Spreadsheet: f8860159-b06b-4282-be8f-29fc3775b8c8
Sheet: Sheet1

Test Referenced | Entry Type | Mayo ID | Description | Reporting Description | Method | Collection Container | Temperature | Stability | [NAME] | Unit of Measure | [NAME] | Minimum Volume | Reject Due To | Reference Values | Days/Times Performed | Analytic Time | Maximum Lab Time | CPT Units | CPT Code | LOINC® Code | LOINC® Attributes | Always Performed | Orderable Separately | Performing Location
BTKMP | Test | BTKMP | Bruton's [NAME] (BTK) Genotype and Protein Analysis, Known Mutation Sequencing and Flow Cytometry | BTK Known Mutation Panel, B | BTKKM/29304, BTKKQ/89286: Polymerase Chain Reaction (PCR) followed by DNA Sequence Analysis (PCR is utilized pursuant to a license agreement with Roche Molecular Systems, Inc.) BTK/89011: Flow Cytometry |  |  |  |  |  | Forms:  1. Bruton's [NAME] (BTK) Genotype Patient Information Sheet (Supply T620) in Special Instructions 2. New York Clients-Informed consent is required. Please document on the request form or electronic order that a copy is on file. An Informed Consent for Genetic Testing (Supply T576) is available in Special Instructions.   Ordering physician name and phone number are required.   For serial monitoring, we recommend that specimen draws be performed at the same time of day.   Specimens must arrive within 72 hours of draw. Send specimens Sunday through Thursday only. Draw and package specimens as close to shipping time as possible. Ship specimens overnight.   Two separate EDTA specimens are required.   Specimen Type: Blood for BTKKM/29304 Bruton's [NAME] (BTK) Genotype, Known Mutation and [NAME] [NAME] (BTK) Genotype, Known Mutation Sequencing Container/Tube: Lavender top (EDTA) [NAME]: 3 mL Collection Instructions: 1. Send specimen in original tube. 2. Label as BTKKM/29304 and [NAME]. Additional Information: Transfusions will interfere with testing for up to 4 to 6 weeks. DNA obtained from white cells may not provide useful information for patients who received a recent transfusion of blood that was not leukocyte-reduced. Wait 4 to 6 weeks until transfused cells have left the patient's circulation before drawing the patient's blood specimen for genotype testing.  	 [NAME] for BTK/89011 Bruton's [NAME] (Btk), [NAME], Flow Cytometry, Blood Container/Tube: Lavender top (EDTA) [NAME]: 5 mL Collection Instructions: 1. Send specimen in original tube. Do not aliquot. 2. Label as BTK/89011. | BTKKM/29304 Bruton's [NAME] | Hemolysis	Mild OK; Gross reject Thawing	BTKKM,BTKKQ: Warm OK; Cold OK BTK: Warm reject; Cold reject Lipemia	Mild OK; Gross reject Icterus	NA Other	NA | An interpretive report will be provided. | Varies | 4 weeks | 6 weeks |  | Profile |  |  |  |  | Rochester
BTKMP | [NAME] | WBEDTA | [NAME] EDTA |  |  |  | Refrigerated | 72 hours
BTKMP | Component | BTKKM | Bruton's [NAME] (BTK) Genotype, Known Mutation Sequence | BTK Gene, Known Mutation | Polymerase Chain Reaction (PCR) Followed by DNA Sequence Analysis (PCR is utilized pursuant to a license agreement with Roche Molecular Systmes, Inc.) Only orderable as part of a profile. For further information see #89306 "Bruton's Tyrosine Kinase (BTK) Genotype, Known Mutation Sequence". |  |  |  |  |  | "Bruton's Tyrosine Kinase (BTK) Genotype Patient Information Sheet" (Supply T620) must be submitted with the specimen. See Special Instructions for a copy of the form.   Draw blood in a lavender-top (EDTA) tube(s), and send 3.0 mL  of EDTA whole blood in original VACUTAINER(S). Note: 	1.	  