Spreadsheet: c0aeee92-6e13-474d-b066-33360f149dbb
Sheet: Sheet1

Unnamed: 0 | Table S9. Experimentally determined virulence-associated genes of Mycobacterium tuberculosis and homologs in non-pathogenic Actinobacteria. | Unnamed: 2 | Unnamed: 3
Gene | Product | References | Orthologs in non-pathogenic Actinobacteria
Rv0046c | MYO-INOSITOL-1-PHOSPHATE SYNTHASE INO1 (Inositol 1-phosphate synthetase) (D-glucose 6-phosphate cycloaldolase) (Glucose 6-phosphate cyclase) ([NAME]) | [NAME] et al., 2004 | YES
[NAME] | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv0099 | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | Sassetti and Rubin, 2003
Rv0100 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv0101 | PROBABLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE) | Sassetti and Rubin, 2003 | YES
Rv0126 | TREHALOSE SYNTHASE TRES | [NAME] et [NAME], 2003 | YES
Rv0153c | PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB (PROTEIN-TYROSINE-PHOSPHATASE) (PTPase) | [NAME], 2009 | YES
Rv0169 | MCE-FAMILY PROTEIN MCE1A | Sassetti and Rubin, 2003 | YES
Rv0170 | MCE-FAMILY PROTEIN MCE1B | Sassetti and Rubin, 2003 | YES
Rv0171 | MCE-FAMILY PROTEIN MCE1C | Sassetti and Rubin, 2003 | YES
Rv0173 | POSSIBLE MCE-FAMILY LIPOPROTEIN LPRK (MCE-FAMILY LIPOPROTEIN MCE1E) | Sassetti and Rubin, 2003 | YES
Rv0175 | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv0176 | PROBABLE CONSERVED MCE ASSOCIATED TRANSMEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv0199 | PROBABLE CONSERVED MEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv0204c | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv0216 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv0218 | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv0249c | PROBABLE SUCCINATE DEHYDROGENASE [MEMBRANE ANCHOR SUBUNIT] (SUCCINIC DEHYDROGENASE) | Sassetti and Rubin, 2003 | YES
Rv0326 | HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv0350 | PROBABLE CHAPERONE PROTEIN [NAME] (HEAT SHOCK PROTEIN 70) (HEAT SHOCK 70 KDA PROTEIN) (HSP70) | Hingley-Wilson et al., 2003 | YES
[NAME] | PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR [NAME] (MERR FAMILY) | Hingley-Wilson et al., 2003 | YES
Rv0362 | POSSIBLE Mg2+ TRANSPORT TRANSMEMBRANE PROTEIN MGTE | Honer zu Bentrup and [NAME], 2001 | YES
Rv0386 | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LUXR/UHPA-FAMILY) | Agarwal et al., 2009 | YES
Rv0410c | SERINE/THREONINE-PROTEIN KINASE PKNG (PROTEIN KINASE G) (STPK G) | [NAME], 2004 | YES
Rv0414c | PROBABLE THIAMINE-PHOSPHATE PYROPHOSPHORYLASE THIE (TMP PYROPHOSPHORYLASE) (TMP-PPASE) (THIAMINE-PHOSPHATE SYNTHASE) | Sassetti and Rubin, 2003 | YES
Rv0427c | PROBABLE EXODEOXYRIBONUCLEASE III PROTEIN XTHA (EXONUCLEASE III) (EXO III) (AP ENDONUCLEASE VI) | Sassetti and Rubin, 2003 | YES
Rv0450c | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL4 | Camacho et al., 1999 | YES
Rv0467 | ISOCITRATE LYASE ICL (ISOCITRASE) (ISOCITRATASE) | Hingley-Wilson et al., 2003 | YES
Rv0469 | POSSIBLE MYCOLIC ACID SYNTHASE UMAA | [NAME] et al., 2006 | YES
Rv0470c | HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv0475 | IRON-REGULATED HEPARIN BINDING HEMAGGLUTININ HBHA (ADHESIN) | Honer zu Bentrup and [NAME], 2001 | YES
Rv0490 | PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 | Sassetti and Rubin, 2003 | YES
Rv0500 | PROBABLE PYRROLINE-5-CARBOXYLATE REDUCTASE PROC (P5CR) (P5C REDUCTASE) | Honer zu Bentrup and [NAME], 2001 | YES
