Spreadsheet: 8faa7e93-af32-4965-a89c-1428631bcc0a
Sheet: Insulin_Signaling

HGNC.symbol | Ensembl.Gene.ID | [NAME] | Locus | GeneID | Col.Mean | Tra.Mean | Mat.Mean | traVcol.FC | [NAME] | matVtra.FC | matVtra.padj
ACACB | ENSG00000076555 | 32 | chr12:109577201-109706030 | ACACB | 0.75935 | 9.597675 | 7.77985833333333 | 15.0858628034592 | 4.41761943759178e-05 | 0.949876604892184 | 1
AKT1 | ENSG00000142208 | 207 | chr14:105235686-105262080 | AKT1 | 6.57994 | 27.308 | 12.3314116666667 | 4.6839216311548 | 0.000867370521094418 | 0.498921211050874 | 0.0222135033505696
ARAF | ENSG00000078061 | 369 | chr:X47420515-47431320 | ARAF | 3.737095 | 3.2479 | 2.92790166666667 | 0.923536287093079 | 0.886499915603233 | 1.29710689058557 | 0.536703917215308
BAD | ENSG00000002330 | 572 | chr11:64037299-64052176 | BAD | 1.751855 | 3.8188125 | 4.49025166666667 | 3.97333591924861 | 0.000116100237710965 | 1.30171391686383 | 0.650322781812918
CALM2 | ENSG00000143933 | 808 | chr2:47387220-47403740 | CALM2 | 15.55835 | 15.158325 | 14.4393666666667 | 0.910014479271098 | 0.86703437026676 | 1.33995500257411 | 0.425884734764442
CBLB | ENSG00000114423 | 868 | chr3:105377108-105587887 | CBLB | 0.7668355 | 0.79576575 | 0.400876166666667 | 0.49632405541838 | 0.00281700801644155 | 0.773726140544028 | 0.625313518555173
CRK | ENSG00000167193 | 1398 | chr17:1325457-1359544 | CRK | 1.560755 | 3.2808975 | 2.07195333333333 | 1.87710198119321 | 0.0206323638345996 | 0.928224545366716 | 1
EIF4E2 | ENSG00000135930 | 9470 | chr2:233415356-233433920 | EIF4E2 | 2.203985 | 3.6435125 | 2.06202 | 1.41592197930738 | 0.249253414278642 | 0.812174689479777 | 0.631751628112052
EIF4EBP1 | ENSG00000187840 | 1978 | chr8:37888019-37917883 | EIF4EBP1 | 4.79633 | 16.9596 | 7.34762333333333 | 3.88398027747305 | 1.22372803898258e-07 | 0.50738487553189 | 0.00153235987236557
ELK1 | ENSG00000126767 | 2002 | chr:X47494919-47510003 | ELK1 | 1.62692 | 3.9361625 | 2.22045833333333 | 2.47924329956246 | 0.00183854813124984 | 0.698004130081052 | 0.216608831730884
EXOC7 | ENSG00000182473 | 23265 | chr17:74077085-74099868 | EXOC7 | 1.657315 | 1.4242075 | 1.62227166666667 | 1.07052914377153 | 0.953923002139701 | 1.01555059712061 | 1
FASN | ENSG00000169710 | 2194 | chr17:80036213-80056106 | FASN | 28.348375 | 372.627 | 562.086166666667 | 18.9185214556129 | 0.000100092526093573 | 1.6476446146819 | 0.0593354652767123
[NAME] | ENSG00000165140 | 2203 | chr9:97365420-97402531 | [NAME] | 5.792485 | 13.027025 | 7.58147333333333 | 2.50366387053428 | 0.000332798988281762 | 0.740584400130552 | 0.394830203321571
FLOT2 | ENSG00000132589 | 2319 | chr17:27206356-27224715 | FLOT2 | 2.900745 | 2.910525 | 4.876755 | 0.967785818815897 | 0.964088609874906 | 2.08368143956061 | 0.000890965785378893
FOS | ENSG00000170345 | 2353 | chr14:75745480-75748937 | FOS | 9.322215 | 3.24620225 | 2.01400106666667 | 0.319213473423603 | 0.188751190628133 | 0.829750352900314 | 1
FOXO1 | ENSG00000150907 | 2308 | chr13:41129800-41240734 | FOXO1 | 0.643354 | 0.254805 | 0.313287833333333 | 0.526690138695636 | 0.0116788978178216 | 1.62406104110522 | 0.0678475450246375
G6PC | ENSG00000131482 | 2538 | chr17:41052814-41065386 | G6PC | 0 | 0 | 0 | Inf | 1 | 0 | 1
