Spreadsheet: 41bb505d-76a8-42ba-b2de-df28f5229b11
Sheet: Sheet1

Representative Public ID | [NAME] | [NAME] | Coincidence Cluster . | p value | Change | Fold change | Probe Set ID | OMIM | Ensembl | UniGene ID | [NAME] | [NAME] | Unnamed: 13 | GO Biological Process Description | GO Molecular Function Description | GO Cellular Component Description | [NAME] | [NAME]
Y09305 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | DYRK4 | 10_1 | 0.027050877 | decreased | 2.23041816242718 | 101_at | 609181 | ENSG00000010219 | 439530 | 8798 | NM_003845 |  | protein amino acid phosphorylation | protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity | --- | --- | ---
U54778 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | [NAME] | 2_4 | 0.035267371 | decreased | 1.745524751877893 | 1011_s_at | 247200 /// 605066 | ENSG00000108953 | 513851 | 7531 | NM_006761 |  | --- | protein domain specific binding | --- | --- | ---
Z21966 | POU domain, class 6, transcription factor 1 | POU6F1 | 5_10 | 0.021980614 | increased | 1.683762740699438 | 104_at | --- | ENSG00000184271 | 552576 | 5463 | NM_002702 |  | regulation of transcription, DNA-dependent /// brain development /// heart development /// muscle development | transcription factor activity | nucleus | --- | ---
M81601 | transcription elongation factor A (SII), 1 | TCEA1 | 9_1 | 0.029932299 | decreased | 1.717626274241063 | 1073_at | 601425 | ENSG00000187735 | 491745 | 6917 | NM_006756 /// NM_201437 |  | transcription /// RNA elongation /// regulation of transcription from RNA polymerase II promoter | transcription factor activity /// general [NAME] polymerase II transcription factor activity | nucleus | --- | ---
X07024 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | TAF1 | 5_10 | 0.042574012 | increased | 2.128037341094971 | 112_g_at | 313650 | ENSG00000147133 | 158560 | 6872 | NM_004606 /// NM_138923 |  | G1 phase of mitotic cell cycle /// transcription /// transcription initiation /// regulation of transcription, DNA-dependent /// cell cycle /// autophosphorylation | DNA binding /// histone acetyltransferase activity /// protein serine/threonine kinase activity /// protein binding /// ATP binding /// transferase activity | nucleus /// transcription factor TFIID complex | --- | ---
HG620-HT620 | --- | --- | 5_10 | 0.01583482 | increased | 1.231254422878489 | 1150_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
HG1471-HT3923 | --- | --- | 2_5 | 0.036857875 | decreased | 1.774476970492857 | 1171_s_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
HG1827-HT1856 | --- | --- | 1_10 | 0.009623961 | increased | 1.408755167329245 | 1175_s_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
X07109 | protein kinase C, beta 1 | PRKCB1 | 1_10 | 0.007699042 | increased | 1.353722341734736 | 1217_g_at | 176970 | ENSG00000166501 | 460355 | 5579 | NM_002738 /// NM_212535 |  | protein amino acid phosphorylation /// intracellular signaling cascade | protein kinase C activity /// calcium ion binding /// ATP binding /// transferase activity /// diacylglycerol binding | cytoplasm /// plasma membrane | G_Protein_Signaling /// Wnt_signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction /// Phosphatidylinositol signaling system | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP04070+2.7.1.37
L22005 | cell division cycle 34 | CDC34 | 4_3 | 0.03527816 | decreased | 1.837746415250089 | 1274_s_at | 116948 | ENSG00000099804 | 514997 | 997 | NM_004359 |  | G1/S transition of mitotic cell cycle /// DNA replication initiation /// ubiquitin cycle | ubiquitin conjugating enzyme activity /// ubiquitin-protein ligase activity /// ligase activity | nucleus | Ubiquitin mediated proteolysis | www.genome.ad.jp/dbget-bin/show_pathway?MAP04120+6.3.2.19
HG2709-HT2805 | --- | --- | 4_3 | 0.002594318 | decreased | 1.628146338553156 | 1285_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
L02321 | glutathione S-transferase M5 | GSTM5 | 3_2 | 0.008294841 | decreased | 1.912380467024727 | 1290_g_at | 138385 | ENSG00000134201 | 75652 | 2949 | NM_000851 |  | metabolism | glutathione transferase activity /// glutathione transferase activity /// transferase activity | --- | Glutathione metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00480+2.5.1.18
D84110 | RNA binding protein with multiple splicing | RBPMS | 10_1 | 0.046787145 | decreased | 1.815360136801982 | 1297_at | 601558 | ENSG00000157110 | 334587 | 11030 | NM_001008710 /// NM_001008711 /// NM_001008712 /// NM_006867 |  | RNA processing | nucleotide binding /// RNA binding | --- | --- | ---
D26599 | proteasome (prosome, macropain) subunit, beta type, 2 | PSMB2 | 9_1 | 0.049522789 | decreased | 2.146798727506311 | 1310_at | 602175 | ENSG00000126067 | 471441 | 5690 | NM_002794 |  | ubiquitin-dependent protein catabolism | threonine endopeptidase activity | proteasome core complex (sensu [NAME]) | Proteasome_Degradation /// Proteasome | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03050+3.4.25.1
[NAME] | TNF receptor-associated factor 5 | TRAF5 | 5_9 | 0.037225386 | increased | 0.9530278248697586 | 1328_at | 602356 | ENSG00000082512 | 523930 | 7188 | NM_004619 /// NM_145759 |  | apoptosis /// signal transduction /// protein ubiquitination /// positive regulation of I-kappaB kinase/NF-kappaB cascade | ubiquitin-protein ligase activity /// signal transducer activity /// zinc ion binding | ubiquitin ligase complex | --- | ---
U74382 | telomeric repeat binding factor (NIMA-interacting) 1 | TERF1 | 6_1 | 0.024567331 | decreased | 1.348825192026251 | 1329_s_at | 600951 | ENSG00000147601 | 442707 | 7013 | NM_003218 /// NM_017489 |  | cytokinesis /// telomerase-dependent telomere maintenance /// cell cycle /// regulation of mitosis /// regulation of transcription | protein binding /// telomeric DNA binding | chromosome, telomeric region /// nucleus | --- | ---
U40705 | telomeric repeat binding factor (NIMA-interacting) 1 | TERF1 | 5_9 | 0.019845049 | increased | 1.679404615208066 | 1342_g_at | 600951 | ENSG00000147601 | 442707 | 7013 | NM_003218 /// NM_017489 |  | cytokinesis /// telomerase-dependent telomere maintenance /// cell cycle /// regulation of mitosis /// regulation of transcription | protein binding /// telomeric DNA binding | chromosome, telomeric region /// nucleus | --- | ---
L04751 | cytochrome P450, family 4, subfamily A, polypeptide 11 | CYP4A11 | 10_1 | 0.021417906 | decreased | 1.606557475815364 | 1391_s_at | 601310 | ENSG00000187048 | 1645 | 1579 | NM_000778 |  | electron transport /// fatty acid metabolism /// transport | fatty acid (omega-1)-hydroxylase activity /// alkane 1-monooxygenase activity | endoplasmic reticulum /// microsome /// membrane | Fatty acid metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00071+1.14.15.3
L32976 | mitogen-activated protein kinase kinase kinase 11 | MAP3K11 | 10_1 | 0.038628865 | decreased | 1.892681173873376 | 1397_at | 600050 | ENSG00000173327 | 502872 | 4296 | NM_002419 |  | G1 phase of mitotic cell cycle /// microtubule-based process /// activation of JNK /// cell proliferation /// autophosphorylation /// protein oligomerization | protein serine/threonine kinase activity /// JUN kinase kinase kinase activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity /// protein homodimerization activity | centrosome /// microtubule | --- | ---
M21121 | chemokine (C-C motif) ligand 5 | [NAME] | 4_1 | 0.00639234 | decreased | 1.80593000087241 | 1405_i_at | 187011 | ENSG00000161570 | 514821 | 6352 | NM_002985 |  | calcium ion homeostasis /// exocytosis /// cell motility /// chemotaxis /// inflammatory response /// cellular defense response /// response to oxidative stress /// cell adhesion /// signal transduction /// cell-cell signaling /// sensory perception /// response to virus | chemokine activity | extracellular region | --- | ---
D30742 | calcium/calmodulin-dependent protein kinase IV | CAMK4 | 4_1 | 0.01568267 | decreased | 1.300800725688892 | 1421_at | 114080 | ENSG00000152495 | 220629 | 814 | NM_001744 |  | protein amino acid phosphorylation /// signal transduction | protein serine/threonine kinase activity /// calcium- and calmodulin-dependent protein kinase activity /// calmodulin binding /// ATP binding /// transferase activity | nucleus | Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
D88795 | protocadherin beta 11 | PCDHB11 | 10_1 | 0.051761675 | decreased | 1.089180347386237 | 1425_at | 606337 | ENSG00000197479 | 283084 | 56125 | /// NM_018931 |  | cell adhesion /// homophilic cell adhesion /// synaptic transmission /// synaptogenesis /// calcium-dependent cell-cell adhesion | calcium ion binding /// protein binding | integral to plasma membrane /// membrane | --- | ---
D00763 | proteasome (prosome, macropain) subunit, alpha type, 4 | PSMA4 | 7_1 | 0.025155012 | decreased | 1.119597556828916 | 1449_at | --- | ENSG00000041357 | 251531 | 5685 | NM_002789 |  | ubiquitin-dependent protein catabolism | threonine endopeptidase activity | proteasome core complex (sensu [NAME]) | Circadian_Exercise /// Proteasome_Degradation /// Proteasome | [NAME] /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Proteasome_Degradation/Hs_Proteasome_Degradation.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03050+3.4.25.1
U12535 | epidermal growth factor receptor pathway substrate 8 | EPS8 | 8_3 | 0.026819504 | decreased | 1.707701707747084 | 1467_at | 600206 | ENSG00000151491 | 26139 | 2059 | NM_004447 |  | signal transduction /// epidermal growth factor receptor signaling pathway /// cell proliferation | SH3/SH2 adaptor activity | --- | --- | ---
U82130 | tumor susceptibility gene 101 | TSG101 | 10_1 | 0.049117728 | decreased | 2.159009869245861 | 147_at | 601387 | ENSG00000074319 | 523512 | 7251 | NM_006292 |  | regulation of cell growth /// ubiquitin cycle /// protein transport | DNA binding /// transcription corepressor activity | membrane | --- | ---
M34668 | protein tyrosine phosphatase, receptor type, A | PTPRA | 4_1 | 0.02731241 | decreased | 2.274944475906815 | 1496_at | 176884 | ENSG00000132670 | --- | 5786 | NM_002836 /// NM_080840 /// NM_080841 |  | protein amino acid dephosphorylation | [NAME] receptor protein tyrosine phosphatase activity /// hydrolase activity | integral to plasma membrane | --- | ---
[NAME] | G protein-coupled receptor 19 | GPR19 | 5_10 | 0.020063694 | increased | 1.427855759579568 | 156_s_at | 602927 | ENSG00000183150 | 92458 | 2842 | NM_006143 |  | signal transduction /// G-protein coupled receptor protein signaling pathway | rhodopsin-like receptor activity /// receptor activity | integral to plasma membrane | --- | ---
L27559 | insulin-like growth factor binding protein 5 | IGFBP5 | 10_1 | 0.049169907 | decreased | 2.076855782108301 | 1601_s_at | 146734 | ENSG00000115461 | 369982 | 3488 | NM_000599 |  | regulation of cell growth /// signal transduction | insulin-like growth factor binding | extracellular region | --- | ---
HG2036-HT2090 | --- | --- | 10_1 | 0.040127163 | decreased | 1.32494870747805 | 1624_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
L23959 | transcription factor Dp-1 | TFDP1 | 10_1 | 0.034689329 | decreased | 1.618120173335011 | 1670_at | 189902 | ENSG00000198176 | 79353 | 7027 | NM_007111 |  | regulation of cell cycle /// transcription /// regulation of transcription from RNA polymerase II promoter /// cell proliferation | transcription factor activity /// transcription coactivator activity | nucleus /// transcription factor complex | Cell_cycle_KEGG /// G1_to_S_cell_cycle_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Cell_cycle_KEGG/Hs_Cell_cycle_KEGG.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G1_to_S_cell_cycle_Reactome/Hs_G1_to_S_cell_cycle_Reactome.htm
X82554 | S-phase response (cyclin-related) | SPHAR | 7_4 | 0.021960497 | decreased | 2.644707911964968 | 1685_at | --- | ENSG00000168118 | 511754 | 10638 | NM_006542 |  | regulation of cell cycle /// DNA replication | --- | --- | --- | ---
U07620 | mitogen-activated protein kinase 10 | MAPK10 | 6_1 | 0.047443936 | decreased | 2.26440677993516 | 1708_at | 602897 | ENSG00000109339 | 25209 | 5602 | NM_002753 /// NM_138980 /// NM_138981 /// NM_138982 |  | protein amino acid phosphorylation /// signal transduction /// JNK cascade | protein serine/threonine kinase activity /// JUN kinase activity /// MAP kinase activity /// MAP kinase kinase activity /// ATP binding /// transferase activity | --- | Apoptosis /// Apoptosis_GenMAPP /// G13_Signaling_Pathway /// Integrin-mediated_cell_adhesion_KEGG /// MAPK_Cascade /// Wnt_signaling | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_GenMAPP/Hs_Apoptosis_GenMAPP.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G13_Signaling_Pathway/Hs_G13_Signaling_Pathway.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Integrin-mediated_cell_adhesion_KEGG/Hs_Integrin-mediated_cell_adhesion_KEGG.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_MAPK_Cascade/Hs_MAPK_Cascade.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm
U07620 | mitogen-activated protein kinase 10 | MAPK10 | 3_2 | 0.005255211 | decreased | 1.254464097592614 | 1709_g_at | 602897 | ENSG00000109339 | 25209 | 5602 | NM_002753 /// NM_138980 /// NM_138981 /// NM_138982 |  | protein amino acid phosphorylation /// signal transduction /// JNK cascade | protein serine/threonine kinase activity /// JUN kinase activity /// MAP kinase activity /// MAP kinase kinase activity /// ATP binding /// transferase activity | --- | Apoptosis /// Apoptosis_GenMAPP /// G13_Signaling_Pathway /// Integrin-mediated_cell_adhesion_KEGG /// MAPK_Cascade /// Wnt_signaling | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_GenMAPP/Hs_Apoptosis_GenMAPP.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G13_Signaling_Pathway/Hs_G13_Signaling_Pathway.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Integrin-mediated_cell_adhesion_KEGG/Hs_Integrin-mediated_cell_adhesion_KEGG.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_MAPK_Cascade/Hs_MAPK_Cascade.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm
HG884-HT884 | --- | --- | 6_1 | 0.018023021 | decreased | 2.304932876433048 | 1725_s_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
D00003 | cytochrome P450, family 3, subfamily A, polypeptide 4 | CYP3A4 | 10_1 | 0.011795715 | decreased | 1.452198184961488 | 1755_i_at | 124010 | ENSG00000160868 | 442527 | 1576 | /// NM_017460 |  | electron transport /// lipid metabolism /// xenobiotic metabolism /// xenobiotic metabolism /// transport | monooxygenase activity /// oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen /// oxygen binding /// unspecific monooxygenase activity /// quinine 3-monooxygenase activity /// testosterone 6-beta-hydroxylase activity | membrane fraction /// membrane fraction /// endoplasmic reticulum /// microsome /// microsome /// membrane | Irinotecan_pathway_PharmGKB /// Fatty acid metabolism /// gamma-Hexachlorocyclohexane degradation /// Tryptophan metabolism | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Irinotecan_pathway_PharmGKB/Hs_Irinotecan_pathway_PharmGKB.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00071+1.14.14.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00361+1.14.14.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+1.14.14.1
L36463 | [NAME] and Rab interactor 1 | RIN1 | 6_1 | 0.016873591 | decreased | 2.361083349594566 | 1777_at | 605965 | ENSG00000174791 | 1030 | 9610 | NM_004292 |  | endocytosis /// intracellular signaling cascade | GTPase activator activity /// protein binding | cytoskeleton /// plasma membrane | --- | ---
M25269 | ELK1, member of ETS oncogene family | ELK1 | 5_10 | 0.012105253 | increased | 1.617596954590983 | 1781_at | 311040 | ENSG00000126767 | 181128 | 2002 | NM_005229 |  | transcription /// regulation of transcription, DNA-dependent | transcription factor activity | nucleus | MAPK_Cascade | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_MAPK_Cascade/Hs_MAPK_Cascade.htm
U07418 | mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) | MLH1 | 10_1 | 0.005719444 | decreased | 1.947283690421224 | 1850_at | 114030 /// 114500 /// 120436 /// 158320 /// 276300 | ENSG00000076242 | 195364 | 4292 | NM_000249 |  | mismatch repair /// cell cycle /// negative regulation of cell cycle | ATP binding | nucleus | Ovarian_Infertility_Genes | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Ovarian_Infertility_Genes/Hs_Ovarian_Infertility_Genes.htm
AF015950 | telomerase reverse transcriptase | TERT | 10_1 | 0.033537259 | decreased | 1.476463589225402 | 1869_at | 187270 | ENSG00000164362 | 492203 | 7015 | NM_003219 /// NM_198253 /// NM_198254 /// NM_198255 |  | RNA-dependent DNA replication /// telomerase-dependent telomere maintenance | DNA binding /// telomeric template [NAME] reverse transcriptase activity /// telomeric template [NAME] reverse transcriptase activity /// RNA binding /// RNA-directed DNA polymerase activity /// transferase activity /// telomeric DNA binding | chromosome, telomeric region /// nucleus /// telomerase holoenzyme complex | --- | ---
U83660 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | [NAME] | 10_1 | 0.028587837 | decreased | 1.422118530913327 | 1931_at | 605250 | ENSG00000125257 | 508423 | 10257 | NM_005845 |  | ion transport | chloride channel activity /// ATP binding /// 15-hydroxyprostaglandin dehydrogenase (NAD+) activity /// ATPase activity /// ATPase activity, coupled to transmembrane movement of substances | membrane /// integral to membrane | --- | ---
AB004922 | SMAD, mothers against DPP homolog 3 (Drosophila) | SMAD3 | 5_10 | 0.001917645 | increased | 1.351221974831991 | 1950_s_at | 603109 | ENSG00000166949 | 36915 | 4088 | NM_005902 |  | transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// transforming growth factor beta receptor signaling pathway | transcription factor activity | intracellular | --- | ---
U14658 | PMS2 postmeiotic segregation increased 2 (S. cerevisiae) /// PMS2-C terminal-like | PMS2 /// PMS2CL | 3_1 | 0.039096601 | decreased | 1.319648883944363 | 2015_s_at | 114500 /// 276300 /// 600259 /// 608623 | ENSG00000122512 | 449374 | 441194 /// 5395 | /// NM_000535 |  | mismatch repair /// cell cycle /// negative regulation of cell cycle | DNA binding /// ATP binding | nucleus /// nucleus | --- | ---
M29870 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | RAC1 | 6_1 | 0.009407786 | decreased | 2.182555713690906 | 2050_s_at | 602048 | ENSG00000136238 | 413812 | 5879 | NM_006908 /// NM_018890 /// NM_198829 |  | small GTPase mediated signal transduction /// protein transport | GTP binding | --- | G13_Signaling_Pathway /// Integrin-mediated_cell_adhesion_KEGG /// Wnt_signaling | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G13_Signaling_Pathway/Hs_G13_Signaling_Pathway.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Integrin-mediated_cell_adhesion_KEGG/Hs_Integrin-mediated_cell_adhesion_KEGG.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm
M60724 | --- | --- | 4_3 | 0.011893329 | decreased | 1.494354368913703 | 238_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
L41067 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | NFATC3 | 6_1 | 0.032386921 | decreased | 1.489631342102635 | 250_at | 602698 | ENSG00000072736 | 341716 | 4775 | NM_004555 /// NM_173163 /// NM_173164 /// NM_173165 |  | regulation of transcription from RNA polymerase II promoter /// inflammatory response | transcription factor activity /// transcription coactivator activity | nucleus | --- | ---
M23533 | adrenergic, alpha-2A-, receptor | ADRA2A | 3_2 | 0.000335178 | decreased | 1.776450023518566 | 264_at | 104210 | ENSG00000150594 | 249159 | 150 | NM_000681 |  | activation of MAPK /// cell motility /// signal transduction /// G-protein coupled receptor protein signaling pathway /// negative regulation of adenylate cyclase activity /// [NAME] protein signal transduction /// Rho protein signal transduction /// positive regulation of cell proliferation /// actin cytoskeleton organization and biogenesis | rhodopsin-like receptor activity /// receptor activity /// adrenoceptor activity /// alpha2-adrenergic receptor activity /// potassium channel regulator activity | plasma membrane /// integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Monoamine_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Monoamine_GPCRs/Hs_Monoamine_GPCRs.htm
L40387 | 2'-5'-oligoadenylate synthetase-like | OASL | 1_10 | 0.002056163 | increased | 1.316128580961889 | 269_at | 603281 | ENSG00000135114 | 118633 | 8638 | NM_003733 /// NM_198213 |  | protein modification /// immune response | DNA binding /// double-stranded RNA binding /// ATP binding /// transferase activity /// thyroid hormone receptor binding | nucleolus /// cytoplasm | --- | ---
L25931 | lamin B receptor | LBR | 8_1 | 0.014282804 | decreased | 1.756621851166878 | 288_s_at | 169400 /// 215140 /// 600024 | ENSG00000143815 | 435166 | 3930 | NM_002296 /// NM_194442 |  | --- | DNA binding /// receptor activity /// lamin binding | nucleus /// integral to nuclear inner membrane /// membrane /// integral to membrane | --- | ---
[NAME] | high-mobility group nucleosome binding domain 1 | HMGN1 | 7_1 | 0.025544242 | decreased | 1.351268446546378 | 306_s_at | 163920 | ENSG00000198875 | 356285 | 3150 | NM_004965 |  | --- | DNA binding /// DNA binding /// RNA polymerase II transcription factor activity /// positive transcription elongation factor activity | chromatin /// chromatin /// nucleus | --- | ---
W26214 | Glutaminase | GLS | 10_1 | 0.040970675 | decreased | 1.203431221003979 | 31357_at | 138280 | ENSG00000115419 | 116448 | 2744 | NM_014905 |  | glutamine catabolism | glutaminase activity /// hydrolase activity | mitochondrion | Glutamate metabolism /// D-Glutamine and D-glutamate metabolism /// Nitrogen metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00251+3.5.1.2 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00471+3.5.1.2 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00910+3.5.1.2
[NAME] | --- | --- | 10_1 | 0.030023938 | decreased | 1.413025711110816 | 31371_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
W28546 | --- | --- | 1_10 | 0.006353835 | increased | 1.575945926602689 | 31375_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AF101441 | bone morphogenetic protein 10 | BMP10 | 5_10 | 0.042473181 | increased | 2.073355416335124 | 31399_at | 608748 | ENSG00000163217 | 158317 | 27302 | NM_014482 |  | cell-cell signaling /// embryonic development /// cardioblast differentiation /// embryonic heart tube development /// growth /// regulation of cell proliferation | cytokine activity /// growth factor activity | extracellular region | --- | ---
AE000659 | T cell receptor V-alpha 24 (TCRA) | --- | 5_10 | 0.019255557 | increased | 1.327345809438442 | 31429_at | --- | --- | 428848 | --- | --- |  | --- | --- | --- | --- | ---
AB019392 | eukaryotic translation initiation factor 3, subunit 12 | EIF3S12 | 8_1 | 0.013529471 | decreased | 1.677304917198221 | 31492_at | --- | ENSG00000178982 | 314359 | 27335 | NM_013234 |  | protein biosynthesis /// translational initiation | translation initiation factor activity | nucleus | --- | ---
[NAME] | UDP-galactose-4-epimerase | GALE | 6_1 | 0.020042856 | decreased | 1.893207705099268 | 31598_s_at | 230350 /// 606953 | ENSG00000117308 | 76057 | 2582 | NM_000403 /// NM_001008216 |  | carbohydrate metabolism /// galactose metabolism /// nucleotide-sugar metabolism | UDP-glucose 4-epimerase activity /// UDP-glucose 4-epimerase activity /// isomerase activity | --- | Galactose metabolism /// Nucleotide sugars metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00052+5.1.3.2 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00520+5.1.3.2
U94902 | CD44 antigen (homing function and Indian blood group system) | CD44 | 5_10 | 0.038748734 | increased | 2.033274976258841 | 31616_r_at | 107269 | [NAME] | 502328 | 960 | NM_000610 /// NM_001001389 /// NM_001001390 /// NM_001001391 /// NM_001001392 |  | cell adhesion /// cell-matrix adhesion /// cell-cell adhesion | receptor activity /// protein binding /// collagen binding /// hyaluronic acid binding /// hyaluronic acid binding | integral to plasma membrane /// membrane /// integral to membrane | --- | ---