Rv0507 | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL2 | Camacho et al., 1999 | YES
Rv0566c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv0636 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv0643c | METHOXY MYCOLIC ACID SYNTHASE 3 [NAME] (METHYL MYCOLIC ACID SYNTHASE 3) (MMA3) (HYDROXY MYCOLIC ACID SYNTHASE) | Sassetti and Rubin, 2003 | YES
Rv0655 | POSSIBLE RIBONUCLEOTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER MKL | Sassetti and Rubin, 2003 | YES
Rv0670 | PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) | Sassetti and Rubin, 2003 | YES
Rv0687 | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | Sassetti and Rubin, 2003 | YES
Rv0768 | PROBABLE ALDEHYDE DEHYDROGENASE NAD DEPENDENT ALDA (ALDEHYDE DEHYDROGENASE [NAD+]) | Hingley-Wilson et al., 2003 | YES
Rv0780 | PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE PURC (SAICAR SYNTHETASE) | Honer zu Bentrup and [NAME], 2001 | YES
Rv0867c | POSSIBLE RESUSCITATION-PROMOTING FACTOR RPFA | [NAME], 2008 | YES
Rv0930 | PROBABLE PHOSPHATE-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER PSTA1 | [NAME] et al., 2006 | YES
Rv0950c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv0981 | [NAME] (TWO COMPONENT RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN) | [NAME] et [NAME], 2003 | YES
Rv1009 | Probable resuscitation-promoting factor rpfB | [NAME], 2008 | YES
Rv1013 | PUTATIVE POLYKETIDE SYNTHASE PKS16 | Sassetti and Rubin, 2003 | YES
Rv1016c | PROBABLE CONSERVED LIPOPROTEIN LPQT | Sassetti and Rubin, 2003 | YES
Rv1021 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1027c | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN KDPE | [NAME] et [NAME], 2003 | YES
Rv1028c | PROBABLE SENSOR PROTEIN KDPD | Sassetti and Rubin, 2003 | YES
Rv1031 | Probable Potassium-transporting ATPase C chain KDPC (Potassium-translocating ATPase C chain) (ATP phosphohydrolase [potassium-transporting] C chain) (Potassium binding and translocating subunit C) | [NAME] et al., 2006 | YES
Rv1032c | TWO COMPONENT SENSOR HISTIDINE KINASE TRCS | [NAME] et [NAME], 2003 | YES
Rv1092c | Probable pantothenate [NAME] (Pantothenic acid kinase) | Sassetti and Rubin, 2003 | YES
[NAME] | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1109c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1111c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv1128c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1144 | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | Sassetti and Rubin, 2003 | YES
Rv1161 | PROBABLE RESPIRATORY NITRATE REDUCTASE (ALPHA CHAIN) NARG | Hingley-Wilson et al., 2003 | YES
Rv1162 | PROBABLE RESPIRATORY NITRATE REDUCTASE (BETA CHAIN) NARH | Hingley-Wilson et al., 2003 | YES
Rv1163 | PROBABLE RESPIRATORY NITRATE REDUCTASE (DELTA CHAIN) NARJ | Hingley-Wilson et al., 2003 | YES
Rv1164 | PROBABLE RESPIRATORY NITRATE REDUCTASE (GAMMA CHAIN) NARI | Hingley-Wilson et al., 2003 | YES
[NAME] | PROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA3 | [NAME] et al., 2006 | YES
Rv1183 | PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL10 | Sassetti and Rubin, 2003 | YES
Rv1184c | POSSIBLE EXPORTED PROTEIN | Sassetti and Rubin, 2003
Rv1185c | PROBABLE FATTY-ACID--CoA LIGASE FADD21 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | Sassetti and Rubin, 2003 | YES
Rv1192 | HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv1204c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv1211 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1212c | PUTATIVE GLYCOSYL TRANSFERASE | [NAME], 2008 | YES
