Spreadsheet: 301294e8-bbd1-4312-8c50-4382924d83bb
Sheet: Chemical Data

Item Name | Plate Location | CAS Number | Concentration | Catalog Number | Target | Description
ABT-263 (Navitoclax) | a1-L1700-01 | 923564-51-6 | 10 mM | S1001 | Bcl-2 | ABT263, Navitoclax Bcl-2 Family Inhibitor. [NAME]'s of <1 nmol/L for Bcl-2, Bcl-xL, and [NAME]
ABT-737 | a2-L1700-01 | 852808-04-9 | 10 mM | S1002 | Bcl-2 | ABT-737 is a pan-Bcl-2 inhibitor. ABT737 single-agent LC90 values ranges from 100 nM for COG-LL-319.
Linifanib ([NAME]) | a3-L1700-01 | 796967-16-3, 1145655-58-8 (HCl), 796967-17-4 (TFA) | 10 mM | S1003 | PDGFR, VEGFR | ABT-869 (Linifanib) is a structurally novel, potent RTK and VEGF and PDGF receptor families inhibitor with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGFR-β, KDR, and CSF-1R, respectively.
ABT-888 (Veliparib) | a4-L1700-01 | 912444-00-9, 912445-05-7 (2HCl) | 10 mM | S1004 | PARP | ABT-888 is a potent inhibitor of both [NAME] and PARP-2 by [3H]NAD+ with Kis of 5.2 and 2.9 nmol/L, respectively.
Axitinib | a5-L1700-01 | 319460-85-0 | 10 mM | S1005 | VEGFR, PDGFR, c-Kit | Axitinib blocked phosphorylation of VEGFR-2 and VEGFR-3 with average IC50s of 0.2 and 0.1 to 0.3 nM.
Saracatinib (AZD0530) | a6-L1700-01 | 379231-04-6, 893428-72-3 (Fumaric acid), 893428-71-2 (3H2O) | 10 mM | S1006 | Src, Bcr-Abl | Saracatinib (AZD0530) is a Src inhibitor of c-Src with IC50 of 2.7 nM.
AZD6244 (Selumetinib) | a7-L1700-01 | 606143-52-6, 942275-12-9 (4-methylbenzenesulfonate) | 10 mM | S1008 | MEK | AZD6244 ([NAME]) is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm.
BEZ235 (NVP-BEZ235) | a8-L1700-01 | 915019-65-7, 1028385-32-1 (4-methylbenzenesulfonate) | 10 mM | S1009 | mTOR, PI3K | BEZ235 (NVP-BEZ235) is a dual ATP-competitive phosphatidylinositol 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor with an IC50 of 4, 5, 7 and 75 nM for p110α, [NAME], p110δ and [NAME], respectively.
BIBF1120 (Vargatef) | a9-L1700-01 | 656247-17-5, 790241-30-4 (methanesulfonate), 959761-73-0 (HCl) | 10 mM | S1010 | VEGFR, PDGFR, FGFR | BIBF1120 ([NAME]) is a potent VEGF receptor (VEGFR), PDGFR and FGFR kinase inhibitor to VEGFR1, VEGFR2,VEGFR3 with IC50 of 34, 13 and 13 nM, respectively.
Afatinib (BIBW2992) | a10-L1700-01 | 439081-18-2, 936631-70-8 (Maleic acid), 1254955-21-9 (XHCl) | 10 mM | S1011 | EGFR, [NAME] | BIBW2992 ([NAME]) is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.
Bortezomib (Velcade) | a11-L1700-01 | 179324-69-7 | 10 mM | S1013 | Proteasome | Bortezomib also known as Velcade, MG-341, PS-341 is proteasome Inhibitor, effectively inhibits proteasome activity (Ki-0.6 nM).
Bosutinib (SKI-606) | b1-L1700-01 | 380843-75-4, 918639-08-4 (H2O), 918639-09-5 (2-propanol) | 10 mM | S1014 | Src | Bosutinib (SKI-606) is a [NAME] family kinase inhibitor. It inhibited migration of breast cancer cell lines with IC50 values of 0.1 to 0.3 umol/L.
Cediranib (AZD2171) | b2-L1700-01 | 288383-20-0, 857036-77-2 (Maleic acid) | 10 mM | S1017 | VEGFR, Flt | Cediranib (AZD2171) inhibited VEGF-stimulated proliferation and KDR phosphorylation with IC50 of 0.4 and 0.5 nM, respectively.
CI-1033 (Canertinib) | b3-L1700-01 | 267243-28-7, 289499-45-2 (2HCl) | 10 mM | S1019 | EGFR, [NAME] | CI-1033 is an orally bioavailable irreversible Pan-erbB tyrosine kinase inhibitor, targeting EGFR with IC50 of 0.8, 19 and 7 nM for EGFR, HER-2 and ErbB-4, respectively.
CI-1040 (PD184352) | b4-L1700-01 | 212631-79-3 | 10 mM | S1020 | MEK | MEK 1/2 inhibitor. Ki of 300nM
[NAME] (BMS-354825) | [NAME] | 302962-49-8, 854001-07-3 (HCl) | 10 mM | S1021 | Src, Bcr-Abl, c-Kit | [NAME] also known as BMS-354825, Sprycel, BMS354825 is ATP-competitive, dual SRC/ABL inhibitor. BMS-354825 inhibits all members of the [NAME] family, including c-Src, Lck, [NAME], and Yes (IC50 < 1.1nmol/L).
[NAME] (Ridaforolimus) | b6-L1700-01 | 572924-54-0, 697252-87-2 | 10 mM | S1022 | mTOR | [NAME] (Ridaforolimus, AP23573 and MK-8669) is a small-molecule inhibitor of mTOR.
Erlotinib HCl | b7-L1700-01 | 183319-69-9, 183321-74-6 (free base), 248594-19-6 (methanesulfonate) | 10 mM | S1023 | EGFR | Erlotinib also known as Tarceva, CP-358774, OSI-774, NSC-718781 is a HCL salt with IC50 of 2 nM for HER1/EGFR TK.
