05 | 0.0828106400445305 | 0.00137114370386948 | 0.0936767931643878
GO:0006954~inflammatory response | IL6, TNF, CCL20, HMOX1, CXCL3, CXCL2, IL1B, CD40 | 8 | 43 | 325 | 13528 | 7.744114490161 | 5.66826309076531e-05 | 0.0834362654971698 | 0.00136038123090331 | 0.0944159030468072
GO:0010647~positive regulation of cell communication | EGFR, IL6, TNF, PTGS2, HMOX1, ESR1, [NAME], CD40 | 8 | 43 | 329 | 13528 | 7.64996112249946 | 6.12365873104772e-05 | 0.0898296658722381 | 0.00144700617749271 | 0.101997762048056
GO:0019221~cytokine-mediated signaling pathway | IL6, KRT18, TNF, [NAME], IL1B | 5 | 43 | 70 | 13528 | 22.4717607973421 | 6.34311542558046e-05 | 0.092894734204912 | 0.00147613332505214 | 0.105651292338027
[NAME]~regulation of protein localization | IL6, TNF, BCL2, NFKBIA, IL1B, CD40 | 6 | 43 | 138 | 13528 | 13.6784630940343 | 6.45170441579612e-05 | 0.0944075384703362 | 0.00147899320772293 | 0.107459042937574
GO:0007584~response to nutrient | CCND1, PTGS2, CYP1A1, HMOX1, BCL2, IL1B | 6 | 43 | 140 | 13528 | 13.4830564784053 | 6.90871584921495e-05 | 0.10074679366697 | 0.00156040821939773 | 0.115066868479174
GO:0070482~response to oxygen levels | CYP1A1, HMOX1, BCL2, [NAME], MMP2, SOD2 | 6 | 43 | 141 | 13528 | 13.387431964374 | 7.14639219943503e-05 | 0.104026079568928 | 0.0015906751720679 | 0.119023228623971
GO:0045428~regulation of nitric oxide biosynthetic process | EGFR, TNF, IL1B, SOD2 | 4 | 43 | 27 | 13528 | 46.6080964685615 | 7.72806813886546e-05 | 0.112001297594662 | 0.00169548956292597 | 0.128705183997046
GO:0007610~behavior | EDNRB, IL6, PTGS2, CCL20, CXCL3, BCL2, CXCL2, [NAME], SOD2 | 9 | 43 | 469 | 13528 | 6.03718946794267 | 8.2133233376958e-05 | 0.118600209429008 | 0.00177650414773855 | 0.136781547906195
GO:0032268~regulation of cellular protein metabolic process | EGFR, EDNRB, CCND1, IL6, TNF, BCL2, NFKBIA, IL1B, DNMT3B | 9 | 43 | 474 | 13528 | 5.97350603473653 | 8.84504335563703e-05 | 0.127117503070017 | 0.00188647293938348 | 0.147294684930343
GO:0006928~cell motion | EDNRB, IL6, TNF, PTGS2, [NAME], CXCL3, CFL1, [NAME], [NAME] | 9 | 43 | 475 | 13528 | 5.96093023255813 | 8.97612155982065e-05 | 0.12887446110827 | 0.0018882038713236 | 0.149475968961054
GO:0032496~response to lipopolysaccharide | PTGS2, CYP1A1, NFKBIA, IL1B, [NAME] | 5 | 43 | 77 | 13528 | 20.4288734521292 | 9.21603492850896e-05 | 0.132081084953167 | 0.0019124525025107 | 0.153468272609458
GO:0051098~regulation of binding | IL6, TNF, HMOX1, BCL2, NFKBIA, IL1B | 6 | 43 | 153 | 13528 | 12.3374373005015 | 0.000105202757131903 | 0.149308000603653 | 0.00215374593735062 | 0.175169003706299
GO:0048661~positive regulation of smooth muscle cell proliferation | EGFR, IL6, TNF, PTGS2 | 4 | 43 | 31 | 13528 | 40.5941485371342 | 0.00011773947446681 | 0.165544803608938 | 0.00237843317291031 | 0.19602415797979
GO:0010638~positive regulation of organelle organization | CDKN1B, TNF, CFL1, IL1B, DNMT3B | 5 | 43 | 83 | 13528 | 18.9520874194452 | 0.000123471072197094 | 0.172864502183014 | 0.00246172801490207 | 0.205557455087201
GO:0051173~positive regulation of nitrogen compound metabolic process | E2F1, EGFR, IL6, TNF, TP53, NFKBIA, IL1B, CD40, AREG, SOD2 | 10 | 43 | 644 | 13528 | 4.88516539072656 | 0.000128827809631135 | 0.179647455654147 | 0.00253551218349967 | 0.214466477762775
GO:0042330~taxis | EDNRB, IL6, CCL20, CXCL3, [NAME], IL1B | 6 | 43 | 160 | 13528 | 11.7976744186046 | 0.000129868013759476 | 0.180958151661288 | 0.00252364693868845 | 0.216196399739843
GO:0006935~chemotaxis | EDNRB, IL6, CCL20, CXCL3, [NAME], IL1B | 6 | 43 | 160 | 13528 | 11.7976744186046 | 0.000129868013759476 | 0.180958151661288 | 0.00252364693868845 | 0.216196399739843
GO:0007626~locomotory behavior | EDNRB, IL6, CCL20, CXCL3, CXCL2, [NAME], SOD2 | 7 | 43 | 274 | 13528 | 8.03734510269903 | 0.000185797325822733 | 0.248434580883997 | 0.00356359803650718 | 0.309168710610541
GO:0016477~cell migration | EDNRB, IL6, TNF, CXCL3, CFL1, [NAME], [NAME] | 7 | 43 | 276 | 13528 | 7.97910347152005 | 0.000193274203380294 | 0.257023721593989 | 0.00366107398446435 | 0.321591487703043
GO:0045080~positive regulation of chemokine biosynthetic process | TNF, HMOX1, IL1B | 3 | 43 | 7 | 13528 | 134.830564784053 | 0.000195674256753672 | 0.259759955640984 | 0.00366133895528686 | 0.325578850211316
GO:0043086~negative regulation of catalytic activity | EDNRB, CDKN1B, TP53, IL1B, [NAME], BIRC5, [NAME] | 7 | 43 | 277 | 13528 | 7.95029804382503 | 0.000197100945688561 | 0.261381709210789 | 0.00364363510311072 | 0.327949028933727
GO:0030595~[NAME] chemotaxis | EDNRB, IL6, CXCL3, IL1B | 4 | 43 | 37 | 13528 | 34.0113136392206 | 0.000200903219420222 | 0.265686529991803 | 0.0036696701316351 | 0.334265541895784
GO:0031328~positive regulation of cellular biosynthetic process | E2F1, EGFR, IL6, TNF, HMOX1, TP53, NFKBIA, IL1B, AREG, SOD2 | 10 | 43 | 685 | 13528 | 4.59276863011373 | 0.00020533974446161 | 0.270677745823286 | 0.00370652083085532 | 0.341635226805903
GO:0009891~positive regulation of biosynthetic process | E2F1, EGFR, IL6, TNF, HMOX1, TP53, NFKBIA, IL1B, AREG, SOD2 | 10 | 43 | 695 | 13528 | 4.52668562824159 | 0.000228890166126893 | 0.296610476923489 | 0.00408285696150789 | 0.380747175621709
GO:0060326~cell chemotaxis | EDNRB, IL6, CXCL3, IL1B | 4 | 43 | 39 | 13528 | 32.2671437090041 | 0.000235282548907952 | 0.303489093499459 | 0.00414851845939223 | 0.391360994370293
GO:0001775~cell activation | EGFR, IL6, ADAM10, TNF, BCL2, TP53, CD40 | 7 | 43 | 287 | 13528 | 7.67328417470221 | 0.000238767187631458 | 0.307210436703298 | 0.00416209829624014 | 0.397146389798608
GO:0008217~regulation of blood pressure | EDNRB, PTGS2, HMOX1, [NAME], SOD2 | 5 | 43 | 100 | 13528 | 15.7302325581395 | 0.00025361074952912 | 0.322840989920313 | 0.00437074798752101 | 0.42178697741475
GO:0055093~response to hyperoxia | CYP1A1, [NAME], SOD2 | 3 | 43 | 8 | 13528 | 117.976744186046 | 0.000260385136952455 | 0.329856941449698 | 0.00443750360293837 | 0.433030681591239
GO:0003013~circulatory system process | EDNRB, MTHFR, PTGS2, HMOX1, [NAME], SOD2 | 6 | 43 | 186 | 13528 | 10.1485371342835 | 0.000262167174400377 | 0.331690424580846 | 0.00441882108290137 | 0.435988197535663
GO:0008015~blood circulation | EDNRB, MTHFR, PTGS2, HMOX1, [NAME], SOD2 | 6 | 43 | 186 | 13528 | 10.1485371342835 | 0.000262167174400377 | 0.331690424580846 | 0.00441882108290137 | 0.435988197535663
GO:0002697~regulation of immune effector process | IL6, TNF, HMOX1, IL1B, CD40 | 5 | 43 | 101 | 13528 | 15.5744876813262 | 0.000263477361520997 | 0.333035236999341 | 0.00439269402865771 | 0.43816256566399
GO:0002700~regulation of production of molecular mediator of immune response | IL6, TNF, HMOX1, CD40 | 4 | 43 | 41 | 13528 | 30.6931366988088 | 0.000273258538235642 | 0.342989821215552 | 0.00450654360713842 | 0.45439385862398
GO:0051090~regulation of transcription factor activity | IL6, TNF, HMOX1, NFKBIA, IL1B | 5 | 43 | 103 | 13528 | 15.2720704447956 | 0.000284034806845283 | 0.353785320497062 | 0.00463415994042937 | 0.47227356879862
GO:0051270~regulation of cell motion | EGFR, IL6, CDKN1B, ADAM10, HMOX1, BCL2 | 6 | 43 | 193 | 13528 | 9.78045547656344 | 0.00031097751784243 | 0.380006806778031 | 0.00501943170402796 | 0.516963020365157
GO:0051023~regulation of immunoglobulin secretion | IL6, TNF, CD40 | 3 | 43 | 9 | 13528 | 104.868217054263 | 0.000334121625973433 | 0.401680718206478 | 0.00533603285622741 | 0.555336727768274
GO:0048870~cell motility | EDNRB, IL6, TNF, CXCL3, CFL1, [NAME], [NAME] | 7 | 43 | 307 | 13528 | 7.1733959548519 | 0.000342842158218801 | 0.409649439325098 | 0.00541865499228 | 0.569792053357554
GO:0051674~localization of cell | EDNRB, IL6, TNF, CXCL3, CFL1, [NAME], [NAME] | 7 | 43 | 307 | 13528 | 7.1733959548519 | 0.000342842158218801 | 0.409649439325098 | 0.00541865499228 | 0.569792053357554
GO:0008283~cell proliferation | E2F1, EGFR, CYP1A1, HMOX1, BCL2, TP53, CD40, AREG | 8 | 43 | 436 | 13528 | 5.77256240665671 | 0.000349569101784947 | 0.415723904102654 | 0.00546847926432647 | 0.580941417705271
GO:0044057~regulation of system process | EGFR, EDNRB, TNF, PTGS2, HMOX1, IL1B, [NAME] | 7 | 43 | 309 | 13528 | 7.12696620757131 | 0.000354945785119256 | 0.42053413100943 | 0.00549644015732708 | 0.589851989998124
GO:0007568~aging | BCL2, TP53, IL1B, [NAME], SOD2 | 5 | 43 | 110 | 13528 | 14.3002114164904 | 0.0003651095385786 | 0.429519237466939 | 0.00559703620674567 | 0.606693940326086
GO:0009314~response to radiation | EGFR, CCND1, BCL2, TP53, DNMT3B, SOD2 | 6 | 43 | 200 | 13528 | 9.43813953488372 | 0.000366404757431565 | 0.430654207857123 | 0.00556138200218503 | 0.608840003121868
GO:0044093~positive regulation of molecular function | EGFR, EDNRB, CCND1, IL6, TNF, BCL2, TP53, IL1B, [NAME] | 9 | 43 | 586 | 13528 | 4.83181204857528 | 0.000378236948181668 | 0.440918578694719 | 0.0056843722841775 | 0.628442877754309
GO:0033209~tumor necrosis factor-mediated signaling pathway | KRT18, TNF, KRT8 | 3 | 43 | 10 | 13528 | 94.3813953488372 | 0.000416829733251554 | 0.473129695219181 | 0.00620205495320413 | 0.69235586866293
GO:0051223~regulation of protein transport | IL6, TNF, NFKBIA, IL1B, CD40 | 5 | 43 | 114 | 13528 | 13.7984496124031 | 0.000418240961156924 | 0.47427174490755 | 0.00616333999498286 | 0.694692251688278