GRB2 | ENSG00000177885 | 2885 | chr17:73314156-73401790 | GRB2 | 26.8997 | 7.2920025 | 5.16919333333333 | 0.269838831173889 | 4.71712294180464e-09 | 0.912919676438697 | 0.969019633304017
GSK3B | ENSG00000082701 | 2932 | chr3:119540801-119813264 | GSK3B | 1.82171 | 2.513035 | 1.59982 | 1.24189895297651 | 0.612757917043812 | 0.87115668544436 | 0.944334424184291
[NAME] | ENSG00000104812 | 2997 | chr19:49471381-49496610 | [NAME] | 1.0688045 | 3.1546575 | 2.09180333333333 | 2.9438056279503 | 5.58325995879291e-05 | 0.839729358175331 | 0.789717243245573
HK1 | ENSG00000156515 | 3098 | chr10:71029755-71161637 | HK1 | 4.26847 | 2.3543075 | 2.77863666666667 | 0.648346647696274 | 0.100922581625495 | 1.31714836299259 | 0.45467005924016
HRAS | ENSG00000174775 | 3265 | chr11:532241-535550 | HRAS | 1.06674 | 1.6017825 | 1.81055666666667 | 1.95408580848808 | 0.0231679651154754 | 1.09107417443894 | 1
[NAME] | ENSG00000197081 | 3482 | chr6:160390130-160527583 | [NAME] | 8.796225 | 2.1021825 | 1.770375 | 0.265284404563585 | 6.32052506160531e-10 | 0.981593932890322 | 1
IGFBP1 | ENSG00000146678 | 3484 | chr7:45927958-45933267 | IGFBP1 | 0 | 0 | 0 | NA | NA | NA | NA
IGFBP2 | ENSG00000115457 | 3485 | chr2:217498126-217529158 | IGFBP2 | 0.1800261 | 3.659255 | 15.9963333333333 | 22.1688711821978 | 2.61084742068483e-13 | 5.34369944924082 | 2.07518392591997e-07
IKBKB | ENSG00000104365 | 3551 | chr8:42128819-42190171 | IKBKB | 1.21862 | 0.56549725 | 0.328719333333333 | 0.405785846275392 | 0.00015338110868821 | 0.603337360531929 | 0.0550637407515733
INPP5K | ENSG00000132376 | 51763 | chr17:1397870-1420182 | INPP5K | 0.882159 | 2.153705 | 2.26667833333333 | 2.31381502044904 | 0.00161665967930158 | 1.28683021426254 | 0.534449712126738
INPPL1 | ENSG00000165458 | 3636 | chr11:71935881-71950188 | INPPL1 | 3.594085 | 3.994575 | 3.23564333333333 | 1.28224460454918 | 0.783408746975745 | 0.936180075182218 | 1
INS | ENSG00000254647 | 3630 | chr11:2181008-2182439 | INS | 0 | 0 | 0 | NA | NA | NA | NA
INSR | ENSG00000171105 | 3643 | chr19:7112265-7294011 | INSR | 0.366365 | 0.99753425 | 0.949591166666667 | 3.54509271667659 | 0.002620136924177 | 1.20308125023408 | 0.740844272722778
IRS2 | ENSG00000185950 | 8660 | chr13:110406183-110438914 | IRS2 | 1.096915 | 2.7766425 | 1.83283333333333 | 2.72422905901486 | 0.00518029652279101 | 0.863719730346656 | 0.950077646227517
JUN | ENSG00000177606 | 3725 | chr1:59246462-59249785 | JUN | 10.481395 | 5.70870875 | 3.23754316666667 | 0.537440304528038 | 0.19261299627063 | 0.762525965033308 | 0.946599201227889
LIPE | ENSG00000079435 | 3991 | chr19:42905665-42931578 | LIPE | 0.03971085 | 0.7367455 | 0.967535666666667 | 10.2345451228413 | 0.000374756242353812 | 1.55623094726456 | 0.265547853887028
MAP2K2 | ENSG00000126934 | 5605 | chr19:4090319-4124126 | MAP2K2 | 5.679175 | 13.9591 | 8.80106333333333 | 3.093589605993 | 9.20910547481633e-06 | 0.773209893830046 | 0.464571330721154
MAP3K13 | ENSG00000073803 | 9175 | chr3:185000728-185206882 | MAP3K13 | 1.91398 | 6.8754325 | 7.40077833333333 | 3.28122913207603 | 6.9641153104615e-06 | 1.53421725605027 | 0.130680862282781
