Spreadsheet: 436d7bc9-5378-4827-9398-8286b4a54967
Sheet: Sheet1

Suppelemtary Table S3
668 Pfam  entries virus-metazoa cross-taxon
ID | NAME | #[NAME] | AVG_METAZOA_PROT_LENGTHS | AVG_METAZOA_DOMAIN_NUM | AVG_METAZOA_DISTINCT_DOMAIN_NUM | #VIRUSES_PROTS | AVG_VIRUS_PROT_LENGTHS | AVG_VIR_DOMAIN_NUM | AVG_VIR_DISTINCT_DOMAIN_NUM | #BACTERIA_OR_FUNGI_PROTS | #METAZOA_VIRUSES | family size | % of viral/ family | % of viral/ metazoan proteins | % of viral/ [NAME] proteins
HALZ | Homeobox associated leucine zipper | 4 | 335 | 1 | 1 | 1 | 103 | 1 | 1 | 2 | 0 | 7 | 14.28571428571428 | 25 | 20
PC4 | Transcriptional Coactivator p15 (PC4) | 62 | 123.452 | 1 | 1 | 1 | 102 | 1 | 1 | 65 | 0 | 128 | 0.78125 | 1.612903225806452 | 1.587301587301587
Archease | Archease protein family (DUF101/UPF0211) | 43 | 153.116 | 1 | 1 | 1 | 143 | 1 | 1 | 76 | 0 | 120 | 0.8333333333333334 | 2.325581395348837 | 2.272727272727273
Sds3 | Sds3-like | 91 | 285.165 | 1 | 1 | 1 | 938 | 1 | 1 | 117 | 0 | 209 | 0.4784688995215311 | 1.098901098901099 | 1.08695652173913
Heme_oxygenase | Heme oxygenase | 76 | 258.184 | 1 | 1 | 1 | 233 | 1 | 1 | 334 | 0 | 411 | 0.24330900243309 | 1.31578947368421 | 1.298701298701299
OCD_Mu_crystall | Ornithine cyclodeaminase/[NAME] family | 38 | 314.789 | 1 | 1 | 1 | 91 | 1 | 1 | 953 | 0 | 992 | 0.1008064516129032 | 2.631578947368421 | 2.564102564102564
Abhydrolase_2 | Phospholipase/Carboxylesterase | 107 | 226.421 | 1 | 1 | 1 | 312 | 1 | 1 | 1307 | 0 | 1415 | 0.0706713780918728 | 0.9345794392523363 | 0.9259259259259258
DHQ_synthase | 3-dehydroquinate synthase | 4 | 283.25 | 1 | 1 | 1 | 338 | 1 | 1 | 1632 | 0 | 1637 | 0.06108735491753207 | 25 | 20
Glyco_transf_17 | Glycosyltransferase family 17 | 32 | 490.531 | 1 | 1 | 2 | 270 | 1 | 1 | 27 | 0 | 61 | 3.278688524590164 | 6.25 | 5.88235294117647
DUF3472 | Domain of unknown function (DUF3472) | 9 | 298.556 | 1 | 1 | 2 | 245 | 1 | 1 | 91 | 0 | 102 | 1.96078431372549 | 22.22222222222222 | 18.18181818181818
Acetyltransf_2 | N-acetyltransferase | 96 | 277.417 | 1 | 1 | 2 | 208 | 1 | 1 | 611 | 0 | 709 | 0.2820874471086037 | 2.083333333333333 | 2.040816326530612
DegT_DnrJ_EryC1 | DegT/DnrJ/EryC1/StrS aminotransferase family | 3 | 429 | 1 | 1 | 2 | 365.5 | 1 | 1 | 2941 | 0 | 2946 | 0.0678886625933469 | 66.66666666666666 | 40
IL17 | Interleukin-17 | 78 | 163.385 | 1 | 1 | 3 | 151 | 1 | 1 | 0 | 0 | 81 | 3.703703703703703 | 3.846153846153846 | 3.703703703703703
Chloroa_b-bind | Chlorophyll A-B binding protein | 4 | 111.75 | 1 | 1 | 3 | 36.667 | 1 | 1 | 297 | 0 | 304 | 0.9868421052631579 | 75 | 42.85714285714285
TauE | Sulfite exporter TauE/SafE | 11 | 319.182 | 1 | 1 | 3 | 252 | 1 | 1 | 4385 | 0 | 4399 | 0.0681973175721755 | 27.27272727272727 | 21.42857142857143
PTPS | 6-pyruvoyl tetrahydropterin synthase | 42 | 151.857 | 1 | 1 | 4 | 186.75 | 1 | 1 | 1185 | 0 | 1231 | 0.3249390739236393 | 9.523809523809524 | 8.695652173913043
PRP1_N | PRP1 splicing factor, N-terminal | 42 | 853.262 | 1 | 1 | 5 | 77.8 | 1 | 1 | 59 | 0 | 106 | 4.716981132075472 | 11.9047619047619 | 10.63829787234043
Nuc_deoxyrib_tr | Nucleoside 2-deoxyribosyltransferase | 10 | 148.4 | 1 | 1 | 5 | 154.8 | 1 | 1 | 388 | 0 | 403 | 1.240694789081886 | 50 | 33.33333333333333
PAD_porph | Porphyromonas-type peptidyl-arginine deiminase | 3 | 357 | 1 | 1 | 5 | 360.4 | 1 | 1 | 630 | 0 | 638 | 0.7836990595611284 | 166.6666666666667 | 62.5
GTP_cyclohydroI | GTP cyclohydrolase I | 51 | 244.314 | 1 | 1 | 5 | 229 | 1 | 1 | 2271 | 0 | 2327 | 0.2148689299527289 | 9.803921568627452 | 8.928571428571429
Mpv17_PMP22 | Mpv17 / PMP22 family | 236 | 196.182 | 1 | 1 | 6 | 165.333 | 1 | 1 | 250 | 0 | 492 | 1.219512195121951 | 2.542372881355933 | 2.479338842975207
IL6 | Interleukin-6/G-CSF/MGF family | 126 | 183.183 | 1 | 1 | 10 | 205.9 | 1 | 1 | 0 | 0 | 136 | 7.352941176470589 | 7.936507936507936 | 7.352941176470589
NT5C | 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) | 12 | 211.417 | 1 | 1 | 12 | 199.583 | 1 | 1 | 171 | 0 | 195 | 6.153846153846154 | 100 | 50
MazG | MazG nucleotide pyrophosphohydrolase domain | 17 | 150.176 | 1 | 1 | 15 | 122.867 | 1 | 1 | 1794 | 0 | 1826 | 0.8214676889375685 | 88.23529411764706 | 46.875
BC10 | Bladder cancer-related protein BC10 | 43 | 86.279 | 1 | 1 | 17 | 86.353 | 1 | 1 | 31 | 0 | 91 | 18.68131868131868 | 39.53488372093023 | 28.33333333333333
CbiA | CobQ/CobB/MinD/ParA nucleotide binding domain | 4 | 186.25 | 1 | 1 | 17 | 281.059 | 1 | 1 | 10222 | 0 | 10243 | 0.1659670018549253 | 425 | 80.95238095238095
Borrelia_orfX | Orf-X protein | 19 | 158.105 | 1 | 1 | 18 | 166.611 | 1 | 1 | 0 | 0 | 37 | 48.64864864864865 | 94.73684210526315 | 48.64864864864865
Cpn10 | [NAME] 10 Kd subunit | 95 | 91.811 | 1 | 1 | 18 | 110.611 | 1 | 1 | 2001 | 0 | 2114 | 0.8514664143803218 | 18.94736842105263 | 15.92920353982301
Salp15 | [NAME] protein of 15kDa inhibits CD4+ T cell activation | 63 | 127.667 | 1 | 1 | 21 | 157 | 1 | 1 | 0 | 0 | 84 | 25 | 33.33333333333333 | 25
DUF3168 | Protein of unknown function (DUF3168) | 6 | 120.833 | 1 | 1 | 27 | 120.889 | 1 | 1 | 118 | 0 | 151 | 17.88079470198675 | 450 | 81.81818181818183
VRR_NUC | VRR-NUC domain | 10 | 864.9 | 1 | 1 | 46 | 123.565 | 1 | 1 | 394 | 0 | 450 | 10.22222222222222 | 460 | 82.14285714285714
RIP | Ribosome inactivating protein | 3 | 459.333 | 1 | 1 | 47 | 317.894 | 1 | 1 | 173 | 0 | 223 | 21.0762331838565 | 1566.666666666667 | 94
IL10 | Interleukin 10 | 131 | 143.969 | 1 | 1 | 63 | 158 | 1 | 1 | 0 | 0 | 194 | 32.47422680412371 | 48.09160305343512 | 32.47422680412371
SSB | Single-strand binding protein family | 54 | 149.426 | 1 | 1 | 72 | 147.472 | 1 | 1 | 3026 | 0 | 3152 | 2.284263959390863 | 133.3333333333333 | 57.14285714285714
AIG2 | AIG2-like family | 61 | 164.607 | 1 | 1 | 4 | 139.25 | 1 | 1 | 805 | 1 | 870 | 0.4597701149425287 | 6.557377049180328 | 6.153846153846154
Hydrolase_4 | Putative lysophospholipase | 35 | 285.257 | 1 | 1 | 25 | 200.16 | 1 | 1 | 1574 | 1 | 1634 | 1.529987760097919 | 71.42857142857143 | 41.66666666666667
MMTV_SAg | Mouse mammary tumour virus superantigen | 24 | 259.5 | 1 | 1 | 63 | 236.302 | 1 | 1 | 0 | 1 | 87 | 72.41379310344827 | 262.5 | 72.41379310344827
Late_protein_L1 | L1 (late) protein | 3 | 247 | 1 | 1 | 2219 | 182.898 | 1 | 1 | 0 | 1 | 2222 | 99.86498649864987 | 73966.66666666666 | 99.86498649864987
Profilin | Profilin | 110 | 131.673 | 1 | 1 | 25 | 132.84 | 1 | 1 | 63 | 2 | 198 | 12.62626262626263 | 22.72727272727273 | 18.51851851851852
Tenui_N | Tenuivirus/Phlebovirus nucleocapsid protein | 5 | 189.8 | 1 | 1 | 228 | 260.439 | 1 | 1 | 0 | 3 | 233 | 97.85407725321889 | 4560 | 97.85407725321889
Pox_A32 | Poxvirus A32 protein | 10 | 314.1 | 1 | 1 | 91 | 277.231 | 1 | 1 | 2 | 6 | 103 | 88.3495145631068 | 910 | 90.0990099009901
Ferritin | Ferritin-like domain | 485 | 180.377 | 1.002 | 1 | 2 | 171 | 1 | 1 | 2978 | 0 | 3465 | 0.05772005772005772 | 0.4123711340206186 | 0.4106776180698152
NGF | Nerve growth factor family | 1668 | 209.826 | 1.002 | 1.001 | 6 | 170.667 | 1 | 1 | 0 | 2 | 1674 | 0.3584229390681004 | 0.3597122302158274 | 0.3584229390681004
zf-Tim10_DDP | Tim10/DDP family zinc finger | 253 | 100.091 | 1.004 | 1.004 | 1 | 352 | 1 | 1 | 229 | 0 | 483 | 0.2070393374741201 | 0.3952569169960474 | 0.3937007874015748
PNP_UDP_1 | Phosphorylase superfamily | 238 | 306.244 | 1.004 | 1 | 3 | 272.333 | 1 | 1 | 4706 | 0 | 4947 | 0.06064281382656155 | 1.260504201680672 | 1.244813278008299
SIR2 | Sir2 family | 274 | 403.828 | 1.004 | 1.004 | 5 | 251.8 | 1 | 1 | 1482 | 0 | 1761 | 0.2839295854628052 | 1.824817518248175 | 1.792114695340502
LACT | [NAME]:cholesterol acyltransferase | 204 | 263.01 | 1.005 | 1 | 2 | 378 | 1 | 1 | 158 | 0 | 364 | 0.5494505494505495 | 0.9803921568627451 | 0.9708737864077669
CBFD_NFYB_HMF | Histone-like transcription factor (CBF/NF-Y) and archaeal histone | 315 | 209.46 | 1.006 | 1.006 | 1 | 176 | 1 | 1 | 370 | 0 | 686 | 0.1457725947521866 | 0.3174603174603174 | 0.3164556962025317
Glyco_transf_11 | Glycosyl transferase family 11 | 151 | 340.503 | 1.007 | 1.007 | 1 | 264 | 1 | 1 | 132 | 0 | 284 | 0.3521126760563381 | 0.6622516556291391 | 0.6578947368421052
ABC1 | ABC1 family | 120 | 535.983 | 1.008 | 1.008 | 7 | 455.571 | 1 | 1 | 1628 | 0 | 1755 | 0.3988603988603989 | 5.833333333333333 | 5.511811023622047
Lipase_3 | Lipase (class 3) | 116 | 518.052 | 1.009 | 1.009 | 8 | 272.5 | 1 | 1 | 856 | 1 | 980 | 0.8163265306122449 | 6.896551724137931 | 6.451612903225806
GSHPx | Glutathione peroxidase | 303 | 173.62 | 1.01 | 1.01 | 4 | 204.5 | 1 | 1 | 1145 | 2 | 1452 | 0.2754820936639119 | 1.32013201320132 | 1.302931596091205
TFIID-18kDa | Transcription initiation factor IID, 18kD subunit | 89 | 226.573 | 1.011 | 1.011 | 2 | 64 | 1 | 1 | 117 | 0 | 208 | 0.9615384615384616 | 2.247191011235955 | 2.197802197802198
Pyridoxal_deC | Pyridoxal-dependent decarboxylase conserved domain | 1403 | 350.853 | 1.011 | 1.001 | 6 | 364.167 | 1 | 1 | 1478 | 0 | 2887 | 0.2078281953585036 | 0.4276550249465432 | 0.42583392476934
SprT-like | SprT-like family | 88 | 618.33 | 1.011 | 1.011 | 21 | 172.048 | 1 | 1 | 679 | 0 | 788 | 2.66497461928934 | 23.86363636363636 | 19.26605504587156
3Beta_HSD | 3-beta hydroxysteroid dehydrogenase/isomerase family | 177 | 332.537 | 1.011 | 1 | 68 | 256.015 | 1 | 1 | 380 | 5 | 625 | 10.88 | 38.4180790960452 | 27.75510204081633
MIP | Major intrinsic protein | 556 | 258.897 | 1.013 | 1.005 | 2 | 270 | 1 | 1 | 1925 | 0 | 2483 | 0.08054772452678212 | 0.3597122302158274 | 0.3584229390681004
Transaldolase | Transaldolase | 61 | 281.049 | 1.016 | 1.016 | 5 | 221 | 1 | 1 | 1999 | 0 | 2065 | 0.2421307506053269 | 8.19672131147541 | 7.575757575757576
CBAH | Linear amide C-N hydrolases, choloylglycine hydrolase family | 60 | 334.083 | 1.017 | 1 | 6 | 278.833 | 1 | 1 | 641 | 0 | 707 | 0.8486562942008486 | 10 | 9.090909090909092
HSP70 | Hsp70 protein | 1524 | 481.572 | 1.017 | 1.005 | 296 | 304.307 | 1 | 1 | 4866 | 0 | 6686 | 4.427161232425965 | 19.42257217847769 | 16.26373626373626
dNK | Deoxynucleoside kinase | 181 | 281.436 | 1.017 | 1.017 | 39 | 214.462 | 1 | 1 | 621 | 4 | 841 | 4.637336504161712 | 21.54696132596685 | 17.72727272727273
Phospholip_A2_1 | Phospholipase A2 | 832 | 145.596 | 1.019 | 1.005 | 1 | 191 | 1 | 1 | 32 | 0 | 865 | 0.115606936416185 | 0.1201923076923077 | 0.1200480192076831
Pro_dh | Proline dehydrogenase | 54 | 491.259 | 1.019 | 1 | 1 | 253 | 1 | 1 | 1011 | 0 | 1066 | 0.09380863039399624 | 1.851851851851852 | 1.818181818181818
SHMT | Serine hydroxymethyltransferase | 94 | 429.202 | 1.021 | 1 | 3 | 405.667 | 1 | 1 | 1810 | 0 | 1907 | 0.1573151546932355 | 3.191489361702128 | 3.092783505154639
CYTH | CYTH domain | 47 | 200.957 | 1.021 | 1.021 | 4 | 195.25 | 1 | 1 | 1107 | 0 | 1158 | 0.3454231433506045 | 8.51063829787234 | 7.84313725490196
Glyco_transf_6 | Glycosyltransferase family 6 | 314 | 241.761 | 1.022 | 1.006 | 1 | 231 | 1 | 1 | 11 | 0 | 326 | 0.3067484662576687 | 0.3184713375796179 | 0.3174603174603174
Iso_dh | Isocitrate/isopropylmalate dehydrogenase | 418 | 345.866 | 1.022 | 1.017 | 1 | 54 | 1 | 1 | 3503 | 0 | 3922 | 0.02549719530851606 | 0.2392344497607655 | 0.2386634844868735
Phosphorylase | Carbohydrate phosphorylase | 129 | 717.915 | 1.023 | 1.023 | 2 | 102.5 | 1 | 1 | 1284 | 0 | 1415 | 0.1413427561837456 | 1.550387596899225 | 1.526717557251908
DNA_primase_lrg | Eukaryotic and archaeal DNA primase, large subunit | 43 | 481.837 | 1.023 | 1 | 1 | 225 | 1 | 1 | 61 | 1 | 105 | 0.9523809523809524 | 2.325581395348837 | 2.272727272727273
PIG-L | GlcNAc-PI de-N-acetylase | 41 | 286.171 | 1.024 | 1 | 1 | 225 | 1 | 1 | 1327 | 0 | 1369 | 0.07304601899196494 | 2.439024390243902 | 2.380952380952381
TspO_MBR | TspO/[NAME] family | 84 | 160.667 | 1.024 | 1 | 4 | 163.25 | 1 | 1 | 427 | 2 | 515 | 0.7766990291262136 | 4.761904761904762 | 4.545454545454546
EI24 | Etoposide-induced protein 2.4 (EI24) | 40 | 364.65 | 1.025 | 1 | 1 | 262 | 1 | 1 | 7 | 0 | 48 | 2.083333333333333 | 2.5 | 2.439024390243902
UPF0005 | Uncharacterised protein family UPF0005 | 324 | 275.321 | 1.025 | 1.009 | 31 | 223.419 | 1 | 1 | 1232 | 2 | 1587 | 1.953371140516698 | 9.5679012345679 | 8.732394366197182
Methyltransf_15 | RNA cap guanine-N2 methyltransferase | 39 | 548.744 | 1.026 | 1.026 | 1 | 256 | 1 | 1 | 84 | 0 | 124 | 0.8064516129032258 | 2.564102564102564 | 2.5
[NAME] | Phosphate transporter family | 76 | 549.868 | 1.026 | 1 | 1 | 534 | 1 | 1 | 1341 | 0 | 1418 | 0.07052186177715092 | 1.31578947368421 | 1.298701298701299
Acyl_transf_3 | Acyltransferase family | 457 | 675.28 | 1.026 | 1.015 | 8 | 427.625 | 1 | 1 | 3721 | 0 | 4186 | 0.1911132345914955 | 1.75054704595186 | 1.720430107526882
[NAME] | [NAME] | 328 | 173.247 | 1.027 | 1.021 | 1 | 117 | 1 | 1 | 243 | 0 | 572 | 0.1748251748251748 | 0.3048780487804878 | 0.303951367781155
Histone | Core histone H2A/H2B/H3/H4 | 6932 | 119.843 | 1.027 | 1.025 | 4 | 387 | 1 | 1 | 866 | 0 | 7802 | 0.05126890540886952 | 0.05770340450086555 | 0.05767012687427912
ELO | GNS1/SUR4 family | 544 | 276.162 | 1.028 | 1.002 | 7 | 252 | 1 | 1 | 171 | 2 | 722 | 0.9695290858725761 | 1.286764705882353 | 1.270417422867514
Rhabdo_ncap | Rhabdovirus nucleocapsid protein | 36 | 357.75 | 1.028 | 1 | 5141 | 199.595 | 1 | 1 | 0 | 29 | 5177 | 99.304616573305 | 14280.55555555555 | 99.304616573305
DUF159 | Uncharacterised ACR, COG2135 | 35 | 318.086 | 1.029 | 1 | 6 | 225.333 | 1 | 1 | 782 | 0 | 823 | 0.7290400972053462 | 17.14285714285714 | 14.63414634146341
polyprenyl_synt | Polyprenyl synthetase | 174 | 359.052 | 1.029 | 1.017 | 7 | 318 | 1 | 1 | 3329 | 0 | 3510 | 0.1994301994301994 | 4.022988505747127 | 3.867403314917127
DUF1308 | Protein of unknown function (DUF1308) | 33 | 447.727 | 1.03 | 1.03 | 1 | 340 | 1 | 1 | 40 | 0 | 74 | 1.351351351351351 | 3.03030303030303 | 2.941176470588235
bZIP_2 | Basic region leucine zipper | 532 | 305.192 | 1.03 | 1.023 | 3 | 190.333 | 1 | 1 | 174 | 0 | 709 | 0.4231311706629055 | 0.5639097744360901 | 0.5607476635514018
PAP2 | PAP2 superfamily | 483 | 318.337 | 1.031 | 1.029 | 13 | 161.231 | 1 | 1 | 4211 | 0 | 4707 | 0.2761844062035266 | 2.691511387163561 | 2.620967741935484
