Spreadsheet: d722daa3-9d84-4700-ad07-aea29959e53d
Sheet: Sheet1

Test Referenced | Entry Type | Mayo ID | Description | Reporting Description | Method | Collection Container | Temperature | Stability | [NAME] | Unit of Measure | [NAME] | Minimum Volume | Reject Due To | Reference Values | Days/Times Performed | Analytic Time | Maximum Lab Time | CPT Units | CPT Code | LOINC® Code | LOINC® Attributes | Always Performed | Orderable Separately | Performing Location
ESTF | Test | ESTF | Estrogens, Estrone (E1) and [NAME] (E2), Fractionated, Serum | Estrogens, E1+E2, fractionated, S | Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) | Plain, Red-Top Tube: Red OR Serum Gel Tube: SGT OR |  |  | 1.2 | mL | Container/Tube:  Preferred: Red top  Acceptable: Serum gel  [NAME]: 1.2 mL Collection Instructions: Serum must be separated from gel within 24 hours of draw. | 0.8 mL | Hemolysis	Mild OK; Gross OK Thawing	Warm OK; Cold OK Lipemia	Mild OK; [NAME] OK Icterus	Mild OK; [NAME] OK Other	NA | ESTRONE (E1) CHILDREN* 1-14 days: Estrone levels in newborns are very elevated at birth but will fall to prepubertal levels within a few days. [NAME] Stages#	Mean Age	Reference Range Stage I (>14 days and prepubertal)	7.1 years	Undetectable-16 pg/mL Stage II	11.5 years	Undetectable-22 pg/mL Stage III	13.6 years	10-25 pg/mL Stage IV	15.1 years	10-46 pg/mL Stage V	18 years	10-60 pg/mL #[NAME] onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (+/- 2) years. For boys there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18. Females Tanner Stages#	Mean Age	Reference Range Stage I (>14 days and prepubertal)	7.1 years	Undetectable-29 pg/mL Stage II	10.5 years	10-33 pg/mL Stage III	11.6 years	15-43 pg/mL Stage IV	12.3 years	16-77 pg/mL Stage V	14.5 years	17-200 pg/mL #[NAME] onset (transition from Tanner stage I to Tanner stage II) occurs for girls at a median age of 10.5 (+/- 2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18. *The reference ranges for children are based on the published literature(1,2), cross-correlation of our assay with assays used to generate the literature data and on our data for young adults. ADULTS Males: 10-60 pg/mL Females Premenopausal: 17-200 pg/mL Postmenopausal: 7-40 pg/mL Conversion factor E1: pg/mL x 3.704=pmol/L (molecular weight=270)   [NAME] (E2) CHILDREN* 1-14 days: [NAME] levels in newborns are very elevated at birth but will fall to prepubertal levels within a few days. [NAME] Stages#	Mean Age	Reference Range Stage I (>14 days and prepubertal)	7.1 years	Undetectable-13 pg/mL Stage II	12.1 years	Undetectable-16 pg/mL Stage III	13.6 years	Undetectable-26 pg/mL Stage IV	15.1 years	Undetectable-38 pg/mL Stage V	18 years	10-40 pg/mL #[NAME] onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (+/- 2) years. For boys there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18. Females Tanner Stages#	Mean Age	Reference Range Stage I (>14 days and prepubertal)	7.1 years	Undetectable-20 pg/mL Stage II	10.5 years	Undetectable-24 pg/mL Stage III	11.6 years	Undetectable-60 pg/mL Stage IV	12.3 years	15-85 pg/mL Stage V	14.5 years	15-350 pg/mL** #[NAME] onset (transition from Tanner stage I to Tanner stage II) occurs for girls at a median age of 10.5 (+/- 2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18. *The reference ranges for children are based on the published literature(1,2), cross-correlation of our assay with assays used to generate the literature data and on our data for young adults. ADULTS Males: 10-40 pg/mL Females Premenopausal: 15-350 pg/mL** Postmenopausal: <10 pg/mL **E2 levels vary widely through the menstrual cycle. Conversion factor E2: pg/mL x 3.676=pmol/L (molecular weight=272) | Monday through Saturday; 1 p.m. | 2 days | 4 days |  | Profile |  |  |  |  | Rochester
ESTF | [NAME] | SERUM | Serum |  |  |  | Refrigerated | 7 days
