Spreadsheet: 05a3c2b0-7fb9-45ec-86b6-0d9736272f33
Sheet: Sheet1

Table S3. Cantharidin-specific genetic interactors of CRG1.
ORF | GENE | single pool | double pool | p val, dmso vs drug | p val, single vs double | MDR | Biological Process
YNR006W | VPS27 | -0.025232000586276 | -3.058791796731559 | 0.02314605429095115 | 1.316949783178459e-06 | MDR
YOL064C | MET22 | 0.102749502403871 | -2.621191309999733 | 0.001113202712907546 | 0.001761300975201579 | cantharidin-specific
YOR153W | PDR5 | 0.0201655202348061 | -2.404357957255917 | 0.00142734670151662 | 3.821310475659224e-06 | cantharidin-specific
[NAME] | ERV14 | -0.00224653229040256 | -2.377743394697754 | 0.0007061522580382799 | 1.082593619361202e-05 | MDR
YDR080W | VPS41 | 0.448388181981662 | -2.367158580107317 | 0.04910059855132304 | 0.00671893643919727 | MDR
YHR030C | SLT2 | 0.0440634214406207 | -2.150365659584537 | 0.0004639507744974705 | 2.55554757044877e-07 | MDR
YIL084C | SDS3 | 0.0341939864505334 | -2.05113081156618 | 0.01229535701014801 | 0.0004180145674790351 | cantharidin-specific
YKL041W | VPS24 | -0.202897121174328 | -1.852846870455779 | 0.004602591851797357 | 0.0006615148755797234 | MDR
YMR073C | IRC21 | 0.23864362537405 | -1.7607575211495 | 0.001152531736527696 | 4.613140550938643e-05 | cantharidin-specific
YAL013W | DEP1 | 0.242645877810544 | -1.707515684102658 | 0.01280332777553282 | 0.00127610292069407 | cantharidin-specific | [NAME] process
YLL043W | FPS1 | 0.447691197010232 | -1.701290862808408 | 0.009679229529018549 | 0.0004601338304757896 | cantharidin-specific
YDL074C | BRE1 | -0.234081134129465 | -1.679018148235573 | 0.01308638801915301 | 3.646215046231239e-05 | MDR
YDL006W | PTC1 | 0.14353870975759 | -1.654778445684849 | 0.02045841325041101 | 0.01161546308372808 | cantharidin-specific
YOR001W | [NAME] | -0.0531807931331396 | -1.624261658151786 | 0.002607267407781136 | 0.0180305670433666 | cantharidin-specific
YNL171C | YNL171C | 0.244338594580097 | -1.621864228490421 | 0.005474913422659233 | 0.0003078495161664654 | cantharidin-specific
YIL153W | RRD1 | 0.0835067744645995 | -1.559339264625005 | 0.01895679428734893 | 1.136448251622411e-05 | MDR
YDR435C | PPM1 | -0.0236371495421499 | -1.558342133720594 | 0.01718955490012352 | 0.00301041992342976 | MDR
YDR388W | RVS167 | -0.526441797863651 | -1.500832998268551 | 0.006143012134036461 | 0.02114132489622438 | cantharidin-specific | [NAME] process
[NAME] | VPS51 | 0.0170866945886851 | -1.498679715037335 | 0.005598351837397905 | 0.0002627060391581282 | cantharidin-specific
YDL020C | RPN4 | 0.369294677789183 | -1.477403427357824 | 0.01438647478169946 | 0.0003928213830025507 | cantharidin-specific
YPL055C | LGE1 | -0.215670217165143 | -1.469836938673105 | 0.0006174250826370762 | 0.001433094319275827 | MDR
[NAME] | [NAME] | -0.0854444246870206 | -1.45989540273018 | 0.0004867392257491468 | 0.001036955780741629 | cantharidin-specific
YKL212W | SAC1 | 0.0883527272668344 | -1.450982341585092 | 0.04403152969487024 | 0.02479883535511294 | cantharidin-specific | [NAME] process
YJR073C | OPI3 | -0.049647362056342 | -1.382061049409553 | 0.05022206119345253 | 0.02223673115079619 | MDR | [NAME] process
YGL124C | MON1 | 0.0707272003574515 | -1.346423395055374 | 0.01295510400360776 | 0.004428130001369922 | MDR
YML097C | VPS9 | 0.851514238861081 | -1.336575596133002 | 0.01266039887734287 | 0.009069474836083535 | MDR
YDR334W | SWR1 | 0.0385957971757729 | -1.321703494442073 | 0.01032479710107614 | 2.487772936450324e-05 | MDR
YLR039C | RIC1 | -0.0459549680354371 | -1.314125813875362 | 0.003912413029889048 | 0.008139040092587244 | cantharidin-specific
YGR157W | CHO2 | 0.12073518999327 | -1.290951915220271 | 0.004321948611038065 | 0.008222274075615559 | cantharidin-specific | [NAME] process
YLR085C | ARP6 | 0.0690615246098935 | -1.274184276896112 | 0.001642066783002489 | 0.000639394017848957 | MDR
YDR369C | XRS2 | 0.54077123496314 | -1.226513791360706 | 0.006090541414535483 | 0.00802895650116893 | cantharidin-specific
YLR044C | PDC1 | 0.12475134298727 | -1.221375146796873 | 0.006211420797060725 | 0.004765467700865178 | cantharidin-specific
YPR066W | UBA3 | 0.0940323313959191 | -1.204367633692948 | 0.008030541075301764 | 0.01933801013632592 | cantharidin-specific
YOL012C | HTZ1 | -0.0514334352776212 | -1.201336147752693 | 0.01942494938357797 | 0.0001286415141329456 | cantharidin-specific