Rv1224 | Probable protein TatB | Sassetti and Rubin, 2003 | YES
Rv1235 | PROBABLE SUGAR-BINDING LIPOPROTEIN LPQY | Sassetti and Rubin, 2003 | YES
Rv1236 | PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGA | Sassetti and Rubin, 2003 | YES
Rv1237 | PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGB | Sassetti and Rubin, 2003 | YES
Rv1238 | PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC | Sassetti and Rubin, 2003 | YES
Rv1244 | PROBABLE LIPOPROTEIN LPQZ | Sassetti and Rubin, 2003 | YES
Rv1272c | PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER | Sassetti and Rubin, 2003 | YES
Rv1284 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1293 | PROBABLE DIAMINOPIMELATE DECARBOXYLASE LYSA (DAP DECARBOXYLASE) | Honer zu Bentrup and [NAME], 2001 | YES
[NAME] | PROBABLE ATP SYNTHASE A CHAIN ATPB (PROTEIN 6) | Sassetti and Rubin, 2003 | YES
Rv1323 | PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA4 (ACETOACETYL-CoA THIOLASE) | Sassetti and Rubin, 2003 | YES
[NAME] | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1333 | PROBABLE HYDROLASE | Sassetti and Rubin, 2003 | YES
Rv1338 | PROBABLE GLUTAMATE RACEMASE MURI | Sassetti and Rubin, 2003 | YES
Rv1350 | PROBABLE 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG2 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) | [NAME] et al., 2006 | YES
Rv1371 | PROBABLE CONSERVED MEMBRANE PROTEIN | Sassetti and Rubin, 2003
Rv1395 | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN | Camacho et al., 1999
Rv1405c | PUTATIVE METHYLTRANSFERASE | Sassetti and Rubin, 2003 | YES
Rv1410c | AMINOGLYCOSIDES/TETRACYCLINE-TRANSPORT INTEGRAL MEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1411c | PROBABLE CONSERVED [NAME] | Sassetti and Rubin, 2003 | YES
[NAME] | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1460 | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1463 | PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER | Hingley-Wilson et al., 2003 | YES
Rv1464 | PROBABLE CYSTEINE DESULFURASE CSD | Hingley-Wilson et al., 2003 | YES
Rv1465 | POSSIBLE NITROGEN FIXATION RELATED PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1469 | PROBABLE CATION TRANSPORTER P-TYPE ATPASE D CTPD | Sassetti and Rubin, 2003 | YES
Rv1473 | PROBABLE MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER | Hingley-Wilson et al., 2003 | YES
Rv1477 | HYPOTHETICAL INVASION PROTEIN | Hett et al., 2008 | YES
[NAME] | HYPOTHETICAL INVASION PROTEIN | Hett et al., 2008 | YES
Rv1514c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1524 | Probable glycosyltransferase | Sassetti and Rubin, 2003 | YES
Rv1539 | PROBABLE LIPOPROTEIN SIGNAL PEPTIDASE LSPA | [NAME] et al., 2008 | YES
Rv1560 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv1568 | PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA | Sassetti and Rubin, 2003 | YES
Rv1569 | PROBABLE 8-AMINO-7-OXONONANOATE SYNTHASE BIOF1 (AONS) (8-AMINO-7-KETOPELARGONATE SYNTHASE) (7-KETO-8-AMINO-PELARGONIC ACID SYNTHETASE) (7-KAP SYNTHETASE) (L-ALANINE--PIMELYL CoA LIGASE) | Sassetti and Rubin, 2003 | YES
Rv1589 | PROBABLE BIOTIN SYNTHETASE BIOB | Sassetti and Rubin, 2003 | YES
Rv1590 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1604 | PROBABLE INOSITOL-MONOPHOSPHATASE IMPA (IMP) | [NAME] et al., 2006 | YES
Rv1640c | Possible lysyl-tRNA synthetase 2 lysX | Sassetti and Rubin, 2003 | YES
[NAME] | PE-PGRS FAMILY PROTEIN | [NAME] et [NAME], 2003
