Spreadsheet: 2baf2a81-3afa-4f89-b423-fbe0ef779a2d
Sheet: Sheet1

Table S5: Selected Gene ontology for AA-CA comparison | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6
Gene Ontology "gamma-glutamyltransferase activity" (GO:0003840):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
2678 | GGT1 | gamma-glutamyltransferase 1 | 1.57 | 0.00132415 | 22q11.23 | Hs.645535
92086 | GGTLA4 | gamma-glutamyltransferase-like activity 4 | 1.44 | 0.009060544 | 20p11.1 | Hs.355394
728441 | [NAME] | gamma-glutamyltransferase 2 | 1.54 | 0.001874882 | 22q11.21 | [NAME]
Gene Ontology "glutathione transferase activity" (GO:0004364):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
2947 | GSTM3 | glutathione S-transferase M3 | 1.31 | 0.014530713 | 1p13.3 | Hs.2006
2948 | GSTM4 | glutathione S-transferase M4 | 1.42 | 0.024462266 | 1p13.3 | Hs.348387
2946 | GSTM2 | glutathione S-transferase M2 | 1.3 | 0.002089327 | 1p13.3 | Hs.279837
2953 | GSTT2 | glutathione S-transferase theta 2 | 2.82 | 2.2e-09 | 22q11.2;22q11.23 | Hs.654462
2944 | GSTM1 | glutathione S-transferase M1 | 1.27 | 0.021866543 | 1p13.3 | Hs.301961
Gene Ontology "proteolysis" (GO:0006508):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
7345 | UCHL1 | [NAME] esterase L1 | -1.91 | 1.98e-05 | 4p14 | Hs.518731
1075 | CTSC | cathepsin C | -1.31 | 0.048805893 | 11q14.1-q14.3 | Hs.128065
7076 | TIMP1 | TIMP metallopeptidase inhibitor 1 | -1.22 | 0.001882987 | Xp11.3-p11.23 | Hs.522632
165 | AEBP1 | AE binding protein 1 | 1.48 | 0.025192125 | [NAME] | Hs.439463
267 | AMFR | autocrine motility factor receptor | 2.79 | 3.75e-07 | 16q21 | Hs.295137
5698 | PSMB9 | proteasome subunit, beta type, 9 | 1.54 | 0.005308842 | 6p21.3 | Hs.132682
25797 | QPCT | glutaminyl-peptide cyclotransferase | 1.29 | 0.042694833 | 2p22.2 | Hs.79033
51200 | CPA4 | carboxypeptidase A4 | -1.45 | 0.042549564 | 7q32 | Hs.93764
10404 | PGCP | plasma glutamate carboxypeptidase | 1.32 | 0.002887067 | 8q22.2 | Hs.156178
5696 | PSMB8 | proteasome subunit, beta type, 8 | 1.34 | 0.00403762 | 6p21.3 | Hs.180062
8837 | CFLAR | [NAME] and FADD-like apoptosis regulator | -1.41 | 9.09e-05 | 2q33-q34 | Hs.390736
27429 | HTRA2 | HtrA serine peptidase 2 | -1.15 | 0.045179087 | 2p12 | Hs.469045
5329 | PLAUR | plasminogen activator, urokinase receptor | -1.32 | 0.031449885 | 19q13 | Hs.466871
25891 | DKFZP586H2123 | regeneration associated muscle protease | -1.39 | 0.031946152 | 11p13 | Hs.55044
9508 | ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 | -1.33 | 0.049723628 | 4q13.3 | Hs.590919
64167 | LRAP | leukocyte-derived arginine aminopeptidase | 1.97 | 0.016560539 | 5q15 | Hs.591249
Gene Ontology "response to stress" (GO:0006950):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
9588 | PRDX6 | peroxiredoxin 6 | -1.25 | 0.009804809 | 1q25.1 | Hs.573688
2878 | GPX3 | glutathione peroxidase 3 | -1.58 | 0.013543737 | 5q23 | Hs.386793
7345 | UCHL1 | [NAME] esterase L1 | -1.91 | 1.98e-05 | 4p14 | Hs.518731