Gefitinib (Iressa) | b8-L1700-01 | 184475-35-2, 184475-55-6 (HCl) | 10 mM | S1025 | EGFR | Gefitinib also known as ZD-1839 & Iressa is a novel potent EGFR tyrosine kinase & Akt phosphorylations inhibitor with IC50 of 37, 26 and 57 nM.
[NAME] | b9-L1700-01 | 220127-57-1, 152459-95-5 (free base), 862366-25-4 (HCL) | 10 mM | S1026 | PDGFR, c-Kit, Bcr-Abl | Imatinib also known as [NAME], Glivec, CGP-57148B, STI-571 and [NAME] is a multitargeted c-kit, [NAME]-R and c-ABL inhibitor with IC50 of 3.9 and 2.9 μM for the inhibition of T-cell proliferation stimulated by DCs and PHA.
[NAME] ([NAME]) | b10-L1700-01 | 388082-77-7, 231277-92-2 (free base), 1187538-35-7 (4-methylbenzenesulfonate) | 10 mM | S1028 | EGFR, [NAME] | EGFR and HER2 autophosphorylation inhibitor, against purified [NAME] and [NAME] of 10.2 and 9.8 nM, respectively.
Lenalidomide | b11-L1700-01 | 191732-72-6, 1243329-97-6 (HCl) | 10 mM | S1029 | TNF-alpha | Lenalidomide also known as CC-5013 and [NAME] is TNF-alpha inhibitor. Revlimid with purity >99% and solubility DMSO is available.
Panobinostat | c1-L1700-01 | 404950-80-7, 960055-57-6 (Maleic acid), 960055-60-1 (methanesulfonate) | 10 mM | S1030 | HDAC | LBH589 (Panobinostat) is a HDAC inhibitor, IC50 for inhibition of proliferation in MOLT-4 cells is approximately 5 μM and for [NAME] cells is approximately 20 μM.
Motesanib Diphosphate | c2-L1700-01 | 857876-30-3, 453562-69-1 (free base), 945716-97-2 (H2O) | 10 mM | S1032 | VEGFR, PDGFR, c-Kit | A multiple inhibitor of VEGFR1/2/3 (IC50: 2 ηM /3 ηM /6 ηM),PDGFR (84ηM), kit (8ηM), and Ret (59ηM)receptors
Nilotinib (AMN-107) | c3-L1700-01 | 641571-10-0 | 10 mM | S1033 | Bcr-Abl | Inhibitor of BCR-ABL, IC50 < 30nM
Pazopanib HCl | c4-L1700-01 | 635702-64-6, 444731-52-6 (free base) | 10 mM | S1035 | VEGFR, PDGFR, c-Kit | VEGFR inhibitor, IC50 of 10, 30, and 47 nM for VEGFR-1, -2, and -3.
PD0325901 | c5-L1700-01 | 391210-10-9, 870474-62-7 | 10 mM | S1036 | MEK | PD0325901 is selective and non ATP-competitive mitogen activated protein kinase kinase (MEK or MAPKK) MEK inhibitor with an IC50 of 0.33 nM for inhibiton of MEK activity in mouse colon 26 cells.
PI-103 | c6-L1700-01 | 371935-74-9, 371935-79-4 (HCl) | 10 mM | S1038 | DNA-PK, PI3K, mTOR | PI-103 is a potent, cell-permeable, ATP-competitive PI3K family members inhibitor with IC50 of 2, 8, 20, 26, 48, 83, 88, 150 nM for DNA-PK, p110α, mTORC1, PI3-KC2β, p110δ, mTORC2, [NAME], and [NAME], respectively.
Rapamycin (Sirolimus) | c7-L1700-01 | 53123-88-9, 1179372-35-0, 1189166-54-8, 1233221-34-5, 1353039-01-6 | 10 mM | S1039 | mTOR | Rapamycin also known as Sirolimus and Rapamune is a mTOR inhibitor. Rapamycin Sirolimus inhibits cell motility by suppression of mTOR-mediated pathways.
Sorafenib (Nexavar) | c8-L1700-01 | 475207-59-1, 284461-73-0 (free base) | 10 mM | S1040 | VEGFR, PDGFR, Raf | [NAME] is a novel, small molecular inhibitor of several tyrosine protein kinases (VEGFR and PDGFR) and RAF/MEK/ERK cascade inhibitor with an IC50 of 6, 22, 38 nM for Raf-1, wt [NAME] and V599E mutant [NAME].
Sunitinib Malate (Sutent) | c9-L1700-01 | 341031-54-7, 557795-19-4 (free base), 1126641-10-8 ( Maleic acid) | 10 mM | S1042 | VEGFR, PDGFR, c-Kit, Flt | Sunitinib Malate (Sutent) is a multitargeted FLT3, PDGFRs, VEGFRs, and [NAME] kinase inhibitor with [NAME] of 0.009 and 0.008 µM for Flk-1 and PDGFR.
Tandutinib (MLN518) | c10-L1700-01 | 387867-13-2, 1227636-16-9 (3H2O) | 10 mM | S1043 | Flt | Tandutinib (MLN518, CT53518) is an ATP-competitive and highly selective inhibitor of FLT3, PDGFR and c-Kit with IC50 of 0.22 μM, 0.20 μM and 0.17 μM, respectively.
Temsirolimus (Torisel) | c11-L1700-01 | 162635-04-3, 343261-52-9, 1034922-90-1 | 10 mM | S1044 | mTOR | mTOR inhibitor.
[NAME] (TSA) | d1-L1700-01 | 58880-19-6, 204577-24-2 (sodium salt) | 10 mM | S1045 | HDAC | Inhibitor of HDAC, HDAC inhibitory activity of TSA was similar in all cell lines with mean ± SD IC50 of 2.4 ± 0.5 nm (range, 1.5–2.9 nm) .
[NAME] (Zactima) | d2-L1700-01 | 443913-73-3, 338992-53-3 (TFA), 524722-52-9 (HCl) | 10 mM | S1046 | VEGFR | Vandetanib is a VEGFR and EGFR antagonist and a tyrosine kinase inhibitor with IC50 of 60, 90, 40 nM for HUVEC proliferation, PC-9 cells and tyrosine kinase activity, respectively.