Adenylsucc_synt | Adenylosuccinate synthetase | 62 | 421.194 | 1.032 | 1 | 7 | 427.857 | 1 | 1 | 1499 | 0 | 1568 | 0.4464285714285714 | 11.29032258064516 | 10.14492753623188
PBP | Phosphatidylethanolamine-binding protein | 243 | 241.267 | 1.033 | 1.029 | 1 | 143 | 1 | 1 | 1014 | 0 | 1258 | 0.0794912559618442 | 0.411522633744856 | 0.4098360655737705
IF4E | Eukaryotic initiation factor 4E | 267 | 229.367 | 1.034 | 1.019 | 1 | 272 | 1 | 1 | 153 | 0 | 421 | 0.2375296912114014 | 0.3745318352059925 | 0.3731343283582089
Acyltransferase | Acyltransferase | 533 | 420.229 | 1.034 | 1.024 | 3 | 342 | 1 | 1 | 4897 | 0 | 5433 | 0.05521811154058532 | 0.5628517823639775 | 0.5597014925373134
Glyco_hydro_16 | Glycosyl hydrolases family 16 | 290 | 384.248 | 1.034 | 1.024 | 6 | 336.167 | 1 | 1 | 1044 | 0 | 1340 | 0.4477611940298508 | 2.068965517241379 | 2.027027027027027
Cupin_4 | Cupin superfamily protein | 142 | 435.134 | 1.035 | 1.035 | 2 | 420 | 1 | 1 | 571 | 0 | 715 | 0.2797202797202797 | 1.408450704225352 | 1.388888888888889
D123 | D123 | 28 | 310.643 | 1.036 | 1 | 1 | 323 | 1 | 1 | 64 | 0 | 93 | 1.075268817204301 | 3.571428571428571 | 3.448275862068965
HpcH_HpaI | HpcH/HpaI aldolase/citrate lyase family | 28 | 320.393 | 1.036 | 1 | 1 | 248 | 1 | 1 | 1977 | 0 | 2006 | 0.04985044865403788 | 3.571428571428571 | 3.448275862068965
Innexin | Innexin | 330 | 382.564 | 1.036 | 1.003 | 23 | 352.783 | 1 | 1 | 0 | 1 | 353 | 6.515580736543909 | 6.969696969696971 | 6.515580736543909
PRP38 | PRP38 family | 80 | 330.512 | 1.038 | 1.038 | 2 | 190 | 1 | 1 | 59 | 0 | 141 | 1.418439716312057 | 2.5 | 2.439024390243902
PTS_2-RNA | RNA 2'-phosphotransferase, Tpt1 / KptA family | 26 | 237.846 | 1.038 | 1.038 | 3 | 185 | 1 | 1 | 230 | 0 | 259 | 1.158301158301158 | 11.53846153846154 | 10.3448275862069
CD20 | CD20-like family | 285 | 295.382 | 1.039 | 1.028 | 2 | 243 | 1 | 1 | 2 | 0 | 289 | 0.6920415224913495 | 0.7017543859649122 | 0.6968641114982579
Srg | [NAME] family chemoreceptor | 125 | 307.056 | 1.04 | 1.024 | 1 | 325 | 1 | 1 | 0 | 0 | 126 | 0.7936507936507936 | 0.8 | 0.7936507936507936
UDPGT | UDP-glucoronosyl and UDP-glucosyl transferase | 1163 | 480.804 | 1.04 | 1.009 | 72 | 485.667 | 1 | 1 | 735 | 3 | 1970 | 3.654822335025381 | 6.190885640584694 | 5.82995951417004
Tmemb_185A | Transmembrane Fragile-X-F protein | 93 | 229.753 | 1.043 | 1.011 | 2 | 80.5 | 1 | 1 | 4 | 0 | 99 | 2.02020202020202 | 2.150537634408602 | 2.105263157894737
Pep_deformylase | Polypeptide deformylase | 45 | 215.244 | 1.044 | 1 | 2 | 137 | 1 | 1 | 2292 | 0 | 2339 | 0.08550662676357418 | 4.444444444444445 | 4.25531914893617
Kua-UEV1_localn | Kua-ubiquitin conjugating enzyme hybrid localisation domain | 43 | 272.093 | 1.047 | 1.047 | 1 | 200 | 1 | 1 | 10 | 0 | 54 | 1.851851851851852 | 2.325581395348837 | 2.272727272727273
Rad60-SLD | Ubiquitin-2 like Rad60 SUMO-like | 172 | 170.797 | 1.047 | 1.035 | 2 | 85 | 1 | 1 | 112 | 2 | 286 | 0.6993006993006993 | 1.162790697674419 | 1.149425287356322
RmlD_sub_bind | RmlD substrate binding domain | 21 | 321.619 | 1.048 | 1.048 | 1 | 289 | 1 | 1 | 1496 | 0 | 1518 | 0.06587615283267458 | 4.761904761904762 | 4.545454545454546
ERCC4 | ERCC4 domain | 96 | 581.354 | 1.052 | 1.031 | 1 | 179 | 1 | 1 | 192 | 0 | 289 | 0.3460207612456748 | 1.041666666666667 | 1.030927835051546
PRK | Phosphoribulokinase / Uridine kinase family | 116 | 361.095 | 1.052 | 1.034 | 1 | 210 | 1 | 1 | 2250 | 0 | 2367 | 0.04224757076468103 | 0.8620689655172413 | 0.8547008547008548
SSF | Sodium:solute symporter family | 590 | 531.397 | 1.054 | 1.01 | 2 | 507 | 1 | 1 | 3546 | 0 | 4138 | 0.04833252779120348 | 0.3389830508474576 | 0.3378378378378378
Ribosomal_L12 | Ribosomal protein L7/L12 C-terminal domain | 54 | 179.185 | 1.056 | 1.019 | 2 | 146.5 | 1 | 1 | 1569 | 0 | 1625 | 0.1230769230769231 | 3.703703703703703 | 3.571428571428571
FR47 | FR47-like protein | 123 | 287.333 | 1.057 | 1.041 | 1 | 149 | 1 | 1 | 402 | 0 | 526 | 0.1901140684410646 | 0.8130081300813009 | 0.8064516129032258
p450 | Cytochrome P450 | 5440 | 413.479 | 1.059 | 1.009 | 2 | 588.5 | 1 | 1 | 6739 | 0 | 12181 | 0.01641901321730564 | 0.03676470588235294 | 0.03675119441381845
dCMP_cyt_deam_1 | Cytidine and deoxycytidylate deaminase zinc-binding region | 196 | 220.143 | 1.061 | 1.005 | 48 | 155.146 | 1 | 1 | 5177 | 0 | 5421 | 0.8854454897620365 | 24.48979591836735 | 19.67213114754098
Sulfotransfer_2 | Sulfotransferase family | 439 | 344.74 | 1.062 | 1.014 | 1 | 285 | 1 | 1 | 415 | 0 | 855 | 0.1169590643274854 | 0.2277904328018223 | 0.2272727272727273
PhyH | Phytanoyl-CoA dioxygenase (PhyH) | 116 | 317.759 | 1.069 | 1.043 | 1 | 257 | 1 | 1 | 1133 | 0 | 1250 | 0.08 | 0.8620689655172413 | 0.8547008547008548
Na_sulph_symp | Sodium:sulfate symporter transmembrane region | 181 | 516.762 | 1.077 | 1.039 | 1 | 424 | 1 | 1 | 1342 | 0 | 1524 | 0.06561679790026247 | 0.5524861878453038 | 0.5494505494505495
Peptidase_C48 | Ulp1 protease family, C-terminal catalytic domain | 271 | 504.694 | 1.077 | 1.044 | 12 | 298.333 | 1 | 1 | 277 | 0 | 560 | 2.142857142857143 | 4.428044280442804 | 4.240282685512367
DUF265 | Protein of unknown function, DUF265 | 37 | 239.324 | 1.081 | 1.081 | 1 | 443 | 1 | 1 | 52 | 0 | 90 | 1.111111111111111 | 2.702702702702703 | 2.631578947368421
zf-LITAF-like | LITAF-like zinc ribbon domain | 292 | 154.774 | 1.082 | 1.058 | 6 | 90.667 | 1 | 1 | 25 | 0 | 323 | 1.857585139318885 | 2.054794520547945 | 2.013422818791946
MTP18 | Mitochondrial 18 KDa protein (MTP18) | 36 | 164.806 | 1.083 | 1 | 1 | 187 | 1 | 1 | 45 | 0 | 82 | 1.219512195121951 | 2.777777777777778 | 2.702702702702703
adh_short | short chain dehydrogenase | 3225 | 287.494 | 1.085 | 1.07 | 3 | 282 | 1 | 1 | 33810 | 0 | 37038 | 0.008099789405475457 | 0.09302325581395349 | 0.09293680297397769
Xan_ur_permease | Permease family | 100 | 504.54 | 1.09 | 1.02 | 3 | 409.667 | 1 | 1 | 4223 | 0 | 4326 | 0.06934812760055478 | 3 | 2.912621359223301
PARG_cat | Poly (ADP-ribose) glycohydrolase (PARG) | 55 | 613.418 | 1.091 | 1.018 | 16 | 527.188 | 1 | 1 | 8 | 0 | 79 | 20.25316455696203 | 29.09090909090909 | 22.53521126760564
MTS | Methyltransferase small domain | 172 | 283.099 | 1.093 | 1.093 | 6 | 654.333 | 1 | 1 | 4343 | 0 | 4521 | 0.13271400132714 | 3.488372093023256 | 3.370786516853932
FGE-sulfatase | Formylglycine-generating sulfatase enzyme | 74 | 330.486 | 1.095 | 1.014 | 3 | 310.667 | 1 | 1 | 1688 | 0 | 1765 | 0.169971671388102 | 4.054054054054054 | 3.896103896103896
G_glu_transpept | Gamma-glutamyltranspeptidase | 230 | 491.104 | 1.096 | 1.035 | 1 | 438 | 1 | 1 | 1551 | 0 | 1782 | 0.05611672278338946 | 0.4347826086956522 | 0.4329004329004329
Glyco_transf_29 | Glycosyltransferase family 29 (sialyltransferase) | 733 | 352.443 | 1.1 | 1.046 | 8 | 306 | 1 | 1 | 28 | 0 | 769 | 1.040312093628089 | 1.091405184174625 | 1.079622132253711
7tm_1 | 7 transmembrane receptor (rhodopsin family) | 22910 | 293.432 | 1.106 | 1.083 | 225 | 355.631 | 1 | 1 | 4 | 4 | 23139 | 0.9723842862699339 | 0.9821038847664776 | 0.9725524097687486
MCM | MCM2/3/5 family | 407 | 682.951 | 1.108 | 1.093 | 1 | 704 | 1 | 1 | 394 | 0 | 802 | 0.1246882793017456 | 0.2457002457002457 | 0.2450980392156863
PNK3P | Polynucleotide kinase 3 phosphatase | 37 | 489.135 | 1.108 | 1.108 | 19 | 317.421 | 1 | 1 | 558 | 0 | 614 | 3.094462540716612 | 51.35135135135135 | 33.92857142857143
7TM_GPCR_Srv | Serpentine type 7TM GPCR chemoreceptor Srv | 64 | 333.531 | 1.109 | 1.016 | 1 | 954 | 1 | 1 | 0 | 0 | 65 | 1.538461538461539 | 1.5625 | 1.538461538461539
PLAC8 | PLAC8 family | 73 | 177.014 | 1.11 | 1.082 | 1 | 122 | 1 | 1 | 69 | 0 | 143 | 0.6993006993006993 | 1.36986301369863 | 1.351351351351351
MFS_1 | Major Facilitator Superfamily | 2909 | 501.055 | 1.11 | 1.042 | 2 | 526.5 | 1 | 1 | 47388 | 0 | 50299 | 0.00397622219129605 | 0.06875214850464077 | 0.06870491240123669
H_lectin | H-type lectin domain | 35 | 293.257 | 1.114 | 1.086 | 1 | 272 | 1 | 1 | 72 | 0 | 108 | 0.9259259259259258 | 2.857142857142857 | 2.777777777777778
COesterase | Carboxylesterase | 2085 | 520.66 | 1.115 | 1.044 | 4 | 631 | 1 | 1 | 1140 | 0 | 3229 | 0.1238773614122019 | 0.1918465227817746 | 0.1914791766395404
Aa_trans | Transmembrane amino acid transporter protein | 610 | 452.744 | 1.12 | 1.01 | 6 | 378.667 | 1 | 1 | 595 | 0 | 1211 | 0.495458298926507 | 0.9836065573770493 | 0.974025974025974
Glyco_transf_8 | Glycosyl transferase family 8 | 251 | 507.924 | 1.12 | 1.112 | 36 | 269.972 | 1 | 1 | 970 | 3 | 1257 | 2.863961813842482 | 14.34262948207171 | 12.54355400696864
[NAME] | Protein of unknown function, DUF258 | 8 | 185.625 | 1.125 | 1.125 | 1 | 74 | 1 | 1 | 1549 | 0 | 1558 | 0.06418485237483953 | 12.5 | 11.11111111111111
Rhomboid | Rhomboid family | 246 | 468.549 | 1.126 | 1.114 | 1 | 171 | 1 | 1 | 2023 | 0 | 2270 | 0.04405286343612335 | 0.4065040650406505 | 0.4048582995951417
Nucleoside_tran | Nucleoside transporter | 149 | 447.893 | 1.128 | 1.013 | 2 | 502.5 | 1 | 1 | 55 | 0 | 206 | 0.9708737864077669 | 1.342281879194631 | 1.324503311258278
PfkB | pfkB family carbohydrate kinase | 270 | 342.867 | 1.13 | 1.081 | 1 | 252 | 1 | 1 | 7308 | 0 | 7579 | 0.01319435281699433 | 0.3703703703703704 | 0.3690036900369004
MCLC | Mid-1-related chloride channel (MCLC) | 15 | 449.333 | 1.133 | 1 | 1 | 316 | 1 | 1 | 0 | 0 | 16 | 6.25 | 6.666666666666667 | 6.25
Sulfotransfer_1 | Sulfotransferase domain | 906 | 364.141 | 1.136 | 1.094 | 1 | 304 | 1 | 1 | 955 | 0 | 1862 | 0.05370569280343716 | 0.1103752759381898 | 0.1102535832414553
SUI1 | Translation initiation factor SUI1 | 195 | 225.272 | 1.138 | 1.128 | 1 | 106 | 1 | 1 | 579 | 0 | 775 | 0.1290322580645161 | 0.5128205128205128 | 0.5102040816326531
DUF833 | Protein of unknown function (DUF833) | 50 | 256.44 | 1.14 | 1 | 2 | 274 | 1 | 1 | 284 | 2 | 336 | 0.5952380952380952 | 4 | 3.846153846153846
Cpn60_TCP1 | TCP-1/cpn60 chaperonin family | 867 | 475.721 | 1.143 | 1.081 | 1 | 558 | 1 | 1 | 10248 | 0 | 11116 | 0.008996041741633681 | 0.1153402537485582 | 0.1152073732718894
AOX | Alternative oxidase | 7 | 170.714 | 1.143 | 1 | 2 | 136 | 1 | 1 | 141 | 0 | 150 | 1.333333333333333 | 28.57142857142857 | 22.22222222222222
Acetyltransf_1 | Acetyltransferase (GNAT) family | 962 | 267.081 | 1.154 | 1.143 | 24 | 162.375 | 1 | 1 | 32317 | 0 | 33303 | 0.07206557967750653 | 2.494802494802495 | 2.434077079107505
FA_hydroxylase | Fatty acid hydroxylase superfamily | 173 | 314.277 | 1.156 | 1.15 | 3 | 286.667 | 1 | 1 | 1438 | 0 | 1614 | 0.1858736059479554 | 1.734104046242774 | 1.704545454545454
[NAME] | [NAME] complex protein 1 (SCP-1) | 12 | 709.333 | 1.167 | 1 | 2 | 262 | 1 | 1 | 0 | 0 | 14 | 14.28571428571428 | 16.66666666666666 | 14.28571428571428
Rad52_Rad22 | Rad52/22 family double-strand break repair protein | 36 | 311.083 | 1.167 | 1.139 | 12 | 235.167 | 1 | 1 | 134 | 0 | 182 | 6.593406593406594 | 33.33333333333333 | 25
HD | HD domain | 100 | 332.76 | 1.17 | 1.17 | 5 | 274.6 | 1 | 1 | 10715 | 0 | 10820 | 0.04621072088724584 | 5 | 4.761904761904762
Lipase | Lipase | 975 | 366.315 | 1.17 | 1.158 | 8 | 589.5 | 1 | 1 | 4 | 1 | 987 | 0.8105369807497468 | 0.8205128205128205 | 0.8138351983723295
Carb_anhydrase | Eukaryotic-type carbonic anhydrase | 641 | 330.758 | 1.173 | 1.092 | 39 | 303.026 | 1 | 1 | 246 | 2 | 926 | 4.211663066954643 | 6.084243369734789 | 5.735294117647059
Fork_head | Fork head domain | 1501 | 394.718 | 1.175 | 1.168 | 2 | 391 | 1 | 1 | 229 | 1 | 1732 | 0.115473441108545 | 0.1332445036642239 | 0.1330671989354624
DUF672 | Protein of unknown function (DUF672) | 17 | 307.294 | 1.176 | 1.059 | 1 | 646 | 1 | 1 | 7 | 0 | 25 | 4 | 5.88235294117647 | 5.555555555555555
Sod_Cu | Copper/zinc superoxide dismutase (SODC) | 430 | 231.535 | 1.177 | 1.07 | 97 | 144.763 | 1 | 1 | 863 | 6 | 1390 | 6.97841726618705 | 22.55813953488372 | 18.40607210626186
Asp_Arg_Hydrox | Aspartyl/Asparaginyl beta-hydroxylase | 73 | 509.452 | 1.178 | 1.151 | 3 | 218.333 | 1 | 1 | 350 | 0 | 426 | 0.7042253521126761 | 4.10958904109589 | 3.947368421052631
DUF836 | Glutaredoxin-like domain (DUF836) | 21 | 299.714 | 1.19 | 1.19 | 42 | 125.548 | 1 | 1 | 504 | 5 | 567 | 7.407407407407407 | 200 | 66.66666666666666
7TM_GPCR_Srw | Serpentine type 7TM GPCR chemoreceptor Srw | 376 | 381.051 | 1.191 | 1.032 | 1 | 113 | 1 | 1 | 0 | 0 | 377 | 0.2652519893899204 | 0.2659574468085106 | 0.2652519893899204
CN_hydrolase | Carbon-nitrogen hydrolase | 303 | 422.815 | 1.191 | 1.188 | 6 | 297.5 | 1 | 1 | 4776 | 0 | 5085 | 0.1179941002949852 | 1.98019801980198 | 1.941747572815534
HIT | HIT domain | 132 | 198.818 | 1.205 | 1.197 | 6 | 219.167 | 1 | 1 | 2464 | 0 | 2602 | 0.2305918524212144 | 4.545454545454546 | 4.347826086956522
ETX_MTX2 | Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 | 40 | 315.825 | 1.25 | 1.175 | 1 | 286 | 1 | 1 | 72 | 0 | 113 | 0.8849557522123894 | 2.5 | 2.439024390243902
ATG27 | Autophagy-related protein 27 | 4 | 413 | 1.25 | 1.25 | 1 | 90 | 1 | 1 | 66 | 1 | 71 | 1.408450704225352 | 25 | 20
Amino_oxidase | Flavin containing amine oxidoreductase | 436 | 485.583 | 1.257 | 1.154 | 3 | 456.667 | 1 | 1 | 3227 | 0 | 3666 | 0.08183306055646482 | 0.6880733944954129 | 0.683371298405467
Methyltransf_11 | Methyltransferase domain | 541 | 362.305 | 1.262 | 1.237 | 9 | 203.222 | 1 | 1 | 14906 | 2 | 15456 | 0.05822981366459627 | 1.66358595194085 | 1.636363636363636
[NAME] | [NAME] domain | 474 | 212.39 | 1.264 | 1.08 | 44 | 95.818 | 1 | 1 | 30 | 0 | 548 | 8.02919708029197 | 9.282700421940929 | 8.494208494208493
Bcl-2 | Apoptosis regulator proteins, Bcl-2 family | 311 | 220.614 | 1.267 | 1.244 | 42 | 184.262 | 1 | 1 | 0 | 3 | 353 | 11.89801699716714 | 13.5048231511254 | 11.89801699716714
ERG4_ERG24 | Ergosterol biosynthesis ERG4/ERG24 family | 78 | 480 | 1.269 | 1.154 | 1 | 447 | 1 | 1 | 285 | 0 | 364 | 0.2747252747252747 | 1.282051282051282 | 1.265822784810127
AA_permease | Amino acid permease | 820 | 666.848 | 1.273 | 1.144 | 1 | 419 | 1 | 1 | 11008 | 0 | 11829 | 0.0084537999830924 | 0.1219512195121951 | 0.1218026796589525
Chitin_synth_2 | Chitin synthase | 153 | 1012.876 | 1.275 | 1.255 | 12 | 534.167 | 1 | 1 | 838 | 0 | 1003 | 1.196410767696909 | 7.84313725490196 | 7.272727272727272
Glyoxalase | Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily | 145 | 270.255 | 1.276 | 1.028 | 3 | 123.667 | 1 | 1 | 10879 | 0 | 11027 | 0.02720594903418881 | 2.068965517241379 | 2.027027027027027
Pribosyltran | Phosphoribosyl transferase domain | 363 | 311.094 | 1.284 | 1.27 | 6 | 279.333 | 1 | 1 | 12522 | 0 | 12891 | 0.04654410053525716 | 1.652892561983471 | 1.626016260162602
DNA_binding_1 | 6-O-methylguanine DNA methyltransferase, DNA binding domain | 35 | 179.4 | 1.286 | 1.286 | 1 | 149 | 1 | 1 | 2428 | 0 | 2464 | 0.04058441558441558 | 2.857142857142857 | 2.777777777777778
Retrotrans_gag | [NAME] gag protein | 105 | 529.686 | 1.295 | 1.286 | 1 | 410 | 1 | 1 | 175 | 0 | 281 | 0.3558718861209964 | 0.9523809523809524 | 0.9433962264150944
[NAME] | [NAME] class-V | 278 | 439.158 | 1.299 | 1.227 | 8 | 389.625 | 1 | 1 | 7587 | 0 | 7873 | 0.1016131080909437 | 2.877697841726619 | 2.797202797202797
DPBB_1 | Rare lipoprotein A (RlpA)-like double-psi beta-barrel | 10 | 191.3 | 1.3 | 1.3 | 1 | 120 | 1 | 1 | 1091 | 0 | 1102 | 0.09074410163339383 | 10 | 9.090909090909092
DUF821 | Arabidopsis thaliana protein of unknown function (DUF821) | 73 | 409.452 | 1.315 | 1.301 | 12 | 980.083 | 1 | 1 | 256 | 2 | 341 | 3.519061583577713 | 16.43835616438356 | 14.11764705882353
Endothelin | Endothelin family | 63 | 173.714 | 1.317 | 1 | 2 | 69 | 1 | 1 | 0 | 0 | 65 | 3.076923076923077 | 3.174603174603174 | 3.076923076923077
HSP20 | Hsp20/[NAME] family | 911 | 168.114 | 1.333 | 1.302 | 4 | 149.25 | 1 | 1 | 2431 | 0 | 3346 | 0.1195457262402869 | 0.4390779363336992 | 0.4371584699453552
FtsK_SpoIIIE | FtsK/SpoIIIE family | 3 | 408.667 | 1.333 | 1.333 | 10 | 440.7 | 1 | 1 | 2563 | 0 | 2576 | 0.3881987577639752 | 333.3333333333334 | 76.92307692307693
Lipocalin_2 | [NAME]-like domain | 73 | 259.849 | 1.342 | 1.055 | 2 | 185.5 | 1 | 1 | 516 | 0 | 591 | 0.338409475465313 | 2.73972602739726 | 2.666666666666667
NDK | Nucleoside diphosphate kinase | 326 | 238.991 | 1.344 | 1.147 | 1 | 137 | 1 | 1 | 1322 | 0 | 1649 | 0.06064281382656155 | 0.3067484662576687 | 0.3058103975535168
Homeobox | Homeobox domain | 9806 | 289.419 | 1.345 | 1.269 | 1 | 224 | 1 | 1 | 403 | 0 | 10210 | 0.00979431929480901 | 0.01019783805833163 | 0.01019679820536352
CIDE-N | CIDE-N domain | 137 | 311.102 | 1.358 | 1.358 | 5 | 129.8 | 1 | 1 | 0 | 1 | 142 | 3.52112676056338 | 3.64963503649635 | 3.52112676056338
PGAM | Phosphoglycerate mutase family | 428 | 351.077 | 1.364 | 1.362 | 3 | 391.333 | 1 | 1 | 6438 | 0 | 6869 | 0.04367447954578541 | 0.7009345794392523 | 0.6960556844547563
Pro_isomerase | Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD | 898 | 314.208 | 1.386 | 1.273 | 1 | 234 | 1 | 1 | 2977 | 0 | 3876 | 0.02579979360165119 | 0.111358574610245 | 0.1112347052280311
RF-1 | RF-1 domain | 121 | 256.562 | 1.388 | 1.38 | 7 | 114.857 | 1 | 1 | 3580 | 0 | 3708 | 0.1887810140237325 | 5.785123966942149 | 5.46875
PALP | Pyridoxal-phosphate dependent enzyme | 198 | 421.051 | 1.399 | 1.348 | 2 | 294.5 | 1 | 1 | 10012 | 0 | 10212 | 0.01958480219349784 | 1.01010101010101 | 1
Meth_synt_2 | Cobalamin-independent synthase, Catalytic domain | 5 | 294.6 | 1.4 | 1 | 1 | 101 | 1 | 1 | 1301 | 0 | 1307 | 0.07651109410864575 | 20 | 16.66666666666666
PAPS_reduct | Phosphoadenosine phosphosulfate reductase family | 47 | 344.277 | 1.404 | 1.383 | 13 | 303.462 | 1 | 1 | 2141 | 0 | 2201 | 0.5906406179009541 | 27.65957446808511 | 21.66666666666667
Polyketide_cyc2 | Polyketide cyclase / dehydrase and lipid transport | 7 | 343.429 | 1.429 | 1.286 | 2 | 146 | 1 | 1 | 1713 | 0 | 1722 | 0.116144018583043 | 28.57142857142857 | 22.22222222222222
GDPD | Glycerophosphoryl diester phosphodiesterase family | 181 | 516.646 | 1.431 | 1.409 | 6 | 432.833 | 1 | 1 | 2904 | 0 | 3091 | 0.1941119378841799 | 3.314917127071823 | 3.208556149732621
Proteasome | Proteasome subunit | 1450 | 237.748 | 1.447 | 1.446 | 1 | 192 | 1 | 1 | 2050 | 0 | 3501 | 0.02856326763781777 | 0.06896551724137931 | 0.06891798759476223
IL1 | Interleukin-1 / 18 | 272 | 218.676 | 1.456 | 1.456 | 2 | 164.5 | 1 | 1 | 0 | 0 | 274 | 0.7299270072992701 | 0.7352941176470588 | 0.7299270072992701
TRAM_LAG1_CLN8 | TLC domain | 315 | 328.4 | 1.46 | 1.444 | 14 | 168.643 | 1 | 1 | 207 | 0 | 536 | 2.611940298507462 | 4.444444444444445 | 4.25531914893617
UPAR_LY6 | u-PAR/Ly-6 domain | 318 | 175.11 | 1.475 | 1.299 | 2 | 118.5 | 1 | 1 | 0 | 0 | 320 | 0.625 | 0.628930817610063 | 0.625
Peptidase_C14 | Caspase domain | 618 | 367.49 | 1.49 | 1.322 | 1 | 231 | 1 | 1 | 763 | 0 | 1382 | 0.0723589001447178 | 0.1618122977346279 | 0.1615508885298869
Trypsin | Trypsin | 8390 | 341.018 | 1.497 | 1.292 | 16 | 314.625 | 1 | 1 | 4545 | 0 | 12951 | 0.1235425835842792 | 0.1907032181168057 | 0.1903402331667856
Peptidase_S15 | X-Pro dipeptidyl-peptidase (S15 family) | 6 | 301 | 1.5 | 1.5 | 1 | 257 | 1 | 1 | 1491 | 0 | 1498 | 0.06675567423230974 | 16.66666666666666 | 14.28571428571428
zf-BED | BED zinc finger | 187 | 418.578 | 1.503 | 1.257 | 1 | 974 | 1 | 1 | 34 | 0 | 222 | 0.4504504504504505 | 0.53475935828877 | 0.5319148936170213
Branch | [NAME]/I-Branching enzyme | 183 | 559.689 | 1.519 | 1.508 | 7 | 434.286 | 1 | 1 | 123 | 0 | 313 | 2.236421725239616 | 3.825136612021858 | 3.684210526315789
Mov34 | Mov34/MPN/PAD-1 family | 471 | 474.803 | 1.535 | 1.524 | 7 | 148.429 | 1 | 1 | 499 | 0 | 977 | 0.7164790174002047 | 1.48619957537155 | 1.464435146443515
ENTH | ENTH domain | 143 | 576.42 | 1.538 | 1.294 | 1 | 252 | 1 | 1 | 151 | 1 | 295 | 0.3389830508474576 | 0.6993006993006993 | 0.6944444444444444
PP2C | Protein phosphatase 2C | 531 | 481.879 | 1.542 | 1.25 | 6 | 246.833 | 1 | 1 | 1335 | 1 | 1872 | 0.3205128205128205 | 1.129943502824859 | 1.11731843575419
MADF_DNA_bdg | Alcohol dehydrogenase transcription factor Myb/SANT-like | 866 | 483.763 | 1.565 | 1.279 | 1 | 184 | 1 | 1 | 0 | 1 | 867 | 0.1153402537485582 | 0.115473441108545 | 0.1153402537485582
AT_hook | AT hook motif | 53 | 243.585 | 1.566 | 1.226 | 4 | 129 | 1 | 1 | 90 | 0 | 147 | 2.72108843537415 | 7.547169811320755 | 7.017543859649122
SMC_N | RecF/RecN/SMC N terminal domain | 322 | 903.888 | 1.568 | 1.528 | 8 | 621.625 | 1 | 1 | 4013 | 1 | 4343 | 0.1842044669583237 | 2.484472049689441 | 2.424242424242424
Morph_protein1 | Defects in morphology protein 1, mitochondrial precursor | 7 | 331.429 | 1.571 | 1 | 1 | 310 | 1 | 1 | 59 | 0 | 67 | 1.492537313432836 | 14.28571428571428 | 12.5
PFK | Phosphofructokinase | 148 | 513.865 | 1.574 | 1 | 1 | 282 | 1 | 1 | 1572 | 0 | 1721 | 0.05810575246949447 | 0.6756756756756757 | 0.6711409395973155
CRAL_TRIO | CRAL/TRIO domain | 962 | 381.551 | 1.584 | 1.565 | 1 | 215 | 1 | 1 | 352 | 0 | 1315 | 0.07604562737642585 | 0.103950103950104 | 0.1038421599169263
Evr1_Alr | Erv1 / Alr family | 123 | 461.358 | 1.602 | 1.593 | 40 | 142.05 | 1 | 1 | 114 | 2 | 277 | 14.44043321299639 | 32.52032520325203 | 24.5398773006135
Thioredoxin | Thioredoxin | 1311 | 383.519 | 1.609 | 1.192 | 39 | 130.385 | 1 | 1 | 5790 | 2 | 7140 | 0.5462184873949579 | 2.974828375286041 | 2.888888888888889
[NAME] | Methyltransferase domain | 164 | 501.445 | 1.628 | 1.628 | 1 | 237 | 1 | 1 | 2507 | 0 | 2672 | 0.03742514970059881 | 0.6097560975609756 | 0.6060606060606061
UCH | Ubiquitin carboxyl-terminal hydrolase | 1241 | 855.957 | 1.633 | 1.522 | 9 | 319.222 | 1 | 1 | 995 | 0 | 2245 | 0.4008908685968819 | 0.7252215954875101 | 0.72
DUF814 | Domain of unknown function (DUF814) | 89 | 465.506 | 1.64 | 1.64 | 6 | 113 | 1 | 1 | 705 | 0 | 800 | 0.75 | 6.741573033707865 | 6.315789473684211
Saccharop_dh | Saccharopine dehydrogenase | 100 | 565.48 | 1.66 | 1.65 | 7 | 504.429 | 1 | 1 | 1236 | 0 | 1343 | 0.5212211466865228 | 7 | 6.542056074766355
PQ-loop | PQ loop repeat | 219 | 293.224 | 1.662 | 1.018 | 1 | 97 | 1 | 1 | 617 | 0 | 837 | 0.1194743130227001 | 0.45662100456621 | 0.4545454545454545
TGF_beta | Transforming growth factor beta like domain | 1382 | 334.005 | 1.684 | 1.672 | 8 | 293.25 | 1 | 1 | 0 | 2 | 1390 | 0.5755395683453237 | 0.5788712011577424 | 0.5755395683453237
TLD | TLD | 240 | 504.158 | 1.688 | 1.596 | 1 | 192 | 1 | 1 | 115 | 0 | 356 | 0.2808988764044944 | 0.4166666666666667 | 0.4149377593360996
Glycos_transf_1 | Glycosyl transferases group 1 | 238 | 612.857 | 1.689 | 1.496 | 35 | 328.543 | 1 | 1 | 15113 | 0 | 15386 | 0.2274795268425842 | 14.70588235294118 | 12.82051282051282
Cupin_2 | Cupin domain | 10 | 415.1 | 1.7 | 1.6 | 6 | 171.667 | 1 | 1 | 7276 | 0 | 7292 | 0.08228195282501372 | 60 | 37.5
Lactamase_B | Metallo-beta-lactamase superfamily | 394 | 451.515 | 1.708 | 1.683 | 9 | 403.556 | 1 | 1 | 14308 | 0 | 14711 | 0.06117870980898647 | 2.284263959390863 | 2.233250620347394
CSD | 'Cold-shock' DNA-binding domain | 278 | 340.993 | 1.716 | 1.083 | 1 | 66 | 1 | 1 | 4423 | 0 | 4702 | 0.02126754572522331 | 0.3597122302158274 | 0.3584229390681004
RHD | Rel homology domain (RHD) | 466 | 627.006 | 1.721 | 1.47 | 1 | 503 | 1 | 1 | 0 | 1 | 467 | 0.2141327623126338 | 0.2145922746781116 | 0.2141327623126338
Abhydrolase_3 | alpha/beta hydrolase fold | 186 | 468.661 | 1.726 | 1.28 | 2 | 306 | 1 | 1 | 4020 | 0 | 4208 | 0.04752851711026616 | 1.075268817204301 | 1.063829787234043
PAM2 | Ataxin-2 C-terminal region | 187 | 475.652 | 1.738 | 1.695 | 1 | 438 | 1 | 1 | 3 | 0 | 191 | 0.5235602094240838 | 0.53475935828877 | 0.5319148936170213
HMG-CoA_red | Hydroxymethylglutaryl-coenzyme A reductase | 74 | 755.122 | 1.743 | 1.743 | 1 | 107 | 1 | 1 | 498 | 0 | 573 | 0.1745200698080279 | 1.351351351351351 | 1.333333333333333
PEP-utilizers | PEP-utilising enzyme, mobile domain | 8 | 650.125 | 1.75 | 1.625 | 1 | 43 | 1 | 1 | 3529 | 0 | 3538 | 0.02826455624646693 | 12.5 | 11.11111111111111
Sigma70_r4_2 | [NAME], region 4 | 4 | 384.5 | 1.75 | 1.75 | 12 | 94.5 | 1 | 1 | 9083 | 0 | 9099 | 0.1318826244642268 | 300 | 75
RVP_2 | Retroviral aspartyl protease | 9 | 769.444 | 1.778 | 1.778 | 1 | 142 | 1 | 1 | 60 | 0 | 70 | 1.428571428571429 | 11.11111111111111 | 10
zf-AN1 | AN1-like Zinc finger | 227 | 283.551 | 1.78 | 1.485 | 4 | 72 | 1 | 1 | 109 | 0 | 340 | 1.176470588235294 | 1.762114537444934 | 1.731601731601732
DUF2075 | Uncharacterized conserved protein (DUF2075) | 32 | 800.406 | 1.781 | 1.781 | 1 | 463 | 1 | 1 | 489 | 0 | 522 | 0.1915708812260536 | 3.125 | 3.03030303030303
Rhodanese | Rhodanese-like domain | 552 | 413.364 | 1.788 | 1.712 | 1 | 84 | 1 | 1 | 7824 | 0 | 8377 | 0.01193744777366599 | 0.1811594202898551 | 0.1808318264014467
AhpC-TSA | AhpC/TSA family | 488 | 215.814 | 1.789 | 1.775 | 1 | 144 | 1 | 1 | 5344 | 0 | 5833 | 0.01714383679067375 | 0.2049180327868853 | 0.2044989775051125
GGDEF | GGDEF domain | 15 | 368.933 | 1.8 | 1.8 | 1 | 156 | 1 | 1 | 16016 | 0 | 16032 | 0.0062375249500998 | 6.666666666666667 | 6.25
Peptidase_S9 | Prolyl oligopeptidase family | 356 | 717.228 | 1.809 | 1.784 | 1 | 294 | 1 | 1 | 3915 | 0 | 4272 | 0.02340823970037453 | 0.2808988764044944 | 0.2801120448179272
Tubulin | Tubulin/FtsZ family, GTPase domain | 1434 | 351.152 | 1.812 | 1.801 | 2 | 336.5 | 1 | 1 | 6946 | 0 | 8382 | 0.02386065378191362 | 0.1394700139470014 | 0.1392757660167131
[NAME] | [NAME] family | 162 | 681.08 | 1.827 | 1.815 | 6 | 279.667 | 1 | 1 | 17 | 0 | 185 | 3.243243243243243 | 3.703703703703703 | 3.571428571428571
TonB_dep_Rec | TonB dependent receptor | 6 | 520.167 | 1.833 | 1.833 | 1 | 176 | 1 | 1 | 11443 | 0 | 11450 | 0.008733624454148471 | 16.66666666666666 | 14.28571428571428
Peptidase_S49 | Peptidase family S49 | 6 | 342.667 | 1.833 | 1.667 | 97 | 170.454 | 1 | 1 | 1653 | 0 | 1756 | 5.523917995444191 | 1616.666666666667 | 94.1747572815534
K_tetra | K+ channel tetramerisation domain | 1009 | 434.689 | 1.835 | 1.737 | 5 | 519.6 | 1 | 1 | 33 | 0 | 1047 | 0.4775549188156638 | 0.4955401387512388 | 0.4930966469428008
Hint | Hint module | 158 | 416.07 | 1.854 | 1.759 | 1 | 1253 | 1 | 1 | 1 | 0 | 160 | 0.625 | 0.6329113924050633 | 0.628930817610063
C1q | C1q domain | 526 | 298.375 | 1.856 | 1.57 | 2 | 519 | 1 | 1 | 148 | 0 | 676 | 0.2958579881656805 | 0.3802281368821293 | 0.3787878787878788
TBP | Transcription factor TFIID (or TATA-binding protein, TBP) | 211 | 318.218 | 1.858 | 1 | 8 | 293.625 | 1 | 1 | 69 | 0 | 288 | 2.777777777777778 | 3.791469194312796 | 3.65296803652968
ASCH | ASCH domain | 36 | 493.444 | 1.861 | 1.861 | 9 | 115 | 1 | 1 | 752 | 0 | 797 | 1.129234629861982 | 25 | 20
Cullin | [NAME] family | 312 | 711.926 | 1.907 | 1.849 | 2 | 228.5 | 1 | 1 | 251 | 0 | 565 | 0.3539823008849557 | 0.641025641025641 | 0.6369426751592357
[NAME] | Patatin-like phospholipase | 267 | 688.873 | 1.91 | 1.363 | 16 | 314.438 | 1 | 1 | 3485 | 1 | 3768 | 0.4246284501061571 | 5.992509363295881 | 5.653710247349824
Gly_transf_sug | Glycosyltransferase sugar-binding region containing DXD motif | 102 | 350.706 | 1.912 | 1.912 | 1 | 251 | 1 | 1 | 587 | 0 | 690 | 0.1449275362318841 | 0.9803921568627451 | 0.9708737864077669
DUF3609 | Protein of unknown function (DUF3609) | 62 | 516.597 | 1.919 | 1.919 | 37 | 644.378 | 1 | 1 | 0 | 4 | 99 | 37.37373737373738 | 59.67741935483871 | 37.37373737373738
Peptidase_M20 | Peptidase family M20/M25/M40 | 249 | 422.815 | 1.92 | 1.92 | 2 | 376 | 1 | 1 | 9161 | 0 | 9412 | 0.02124946876328092 | 0.8032128514056224 | 0.796812749003984
DUF2370 | Protein of unknown function (DUF2370) | 65 | 230.954 | 1.923 | 1.015 | 1 | 85 | 1 | 1 | 62 | 0 | 128 | 0.78125 | 1.538461538461539 | 1.515151515151515
DUF88 | Protein of unknown function DUF88 | 15 | 880.667 | 1.933 | 1.933 | 1 | 251 | 1 | 1 | 947 | 0 | 963 | 0.1038421599169263 | 6.666666666666667 | 6.25
Beta-lactamase | Beta-lactamase | 84 | 611.655 | 1.952 | 1.155 | 41 | 561.439 | 1 | 1 | 6981 | 0 | 7106 | 0.5769772023641992 | 48.80952380952381 | 32.8
DUF699 | Putative ATPase (DUF699) | 43 | 915.465 | 1.953 | 1.93 | 3 | 460 | 1 | 1 | 892 | 0 | 938 | 0.3198294243070363 | 6.976744186046512 | 6.521739130434782
F-box | F-box domain | 1742 | 486.408 | 1.955 | 1.547 | 13 | 224 | 1 | 1 | 978 | 0 | 2733 | 0.4756677643615075 | 0.7462686567164178 | 0.7407407407407408
NifU | NifU-like domain | 51 | 244.843 | 1.961 | 1.961 | 1 | 96 | 1 | 1 | 1144 | 0 | 1196 | 0.08361204013377926 | 1.96078431372549 | 1.923076923076923
