Spreadsheet: 04f61ee5-8ecc-423c-9992-0ee15aff4ad7
Sheet: Table3_NetworkProteins

Additional File 3: Gene products in networks
Protein | Arsenic Directly Modulated? | Associated with As-Modulated Transcripts? | Cadmium Directly Modulated? | Associated with Cd-Modulated Transcripts? | [NAME]?
ACSL1 | Yes (up regulated)
ACOT8 |  |  | Yes (down regulated)
ADCY5 |  |  | Yes (down regulated)
ADCY6 |  |  |  | Yes
AFAP1L2 |  |  | Yes (down regulated) |  | Yes
AGT |  | Yes
[NAME] |  | Yes |  | Yes
ALB |  |  |  | Yes
ALDH1L1 | Yes (up regulated)
ALOXE3 |  |  | Yes (up regulated)
Alpha catenin |  |  |  | Yes
ANKRD13A | Yes (down regulated)
AP1G1 |  |  |  | Yes
AP1GBP1 |  |  | Yes (down regulated)
APH1A (includes EG:51107) |  |  |  | Yes
APH1B |  |  | Yes (up regulated)
APIP |  |  |  | Yes
ARRB1 |  |  |  | Yes
ASTN2 (includes EG:23245) |  |  | Yes (up regulated)
ATP2A1 |  |  | Yes (up regulated) |  | Yes
BCAS1 |  |  | Yes (up regulated)
beta-estradiol |  |  |  | Yes
BID |  |  | Yes (down regulated) |  | Yes
BIK |  |  |  | Yes
BIRC3 |  |  |  | Yes
C1ORF85 |  |  | Yes (down regulated)
C1ORF123 | Yes (up regulated)
CAPN1 |  |  |  | Yes
CASP12 (includes EG:12364) |  |  |  | Yes
CBARA1 |  |  | Yes (up regulated)
CCDC25 |  |  | Yes (up regulated)
CCNB1IP1 |  |  | Yes (up regulated)
CD151 |  |  | Yes (down regulated) |  | Yes
CDC2 |  |  |  | Yes
CEP97 | Yes (up regulated)
CHAD (includes EG:1101) |  |  | Yes (down regulated)
CNP |  |  |  | Yes
CNR2 | Yes (down regulated)
CP110 |  | Yes
CSNK2A1 |  | Yes
CTLA4 |  |  |  | Yes
CTSS |  | Yes
CYB5RL |  |  | Yes (down regulated)
[NAME] | Yes (up regulated)
DLGAP5 |  |  |  | Yes
DNAJB5 | Yes (up regulated)
DPM2 |  | Yes
DR1 | Yes (up regulated)
DRD5 |  |  |  | Yes
DSPP |  | Yes
[NAME] |  |  | Yes (down regulated)
DTX2 |  |  |  | Yes
DUT (includes EG:1854) |  |  |  | Yes
EDAR |  |  |  | Yes
EGFR |  |  |  | Yes
EIF2C2 | Yes (up regulated)
ENTPD1 |  | Yes
ERVWE1 |  |  | Yes (up regulated) |  | Yes
F7 |  |  |  | Yes
FAM86A | Yes (up regulated)
FER (includes EG:2241) |  |  | Yes (up regulated) |  | Yes
FREQ |  |  | Yes (up regulated)
FURIN |  | Yes
G3BP2 | Yes (up regulated)
G-protein gamma |  |  |  | Yes
GADD45 |  |  |  | Yes
GADD45A |  |  | Yes (up regulated) |  | Yes
GDI1 |  |  |  | Yes
[NAME] |  |  | Yes (down regulated)
GGA1 |  |  |  | Yes
[NAME] |  |  |  | Yes
GJB6 |  |  | Yes (down regulated)
GNMT |  |  |  | Yes