Vorinostat (SAHA) | d3-L1700-01 | 149647-78-9 | 10 mM | S1047 | HDAC | Vorinostat also known as SAHA, [NAME], MK-0683 is an HDAC inhibitor. Vorinostat CAS No 149647-78-9 with purity >99% & solubility DMSO is available.
VX-680 (MK-0457, Tozasertib) | d4-L1700-01 | 639089-54-6, 639090-58-7 (sulfate) | 10 mM | S1048 | [NAME] | VX-680 is the inhibitor of Aurora-A,-B,-C kinases with apparent inhibition constant values of 0.6,18,4.6 nM respectively.
Entinostat (MS-275, SNDX-275) | d5-L1700-01 | 209783-80-2, 209784-79-2 (Maleic acid), 209784-80-5 (HCl) | 10 mM | S1053 | HDAC | MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8µM for HDAC1 and HDAC3, respectively.
Enzastaurin (LY317615) | d6-L1700-01 | 170364-57-5, 365253-37-8 (2HCl) | 10 mM | S1055 | PKC | Enzastaurin (LY317615) is a potent PKC beta inhibitor with an IC50 of 6 nM.
BMS-599626 ([NAME]) | d7-L1700-01 | 714971-09-2, 873837-23-1 (HCl), 873837-22-0 (H2O) | 10 mM | S1056 | EGFR, [NAME] | BMS-599626 is a highly selective pan-HERKinase inhibitor with IC50 of 20 and 30 nM for the inhibition of HER1and HER2, respectively.
Obatoclax mesylate (GX15-070) | d8-L1700-01 | 803712-79-0, 803712-67-6 (free base) | 10 mM | S1057 | Bcl-2 | Bcl-2 homology domain-3 ([NAME]) mimetic,antagonize all antiapoptotic Bcl-2 family proteins (average IC50, 3 umol/L), including Mcl-1 (IC50, 2.9 umol/L) and Bfl-1 (IC50, 5 umol/L)
[NAME] (AZD2281) | d9-L1700-01 | 763113-22-0, 894104-70-2, 937799-91-2, 1021843-02-6 | 10 mM | S1060 | PARP | Olaparib, AZD2281, KU0059436, AZD-2281 or KU-0059436 is a PARP inhibitor. AZD 2281 Olaparib (CAS 763113-22-0) is available with IC50: PARP-1= 0.005 μM, PARP-2= 0.001 μM & >99% HPLC.
[NAME] (AB1010) | d10-L1700-01 | 790299-79-5, 1048007-93-7 (methanesulfonate) | 10 mM | S1064 | [NAME], PDGFR, FGFR, FAK | Masitinib also known as Masivet, AB1010 is a tyrosine kinase, c-Kit, PDGFR, FGFR3, the FAK pathway inhibitor with IC50 of 150 ± 80, 200 ± 40 nM.
[NAME] | d11-L1700-01 | 957054-30-7, 957054-33-0 (dimethanesulfonate), 957054-54-5 (xTFA) | 10 mM | S1065 | PI3K | Inhibitor of Class I PI3 Kinase,p110a IC50=0.003uM,U87MG IC50=0.95μM.
SB 431542 | e1-L1700-01 | 301836-41-9, 1049727-65-2 (H2O) | 10 mM | S1067 | TGF-beta/[NAME] | SB-431542 is an inhibitor of activin receptor-like kinase (ALK)5 (the TGF-βtype I receptor) (IC50 = 94 nM).
Crizotinib (PF-02341066) | e2-L1700-01 | 877399-52-5, 877399-53-6 (acetate) | 10 mM | S1068 | c-Met, ALK | Inhibitor of the c-Met kinase and the NPM-ALK. [NAME] inhibited cell proliferation in ALK-positive ALCL cells (IC50s=30 nM).
ZSTK474 | e3-L1700-01 | 475110-96-4 | 10 mM | S1072 | PI3K | ZSTK474 is an inhibitor of PI3K γ (IC50 at 6 nM).
SB 216763 | e4-L1700-01 | 280744-09-4 | 10 mM | S1075 | GSK-3 | SB 216763 inhibited human GSK-3α with IC50s of 34 nM.
SB 203580 | e5-L1700-01 | 152121-47-6, 224047-03-4, 869185-85-3 (HCl) | 10 mM | S1076 | p38 MAPK | SB 203580 is a potent inhibitor of LPS-induced cytokine synthesis in the human [NAME] cell line THP-1 (IC50 = 50-100 nM).
SB 202190 | e6-L1700-01 | 152121-30-7, 350228-36-3 (HCl) | 10 mM | S1077 | p38 MAPK | P38 MAP (mitogen activated protein) Kinase inhibitor.
MK-2206 dihydrochloride | e7-L1700-01 | 1032350-13-2, 1032349-93-1 (free base), 1032349-77-1 (HCl) | 10 mM | S1078 | [NAME] | MK2206 an Akt inhibitor with IC50 at 8 nm, 2 mM, 65 mM for Akt1, Akt2 and Akt3, respectively is available on Selleck.
PD153035 HCl | e8-L1700-01 | 183322-45-4, 153436-54-5 (free base) | 10 mM | S1079 | EGFR | PD153035 is an inhibitor of EGFR, competitive with ATP. EGF Receptor: IC50 = 25 pM (Ki = 6 pM).
SU11274 | e9-L1700-01 | 658084-23-2 | 10 mM | [NAME] | c-Met | SU11274 is a c-Met inhibitor (IC50 at 0.012μM).
Vismodegib (GDC-0449) | e10-L1700-01 | 879085-55-9 | 10 mM | S1082 | Hedgehog, P-gp | GDC-0449 is a more potent novel and specific synthetic oral hedgehog pathway inhibitor with an IC50 of 3 nM.
[NAME] (PXD101) | e11-L1700-01 | 414864-00-9 | 10 mM | S1085 | HDAC | Belinostat also known as PXD101 is an HDAC inhibitor with IC50 of 27 nM.