664 | BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -1.29 | 0.048557707 | 10q26.3 | Hs.144873
183 | AGT | angiotensinogen | -1.54 | 0.015957971 | 1q42-q43 | Hs.19383
7158 | [NAME] | tumor protein p53 binding protein, 1 | -1.15 | 0.006494805 | 15q15-q21 | Hs.440968
9537 | TP53I11 | tumor protein p53 inducible protein 11 | 1.23 | 0.012111495 | 11p11.2 | Hs.554791
4217 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -1.36 | 0.021420306 | 6q22.33 | Hs.186486
5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 | -1.84 | 0.025500906 | 1q25.2-q25.3 | Hs.196384
3569 | IL6 | interleukin 6 | -1.57 | 0.006099513 | 7p21 | Hs.512234
6364 | CCL20 | [NAME] 20 | -1.69 | 0.010573282 | 2q33-q37 | Hs.75498
9734 | HDAC9 | histone deacetylase 9 | -1.41 | 0.035791637 | [NAME] | Hs.196054
7292 | TNFSF4 | tumor necrosis factor superfamily, member 4 | -2.19 | 0.003662519 | 1q25 | [NAME]
861 | [NAME] | runt-related transcription factor 1 | -1.28 | 0.007625352 | 21q22.3 | Hs.149261;Hs.612648
8605 | PLA2G4C | phospholipase A2, group IVC | 1.6 | 0.001558496 | 19q13.3 | Hs.631562
27429 | HTRA2 | HtrA serine peptidase 2 | -1.15 | 0.045179087 | 2p12 | Hs.469045
3306 | HSPA2 | heat shock 70kDa protein 2 | 1.78 | 0.000507916 | 14q24.1 | Hs.432648
5329 | PLAUR | plasminogen activator, urokinase receptor | -1.32 | 0.031449885 | 19q13 | Hs.466871
7422 | VEGFA | vascular endothelial growth factor A | -1.27 | 0.003673845 | 6p12 | Hs.73793
126393 | HSPB6 | heat shock protein, alpha-crystallin-related, [NAME] | 1.5 | 0.019344278 | 19q13.12 | Hs.534538
29923 | HIG2 | hypoxia-inducible protein 2 | -1.19 | 0.036659805 | 7q32.1 | Hs.645397
23583 | SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 1.2 | 0.035193616 | 12q13.11-q13.3 | Hs.632721
53832 | IL20RA | interleukin 20 receptor, alpha | -1.23 | 0.046204288 | 6q22.33-q23.1 | Hs.445868
1839 | HBEGF | heparin-binding EGF-like growth factor | -1.57 | 0.004380097 | 5q23 | Hs.799
6376 | CX3CL1 | [NAME] | 1.48 | 0.049798778 | 16q13 | Hs.531668
Gene Ontology "humoral immune response" (GO:0006959):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
3569 | IL6 | interleukin 6 | -1.57 | 0.006099513 | 7p21 | Hs.512234
6364 | CCL20 | [NAME] 20 | -1.69 | 0.010573282 | 2q33-q37 | Hs.75498
683 | BST1 | bone marrow stromal cell antigen 1 | 1.41 | 0.000719998 | 4p15 | Hs.169998
100 | ADA | adenosine deaminase | 1.55 | 0.02971259 | 20q12-q13.11 | Hs.255479
Gene Ontology "cell adhesion" (GO:0007155):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
3728 | JUP | [NAME] | -1.55 | 0.002436747 | 17q21 | Hs.514174
7052 | TGM2 | transglutaminase 2 | -1.46 | 0.045644679 | 20q12 | Hs.517033
7045 | TGFBI | transforming growth factor, beta-induced, 68kDa | 1.24 | 0.044450866 | 5q31 | Hs.369397
165 | AEBP1 | AE binding protein 1 | 1.48 | 0.025192125 | [NAME] | Hs.439463
183 | AGT | angiotensinogen | -1.54 | 0.015957971 | 1q42-q43 | Hs.19383
9638 | FEZ1 | fasciculation and elongation protein zeta 1 | 1.41 | 0.023194329 | 11q24.2 | Hs.224008
22795 | NID2 | nidogen 2 | -1.41 | 0.000139415 | 14q21-q22 | Hs.369840