Rv1653 | Probable Glutamate n-acetyltransferase argJ | Sassetti and Rubin, 2003 | YES
Rv1696 | PROBABLE DNA REPAIR PROTEIN RECN (RECOMBINATION PROTEIN N) | Sassetti and Rubin, 2003 | YES
Rv1710 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1736c | PROBABLE NITRATE REDUCTASE NARX | Hingley-Wilson et al., 2003 | YES
Rv1737c | POSSIBLE NITRATE/NITRITE TRANSPORTER NARK2 | Hingley-Wilson et al., 2003 | YES
Rv1807 | PPE FAMILY PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1811 | POSSIBLE Mg2+ TRANSPORT P-TYPE ATPASE C MGTC | Buchmeier et al., 2000
Rv1821 | POSSIBLE PREPROTEIN TRANSLOCASE ATPase SECA2 | Sassetti and Rubin, 2003 | YES
Rv1832 | Probable glycine dehydrogenase gcvB (Glycine decarboxylase) (Glycine cleavage system P-protein) | Hingley-Wilson et al., 2003 | YES
Rv1857 | PROBABLE MOLYBDATE-BINDING LIPOPROTEIN MODA | Camacho et al., 1999 | YES
Rv1884c | PROBABLE RESUSCITATION-PROMOTING FACTOR RPFC | [NAME], 2008 | YES
Rv1930c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1931c | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN | Sassetti and Rubin, 2003 | YES
Rv1936 | POSSIBLE MONOOXYGENASE | Cirillo et al., 2009
Rv1937 | POSSIBLE OXYGENASE | Cirillo et al., 2009
Rv1938 | PROBABLE EPOXIDE HYDROLASE EPHB (EPOXIDE HYDRATASE) | Cirillo et al., 2009
Rv1939 | PROBABLE OXIDOREDUCTASE | Sassetti and Rubin, 2003 | YES
Rv1940 | Probable [NAME] biosynthesis protein ribA1 (GTP cyclohydrolase II) | Cirillo et al., 2009
[NAME] | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | Cirillo et al., 2009
Rv1974 | PROBABLE CONSERVED MEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv2004c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv2031c | HEAT SHOCK PROTEIN HSPX (ALPHA-CRSTALLIN HOMOLOG) (14 kDa ANTIGEN) (HSP16.3) | Hingley-Wilson et al., 2003 | YES
Rv2038c | Probable sugar-transport ATP-binding protein ABC transporter | Sassetti and Rubin, 2003 | YES
Rv2040c | Probable sugar-transport integral membrane protein ABC transporter | Sassetti and Rubin, 2003
Rv2048c | Probable polyketide synthase pks12 | Sassetti and Rubin, 2003 | YES
Rv2063 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv2072c | Probable precorrin-6y methyltransferase CobL | Sassetti and Rubin, 2003 | YES
Rv2115c | Probable ATPase | [NAME] et [NAME], 2005 | YES
Rv2192c | Probable anthranilate phosphoribosyltransferase [NAME] | Honer zu Bentrup and [NAME], 2001 | YES
Rv2211c | Probable aminomethyltransferase GcvT (Glycine cleavage system T protein) | Sassetti and Rubin, 2003 | YES
Rv2215 | Probable pyruvate dehydrogenase (E2 component) SucB | Agarwal and Bishai, 2009 | YES
Rv2220 | GLUTAMINE SYNTHETASE GLNA1 (GLUTAMINE SYNTHASE) (GS-I) | Honer zu Bentrup and [NAME], 2001 | YES
Rv2224c | Probable exported protease | Sassetti and Rubin, 2003 | YES
Rv2231c | Possible aminotransferase CobC | Sassetti and Rubin, 2003 | YES
Rv2234 | PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPA (PROTEIN-TYROSINE-PHOSPHATASE) (PTPase) (LMW PHOSPHATASE) | [NAME], 2005 | YES
Rv2241 | Probable pyruvate dehydrogenase E1 component aceE (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE) | Sassetti and Rubin, 2003 | YES
Rv2275 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv2277c | Possible glycerolphosphodiesterase | Sassetti and Rubin, 2003
Rv2335 | PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT) | Sassetti and Rubin, 2003 | YES
Rv2348c | HYPOTHETICAL PROTEIN | Honer zu Bentrup and [NAME], 2001