Iniparib (BSI-201) | f1-L1700-01 | 160003-66-7 | 10 mM | S1087 | PARP | [NAME] (Iniparib, BSI201) is a potent PARP1 inhibitor with strong anti-neoplastic effect.
NVP-ADW742 | f2-L1700-01 | 475488-23-4 | 10 mM | S1088 | IGF-1R | IGF-1R inhibitor with an IC50 of 0.1 to 0.2 μM.
KU-55933 | f3-L1700-01 | 587871-26-9 | 10 mM | S1092 | ATM | ATM inhibitor with an IC50 of 13 nM and [NAME] of 2.2 nM.
PF-04217903 | f4-L1700-01 | 956905-27-4, 956906-93-7 (methanesulfonate), 1159490-81-9 (HCl) | 10 mM | S1094 | c-Met | MET inhibitor with an IC50 from 3.1 nM to142 nM.
[NAME] (NVP-LAQ824, Dacinostat) | f5-L1700-01 | 404951-53-7, 927176-79-2 (TFA) | 10 mM | S1095 | HDAC | [NAME] (NVP-LAQ824) is an HDAC inhibitor with an IC50 of 0.032 μM.
JNJ-26481585 | f6-L1700-01 | 875320-29-9, 875320-30-2 (TFA), 875320-31-3 (2HCl) | 10 mM | S1096 | HDAC | JNJ-26481585 is an orally bioavailable, second-generation, hydroxamic acid-based HDAC inhibitor with an IC50 of 2.43 nM for 5T33MMvt cells.
Rucaparib (AG-014699 , PF-01367338) | f7-L1700-01 | 459868-92-9, 283173-50-2 (free base) | 10 mM | S1098 | PARP | AG-014699 is a PARP inhibitor (Ki, 1.4 nmol/L).
[NAME] dihydrochloride (PTK787) | f8-L1700-01 | 212141-51-0, 212141-54-3 (free base) | 10 mM | S1101 | VEGFR, c-Kit, Flt | [NAME] (PTK787/ZK 222584) is a novel VEGFR and c-Kit tyrosine kinases and angiogenesis inhibitor with IC50 of 0.037, 0.077, 0.27 and 0.73 μM for KDR, Flt-1, [NAME] and c-Kit, respectively.
U0126-EtOH | f9-L1700-01 | 1173097-76-1, 109511-58-2 (FREE BASE) | 10 mM | S1102 | MEK | Inhibitor of both MEK1 and MEK2 with an IC50 of 72 nM and 58 nM respectively.
ZM-447439 | f10-L1700-01 | 331771-20-1 | 10 mM | S1103 | [NAME] | ZM-447439 is a poten, selective ATP-competitive [NAME] B kinase inhibitor with an IC50 of 50 nM, 1 μM and 250 nM for [NAME] B, A and C, respectively.
GDC-0879 | f11-L1700-01 | 905281-76-7 | 10 mM | S1104 | Raf | GDC-0879 is an B-Raf inhibitor ( EC50 = 0.75 µM).
LY294002 | g1-L1700-01 | 154447-36-6, 934389-88-5 (HCl) | 10 mM | S1105 | PI3K | PI3k inhibitor (cell IC50 about 10 μM) and a casein kinase II inhibitor.
Danusertib (PHA-739358) | g2-L1700-01 | 827318-97-8 | 10 mM | S1107 | [NAME], FGFR, Bcr-Abl, c-RET, [NAME] | PHA-739358 (Danusertib) is a pyrrolo-pyrazole and small molecule [NAME] kinases and Bcr-Abl kinase inhibitor with IC50 of 13, 79, and 61 nM for [NAME] A, B, and C, respectively.
TAE684 (NVP-TAE684) | g3-L1700-01 | 761439-42-3 | 10 mM | S1108 | ALK | ALK inhibitor with an IC50 between 2 and 10 nM.
BI 2536 | g4-L1700-01 | 755038-02-9, 876126-71-5 (H2O) | 10 mM | S1109 | PLK | Plk1 inhibitor with an IC50 of 0.83 nM.
Foretinib (GSK1363089, [NAME]) | g5-L1700-01 | 849217-64-7, 1332889-22-1 (H2O) | 10 mM | S1111 | c-Met, VEGFR | Foretinib (GSK1363089, [NAME]) is a novel MET and VEGFR2/KDR kinases inhibitor with an IC50 of 0.4 and 0.8 nM for MET and KDR, respectively.
SGX-523 | g6-L1700-01 | 1022150-57-7, 1072116-01-8 | 10 mM | S1112 | c-Met | SGX-523 is an exquisitely selective, ATP-competitive MET receptor [NAME] inhibitor with an IC50 of 4 nM for the inhibition of HGFR.
[NAME] | g7-L1700-01 | 943540-75-8, 1093204-17-1 (X methanesulfonate), 1093204-20-6 (XHCl) | 10 mM | S1114 | c-Met | [NAME] is a c-MET inhibitor with an IC50 of 4 nM.
PD 0332991 (Palbociclib) HCl | g8-L1700-01 | 827022-32-2, 571190-30-2 (free base) | 10 mM | S1116 | CDK | CDK inhibitor with an IC50 of 0.011 μM for Cdk4 and IC50 of 0.016 μM for Cdk6.
[NAME] | g9-L1700-01 | 956958-53-5 | 10 mM | S1118 | PI3K | [NAME] is a selective inhibitor of Class I PI3K isoforms.
[NAME] ([NAME]) | g10-L1700-01 | 849217-68-1,1140909-48-3 (L-(-)-Apple Acid) | 10 mM | S1119 | VEGFR, c-Met, Flt, Tie-2, c-Kit | [NAME] ([NAME], BMS-907351) is a potent multitargeted VEGFR2, Met, FLT3, Tie2, [NAME] and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and [NAME], respectively.
Everolimus (RAD001) | g11-L1700-01 | 159351-69-6, 1245613-55-1 | 10 mM | S1120 | mTOR | [NAME] also known as SDZ-RAD, Certican, Zortress, Afinitorm is TOR inhibitor available at Selleck with IC50 of 0.63 nM.
