Spreadsheet: 1428d131-2f18-469c-8c73-1c7ff110c1e3
Sheet: Sheet1

Supplemental table S3 - significant  pathways identified in Ingenuity populated by genes from whole blood as a function of the serial time points sampled. | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14 | Unnamed: 15 | Unnamed: 16 | Unnamed: 17 | Unnamed: 18 | Unnamed: 19 | Unnamed: 20 | Unnamed: 21 | Unnamed: 22 | Unnamed: 23 | Unnamed: 24 | Unnamed: 25 | Unnamed: 26 | Unnamed: 27 | Unnamed: 28 | Unnamed: 29 | Unnamed: 30 | Unnamed: 31 | Unnamed: 32 | Unnamed: 33 | Unnamed: 34 | Unnamed: 35 | Unnamed: 36 | Unnamed: 37 | Unnamed: 38 | Unnamed: 39 | Unnamed: 40
Ingenuity Canonical Pathways | AnalysisName | P-value | % populated | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules | Molecules
iCOS-iCOSL Signaling in T Helper Cells | Pre-Tx_vs_week 1 | 2.630267991895376e-08 | 23.1 | PIK3R1 | LCK | TRA@ | TRD@ | AKT3 | CAMK4 | PIK3C2B | IL2RB | PLCG1 | CD3D | PRKCQ | ZAP70 | CD28 | CD40LG | TRGV9 | ITPR3 | [NAME] | CD3E | [NAME] | NFATC2 | TRAT1 | CD247 | ICOS | LAT | PPP3CC
iCOS-iCOSL Signaling in T Helper Cells | Pre-Tx_vs_week 2 | 2.8840315031266e-06 | 19.4 | CD3G | PIK3R1 | TRA@ | LCK | TRD@ | AKT3 | ITPR3 | CAMK4 | PIK3C2B | [NAME] | PLCG1 | CD3E | [NAME] | CD3D | ZAP70 | PRKCQ | SHC1 | CD247 | ICOS | LAT | PPP3CC
iCOS-iCOSL Signaling in T Helper Cells | Pre-Tx_vs_week 4 | 9.332543007969905e-05 | 12 | LCK | TRA@ | CD40LG | CAMK4 | ITPR3 | [NAME] | NFATC1 | PLCG1 | CD3D | [NAME] | NFATC2 | ZAP70 | LAT
iCOS-iCOSL Signaling in T Helper Cells | Pre-Tx_vs_week 8 | 0.00331131121482591 | 8.33 | CD3G | LCK | PLCG1 | [NAME] | CD3D | NFATC2 | ZAP70 | LAT | [NAME]
T Cell Receptor Signaling | Pre-Tx_vs_week 1 | 2.630267991895376e-08 | 23.1 | PIK3R1 | TRA@ | LCK | CD8B | RASGRP1 | TXK | FYN | CD8A | CAMK4 | PIK3C2B | RRAS2 | CARD11 | PLCG1 | CD3E | [NAME] | CD3D | NFATC2 | ZAP70 | PRKCQ | CD247 | LAT | PPP3CC | CD28 | PTPN7
T Cell Receptor Signaling | Pre-Tx_vs_week 2 | 1.071519305237606e-05 | 19.2 | CD3G | PIK3R1 | TRA@ | LCK | CD8B | FYN | CAMK4 | PIK3C2B | HRAS | CARD11 | PLCG1 | CD3E | [NAME] | CD3D | ZAP70 | PRKCQ | CD247 | LAT | PPP3CC | PTPN7
T Cell Receptor Signaling | Pre-Tx_vs_week 4 | 0.000363078054770101 | 11.5 | NFATC1 | TRA@ | LCK | CARD11 | PLCG1 | [NAME] | CD3D | NFATC2 | ZAP70 | FYN | LAT | CAMK4