ESTF | Component | E1 | Estrone, Serum | Estrone, S | Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) | Serum Gel Tube: SGT |  |  | 1.2 | mL | Container/Tube: Preferred: Red top  Acceptable: Serum gel  [NAME]: 1.2 mL Collection Instructions: Serum must be separated from gel within 24 hours of draw. Additional Information: See Steroid Pathways in Special Instructions. | 0.8 mL | Hemolysis	Mild OK; Gross OK Thawing	Warm OK; Cold OK Lipemia	Mild OK; [NAME] OK Icterus	Mild OK; [NAME] OK Other	NA | CHILDREN* 1-14 days: Estrone levels in newborns are very elevated at birth but will fall to prepubertal levels within a few days. [NAME] Stages#	Mean Age	Reference Range Stage I (>14 days and prepubertal)	7.1 years	Undetectable-16 pg/mL Stage II	11.5 years	Undetectable-22 pg/mL Stage III	13.6 years	10-25 pg/mL Stage IV	15.1 years	10-46 pg/mL Stage V	18 years	10-60 pg/mL #[NAME] onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (+/- 2) years. For boys there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.   Females Tanner Stages#	Mean Age	Reference Range Stage I (>14 days and prepubertal)	7.1 years	Undetectable-29 pg/mL Stage II	10.5 years	10-33 pg/mL Stage III	11.6 years	15-43 pg/mL Stage IV	12.3 years	16-77 pg/mL Stage V	14.5 years	17-200 pg/mL #[NAME] onset (transition from Tanner stage I to Tanner stage II) occurs for girls at a median age of 10.5 (+/- 2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.  *The reference ranges for children are based on the published literature(1,2), cross-correlation of our assay with assays used to generate the literature data and on our data for young adults.   ADULTS Males: 10-60 pg/mL Females Premenopausal: 17-200 pg/mL Postmenopausal: 7-40 pg/mL Conversion factor E1: pg/mL x 3.704=pmol/L (molecular weight=270) | Monday through Saturday; 1 p.m. | 2 days | 4 days | 1 | 82679 |  |  | Yes | Yes
E1 | [NAME] | SERUM | Serum |  |  |  | Refrigerated | 7 days
E1 | Result | 81418 | Estrone, S | Estrone, S | Numeric |  |  |  |  | pg/mL |  |  |  |  |  |  |  |  |  | 2258-2 | Estrone:MCnc:Pt:Ser/Plas:Qn:
ESTF | Component | EEST | [NAME], Serum | Estradiol, S | Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) | Serum Gel Tube: SGT |  |  | 1.2 | mL | Container/Tube:  Preferred: Red top  Acceptable: Serum gel [NAME]: 1.2 mL Collection Instructions: Serum must be separated from gel within 24 hours of draw. | 0.8 mL | Hemolysis	Mild OK; Gross OK Thawing	Warm OK; Cold OK Lipemia	Mild OK; [NAME] OK Icterus	Mild OK; [NAME] OK Other	NA | CHILDREN* 1-14 days: [NAME] levels in newborns are very elevated at birth but will fall to prepubertal levels within a few days. [NAME] Stages#	Mean Age	Reference Range Stage I (>14 days and prepubertal)	7.1 years	Undetectable-13 pg/mL Stage II	12.1 years	Undetectable-16 pg/mL Stage III	13.6 years	Undetectable-26 pg/mL Stage IV	15.1 years	Undetectable-38 pg/mL Stage V	18 years	10-40 pg/mL #[NAME] onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (+/- 2) years. For boys, there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.   Females Tanner Stages#	Mean Age	Reference Range Stage I (>14 days and prepubertal)	7.1 years	Undetectable-20 pg/mL Stage II	10.5 years	Undetectable-24 pg/mL Stage III	11.6 years	Undetectable-60 pg/mL Stage IV	12.3 years	15-85 pg/mL Stage V	14.5 years	15-350 pg/mL** #[NAME] onset (transition from Tanner stage I to Tanner stage II) occurs for girls at a median age of 10.5 (+/- 2) years. There is evidence that it may occur up to 1 year earlier in obese girls and in African American girls. Progression through Tanner stages is variable. Tanner stage V (adult) should be reached by age 18.   *The reference ranges for children are based on the published literature(1,2), cross-correlation of our assay with assays used to generate the literature data, and on our data for young adults.   ADULTS Males: 10-40 pg/mL Females	 Premenopausal: 15-350 pg/mL** Postmenopausal: <10 pg/mL **E2 levels vary widely through the menstrual cycle. Conversion factor E2: pg/mL x 3.676=pmol/L (molecular weight=272) | Monday through Friday; 1 p.m. | 2 days | 4 days | 1 | 82670 |  |  | Yes | Yes
EEST | [NAME] | SERUM | Serum |  |  |  | Refrigerated | 7 days
EEST | Result | 81816 | Estradiol, S | Estradiol, S | Numeric |  |  |  |  | pg/mL |  |  |  |  |  |  |  |  |  | 2243-4 | [NAME]:MCnc:Pt:Ser/Plas:Qn: