Spreadsheet: f664138f-d3b0-4c1a-a3c7-ed7935db121b
Sheet: Sheet1

Table S5. Proteins up-regulated in PDAC and/or PanIN mouse plasma. | Unnamed: 1 | Unnamed: 2 | Unnamed: 3 | Unnamed: 4 | Unnamed: 5 | Unnamed: 6 | Unnamed: 7 | Unnamed: 8 | Unnamed: 9 | Unnamed: 10 | Unnamed: 11 | Unnamed: 12 | Unnamed: 13 | Unnamed: 14 | Unnamed: 15 | Unnamed: 16
 |  |  |  |  |  | PROTEOMIC QUANTITATION |  |  |  |  |  | Gene expression data
 |  |  |  |  |  | PDAC (ADVANCED STAGE) |  |  | PanIN (EARLY STAGE) |  |  | [NAME] | HUMAN*
 | IPI | [NAME] | Human Ortholog | Uniprot _Acession | Description | Quant. Events | Protein Average Ratio | Probability | Quant. Events | Protein Average Ratio | Probability | Cancer / Normal | Cancer / Normal | Pancreatitis/ Normal | IN MOUSE LIVER# | Acute Phase Reactant, Complement system or coagulation&
1 | IPI00121271 | 0610011F06Rik | MGC13114 | Q9DCS2, | adult male kidney cdna, riken full-length enriched library,clone:0610011f06 product:hypothetical s-adenosyl-l-methionine-dependent methyltransferases structure containing protein, full insertsequence. | 1 | 3.20049183366528 | 0.007 |  |  |  | 0.31297863764611 |  |  | yes
2 | IPI00471091 | 0610012D14Rik |  | Q9DCQ2, | putative l-aspartate dehydrogenase. | 1 | cancer only |  |  |  |  | 0.28634361233482 |  |  | yes
3 | IPI00316314 | 1600020H07Rik |  | Q9QXE0, | 2-hydroxyphytanoyl-coa lyase. | 1 | cancer only |  |  |  |  | 1.3225469728613 |  |  | yes
4 | [NAME] | 1810009J06Rik |  | Q7TT42,Q9CPN7, | 10 day old male pancreas cdna, riken full-length enriched library,clone:1810009j06 product:trypsin iv. | 38 | 3.29913842910679 | <0.001 |  |  |  | 0.93326778916372
5 | IPI00131674 | 2210010C04Rik |  | Q9CPN9,Q9D7Y7, | adult male small intestine cdna, riken full-length enriched library,clone:2010206b10 product:[NAME], cationic. | 23 | 3.04109956030122 | 0.001250076 | 1 | cancer only |  | 0.14958143212424
6 | IPI00461384 | 2310075M15Rik |  | Q3UQ28,Q80U60, | 15 days embryo head cdna, riken full-length enriched library,clone:d930033o22 product:myeloblast kiaa0230 homolog. | 1 | cancer only |  |  |  |  | 6.9462943719656
7 | IPI00154054 | [NAME] | [NAME] | Q8QZT1, | acetyl-coa acetyltransferase, mitochondrial precursor. | 1 | 2.82671066294525 | 0.01 |  |  |  | 0.394832937739638 | 0.3011486065354821 | 0.3888300240406019 | yes
8 | IPI00228253 | Acat2 | ACAT2 | [NAME], | acetyl-coa acetyltransferase, cytosolic. | 8 | 3.84355933249023 | 0.026524251 |  |  |  | 0.959114583333333 | 0.9882782475019215 | 0.9308224442736357 | yes
9 | IPI00380751 | Adamtsl2 | ADAMTSL2 | Q3U0C8,Q6A040,Q7TSK7,Q9D201, | activated spleen cdna, riken full-length enriched library,clone:f830111o22 product:tsp1-repeats containing protein, full insertsequence. | 1 | 3.17079636692627 | 0.007 |  |  |  | 1.149171428571
10 | IPI00128738 | Agxt2 | AGXT2 | [NAME], | adult male liver tumor cdna, riken full-length enriched library,clone:c730034d07 product:alanine--glyoxylate aminotransferase 2,mitochondrial (ec 2.6.1.44) (agt 2) (beta-alanine-pyruvateaminotransferase) (beta- [NAME]) homolog. | 1 | cancer only |  |  |  |  | 0.634146341463415 |  |  | yes
11 | IPI00221769 | Ak3 | AK3 | Q9WTP7, | gtp:amp phosphotransferase mitochondrial. | 1 | cancer only |  |  |  |  | 0.32236395237 | 4.897142857142857 | 3.575 | yes
12 | IPI00131695 | Alb1 | ALB | P07724, | serum albumin precursor. | 615 | 3.64212686781732 | <0.001 | 66 | 0.611895222743904 | <0.001 | 0.24247748737964 | 0.1457183731861844 | 0.1337625178826896 | yes | acute-phase
13 | IPI00121378 | Alcam | ALCAM | Q61490, | cd166 antigen precursor. | 4 | 2.7576 | 0.03197 |  |  |  | 2.8173382475127 | 1.071868809156945 | 1.052388289676425
14 | IPI00626662 | Aldh1a1 | ALDH1A1 |  | retinal dehydrogenase 1 | 1 | 8.83162323394493 | 0.001 |  |  |  | 0.2252515826495 | 0.4763765919544814 | 0.8499441652707984 | yes
15 | IPI00127206 | Aldob | ALDOB | Q91Y97, | fructose-bisphosphate aldolase b. | 43 | 3.12442665290821 | <0.001 | 1 | 0.657398179673846 | 0.927 | 0.158482142857143 | 2.738984941438929 | 1.456218627997769 | yes
16 | IPI00127352 | Ambp | AMBP | Q07456, | ambp protein precursor. | 294 | 2.58135684854126 | <0.001 | 208 | 2.01124462219782 | <0.001 | 1.655286669464 | 0.4400166475913016 | 0.3658048069919884 |  | acute-phase