3691 | ITGB4 | integrin, beta 4 | -1.25 | 0.01829265 | 17q25 | Hs.632226
8839 | WISP2 | WNT1 inducible signaling pathway protein 2 | 2 | 7.48e-05 | 20q12-q13.1 | Hs.592145
22871 | NLGN1 | neuroligin 1 | 1.73 | 0.00445739 | 3q26.31 | Hs.478289
1009 | CDH11 | cadherin 11, type 2, OB-cadherin | -1.17 | 0.014106746 | 16q22.1 | Hs.116471
80781 | COL18A1 | collagen, type XVIII, alpha 1 | 1.41 | 0.016863257 | 21q22.3 | Hs.517356
10174 | SORBS3 | [NAME] and SH3 domain containing 3 | 1.18 | 0.031262739 | 8p21.3 | Hs.528572
9289 | GPR56 | G protein-coupled receptor 56 | 1.62 | 0.00514293 | 16q12.2-q21 | Hs.513633
1288 | COL4A6 | collagen, type IV, alpha 6 | -1.41 | 0.027256276 | Xq22 | Hs.145586
3655 | ITGA6 | integrin, alpha 6 | -1.64 | 0.005470558 | 2q31.1 | Hs.133397
1829 | [NAME] | desmoglein 2 | -1.79 | 0.015604426 | 18q12.1 | Hs.412597
58494 | [NAME] | junctional adhesion molecule 2 | -1.49 | 0.032296884 | 21q21.2 | Hs.517227
50863 | HNT | neurotrimin | -1.34 | 0.036803162 | 11q25 | Hs.504352
6376 | CX3CL1 | [NAME] | 1.48 | 0.049798778 | 16q13 | Hs.531668
Gene Ontology "transforming growth factor beta receptor signaling pathway" (GO:0007179):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
2331 | FMOD | fibromodulin | -1.51 | 0.022165566 | 1q32 | Hs.519168
Gene Ontology "cell-cell signaling" (GO:0007267):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
1948 | EFNB2 | ephrin-B2 | 2.05 | 0.015305055 | 13q33 | Hs.149239
183 | AGT | angiotensinogen | -1.54 | 0.015957971 | 1q42-q43 | Hs.19383
2050 | EPHB4 | EPH receptor B4 | -1.3 | 0.004495573 | 7q22 | Hs.437008
23475 | [NAME] | quinolinate phosphoribosyltransferase | -1.36 | 0.025003343 | 16p11.2 | Hs.513484
6781 | [NAME] | stanniocalcin 1 | -1.5 | 0.026009284 | 8p21-p11.2 | Hs.25590
3569 | IL6 | interleukin 6 (interferon, beta 2) | -1.57 | 0.006099513 | 7p21 | Hs.512234
3976 | LIF | leukemia inhibitory factor | -1.53 | 0.015011332 | 22q12.2 | Hs.2250
6364 | CCL20 | [NAME] 20 | -1.69 | 0.010573282 | 2q33-q37 | Hs.75498
8839 | WISP2 | WNT1 inducible signaling pathway protein 2 | 2 | 7.48e-05 | 20q12-q13.1 | Hs.592145
22871 | NLGN1 | neuroligin 1 | 1.73 | 0.00445739 | 3q26.31 | Hs.478289
3600 | IL15 | interleukin 15 | 1.38 | 0.034475838 | 4q31 | Hs.168132
2254 | FGF9 | fibroblast growth factor 9 | 1.51 | 0.026820094 | 13q11-q12 | Hs.111
7010 | TEK | TEK tyrosine kinase, endothelial | -2.08 | 0.000584699 | 9p21 | Hs.89640
7292 | TNFSF4 | tumor necrosis factor superfamily, member 4 | -2.19 | 0.003662519 | 1q25 | [NAME]
5744 | PTHLH | parathyroid hormone-like hormone | -1.98 | 0.011791336 | 12p12.1-p11.2 | Hs.591159
9289 | GPR56 | G protein-coupled receptor 56 | 1.62 | 0.00514293 | 16q12.2-q21 | Hs.513633
10252 | SPRY1 | sprouty homolog 1, antagonist of FGF signaling | -1.38 | 0.010499671 | 4q28.1 | Hs.436944
1627 | DBN1 | drebrin 1 | 1.25 | 0.014634767 | 5q35.3 | [NAME]
Gene Ontology "cell proliferation" (GO:0008283):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
