Spreadsheet: 50480ef7-4ff7-4262-94ab-5b367ed6762b
Sheet: Sheet1

Table S5: Estimated metabolic fluxes of Mycobacterium bovis BCG (BCG) and Mycobacterium tuberculosis (MTB) | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14 | Unnamed: 15
 |  |  |  | µ = 0.01 h-1 (td = 69 h) |  |  |  |  |  |  |  |  | µ = 0.03 h-1 (td = 23 h)
 | BCG (Solution 1) |  |  | BCG (Solution 2) |  |  | MTB (Solution 1) |  |  | MTB (Solution 2) |  |  | BCG
flux | rel | abs | stddev | rel | abs | stddev | rel | abs | stddev | rel | abs | stddev | rel | abs | stddev
 | [%] | [mmol gDW-1 h-1] | [mmol gDW-1 h-1] | [%] | [mmol gDW-1 h-1] | [mmol gDW-1 h-1] | [%] | [mmol gDW-1 h-1] | [mmol gDW-1 h-1] | [%] | [mmol gDW-1 h-1] | [mmol gDW-1 h-1] | [%] | [mmol gDW-1 h-1] | [mmol gDW-1 h-1]
GLYCupt,0 | 0.8362258988720543 | 0.323979 | 0.00651883 | 0.8386447248803528 | 0.33487 | 0.00690088 | 0.8451681430591799 | 0.285655 | 0.00152083 | 0.8452945843108145 | 0.397433 | 0.00152311 | 0.8569250568290214 | 0.530027 | 0.0195815
GLYCupt,U | 0.1637751335725163 | 0.0634514 | 0.0012952 | 0.161355024680753 | 0.0644289 | 0.00165956 | 0.1548318569408201 | 0.052331 | 0.000278543 | 0.1547056283777604 | 0.0727381 | 0.000280258 | 0.1430747814952419 | 0.0884949 | 0.00326911
OLACupt | 0.08077820509511396 | 0.0312959 | 0.00388509 | 0.08074325255009403 | 0.0322407 | 0.00507355 | 0.1479351215730829 | 0.05 | 0.000563267 | 0.1063202536949323 | 0.0499887 | 0.000474436 | 0.4526661945735156 | 0.279984 | 0.0215325
CO2out | 1.342103089590378 | 0.519971 | 0.0145639 | 0.8014044613184605 | 0.32 | 0.0231973 | 0.8580237051238808 | 0.29 | 0.0207838 | 0.6166203360054108 | 0.289917 | 0.0068761 | 0.6631275847908401 | 0.410159 | 0.0218453
SUCCOAout | 0.08663655370002324 | 0.0335656 | 0.00810409 | 0.08077480785075845 | 0.0322533 | 0.0104825 | 0.07730586473995964 | 0.0261283 | 0.00685601 | 0.2851536993987294 | 0.134071 | 0.00256154 | 0 | 0 | 0.0133456
pgi | 0.903843274914178 | 0.350176 | 0¨ | 0.01252179444476445 | 0.00499994 | 0¨ | 0.3473930872876391 | 0.117414 | 0¨ | 0.00725523267066663 | 0.0034112 | 0¨ | 0.2715166154154581 | 0.167939 | 0¨
fbp | 0.3206179180755233 | 0.124217 | 2.19511e-18 | 0.02172527354188215 | 0.00867488 | 3.17654e-18 | 0.1416185877521554 | 0.0478651 | 2.90118e-19 | 0.02594205087085337 | 0.0121972 | 1.06385e-19 | 0.1383105208868884 | 0.0855481 | 3.78464e-18
fba | 0.3206179180755233 | 0.124217 | 2.19511e-18 | 0.02172527354188215 | 0.00867488 | 3.17654e-18 | 0.1416185877521554 | 0.0478651 | 2.90118e-19 | 0.02594205087085337 | 0.0121972 | 1.06385e-19 | 0.1383105208868884 | 0.0855481 | 3.78464e-18
gapA | 0.6439718142632217 | 0.249494 | 0.00770822 | 0.9457925013586309 | 0.377654 | 0.00782926 | 0.8159835022752422 | 0.275791 | 0.00179874 | 0.9243466738697198 | 0.434601 | 0.0018009 | 0.7641070164036202 | 0.472617 | 0.0228505
eno | 0.6168520765041428 | 0.238987 | 0.00770822 | 0.9213997530672504 | 0.367914 | 0.00782926 | 0.7685584610013432 | 0.259762 | 0.00179874 | 0.882936208315698 | 0.415131 | 0.0018009 | 0.707535059383498 | 0.437626 | 0.0228505
pyk | 0.4999716077743076 | 0.193704 | 0.00776726 | 0.7926766658569142 | 0.316515 | 0.0106931 | 0.6191291947003722 | 0.209257 | 0.00184636 | 0.72299439990982 | 0.339931 | 0.00204037 | 0.6624760315720378 | 0.409756 | 0.0226604
gnd | 0.8994528043775649 | 0.348475 | 2.23993e-18 | 0.008407358896466056 | 0.00335705 | 3.45223e-18 | 0.3386974608415733 | 0.114475 | 1.72566e-18 | 0.0004533031599141589 | 0.00021313 | 6.50443e-19 | 0.2616721798092873 | 0.16185 | 1.09525e-17