GRHPR |  |  | Yes (down regulated)
GTF2B |  | Yes
HCK |  |  |  | Yes
HES1 | Yes (up regulated) |  |  |  | Yes
HJURP |  |  | Yes (up regulated) |  | Yes
HNF4A |  | Yes |  | Yes
HSD17B8 |  |  | Yes (down regulated)
[NAME] |  | Yes
IFIT3 |  | Yes
IFIT5 |  | Yes
IFITM3 |  |  | Yes (down regulated)
IFNG |  | Yes |  | Yes
IGF1 |  |  |  | Yes
IL1RN | Yes (down regulated) |  |  |  | Yes
IL32 |  | Yes
IPO8 |  | Yes
IREB2 |  |  |  | Yes
ITGB1 |  |  |  | Yes
ITPK1 |  |  |  | Yes
Jnk |  |  |  | Yes
KCND2 |  |  |  | Yes
KCNJ2 |  |  | Yes (down regulated)
KCNJ4 |  |  |  | Yes
KIAA1219 | Yes (up regulated)
KRT16 |  |  | Yes (down regulated) |  | Yes
KRT6A | Yes (up regulated)
LAMP3 |  | Yes | Yes (up regulated)
LCN2 |  |  | Yes (up regulated) |  | Yes
[NAME] |  |  | Yes (up regulated)
LGALS9 |  | Yes
LIN28 |  | Yes | Yes (up regulated) |  | Yes
LIN7C |  |  |  | Yes
LONRF1 |  |  | Yes (down regulated)
[NAME] | Yes (down regulated)
LYSMD2 |  |  | Yes (down regulated)
MAP3K3 |  | Yes
MAP3K5 (includes EG:293015) |  |  |  | Yes
MAP4K2 |  |  |  | Yes
[NAME] |  | Yes |  | Yes
MAPK3 |  |  |  | Yes
MAPK8IP3 | Yes (down regulated) |  |  |  | Yes
MDM2 |  | Yes
MED18 |  |  | Yes (down regulated)
METTL1 | Yes (up regulated)
MEX3B | Yes (down regulated)
MIR18A |  | Yes |  | Yes
MIR197 |  |  |  | Yes
MIR204 |  |  |  | Yes
MIRN202 |  |  |  | Yes
MIR205 |  | Yes
MIR24-1 |  | Yes
MIRN298 (includes EG:723832) |  |  |  | Yes
MIRN343 |  |  |  | Yes
MOBKL1A | Yes (up regulated)
MRPL18 | Yes (up regulated)
MRPL28 |  |  | Yes (down regulated)
[NAME] |  | Yes
MTHFS |  |  | Yes (down regulated)
MTPN |  |  |  | Yes
MYC |  |  |  | Yes
MYCBP2 |  |  |  | Yes
NAMPT |  |  |  | Yes
NCKAP1L | Yes (up regulated)
NCSTN |  |  |  | Yes
NDUFA4 |  | Yes
NDUFA7 |  | Yes
NEK2 |  |  |  | Yes
NFE2L2 |  | Yes
NFkB (complex) |  |  |  | Yes
NOLC1 | Yes (up regulated)
NR3C1 |  |  |  | Yes
NRG4 | Yes (down regulated)
NUDT18 |  |  | Yes (up regulated)
NUP98 |  |  | Yes (down regulated)
OAS2 |  | Yes
OAS3 (includes EG:4940) |  | Yes
OASL |  | Yes
OLIG2 |  | Yes |  | Yes
ONECUT1 |  | Yes
OR2B11 |  |  | Yes (down regulated)
ORM1 |  | Yes
ORM2 |  | Yes
Oxidoreductase |  |  |  | Yes
P38 MAPK |  |  |  | Yes
PEG3 |  |  |  | Yes
PGRMC1 | Yes (up regulated)
PI3K |  |  |  | Yes
PIGA |  | Yes
PIGC |  | Yes
PIGH | Yes (up regulated)
PIGO | Yes (up regulated)
PIGP |  | Yes
PIGQ |  | Yes
PIGY (includes EG:84992) |  | Yes