Rv2349c | PROBABLE PHOSPHOLIPASE C 3 PLCC | Honer zu Bentrup and [NAME], 2001
Rv2350c | [NAME] PHOSPHOLIPASE C 2 PLCB | Honer zu Bentrup and [NAME], 2001
Rv2351c | [NAME] PHOSPHOLIPASE C 1 PLCA ([NAME]) | Honer zu Bentrup and [NAME], 2001
Rv2359 | PROBABLE FERRIC UPTAKE REGULATION PROTEIN FURB | Sassetti and Rubin, 2003 | YES
Rv2374c | PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HRCA | Sassetti and Rubin, 2003 | YES
[NAME] | PUTATIVE ISOCHORISMATE SYNTHASE MBTI | [NAME] et al., 2006 | YES
Rv2387 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv2388c | PROBABLE OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE HEMN (COPROPORPHYRINOGENASE) (COPROGEN OXIDASE) | Sassetti and Rubin, 2003 | YES
Rv2389c | PROBABLE RESUSCITATION-PROMOTING FACTOR RPFD | [NAME], 2008 | YES
[NAME] | [NAME] NITRITE REDUCTASE NIRA | Sassetti and Rubin, 2003 | YES
Rv2437 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv2450c | PROBABLE RESUSCITATION-PROMOTING FACTOR RPFE | [NAME], 2008 | YES
Rv2472 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv2483c | POSSIBLE TRANSMEMBRANE PHOSPHOLIPID BIOSYNTHESIS BIFUNCTIONNAL ENZYME PLSC: PUTATIVE L-3-PHOSPHOSERINE PHOSPHATASE (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSP) (PSPASE) + 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE (1-AGP ACYLTRANSFERASE) (1-AGPAT) ([NAME]) ([NAME]) | Sassetti and Rubin, 2003 | YES
Rv2502c | PROBABLE ACETYL-/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD1 | Sassetti and Rubin, 2003 | YES
Rv2553c | PROBABLE CONSERVED MEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv2583c | PROBABLE GTP PYROPHOSPHOKINASE RELA (ATP:GTP 3'-PYROPHOSPHOTRANSFERASE) (PPGPP SYNTHETASE I) ((P)PPGPP SYNTHETASE) (GTP DIPHOSPHOKINASE) | [NAME] et [NAME], 2003 | YES
Rv2603c | HIGHLY CONSERVED HYPOTHETICAL PROTEIN | [NAME] et al., 2003 | YES
Rv2604c | CONSERVED HYPOTHETICAL PROTEIN | [NAME] et al., 2004 | YES
Rv2605c | PROBABLE ACYL-CoA THIOESTERASE II TESB2 (TEII) | [NAME] et al., 2004 | YES
Rv2606c | Possible pyridoxine biosynthesis protein | [NAME] et al., 2006 | YES
Rv2623 | CONSERVED HYPOTHETICAL PROTEIN TB31.7 | Cheruvu et al., 2007 | YES
Rv2692 | TRK SYSTEM POTASSIUM UPTAKE PROTEIN CEOC | Sassetti and Rubin, 2003 | YES
[NAME] | CONSERVED HYPOTHETICAL ALANINE AND GLYCINE AND VALINE RICH PROTEIN | Sassetti and Rubin, 2003 | YES
Rv2702 | POLYPHOSPHATE GLUCOKINASE PPGK (POLYPHOSPHATE-GLUCOSE PHOSPHOTRANSFERASE) | Sassetti and Rubin, 2003 | YES
Rv2707 | PROBABLE CONSERVED TRANSMEMBRANE ALANINE AND LEUCINE RICH PROTEIN | Sassetti and Rubin, 2003 | YES
Rv2734 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv2780 | SECRETED L-ALANINE DEHYDROGENASE ALD (40 KDA ANTIGEN) (TB43) | Hingley-Wilson et al., 2003 | YES
Rv2808 | HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv2813 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv2845c | PROBABLE PROLYL-TRNA SYNTHETASE PROS (PROLINE--TRNA LIGASE) (PRORS) (GLOBAL RNA SYNTHESIS FACTOR) (PROLINE TRANSLASE) | Sassetti and Rubin, 2003 | YES
Rv2857c | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | Sassetti and Rubin, 2003 | YES
Rv2868c | PROBABLE GCPE PROTEIN | [NAME] et al., 2006 | YES
Rv2885c | PROBABLE TRANSPOSASE | Sassetti and Rubin, 2003 | YES
Rv2912c | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) | Sassetti and Rubin, 2003 | YES
Rv2921c | PROBABLE CELL DIVISION PROTEIN FTSY (SRP RECEPTOR) (SIGNAL RECOGNITION PARTICLE RECEPTOR) | Sassetti and Rubin, 2003 | YES