Include physician's name and phone number with  		  the specimen. 2.     Bone marrow transplants will interfere with testing.  		For bone marrow transplant patients, buccal cells  		should be provided from the recipient to obtain an  		accurate genotype. 3.     Transfusions will interfere with testing for up to 4 to 6 		weeks. DNA obtained from white cells may not 		provide useful information for patients who received a 		recent transfusion of blood that was not 		leukocyte-reduced. Wait 4 to 6 weeks until transfused 		cells have left the patient's circulation before drawing 		the patient's blood specimen for genotype testing. 4.    An "Informed Consent for DNA Testing" (Supply T576)  		is available. See Special Instructions for a copy of the form. 		  Only orderable as part of a profile. For further information see #89306 "Bruton's Tyrosine Kinase (BTK) Genotype, Known Mutation Sequence." | 0.3 mL |  | Only orderable as part of a profile. For further information see #89306 "Bruton's Tyrosine Kinase (BTK) Genotype, Known Mutation Sequence." |  |  |  | 1 | 81479 |  |  | Yes | Yes (order BTKK)
BTKKM | [NAME] | WBEDTA | [NAME] EDTA |  |  |  | Refrigerated
BTKKM | Result | 29304 | BTK Known Mut Result | BTK Known Mut Result | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 69479-4
BTKKM | Result | 45477 | BTK Known Mut Interpretation | BTK Known Mut Interpretation | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 69047-9 | Service comment 01:Imp:Pt:[NAME]:Nom:
BTKKM | Result | 45478 | Reviewed By | Reviewed By | Numeric
BTKMP | Component | BTKKQ | Bruton's [NAME] (BTK) Genotype, Known Mutation Sequencing | BTK Gene, Known Mutation Sequencing | Only orderable as part of a profile. For further information see BTKK/89306 Bruton's [NAME] (BTK) Genotype, Known Mutation. |  |  |  |  |  | Only orderable as part of a profile. For further information see BTKK/89306 Bruton's [NAME] (BTK) Genotype, Known Mutation. |  |  | Only orderable as part of a profile. For further information see BTKK/89306 Bruton's [NAME] (BTK) Genotype, Known Mutation. |  |  |  | 1 |  |  |  | Yes | No
BTKKQ | [NAME] | WBEDTA | [NAME] EDTA |  |  |  | Refrigerated
BTKKQ | Result | BTKKQ | BTK Gene, Known Mutation Sequencing | BTK Gene, Known Mutation Sequencing | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | In Process
BTKMP | Component | BTK | Bruton [NAME] (Btk), [NAME], Flow Cytometry, Blood | Btk Protein Flow, B | Flow Cytometry |  |  |  | 5 | mL | [NAME] must arrive within 72 hours of draw. Send specimen Sunday through Thursday only. Collect and package specimen as close to shipping time as possible. Ship specimen overnight.   Container/Tube: Lavender top (EDTA) [NAME]: 5 mL Collection Instructions: Send specimen in original tube. Do not aliquot. Additional Information: 1. Ordering physician name and phone number are required. 2. For serial monitoring, we recommend that specimen draws be performed at the same time of day. | 2 mL | Hemolysis	Mild OK; Gross reject Thawing	NA Lipemia	Mild OK; Gross reject Icterus	NA Other	NA | Present [NAME] expression will be reported as present, absent, partial deficiency, or [NAME] (carrier). | Monday through Friday Do not send specimen after Thursday. Specimen must be rece | 3 days | 4 days | 1 | 88184 |  |  | Yes | Yes
BTK | [NAME] | WBEDTA | [NAME] EDTA |  |  |  | Refrigerated | 72 hours
BTK | Result | 89011 | Btk Protein Flow, B | Btk Protein Flow, B | Alphanumeric |  |  |  |  |  |  |  |  |  |  |  |  |  |  | In Process