Spreadsheet: bb14493e-6158-4974-bffd-f9b1c9be1c8c
Sheet: Sheet1

Table S8: Proteins identified as aggregation-prone and identified in RNAi screens for increased polyglutamine aggregation ([NAME], 2004) | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4
Uniprot ID | Gene WB ID | Gene name | Sequence name | protein name
O76577 | WBGene00004467 | rpn-11 | [NAME] | 26S proteasome non-ATPase regulatory subunit 14
P49196 | [NAME] | rps-12 | F54E7.2 | 40S ribosomal protein S12
Q9XVP0 | WBGene00004484 | rps-15 | F36A2.6 | 40S ribosomal protein S15
[NAME] | WBGene00004485 | rps-16 | T01C3.6 | 40S ribosomal protein S16
O18650 | WBGene00004488 | rps-19 | T05F1.3 | 40S ribosomal protein S19
P51403 | WBGene00004471 | rps-2 | C49H3.11 | 40S ribosomal protein S2
P49197 | WBGene00004490 | rps-21 | F37C12.11 | 40S ribosomal protein S21
O45499 | WBGene00004495 | rps-26 | F39B2.6 | 40S ribosomal protein S26
P48152 | WBGene00004472 | rps-3* | C23G10.3 | 40S ribosomal protein S3
P48154 | WBGene00004470 | rps-1 | F56F3.5 | 40S ribosomal protein S3a
P49041 | WBGene00004474 | rps-5 | T05E11.1 | 40S ribosomal protein S5
P46769 | WBGene00004469 | rps-0 | B0393.1 | 40S ribosomal protein SA
Q93572 | WBGene00004408 | rpa-0 | [NAME] | 60S acidic ribosomal protein P0
P91128 | [NAME] | rpl-13 | C32E8.2 | 60S ribosomal protein [NAME]
P91374 | WBGene00004427 | rpl-15 | [NAME] | 60S ribosomal protein L15
Q9BL19 | WBGene00004429 | rpl-17 | [NAME] | 60S ribosomal protein L17
O45946 | WBGene00004430 | rpl-18 | Y45F10D.12 | 60S ribosomal protein L18
[NAME] | WBGene00004432 | rpl-20 | E04A4.8 | 60S ribosomal protein L18a
O02639 | WBGene00004431 | rpl-19 | C09D4.5 | 60S ribosomal protein L19
P34334 | WBGene00004433 | rpl-21 | C14B9.7 | 60S ribosomal protein [NAME]
P48158 | WBGene00004435 | rpl-23 | B0336.10 | 60S ribosomal protein [NAME]
O01868 | WBGene00004436 | rpl-24.1 | D1007.12 | 60S ribosomal protein L24
P34662 | WBGene00004449 | rpl-35 | ZK652.4 | 60S ribosomal protein L35
P49405 | WBGene00004416 | rpl-5 | F54C9.5 | 60S ribosomal protein L5
P47991 | WBGene00004417 | rpl-6 | R151.3 | 60S ribosomal protein L6
[NAME] | WBGene00004418 | rpl-7 | F53G12.10 | 60S ribosomal protein L7
Q966C6 | WBGene00004419 | rpl-7A | Y24D9A.4 | 60S ribosomal protein L7a
Q9XVF7 | WBGene00004413 | rpl-2 | B0250.1 | 60S ribosomal protein L8
P27604 | WBGene00019322 | K02F2.2 | K02F2.2 | Adenosylhomocysteinase
O01541 | WBGene00000197 | ars-2 | F28H1.3 | Alanyl trna synthetase protein 2
Q19126 | [NAME] | asb-2* | F02E8.1 | Atp synthase b homolog protein 2
Q9XXK1 | [NAME] | phi-37* | H28O16.1 | ATP synthase subunit alpha, mitochondrial
P46561 | WBGene00000229 | atp-2* | C34E10.6 | ATP synthase subunit beta, mitochondrial
Q09544 | WBGene00019061 | F58F12.1 | F58F12.1 | ATP synthase subunit delta, mitochondrial
P29691 | WBGene00001167 | eft-2 | F25H5.4 | Elongation factor 2
P34339 | WBGene00001209 | egl-45* | C27D11.1 | Eukaryotic translation initiation factor 3 subunit A