Rv2930 | FATTY-ACID-CoA LIGASE FADD26 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | Camacho et al., 1999 | YES
Rv2931 | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | Hingley-Wilson et al., 2003
Rv2932 | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | Hingley-Wilson et al., 2003
Rv2933 | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | Hingley-Wilson et al., 2003
Rv2934 | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | Hingley-Wilson et al., 2003
Rv2935 | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | Hingley-Wilson et al., 2003
Rv2936 | PROBABLE DAUNORUBICIN-DIM-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER DRRA | Sassetti and Rubin, 2003 | YES
Rv2937 | PROBABLE DAUNORUBICIN-DIM-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DRRB | Sassetti and Rubin, 2003 | YES
Rv2938 | PROBABLE DAUNORUBICIN-DIM-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DRRC | Sassetti and Rubin, 2003 | YES
Rv2941 | FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | Hingley-Wilson et al., 2003
Rv2942 | CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL7 | Sassetti and Rubin, 2003 | YES
Rv2945c | PROBABLE CONSERVED LIPOPROTEIN LPPX | Sassetti and Rubin, 2003
Rv2946c | PROBABLE POLYKETIDE SYNTHASE PKS1 | [NAME] et [NAME], 2003
Rv2947c | PROBABLE POLYKETIDE SYNTHASE PKS15 | [NAME] et [NAME], 2003
[NAME] | PROBABLE URACIL-DNA GLYCOSYLASE UNG (UDG) | Sassetti and Rubin, 2003 | YES
Rv2981c | PROBABLE D-ALANINE--D-ALANINE LIGASE DDLA (D-ALANYLALANINE SYNTHETASE) (D-ALA-D-ALA LIGASE) | Sassetti and Rubin, 2003 | YES
Rv2987c | PROBABLE 3-ISOPROPYLMALATE DEHYDRATASE (SMALL SUBUNIT) LEUD (ISOPROPYLMALATE ISOMERASE) (ALPHA-IPM ISOMERASE) (IPMI) | Honer zu Bentrup and [NAME], 2001 | YES
Rv2998 | HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv3018c | PE FAMILY PROTEIN | Camacho et al., 1999 | YES
Rv3042c | PROBABLE PHOSPHOSERINE PHOSPHATASE SERB2 (PSP) (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSPASE) | Sassetti and Rubin, 2003 | YES
Rv3050c | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ASNC-FAMILY) | Sassetti and Rubin, 2003 | YES
Rv3061c | PROBABLE ACYL-CoA DEHYDROGENASE FADE22 | Sassetti and Rubin, 2003 | YES
Rv3083 | PROBABLE MONOOXYGENASE (HYDROXYLASE) | Cheruvu et al., 2007 | YES
Rv3084 | [NAME] | Cheruvu et al., 2007
Rv3085 | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | Cheruvu et al., 2007 | YES
Rv3086 | PROBABLE ZINC-TYPE ALCOHOL DEHYDROGENASE ADHD (ALDEHYDE REDUCTASE) | Cheruvu et al., 2007 | YES
Rv3087 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3088 | CONSERVED HYPOTHETICAL PROTEIN | Cheruvu et al., 2007
Rv3089 | PROBABLE CHAIN-FATTY-ACID-CoA LIGASE FADD13 (FATTY-ACYL-CoA SYNTHETASE) | Cheruvu et al., 2007
Rv3103c | HYPOTHETICAL PROLINE-RICH PROTEIN | Sassetti and Rubin, 2003
Rv3106 | NADPH:ADRENODOXIN OXIDOREDUCTASE FPRA (NADPH-FERREDOXIN REDUCTASE) | [NAME] et al., 2006 | YES
Rv3114 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv3132c | TWO COMPONENT SENSOR HISTIDINE KINASE DEVS | [NAME] et [NAME], 2003 | YES
Rv3133c | TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN [NAME] (PROBABLY LUXR/UHPA-FAMILY) | [NAME] et [NAME], 2003 | YES
Rv3168 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3178 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv3197 | PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER | Hingley-Wilson et al., 2003 | YES
Rv3210c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3223c | ALTERNATIVE RNA POLYMERASE SIGMA-E FACTOR (SIGMA-24) SIGH (RPOE) | Honer zu Bentrup and [NAME], 2001 | YES