T Cell Receptor Signaling | Pre-Tx_vs_week 8 | 0.0008912509381337454 | 9.62 | CD3G | LCK | CARD11 | PLCG1 | [NAME] | CD3D | NFATC2 | ZAP70 | FYN | LAT
Natural Killer Cell Signaling | Pre-Tx_vs_week 1 | 4.897788193684456e-08 | 25.9 | PIK3R1 | LCK | PRKCH | KIR2DL5A | SH2D1A | [NAME] | AKT3 | CD244 | PIK3C2B | PLCG1 | [NAME] | ZAP70 | PRKCQ | SH2D1B | KIR2DL4 | KIR2DS2 | KIR3DL3 | KIR2DL1 | FYN | KLRC3 | KIR2DS5 | RRAS2 | KIR3DL2 | NCR3 | KIR2DL2 | KLRK1 | CD247 | LAT
Natural Killer Cell Signaling | Pre-Tx_vs_week 2 | 0.00154881661891248 | 14.8 | PIK3R1 | HCST | LCK | AKT3 | FYN | CD244 | PIK3C2B | HRAS | PLCG1 | [NAME] | ZAP70 | PRKCQ | SHC1 | KLRK1 | CD247 | LAT
Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells | Pre-Tx_vs_week 1 | 2.511886431509578e-07 | 42.9 | TRA@ | CYCS (includes EG:54205) | TRGV9 | [NAME] | CD3E | CD3D | PRF1 | BCL2 | TRD@ | CASP6 | CD247 | GZMB
Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells | Pre-Tx_vs_week 2 | 3.162277660168377e-06 | 35.7 | CD3G | TRA@ | CYCS (includes EG:54205) | CD3E | CD3D | PRF1 | BCL2 | TRD@ | CASP6 | CD247
Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells | Pre-Tx_vs_week 4 | 0.002290867652767772 | 17.9 | TRA@ | CYCS (includes EG:54205) | CD3D | PRF1 | CASP6
Cytotoxic T Lymphocyte-mediated Apoptosis of Target Cells | Pre-Tx_vs_week 8 | 0.006760829753919813 | 14.3 | CD3G | CYCS (includes EG:54205) | CD3D | CASP6
Calcium-induced T Lymphocyte Apoptosis | Pre-Tx_vs_week 1 | 5.888436553555874e-07 | 28.8 | TRA@ | LCK | PRKCH | TRGV9 | TRD@ | CAMK4 | ITPR3 | CAPN2 | PLCG1 | CD3E | [NAME] | CD3D | NFATC2 | PRKCQ | ZAP70 | CD247 | PPP3CC
Calcium-induced T Lymphocyte Apoptosis | Pre-Tx_vs_week 2 | 2.08929613085404e-05 | 23.7 | CD3G | LCK | TRA@ | TRD@ | CAMK4 | ITPR3 | PLCG1 | CD3E | [NAME] | CD3D | PRKCQ | ZAP70 | CD247 | PPP3CC
Calcium-induced T Lymphocyte Apoptosis | Pre-Tx_vs_week 4 | 0.000257039578276886 | 15.3 | TRA@ | LCK | PLCG1 | [NAME] | CD3D | NFATC2 | ZAP70 | ITPR3 | CAMK4
Calcium-induced T Lymphocyte Apoptosis | Pre-Tx_vs_week 8 | 0.001621810097358928 | 11.9 | CD3G | LCK | PLCG1 | [NAME] | CD3D | NFATC2 | ZAP70
CD28 Signaling in T Helper Cells | Pre-Tx_vs_week 1 | 1.047128548050897e-05 | 19.5 | PIK3R1 | TRA@ | LCK | TRGV9 | TRD@ | AKT3 | FYN | ITPR3 | CAMK4 | PIK3C2B | ARPC5L (includes EG:81873) | CARD11 | PLCG1 | CD3E | [NAME] | CD3D | NFATC2 | ZAP70 | PRKCQ | CD247 | LAT | PPP3CC | CD28