MAPK3 | ENSG00000102882 | 5595 | chr16:30125425-30134630 | MAPK3 | 1.25157 | 2.467195 | 2.77434333333333 | 2.18218244161632 | 0.00466824446376501 | 1.39411509613848 | 0.338944177170698
MAPK9 | ENSG00000050748 | 5601 | chr5:179660594-179719071 | MAPK9 | 0.834361 | 1.547485 | 1.95705833333333 | 2.0512834983738 | 0.00626936011539925 | 1.64914161661382 | 0.0525577164616396
MKNK2 | ENSG00000099875 | 2872 | chr19:2037469-2051243 | MKNK2 | 3.841015 | 11.637665 | 12.23681 | 3.75631496353948 | 0.000532731383984074 | 1.22740734618968 | 0.82733133351144
MTOR | ENSG00000198793 | 2475 | chr1:11166587-11322608 | MTOR | 0.7866455 | 1.75422 | 1.1317055 | 2.44515056240624 | 0.0609140491669819 | 0.830405469869601 | 0.994921833220408
PCK2 | ENSG00000100889 | 5106 | chr14:24563482-24573339 | PCK2 | 3.73785 | 1.36591 | 1.25310833333333 | NA | NA | NA | NA
PDE3B | ENSG00000152270 | 5140 | chr11:14665268-14893604 | PDE3B | 0.296738 | 0.01003475 | 0.00334216333333333 | 0.0434731850060174 | 4.97595555472372e-31 | 0.277341373680631 | 0.19090318629951
PDPK1 | ENSG00000140992 | 5170 | chr16:2587969-2653189 | PDPK1 | 1.38063 | 1.2490115 | 0.970397166666667 | 0.865837019461249 | 0.732891211056643 | 0.897581501327513 | 0.975606427148949
PIK3R2 | ENSG00000105647 | 5296 | chr19:18264015-18281343 | PIK3R2 | 1.790455 | 3.70048 | 2.83933666666667 | 2.89552661055097 | 4.55977955579946e-05 | 0.876329034593697 | 0.929819656381369
PKM2 | ENSG00000067225 | 5315 | chr15:72491369-72523727 | PKM2 | 51.12665 | 8.0259675 | 6.405375 | 0.167080069825452 | 1.84684323323677e-16 | 1.01681371396134 | 1
PPARGC1A | ENSG00000109819 | 10891 | chr4:23793643-23891700 | PPARGC1A | 0.01137845 | 0 | 0.00164779833333333 | 0.0624605502578007 | 0.00450686262524147 | 0.423712272241361 | 0.886703327162716
PPP1CB | [NAME] | 5500 | chr2:28974613-29025806 | PPP1CB | 5.903865 | 14.1826 | 9.62007666666667 | 2.44701199273423 | 0.000478845655432781 | 0.840162059246658 | 0.759795303121952
PRKAG1 | ENSG00000181929 | 5571 | chr12:49396054-49412629 | PRKAG1 | 2.476395 | 4.3769 | 2.21369666666667 | NA | NA | NA | NA
PRKAR1A | ENSG00000108946 | 5573 | chr17:66508109-66528910 | PRKAR1A | 6.550535 | 8.53217 | 7.34917 | 1.33398295363432 | 0.362552232616528 | 1.11934747991804 | 0.9419958788209
PRKCZ | ENSG00000067606 | 5590 | chr1:1981908-2116834 | PRKCZ | 0.4968315 | 3.419735 | 2.503865 | 9.30558204050121 | 6.1478160069182e-15 | 0.82534686657004 | 0.750742209785234
PTPN1 | ENSG00000196396 | 5770 | chr20:49126890-49201086 | PTPN1 | 5.44784 | 2.08329 | 1.12347566666667 | 0.371032180196745 | 1.60983889189617e-05 | 0.695474938288711 | 0.235900668159186
PTPRF | ENSG00000142949 | 5792 | chr1:43996546-44089343 | PTPRF | 0.4059785 | 3.5709675 | 8.28042666666667 | 11.2902331981761 | 1.49503148923189e-17 | 2.74076723178297 | 2.36529120244904e-06
PYGB | ENSG00000100994 | 5834 | chr20:25228705-25278648 | PYGB | 2.31984 | 4.0954475 | 4.07027666666667 | 1.79637825776618 | 0.0415803776232935 | 1.18629243368533 | 0.667396843207823
RAPGEF1 | ENSG00000107263 | 2889 | chr9:134452156-134612925 | RAPGEF1 | 6.307925 | 1.09356725 | 1.09386816666667 | 0.194075094224325 | 4.9998105204688e-14 | 1.17593963885625 | 0.830671107024529