Rv3229c | POSSIBLE LINOLEOYL-CoA DESATURASE (DELTA(6)-DESATURASE) | Sassetti and Rubin, 2003 | YES
Rv3236c | PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3246c | TWO COMPONENT SENSORY TRANSDUCTION TRANSCRIPTIONAL REGULATORY PROTEIN MTRA | Sassetti and Rubin, 2003 | YES
Rv3258c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3270 | PROBABLE METAL CATION-TRANSPORTING P-TYPE ATPASE C CTPC | Sassetti and Rubin, 2003 | YES
Rv3277 | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3286c | ALTERNATE RNA POLYMERASE SIGMA FACTOR SIGF | Hingley-Wilson et al., 2003 | YES
Rv3291c | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ASNC-FAMILY) | Parti et al., 2008 | YES
Rv3335c | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3368c | POSSIBLE OXIDOREDUCTASE | Hingley-Wilson et al., 2003 | YES
Rv3370c | PROBABLE DNA POLYMERASE III (ALPHA CHAIN) DNAE2 (DNA NUCLEOTIDYLTRANSFERASE) | Honer zu Bentrup and [NAME], 2001 | YES
Rv3371 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv3375 | PROBABLE AMIDASE AMID (ACYLAMIDASE) (ACYLASE) | Sassetti and Rubin, 2003
Rv3400 | PROBABLE HYDROLASE | Sassetti and Rubin, 2003 | YES
Rv3416 | TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB3 | [NAME] et [NAME], 2003 | YES
[NAME] | PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE GCP (GLYCOPROTEASE) | Sassetti and Rubin, 2003 | YES
Rv3472 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv3484 | POSSIBLE CONSERVED PROTEIN CPSA | Sassetti and Rubin, 2003
Rv3487c | PROBABLE ESTERASE/LIPASE LIPF | Camacho et al., 1999 | YES
Rv3489 | HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3495c | POSSIBLE MCE-FAMILY LIPOPROTEIN LPRN (MCE-FAMILY LIPOPROTEIN MCE4E) | Sassetti and Rubin, 2003 | YES
Rv3497c | MCE-FAMILY PROTEIN MCE4C | Sassetti and Rubin, 2003 | YES
[NAME] | MCE-FAMILY PROTEIN MCE4A | Sassetti and Rubin, 2003 | YES
Rv3501c | CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4A | Sassetti and Rubin, 2003 | YES
[NAME] | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE | Sassetti and Rubin, 2003 | YES
Rv3519 | HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3523 | PROBABLE LIPID CARRIER PROTEIN OR KETO ACYL-COA THIOLASE LTP3 | Sassetti and Rubin, 2003 | YES
Rv3534c | PROBABLE 4-HYDROXY-2-OXOVALERATE ALDOLASE (HOA) | Sassetti and Rubin, 2003 | YES
Rv3540c | PROBABLE LIPID TRANSFER PROTEIN OR KETO ACYL-COA THIOLASE LTP2 | Sassetti and Rubin, 2003 | YES
Rv3541c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3542c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3543c | PROBABLE ACYL-CoA DEHYDROGENASE FADE29 | [NAME], 2009 | YES
Rv3544c | PROBABLE ACYL-CoA DEHYDROGENASE FADE28 | Sassetti and Rubin, 2003 | YES
Rv3545c | PROBABLE CYTOCHROME P450 125 CYP125 | Sassetti and Rubin, 2003 | YES
Rv3551 | POSSIBLE COA-TRANSFERASE (ALPHA SUBUNIT) | Sassetti and Rubin, 2003 | YES
Rv3556c | PROBABLE ACETYL-CoA ACETYLTRANSFERASE FADA6 (ACETOACETYL-CoA THIOLASE) | Sassetti and Rubin, 2003 | YES
Rv3560c | PROBABLE ACYL-CoA DEHYDROGENASE FADE30 | Sassetti and Rubin, 2003 | YES
Rv3563 | PROBABLE ACYL-CoA DEHYDROGENASE FADE32 | Sassetti and Rubin, 2003 | YES
Rv3568c | PROBABLE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC (23OHBP OXYGENASE) (2,3-DIHYDROXYBIPHENYL DIOXYGENASE) (2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE) (DHBD) | [NAME], 2009 | YES
Rv3571 | POSSIBLE HEMOGLOBINE-RELATED PROTEIN HMP | Hingley-Wilson et al., 2003 | YES