17 | IPI00133544 | Amy2 | AMY2A | P00688, | pancreatic alpha-amylase precursor. | 40 | 4.48922215806467 | <0.001 | 14 | 8.28927153332115 | <0.001 | 0.8493351163393 |  |  | yes
18 | IPI00121240 | Apon |  | Q8BUM4,Q8VC08, | apolipoprotein n | 2 | 3.27857702289525 | 0.499999999 | 44 | 2.05768275708465 | <0.001 | 0.3634644864227
19 | [NAME] | Asrgl1 | ASRGL1 | Q8C0M9,Q91WC8,Q9CVX3, | adult male testis cdna, riken full-length enriched library,clone:4933423n16 product:asparaginase-like sperm autoantigen homolog. | 1 | 2.77836973585782 | 0.01 |  |  |  | 0.351621745898 | 0.7824556256417778 | 0.8078700308053396
20 | IPI00109966 | B2m | B2M | P01887, | beta-2-microglobulin precursor. | 14 | 0.874230517754743 | 0.731944088 | 16 | 1.53027356916528 | <0.001 | 2.295249518964 | 1.869854265914929 | 1.787333129373601 | yes
21 | IPI00130950 | [NAME] | BHMT | O35490, | betaine--[NAME]. | 15 | 3.11762208925494 | 0.009551513 |  |  |  | 0.17728729831589 | 0.3611654282362143 | 0.458887368009386 | yes
22 | IPI00624640 | [NAME] | BTD |  | 59 kda protein. (biotinidase) | 1 | 1.37750873782406 | 0.089 | 1 | 3.72901769169509 | 0.004 | 1.3513513513514 | 0.3535919752175837 | 0.5307567487830064
23 | IPI00653596 | C1qb | C1QB | Q3U6I5,Q3U793,Q3US82, | bone marrow macrophage cdna, riken full-length enriched library,clone:i830123n03 product:complement component 1, q subcomponent, betapolypeptide, full insert sequence. | 10 | 3.25551720443092 | 0.046999389 | 18 | 2.0163699838255 | <0.001 | 5.252464171123 | 1.056306822522729 | 2.460214684085873 |  | complement
24 | IPI00407502 | C1r | C1R | Q8CG16, | [NAME] subcomponent precursor. | 64 | 1.61814546942949 | 0.005131922 | 52 | 0.672787915069047 | <0.001 | 0.744183433921 | 1.736990635823321 | 2.90107752170009 |  | complement
25 | IPI00653675 | C1s |  |  | complement component 1, s subcomponent | 1 | cancer only |  | 26 | 0.573496331713675 | <0.001 |  |  |  |  | complement
26 | IPI00626894 | Cacna2d2 | CACNA2D2 | Q3TPT9,Q3TSS6,Q9R142, | adult male hippocampus cdna, riken full-length enriched library,clone:c630004d13 product:calcium channel, voltage-dependent, alpha2/delta subunit 2, full insert sequence.. | 1 | cancer only |  |  |  |  | 0.9367886759494 | 0.6356382978723404 | 2.368351063829787
27 | IPI00137331 | Cap1 | CAP1 | P40124, | [NAME] protein 1. | 1 | 3.39974262670945 | 0.006 |  |  |  | 4.425675675675675 |  |  | yes
28 | IPI00312058 | Cat | CAT | [NAME], | catalase. | 30 | 2.27295913874011 | 0.002566914 | 3 | 1.04233076236294 | 0.859971992 | 1.71487758945386 | 0.6824817518248175 | 0.8765967153284671 | yes
29 | IPI00129384 | Ccl8 |  | Q9Z121, | small inducible cytokine a8 precursor. | 31 | 1.56054218245471 | 0.060575733 | 8 | 1.57499331096132 | <0.001 | 1.8753862698
30 | IPI00262127 | Cd248 | CD248 | Q3UMV6,Q91V98,Q91ZV1, | cd164 sialomucin-like 1, full insertsequence. | 4 | 1.32221119801886 | 0.715935154 | 1 | 1.77328325573324 | 0.036 | 6.3884826325411
31 | IPI00316045 | Cd5l | CD5L | Q9QWK4, | cd5 antigen-like precursor. | 70 | 2.72580703357839 | <0.001 | 53 | 2.11156365983933 | <0.001 | 0.254156448569 | 0.582018927444795 | 0.6597003154574133
32 | IPI00399798 | Cd97 | CD97 | Q9Z0M6-1, | splice isoform 1 of cd97 antigen precursor. | 5 | 1.18516589543853 | 0.814902011 | 1 | 2.61294684949013 | 0.013 | 9.891357421875 | 4.035800677310111 | 3.704039671020803
33 | [NAME] | Cdh1 | CDH1 | P09803, | epithelial-cadherin precursor. |  |  |  | 1 | 1.96636946241755 | 0.026 | 2.6179775288989 | 1.895460358056266 | 0.7552749360613811
34 | [NAME] | Cfh | CFH | Q61408, | complement factor h-related protein. | 31 | 1.60261634850167 | 0.144065929 | 11 | 3.65622771674204 | 0.008013498 | 4.1117493472585 |  |  | yes | complement
35 | IPI00130010 | Cfh | CFH | P06909, | complement factor h precursor. | 6012 | 1.67164464690312 | <0.001 | 3012 | 1.0728625041728 | <0.001 | 4.1117493472585 |  |  | yes | complement
36 | IPI00121050 | Cfhl1 |  | Q61406, | complement factor h-related protein. | 19 | 2.09785575189245 | 0.041108586 | 1 | 7.54980842059565 | 0.001 | 0.27591248759124 |  |  |  | complement