GO:0001503~ossification | EGFR, PTGS2, [NAME], GPNMB, MMP2 | 5 | 43 | 115 | 13528 | 13.6784630940343 | 0.000432342544374744 | 0.485548595569491 | 0.00631004731608564 | 0.718035536754635
GO:0042325~regulation of phosphorylation | EGFR, EDNRB, CCND1, IL6, CDKN1B, TNF, BCL2, IL1B | 8 | 43 | 466 | 13528 | 5.40093821738696 | 0.000521574348256258 | 0.55151000641511 | 0.00753625993164341 | 0.8656273132564
GO:0006952~defense response | IL6, TNF, CCL20, HMOX1, CXCL3, BCL2, CXCL2, IL1B, CD40 | 9 | 43 | 615 | 13528 | 4.60397050482132 | 0.000522168616070845 | 0.551919679197426 | 0.00747456818908909 | 0.866609556320741
GO:0070201~regulation of establishment of protein localization | IL6, TNF, NFKBIA, IL1B, CD40 | 5 | 43 | 121 | 13528 | 13.0001921968095 | 0.000524184912093797 | 0.553306876309692 | 0.00743411300610907 | 0.869942148497771
GO:0051101~regulation of DNA binding | IL6, TNF, HMOX1, NFKBIA, IL1B | 5 | 43 | 121 | 13528 | 13.0001921968095 | 0.000524184912093797 | 0.553306876309692 | 0.00743411300610907 | 0.869942148497771
GO:0060348~bone development | EGFR, PTGS2, [NAME], GPNMB, MMP2 | 5 | 43 | 123 | 13528 | 12.788806957837 | 0.000557666012404202 | 0.57572427777639 | 0.00783494142157581 | 0.925265285265597
[NAME]negative regulation of calcium ion transport | PTGS2, BCL2, [NAME] | 3 | 43 | 12 | 13528 | 78.6511627906976 | 0.000608946011963709 | 0.607898720952642 | 0.00847511029018976 | 1.00994251063616
GO:0043500~muscle adaptation | HMOX1, IL1B, [NAME] | 3 | 43 | 12 | 13528 | 78.6511627906976 | 0.000608946011963709 | 0.607898720952642 | 0.00847511029018976 | 1.00994251063616
[NAME]~response to iron ion | CCND1, CYP1A1, BCL2 | 3 | 43 | 12 | 13528 | 78.6511627906976 | 0.000608946011963709 | 0.607898720952642 | 0.00847511029018976 | 1.00994251063616
GO:0019220~regulation of phosphate metabolic process | EGFR, EDNRB, CCND1, IL6, CDKN1B, TNF, BCL2, IL1B | 8 | 43 | 485 | 13528 | 5.18935507072644 | 0.000661686905962586 | 0.638447997232018 | 0.00912343643754065 | 1.09696110318351
GO:0051174~regulation of phosphorus metabolic process | EGFR, EDNRB, CCND1, IL6, CDKN1B, TNF, BCL2, IL1B | 8 | 43 | 485 | 13528 | 5.18935507072644 | 0.000661686905962586 | 0.638447997232018 | 0.00912343643754065 | 1.09696110318351
GO:0000082~G1/S transition of mitotic cell cycle | EGFR, CCND1, CDKN1B, BCL2 | 4 | 43 | 56 | 13528 | 22.4717607973421 | 0.000687957740870561 | 0.652765500008857 | 0.00939978371363314 | 1.14027921341441
GO:0032583~regulation of gene-specific transcription | IL6, CDKN1B, TNF, TP53, NFKBIA | 5 | 43 | 134 | 13528 | 11.7389795209996 | 0.000769559873021714 | 0.693724079206281 | 0.0104167717234032 | 1.2747196685736
GO:0009411~response to UV | EGFR, CCND1, BCL2, TP53 | 4 | 43 | 59 | 13528 | 21.3291288923925 | 0.000801613173057291 | 0.708458680858313 | 0.0107538084569307 | 1.3274808248833
GO:0045069~regulation of viral genome replication | TNF, [NAME], TOP2A | 3 | 43 | 14 | 13528 | 67.4152823920265 | 0.000836306722553171 | 0.723609685191417 | 0.011119810366308 | 1.38455807904713
GO:0007005~mitochondrion organization | BCL2, TP53, SYNJ2, [NAME], SOD2 | 5 | 43 | 138 | 13528 | 11.3987192450286 | 0.000859058417849629 | 0.733115754469944 | 0.0113228247518621 | 1.42197194072362
GO:0050931~pigment cell differentiation | EDNRB, BCL2, SOD2 | 3 | 43 | 15 | 13528 | 62.9209302325581 | 0.000963071239138013 | 0.77257931552573 | 0.0125779522228081 | 1.59284520974978
GO:0045765~regulation of angiogenesis | IL6, HMOX1, IL1B, [NAME] | 4 | 43 | 63 | 13528 | 19.9748984865263 | 0.000970800951502092 | 0.775267799988518 | 0.0125715451926431 | 1.60553253561062
GO:0010243~response to organic nitrogen | CCND1, PTGS2, CFL1, [NAME] | 4 | 43 | 63 | 13528 | 19.9748984865263 | 0.000970800951502092 | 0.775267799988518 | 0.0125715451926431 | 1.60553253561062
GO:0060341~regulation of cellular localization | IL6, TNF, HMOX1, NFKBIA, IL1B, CD40 | 6 | 43 | 248 | 13528 | 7.61140285071267 | 0.00097233905493835 | 0.77579896947392 | 0.0124862005394101 | 1.60805695058966
GO:0043085~positive regulation of catalytic activity | EGFR, EDNRB, CCND1, TNF, BCL2, TP53, IL1B, [NAME] | 8 | 43 | 520 | 13528 | 4.84007155635062 | 0.00099741374786712 | 0.78428344303166 | 0.0127002455540151 | 1.64920224940605
GO:0007242~intracellular signaling cascade | EGFR, EDNRB, CCND1, TNF, HMOX1, CFL1, ESR1, TP53, NFKBIA, IL1B, TOP2A, TANK | 12 | 43 | 1256 | 13528 | 3.00577692193749 | 0.00121411356569855 | 0.845448250788366 | 0.015313164880933 | 2.00411376282025
GO:0032535~regulation of cellular component size | CDKN1B, ADAM10, [NAME], [NAME], TP53, ENO1 | 6 | 43 | 271 | 13528 | 6.96541663091049 | 0.00144262565538391 | 0.891273154910672 | 0.0180234400105528 | 2.37706712524016
GO:0032101~regulation of response to external stimulus | GPX2, IL6, ADAM10, PTGS2, [NAME] | 5 | 43 | 159 | 13528 | 9.89322802398713 | 0.00145283110723106 | 0.89296774823399 | 0.0180036460423506 | 2.3936922245172
GO:0042035~regulation of cytokine biosynthetic process | IL6, TNF, HMOX1, IL1B | 4 | 43 | 74 | 13528 | 17.0056568196103 | 0.00154764804410884 | 0.907502870512692 | 0.0190150950991683 | 2.54802572621634
GO:0032755~positive regulation of interleukin-6 production | IL6, TNF, IL1B | 3 | 43 | 19 | 13528 | 49.6744186046511 | 0.0015561324555666 | 0.908703102822253 | 0.018966928361162 | 2.56182461328942
GO:0051094~positive regulation of developmental process | IL6, TNF, BCL2, [NAME], [NAME], DNMT3B | 6 | 43 | 278 | 13528 | 6.79002844236238 | 0.00161441424967787 | 0.916537665047825 | 0.0195162483514328 | 2.65656339706688
GO:0051241~negative regulation of multicellular organismal process | IL6, TNF, PTGS2, HMOX1, [NAME] | 5 | 43 | 164 | 13528 | 9.59160521837776 | 0.0016279884811007 | 0.918263719017654 | 0.0195254221447493 | 2.67861627736019
GO:0033554~cellular response to stress | CCND1, XRCC3, TNF, HMOX1, BCL2, TP53, TOP2A, [NAME] | 8 | 43 | 566 | 13528 | 4.44670885035746 | 0.0016297548211554 | 0.918485682071608 | 0.0193951998297623 | 2.68148555201599
GO:0002685~regulation of leukocyte migration | IL6, ADAM10, HMOX1 | 3 | 43 | 20 | 13528 | 47.1906976744186 | 0.00172563841851245 | 0.929672849537208 | 0.0203679862439606 | 2.83712133669209
GO:0010740~positive regulation of protein kinase cascade | IL6, TNF, HMOX1, IL1B, CD40 | 5 | 43 | 167 | 13528 | 9.41930093301768 | 0.00173987175084133 | 0.93119727660402 | 0.0203780562850577 | 2.86020456214852
GO:0003012~muscle system process | ALDOA, EDNRB, HMOX1, IL1B, [NAME] | 5 | 43 | 168 | 13528 | 9.36323366555924 | 0.00177832604710479 | 0.935152722940519 | 0.0206668141448234 | 2.92254290430089
GO:0030334~regulation of cell migration | EGFR, IL6, ADAM10, HMOX1, BCL2 | 5 | 43 | 169 | 13528 | 9.30782991605889 | 0.00181736814776514 | 0.93893620521261 | 0.0209578437491244 | 2.98579566516017
GO:0055080~cation homeostasis | EDNRB, HMOX1, BCL2, TP53, IL1B, SOD2 | 6 | 43 | 286 | 13528 | 6.60009757684176 | 0.00182873342141335 | 0.939995545310673 | 0.0209307522673648 | 3.00420145380421
GO:0034097~response to cytokine stimulus | ADAM10, PTGS2, BCL2, [NAME] | 4 | 43 | 79 | 13528 | 15.929349425964 | 0.00186778526937945 | 0.943497495136479 | 0.0212155244813905 | 3.06741997343472
GO:0001836~release of cytochrome c from mitochondria | BCL2, TP53, SOD2 | 3 | 43 | 21 | 13528 | 44.9435215946843 | 0.00190353738749668 | 0.94652414996688 | 0.0214591825688977 | 3.12526281080647
GO:0050792~regulation of viral reproduction | TNF, [NAME], TOP2A | 3 | 43 | 21 | 13528 | 44.9435215946843 | 0.00190353738749668 | 0.94652414996688 | 0.0214591825688977 | 3.12526281080647
GO:0042592~homeostatic process | GPX2, ALDOA, EDNRB, IL6, HMOX1, BCL2, TP53, IL1B, SOD2 | 9 | 43 | 751 | 13528 | 3.77022884216393 | 0.00190701283395466 | 0.946809585976638 | 0.0213416007998588 | 3.13088395497661
GO:0045786~negative regulation of cell cycle | EGFR, CDKN1B, BCL2, TP53 | 4 | 43 | 81 | 13528 | 15.5360321561871 | 0.0020065454367678 | 0.954368574092482 | 0.0222820103166957 | 3.29173669677156
GO:0050865~regulation of cell activation | IL6, HMOX1, IL1B, [NAME], CD40 | 5 | 43 | 175 | 13528 | 8.98870431893687 | 0.00206422812477525 | 0.958247575129334 | 0.0227516634054478 | 3.38484163954266
GO:0043525~positive regulation of neuron apoptosis | TNF, TP53, NQO1 | 3 | 43 | 22 | 13528 | 42.9006342494714 | 0.00208977812823334 | 0.959858711595869 | 0.0228665192842887 | 3.42605466551244
GO:0009967~positive regulation of signal transduction | IL6, TNF, HMOX1, ESR1, [NAME], CD40 | 6 | 43 | 295 | 13528 | 6.39873866771777 | 0.00209410328967346 | 0.960125232451623 | 0.0227515576244923 | 3.43302966255352
GO:0010332~response to gamma radiation | BCL2, TP53, SOD2 | 3 | 43 | 23 | 13528 | 41.0353892821031 | 0.00228430963080475 | 0.970252200230505 | 0.024620915343544 | 3.73929915281163
GO:0051130~positive regulation of cellular component organization | CDKN1B, TNF, CFL1, IL1B, DNMT3B | 5 | 43 | 181 | 13528 | 8.69073621996659 | 0.00233343118495071 | 0.972420282746136 | 0.0249694169614534 | 3.81824600192394
GO:0001817~regulation of cytokine production | IL6, TNF, HMOX1, IL1B, CD40 | 5 | 43 | 181 | 13528 | 8.69073621996659 | 0.00233343118495071 | 0.972420282746136 | 0.0249694169614534 | 3.81824600192394
GO:0043193~positive regulation of gene-specific transcription | IL6, TNF, TP53, NFKBIA | 4 | 43 | 87 | 13528 | 14.464581662657 | 0.00246083656980941 | 0.977335767886463 | 0.0261347078348779 | 4.02272498542609
