Spreadsheet: 4b561611-7cba-4c3e-98d8-156bd2fe099e
Sheet: Sheet1

Table S9: Analyses of genes and clusters involved in secondary metabolite production | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11
Pfam ID | Domain description | Piri | Coci | Labi | Usti | Cryne | Pugr | Trire | Asni | Fusox | Tume
Non-ribosomal Peptide Synthetases (NRPS)
PF00106 | short chain dehydrogenase | 52 | 55 | 65 | 45 | 37 | 31 | 126 | 152 | 239 | 48
PF08241 | Methyltransferase domain type 11 | 32 | 22 | 22 | 13 | 9 | 11 | 33 | 28 | 78 | 25
PF08242 | Methyltransferase domain type 12 | 19 | 4 | 3 | 3 | 1 | 1 | 12 | 21 | 19 | 2
PF01370 | NAD dependent epimerase/dehydratase family | 16 | 14 | 12 | 7 | 13 | 5 | 20 | 18 | 48 | 8
PF07992 | Pyridine nucleotide-disulphide oxidoreductase | 15 | 20 | 13 | 15 | 14 | 11 | 19 | 27 | 41 | 13
PF00501 | AMP-binding enzyme | 13 | 32 | 33 | 30 | 9 | 12 | 38 | 68 | 75 | 22
PF01794 | Ferric reductase like transmembrane component | 8 | 9 | 7 | 7 | 7 | 8 | 12 | 10 | 15 | 8
PF00550 | Phosphopantetheine attachment site | 3 | 6 | 6 | 12 | 4 | 3 | 26 | 50 | 32 | 8
PF01073 | 3-beta hydroxysteroid dehydrogenase/isomerase family | 2 | 7 | 2 | 2 | 2 | 2 | 4 | 4 | 7 | 1
PF07993 | Male sterility protein | 2 | 5 | 7 | 8 | 2 | 1 | 10 | 22 | 14 | 4
PF00132 | Bacterial transferase hexapeptide (three repeats) | 1 | 2 | 1 | 1 | 5 | 5 | 1 | 4 | 6 | 2
PF00668 | Condensation domain* | 0 | 1 | 1 | 3 | 0 | 1 | 10 | 19 | 14 | 1
PF00975 | Thioesterase domain* | 0 | 2 | 1 | 3 | 0 | 1 | 3 | 7 | 2 | 1
Polyketide Synthase (PKS)
PF08240 | Alcohol dehydrogenase GroES-like domain | 14 | 24 | 25 | 22 | 23 | 11 | 43 | 57 | 113 | 11
PF02801 | Beta-ketoacyl synthase, C-terminal domain | 1 | 3 | 3 | 5 | 1 | 2 | 15 | 37 | 16 | 4
NRPS & PKS
PF00698 | Acyl transferase domain | 1 | 3 | 2 | 5 | 1 | 4 | 17 | 36 | 18 | 9
PF00109 | Beta-ketoacyl synthase, N-terminal domain | 1 | 2 | 4 | 5 | 1 | 2 | 17 | 37 | 17 | 5
PF08659 | KR domain | 0 | 2 | 1 | 0 | 0 | 0 | 9 | 16 | 13 | 1
 |  | 180 | 213 | 208 | 186 | 129 | 111 | 415 | 613 | 767 | 173
*essential for NRPS
1Piriformospora indica
2Coprinus cinerea
3Laccaria bicolor
4Ustilago maydis
5Cryptococcus neoformans
6Puccinia graminis
7Trichoderma reesei
8Aspergillus nidulans
9Fusarium oxysporum
10Tuber melanosporum
Searches for known clusters involved in toxin production
F. verticilliodes fumonisin cluster
not present.  6/15 genes from the fumonisin cluster do not have blast hits to P. indica.  Best hits for the other genes are scattered on different contigs.
F. graminearum trichothecene cluster
not present.  10/12 genes from the cluster do not have blast hits to P. indica.  Best hits for the other genes are scattered on different contigs.
F. graminearum zearalenone cluster
not present.  4/10 genes from the cluster do not have blast hits to P. indica.  Best hits for the other genes are scattered on different contigs.
F. graminearum butenolide cluster
not present.  5/8 genes from the cluster do not have blast hits to P. indica.  Best hits for the other genes are scattered on different contigs.
F. graminearum aurofusarin cluster
not present.  7/11 genes from the cluster do not have blast hits to P. indica.  Best hits for the other genes are scattered on different contigs.
A. nidulans terrequinone cluster
not present.  4/5 genes from the cluster do not have blast hits to P. indica.  Best hits for the other genes are scattered on different contigs.
A. nidulans asperfuranone cluster
not present.  6/13 genes from the cluster do not have blast hits to P. indica.  Best hits for the other genes are scattered on different contigs.
A. nidulans sterigmatocystin cluster
not present.  9/17 genes from the cluster do not have blast hits to P. indica.  Best hits for the other genes are scattered on different contigs.
H. cylindrosporum Nrt2 cluster
not present. 3 genes from the cluster do not have blast hits to P. indica.
U. maydis Mig2-5 cluster
not present.