APS_kinase | Adenylylsulphate kinase | 67 | 590.985 | 1.97 | 1.955 | 1 | 231 | 1 | 1 | 1123 | 0 | 1191 | 0.08396305625524769 | 1.492537313432836 | 1.470588235294118
PAAD_DAPIN | PAAD/DAPIN/Pyrin domain | 168 | 661.988 | 1.97 | 1.935 | 5 | 123 | 1 | 1 | 0 | 0 | 173 | 2.890173410404624 | 2.976190476190476 | 2.890173410404624
Cyt-b5 | Cytochrome b5-like Heme/Steroid binding domain | 546 | 392.566 | 1.991 | 1.606 | 1 | 124 | 1 | 1 | 1243 | 0 | 1790 | 0.05586592178770949 | 0.1831501831501831 | 0.1828153564899452
Lectin_C | [NAME] domain | 3654 | 366.83 | 1.991 | 1.41 | 16 | 277.25 | 1 | 1 | 43 | 3 | 3713 | 0.4309183948289793 | 0.4378762999452655 | 0.4359673024523161
FHA | FHA domain | 676 | 816.448 | 2 | 1.864 | 1 | 215 | 1 | 1 | 2504 | 0 | 3181 | 0.03143665513989311 | 0.1479289940828402 | 0.1477104874446086
Hydrolase_3 | haloacid dehalogenase-like hydrolase | 10 | 360.7 | 2 | 2 | 2 | 186.5 | 1 | 1 | 5435 | 0 | 5447 | 0.03671745915182669 | 20 | 16.66666666666666
DUF830 | Orthopoxvirus protein of unknown function (DUF830) | 3 | 689.333 | 2 | 2 | 56 | 171.679 | 1 | 1 | 479 | 6 | 538 | 10.4089219330855 | 1866.666666666667 | 94.91525423728814
CENP-B_N | CENP-B N-terminal DNA-binding domain | 148 | 458.703 | 2.014 | 2.007 | 5 | 112.4 | 1 | 1 | 35 | 0 | 188 | 2.659574468085106 | 3.378378378378379 | 3.267973856209151
SDA1 | SDA1 | 36 | 674.917 | 2.028 | 1.889 | 1 | 270 | 1 | 1 | 59 | 0 | 96 | 1.041666666666667 | 2.777777777777778 | 2.702702702702703
Smr | Smr domain | 36 | 806.5 | 2.028 | 2 | 1 | 113 | 1 | 1 | 1609 | 0 | 1646 | 0.06075334143377886 | 2.777777777777778 | 2.702702702702703
Ion_trans_2 | Ion channel | 810 | 522.362 | 2.044 | 1.375 | 18 | 96.444 | 1 | 1 | 1535 | 0 | 2363 | 0.761743546339399 | 2.222222222222222 | 2.173913043478261
Arch_ATPase | Archaeal ATPase | 19 | 825.368 | 2.053 | 1.421 | 2 | 206 | 1 | 1 | 668 | 0 | 689 | 0.2902757619738752 | 10.52631578947368 | 9.523809523809524
Radical_SAM | Radical SAM superfamily | 239 | 463.741 | 2.054 | 2.05 | 10 | 279.3 | 1 | 1 | 20622 | 0 | 20871 | 0.04791337262229888 | 4.184100418410042 | 4.016064257028113
zf-MYND | MYND finger | 740 | 557.164 | 2.074 | 1.892 | 4 | 202.5 | 1 | 1 | 296 | 0 | 1040 | 0.3846153846153846 | 0.5405405405405406 | 0.5376344086021506
Polysacc_deac_1 | Polysaccharide deacetylase | 77 | 878.182 | 2.078 | 1.896 | 3 | 381.667 | 1 | 1 | 4959 | 0 | 5039 | 0.05953562214725144 | 3.896103896103896 | 3.75
Pyr_redox_2 | Pyridine nucleotide-disulphide oxidoreductase | 585 | 605.694 | 2.118 | 2.115 | 1 | 124 | 1 | 1 | 18963 | 0 | 19549 | 0.005115351168857743 | 0.1709401709401709 | 0.1706484641638225
[NAME] | [NAME] family | 584 | 669.577 | 2.128 | 2.08 | 1 | 592 | 1 | 1 | 1236 | 0 | 1821 | 0.05491488193300385 | 0.1712328767123288 | 0.1709401709401709
IMPDH | IMP dehydrogenase / GMP reductase domain | 122 | 396.525 | 2.139 | 1.541 | 2 | 347 | 1 | 1 | 2068 | 0 | 2192 | 0.09124087591240876 | 1.639344262295082 | 1.612903225806452
IBR | IBR domain | 363 | 622.006 | 2.149 | 1.419 | 1 | 990 | 1 | 1 | 294 | 0 | 658 | 0.1519756838905775 | 0.2754820936639119 | 0.2747252747252747
DUF2233 | Predicted periplasmic protein (DUF2233) | 16 | 462.75 | 2.188 | 1.75 | 2 | 600 | 1 | 1 | 426 | 0 | 444 | 0.4504504504504505 | 12.5 | 11.11111111111111
MATH | MATH domain | 553 | 480.675 | 2.231 | 1.888 | 3 | 266.667 | 1 | 1 | 67 | 1 | 623 | 0.4815409309791332 | 0.5424954792043399 | 0.539568345323741
SET | SET domain | 1149 | 847.218 | 2.235 | 1.987 | 11 | 174.636 | 1 | 1 | 1049 | 0 | 2209 | 0.4979628791308284 | 0.9573542210617928 | 0.9482758620689655
Ricin_B_lectin | Ricin-type beta-trefoil lectin domain | 507 | 610.799 | 2.239 | 1.929 | 3 | 258.667 | 1 | 1 | 655 | 0 | 1165 | 0.2575107296137339 | 0.591715976331361 | 0.5882352941176471
Fer4 | 4Fe-4S binding domain | 92 | 380.587 | 2.326 | 1.891 | 3 | 79 | 1 | 1 | 6213 | 0 | 6308 | 0.04755865567533291 | 3.260869565217391 | 3.157894736842105
Lig_chan | Ligand-gated ion channel | 1090 | 734.934 | 2.338 | 2.301 | 1 | 433 | 1 | 1 | 67 | 0 | 1158 | 0.08635578583765112 | 0.09174311926605505 | 0.09165902841429881
CARD | Caspase recruitment domain | 508 | 599.045 | 2.447 | 1.811 | 17 | 113.824 | 1 | 1 | 0 | 0 | 525 | 3.238095238095238 | 3.346456692913386 | 3.238095238095238
SPRY | SPRY domain | 1504 | 652.878 | 2.529 | 2.241 | 3 | 376 | 1 | 1 | 172 | 0 | 1679 | 0.1786777843954735 | 0.199468085106383 | 0.19907100199071
[NAME] | [NAME] domain | 263 | 207.369 | 2.612 | 2.612 | 1 | 57 | 1 | 1 | 9262 | 0 | 9526 | 0.01049758555532227 | 0.3802281368821293 | 0.3787878787878788
SBP_bac_3 | Bacterial extracellular solute-binding proteins, family 3 | 473 | 756.541 | 2.632 | 2.592 | 1 | 316 | 1 | 1 | 9713 | 0 | 10187 | 0.009816432708353784 | 0.2114164904862579 | 0.2109704641350211
Y_phosphatase | Protein-tyrosine phosphatase | 1506 | 737.911 | 2.643 | 1.666 | 130 | 298.3 | 1 | 1 | 227 | 1 | 1863 | 6.977992485238863 | 8.632138114209829 | 7.946210268948656
[NAME] | Kunitz/Bovine pancreatic trypsin inhibitor domain | 1246 | 366.88 | 2.763 | 1.533 | 1 | 79 | 1 | 1 | 10 | 1 | 1257 | 0.07955449482895784 | 0.08025682182985554 | 0.08019246190858059
PDZ | PDZ domain (Also known as DHR or GLGF) | 3515 | 796.294 | 2.855 | 2.137 | 1 | 180 | 1 | 1 | 5662 | 0 | 9178 | 0.01089561996077577 | 0.02844950213371266 | 0.02844141069397042
[NAME]-beta | [NAME]-beta domain | 605 | 720.048 | 2.926 | 1.944 | 1 | 690 | 1 | 1 | 287 | 0 | 893 | 0.1119820828667413 | 0.1652892561983471 | 0.165016501650165
KH_1 | KH domain | 1147 | 554.42 | 3.177 | 1.454 | 1 | 111 | 1 | 1 | 2740 | 0 | 3888 | 0.0257201646090535 | 0.08718395815170009 | 0.08710801393728224
Flavodoxin_1 | Flavodoxin | 270 | 798.774 | 3.185 | 3.185 | 3 | 149.333 | 1 | 1 | 3089 | 0 | 3362 | 0.0892325996430696 | 1.111111111111111 | 1.098901098901099
Peptidase_M43 | Pregnancy-associated plasma protein-A | 15 | 1156.333 | 3.267 | 2.267 | 1 | 872 | 1 | 1 | 155 | 0 | 171 | 0.5847953216374269 | 6.666666666666667 | 6.25
Miro | Miro-like protein | 206 | 1017.354 | 3.364 | 2.67 | 2 | 237 | 1 | 1 | 154 | 1 | 362 | 0.5524861878453038 | 0.9708737864077669 | 0.9615384615384616
HECT | HECT-domain (ubiquitin-transferase) | 729 | 1152.837 | 3.421 | 1.995 | 1 | 964 | 1 | 1 | 325 | 0 | 1055 | 0.09478672985781991 | 0.1371742112482853 | 0.136986301369863
[NAME] | Zinc finger, C2H2 type | 9276 | 472.741 | 3.445 | 1.367 | 6 | 117.667 | 1 | 1 | 1020 | 0 | 10302 | 0.05824111822947001 | 0.0646830530401035 | 0.06464124111182934
Guanylate_kin | Guanylate kinase | 725 | 701.99 | 3.461 | 2.761 | 42 | 139.738 | 1 | 1 | 1728 | 2 | 2495 | 1.683366733466934 | 5.793103448275862 | 5.475880052151238
DMPK_coil | DMPK coiled coil domain like | 43 | 1156.605 | 3.86 | 3.837 | 1 | 98 | 1 | 1 | 0 | 0 | 44 | 2.272727272727273 | 2.325581395348837 | 2.272727272727273
Fer2 | 2Fe-2S iron-sulfur cluster binding domain | 287 | 792.244 | 3.899 | 3.882 | 1 | 97 | 1 | 1 | 7550 | 0 | 7838 | 0.01275835672365399 | 0.3484320557491289 | 0.3472222222222222
TIG | IPT/TIG domain | 490 | 1154.776 | 3.955 | 2.478 | 1 | 319 | 1 | 1 | 360 | 0 | 851 | 0.1175088131609871 | 0.2040816326530612 | 0.2036659877800407
GATase | Glutamine amidotransferase class-I | 1021 | 638.392 | 3.97 | 3.436 | 1 | 205 | 1 | 1 | 8800 | 0 | 9822 | 0.01018122581958868 | 0.0979431929480901 | 0.09784735812133072
PP-binding | Phosphopantetheine attachment site | 252 | 1303.306 | 4.063 | 3.75 | 1 | 87 | 1 | 1 | 10434 | 0 | 10687 | 0.009357162908206233 | 0.3968253968253968 | 0.3952569169960474
PA14 | PA14 domain | 40 | 1263.55 | 4.275 | 1.95 | 1 | 1174 | 1 | 1 | 583 | 0 | 624 | 0.1602564102564102 | 2.5 | 2.439024390243902
Formyl_trans_N | Formyl transferase | 150 | 793.8 | 4.353 | 4.127 | 2 | 189 | 1 | 1 | 4281 | 0 | 4433 | 0.04511617414843221 | 1.333333333333333 | 1.31578947368421
Herpes_UL45 | UL45 protein | 44 | 1338.159 | 4.682 | 2.045 | 81 | 178.321 | 1 | 1 | 0 | 2 | 125 | 64.8 | 184.0909090909091 | 64.8
CUB | CUB domain | 1507 | 781.461 | 4.975 | 2.297 | 2 | 270.5 | 1 | 1 | 6 | 1 | 1515 | 0.132013201320132 | 0.13271400132714 | 0.1325381047051027
TIL | Trypsin Inhibitor like cysteine rich domain | 551 | 896.485 | 5.528 | 2.087 | 8 | 221.375 | 1 | 1 | 2 | 1 | 561 | 1.42602495543672 | 1.451905626134301 | 1.431127012522361
CXCXC | CXCXC repeat | 30 | 456.8 | 5.6 | 1.7 | 3 | 99 | 1 | 1 | 2 | 1 | 35 | 8.571428571428571 | 10 | 9.090909090909092
EGF | EGF-like domain | 2127 | 1016.755 | 8.772 | 2.96 | 6 | 109.667 | 1 | 1 | 0 | 0 | 2133 | 0.2812939521800281 | 0.2820874471086037 | 0.2812939521800281
Laminin_G_2 | Laminin G domain | 1023 | 1605.735 | 9.467 | 2.965 | 5 | 1198.2 | 1 | 1 | 122 | 0 | 1150 | 0.4347826086956522 | 0.4887585532746823 | 0.4863813229571984
RyR | RyR domain | 63 | 4274.857 | 12.143 | 7.016 | 5 | 218.6 | 1 | 1 | 25 | 0 | 93 | 5.376344086021505 | 7.936507936507936 | 7.352941176470589
Herpes_gE | Alphaherpesvirus glycoprotein E | 5 | 227 | 1.4 | 1.4 | 184 | 433.886 | 1.011 | 1.011 | 2 | 0 | 191 | 96.33507853403141 | 3680 | 97.35449735449735
IL8 | Small cytokines (intecrine/chemokine), interleukin-8 like | 832 | 106.148 | 1 | 1 | 141 | 150.539 | 1.014 | 1.014 | 0 | 2 | 973 | 14.4912641315519 | 16.94711538461539 | 14.4912641315519
FGF | Fibroblast growth factor | 529 | 239.843 | 1.045 | 1.015 | 72 | 275.444 | 1.014 | 1 | 1 | 3 | 602 | 11.96013289036545 | 13.61058601134216 | 11.98003327787022
IstB | IstB-like ATP binding protein | 3 | 247.333 | 1 | 1 | 57 | 263.825 | 1.018 | 1.018 | 2368 | 0 | 2428 | 2.347611202635914 | 1900 | 95
Serpin | Serpin (serine protease inhibitor) | 1796 | 365.331 | 1.056 | 1.004 | 170 | 338.2 | 1.018 | 1 | 131 | 5 | 2097 | 8.106819265617549 | 9.465478841870825 | 8.646998982706002
CLP_protease | Clp protease | 45 | 241.2 | 1.044 | 1.022 | 52 | 263.058 | 1.019 | 1.019 | 2627 | 0 | 2724 | 1.908957415565345 | 115.5555555555555 | 53.60824742268041
YqaJ | YqaJ-like viral recombinase domain | 69 | 409.058 | 1.261 | 1.116 | 51 | 307.725 | 1.02 | 1.02 | 457 | 1 | 577 | 8.838821490467938 | 73.91304347826086 | 42.5
Glutaredoxin | Glutaredoxin | 305 | 263.803 | 1.518 | 1.436 | 101 | 97.475 | 1.02 | 1.02 | 3285 | 2 | 3691 | 2.736385803305337 | 33.11475409836066 | 24.8768472906404
Cauli_VI | Caulimovirus viroplasmin | 39 | 298.538 | 2.103 | 1.923 | 50 | 489.44 | 1.02 | 1.02 | 313 | 0 | 402 | 12.43781094527363 | 128.2051282051282 | 56.17977528089888
TK | Thymidine kinase | 33 | 199.879 | 1 | 1 | 123 | 178.35 | 1.024 | 1.016 | 829 | 7 | 985 | 12.48730964467005 | 372.7272727272727 | 78.84615384615384
Dam | DNA N-6-adenine-methyltransferase (Dam) | 4 | 885.25 | 2.25 | 2.25 | 37 | 181.216 | 1.027 | 1 | 118 | 0 | 159 | 23.27044025157233 | 925 | 90.2439024390244
zf-H2C2 | His(2)-Cys(2) zinc finger | 28 | 551.893 | 1.929 | 1.929 | 203 | 148.315 | 1.03 | 1.03 | 69 | 0 | 300 | 67.66666666666666 | 725 | 87.87878787878788
Band_7 | SPFH domain / Band 7 family | 542 | 340.428 | 1.063 | 1.041 | 31 | 299.355 | 1.032 | 1.032 | 4242 | 0 | 4815 | 0.6438213914849429 | 5.719557195571956 | 5.410122164048865
S1 | [NAME] binding domain | 247 | 722.279 | 2.567 | 2.291 | 30 | 102.933 | 1.033 | 1.033 | 8408 | 2 | 8685 | 0.3454231433506045 | 12.14574898785425 | 10.83032490974729
PP1c_bdg | Phosphatase-1 catalytic subunit binding region | 38 | 430.868 | 1.132 | 1.079 | 28 | 156.357 | 1.036 | 1 | 0 | 2 | 66 | 42.42424242424242 | 73.68421052631578 | 42.42424242424242
Thymidylate_kin | Thymidylate kinase | 61 | 225.754 | 1 | 1 | 51 | 223.353 | 1.039 | 1.039 | 1505 | 5 | 1617 | 3.153988868274583 | 83.60655737704919 | 45.53571428571428
UDG | Uracil DNA glycosylase superfamily | 101 | 483.792 | 1.03 | 1.01 | 141 | 265.957 | 1.043 | 1.043 | 3054 | 8 | 3296 | 4.277912621359223 | 139.6039603960396 | 58.26446280991735
V-set | [NAME]set domain | 5222 | 318.287 | 1.757 | 1.477 | 181 | 295.182 | 1.044 | 1.044 | 2 | 7 | 5405 | 3.348751156336725 | 3.466104940635772 | 3.349990745881917
DSPc | Dual specificity phosphatase, catalytic domain | 929 | 372.643 | 1.414 | 1.398 | 112 | 180.5 | 1.045 | 1.045 | 837 | 9 | 1878 | 5.963791267305645 | 12.05597416576964 | 10.75888568683958
Epimerase | NAD dependent epimerase/dehydratase family | 387 | 383.258 | 1.207 | 1.147 | 21 | 320.286 | 1.048 | 1.048 | 14411 | 0 | 14819 | 0.1417099669343411 | 5.426356589147287 | 5.147058823529411
Ribonuc_red_sm | Ribonucleotide reductase, small chain | 73 | 350.822 | 1 | 1 | 430 | 320.186 | 1.051 | 1.005 | 1479 | 9 | 1982 | 21.69525731584258 | 589.0410958904109 | 85.48707753479125
Thymidylat_synt | Thymidylate synthase | 72 | 268.083 | 1.042 | 1 | 92 | 286.337 | 1.054 | 1.022 | 1190 | 4 | 1354 | 6.794682422451995 | 127.7777777777778 | 56.09756097560976
TMV_coat | Virus coat protein (TMV like) | 12 | 287 | 1 | 1 | 422 | 279.137 | 1.059 | 1.059 | 0 | 0 | 434 | 97.23502304147466 | 3516.666666666667 | 97.23502304147466
[NAME] | Glycosyltransferase family 25 (LPS biosynthesis protein) | 46 | 514.261 | 1.065 | 1.043 | 16 | 273.875 | 1.062 | 1.062 | 613 | 1 | 675 | 2.37037037037037 | 34.78260869565217 | 25.80645161290322
XPG_I | XPG I-region | 162 | 638.37 | 1.901 | 1.901 | 272 | 337.199 | 1.066 | 1.066 | 352 | 3 | 786 | 34.60559796437659 | 167.9012345679012 | 62.67281105990783
FA_desaturase | Fatty acid desaturase | 553 | 338.709 | 1.277 | 1.277 | 14 | 200.929 | 1.071 | 1.071 | 2962 | 0 | 3529 | 0.3967129498441485 | 2.531645569620253 | 2.469135802469136
DHFR_1 | Dihydrofolate reductase | 66 | 173.788 | 1 | 1 | 40 | 210.75 | 1.075 | 1.05 | 1628 | 0 | 1734 | 2.306805074971165 | 60.60606060606061 | 37.73584905660378
bZIP_1 | bZIP transcription factor | 862 | 396.008 | 1.284 | 1.278 | 79 | 286.848 | 1.076 | 1.076 | 659 | 2 | 1600 | 4.9375 | 9.164733178654293 | 8.395324123273113
Aminotran_1_2 | [NAME] class I and II | 635 | 454.176 | 1.175 | 1.107 | 12 | 211.833 | 1.083 | 1 | 16764 | 0 | 17411 | 0.06892194589627247 | 1.889763779527559 | 1.854714064914992
HTH_11 | HTH domain | 30 | 337.067 | 1.933 | 1.933 | 11 | 356.909 | 1.091 | 1.091 | 4483 | 0 | 4524 | 0.2431476569407604 | 36.66666666666666 | 26.82926829268293
DUF1768 | Domain of unknown function (DUF1768) | 24 | 404.917 | 1.125 | 1 | 75 | 400.84 | 1.093 | 1.093 | 238 | 2 | 337 | 22.25519287833828 | 312.5 | 75.75757575757575