GO:0001101~response to acid | BCL2, [NAME], NOS3 | 3 | 43 | 24 | 13528 | 39.3255813953488 | 0.0024870811082685 | 0.978233978508185 | 0.0262290843929604 | 4.06479530945589
GO:0030335~positive regulation of cell migration | EGFR, IL6, ADAM10, BCL2 | 4 | 43 | 89 | 13528 | 14.1395348837209 | 0.00262525722850683 | 0.982408265737697 | 0.0274796887931384 | 4.28600762765839
GO:0032768~regulation of monooxygenase activity | EGFR, TNF, IL1B | 3 | 43 | 25 | 13528 | 37.7525581395348 | 0.00269804199632505 | 0.984274864719166 | 0.0280410867256852 | 4.40233912086207
GO:0001819~positive regulation of cytokine production | IL6, TNF, IL1B, CD40 | 4 | 43 | 90 | 13528 | 13.9824289405684 | 0.00270995542648502 | 0.984560953055504 | 0.0279744281817915 | 4.42136762855809
GO:0030308~negative regulation of cell growth | CDKN1B, BCL2, TP53, ENO1 | 4 | 43 | 92 | 13528 | 13.6784630940343 | 0.00288438355847276 | 0.988200563652406 | 0.0295525223835761 | 4.69956241103063
GO:0040012~regulation of locomotion | EGFR, IL6, ADAM10, HMOX1, BCL2 | 5 | 43 | 192 | 13528 | 8.19282945736434 | 0.00288832397629238 | 0.988272015665485 | 0.0293966908993148 | 4.70583816853814
GO:0002637~regulation of immunoglobulin production | IL6, TNF, CD40 | 3 | 43 | 26 | 13528 | 36.3005366726297 | 0.00291714195216677 | 0.988781596103325 | 0.0294910596367615 | 4.75172368314588
GO:0048066~pigmentation during development | EDNRB, BCL2, SOD2 | 3 | 43 | 26 | 13528 | 36.3005366726297 | 0.00291714195216677 | 0.988781596103325 | 0.0294910596367615 | 4.75172368314588
GO:0001558~regulation of cell growth | CDKN1B, ADAM10, [NAME], TP53, ENO1 | 5 | 43 | 194 | 13528 | 8.10836729801007 | 0.00299812138105624 | 0.990098155650207 | 0.0301008099513038 | 4.8805522860263
GO:0055114~oxidation reduction | GPX2, MTHFR, PTGS2, CYP1A1, HMOX1, [NAME], [NAME], SOD2 | 8 | 43 | 639 | 13528 | 3.93871237762492 | 0.00323508721939917 | 0.99312861370853 | 0.0322347386929471 | 5.25659637069536
GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB cascade | TNF, HMOX1, IL1B, CD40 | 4 | 43 | 97 | 13528 | 12.9733876768161 | 0.00335031178648715 | 0.994247234756224 | 0.0331509587072956 | 5.43894231590514
GO:0040017~positive regulation of locomotion | EGFR, IL6, ADAM10, BCL2 | 4 | 43 | 98 | 13528 | 12.8410061699098 | 0.0034487001703499 | 0.995057151086297 | 0.0338916696739731 | 5.59438339422426
GO:0051272~positive regulation of cell motion | EGFR, IL6, ADAM10, BCL2 | 4 | 43 | 98 | 13528 | 12.8410061699098 | 0.0034487001703499 | 0.995057151086297 | 0.0338916696739731 | 5.59438339422426
GO:0051046~regulation of secretion | IL6, TNF, HMOX1, IL1B, CD40 | 5 | 43 | 202 | 13528 | 7.78724384066313 | 0.00346598408321555 | 0.995187174518512 | 0.033842915690768 | 5.62166495379149
GO:0045792~negative regulation of cell size | CDKN1B, BCL2, TP53, ENO1 | 4 | 43 | 99 | 13528 | 12.7112990368804 | 0.00354884664519599 | 0.995764606262042 | 0.0344210693343386 | 5.75235534989703
GO:0043269~regulation of ion transport | TNF, PTGS2, BCL2, [NAME] | 4 | 43 | 99 | 13528 | 12.7112990368804 | 0.00354884664519599 | 0.995764606262042 | 0.0344210693343386 | 5.75235534989703
GO:0010557~positive regulation of macromolecule biosynthetic process | E2F1, IL6, TNF, HMOX1, TP53, NFKBIA, IL1B, AREG | 8 | 43 | 654 | 13528 | 3.84837493777114 | 0.00367932792587027 | 0.996536778815246 | 0.0354429946628022 | 5.9578049476874
GO:0008361~regulation of cell size | CDKN1B, ADAM10, [NAME], TP53, ENO1 | 5 | 43 | 206 | 13528 | 7.63603522239783 | 0.00371761732673003 | 0.996735424108111 | 0.0355832904490939 | 6.01801367063822
GO:0051336~regulation of hydrolase activity | EGFR, EDNRB, TNF, TP53, [NAME], BIRC5 | 6 | 43 | 337 | 13528 | 5.60126975364019 | 0.00371854207949775 | 0.996740078192686 | 0.0353721561774619 | 6.01946736329488
GO:0008637~apoptotic mitochondrial changes | BCL2, TP53, SOD2 | 3 | 43 | 31 | 13528 | 30.4456114028507 | 0.00413298115772966 | 0.998280214112217 | 0.0390037015117559 | 6.66883420504074
GO:0006970~response to osmotic stress | EGFR, TNF, TP53 | 3 | 43 | 32 | 13528 | 29.4941860465116 | 0.00439987062615148 | 0.998860906172407 | 0.0412226608619176 | 7.08477678097602
GO:0043122~regulation of I-kappaB kinase/NF-kappaB cascade | TNF, HMOX1, IL1B, CD40 | 4 | 43 | 107 | 13528 | 11.7609215387959 | 0.00441447517270208 | 0.998886301449804 | 0.041106950425981 | 7.10748735215006
GO:0033043~regulation of organelle organization | CDKN1B, TNF, CFL1, IL1B, DNMT3B | 5 | 43 | 217 | 13528 | 7.24895509591683 | 0.00447322314602952 | 0.998982867069161 | 0.0413935339791395 | 7.19878976755438
GO:0009615~response to virus | IL6, TNF, CYP1A1, BCL2 | 4 | 43 | 109 | 13528 | 11.5451248133134 | 0.00464912850453947 | 0.999224787085751 | 0.0427330723072489 | 7.4716666766104
GO:0045892~negative regulation of transcription, DNA-dependent | E2F1, CDKN1B, TNF, TP53, DNMT3B, ENO1 | 6 | 43 | 356 | 13528 | 5.30232558139534 | 0.00469240659348139 | 0.999274901761612 | 0.04286741423517 | 7.53868702302765
GO:0045926~negative regulation of growth | CDKN1B, BCL2, TP53, ENO1 | 4 | 43 | 110 | 13528 | 11.4401691331923 | 0.00476924118573427 | 0.999356030710799 | 0.0432988497410473 | 7.65756048531863
GO:0006955~immune response | IL6, TNF, CCL20, CXCL3, BCL2, CXCL2, TP53, IL1B | 8 | 43 | 690 | 13528 | 3.64759015840916 | 0.00493654697042699 | 0.999502672857802 | 0.044524810975916 | 7.91590826726014
GO:0050806~positive regulation of synaptic transmission | EGFR, TNF, PTGS2 | 3 | 43 | 34 | 13528 | 27.7592339261285 | 0.00495697937203353 | 0.99951812375949 | 0.0444452657350864 | 7.94741267727452
[NAME]~protein import into nucleus, translocation | TNF, TP53, NFKBIA | 3 | 43 | 34 | 13528 | 27.7592339261285 | 0.00495697937203353 | 0.99951812375949 | 0.0444452657350864 | 7.94741267727452
GO:0051253~negative regulation of RNA metabolic process | E2F1, CDKN1B, TNF, TP53, DNMT3B, ENO1 | 6 | 43 | 362 | 13528 | 5.21444173197995 | 0.0050346122224138 | 0.999572580260122 | 0.0448661686968399 | 8.06702123625979
GO:0010564~regulation of cell cycle process | TNF, CYP1A1, IL1B, BIRC5 | 4 | 43 | 114 | 13528 | 11.0387596899224 | 0.00526846243213862 | 0.999702183489534 | 0.0466364968097985 | 8.4264309345599
GO:0007243~protein kinase cascade | EGFR, TNF, HMOX1, NFKBIA, IL1B, TANK | 6 | 43 | 370 | 13528 | 5.10169704588309 | 0.00551813848170994 | 0.999797519303384 | 0.0485194734293127 | 8.80870561034431
GO:0000278~mitotic cell cycle | E2F1, EGFR, CCND1, CDKN1B, BCL2, BIRC5 | 6 | 43 | 370 | 13528 | 5.10169704588309 | 0.00551813848170994 | 0.999797519303384 | 0.0485194734293127 | 8.80870561034431
GO:0032675~regulation of interleukin-6 production | IL6, TNF, IL1B | 3 | 43 | 36 | 13528 | 26.2170542635658 | 0.00554487160063748 | 0.99980571479551 | 0.0484729011482772 | 8.84954720167721
GO:0048565~gut development | EDNRB, CYP1A1, BCL2 | 3 | 43 | 36 | 13528 | 26.2170542635658 | 0.00554487160063748 | 0.99980571479551 | 0.0484729011482772 | 8.84954720167721
GO:0006974~response to DNA damage stimulus | CCND1, XRCC3, HMOX1, TP53, TOP2A, [NAME] | 6 | 43 | 373 | 13528 | 5.06066462996446 | 0.00570769632243992 | 0.999848944155727 | 0.0495832321879314 | 9.09793204212213
GO:0051971~positive regulation of transmission of nerve impulse | EGFR, TNF, PTGS2 | 3 | 43 | 37 | 13528 | 25.5084852294154 | 0.00585024122233966 | 0.999878819083802 | 0.0505086746516157 | 9.31485810636925
GO:0048584~positive regulation of response to stimulus | IL6, ADAM10, TNF, NFKBIA, IL1B | 5 | 43 | 236 | 13528 | 6.66535277887268 | 0.00601177441226232 | 0.999905601349733 | 0.0515819636695963 | 9.56009253679458
GO:0002684~positive regulation of immune system process | IL6, ADAM10, NFKBIA, IL1B, CD40 | 5 | 43 | 238 | 13528 | 6.60934141098299 | 0.00619184327650618 | 0.999928545435239 | 0.0527963734770652 | 9.83273239398652
GO:0014806~smooth muscle hyperplasia | HMOX1, [NAME] | 2 | 43 | 2 | 13528 | 314.60465116279 | 0.00619993340092105 | 0.999929433908033 | 0.0525730364486848 | 9.84496338954183
GO:0002439~chronic inflammatory response to antigenic stimulus | TNF, IL1B | 2 | 43 | 2 | 13528 | 314.60465116279 | 0.00619993340092105 | 0.999929433908033 | 0.0525730364486848 | 9.84496338954183
GO:0034116~positive regulation of heterotypic cell-cell adhesion | TNF, IL1B | 2 | 43 | 2 | 13528 | 314.60465116279 | 0.00619993340092105 | 0.999929433908033 | 0.0525730364486848 | 9.84496338954183
GO:0055066~di-, tri-valent inorganic cation homeostasis | EDNRB, HMOX1, [NAME], [NAME], SOD2 | 5 | 43 | 239 | 13528 | 6.58168726281988 | 0.00628321533083453 | 0.999937962350392 | 0.0529711002781537 | 9.97078193887119
GO:0010558~negative regulation of macromolecule biosynthetic process | E2F1, IL6, CDKN1B, TNF, TP53, DNMT3B, ENO1 | 7 | 43 | 547 | 13528 | 4.02601930190043 | 0.00646314839414262 | 0.999953034631978 | 0.054154967478327 | 10.2420533170195
GO:0031646~positive regulation of neurological system process | EGFR, TNF, PTGS2 | 3 | 43 | 39 | 13528 | 24.2003577817531 | 0.00648358873968713 | 0.999954496512529 | 0.0540285572056749 | 10.2728210238726
GO:0006357~regulation of transcription from RNA polymerase II promoter | E2F1, IL6, TNF, HMOX1, TP53, NFKBIA, SOD2, ENO1 | 8 | 43 | 727 | 13528 | 3.46194939381337 | 0.00654492051660872 | 0.999958615603063 | 0.0542341511552174 | 10.3650808207369