37 | IPI00128682 | Clec11a | CLEC11A | O88200, | c-type lectin domain family 11 member a precursor. | 2 | 1.21870970394937 | 0.874334084 | 1 | 1.61187531623969 | 0.049 | 0.4211629384148
38 | IPI00330594 | Clec4f | CLEC4F | P70194, | c-type lectin domain family 4 member f. | 1 | 2.49796746637421 | 0.014 |  |  |  | 0.8659688825152 |  |  | yes
39 | IPI00132377 | Clps | CLPS | Q9CQC2, | colipase precursor. | 1 | cancer only |  |  |  |  | 0.19823253989818 | 0.1604245238320857 | 0.1790396095896901
40 | IPI00320420 | Clu | CLU | Q06890, | clusterin precursor. | 136 | 2.5870716894307 | <0.001 | 71 | 1.3698795789663 | <0.001 | 0.9865978959741 | 1.139819587628866 | 3.770618556701031 | yes
41 | IPI00648224 | Col15a1 | COL15A1 | O35206, | PROCOLLAGEN TYPE XV | 1 | 1.78755826860375 | 0.035 |  |  |  | 13.67417162276975 | 1.244402594685081 | 1.145244821092279
42 | IPI00131476 | Col18a1 | COL18A1 | P39061-1, | splice isoform 2 of collagen alpha 1(xviii) chain precursor. | 1 | cancer only |  |  |  |  | 13.67417162276975 | 1.244402594685081 | 1.145244821092279
43 | IPI00117831 | Cp | CP | [NAME], | ceruloplasmin precursor. | 30 | 2.56930440864736 | 0.002566914 | 417 | 0.82206344235637 | <0.001 | 4.224161912654 | 2.015893197711379 | 0.6452638270820089 | yes | acute-phase
44 | IPI00322594 | Ctgf | CTGF | P29268, | connective tissue growth factor precursor. | 21 | 2.01396421816061 | 0.032347423 | 6 | 0.761580198847178 | 0.011409293 | 89.598937178265 | 1.211456774141349 | 3.878474048302925
45 | IPI00309363 | Ctla2a |  | P12399, | cytotoxic t lymphocyte-associated protein 2 alpha precursor. | 1 | 3.04506419982356 | 0.008 | 2 | 0.905171710911281 | 0.590334471 | 54.37987616997
46 | IPI00315696 | Ctrb1 | CTRB1 | Q9CR35,Q9D8X8,Q9DC86, | adult male stomach cdna, riken full-length enriched library,clone:2210414j01 product:[NAME] | 41 | 6.10868566297794 | <0.001 | 40 | 9.07952213592394 | <0.001 | 0.297972517321515 | 0.2775120325492086 | 0.2590154245015691
47 | IPI00113517 | Ctsb | CTSB | P10605, | cathepsin b precursor. | 44 | 1.49263002823616 | 0.04163233 | 1 | 6.8188415073432 | 0.001 | 1.916794954561255 | 2.55482302333193 | 2.984254453640062 | yes
48 | IPI00309520 | Ctss | CTSS | O70370, | bone marrow macrophage cdna, riken full-length enriched library,clone:i830001d23 product:[NAME], full insert sequence. | 5 | 2.375 | 0.0166 |  |  |  | 16.786173633445 | 3.442252624880688 | 2.795657015590201
49 | IPI00648885 | Cxcl16 | CXCL16 | Q5F2D6, | chemokine. | 1 | 2.81508725416073 | 0.01 |  |  |  | 3.237226277372263
50 | IPI00154044 | D9Ucla1 |  | Q3UD27,Q8QZR4, | bone marrow macrophage cdna, riken full-length enriched library,clone:i830001f17 product:similar to out at first protein (hypotheticalprotein), full insert sequence. | 4 | 1.15328931736293 | 0.854270329 | 1 | 1.89074078322642 | 0.031 | 1.7572239853149
51 | IPI00459280 | Dcps | DCPS | Q9DAR7, | scavenger mrna decapping enzyme dcps. | 1 | cancer only |  |  |  |  | 0.9347263854479 | 1.429283250287466 | 1.018876964354159
52 | IPI00118817 | Ddx26 |  | Q61204, | egf repeat transmembrane protein. | 8 | 0.875502522620713 | 0.809765586 | 1 | 10 |  | 5.584672435157 |  |  | yes
53 | IPI00318577 | Dpys | DPYS | Q9EQF5, | dihydropyrimidinase. | 1 | cancer only |  |  |  |  | 0.18291153415454 | 0.93952802359882 | 1.347345132743363 | yes
54 | IPI00454049 | Echs1 | ECHS1 | [NAME], | enoyl-coa hydratase, mitochondrial precursor. | 1 | cancer only |  |  |  |  | 0.8937692447247 | 0.7748901098901099 | 0.806298076923077 | yes
55 | IPI00126055 | Efemp2 | EFEMP2 | Q9WVJ9, | egf-containing fibulin-like extracellular matrix protein 2 precursor. | 2 | 1.16253188867156 | 0.936548965 | 1 | 3.05989879562488 | 0.008 | 29.95254794525 | 2.09987917841321 | 3.437978252114378
56 | [NAME] | Efna1 | EFNA1 | P52793, | [NAME] precursor. | 3 | 0.957197207650753 | 0.992929109 | 1 | 10 |  | 2.6167153996114 | 2.258078097042417 | 1.915219450584149
57 | IPI00171983 | Ela1 | ELA1 | [NAME], | ela1 protein. | 7 | 2.25690595521632 | 0.17211821 | 1 | cancer only |  | 0.825115879983614
58 | [NAME] | Etfb | ETFB | Q9DCW4, | electron transferring flavoprotein, beta polypeptide. | 1 | 1.9539838552852 | 0.026 |  |  |  | 0.37929525783387 | 2.247998398718975 | 1.871196957566053 | yes