AJ243542 | chemokine (C-C motif) ligand 27 | CCL27 | 6_1 | 0.043570626 | decreased | 1.731412244860189 | 31644_at | 604833 | ENSG00000187186 | 459590 | 10850 | NM_006664 |  | chemotaxis /// immune response /// cell-cell signaling | chemokine activity | extracellular region | --- | ---
AB023217 | [NAME], heavy polypeptide 15 | MYH15 | 1_10 | 0.03583358 | increased | 1.82753483553146 | 31652_at | --- | ENSG00000144821 | 225968 | 22989 | XM_036988 |  | --- | motor activity /// actin binding /// ATP binding | [NAME] | --- | ---
AB016902 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | MLLT4 | 5_10 | 0.040009732 | increased | 1.829235504625506 | 31663_at | 159559 | ENSG00000130396 | 549055 | 4301 | NM_005936 |  | cell adhesion /// cell adhesion /// signal transduction /// signal transduction /// cell-cell signaling | motor activity /// protein binding /// protein C-terminus binding | intercellular junction /// myosin | --- | ---
D55696 | legumain | LGMN | 6_1 | 0.037359144 | decreased | 1.485106049407772 | 317_at | 602620 | ENSG00000100600 | 18069 | 5641 | NM_001008530 /// NM_005606 |  | proteolysis and peptidolysis | legumain activity /// legumain activity | lysosome | --- | ---
U91510 | ectonucleoside triphosphate diphosphohydrolase 2 | ENTPD2 | 1_10 | 0.047951619 | increased | 1.374539672685612 | 31727_at | 602012 | ENSG00000054179 | 123036 | 954 | NM_001246 /// NM_203468 |  | --- | magnesium ion binding /// hydrolase activity /// ATPase activity, uncoupled | integral to membrane | Purine metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+3.6.1.3
U31099 | prostaglandin D2 receptor (DP) | PTGDR | 5_10 | 0.029703312 | increased | 1.435335223867945 | 31782_at | 604687 /// 607277 | ENSG00000168229 | 306831 | 5729 | NM_000953 |  | signal transduction /// G-protein coupled receptor protein signaling pathway | rhodopsin-like receptor activity /// receptor activity /// prostaglandin D receptor activity /// thromboxane receptor activity | integral to membrane | Prostaglandin_synthesis_regulation /// GPCRDB_Class_A_Rhodopsin-like /// Small_ligand_GPCRs | [NAME] /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// [NAME]
M14564 | cytochrome P450, family 17, subfamily A, polypeptide 1 | CYP17A1 | 10_1 | 0.01836799 | decreased | 1.807017738068796 | 31789_at | 202110 | ENSG00000148795 | 438016 | 1586 | NM_000102 |  | electron transport /// C21-steroid hormone biosynthesis /// transport /// sex differentiation | monooxygenase activity /// steroid 17-alpha-monooxygenase activity /// oxygen binding | endoplasmic reticulum /// microsome /// membrane | Glucocorticoid_Mineralocorticoid_Metabolism /// Steroid_Biosynthesis /// C21-Steroid hormone metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Glucocorticoid_Mineralocorticoid_Metabolism/Hs_Glucocorticoid_Mineralocorticoid_Metabolism.htm /// www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Steroid_Biosynthesis/Hs_Steroid_Biosynthesis.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00140+1.14.99.9
D64142 | H1 histone family, member X | H1FX | 10_1 | 0.037785118 | decreased | 1.663781363206679 | 318_at | 602785 | ENSG00000184897 | 75307 | 8971 | NM_006026 |  | nucleosome assembly /// chromosome organization and biogenesis (sensu [NAME]) | DNA binding | nucleosome /// nucleus /// chromosome | --- | ---
D86979 | KIAA0226 | KIAA0226 | 5_9 | 0.034408114 | increased | 1.447666892367694 | 31802_at | --- | ENSG00000145016 | 478868 | 9711 | XM_032901 |  | --- | --- | --- | --- | ---
U78575 | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | PIP5K1A | 1_8 | 0.035408486 | increased | 1.956987349201617 | 31833_at | 603275 | ENSG00000143398 | 546316 | 8394 | NM_003557 |  | glycerophospholipid metabolism /// signal transduction /// phosphorylation | kinase activity /// 1-phosphatidylinositol-4-phosphate 5-kinase activity /// 1-phosphatidylinositol-4-phosphate 5-kinase activity /// transferase activity | --- | --- | ---
M94151 | catenin (cadherin-associated protein), alpha 2 | CTNNA2 | 4_1 | 0.026310986 | decreased | 1.303576981815024 | 31841_at | 114025 | ENSG00000066032 | 167368 | 1496 | NM_004389 |  | cell adhesion /// cell adhesion | structural molecule activity /// structural constituent of cytoskeleton /// protein binding /// cadherin binding | [NAME] | --- | ---
AJ224819 | ret finger protein 2 | [NAME] | 4_4 | 0.026867806 | decreased | 2.102074517844668 | 31851_at | 605661 | ENSG00000198553 | 436922 | 10206 | NM_001007278 /// NM_005798 /// NM_052811 /// NM_213590 |  | potassium ion transport /// cell cycle /// morphogenesis /// protein ubiquitination /// positive regulation of I-kappaB kinase/NF-kappaB cascade /// negative regulation of cell cycle | ubiquitin-protein ligase activity /// signal transducer activity /// voltage-gated potassium channel activity /// protein binding /// zinc ion binding | ubiquitin ligase complex /// voltage-gated potassium channel complex /// membrane | --- | ---
AF053977 | CDC23 (cell division cycle 23, yeast, homolog) | CDC23 | 4_4 | 0.03838969 | decreased | 1.501420603021925 | 31877_at | 603462 | ENSG00000094880 | 153546 | 8697 | NM_004661 |  | regulation of cell cycle /// G1 phase of mitotic cell cycle /// cytokinesis /// ubiquitin-dependent protein catabolism /// ubiquitin cycle /// mitotic metaphase plate congression /// regulation of exit from mitosis /// regulation of mitotic metaphase/anaphase transition | ubiquitin-protein ligase activity /// binding | anaphase-promoting complex | --- | ---
AJ005016 | ATP-binding cassette, sub-family F (GCN20), member 2 | ABCF2 | 1_10 | 0.012442323 | increased | 1.348979918576724 | 31878_at | --- | ENSG00000033050 | 438823 | 10061 | NM_005692 /// NM_007189 |  | transport | nucleotide binding /// transporter activity /// ATP binding /// ATP binding /// ATPase activity | mitochondrial membrane /// ATP-binding cassette (ABC) transporter complex | --- | ---
L40399 | mutL homolog 3 (E. coli) | MLH3 | 8_1 | 0.028908486 | decreased | 1.652587772148036 | 31884_at | 114500 /// 604395 | ENSG00000119684 | 279843 | 27030 | NM_014381 |  | mismatch repair /// meiotic recombination | satellite DNA binding /// protein binding /// ATP binding | nucleus | --- | ---
M64572 | protein tyrosine phosphatase, non-receptor type 3 | PTPN3 | 7_1 | 0.023857226 | decreased | 2.705081527673027 | 31885_at | 176877 | ENSG00000070159 | 436429 | 5774 | NM_002829 |  | protein amino acid dephosphorylation /// protein amino acid dephosphorylation | protein tyrosine phosphatase activity /// protein tyrosine phosphatase activity /// receptor activity /// structural molecule activity /// structural molecule activity /// cytoskeletal protein binding /// hydrolase activity | nucleus /// cytoplasm /// cytoplasm /// cytoskeleton /// membrane | --- | ---
U67733 | phosphodiesterase 2A, cGMP-stimulated | PDE2A | 7_1 | 0.050248402 | decreased | 1.521773108900525 | 31904_at | 602658 | ENSG00000186642 | 503163 | 5138 | NM_002599 |  | signal transduction | 3',5'-cyclic-nucleotide phosphodiesterase activity /// cGMP-stimulated cyclic-nucleotide phosphodiesterase activity /// hydrolase activity | membrane | --- | ---
AI344681 | ATP-binding cassette, sub-family A (ABC1), member 1 | ABCA1 | 1_10 | 0.032687316 | increased | 1.520074547438135 | 32000_g_at | 105150 /// 143890 /// 205400 /// 600046 /// 604091 | ENSG00000165029 | 429294 | 19 | NM_005502 |  | lipid metabolism /// transport /// transport /// steroid metabolism /// cholesterol metabolism | nucleotide binding /// ATP binding /// ATP binding /// anion transporter activity /// sterol transporter activity /// ATPase activity | membrane fraction /// integral to plasma membrane | Statin_Pathway_PharmGKB | [NAME]
AF051767 | GDNF family receptor alpha 3 | GFRA3 | 10_1 | 0.030972463 | decreased | 1.047394872975696 | 32002_at | 605710 | ENSG00000146013 | 58042 | 2676 | NM_001496 |  | signal transduction /// peripheral nervous system development | receptor activity /// receptor binding | extrinsic to membrane | --- | ---
AL031118 | similar to dJ153G14.3 (novel C2H2 type Zinc Finger protein) | LOC346157 | 10_1 | 0.036451334 | decreased | 1.773534781105635 | 32023_at | --- | ENSG00000124613 | 534636 | 346157 | XM_294077 |  | --- | nucleic acid binding /// zinc ion binding | nucleus | --- | ---
Y11306 | transcription factor 7-like 2 (T-cell specific, HMG-box) | TCF7L2 | 6_1 | 0.04064758 | decreased | 1.163929505901268 | 32025_at | 602228 | ENSG00000148737 | 501080 | 6934 | NM_030756 |  | regulation of cell cycle /// establishment and/or maintenance of chromatin architecture /// transcription /// regulation of transcription from RNA polymerase II promoter /// signal transduction /// regulation of Wnt receptor signaling pathway | transcription factor activity /// RNA polymerase II transcription factor activity | nucleus | --- | ---
D89859 | zinc finger protein 161 homolog (mouse) | ZFP161 | 7_1 | 0.021821054 | decreased | 1.363850766401575 | 32075_at | 602126 | ENSG00000198081 | 156000 | 7541 | NM_003409 |  | negative regulation of transcription from RNA polymerase II promoter /// transcription /// regulation of transcription, DNA-dependent | DNA binding /// protein binding /// zinc ion binding | nucleus | --- | ---
D42055 | neural precursor cell expressed, developmentally down-regulated 4 | NEDD4 | 10_1 | 0.044849505 | decreased | 1.003981980653869 | 32078_at | 602278 | ENSG00000069869 | 1565 | 4734 | NM_006154 /// NM_198400 |  | ubiquitin cycle | ubiquitin-protein ligase activity /// ligase activity | intracellular | Proteasome_Degradation | [NAME]
AB007913 | chromodomain helicase DNA binding protein 5 | CHD5 | 3_2 | 0.007292074 | decreased | 1.566065595498696 | 32093_at | --- | [NAME] | 522898 | 26038 | NM_015557 |  | chromatin assembly or disassembly /// chromatin remodeling /// transcription /// regulation of transcription, DNA-dependent /// regulation of transcription, DNA-dependent /// neurogenesis /// protein ubiquitination /// chromatin modification | DNA binding /// chromatin binding /// chromatin binding /// helicase activity /// ubiquitin-protein ligase activity /// ATP binding /// ATP-dependent helicase activity /// zinc ion binding /// hydrolase activity | ubiquitin ligase complex /// chromatin /// nucleus /// nucleus | --- | ---
M20786 | serine (or cysteine) proteinase inhibitor, clade F ([NAME], pigment epithelium derived factor), member 2 | SERPINF2 | 6_1 | 0.048958472 | decreased | 1.400825654901408 | 32103_at | 262850 | ENSG00000167711 | 159509 | 5345 | NM_000934 |  | acute-phase response | serine-type endopeptidase inhibitor activity /// protein binding | extracellular region /// Golgi apparatus | Blood_Clotting_Cascade | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Blood_Clotting_Cascade/Hs_Blood_Clotting_Cascade.htm
AB002405 | [NAME] | EVER1 | 6_1 | 0.033281143 | decreased | 1.963050153162378 | 32116_at | 226400 /// 605828 | ENSG00000141524 | 16165 | 11322 | NM_007267 |  | --- | --- | integral to membrane | --- | ---
AA928996 | THO complex 2 | [NAME] | 6_1 | 0.028600907 | decreased | 1.451176545512989 | 32125_at | 300395 | ENSG00000125676 | 149991 | 57187 | NM_020449 |  | nuclear mRNA splicing, via spliceosome /// mRNA-nucleus export /// transport | RNA binding | nucleus | --- | ---
Y13710 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | CCL18 | 1_9 | 0.034260885 | increased | 1.611942983542752 | 32128_at | 603757 | ENSG00000006074 | 143961 | 6362 | NM_002988 |  | chemotaxis /// inflammatory response /// signal transduction /// cell-cell signaling /// sensory perception /// response to biotic stimulus /// antimicrobial humoral response (sensu Vertebrata) | chemokine activity | extracellular region | --- | ---
AB020682 | F-box protein 21 | FBXO21 | 10_1 | 0.030246714 | decreased | 1.453234628486362 | 32169_at | 609095 | ENSG00000135108 | 159699 | 23014 | NM_015002 /// NM_033624 |  | ubiquitin-dependent protein catabolism /// ubiquitin cycle | ubiquitin-protein ligase activity | ubiquitin ligase complex | --- | ---
AL050118 | fatty acid desaturase 2 | FADS2 | 9_1 | 0.033744826 | decreased | 1.471536832089136 | 32190_at | 606149 | ENSG00000134824 | 502745 | 9415 | NM_004265 |  | fatty acid biosynthesis /// fatty acid desaturation /// fatty acid desaturation | oxidoreductase activity /// oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water | membrane fraction /// integral to plasma membrane /// membrane | --- | ---
U20489 | protein tyrosine phosphatase, receptor type, O | PTPRO | 1_10 | 0.043103783 | increased | 1.402724450952379 | 32199_at | 600579 | ENSG00000151490 | 160871 | 5800 | NM_002848 /// NM_030667 /// NM_030668 /// NM_030669 /// NM_030670 /// NM_030671 |  | protein amino acid dephosphorylation /// protein amino acid dephosphorylation | protein tyrosine phosphatase activity /// protein tyrosine phosphatase activity /// receptor activity /// transmembrane receptor protein tyrosine phosphatase activity /// hydrolase activity | integral to plasma membrane /// integral to membrane | --- | ---
AL050361 | mitochondrial ribosomal protein S18B | MRPS18B | 7_1 | 0.050847329 | decreased | 1.497742395289692 | 32221_at | --- | ENSG00000137330 | 274417 | 28973 | NM_014046 |  | protein biosynthesis | structural constituent of ribosome | mitochondrion /// mitochondrial small ribosomal subunit /// ribosome | --- | ---
AF072810 | bromodomain adjacent to zinc finger domain, 1B | BAZ1B | 4_3 | 0.032434678 | decreased | 1.236755007082145 | 32261_at | 605681 | ENSG00000009954 | 488671 | 9031 | NM_023005 /// NM_032408 |  | transcription /// regulation of transcription, DNA-dependent /// protein ubiquitination | DNA binding /// transcription factor activity /// ubiquitin-protein ligase activity /// zinc ion binding /// zinc ion binding | ubiquitin ligase complex /// nucleus | --- | ---
AL049669 | KIAA0859 | KIAA0859 | 7_1 | 0.040994734 | decreased | 0.9007017799429088 | 32262_at | --- | ENSG00000010165 | 494705 | 51603 | NM_001007239 /// NM_014955 /// NM_015935 |  | --- | S-adenosylmethionine-dependent methyltransferase activity /// transferase activity | --- | --- | ---
M81882 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | GAD2 | 6_1 | 0.010588919 | decreased | 1.927051830373915 | 32280_at | 138275 | ENSG00000136750 | 231829 | 2572 | NM_000818 |  | amino acid metabolism /// glutamate decarboxylation to succinate /// synaptic transmission /// neurotransmitter biosynthesis | glutamate decarboxylase activity /// protein binding /// lyase activity | --- | Biogenic_Amine_Synthesis /// Glutamate metabolism /// Alanine and aspartate metabolism /// beta-Alanine metabolism /// Taurine and hypotaurine metabolism /// Butanoate metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Biogenic_Amine_Synthesis/Hs_Biogenic_Amine_Synthesis.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00251+4.1.1.15 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00252+4.1.1.15 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00410+4.1.1.15 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00430+4.1.1.15 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00650+4.1.1.15
AI341574 | postmeiotic segregation increased 2-like 1 /// postmeiotic segregation increased 2-like 5 /// similar to postmeiotic segregation increased 2-like 2 /// similar to PMS4 homolog mismatch repair protein - human | PMS2L1 /// PMS2L5 /// LOC442589 /// LOC442593 | 10_1 | 0.051914713 | decreased | 1.465900596013857 | 32310_f_at | 605038 | ENSG00000198632 /// ENSG00000123965 /// ENSG00000174384 /// ENSG00000189011 /// ENSG00000188073 /// ENSG00000174368 | 520575 | 442589 /// 442593 /// 5379 /// 5383 | NM_174930 /// XM_377962 /// XM_380025 /// XM_499331 /// XM_499336 |  | mismatch repair | ATP binding /// damaged DNA binding | nucleus | --- | ---
AL022310 | tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34kDa) | TNFSF4 | 1_10 | 0.021981826 | increased | 1.135900109741363 | 32319_at | 603594 | ENSG00000117586 | 181097 | 7292 | NM_003326 |  | immune response /// signal transduction /// cell-cell signaling /// positive regulation of cell proliferation | tumor necrosis factor receptor binding | integral to plasma membrane /// membrane | --- | ---
M16714 | major histocompatibility complex, class I, E | HLA-E | 6_1 | 0.01582883 | decreased | 1.589572707887185 | 32321_at | 143010 | ENSG00000137361 | 381008 | 3133 | NM_005516 |  | antigen presentation, endogenous antigen /// antigen processing, endogenous antigen via MHC class I | MHC class I receptor activity | integral to membrane /// MHC class I protein complex | Proteasome_Degradation | [NAME]
W27519 | tripartite motif-containing 52 | TRIM52 | 3_1 | 0.023758679 | decreased | 1.893767763237704 | 32326_at | --- | ENSG00000183718 | 458412 | 84851 | NM_032765 |  | protein ubiquitination | ubiquitin-protein ligase activity /// zinc ion binding | ubiquitin ligase complex | --- | ---
[NAME] | solute carrier family 17 (sodium phosphate), member 2 | SLC17A2 | 7_1 | 0.044542798 | decreased | 1.598130888169456 | 32373_at | --- | ENSG00000112337 | 19710 | 10246 | NM_005835 |  | phosphate metabolism /// transport /// ion transport /// sodium ion transport | transporter activity /// sodium:phosphate symporter activity /// symporter activity | membrane fraction /// integral to plasma membrane /// integral to membrane | --- | ---
M63154 | gastric intrinsic factor (vitamin B synthesis) | GIF | 4_1 | 0.002428008 | decreased | 1.754058235317216 | 32470_at | 261000 | ENSG00000134812 | 110014 | 2694 | NM_005142 |  | ion transport /// cobalt ion transport | binding /// cobalt ion transporter activity | extracellular space | --- | ---
M11186 | oxytocin, prepro- (neurophysin I) | OXT | 3_2 | 0.001786748 | decreased | 1.763060218408081 | 32472_at | 167050 | ENSG00000101405 | 113216 | 5020 | NM_000915 |  | signal transduction /// parturition | hormone activity /// neurohypophyseal hormone activity | extracellular region | Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
M76676 | G protein-coupled receptor 135 | GPR135 | 4_1 | 0.026233723 | decreased | 1.647636628626161 | 32483_at | 607970 | ENSG00000181619 | 512691 | 64582 | NM_022571 |  | signal transduction /// G-protein coupled receptor protein signaling pathway | rhodopsin-like receptor activity /// receptor activity /// platelet activating factor receptor activity | membrane /// integral to membrane | GPCRDB_Other | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Other/Hs_GPCRDB_Other.htm
L28168 | potassium voltage-gated channel, Isk-related family, member 1 | KCNE1 | 6_1 | 0.018885512 | decreased | 2.408542564605122 | 32496_at | 176261 /// 220400 | ENSG00000180509 | 121495 | 3753 | NM_000219 |  | ion transport /// potassium ion transport /// muscle contraction /// perception of sound /// regulation of heart contraction rate | delayed rectifier potassium channel activity /// potassium channel regulator activity | voltage-gated potassium channel complex /// membrane /// integral to membrane | --- | ---
AF026947 | aldo-keto reductase family 7, member [NAME] (aflatoxin aldehyde reductase) | AKR7A2 | 8_1 | 0.025610558 | decreased | 1.410733849322675 | 32510_at | 603418 | ENSG00000053371 | 512807 | 8574 | NM_003689 |  | carbohydrate metabolism /// aldehyde metabolism | aldehyde reductase activity /// aldo-keto reductase activity /// electron transporter activity | Golgi apparatus | --- | ---
X98296 | ubiquitin specific protease 9, X-linked (fat facets-like, Drosophila) | USP9X | 7_1 | 0.049872154 | decreased | 1.542532269875633 | 32572_at | 300072 | ENSG00000124486 | 77578 | 8239 | NM_004652 /// NM_021906 |  | ubiquitin-dependent protein catabolism /// ubiquitin cycle /// female gamete generation | cysteine-type endopeptidase activity /// ubiquitin thiolesterase activity | --- | --- | ---
AF070629 | RAB2, member RAS oncogene family | RAB2 | 5_10 | 0.052062491 | increased | 2.024484957929836 | 32581_at | 179509 | ENSG00000104388 | 369017 | 5862 | NM_002865 |  | intracellular protein transport /// small GTPase mediated signal transduction | GTP binding | endoplasmic reticulum /// Golgi apparatus | --- | ---
X75252 | prostatic binding protein | PBP | 9_1 | 0.031639587 | decreased | 1.593243811299494 | 32611_at | 604591 | ENSG00000089220 | 433863 | 5037 | NM_002567 |  | --- | serine-type endopeptidase inhibitor activity /// ATP binding /// lipid binding /// phosphatidylethanolamine binding | --- | --- | ---
D28118 | zinc finger protein 161 | ZNF161 | 9_1 | 0.005343412 | decreased | 1.766634847945355 | 32628_at | 606747 | ENSG00000136451 | 463569 | 7716 | NM_007146 |  | transcription /// regulation of transcription from RNA polymerase II promoter /// cellular defense response | DNA binding /// specific RNA polymerase II transcription factor activity /// zinc ion binding | nucleus | --- | ---
U38260 | islet cell autoantigen 1, 69kDa | ICA1 | 10_1 | 0.039806276 | decreased | 1.524824788800943 | 32634_s_at | 147625 | ENSG00000003147 | 487561 | 3382 | NM_004968 /// NM_022307 /// NM_022308 |  | neurotransmitter transport /// regulation of neurotransmitter secretion | --- | Golgi membrane /// cytosol /// membrane /// secretory granule membrane /// synaptic vesicle membrane | --- | ---
AF060902 | vesicle transport through interaction with t-SNAREs homolog 1B (yeast) | VTI1B | 6_1 | 0.024994876 | decreased | 1.935662500686308 | 32647_at | 603207 | ENSG00000100568 | 144868 | 10490 | NM_006370 |  | intracellular protein transport /// vesicle docking during exocytosis /// membrane fusion /// cell proliferation /// vesicle-mediated transport | --- | integral to membrane | --- | ---
AF031548 | Rhesus blood group-associated glycoprotein | RHAG | 4_1 | 0.044177182 | decreased | 1.95735965032354 | 32663_at | 180297 /// 268150 | ENSG00000112077 | 120950 | 6005 | NM_000324 |  | protein complex assembly /// transport /// circulation /// ammonium transport | ammonium transporter activity /// ankyrin binding | plasma membrane /// integral to plasma membrane /// membrane | --- | ---
M58526 | collagen, type IV, alpha 5 (Alport syndrome) | COL4A5 | 10_1 | 0.017259884 | decreased | 2.002078413352813 | 32667_at | 301050 /// 303630 | ENSG00000188153 | 369089 | 1287 | NM_000495 /// NM_033380 /// NM_033381 |  | phosphate transport | extracellular matrix structural constituent | [NAME] /// collagen type IV /// cytoplasm | --- | ---
D86096 | prostaglandin E receptor 3 (subtype EP3) | PTGER3 | 5_10 | 0.008336287 | increased | 1.45248606287832 | 32691_s_at | 176806 | ENSG00000050628 | 445000 | 5733 | NM_000957 /// NM_198712 /// NM_198713 /// NM_198714 /// NM_198715 /// NM_198716 /// NM_198717 /// NM_198718 /// NM_198719 /// NM_198720 |  | transcription, DNA-dependent /// signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein coupled receptor protein signaling pathway /// cell death | rhodopsin-like receptor activity /// receptor activity /// ligand-dependent nuclear receptor activity /// prostaglandin E receptor activity /// prostaglandin E receptor activity /// prostaglandin E receptor activity /// thromboxane receptor activity | nuclear membrane /// plasma membrane /// integral to plasma membrane /// integral to membrane /// integral to membrane | --- | ---
L41827 | [NAME] 1 | NRG1 | 5_10 | 0.026798426 | increased | 1.156691750330307 | 32719_at | 142445 /// 603013 | ENSG00000157168 | 453951 | 3084 | NM_004495 /// NM_013956 /// NM_013957 /// NM_013958 /// NM_013959 /// NM_013960 /// NM_013961 /// NM_013962 /// NM_013964 |  | neurogenesis /// embryonic development /// cell differentiation | receptor binding /// growth factor activity /// growth factor activity /// transmembrane receptor [NAME] activator activity /// receptor tyrosine kinase binding | extracellular region /// membrane /// integral to membrane | --- | ---
AF034091 | mitochondrial ribosomal protein L40 | [NAME] | 8_1 | 0.042999756 | decreased | 1.473514218921723 | 32745_at | 605089 | ENSG00000185608 | 431307 | 64976 | NM_003776 |  | morphogenesis | structural constituent of ribosome | nucleus /// mitochondrion /// mitochondrial ribosome /// ribonucleoprotein complex | --- | ---