O17915 | WBGene00004302 | ran-1 | K01G5.4 | GTP-binding nuclear protein ran-1
P09446 | WBGene00002005 | hsp-1 | F26D10.3 | Heat shock 70 kDa protein A
P11141 | WBGene00002010 | hsp-6 | C37H5.8 | Heat shock 70 kDa protein F, mitochondrial
Q21568 | WBGene00010896 | M28.5 | M28.5 | NHP2-like protein 1 homolog
Q19713 | [NAME] | frs-2 | F22B5.9 | Phenylalanyl-tRNA synthetase beta chain
[NAME] | WBGene00015734 | [NAME] | [NAME] | Probable coatomer subunit delta
Q21735 | WBGene00004305 | ran-4 | R05D11.3 | Probable nuclear transport factor 2
Q19626 | WBGene00006921 | vha-12* | F20B6.2 | Probable V-type proton ATPase subunit B
Q22494 | WBGene00020507 | vha-15 | T14F9.1 | Probable V-type proton ATPase subunit H 2
O76371 | WBGene00004505 | rpt-5 | F56H1.4 | Proteasome regulatory particle, atpase-like protein 5
Q20938 | WBGene00004462 | rpn-6 | F57B9.10 | Proteasome regulatory particle, non-atpase-like protein 6, isoform a
O61792 | WBGene00004464 | rpn-8 | R12E2.3 | Proteasome regulatory particle, non-atpase-like protein 8
Q95005 | WBGene00003925 | pas-4 | C36B1.4 | Proteasome subunit alpha type-7
O62102 | WBGene00003948 | pbs-2 | C47B2.4 | Proteasome subunit beta type
Q9XVE9 | WBGene00004426 | rpl-14 | C04F12.4 | Protein C04F12.4
Q17763 | WBGene00007385 | atp-5* | C06H2.1 | Protein C06H2.1
O45622 | WBGene00010405 | H19N07.1 | H19N07.1 | Protein H19N07.1
Q9U2U0 | WBGene00006698 | uaf-2 | Y116A8C.35 | Protein Y116A8C.35
O18240 | [NAME] | rps-18 | Y57G11C.16 | Protein Y57G11C.16
Q95XR0 | WBGene00021466 | Y39G10AR.8 | Y39G10AR.8 | Putative uncharacterized protein
[NAME] | WBGene00020391 | T10B5.5 | T10B5.5 | Putative uncharacterized protein T10B5.5
O01869 | WBGene00004479 | rps-10 | D1007.6 | Ribosomal protein, small subunit protein 10
Q18212 | WBGene00001840 | hel-1 | C26D10.2 | Spliceosome RNA helicase [NAME] homolog
P41988 | WBGene00000377 | cct-1 | T05C12.7 | T-complex protein 1 subunit alpha
P47207 | WBGene00011889 | T21B10.7 | T21B10.7 | T-complex protein 1 subunit beta
P47208 | WBGene00000379 | cct-4* | K01C8.10 | T-complex protein 1 subunit delta
P47209 | WBGene00000380 | cct-5 | C07G2.3 | T-complex protein 1 subunit epsilon
P46550 | WBGene00000381 | cct-6* | F01F1.8 | T-complex protein 1 subunit zeta
P54811 | WBGene00007352 | cdc-48.1 | C06A1.1 | Transitional endoplasmic reticulum ATPase homolog 1
P52275 | WBGene00006537 | tbb-2 | C36E8.5 | Tubulin beta-2 chain
C1P636 | WBGene00006699 | uba-1 | C47E12.5 | Ubiquitin-activating enzyme E1
Q95X44 | WBGene00006917 | vha-8 | [NAME] | Vacuolar h atpase protein 8
Q9XW92 | WBGene00013025 | vha-13 | Y49A3A.2 | V-type proton ATPase catalytic subunit A
Note: 156 out of 186 genes identified in [NAME] et al. (2004) were present in our compiled mass spectrometry proteome dataset.
Grey highlight marks proteins found in the age-dependent insoluble set.
* Also found to increase lifespan when inhibited by RNAi