TW-37 | h1-L1700-01 | 877877-35-5 | 10 mM | S1121 | Bcl-2 | [NAME] family inhibitor,Ki value=290 nM.
Mocetinostat (MGCD0103) | h2-L1700-01 | 726169-73-9, 944537-89-7 (2BrH) | 10 mM | [NAME] | HDAC | MGCD0103 (Mocetinostat) is a potent HDAC inhibitor with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3, respectively.
Abiraterone (CB-7598) | h3-L1700-01 | 154229-19-3 | 10 mM | S1123 | P450 | Abiraterone is a CYP17 inhibitor (IC50 at 4 nM).
YM155 | h4-L1700-01 | 781661-94-7, 753440-91-4 (FREE BASE) | 10 mM | S1130 | Survivin | YM155 (YM 155, YM-155) is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.
INO-1001 | h5-L1700-01 | 3544-24-9, 220583-51-7 (TFA) | 10 mM | S1132 | PARP | INO-1001 (NSC 36962, SR 4294, WD 97-000835) is a novel potent PARP inhibitor with an IC50 of 3 nM.
MLN8237 (Alisertib) | h6-L1700-01 | 1028486-01-2, 1186318-95-5, 1028486-06-7 (sodium salt) | 10 mM | S1133 | [NAME] | MLN8237 (MLN-8237) is a selective [NAME] kinase A inhibitor with a median IC50 of 61 nM.
AT9283 | h7-L1700-01 | 896466-04-9, 896466-57-2 ((±)-Lactic acid), 896466-61-8 (HCl), 896466-55-0 (methanesulfonate) | 10 mM | S1134 | Bcr-Abl, JAK, [NAME] | AT9283 is a small molecule a multi-targeted c-ABL, JAK2, [NAME] and B inhibitor with of 4, 1.2, 1.1 and approximate 3 nM for Bcr-Abl (T3151), Jak2 and Jak3, aurora A and B, respectively.
Pemetrexed | h8-L1700-01 | 150399-23-8, 137281-23-3 (free base) | 10 mM | S1135 | DHFR, DNA/RNA Synthesis | Pemetrexed disodium (Alimta) is a thymidylate synthase, DHFR and glycinamide ribonucleotide formyltransferase inhibitor with an IC50 of 25, 34, 220 nM.
17-AAG (Tanespimycin) | h9-L1700-01 | 75747-14-7, 911710-03-7 (HCl) | 10 mM | S1141 | HSP | 17-AAG is a less toxic analogue of the geldanamycin which binds to [NAME] and alters its function.
17-DMAG HCl (Alvespimycin) | h10-L1700-01 | 467214-21-7, 467214-20-6 (free base) | 10 mM | S1142 | HSP | A selective Hsp90 inhibitor with a GI50 of 53 nM.
AG-490 | h11-L1700-01 | 133550-30-8 | 10 mM | S1143 | JAK, EGFR | AG 490 is a potent epidermal growth factor receptor kinase autophosphorylation inhibitor with an IC50 of 100 nM and 56.8 μM for EGFR and [NAME], respectively.
Ivacaftor (VX-770) | a1-L1700-02 | 873054-44-5, 1134822-09-5 (benzenesulfonate), 1134822-07-3 (H2O) | 10 mM | S1144 | CFTR | VX-770 is a CFTR potentiator with an IC50 of 43 ± 38 nM.
SNS-032 (BMS-387032) | a2-L1700-02 | 345627-80-7, 345627-90-9 (HCl) | 10 mM | S1145 | CDK | SNS-032 (BMS-387032) is a potent and selective cyclin-dependent kinases (CDK) 9, 7 and 2 inhibitor with IC50 of 4, 62 and 38 nM for [NAME], [NAME]/cyclin A and CDK7/Cyclin H.
Cyclopamine | a3-L1700-02 | 4449-51-8, 11051-96-0, 26108-61-2 | 10 mM | S1146 | Hedgehog | A [NAME] or hedgehog signaling pathway inhibitor.
Barasertib (AZD1152-HQPA) | a4-L1700-02 | 722544-51-6 | 10 mM | S1147 | [NAME] | AZD1152-HQPA is a highly potent and selective inhibitor of [NAME] (Ki, 0.36 nM)
[NAME] (Taxotere) | a5-L1700-02 | 114977-28-5, 148408-66-6 (3H2O) | 10 mM | S1148 | [NAME] | [NAME] (Taxotere) is an microtubule disassembly inhibitor with IC50 of a range of 0.31-100 ηM.
Gemcitabine HCl (Gemzar) | a6-L1700-02 | 122111-03-9, 95058-81-4 (free base) | 10 mM | S1149 | DNA/RNA Synthesis | Gemcitabine is an antimetabolites inhibiting DNA synthesis(cell IC50 of 0.06 µM).
Paclitaxel (Taxol) | a7-L1700-02 | 33069-62-4, 157069-30-2, 1203669-79-7 | 10 mM | S1150 | [NAME] | Paclitaxel also known as Taxol, [NAME], Nov-Onxol is a microtubule polymer stabilizer with an IC50 of 0.1 pM for human endothelial cells.
PLX-4720 | a8-L1700-02 | 918505-84-7 | 10 mM | S1152 | Raf | PLX-4720 is a B-raf inhibitor with IC50 of 160 nM.
Roscovitine (Seliciclib, CYC202) | a9-L1700-02 | 186692-46-6 | 10 mM | S1153 | CDK | Roscovitine also known as CYC202 & Seliciclib. Roscovitine with purity >99% & solubility DMSO is available.
