Spreadsheet: 09e4bc5b-f967-4679-8b79-d7e47ea5b7a3
Sheet: Sheet1

Unnamed: 0 | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14 | Unnamed: 15
Supplementary Table 1:  Gene identification numbers for D.simulans and D. melanogaster. D.melanogaster CG and FB gene identification numbers; Function of predicted proteins; Secretion Signal prediction; [NAME] region prediction; Pairwise dN/dS; PAML data; Presence of orthologs in 12 genomes
 |  |  |  |  |  |  |  |  | M0 vs M3 |  | M1 vs M2 |  | M7 vs. M8
D.sim ID | D.mel id | D.mel CG | D.mel FBgn | Function1 | SP2 | TM3 | dN/dS4 | PAML Species5 | ps6 | dN/dS7 | ps8 | dN/dS9 | ps10 | dN/dS11 | 12 Genome Species12
dsim_GLEANR_16371 | CG2233-PA | CG2233 | FBgn0029131 | Unknown | X |  | 0.9513 | M,S,Sc,Y,E | 0.02 | 33.31*** | 0.18 | 4.16*** | 0.17 | 4.37*** | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,P | 0.23 | 2.64*** | 0.1 | 4.18*** | 0.17 | 3.10***
dsim_GLEANR_3734 | CG3066-PA | CG3066 | FBgn0042186 | [NAME] | X |  | 0.1693 | M,S,Sc,Y,E | 0.09 | 1.45*** | 0.09 | 1.45101 | 0.09163 | 1.46 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.03 | 2.56*** | 0.04 | 1 | 0.02 | 2.83*
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.03 | 2.63*** | 0.12672 | 1 | 0.02 | 2.90976
dsim_GLEANR_9093 | CG3831-PA | CG3831 | FBgn0033134 | Unknown |  | X | 0.3218 | M,S,Sc,Y,E | 0.14 | 1.54*** | 0.14242 | 1.54053 | 0.14242 | 1.54052 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.23 | 0.39*** | 0.01 | 1 | 0 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.34 | 0.20*** | 0 | 33.1334 | 0 | 1
dsim_GLEANR_7778 | Syx5-PA | CG4214 | FBgn0033906 | Nerve signaling |  | X | 0.3563 | M,S,Sc,Y,E | 0.31 | 0.54*** | 0.07365 | 1 | 0 | 1 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.3 | 0.34*** | 0.04 | 1 | 0 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.19 | 0.46*** | 0 | 17.20229 | 0 | 1
dsim_GLEANR_8979 | tsr-PA | CG4254 | FBgn0011726 | Actin metabolism |  |  | 0 | M,S,Sc,Y,E | 0.25 | 0 | 0 | 1 | 0 | 1.51524 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.16 | 0 | 0 | 1 | 0 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.02 | 0.90** | 0.00349 | 1 | 0.01666 | 1
dsim_GLEANR_2206 | Irk2-PB | CG4370 | FBgn0050197 | Cation transport |  | X | 0.0135 | M,S,Sc,Y,E | 0.09 | 1.56*** | 0.08606 | 1.55875 | 0.08607 | 1.55874 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.07 | 1.85*** | 0.04 | 2.21 | 0.07 | 1.78
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.04 | 2.23*** | 0.0049 | 5.25948 | 0.02737 | 2.85222
[NAME] | me31B-PA | CG4916 | FBgn0024733 | Helicase |  |  | 0.0454 | M,S,Sc,Y,E | 0.01 | 2.91569 | 0.00645 | 2.91571 | 0.01 | 2.91536 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.02 | 0.82*** | 0.00186 | 1 | 0.02 | 1.00*
dsim_GLEANR_2360 | DppIII-PB | CG7415 | FBgn0037580 | Peptidase |  | X | 0.0081 | M,S,Sc,Y,E | 0.002 | 2.92463 | 0.00193 | 2.9246 | 0.002 | 2.9263 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.06 | 0.67*** | 0 | 18.57 | 0.04 | 1.00*
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.1 | 0.44*** | 0 | 1 | 0 | 1.94784
dsim_GLEANR_10797 | Ef1alpha48D-PA | CG8280 | FBgn0037199 | Translation |  |  | 0.0189 | M,S,Sc,Y,E | 0.003 | 11.54*** | 0.00263 | 11.53825 | 0.002 | 11.54* | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.01 | 2.11*** | 0.01 | 2.11 | 0.01 | 2.11*
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.01 | 3.44*** | 0.01 | 3.27* | 0.01 | 3.42***
dsim_GLEANR_11000 | CG8331-PA | CG8331 | FBgn0010223 | Cell communication |  | X | 0.1903 | M,S,Sc,Y,E | 0.01 | 33.67*** | 0.01034 | 34.34917 | 0.01086 | 33.74055 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.01 | 30.56*** | 0.08 | 1 | 0.01 | 30.61*
