Spreadsheet: 7dcc5e90-50b5-4ee3-a55c-e5ac2665ac59
Sheet: Top 10% of Decay & Expression

Gene Ontology Categories for genes with a discordant relationship between decay and gene expression across individuals
GO Subcategory | Expected | Observed | [NAME] | Enrichment
nucleus | 264.916 | 377 | 9.07282e-14 | up
macromolecule biosynthetic process | 182.384 | 271 | 1.31708e-10 | up
cellular macromolecule biosynthetic process | 178.7 | 266 | 1.36135e-10 | up
DNA binding | 117.626 | 187 | 2.69563e-09 | up
regulation of biosynthetic process | 156.92 | 234 | 2.69563e-09 | up
regulation of cellular biosynthetic process | 155.886 | 233 | 2.69563e-09 | up
cellular biosynthetic process | 219.288 | 305 | 2.69563e-09 | up
nucleic acid metabolic process | 190.721 | 273 | 2.69563e-09 | up
transcription | 140.375 | 214 | 2.93157e-09 | up
regulation of cellular metabolic process | 192.983 | 274 | 4.12423e-09 | up
cellular macromolecule metabolic process | 292.06 | 382 | 4.22789e-09 | up
intracellular part | 557.041 | 644 | 4.29992e-09 | up
regulation of cellular process | 322.759 | 414 | 4.29992e-09 | up
biosynthetic process | 225.04 | 309 | 4.38427e-09 | up
regulation of transcription | 135.528 | 206 | 6.45857e-09 | up
nucleic acid binding | 161.574 | 236 | 7.95953e-09 | up
regulation of metabolic process | 202.678 | 282 | 1.07336e-08 | up
regulation of macromolecule biosynthetic process | 148.583 | 220 | 1.15903e-08 | up
membrane-bounded organelle | 430.626 | 520 | 1.34473e-08 | up
intracellular | 573.457 | 656 | 1.34482e-08 | up
intracellular membrane-bounded organelle | 430.173 | 519 | 1.56407e-08 | up
gene expression | 192.143 | 268 | 2.48776e-08 | up
transcription regulator activity | 79.3649 | 134 | 2.78697e-08 | up
regulation of nitrogen compound metabolic process | 156.468 | 227 | 2.78697e-08 | up
regulation of biological process | 338.529 | 424 | 3.83386e-08 | up
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 219.417 | 297 | 3.99688e-08 | up
RNA metabolic process | 132.943 | 198 | 5.47026e-08 | up
regulation of primary metabolic process | 183.289 | 256 | 5.47026e-08 | up
transcription, DNA-dependent | 99.7232 | 158 | 5.64296e-08 | up
RNA biosynthetic process | 99.9171 | 158 | 6.28606e-08 | up
macromolecule metabolic process | 319.528 | 402 | 8.41086e-08 | up
organelle | 475.931 | 559 | 8.57079e-08 | up
regulation of macromolecule metabolic process | 175.598 | 246 | 8.64918e-08 | up
regulation of transcription, DNA-dependent | 92.6139 | 148 | 1.02176e-07 | up
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 155.175 | 222 | 1.15906e-07 | up
regulation of RNA metabolic process | 95.393 | 151 | 1.24159e-07 | up
intracellular organelle | 475.22 | 557 | 1.30771e-07 | up
cellular metabolic process | 378.793 | 461 | 1.50299e-07 | up
regulation of gene expression | 151.879 | 217 | 1.86262e-07 | up
cellular nitrogen compound metabolic process | 234.282 | 309 | 1.86262e-07 | up
nitrogen compound metabolic process | 240.357 | 315 | 2.30941e-07 | up
biological regulation | 357.465 | 435 | 7.83302e-07 | up
transcription factor activity | 50.0878 | 87 | 7.19706e-06 | up
sensory perception | 36.1925 | 11 | 1.08592e-05 | down
[NAME] process | 387.453 | 457 | 1.75962e-05 | up
binding | 622.446 | 683 | 2.1441e-05 | up
fever | 0.710923 | 7 | 3.55121e-05 | up
metabolic process | 424.551 | 492 | 3.55121e-05 | up
cellular process | 591.101 | 652 | 4.54595e-05 | up
transporter activity | 58.0372 | 28 | 8.21615e-05 | down
transcription activator activity | 23.3312 | 47 | 8.83435e-05 | up
regulation of fever | 0.581665 | 6 | 0.000133696 | up
positive regulation of fever | 0.581665 | 6 | 0.000133696 | up
heat generation | 0.840182 | 7 | 0.000144327 | up
negative regulation of transcription, DNA-dependent | 22.6849 | 45 | 0.000198715 | up
temperature homeostasis | 1.55111 | 9 | 0.000253837 | up
negative regulation of RNA metabolic process | 22.9434 | 45 | 0.000257506 | up
regulation of heat generation | 0.646294 | 6 | 0.000283783 | up
positive regulation of heat generation | 0.646294 | 6 | 0.000283783 | up
neurological system process | 59.5237 | 31 | 0.000297059 | down
nuclear lumen | 79.5588 | 116 | 0.000373432 | up
positive regulation of biosynthetic process | 40.6519 | 68 | 0.000396714 | up
positive regulation of cellular biosynthetic process | 40.0702 | 67 | 0.000456495 | up
vasculature development | 18.0316 | 37 | 0.000515591 | up
[NAME] and ERK2 cascade | 2.52055 | 11 | 0.00051878 | up
positive regulation of biological process | 120.081 | 162 | 0.000524858 | up
negative regulation of metabolic process | 46.9856 | 75 | 0.000685084 | up
negative regulation of cellular metabolic process | 43.0432 | 70 | 0.00068636 | up
intrinsic to membrane | 258.388 | 207 | 0.000691287 | down
cognition | 41.4921 | 19 | 0.000717669 | down
positive regulation of macromolecule biosynthetic process | 37.8728 | 63 | 0.000837678 | up
[NAME] transporter activity | 45.3052 | 22 | 0.000848152 | down
signaling pathway | 134.946 | 177 | 0.000929122 | up
positive regulation of inflammatory response | 2.26203 | 10 | 0.000945658 | up
immune system process | 54.935 | 84 | 0.000961075 | up
organ development | 102.373 | 140 | 0.000961075 | up
nuclear part | 100.757 | 138 | 0.000997863 | up