GO:0051341~regulation of oxidoreductase activity | EGFR, TNF, IL1B | 3 | 43 | 40 | 13528 | 23.5953488372093 | 0.0068114717709186 | 0.999972602267233 | 0.0560858469702864 | 10.76501200755
GO:0051092~positive regulation of NF-kappaB transcription factor activity | IL6, TNF, IL1B | 3 | 43 | 41 | 13528 | 23.0198525241066 | 0.00714676475701295 | 0.999983694654386 | 0.0584619646906918 | 11.2657008989694
GO:0010627~regulation of protein kinase cascade | IL6, TNF, HMOX1, IL1B, CD40 | 5 | 43 | 249 | 13528 | 6.3173624731484 | 0.00724689527702956 | 0.999986036081246 | 0.0589468122462755 | 11.4147117434587
[NAME] regulation of cellular biosynthetic process | E2F1, IL6, CDKN1B, TNF, TP53, DNMT3B, ENO1 | 7 | 43 | 561 | 13528 | 3.92554823197778 | 0.00728861243342412 | 0.999986909482843 | 0.0589663099828643 | 11.4767243608082
[NAME] | BCL2, TP53, CD40 | 3 | 43 | 42 | 13528 | 22.4717607973421 | 0.00748942078935469 | 0.999990407820778 | 0.0602311174027746 | 11.7746557591632
[NAME]~cell cycle process | E2F1, EGFR, CCND1, CDKN1B, BCL2, TP53, BIRC5 | 7 | 43 | 565 | 13528 | 3.89775674006997 | 0.00753798086714217 | 0.999991102714608 | 0.0602968515878037 | 11.8465607643314
GO:0009890~negative regulation of biosynthetic process | E2F1, IL6, CDKN1B, TNF, TP53, DNMT3B, ENO1 | 7 | 43 | 573 | 13528 | 3.84333779780023 | 0.00805530614306953 | 0.999996007693236 | 0.0639843591456298 | 12.6091749461332
GO:0032943~[NAME] cell proliferation | BCL2, TP53, CD40 | 3 | 43 | 44 | 13528 | 21.4503171247357 | 0.00819663539293378 | 0.999996792901823 | 0.0647411835554698 | 12.8164341456071
GO:0070661~leukocyte proliferation | BCL2, TP53, CD40 | 3 | 43 | 44 | 13528 | 21.4503171247357 | 0.00819663539293378 | 0.999996792901823 | 0.0647411835554698 | 12.8164341456071
GO:0050801~ion homeostasis | EDNRB, HMOX1, BCL2, TP53, IL1B, SOD2 | 6 | 43 | 409 | 13528 | 4.61522715642235 | 0.00835663062889436 | 0.999997497221437 | 0.0656318787525588 | 13.0505093530538
GO:0010628~positive regulation of gene expression | E2F1, IL6, TNF, ESR1, TP53, NFKBIA, DNMT3B | 7 | 43 | 581 | 13528 | 3.79041748388904 | 0.00859798776894056 | 0.999998278383054 | 0.0671288608735695 | 13.4025006578998
GO:0030155~regulation of cell adhesion | ADAM10, TNF, BCL2, IL1B | 4 | 43 | 137 | 13528 | 9.18553726022746 | 0.00874364884641402 | 0.999998626414264 | 0.0678882152715487 | 13.6142818221774
GO:0022403~cell cycle phase | E2F1, EGFR, CCND1, CDKN1B, BCL2, BIRC5 | 6 | 43 | 414 | 13528 | 4.55948769801145 | 0.00878238314864857 | 0.999998706484496 | 0.0678387512140477 | 13.6705168269957
GO:0009416~response to light stimulus | EGFR, CCND1, BCL2, TP53 | 4 | 43 | 138 | 13528 | 9.11897539602291 | 0.00891886196711314 | 0.999998953215998 | 0.0685178841247295 | 13.8683845924748
GO:0007049~cell cycle | E2F1, EGFR, CCND1, CDKN1B, KRT18, [NAME], TP53, BIRC5 | 8 | 43 | 776 | 13528 | 3.24334691920402 | 0.00924652176690859 | 0.999999370296747 | 0.0706042180419757 | 14.3416887247791
GO:0034114~regulation of heterotypic cell-cell adhesion | TNF, IL1B | 2 | 43 | 3 | 13528 | 209.736434108527 | 0.00928581265545646 | 0.999999407533834 | 0.0705460546024165 | 14.3982799125351
GO:0070141~response to UV-A | EGFR, CCND1 | 2 | 43 | 3 | 13528 | 209.736434108527 | 0.00928581265545646 | 0.999999407533834 | 0.0705460546024165 | 14.3982799125351
GO:0030730~sequestering of triglyceride | TNF, IL1B | 2 | 43 | 3 | 13528 | 209.736434108527 | 0.00928581265545646 | 0.999999407533834 | 0.0705460546024165 | 14.3982799125351
GO:0010470~regulation of gastrulation | TNF, IL1B | 2 | 43 | 3 | 13528 | 209.736434108527 | 0.00928581265545646 | 0.999999407533834 | 0.0705460546024165 | 14.3982799125351
GO:0070587~regulation of cell-cell adhesion involved in gastrulation | TNF, IL1B | 2 | 43 | 3 | 13528 | 209.736434108527 | 0.00928581265545646 | 0.999999407533834 | 0.0705460546024165 | 14.3982799125351
GO:0060559~positive regulation of calcidiol 1-monooxygenase activity | TNF, IL1B | 2 | 43 | 3 | 13528 | 209.736434108527 | 0.00928581265545646 | 0.999999407533834 | 0.0705460546024165 | 14.3982799125351
GO:0051346~negative regulation of hydrolase activity | TP53, [NAME], BIRC5 | 3 | 43 | 48 | 13528 | 19.6627906976744 | 0.0096973801135141 | 0.999999687172208 | 0.0732102001930474 | 14.9889576454443
GO:0043410~positive regulation of MAPKKK cascade | IL6, TNF, IL1B | 3 | 43 | 48 | 13528 | 19.6627906976744 | 0.0096973801135141 | 0.999999687172208 | 0.0732102001930474 | 14.9889576454443
GO:0042108~positive regulation of cytokine biosynthetic process | TNF, HMOX1, IL1B | 3 | 43 | 48 | 13528 | 19.6627906976744 | 0.0096973801135141 | 0.999999687172208 | 0.0732102001930474 | 14.9889576454443
GO:0014031~mesenchymal cell development | EDNRB, BCL2, CFL1 | 3 | 43 | 51 | 13528 | 18.5061559507523 | 0.010897024355344 | 0.999999951448972 | 0.0815371213384167 | 16.68889212525
GO:0048762~mesenchymal cell differentiation | EDNRB, BCL2, CFL1 | 3 | 43 | 51 | 13528 | 18.5061559507523 | 0.010897024355344 | 0.999999951448972 | 0.0815371213384167 | 16.68889212525
GO:0060485~mesenchyme development | EDNRB, BCL2, CFL1 | 3 | 43 | 52 | 13528 | 18.1502683363148 | 0.0113107761627468 | 0.999999974478068 | 0.0841090101170478 | 17.2677433562022
GO:0001889~liver development | CCND1, CYP1A1, SOD2 | 3 | 43 | 53 | 13528 | 17.8078104431768 | 0.011731388555287 | 0.999999986729786 | 0.0866980403326693 | 17.8523161662479
GO:0035150~regulation of tube size | EDNRB, [NAME], SOD2 | 3 | 43 | 53 | 13528 | 17.8078104431768 | 0.011731388555287 | 0.999999986729786 | 0.0866980403326693 | 17.8523161662479
GO:0050880~regulation of blood vessel size | EDNRB, [NAME], SOD2 | 3 | 43 | 53 | 13528 | 17.8078104431768 | 0.011731388555287 | 0.999999986729786 | 0.0866980403326693 | 17.8523161662479
[NAME]~regulation of intracellular protein transport | TNF, NFKBIA, IL1B | 3 | 43 | 53 | 13528 | 17.8078104431768 | 0.011731388555287 | 0.999999986729786 | 0.0866980403326693 | 17.8523161662479
GO:0031644~regulation of neurological system process | EGFR, EDNRB, TNF, PTGS2 | 4 | 43 | 153 | 13528 | 8.22495820033439 | 0.011796833225431 | 0.999999988014039 | 0.0867484621094184 | 17.9429222404031
GO:0045935~positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | E2F1, IL6, TNF, TP53, NFKBIA, CD40, AREG | 7 | 43 | 624 | 13528 | 3.52921884317233 | 0.0119779066983881 | 0.999999990956213 | 0.0876111863489985 | 18.1931234614905
GO:0043279~response to alkaloid | HMOX1, [NAME], IL1B | 3 | 43 | 54 | 13528 | 17.4780361757105 | 0.0121588170654966 | 0.999999993174797 | 0.0884637001081668 | 18.4423830337376
GO:0032355~response to estradiol stimulus | PTGS2, [NAME], [NAME] | 3 | 43 | 54 | 13528 | 17.4780361757105 | 0.0121588170654966 | 0.999999993174797 | 0.0884637001081668 | 18.4423830337376
[NAME]~regulation of cyclin-dependent protein kinase activity | EGFR, CCND1, CDKN1B | 3 | 43 | 54 | 13528 | 17.4780361757105 | 0.0121588170654966 | 0.999999993174797 | 0.0884637001081668 | 18.4423830337376
GO:0002437~inflammatory response to antigenic stimulus | TNF, IL1B | 2 | 43 | 4 | 13528 | 157.302325581395 | 0.0123623373039015 | 0.999999995027471 | 0.0894643640099357 | 18.721941275162
[NAME]negative regulation of secretion | TNF, HMOX1, IL1B | 3 | 43 | 55 | 13528 | 17.1602536997885 | 0.0125930174247343 | 0.999999996527435 | 0.0906420260200594 | 19.0377175540107
GO:0050671~positive regulation of lymphocyte proliferation | IL6, IL1B, CD40 | 3 | 43 | 55 | 13528 | 17.1602536997885 | 0.0125930174247343 | 0.999999996527435 | 0.0906420260200594 | 19.0377175540107
GO:0042542~response to hydrogen peroxide | HMOX1, BCL2, SOD2 | 3 | 43 | 56 | 13528 | 16.8538205980066 | 0.0130339455606879 | 0.999999998252143 | 0.0932493153295972 | 19.6380945393756
GO:0032946~positive regulation of mononuclear cell proliferation | IL6, IL1B, CD40 | 3 | 43 | 56 | 13528 | 16.8538205980066 | 0.0130339455606879 | 0.999999998252143 | 0.0932493153295972 | 19.6380945393756
GO:0070665~positive regulation of leukocyte proliferation | IL6, IL1B, CD40 | 3 | 43 | 56 | 13528 | 16.8538205980066 | 0.0130339455606879 | 0.999999998252143 | 0.0932493153295972 | 19.6380945393756
GO:0009408~response to heat | BCL2, [NAME], [NAME] | 3 | 43 | 56 | 13528 | 16.8538205980066 | 0.0130339455606879 | 0.999999998252143 | 0.0932493153295972 | 19.6380945393756
GO:0016481~negative regulation of transcription | E2F1, CDKN1B, TNF, TP53, DNMT3B, ENO1 | 6 | 43 | 459 | 13528 | 4.11247910016719 | 0.0133148810317238 | 0.999999998871569 | 0.094736019214469 | 20.0184368035706
GO:0050708~regulation of protein secretion | IL6, TNF, CD40 | 3 | 43 | 58 | 13528 | 16.2726543704891 | 0.0139358098649235 | 0.999999999571182 | 0.0985059801187403 | 20.853081853253
GO:0046822~regulation of nucleocytoplasmic transport | TNF, NFKBIA, IL1B | 3 | 43 | 58 | 13528 | 16.2726543704891 | 0.0139358098649235 | 0.999999999571182 | 0.0985059801187403 | 20.853081853253
GO:0003018~vascular process in circulatory system | EDNRB, [NAME], SOD2 | 3 | 43 | 58 | 13528 | 16.2726543704891 | 0.0139358098649235 | 0.999999999571182 | 0.0985059801187403 | 20.853081853253
GO:0019725~cellular homeostasis | ALDOA, EDNRB, BCL2, TP53, IL1B, SOD2 | 6 | 43 | 466 | 13528 | 4.05070366304022 | 0.0141399726680917 | 0.999999999688074 | 0.099430999435417 | 21.1257216572365