678 | ZFP36L2 | zinc finger protein 36, C3H type-like 2 | 1.65 | 0.022706337 | 2p22.3-p21 | Hs.503093;Hs.645068
7345 | UCHL1 | [NAME] esterase L1 | -1.91 | 1.98e-05 | 4p14 | Hs.518731
7045 | TGFBI | transforming growth factor, beta-induced, 68kDa | 1.24 | 0.044450866 | 5q31 | Hs.369397
3638 | INSIG1 | insulin induced gene 1 | 1.23 | 0.016785016 | 7q36 | Hs.520819
7076 | TIMP1 | TIMP metallopeptidase inhibitor 1 | -1.22 | 0.001882987 | Xp11.3-p11.23 | Hs.522632
183 | AGT | angiotensinogen | -1.54 | 0.015957971 | 1q42-q43 | Hs.19383
2050 | EPHB4 | EPH receptor B4 | -1.3 | 0.004495573 | 7q22 | Hs.437008
7077 | TIMP2 | TIMP metallopeptidase inhibitor 2 | 1.18 | 0.017216711 | 17q25 | Hs.633514
9537 | TP53I11 | tumor protein p53 inducible protein 11 | 1.23 | 0.012111495 | 11p11.2 | Hs.554791
4771 | NF2 | neurofibromin 2 | 1.25 | 0.040123896 | 22q12.2 | Hs.187898
3569 | IL6 | interleukin 6 | -1.57 | 0.006099513 | 7p21 | Hs.512234
3976 | LIF | leukemia inhibitory factor | -1.53 | 0.015011332 | 22q12.2 | Hs.2250
3600 | IL15 | interleukin 15 | 1.38 | 0.034475838 | 4q31 | Hs.168132
2254 | FGF9 | fibroblast growth factor 9 | 1.51 | 0.026820094 | 13q11-q12 | Hs.111
7292 | TNFSF4 | tumor necrosis factor superfamily, member 4 | -2.19 | 0.003662519 | 1q25 | [NAME]
80781 | COL18A1 | collagen, type XVIII, alpha 1 | 1.41 | 0.016863257 | 21q22.3 | Hs.517356
8611 | [NAME] | phosphatidic acid phosphatase type 2A | 1.29 | 0.039872021 | 5q11 | Hs.435122
5744 | PTHLH | parathyroid hormone-like hormone | -1.98 | 0.011791336 | 12p12.1-p11.2 | Hs.591159
7422 | VEGFA | vascular endothelial growth factor A | -1.27 | 0.003673845 | 6p12 | Hs.73793
2006 | ELN | [NAME] | 2.2 | 0.002296764 | 7q11.23 | Hs.647061
2321 | FLT1 | fms-related tyrosine kinase 1 | -1.32 | 0.011655628 | 13q12 | Hs.507621
1839 | HBEGF | heparin-binding EGF-like growth factor | -1.57 | 0.004380097 | 5q23 | Hs.799
Gene Ontology "regulation of signal transduction" (GO:0009966):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
5997 | RGS2 | regulator of G-protein signalling 2, 24kDa | -1.3 | 0.013964104 | 1q31 | Hs.78944
183 | AGT | angiotensinogen | -1.54 | 0.015957971 | 1q42-q43 | Hs.19383
7077 | TIMP2 | TIMP metallopeptidase inhibitor 2 | 1.18 | 0.017216711 | 17q25 | Hs.633514
23229 | ARHGEF9 | Cdc42 guanine nucleotide exchange factor (GEF) 9 | 1.28 | 0.00821862 | Xq11.1 | Hs.54697
6000 | RGS7 | regulator of G-protein signalling 7 | -1.73 | 0.021747138 | 1q43;1q23.1 | Hs.130171
2254 | FGF9 | fibroblast growth factor 9 | 1.51 | 0.026820094 | 13q11-q12 | Hs.111
8787 | [NAME] | regulator of G-protein signalling 9 | -1.16 | 0.041110637 | 17q23-q24 | Hs.132327
5900 | RALGDS | ral guanine nucleotide dissociation stimulator | -1.26 | 0.009369154 | 9q34.3 | Hs.106185
8490 | RGS5 | regulator of G-protein signalling 5 | 2.04 | 0.000612139 | 1q23.1 | Hs.24950
10174 | SORBS3 | [NAME] and SH3 domain containing 3 | 1.18 | 0.031262739 | 8p21.3 | Hs.528572
8837 | CFLAR | [NAME] and FADD-like apoptosis regulator | -1.41 | 9.09e-05 | 2q33-q34 | Hs.390736