CD28 Signaling in T Helper Cells | Pre-Tx_vs_week 2 | 4.786300923226377e-05 | 17.8 | CD3G | PIK3R1 | TRA@ | LCK | TRD@ | AKT3 | FYN | ITPR3 | CAMK4 | PIK3C2B | ARPC5L (includes EG:81873) | CARD11 | PLCG1 | CD3E | [NAME] | CD3D | ZAP70 | PRKCQ | CD247 | LAT | PPP3CC
CD28 Signaling in T Helper Cells | Pre-Tx_vs_week 4 | 0.0002511886431509577 | 11.9 | LCK | TRA@ | FYN | CAMK4 | ITPR3 | NFATC1 | ARPC5L (includes EG:81873) | PLCG1 | CARD11 | [NAME] | CD3D | NFATC2 | ZAP70 | LAT
CD28 Signaling in T Helper Cells | Pre-Tx_vs_week 8 | 0.001862087136662866 | 9.32 | CD3G | ARPC5L (includes EG:81873) | LCK | CARD11 | PLCG1 | [NAME] | CD3D | NFATC2 | ZAP70 | FYN | LAT
[NAME] in Cytotoxic T Lymphocytes | Pre-Tx_vs_week 1 | 0.0001096478196143184 | 18.9 | PIK3R1 | TRA@ | LCK | TRGV9 | TRD@ | AKT3 | FYN | PIK3C2B | PLCG1 | CD3E | CD3D | ZAP70 | PPP2R2B | TRAT1 | CD247 | LAT | CD28
[NAME] in Cytotoxic T Lymphocytes | Pre-Tx_vs_week 2 | 0.0001412537544622754 | 17.8 | CD3G | PIK3R1 | TRA@ | LCK | PPP2R1B | TRD@ | AKT3 | FYN | PPP2R5C | PIK3C2B | PLCG1 | CD3E | CD3D | ZAP70 | CD247 | LAT
[NAME] in Cytotoxic T Lymphocytes | Pre-Tx_vs_week 4 | 0.01318256738556407 | 8.89 | TRA@ | LCK | PPP2R1B | PLCG1 | CD3D | ZAP70 | FYN | LAT
[NAME] in Cytotoxic T Lymphocytes | Pre-Tx_vs_week 8 | 0.0009549925860214355 | 10 | CD3G | LCK | PPP2R1B | PLCG1 | CD3D | ZAP70 | FYN | AP2A2 | LAT
[NAME] in Cytotoxic T Lymphocytes | Pre-Tx_vs_week 12 | 0.02089296130854039 | 7.78 | PPP2R1B | PLCG1 | ZAP70 | AKT2 | PPP2R5C | LAT | AP1G2
[NAME] in Macrophages | Pre-Tx_vs_week 1 | 0.0004365158322401656 | 17.9 | CCL4 | TRA@ | PRKCH | CCR5 | TRGV9 | TRD@ | CAMK4 | GNB1L | PLCG1 | CD3E | [NAME] | CD3D | PRKCQ | CD247
[NAME] in Macrophages | Pre-Tx_vs_week 2 | 0.001778279410038922 | 15.4 | CD3G | TRA@ | PLCG1 | CD3E | [NAME] | CD3D | TRD@ | PRKCQ | GNB2L1 | CD247 | CAMK4 | GNB1L
[NAME] in Macrophages | Pre-Tx_vs_week 4 | 0.04073802778041127 | 7.69 | TRA@ | PLCG1 | [NAME] | CD3D | CAMK4 | GNB1L
Aminoacyl-tRNA Biosynthesis | Pre-Tx_vs_week 1 | 0.000457088189614875 | 22.5 | EPRS | QARS | YARS | VARS | HARS | AARS2 | LARS | AARS | FARSB
Aminoacyl-tRNA Biosynthesis | Pre-Tx_vs_week 2 | 7.07945784384137e-05 | 27.5 | [NAME] | EPRS | QARS | YARS | VARS | HARS | AARS2 | LARS | FARSA | AARS | FARSB
Aminoacyl-tRNA Biosynthesis | Pre-Tx_vs_week 4 | 0.001258925411794166 | 17.5 | AARSD1 | EPRS | HARS | GARS | AARS2 | AARS | FARSB