AF015451 | [NAME] and FADD-like apoptosis regulator | CFLAR | 5_10 | 0.006218097 | increased | 1.776698172704293 | 32746_at | 603599 | [NAME] | 390736 | 8837 | NM_003879 |  | proteolysis and peptidolysis /// anti-apoptosis /// induction of apoptosis by extracellular signals /// regulation of apoptosis /// positive regulation of I-kappaB kinase/NF-kappaB cascade | signal transducer activity /// protein binding /// caspase activity | --- | --- | ---
AF030249 | enoyl Coenzyme A hydratase 1, peroxisomal | ECH1 | 9_2 | 0.00150635 | decreased | 2.220319320981642 | 32756_at | 600696 | ENSG00000104823 | 196176 | 1891 | NM_001398 |  | generation of precursor metabolites and energy /// lipid metabolism /// fatty acid metabolism /// fatty acid beta-oxidation /// metabolism | catalytic activity /// enoyl-CoA hydratase activity /// isomerase activity | mitochondrion /// peroxisome | --- | ---
AL048308 | [NAME] domain containing 3 | TDRD3 | 3_1 | 0.05046915 | decreased | 1.627102858015688 | 32768_at | --- | ENSG00000083544 | 525061 | 81550 | NM_030794 |  | --- | nucleic acid binding | --- | --- | ---
L10102 | sex determining region Y | SRY | 4_1 | 0.045349397 | decreased | 1.986843247734662 | 32864_at | 480000 | ENSG00000184895 | 1992 | 6736 | NM_003140 |  | transcription /// regulation of transcription, DNA-dependent /// sex differentiation /// male sex determination | DNA binding /// transcriptional activator activity | nucleus | --- | ---
X85106 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | RPS6KA2 | 10_1 | 0.01781297 | decreased | 1.74738866805831 | 32892_at | 601685 | ENSG00000071242 | 147119 | 6196 | NM_001006932 /// NM_021135 |  | protein amino acid phosphorylation /// protein kinase cascade | protein serine/threonine kinase activity /// protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity | nucleus | Ribosomal_Proteins | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Ribosomal_Proteins/Hs_Ribosomal_Proteins.htm
AF053356 | HIV-1 Rev binding protein-like | HRBL | 10_1 | 0.033721772 | decreased | 1.289116982626573 | 32894_at | 604019 | ENSG00000106351 | 521083 | 3268 | NM_006076 |  | regulation of GTPase activity | --- | --- | --- | ---
HG2238-HT2321 | --- | --- | 9_1 | 0.016735861 | decreased | 1.618711398583695 | 329_s_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
M58378 | synapsin I | SYN1 | 5_10 | 0.006748895 | increased | 1.635439049555579 | 32923_r_at | 300491 /// 313440 | ENSG00000008056 | 225936 | 6853 | NM_006950 /// NM_133499 |  | synaptic transmission /// neurotransmitter secretion | [NAME] binding /// transporter activity | synaptic vesicle /// synapse | --- | ---
AF043724 | hepatitis A virus cellular receptor 1 | HAVCR1 | 3_1 | 0.031800559 | decreased | 1.873017343636667 | 33000_at | 147050 /// 606518 | ENSG00000113249 | 129711 | 26762 | NM_012206 |  | cell adhesion | protein binding | --- | --- | ---
M69136 | chymase 1, mast cell | CMA1 | 5_10 | 0.029146943 | increased | 1.999088534042068 | 33024_at | 118938 | ENSG00000092009 | 135626 | 1215 | NM_001836 |  | proteolysis and peptidolysis | chymotrypsin activity /// trypsin activity /// chymase activity | --- | --- | ---
AF076215 | prophet of Pit1, paired-like homeodomain transcription factor | PROP1 | 5_10 | 0.007702984 | increased | 1.756021723885792 | 33086_at | 601538 | ENSG00000175325 | 158301 | 5626 | NM_006261 |  | regulation of transcription, DNA-dependent /// central nervous system development | transcription factor activity /// RNA polymerase II transcription factor activity | nucleus | --- | ---
D67031 | adducin 3 (gamma) | [NAME] | 7_1 | 0.002609761 | decreased | 1.669783151886258 | 33102_at | 601568 | ENSG00000148700 | 501012 | 120 | NM_001121 /// NM_016824 /// NM_019903 |  | --- | structural constituent of cytoskeleton /// calmodulin binding | cytoskeleton /// membrane | --- | ---
U65093 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | CITED2 | 9_1 | 0.051379589 | decreased | 2.419267904074323 | 33113_at | 602937 | ENSG00000164442 | 82071 | 10370 | NM_006079 |  | regulation of transcription from RNA polymerase II promoter | transcription factor activity /// protein binding | nucleus | --- | ---
[NAME] | insulinoma-associated 1 | INSM1 | 4_3 | 0.041164445 | decreased | 1.192946149112612 | 33157_at | 600010 | ENSG00000173404 | 89584 | 3642 | NM_002196 |  | transcription /// regulation of transcription, DNA-dependent | DNA binding /// zinc ion binding | nucleus | --- | ---
T75292 | septin 11 | 2005-09-11 00:00:00 | 5_9 | 0.047319567 | increased | 1.594172428274598 | 33173_g_at | --- | ENSG00000138758 | 128199 | 55752 | NM_018243 |  | cytokinesis /// cell cycle | GTP binding | --- | --- | ---
AB029020 | ubiquitin specific protease 33 | USP33 | 7_1 | 0.038015066 | decreased | 2.551575084530735 | 33219_at | --- | ENSG00000077254 | 480597 | 23032 | NM_015017 /// NM_201624 /// NM_201626 |  | ubiquitin-dependent protein catabolism /// ubiquitin-dependent protein catabolism /// protein deubiquitination /// protein deubiquitination | cysteine-type endopeptidase activity /// ubiquitin thiolesterase activity /// protein binding /// protein binding | cytoplasm /// cytoplasm /// VCB complex /// VCB complex | --- | ---
AB029018 | PDZ domain containing RING finger 3 | PDZRN3 | 7_1 | 0.020332171 | decreased | 1.890617443502524 | 33240_at | --- | ENSG00000121440 | 434900 | 23024 | NM_015009 |  | protein ubiquitination | ubiquitin-protein ligase activity /// protein binding /// zinc ion binding | ubiquitin ligase complex | --- | ---
X89602 | enolase superfamily member 1 | ENOSF1 | 10_1 | 0.033285401 | decreased | 1.314520496942334 | 33264_at | 607427 | ENSG00000132199 | 475848 | 55556 | NM_017512 |  | metabolism | catalytic activity | --- | --- | ---
AF039029 | RNA, U transporter 1 | RNUT1 | 2_3 | 0.040601825 | decreased | 1.733236085677611 | 33342_at | 607902 | ENSG00000169371 | 21577 | 10073 | NM_005701 |  | --- | RNA cap binding | nuclear pore | --- | ---
[NAME] | WD repeat domain 45 | WDR45 | 10_1 | 0.026641167 | decreased | 1.829943435712528 | 33350_s_at | 300526 | ENSG00000196998 | 156701 | 11152 | NM_007075 |  | --- | --- | --- | --- | ---
M92449 | N-acylsphingosine amidohydrolase (acid ceramidase)-like | ASAHL | 10_1 | 0.036039425 | decreased | 1.408842756217495 | 33382_at | 607469 | ENSG00000138744 | 437365 | 27163 | NM_014435 |  | --- | hydrolase activity | --- | --- | ---
AL080155 | WIPI49-like protein 2 | WIPI-2 | 8_1 | 0.028976291 | decreased | 1.537868041635028 | 33392_at | 609225 | ENSG00000157954 | 122363 | 26100 | NM_015610 /// NM_016003 |  | --- | --- | --- | --- | ---
AL050345 | PKD2 interactor, golgi and endoplasmic reticulum associated 1 | PGEA1 | 3_3 | 0.004947248 | decreased | 1.357177348048232 | 33406_at | 607757 | ENSG00000100211 | 334911 | 25776 | NM_001002880 /// NM_015373 |  | protein localization /// negative regulation of Wnt receptor signaling pathway /// negative regulation of Wnt receptor signaling pathway /// negative regulation of transcription, DNA-dependent | beta-catenin binding /// protein self binding | nucleus /// Golgi trans face | --- | ---
U05291 | fibromodulin | FMOD | 6_1 | 0.00838408 | decreased | 1.589471023899772 | 33431_at | 600245 | ENSG00000122176 | 519168 | 2331 | NM_002023 |  | transforming growth factor beta receptor complex assembly | protein binding | extracellular matrix (sensu Metazoa) /// extracellular matrix ([NAME]) | --- | ---
AF007551 | [NAME] homolog (S. cerevisiae) | BET1 | 9_3 | 0.008562659 | decreased | 1.678446095567634 | 33434_at | 605456 | ENSG00000105829 | 489132 | 10282 | NM_005868 |  | ER to Golgi transport /// protein transport | --- | Golgi membrane /// endoplasmic reticulum /// integral to membrane | --- | ---
U39487 | Xanthine dehydrogenase | XDH | 5_10 | 0.044607215 | increased | 1.079592131740756 | 33463_at | 278300 /// 607633 | ENSG00000158125 | 250 | 7498 | NM_000379 |  | electron transport | xanthine dehydrogenase activity /// electron transporter activity /// iron ion binding /// oxidoreductase activity /// molybdenum ion binding | --- | --- | ---
X94612 | [NAME], cGMP-dependent, type II | PRKG2 | 6_1 | 0.012211074 | decreased | 1.136182244656347 | 33536_at | 601591 | ENSG00000138669 | 546277 | 5593 | NM_006259 |  | regulation of cell cycle /// protein amino acid phosphorylation /// signal transduction | nucleotide binding /// protein serine/threonine kinase activity /// cGMP-dependent protein kinase activity /// ATP binding /// transferase activity /// 3',5'-cGMP binding | --- | --- | ---
M91467 | 5-hydroxytryptamine (serotonin) receptor 1E | HTR1E | 5_10 | 0.024334436 | increased | 1.30581823594688 | 33607_at | 182132 | ENSG00000168830 | 1611 | 3354 | NM_000865 |  | signal transduction /// G-protein signaling, coupled to cyclic nucleotide second messenger /// synaptic transmission | rhodopsin-like receptor activity /// receptor activity /// serotonin receptor activity | integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// Monoamine_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Monoamine_GPCRs/Hs_Monoamine_GPCRs.htm
[NAME] | zinc finger protein 46 (KUP) | ZNF46 | 3_2 | 0.020028323 | decreased | 2.108795571632694 | 33616_at | 194541 | ENSG00000089775 | 164347 | 7597 | NM_006977 |  | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// protein binding /// zinc ion binding | nucleus | --- | ---
Y14768 | allograft inflammatory factor 1 | AIF1 | 1_10 | 0.047594379 | increased | 1.382993827309148 | 33640_at | 601833 | ENSG00000124655 | 76364 | 199 | NM_001623 /// NM_004847 /// NM_032955 |  | response to stress /// inflammatory response /// cell cycle arrest /// negative regulation of cell proliferation | phosphoprotein phosphatase activity /// calcium ion binding | nucleus | --- | ---
N63574 | sulfotransferase family 4A, member 1 | SULT4A1 | 5_9 | 0.005188734 | increased | 1.810057606349044 | 33712_at | 608359 | ENSG00000130540 | 189810 | 25830 | NM_014351 /// NM_176874 |  | lipid metabolism /// steroid metabolism | sulfotransferase activity /// transferase activity | [NAME] | --- | ---
AB014566 | dishevelled associated activator of morphogenesis 1 | DAAM1 | 7_1 | 0.012897775 | decreased | 1.583112616483623 | 33753_at | 606626 | ENSG00000100592 | 19156 | 23002 | NM_014992 |  | cell organization and biogenesis /// actin cytoskeleton organization and biogenesis | [NAME] binding /// Rho GTPase binding | --- | --- | ---
AB017546 | peroxisomal biogenesis factor 14 | PEX14 | 3_2 | 0.028104708 | decreased | 1.884941031954336 | 33760_at | 214100 /// 601791 | ENSG00000142655 | 149983 | 5195 | NM_004565 |  | protein targeting /// protein transport | --- | peroxisome /// integral to peroxisomal membrane /// membrane | --- | ---
[NAME] | T-cell activation leucine repeat-rich protein | TA-LRRP | 10_1 | 0.024486819 | decreased | 1.396017709625556 | 33771_at | --- | ENSG00000197147 | 482017 | 23507 | NM_015350 |  | --- | --- | --- | --- | ---
U19345 | transcription factor 20 (AR1) | TCF20 | 3_2 | 0.048120623 | decreased | 1.060608805541122 | 33793_at | 603107 | ENSG00000100207 | 475018 | 6942 | NM_005650 /// NM_181492 |  | transcription /// regulation of transcription, DNA-dependent | DNA binding /// transcription coactivator activity | nucleus | Matrix_Metalloproteinases | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Matrix_Metalloproteinases/Hs_Matrix_Metalloproteinases.htm
AI761567 | cell cycle progression 1 | CCPG1 | 4_3 | 0.033771923 | decreased | 1.639758372552329 | 33811_at | --- | ENSG00000128845 | 285051 | 9236 | NM_004748 /// NM_020739 |  | --- | --- | --- | --- | ---
Z14229 | nuclear mitotic apparatus protein 1 | NUMA1 | 2_2 | 0.006297132 | decreased | 2.023491943698373 | 33822_at | 164009 | ENSG00000137497 | 523873 | 4926 | NM_006185 |  | mitotic anaphase /// nuclear organization and biogenesis | structural molecule activity | nucleus /// spindle microtubule | --- | ---
Y12670 | [NAME] receptor overlapping transcript | LEPROT | 6_1 | 0.049817641 | decreased | 1.569517098905035 | 33829_at | --- | ENSG00000116678 | --- | 54741 | NM_017526 |  | --- | --- | integral to plasma membrane | --- | ---
AW026535 | Leptin receptor | LEPR | 7_1 | 0.037697309 | decreased | 1.466206448240104 | 33830_at | 601007 | ENSG00000116678 | 23581 | 3953 | NM_001003679 /// NM_001003680 /// NM_002303 |  | energy reserve metabolism /// cell surface receptor linked signal transduction /// development | [NAME]/interferon-class (D200-domain) cytokine receptor activity | integral to plasma membrane /// membrane | --- | ---
AC002045 | nuclear pore complex interacting protein /// PI-3-kinase-related kinase SMG-1-like /// hypothetical protein LOC283970 /// hypothetical protein LOC339047 /// hypothetical protein 348162 /// pps22-1 protein /// [NAME] protein /// similar to PI-3-kinase-related kinase SMG-1 isoform 1; lambda/iota protein kinase C-interacting protein; phosphatidylinositol 3-kinase-related protein kinase | NPIP /// KIAA0220 /// [NAME] /// [NAME] /// LOC348162 /// [NAME] /// [NAME] /// LOC440345 | 9_2 | 0.010936312 | decreased | 1.394733656374508 | 33836_at | 606406 | ENSG00000183793 /// ENSG00000183426 /// ENSG00000183889 /// ENSG00000196796 /// ENSG00000196993 | 528782 | 283846 /// 283970 /// 339047 /// 348162 /// 388221 /// 399491 /// 440345 /// 9284 | NM_006985 /// XM_290671 /// XM_370939 /// XM_496125 /// XM_496132 /// XM_498469 |  | neuropeptide signaling pathway /// amino acid metabolism | carboxy-lyase activity | membrane /// integral to membrane | --- | ---
Y13374 | CAAX box 1 | CXX1 | 8_1 | 0.024889598 | decreased | 2.157198490493501 | 33856_at | 300213 | ENSG00000134590 | 522789 | 8933 | NM_003928 |  | --- | --- | membrane | --- | ---
U50203 | aldehyde dehydrogenase 9 family, member [NAME] | ALDH9A1 | 7_1 | 0.011382618 | decreased | 1.395139689397902 | 33899_at | 602733 | ENSG00000143149 | 2533 | 223 | NM_000696 |  | aldehyde metabolism /// metabolism | aldehyde dehydrogenase (NAD) activity /// electron transporter activity /// oxidoreductase activity /// aminobutyraldehyde dehydrogenase activity /// 4-trimethylammoniobutyraldehyde dehydrogenase activity | --- | Lysine degradation | www.genome.ad.jp/dbget-bin/show_pathway?MAP00310+1.2.1.47
AJ223349 | HIRA interacting protein 3 | HIRIP3 | 10_1 | 0.035655432 | decreased | 1.483886599849118 | 33918_s_at | 603365 | ENSG00000149929 | 446619 | 8479 | NM_003609 |  | chromatin assembly or disassembly | --- | nucleus | --- | ---
Y15409 | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | SLC37A4 | 10_1 | 0.037293796 | decreased | 1.661712280188469 | 33921_at | 232220 /// 232240 /// 602671 | ENSG00000137700 | 132760 | 2542 | NM_001467 |  | transport | transporter activity /// sugar porter activity | integral to membrane | --- | ---
[NAME] | glutathione peroxidase 4 (phospholipid hydroperoxidase) | GPX4 | 9_1 | 0.039196922 | decreased | 1.843802338955595 | 33931_at | 138322 | ENSG00000167468 | 433951 | 2879 | NM_002085 |  | phospholipid metabolism /// response to oxidative stress /// development | glutathione peroxidase activity /// electron transporter activity /// oxidoreductase activity /// phospholipid-hydroperoxide glutathione peroxidase activity | mitochondrion | Glutathione metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00480+1.11.1.9
AJ223040 | cancer/testis antigen 2 | CTAG2 | 5_10 | 0.04958903 | increased | 1.577601323997266 | 34009_at | 300396 | ENSG00000126890 | 87225 | 30848 | NM_020994 /// NM_172377 |  | --- | --- | integral to membrane | --- | ---
U83171 | chemokine (C-C motif) ligand 22 | CCL22 | 4_1 | 0.005737705 | decreased | 1.749690682835117 | 34041_at | 602957 | ENSG00000102962 | 534347 | 6367 | NM_002990 |  | chemotaxis /// inflammatory response /// signal transduction /// cell-cell signaling /// sensory perception /// response to virus /// antimicrobial humoral response (sensu Vertebrata) | chemokine activity | extracellular space | --- | ---
AF034780 | endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 | EDG5 | 10_1 | 0.034749559 | decreased | 1.500483268729632 | 34086_at | 605111 | [NAME] | 458474 | 9294 | NM_004230 |  | activation of MAPK /// signal transduction /// G-protein coupled receptor protein signaling pathway /// positive regulation of cell proliferation | lysosphingolipid and lysophosphatidic acid receptor activity /// receptor activity /// lipid binding | integral to membrane | S1P_Signaling /// Small_ligand_GPCRs | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_S1P_Signaling/Hs_S1P_Signaling.htm /// [NAME]
AL109678 | similar to RIKEN cDNA B230218L05 gene | LOC390616 | 1_10 | 0.021731286 | increased | 1.260188924153536 | 34114_at | --- | ENSG00000188134 | 531231 | 390616 | XM_372584 |  | --- | --- | --- | --- | ---
M63241 | tyrosinase (oculocutaneous albinism IA) | TYR | 10_1 | 0.03066122 | decreased | 1.166262074092662 | 34155_s_at | 103470 /// 203100 /// 606933 /// 606952 | ENSG00000077498 | 503555 | 7299 | NM_000372 |  | melanin biosynthesis from tyrosine /// eye pigment biosynthesis /// visual perception /// perception of sound /// metabolism | monooxygenase activity /// monophenol monooxygenase activity | Golgi vesicle /// integral to membrane | Tyrosine metabolism /// [NAME] metabolism /// Stilbene, coumarine and lignin biosynthesis /// Alkaloid biosynthesis I | www.genome.ad.jp/dbget-bin/show_pathway?MAP00350+1.14.18.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00740+1.14.18.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00940+1.14.18.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00950+1.14.18.1
S80071 | solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 | SLC6A7 | 1_10 | 0.030930467 | increased | 1.342808142274583 | 34166_at | 606205 | ENSG00000011083 | 241597 | 6534 | NM_014228 |  | neurotransmitter transport /// amino acid transport /// synaptic transmission /// L-proline transport | neurotransmitter:sodium symporter activity /// amino acid transporter activity /// symporter activity | membrane fraction /// integral to plasma membrane /// membrane | --- | ---
AB002445 | DCP2 decapping enzyme homolog (S. cerevisiae) | DCP2 | 8_1 | 0.011306007 | decreased | 1.138365814742828 | 34191_at | --- | ENSG00000172795 | 443875 | 167227 | NM_152624 |  | mRNA catabolism, nonsense-mediated decay | RNA binding /// hydrolase activity /// manganese ion binding | nucleus | --- | ---
AB020676 | KIBRA protein | KIBRA | 7_1 | 0.050350686 | decreased | 1.639149591296409 | 34213_at | --- | ENSG00000113645 | 484047 | 23286 | NM_015238 |  | --- | --- | --- | --- | ---
AI352450 | zinc finger protein 278 | ZNF278 | 10_1 | 0.037939674 | decreased | 1.734614963250046 | 34300_at | 605165 | ENSG00000100105 | 517557 | 23598 | NM_014323 /// NM_032050 /// NM_032051 /// NM_032052 |  | transcription /// regulation of transcription, DNA-dependent | DNA binding /// protein binding /// zinc ion binding /// transcriptional repressor activity | nucleus /// nucleus | --- | ---
AB007888 | muscleblind-like (Drosophila) | MBNL1 | 7_1 | 0.029794574 | decreased | 1.583648150840426 | 34306_at | 606516 | ENSG00000152601 | 478000 | 4154 | NM_021038 /// NM_207292 /// NM_207293 /// NM_207294 /// NM_207295 /// NM_207296 /// NM_207297 |  | embryonic development (sensu [NAME]) /// neurogenesis /// muscle development /// embryonic limb morphogenesis /// myoblast differentiation | nucleic acid binding /// double-stranded RNA binding | nucleus /// nucleus /// cytoplasm | --- | ---
Z46606 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3 | SMARCA3 | 7_1 | 0.02329325 | decreased | 1.926828580777976 | 34327_at | 603257 | ENSG00000071794 | 3068 | 6596 | NM_003071 /// NM_139048 |  | transcription /// regulation of transcription, DNA-dependent /// protein ubiquitination /// chromatin modification | DNA binding /// helicase activity /// ubiquitin-protein ligase activity /// ATP binding /// zinc ion binding /// hydrolase activity | ubiquitin ligase complex /// nucleus | --- | ---
D31766 | glucosamine-6-phosphate deaminase 1 | GNPDA1 | 4_3 | 0.03255541 | decreased | 1.717732991604688 | 34332_at | 601798 | ENSG00000113552 | 278500 | 10007 | NM_005471 |  | carbohydrate metabolism /// glucosamine catabolism /// N-acetylglucosamine metabolism /// generation of precursor metabolites and energy /// fertilization (sensu Metazoa) | glucosamine-6-phosphate deaminase activity /// hydrolase activity | --- | --- | ---
U42412 | [NAME], AMP-activated, gamma 1 non-catalytic subunit | PRKAG1 | 7_1 | 0.026885427 | decreased | 1.348204133450968 | 34346_at | 602742 | ENSG00000181929 | 530862 | 5571 | NM_002733 /// NM_212461 |  | protein amino acid phosphorylation /// fatty acid biosynthesis /// signal transduction /// spermatogenesis | cAMP-dependent protein kinase activity /// kinase activity | --- | Fatty_Acid_Synthesis | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Fatty_Acid_Synthesis/Hs_Fatty_Acid_Synthesis.htm
U52960 | SRB7 suppressor of RNA polymerase B homolog (yeast) | SURB7 | 7_1 | 0.041851255 | decreased | 1.094204344585227 | 34357_g_at | 603800 | ENSG00000152944 | 286145 | 9412 | NM_004264 |  | transcription /// regulation of transcription from RNA polymerase II promoter | RNA polymerase II transcription factor activity /// DNA-directed RNA polymerase activity | nucleus /// DNA-directed RNA polymerase II, core complex | --- | ---
U57877 | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | SDHC | 7_1 | 0.039270545 | decreased | 1.937569673259854 | 34385_at | 602413 /// 605373 | ENSG00000143252 | 444472 | 6391 | NM_003001 |  | tricarboxylic acid cycle /// electron transport /// transport | succinate dehydrogenase activity /// electron transporter activity | mitochondrial membrane /// membrane /// integral to membrane | Electron_Transport_Chain /// Krebs-TCA_Cycle | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm /// www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Krebs-TCA_Cycle/Hs_Krebs-TCA_Cycle.htm
AB020655 | SLIT and NTRK-like family, member 3 | SLITRK3 | 10_1 | 0.007288202 | decreased | 2.018022380827202 | 34424_at | --- | ENSG00000121871 | 101745 | 22865 | NM_014926 |  | --- | --- | integral to membrane | --- | ---
AB007940 | RAB GTPase activating protein 1-like | RABGAP1L | 7_1 | 0.020406905 | decreased | 2.31064501852462 | 34445_at | 609238 | ENSG00000152061 | 495391 | 9910 | NM_014857 |  | --- | GTPase activator activity | --- | --- | ---
U62433 | [NAME], nicotinic, alpha polypeptide 4 | CHRNA4 | 6_1 | 0.048259237 | decreased | 2.864015941991515 | 34447_at | 118504 /// 188890 /// 600513 | ENSG00000101204 | 10734 | 1137 | NM_000744 |  | ion transport /// signal transduction /// synaptic transmission /// neurogenesis | nicotinic acetylcholine-activated cation-selective channel activity /// ion channel activity /// extracellular ligand-gated ion channel activity /// acetylcholine receptor activity | nicotinic acetylcholine-gated receptor-channel complex /// integral to membrane /// postsynaptic membrane | --- | ---
D43945 | transcription factor EC | TFEC | 1_6 | 0.040671904 | increased | 1.929349903193863 | 34470_at | 604732 | ENSG00000105967 | 125962 | 22797 | NM_012252 |  | --- | transcription factor activity /// transcription coactivator activity /// transcription corepressor activity | nucleus | --- | ---
X79780 | RAB11B, member RAS oncogene family | RAB11B | 7_1 | 0.027381103 | decreased | 2.076707488794885 | 34478_at | 604198 | [NAME] | 433888 | 9230 | NM_004218 |  | intracellular protein transport /// small GTPase mediated signal transduction | GTPase activity /// GTP binding | --- | --- | ---
AF016272 | cadherin 16, KSP-cadherin | CDH16 | 1_10 | 0.027519288 | increased | 1.149963847628437 | 34480_at | 603118 | ENSG00000166589 | 513660 | 1014 | NM_004062 |  | cell adhesion /// homophilic cell adhesion | calcium ion binding /// protein binding | membrane /// integral to membrane | --- | ---
AF052109 | CDNA clone IMAGE:5260262, partial cds | --- | 10_1 | 0.026467775 | decreased | 1.616353902529069 | 34524_at | --- | --- | 12473 | --- | --- |  | --- | --- | --- | --- | ---
AB018563 | T-cell leukemia/lymphoma 1B /// T-cell leukemia/lymphoma 6 | TCL1B /// TCL6 | 6_1 | 0.020404735 | decreased | 1.431743329408707 | 34525_at | 603769 /// 604412 | ENSG00000187621 | 510368 | 27004 /// 9623 | NM_004918 /// NM_012468 /// NM_014418 /// NM_020550 /// NM_020552 /// NM_020553 /// NM_020554 /// NM_199206 |  | --- | --- | --- | --- | ---