SNS-314 | a10-L1700-02 | 1146618-41-8, 1057249-41-8 (FREE BASE) | 10 mM | S1154 | [NAME] | Inhibitor of [NAME] kinases A (IC50=9.0nM),B (IC50=31nM),and C (IC50=3.4nM)
NSC 74859 (S3I-201) | a11-L1700-02 | 501919-59-1 | 10 mM | S1155 | STAT | S3I-201 (NSC 74859) is a chemical probe inhibitor of Stat3 activity
Capecitabine (Xeloda) | b1-L1700-02 | 154361-50-9,158798-73-3, 958887-39-3 | 10 mM | S1156 | DNA/RNA Synthesis | Capecitabine (Xeloda) is an orally-administered chemotherapeutic agent (IC50 = 0.7~5 [NAME]) and prodrug of 5-fluorouracil which is a DNA synthesis inhibitor with an IC50 for 5.0 ± 1.8 μM.
ABT-751 | b2-L1700-02 | 141430-65-1, 141450-48-8 (HCl) | 10 mM | S1165 | [NAME] | [NAME] is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with an IC50 of about 1.5 and 3.4 µM in neuroblastoma and non-neuroblastoma cell lines.
[NAME] | b3-L1700-02 | 15663-27-1 | 10 mM | S1166 | DNA/RNA Synthesis | Cisplatin is a potent anticancer agent that blocks DNA synthesis.
CP-724714 | b4-L1700-02 | 537705-08-1 | 10 mM | S1167 | EGFR, [NAME] | HER-2 tyrosine kinase inhibitor, IC50 of 15 ng/ml
FG-4592 | [NAME] | 808118-40-3 | 10 mM | S1007 | HIF | FG-4592 is an HIF α prolyl hydroxylase inhibitor.
TGX-221 | b6-L1700-02 | 663619-89-4 | 10 mM | S1169 | PI3K | PI3Kβ (IC50=10nM)
WZ3146 | b7-L1700-02 | 1214265-56-1 | 10 mM | S1170 | EGFR | WZ3146 is an irreversiblely inhibitor against EGFR T790M.
CYC116 | b8-L1700-02 | 693228-63-6, 1067881-58-6 | 10 mM | S1171 | [NAME], VEGFR | [NAME] kinase/VEGFR2 inhibitor
JNJ 26854165 (Serdemetan) | b9-L1700-02 | 881202-45-5, 881202-79-5 (3HCl) | 10 mM | S1172 | p53 | [NAME] (JNJ 1, Serdemetan ) is an orally bioavailable, first-in-class small-molecule HDM2 antagonist with potential antineoplastic activity.
WZ4002 | b10-L1700-02 | 1213269-23-8 | 10 mM | S1173 | EGFR | WZ4002 is an EGFR T790M inhibitor (IC50<20nM).
BIIB021 | b11-L1700-02 | 848695-25-0, 848696-06-0 (XHCl), 848696-07-1 (methanesulfonate) | 10 mM | S1175 | HSP | Inhibitor of Hsp90 ([NAME]).
NPI-2358 (Plinabulin) | c1-L1700-02 | 714272-27-2, 1367709-16-7 (TFA) | 10 mM | S1176 | VDA | NPI-2358 is a novel vascular disrupting agent (VDA) with an IC50 of 15 nM against HT-29 cells.
PD98059 | c2-L1700-02 | 167869-21-8 | 10 mM | S1177 | MEK | PD 98059 is an inhibitor of MEK1 and MEK2 with IC50 values of 4 µM and 50 µM.
Regorafenib (BAY 73-4506) | c3-L1700-02 | 755037-03-7, 835621-07-3 (HCl), 835621-08-4 (methanesulfonate) | 10 mM | S1178 | [NAME], Raf, VEGFR | BAY 73-4506 (Regorafenib) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf.
WZ8040 | c4-L1700-02 | 1214265-57-2 | 10 mM | S1179 | EGFR | WZ8040 is an irreversiblely EGFR T790M inhibitor (IC50<10nM).
[NAME] | c5-L1700-02 | 284028-89-3 | 10 mM | S1180 | Wnt/beta-catenin | XAV 939 is a small molecule and selective Wnt pathway transcription factor β-catenin-mediated transcription inhibitor and axin stabilizing agent with IC50 of 11 and [NAME] for the inhibition of TNKS1 and TNKS2, respectively.
ENMD-2076 | c6-L1700-02 | 1291074-87-7 | 10 mM | S1181 | Flt, [NAME], VEGFR | ENMD-2076 (ENMD-981693, ENMD2076) is a antiangiogenic and [NAME] kinase inhibitor with IC50 of 3, 13, 350, 23, 40, 93 and 120 nM for Flt-3, AurA, [NAME], [NAME], KDR/VEGFR2 and FGFR1.
Danoprevir | c7-L1700-02 | 850876-88-9, 916881-67-9, 1001913-18-3, 1225266-12-5 | 10 mM | S1183 | Proteasome, HCV Protease | Danoprevir is a highly potent inhibitor of the NS3/4A protease.
[NAME] | c8-L1700-02 | 155213-67-5 | 10 mM | S1185 | HIV Protease | [NAME] is an inhibitor of HIV protease used to treat HIV infection and AIDS.
BIBR1532 | c9-L1700-02 | 321674-73-1 | 10 mM | S1186 | Telomerase | A selective telomerase inhibitor,IC50 of 93 nM.
PIK-90 | c10-L1700-02 | 677338-12-4 | 10 mM | S1187 | PI3K | PI3K inhibitor,IC50=11, 350, 18, and 58 for p110 α, β, γ and δ isoforms.
Anastrozole | c11-L1700-02 | 120511-73-1 | 10 mM | S1188 | Aromatase | Inhibits the enzyme aromatase
Aprepitant (MK-0869) | d1-L1700-02 | 170729-80-3 | 10 mM | S1189 | Substance P | Substance P antagonists (SPA).
Bicalutamide (Casodex) | d2-L1700-02 | 90357-06-5 | 10 mM | S1190 | Androgen Receptor, P450 | An oral non-steroidal anti-androgen.
Fulvestrant (Faslodex) | d3-L1700-02 | 129453-61-8 | 10 mM | S1191 | Estrogen/progestogen Receptor | Synthetic estrogen receptor antagonist (SERD)
Raltitrexed (Tomudex) | d4-L1700-02 | 112887-68-0 | 10 mM | S1192 | DNA/RNA Synthesis | Raltitrexed (Tomudex) is a thymidylate synthase inhibitor with an IC50 of 9 nM for the inhibition of L1210 cell growth.