tkt1 | -0.2893529153653563 | -0.112104 | 1.76149e-18 | 0.006714767630272052 | 0.0026812 | 2.79274e-18 | -0.1011331830312498 | -0.0341816 | 7.60431e-19 | 0.0112762165254769 | 0.00530175 | 2.42498e-19 | -0.06054821008791927 | -0.0374504 | 2.75064e-18
tkt2 | -0.2953772294349947 | -0.114438 | 8.67526e-19 | 0.001048940768697142 | 0.000418841 | 1.28028e-18 | -0.1046413165042339 | -0.0353673 | 2.09813e-19 | 0.004989206054818353 | 0.00234578 | 1.90953e-19 | -0.07597498553002156 | -0.0469922 | 4.20973e-18
tal | -0.295377229434995 | -0.114438 | 5.36486e-19 | 0.00104894076869714 | -0.000418841 | 8.28149e-19 | -0.1046413165042339 | -0.0353673 | 7.0638e-19 | 0.00498920605481835 | 0.00234578 | 3.55715e-19 | -0.0759749855300216 | -0.0469922 | 1.07852e-18
pdh | 0.4873344862297705 | 0.188808 | 0.00885472 | 0.8192332061938546 | 0.327119 | 0.0133393 | 0.5694318699591107 | 0.19246 | 0.00176509 | 0.6084169376673593 | 0.28606 | 0.00175165 | 0.4538092420318113 | 0.280691 | 0.021873
cs | 0.09413081072709908 | 0.0364691 | 0.00484486 | 0.1001402457807307 | 0.0399859 | 0.00675323 | 0.07987046800755061 | 0.0269951 | 0.00515645 | 0.2911174870419486 | 0.136875 | 0.00200364 | 0.05897801533332687 | 0.0364792 | 0.00530702
icdh | 0.006501639005755878 | 0.00251893 | 0.00182281 | 0.00971402382675639 | 0.0038788 | 0.0019484 | 0.04557141420058819 | 0.0154025 | 0.0113567 | 0.0719376567248937 | 0.033823 | 0.00274564 | 0.004108503820397657 | 0.0025412 | 0.00456478
kor/kgd | -0.0009926541568799525 | -0.000384584 | 0.000499086 | -0.001895732270804585 | -0.000756964 | 0.000499753 | 0.04300681093299723 | 0.0145357 | 0.0112731 | 0.06613253475863037 | 0.0310936 | 0.00354254 | -0.05449668726415551 | -0.0337074 | 0.00600599
scs, gabD1/D2 | -0.08762920785690319 | -0.033950184 | 0.008119443426953352 | -0.08267054012156304 | -0.033010264 | 0.0104944060961547 | -0.03429905380696241 | -0.0115926 | 0.01319422815969543 | -0.219021164640099 | -0.1029774 | 0.004371621761223173 | -0.05450615396057051 | -0.03371325536 | 0.01463478579413105
sdh | 0 | 0 | 0.00847633 | 0.007755616718298819 | 0.00309681 | 0.012804 | 0 | 0 | 0.0109279 | 0.0001597189107792697 | 0 | 0.000875535 | 0.0003633419668176718 | 0.000224735 | 0.00856486
fuma/b | 0 | 0 | 0.00847633 | 0.007755616718298819 | 0.00309681 | 0.012804 | 0 | 0 | 0.0109279 | 0.0001597189107792697 | 0 | 0.000875535 | 0.0003633419668176718 | 0.000224735 | 0.00856486
[NAME] | 0.087629249154686 | 0.0339502 | 0.00493865 | 0.09042622195397435 | 0.0361071 | 0.00684323 | 0.03429905380696242 | 0.0115926 | 0.00635322 | 0.2191798303170549 | 0.103052 | 0.00137022 | 0.05486951151292921 | 0.033938 | 0.00767743
ms | 0.087629249154686 | 0.0339502 | 0.00493865 | 0.09042622195397435 | 0.0361071 | 0.00684323 | 0.03429905380696242 | 0.0115926 | 0.00635322 | 0.2191798303170549 | 0.103052 | 0.00137022 | 0.05486951151292921 | 0.033938 | 0.00767743
pck | 0.1035985855509382 | 0.0401372 | 0¨ | 0.1164077545899188 | 0.0464815 | 0¨ | 0.1312039551934104 | 0.0443451 | 0¨ | 0.1431479185232607 | 0.067304 | 0¨ | 0.01196846676431881 | 0.00740276 | 0¨
mez/pca | -0.0495991533954521 | -0.0192162 | 0.00796458 | -0.0786751281621041 | -0.0314149 | 0.012478 | 0.0113451148864154 | 0.00383449 | 0.00129854 | 0.000379455559785695 | -0.000178409 | 0.000921668 | 0.0346962597935078 | 0.0214604 | 0.00389031
* Fluxes pgi and pck cannot be determined from the labelling data and therefore both fluxes (amongst some reversibility rates of EMP and PPP) are set to their fitted values for the statistical calculations.