Aminoacyl-tRNA Biosynthesis | Pre-Tx_vs_week 8 | 0.02951209226666384 | 12.5 | QARS | GARS | AARS2 | FARSA | FARSB
Aminoacyl-tRNA Biosynthesis | Pre-Tx_vs_week 12 | 0.03715352290971725 | 12.5 | VARS | HARS | GARS | AARS2 | FARSB
Pyrimidine Metabolism | Pre-Tx_vs_week 1 | 0.000602559586074357 | 17.1 | PRIM2 | RPUSD2 | ITPA | POLR1C | CAD | EIF2AK4 | NME3 | POLH | CTPS2 | TRUB1 | UCKL1 | UNG | POLR2H | POLR3A | POLD2 | PUS1 | DTYMK | NME2 | DCTD | POLG | TRUB2 | AK3 | POLRMT | POLR1B | NME1 | POLR1E
Pyrimidine Metabolism | Pre-Tx_vs_week 2 | 0.004466835921509628 | 14.5 | RPUSD4 | POLR2H | POLR3A | RPUSD2 | ITPA | POLR2I | POLD2 | CAD | POLR1C | PUS1 | ENTPD6 | NME2 | DTYMK | NME3 | POLG | TRUB2 | POLH | POLRMT | CTPS2 | PRIM1 | NME1 | POLR1E
Pyrimidine Metabolism | Pre-Tx_vs_week 12 | 0.03548133892335753 | 6.58 | POLR3A | POLD2 | POLA2 | POLR2F | POLR1C | POLR1E | ENTPD6 | POLE | TRUB2 | POLG
Purine Metabolism | Pre-Tx_vs_week 1 | 0.000602559586074357 | 11.8 | PRIM2 | ADSL | ITPA | PSMC2 | POLR1C | CASK | TRAP1 | NME3 | EIF2AK4 | POLH | AFG3L2 | RUVBL1 | GART | PAICS | CARD11 | APRT | MYO9A | POLR3A | POLR2H | POLD2 | PPAT | NME2 | POLG | AK3 | POLRMT | AK5 | ADA | PRPS1 | ATIC | POLR1B | IMPDH2 | FHIT | DDX39 | NME1 | DLG3 | POLR1E
Purine Metabolism | Pre-Tx_vs_week 2 | 9.549925860214353e-05 | 12.2 | ADSL | ITPA | POLR2I | POLR1C | CASK | GMPS | TRAP1 | ATP5G1 | RUVBL2 | NME3 | POLH | AFG3L2 | RUVBL1 | GART | PAICS | CARD11 | APRT | MYO9A | POLR3A | POLR2H | POLD2 | ENTPD6 | NME2 | POLG | POLRMT | AK5 | ADA | ATIC | PDE4A | IMPDH2 | PRIM1 | DDX39 | NME1 | DLG3 | POLR1E | ATP5G2 | PDE7A
Purine Metabolism | Pre-Tx_vs_week 8 | 0.02570395782768863 | 4.93 | PDE6B | POLR3A | POLR2I | ATP5G1 | NME3 | POLG | AFG3L2 | AK5 | RUVBL1 | PRPS1 | APRT | CARD11 | DLG3 | POLR1E | MYO9A
Purine Metabolism | Pre-Tx_vs_week 12 | 0.002884031503126604 | 6.25 | PDE6B | POLR3A | POLD2 | POLR1C | TRAP1 | ATP5G1 | ENTPD6 | POLG | POLE | AFG3L2 | AK5 | PRPS1 | CARD11 | FHIT | POLA2 | POLR2F | POLR1E | PDE7A | MYO9A
Role of NFAT in Regulation of the Immune Response | Pre-Tx_vs_week 1 | 0.0006760829753919812 | 13.7 | PIK3R1 | LCK | TRA@ | TRD@ | AKT3 | CAMK4 | PIK3C2B | PLCG1 | CD3D | PRKCQ | ZAP70 | CSNK1E | CD28 | TRGV9 | FYN | ITPR3 | GNB1L | RRAS2 | CD3E | [NAME] | RCAN3 | NFATC2 | CD247 | LAT | PPP3CC