RHEB | ENSG00000106615 | 6009 | chr7:151163097-151217010 | RHEB | 3.626705 | 2.543665 | 2.60406333333333 | 0.73489902831849 | 0.314095946735792 | 1.2022800051272 | 0.78891925969652
RHOQ | ENSG00000119729 | 23433 | chr2:46769866-46811827 | RHOQ | 3.925645 | 1.114857 | 0.522478833333333 | 0.170279442632466 | 3.11518246966994e-13 | 0.597532136934556 | 0.123627729585539
RPS6 | ENSG00000137154 | 6194 | chr9:19376253-19380235 | RPS6 | 69.48975 | 239.7575 | 89.2833666666667 | 3.68996308057202 | 1.79973966539889e-07 | 0.475388694909739 | 0.000279980378664006
RPS6KB2 | ENSG00000175634 | 6199 | chr11:67195934-67202879 | RPS6KB2 | 1.960725 | 3.2411625 | 2.40936666666667 | 1.91538565326763 | 0.0414404542250665 | 0.856951561309152 | 0.878586151283497
RPTOR | ENSG00000141564 | 57521 | chr17:78518624-78940173 | RPTOR | 0.960449 | 1.5138725 | 1.0929505 | 1.52835653407749 | 0.177205430243251 | 0.913152974732233 | 1
SH2B2 | ENSG00000160999 | 10603 | chr7:101928404-101962178 | SH2B2 | 0.7640115 | 0.250052575 | 0.308876033333333 | 0.206976174534012 | 5.06396779661823e-06 | 1.43046640086794 | 0.79663129847023
SHC1 | ENSG00000160691 | 6464 | chr1:154934773-154946959 | SHC1 | 2.98737 | 4.1806075 | 2.55130333333333 | 1.61190070624837 | 0.0981235286075608 | 0.712845729999684 | 0.26092632867203
SLC2A1 | ENSG00000117394 | 6513 | chr1:43391045-43424847 | SLC2A1 | 3.02036 | 2.6097275 | 4.125905 | 0.911227592971785 | 0.885312467754842 | 2.03674254010116 | 0.047434103370228
SLC2A4 | ENSG00000181856 | 6517 | chr17:7185053-7191367 | SLC2A4 | 0.1197026 | 0.26334575 | 0.0587139666666667 | 5.5741987374014 | 0.000200696455892054 | 0.286870044040648 | 0.00731376441926111
SLC2A9 | ENSG00000109667 | 56606 | chr4:9827847-10041872 | SLC2A9 | 1.90449 | 3.9522525 | 5.72257833333333 | 2.88210731492841 | 0.00596120099956906 | 1.44667355989886 | 0.170100351740202
SOCS3 | ENSG00000184557 | 9021 | chr17:76352858-76356158 | SOCS3 | 4.955435 | 0.212302325 | 0.0312967333333333 | 0.0424279208949018 | 6.40213811312347e-07 | 0.22849136606737 | 0.0454955298610864
SORBS1 | ENSG00000095637 | 10580 | chr10:97071529-97321171 | SORBS1 | 0.0466497 | 0.14602195 | 0.128053366666667 | 6.76889241702519 | 0.370520101972757 | 1.00827871963038 | 1
SOS2 | ENSG00000100485 | 6655 | chr14:50583845-50698099 | SOS2 | 0.758949 | 0.7594745 | 0.624179 | 0.82118826398081 | 0.579130588505878 | 1.21048050940009 | 0.704445289436103
SREBF1 | ENSG00000072310 | 6720 | chr17:17714662-17740325 | SREBF1 | 5.782415 | 22.52755 | 16.4694166666667 | 4.28537126861485 | 0.000281687045220069 | 0.869839499797644 | 0.910239019897001
TRIB3 | ENSG00000101255 | 57761 | chr20:361307-378203 | TRIB3 | 0.7014275 | 2.55966 | 2.31930333333333 | 3.98851904819415 | 0.360468284889787 | 1.05764785316588 | 1
TRIP10 | ENSG00000125733 | 9322 | chr19:6739706-6751529 | TRIP10 | 1.488065 | 0.3856005 | 0.8217565 | 0.319695010011367 | 1.29694675690278e-06 | 2.03273166659713 | 0.0032935381844572
[NAME] | ENSG00000165699 | 7248 | chr9:135766734-135820020 | [NAME] | 0.473841 | 0.21748425 | 0.179169 | 0.402911005279588 | 0.000114338277771098 | 0.947668847774034 | 1
TSC2 | ENSG00000103197 | 7249 | chr16:2097989-2138713 | TSC2 | 1.22278 | 3.56485 | 3.382295 | 3.01009450507925 | 0.00402210419889512 | 1.08669076554134 | 0.945000950376404