ig | Immunoglobulin domain | 1100 | 535.059 | 3.122 | 1.865 | 43 | 267.721 | 1.093 | 1.093 | 0 | 4 | 1143 | 3.762029746281715 | 3.909090909090909 | 3.762029746281715
Sema | Sema domain | 600 | 917.77 | 3.257 | 2.263 | 61 | 256.885 | 1.098 | 1.098 | 0 | 4 | 661 | 9.228441754916792 | 10.16666666666667 | 9.228441754916792
AIRS_C | AIR synthase related protein, C-terminal domain | 172 | 785.395 | 3.692 | 3.331 | 41 | 1215.829 | 1.098 | 1.049 | 4621 | 1 | 4834 | 0.848158874637981 | 23.83720930232558 | 19.24882629107981
PDGF | Platelet-derived growth factor (PDGF) | 242 | 213.045 | 1.393 | 1.318 | 20 | 149.5 | 1.1 | 1.1 | 0 | 0 | 262 | 7.633587786259542 | 8.264462809917356 | 7.633587786259542
NIF | NLI interacting factor-like phosphatase | 291 | 374.997 | 1.21 | 1.206 | 19 | 206.368 | 1.105 | 1.105 | 329 | 2 | 639 | 2.97339593114241 | 6.529209621993128 | 6.129032258064516
US22 | US22 like | 7 | 229.429 | 1 | 1 | 273 | 458.7 | 1.106 | 1.011 | 0 | 3 | 280 | 97.5 | 3900 | 97.5
Glyco_hydro_19 | Chitinase class I | 15 | 439.733 | 2 | 1.267 | 17 | 387.235 | 1.118 | 1.118 | 335 | 0 | 367 | 4.632152588555858 | 113.3333333333333 | 53.125
Rho_N | Rho termination factor, N-terminal domain | 4 | 911.75 | 2.5 | 2.5 | 25 | 297.04 | 1.12 | 1.12 | 1336 | 2 | 1365 | 1.831501831501832 | 625 | 86.20689655172413
Peptidase_M10 | [NAME] | 545 | 451.611 | 4.613 | 2.721 | 24 | 406 | 1.125 | 1.083 | 542 | 6 | 1111 | 2.16021602160216 | 4.403669724770642 | 4.21792618629174
Metallophos | Calcineurin-like phosphoesterase | 1515 | 395.67 | 1.299 | 1.275 | 76 | 332.789 | 1.132 | 1.132 | 11313 | 2 | 12904 | 0.5889646621202729 | 5.016501650165017 | 4.776869893148962
Chitin_bind_3 | Chitin binding domain | 64 | 269.984 | 1 | 1 | 58 | 300.966 | 1.138 | 1.138 | 589 | 1 | 711 | 8.157524613220815 | 90.625 | 47.54098360655738
IFNGR1 | Interferon gamma receptor (IFNGR1) | 28 | 337.286 | 1.714 | 1.714 | 58 | 267.362 | 1.138 | 1.138 | 0 | 2 | 86 | 67.44186046511628 | 207.1428571428572 | 67.44186046511628
[NAME] | Fic/DOC family | 31 | 451.581 | 1 | 1 | 7 | 282.286 | 1.143 | 1.143 | 1942 | 1 | 1980 | 0.3535353535353535 | 22.58064516129032 | 18.42105263157895
UPF0027 | Uncharacterized protein family UPF0027 | 55 | 427.2 | 1.055 | 1 | 7 | 436.571 | 1.143 | 1 | 613 | 0 | 675 | 1.037037037037037 | 12.72727272727273 | 11.29032258064516
[NAME] | [NAME] family | 4288 | 241.229 | 1.119 | 1.087 | 7 | 208.429 | 1.143 | 1.143 | 1607 | 0 | 5902 | 0.1186038630972552 | 0.1632462686567164 | 0.1629802095459837
Abhydrolase_1 | alpha/beta hydrolase fold | 1169 | 393.246 | 1.471 | 1.441 | 7 | 277.286 | 1.143 | 1.143 | 16365 | 0 | 17541 | 0.03990650476027592 | 0.5988023952095809 | 0.5952380952380952
TFIIB | Transcription factor [NAME] repeat | 96 | 431.812 | 3.104 | 2.281 | 7 | 334.143 | 1.143 | 1.143 | 137 | 0 | 240 | 2.916666666666667 | 7.291666666666667 | 6.796116504854369
Glycos_transf_2 | Glycosyl transferase family 2 | 640 | 518.502 | 1.681 | 1.677 | 68 | 405.618 | 1.147 | 1.147 | 16814 | 0 | 17522 | 0.3880835521059239 | 10.625 | 9.6045197740113
DNA_methylase | C-5 cytosine-specific DNA methylase | 144 | 778.021 | 2.486 | 2.208 | 81 | 358.704 | 1.148 | 1.025 | 1727 | 1 | 1952 | 4.149590163934426 | 56.25 | 36
Big_2 | Bacterial Ig-like domain (group 2) | 10 | 1516.8 | 1 | 1 | 56 | 291.786 | 1.161 | 1.125 | 1244 | 0 | 1310 | 4.274809160305344 | 560 | 84.84848484848484
TLV_coat | ENV polyprotein (coat polyprotein) | 260 | 474.388 | 1.135 | 1.042 | 1779 | 281.091 | 1.162 | 1.063 | 0 | 11 | 2039 | 87.2486512996567 | 684.2307692307692 | 87.2486512996567
UQ_con | Ubiquitin-conjugating enzyme | 1546 | 268.195 | 1.07 | 1.067 | 11 | 436.182 | 1.182 | 1.182 | 1044 | 0 | 2601 | 0.4229142637447136 | 0.7115135834411385 | 0.7064868336544637
fn3 | Fibronectin type III domain | 3521 | 1230.822 | 7.517 | 2.295 | 11 | 306.727 | 1.182 | 1.091 | 1381 | 0 | 4913 | 0.2238957866883778 | 0.312411246804885 | 0.3114382785956965
I-set | Immunoglobulin I-set domain | 6522 | 861.103 | 5.184 | 1.88 | 82 | 340.378 | 1.195 | 1.11 | 128 | 5 | 6732 | 1.218062982768865 | 1.257283042011653 | 1.241671714112659
TrmB | Sugar-specific transcriptional regulator TrmB | 11 | 329.636 | 1 | 1 | 5 | 114.8 | 1.2 | 1.2 | 660 | 0 | 676 | 0.7396449704142012 | 45.45454545454545 | 31.25
AP_endonuc_2 | [NAME] isomerase-like TIM barrel | 53 | 266.585 | 1 | 1 | 10 | 359.9 | 1.2 | 1.2 | 5001 | 1 | 5064 | 0.1974723538704581 | 18.86792452830189 | 15.87301587301587
TM2 | TM2 domain | 140 | 256.514 | 1.264 | 1.214 | 5 | 87.2 | 1.2 | 1.2 | 717 | 0 | 862 | 0.580046403712297 | 3.571428571428571 | 3.448275862068965
Pkinase | Protein kinase domain | 13536 | 550.132 | 1.893 | 1.385 | 376 | 371.779 | 1.202 | 1.069 | 12983 | 14 | 26895 | 1.398029373489496 | 2.777777777777778 | 2.702702702702703
Herpes_UL52 | [NAME] UL52/UL70 DNA primase | 13 | 585.769 | 1.385 | 1.385 | 111 | 932.171 | 1.207 | 1.198 | 0 | 2 | 124 | 89.51612903225806 | 853.8461538461538 | 89.51612903225806
zf-C3HC4 | Zinc finger, C3HC4 type (RING finger) | 4002 | 464.61 | 1.997 | 1.818 | 214 | 293.734 | 1.215 | 1.21 | 1335 | 8 | 5551 | 3.855161232210413 | 5.347326336831585 | 5.075901328273245
AAA_5 | AAA domain (dynein-related subfamily) | 390 | 3125.328 | 3.572 | 2.672 | 13 | 374.154 | 1.231 | 1.231 | 2099 | 0 | 2502 | 0.5195843325339728 | 3.333333333333333 | 3.225806451612903
RRM_1 | RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 6451 | 437.549 | 1.898 | 1.269 | 21 | 279.143 | 1.238 | 1.238 | 3925 | 0 | 10397 | 0.2019813407713763 | 0.3255309254379166 | 0.3244746600741656
HTH_3 | Helix-turn-helix | 70 | 150.3 | 1.929 | 1.929 | 460 | 133.104 | 1.239 | 1.237 | 20231 | 0 | 20761 | 2.215692885699148 | 657.1428571428571 | 86.79245283018868
AAA | ATPase family associated with various cellular activities (AAA) | 1971 | 567.387 | 1.838 | 1.702 | 70 | 380.457 | 1.243 | 1.171 | 15542 | 0 | 17583 | 0.3981118125462094 | 3.551496702181633 | 3.4296913277805
[NAME] | [NAME] | 37 | 209.568 | 1 | 1 | 4 | 233 | 1.25 | 1.25 | 2454 | 2 | 2495 | 0.1603206412825651 | 10.81081081081081 | 9.75609756097561
MT-A70 | MT-A70 | 91 | 438.56 | 1.011 | 1.011 | 4 | 260.25 | 1.25 | 1.25 | 178 | 0 | 273 | 1.465201465201465 | 4.395604395604396 | 4.210526315789473
ADP_ribosyl_GH | ADP-ribosylglycohydrolase | 82 | 366.72 | 1.207 | 1.073 | 4 | 360.25 | 1.25 | 1 | 730 | 0 | 816 | 0.4901960784313725 | 4.878048780487805 | 4.651162790697675
NAPRTase | Nicotinate phosphoribosyltransferase (NAPRTase) family | 78 | 466.154 | 1.256 | 1 | 16 | 508.562 | 1.25 | 1 | 1219 | 0 | 1313 | 1.218583396801219 | 20.51282051282051 | 17.02127659574468
Phosphodiest | Type I phosphodiesterase / nucleotide pyrophosphatase | 269 | 667.87 | 1.725 | 1.461 | 4 | 813 | 1.25 | 1.25 | 1118 | 2 | 1391 | 0.2875629043853343 | 1.486988847583643 | 1.465201465201465
APH | Phosphotransferase enzyme family | 71 | 527.014 | 2.085 | 2.07 | 12 | 368.833 | 1.25 | 1.25 | 6128 | 1 | 6211 | 0.1932056029624859 | 16.90140845070422 | 14.4578313253012
F5_F8_type_C | F5/8 type C domain | 1201 | 772.225 | 4.138 | 2.001 | 4 | 503.75 | 1.25 | 1 | 1407 | 0 | 2612 | 0.1531393568147014 | 0.3330557868442964 | 0.3319502074688797
SWIB | SWIB/MDM2 domain | 156 | 401.526 | 1.314 | 1.314 | 7 | 345.286 | 1.286 | 1.143 | 191 | 2 | 354 | 1.977401129943503 | 4.487179487179487 | 4.294478527607362
NUDIX | NUDIX domain | 607 | 292.107 | 1.242 | 1.213 | 162 | 251.16 | 1.309 | 1.309 | 13558 | 11 | 14327 | 1.130732183988274 | 26.68863261943987 | 21.06631989596879
[NAME] | [NAME] family | 29 | 224.897 | 1 | 1 | 3 | 318.333 | 1.333 | 1 | 36 | 0 | 68 | 4.411764705882353 | 10.3448275862069 | 9.375
DFP | DNA / pantothenate metabolism flavoprotein | 51 | 307.529 | 1.039 | 1.039 | 3 | 336.667 | 1.333 | 1.333 | 1420 | 2 | 1474 | 0.203527815468114 | 5.88235294117647 | 5.555555555555555
ATP_bind_3 | PP-loop family | 52 | 449.442 | 1.212 | 1.192 | 6 | 503.667 | 1.333 | 1.333 | 2342 | 0 | 2400 | 0.25 | 11.53846153846154 | 10.3448275862069
AAA_4 | Divergent AAA domain | 59 | 653.034 | 1.525 | 1.525 | 18 | 422.944 | 1.333 | 1.333 | 718 | 2 | 795 | 2.264150943396226 | 30.50847457627119 | 23.37662337662337
SWIM | SWIM zinc finger | 54 | 750.093 | 1.667 | 1.667 | 3 | 346.667 | 1.333 | 1 | 663 | 0 | 720 | 0.4166666666666667 | 5.555555555555555 | 5.263157894736842
VWA | [NAME] factor type A domain | 1650 | 739.973 | 3.365 | 1.972 | 6 | 630 | 1.333 | 1.333 | 2749 | 0 | 4405 | 0.1362088535754824 | 0.3636363636363636 | 0.3623188405797101
PAN_1 | PAN domain | 408 | 653.559 | 3.603 | 1.855 | 3 | 256.333 | 1.333 | 1 | 102 | 0 | 513 | 0.5847953216374269 | 0.7352941176470588 | 0.7299270072992701
SAP | SAP domain | 451 | 646.073 | 1.914 | 1.8 | 11 | 338.182 | 1.364 | 1.182 | 357 | 0 | 819 | 1.343101343101343 | 2.439024390243902 | 2.380952380952381
Lipase_GDSL | GDSL-like Lipase/Acylhydrolase | 142 | 422.338 | 1.176 | 1.077 | 8 | 508.25 | 1.375 | 1.375 | 3393 | 0 | 3543 | 0.2257973468811741 | 5.633802816901409 | 5.333333333333334
SLT | Transglycosylase SLT domain | 63 | 221.175 | 1.127 | 1.111 | 83 | 1175.506 | 1.386 | 1.386 | 4854 | 0 | 5000 | 1.66 | 131.7460317460317 | 56.84931506849315
DNA_primase_S | Eukaryotic and archaeal DNA primase small subunit | 50 | 406.42 | 1.1 | 1.1 | 74 | 396.757 | 1.392 | 1.392 | 365 | 7 | 489 | 15.13292433537832 | 148 | 59.67741935483871
Ribonuclease_3 | RNase3 domain | 177 | 1400.226 | 4.22 | 3.333 | 25 | 349.56 | 1.4 | 1.32 | 2017 | 2 | 2219 | 1.126633618747183 | 14.12429378531074 | 12.37623762376238
[NAME] | Interferon-regulatory factor 3 | 160 | 428.212 | 1.919 | 1.9 | 46 | 386.413 | 1.413 | 1.413 | 0 | 0 | 206 | 22.33009708737864 | 28.75 | 22.33009708737864
CTP_transf_2 | Cytidylyltransferase | 236 | 353.729 | 1.398 | 1.186 | 9 | 288.333 | 1.444 | 1.444 | 3888 | 0 | 4133 | 0.2177594967336076 | 3.813559322033898 | 3.673469387755103
Zeta_toxin | Zeta toxin | 77 | 706.857 | 2.286 | 2.273 | 22 | 407.273 | 1.455 | 1.455 | 660 | 0 | 759 | 2.898550724637681 | 28.57142857142857 | 22.22222222222222
CBM_14 | Chitin binding Peritrophin-A domain | 1810 | 524.23 | 2.806 | 1.274 | 118 | 422.576 | 1.466 | 1.458 | 22 | 2 | 1950 | 6.051282051282051 | 6.519337016574586 | 6.120331950207468
DUF862 | PPPDE putative peptidase domain | 72 | 209.847 | 1 | 1 | 12 | 1579.667 | 1.5 | 1.5 | 55 | 0 | 139 | 8.633093525179856 | 16.66666666666666 | 14.28571428571428
ART | NAD:arginine ADP-ribosyltransferase | 145 | 285.91 | 1.186 | 1.076 | 2 | 1313 | 1.5 | 1.5 | 58 | 0 | 205 | 0.975609756097561 | 1.379310344827586 | 1.360544217687075
Asn_synthase | Asparagine synthase | 89 | 519.697 | 1.247 | 1.247 | 2 | 528 | 1.5 | 1.5 | 1994 | 0 | 2085 | 0.09592326139088729 | 2.247191011235955 | 2.197802197802198
HMG_box | HMG (high mobility group) box | 2534 | 327.816 | 1.459 | 1.272 | 6 | 204.333 | 1.5 | 1 | 816 | 2 | 3356 | 0.1787842669845054 | 0.2367797947908445 | 0.2362204724409449
NTP_transferase | Nucleotidyl transferase | 157 | 399.076 | 1.49 | 1.42 | 6 | 381.333 | 1.5 | 1.5 | 8578 | 0 | 8741 | 0.0686420318041414 | 3.821656050955414 | 3.680981595092025
Peptidase_S8 | Subtilase family | 443 | 759.515 | 1.896 | 1.878 | 2 | 644 | 1.5 | 1.5 | 4263 | 0 | 4708 | 0.04248088360237893 | 0.4514672686230248 | 0.4494382022471911
RFC-E_C | Clamp-loader complex subunit E C-terminus | 44 | 338.045 | 1.909 | 1.909 | 2 | 347 | 1.5 | 1.5 | 59 | 0 | 105 | 1.904761904761905 | 4.545454545454546 | 4.347826086956522
AICARFT_IMPCHas | AICARFT/IMPCHase bienzyme | 50 | 566.58 | 1.94 | 1.92 | 2 | 254.5 | 1.5 | 1.5 | 1494 | 0 | 1546 | 0.129366106080207 | 4 | 3.846153846153846
DHH | DHH family | 28 | 457.393 | 1.964 | 1.964 | 2 | 576.5 | 1.5 | 1.5 | 3114 | 0 | 3144 | 0.06361323155216285 | 7.142857142857142 | 6.666666666666667
HTH_psq | helix-turn-helix, Psq domain | 189 | 713.46 | 2.169 | 1.598 | 2 | 475.5 | 1.5 | 1.5 | 519 | 0 | 710 | 0.2816901408450704 | 1.058201058201058 | 1.047120418848168
CBM_4_9 | Carbohydrate binding domain | 5 | 712 | 2.8 | 2 | 8 | 940.5 | 1.5 | 1.5 | 448 | 0 | 461 | 1.735357917570499 | 160 | 61.53846153846154
DHHA1 | DHHA1 domain | 51 | 862.608 | 2.863 | 2.824 | 2 | 494.5 | 1.5 | 1.5 | 3911 | 0 | 3964 | 0.05045408678102926 | 3.92156862745098 | 3.773584905660377
H2TH | Formamidopyrimidine-DNA glycosylase H2TH domain | 34 | 390.559 | 2.882 | 2.618 | 2 | 280.5 | 1.5 | 1.5 | 1537 | 0 | 1573 | 0.1271455816910362 | 5.88235294117647 | 5.555555555555555
Ku | Ku70/Ku80 beta-barrel domain | 120 | 604.333 | 3.058 | 3.058 | 2 | 283 | 1.5 | 1.5 | 554 | 0 | 676 | 0.2958579881656805 | 1.666666666666667 | 1.639344262295082
PKD | PKD domain | 109 | 1339.422 | 3.578 | 2.037 | 2 | 318 | 1.5 | 1 | 754 | 0 | 865 | 0.23121387283237 | 1.834862385321101 | 1.801801801801802
RCC1 | Regulator of chromosome condensation (RCC1) repeat | 557 | 1039.115 | 5.32 | 1.738 | 4 | 118.5 | 1.5 | 1 | 449 | 0 | 1010 | 0.3960396039603961 | 0.718132854578097 | 0.7130124777183601
FAD_binding_7 | FAD binding domain of DNA photolyase | 199 | 519.201 | 1.879 | 1.869 | 20 | 367.7 | 1.55 | 1.55 | 1371 | 3 | 1590 | 1.257861635220126 | 10.05025125628141 | 9.1324200913242
KaiC | KaiC | 17 | 491.882 | 1 | 1 | 7 | 399.714 | 1.571 | 1.571 | 1627 | 0 | 1651 | 0.4239854633555421 | 41.17647058823529 | 29.16666666666667
CBM_2 | Cellulose binding domain | 28 | 569.429 | 2.143 | 2 | 7 | 742.857 | 1.571 | 1.429 | 489 | 0 | 524 | 1.33587786259542 | 25 | 20
[NAME] | [NAME] domain | 155 | 480.845 | 1.284 | 1.155 | 79 | 490.962 | 1.595 | 1.038 | 0 | 4 | 234 | 33.76068376068376 | 50.96774193548386 | 33.76068376068376
NTP_transf_2 | Nucleotidyltransferase domain | 272 | 589.938 | 2.404 | 2.195 | 5 | 295.8 | 1.6 | 1.6 | 2834 | 0 | 3111 | 0.1607200257152041 | 1.838235294117647 | 1.805054151624549
zf-GRF | GRF zinc finger | 86 | 725.512 | 3.174 | 2.756 | 21 | 452.619 | 1.619 | 1.619 | 69 | 0 | 176 | 11.93181818181818 | 24.41860465116279 | 19.62616822429906
ResIII | Type III restriction enzyme, res subunit | 197 | 1030.34 | 2.071 | 2.03 | 228 | 586.838 | 1.627 | 1.623 | 5460 | 8 | 5885 | 3.874256584536959 | 115.736040609137 | 53.64705882352941
GP41 | Retroviral envelope protein | 36 | 626.083 | 1.167 | 1.167 | 17827 | 563.731 | 1.635 | 1.627 | 0 | 0 | 17863 | 99.79846610311817 | 49519.44444444445 | 99.79846610311817
BIR | Inhibitor of Apoptosis domain | 302 | 703.142 | 2.202 | 1.311 | 144 | 286.708 | 1.646 | 1.188 | 57 | 5 | 503 | 28.62823061630219 | 47.68211920529802 | 32.28699551569507
NMT | Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain | 68 | 459.25 | 1.956 | 1.956 | 3 | 318.667 | 1.667 | 1.667 | 63 | 1 | 134 | 2.238805970149254 | 4.411764705882353 | 4.225352112676056
tRNA_anti | OB-fold nucleic acid binding domain | 328 | 487.375 | 2.04 | 1.991 | 3 | 618.333 | 1.667 | 1.667 | 7717 | 0 | 8048 | 0.03727634194831014 | 0.9146341463414633 | 0.906344410876133
zf-FCS | MYM-type Zinc finger with FCS sequence motif | 105 | 1026.514 | 4.086 | 1.857 | 67 | 168.567 | 1.687 | 1.687 | 14 | 6 | 186 | 36.02150537634409 | 63.8095238095238 | 38.95348837209303
TNFR_c6 | TNFR/NGFR cysteine-rich region | 336 | 336.065 | 1.955 | 1.354 | 208 | 219.976 | 1.688 | 1.293 | 0 | 4 | 544 | 38.23529411764706 | 61.90476190476191 | 38.23529411764706
C1-set | [NAME]set domain | 8688 | 275.624 | 2.179 | 2.135 | 73 | 356.767 | 1.699 | 1.699 | 0 | 1 | 8761 | 0.8332382148156603 | 0.8402394106813995 | 0.8332382148156603
DED | Death effector domain | 249 | 564.217 | 2.446 | 1.767 | 21 | 191.286 | 1.714 | 1 | 0 | 1 | 270 | 7.777777777777778 | 8.433734939759036 | 7.777777777777778
Amidase_2 | N-acetylmuramoyl-L-alanine amidase | 349 | 260.937 | 1.089 | 1.011 | 145 | 306.455 | 1.717 | 1.538 | 2302 | 0 | 2796 | 5.185979971387697 | 41.54727793696275 | 29.35222672064777
DNA_ligase_A_M | ATP dependent DNA ligase domain | 115 | 801.913 | 3.383 | 3.278 | 153 | 440.889 | 1.719 | 1.706 | 1033 | 7 | 1301 | 11.76018447348194 | 133.0434782608696 | 57.08955223880597
DUF755 | Domain of unknown function (DUF755) | 10 | 1152.1 | 1 | 1 | 77 | 253.299 | 1.727 | 1.727 | 0 | 0 | 87 | 88.50574712643679 | 770 | 88.50574712643679
DNA_topoisoIV | DNA gyrase/topoisomerase IV, subunit A | 71 | 1216.014 | 2.845 | 2.803 | 37 | 812.973 | 1.73 | 1.676 | 4233 | 2 | 4341 | 0.8523381709283575 | 52.11267605633802 | 34.25925925925926
TFIIS_C | Transcription factor S-II (TFIIS) | 221 | 191.751 | 2.109 | 2.09 | 90 | 211.856 | 1.733 | 1.733 | 214 | 8 | 525 | 17.14285714285714 | 40.72398190045249 | 28.93890675241158
GMC_oxred_C | GMC oxidoreductase | 312 | 598.532 | 2.01 | 1.952 | 4 | 374.25 | 1.75 | 1.5 | 2811 | 0 | 3127 | 0.127918132395267 | 1.282051282051282 | 1.265822784810127
Avian_gp85 | Avian retrovirus envelope protein, gp85 | 7 | 440.714 | 2.143 | 2 | 117 | 487.65 | 1.752 | 1.752 | 0 | 3 | 124 | 94.35483870967742 | 1671.428571428572 | 94.35483870967742
Topoisom_I | Eukaryotic DNA topoisomerase I, catalytic core | 88 | 560.489 | 1.682 | 1.67 | 74 | 276.581 | 1.757 | 1.757 | 246 | 6 | 408 | 18.13725490196078 | 84.0909090909091 | 45.67901234567901
Cyclin_N | Cyclin, N-terminal domain | 1059 | 397.678 | 1.527 | 1.52 | 18 | 303.333 | 1.778 | 1.778 | 580 | 1 | 1657 | 1.086300543150271 | 1.69971671388102 | 1.671309192200557
BRCT | BRCA1 C Terminus (BRCT) domain | 537 | 882.495 | 2.875 | 2.218 | 14 | 371.5 | 1.786 | 1.714 | 2109 | 1 | 2660 | 0.5263157894736842 | 2.60707635009311 | 2.540834845735027
Peptidase_C1 | Papain family cysteine protease | 1620 | 309.455 | 1.687 | 1.677 | 60 | 348.617 | 1.8 | 1.783 | 180 | 4 | 1860 | 3.225806451612903 | 3.703703703703703 | 3.571428571428571
dsrm | Double-stranded RNA binding motif | 718 | 691.471 | 2.862 | 2.015 | 130 | 252.3 | 1.808 | 1.792 | 1559 | 4 | 2407 | 5.40091400083091 | 18.1058495821727 | 15.33018867924528
PCNA_N | Proliferating cell nuclear antigen, N-terminal domain | 114 | 214.632 | 1.833 | 1.833 | 27 | 265.148 | 1.815 | 1.815 | 58 | 0 | 199 | 13.5678391959799 | 23.68421052631579 | 19.14893617021277
WH2 | WH2 motif | 182 | 586.5 | 2.005 | 1.67 | 22 | 515.545 | 1.818 | 1 | 44 | 0 | 248 | 8.870967741935484 | 12.08791208791209 | 10.7843137254902
PLD_envelope | Phospholipase D/viral envelope | 73 | 465.959 | 1.795 | 1.767 | 168 | 291.893 | 1.821 | 1.446 | 20 | 5 | 261 | 64.36781609195403 | 230.1369863013699 | 69.70954356846472
Glyco_transf_10 | Glycosyltransferase family 10 (fucosyltransferase) | 392 | 377.671 | 1.059 | 1.015 | 6 | 814 | 1.833 | 1.833 | 79 | 0 | 477 | 1.257861635220126 | 1.530612244897959 | 1.507537688442211
DNA_photolyase | DNA photolyase | 181 | 548.011 | 1.972 | 1.961 | 13 | 450 | 1.846 | 1.846 | 1076 | 3 | 1270 | 1.023622047244094 | 7.18232044198895 | 6.701030927835052
DUF303 | Domain of unknown function (DUF303) | 18 | 481 | 1.167 | 1.111 | 20 | 583.75 | 1.85 | 1.85 | 505 | 0 | 543 | 3.683241252302026 | 111.1111111111111 | 52.63157894736842
Aminotran_3 | [NAME] class-III | 191 | 430.361 | 1.005 | 1 | 7 | 330.286 | 1.857 | 1 | 7671 | 0 | 7869 | 0.08895666539585716 | 3.664921465968586 | 3.535353535353535
TROVE | TROVE domain | 42 | 865.905 | 3.405 | 1.405 | 7 | 553 | 1.857 | 1 | 75 | 0 | 124 | 5.64516129032258 | 16.66666666666666 | 14.28571428571428
Glyco_hydro_18 | Glycosyl hydrolases family 18 | 808 | 527.442 | 1.559 | 1.335 | 66 | 605.894 | 1.879 | 1.864 | 3141 | 1 | 4015 | 1.643835616438356 | 8.16831683168317 | 7.551487414187644
Peptidase_S24 | Peptidase S24-like | 150 | 174.447 | 1 | 1 | 109 | 229.092 | 1.881 | 1.881 | 5449 | 0 | 5708 | 1.909600560616678 | 72.66666666666667 | 42.08494208494209
PG_binding_1 | Putative peptidoglycan binding domain | 404 | 497.483 | 5.265 | 3.072 | 33 | 325.818 | 1.909 | 1.879 | 2795 | 0 | 3232 | 1.021039603960396 | 8.16831683168317 | 7.551487414187644
PCNA_C | Proliferating cell nuclear antigen, C-terminal domain | 99 | 240.212 | 1.96 | 1.96 | 26 | 275 | 1.923 | 1.923 | 55 | 0 | 180 | 14.44444444444444 | 26.26262626262627 | 20.8
Peptidase_M23 | Peptidase family M23 | 22 | 699.591 | 1.136 | 1.091 | 50 | 1266.9 | 1.94 | 1.94 | 5933 | 0 | 6005 | 0.832639467110741 | 227.2727272727273 | 69.44444444444444
Herpes_gp2 | [NAME] herpesvirus glycoprotein gp2 | 7 | 467.143 | 1.571 | 1.429 | 36 | 481.694 | 1.944 | 1 | 1 | 0 | 44 | 81.81818181818183 | 514.2857142857143 | 83.72093023255815
IRF | Interferon regulatory factor transcription factor | 286 | 345.983 | 1.51 | 1.5 | 20 | 378.05 | 1.95 | 1.95 | 0 | 0 | 306 | 6.535947712418301 | 6.993006993006993 | 6.535947712418301
z-alpha | Adenosine deaminase z-alpha domain | 42 | 685.429 | 3.524 | 2.095 | 87 | 184.759 | 1.954 | 1.954 | 0 | 3 | 129 | 67.44186046511628 | 207.1428571428572 | 67.44186046511628
MHC_I | Class I Histocompatibility antigen, domains alpha 1 and 2 | 10553 | 222.392 | 1.666 | 1.666 | 51 | 354.941 | 1.98 | 1.98 | 0 | 0 | 10604 | 0.4809505846850245 | 0.4832748981332322 | 0.4809505846850245
ChitinaseA_N | Chitinase A, N-terminal domain | 9 | 554.778 | 2 | 2 | 54 | 556.241 | 1.981 | 1.981 | 130 | 1 | 193 | 27.97927461139896 | 600 | 85.71428571428571
Pox_MCEL | mRNA capping enzyme | 50 | 357.64 | 1 | 1 | 65 | 827.123 | 1.985 | 1.985 | 65 | 6 | 180 | 36.11111111111111 | 130 | 56.52173913043478
GIY-YIG | GIY-YIG catalytic domain | 39 | 295.564 | 1.385 | 1.359 | 125 | 204.808 | 1.992 | 1.384 | 3057 | 2 | 3221 | 3.88078236572493 | 320.5128205128206 | 76.21951219512195
MAP1_LC3 | Microtubule associated protein 1A/1B, light chain 3 | 207 | 120.923 | 1.005 | 1 | 2 | 289 | 2 | 2 | 63 | 0 | 272 | 0.7352941176470588 | 0.966183574879227 | 0.9569377990430622
Rad9 | Rad9 | 56 | 366.196 | 1.018 | 1.018 | 2 | 267.5 | 2 | 2 | 56 | 0 | 114 | 1.754385964912281 | 3.571428571428571 | 3.448275862068965
HCR | Alpha helical coiled-coil rod protein (HCR) | 92 | 311.935 | 1.043 | 1 | 1 | 235 | 2 | 2 | 0 | 0 | 93 | 1.075268817204301 | 1.08695652173913 | 1.075268817204301
RNB | RNB domain | 94 | 1136.394 | 1.074 | 1.032 | 1 | 528 | 2 | 2 | 1923 | 0 | 2018 | 0.04955401387512388 | 1.063829787234043 | 1.052631578947368
Sugar_tr | Sugar (and other) transporter | 1895 | 487.382 | 1.093 | 1.042 | 1 | 429 | 2 | 1 | 7481 | 0 | 9377 | 0.01066439159645942 | 0.05277044854881266 | 0.05274261603375527
Orn_Arg_deC_N | Pyridoxal-dependent decarboxylase, pyridoxal binding domain | 1052 | 104.147 | 1.121 | 1.12 | 6 | 371.833 | 2 | 2 | 2560 | 0 | 3618 | 0.1658374792703151 | 0.5703422053231939 | 0.5671077504725899
dTDP_sugar_isom | dTDP-4-dehydrorhamnose 3,5-epimerase | 6 | 239.333 | 1.167 | 1.167 | 1 | 393 | 2 | 2 | 1290 | 0 | 1297 | 0.07710100231303006 | 16.66666666666666 | 14.28571428571428
KTI12 | Chromatin associated protein KTI12 | 90 | 525.844 | 1.167 | 1.1 | 2 | 529.5 | 2 | 2 | 225 | 0 | 317 | 0.6309148264984227 | 2.222222222222222 | 2.173913043478261
B_lectin | D-mannose binding lectin | 11 | 113.545 | 1.182 | 1 | 1 | 199 | 2 | 1 | 53 | 0 | 65 | 1.538461538461539 | 9.090909090909092 | 8.333333333333332
AMP-binding | AMP-binding enzyme | 1475 | 599.211 | 1.289 | 1.184 | 1 | 832 | 2 | 2 | 19841 | 0 | 21317 | 0.00469109161701928 | 0.06779661016949153 | 0.06775067750677506
bZIP_Maf | bZIP Maf transcription factor | 161 | 246.05 | 1.329 | 1.329 | 1 | 369 | 2 | 2 | 2 | 1 | 164 | 0.6097560975609756 | 0.6211180124223602 | 0.6172839506172839
[NAME] | Domain found in IF2B/IF5 | 117 | 336.889 | 1.368 | 1.368 | 2 | 426 | 2 | 2 | 123 | 0 | 242 | 0.8264462809917356 | 1.70940170940171 | 1.680672268907563
DAO | FAD dependent oxidoreductase | 440 | 519.461 | 1.418 | 1.407 | 1 | 354 | 2 | 2 | 9991 | 0 | 10432 | 0.009585889570552147 | 0.2272727272727273 | 0.2267573696145125
Ski_Sno | SKI/SNO/DAC family | 196 | 586.204 | 1.5 | 1.495 | 1 | 437 | 2 | 2 | 0 | 1 | 197 | 0.5076142131979695 | 0.5102040816326531 | 0.5076142131979695
MR_MLE | Mandelate racemase / muconate lactonizing enzyme, C-terminal domain | 19 | 395.526 | 1.684 | 1.684 | 1 | 380 | 2 | 2 | 3161 | 0 | 3181 | 0.03143665513989311 | 5.263157894736842 | 5
G6PD_N | Glucose-6-phosphate dehydrogenase, NAD binding domain | 241 | 359.402 | 1.697 | 1.685 | 1 | 481 | 2 | 2 | 1401 | 0 | 1643 | 0.06086427267194157 | 0.4149377593360996 | 0.4132231404958678
EamA | EamA-like transporter family | 265 | 323.653 | 1.717 | 1.174 | 1 | 295 | 2 | 1 | 13142 | 0 | 13408 | 0.007458233890214798 | 0.3773584905660378 | 0.3759398496240601
LysR_substrate | LysR substrate binding domain | 11 | 230.545 | 1.727 | 1.727 | 1 | 297 | 2 | 2 | 32123 | 0 | 32135 | 0.003111871790882216 | 9.090909090909092 | 8.333333333333332
Jun | Jun-like transcription factor | 140 | 264.607 | 1.743 | 1.721 | 1 | 287 | 2 | 2 | 0 | 1 | 141 | 0.7092198581560284 | 0.7142857142857143 | 0.7092198581560284
Skp1_POZ | Skp1 family, tetramerisation domain | 243 | 156.374 | 1.757 | 1.753 | 6 | 152.5 | 2 | 2 | 102 | 0 | 351 | 1.70940170940171 | 2.469135802469136 | 2.409638554216868
Peptidase_M13_N | Peptidase family [NAME] | 703 | 621.492 | 1.782 | 1.713 | 1 | 615 | 2 | 2 | 608 | 0 | 1312 | 0.07621951219512195 | 0.1422475106685633 | 0.1420454545454546
XPG_N | XPG N-terminal domain | 174 | 628.833 | 1.833 | 1.833 | 18 | 358.222 | 2 | 2 | 297 | 3 | 489 | 3.680981595092025 | 10.3448275862069 | 9.375
Peptidase_M13 | Peptidase family [NAME] | 645 | 625.786 | 1.85 | 1.778 | 1 | 615 | 2 | 2 | 578 | 0 | 1224 | 0.08169934640522876 | 0.1550387596899225 | 0.1547987616099071
[NAME] | eIF4-gamma/eIF5/eIF2-epsilon | 243 | 686.593 | 1.864 | 1.864 | 2 | 426 | 2 | 2 | 115 | 0 | 360 | 0.5555555555555556 | 0.823045267489712 | 0.8163265306122449
G6PD_C | Glucose-6-phosphate dehydrogenase, C-terminal domain | 194 | 406.031 | 1.871 | 1.851 | 1 | 481 | 2 | 2 | 1603 | 0 | 1798 | 0.05561735261401557 | 0.5154639175257731 | 0.5128205128205128
Sod_Fe_C | Iron/manganese superoxide dismutases, C-terminal domain | 186 | 201.769 | 1.876 | 1.876 | 1 | 204 | 2 | 2 | 3239 | 0 | 3426 | 0.02918855808523059 | 0.5376344086021506 | 0.53475935828877
Gln-synt_C | Glutamine synthetase, catalytic domain | 130 | 371.131 | 1.9 | 1.892 | 1 | 353 | 2 | 2 | 4018 | 0 | 4149 | 0.02410219329959026 | 0.7692307692307693 | 0.7633587786259541
Skp1 | Skp1 family, dimerisation domain | 205 | 169.522 | 1.902 | 1.898 | 6 | 152.5 | 2 | 2 | 63 | 0 | 274 | 2.18978102189781 | 2.926829268292683 | 2.843601895734597
PDGF_N | Platelet-derived growth factor, N terminal region | 54 | 200.611 | 1.907 | 1.907 | 2 | 248.5 | 2 | 2 | 0 | 0 | 56 | 3.571428571428571 | 3.703703703703703 | 3.571428571428571
Tissue_fac | Tissue factor | 251 | 386.944 | 1.908 | 1.825 | 8 | 269.625 | 2 | 2 | 1 | 0 | 260 | 3.076923076923077 | 3.187250996015936 | 3.088803088803089
Arrestin_N | Arrestin (or S-antigen), N-terminal domain | 597 | 399.926 | 1.915 | 1.888 | 1 | 306 | 2 | 2 | 286 | 1 | 884 | 0.1131221719457014 | 0.1675041876046901 | 0.1672240802675585
Sod_Fe_N | Iron/manganese superoxide dismutases, alpha-hairpin domain | 177 | 209.136 | 1.921 | 1.921 | 1 | 204 | 2 | 2 | 3102 | 0 | 3280 | 0.03048780487804878 | 0.5649717514124294 | 0.5617977528089888
2-Hacid_dh_C | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain | 246 | 375.984 | 1.923 | 1.919 | 3 | 351.667 | 2 | 2 | 6195 | 0 | 6444 | 0.04655493482309125 | 1.219512195121951 | 1.204819277108434
MR_MLE_N | Mandelate racemase / muconate lactonizing enzyme, N-terminal domain | 14 | 409.071 | 1.929 | 1.929 | 1 | 380 | 2 | 2 | 2532 | 0 | 2547 | 0.03926187671770711 | 7.142857142857142 | 6.666666666666667
NMT_C | Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain | 70 | 450.886 | 1.929 | 1.929 | 2 | 328.5 | 2 | 2 | 73 | 0 | 145 | 1.379310344827586 | 2.857142857142857 | 2.777777777777778
Gln-synt_N | Glutamine synthetase, beta-Grasp domain | 124 | 372.056 | 1.944 | 1.935 | 1 | 353 | 2 | 2 | 2286 | 0 | 2411 | 0.04147656574035669 | 0.8064516129032258 | 0.8
Orn_DAP_Arg_deC | Pyridoxal-dependent decarboxylase, C-terminal sheet domain | 133 | 409.045 | 1.947 | 1.94 | 6 | 371.833 | 2 | 2 | 2703 | 0 | 2842 | 0.211118930330753 | 4.511278195488721 | 4.316546762589928
Lipid_DES | Sphingolipid Delta4-desaturase (DES) | 66 | 310.848 | 1.955 | 1.955 | 1 | 320 | 2 | 2 | 55 | 0 | 122 | 0.819672131147541 | 1.515151515151515 | 1.492537313432836
ADH_N | Alcohol dehydrogenase GroES-like domain | 539 | 400.963 | 1.957 | 1.944 | 1 | 422 | 2 | 2 | 13157 | 0 | 13697 | 0.007300868803387604 | 0.1855287569573284 | 0.1851851851851852
Arrestin_C | Arrestin (or S-antigen), C-terminal domain | 561 | 410.672 | 1.97 | 1.943 | 1 | 306 | 2 | 2 | 255 | 1 | 817 | 0.1223990208078335 | 0.17825311942959 | 0.1779359430604982
Rep_fac_C | Replication factor C | 124 | 335.718 | 1.976 | 1.968 | 5 | 331.2 | 2 | 2 | 178 | 0 | 307 | 1.628664495114007 | 4.032258064516129 | 3.875968992248062
c-SKI_SMAD_bind | c-SKI Smad4 binding domain | 98 | 539.837 | 1.99 | 1.98 | 1 | 437 | 2 | 2 | 0 | 1 | 99 | 1.01010101010101 | 1.020408163265306 | 1.01010101010101
Inhibitor_I29 | Cathepsin propeptide inhibitor domain (I29) | 873 | 337.554 | 1.991 | 1.946 | 47 | 335.383 | 2 | 2 | 0 | 2 | 920 | 5.108695652173913 | 5.383734249713632 | 5.108695652173913
DUF583 | Protein of unknown function, DUF583 | 3 | 131.667 | 2 | 1 | 1 | 982 | 2 | 1 | 818 | 0 | 822 | 0.121654501216545 | 33.33333333333333 | 25
HTH_1 | Bacterial regulatory helix-turn-helix protein, [NAME] family | 8 | 247.5 | 2 | 2 | 1 | 297 | 2 | 2 | 32410 | 0 | 32419 | 0.00308461087633795 | 12.5 | 11.11111111111111
Maf_N | Maf N-terminal region | 53 | 316.302 | 2 | 2 | 1 | 369 | 2 | 2 | 0 | 1 | 54 | 1.851851851851852 | 1.886792452830189 | 1.851851851851852
GMC_oxred_N | GMC oxidoreductase | 311 | 602.646 | 2.01 | 1.955 | 4 | 529.25 | 2 | 1.5 | 2648 | 0 | 2963 | 0.1349983125210935 | 1.286173633440514 | 1.26984126984127
2-Hacid_dh | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain | 224 | 391.411 | 2.013 | 2.009 | 3 | 351.667 | 2 | 2 | 5177 | 0 | 5404 | 0.05551443375277572 | 1.339285714285714 | 1.3215859030837
DALR_1 | [NAME] binding domain | 107 | 522.953 | 2.019 | 1.991 | 1 | 600 | 2 | 2 | 2329 | 0 | 2437 | 0.04103405826836274 | 0.9345794392523363 | 0.9259259259259258
CD47 | CD47 transmembrane region | 15 | 304.867 | 2.067 | 2 | 42 | 281.286 | 2 | 2 | 0 | 3 | 57 | 73.68421052631578 | 280 | 73.68421052631578
R3H | R3H domain | 193 | 783.907 | 2.166 | 1.979 | 1 | 399 | 2 | 2 | 695 | 0 | 889 | 0.1124859392575928 | 0.5181347150259068 | 0.5154639175257731
LNS2 | LNS2 (Lipin/Ned1/Smp2) | 122 | 892.303 | 2.189 | 2.09 | 1 | 292 | 2 | 2 | 71 | 0 | 194 | 0.5154639175257731 | 0.819672131147541 | 0.8130081300813009
ADH_zinc_N | Zinc-binding dehydrogenase | 732 | 539.016 | 2.251 | 2.238 | 1 | 422 | 2 | 2 | 13730 | 0 | 14463 | 0.006914194842010648 | 0.1366120218579235 | 0.1364256480218281
[NAME] | Peptidase M16 inactive domain | 373 | 651.893 | 2.271 | 1.954 | 1 | 440 | 2 | 2 | 3699 | 0 | 4073 | 0.02455192732629511 | 0.2680965147453083 | 0.267379679144385
GTP_EFTU | Elongation factor [NAME] binding domain | 10098 | 319.597 | 2.274 | 2.272 | 1 | 480 | 2 | 2 | 16623 | 0 | 26722 | 0.00374223486265998 | 0.009902951079421667 | 0.009901970492127933
V-set_CD47 | CD47 immunoglobulin-like domain | 17 | 427.647 | 2.294 | 2.118 | 42 | 281.286 | 2 | 2 | 0 | 3 | 59 | 71.1864406779661 | 247.0588235294118 | 71.1864406779661
Peptidase_M16 | Insulinase ([NAME] family M16) | 345 | 651.052 | 2.31 | 2 | 1 | 440 | 2 | 2 | 3291 | 0 | 3637 | 0.02749518834204015 | 0.2898550724637681 | 0.2890173410404624
Peptidase_M41 | Peptidase family M41 | 131 | 659.374 | 2.328 | 2.305 | 1 | 579 | 2 | 2 | 2147 | 0 | 2279 | 0.04387889425186486 | 0.7633587786259541 | 0.7575757575757576
ABC_tran | ABC transporter | 2459 | 907.201 | 2.386 | 1.685 | 9 | 930.222 | 2 | 1.222 | 94830 | 1 | 97298 | 0.009249933194926925 | 0.3660024400162668 | 0.3646677471636953
FYVE | FYVE zinc finger | 656 | 862.468 | 2.529 | 2.012 | 1 | 701 | 2 | 2 | 280 | 0 | 937 | 0.1067235859124867 | 0.1524390243902439 | 0.15220700152207
Lon_C | Lon protease (S16) C-terminal proteolytic domain | 78 | 743.744 | 2.577 | 2.551 | 1 | 1023 | 2 | 2 | 3709 | 0 | 3788 | 0.02639915522703273 | 1.282051282051282 | 1.265822784810127
RFC1 | Replication factor RFC1 C terminal domain | 38 | 851.789 | 2.579 | 2.579 | 1 | 533 | 2 | 2 | 65 | 0 | 104 | 0.9615384615384616 | 2.631578947368421 | 2.564102564102564
Nucleos_tra2_C | Na+ dependent nucleoside transporter C-terminus | 81 | 571.395 | 2.593 | 2.543 | 1 | 579 | 2 | 2 | 1434 | 0 | 1516 | 0.06596306068601583 | 1.234567901234568 | 1.219512195121951
GTP_EFTU_D3 | Elongation factor [NAME] domain | 6478 | 320.357 | 2.616 | 2.615 | 1 | 480 | 2 | 2 | 4016 | 0 | 10495 | 0.009528346831824679 | 0.01543686322939179 | 0.01543448062972681
Nucleos_tra2_N | Na+ dependent nucleoside transporter N-terminus | 75 | 592.453 | 2.693 | 2.667 | 1 | 579 | 2 | 2 | 1417 | 0 | 1493 | 0.06697923643670461 | 1.333333333333333 | 1.31578947368421
TFIIS_M | Transcription factor S-II (TFIIS), central domain | 140 | 615.686 | 2.8 | 2.764 | 9 | 183.556 | 2 | 2 | 110 | 0 | 259 | 3.474903474903475 | 6.428571428571428 | 6.04026845637584
Fapy_DNA_glyco | Formamidopyrimidine-DNA glycosylase N-terminal domain | 26 | 371.154 | 2.885 | 2.731 | 1 | 287 | 2 | 2 | 1510 | 0 | 1537 | 0.06506180871828238 | 3.846153846153846 | 3.703703703703703
C2-set_2 | CD80-like C2-set immunoglobulin domain | 1031 | 584.974 | 2.896 | 2.237 | 1 | 284 | 2 | 2 | 0 | 0 | 1032 | 0.09689922480620156 | 0.09699321047526674 | 0.09689922480620156
TF_Zn_Ribbon | TFIIB zinc-binding | 113 | 432.584 | 2.956 | 2.301 | 1 | 461 | 2 | 2 | 130 | 0 | 244 | 0.4098360655737705 | 0.8849557522123894 | 0.8771929824561403
PAS_4 | PAS fold | 9 | 1015 | 3 | 3 | 1 | 235 | 2 | 2 | 7249 | 0 | 7259 | 0.01377600220416035 | 11.11111111111111 | 10
PSI | Plexin repeat | 547 | 1091.786 | 3.943 | 2.634 | 6 | 562.667 | 2 | 2 | 7 | 2 | 560 | 1.071428571428571 | 1.096892138939671 | 1.08499095840868
OTCace_N | Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain | 74 | 1076.77 | 5.311 | 4.568 | 3 | 321.667 | 2 | 2 | 3191 | 0 | 3268 | 0.09179926560587516 | 4.054054054054054 | 3.896103896103896
PT | PT repeat | 36 | 665.25 | 5.528 | 3.083 | 1 | 81 | 2 | 1 | 73 | 0 | 110 | 0.9090909090909091 | 2.777777777777778 | 2.702702702702703
MGS | MGS-like domain | 104 | 1208.51 | 5.654 | 4.731 | 1 | 196 | 2 | 2 | 3361 | 0 | 3466 | 0.02885170225043278 | 0.9615384615384616 | 0.9523809523809524
RHS_repeat | RHS Repeat | 17 | 2428.294 | 5.824 | 2.353 | 1 | 1683 | 2 | 1 | 1250 | 0 | 1268 | 0.07886435331230283 | 5.88235294117647 | 5.555555555555555
OTCace | Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain | 63 | 1195.937 | 6.032 | 5.175 | 3 | 321.667 | 2 | 2 | 3186 | 0 | 3252 | 0.09225092250922509 | 4.761904761904762 | 4.545454545454546
zf-CCCH | Zinc finger C-x8-C-x5-C-x3-H type (and similar) | 816 | 465.881 | 1.854 | 1.433 | 32 | 189.906 | 2.031 | 2.031 | 394 | 1 | 1242 | 2.576489533011272 | 3.92156862745098 | 3.773584905660377
SNF2_N | SNF2 family N-terminal domain | 836 | 1266.578 | 3.132 | 2.85 | 156 | 647.635 | 2.122 | 2.122 | 3408 | 8 | 4400 | 3.545454545454545 | 18.66028708133971 | 15.7258064516129
Ribonuc_red_lgC | Ribonucleotide reductase, barrel domain | 53 | 726.358 | 2.717 | 2.717 | 270 | 709.507 | 2.133 | 2.07 | 1978 | 9 | 2301 | 11.73402868318123 | 509.433962264151 | 83.59133126934985
Pkinase_Tyr | Protein tyrosine kinase | 4626 | 728.206 | 2.46 | 2.072 | 67 | 557.388 | 2.134 | 2.09 | 175 | 17 | 4868 | 1.376335250616269 | 1.448335495028102 | 1.427658214361816
DNA_gyraseB | DNA gyrase B | 63 | 1279.127 | 3.111 | 3.095 | 37 | 881.919 | 2.135 | 2.108 | 7981 | 2 | 8081 | 0.457864125727014 | 58.73015873015873 | 37
LRR_1 | Leucine Rich Repeat | 7114 | 534.426 | 3.659 | 1.656 | 7 | 513.571 | 2.143 | 1 | 2019 | 0 | 9140 | 0.07658643326039387 | 0.09839752600506045 | 0.09830080044937509
mRNA_cap_enzyme | mRNA capping enzyme, catalytic domain | 51 | 558.667 | 2.765 | 2.745 | 18 | 609 | 2.167 | 2.167 | 66 | 0 | 135 | 13.33333333333333 | 35.29411764705883 | 26.08695652173913
mRNA_cap_C | mRNA capping enzyme, C-terminal domain | 42 | 592.024 | 2.952 | 2.929 | 9 | 366.778 | 2.222 | 2.222 | 61 | 0 | 112 | 8.035714285714286 | 21.42857142857143 | 17.64705882352941
zf-C4 | Zinc finger, C4 type (two domains) | 3447 | 444.594 | 1.936 | 1.915 | 4 | 663.5 | 2.25 | 2.25 | 0 | 1 | 3451 | 0.1159084323384526 | 0.1160429358862779 | 0.1159084323384526
Hormone_recep | Ligand-binding domain of nuclear hormone receptor | 3107 | 460.433 | 2.014 | 1.998 | 4 | 663.5 | 2.25 | 2.25 | 0 | 1 | 3111 | 0.1285760205721633 | 0.1287415513356936 | 0.1285760205721633
HATPase_c | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | 763 | 625.823 | 2.109 | 2.081 | 45 | 707.2 | 2.267 | 2.244 | 50311 | 2 | 51119 | 0.08802989103855709 | 5.897771952817824 | 5.569306930693069
LysM | LysM domain | 154 | 516.175 | 1.623 | 1.474 | 48 | 453.917 | 2.312 | 1.771 | 5935 | 0 | 6137 | 0.7821411112921623 | 31.16883116883117 | 23.76237623762376
ubiquitin | [NAME] family | 1617 | 326.73 | 2.084 | 1.562 | 89 | 399.596 | 2.315 | 2.067 | 593 | 3 | 2299 | 3.871248368856024 | 5.504019789734076 | 5.216881594372802
[NAME] | Retroviral aspartyl protease | 172 | 601.831 | 2.453 | 2.366 | 75597 | 319.886 | 2.35 | 2.343 | 271 | 5 | 76040 | 99.41741188847975 | 43951.74418604651 | 99.77299423246974
GATase_2 | Glutamine amidotransferases class-II | 179 | 764.95 | 2.838 | 2.363 | 11 | 516.364 | 2.364 | 1.727 | 4934 | 0 | 5124 | 0.2146760343481655 | 6.145251396648044 | 5.789473684210527
Hydrolase | haloacid dehalogenase-like hydrolase | 1301 | 784.905 | 2.646 | 2.482 | 5 | 574.2 | 2.4 | 2.4 | 19282 | 0 | 20588 | 0.02428599183990674 | 0.3843197540353574 | 0.3828483920367535
Myc_N | Myc amino-terminal region | 1332 | 194.935 | 2.201 | 2.185 | 24 | 289.417 | 2.417 | 2.333 | 0 | 6 | 1356 | 1.769911504424779 | 1.801801801801802 | 1.769911504424779
Ank | Ankyrin repeat | 4663 | 737.059 | 4.336 | 1.79 | 457 | 462.204 | 2.481 | 1.446 | 3871 | 7 | 8991 | 5.082860638416194 | 9.800557580956466 | 8.92578125
An_peroxidase | Animal haem peroxidase | 526 | 768.053 | 1.962 | 1.582 | 2 | 581 | 2.5 | 1 | 202 | 0 | 730 | 0.273972602739726 | 0.3802281368821293 | 0.3787878787878788
DnaJ_C | DnaJ C terminal region | 385 | 369.787 | 2.343 | 2.332 | 4 | 304 | 2.5 | 2.5 | 2930 | 0 | 3319 | 0.1205182283820428 | 1.038961038961039 | 1.02827763496144
[NAME] | [NAME] (NUC185) domain | 89 | 1003.989 | 2.73 | 2.708 | 6 | 718.167 | 2.5 | 2.5 | 271 | 0 | 366 | 1.639344262295082 | 6.741573033707865 | 6.315789473684211
WD40 | WD domain, G-beta repeat | 7746 | 631.842 | 4.473 | 1.391 | 4 | 411 | 2.5 | 1.5 | 7209 | 0 | 14959 | 0.02673975533123872 | 0.05163955589981926 | 0.05161290322580645
Hemopexin | Hemopexin | 554 | 451.108 | 4.758 | 2.605 | 2 | 646.5 | 2.5 | 2 | 18 | 0 | 574 | 0.3484320557491289 | 0.3610108303249098 | 0.3597122302158274
Gag_p24 | gag gene protein p24 (core nucleocapsid protein) | 73 | 548.123 | 3.082 | 2.658 | 21914 | 295.652 | 2.501 | 2.202 | 0 | 5 | 21987 | 99.66798562787102 | 30019.17808219178 | 99.66798562787102
Ribonuc_red_lgN | Ribonucleotide reductase, all-alpha domain | 47 | 772.298 | 2.936 | 2.936 | 197 | 771.061 | 2.513 | 2.472 | 1579 | 6 | 1823 | 10.80636313768514 | 419.1489361702128 | 80.73770491803278
DnaJ | DnaJ domain | 1709 | 400.564 | 1.801 | 1.682 | 443 | 493.995 | 2.519 | 2.519 | 6449 | 0 | 8601 | 5.15056388792001 | 25.92159157401989 | 20.58550185873606
[NAME] | Glycosyl hydrolases family 25 | 8 | 222.875 | 1 | 1 | 48 | 376.25 | 2.562 | 1.854 | 1098 | 0 | 1154 | 4.15944540727903 | 600 | 85.71428571428571
UPF0547 | Uncharacterised protein family UPF0547 | 11 | 161.909 | 1 | 1 | 7 | 355.143 | 2.571 | 2.429 | 84 | 0 | 102 | 6.862745098039216 | 63.63636363636363 | 38.88888888888889
dUTPase | dUTPase | 77 | 256.052 | 1.883 | 1.792 | 563 | 355.318 | 2.575 | 2.526 | 1891 | 15 | 2531 | 22.2441722639273 | 731.1688311688312 | 87.96875
Toprim | Toprim domain | 79 | 813.835 | 3.013 | 2.709 | 43 | 565.465 | 2.581 | 2.558 | 8022 | 0 | 8144 | 0.5279960707269155 | 54.43037974683544 | 35.24590163934426
Adeno_E3_CR2 | Adenovirus E3 region protein CR2 | 4 | 375.5 | 3 | 3 | 80 | 257.663 | 2.6 | 2 | 0 | 0 | 84 | 95.23809523809523 | 2000 | 95.23809523809523
T_Ag_DNA_bind | Origin of replication binding protein | 3 | 333.667 | 1.667 | 1.667 | 344 | 607.073 | 2.66 | 2.66 | 0 | 0 | 347 | 99.13544668587896 | 11466.66666666667 | 99.13544668587896
Ham1p_like | [NAME] family | 45 | 189.289 | 1 | 1 | 9 | 699.333 | 2.667 | 2.667 | 1471 | 0 | 1525 | 0.5901639344262295 | 20 | 16.66666666666666
PI3_PI4_kinase | Phosphatidylinositol 3- and 4-kinase | 537 | 1413.117 | 2.916 | 2.87 | 3 | 682.667 | 2.667 | 2.667 | 546 | 0 | 1086 | 0.2762430939226519 | 0.5586592178770949 | 0.5555555555555556
Cmyb_C | C-myb, C-terminal | 78 | 575.526 | 3.795 | 2.282 | 3 | 304 | 2.667 | 2.333 | 0 | 1 | 81 | 3.703703703703703 | 3.846153846153846 | 3.703703703703703
SIS | SIS domain | 80 | 611.812 | 2.987 | 1.837 | 8 | 554.25 | 2.75 | 1.875 | 7731 | 0 | 7819 | 0.1023148740248114 | 10 | 9.090909090909092
SH3_1 | SH3 domain | 3103 | 681.96 | 3.419 | 2.398 | 28 | 468.179 | 2.75 | 2.75 | 1078 | 6 | 4209 | 0.6652411499168448 | 0.9023525620367387 | 0.8942829766847652
Wos2 | Wos2 motif | 46 | 554.978 | 4.239 | 2.652 | 4 | 395.25 | 2.75 | 2.5 | 0 | 2 | 50 | 8 | 8.695652173913043 | 8
SH2 | SH2 domain | 2299 | 576.555 | 2.79 | 2.568 | 39 | 524.205 | 2.769 | 2.769 | 39 | 7 | 2377 | 1.640723601177956 | 1.696389734667247 | 1.668092386655261
UDPG_MGDP_dh | UDP-glucose/GDP-mannose dehydrogenase family, central domain | 49 | 456.776 | 2.918 | 2.918 | 9 | 375.778 | 2.778 | 2.778 | 2366 | 0 | 2424 | 0.3712871287128713 | 18.36734693877551 | 15.51724137931035
FCH | Fes/CIP4 homology domain | 408 | 636.436 | 2.066 | 2.005 | 5 | 656.4 | 2.8 | 2.8 | 265 | 1 | 678 | 0.7374631268436578 | 1.225490196078431 | 1.210653753026634
G-patch | G-patch domain | 699 | 592.628 | 1.851 | 1.82 | 38 | 319.842 | 2.816 | 2.789 | 344 | 1 | 1081 | 3.515263644773358 | 5.436337625178827 | 5.156037991858888
Phlebovirus_G2 | Phlebovirus glycoprotein G2 | 6 | 1396 | 3.667 | 3.5 | 120 | 875.158 | 2.833 | 2.425 | 0 | 3 | 126 | 95.23809523809523 | 2000 | 95.23809523809523
PLDc | Phospholipase D Active site motif | 113 | 767.549 | 2.345 | 2.035 | 75 | 374.987 | 2.84 | 2 | 1890 | 5 | 2078 | 3.609239653512993 | 66.3716814159292 | 39.8936170212766
ATP-cone | ATP cone domain | 44 | 774.545 | 2.977 | 2.977 | 96 | 745.99 | 2.885 | 2.875 | 2510 | 3 | 2650 | 3.622641509433962 | 218.1818181818182 | 68.57142857142857
Pentapeptide | Pentapeptide repeats (8 copies) | 42 | 289.024 | 4.333 | 1.929 | 10 | 231.2 | 2.9 | 1 | 2421 | 0 | 2473 | 0.4043671653861707 | 23.80952380952381 | 19.23076923076923
DNA_ligase_A_N | DNA ligase N terminus | 122 | 783.475 | 3.238 | 3.148 | 55 | 562.836 | 2.909 | 2.909 | 402 | 4 | 579 | 9.499136442141623 | 45.08196721311475 | 31.07344632768362
HLH | Helix-loop-helix DNA-binding domain | 4106 | 322.781 | 1.802 | 1.787 | 17 | 404.647 | 2.941 | 2.882 | 513 | 6 | 4636 | 0.3666954270923209 | 0.4140282513395032 | 0.4123211253941305
DNA_ligase_A_C | ATP dependent DNA ligase C terminal region | 105 | 816.695 | 3.524 | 3.41 | 54 | 566.759 | 2.963 | 2.944 | 745 | 5 | 904 | 5.973451327433628 | 51.42857142857142 | 33.9622641509434
[NAME] | [NAME] | 2560 | 265.798 | 1.019 | 1.005 | 1 | 545 | 3 | 3 | 2751 | 0 | 5312 | 0.01882530120481928 | 0.0390625 | 0.03904724716907458
[NAME] | 6-phosphogluconate dehydrogenase, C-terminal domain | 268 | 230.25 | 1.228 | 1.224 | 1 | 345 | 3 | 2 | 1513 | 0 | 1782 | 0.05611672278338946 | 0.3731343283582089 | 0.3717472118959108
Ets | Ets-domain | 742 | 396.425 | 1.559 | 1.542 | 1 | 669 | 3 | 3 | 0 | 1 | 743 | 0.1345895020188425 | 0.1347708894878706 | 0.1345895020188425
NAD_binding_2 | NAD binding domain of 6-phosphogluconate dehydrogenase | 150 | 419.18 | 1.567 | 1.547 | 1 | 345 | 3 | 2 | 4201 | 0 | 4352 | 0.02297794117647059 | 0.6666666666666667 | 0.6622516556291391
Gal-bind_lectin | Galactoside-binding lectin | 541 | 272.919 | 1.695 | 1.061 | 1 | 703 | 3 | 2 | 21 | 0 | 563 | 0.1776198934280639 | 0.1848428835489834 | 0.1845018450184502
S-antigen | S-antigen protein | 12 | 393.083 | 1.833 | 1.167 | 1 | 456 | 3 | 2 | 9 | 0 | 22 | 4.545454545454546 | 8.333333333333332 | 7.692307692307693
BCS1_N | BCS1 N terminal | 39 | 405.179 | 1.974 | 1.949 | 1 | 508 | 3 | 2 | 167 | 0 | 207 | 0.4830917874396135 | 2.564102564102564 | 2.5
SAM_PNT | Sterile alpha motif (SAM)/Pointed domain | 347 | 450.271 | 1.997 | 1.919 | 1 | 669 | 3 | 3 | 0 | 1 | 348 | 0.2873563218390804 | 0.2881844380403458 | 0.2873563218390804
IMS | impB/mucB/samB family | 150 | 726.507 | 2.287 | 2.26 | 1 | 416 | 3 | 3 | 2635 | 0 | 2786 | 0.03589375448671931 | 0.6666666666666667 | 0.6622516556291391
MutS_I | MutS domain I | 277 | 483.675 | 2.303 | 2.264 | 1 | 1124 | 3 | 3 | 1535 | 0 | 1813 | 0.05515719801434087 | 0.3610108303249098 | 0.3597122302158274
IMS_C | impB/mucB/samB family C-terminal | 132 | 778.667 | 2.424 | 2.394 | 1 | 416 | 3 | 3 | 2219 | 0 | 2352 | 0.04251700680272109 | 0.7575757575757576 | 0.7518796992481203
Guanylate_cyc | Adenylate and Guanylate cyclase catalytic domain | 1016 | 905.39 | 2.549 | 2.224 | 3 | 1644 | 3 | 2 | 1895 | 0 | 2914 | 0.1029512697323267 | 0.2952755905511811 | 0.2944062806673209
[NAME] | Mitochondrial carrier protein | 2150 | 303.196 | 2.575 | 1.009 | 3 | 251.667 | 3 | 1 | 2064 | 0 | 4217 | 0.07114062129475932 | 0.1395348837209302 | 0.1393404551788203
TPP_enzyme_N | Thiamine pyrophosphate enzyme, N-terminal TPP binding domain | 64 | 538.469 | 2.766 | 2.766 | 1 | 553 | 3 | 3 | 5709 | 0 | 5774 | 0.0173190162798753 | 1.5625 | 1.538461538461539
TPP_enzyme_C | Thiamine pyrophosphate enzyme, C-terminal TPP binding domain | 60 | 546 | 2.783 | 2.783 | 1 | 553 | 3 | 3 | 7625 | 0 | 7686 | 0.01301066874837367 | 1.666666666666667 | 1.639344262295082
eRF1_1 | eRF1 domain 1 | 101 | 378.317 | 2.812 | 2.812 | 1 | 355 | 3 | 3 | 122 | 0 | 224 | 0.4464285714285714 | 0.9900990099009901 | 0.9803921568627451
UDPG_MGDP_dh_N | UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain | 51 | 444.392 | 2.843 | 2.843 | 8 | 390.125 | 3 | 3 | 2379 | 0 | 2438 | 0.3281378178835111 | 15.68627450980392 | 13.5593220338983
TPP_enzyme_M | Thiamine pyrophosphate enzyme, central domain | 60 | 562.033 | 2.867 | 2.867 | 1 | 553 | 3 | 3 | 4855 | 0 | 4916 | 0.02034174125305126 | 1.666666666666667 | 1.639344262295082
eRF1_2 | eRF1 domain 2 | 97 | 388.938 | 2.876 | 2.876 | 1 | 355 | 3 | 3 | 125 | 0 | 223 | 0.4484304932735426 | 1.030927835051546 | 1.020408163265306
UDPG_MGDP_dh_C | UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain | 48 | 465.938 | 2.917 | 2.917 | 8 | 390.125 | 3 | 3 | 2343 | 0 | 2399 | 0.3334722801167153 | 16.66666666666666 | 14.28571428571428
eRF1_3 | eRF1 domain 3 | 91 | 396.835 | 2.923 | 2.923 | 1 | 355 | 3 | 3 | 135 | 0 | 227 | 0.4405286343612335 | 1.098901098901099 | 1.08695652173913
DnaJ_CXXCXGXG | DnaJ central domain (4 repeats) | 176 | 416.347 | 2.932 | 2.915 | 2 | 380.5 | 3 | 3 | 2218 | 0 | 2396 | 0.08347245409015025 | 1.136363636363636 | 1.123595505617978
Topoisom_bac | DNA topoisomerase | 83 | 810 | 2.94 | 2.627 | 1 | 854 | 3 | 2 | 2914 | 0 | 2998 | 0.0333555703802535 | 1.204819277108434 | 1.19047619047619
ABC_membrane | ABC transporter transmembrane region | 1235 | 1027.33 | 2.999 | 1.899 | 1 | 705 | 3 | 3 | 12808 | 0 | 14044 | 0.007120478496154942 | 0.08097165991902834 | 0.08090614886731393
IMS_HHH | IMS family HHH motif | 27 | 711.667 | 3.074 | 3.074 | 1 | 416 | 3 | 3 | 1409 | 0 | 1437 | 0.06958942240779402 | 3.703703703703703 | 3.571428571428571
U-box | U-box domain | 214 | 633.953 | 3.103 | 2.019 | 1 | 1297 | 3 | 3 | 133 | 0 | 348 | 0.2873563218390804 | 0.4672897196261682 | 0.4651162790697674
PH | PH domain | 3051 | 844.701 | 3.103 | 2.491 | 1 | 501 | 3 | 3 | 720 | 0 | 3772 | 0.02651113467656416 | 0.03277613897082924 | 0.0327653997378768
MutS_V | MutS domain V | 233 | 690.124 | 3.129 | 3.064 | 1 | 1124 | 3 | 3 | 2869 | 0 | 3103 | 0.03222687721559781 | 0.4291845493562232 | 0.4273504273504274
Pkinase_C | Protein kinase C terminal domain | 855 | 753.54 | 3.338 | 2.861 | 1 | 501 | 3 | 3 | 314 | 0 | 1170 | 0.08547008547008547 | 0.1169590643274854 | 0.116822429906542
RQC | RQC domain | 67 | 1018.299 | 3.776 | 3.776 | 1 | 548 | 3 | 3 | 1007 | 0 | 1075 | 0.09302325581395349 | 1.492537313432836 | 1.470588235294118
AIRS | AIR synthase related protein, N-terminal domain | 164 | 796.061 | 3.854 | 3.488 | 2 | 553 | 3 | 2 | 4656 | 0 | 4822 | 0.04147656574035669 | 1.219512195121951 | 1.204819277108434
Cbl_N | CBL proto-oncogene N-terminal domain 1 | 68 | 685.368 | 3.985 | 3.971 | 1 | 390 | 3 | 3 | 0 | 0 | 69 | 1.449275362318841 | 1.470588235294118 | 1.449275362318841
MutS_III | MutS domain III | 163 | 898.018 | 4.086 | 3.994 | 1 | 1124 | 3 | 3 | 1754 | 0 | 1918 | 0.05213764337851929 | 0.6134969325153374 | 0.6097560975609756
Cbl_N2 | CBL proto-oncogene N-terminus, EF hand-like domain | 66 | 678.106 | 4.121 | 4.106 | 1 | 390 | 3 | 3 | 0 | 0 | 67 | 1.492537313432836 | 1.515151515151515 | 1.492537313432836
Cbl_N3 | CBL proto-oncogene N-terminus, SH2-like domain | 61 | 721.639 | 4.295 | 4.279 | 1 | 390 | 3 | 3 | 0 | 0 | 62 | 1.612903225806452 | 1.639344262295082 | 1.612903225806452
Response_reg | Response regulator receiver domain | 59 | 595.746 | 2.441 | 2.441 | 13 | 635.154 | 3.077 | 3.077 | 54164 | 0 | 54236 | 0.02396931927133269 | 22.03389830508474 | 18.05555555555555
Collagen | Collagen triple helix repeat (20 copies) | 2097 | 583.92 | 4.547 | 1.762 | 106 | 522.283 | 3.113 | 1.604 | 1213 | 1 | 3416 | 3.10304449648712 | 5.054840247973296 | 4.811620517476169
Myc-LZ | Myc leucine zipper domain | 705 | 200.332 | 3.003 | 2.996 | 15 | 431.467 | 3.133 | 3.067 | 0 | 6 | 720 | 2.083333333333333 | 2.127659574468085 | 2.083333333333333
Sushi | Sushi domain (SCR repeat) | 1507 | 746.745 | 6.064 | 2.358 | 128 | 301.945 | 3.266 | 1 | 0 | 4 | 1635 | 7.82874617737003 | 8.49369608493696 | 7.82874617737003
OTU | OTU-like cysteine protease | 295 | 619.573 | 1.546 | 1.278 | 92 | 2569.457 | 3.293 | 3.293 | 156 | 3 | 543 | 16.94290976058932 | 31.1864406779661 | 23.77260981912145
Glyco_hydro_2_N | Glycosyl hydrolases family 2, sugar binding domain | 94 | 674.011 | 2.287 | 2.287 | 2 | 814 | 3.5 | 3.5 | 2038 | 0 | 2134 | 0.09372071227741331 | 2.127659574468085 | 2.083333333333333
Glyco_hydro_2_C | Glycosyl hydrolases family 2, [NAME] barrel domain | 90 | 600.789 | 2.344 | 2.344 | 2 | 814 | 3.5 | 3.5 | 1715 | 0 | 1807 | 0.1106806862202546 | 2.222222222222222 | 2.173913043478261
Glyco_hydro_2 | domain | 56 | 674.696 | 2.893 | 2.893 | 2 | 814 | 3.5 | 3.5 | 1803 | 0 | 1861 | 0.107469102632993 | 3.571428571428571 | 3.448275862068965
[NAME] | Kelch motif | 1441 | 571.206 | 4.693 | 2.409 | 212 | 358.764 | 3.528 | 2.071 | 507 | 3 | 2160 | 9.814814814814815 | 14.71200555170021 | 12.82516636418633
Ribosomal_S27 | Ribosomal protein S27a | 117 | 145.385 | 1.821 | 1.812 | 14 | 610.643 | 3.571 | 3.571 | 61 | 0 | 192 | 7.291666666666667 | 11.96581196581197 | 10.68702290076336
Gag_MA | Matrix protein (MA), p15 | 27 | 734.296 | 3.667 | 3.481 | 133 | 710.481 | 3.609 | 3.609 | 0 | 4 | 160 | 83.125 | 492.5925925925926 | 83.125
[NAME] | [NAME] core shell protein | 26 | 784.269 | 3.731 | 3.538 | 122 | 759.311 | 3.779 | 3.779 | 0 | 3 | 148 | 82.43243243243244 | 469.2307692307692 | 82.43243243243244
zf-CCHC | Zinc knuckle | 546 | 470.438 | 3.161 | 1.839 | 11652 | 347.45 | 3.865 | 3.08 | 419 | 2 | 12617 | 92.35158912578268 | 2134.065934065934 | 95.5238563698967
BACK | BTB And C-terminal Kelch | 1622 | 536.113 | 4.059 | 2.473 | 161 | 407.366 | 3.882 | 2.416 | 0 | 3 | 1783 | 9.029725182277062 | 9.926017262638718 | 9.029725182277062
2OG-FeII_Oxy | 2OG-Fe(II) oxygenase superfamily | 674 | 468.153 | 1.55 | 1.528 | 64 | 1532.078 | 3.891 | 3.875 | 1919 | 0 | 2657 | 2.408731652239368 | 9.495548961424333 | 8.672086720867208
BTB | BTB/POZ domain | 3375 | 573.052 | 2.891 | 1.952 | 162 | 444.333 | 3.957 | 2.432 | 561 | 3 | 4098 | 3.953147877013177 | 4.8 | 4.580152671755725
PAS_3 | PAS fold | 993 | 674.481 | 2.175 | 2.162 | 2 | 587 | 4 | 4 | 5198 | 0 | 6193 | 0.03229452607782981 | 0.2014098690835851 | 0.2010050251256282
Myb_DNA-binding | Myb-like DNA-binding domain | 523 | 657.532 | 2.281 | 1.774 | 1 | 382 | 4 | 3 | 621 | 1 | 1145 | 0.08733624454148471 | 0.1912045889101338 | 0.1908396946564885
E1-E2_ATPase | E1-E2 ATPase | 1160 | 897.234 | 2.866 | 2.675 | 2 | 870.5 | 4 | 4 | 7725 | 0 | 8887 | 0.02250478226623157 | 0.1724137931034483 | 0.1721170395869191
Cation_ATPase_C | Cation transporting ATPase, C-terminus | 583 | 912.861 | 3.581 | 3.552 | 2 | 870.5 | 4 | 4 | 1968 | 0 | 2553 | 0.07833920877399138 | 0.3430531732418525 | 0.3418803418803419
F_actin_bind | F-actin binding | 28 | 1083.036 | 3.714 | 3.679 | 2 | 863.5 | 4 | 4 | 0 | 0 | 30 | 6.666666666666667 | 7.142857142857142 | 6.666666666666667
Cation_ATPase_N | Cation transporter/ATPase, N-terminus | 529 | 944.9 | 3.836 | 3.807 | 2 | 870.5 | 4 | 4 | 2370 | 0 | 2901 | 0.06894174422612892 | 0.3780718336483932 | 0.3766478342749529
CDC48_2 | Cell division protein 48 (CDC48), domain 2 | 114 | 710.053 | 4.053 | 3.158 | 1 | 690 | 4 | 3 | 129 | 0 | 244 | 0.4098360655737705 | 0.8771929824561403 | 0.8695652173913043
CDC48_N | Cell division protein 48 (CDC48), N-terminal domain | 107 | 723.131 | 4.14 | 3.224 | 1 | 690 | 4 | 3 | 165 | 0 | 273 | 0.3663003663003663 | 0.9345794392523363 | 0.9259259259259258
BNR | BNR/Asp-box repeat | 72 | 910.986 | 5.389 | 1.403 | 11 | 511.273 | 4 | 1.364 | 1557 | 0 | 1640 | 0.6707317073170732 | 15.27777777777778 | 13.25301204819277
Retro_M | Retroviral M domain | 107 | 309.617 | 1.393 | 1.346 | 50 | 629.62 | 4.04 | 3.48 | 0 | 9 | 157 | 31.84713375796178 | 46.72897196261682 | 31.84713375796178
AIG1 | [NAME] family | 172 | 319.843 | 1.145 | 1.012 | 73 | 1507.301 | 4.151 | 4.068 | 82 | 0 | 327 | 22.32415902140673 | 42.44186046511628 | 29.79591836734694
HisKA | His Kinase A (phosphoacceptor) domain | 7 | 433.429 | 2.429 | 2.429 | 6 | 785.333 | 4.167 | 4.167 | 30623 | 0 | 30636 | 0.01958480219349784 | 85.71428571428571 | 46.15384615384615
Laminin_EGF | Laminin EGF-like (Domains III and V) | 774 | 1269.03 | 8.845 | 2.924 | 8 | 947 | 4.25 | 1 | 1 | 1 | 783 | 1.021711366538953 | 1.03359173126615 | 1.023017902813299
Gag_p12 | Gag polyprotein, inner coat protein p12 | 14 | 688.857 | 3.929 | 3.929 | 77 | 777.909 | 4.364 | 4.364 | 0 | 0 | 91 | 84.61538461538461 | 550 | 84.61538461538461
DUF1388 | Repeat of unknown function (DUF1388) | 8 | 844.625 | 9.125 | 1.625 | 27 | 229.963 | 4.593 | 1 | 18 | 0 | 53 | 50.9433962264151 | 337.5 | 77.14285714285715
Gag_p10 | Retroviral GAG p10 protein | 38 | 556.158 | 3.421 | 2.711 | 39 | 780.769 | 4.641 | 4.256 | 0 | 1 | 77 | 50.64935064935064 | 102.6315789473684 | 50.64935064935064
GAF | GAF domain | 162 | 816.833 | 2.667 | 1.901 | 2 | 924 | 5 | 5 | 6146 | 0 | 6310 | 0.03169572107765452 | 1.234567901234568 | 1.219512195121951
PI3Ka | Phosphoinositide 3-kinase family, accessory domain (PIK domain) | 216 | 1258.421 | 4.051 | 3.968 | 1 | 1083 | 5 | 5 | 127 | 0 | 344 | 0.2906976744186047 | 0.4629629629629629 | 0.4608294930875576
PI3K_C2 | Phosphoinositide 3-kinase C2 | 173 | 1152.358 | 4.59 | 4.486 | 1 | 1083 | 5 | 5 | 61 | 0 | 235 | 0.425531914893617 | 0.5780346820809248 | 0.5747126436781609
PI3K_p85B | PI3-kinase family, p85-binding domain | 74 | 964.797 | 4.649 | 4.608 | 1 | 1083 | 5 | 5 | 0 | 0 | 75 | 1.333333333333333 | 1.351351351351351 | 1.333333333333333
PI3K_rbd | PI3-kinase family, ras-binding domain | 134 | 1191.5 | 4.918 | 4.799 | 1 | 1083 | 5 | 5 | 0 | 0 | 135 | 0.7407407407407408 | 0.7462686567164178 | 0.7407407407407408
Sel1 | Sel1 repeat | 176 | 581.057 | 5.017 | 1.25 | 3 | 552.333 | 5.667 | 1 | 3051 | 0 | 3230 | 0.09287925696594426 | 1.704545454545454 | 1.675977653631285
NC | NC domain | 115 | 206.27 | 1.017 | 1.017 | 3 | 2134 | 6 | 5 | 114 | 3 | 232 | 1.293103448275862 | 2.608695652173913 | 2.542372881355933
Kelch_2 | Kelch motif | 220 | 735.382 | 3.368 | 2.173 | 3 | 547.667 | 6 | 4 | 135 | 0 | 358 | 0.8379888268156425 | 1.363636363636364 | 1.345291479820628
NODP | NOTCH protein | 89 | 1953.775 | 25.079 | 6.382 | 4 | 506.75 | 6 | 2 | 0 | 0 | 93 | 4.301075268817205 | 4.49438202247191 | 4.301075268817205
RnaseH | RNase H | 152 | 591.632 | 3.059 | 3.007 | 4314 | 840.78 | 6.532 | 6.49 | 2114 | 4 | 6580 | 65.56231003039514 | 2838.157894736842 | 96.59650694133452
C_tripleX | Cysteine rich repeat | 68 | 674.074 | 14.265 | 1 | 1 | 125 | 7 | 1 | 0 | 0 | 69 | 1.449275362318841 | 1.470588235294118 | 1.449275362318841
Macro | Macro domain | 212 | 520.722 | 1.561 | 1.358 | 601 | 3476.724 | 7.546 | 7.414 | 824 | 37 | 1637 | 36.71350030543677 | 283.4905660377358 | 73.92373923739237
FtsJ | FtsJ-like methyltransferase | 204 | 507.686 | 1.52 | 1.515 | 2146 | 3224.883 | 13.972 | 13.972 | 1941 | 30 | 4291 | 50.01165229550222 | 1051.960784313726 | 91.31914893617021