GO:0043473~pigmentation | EDNRB, BCL2, SOD2 | 3 | 43 | 59 | 13528 | 15.9968466692944 | 0.0143966588717871 | 0.999999999790959 | 0.100697375696201 | 21.4672487840155
GO:0002694~regulation of leukocyte activation | IL6, HMOX1, IL1B, CD40 | 4 | 43 | 166 | 13528 | 7.58083496777808 | 0.0146772597050787 | 0.999999999865052 | 0.102109193671659 | 21.8390042978852
GO:0051091~positive regulation of transcription factor activity | IL6, TNF, IL1B | 3 | 43 | 60 | 13528 | 15.7302325581395 | 0.0148640613327631 | 0.999999999899167 | 0.102886937185612 | 22.0855715714607
GO:0009636~response to toxin | CYP1A1, [NAME], [NAME] | 3 | 43 | 61 | 13528 | 15.472359893252 | 0.0153379741536872 | 0.9999999999518701 | 0.105540644840827 | 22.7078325589228
GO:0002703~regulation of leukocyte mediated immunity | HMOX1, IL1B, CD40 | 3 | 43 | 61 | 13528 | 15.472359893252 | 0.0153379741536872 | 0.9999999999518701 | 0.105540644840827 | 22.7078325589228
GO:0002326~B cell lineage commitment | BCL2, TP53 | 2 | 43 | 5 | 13528 | 125.841860465116 | 0.0154295350141857 | 0.99999999995828 | 0.105671844853719 | 22.8275148359729
GO:0002360~T cell lineage commitment | BCL2, TP53 | 2 | 43 | 5 | 13528 | 125.841860465116 | 0.0154295350141857 | 0.99999999995828 | 0.105671844853719 | 22.8275148359729
GO:0006468~protein amino acid phosphorylation | EGFR, CCND1, ADAM10, TNF, BCL2, [NAME], IL1B | 7 | 43 | 667 | 13528 | 3.30169798821519 | 0.016213307120836 | 0.999999999987732 | 0.110286863423782 | 23.8449055603265
GO:0051271~negative regulation of cell motion | CDKN1B, HMOX1, BCL2 | 3 | 43 | 63 | 13528 | 14.9811738648947 | 0.0163051594674022 | 0.999999999989372 | 0.110396646590464 | 23.9633074585747
GO:0001501~skeletal system development | EGFR, PTGS2, [NAME], GPNMB, MMP2 | 5 | 43 | 319 | 13528 | 4.93110738499671 | 0.0167969188203491 | 0.999999999995072 | 0.113063807334283 | 24.5942703176383
GO:0051235~maintenance of location | TNF, NFKBIA, IL1B | 3 | 43 | 64 | 13528 | 14.7470930232558 | 0.0167983467344849 | 0.999999999995083 | 0.112584610185057 | 24.5960952476529
GO:0045471~response to ethanol | CCND1, BCL2, [NAME] | 3 | 43 | 64 | 13528 | 14.7470930232558 | 0.0167983467344849 | 0.999999999995083 | 0.112584610185057 | 24.5960952476529
GO:0007292~female gamete generation | PTGS2, BCL2, [NAME] | 3 | 43 | 65 | 13528 | 14.5202146690518 | 0.0172978739107131 | 0.999999999997748 | 0.115261641754195 | 25.2319691491117
GO:0051345~positive regulation of hydrolase activity | EGFR, EDNRB, TNF, TP53 | 4 | 43 | 179 | 13528 | 7.03027153436403 | 0.0179236890932949 | 0.999999999999154 | 0.118700024687734 | 26.0214893924923
GO:0051222~positive regulation of protein transport | IL6, TNF, IL1B | 3 | 43 | 67 | 13528 | 14.0867754251995 | 0.018315779640377 | 0.999999999999542 | 0.120641556950774 | 26.512145454374
GO:0006800~oxygen and reactive oxygen species metabolic process | CYP1A1, BCL2, SOD2 | 3 | 43 | 67 | 13528 | 14.0867754251995 | 0.018315779640377 | 0.999999999999542 | 0.120641556950774 | 26.512145454374
GO:0042698~ovulation cycle | EGFR, [NAME], [NAME] | 3 | 43 | 67 | 13528 | 14.0867754251995 | 0.018315779640377 | 0.999999999999542 | 0.120641556950774 | 26.512145454374
GO:0002544~chronic inflammatory response | TNF, IL1B | 2 | 43 | 6 | 13528 | 104.868217054263 | 0.0184874333744107 | 0.99999999999965 | 0.121196783800484 | 26.7259861170465
[NAME]negative regulation of gene expression | E2F1, CDKN1B, TNF, TP53, DNMT3B, ENO1 | 6 | 43 | 504 | 13528 | 3.74529346622369 | 0.0192289331511758 | 0.99999999999989 | 0.12525587073574 | 27.6430197890429
GO:0051924~regulation of calcium ion transport | PTGS2, BCL2, [NAME] | 3 | 43 | 69 | 13528 | 13.6784630940343 | 0.0193585418443191 | 0.99999999999991 | 0.125526467655022 | 27.8021986597549
GO:0043388~positive regulation of DNA binding | IL6, TNF, IL1B | 3 | 43 | 70 | 13528 | 13.4830564784053 | 0.0198891403203083 | 0.999999999999961 | 0.128233993584774 | 28.4504272665834
GO:0032386~regulation of intracellular transport | TNF, NFKBIA, IL1B | 3 | 43 | 71 | 13528 | 13.2931542744841 | 0.0204258287226243 | 0.999999999999983 | 0.130947763882534 | 29.1005276440694
GO:0050678~regulation of epithelial cell proliferation | EGFR, EDNRB, CDKN1B | 3 | 43 | 71 | 13528 | 13.2931542744841 | 0.0204258287226243 | 0.999999999999983 | 0.130947763882534 | 29.1005276440694
GO:0045934~negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | E2F1, CDKN1B, TNF, TP53, DNMT3B, ENO1 | 6 | 43 | 512 | 13528 | 3.68677325581395 | 0.0204368582106041 | 0.999999999999983 | 0.130476563400993 | 29.1138294521098
GO:0048878~chemical homeostasis | EDNRB, HMOX1, BCL2, TP53, IL1B, SOD2 | 6 | 43 | 512 | 13528 | 3.68677325581395 | 0.0204368582106041 | 0.999999999999983 | 0.130476563400993 | 29.1138294521098
GO:0040008~regulation of growth | CDKN1B, ADAM10, [NAME], TP53, ENO1 | 5 | 43 | 341 | 13528 | 4.61297142467435 | 0.0209132822740893 | 0.999999999999992 | 0.132791872896209 | 29.6861734675055
GO:0007015~actin filament organization | ALDOA, [NAME], CFL1 | 3 | 43 | 72 | 13528 | 13.1085271317829 | 0.0209685660443472 | 0.999999999999992 | 0.132580961593085 | 29.7523056903985
GO:0042060~wound healing | IL6, HMOX1, IL1B, CD40 | 4 | 43 | 191 | 13528 | 6.58857908194326 | 0.0212491639169191 | 0.999999999999995 | 0.133705410246621 | 30.087065369384
[NAME]~negative regulation of nitrogen compound metabolic process | E2F1, CDKN1B, TNF, TP53, DNMT3B, ENO1 | 6 | 43 | 519 | 13528 | 3.63704799032127 | 0.0215341761814785 | 0.999999999999997 | 0.134845128659444 | 30.425556001108
GO:0060558~regulation of calcidiol 1-monooxygenase activity | TNF, IL1B | 2 | 43 | 7 | 13528 | 89.8870431893687 | 0.0215360598939151 | 0.999999999999997 | 0.134315850943459 | 30.4277880314039
GO:0051968~positive regulation of synaptic transmission, glutamatergic | EGFR, PTGS2 | 2 | 43 | 7 | 13528 | 89.8870431893687 | 0.0215360598939151 | 0.999999999999997 | 0.134315850943459 | 30.4277880314039
GO:0032722~positive regulation of chemokine production | IL6, TNF | 2 | 43 | 7 | 13528 | 89.8870431893687 | 0.0215360598939151 | 0.999999999999997 | 0.134315850943459 | 30.4277880314039
GO:0032494~response to peptidoglycan | IL6, NFKBIA | 2 | 43 | 7 | 13528 | 89.8870431893687 | 0.0215360598939151 | 0.999999999999997 | 0.134315850943459 | 30.4277880314039
GO:0050665~hydrogen peroxide biosynthetic process | CYP1A1, SOD2 | 2 | 43 | 7 | 13528 | 89.8870431893687 | 0.0215360598939151 | 0.999999999999997 | 0.134315850943459 | 30.4277880314039
GO:0031503~protein complex localization | BIRC5, DNMT3B | 2 | 43 | 7 | 13528 | 89.8870431893687 | 0.0215360598939151 | 0.999999999999997 | 0.134315850943459 | 30.4277880314039
GO:0045859~regulation of protein kinase activity | EGFR, CCND1, CDKN1B, TNF, IL1B | 5 | 43 | 345 | 13528 | 4.55948769801145 | 0.0217230048280459 | 0.999999999999997 | 0.134870942438672 | 30.6489665120754
GO:0000302~response to reactive oxygen species | HMOX1, BCL2, SOD2 | 3 | 43 | 75 | 13528 | 12.5841860465116 | 0.0226326642072601 | 0.999999999999999 | 0.139608668014587 | 31.7158029035552
GO:0007166~cell surface receptor linked signal transduction | EGFR, EDNRB, CCND1, ADAM10, APC2, CCL20, CXCL3, CXCL2, NFKBIA, [NAME], CD40, AREG | 12 | 43 | 1856 | 13528 | 2.03408179631114 | 0.0231507417901315 | 0.999999999999999 | 0.142038390716102 | 32.316482708574
GO:0042113~B cell activation | BCL2, TP53, CD40 | 3 | 43 | 76 | 13528 | 12.4186046511627 | 0.0231991908102521 | 0.999999999999999 | 0.141758551129166 | 32.3724017368879
GO:0050727~regulation of inflammatory response | GPX2, IL6, PTGS2 | 3 | 43 | 76 | 13528 | 12.4186046511627 | 0.0231991908102521 | 0.999999999999999 | 0.141758551129166 | 32.3724017368879
GO:0043549~regulation of kinase activity | EGFR, CCND1, CDKN1B, TNF, IL1B | 5 | 43 | 357 | 13528 | 4.40622760732199 | 0.0242675706075781 | 1 | 0.147278193731176 | 33.5945254139023
GO:0051099~positive regulation of binding | IL6, TNF, IL1B | 3 | 43 | 78 | 13528 | 12.1001788908765 | 0.024349744028988 | 1 | 0.147171150064778 | 33.6876589348486
GO:0045737~positive regulation of cyclin-dependent protein kinase activity | EGFR, CCND1 | 2 | 43 | 8 | 13528 | 78.6511627906976 | 0.0245754420023847 | 1 | 0.147871681275659 | 33.9428286418539
GO:0048147~negative regulation of fibroblast proliferation | TP53, SOD2 | 2 | 43 | 8 | 13528 | 78.6511627906976 | 0.0245754420023847 | 1 | 0.147871681275659 | 33.9428286418539
GO:0010605~negative regulation of macromolecule metabolic process | E2F1, IL6, CDKN1B, TNF, TP53, DNMT3B, ENO1 | 7 | 43 | 734 | 13528 | 3.00031683670236 | 0.0247444526503623 | 1 | 0.148249087232048 | 34.1333041015525
GO:0006959~humoral immune response | IL6, TNF, BCL2 | 3 | 43 | 79 | 13528 | 11.947012069473 | 0.0249336910097885 | 1 | 0.148735990174696 | 34.345963545078
GO:0043281~regulation of caspase activity | TNF, TP53, BIRC5 | 3 | 43 | 79 | 13528 | 11.947012069473 | 0.0249336910097885 | 1 | 0.148735990174696 | 34.345963545078
GO:0042770~DNA damage response, signal transduction | CCND1, HMOX1, TP53 | 3 | 43 | 80 | 13528 | 11.7976744186046 | 0.0255233654489913 | 1 | 0.151435883320523 | 35.0044876721151
GO:0010959~regulation of metal ion transport | PTGS2, BCL2, [NAME] | 3 | 43 | 81 | 13528 | 11.6520241171403 | 0.0261187279819686 | 1 | 0.154138305436857 | 35.6630615103967