YGL084C | GUP1 | 0.161471767515395 | -1.185549918247131 | 0.0006459417878589902 | 2.306267654521349e-07 | cantharidin-specific | [NAME] process
[NAME] | RPA34 | 0.071846820564143 | -1.182839331422916 | 0.005987704194857077 | 0.0002911011477123985 | cantharidin-specific
YHR041C | [NAME] | 0.0312674892075609 | -1.171216306022169 | 0.01963787659816099 | 1.399354190948463e-05 | cantharidin-specific
[NAME] | [NAME] | 0.0846419705810604 | -1.150345757415531 | 0.00194467718959112 | 0.001304055913166067 | cantharidin-specific | [NAME] process
YDR485C | VPS72 | 0.209785776471019 | -1.132137375554003 | 0.005538074284776979 | 0.0008385994451740697 | MDR
YDR108W | GSG1 | 0.22862228442901 | -1.125389953423721 | 0.01872170638962961 | 0.006947732580526274 | MDR
[NAME] | YTA7 | 0.0530039506504755 | -1.111674129472979 | 0.0001674948548061712 | 0.0004964047756348089 | MDR | [NAME] process
YJR118C | ILM1 | 0.167013538434992 | -1.106069473733067 | 0.003670757959840678 | 0.01271716753115933 | cantharidin-specific
YDR289C | RTT103 | -0.0297912288697309 | -1.103312093064893 | 0.01988327546176759 | 1.912242046716857e-05 | MDR
YGL148W | ARO2 | 0.20110295111152 | -1.099676572708231 | 0.007805635960162829 | 0.002135584447292455 | MDR
YMR263W | SAP30 | -0.00389661679871094 | -1.077714634890286 | 0.007756448392647107 | 0.0142348327284653 | MDR
YDL130W | RPP1B | 0.586459696703171 | -1.034883847373414 | 0.02379667918086952 | 0.007811043721806331 | cantharidin-specific
YNL294C | RIM21 | -0.131743890398773 | -1.03058043459699 | 0.0005496444984139268 | 0.00369464406358989 | MDR
YCR044C | [NAME] | 0.869743484678659 | -1.017836496875894 | 0.009665054376704939 | 0.000905585845448154 | cantharidin-specific | [NAME] process
YML001W | YPT7 | 0.123574128329181 | -1.010658243504523 | 0.03020064217677686 | 0.001992609299162002 | MDR
[NAME] | MED1 | -0.0894590061088544 | -1.004421579804959 | 0.01422487772578905 | 0.001748106108121252 | cantharidin-specific
YLR119W | SRN2 | 0.365657694790997 | -0.978663702710558 | 0.007128790964272577 | 0.0005862623395654869 | MDR
YLR242C | ARV1 | 0.485247579310049 | -0.96760535127361 | 0.03873855999264122 | 0.003157529806403012 | cantharidin-specific | [NAME] process
YMR224C | MRE11 | 0.019823272702081 | -0.967161342122513 | 0.003608320328035358 | 0.007588435813353699 | cantharidin-specific
YPL262W | FUM1 | 0.124643992585847 | -0.96354798763935 | 0.02784891888919436 | 0.00372851309324147 | MDR
YML041C | VPS71 | -0.297996342004007 | -0.9556679191365 | 0.002246723842744935 | 0.01889519530608591 | MDR
[NAME] | VPS35 | 0.306331724771187 | -0.939138929563905 | 0.03153176898416474 | 0.0001689827867429936 | MDR
[NAME] | [NAME] | 0.372672071148322 | -0.932652677983948 | 0.01208908174720297 | 0.002655994741152618 | cantharidin-specific
YPL178W | CBC2 | 0.0678622971251938 | -0.93043136737669 | 0.03215409874203016 | 0.009666665436938194 | cantharidin-specific
YJL124C | LSM1 | -0.181100278799658 | -0.929482810169215 | 0.002718225133373543 | 0.01089040972448153 | cantharidin-specific
YML008C | ERG6 | 0.216540543399249 | -0.899575784156348 | 0.01145243363308741 | 0.0008951901687809466 | cantharidin-specific | [NAME] process
YPR173C | VPS4 | 0.0114898548624091 | -0.892554558407842 | 0.02566630513917699 | 0.009725191606069777 | MDR
YBR126C | TPS1 | -0.0694858676020353 | -0.887391159028555 | 0.02056769935577676 | 0.004106451383459333 | cantharidin-specific
[NAME] | VPS75 | 0.0566105291159771 | -0.883188006031746 | 0.02706849050855588 | 0.004271681560187631 | cantharidin-specific
YHL033C | RPL8A | 0.184709328541079 | -0.875763644847952 | 0.00472739512455232 | 0.0003483946084328838 | cantharidin-specific
YOR243C | PUS7 | 0.153648957659566 | -0.862761142251385 | 0.006671733742159093 | 8.433086733496068e-05 | cantharidin-specific
YML071C | COG8 | -0.130709206486434 | -0.85595509526176 | 0.00851905240298589 | 0.01044401678546614 | MDR
YDR431W | YDR431W | 0.0365529865949611 | -0.854103105027641 | 0.00790577941438277 | 0.009405724513368626 | cantharidin-specific
[NAME] | RPL42A | 0.262039347682398 | 1.060573800072396 | 0.0002064144804181743 | 0.02420565131550026 | cantharidin-specific
YGR092W | DBF2 | 0.567194909188961 | 1.119295548964151 | 0.0004080089283432929 | 0.01263947442166774 | MDR
YKL006W | [NAME] | 0.111142324264666 | 1.275187396408054 | 0.0356620344156507 | 0.000418580467388012 | cantharidin-specific