W73822 | hypothetical protein LOC255458 | LOC255458 | 10_1 | 0.038224283 | decreased | 2.473033223542096 | 34530_at | --- | --- | 348292 | 255458 | --- |  | --- | --- | --- | --- | ---
AC002366 | amelogenin (amelogenesis imperfecta 1, X-linked) | AMELX | 5_10 | 0.003602802 | increased | 1.365834852758017 | 34588_i_at | 300391 /// 301200 | ENSG00000125363 | 46329 | 265 | NM_001142 /// NM_182680 /// NM_182681 |  | development /// bone mineralization /// odontogenesis | extracellular matrix structural constituent /// structural constituent of tooth enamel | extracellular matrix (sensu Metazoa) /// extracellular space | --- | ---
U54644 | [NAME] (mouse) | TUB | 1_10 | 0.035665747 | increased | 1.493535320432499 | 34600_s_at | 601197 | ENSG00000166402 | 231850 | 7275 | NM_003320 /// NM_177972 |  | --- | --- | nucleus /// cytoplasm | --- | ---
X69116 | zinc finger protein 37a (KOX 21) | ZNF37A | 5_10 | 0.034238886 | increased | 1.482272949639643 | 34601_at | --- | ENSG00000075407 | 292575 | 7587 | NM_001007094 /// NM_003421 |  | transcription /// regulation of transcription, DNA-dependent /// regulation of transcription, DNA-dependent | DNA binding /// transcription factor activity /// zinc ion binding | nucleus /// nucleus | --- | ---
[NAME] | tumor protein p53 inducible protein 11 | TP53I11 | 1_10 | 0.047696055 | increased | 1.856580849292431 | 34629_at | --- | ENSG00000175274 | 550494 | 9537 | NM_006034 |  | response to stress /// negative regulation of cell proliferation | --- | --- | --- | ---
U63289 | CUG triplet repeat, RNA binding protein 1 | CUGBP1 | 10_1 | 0.012665036 | decreased | 1.581090483664995 | 34683_at | 601074 | ENSG00000149187 | 530727 | 10658 | NM_006560 /// NM_198700 |  | mRNA splice site selection /// mRNA processing /// germ cell development /// embryonic development /// RNA interference | nucleotide binding /// translation repressor activity, nucleic acid binding /// BRE binding | nucleus /// ribonucleoprotein complex | mRNA_processing_Reactome | [NAME]
AB002357 | [NAME] member 3B | KIF3B | 8_1 | 0.03061013 | decreased | 2.265146512297819 | 34713_at | 603754 | ENSG00000101350 | 369670 | 9371 | NM_004798 |  | microtubule-based movement /// determination of left/right symmetry /// anterograde axon cargo transport | ATP binding /// plus-end-directed microtubule motor activity | plus-end kinesin complex /// microtubule associated complex | --- | ---
M96646 | histidyl-tRNA synthetase | HARS | 10_1 | 0.02604444 | decreased | 1.777231571538133 | 34744_at | 142810 | ENSG00000170445 | 528050 | 3035 | NM_002109 |  | protein biosynthesis /// histidyl-tRNA aminoacylation | histidine-tRNA ligase activity /// ATP binding /// ligase activity | cytoplasm | Histidine metabolism /// Aminoacyl-tRNA biosynthesis | www.genome.ad.jp/dbget-bin/show_pathway?MAP00340+6.1.1.21 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00970+6.1.1.21
AL080111 | NIMA (never in mitosis gene a)-related kinase 7 | NEK7 | 7_1 | 0.02650302 | decreased | 1.65570152286607 | 34752_at | 606848 | ENSG00000151414 | 24119 | 140609 | NM_133494 |  | protein amino acid phosphorylation | magnesium ion binding /// protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity | --- | --- | ---
AF038952 | tubulin-specific chaperone a | TBCA | 9_1 | 0.00913088 | decreased | 2.276773076318172 | 34773_at | --- | ENSG00000171530 | 291212 | 6902 | NM_004607 |  | protein folding /// chaperonin-mediated tubulin folding /// post-chaperonin tubulin folding pathway /// beta-tubulin folding | unfolded protein binding /// chaperone binding | cytoskeleton | --- | ---
W27541 | CDC42 effector protein (Rho GTPase binding) 4 | CDC42EP4 | 10_1 | 0.004697234 | decreased | 1.562661260172324 | 34776_at | 605468 | ENSG00000179604 | 3903 | 23580 | NM_012121 |  | cellular morphogenesis | --- | cytoskeleton | --- | ---
D14678 | [NAME] member C1 | [NAME] | 5_10 | 0.038345635 | increased | 1.241270336690956 | 348_at | 603763 | ENSG00000056678 | 436912 | 3833 | XM_371813 |  | mitotic sister chromatid segregation /// microtubule-based movement | microtubule motor activity /// ATP binding | microtubule associated complex | --- | ---
W26099 | golgi reassembly stacking protein 1, 65kDa | GORASP1 | 4_1 | 0.042635906 | decreased | 1.17245986596473 | 34812_at | 606867 | ENSG00000114745 | 250181 | 64689 | NM_031899 |  | protein transport | protein binding | Golgi apparatus /// membrane | --- | ---
D87442 | nicastrin | NCSTN | 6_1 | 0.047056154 | decreased | 1.749047546468699 | 34835_at | 605254 | ENSG00000162736 | 517249 | 23385 | NM_015331 |  | membrane protein ectodomain proteolysis /// Notch receptor processing /// protein processing /// amyloid precursor protein catabolism /// positive regulation of enzyme activity | protein binding | endoplasmic reticulum /// Golgi apparatus /// integral to plasma membrane | --- | ---
AF112472 | Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta | CAMK2B | 5_10 | 0.023068236 | increased | 2.261167001685885 | 34846_at | 607707 | ENSG00000058404 | 351887 | 816 | NM_001220 /// NM_172078 /// NM_172079 /// NM_172080 /// NM_172081 /// NM_172082 /// NM_172083 /// NM_172084 |  | protein amino acid phosphorylation /// protein amino acid phosphorylation /// signal transduction | protein serine/threonine kinase activity /// calcium- and calmodulin-dependent protein kinase activity /// protein-tyrosine kinase activity /// calmodulin binding /// ATP binding /// transferase activity | --- | Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
AB017644 | ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) | UBE2E3 | 7_1 | 0.026647927 | decreased | 2.146084294806896 | 34850_at | 604151 | ENSG00000170035 | 470804 | 10477 | NM_006357 /// NM_182678 |  | ubiquitin cycle | ubiquitin conjugating enzyme activity /// ubiquitin-protein ligase activity /// ligase activity | --- | Ubiquitin mediated proteolysis | www.genome.ad.jp/dbget-bin/show_pathway?MAP04120+6.3.2.19
D63997 | golgi autoantigen, golgin subfamily a, 3 | [NAME] | 4_3 | 0.017202312 | decreased | 1.878676479818485 | 34861_at | 602581 | ENSG00000090615 | 507333 | 2802 | NM_005895 |  | intra-Golgi transport | transporter activity | Golgi membrane /// Golgi transport complex | --- | ---
AJ223957 | pleckstrin homology, Sec7 and coiled-coil domains 3 | PSCD3 | 10_1 | 0.033230291 | decreased | 1.106317289153656 | 34919_at | 605081 | ENSG00000008256 | 487479 | 9265 | NM_004227 |  | vesicle-mediated transport | ARF guanyl-nucleotide exchange factor activity /// phosphatidylinositol binding /// inositol-1,4,5-triphosphate receptor activity | membrane fraction /// plasma membrane | --- | ---
AA442560 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | APOBEC3G | 5_10 | 0.032923493 | increased | 1.836841761571474 | 34947_at | 607113 | ENSG00000128394 | 474853 | 60489 | NM_021822 |  | RNA metabolism /// innate immune response /// negative regulation of retroviral genome replication | RNA binding /// cytidine deaminase activity /// zinc ion binding /// hydrolase activity /// protein homodimerization activity | nucleus | --- | ---
AA557228 | --- | --- | 1_10 | 0.026305532 | increased | 1.527213607971188 | 34963_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AJ001699 | T, brachyury homolog (mouse) | T | 1_10 | 0.020221163 | increased | 1.589606762456967 | 34966_at | 601397 | ENSG00000164458 | 389457 | 6862 | NM_003181 |  | transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// signal transduction /// mesoderm development /// determination of anterior/posterior axis, embryo | transcription factor activity | nucleus | --- | ---
AL096750 | 5-oxoprolinase (ATP-hydrolysing) | OPLAH | 3_1 | 0.051761683 | decreased | 1.330190973319022 | 34969_s_at | --- | ENSG00000178814 | 305882 | 26873 | NM_017570 |  | --- | catalytic activity /// hydrolase activity /// 5-oxoprolinase (ATP-hydrolyzing) activity | --- | --- | ---
AF013512 | lipopolysaccharide binding protein | LBP | 1_7 | 0.035921058 | increased | 1.479215905843824 | 35013_at | 151990 | ENSG00000129988 | 154078 | 3929 | NM_004139 |  | lipid transport /// acute-phase response /// cellular defense response /// response to pathogenic bacteria /// defense response to bacteria | lipid binding | extracellular space /// integral to membrane | --- | ---
X58401 | Immunoglobulin E heavy chain [NAME] (VH5) | --- | 10_1 | 0.036625981 | decreased | 1.220955418010294 | 35014_at | --- | --- | 532509 | --- | --- |  | --- | --- | --- | --- | ---
U62966 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 | SLC28A1 | 10_1 | 0.020035422 | decreased | 2.286238146466563 | 35037_at | 606207 | ENSG00000156222 | 459187 | 9154 | NM_004213 /// NM_201651 |  | nucleobase, nucleoside, nucleotide and nucleic acid metabolism /// transport /// nucleoside transport | nucleoside binding /// nucleoside transporter activity /// nucleoside:sodium symporter activity | membrane fraction /// integral to plasma membrane /// membrane | --- | ---
AF007136 | Clone 23605 mRNA sequence | --- | 9_1 | 0.045495105 | decreased | 3.845703034496576 | 35052_r_at | --- | --- | 100516 | --- | --- |  | --- | --- | --- | --- | ---
AB002339 | Nedd4 binding protein 3 | N4BP3 | 10_1 | 0.038942895 | decreased | 1.258670667659894 | 35057_at | --- | ENSG00000145911 | 101761 | 23138 | NM_015111 |  | --- | --- | cytoplasm /// membrane | --- | ---
AC005263 | anti-Mullerian hormone | AMH | 10_1 | 0.021820113 | decreased | 2.012950940990059 | 35084_at | 261550 /// 600957 | ENSG00000104899 | 112432 | 268 | NM_000479 |  | Mullerian duct regression /// cell-cell signaling /// gonadal mesoderm development /// sex determination /// sex differentiation | hormone activity /// growth factor activity | extracellular space | --- | ---
S67798 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) | SPAM1 | 6_1 | 0.03750535 | decreased | 1.06463065578979 | 35129_at | 600930 | ENSG00000106304 | 121494 | 6677 | NM_003117 /// NM_153189 |  | carbohydrate metabolism /// carbohydrate metabolism /// cell adhesion /// binding of sperm to zona pellucida /// fusion of sperm to egg plasma membrane | hyalurononglucosaminidase activity /// protein binding /// hydrolase activity, acting on glycosyl bonds | plasma membrane | --- | ---
U03886 | patatin-like phospholipase domain containing 4 | PNPLA4 | 7_1 | 0.013004524 | decreased | 1.379645117383038 | 35173_at | 300102 | ENSG00000006757 | 264 | 8228 | NM_004650 |  | --- | catalytic activity /// nutrient reservoir activity | --- | --- | ---
AB018268 | DDHD domain containing 2 | DDHD2 | 7_1 | 0.044073668 | decreased | 1.618741149345455 | 35177_at | --- | ENSG00000085788 | 434966 | 23259 | NM_015214 |  | --- | metal ion binding | Golgi apparatus | --- | ---
AB018309 | EPM2A (laforin) interacting protein 1 | [NAME] | 10_1 | 0.040491329 | decreased | 1.373742043826472 | 35209_at | 607911 | --- | 28020 | 9852 | NM_014805 |  | --- | --- | --- | --- | ---
X91648 | purine-rich element binding protein A | PURA | 6_1 | 0.010804961 | decreased | 1.290711180085047 | 35221_at | 600473 | ENSG00000185129 | 443121 | 5813 | NM_005859 |  | DNA replication initiation /// transcription /// regulation of transcription, DNA-dependent | single-stranded DNA binding /// RNA polymerase II transcription factor activity, enhancer binding | nucleus | Circadian_Exercise | [NAME]
M91592 | zinc finger protein 76 (expressed in testis) | ZNF76 | 6_1 | 0.048191925 | decreased | 1.216486803228363 | 35225_at | 194549 | ENSG00000065029 | 388024 | 7629 | NM_003427 |  | transcription /// regulation of transcription from RNA polymerase II promoter /// regulation of transcription from RNA polymerase III promoter | DNA binding /// zinc ion binding | nucleus | --- | ---
AI056696 | centrin, EF-hand protein, 3 (CDC31 homolog, yeast) | CETN3 | 9_1 | 0.031190762 | decreased | 1.685322415287726 | 35232_f_at | 602907 | ENSG00000153140 | 528302 | 1070 | NM_004365 |  | cytokinesis /// mitosis /// centrosome cycle | calcium ion binding | centriole | --- | ---
AL096737 | solute carrier family 5 (sodium-dependent vitamin transporter), member 6 | SLC5A6 | 7_1 | 0.020661757 | decreased | 1.736308494860736 | 35256_at | 604024 | ENSG00000138074 | 435735 | 8884 | NM_021095 |  | ion transport /// sodium ion transport | transporter activity /// sodium-dependent multivitamin transporter activity /// biotin binding /// symporter activity | membrane fraction /// integral to plasma membrane /// membrane | --- | ---
N73769 | eukaryotic translation initiation factor 4E binding protein 2 | EIF4EBP2 | 3_1 | 0.011685117 | decreased | 1.583863262677362 | 35263_at | 602224 | ENSG00000148730 | 522995 | 1979 | NM_004096 |  | regulation of translation /// negative regulation of protein biosynthesis /// negative regulation of translational initiation | eukaryotic initiation factor [NAME] binding | --- | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
AF067139 | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) | NDUFS3 | 7_1 | 0.025155004 | decreased | 1.897694586463859 | 35264_at | 256000 /// 603846 | ENSG00000110536 | 502528 | 4722 | NM_004551 |  | electron transport /// mitochondrial electron transport, NADH to ubiquinone | NADH dehydrogenase activity /// NADH dehydrogenase (ubiquinone) activity /// electron carrier activity | membrane fraction /// mitochondrion | Electron_Transport_Chain | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm
Y12226 | adaptor-related protein complex 1, gamma 1 subunit | AP1G1 | 4_1 | 0.02749967 | decreased | 1.709045516946832 | 35274_at | 603533 | ENSG00000166747 | 461253 | 164 | NM_001128 |  | protein complex assembly /// intracellular protein transport /// intracellular protein transport /// endocytosis | transporter activity /// binding | Golgi apparatus /// coated pit /// membrane coat adaptor complex /// clathrin coat of trans-Golgi network vesicle | --- | ---
AF046888 | tumor necrosis factor (ligand) superfamily, member 13 /// tumor necrosis factor (ligand) superfamily, member 12-member 13 | TNFSF13 /// TNFSF12-TNFSF13 | 10_1 | 0.041283692 | decreased | 1.093692274916358 | 35287_at | 604472 | ENSG00000161955 | 54673 | 407977 /// 8741 | NM_003808 /// NM_172087 /// NM_172088 /// NM_172089 |  | immune response /// signal transduction /// positive regulation of cell proliferation | tumor necrosis factor receptor binding | membrane /// integral to membrane | --- | ---
AB007884 | Cdc42 guanine nucleotide exchange factor (GEF) 9 | ARHGEF9 | 5_10 | 0.007884366 | increased | 1.813329513638601 | 35288_at | 300429 | ENSG00000131089 | 54697 | 23229 | NM_015185 |  | --- | --- | --- | --- | ---
M25077 | Sjogren syndrome antigen A2 (60kDa, ribonucleoprotein autoantigen SS-A/Ro) | SSA2 | 6_1 | 0.019823524 | decreased | 1.529391735115982 | 35295_g_at | 600063 | ENSG00000116747 | 288178 | 6738 | NM_004600 |  | transcription from RNA polymerase III promoter | RNA binding | ribonucleoprotein complex | --- | ---
U41654 | Ras-related GTP binding A | RRAGA | 9_1 | 0.0307278 | decreased | 2.427153303722413 | 35316_at | --- | ENSG00000155876 | 432330 | 10670 | NM_006570 |  | --- | --- | nucleus /// cytoplasm | --- | ---
AB014579 | meningioma expressed antigen 5 (hyaluronidase) | MGEA5 | 4_1 | 0.011270592 | decreased | 1.624352364720602 | 35317_at | 604039 | ENSG00000198408 | 500842 | 10724 | NM_012215 |  | glycoprotein catabolism | hyalurononglucosaminidase activity | --- | --- | ---
AB007944 | family with sequence similarity 20, member B | FAM20B | 4_4 | 0.027026509 | decreased | 1.625229660886586 | 35318_at | --- | ENSG00000116199 | 5737 | 9917 | NM_014864 |  | --- | --- | --- | --- | ---
U25435 | CCCTC-binding factor (zinc finger protein) | CTCF | 8_1 | 0.003371279 | decreased | 1.557399672419967 | 35319_at | 604167 | ENSG00000102974 | 368367 | 10664 | NM_006565 |  | negative regulation of transcription from RNA polymerase II promoter /// transcription /// negative regulation of cell cycle /// positive regulation of transcription, DNA-dependent | transcription factor activity /// RNA polymerase II transcription factor activity /// transcription corepressor activity /// zinc ion binding | nucleus | --- | ---
U54559 | eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa | EIF3S3 | 6_1 | 0.028460688 | decreased | 1.910195587732835 | 35327_at | 603912 | ENSG00000147677 | 492599 | 8667 | NM_003756 |  | protein biosynthesis /// regulation of translational initiation | translation initiation factor activity | eukaryotic translation initiation factor 3 complex | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
Y17711 | calcium binding atopy-related autoantigen 1 | CBARA1 | 10_1 | 0.039796759 | decreased | 1.496801350577672 | 35360_at | 605084 | ENSG00000107745 | 524367 | 10367 | NM_006077 |  | defense response | calcium ion binding | intracellular | --- | ---
X16281 | zinc finger protein 44 (KOX 7) | ZNF44 | 6_1 | 0.032267121 | decreased | 1.509022605522707 | 35408_i_at | 194542 | ENSG00000197857 | 24120 | 51710 | NM_016264 |  | transcription /// regulation of transcription, DNA-dependent | nucleic acid binding /// DNA binding /// zinc ion binding | intracellular /// nucleus | --- | ---
AI816796 | hypothetical protein DKFZp586M1120 | DKFZP586M1120 | 6_1 | 0.011149096 | decreased | 1.476888519241028 | 35429_at | --- | ENSG00000171962 | 528889 | 83450 | NM_031294 |  | --- | --- | --- | --- | ---
U29700 | anti-Mullerian hormone receptor, type II | AMHR2 | 10_1 | 0.014751312 | decreased | 1.767697710064036 | 35502_at | 261550 /// 600956 | ENSG00000135409 | 437877 | 269 | NM_020547 |  | Mullerian duct regression /// protein amino acid phosphorylation /// signal transduction /// sex determination /// sex differentiation /// sex differentiation | protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// receptor activity /// receptor activity /// transforming growth factor beta receptor activity /// transmembrane receptor protein serine/threonine kinase signaling protein activity /// ATP binding /// transferase activity /// hormone binding | membrane /// integral to membrane | --- | ---
AF054910 | [NAME] (testicular) | TEKT2 | 3_1 | 0.046674993 | decreased | 1.489392948775964 | 35515_at | 608953 | ENSG00000092850 | 127111 | 27285 | NM_014466 |  | microtubule cytoskeleton organization and biogenesis | structural molecule activity | microtubule | --- | ---
AF042181 | TSPY-like 1 | TSPYL1 | 5_10 | 0.0255331 | increased | 1.184046254136497 | 35553_at | 604714 /// 608800 | ENSG00000189241 | 458358 | 7259 | XM_371844 |  | nucleosome assembly | --- | nucleus | --- | ---
U16997 | RAR-related orphan receptor C | RORC | 10_1 | 0.019828612 | decreased | 1.935553771146136 | 35559_at | 602943 | ENSG00000143365 | 546543 | 6097 | NM_001001523 /// NM_005060 |  | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// steroid hormone receptor activity | nucleus | Nuclear_Receptors | [NAME]
L05500 | adenylate cyclase 1 (brain) | [NAME] | 4_1 | 0.030241098 | decreased | 1.423811579564032 | 35580_at | 103072 | ENSG00000164742 | 192215 | 107 | NM_021116 |  | cAMP biosynthesis /// intracellular signaling cascade | magnesium ion binding /// calmodulin binding /// calcium- and calmodulin-responsive adenylate cyclase activity | integral to membrane | G_Protein_Signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction /// Purine metabolism | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// [NAME] /// [NAME]
AL050148 | Sorting nexin 1 | [NAME] | 6_1 | 0.046859051 | decreased | 0.9852486801954374 | 35645_at | 601272 | ENSG00000028528 | 188634 | 6642 | NM_003099 /// NM_148955 /// NM_152826 |  | intracellular protein transport /// endocytosis /// intracellular signaling cascade | protein transporter activity | Golgi apparatus | --- | ---
Z24459 | mature T-cell proliferation 1 | MTCP1 | 1_10 | 0.016747276 | increased | 1.577159063215708 | 35687_at | 300116 | ENSG00000182712 | 6917 | 4515 | NM_014221 |  | regulation of cell cycle /// cell proliferation | --- | mitochondrion | --- | ---
AF006514 | chromodomain helicase DNA binding protein 2 | CHD2 | 3_1 | 0.004068862 | decreased | 1.897536416286416 | 35700_at | 602119 | ENSG00000173575 | 546244 | 1106 | NM_001271 |  | chromatin assembly or disassembly /// regulation of transcription from RNA polymerase II promoter /// chromosome organization and biogenesis (sensu [NAME]) | chromatin binding /// ATP-dependent DNA helicase activity /// helicase activity /// ATP binding /// hydrolase activity | chromatin /// nucleus | --- | ---
AB011112 | neurobeachin-like 2 | NBEAL2 | 4_1 | 0.011675192 | decreased | 1.284970424585985 | 35763_at | --- | --- | 437043 | 23218 | XM_291064 |  | --- | --- | --- | --- | ---
AI565760 | GABA(A) receptor-associated protein-like 2 | [NAME] | 8_1 | 0.004150281 | decreased | 1.387688092648294 | 35767_at | 607452 | ENSG00000034713 | 461379 | 11345 | NM_007285 |  | protein targeting /// synaptic transmission /// protein transport | protein binding /// beta-tubulin binding /// GABA receptor binding | Golgi apparatus /// plasma membrane | --- | ---
AJ133769 | transportin 3 | TNPO3 | 6_1 | 0.003991597 | decreased | 1.213400717189992 | 35812_at | --- | ENSG00000064419 | 193613 | 23534 | NM_012470 |  | protein transport | receptor activity /// binding | nucleus | --- | ---
AF064603 | dendritic cell protein | GA17 | 7_1 | 0.047979518 | decreased | 1.721428280917936 | 35814_at | --- | ENSG00000149100 | 502244 | 10480 | NM_006360 |  | --- | --- | --- | --- | ---
U88047 | AT rich interactive domain 3A (BRIGHT- like) | ARID3A | 1_7 | 0.030575944 | increased | 1.923972150840684 | 35913_at | 603265 | ENSG00000116017 | 501296 | 1820 | NM_005224 |  | transcription /// regulation of transcription, DNA-dependent | DNA binding /// transcription factor activity | intracellular /// nucleus | --- | ---
L19161 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | EIF2S3 | 1_6 | 0.030900954 | increased | 2.115438901514797 | 35934_at | 300161 | ENSG00000130741 | 539684 | 1968 | NM_001415 |  | protein biosynthesis | translation initiation factor activity /// GTPase activity /// GTP binding | cytosolic small ribosomal subunit (sensu [NAME]) /// eukaryotic translation initiation factor 2 complex | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
AB018317 | KIAA0774 | KIAA0774 | 4_3 | 0.044075276 | decreased | 0.8753511085993724 | 35949_at | --- | ENSG00000132938 | 507630 | 23281 | NM_015233 |  | --- | --- | --- | --- | ---
AL031427 | chromosome 1 open reading frame 41 | C1orf41 | 7_1 | 0.029041539 | decreased | 1.630376119429681 | 36032_at | --- | ENSG00000081870 | 525462 | 51668 | NM_016126 |  | --- | hydrolase activity | --- | --- | ---
U35139 | necdin homolog (mouse) | NDN | 9_1 | 0.028681001 | decreased | 1.587438930359817 | 36073_at | 176270 /// 602117 | ENSG00000182636 | 50130 | 4692 | NM_002487 |  | regulation of cell cycle /// regulation of cell growth /// transcription /// regulation of transcription, DNA-dependent /// neurogenesis /// negative regulation of cell proliferation | DNA binding | nucleus | --- | ---
AF035301 | olfactomedin 1 | OLFM1 | 9_1 | 0.010674389 | decreased | 1.832842608438476 | 36134_at | 605366 | ENSG00000130558 | 522484 | 10439 | NM_006334 /// NM_014279 /// NM_058199 |  | development /// neurogenesis | latrotoxin receptor activity | endoplasmic reticulum /// membrane | --- | ---
W27611 | Splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) | SFPQ | 1_10 | 0.002085974 | increased | 1.77369146749743 | 36226_r_at | 605199 | ENSG00000116560 | 355934 | 6421 | NM_005066 |  | nuclear mRNA splicing, via spliceosome /// RNA splicing | nucleotide binding /// DNA binding /// RNA binding | nucleus | --- | ---
AF043129 | interleukin 7 receptor | IL7R | 5_7 | 0.050099073 | increased | 2.064632643266951 | 36227_at | 146661 /// 600802 | ENSG00000168685 | 362807 | 3575 | NM_002185 |  | regulation of DNA recombination /// immune response /// cell surface receptor linked signal transduction /// antimicrobial humoral response (sensu Vertebrata) | antigen binding /// receptor activity /// hematopoietin/interferon-class (D200-domain) cytokine receptor activity /// interleukin-7 receptor activity | membrane /// integral to membrane | --- | ---