GO:0052548~regulation of endopeptidase activity | TNF, TP53, BIRC5 | 3 | 43 | 82 | 13528 | 11.5099262620533 | 0.0267197394174949 | 1 | 0.156842887183057 | 36.3215181325648
GO:0009266~response to temperature stimulus | BCL2, [NAME], [NAME] | 3 | 43 | 83 | 13528 | 11.3712524516671 | 0.0273263607485286 | 1 | 0.15954926898477 | 36.9796935298097
GO:0050670~regulation of lymphocyte proliferation | IL6, IL1B, CD40 | 3 | 43 | 83 | 13528 | 11.3712524516671 | 0.0273263607485286 | 1 | 0.15954926898477 | 36.9796935298097
GO:0045944~positive regulation of transcription from RNA polymerase II promoter | E2F1, IL6, TNF, TP53, NFKBIA | 5 | 43 | 371 | 13528 | 4.23995486742305 | 0.0274578688676975 | 1 | 0.159665433383781 | 37.121532003519
GO:0051044~positive regulation of membrane protein ectodomain proteolysis | TNF, IL1B | 2 | 43 | 9 | 13528 | 69.9121447028423 | 0.0276056070500301 | 1 | 0.159867998109759 | 37.2805175287438
GO:0010574~regulation of vascular endothelial growth factor production | IL6, IL1B | 2 | 43 | 9 | 13528 | 69.9121447028423 | 0.0276056070500301 | 1 | 0.159867998109759 | 37.2805175287438
GO:0051338~regulation of transferase activity | EGFR, CCND1, CDKN1B, TNF, IL1B | 5 | 43 | 372 | 13528 | 4.22855713928482 | 0.0276949760951647 | 1 | 0.159756436152809 | 37.3765067559281
GO:0032944~regulation of mononuclear cell proliferation | IL6, IL1B, CD40 | 3 | 43 | 84 | 13528 | 11.235880398671 | 0.0279385531424464 | 1 | 0.160468237214467 | 37.6374266270917
GO:0070663~regulation of leukocyte proliferation | IL6, IL1B, CD40 | 3 | 43 | 84 | 13528 | 11.235880398671 | 0.0279385531424464 | 1 | 0.160468237214467 | 37.6374266270917
GO:0006873~cellular ion homeostasis | EDNRB, BCL2, TP53, IL1B, SOD2 | 5 | 43 | 374 | 13528 | 4.2059445342619 | 0.0281729035379049 | 1 | 0.161125108049542 | 37.8874980649133
GO:0048871~multicellular organismal homeostasis | GPX2, [NAME], IL1B | 3 | 43 | 85 | 13528 | 11.1036935704514 | 0.0285562779442201 | 1 | 0.162563511168028 | 38.2945593102525
GO:0006796~phosphate metabolic process | EGFR, CCND1, ADAM10, TNF, BCL2, CFL1, SYNJ2, IL1B | 8 | 43 | 973 | 13528 | 2.58667750185233 | 0.02876647425557 | 1 | 0.163079089600834 | 38.5166769294464
GO:0006793~phosphorus metabolic process | EGFR, CCND1, ADAM10, TNF, BCL2, CFL1, SYNJ2, IL1B | 8 | 43 | 973 | 13528 | 2.58667750185233 | 0.02876647425557 | 1 | 0.163079089600834 | 38.5166769294464
GO:0052547~regulation of peptidase activity | TNF, TP53, BIRC5 | 3 | 43 | 86 | 13528 | 10.9745808545159 | 0.0291794966742448 | 1 | 0.164651323449542 | 38.9509364449287
GO:0006606~protein import into nucleus | TNF, TP53, NFKBIA | 3 | 43 | 86 | 13528 | 10.9745808545159 | 0.0291794966742448 | 1 | 0.164651323449542 | 38.9509364449287
GO:0045596~negative regulation of cell differentiation | CCND1, TP53, NFKBIA, SOD2 | 4 | 43 | 216 | 13528 | 5.82601205857019 | 0.0291974725339303 | 1 | 0.164153101652298 | 38.9697709711601
GO:0055082~cellular chemical homeostasis | EDNRB, BCL2, TP53, IL1B, SOD2 | 5 | 43 | 380 | 13528 | 4.13953488372093 | 0.0296364722717127 | 1 | 0.165842370467247 | 39.4280487827964
GO:0051170~nuclear import | TNF, TP53, NFKBIA | 3 | 43 | 88 | 13528 | 10.7251585623678 | 0.0304422628813535 | 1 | 0.169404427379769 | 40.2608185455032
GO:0002690~positive regulation of leukocyte chemotaxis | IL6, ADAM10 | 2 | 43 | 10 | 13528 | 62.9209302325581 | 0.0306265823067214 | 1 | 0.169748906046901 | 40.4497908337738
GO:0010829~negative regulation of glucose transport | TNF, IL1B | 2 | 43 | 10 | 13528 | 62.9209302325581 | 0.0306265823067214 | 1 | 0.169748906046901 | 40.4497908337738
[NAME]~positive regulation of peptidyl-serine phosphorylation | IL6, BCL2 | 2 | 43 | 10 | 13528 | 62.9209302325581 | 0.0306265823067214 | 1 | 0.169748906046901 | 40.4497908337738
GO:0045860~positive regulation of protein kinase activity | EGFR, CCND1, TNF, IL1B | 4 | 43 | 223 | 13528 | 5.64313275628324 | 0.0316698275109062 | 1 | 0.174462729611806 | 41.5088242975162
GO:0051050~positive regulation of transport | IL6, TNF, NFKBIA, IL1B | 4 | 43 | 223 | 13528 | 5.64313275628324 | 0.0316698275109062 | 1 | 0.174462729611806 | 41.5088242975162
GO:0000075~cell cycle checkpoint | CCND1, TP53, BIRC5 | 3 | 43 | 91 | 13528 | 10.3715819064656 | 0.0323766647408031 | 1 | 0.177423697041061 | 42.2162699698958
GO:0030036~actin cytoskeleton organization | ALDOA, EPB41L3, [NAME], CFL1 | 4 | 43 | 226 | 13528 | 5.56822391438567 | 0.032762310689851 | 1 | 0.178743122290039 | 42.5988487080165
GO:0031663~lipopolysaccharide-mediated signaling pathway | NFKBIA, [NAME] | 2 | 43 | 11 | 13528 | 57.2008456659619 | 0.0336383949668755 | 1 | 0.182497391775953 | 43.4591350531361
GO:0002688~regulation of leukocyte chemotaxis | IL6, ADAM10 | 2 | 43 | 11 | 13528 | 57.2008456659619 | 0.0336383949668755 | 1 | 0.182497391775953 | 43.4591350531361
GO:0022409~positive regulation of cell-cell adhesion | TNF, IL1B | 2 | 43 | 11 | 13528 | 57.2008456659619 | 0.0336383949668755 | 1 | 0.182497391775953 | 43.4591350531361
[NAME]~G1 DNA damage checkpoint | CCND1, TP53 | 2 | 43 | 11 | 13528 | 57.2008456659619 | 0.0336383949668755 | 1 | 0.182497391775953 | 43.4591350531361
GO:0046902~regulation of mitochondrial membrane permeability | BCL2, TP53 | 2 | 43 | 11 | 13528 | 57.2008456659619 | 0.0336383949668755 | 1 | 0.182497391775953 | 43.4591350531361
GO:0051881~regulation of mitochondrial membrane potential | BCL2, SOD2 | 2 | 43 | 11 | 13528 | 57.2008456659619 | 0.0336383949668755 | 1 | 0.182497391775953 | 43.4591350531361
GO:0007423~sensory organ development | EGFR, CDKN1B, CYP1A1, BCL2 | 4 | 43 | 229 | 13528 | 5.49527774956839 | 0.033874479211922 | 1 | 0.183040248909941 | 43.6888805162033
GO:0034504~protein localization in nucleus | TNF, TP53, NFKBIA | 3 | 43 | 94 | 13528 | 10.0405739732805 | 0.0343584680852488 | 1 | 0.184802732117815 | 44.15713372897
GO:0033674~positive regulation of kinase activity | EGFR, CCND1, TNF, IL1B | 4 | 43 | 231 | 13528 | 5.44769958723447 | 0.0346268392714008 | 1 | 0.185490719507992 | 44.4151995655572
GO:0016310~phosphorylation | EGFR, CCND1, ADAM10, TNF, BCL2, [NAME], IL1B | 7 | 43 | 800 | 13528 | 2.75279069767441 | 0.0357198144985076 | 1 | 0.190198069042212 | 45.4546703044553
GO:0019932~second-messenger-mediated signaling | EGFR, EDNRB, TNF, TOP2A | 4 | 43 | 235 | 13528 | 5.35497278574962 | 0.0361576889887528 | 1 | 0.191679734541079 | 45.8659601738934
GO:0051251~positive regulation of lymphocyte activation | IL6, IL1B, CD40 | 3 | 43 | 97 | 13528 | 9.73004075761208 | 0.0363866713689722 | 1 | 0.192140967003809 | 46.0798777915711
GO:0030097~hemopoiesis | TNF, BCL2, TP53, SOD2 | 4 | 43 | 236 | 13528 | 5.33228222309814 | 0.0365458338112911 | 1 | 0.192263111579536 | 46.2281005429297
GO:0006809~nitric oxide biosynthetic process | [NAME], [NAME] | 2 | 43 | 12 | 13528 | 52.4341085271317 | 0.0366410721445555 | 1 | 0.192078189145794 | 46.3166096265884
GO:0045909~positive regulation of vasodilation | HMOX1, [NAME] | 2 | 43 | 12 | 13528 | 52.4341085271317 | 0.0366410721445555 | 1 | 0.192078189145794 | 46.3166096265884
GO:0045931~positive regulation of mitotic cell cycle | CYP1A1, BIRC5 | 2 | 43 | 12 | 13528 | 52.4341085271317 | 0.0366410721445555 | 1 | 0.192078189145794 | 46.3166096265884
GO:0007267~cell-cell signaling | IL6, ADAM10, CCL20, IL1B, AREG, [NAME] | 6 | 43 | 600 | 13528 | 3.1460465116279 | 0.0371183410008726 | 1 | 0.193717388499706 | 46.7580972183991
GO:0034613~cellular protein localization | [NAME], KRT18, TNF, TP53, NFKBIA | 5 | 43 | 411 | 13528 | 3.82730719176144 | 0.037917059068691 | 1 | 0.196865434068738 | 47.4893084283651
GO:0051347~positive regulation of transferase activity | EGFR, CCND1, TNF, IL1B | 4 | 43 | 240 | 13528 | 5.24341085271317 | 0.0381200805321795 | 1 | 0.197175830799345 | 47.6736602711868
GO:0048872~homeostasis of number of cells | IL6, HMOX1, BCL2 | 3 | 43 | 100 | 13528 | 9.43813953488372 | 0.0384602867784387 | 1 | 0.198128351188274 | 47.9812183073289
GO:0030029~actin filament-based process | ALDOA, EPB41L3, [NAME], CFL1 | 4 | 43 | 241 | 13528 | 5.22165396120814 | 0.0385190480927953 | 1 | 0.197756960037037 | 48.034168133659
[NAME]~cellular macromolecule localization | [NAME], KRT18, TNF, TP53, NFKBIA | 5 | 43 | 414 | 13528 | 3.79957308167621 | 0.0387828295926774 | 1 | 0.19834424607557 | 48.2712380993724
GO:0045321~[NAME] activation | ADAM10, [NAME], TP53, CD40 | 4 | 43 | 242 | 13528 | 5.20007687872381 | 0.0389201734469664 | 1 | 0.198340047481124 | 48.3942711485802
GO:0051043~regulation of membrane protein ectodomain proteolysis | TNF, IL1B | 2 | 43 | 13 | 13528 | 48.4007155635062 | 0.0396346408760393 | 1 | 0.201003840324203 | 49.0298684007833
GO:0046209~nitric oxide metabolic process | [NAME], [NAME] | 2 | 43 | 13 | 13528 | 48.4007155635062 | 0.0396346408760393 | 1 | 0.201003840324203 | 49.0298684007833
GO:0032770~positive regulation of monooxygenase activity | TNF, IL1B | 2 | 43 | 13 | 13528 | 48.4007155635062 | 0.0396346408760393 | 1 | 0.201003840324203 | 49.0298684007833
GO:0050995~negative regulation of lipid catabolic process | TNF, IL1B | 2 | 43 | 13 | 13528 | 48.4007155635062 | 0.0396346408760393 | 1 | 0.201003840324203 | 49.0298684007833
GO:0045995~regulation of embryonic development | TNF, IL1B | 2 | 43 | 13 | 13528 | 48.4007155635062 | 0.0396346408760393 | 1 | 0.201003840324203 | 49.0298684007833