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.21 | 0.59*** | 0.01044 | 35.51699 | 0.01 | 30.11**
dsim_GLEANR_11526 | Treh-PC | CG9364 | FBgn0035678 | Sugar metabolism | X |  | 0.1159 | M,S,Sc,Y,E | 0.05 | 2.95*** | 0.04 | 3.11*** | 0.05 | 2.93*** | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.04 | 3.36*** | 0.02 | 5.51*** | 0.03 | 3.75***
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.05 | 2.47*** | 0.01 | 5.43697 | 0.03 | 2.93***
dsim_GLEANR_11514 | Act57B-PA | CG10067 | FBgn0052068 | Actin formation |  |  | 0 | M,S,Y,E,A | 0.41 | 0 | 0 | 1 | 0 | 1 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Y,E,A,P | 0.37 | 0 | 0 | 1 | 0 | 1
dsim_GLEANR_13207 | CG10469-PA | CG10469 | FBgn0052834 | [NAME] | X |  | 0.069 | M,S,Sc,Y,E | 0.11 | 0.97209 | 0.04489 | 1 | 0.10034 | 1 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.25 | 0.56*** | 0.02 | 1 | 0.05 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.21 | 0.64*** | 0.04 | 1 | 0.11 | 1
dsim_GLEANR_5555 | CG10650-PA | CG10650 | FBgn0050371 | Peptidase | X |  | 0.5486 | M,S,Sc,Y,A | 0.11 | 2.94*** | 0.03 | 4.93 | 0.06 | 3.67* | M,S,Sc,Y,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,A,P | 0.09 | 2.97*** | 0.02732 | 5.36075 | 0.05 | 3.81**
dsim_GLEANR_13789 | Drs-PA | CG10810 | FBgn0010381 | Antimicrobial defense | X |  | 0 | M,S,Sc,Y,E | 0.46 | 0.02719 | 0 | 1 | 0 | 1 | M,S,Sc,Y,E,A,P,Pr,Mj
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.32 | 0.10112 | 0 | 23.07317 | 0 | 1
dsim_GLEANR_12120 | CG11137-PA | CG11137 | FBgn0029990 | Unknown |  | X | 0.0969 | M,S,Sc,Y,E | 0.15 | 0.24287 | 0.01026 | 1 | 0 | 1 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.01 | 1.80* | 0 | 25.23 | 0.01 | 1.80*
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.02 | 0.84*** | 0.00885 | 1 | 0.02 | 1.00*
dsim_GLEANR_9282 | CG11200-PA | CG11200 | FBgn0052702 | Dehydrogenase | X |  | 0.0173 | M,S,Sc,Y,E | 0.18 | 0.41117 | 0.03772 | 1 | 0 | 1 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.26 | 0.18* | 0 | 36.19 | 0 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.06 | 0.36*** | 0 | 7.37165 | 0 | 1
dsim_GLEANR_12517 | Galpha73B-PA | CG12232 | FBgn0039081 | Cell communication |  |  | 0.0492 | M,S,Sc,Y,E | 0.09 | 0.47*** | 0.01962 | 1 | 0 | 2.31789 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.002 | 9.65*** | 0.001 | 10.22 | 0.002 | 9.66
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.03 | 0.79*** | 0.00146 | 10.79118 | 0.00224 | 10.23634
dsim_GLEANR_9897 | etaTry-PA | CG12386 | [NAME] | [NAME] | X |  | 0.1419 | M,S,Sc,Y,E | 0.05 | 2.35*** | 0.06033 | 2.08778 | 0.05025 | 2.30556 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.03 | 3.02*** | 0.01 | 3.74 | 0.03 | 3.26*
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.03 | 2.69*** | 0.06981 | 1 | 0.03 | 2.65*
dsim_GLEANR_10438 | Tsp42El-PA | CG12840 | FBgn0039045 | Cell communication |  | X | 0.2498 | M,S,Sc,Y,E | 0.005 | 14.33* | 0.00366 | 14.19293 | 0.0043 | 14.22338 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.01 | 3.83*** | 0.05 | 1 | 0.02 | 3.65
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.15 | 0.68*** | 0.02942 | 1 | 0.0773 | 1
dsim_GLEANR_9414 | CG14495-PA | CG14495 | FBgn0034293 | Unknown |  |  | 0.0918 | M,S,Sc,Y,E | 0.09 | 1.56*** | 0.08606 | 1.55876 | 0.08607 | 1.55874 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.18 | 0.81*** | 0.07 | 1 | 0.13 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.01 | 2.66*** | 0 | 16.63037 | 0.00262 | 3.179