3486 | IGFBP3 | insulin-like growth factor binding protein 3 | 1.74 | 0.048828594 | 7p13-p12 | Hs.450230
7422 | VEGFA | vascular endothelial growth factor A | -1.27 | 0.003673845 | 6p12 | Hs.73793
10252 | SPRY1 | sprouty homolog 1, antagonist of FGF signaling | -1.38 | 0.010499671 | 4q28.1 | Hs.436944
6654 | SOS1 | son of sevenless homolog 1 | 1.67 | 9.06e-05 | [NAME] | Hs.278733
Gene Ontology "phosphorylation" ([NAME]):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
4638 | MYLK | [NAME], light chain kinase | 1.47 | 0.043535348 | 3q21 | Hs.556600
2050 | EPHB4 | EPH receptor B4 | -1.3 | 0.004495573 | 7q22 | Hs.437008
1969 | EPHA2 | EPH receptor A2 | -1.3 | 0.019267542 | 1p36 | Hs.171596
4217 | MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -1.36 | 0.021420306 | 6q22.33 | Hs.186486
3976 | LIF | leukemia inhibitory factor | -1.53 | 0.015011332 | 22q12.2 | Hs.2250
7010 | TEK | TEK tyrosine kinase, endothelial | -2.08 | 0.000584699 | 9p21 | Hs.89640
8814 | CDKL1 | cyclin-dependent kinase-like 1 | 1.31 | 0.010530446 | 14q22.1 | Hs.280881
5747 | PTK2 | PTK2 protein tyrosine kinase 2 | 1.33 | 0.039265115 | 8q24-qter | Hs.395482
985 | CDC2L2 | cell division cycle 2-like 2 | 1.35 | 0.020839109 | 1p36.33 | Hs.651228
10000 | AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 1.17 | 0.018423445 | 1q43-q44 | Hs.498292
155066 | ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 1.27 | 0.003723735 | 7q36.1 | Hs.556998
4293 | MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | -1.24 | 0.03063814 | 14q24.3-q31 | Hs.445496;Hs.593542
2044 | EPHA5 | EPH receptor A5 | -1.65 | 0.042417213 | 4q13.1 | Hs.479853
57761 | TRIB3 | tribbles homolog 3 | -1.34 | 0.01135507 | 20p13-p12.2 | Hs.516826
54476 | TRIAD3 | TRIAD3 protein | 1.2 | 0.049592333 | 7p22.1 | Hs.487458
2321 | FLT1 | fms-related tyrosine kinase 1 | -1.32 | 0.011655628 | 13q12 | Hs.507621
157 | ADRBK2 | adrenergic, beta, receptor kinase 2 | -1.31 | 0.000828486 | 22q11;22q12.1 | Hs.657494
Gene Ontology "intracellular transport" (GO:0046907):
[NAME] Id | [NAME] | [NAME] | FC | p.value | CL | [NAME] Id
7345 | UCHL1 | [NAME] esterase L1 | -1.91 | 1.98e-05 | 4p14 | Hs.518731
664 | BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -1.29 | 0.048557707 | 10q26.3 | Hs.144873
55186 | SLC25A36 | solute carrier family 25, member 36 | -1.19 | 0.035717817 | 3q23 | Hs.144130
4864 | NPC1 | Niemann-Pick disease, type C1 | -1.26 | 0.03502557 | 18q11-q12 | Hs.464779
22871 | NLGN1 | neuroligin 1 | 1.73 | 0.00445739 | 3q26.31 | Hs.478289
2254 | FGF9 | fibroblast growth factor 9 | 1.51 | 0.026820094 | 13q11-q12 | Hs.111
7351 | UCP2 | uncoupling protein 2 | -1.45 | 0.016124002 | 11q13 | Hs.80658
323 | APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -1.26 | 0.040553784 | 4p14-p13 | Hs.479602
6945 | MLX | MAX-like protein X | -1.16 | 0.005614893 | 17q21.1 | Hs.383019
347733 | TUBB2B | tubulin, beta 2B | -1.14 | 0.03906614 | 6p25 | Hs.300701
81562 | [NAME] | lectin, mannose-binding 2-like | -1.17 | 0.023293985 | 2q11.2 | Hs.158852
FC: fold change; CL: chromosome location.