GO:0042100~B cell proliferation | BCL2, CD40 | 2 | 43 | 13 | 13528 | 48.4007155635062 | 0.0396346408760393 | 1 | 0.201003840324203 | 49.0298684007833
GO:0043406~positive regulation of MAP kinase activity | EGFR, TNF, IL1B | 3 | 43 | 102 | 13528 | 9.25307797537619 | 0.0398674443497808 | 1 | 0.201429759242981 | 49.2353780935503
GO:0001568~blood vessel development | HMOX1, IL1B, [NAME], MMP2 | 4 | 43 | 245 | 13528 | 5.13640246796392 | 0.040136472375808 | 1 | 0.202018576658303 | 49.4718952249026
GO:0006355~regulation of transcription, DNA-dependent | E2F1, IL6, CDKN1B, TNF, HMOX1, ESR1, TP53, NFKBIA, DNMT3B, [NAME], ENO1 | 11 | 43 | 1773 | 13528 | 1.95186190794737 | 0.0413648682806055 | 1 | 0.206969399181092 | 50.5387423289274
[NAME]negative regulation of cell communication | CCND1, PTGS2, NFKBIA, IL1B | 4 | 43 | 248 | 13528 | 5.07426856714178 | 0.0413721035015501 | 1 | 0.206347450353378 | 50.544962837389
GO:0030728~ovulation | PTGS2, [NAME] | 2 | 43 | 14 | 13528 | 44.9435215946843 | 0.0426191281178045 | 1 | 0.211312134082774 | 51.6061800110826
GO:0030318~melanocyte differentiation | EDNRB, BCL2 | 2 | 43 | 14 | 13528 | 44.9435215946843 | 0.0426191281178045 | 1 | 0.211312134082774 | 51.6061800110826
GO:0009651~response to salt stress | TNF, TP53 | 2 | 43 | 14 | 13528 | 44.9435215946843 | 0.0426191281178045 | 1 | 0.211312134082774 | 51.6061800110826
GO:0033135~regulation of peptidyl-serine phosphorylation | IL6, BCL2 | 2 | 43 | 14 | 13528 | 44.9435215946843 | 0.0426191281178045 | 1 | 0.211312134082774 | 51.6061800110826
GO:0001944~vasculature development | HMOX1, IL1B, [NAME], MMP2 | 4 | 43 | 251 | 13528 | 5.01361993884925 | 0.0426269967284751 | 1 | 0.210685527359564 | 51.612807716622
GO:0002696~positive regulation of leukocyte activation | IL6, IL1B, CD40 | 3 | 43 | 106 | 13528 | 8.90390522158841 | 0.0427398704215678 | 1 | 0.210531628217767 | 51.7077870114357
GO:0051789~response to protein stimulus | CCND1, BCL2, [NAME] | 3 | 43 | 107 | 13528 | 8.82069115409693 | 0.0434698779497578 | 1 | 0.21312062324851 | 52.3178439671277
GO:0030003~cellular cation homeostasis | EDNRB, BCL2, TP53, IL1B | 4 | 43 | 254 | 13528 | 4.95440395531953 | 0.0439010783274681 | 1 | 0.214366949168185 | 52.6747810043762
GO:0043408~regulation of MAPKKK cascade | IL6, TNF, IL1B | 3 | 43 | 109 | 13528 | 8.65884360998506 | 0.044943930259598 | 1 | 0.218288337540398 | 53.5276733836985
[NAME]~cytoskeleton organization | ALDOA, EPB41L3, [NAME], [NAME], CFL1 | 5 | 43 | 436 | 13528 | 3.60785150416044 | 0.0454814356995681 | 1 | 0.219966663981283 | 53.9616067632194
GO:0002687~positive regulation of leukocyte migration | IL6, ADAM10 | 2 | 43 | 15 | 13528 | 41.9472868217054 | 0.0455945607532843 | 1 | 0.219787830124197 | 54.0524472479347
GO:0010165~response to X-ray | CCND1, TP53 | 2 | 43 | 15 | 13528 | 41.9472868217054 | 0.0455945607532843 | 1 | 0.219787830124197 | 54.0524472479347
GO:0007565~female pregnancy | PTGS2, [NAME], IL1B | 3 | 43 | 110 | 13528 | 8.58012684989429 | 0.0456879059827632 | 1 | 0.219524514182329 | 54.1272774477113
GO:0050867~positive regulation of cell activation | IL6, IL1B, CD40 | 3 | 43 | 111 | 13528 | 8.50282840980515 | 0.0464364689813467 | 1 | 0.222090344531328 | 54.7232336081368
GO:0048534~hemopoietic or lymphoid organ development | TNF, BCL2, TP53, SOD2 | 4 | 43 | 260 | 13528 | 4.84007155635062 | 0.0465064941454142 | 1 | 0.221721893685352 | 54.7786091615918
GO:0051252~regulation of RNA metabolic process | E2F1, IL6, CDKN1B, TNF, HMOX1, ESR1, TP53, NFKBIA, DNMT3B, [NAME], ENO1 | 11 | 43 | 1813 | 13528 | 1.90879821444605 | 0.0471540438734747 | 1 | 0.223826799853885 | 55.2876805880633
GO:0042742~defense response to bacterium | IL6, TNF, CCL20 | 3 | 43 | 112 | 13528 | 8.42691029900332 | 0.0471895851243962 | 1 | 0.223309051032836 | 55.315464813101
GO:0008406~gonad development | CCND1, BCL2, [NAME] | 3 | 43 | 112 | 13528 | 8.42691029900332 | 0.0471895851243962 | 1 | 0.223309051032836 | 55.315464813101
GO:0003006~reproductive developmental process | CCND1, PTGS2, BCL2, [NAME] | 4 | 43 | 262 | 13528 | 4.80312444523344 | 0.047391840623456 | 1 | 0.223502764635871 | 55.4732684991727
GO:0030282~bone mineralization | PTGS2, GPNMB | 2 | 43 | 16 | 13528 | 39.3255813953488 | 0.0485609655816064 | 1 | 0.227778834830661 | 56.3752254361865
GO:0033280~response to vitamin D | PTGS2, IL1B | 2 | 43 | 16 | 13528 | 39.3255813953488 | 0.0485609655816064 | 1 | 0.227778834830661 | 56.3752254361865
GO:0022612~gland morphogenesis | EGFR, BCL2 | 2 | 43 | 16 | 13528 | 39.3255813953488 | 0.0485609655816064 | 1 | 0.227778834830661 | 56.3752254361865
GO:0051412~response to corticosterone stimulus | CCND1, BCL2 | 2 | 43 | 16 | 13528 | 39.3255813953488 | 0.0485609655816064 | 1 | 0.227778834830661 | 56.3752254361865
GO:0051052~regulation of DNA metabolic process | TP53, CD40, AREG | 3 | 43 | 114 | 13528 | 8.27906976744186 | 0.0487093411204248 | 1 | 0.227730023003464 | 56.488458200928
GO:0000122~negative regulation of transcription from RNA polymerase II promoter | E2F1, TNF, TP53, ENO1 | 4 | 43 | 266 | 13528 | 4.73089700996677 | 0.0491876920892956 | 1 | 0.229062579163268 | 56.8516334742045
[NAME] process | MTHFR, DNMT3B, SOD2 | 3 | 43 | 115 | 13528 | 8.20707785642062 | 0.0494759135046682 | 1 | 0.229593121403655 | 57.069080247368
GO:0035094~response to nicotine | HMOX1, BCL2 | 2 | 43 | 17 | 13528 | 37.0123119015047 | 0.0515183693301813 | 1 | 0.237374149936656 | 58.5807399113446
GO:0031575~G1/S transition checkpoint | CCND1, TP53 | 2 | 43 | 17 | 13528 | 37.0123119015047 | 0.0515183693301813 | 1 | 0.237374149936656 | 58.5807399113446
GO:0046330~positive regulation of JNK cascade | TNF, IL1B | 2 | 43 | 17 | 13528 | 37.0123119015047 | 0.0515183693301813 | 1 | 0.237374149936656 | 58.5807399113446
GO:0043200~response to amino acid stimulus | CFL1, [NAME] | 2 | 43 | 17 | 13528 | 37.0123119015047 | 0.0515183693301813 | 1 | 0.237374149936656 | 58.5807399113446
GO:0002520~immune system development | TNF, BCL2, TP53, SOD2 | 4 | 43 | 276 | 13528 | 4.55948769801145 | 0.0538228065523797 | 1 | 0.246110044388918 | 60.2261781475222
GO:0030593~neutrophil chemotaxis | CXCL3, IL1B | 2 | 43 | 18 | 13528 | 34.9560723514211 | 0.0544667986459573 | 1 | 0.248014746932458 | 60.6749026015263
[NAME]~lipid storage | TNF, IL1B | 2 | 43 | 18 | 13528 | 34.9560723514211 | 0.0544667986459573 | 1 | 0.248014746932458 | 60.6749026015263
GO:0002718~regulation of cytokine production during immune response | TNF, HMOX1 | 2 | 43 | 18 | 13528 | 34.9560723514211 | 0.0544667986459573 | 1 | 0.248014746932458 | 60.6749026015263
GO:0042345~regulation of NF-kappaB import into nucleus | TNF, NFKBIA | 2 | 43 | 18 | 13528 | 34.9560723514211 | 0.0544667986459573 | 1 | 0.248014746932458 | 60.6749026015263
GO:0051966~regulation of synaptic transmission, glutamatergic | EGFR, PTGS2 | 2 | 43 | 19 | 13528 | 33.1162790697674 | 0.0574062800986785 | 1 | 0.259101893448824 | 62.6633277864303
GO:0006281~DNA repair | XRCC3, TP53, TOP2A, [NAME] | 4 | 43 | 284 | 13528 | 4.43105142482803 | 0.0576786250209512 | 1 | 0.259453394359891 | 62.8426919919796
GO:0048608~reproductive structure development | CCND1, BCL2, [NAME] | 3 | 43 | 126 | 13528 | 7.49058693244739 | 0.0581925527447995 | 1 | 0.260758805440403 | 63.1789565282201
GO:0045137~development of primary sexual characteristics | CCND1, BCL2, [NAME] | 3 | 43 | 127 | 13528 | 7.4316059329793 | 0.0590099769785084 | 1 | 0.263248837741533 | 63.7079126880355
GO:0045893~positive regulation of transcription, DNA-dependent | E2F1, IL6, TNF, TP53, NFKBIA | 5 | 43 | 477 | 13528 | 3.29774267466237 | 0.0596068299886655 | 1 | 0.264854249030602 | 64.0896161544424
GO:0048511~rhythmic process | EGFR, [NAME], [NAME] | 3 | 43 | 128 | 13528 | 7.3735465116279 | 0.0598314294507662 | 1 | 0.264996127580855 | 64.2322737943772
GO:0048678~response to axon injury | BCL2, SOD2 | 2 | 43 | 20 | 13528 | 31.460465116279 | 0.0603368401896376 | 1 | 0.266228650274874 | 64.5513470680404
GO:0051385~response to mineralocorticoid stimulus | CCND1, BCL2 | 2 | 43 | 20 | 13528 | 31.460465116279 | 0.0603368401896376 | 1 | 0.266228650274874 | 64.5513470680404
GO:0006805~xenobiotic metabolic process | CYP1A1, [NAME] | 2 | 43 | 20 | 13528 | 31.460465116279 | 0.0603368401896376 | 1 | 0.266228650274874 | 64.5513470680404
GO:0051607~defense response to virus | IL6, BCL2 | 2 | 43 | 20 | 13528 | 31.460465116279 | 0.0603368401896376 | 1 | 0.266228650274874 | 64.5513470680404
GO:0042312~regulation of vasodilation | HMOX1, [NAME] | 2 | 43 | 20 | 13528 | 31.460465116279 | 0.0603368401896376 | 1 | 0.266228650274874 | 64.5513470680404
GO:0051254~positive regulation of RNA metabolic process | E2F1, IL6, TNF, TP53, NFKBIA | 5 | 43 | 481 | 13528 | 3.27031861915582 | 0.0610986775514249 | 1 | 0.26844337197379 | 65.0272541471692
GO:0017038~protein import | TNF, TP53, NFKBIA | 3 | 43 | 131 | 13528 | 7.20468666785016 | 0.0623196419019945 | 1 | 0.272401994418357 | 65.7774643745346
GO:0002521~[NAME] differentiation | TNF, BCL2, TP53 | 3 | 43 | 131 | 13528 | 7.20468666785016 | 0.0623196419019945 | 1 | 0.272401994418357 | 65.7774643745346
GO:0070304~positive regulation of stress-activated protein kinase signaling pathway | TNF, IL1B | 2 | 43 | 21 | 13528 | 29.9623477297895 | 0.0632585053279935 | 1 | 0.275245491279117 | 66.3440235689641