Role of NFAT in Regulation of the Immune Response | Pre-Tx_vs_week 2 | 0.0008912509381337454 | 13.1 | CD3G | PIK3R1 | TRA@ | LCK | TRD@ | AKT3 | FYN | GNB2L1 | ITPR3 | CAMK4 | GNB1L | PIK3C2B | HRAS | PLCG1 | CD3E | [NAME] | RCAN3 | CD3D | ZAP70 | PRKCQ | CD247 | LAT | CSNK1E | PPP3CC
Role of NFAT in Regulation of the Immune Response | Pre-Tx_vs_week 4 | 0.004073802778041122 | 8.2 | TRA@ | LCK | FYN | CAMK4 | ITPR3 | GNB1L | NFATC1 | PLCG1 | [NAME] | CD3D | RCAN3 | NFATC2 | ZAP70 | CSNK1E | LAT
Role of NFAT in Regulation of the Immune Response | Pre-Tx_vs_week 8 | 0.03019951720402015 | 6.01 | CD3G | LCK | PLCG1 | [NAME] | CD3D | RCAN3 | NFATC2 | ZAP70 | FYN | LAT | CSNK1E
Glutamate Metabolism | Pre-Tx_vs_week 1 | 0.001659586907437561 | 21.6 | EPRS | QARS | GOT2 | PPAT | CAD | GLS | GNPNAT1 | GSS
Glutamate Metabolism | Pre-Tx_vs_week 2 | 0.001905460717963246 | 21.6 | EPRS | QARS | GOT2 | CAD | GMPS | GLS | GNPNAT1 | GSS
EIF2 Signaling | Pre-Tx_vs_week 1 | 0.00245470891568503 | 14.8 | EIF1AX | PIK3R1 | EIF2B3 | EIF2B4 | AKT3 | EIF3H | EIF2AK4 | EIF3B | PIK3C2B | EIF2B5 | RRAS2 | EIF3E | EIF3G
EIF2 Signaling | Pre-Tx_vs_week 2 | 0.04677351412871979 | 11.4 | EIF2B5 | PIK3R1 | HRAS | EIF2B4 | EIF3C | AKT3 | SHC1 | EIF3B | EIF3G | PIK3C2B
Non-Small Cell Lung Cancer Signaling | Pre-Tx_vs_week 1 | 0.004168693834703353 | 15.1 | PIK3R1 | RRAS2 | PLCG1 | CDK4 | CDK6 | FHIT | SIN3A | AKT3 | ERBB2 | ITPR3 | PIK3C2B
mTOR Signaling | Pre-Tx_vs_week 1 | 0.00758577575029183 | 12.1 | PIK3R1 | PRKCH | AKT3 | RHOH | EIF3H | EIF3B | GNB1L | PIK3C2B | RRAS2 | NAPEPLD | RPS6 | PRKCQ | PPP2R2B | RHOF | EIF3E | EIF3G | DDIT4
mTOR Signaling | Pre-Tx_vs_week 2 | 0.03801893963205611 | 10.7 | PIK3R1 | PPP2R1B | EIF3C | AKT3 | EIF3B | PPP2R5C | PIK3C2B | GNB1L | HRAS | NAPEPLD | RPS6 | PRKCQ | RHOF | EIF3G | DDIT4
Primary Immunodeficiency Signaling | Pre-Tx_vs_week 1 | 0.008912509381337455 | 16.1 | LCK | CD40LG | CD3D | ZAP70 | FYN | CD8A | TCF7 | UNG | ADA
Primary Immunodeficiency Signaling | Pre-Tx_vs_week 2 | 0.01023292992280754 | 16.1 | RFX5 | IGHG1 | LCK | CD3D | ZAP70 | SHC1 | FYN | TCF7 | ADA
Primary Immunodeficiency Signaling | Pre-Tx_vs_week 4 | 0.003981071705534972 | 12.5 | IGHG1 | LCK | CD40LG | CD3D | ZAP70 | FYN | TCF7
Primary Immunodeficiency Signaling | Pre-Tx_vs_week 8 | 0.005754399373371565 | 10.7 | IGHG1 | LCK | CD3D | ZAP70 | FYN | TCF7