Thalidomide | d5-L1700-02 | 50-35-1 | 10 mM | S1193 |  | Thalidomide was introduced as a sedative drug,immunomodulatory agent and also is investigated for treating symptoms of many cancers.
CUDC-101 | d6-L1700-02 | 1012054-59-9, 1012060-66-0 (L(+)-Tartaric Acid) | 10 mM | S1194 | HDAC, EGFR, [NAME] | CUDC-101 is a potent multitargeted HDAC, EGFR and HER2 inhibitor with IC50 of 4.4, 2.4, and 15.7 nM, respectively.
Exemestane | d7-L1700-02 | 107868-30-4 | 10 mM | S1196 | Aromatase | Exemestane was found to inhibit human placental aromatase with IC50 of 42 nM.
Finasteride | d8-L1700-02 | 98319-26-7, 222989-99-3 (acetate) | 10 mM | S1197 | 5-alpha Reductase | Inhibitor of steroid Type II 5α-reductase
Irinotecan | d9-L1700-02 | 97682-44-5 | 10 mM | S1198 | Topoisomerase | Irinotecan (Camptosar, Campto, CPT-11) is a topoisomerase I inhibitor with an IC50 of 15.8 and 5.17 μM for LoVo cells and HT-29 cells, respectively.
Cladribine | d10-L1700-02 | 4291-63-8 | 10 mM | S1199 | DNA/RNA Synthesis | Cladribine ([NAME]) is an adenosine deaminase inhibitor with an IC50 of about 0.2 μM.
Decitabine | d11-L1700-02 | 2353-33-5, 879492-56-5 (HCl), 879492-57-6 (monomethanesulfonate) | 10 mM | S1200 | DNA/RNA Synthesis | Decitabine (NSC 127716, Dacogen, DAC) is an available nucleoside-based DNA methyltransferase (DNMT) inhibitor with IC50 of 490, 400 and 100 nM for A549, LoVo and LoVo-DX cell lines.
Dutasteride | e1-L1700-02 | 164656-23-9 | 10 mM | S1202 | 5-alpha Reductase | 5-alpha-reductase inhibitor
PIK-75 | e2-L1700-02 | 372196-77-5, 372196-67-3 (free base) | 10 mM | S1205 | PI3K, DNA-PK | PIK-75 Hydrochloride is a hydrochloride salt form of PIK-75, which is a preferential p110α/γ forms of PI3K inhibitor with IC50 of 6, 1300, 76, 510 nM for p110α, [NAME], [NAME], p110δ, respectively.
Bisoprolol | e3-L1700-02 | 104344-23-2 | 10 mM | S1206 | Adrenergic Receptor | A selective type β1 adrenergic receptor blocker
Tivozanib (AV-951) | e4-L1700-02 | 475108-18-0, 682745-41-1 (ClH.H2O), 682745-43-3 (HCL) | 10 mM | S1207 | VEGFR, c-Kit, PDGFR | Tivozanib also known as AV-951 is an orally bioavailable potent VEGFR-1, 2 and 3, c-Kit and PDGFR inhibitor with IC50 of 0.21, 0.16, 0.24, 1.63 and 1.72 nM, respectively.
[NAME] ([NAME]) | e5-L1700-02 | 25316-40-9, 23214-92-8 (free base), 1246449-85-3 (4-methylbenzenesulfonate) | 10 mM | S1208 | Topoisomerase | [NAME] is a topoisomerase II inhibitor with IC50 of 1 and 2 μM for the inhibition of MCF-7 and MDA-MB231.
Adrucil (Fluorouracil) | e6-L1700-02 | 51-21-8 | 10 mM | S1209 | DNA/RNA Synthesis | Adrucil (Fluorouracil) belongs to the family of drugs called antimetabolites.
Imiquimod | e7-L1700-02 | 99011-02-6, 99011-78-6 (HCl), 896106-16-4 (Maleic acid) | 10 mM | S1211 |  | [NAME] ([NAME]) is a novel synthetic agent with immune response modifying activity.
Bendamustine HCL | e8-L1700-02 | 3543-75-7 | 10 mM | S1212 |  | Bendamustine inhibits SU-DHL-1 cell proliferation with IC50 at 50 μm.
Nelarabine (Arranon) | e9-L1700-02 | 121032-29-9 | 10 mM | S1213 | DNA/RNA Synthesis | Nelarabine (Arranon) performes growth inhibitory activity (IC50= 1.61 µM) against MOLT-4 cells.
Bleomycin sulfate | e10-L1700-02 | 9041-93-4 | 10 mM | S1214 | DNA/RNA Synthesis | A glycopeptide antibiotic produced by the bacterium Streptomyces verticillus.
Carboplatin | e11-L1700-02 | 41575-94-4 | 10 mM | S1215 | DNA/RNA Synthesis | Carboplatin performed growth inhibitory activity in IGROV1 and [NAME] cells (IC50 of 25 and 30 mg/l,respectively).
Dovitinib (TKI-258) | f1-L1700-02 | 405169-16-6, 804551-71-1 | 10 mM | S1018 | FLT3 | [NAME] (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively.
Clofarabine | f2-L1700-02 | 123318-82-1 | 10 mM | S1218 | DNA/RNA Synthesis | Inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase
OSI-930 | f3-L1700-02 | 728033-96-3 | 10 mM | S1220 | [NAME], VEGFR | OSI-930 is an inhibitor of the receptor tyrosine kinases [NAME] (IC50:9.5nM) and VEGFR-2 (IC50:10.1nM).
Dacarbazine (DTIC-Dome) | f4-L1700-02 | 4342-03-4 | 10 mM | S1221 | DNA/RNA Synthesis | Dacarbazine (DTIC-Dome) is an antineoplastic chemotherapy drug used in the treatment of various cancers.