59 | IPI00121322 | Etfdh | ETFDH | Q921G7, | electron transfer flavoprotein-ubiquinone oxidoreductase,mitochondrial precursor. | 1 | cancer only |  |  |  |  | 1.6664944458796 | 0.7667057444314186 | 0.7919109026963658 | yes
60 | IPI00307890 | F7 | F7 | P70375, | coagulation factor vii precursor. | 8 | 0.733425267494695 | 0.567413497 | 25 | 1.50797580138867 | <0.001 | 3.42137565327 | 0.5588512241054614 | 0.548728813559322 |  | coagulation
61 | IPI00348266 | F9 | F9 | P16294, | adult male liver tumor cdna, riken full-length enriched library,clone:c730002c14 product:coagulation factor ix, full insert sequence. | 21 | 1.03194183177799 | 0.882267023 | 16 | 1.74007458543719 | 0.008972737 | 1.1818181818182 | 1.096228868660598 | 0.6849804941482445 |  | coagulation
62 | IPI00230492 | Fbln2 | FBLN2 | P37889-2, | splice isoform 2 of fibulin-2 precursor. | 19 | 2.6271755437538 | 0.007685412 |  |  |  | 5.683326162387 | 4.065855704697987 | 8.176698825503356
63 | IPI00115522 | Fga | FGA | Q08284,Q99K47, | fibrinogen, alpha polypeptide. | 306 | 2.31741342739081 | <0.001 | 209 | 1.02324778702468 | <0.001 | 7.628654977623 | 0.7882882882882882 | 0.7882882882882882 | yes | acute-phase
64 | [NAME] | [NAME] | FGB | Q8K0E8, | fibrinogen beta chain precursor. | 585 | 1.71691152442971 | <0.001 | 1086 | 0.802300714409301 | <0.001 | 3.945 | 1.100275988960442 | 0.8178472861085557 | yes | acute-phase
65 | IPI00122312 | Fgg | FGG | Q8VCM7, | adult male liver tumor cdna, riken full-length enriched library,clone:c730002j02 product:fibrinogen, gamma polypeptide, full insertsequence. | 398 | 2.01084144090295 | <0.001 | 714 | 0.796885297721923 | <0.001 | 1.3258414464534 | 0.988898756660746 | 0.1756216696269982 | yes | acute-phase
66 | IPI00121312 | Fgl1 | FGL1 | Q71KU9,Q8VC25, | mfire1. | 1 | 3.08579100947312 | 0.008 |  |  |  | 1.463796774194 | 0.2287900054843418 | 0.04063525409234144
67 | IPI00352163 | Fn1 | FN1 | Q3TBB4,Q3TCF1,Q9Z1Z7, | nod-derived cd11c +ve dendritic cells cdna, riken full-length enrichedlibrary, clone:f630118j10 product:fibronectin 1, full insert sequence. | 347 | 2.11183291216095 | <0.001 | 758 | 1.03905635226531 | <0.001 | 25.24684559452524 | 5.820325482024636 | 5.134742700393005 | yes | acute-phase
68 | IPI00652813 | Fn1 | FN1 | Q3UHL6,Q8R3F3, | cdna, riken full-length enriched library, clone:m5c1012h16product:fibronectin 1, full insert sequence. | 1497 | 1.84434820711798 | <0.001 | 1272 | 1.10154166838871 | <0.001 | 25.24684559452524 | 5.820325482024636 | 5.134742700393005 | yes | acute-phase
69 | IPI00124707 | Fstl1 | FSTL1 | Q62356, | follistatin-related protein 1 precursor. | 5 | 6.45 | 0.005 | 4 | 1.09444110994447 | 0.351683195 | 12.71233389481565 | 2.3392023633678 | 3.435583456425407
70 | IPI00273646 | Gapdh | GAPDH | P16858, | glyceraldehyde-3-phosphate dehydrogenase. | 1 | 2.26777130272202 | 0.017 |  |  |  |  |  |  | yes
71 | IPI00473475 | Gchfr | GCHFR | P99025, | gtp cyclohydrolase i feedback regulatory protein. | 1 | cancer only |  |  |  |  | 0.6536881676518 | 1.206234344558864 | 1.134845532980796
72 | IPI00458508 | Gda | GDA | Q8BRJ7, | 10 days neonate cortex cdna, riken full-length enriched library,clone:a830088f01 product:guanine deaminase, full insert sequence. | 1 | 5.2419259001735 | 0.004 |  |  |  | 0.8492958993681
73 | IPI00133076 | Gkn1 | GKN1 | Q9CR36, | gastrokine-1 precursor. | 4 | 1.58123051105954 | 0.562028151 | 1 | cancer only |  | 12.914141414141
74 | IPI00331528 | Glrx1 |  | Q9QUH0, | glutaredoxin-1. | 1 | 1.94904182111915 | 0.027 |  |  |  | 1.977123526 |  |  | yes
75 | IPI00117312 | Got2 | GOT2 | P05202, | aspartate aminotransferase, mitochondrial precursor. | 1 | 2.28172962636506 | 0.017 |  |  |  | 0.293518518518519 | 1.035261206167458 | 0.7853425281374017 | yes
76 | IPI00124640 | Grn | GRN | [NAME], | osteoclast-like cell cdna, riken full-length enriched library,clone:i420031m06 product:granulin, full insert sequence. | 210 | 2.35917184521801 | <0.001 | 117 | 1.23779078041543 | <0.001 | 1.9173586462635 | 1.565758513931888 | 1.450386996904025 | yes
77 | IPI00626132 | Hadh2 | [NAME] | Q99N15,Q9CYT3, | 17beta-hydroxysteroid dehydrogenase type 10/short chain [NAME]-coa dehydrogenase. | 1 | cancer only |  |  |  |  | 0.738471673254282 | 1.394777127420081 | 1.232170193606484 | yes
78 | IPI00115866 | Hagh | HAGH | Q99KB8, | hydroxyacylglutathione hydrolase. | 1 | 2.52370834199662 | 0.014 |  |  |  | 0.374812842941 | 0.8506139154160982 | 1.034163256025466 | yes
79 | IPI00110291 | Hamp1 | HAMP | [NAME], | hepcidin precursor. | 1 | 1.75872868589734 | 0.037 | 1 | 0.962559308966061 | 0.478 | 0.19268797198474 | 0.9929341762737077 | 0.8161026403867608 |  | acute-phase
80 | IPI00409148 | Hp | HP | Q61646, | haptoglobin precursor. | 824 | 4.64705391089146 | <0.001 | 337 | 3.79048125193535 | <0.001 | 34.8775512482 | 0.5995670995670995 | 1.358585858585859 | yes | acute-phase
81 | IPI00128484 | Hpxn | HPX | Q91X72, | hemopexin precursor. | 5203 | 2.91106841655095 | <0.001 | 3519 | 2.03701137912363 | <0.001 | 0.77691658394161 |  |  | yes | acute-phase
82 | IPI00130640 | Hrsp12 | HRSP12 | P52760, | ribonuclease uk114. | 1 | 1.6987271816136 | 0.043 |  |  |  | 0.416941631584936 |  |  | yes
83 | IPI00128040 | Htra1 | HTRA1 | Q9R118, | serine protease htra1 precursor. | 1 | cancer only |  |  |  |  | 2.9237123427969
84 | IPI00122973 | Icam1 | ICAM1 | P13597-1, | splice isoform 1 of intercellular adhesion molecule 1 precursor. | 26 | 1.61 | 0.013 | 1 | 0.865659716955387 | 0.718 | 3.9151376146789 | 2.227991746905089 | 1.499656121045392
85 | IPI00135231 | Idh1 | IDH1 | O88844, | 0 day neonate lung cdna, riken full-length enriched library,clone:e030024j03 product:isocitrate dehydrogenase 1 (nadp+), soluble,full insert sequence. | 1 | cancer only |  |  |  |  | 3.2534545454 | 1.764296391202221 | 1.192002989536622 | yes
86 | IPI00112487 | Igfbp4 | IGFBP4 | P47879, | insulin-like growth factor binding protein 4 precursor. | 168 | 1.29197669131334 | <0.001 | 134 | 1.4996 | <0.001 | 37.49816735971 | 2.747381188664682 | 5.156315470283382
87 | IPI00136925 | Igj | IGJ | P01592, | immunoglobulin j chain precursor. | 19 | 2.10206813837501 | 0.027426868 | 8 | 1.13594973224253 | 0.047466153 | 1.995217678126 | 3.334491813407476 | 3.816265060240964 |  | acute-phase
88 | IPI00113879 | Il1rap | IL1RAP | [NAME], | splice isoform 2 of interleukin-1 receptor accessory proteinprecursor. | 1 | cancer only |  | 1 | cancer only |  | 0.398451113262343 | 6.394045534150613 | 4.885288966725044
89 | IPI00128358 | Insr | INSR | P15208, | insulin receptor precursor. | 1 | cancer only |  |  |  |  | 0.395619134458 | 0.7804370447450573 | 0.3642039542143601
90 | IPI00322867 | Itih1 | ITIH1 | Q61702, | [NAME] protein. | 4 | 0.896204192121814 | 0.890281855 | 25 | 1.6606228881113 | <0.001 | 0.341584158415842 | 0.997005988023952 | 1.004678143712575
91 | IPI00227834 | Itih2 | ITIH2 | Q61703, | 8 days embryo whole body cdna, riken full-length enriched library,clone:5730412l20 product:inter-alpha trypsin inhibitor, heavy chain 2,full insert sequence. | 32 | 2.08463241466672 | 0.005288747 | 3 | 2.04447732472906 | 0.205540161 | 0.286523477235 | 0.7078025477707007 | 0.6186305732484076 | yes | acute-phase
92 | IPI00312711 | Itih4 | ITIH4 | O54882,Q505P8,Q8C7G9,Q8C7K5,Q91W60, | pk-120. | 69 | 2.35438006148661 | <0.001 | 31 | 1.35561126984524 | <0.001 | 0.1817313284487 | 1.558603491271821 | 0.763715710723192 | yes | acute-phase
93 | IPI00656329 | Kng1 | KNG1 | Q32MX7, | kng1 protein. | 1 | cancer only |  | 854 | 1.40259568398635 | <0.001 | 1.884955752212 |  |  | yes | coagulation
94 | IPI00400202 | Kng2 |  | Q32MX9,Q6DMP4,Q6S9I0,Q6S9I3, | hmw kininogen-ii. | 267 | 1.5776063710505 | <0.001 | 170 | 1.33998636769181 | <0.001 |  |  |  |  | coagulation
95 | IPI00331436 | Lap3 | [NAME] | Q9CPY7, | lap3 protein. | 14 | 3.56635903961143 | 0.00696759 |  |  |  | 0.327687984988 | 2.682039781591264 | 1.913465288611544 | yes
96 | IPI00115941 | Lcn2 | LCN2 | P11672, | neutrophil gelatinase-associated lipocalin precursor. | 7 | 6.90473116287473 | 0.0089678 | 1 | cancer only |  | 39.7698198198 | 13.37703822507351 | 3.799502138465651
97 | IPI00110120 | Lims1 | LIMS1 | Q4ZJB3,Q9D7B2, | adult male tongue cdna, riken full-length enriched library,clone:2310016j22 product:pinch protein (particularly interesting newcys-his protein) homolog. | 1 | 2.16620191017752 | 0.019 |  |  |  | 16.25555555555556 | 0.8802821336356194 | 0.7614301908180615
98 | IPI00129250 | Lrg1 | [NAME] | Q91XL1, | leucine-rich alpha-2-glycoprotein precursor. | 188 | 2.94209626684283 | <0.001 | 75 | 1.95594509242728 | <0.001 | 1.32686956522
99 | IPI00124265 | Ltbp4 | LTBP4 | Q8K4G1-2, | splice isoform 2 of latent transforming growth factor beta bindingprotein 4 precursor. | 1 | cancer only |  |  |  |  | 2.1944267335 | 1.673175745118191 | 1.919064748201439
100 | IPI00317340 | [NAME] | LTF | Q5MJE7,Q8CBA0, | adult male bone cdna, riken full-length enriched library,clone:9830118d19 product:lactotransferrin, full insert sequence. | 61 | 2.26070164293674 | <0.001 |  |  |  | 16.99253731343284 | 5.743282787975525 | 0.9245810055865922
101 | IPI00399954 | Lyst | [NAME] | P97412-1, | splice isoform 1 of lysosomal trafficking regulator. |  |  |  | 1 | cancer only |  | 0.4423155321631
102 | IPI00107952 | [NAME] |  | P08905, | osteoclast-like cell cdna, riken full-length enriched library,clone:i420013m05 product:lysozyme, full insert sequence. | 35 | 2.71427827871513 | <0.001 | 16 | 1.41377055921036 | <0.001 | 14.24973147153598
103 | [NAME] | Lzp-s | LYZ | P17897, | lysozyme c type p precursor. | 4 | 3.22 | <0.001 | 1 | 1.14782243154013 | 0.21 | 33.28244869729 | 3.637131614429983 | 2.648523706006989
104 | IPI00230760 | Mb | MB | P04247, | myoglobin. | 29 | 1.22463127811917 | 0.375795952 | 19 | 1.63663601971752 | 0.002047199 | 0.1558951965655 | 0.6007280291211647 | 0.568408736349454 | yes
105 | IPI00113457 | Mbl2 | MBL2 | P41317, | mannose-binding protein c precursor. | 176 | 0.701403990352713 | <0.001 | 179 | 1.73466051823074 | <0.001 | 0.86877394636153 | 1 | 1 | yes | acute-phase
106 | IPI00310173 | Msh6 | MSH6 | Q61061,Q6GTK8,Q8C2N9,Q9CRH0, | muts homolog 6. | 1 | 2.28072492534542 | 0.017 |  |  |  | 3.243589743589744 | 0.9773869346733669 | 0.8793969849246231
107 | IPI00554926 | Mup1 |  | Q8JZT0, | mup1 protein. | 1 | cancer only |  | 4 | 0.145815511129832 | 0.003419691 | 0.138482632541133 |  |  | yes
108 | IPI00230665 | Ncam2 | NCAM2 | P13595-2, | splice isoform n-cam 140 of neural cell adhesion molecule 1, 180 kdaisoform precursor. | 1 | cancer only |  |  |  |  | 0.1567734866298 | 0.7714285714285715 | 1.011363636363636
109 | IPI00127417 | Nme2 | [NAME] | Q01768, | nucleoside diphosphate [NAME] | 3 | 1.03152532525382 | 0.929465438 | 1 | 8.48048723937662 | 0.001 | 0.7912155172 | 1.076563890793947 | 0.9684996570894924 | yes
110 | IPI00129186 | Npc2 | NPC2 | Q9Z0J0, | epididymal secretory protein e1 precursor. | 1 | 3.0852012126177 | 0.008 |  |  |  | 4.848182586644126 | 0.7883537471455263 | 1.216524807971767 | yes
111 | IPI00123996 | Nrp1 | NRP1 | P97333, | neuropilin-1 precursor. | 1 | 3.40401089511662 | 0.005 |  |  |  | 0.893784986364289 | 1.083801554094441 | 1.315481171548117
112 | IPI00134514 | Orm3 |  | Q63805, | alpha-1-acid glycoprotein 3 precursor. | 8 | 7.6515980404685 | 0.00403556 |  |  |  | 0.57346938775512 |  |  |  | acute-phase
113 | IPI00115973 | Pfc |  | P11680, | properdin precursor. | 396 | 1.58471006403722 | <0.001 | 405 | 1.04935529492355 | <0.001 | 9.419629837
114 | IPI00457898 | Pgam1 | PGAM1 | Q9DBJ1, | phosphoglycerate mutase 1. | 2 | 1.75344168687726 | 0.73080283 | 5 | 2.61599600445568 | <0.001 | 4.11285771866183 | 1.503366821504447 | 1.56731842569587 | yes
115 | IPI00165807 | Pglyrp2 | PGLYRP2 | Q8VCS0-1, | splice isoform 1 of n-acetylmuramoyl-l-alanine amidase precursor. | 133 | 2.38312604023348 | <0.001 | 149 | 0.969139045730172 | <0.001 | 0.316666666666667
116 | IPI00310059 | Pigr | PIGR | O70570, | [NAME] receptor precursor. | 26 | 2.04580720960639 | 0.024166286 |  |  |  | 1.996996996997 | 1.113449564134496 | 0.9805884184308842 | yes
117 | [NAME] | Piwil4 | PIWIL4 | Q8CGT6, | miwi 2 protein. | 2 | 1.03100110779787 | 0.936548965 | 1 | 1.84606117579108 | 0.032 | 0.36713927835
118 | IPI00118355 | Pnliprp1 | PNLIPRP1 | Q5BKQ4, | pancreatic lipase-related protein 1 precursor. | 1 | cancer only |  |  |  |  | 0.5585252869253 | 0.1153609301795631 | 0.1577775848645071
119 | IPI00554989 | Ppia | PPIA | P17742, | peptidyl-prolyl cis-trans [NAME] | 64 | 1.7792227930404 | <0.001 | 6 | 0.781599035520817 | 0.08975325 | 1.363738161911 | 2.324268432176106 | 1.617090621236109 | yes
120 | IPI00116254 | Prdx4 | PRDX4 | O08807, | peroxiredoxin 4. | 1 | 2.84196571076693 | 0.01 |  |  |  | 0.736686975431786 | 0.261948971872636 | 0.221935155141262 | yes
121 | IPI00656236 | Prg4 | PRG4 | Q9JM99-5, | splice isoform e of proteoglycan-4 precursor. | 1 | cancer only |  | 22 | 2.50842810765501 | <0.001 | 0.73649538866932 | 1.466814159292035 | 1.564159292035398
122 | IPI00115680 | Prkcsh | PRKCSH | O08795-1, | splice isoform 1 of glucosidase ii beta subunit precursor. | 1 | 1.93961753129663 | 0.028 | 2 | 1.02167459771155 | 0.874334084 | 3.476174211557 | 0.6996517107150175 | 0.6356791641057161 | yes
123 | IPI00403650 | Prss2 | PRSS2 | P07146, | [NAME] precursor. | 22 | 4.99154377285544 | <0.001 |  |  |  | 0.1111828916258 | 0.280132224346742 | 0.2935043073949173
124 | IPI00131845 | Psma6 | PSMA6 | Q9QUM9, | proteasome subunit alpha type 6. | 21 | 2.42281830798179 | 0.011057072 |  |  |  | 1.5775 | 1.276014527080372 | 0.8774869729985788 | yes
125 | IPI00131406 | Psma7 | PSMA7 | [NAME], | proteasome subunit alpha type 7. | 17 | 2.79125268085691 | 0.005577706 |  |  |  | 1.764479652882782 | 1.706126687435099 | 1.203011422637591 | yes
126 | IPI00462789 | Psmc5 | PSMC5 | Q8K1K2, | psmc5 protein. | 1 | 1.84875229972223 | 0.032 |  |  |  | 1.443116451489199 | 0.8000623290280134 | 0.8483673257384259 | yes
127 | IPI00654099 | Psmd9 | PSMD9 | [NAME], | blastocyst blastocyst cdna, riken full-length enriched library,clone:i1c0004n19 product:proteasome (prosome, macropain) 26s subunit,non-atpase, 9, full insert sequence. | 1 | 1.629386816257 | 0.049 | 1 | 1.00423290545447 | 0.407 | 0.176639344262295 | 1.064128075253256 | 1.073964363241679 | yes
128 | IPI00114671 | Ptprg | PTPRG | Q05909, | receptor-type tyrosine-protein phosphatase gamma precursor. | 1 | cancer only |  |  |  |  | 3.822381587725151 | 2.799791449426486 | 2.354014598540146
129 | IPI00223231 | Qscn6 | QSCN6 | Q3TE19,Q8BND5, | 12 days embryo spinal ganglion cdna, riken full-length enrichedlibrary, clone:d130065l08 product:quiescin q6, full insert sequence. | 85 | 1.94627542260101 | <0.001 | 66 | 0.792147531114685 | <0.001 | 0.26516464471438 | 1.662263192276983 | 1.17953836103651
130 | IPI00117239 | Reg1 | REG1A | P43137, | lithostathine 1 precursor. | 1 | 2.25729797654509 | 0.017 | 2 | 3.92814835097778 | <0.001 | 0.437943918196 | 0.3224199352002992 | 0.2536363066409618
131 | IPI00124288 | Reg2 |  | Q08731, | lithostathine 2 precursor. | 1 | cancer only |  |  |  |  | 0.3977932434347
132 | IPI00116548 | Reg3a |  | P35230, | regenerating islet-derived protein 3 beta precursor. | 2 | 1.41961560174582 | 0.844041739 | 1 | 2.40513688461261 | 0.016 | 0.144835269775585
133 | IPI00113806 | Reg3g | REG3 | O09049, | regenerating islet-derived protein 3 gamma precursor. | 17 | 5.91559054978609 | <0.001 | 6 | 2.76670826407445 | <0.001 | 0.681244768518
134 | IPI00125082 | Rnase4 | RNASE4 | P21570, | angiogenin-1 precursor. | 266 | 2.51771435734299 | <0.001 | 100 | 1.33934824548636 | <0.001 | 0.12492197281345 | 1.219849971148298 | 1.435747259088286
135 | IPI00313296 | Rnh1 | RNH1 | Q91VI7, | ribonuclease inhibitor. | 1 | 2.34571009473462 | 0.016 |  |  |  | 0.53152581353183 |  |  | yes
136 | IPI00128076 | Serpina3c |  | P29621, | serine protease inhibitor a3c precursor. |  |  |  | 1 | cancer only |  | 0.88327526132442
137 | IPI00136642 | Serpinc1 | SERPINC1 | P32261, | antithrombin-iii precursor. | 366 | 0.707271140882442 | <0.001 | 348 | 1.50637705221797 | <0.001 | 0.4844895194891 | 1.464939024390244 | 1.133765243902439 | yes | coagulation
138 | IPI00608017 | Shmt1 | SHMT1 | Q8R0X9,Q9CWR5, | [NAME] transferase 1. | 1 | cancer only |  |  |  |  | 0.421875 | 1.049883990719257 | 1.240429234338747 | yes
139 | IPI00131091 | C4b | C4B | P01029, | complement c4 precursor. | 87 | 1.9715972598153 | <0.001 | 123 | 1.80861904894832 | <0.001 | 1.52 | 1.32 | 1.02 | yes
140 | IPI00125333 | Slpi | SLPI | P97430, | antileukoproteinase 1 precursor. | 6 | 1.91009684598826 | 0.302158817 | 1 | 2.30096562302818 | 0.016 | 1.865399763686491 | 3.884087840238789 | 1.479248098926871
141 | IPI00114319 | Sod3 | SOD3 | O09164, | extracellular superoxide dismutase [cu-zn] precursor. | 27 | 2.93126188840535 | <0.001 | 12 | 0.254306926303957 | <0.001 | 4.744245524296675 | 0.4676859443090332 | 0.6106063963365094
142 | IPI00308484 | Sparcl1 | SPARCL1 | P70663, | sparc-like protein 1 precursor. | 38 | 1.64639539885422 | 0.021542334 | 19 | 0.842260666854395 | 0.001049417 | 5.744449358698 | 1.036986799880901 | 1.900122407119463
143 | IPI00120559 | Svs7 |  | Q09098, | seminal vesicle protein 7 precursor. | 8 | 3.52409453424583 | 0.030639027 | 1 | 4.04882594387915 | 0.004 | 1.394736842153
144 | IPI00120271 | Sycn | SYCN | Q8VCK7, | syncollin. | 15 | 4.23075632486232 | <0.001 | 1 | 4.97783178726963 | 0.004 | 0.119862794176
145 | IPI00222972 | Tbca | TBCA | P48428, | tubulin-specific chaperone a. | 1 | cancer only |  |  |  |  | 2.275245294353 | 1.178037279893907 | 1.248968540484786 | yes
146 | [NAME] | Tcrb-V20 |  | Q3V2G3,Q4G0C2,Q62352,Q792Y8,Q792Z0, | adult male small intestine cdna, riken full-length enriched library,clone:2010010o17 product:trypsinogen 16 homolog. | 1 | 5.38673187952198 | 0.004
147 | IPI00331352 | Tff2 | TFF2 | Q80YV5,Q9QX97, | trefoil factor 2/spasmolytic polypeptide protein. |  |  |  | 1 | 3.25751534814957 | 0.007 | 0.12713531556271 | 4.021469414176287 | 4.609396914446003
148 | IPI00122528 | [NAME] | TGFBI | P82198, | transforming growth factor-beta-induced protein ig-h3 precursor. |  |  |  | 1 | 2.38812193332684 | 0.016 | 15.89994437257 | 3.236013725197673 | 4.660618379829927
149 | IPI00118413 | Thbs1 | THBS1 | P35441, | thrombospondin 1. | 3 | 1.20446879092358 | 0.825922344 | 1 | 3.13178258825031 | 0.008 | 2.5671542553192 | 2.451637015996412 | 5.935715353565556
150 | IPI00114403 | Timp1 | TIMP1 | P12032, | tissue inhibitor of metalloproteinase 1. | 1 | cancer only |  |  |  |  | 21.984891676169 | 4.052892254988959 | 3.41195286542708
151 | IPI00137409 | Tkt | TKT | P40142, | transketolase. | 1 | cancer only |  |  |  |  | 3.355551845855 | 0.644699254086653 | 0.4612462307570227 | yes
152 | IPI00403938 | Tnc | TNC | Q80YX1,Q9WUU4, | [NAME] | 1 | cancer only |  |  |  |  | 179.9557614213 | 6.647450110864745 | 6.868070953436807
153 | IPI00317228 | Tnfrsf1a | TNFRSF1A | P25118, | tumor necrosis factor receptor superfamily member 1a precursor. | 2 | 2.5 | 0.048 |  |  |  | 1.4624927355739 | 2.383027774728291 | 2.605884290262378
154 | IPI00139788 | [NAME] | TF | Q921I1, | serotransferrin precursor. | 92 | 4.64717818528203 | <0.001 | 16 | 0.334102355595205 | <0.001 | 141.52677279354 | 0.422822061976223 | 0.3386766712141883 | yes | acute-phase, coagulation
155 | IPI00128108 | Try4 |  | Q62355,Q9R0T7, | pancreatic trypsin. | 60 | 2.65817175765797 | <0.001
156 | IPI00130391 | Trygn16 |  | Q9Z1R9, | trypsinogen 16. | 21 | 7.59265680922887 | <0.001 | 1 | cancer only
157 | IPI00466217 | Vasp | VASP | P70460, | vasodilator-stimulated phosphoprotein. | 1 | 2.26661075342962 | 0.017 |  |  |  | 4.179195665368 | 3.812447434819175 | 2.049516400336417
158 | IPI00649905 | Vcp | VCP |  | 89 kda protein. | 1 | cancer only |  | 7 | 0.776230453950025 | 0.018600059 | 1.659358398974171 | 1.176535694521306 | 0.9286109573879358 | yes
159 | IPI00119051 | Wfdc2 | WFDC2 | Q9DAU7, | wap four-disulfide core domain protein 2 precursor (HE-4) | 10 | 2.6333 | <0.001 |  |  |  | 24.987945238926 | 2.059456790123457 | 0.888567901234568
160 | [NAME] | [NAME] | XLKD1 | [NAME], | extra cellular link domain-containing 1. | 1 | cancer only |  |  |  |  | 1.974641675854465 | 1 | 1.965
161 | IPI00311064 | [NAME] | [NAME] | Q5Y5T1-1, | splice isoform 1 of probable palmitoyltransferase [NAME]. | 1 | cancer only |  |  |  |  | 3.4271519255456
162 | IPI00469007 | [NAME] | ZPBP2 | Q6X786-3, | splice isoform 3 of zona pellucida-binding protein 2 precursor. |  |  |  | 1 | cancer only |  | 0.5219519673348
163 | IPI00461863 |  |  |  | predicted: similar to bridging integrator 2 (predicted). | 1 | 2.79696206886562 | 0.01 | 1 | 0.981929219504333 | 0.437
164 | IPI00623553 |  |  |  | 19 kda protein hypotetical protein | 1 | cancer only
165 | IPI00649162 |  |  |  | similar to major urinary protein 1. | 1 | cancer only |  | 208 | 0.833897392627211 | <0.001
*Logsdon et al. [NAME]. 63, 2649 (2003).
#[NAME] et al., Cell 125 (1), 187 (2006); [NAME], Cell 125 (1), 173 (2006).
& Annotation according Ingenuity Pathway Analysis