X62167 | peripheral [NAME] protein 2 | PMP2 | 3_2 | 0.000495414 | decreased | 1.821347299035108 | 36272_r_at | 170715 | ENSG00000147588 | 2868 | 5375 | NM_002677 |  | transport | transporter activity /// lipid binding | cytoplasm | --- | ---
U09412 | zinc finger protein 134 (clone pHZ-15) | ZNF134 | 5_10 | 0.014921861 | increased | 1.630422704727747 | 36295_at | 604076 | ENSG00000166680 | 469694 | 7693 | NM_003435 |  | transcription /// regulation of transcription, DNA-dependent | nucleic acid binding /// transcription factor activity /// zinc ion binding | nucleus /// nucleus | --- | ---
X15943 | calcitonin/calcitonin-related polypeptide, alpha | CALCA | 10_1 | 0.03515148 | decreased | 1.802174255750024 | 36300_at | 114130 | ENSG00000110680 | 546242 | 796 | NM_001741 |  | skeletal development /// G-protein signaling, coupled to cAMP nucleotide second messenger /// adenylate cyclase activation /// phospholipase C activation /// positive regulation of cytosolic calcium ion concentration /// cell-cell signaling /// regulation of blood pressure | hormone activity | extracellular space /// soluble fraction /// endoplasmic reticulum | Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
M31651 | sex hormone-binding globulin | SHBG | 1_10 | 0.035599314 | increased | 1.230058725179021 | 36328_at | 182205 | ENSG00000129214 | 46319 | 6462 | NM_001040 |  | hormone transport | androgen binding /// protein homodimerization activity | extracellular region | --- | ---
AI760801 | --- | --- | 1_10 | 0.050400865 | increased | 1.681554062522226 | 36337_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AC004522 | zinc finger with KRAB and SCAN domains 1 | [NAME] | 3_1 | 0.051995632 | decreased | 2.679061301573225 | 36340_at | 601260 | ENSG00000106261 | 423725 | 7586 | NM_003439 |  | transcription /// regulation of transcription, DNA-dependent /// regulation of transcription, DNA-dependent | nucleic acid binding /// transcription factor activity /// transcription factor activity /// zinc ion binding | nucleus /// nucleus | --- | ---
AI688589 | Calcium/calmodulin-dependent serine protein kinase (MAGUK family) | CASK | 5_10 | 0.030789916 | increased | 1.413335360000916 | 36416_g_at | 300172 | ENSG00000147044 | 495984 | 8573 | NM_003688 |  | protein amino acid phosphorylation /// cell adhesion | guanylate kinase activity /// protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// protein binding /// calmodulin binding /// ATP binding /// transferase activity | [NAME] | --- | ---
AB028952 | synaptopodin | SYNPO | 1_10 | 0.029903616 | increased | 1.204363199378617 | 36452_at | 608155 | ENSG00000171992 | 435228 | 11346 | NM_007286 |  | --- | [NAME] binding | cytoskeleton | --- | ---
AF016270 | bromodomain containing 8 | BRD8 | 6_1 | 0.037221191 | decreased | 1.248807672076921 | 36476_at | 602848 | ENSG00000112983 | 519337 | 10902 | NM_006696 /// NM_139199 /// NM_183359 |  | regulation of cell growth /// transcription /// regulation of transcription from RNA polymerase II promoter /// cell surface receptor linked signal transduction /// chromatin modification | transcription factor activity /// ligand-regulated transcription factor activity /// transcription coactivator activity /// thyroid hormone receptor activity | nucleus | --- | ---
AI347155 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | PSMD9 | 10_1 | 0.011725245 | decreased | 1.741148634179057 | 36492_at | 603146 | ENSG00000110801 | 131151 | 5715 | NM_002813 |  | ubiquitin-dependent protein catabolism | protein binding | cytosol /// proteasome regulatory particle (sensu [NAME]) | Proteasome_Degradation | [NAME]
U04209 | microfibrillar-associated protein 1 | MFAP1 | 10_1 | 0.013603089 | decreased | 1.482088555448566 | 36535_at | 600215 | ENSG00000140259 | 61418 | 4236 | NM_005926 |  | --- | extracellular matrix structural constituent | extracellular region /// extracellular matrix ([NAME]) | --- | ---
M92303 | calcium channel, voltage-dependent, beta 1 subunit | CACNB1 | 3_1 | 0.021125509 | decreased | 1.821049802739713 | 36557_at | 114207 | ENSG00000067191 | 635 | 782 | NM_000723 /// NM_199247 /// NM_199248 |  | ion transport /// calcium ion transport /// muscle contraction | voltage-gated calcium channel activity | membrane fraction /// voltage-gated calcium channel complex | Calcium_regulation_in_cardiac_cells | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm
D87470 | KIAA0280 protein | KIAA0280 | 4_1 | 0.047758349 | decreased | 2.944079097979737 | 36612_at | --- | ENSG00000054965 | 475334 | 23201 | XM_370635 |  | --- | --- | --- | --- | ---
X87176 | hydroxysteroid (17-beta) dehydrogenase 4 | HSD17B4 | 9_3 | 0.028683077 | decreased | 2.502531927545243 | 36626_at | 261515 /// 601860 | ENSG00000133835 | 406861 | 3295 | NM_000414 |  | lipid metabolism /// fatty acid metabolism /// metabolism | 3-hydroxyacyl-CoA dehydrogenase activity /// estradiol 17-beta-dehydrogenase activity /// sterol carrier activity /// sterol transporter activity /// oxidoreductase activity /// lyase activity /// isomerase activity | peroxisome | Steroid_Biosynthesis | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Steroid_Biosynthesis/Hs_Steroid_Biosynthesis.htm
AI290480 | olfactomedin-like 1 | OLFML1 | 10_1 | 0.00931139 | decreased | 1.416637763037456 | 36695_at | --- | ENSG00000183801 | 503500 | 283298 | NM_198474 |  | --- | --- | --- | --- | ---
U66684 | ATP-binding cassette, sub-family C (CFTR/MRP), member 10 | ABCC10 | 4_3 | 0.04905647 | decreased | 1.480189775932137 | 36730_at | --- | ENSG00000124574 | 55879 | 89845 | NM_033450 |  | transport | nucleotide binding /// ATP binding /// ATPase activity /// ATPase activity, coupled to transmembrane movement of substances | mitochondrion /// integral to membrane /// inner membrane | --- | ---
S62027 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | GNGT1 | 3_1 | 0.049274857 | decreased | 1.151901433695435 | 36772_at | 189970 | ENSG00000127928 | 552572 | 2792 | NM_021955 |  | signal transduction /// G-protein coupled receptor protein signaling pathway | signal transducer activity | [NAME] complex | G_Protein_Signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
AF025534 | [NAME] receptor, subfamily B (with TM and ITIM domains), member 5 | LILRB5 | 5_9 | 0.044260964 | increased | 1.196226150991218 | 36789_f_at | 604814 | ENSG00000105609 | 306230 | 10990 | NM_006840 |  | immune response /// cell surface receptor linked signal transduction | [NAME] receptor activity | integral to membrane | --- | ---
U64820 | ataxin 3 | ATXN3 | 1_10 | 0.052112796 | increased | 1.721616237726387 | 36819_at | 109150 /// 607047 | ENSG00000066427 | 532632 | 4287 | NM_004993 /// NM_030660 |  | nucleotide-excision repair /// transcription /// regulation of transcription, DNA-dependent /// synaptic transmission /// neurogenesis | --- | nucleoplasm /// cytoplasm | --- | ---
U33052 | protein kinase N2 | PKN2 | 6_1 | 0.011161035 | decreased | 1.977297830035254 | 36835_at | 602549 | ENSG00000065243 | 440833 | 5586 | NM_006256 |  | protein amino acid phosphorylation /// signal transduction /// signal transduction | protein serine/threonine kinase activity /// ATP binding /// transferase activity | intracellular | --- | ---
AB028987 | chromosome 19 open reading frame 7 | C19orf7 | 10_3 | 0.027135959 | decreased | 1.585682622544597 | 36860_at | --- | --- | 104661 | 23211 | XM_028253 |  | --- | nucleic acid binding | --- | --- | ---
M60028 | major histocompatibility complex, class II, DQ beta 1 | HLA-DQB1 | 9_1 | 0.039461435 | decreased | 5.858060419496005 | 36878_f_at | 123400 /// 604305 | --- | 409934 | 3119 | NM_002123 |  | immune response /// immune response /// antigen presentation, exogenous antigen /// antigen processing, exogenous antigen via MHC class II | MHC class II receptor activity /// MHC class II receptor activity | membrane /// membrane /// integral to membrane | --- | ---
AL031846 | chromobox homolog 7 | CBX7 | 9_1 | 0.022812394 | decreased | 2.32472703754466 | 36894_at | 608457 | ENSG00000100307 | 356416 | 23492 | NM_175709 |  | chromatin assembly or disassembly /// transcription /// regulation of transcription, DNA-dependent /// chromatin modification | chromatin binding | chromatin /// nucleus | --- | ---
AF044288 | aryl hydrocarbon receptor nuclear translocator-like | ARNTL | 10_1 | 0.047624109 | decreased | 1.661334670486762 | 36896_s_at | 602550 | ENSG00000133794 | 65734 | 406 | NM_001178 |  | transcription /// regulation of transcription, DNA-dependent /// signal transduction /// circadian rhythm | transcription factor activity /// signal transducer activity | nucleus | Circadian_Exercise | [NAME]
M97287 | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | SATB1 | 7_1 | 0.002904411 | decreased | 2.838609407856536 | 36899_at | 602075 | ENSG00000182568 | 517717 | 6304 | NM_002971 |  | establishment and/or maintenance of chromatin architecture /// regulation of transcription, DNA-dependent | double-stranded DNA binding /// transcription factor activity | nucleus | --- | ---
Z26653 | laminin, alpha 2 (merosin, congenital muscular dystrophy) | LAMA2 | 9_1 | 0.01644716 | decreased | 1.647284622997397 | 36917_at | 156225 /// 607855 | ENSG00000196569 | 200841 | 3908 | NM_000426 |  | muscle development /// regulation of cell adhesion /// regulation of cell migration /// regulation of embryonic development | receptor binding /// structural molecule activity /// protein binding | basement membrane /// laminin-1 | --- | ---
[NAME] | general transcription factor IIIC, polypeptide 2, beta 110kDa | GTF3C2 | 4_1 | 0.016917609 | decreased | 1.900751887700884 | 36932_at | 604883 | ENSG00000115207 | 75782 | 2976 | [NAME] |  | transcription /// transcription from RNA polymerase III promoter | [NAME] polymerase III transcription factor activity /// protein binding | transcription factor [NAME] complex /// nucleus | --- | ---
X94910 | chromosome 12 open reading frame 8 | C12orf8 | 9_3 | 0.013369054 | decreased | 1.777133206897517 | 36945_at | 602287 | ENSG00000089248 | 75841 | 10961 | NM_006817 |  | protein folding /// intracellular protein transport | protein disulfide isomerase activity | endoplasmic reticulum | --- | ---
D16480 | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/[NAME] A hydratase (trifunctional protein), alpha subunit | HADHA | 9_1 | 0.013147915 | decreased | 2.045486822272867 | 36952_at | 600890 | ENSG00000084754 | 516032 | 3030 | NM_000182 |  | lipid metabolism /// fatty acid metabolism /// metabolism | 3-hydroxyacyl-CoA dehydrogenase activity /// acetyl-CoA C-acetyltransferase activity /// enoyl-CoA hydratase activity /// oxidoreductase activity /// long-chain-3-hydroxyacyl-CoA dehydrogenase activity /// lyase activity | mitochondrion | Fatty_Acid_Degradation /// Mitochondrial_fatty_acid_betaoxidation /// Fatty acid biosynthesis (path 2) /// Fatty acid metabolism /// [NAME], leucine and isoleucine degradation /// Lysine degradation /// Tryptophan metabolism /// beta-Alanine metabolism /// Benzoate degradation via CoA ligation /// Propanoate metabolism /// Butanoate metabolism /// [NAME] and pinene degradation | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Fatty_Acid_Degradation/Hs_Fatty_Acid_Degradation.htm /// www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Mitochondrial_fatty_acid_betaoxidation/Hs_Mitochondrial_fatty_acid_betaoxidation.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00062+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00071+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00280+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00310+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00410+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00632+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00640+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00650+4.2.1.17 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00903+4.2.1.17
M23254 | calpain 2, (m/II) large subunit | CAPN2 | 8_1 | 0.012538708 | decreased | 1.661838638985569 | 37001_at | 114230 | ENSG00000162909 | 350899 | 824 | NM_001748 |  | proteolysis and peptidolysis | calpain activity /// calcium ion binding | intracellular | Integrin-mediated_cell_adhesion_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Integrin-mediated_cell_adhesion_KEGG/Hs_Integrin-mediated_cell_adhesion_KEGG.htm
X83218 | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | ATP5O | 8_1 | 0.002688064 | decreased | 1.955427545164467 | 37029_at | 600828 | ENSG00000159186 | 409140 | 539 | NM_001697 |  | ion transport /// ATP synthesis coupled proton transport /// proton transport | transporter activity /// hydrolase activity /// hydrogen-transporting ATP synthase activity, rotational mechanism /// hydrogen-transporting ATPase activity, rotational mechanism | membrane fraction /// mitochondrion /// proton-transporting ATP synthase complex (sensu [NAME]) /// proton-transporting two-sector ATPase complex | Electron_Transport_Chain /// Oxidative phosphorylation /// ATP synthesis /// Photosynthesis /// [NAME] assembly /// Type III secretion system | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00190+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00193+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00195+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP02040+3.6.3.14 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03070+3.6.3.14
Z56281 | interferon regulatory factor 3 | IRF3 | 10_1 | 0.026974299 | decreased | 1.398105446040203 | 371_at | 603734 | ENSG00000126456 | 75254 | 3661 | NM_001571 |  | transcription /// regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter | transcription factor activity /// RNA polymerase II transcription factor activity /// transcription cofactor activity | nucleus | Apoptosis | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm
AB002359 | phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) | PFAS | 4_3 | 0.035338275 | decreased | 1.5841931863265 | 37143_s_at | 602133 | ENSG00000178921 | 88139 | 5198 | NM_012393 |  | purine nucleotide biosynthesis /// 'de novo' IMP biosynthesis /// glutamine metabolism | phosphoribosylformylglycinamidine synthase activity /// ATP binding /// ligase activity | cytoplasm | Purine metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+6.3.5.3
[NAME] | glutathione S-transferase theta 1 | GSTT1 | 10_1 | 0.044050861 | decreased | 1.002363803039925 | 37222_at | 600436 | ENSG00000184674 | 268573 | 2952 | NM_000853 |  | response to stress | glutathione transferase activity /// transferase activity | --- | Glutathione metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00480+2.5.1.18
U49844 | [NAME] and [NAME] related | ATR | 4_1 | 0.033764662 | decreased | 1.504684154266009 | 37229_at | 210600 /// 601215 | ENSG00000175054 | 271791 | 545 | NM_001184 |  | cell cycle checkpoint /// DNA repair /// cell cycle /// development | DNA binding /// protein serine/threonine kinase activity /// binding /// transferase activity /// manganese ion binding | nucleus /// chromosome | --- | ---
U79260 | fatso | FTO | 10_1 | 0.026153562 | decreased | 1.350668829921922 | 37242_at | --- | ENSG00000140718 | 528833 | 79068 | XM_051200 |  | --- | --- | --- | --- | ---
AF016004 | glycoprotein M6B | GPM6B | 10_1 | 0.016724391 | decreased | 1.897882410994636 | 37251_s_at | 300051 | ENSG00000046653 | 495710 | 2824 | NM_001001994 /// NM_001001995 /// NM_001001996 /// NM_005278 |  | neurogenesis /// cell differentiation | --- | integral to membrane | --- | ---
AI829890 | prune homolog (Drosophila) | PRUNE | 7_1 | 0.041992219 | decreased | 1.473738159806735 | 37256_at | --- | ENSG00000143363 | 78524 | 58497 | NM_021222 |  | --- | pyrophosphatase activity | cytoplasm | --- | ---
U51903 | IQ motif containing GTPase activating protein 2 | IQGAP2 | 10_1 | 0.00702493 | decreased | 2.026334645485568 | 37276_at | 605401 | ENSG00000145703 | 291030 | 10788 | NM_006633 |  | signal transduction /// small GTPase mediated signal transduction | [NAME] binding /// GTPase inhibitor activity /// Ras GTPase activator activity /// calmodulin binding | [NAME] | G13_Signaling_Pathway | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G13_Signaling_Pathway/Hs_G13_Signaling_Pathway.htm
U35451 | chromobox homolog 1 (HP1 beta homolog Drosophila ) | [NAME] | 7_1 | 0.007164702 | decreased | 2.203980915400277 | 37304_at | 604511 | ENSG00000108468 | 77254 | 10951 | NM_006807 |  | chromatin assembly or disassembly | chromatin binding | chromosome, pericentric region /// chromatin /// nucleoplasm /// nuclear heterochromatin | --- | ---
AI057607 | chromosome 14 open reading frame 11 | C14orf11 | 2_1 | 0.041441207 | decreased | 1.67038914270287 | 37315_f_at | --- | ENSG00000129518 | 433269 | 55837 | NM_018453 |  | --- | --- | --- | --- | ---
D14697 | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | FDPS | 7_1 | 0.041373674 | decreased | 2.561903617202955 | 37325_at | 134629 | ENSG00000160752 | 335918 | 2224 | NM_002004 |  | cholesterol biosynthesis /// isoprenoid biosynthesis | geranyltranstransferase activity /// transferase activity | --- | Cholesterol_Biosynthesis /// Biosynthesis of steroids /// Terpenoid biosynthesis | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00100+2.5.1.10 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00900+2.5.1.10
AF053070 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | NDUFV1 | 2_1 | 0.047914104 | decreased | 1.163392538141311 | 37329_at | 161015 /// 203450 /// 252010 /// 256000 | ENSG00000167792 | 7744 | 4723 | NM_007103 |  | electron transport /// mitochondrial electron transport, NADH to ubiquinone | NADH dehydrogenase activity /// iron ion binding /// NADH dehydrogenase (ubiquinone) activity /// FMN binding /// NAD binding | membrane fraction /// mitochondrion /// mitochondrial inner membrane | Electron_Transport_Chain /// Oxidative phosphorylation | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00190+1.6.99.3
AA845349 | high mobility group nucleosomal binding domain 3 | HMGN3 | 7_1 | 0.028910941 | decreased | 1.910751626530973 | 37348_s_at | 604502 | ENSG00000118418 | 77558 | 9324 | NM_004242 /// NM_138730 |  | --- | DNA binding /// thyroid hormone receptor binding | chromatin /// nucleus /// nucleus | --- | ---
AL031177 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | PSMD10 | 9_1 | 0.024568701 | decreased | 1.47106387393834 | 37350_at | 603480 | ENSG00000101843 | 522752 | 5716 | NM_002814 /// NM_170750 |  | --- | --- | cytosol /// proteasome regulatory particle (sensu [NAME]) | Proteasome_Degradation | [NAME]
D00723 | glycine cleavage system protein H (aminomethyl carrier) | GCSH | 7_1 | 0.045618722 | decreased | 1.577146412072529 | 37357_at | 238330 /// 605899 | ENSG00000140905 /// ENSG00000187615 | 546256 | 2653 | NM_004483 |  | glycine catabolism | aminomethyltransferase activity | mitochondrion /// glycine cleavage complex | --- | ---
AA292277 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | NFATC4 | 1_10 | 0.044059202 | increased | 1.414381738313244 | 37368_at | 602699 | ENSG00000100968 | 77810 | 4776 | NM_004554 |  | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// inflammatory response | transcription factor activity /// transcription coactivator activity | nucleus | --- | ---
M81780 | sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) | SMPD1 | 1_10 | 0.003502381 | increased | 1.932692603877227 | 37372_at | 257200 /// 607608 /// 607616 | ENSG00000166311 | 498173 | 6609 | NM_000543 /// NM_001007593 |  | carbohydrate metabolism /// sphingomyelin catabolism /// signal transduction /// neurogenesis | sphingomyelin phosphodiesterase activity /// hydrolase activity, acting on glycosyl bonds | lysosome | Ovarian_Infertility_Genes /// Glycosphingolipid metabolism | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Ovarian_Infertility_Genes/Hs_Ovarian_Infertility_Genes.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00600+3.1.4.12
M68864 | ORF | LOC51035 | 10_1 | 0.04267601 | decreased | 1.932109272280726 | 37376_at | --- | ENSG00000162191 | 351296 | 51035 | NM_015853 |  | --- | --- | --- | --- | ---
[NAME] | POU domain, class 2, transcription factor 2 | POU2F2 | 1_10 | 0.037243636 | increased | 1.639563927810054 | 37418_at | 164176 | ENSG00000028277 | 515429 | 5452 | NM_002698 |  | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// humoral immune response | DNA binding /// transcription factor activity | nucleus /// nucleus | --- | ---
U30246 | solute carrier family 12 (sodium/potassium/chloride transporters), member 2 | SLC12A2 | 9_1 | 0.049606215 | decreased | 2.50747922465353 | 37423_at | 600840 | ENSG00000064651 | 162585 | 6558 | NM_001046 |  | ion transport /// potassium ion transport /// sodium ion transport /// chloride transport /// amino acid transport | transporter activity /// amino acid-polyamine transporter activity /// sodium:potassium:chloride symporter activity /// symporter activity | membrane fraction /// integral to plasma membrane /// membrane | --- | ---
Y07593 | [NAME] and adenovirus receptor | CXADR | 7_1 | 0.037204897 | decreased | 1.457723155138593 | 37534_at | 602621 | ENSG00000154639 | 473417 | 1525 | NM_001338 |  | --- | receptor activity /// receptor activity | plasma membrane /// integral to plasma membrane | --- | ---
L04510 | tripartite motif-containing 23 | TRIM23 | 9_1 | 0.022330607 | decreased | 2.104435341247284 | 37537_at | 601747 | ENSG00000113595 | 792 | 373 | NM_001656 /// NM_033227 /// NM_033228 |  | small GTPase mediated signal transduction /// protein ubiquitination | GTPase activity /// ubiquitin-protein ligase activity /// GTP binding /// enzyme activator activity /// zinc ion binding | ubiquitin ligase complex | --- | ---
D25304 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | ARHGEF6 | 10_1 | 0.029529037 | decreased | 1.80765332734027 | 37543_at | 300267 /// 300436 | ENSG00000129675 | 522795 | 9459 | NM_004840 |  | apoptosis /// JNK cascade | Rho guanyl-nucleotide exchange factor activity /// GTPase activator activity | intracellular | --- | ---
D31764 | sorting nexin 17 | SNX17 | 9_1 | 0.043414438 | decreased | 2.061200877589637 | 37654_at | 605963 | ENSG00000115234 | 278569 | 9784 | NM_014748 |  | intracellular protein transport /// intracellular signaling cascade /// endosome transport /// regulation of endocytosis /// low-density lipoprotein catabolism | receptor binding /// protein C-terminus binding | early endosome /// membrane | --- | ---
AF104421 | uroporphyrinogen decarboxylase | UROD | 8_3 | 0.029729994 | decreased | 1.720293270536809 | 37667_at | 176100 | ENSG00000126088 | 78601 | 7389 | NM_000374 |  | heme biosynthesis | uroporphyrinogen decarboxylase activity /// lyase activity | --- | Heme_Biosynthesis /// [NAME] and chlorophyll metabolism | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00860+4.1.1.37
J04543 | annexin A7 | ANXA7 | 7_1 | 0.028060844 | decreased | 1.633257661845543 | 37670_at | 186360 | ENSG00000138279 | 386434 | 310 | NM_001156 /// NM_004034 |  | negative regulation of coagulation | voltage-gated calcium channel activity /// calcium ion binding /// calcium-dependent phospholipid binding | --- | --- | ---
M81118 | alcohol dehydrogenase 5 (class III), chi polypeptide | ADH5 | 9_1 | 0.007688671 | decreased | 1.463639396629152 | 37707_i_at | 103710 | ENSG00000197894 | 78989 | 128 | NM_000671 |  | ethanol oxidation | alcohol dehydrogenase activity /// formaldehyde dehydrogenase (glutathione) activity /// electron transporter activity /// fatty acid binding /// zinc ion binding /// oxidoreductase activity | --- | Pyruvate metabolism /// Methane metabolism | [NAME] /// [NAME]
U26266 | deoxyhypusine synthase | DHPS | 4_3 | 0.041269625 | decreased | 1.489499038226676 | 37722_s_at | 600944 | ENSG00000095059 | 79064 | 1725 | NM_001930 /// NM_013406 /// NM_013407 |  | protein biosynthesis /// positive regulation of cell proliferation /// hypusine biosynthesis from peptidyl-lysine /// spermidine catabolism to deoxyhypusine, using deoxyhypusine synthase | transferase activity | --- | --- | ---
M34423 | galactosidase, beta 1 | [NAME] | 10_1 | 0.042726421 | decreased | 1.448265638484868 | 37742_at | 230500 | ENSG00000170266 | 443031 | 2720 | NM_000404 |  | carbohydrate metabolism | beta-galactosidase activity /// hydrolase activity, acting on glycosyl bonds | lysosome /// beta-galactosidase complex | Galactose metabolism /// N-Glycan degradation /// Glycosaminoglycan degradation /// Glycerolipid metabolism /// Glycosphingolipid metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00052+3.2.1.23 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00511+3.2.1.23 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00531+3.2.1.23 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00561+3.2.1.23 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00600+3.2.1.23
U41813 | homeo box A9 | HOXA9 | 2_4 | 0.036567715 | decreased | 1.933741597770882 | 37809_at | 142956 | ENSG00000078399 | 127428 | 3205 | NM_002142 /// NM_152739 |  | transcription /// regulation of transcription, DNA-dependent /// development | transcription factor activity /// transcriptional activator activity | nucleus /// nucleus | --- | ---
U82759 | homeo box A9 | HOXA9 | 5_7 | 0.04288683 | increased | 1.958521260226747 | 37810_at | 142956 | ENSG00000078399 | 127428 | 3205 | NM_002142 /// NM_152739 |  | transcription /// regulation of transcription, DNA-dependent /// development | transcription factor activity /// transcriptional activator activity | nucleus /// nucleus | --- | ---
AF055019 | Homeodomain interacting protein kinase 2 | HIPK2 | 6_1 | 0.04055257 | decreased | 1.537943359021054 | 37851_at | 606868 | ENSG00000064393 | 397465 | 28996 | NM_022740 |  | regulation of cell cycle /// transcription /// regulation of transcription, DNA-dependent /// protein amino acid phosphorylation /// apoptosis /// induction of apoptosis by intracellular signals /// virus-host interaction /// positive regulation of transforming growth factor beta receptor signaling pathway /// positive regulation of JNK cascade | transcription corepressor activity /// protein serine/threonine kinase activity /// protein binding /// ATP binding /// transferase activity /// virion binding | nucleus /// cytoplasm /// nuclear body | --- | ---
AF057036 | collagen-like tail subunit (single strand of homotrimer) of [NAME] | COLQ | 5_10 | 0.049303346 | increased | 1.304277420080384 | 37858_at | 603033 /// 603034 | --- | 146735 | 8292 | NM_005677 /// NM_080538 /// NM_080539 /// NM_080540 /// NM_080541 /// NM_080542 /// NM_080543 /// NM_080544 |  | acetylcholine catabolism in synaptic cleft /// phosphate transport /// asymmetric protein localization /// neurotransmitter catabolism | --- | basal lamina /// extracellular space /// cytoplasm /// synapse | --- | ---
AL080078 | [NAME] 30B | TMEM30B | 7_1 | 0.051357978 | decreased | 1.650408982165553 | 37934_at | --- | ENSG00000182107 | 146180 | 161291 | XM_090844 |  | --- | --- | --- | --- | ---
X53742 | fibulin 1 | FBLN1 | 5_10 | 0.022363576 | increased | 2.303736303045287 | 38027_at | 135820 /// 608180 | ENSG00000077942 | 24601 | 2192 | NM_001996 /// NM_006485 /// NM_006486 /// NM_006487 |  | chitin metabolism /// development | receptor activity /// extracellular matrix structural constituent /// calcium ion binding /// chitin binding | extracellular region /// extracellular matrix (sensu Metazoa) /// extracellular matrix (sensu Metazoa) /// extracellular space /// soluble fraction | --- | ---
D86957 | septin 8 | 2005-09-08 00:00:00 | 7_1 | 0.036007414 | decreased | 1.464208819656136 | 38067_at | 608418 | [NAME] | 533017 | 23176 | XM_034872 |  | cell cycle | GTP binding | --- | --- | ---
AL049386 | Notch homolog 2 (Drosophila) | NOTCH2 | 10_1 | 0.006864429 | decreased | 1.611579586737326 | 38083_at | 600275 | ENSG00000134250 | 549056 | 4853 | NM_024408 |  | cell fate determination /// transcription /// regulation of transcription, DNA-dependent /// anti-apoptosis /// induction of apoptosis /// cell cycle arrest /// Notch signaling pathway /// neurogenesis /// negative regulation of cell proliferation /// cell growth /// stem cell maintenance /// hemopoiesis /// cell differentiation /// positive regulation of [NAME] protein signal transduction /// regulation of development | ligand-regulated transcription factor activity /// receptor activity /// calcium ion binding /// protein binding /// protein heterodimerization activity | nucleus /// integral to plasma membrane /// cell surface /// membrane | --- | ---
D38555 | SEC24 related gene family, member C (S. cerevisiae) | SEC24C | 4_3 | 0.01108026 | decreased | 1.449550279220613 | 38117_at | 607185 | ENSG00000176986 | 81964 | 9632 | NM_004922 /// NM_198597 |  | intracellular protein transport /// ER to Golgi transport | [NAME] binding /// protein binding | endoplasmic reticulum /// Golgi apparatus /// COPII vesicle coat | --- | ---
U31248 | zinc finger protein 174 | ZNF174 | 10_1 | 0.022466271 | decreased | 1.28876030864987 | 38179_at | 603900 | ENSG00000103343 | 155204 | 7727 | [NAME] |  | negative regulation of transcription from RNA polymerase II promoter /// transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// protein binding /// zinc ion binding | nucleus | --- | ---
D90041 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | NAT1 | 6_1 | 0.023283685 | decreased | 1.348630827190623 | 38187_at | 108345 | ENSG00000171428 | 155956 | 9 | NM_000662 |  | metabolism | arylamine N-acetyltransferase activity /// acetyltransferase activity /// transferase activity | --- | --- | ---
AB014545 | DEP domain containing 5 | DEPDC5 | 10_1 | 0.04877857 | decreased | 1.870270464634761 | 38189_s_at | --- | ENSG00000100150 | 435022 | 9681 | NM_001007188 /// NM_014662 |  | intracellular signaling cascade | --- | --- | --- | ---
AB014543 | clusterin associated protein 1 | CLUAP1 | 10_1 | 0.042148989 | decreased | 1.815224631899036 | 38192_at | --- | ENSG00000103351 | 155995 | 23059 | NM_015041 /// NM_024793 |  | --- | --- | --- | --- | ---
AB006909 | microphthalmia-associated transcription factor | MITF | 9_1 | 0.050152732 | decreased | 1.424876988711148 | 38228_g_at | 103470 /// 103500 /// 156845 /// 193510 | ENSG00000187098 | 166017 | 4286 | NM_000248 /// NM_006722 /// NM_198158 /// NM_198159 /// NM_198177 /// NM_198178 |  | transcription /// regulation of transcription, DNA-dependent /// development /// perception of sound /// melanocyte differentiation | DNA binding /// transcriptional activator activity /// transcriptional activator activity | nucleus | --- | ---
X90579 | cytochrome P450, family 3, subfamily A, polypeptide 5 | CYP3A5 | 1_8 | 0.031167884 | increased | 2.160686314381786 | 38229_at | 145500 /// 605325 | ENSG00000106258 | 150276 | 1577 | /// NM_000777 |  | electron transport /// xenobiotic metabolism /// transport /// steroid metabolism | monooxygenase activity /// oxygen binding /// unspecific monooxygenase activity | membrane fraction /// endoplasmic reticulum /// microsome /// membrane | Irinotecan_pathway_PharmGKB /// Fatty acid metabolism /// gamma-Hexachlorocyclohexane degradation /// Tryptophan metabolism | www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Irinotecan_pathway_PharmGKB/Hs_Irinotecan_pathway_PharmGKB.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00071+1.14.14.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00361+1.14.14.1 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+1.14.14.1
AI097085 | --- | --- | 1_10 | 0.035722141 | increased | 1.570327112487812 | 38245_i_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AB011124 | ProSAPiP1 protein | ProSAPiP1 | 8_3 | 0.041330925 | decreased | 1.546186590493525 | 38248_at | --- | ENSG00000088899 | 90232 | 9762 | NM_014731 |  | --- | --- | cytoplasm /// membrane | --- | ---
Y11731 | 8-oxoguanine DNA glycosylase | OGG1 | 6_1 | 0.027051325 | decreased | 1.896611514839214 | 38334_g_at | 144700 /// 601982 | ENSG00000114026 | 380271 | 4968 | NM_002542 /// NM_016819 /// NM_016820 /// NM_016821 /// NM_016826 /// NM_016827 /// NM_016828 /// NM_016829 |  | carbohydrate metabolism /// base-excision repair /// base-excision repair | DNA binding /// damaged DNA binding /// endonuclease activity /// purine-specific oxidized base lesion DNA N-glycosylase activity /// purine-specific oxidized base lesion DNA N-glycosylase activity /// purine-specific oxidized base lesion DNA N-glycosylase activity /// hydrolase activity, acting on glycosyl bonds /// lyase activity | nucleus /// nucleoplasm /// mitochondrion | --- | ---
AF042378 | tubulin, gamma complex associated protein 3 | TUBGCP3 | 8_1 | 0.033012255 | decreased | 1.632561444814533 | 38353_at | --- | ENSG00000126216 | 224152 | 10426 | NM_006322 |  | microtubule nucleation /// mitosis | structural constituent of cytoskeleton /// gamma-tubulin binding | centriole /// polar microtubule | --- | ---
M19481 | follistatin | FST | 5_10 | 0.017533549 | increased | 1.696053860938286 | 38356_at | 136470 /// 184700 | ENSG00000134363 | 9914 | 10468 | NM_006350 /// NM_013409 |  | development /// negative regulation of follicle-stimulating hormone secretion | activin inhibitor activity | extracellular region | TGF_Beta_Signaling_Pathway | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_TGF_Beta_Signaling_Pathway/Hs_TGF_Beta_Signaling_Pathway.htm
AF026086 | peroxisome biogenesis factor 1 | PEX1 | 4_1 | 0.010702375 | decreased | 2.407194226852433 | 38365_at | 202370 /// 214100 /// 266510 /// 602136 | ENSG00000127980 | 164682 | 5189 | [NAME] |  | peroxisome organization and biogenesis /// protein transport | nucleotide binding /// ATP binding /// nucleoside-triphosphatase activity /// ATPase activity, coupled | peroxisome /// membrane | --- | ---
AF112219 | esterase D/formylglutathione hydrolase | ESD | 9_1 | 0.04926173 | decreased | 1.866731154837928 | 38375_at | 133280 | ENSG00000139684 | 432491 | 2098 | [NAME] |  | --- | catalytic activity /// serine esterase activity /// hydrolase activity | cytoplasmic vesicle | Alkaloid biosynthesis II | www.genome.ad.jp/dbget-bin/show_pathway?MAP00960+3.1.1.1
X87843 | menage a trois 1 (CAK assembly factor) | MNAT1 | 10_1 | 0.041189792 | decreased | 1.887175146802207 | 38387_at | 602659 | ENSG00000020426 | 509523 | 4331 | NM_002431 |  | regulation of cyclin dependent protein kinase activity /// DNA repair /// transcription /// regulation of transcription from RNA polymerase II promoter /// protein complex assembly /// cell cycle /// cell proliferation /// protein ubiquitination | ubiquitin-protein ligase activity /// zinc ion binding | ubiquitin ligase complex /// nucleus | G1_to_S_cell_cycle_Reactome /// RNA_transcription_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G1_to_S_cell_cycle_Reactome/Hs_G1_to_S_cell_cycle_Reactome.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_RNA_transcription_Reactome/Hs_RNA_transcription_Reactome.htm
AI920820 | family with sequence similarity 61, member A | FAM61A | 6_1 | 0.048464674 | decreased | 1.489916827695859 | 38400_at | --- | ENSG00000105216 | 407368 | 26065 | NM_015578 |  | --- | --- | --- | --- | ---
X72964 | centrin, EF-hand protein, 2 | CETN2 | 8_3 | 0.039910968 | decreased | 2.269333820176957 | 38410_at | 300006 | ENSG00000147400 | 82794 | 1069 | NM_004344 |  | cytokinesis /// cell cycle /// mitosis | calcium ion binding | centrosome | --- | ---
AA015605 | armadillo repeat containing, X-linked 6 | ARMCX6 | 8_1 | 0.017964919 | decreased | 1.46891348048142 | 38440_s_at | --- | ENSG00000198960 | 83530 | 54470 | NM_001009584 /// NM_019007 |  | --- | --- | --- | --- | ---
U65676 | Hermansky-Pudlak syndrome 1 | HPS1 | 1_10 | 0.03420222 | increased | 1.709423305755592 | 38468_at | 203300 /// 604982 | ENSG00000107521 | 404568 | 3257 | NM_000195 /// NM_182637 /// NM_182638 /// NM_182639 |  | --- | --- | --- | --- | ---
AA760866 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | NDUFC1 | 9_1 | 0.024009094 | decreased | 2.035245922062789 | 38485_at | 603844 | ENSG00000109390 | 84549 | 4717 | NM_002494 |  | mitochondrial electron transport, NADH to ubiquinone | NADH dehydrogenase activity /// NADH dehydrogenase (ubiquinone) activity /// oxidoreductase activity | mitochondrion | Electron_Transport_Chain | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm
AF031167 | interleukin 15 | IL15 | 7_4 | 0.018245838 | decreased | 1.437241306546551 | 38488_s_at | 600554 | ENSG00000164136 | 311958 | 3600 | NM_000585 /// NM_172174 /// NM_172175 |  | immune response /// signal transduction /// cell-cell signaling /// positive regulation of cell proliferation | signal transducer activity /// hematopoietin/interferon-class (D200-domain) cytokine receptor binding | extracellular space /// membrane fraction /// endosome /// Golgi apparatus /// integral to plasma membrane | --- | ---
U00944 | chromosome X open reading frame 45 | CXorf45 | 6_1 | 0.003103135 | decreased | 1.613805036271577 | 38490_r_at | --- | ENSG00000101901 | 443061 | 79868 | NM_024810 |  | --- | --- | --- | --- | ---
AA428150 | hypothetical protein FLJ22709 | FLJ22709 | 8_1 | 0.040313315 | decreased | 2.36171796062912 | 38531_at | --- | ENSG00000099330 | 422676 | 79629 | NM_024578 |  | --- | --- | --- | --- | ---
M18079 | fatty acid binding protein 2, intestinal | FABP2 | 4_3 | 0.025383004 | decreased | 1.234055970358083 | 38587_at | 134640 | ENSG00000145384 | 282265 | 2169 | NM_000134 |  | fatty acid metabolism /// transport /// digestion | lipid transporter activity /// fatty acid binding | --- | --- | ---
AB006622 | --- | --- | 5_10 | 0.026256337 | increased | 1.314992882306289 | 38595_r_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AB009285 | craniofacial development protein 1 | CFDP1 | 7_1 | 0.017134076 | decreased | 1.484755888183687 | 38664_at | 608108 | ENSG00000153774 | 461361 | 10428 | NM_006324 |  | --- | --- | --- | --- | ---
AF020351 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | NDUFS4 | 8_1 | 0.045367498 | decreased | -20.92041182678585 | 38695_at | 252010 /// 256000 /// 602694 | ENSG00000164258 | 528222 | 4724 | [NAME] |  | electron transport /// mitochondrial electron transport, NADH to ubiquinone | NADH dehydrogenase activity /// NADH dehydrogenase (ubiquinone) activity | membrane fraction /// mitochondrion | Electron_Transport_Chain | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm
AL050159 | DKFZP586A0522 protein | DKFZP586A0522 | 9_1 | 0.028461167 | decreased | 7.343203001381955 | 38717_at | --- | ENSG00000185432 | 288771 | 25840 | NM_014033 |  | --- | S-adenosylmethionine-dependent methyltransferase activity /// transferase activity | --- | --- | ---
X91788 | chloride channel, nucleotide-sensitive, 1A /// chromosome 3 open reading frame 4 | CLNS1A /// C3orf4 | 7_1 | 0.002241295 | decreased | 1.454822593804399 | 38732_at | 602158 | ENSG00000074201 /// ENSG00000080822 | 107393 | 1207 /// 56650 | NM_001293 /// NM_019895 |  | transport /// chloride transport /// regulation of cell volume /// visual perception /// circulation | auxiliary transport protein activity | nucleus /// plasma membrane /// membrane /// integral to membrane | --- | ---
[NAME] | lipase A, lysosomal acid, cholesterol esterase ([NAME] disease) | LIPA | 10_1 | 0.014000404 | decreased | 1.90967081893687 | 38745_at | 278000 | ENSG00000107798 | 127445 | 3988 | NM_000235 |  | N-linked glycosylation /// lipid catabolism | [NAME] activity /// sterol esterase activity /// hydrolase activity /// carboxylic ester hydrolase activity | lysosome | --- | ---
X84709 | Fas (TNFRSF6)-associated via death domain | FADD | 6_1 | 0.041890139 | decreased | 4.675186338694748 | 38755_at | 602457 | ENSG00000168040 | 86131 | 8772 | NM_003824 |  | cell surface receptor linked signal transduction /// induction of apoptosis via death domain receptors /// antimicrobial humoral response (sensu Vertebrata) /// regulation of apoptosis /// positive regulation of I-kappaB kinase/NF-kappaB cascade | signal transducer activity /// death receptor binding /// protein binding | cytoplasm | Apoptosis /// Apoptosis_GenMAPP /// Apoptosis_KEGG | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis/Hs_Apoptosis.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_GenMAPP/Hs_Apoptosis_GenMAPP.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Apoptosis_KEGG/Hs_Apoptosis_KEGG.htm
X13916 | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | LRP1 | 4_3 | 0.012118362 | decreased | 1.802604796308571 | 38775_at | 107770 | ENSG00000123384 | 162757 | 4035 | NM_002332 |  | lipid metabolism /// endocytosis /// cell proliferation | receptor activity /// lipid transporter activity /// calcium ion binding /// calcium ion binding /// lipoprotein binding | membrane fraction /// integral to plasma membrane /// coated pit /// membrane | Statin_Pathway_PharmGKB | [NAME]
X69908 | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9), isoform 2 | ATP5G2 | 10_1 | 0.038726474 | decreased | 1.663384324670037 | 38777_at | 603193 | ENSG00000135390 | 524464 | 517 | NM_001002031 /// NM_005176 |  | ion transport /// ATP synthesis coupled proton transport /// proton transport | transporter activity /// lipid binding /// hydrogen-transporting ATP synthase activity, rotational mechanism /// hydrogen-transporting ATPase activity, rotational mechanism | membrane fraction /// mitochondrion /// proton-transporting ATP synthase complex (sensu [NAME]) /// membrane /// proton-transporting two-sector ATPase complex | Electron_Transport_Chain /// Purine metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00230+3.6.1.14
M16594 | glutathione S-transferase A1 /// glutathione S-transferase A2 | GSTA1 /// GSTA2 | 10_1 | 0.045849211 | decreased | 1.630931340269093 | 38781_at | 138359 /// 138360 | ENSG00000187919 /// ENSG00000096087 | 94107 | 2938 /// 2939 | NM_000846 /// NM_145740 |  | metabolism /// metabolism | glutathione transferase activity /// transferase activity /// glutathione transferase activity /// glutathione transferase activity | cytoplasm | Glutathione metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00480+2.5.1.18
L25879 | epoxide hydrolase 1, microsomal (xenobiotic) | EPHX1 | 10_1 | 0.002367241 | decreased | 1.671166073208287 | 38790_at | 132810 | ENSG00000143819 | 89649 | 2052 | NM_000120 |  | xenobiotic metabolism /// response to toxin /// aromatic compound catabolism | epoxide hydrolase activity /// hydrolase activity | endoplasmic reticulum /// microsome /// membrane /// integral to membrane | Tetrachloroethene degradation | www.genome.ad.jp/dbget-bin/show_pathway?MAP00625+3.3.2.3
U66685 | ATP-binding cassette, sub-family F (GCN20), member 3 | ABCF3 | 2_1 | 0.018424055 | decreased | 1.255586316007995 | 38830_at | --- | ENSG00000161204 | 361323 | 55324 | NM_018358 |  | --- | --- | --- | --- | ---
AF068195 | ubiquitin associated domain containing 1 | UBADC1 | 8_1 | 0.03695581 | decreased | 1.69111544181604 | 38841_at | 608129 | ENSG00000130560 | 9194 | 10422 | NM_016172 |  | --- | --- | nucleus | --- | ---
W26851 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein | NFATC2IP | 10_1 | 0.026006327 | decreased | 1.946594827308602 | 38864_at | --- | ENSG00000176953 | 513470 | 84901 | NM_032815 |  | protein modification | --- | --- | --- | ---
AF007748 | transportin 2 (importin 3, karyopherin beta 2b) | [NAME] | 4_3 | 0.050977996 | decreased | 1.290008956389216 | 38896_at | 603002 | ENSG00000105576 | 416049 | 30000 | NM_013433 |  | protein-nucleus import, docking /// protein transport | nuclear localization sequence binding /// protein transporter activity | nucleus /// nucleus /// nuclear pore /// cytoplasm /// cytoplasm | --- | ---
U95822 | mitofusin 1 | MFN1 | 5_10 | 0.034210958 | increased | 1.355458039553217 | 38899_s_at | 608506 | ENSG00000171109 | 478383 | 55669 | NM_017927 /// NM_033540 |  | mitochondrial fusion | GTPase activity /// GTP binding /// hydrolase activity | mitochondrion /// mitochondrial outer membrane /// integral to membrane | --- | ---
X96924 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | SLC25A1 | 7_1 | 0.046639664 | decreased | 1.288918496002851 | 38998_g_at | 190315 | ENSG00000100075 | 111024 | 6576 | NM_005984 |  | transport /// mitochondrial citrate transport | transporter activity /// binding /// citrate transporter activity | mitochondrion /// mitochondrial inner membrane /// integral to membrane | Fatty_Acid_Synthesis | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Fatty_Acid_Synthesis/Hs_Fatty_Acid_Synthesis.htm
AF047470 | malate dehydrogenase 2, NAD (mitochondrial) | MDH2 | 7_1 | 0.032748499 | decreased | 2.066175988472634 | 39001_at | 154100 | ENSG00000146701 | 520967 | 4191 | NM_005918 |  | glycolysis /// tricarboxylic acid cycle /// malate metabolism | L-lactate dehydrogenase activity /// oxidoreductase activity /// L-malate dehydrogenase activity | mitochondrial matrix | Glycolysis_and_Gluconeogenesis /// Krebs-TCA_Cycle /// Citrate cycle (TCA cycle) /// Pyruvate metabolism /// Glyoxylate and dicarboxylate metabolism /// Carbon fixation /// Reductive carboxylate cycle (CO2 fixation) | [NAME] /// www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Krebs-TCA_Cycle/Hs_Krebs-TCA_Cycle.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00020+1.1.1.37 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00620+1.1.1.37 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00630+1.1.1.37 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00710+1.1.1.37 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00720+1.1.1.37
Z78368 | chromosome 1 open reading frame 8 | C1orf8 | 7_1 | 0.041862295 | decreased | 1.534031190633574 | 39033_at | --- | ENSG00000116209 | 523262 | 9528 | NM_004872 |  | --- | --- | integral to membrane | --- | ---
W26655 | adiponectin receptor 2 | ADIPOR2 | 6_1 | 0.038035123 | decreased | 1.355938035529676 | 39045_at | 607946 | ENSG00000006831 | 371642 | 79602 | NM_024551 |  | lipid metabolism /// hormone-mediated signaling /// fatty acid oxidation | receptor activity /// hormone binding | integral to membrane | --- | ---
U01147 | active BCR-related gene | ABR | 3_2 | 0.024039066 | decreased | 1.205788950466593 | 39058_at | 600365 | ENSG00000159842 | 159306 | 29 | NM_001092 /// NM_021962 |  | small GTPase mediated signal transduction | guanyl-nucleotide exchange factor activity /// GTPase activator activity | --- | --- | ---
D28137 | bone marrow stromal cell antigen 2 | BST2 | 6_1 | 0.046627763 | decreased | 1.153403244270813 | 39061_at | 600534 | ENSG00000130303 | 118110 | 684 | NM_004335 |  | humoral immune response /// cell-cell signaling /// development /// cell proliferation /// positive regulation of I-kappaB kinase/NF-kappaB cascade | signal transducer activity | integral to plasma membrane | --- | ---
D83327 | tetratricopeptide repeat domain 3 | TTC3 | 7_1 | 0.029423434 | decreased | 3.110933073245976 | 39065_s_at | 602259 | ENSG00000182670 | 368214 | 7267 | NM_001001894 /// NM_003316 |  | protein ubiquitination | ubiquitin-protein ligase activity /// binding /// zinc ion binding | ubiquitin ligase complex | --- | ---
AI262789 | protein disulfide isomerase-associated 4 | PDIA4 | 10_1 | 0.019916499 | decreased | 2.368285886612513 | 39113_at | --- | ENSG00000155660 | 93659 | 9601 | NM_004911 |  | electron transport /// protein secretion | protein disulfide isomerase activity /// electron transporter activity /// isomerase activity | endoplasmic reticulum lumen | --- | ---
U31110 | transient receptor potential cation channel, subfamily C, member 1 | TRPC1 | 10_1 | 0.043227213 | decreased | 1.99516502223205 | 39123_s_at | 602343 | ENSG00000144935 | 250687 | 7220 | NM_003304 |  | cation transport /// calcium ion transport | store-operated calcium channel activity | plasma membrane /// integral to plasma membrane | --- | ---
N36842 | [NAME] regulator of nonsense transcripts homolog A (yeast) | UPF3A | 2_1 | 0.033495001 | decreased | 1.725866170249601 | 39131_at | 605530 | ENSG00000169062 | 514737 | 65110 | NM_023011 /// NM_080687 |  | mRNA catabolism, nonsense-mediated decay /// mRNA processing /// mRNA-nucleus export /// transport | nucleotide binding /// [NAME] binding /// nucleocytoplasmic transporter activity | nucleus /// cytoplasm | --- | ---
U47101 | NifU-like N-terminal domain containing | NIFUN | 9_1 | 0.015361914 | decreased | 1.323904880751236 | 39165_at | --- | ENSG00000136003 | 350702 | 23479 | NM_014301 /// NM_213595 |  | nitrogen fixation /// iron-sulfur cluster assembly | iron ion binding | nucleus /// mitochondrion | --- | ---
U43784 | mitogen-activated protein kinase-activated protein kinase 3 | MAPKAPK3 | 4_3 | 0.035405426 | decreased | 1.236295872490089 | 39237_at | 602130 | ENSG00000114738 | 234521 | 7867 | NM_004635 |  | protein amino acid phosphorylation /// response to stress /// signal transduction | protein serine/threonine kinase activity /// MAP kinase kinase activity /// ATP binding /// transferase activity | nucleus | --- | ---
U94319 | PC4 and SFRS1 interacting protein 1 | PSIP1 | 8_1 | 0.02152044 | decreased | 1.574388504227278 | 39243_s_at | 603620 | ENSG00000164985 | 493516 | 11168 | NM_021144 /// NM_033222 |  | --- | --- | --- | --- | ---
AF049884 | Arg/Abl-interacting protein ArgBP2 | ARGBP2 | 2_1 | 0.032738839 | decreased | 2.141458563286786 | 39295_s_at | --- | ENSG00000154556 | 481342 | 8470 | NM_003603 /// NM_021069 |  | --- | nucleic acid binding /// structural constituent of cytoskeleton /// protein binding /// cytoskeletal adaptor activity /// zinc ion binding /// structural constituent of muscle | nucleus /// nucleus /// nucleus /// cytoskeleton /// actin cytoskeleton /// Z disc | --- | ---
AF035284 | fatty acid desaturase 1 | FADS1 | 5_10 | 0.041136718 | increased | 1.364585628244143 | 39373_at | 606148 | ENSG00000149485 | 503546 | 3992 | NM_013402 |  | fatty acid biosynthesis /// fatty acid desaturation /// fatty acid desaturation /// cell-cell signaling /// phospholipid biosynthesis /// cellular response to starvation /// regulation of transcription /// regulation of cell differentiation /// icosanoid biosynthesis | oxidoreductase activity /// oxidoreductase activity /// oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water | membrane fraction /// microsome /// membrane /// integral to membrane | --- | ---
AB011089 | tripartite motif-containing 2 | TRIM2 | 7_1 | 0.047616447 | decreased | 3.857706785756521 | 39382_at | --- | ENSG00000109654 | 435711 | 23321 | NM_015271 |  | protein ubiquitination | ubiquitin-protein ligase activity /// zinc ion binding /// [NAME] binding | ubiquitin ligase complex /// cytoplasm | --- | ---
AJ002190 | glyceronephosphate O-acyltransferase | GNPAT | 10_1 | 0.051153886 | decreased | 1.084717174753926 | 39392_at | 222765 /// 602744 | ENSG00000116906 | 498028 | 8443 | NM_014236 |  | fatty acid metabolism /// metabolism /// organogenesis | acyltransferase activity /// glycerone-phosphate O-acyltransferase activity /// transferase activity | peroxisome /// membrane | --- | ---
M64497 | nuclear receptor subfamily 2, group F, member 2 | NR2F2 | 9_1 | 0.022220516 | decreased | 1.923699135598575 | 39397_at | 107773 | ENSG00000185551 | 347991 | 7026 | NM_021005 |  | transcription /// regulation of transcription from RNA polymerase II promoter /// lipid metabolism /// signal transduction | transcription factor activity /// ligand-regulated transcription factor activity /// steroid hormone receptor activity /// transcription corepressor activity | nucleus | Nuclear_Receptors | [NAME]
AB023205 | tubulin-specific chaperone d | TBCD | 8_3 | 0.050172241 | decreased | 1.541793999330236 | 39398_s_at | 604649 | ENSG00000141556 | 464391 | 6904 | NM_005993 |  | protein folding /// beta-tubulin folding /// mitotic chromosome condensation | binding /// chaperone binding | microtubule | --- | ---
D87455 | UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) | UTP14C | 8_1 | 0.044655687 | decreased | 1.524551487987478 | 39405_at | 608969 | ENSG00000156697 | 512963 | 9724 | NM_021645 |  | --- | --- | --- | --- | ---
U09825 | tripartite motif-containing 26 | TRIM26 | 9_1 | 0.024641601 | decreased | 3.216468214279824 | 39412_at | 600830 | ENSG00000137313 | 485041 | 7726 | NM_003449 |  | protein ubiquitination | DNA binding /// ubiquitin-protein ligase activity /// protein binding /// zinc ion binding | ubiquitin ligase complex | --- | ---
T79616 | ubiquinol-cytochrome c reductase binding protein | UQCRB | 9_1 | 0.004140235 | decreased | 1.560070409157093 | 39427_at | 191330 | ENSG00000156467 | 131255 | 7381 | NM_006294 |  | electron transport /// oxidative phosphorylation /// mitochondrial electron transport, ubiquinol to cytochrome c /// transport /// aerobic respiration | ubiquinol-cytochrome-c reductase activity /// oxidoreductase activity | mitochondrion /// mitochondrial electron transport chain /// inner membrane | Electron_Transport_Chain /// Oxidative phosphorylation | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00190+1.10.2.2
AF035313 | chromosome 5 open reading frame 15 | C5orf15 | 10_1 | 0.049039581 | decreased | 2.260552969680178 | 39517_at | --- | ENSG00000113583 | 355177 | 56951 | NM_020199 |  | --- | --- | integral to membrane | --- | ---
D49817 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | PFKFB3 | 5_10 | 0.040135914 | increased | 1.10271511154037 | 39522_at | 605319 | ENSG00000170525 | 195471 | 5209 | NM_004566 |  | fructose 2,6-bisphosphate metabolism /// fructose 2,6-bisphosphate metabolism /// metabolism | catalytic activity /// 6-phosphofructo-2-kinase activity /// fructose-2,6-bisphosphate 2-phosphatase activity /// fructose-2,6-bisphosphate 2-phosphatase activity /// ATP binding /// kinase activity /// transferase activity /// hydrolase activity | --- | --- | ---
AJ005890 | chromosome X open reading frame 37 | CXorf37 | 10_1 | 0.028289077 | decreased | 1.714922273650409 | 39587_at | --- | ENSG00000101997 | 26333 | 28952 | NM_014008 |  | --- | --- | --- | --- | ---
U44103 | RAB9A, member RAS oncogene family | RAB9A | 9_1 | 0.013162135 | decreased | 1.551482592060486 | 39628_at | 300284 | ENSG00000123595 | 495704 | 9367 | NM_004251 |  | small GTPase mediated signal transduction /// protein transport | GTPase activity /// GTP binding | Golgi apparatus | --- | ---
M64322 | protein tyrosine phosphatase, non-receptor type 7 | PTPN7 | 5_10 | 0.019417038 | increased | 1.989592315120584 | 39672_at | 176889 | ENSG00000143851 | 402773 | 5778 | NM_002832 /// NM_080588 /// NM_080589 |  | protein amino acid dephosphorylation /// protein amino acid dephosphorylation | protein tyrosine phosphatase activity /// protein tyrosine phosphatase activity /// receptor activity /// hydrolase activity | cytoplasm | --- | ---
N53547 | hypothetical protein MGC5508 | MGC5508 | 4_1 | 0.008071938 | decreased | 1.571607190540788 | 39693_at | --- | ENSG00000110108 | 13662 | 79073 | NM_024092 |  | --- | --- | --- | --- | ---
U30521 | chromosome 5 open reading frame 13 | C5orf13 | 6_1 | 0.048338778 | decreased | 2.413810426191463 | 39710_at | 607332 | ENSG00000134986 | 483067 | 9315 | NM_004772 |  | --- | --- | --- | --- | ---
W28214 | Chromobox homolog 5 (HP1 alpha homolog, Drosophila) | CBX5 | 4_1 | 0.04023992 | decreased | 2.072078770258023 | 39715_at | 604478 | ENSG00000094916 | 349283 | 23468 | NM_012117 |  | chromatin assembly or disassembly | chromatin binding /// protein binding | chromatin /// nuclear membrane /// nuclear heterochromatin | --- | ---
N98607 | mitochondrial ribosomal protein L33 | MRPL33 | 7_1 | 0.031662475 | decreased | 1.031259299787486 | 39718_r_at | --- | ENSG00000163797 | 515879 | 9553 | NM_004891 /// NM_145330 |  | protein biosynthesis | structural constituent of ribosome | intracellular /// ribosome | --- | ---
AF044209 | hypothetical protein LOC149603 | LOC149603 | 6_1 | 0.021270328 | decreased | 1.372931163850579 | 39722_at | --- | --- | 356377 | 149603 | XM_047499 |  | protein ubiquitination | ubiquitin-protein ligase activity /// zinc ion binding | ubiquitin ligase complex | --- | ---
U59863 | TRAF family member-associated NFKB activator | TANK | 10_1 | 0.026451188 | decreased | 1.703091910830047 | 39742_at | 603893 | ENSG00000136560 | 516490 | 10010 | NM_004180 /// NM_133484 |  | signal transduction | protein binding | --- | --- | ---
AF052182 | zinc finger, DHHC domain containing 3 | ZDHHC3 | 8_1 | 0.036222616 | decreased | 1.663461865008617 | 39751_at | --- | ENSG00000163812 | 61430 | 51304 | NM_016598 |  | --- | metal ion binding | Golgi apparatus /// integral to membrane | --- | ---
M36803 | hemopexin | HPX | 3_2 | 0.027296755 | decreased | 2.074147567399823 | 39763_at | 142290 | ENSG00000110169 | 426485 | 3263 | [NAME] |  | transport /// iron ion homeostasis /// heme transport | binding /// heme transporter activity | extracellular space | --- | ---
AB018283 | Rho-related BTB domain containing 1 | RHOBTB1 | 3_2 | 0.001225719 | decreased | 1.696331279773472 | 39771_at | 607351 | ENSG00000072422 | 148670 | 9886 | NM_014836 /// NM_198225 |  | small GTPase mediated signal transduction | protein binding /// GTP binding | --- | --- | ---
M29551 | protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta) | PPP3CB | 10_1 | 0.026152686 | decreased | 1.633396445064471 | 39780_at | 114106 | ENSG00000107758 | 500067 | 5532 | NM_021132 |  | regulation of cell cycle /// transcription, DNA-dependent /// protein amino acid dephosphorylation /// signal transduction | protein serine/threonine phosphatase activity /// calcium ion binding /// calmodulin binding /// hydrolase activity | calcineurin complex | --- | ---
D43947 | KIAA0100 gene product | KIAA0100 | 8_3 | 0.01532333 | decreased | 1.295968214088639 | 39783_at | --- | ENSG00000007202 | 151761 | 9703 | NM_014680 |  | tricarboxylic acid cycle | malate dehydrogenase (acceptor) activity | --- | --- | ---
X72308 | chemokine (C-C motif) ligand 7 | CCL7 | 5_10 | 0.023972721 | increased | 1.309253423318191 | 39802_at | 158106 | ENSG00000108688 | 251526 | 6354 | NM_006273 |  | calcium ion homeostasis /// chemotaxis /// inflammatory response /// signal transduction /// cell-cell signaling /// sensory perception /// antimicrobial humoral response (sensu Vertebrata) | chemokine activity /// heparin binding | extracellular space | --- | ---
[NAME] | mitochondrial ribosomal protein L12 | MRPL12 | 2_5 | 0.048474911 | decreased | 2.117013045961734 | 39812_at | 602375 | ENSG00000183093 | 109059 | 6182 | NM_002949 |  | protein biosynthesis /// protein biosynthesis | RNA binding /// structural constituent of ribosome /// structural constituent of ribosome | intracellular /// mitochondrion /// mitochondrial large ribosomal subunit /// ribosome | --- | ---
AI052724 | dehydrogenase/reductase (SDR family) member 7 | DHRS7 | 7_1 | 0.0486718 | decreased | 1.901981790715653 | 39814_s_at | --- | ENSG00000100612 | 59719 | 51635 | NM_016029 |  | metabolism | oxidoreductase activity | --- | --- | ---
D78134 | cold inducible RNA binding protein | CIRBP | 7_1 | 0.009774973 | decreased | 1.348622261188631 | 39864_at | 602649 | ENSG00000099622 | 501309 | 1153 | NM_001280 |  | response to cold | nucleotide binding /// nucleic acid binding /// RNA binding | nucleus | --- | ---
AI377866 | Testes-specific heterogenous nuclear ribonucleoprotein G-T | HNRNPG-T | 5_10 | 0.002071739 | increased | 1.93244753550876 | 39870_at | 605444 | ENSG00000170748 | 121605 | 27288 | NM_014469 |  | --- | nucleotide binding /// nucleic acid binding | ribonucleoprotein complex | --- | ---
Z98885 | bromodomain containing 1 | [NAME] | 10_1 | 0.036940825 | decreased | 1.561858529374671 | 39894_f_at | 604589 | ENSG00000100425 | 127950 | 23774 | NM_014577 |  | regulation of transcription, DNA-dependent /// cell cycle | DNA binding | nucleus /// nucleus | --- | ---
AI961040 | Tubulin, gamma complex associated protein 2 | TUBGCP2 | 1_10 | 0.01132432 | increased | 2.096336180990726 | 39917_at | --- | ENSG00000130640 | 523370 | 10844 | NM_006659 |  | microtubule cytoskeleton organization and biogenesis /// protein complex assembly /// microtubule nucleation | --- | spindle pole /// microtubule organizing center /// microtubule organizing center /// cytoplasmic microtubule | --- | ---
U03905 | chemokine (C-C motif) receptor 2 | [NAME] | 5_10 | 0.021694251 | increased | 1.143963674518386 | 39937_at | 601267 | ENSG00000188680 /// ENSG00000121807 | 511794 | 1231 | NM_000647 /// NM_000648 |  | chemotaxis /// inflammatory response /// cellular defense response /// signal transduction /// G-protein coupled receptor protein signaling pathway /// negative regulation of adenylate cyclase activity /// positive regulation of cytosolic calcium ion concentration /// JAK-STAT cascade /// antimicrobial humoral response (sensu Vertebrata) | rhodopsin-like receptor activity /// receptor activity /// C-C chemokine receptor activity | soluble fraction /// plasma membrane /// integral to plasma membrane | GPCRDB_Class_A_Rhodopsin-like /// GPCRDB_Other /// Peptide_GPCRs | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Class_A_Rhodopsin-like/Hs_GPCRDB_Class_A_Rhodopsin-like.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_GPCRDB_Other/Hs_GPCRDB_Other.htm /// www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Peptide_GPCRs/Hs_Peptide_GPCRs.htm
Z75311 | RAD50 homolog (S. cerevisiae) | RAD50 | 6_1 | 0.011613564 | decreased | 1.268902566370524 | 39941_at | 604040 | ENSG00000113522 | 242635 | 10111 | NM_005732 /// NM_133482 |  | regulation of mitotic recombination /// double-strand break repair /// telomerase-dependent telomere maintenance /// cell cycle /// meiosis /// meiotic recombination | single-stranded DNA specific endodeoxyribonuclease activity /// endonuclease activity /// ATP binding /// 3'-5' exonuclease activity /// hydrolase activity /// ATPase activity | chromosome, telomeric region /// Mre11 complex | --- | ---
AB011127 | [NAME] and microtubule interacting protein 2 | KIAA0555 | 10_1 | 0.02560884 | decreased | 1.316643464440897 | 39952_at | --- | ENSG00000176049 | 533025 | 9832 | NM_014790 |  | --- | --- | --- | --- | ---
AB019527 | [NAME], down-regulated in cancer 1 | LDOC1 | 8_1 | 0.004025093 | decreased | 2.317403987487956 | 39967_at | 300402 | ENSG00000182195 | 45231 | 23641 | NM_012317 |  | negative regulation of cell proliferation | --- | nucleus | --- | ---
S74720 | nuclear receptor subfamily 0, group B, member 1 | NR0B1 | 10_1 | 0.046495207 | decreased | 0.8759476028415676 | 39970_at | 300018 /// 300200 /// 300473 | ENSG00000169297 | 268490 | 190 | NM_000475 |  | transcription /// regulation of transcription, DNA-dependent /// steroid biosynthesis /// sex determination | transcription factor activity /// steroid hormone receptor activity | nucleus | Nuclear_Receptors | [NAME]
AF061258 | PDZ and LIM domain 5 | PDLIM5 | 7_1 | 0.035592096 | decreased | 1.538389161857983 | 40060_r_at | 605904 | ENSG00000163110 | 480311 | 10611 | NM_001011513 /// NM_001011514 /// NM_001011515 /// NM_001011516 /// NM_006457 |  | heart development | [NAME] binding /// protein kinase C binding /// protein binding /// zinc ion binding /// receptor signaling complex scaffold activity /// actinin binding | membrane fraction /// cytosol | --- | ---
AB002389 | KIAA0391 | KIAA0391 | 3_1 | 0.020430401 | decreased | 1.683388033623773 | 40073_at | --- | ENSG00000100890 | 458487 | 9692 | XM_375074 |  | --- | --- | --- | --- | ---
X90999 | hydroxyacylglutathione hydrolase | HAGH | 4_1 | 0.020226986 | decreased | 1.487205777451496 | 40120_at | 138760 | ENSG00000063854 | 157394 | 3029 | NM_005326 |  | --- | hydroxyacylglutathione hydrolase activity /// hydrolase activity | --- | Pyruvate metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00620+3.1.2.6
W28944 | glyoxylate reductase/hydroxypyruvate reductase | GRHPR | 10_1 | 0.038888857 | decreased | 1.27777472767532 | 40133_s_at | 260000 /// 604296 | ENSG00000137106 | 155742 | 9380 | NM_012203 |  | L-serine biosynthesis /// excretion /// metabolism | electron transporter activity /// oxidoreductase activity /// oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor /// glyoxylate reductase (NADP) activity | --- | Pyruvate metabolism /// Glyoxylate and dicarboxylate metabolism | www.genome.ad.jp/dbget-bin/show_pathway?MAP00620+1.1.1.79 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00630+1.1.1.79
L37042 | casein kinase 1, alpha 1 | CSNK1A1 | 2_5 | 0.037465499 | decreased | 2.137704390361036 | 40184_at | 600505 | ENSG00000113712 | 442592 | 1452 | NM_001892 |  | protein amino acid phosphorylation /// protein amino acid phosphorylation /// Wnt receptor signaling pathway | protein serine/threonine kinase activity /// casein kinase I activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity | --- | --- | ---
AI761647 | [NAME] | [NAME] | 7_1 | 0.021146028 | decreased | 1.634229147832417 | 40191_s_at | --- | ENSG00000011523 | 146007 | 23177 | NM_015147 |  | --- | --- | --- | --- | ---
AI743654 | metallophosphoesterase 1 | MPPE1 | 8_1 | 0.014705729 | decreased | 1.701948716316837 | 40244_s_at | --- | ENSG00000154889 | 514713 | 65258 | NM_023075 /// NM_138608 |  | DNA repair | endonuclease activity /// hydrolase activity | --- | --- | ---
U55766 | HIV-1 rev binding protein 2 | HRB2 | 4_3 | 0.040762518 | decreased | 1.598223390609699 | 40250_at | --- | ENSG00000111615 | 269857 | 11103 | NM_007043 |  | --- | nucleic acid binding | nucleus | --- | ---
[NAME] | Karyopherin alpha 6 (importin alpha 7) | [NAME] | 6_1 | 0.037362438 | decreased | 1.561163498430883 | 40275_at | --- | ENSG00000025800 | 470588 | 23633 | NM_012316 |  | NLS-bearing substrate-nucleus import /// intracellular protein transport | protein transporter activity | --- | --- | ---
AF052117 | Chloride channel 4 | CLCN4 | 3_1 | 0.03224345 | decreased | 0.9530878986393112 | 40335_at | 302910 | ENSG00000073464 | 495674 | 1183 | NM_001830 |  | ion transport /// chloride transport | voltage-gated chloride channel activity | membrane fraction /// integral to plasma membrane /// membrane | --- | ---
U66077 | deleted in azoospermia 1 /// deleted in azoospermia 3 /// deleted in azoospermia 2 /// deleted in azoospermia 4 | DAZ1 /// DAZ3 /// DAZ2 /// DAZ4 | 5_10 | 0.045541548 | increased | 1.198711406208589 | 40342_at | 400003 /// 400027 /// 400026 | ENSG00000187191 | 70936 | 1617 /// 57054 /// 57055 /// 57135 | /// NM_001005375 /// NM_001005785 /// NM_001005786 /// NM_004081 /// NM_020363 /// NM_020364 /// NM_020420 |  | spermatogenesis /// spermatogenesis /// fertilization (sensu Metazoa) /// cell differentiation | nucleotide binding /// [NAME] binding /// RNA binding | nucleus | --- | ---
AL049442 | carbonic reductase 4 | CBR4 | 7_1 | 0.013829596 | decreased | 1.53436362405515 | 40349_at | --- | ENSG00000145439 | 481166 | 84869 | NM_032783 |  | metabolism | oxidoreductase activity | --- | --- | ---
M91083 | chromosome 11 open reading frame 13 | [NAME] | 5_10 | 0.042402254 | increased | 1.401450430646911 | 40359_at | 143023 | [NAME] | 72925 | 8045 | NM_003475 |  | regulation of transcription, DNA-dependent /// signal transduction | DNA binding | nucleus | --- | ---
J05158 | --- | --- | 10_1 | 0.034187529 | decreased | 1.522783372362017 | 40368_r_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
X14813 | acetyl-Coenzyme A acyltransferase 1 (peroxisomal 3-oxoacyl-Coenzyme A thiolase) | ACAA1 | 6_1 | 0.007081076 | decreased | 1.685548927666898 | 40415_at | 261515 /// 604054 | ENSG00000060971 | 166160 | 30 | NM_001607 |  | generation of precursor metabolites and energy /// lipid metabolism /// fatty acid metabolism | acetyl-CoA C-acyltransferase activity /// acyltransferase activity /// transferase activity | peroxisome | Fatty acid biosynthesis (path 2) /// Fatty acid metabolism /// Bile acid biosynthesis /// [NAME], leucine and isoleucine degradation /// Benzoate degradation via hydroxylation | www.genome.ad.jp/dbget-bin/show_pathway?MAP00062+2.3.1.16 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00071+2.3.1.16 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00120+2.3.1.16 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00280+2.3.1.16 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00362+2.3.1.16
AB020710 | EH domain binding protein 1 | EHBP1 | 6_1 | 0.035452907 | decreased | 1.727233378095397 | 40423_at | --- | ENSG00000115504 | 271667 | 23301 | NM_015252 |  | --- | --- | --- | --- | ---
AF091085 | serologically defined breast cancer antigen 84 | SDBCAG84 | 6_1 | 0.009433866 | decreased | 1.035296930680955 | 40514_at | --- | ENSG00000125991 | 472558 | 51614 | NM_015966 /// NM_198398 |  | --- | --- | integral to membrane | --- | ---
AB002370 | --- | --- | 4_1 | 0.04855014 | decreased | 1.38976982276798 | 40517_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AI926989 | Similar to 2010300C02Rik protein | MGC42367 | 5_10 | 0.013193368 | increased | 1.413063024488345 | 40540_at | --- | ENSG00000196872 | 469398 | 343990 | NM_207362 |  | --- | --- | --- | --- | ---
AA631074 | T-cell leukemia, homeobox 2 | TLX2 | 10_1 | 0.029093043 | decreased | 1.390198411706588 | 40561_at | 604240 | ENSG00000115297 | 168586 | 3196 | [NAME] /// NM_016170 |  | regulation of transcription, DNA-dependent /// development | transcription factor activity | nucleus | --- | ---
Y13493 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | DYRK2 | 4_4 | 0.028162809 | decreased | 0.9177054790390712 | 40604_at | 603496 | ENSG00000127334 | 173135 | 8445 | NM_003583 /// NM_006482 |  | protein amino acid phosphorylation /// protein amino acid phosphorylation | magnesium ion binding /// protein serine/threonine kinase activity /// protein-tyrosine kinase activity /// ATP binding /// transferase activity /// manganese ion binding | cytoplasm | --- | ---
U97670 | eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa | EIF3S1 | 10_1 | 0.035943897 | decreased | 2.602073617077649 | 40616_at | 603910 | ENSG00000104131 | 404056 | 8669 | NM_003758 |  | protein biosynthesis /// regulation of translational initiation | translation initiation factor activity | eukaryotic translation initiation factor 3 complex | Translation_Factors | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Translation_Factors/Hs_Translation_Factors.htm
[NAME] | phosphatidylinositol glycan, class H | PIGH | 9_3 | 0.00940786 | decreased | 1.746772960607846 | 40629_at | 600154 | ENSG00000100564 | 284157 | 5283 | NM_004569 |  | protein modification /// GPI anchor biosynthesis | transferase activity, transferring glycosyl groups /// phosphatidylinositol N-acetylglucosaminyltransferase activity | endoplasmic reticulum | --- | ---
AI653713 | BCL2/adenovirus E1B 19kDa interacting protein 2 | BNIP2 | 10_1 | 0.035623557 | decreased | 1.106964918258644 | 40630_at | 603292 | ENSG00000140299 | 283454 | 663 | NM_004330 |  | apoptosis /// anti-apoptosis | GTPase activator activity | --- | --- | ---
AF039523 | corticotropin releasing hormone receptor 1 | CRHR1 | 5_10 | 0.039616392 | increased | 1.584287112690395 | 40651_s_at | 122561 | ENSG00000120088 | 417628 | 1394 | NM_004382 |  | immune response /// signal transduction /// G-protein coupled receptor protein signaling pathway /// G-protein signaling, coupled to cAMP nucleotide second messenger /// adenylate cyclase activation /// pregnancy /// parturition | receptor activity /// G-protein coupled receptor activity /// corticotrophin-releasing factor receptor activity | plasma membrane /// integral to plasma membrane /// membrane | GPCRDB_Class_B_Secretin-like /// Smooth_muscle_contraction | [NAME] /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
AF039918 | ectonucleoside triphosphate diphosphohydrolase 5 | ENTPD5 | 4_1 | 0.017624729 | decreased | 1.280420070364443 | 40666_at | 603162 | ENSG00000187097 | 131555 | 957 | NM_001249 |  | --- | magnesium ion binding /// hydrolase activity /// nucleoside-diphosphatase activity | endoplasmic reticulum /// integral to membrane | --- | ---
X54131 | protein tyrosine phosphatase, receptor type, B | PTPRB | 3_1 | 0.017474217 | decreased | 1.801873098487578 | 407_at | 176882 | ENSG00000127329 | 434375 | 5787 | NM_002837 |  | protein amino acid dephosphorylation /// phosphate metabolism | [NAME] receptor protein tyrosine phosphatase activity /// sugar binding /// hydrolase activity | membrane fraction /// integral to plasma membrane | --- | ---
U75362 | ubiquitin specific protease 13 (isopeptidase T-3) | USP13 | 10_1 | 0.052114546 | decreased | 1.28335107147374 | 40701_at | 603591 | ENSG00000058056 | 175322 | 8975 | NM_003940 |  | ubiquitin-dependent protein catabolism /// ubiquitin cycle | cysteine-type endopeptidase activity /// ubiquitin thiolesterase activity | --- | --- | ---