Systemic Lupus Erythematosus Signaling | Pre-Tx_vs_week 1 | 0.01071519305237606 | 12.5 | PIK3R1 | TRA@ | LCK | CD40LG | TRGV9 | TRD@ | AKT3 | CAMK4 | PIK3C2B | RRAS2 | PLCG1 | CD3E | CD3D | NFATC2 | CD247 | LAT | CD28
Systemic Lupus Erythematosus Signaling | Pre-Tx_vs_week 2 | 0.02691534803926914 | 11 | CD3G | PIK3R1 | TRA@ | LCK | TRD@ | AKT3 | CAMK4 | PIK3C2B | HRAS | IGHG1 | PLCG1 | CD3E | CD3D | CD247 | LAT
Systemic Lupus Erythematosus Signaling | Pre-Tx_vs_week 4 | 0.008709635899560801 | 8.09 | NFATC1 | TRA@ | IGHG1 | LCK | CD40LG | PLCG1 | CD3D | NFATC2 | IGHG3 | LAT | CAMK4
Glioma Signaling | Pre-Tx_vs_week 1 | 0.01202264434617412 | 12.1 | PIK3R1 | PRKCH | CDK4 | CDK6 | AKT3 | PDGFD | CAMK4 | PIK3C2B | RRAS2 | PLCG1 | [NAME] | SIN3A | PRKCQ
Phenylalanine, [NAME] and Tryptophan Biosynthesis | Pre-Tx_vs_week 1 | 0.01584893192461112 | 23.5 | YARS | GOT2 | ENO2 | FARSB
Phenylalanine, [NAME] and Tryptophan Biosynthesis | Pre-Tx_vs_week 2 | 0.01698243652461743 | 29.4 | YARS | GOT2 | ENO2 | FARSA | FARSB
Phenylalanine, [NAME] and Tryptophan Biosynthesis | Pre-Tx_vs_week 4 | 0.01819700858609983 | 17.6 | PCBD2 | ENO2 | FARSB
Small Cell Lung Cancer Signaling | Pre-Tx_vs_week 1 | 0.01621810097358929 | 12.3 | PIK3R1 | CYCS (includes EG:54205) | CDK4 | CDK6 | FHIT | BCL2 | SIN3A | AKT3 | TRAF1 | PIK3C2B
Small Cell Lung Cancer Signaling | Pre-Tx_vs_week 2 | 0.04466835921509629 | 11.1 | PIK3R1 | SUV39H1 | CYCS (includes EG:54205) | CDK4 | BCL2 | PIAS3 | AKT3 | TRAF1 | PIK3C2B
Apoptosis Signaling | Pre-Tx_vs_week 1 | 0.02454708915685029 | 12.2 | PARP1 | CYCS (includes EG:54205) | RRAS2 | CAPN2 | PLCG1 | [NAME] | DIABLO | MAP3K14 | BCL2 | PRKCQ | CASP6
Ceramide Signaling | Pre-Tx_vs_week 1 | 0.02754228703338165 | 12.7 | PIK3R1 | CYCS (includes EG:54205) | RRAS2 | DIABLO | BCL2 | S1PR1 | AKT3 | S1PR5 | PPP2R2B | PIK3C2B
Alanine and Aspartate Metabolism | Pre-Tx_vs_week 1 | 0.02884031503126605 | 16.7 | ASS1 | ADSL | GOT2 | CAD | AARS2 | ASNS | AARS
Alanine and Aspartate Metabolism | Pre-Tx_vs_week 2 | 0.00933254300796991 | 19 | ASS1 | [NAME] | ADSL | GOT2 | CAD | AARS2 | ASNS | AARS
Lipid Antigen Presentation by CD1 | Pre-Tx_vs_week 1 | 0.03019951720402015 | 23.8 | TRA@ | TRGV9 | CD3E | TRD@ | CD1C
Allograft Rejection Signaling | Pre-Tx_vs_week 1 | 0.03311311214825911 | 17.9 | TRA@ | CD40LG | TRGV9 | PRF1 | TRD@ | GZMB | CD28
Allograft Rejection Signaling | Pre-Tx_vs_week 4 | 0.01148153621496883 | 12.8 | TRA@ | IGHG1 | CD40LG | PRF1 | IGHG3
Crosstalk between Dendritic Cells and Natural Killer Cells | Pre-Tx_vs_week 1 | 0.03388441561392025 | 15.1 | KIR2DL4 | CD40LG | KIR2DL5A | KIR3DL3 | KIR2DL1 | [NAME] | CCR7 | IL2RB | PRF1 | KIR3DL2 | NCR3 | KIR2DL2 | KLRK1 | CD28
Tyrosine Metabolism | Pre-Tx_vs_week 1 | 0.03801893963205611 | 11.4 | GOT2 | MIF | DBT | MGMT | EDF1 | ADHFE1 | ADH5 (includes EG:128) | [NAME]
Autoimmune Thyroid Disease Signaling | Pre-Tx_vs_week 1 | 0.04168693834703353 | 17.1 | TRA@ | CD40LG | TRGV9 | PRF1 | TRD@ | GZMB | CD28
Autoimmune Thyroid Disease Signaling | Pre-Tx_vs_week 4 | 0.01445439770745927 | 12.2 | TRA@ | IGHG1 | CD40LG | PRF1 | IGHG3
One Carbon Pool by Folate | Pre-Tx_vs_week 1 | 0.04365158322401658 | 18.2 | ATIC | GART | MTR | SHMT2
One Carbon Pool by Folate | Pre-Tx_vs_week 2 | 0.01047128548050899 | 22.7 | ATIC | GART | MTR | AMT (includes EG:275) | SHMT2
One Carbon Pool by Folate | Pre-Tx_vs_week 4 | 0.03981071705534973 | 13.6 | ATIC | AMT (includes EG:275) | MTHFD1
Ubiquinone Biosynthesis | Pre-Tx_vs_week 2 | 4.786300923226377e-05 | 23.9 | NDUFB7 | NDUFA11 | METTL6 | NDUFS8 | [NAME] | NDUFB8 | FTSJ2 | NDUFA9 (includes EG:4704) | METTL2B | MGMT | NDUFB11 | EDF1 | NDUFB9 | NDUFV1 | NDUFS3 | NDUFB2 | NDUFS6 (includes EG:4726)
Ubiquinone Biosynthesis | Pre-Tx_vs_week 8 | 0.01047128548050899 | 8.45 | NDUFB8 | NDUFA7 | NDUFB7 | NDUFA11 | EDF1 | NDUFS5
Selenoamino Acid Metabolism | Pre-Tx_vs_week 2 | 0.01584893192461112 | 23.7 | SEPHS1 | FTSJ2 | MAT2A | GGT7 | METTL6 | METTL2B | MGMT | EDF1 | [NAME]
G Protein Signaling Mediated by [NAME] | Pre-Tx_vs_week 4 | 0.02951209226666384 | 11.4 | LCK | PLCG1 | ABL1 | GNB1L
DNA Methylation and Transcriptional Repression Signaling | Pre-Tx_vs_week 12 | 0.02884031503126605 | 13 | MBD3 (includes EG:53615) | CHD4 | CHD3
N-Glycan Degradation | Pre-Tx_vs_week 12 | 0.03235936569296281 | 10.3 | MAN1C1 | MAN1B1 | HEXA
Mitochondrial Dysfunction | Pre-Tx_vs_week 2 | 0.03235936569296281 | 11.6 | NDUFB7 | CYCS (includes EG:54205) | NDUFA11 | NDUFS8 | COX4I1 | NDUFB8 | HSD17B10 | NDUFA9 (includes EG:4704) | NDUFB11 | NDUFB9 | NDUFV1 | NDUFS3 | GPX7 | NDUFB2 | NDUFS6 (includes EG:4726)
Cleavage and Polyadenylation of Pre-mRNA | Pre-Tx_vs_week 8 | 0.04365158322401658 | 16.7 | PABPN1 | CPSF1