PISD |  |  | Yes (down regulated)
PKC ALPHA/BETA |  | Yes
PLA2G12B |  |  | Yes (up regulated)
PLA2G6 |  | Yes
PLAA |  | Yes
PLN |  |  |  | Yes
PNKP |  | Yes
POLB |  |  |  | Yes
prostaglandin E2 |  |  |  | Yes
PSME3 |  |  |  | Yes
[NAME] |  |  | Yes (up regulated)
RALB |  | Yes
RAP1GAP (includes EG:5909) |  | Yes
RARRES1 |  | Yes
RBMS2 |  |  | Yes (down regulated)
RBP4 |  |  | Yes (down regulated) |  | Yes
[NAME] (includes EG:9978) |  |  |  | Yes
retinoic acid |  | Yes
RGL4 | Yes (up regulated) |  |  |  | Yes
RIPK4 |  |  |  | Yes
RNA polymerase II |  | Yes
RNASEL |  |  | Yes (down regulated) |  | Yes
[NAME] |  | Yes
RNF126 |  |  |  | Yes
RPS24 (includes EG:6229) |  |  | Yes (up regulated)
RPS27 |  | Yes
[NAME] |  |  | Yes (up regulated)
RUVBL2 |  | Yes
S100A2 |  |  | Yes (down regulated) |  | Yes
SCAMP1 |  |  |  | Yes
SERPINB8 | Yes (up regulated)
SFRP1 |  |  | Yes (up regulated) |  | Yes
SLC25A3 |  | Yes
SLC25A5 |  | Yes
SLC27A1 |  | Yes
SLC2A4 |  |  |  | Yes
SRC |  | Yes |  | Yes
ST3GAL1 |  |  | Yes (down regulated) |  | Yes
STARD10 | Yes (up regulated)
STARD9 | Yes (down regulated)
STK38L (includes EG:23012) |  | Yes
STMN4 |  |  | Yes (down regulated)
TAC4 |  |  | Yes (up regulated)
TACR1 |  |  |  | Yes
TAF1D |  |  | Yes (up regulated)
TAOK3 |  |  |  | Yes
[NAME] |  |  |  | Yes
testosterone |  |  |  | Yes
TGFB1 |  | Yes
thromboxane B2 |  | Yes
TIFA |  |  |  | Yes
[NAME] |  |  | Yes (down regulated)
TMED9 |  |  |  | Yes
TMSB10 | Yes (up regulated)
TNAP |  |  |  | Yes
TNF |  | Yes
Tnf receptor |  |  |  | Yes
TNFRSF11A |  |  |  | Yes
TNFRSF12A |  |  |  | Yes
[NAME] |  |  |  | Yes
TNFRSF19 |  |  |  | Yes
TNFRSF1A |  | Yes
TNFSF11 |  |  |  | Yes
[NAME] |  |  | Yes (up regulated)
TP53 |  |  |  | Yes
TRAF |  |  |  | Yes
TRAF1-TRAF2-TRAF3 |  |  |  | Yes
TRAF2 |  |  | Yes (down regulated) |  | Yes
TRAF3IP2 |  |  |  | Yes
TRAF6 |  | Yes |  | Yes
TRAIP |  |  |  | Yes
TRIM22 |  | Yes
TRIP6 |  |  |  | Yes
TRPC4AP |  |  |  | Yes
[NAME] |  |  | Yes (down regulated)
TUBB4 |  |  |  | Yes
TXNDC17 |  |  |  | Yes
UBC |  | Yes
UBD |  | Yes
UBE2 |  |  |  | Yes
UBE2D3 |  | Yes | Yes (up regulated)
UBE2L3 |  |  |  | Yes
UBE2N |  |  |  | Yes
UBE2V1 |  |  |  | Yes
UBL4A | Yes (up regulated)
VCL |  |  |  | Yes
VHL |  |  |  | Yes
WISP1 |  |  | Yes (up regulated) |  | Yes
ZBTB43 |  |  |  | Yes
ZNF232 |  |  | Yes (down regulated)
ZNF624 | Yes (down regulated)
ZRANB1 |  |  | Yes (up regulated)