Spreadsheet: 1ed601d5-6883-4538-bbf5-3838cf53413d
Sheet: Sheet1

Supplementary Table 15: T. hominis has lost a large number of transport proteins in direct comparison to S. cerevisiae (TransporterDB). This table is split into three sections; i) homologues detected in both organisms, ii)  only homologues in yeast but lost / highly diverged in T. hominis, iii) homologues found in T. hominis but not in yeast. | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4
Number of proteins in S. cerevisiae | Number of proteins in T. hominis | short name | transporter family | transporter family description
proteins conserved in both species
5 | 1 | MIT | 1.A.35 | The CorA Metal Ion Transporter (MIT) Family
3 | 1 | Ctr | 1.A.56 | The Copper Transporter (Ctr) Family
4 | 1 | MIP | 1.A.8 | The Major Intrinsic Protein (MIP) Family
85 | 8 | MFS | 2.A.1 | The Major Facilitator Superfamily (MFS)
1 | 1 | POT | 2.A.17 | The Proton-dependent [NAME] (POT) Family
7 | 2 | AAAP | 2.A.18 | The Amino Acid/Auxin Permease (AAAP) Family
4 | 1 | CaCA | 2.A.19 | The Ca2+:Cation Antiporter ([NAME]) Family
2 | 2 | CPA1 | 2.A.36 | The Monovalent Cation:Proton Antiporter-1 (CPA1) Family
5 | 1 | CDF | 2.A.4 | The Cation Diffusion Facilitator (CDF) Family
3 | 4 | ZIP | 2.A.5 | The Zinc (Zn2+)-Iron (Fe2+) Permease (ZIP) Family
4 | 2 | SulP | 2.A.53 | The Sulfate Permease (SulP) Family
9 | 3 | DMT | 2.A.7 | The Drug/Metabolite Transporter (DMT) Superfamily
24 | 10 | ABC | 3.A.1 | The ATP-binding Cassette (ABC) Superfamily
2 | 4 | F-ATPase | 3.A.2 | The H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) Superfamily
16 | 7 | P-ATPase | 3.A.3 | The P-type ATPase (P-ATPase) Superfamily
1 | 1 | AE | 2.A.31 | The Anion Exchanger (AE) Family
proteins only present in S. cerevisiae
2 | 0 | VIC | 1.A.1 | The Voltage-gated Ion Channel (VIC) Superfamily
3 | 0 | Amt | 1.A.11 | The Ammonia Transporter Channel (Amt) Family
1 | 0 | NSCC2 | 1.A.15 | The Non-selective Cation Channel-2 (NSCC2) Family
1 | 0 | Mid1 | 1.A.16 | The Yeast Stretch-Activated, Cation-Selective, Ca2+ Channel, [NAME] (Mid1) Family
1 | 0 | TRP-CC | 1.A.4 | The Transient Receptor Potential Ca2+ Channel (TRP-CC) Family
1 | 0 | TDT | 2.A.16 | The Telurite-resistance/Dicarboxylate Transporter (TDT) Family
1 | 0 | PiT | 2.A.20 | The Inorganic Phosphate Transporter ([NAME]) Family
1 | 0 | SSS | 2.A.21 | The Solute:Sodium Symporter (SSS) Family
1 | 0 | BASS | 2.A.28 | The Bile Acid:Na+ Symporter (BASS) Family
34 | 0 | MC | 2.A.29 | The Mitochondrial Carrier (MC) Family
24 | 0 | APC | 2.A.3 | The Amino Acid-Polyamine-Organocation (APC) Family
1 | 0 | CCC | 2.A.30 | The Cation-Chloride Cotransporter (CCC) Family
1 | 0 | CPA2 | 2.A.37 | The Monovalent Cation:Proton Antiporter-2 (CPA2) Family
2 | 0 | Trk | 2.A.38 | The K+ Transporter (Trk) Family
10 | 0 | NCS1 | 2.A.39 | The Nucleobase:Cation Symporter-1 (NCS1) Family
1 | 0 | LCT | 2.A.43 | The Lysosomal Cystine Transporter (LCT) Family
1 | 0 | FNT | 2.A.44 | The Formate-Nitrite Transporter (FNT) Family
3 | 0 | DASS | 2.A.47 | The Divalent Anion:Na+ Symporter (DASS) Family
1 | 0 | ClC | 2.A.49 | The Chloride Carrier/Channel (ClC) Family
2 | 0 | GUP | 2.A.50 | The Glycerol Uptake (GUP) Family
1 | 0 | MTC | 2.A.54 | The Mitochondrial Tricarboxylate Carrier (MTC) Family
3 | 0 | Nramp | 2.A.55 | The Metal Ion (Mn2+-iron) [NAME] (Nramp) Family
1 | 0 | ENT | 2.A.57 | The Equilibrative Nucleoside Transporter (ENT) Family
1 | 0 | ACR3 | 2.A.59 | The Arsenical Resistance-3 (ACR3) Family
1 | 0 | RND | 2.A.6 | The Resistance-Nodulation-Cell Division (RND) Superfamily
3 | 0 | MOP | 2.A.66 | The Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily
3 | 0 | OPT | 2.A.67 | The Oligopeptide Transporter (OPT) Family
4 | 0 | AEC | 2.A.69 | The Auxin Efflux Carrier (AEC) Family
2 | 0 | ThrE | 2.A.79 | The Threonine/Serine Exporter (ThrE) Family
1 | 0 | Oxa1 | 2.A.9 | The Cytochrome Oxidase Biogenesis (Oxa1) Family
1 | 0 | ArsAB | 3.A.4 | The Arsenite-Antimonite (ArsAB) Efflux Family
9 | 0 | IISP | 3.A.5 | The Type II (General) Secretory Pathway (IISP) Family
18 | 0 | MPT | 3.A.8 | The Mitochondrial Protein Translocase (MPT) Family
1 | 0 | FeT | 9.A.9 | The Low Affinity Fe2+ Transporter (FeT) Family
present only in T. hominis
0 | 7 | MscS | 1.A.23 | The Small Conductance Mechanosensitive Ion Channel (MscS) Family
0 | 4 | AAA | 2.A.12 | The ATP:ADP Antiporter (AAA) Family
0 | 2 | GMA | 2.A.7.13 | The GDP-Mannose:GMP Antiporter (GMA) Family
0 | 1 | CTL | 2.A.92 | The [NAME]-like (CTL) Family
0 | 1 | MgtE | 9.A.19 | The Mg2+ Transporter-E (MgtE) Family
0 | 1 | Hly III | 9.B.30 | [NAME] (Hly III) Family