Rv3574 | TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) | Sassetti and Rubin, 2003 | YES
Rv3588c | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | Sassetti and Rubin, 2003 | YES
Rv3601c | PROBABLE ASPARTATE 1-DECARBOXYLASE PRECURSOR PAND (ASPARTATE ALPHA-DECARBOXYLASE) | Honer zu Bentrup and [NAME], 2001 | YES
Rv3602c | PROBABLE PANTOATE--BETA-ALANINE LIGASE PANC (PANTOTHENATE SYNTHETASE) (PANTOATE ACTIVATING ENZYME) | Honer zu Bentrup and [NAME], 2001 | YES
Rv3614c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
[NAME] | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv3616c | CONSERVED HYPOTHETICAL ALANINE AND GLYCINE RICH PROTEIN | Sassetti and Rubin, 2003
Rv3631 | POSSIBLE TRANSFERASE (POSSIBLY GLYCOSYLTRANSFERASE) | Sassetti and Rubin, 2003 | YES
Rv3649 | PROBABLE HELICASE | Sassetti and Rubin, 2003 | YES
Rv3651 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3663c | PROBABLE DIPEPTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER DPPD | Sassetti and Rubin, 2003 | YES
Rv3671c | POSSIBLE MEMBRANE-ASSOCIATED SERINE PROTEASE | [NAME], 2008 | YES
Rv3683 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3701c | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3717 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3723 | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3758c | POSSIBLE OSMOPROTECTANT (GLYCINE BETAINE/CARNITINE/CHOLINE/L-PROLINE) TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER PROV | Sassetti and Rubin, 2003 | YES
Rv3764c | POSSIBLE TWO COMPONENT SENSOR KINASE | [NAME] et [NAME], 2003 | YES
Rv3765c | PROBABLE TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN | [NAME] et [NAME], 2003 | YES
Rv3781 | PROBABLE O-ANTIGEN/LIPOPOLYSACCHARIDE TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER RFBE | Sassetti and Rubin, 2003 | YES
Rv3794 | INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBA (ARABINOSYLINDOLYLACETYLINOSITOL SYNTHASE) | Sassetti and Rubin, 2003 | YES
Rv3805c | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3810 | EXPORTED REPETITIVE PROTEIN PRECURSOR PIRG (CELL SURFACE PROTEIN) (EXP53) | Sassetti and Rubin, 2003 | YES
Rv3812 | PE-PGRS FAMILY PROTEIN | [NAME] et [NAME], 2003
Rv3820c | POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA2 | [NAME] et al., 2006 | YES
Rv3825c | PROBABLE POLYKETIDE SYNTHASE PKS2 | [NAME] et [NAME], 2003 | YES
Rv3849 | CONSERVED HYPOTHETICAL PROTEIN | [NAME], 2008 | YES
Rv3855 | TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR | Sassetti and Rubin, 2003 | YES
Rv3864 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003
Rv3868 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3869 | POSSIBLE CONSERVED MEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3870 | POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3871 | CONSERVED HYPOTHETICAL PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3872 | PE FAMILY-RELATED PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3873 | PPE FAMILY PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3876 | CONSERVED HYPOTHETICAL PROLINE AND ALANINE RICH PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3877 | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3882c | POSSIBLE CONSERVED MEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3910 | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN | Sassetti and Rubin, 2003 | YES
Rv3913 | [NAME] REDUCTASE [NAME] ([NAME]) (TR) | Hingley-Wilson et al., 2003 | YES