GO:0001659~temperature homeostasis | GPX2, IL1B | 2 | 43 | 21 | 13528 | 29.9623477297895 | 0.0632585053279935 | 1 | 0.275245491279117 | 66.3440235689641
GO:0048609~reproductive process in a multicellular organism | EGFR, PTGS2, CYP1A1, BCL2, [NAME] | 5 | 43 | 487 | 13528 | 3.23002721933049 | 0.0633740512666668 | 1 | 0.274939030186694 | 66.4131374927865
[NAME]~multicellular organism reproduction | EGFR, PTGS2, CYP1A1, BCL2, [NAME] | 5 | 43 | 487 | 13528 | 3.23002721933049 | 0.0633740512666668 | 1 | 0.274939030186694 | 66.4131374927865
GO:0046824~positive regulation of nucleocytoplasmic transport | TNF, IL1B | 2 | 43 | 22 | 13528 | 28.6004228329809 | 0.0661713018626445 | 1 | 0.284745061622156 | 68.0461654529877
GO:0045930~negative regulation of mitotic cell cycle | EGFR, BCL2 | 2 | 43 | 22 | 13528 | 28.6004228329809 | 0.0661713018626445 | 1 | 0.284745061622156 | 68.0461654529877
GO:0022407~regulation of cell-cell adhesion | TNF, IL1B | 2 | 43 | 22 | 13528 | 28.6004228329809 | 0.0661713018626445 | 1 | 0.284745061622156 | 68.0461654529877
GO:0050804~regulation of synaptic transmission | EGFR, TNF, PTGS2 | 3 | 43 | 136 | 13528 | 6.93980848153214 | 0.0665443151404792 | 1 | 0.28537818716371 | 68.2582015642884
GO:0001755~neural crest cell migration | EDNRB, CFL1 | 2 | 43 | 23 | 13528 | 27.3569261880687 | 0.0690752560550927 | 1 | 0.294003011064233 | 69.6623387301595
[NAME]~positive regulation of translation | IL6, TNF | 2 | 43 | 23 | 13528 | 27.3569261880687 | 0.0690752560550927 | 1 | 0.294003011064233 | 69.6623387301595
GO:0009410~response to xenobiotic stimulus | CYP1A1, [NAME] | 2 | 43 | 23 | 13528 | 27.3569261880687 | 0.0690752560550927 | 1 | 0.294003011064233 | 69.6623387301595
GO:0043405~regulation of MAP kinase activity | EGFR, TNF, IL1B | 3 | 43 | 141 | 13528 | 6.69371598218703 | 0.070862743183525 | 1 | 0.299782910890972 | 70.6186062070293
GO:0006259~DNA metabolic process | XRCC3, TP53, TOP2A, DNMT3B, SOD2 | 5 | 43 | 506 | 13528 | 3.10874161228054 | 0.0708750249885198 | 1 | 0.299042562309052 | 70.6250775989149
GO:0051785~positive regulation of nuclear division | TNF, IL1B | 2 | 43 | 25 | 13528 | 25.1683720930232 | 0.0748567420997979 | 1 | 0.312632868352728 | 72.6539052401958
GO:0042743~hydrogen peroxide metabolic process | CYP1A1, SOD2 | 2 | 43 | 25 | 13528 | 25.1683720930232 | 0.0748567420997979 | 1 | 0.312632868352728 | 72.6539052401958
GO:0045840~positive regulation of mitosis | TNF, IL1B | 2 | 43 | 25 | 13528 | 25.1683720930232 | 0.0748567420997979 | 1 | 0.312632868352728 | 72.6539052401958
GO:0045862~positive regulation of proteolysis | TNF, IL1B | 2 | 43 | 25 | 13528 | 25.1683720930232 | 0.0748567420997979 | 1 | 0.312632868352728 | 72.6539052401958
GO:0033365~protein localization in organelle | TNF, TP53, NFKBIA | 3 | 43 | 146 | 13528 | 6.464479133482 | 0.0752711866778933 | 1 | 0.313306610913359 | 72.857336464375
GO:0051969~regulation of transmission of nerve impulse | EGFR, TNF, PTGS2 | 3 | 43 | 147 | 13528 | 6.42050308495491 | 0.0761633543912668 | 1 | 0.315672214432609 | 73.2904421709005
GO:0006917~induction of apoptosis | CDKN1B, TNF, HMOX1, TP53 | 4 | 43 | 320 | 13528 | 3.93255813953488 | 0.0765963222566366 | 1 | 0.316396931619661 | 73.4982786173797
GO:0051249~regulation of lymphocyte activation | IL6, IL1B, CD40 | 3 | 43 | 148 | 13528 | 6.37712130735386 | 0.0770589476104029 | 1 | 0.317221524389653 | 73.7186709869744
GO:0001525~angiogenesis | HMOX1, IL1B, [NAME] | 3 | 43 | 148 | 13528 | 6.37712130735386 | 0.0770589476104029 | 1 | 0.317221524389653 | 73.7186709869744
GO:0012502~induction of programmed cell death | CDKN1B, TNF, HMOX1, TP53 | 4 | 43 | 321 | 13528 | 3.92030717959863 | 0.0771571565738654 | 1 | 0.316761914794645 | 73.7652350130261
GO:0042311~vasodilation | EDNRB, SOD2 | 2 | 43 | 26 | 13528 | 24.2003577817531 | 0.0777343261045195 | 1 | 0.317981546382715 | 74.0373263412173
GO:0045766~positive regulation of angiogenesis | IL1B, [NAME] | 2 | 43 | 26 | 13528 | 24.2003577817531 | 0.0777343261045195 | 1 | 0.317981546382715 | 74.0373263412173
GO:0051353~positive regulation of oxidoreductase activity | TNF, IL1B | 2 | 43 | 26 | 13528 | 24.2003577817531 | 0.0777343261045195 | 1 | 0.317981546382715 | 74.0373263412173
GO:0050994~regulation of lipid catabolic process | TNF, IL1B | 2 | 43 | 26 | 13528 | 24.2003577817531 | 0.0777343261045195 | 1 | 0.317981546382715 | 74.0373263412173
GO:0007548~sex differentiation | CCND1, BCL2, [NAME] | 3 | 43 | 151 | 13528 | 6.25042353303557 | 0.0797659944236242 | 1 | 0.324243321520777 | 74.9741483478306
GO:0033077~T cell differentiation in the thymus | BCL2, TP53 | 2 | 43 | 27 | 13528 | 23.3040482342807 | 0.0806031720765795 | 1 | 0.326321102414869 | 75.3508559932778
GO:0045732~positive regulation of protein catabolic process | TNF, IL1B | 2 | 43 | 27 | 13528 | 23.3040482342807 | 0.0806031720765795 | 1 | 0.326321102414869 | 75.3508559932778
GO:0003044~regulation of systemic arterial blood pressure mediated by a chemical signal | [NAME], SOD2 | 2 | 43 | 27 | 13528 | 23.3040482342807 | 0.0806031720765795 | 1 | 0.326321102414869 | 75.3508559932778
GO:0006006~glucose metabolic process | ALDOA, TNF, ENO1 | 3 | 43 | 153 | 13528 | 6.16871865025079 | 0.081587298141893 | 1 | 0.328885821504594 | 75.7868699287546
GO:0007173~epidermal growth factor receptor signaling pathway | EGFR, AREG | 2 | 43 | 28 | 13528 | 22.4717607973421 | 0.0834633059027742 | 1 | 0.334459857404937 | 76.5980203666684
GO:0045833~negative regulation of lipid metabolic process | TNF, IL1B | 2 | 43 | 28 | 13528 | 22.4717607973421 | 0.0834633059027742 | 1 | 0.334459857404937 | 76.5980203666684
GO:0006913~nucleocytoplasmic transport | TNF, TP53, NFKBIA | 3 | 43 | 156 | 13528 | 6.05008944543828 | 0.0843436016626462 | 1 | 0.336613880439369 | 76.9697741353403
[NAME] ending in birth or egg hatching | ADAM10, CYP1A1, [NAME], TP53 | 4 | 43 | 334 | 13528 | 3.76772037320707 | 0.0846144774171657 | 1 | 0.336702770369838 | 77.0830448879555
[NAME]nuclear transport | TNF, TP53, NFKBIA | 3 | 43 | 158 | 13528 | 5.97350603473653 | 0.0861970460836767 | 1 | 0.341180859790044 | 77.7344222224203
GO:0006778~porphyrin metabolic process | CYP1A1, HMOX1 | 2 | 43 | 29 | 13528 | 21.6968724939855 | 0.0863147533936392 | 1 | 0.340746822322707 | 77.7821679704743
GO:0033013~tetrapyrrole metabolic process | CYP1A1, HMOX1 | 2 | 43 | 29 | 13528 | 21.6968724939855 | 0.0863147533936392 | 1 | 0.340746822322707 | 77.7821679704743
GO:0050921~positive regulation of chemotaxis | IL6, ADAM10 | 2 | 43 | 29 | 13528 | 21.6968724939855 | 0.0863147533936392 | 1 | 0.340746822322707 | 77.7821679704743
[NAME] development | EGFR, IL6, BCL2, SOD2 | 4 | 43 | 339 | 13528 | 3.71214927625711 | 0.0875635308872643 | 1 | 0.34406526459627 | 78.2828192298059
GO:0007566~embryo implantation | PTGS2, IL1B | 2 | 43 | 30 | 13528 | 20.9736434108527 | 0.0891575402971349 | 1 | 0.348486694274624 | 78.9064785968708
GO:0042990~regulation of transcription factor import into nucleus | TNF, NFKBIA | 2 | 43 | 30 | 13528 | 20.9736434108527 | 0.0891575402971349 | 1 | 0.348486694274624 | 78.9064785968708
GO:0045768~positive regulation of anti-apoptosis | IL6, HMOX1 | 2 | 43 | 30 | 13528 | 20.9736434108527 | 0.0891575402971349 | 1 | 0.348486694274624 | 78.9064785968708
GO:0032388~positive regulation of intracellular transport | TNF, IL1B | 2 | 43 | 30 | 13528 | 20.9736434108527 | 0.0891575402971349 | 1 | 0.348486694274624 | 78.9064785968708
GO:0050920~regulation of chemotaxis | IL6, ADAM10 | 2 | 43 | 31 | 13528 | 20.2970742685671 | 0.0919916922636631 | 1 | 0.356889082101719 | 79.9739717968775
[NAME]~cellular amino acid derivative metabolic process | CYP1A1, DNMT3B, SOD2 | 3 | 43 | 166 | 13528 | 5.68562622583356 | 0.0937333776222494 | 1 | 0.361660412420066 | 80.6045665550578
GO:0050767~regulation of neurogenesis | BCL2, TP53, DNMT3B | 3 | 43 | 166 | 13528 | 5.68562622583356 | 0.0937333776222494 | 1 | 0.361660412420066 | 80.6045665550578
GO:0030168~platelet activation | IL6, CD40 | 2 | 43 | 32 | 13528 | 19.6627906976744 | 0.0948172349019194 | 1 | 0.364280905132905 | 80.9875149651542
GO:0007006~mitochondrial membrane organization | BCL2, TP53 | 2 | 43 | 32 | 13528 | 19.6627906976744 | 0.0948172349019194 | 1 | 0.364280905132905 | 80.9875149651542
GO:0045941~positive regulation of transcription | E2F1, IL6, TNF, TP53, NFKBIA | 5 | 43 | 564 | 13528 | 2.78904832591126 | 0.0964775928089197 | 1 | 0.368707722949207 | 81.5603956464856
GO:0014033~neural crest cell differentiation | EDNRB, CFL1 | 2 | 43 | 33 | 13528 | 19.0669485553206 | 0.0976341937122623 | 1 | 0.371502951775748 | 81.9498309728981
GO:0007569~cell aging | BCL2, TP53 | 2 | 43 | 33 | 13528 | 19.0669485553206 | 0.0976341937122623 | 1 | 0.371502951775748 | 81.9498309728981
[NAME]~DNA damage response, signal transduction resulting in induction of apoptosis | HMOX1, TP53 | 2 | 43 | 33 | 13528 | 19.0669485553206 | 0.0976341937122623 | 1 | 0.371502951775748 | 81.9498309728981
GO:0014032~neural crest cell development | EDNRB, CFL1 | 2 | 43 | 33 | 13528 | 19.0669485553206 | 0.0976341937122623 | 1 | 0.371502951775748 | 81.9498309728981
GO:0050871~positive regulation of B cell activation | IL6, CD40 | 2 | 43 | 33 | 13528 | 19.0669485553206 | 0.0976341937122623 | 1 | 0.371502951775748 | 81.9498309728981