dsim_GLEANR_9351 | CG15098-PA | CG15098 | FBgn0037580 | Unknown |  | X | 0.6923 | M,S,Sc,Y,E | 0.02 | 4.63*** | 0.03732 | 3.83525 | 0.05093 | 3.22883 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.09 | 2.77*** | 0.04 | 3.66 | 0.07 | 3.00*
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.09 | 2.72*** | 0.04669 | 3.45989 | 0.08 | 2.89***
dsim_GLEANR_9344 | Jheh3-PA | CG15106 | FBgn0034406 | Juv. Horm. Catabolism | X | X | 0.0628 | M,S,Sc,Y,E | 0.15 | 0.48*** | 0.03056 | 1 | 0 | 1 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.19 | 0.37*** | 0 | 38.74 | 0.01 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.15 | 0.22*** | 0.03084 | 1 | 0.00079 | 1.46878
dsim_GLEANR_5780 | CG15293-PA | CG15293 | FBgn0051343 | Unknown | X |  | 0.4932 | M,S,Sc,Y,E | 0.2 | 1.42*** | 0.06727 | 1.69386 | 0.49375 | 1.15163 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.08 | 2.29*** | 0.04 | 1 | 0.03 | 2.82
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.07 | 2.32*** | 0.14805 | 1 | 0.05152 | 2.41212
dsim_GLEANR_5271 | CG15533-PA | CG15533 | FBgn0053306 | Phospholipid metabolism | X | X | 0.1327 | M,S,Sc,Y,E | 0.19 | 0.47*** | 0.04584 | 1 | 0 | 1 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.19 | 0.47*** | 0 | 21.49 | 0 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.01 | 1.08*** | 0.01158 | 1 | 0.00024 | 1.11034
dsim_GLEANR_6593 | CG17012-PA | CG17012 | FBgn0051686 | [NAME] | X |  | 0.893 | M,S,Sc,A | 0.07 | 6.08*** | 0.05 | 8.21*** | 0.06 | 6.96*** | M,S,Sc,A,V
dsim_GLEANR_2235 | CG17119-PA | CG17119 | FBgn0042187 | Amino acid transport | X | X | 0.067 | M,S,Sc,Y,E | 0.04 | 1.54*** | 0.04265 | 1.54328 | 0.04203 | 1.55205 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.08 | 1.02*** | 0 | 0.03 | 0.07 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.08 | 0.98*** | 0 | 2.4447 | 0.05822 | 1.06251
dsim_GLEANR_6882 | CG17234-PA | CG17234 | FBgn0004419 | [NAME] | X |  | 0.7435 | M,S,Sc,Y,E | 0.05 | 7.23*** | 0.09 | 5.25*** | 0.1 | 4.86*** | M,S,Sc,Y,E,P,Pr
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,P | 0.06 | 5.94*** | 0.1 | 4.20*** | 0.2 | 2.82***
dsim_GLEANR_6595 | CG17239-PA | CG17239 | FBgn0042186 | [NAME] | X |  | 0.7261 | M,S,Sc,Y,E | 0.22 | 2.40*** | 0.22 | 2.41* | 0.22 | 2.40* | M,S,Sc,Y,E,A,Pr,V
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.16 | 2.71*** | 0.09 | 3.41*** | 0.13 | 2.94***
dsim_GLEANR_6596 | Ser12-PA | CG17240 | FBgn0011708 | [NAME] | X |  | 0.6427 | M,S,Y,E | 0.09 | 6.27*** | 0.09 | 6.25*** | 0.09 | 6.25*** | M,S,Y,E
dsim_GLEANR_12116 | Qm-PA | CG17521 | FBgn0024733 | Translation |  |  | 0.0191 | M,S,Sc,Y,E | 0.005 | 2.77** | 0.00506 | 2.77493 | 0.001 | 2.78* | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.005 | 3.25*** | 0.005 | 3.25 | 0.005 | 3.25**
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.01 | 1.75*** | 0.00031 | 1.68866 | 0.005 | 1.75*
dsim_GLEANR_5775 | CG18125-PA | CG18125 | FBgn0011726 | [NAME] | X |  | 0.786 |  |  |  |  |  |  |  | M,S,Sc
dsim_GLEANR_11034 | CG30197-PA | CG30197 | FBgn0050197 | Unknown | X |  | 0.0496 | M,S,Sc,Y,E | 0.02 | 4.37*** | 0.0192 | 4.36663 | 0.002 | 4.37* | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.22 | 0.28* | 0.004 | 1 | 0 | 2.9
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.33 | 0.16482 | 0.00419 | 1 | 0.004 | 4.25754
dsim_GLEANR_15401 | CG30371-PA | CG30371 | FBgn0034500 | [NAME] | X |  | 0.1295 | M,S,Sc,Y,E | 0.36 | 0.48* | 0.05096 | 1 | 1.0459 | 1 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.02 | 1.35*** | 0.04 | 1 | 0.003 | 1.57