AL022398 | TRAF3-interacting [NAME] kinase (JNK)-activating modulator | T3JAM | 4_1 | 0.039428012 | decreased | 1.222262944470992 | 40720_at | 608255 | ENSG00000009790 | 147434 | 80342 | NM_025228 |  | --- | --- | integral to membrane | --- | ---
M30185 | cholesteryl ester transfer protein, plasma | CETP | 10_1 | 0.030203543 | decreased | 1.112996528715384 | 40741_at | 118470 /// 143470 /// 152430 /// 607322 | ENSG00000087237 | 89538 | 1071 | NM_000078 |  | lipid metabolism /// lipid transport /// steroid metabolism /// cholesterol metabolism | catalytic activity /// lipid binding | --- | Statin_Pathway_PharmGKB | [NAME]
U90911 | WIRE protein | WIRE | 6_1 | 0.026640323 | decreased | 2.217659547067743 | 40787_at | --- | ENSG00000171475 | 421622 | 147179 | NM_133264 |  | --- | [NAME] binding | --- | --- | ---
M61832 | S-adenosylhomocysteine hydrolase | AHCY | 9_1 | 0.029874056 | decreased | 1.570244872995485 | 40821_at | 180960 | ENSG00000101444 | 388004 | 191 | NM_000687 |  | one-carbon compound metabolism | adenosylhomocysteinase activity /// hydrolase activity | cytoplasm | Methionine metabolism /// Selenoamino acid metabolism | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00450+3.3.1.1
AB018288 | exportin 7 | XPO7 | 7_1 | 0.004970871 | decreased | 1.882815660721753 | 40824_at | 606140 | ENSG00000130227 | 172685 | 23039 | NM_015024 |  | protein-nucleus import, docking /// protein-nucleus export /// protein transport | nuclear export signal receptor activity /// binding /// protein transporter activity | nucleus /// nuclear pore /// cytoplasm | --- | ---
AB025254 | [NAME] domain containing 7 | TDRD7 | 6_1 | 0.02512339 | decreased | 1.591319678533943 | 40852_at | --- | ENSG00000196116 | 193842 | 23424 | NM_014290 |  | --- | nucleic acid binding | --- | --- | ---
W25821 | Nuclear protein UKp68 | FLJ11806 | 10_1 | 0.029775275 | decreased | 1.095396461421423 | 40860_s_at | --- | ENSG00000100722 | 325846 | 79882 | NM_024824 /// NM_207660 /// NM_207661 /// NM_207662 |  | --- | nucleic acid binding | nucleus | --- | ---
W28230 | Syntaxin 16 | STX16 | 1_10 | 0.009780848 | increased | 1.430391670769064 | 40884_g_at | 603666 | ENSG00000124222 | 307913 | 8675 | NM_001001433 /// NM_001001434 /// NM_003763 |  | intracellular protein transport /// intra-Golgi transport | t-SNARE activity /// protein transporter activity | microsome /// Golgi apparatus /// Golgi stack /// membrane /// integral to membrane | --- | ---
W28588 | Neurofilament, light polypeptide 68kDa | NEFL | 5_10 | 0.027260978 | increased | 1.573280306186528 | 40996_s_at | 162280 /// 607684 /// 607734 | ENSG00000104725 | 521461 | 4747 | NM_006158 |  | --- | structural molecule activity /// structural constituent of cytoskeleton /// protein binding | intermediate filament /// neurofilament /// axon | --- | ---
X87344 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7) | PSMB8 | 6_1 | 0.01793736 | decreased | 2.175954387235813 | 41184_s_at | 177046 | ENSG00000168396 | 180062 | 5696 | NM_004159 /// NM_148919 |  | proteolysis and peptidolysis /// ubiquitin-dependent protein catabolism /// immune response | threonine endopeptidase activity | proteasome core complex (sensu [NAME]) | Proteasome_Degradation /// Proteasome | [NAME] /// www.genome.ad.jp/dbget-bin/show_pathway?MAP03050+3.4.25.1
AF043897 | chromosome 9 open reading frame 3 | C9orf3 | 10_1 | 0.039665236 | decreased | 1.977228214238119 | 41207_at | --- | ENSG00000148120 | 434253 | 84909 | NM_032823 |  | proteolysis and peptidolysis | aminopeptidase activity /// membrane alanyl aminopeptidase activity /// metallopeptidase activity | --- | --- | ---
M58459 | ribosomal protein S4, Y-linked 1 | RPS4Y1 | 5_10 | 0.001948776 | increased | 1.784946168831362 | 41214_at | 470000 | ENSG00000129824 | 282376 | 6192 | NM_001008 |  | protein biosynthesis | RNA binding /// structural constituent of ribosome | ribosome /// cytosolic small ribosomal subunit (sensu [NAME]) | Ribosomal_Proteins | www.genmapp.org/HTML_MAPPs/Human/molecular_function_GenMAPP/Hs_Ribosomal_Proteins/Hs_Ribosomal_Proteins.htm
AI222594 | Nuclear factor I/B | NFIB | 2_1 | 0.011227341 | decreased | 1.697894355899246 | 41229_at | 600728 | ENSG00000147862 | 370359 | 4781 | NM_005596 |  | DNA replication /// transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// transcription factor activity | nucleus /// nucleus | --- | ---
L40410 | thyroid hormone receptor interactor 3 | TRIP3 | 9_1 | 0.014252342 | decreased | 2.000646816804948 | 41251_at | 604500 | ENSG00000108278 | 2210 | 9326 | NM_004773 |  | regulation of transcription, DNA-dependent | thyroid hormone receptor binding | intracellular | --- | ---
AB028972 | KIAA1049 protein | [NAME] | 9_1 | 0.023056547 | decreased | 2.306508898911395 | 41267_at | --- | ENSG00000141002 | 415342 | 22980 | NM_014972 |  | --- | binding | --- | --- | ---
AL036744 | calmodulin 1 (phosphorylase kinase, delta) | [NAME] | 6_1 | 0.046590126 | decreased | 1.167828249093757 | 41288_at | 114180 | ENSG00000198668 /// ENSG00000143933 /// ENSG00000160014 | 282410 | 801 | NM_006888 |  | --- | --- | --- | G_Protein_Signaling /// G13_Signaling_Pathway /// Glycogen_Metabolism /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction | [NAME] /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G13_Signaling_Pathway/Hs_G13_Signaling_Pathway.htm /// www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Glycogen_Metabolism/Hs_Glycogen_Metabolism.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
W28183 | --- | --- | 10_1 | 0.043623255 | decreased | 1.206421527742413 | 41299_f_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
W29042 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1 | NDUFAF1 | 10_1 | 0.025140773 | decreased | 1.14811865927298 | 41410_at | 606934 | ENSG00000137806 | 106529 | 51103 | NM_016013 |  | mitochondrial electron transport, NADH to ubiquinone /// protein folding /// protein complex assembly | unfolded protein binding | mitochondrion /// respiratory chain complex I (sensu Eukaryota) | --- | ---
AL023553 | RNA-binding protein pippin | PIPPIN | 10_3 | 0.046626228 | decreased | 2.292210258411698 | 41412_at | --- | ENSG00000172346 | 310893 | 27254 | NM_014460 |  | regulation of transcription, DNA-dependent /// mRNA processing /// histone mRNA 3'-end processing | DNA binding /// [NAME] binding | nucleus /// cytoplasm | --- | ---
L48516 | paraoxonase 3 | PON3 | 10_1 | 0.028050862 | decreased | 1.396164471627091 | 41424_at | 602720 | ENSG00000105852 | 440967 | 5446 | NM_000940 |  | response to external stimulus | arylesterase activity /// hydrolase activity | extracellular region | --- | ---
AJ000534 | sarcoglycan, epsilon | SGCE | 9_1 | 0.048097963 | decreased | 1.822904838676398 | 41449_at | 159900 /// 604149 | ENSG00000127990 | 371199 | 8910 | NM_003919 |  | cell-matrix adhesion /// muscle development | calcium ion binding /// protein binding | cytoskeleton /// integral to plasma membrane /// sarcoglycan complex | --- | ---
AB023232 | zinc finger protein 95 homolog (mouse) | ZFP95 | 7_1 | 0.017521731 | decreased | 1.427237955594956 | 41452_at | --- | ENSG00000196652 | 110839 | 23660 | /// NM_014569 /// NM_145102 |  | transcription /// regulation of transcription, DNA-dependent /// regulation of transcription, DNA-dependent | nucleic acid binding /// transcription factor activity /// transcription factor activity /// zinc ion binding /// zinc ion binding | nucleus /// nucleus | --- | ---
U49089 | discs, large homolog 3 (neuroendocrine-dlg, Drosophila) | DLG3 | 7_1 | 0.044182102 | decreased | 1.361782317667176 | 41453_at | 300189 | ENSG00000082458 | 522680 | 1741 | NM_021120 |  | negative regulation of cell proliferation | guanylate kinase activity /// protein binding | --- | --- | ---
AB018255 | Rho GTPase-activating protein | [NAME] | 6_1 | 0.018333567 | decreased | 3.176859299785143 | 41455_at | 608541 | ENSG00000134909 | 440379 | 9743 | NM_014715 |  | --- | GTPase activator activity | --- | --- | ---
AL078641 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G | APOBEC3G | 6_1 | 0.048833195 | decreased | 1.134561043034529 | 41472_at | 607113 | ENSG00000128394 | 474853 | 60489 | NM_021822 |  | RNA metabolism /// innate immune response /// negative regulation of retroviral genome replication | RNA binding /// cytidine deaminase activity /// zinc ion binding /// hydrolase activity /// protein homodimerization activity | nucleus | --- | ---
AB028944 | ATPase, Class VI, type 11A | ATP11A | 5_10 | 0.05184406 | increased | 1.92322393434231 | 41491_s_at | 605868 | ENSG00000068650 | 29189 | 23250 | NM_015205 /// NM_032189 |  | cation transport /// metabolism | magnesium ion binding /// catalytic activity /// phospholipid-translocating ATPase activity /// ATP binding /// ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism /// hydrolase activity /// ATPase activity | membrane /// integral to membrane | --- | ---
U20647 | zinc finger and BTB domain containing 17 | ZBTB17 | 1_10 | 0.049671718 | increased | 1.133482270044315 | 41532_at | 604084 | ENSG00000116809 | 433764 | 7709 | NM_003443 |  | transcription /// regulation of transcription, DNA-dependent /// negative regulation of cell cycle | transcription factor activity /// protein binding /// zinc ion binding | nucleus | --- | ---
Z50749 | protein phosphatase 1, regulatory subunit 7 | PPP1R7 | 7_1 | 0.015962629 | decreased | 1.412923791213599 | 41540_at | 602877 | ENSG00000115685 | 36587 | 5510 | NM_002712 |  | --- | protein phosphatase type 1 regulator activity /// enzyme regulator activity | nucleus /// cytoplasm | --- | ---
AF070571 | Clone 24739 mRNA sequence | --- | 5_10 | 0.019755801 | increased | 1.355355228260798 | 41575_at | --- | --- | 44690 | --- | --- |  | --- | --- | --- | --- | ---
AI652660 | tetratricopeptide repeat domain 15 | TTC15 | 3_1 | 0.022781061 | decreased | 1.901590073805242 | 41590_at | --- | ENSG00000171853 | 252713 | 51112 | NM_016030 |  | --- | binding | --- | --- | ---
AA890010 | SEC22 vesicle trafficking protein-like 1 (S. cerevisiae) | SEC22L1 | 1_10 | 0.03980932 | increased | 1.597073440164205 | 41598_at | 604029 | ENSG00000155878 | 534212 | 9554 | NM_004892 |  | ER to Golgi transport /// protein transport /// vesicle-mediated transport | --- | endoplasmic reticulum membrane /// Golgi apparatus /// integral to membrane | --- | ---
U87954 | --- | --- | 2_5 | 0.042012286 | decreased | 1.505544761981192 | 41600_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
AI349593 | hemoglobin, epsilon 1 | HBE1 | 5_10 | 0.045357856 | increased | 1.011309647947205 | 41617_at | 142100 | ENSG00000196565 | 117848 | 3046 | /// NM_005330 |  | transport /// oxygen transport | oxygen transporter activity /// oxygen binding /// heme binding | hemoglobin complex | --- | ---
X65293 | [NAME], epsilon | PRKCE | 4_4 | 0.003288782 | decreased | 1.353386059840786 | 417_at | 176975 | ENSG00000171132 | 97432 | 5581 | NM_005400 |  | protein amino acid phosphorylation /// induction of apoptosis /// intracellular signaling cascade | protein kinase C activity /// signal transducer activity /// ATP binding /// transferase activity /// diacylglycerol binding | membrane fraction | G_Protein_Signaling /// Wnt_signaling /// Calcium_regulation_in_cardiac_cells /// Smooth_muscle_contraction | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G_Protein_Signaling/Hs_G_Protein_Signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_Wnt_signaling/Hs_Wnt_signaling.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Calcium_regulation_in_cardiac_cells/Hs_Calcium_regulation_in_cardiac_cells.htm /// www.genmapp.org/HTML_MAPPs/Human/physiological_process-GenMAPP/Hs_Smooth_muscle_contraction/Hs_Smooth_muscle_contraction.htm
AF034803 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | PPFIBP2 | 7_1 | 0.017698876 | decreased | 1.60241258564017 | 41709_at | 603142 | ENSG00000166387 | 16019 | 8495 | NM_003621 |  | cell communication | --- | intracellular | --- | ---
U09848 | zinc finger with KRAB and SCAN domains 1 | [NAME] | 7_1 | 0.024364155 | decreased | 1.225714523448162 | 41713_at | 601260 | ENSG00000106261 | 423725 | 7586 | NM_003439 |  | transcription /// regulation of transcription, DNA-dependent /// regulation of transcription, DNA-dependent | nucleic acid binding /// transcription factor activity /// transcription factor activity /// zinc ion binding | nucleus /// nucleus | --- | ---
AI808958 | KIAA0870 protein | KIAA0870 | 5_10 | 0.01435947 | increased | 1.635702726399534 | 41736_g_at | --- | ENSG00000105339 | 18166 | 22898 | NM_014957 |  | signal transduction | signal transducer activity | --- | --- | ---
U79278 | protein disulfide isomerase-associated 6 | PDIA6 | 4_1 | 0.012468712 | decreased | 1.538897887481166 | 41751_at | --- | ENSG00000143870 | 212102 | 10130 | NM_005742 |  | electron transport /// protein folding | protein disulfide isomerase activity /// electron transporter activity /// isomerase activity | endoplasmic reticulum | --- | ---
AA978033 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | COX7A2 | 9_1 | 0.045363888 | decreased | 2.811814323737374 | 41760_at | 123996 | ENSG00000112695 | 70312 | 1347 | NM_001865 |  | electron transport | cytochrome-c oxidase activity /// electron transporter activity /// oxidoreductase activity | mitochondrion /// inner membrane | Electron_Transport_Chain /// Oxidative phosphorylation | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Electron_Transport_Chain/Hs_Electron_Transport_Chain.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00190+1.9.3.1
U96781 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | ATP2A1 | 10_1 | 0.050587052 | decreased | 0.8787440901029572 | 41769_at | 108730 /// 601003 | ENSG00000196296 | 550464 | 487 | NM_004320 /// NM_173201 |  | cation transport /// calcium ion transport /// regulation of striated muscle contraction /// metabolism /// proton transport | magnesium ion binding /// calcium-transporting ATPase activity /// calcium ion binding /// ATP binding /// hydrolase activity /// hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | smooth endoplasmic reticulum /// membrane /// integral to membrane | --- | ---
AA420624 | monoamine oxidase A | MAOA | 6_1 | 0.01586458 | decreased | 1.636436924451592 | 41770_at | 309850 | ENSG00000189221 | 183109 | 4128 | NM_000240 |  | electron transport /// catecholamine metabolism /// behavior /// neurotransmitter catabolism | amine oxidase activity /// oxidoreductase activity | mitochondrion /// membrane /// integral to membrane | Biogenic_Amine_Synthesis /// Glycine, serine and threonine metabolism /// Arginine and proline metabolism /// Histidine metabolism /// Tyrosine metabolism /// Phenylalanine metabolism /// Tryptophan metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Biogenic_Amine_Synthesis/Hs_Biogenic_Amine_Synthesis.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00260+1.4.3.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00330+1.4.3.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00340+1.4.3.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00350+1.4.3.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00360+1.4.3.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+1.4.3.4
AA420624 | monoamine oxidase A | MAOA | 8_1 | 0.015810101 | decreased | 1.503937802354334 | 41771_g_at | 309850 | ENSG00000189221 | 183109 | 4128 | NM_000240 |  | electron transport /// catecholamine metabolism /// behavior /// neurotransmitter catabolism | amine oxidase activity /// oxidoreductase activity | mitochondrion /// membrane /// integral to membrane | Biogenic_Amine_Synthesis /// Glycine, serine and threonine metabolism /// Arginine and proline metabolism /// Histidine metabolism /// Tyrosine metabolism /// Phenylalanine metabolism /// Tryptophan metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Biogenic_Amine_Synthesis/Hs_Biogenic_Amine_Synthesis.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00260+1.4.3.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00330+1.4.3.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00340+1.4.3.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00350+1.4.3.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00360+1.4.3.4 /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00380+1.4.3.4
AI656421 | chromosome 7 open reading frame 23 | C7orf23 | 10_1 | 0.01543889 | decreased | 1.505366317151167 | 41809_at | --- | ENSG00000135185 | 196129 | 79161 | NM_024315 |  | --- | --- | integral to membrane | --- | ---
AA149431 | chromosome 14 open reading frame 132 | C14orf132 | 8_1 | 0.037256328 | decreased | 1.200839571042484 | 41837_at | --- | ENSG00000183633 | 6434 | 56967 | NM_020215 |  | --- | --- | integral to membrane | --- | ---
AF052138 | Bromodomain containing 3 | BRD3 | 9_1 | 0.030297634 | decreased | 1.611956905164697 | 41841_at | 601541 | ENSG00000169925 | 522472 | 8019 | NM_007371 |  | --- | --- | nucleus | --- | ---
W29036 | cone-rod homeobox | CRX | 9_1 | 0.050876209 | decreased | 3.046823624725185 | 41845_at | 120970 /// 204000 /// 268000 /// 602225 | ENSG00000105392 | 249186 | 1406 | NM_000554 |  | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter /// sensory perception /// visual perception /// organogenesis | transcription factor activity | nucleus | --- | ---
AF055009 | cAMP responsive element binding protein 3-like 1 | CREB3L1 | 9_3 | 0.044442894 | decreased | 2.556274887115089 | 41867_at | --- | ENSG00000157613 | 405961 | 90993 | NM_052854 |  | regulation of transcription, DNA-dependent | transcription factor activity | nucleus | G1_to_S_cell_cycle_Reactome | www.genmapp.org/HTML_MAPPs/Human/cellular_process-GenMAPP/Hs_G1_to_S_cell_cycle_Reactome/Hs_G1_to_S_cell_cycle_Reactome.htm
U48730 | signal transducer and activator of transcription 5B | STAT5B | 1_10 | 0.028926692 | increased | 1.413018012310638 | 472_at | 245590 /// 604260 | ENSG00000173757 | 132864 | 6777 | [NAME] |  | transcription /// regulation of transcription from RNA polymerase II promoter /// intracellular signaling cascade /// JAK-STAT cascade | transcription factor activity /// signal transducer activity /// calcium ion binding | nucleus | --- | ---
U33821 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | TAX1BP1 | 3_2 | 0.032375725 | decreased | 1.742062630110421 | 498_at | 605326 | ENSG00000106052 | 34576 | 8887 | NM_006024 |  | anti-apoptosis | nucleic acid binding /// zinc ion binding | nucleus | --- | ---
U07132 | nuclear receptor subfamily 1, group H, member 2 | NR1H2 | 6_1 | 0.031522795 | decreased | 1.515073628033795 | 518_at | 600380 | ENSG00000131408 | 432976 | 7376 | NM_007121 |  | transcription /// regulation of transcription, DNA-dependent | transcription factor activity /// steroid hormone receptor activity | nucleus | Nuclear_Receptors | [NAME]
M31153 | cytochrome P450, family 17, subfamily A, polypeptide 1 | CYP17A1 | 5_10 | 0.04862325 | increased | 1.72828192592339 | 586_s_at | 202110 | ENSG00000148795 | 438016 | 1586 | NM_000102 |  | electron transport /// C21-steroid hormone biosynthesis /// transport /// sex differentiation | monooxygenase activity /// steroid 17-alpha-monooxygenase activity /// oxygen binding | endoplasmic reticulum /// microsome /// membrane | Glucocorticoid_Mineralocorticoid_Metabolism /// Steroid_Biosynthesis /// C21-Steroid hormone metabolism | www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Glucocorticoid_Mineralocorticoid_Metabolism/Hs_Glucocorticoid_Mineralocorticoid_Metabolism.htm /// www.genmapp.org/HTML_MAPPs/Human/metabolic_process-GenMAPP/Hs_Steroid_Biosynthesis/Hs_Steroid_Biosynthesis.htm /// www.genome.ad.jp/dbget-bin/show_pathway?MAP00140+1.14.99.9
M33684 | protein tyrosine phosphatase, non-receptor type 1 | PTPN1 | 1_10 | 0.036574804 | increased | 1.409738059092518 | 591_s_at | 176885 | ENSG00000196396 | 417549 | 5770 | NM_002827 |  | protein amino acid dephosphorylation /// signal transduction | protein tyrosine phosphatase activity /// hydrolase activity | soluble fraction /// cytoplasm | --- | ---
L78833 | vesicle amine transport protein 1 homolog (T californica) | VAT1 | 6_1 | 0.035286698 | decreased | 1.844776707052218 | 605_at | 604631 | ENSG00000108828 | 514199 | 10493 | NM_006373 |  | cell growth | DNA binding /// zinc ion binding /// oxidoreductase activity | nucleus /// synaptic vesicle /// integral to membrane | --- | ---
M24748 | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | THRA | 2_3 | 0.050640443 | decreased | 2.627389270392887 | 616_s_at | 190120 | ENSG00000126351 | 724 | 7067 | NM_003250 /// NM_199334 |  | regulation of transcription, DNA-dependent /// transcription from RNA polymerase II promoter | transcription factor activity /// steroid hormone receptor activity /// thyroid hormone receptor activity | nucleus | Nuclear_Receptors | [NAME]
[NAME] | --- | --- | 7_1 | 0.024334723 | decreased | 1.508331796590413 | 637_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
[NAME] | retinol binding protein 3, interstitial | RBP3 | 5_10 | 0.035914634 | increased | 1.011090362180289 | 680_s_at | 180290 | ENSG00000107618 | 114762 | 5949 | NM_002900 |  | proteolysis and peptidolysis /// lipid metabolism /// transport /// visual perception | retinoid binding /// fatty acid binding /// serine-type peptidase activity | extracellular matrix ([NAME]) | --- | ---
[NAME] | endogenous retroviral sequence K, 6 | ERVK6 | 10_1 | 0.047159844 | decreased | 1.3549434284195 | 686_s_at | 605626 | ENSG00000196413 | --- | 64006 | NM_001007236 |  | RNA-dependent DNA replication /// DNA transposition /// proteolysis and peptidolysis /// viral life cycle | nucleic acid binding /// [NAME] binding /// RNA-directed DNA polymerase activity /// aspartic-type endopeptidase activity /// peptidase activity /// transferase activity | intracellular /// membrane /// viral capsid | --- | ---
HG1751-HT1768 | --- | --- | 3_1 | 0.01181144 | decreased | 1.546682221313172 | 726_f_at | --- | --- | --- | --- | --- |  | --- | --- | --- | --- | ---
D85418 | phosphatidylinositol glycan, class C | PIGC | 10_1 | 0.032777792 | decreased | 1.118667295196279 | 751_at | 601730 | ENSG00000135845 | 188456 | 5279 | NM_002642 /// NM_153747 |  | GPI anchor biosynthesis | transferase activity, transferring glycosyl groups /// phosphatidylinositol N-acetylglucosaminyltransferase activity | endoplasmic reticulum membrane /// integral to membrane | --- | ---
X80343 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | CDK5R1 | 5_10 | 0.048903592 | increased | 1.143907471607398 | 800_g_at | 603460 | ENSG00000176749 | 500015 | 8851 | NM_003885 |  | regulation of cyclin dependent protein kinase activity /// brain development /// cell proliferation /// regulation of neuron differentiation | protein kinase activity /// protein binding /// kinase activity /// cyclin-dependent protein kinase 5 activator activity | cyclin-dependent protein kinase 5 activator complex | --- | ---
L02785 | solute carrier family 26, member 3 | SLC26A3 | 9_1 | 0.026726079 | decreased | 1.472165449692413 | 928_at | 126650 | ENSG00000091138 | 1650 | 1811 | NM_000111 |  | transport /// anion transport /// excretion /// sulfate transport | transcription factor activity /// transcription cofactor activity /// transporter activity /// sulfate porter activity /// antiporter activity | membrane fraction /// membrane /// integral to membrane | --- | ---
D63861 | peptidylprolyl isomerase D (cyclophilin D) | PPID | 6_1 | 0.017632508 | decreased | 1.637811572517194 | 948_s_at | 601753 | ENSG00000171497 | 183958 | 5481 | NM_005038 |  | protein folding | peptidyl-prolyl cis-trans isomerase activity /// FK506 binding /// cyclosporin A binding /// isomerase activity | --- | --- | ---
X98296 | ubiquitin specific protease 9, X-linked (fat facets-like, Drosophila) | USP9X | 4_1 | 0.038959824 | decreased | 1.618161800617759 | 968_i_at | 300072 | ENSG00000124486 | 77578 | 8239 | NM_004652 /// NM_021906 |  | ubiquitin-dependent protein catabolism /// ubiquitin cycle /// female gamete generation | cysteine-type endopeptidase activity /// ubiquitin thiolesterase activity | --- | --- | ---