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.02 | 1.40*** | 0 | 27.5898 | 0.00899 | 1.74778
dsim_GLEANR_4658 | CG31343-PA | CG31343 | FBgn0051343 | Peptidase |  | X | 0.1365 | M,S,Sc,Y,E | 0.13 | 1.11*** | 0.12527 | 1.11197 | 0.12309 | 1.12055 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.06 | 1.32*** | 0.19 | 1 | 0.02 | 1.91
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.04 | 1.37*** | 0.04363 | 1 | 0.01164 | 2.01978
dsim_GLEANR_18113 | CG31681-PA | CG31681 | FBgn0034406 | [NAME] | X |  | 0.8207 | M,S,Y,E | 0.09 | 5.57*** | 0.08 | 6.05*** | 0.09 | 5.84*** | M,S,Sc,Y,E
dsim_GLEANR_6881 | CG31686-PA | CG31686 | FBgn0034398 | Unknown |  |  | 0.6606 |  |  |  |  |  |  |  | M,S,Sc,Y,E
dsim_GLEANR_14267 | CG32068-PA | CG32068 | FBgn0034293 | Secondary metabolism |  |  | 0.3911 | M,S,Sc,Y,E | 0.08 | 1.18*** | 0.08301 | 1.18365 | 0.08291 | 1.18364 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.02 | 0.92*** | 0.01 | 1 | 0 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.33 | 0.20*** | 0 | 5.31733 | 0.00112 | 1.22514
dsim_GLEANR_17130 | CG32702-PA | CG32072 | [NAME] | Protein-protein interact. |  |  | 0.1027 | M,S,Sc,Y,E | 0.02 | 2.55*** | 0.00271 | 6.09457 | 0.01 | 3.58** | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,P | 0.06 | 1.41** | 0.04592 | 1 | 0.03 | 2.11***
dsim_GLEANR_15288 | CG32834-PA | CG32834 | FBgn0052834 | [NAME] | X |  | 0.1874 | M,S,Sc,Y,E | 0.21 | 1.76*** | 0.20632 | 1.76396 | 0.20461 | 1.77092 | M,S,Sc,Y,E,A,P,Pr
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.08 | 2.75*** | 0.02 | 4.94 | 0.04 | 3.47
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.09 | 2.74*** | 0.02314 | 5.15209 | 0.06 | 3.25*
dsim_GLEANR_10398 | debcl-PA | CG33134 | FBgn0051343 | Apoptosis | X | X | 0.063 | M,S,Sc,Y,E | 0.06 | 0.97327 | 0.0345 | 1 | 0.05924 | 1 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.064 | 0.86*** | 0 | 28.21 | 0.06 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.06 | 0.71*** | 0 | 2.11299 | 0.04314 | 1
dsim_GLEANR_5795 | CG33306-PA | CG33306 | FBgn0003748 | Unknown | X |  | 0.0413 | M,S,Sc,Y,E | 0.27 | 0.47 | 0.03439 | 1 | 0 | 1 | M,S,Sc,Y,E,A,P,Pr,W,Mj,V,G
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A | 0.11 | 0.74*** | 0.053 | 1 | 0.03 | 1
 |  |  |  |  |  |  |  | M,S,Sc,Y,E,A,P | 0.37 | 0.40*** | 0.05 | 1 | 0.02 | 1.75
dsim_GLEANR_15604 | no mel
dsim_GLEANR_6594 | no mel
1Predicted protein function; 2"X" indiates that the proteins has a predicted secretion signal;3"X" indicates the proteins has a predicted transmembrane region;4dN/dS: pairwise comparison of D. melanogaster and D. simulans sequences, estimated assuming no rate heterogeneity; 5Species of Drosophila from which sequences were obtained for PAML analysis M= melanogaster, S = simulans, Sc= sechellia, Y = yakuba, E = erecta; [NAME]; P =  pseudoobscura.  The following statistics are all derived from PAML analysis:  6pS: the proportion of sites estimated to belong to the class that has the highest dN/dS in M3; 7dN/dS: for the highest class in M3;8pS: the proportion of sites estimated to belong to the class that has dN/dS > 1 in M2; 9dN/dS: the estimate for the class with the ratio > 1 in M2; 10pS: the proportion of sites estimated to belong to the class that has dN/dS > 1 in M8;11dN/dS: the estimate for the class with the ratio > 1 in M8; *P <.05; **P<.01; ***P<.001.12The genomes in which orthologs were found using the 12 Drosophila genomes. Pr = persimilis, W = willistoni, Mj = mojavensis, V = virilis, and G =grimshawi