[NAME] | f5-L1700-02 | 149003-01-0 | 10 mM | S1222 |  | A cardioprotective agent
[NAME] | f6-L1700-02 | 56390-09-1 | 10 mM | S1223 | Topoisomerase | [NAME] (Ellence) is an anthracyclin antibiotics and a DNA topoisomerase II inhibitor with an IC50 of 12 μg/ml on an estrogen-receptor- positive ER (+) hyperdiploid EAT cell line.
[NAME] (Eloxatin) | f7-L1700-02 | 61825-94-3 | 10 mM | S1224 | DNA/RNA Synthesis | [NAME] (Eloxatin) is a 1,2-diaminocyclohexane (DACH) carrier ligand-based groups of platinum antitumor agent with IC50 of median 1.3, 6.2 and 1.5 mM for [NAME], HT29, respectively.
Etoposide ([NAME]) | f8-L1700-02 | 33419-42-0, 35317-32-9, 51854-34-3 | 10 mM | S1225 | Topoisomerase | Etoposide (Etopophos) is a Topoisomerase II inhibitor (IC50 = 59.2 μM).
Ku-0063794 | f9-L1700-02 | 938440-64-3 | 10 mM | S1226 | mTOR | Ku-0063794 is a mTOR inhibitor, IC50 ~10 nM for mTORC1 and mTORC2, respectively.
[NAME] ([NAME]) | f10-L1700-02 | 82640-04-8 | 10 mM | S1227 | Estrogen/progestogen Receptor | A selective estrogen receptor modulator (SERM). [NAME] inhibited the proliferation of the human breast cancer cell line, MCF-7, with IC50=0.2 nM
Idarubicin HCl | f11-L1700-02 | 57852-57-0, 58957-92-9 | 10 mM | S1228 | Topoisomerase | Idarubicin is the anthracycline antibiotic and target DNA topoisomerase II (topo II). MCF-7 cells were sensitive to idarubicin, with an IC 50 value for growth inhibition of 0.01 μM
Fludarabine Phosphate (Fludara) | g1-L1700-02 | 75607-67-9 | 10 mM | S1229 | DNA/RNA Synthesis | Fludarabine Phosphate (Fludara, 2-F-ara-AMP, FAMP) is a nucleoside analogue and formulated as the monophosphate form of F-ara-AMP(fludarabine, IC50 < 3 μM).
Perifosine | g2-L1700-02 | 157716-52-4 | 10 mM | S1037 | [NAME] | Perifosine ([NAME]) is a novel [NAME] inhibitor with IC50 of 4.7 [NAME]
Topotecan HCl | g3-L1700-02 | 119413-54-6 | 10 mM | S1231 | Topoisomerase | Topotecan Hydrochloride (Hycamtin) is a topoisomerase I inhibitor with an IC50 of 13 and 2 nM for MCF-7 Luc cells and DU-145 Luc cells.
2-Methoxyestradiol | g4-L1700-02 | 362-07-2,39-20-7 (H2SO4) | 10 mM | S1233 | HIF | 2-methoxyestradiol (2ME2) is a natural metabolite of estrogen that is known to inhibit [NAME] alpha with an IC50 of 0.71 ± 0.11 μM for the inhibition of BPAEC migration.
Letrozole | g5-L1700-02 | 112809-51-5 | 10 mM | S1235 | Aromatase | Letrozole is an Aromatase inhibitor. CGS 20267 is a new non-steroidal compound which potently inhibits aromatase in vitro (IC50 of 11.5 nM) and in vivo (ED50 of 1–3 μg/kg p.o.)  Pricing
Leucovorin Calcium | g6-L1700-02 | 6035-45-6 | 10 mM | S1236 |  | Leucovorin is a reduced folic acid.
Methazolastone | g7-L1700-02 | 85622-93-1 | 10 mM | S1237 |  | Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer.
Vincristine | g8-L1700-02 | 2068-78-2 | 10 mM | S1241 | [NAME] | [NAME] is a microtubule function inhibitor with IC50 of 10.4 ± 1.1, 28.1 ± 3.4, 22.4 ± 2.1 µM for HL-60, Bel7402, HO-8910, respectively.
Agomelatine | g9-L1700-02 | 138112-76-2, 1176316-99-6 (HCl), 824393-18-2 (L(+)-Tartaric acid) | 10 mM | S1243 | 5-HT Receptor | Agomelatine is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.
Amuvatinib (MP-470) | g10-L1700-02 | 850879-09-3 | 10 mM | S1244 | c-Met, c-Kit, PDGFR, [NAME], c-RET | [NAME] is a multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Met, c-Kit, PDGFRalpha, Flt3, and c-Ret and with an IC50 of median 5 μM.
Leflunomide | g11-L1700-02 | 75706-12-6, 210165-51-8 | 10 mM | S1247 |  | Immunosuppressant agent. Its active metabolite is A77 1726 (RS-61980).
[NAME] | h1-L1700-02 | 443797-96-4 | 10 mM | S1249 | CDK, [NAME] | A Dual Inhibitor of Cyclin-Dependent Kinases and [NAME]. In vitro kinase IC50:CDK1/Cyclin B(0.009 umol/L), Aurora-A(0.011 umol/L).
[NAME] hydrate | h2-L1700-02 | 209216-23-9 | 10 mM | S1252 |  | [NAME] hydrate belongs to the family of medicines called antivirals.
STF-62247 | h3-L1700-02 | 315702-99-9 | 10 mM | S1041 |  | STF-62247 is selectively toxic and growth inhibitory to renal cells lacking VHL
Nepafenac | h4-L1700-02 | 78281-72-8 | 10 mM | S1255 |  | Nepafenac is a non-steroidal anti-inflammatory drug (NSAID).
Rufinamide (Banzel) | h5-L1700-02 | 106308-44-5 | 10 mM | S1256 | Sodium Channel | Rufinamide, a triazole derivative, is an anticonvulsant medication.
Posaconazole | h6-L1700-02 | 171228-49-2, 177571-33-4, 1198769-38-8 (H2O) | 10 mM | S1257 |  | Posaconazole is a triazole antifungal drug.
Prasugrel (Effient) | h7-L1700-02 | 150322-43-3, 389574-19-0 (HCl), 389574-20-3 (Maleic acid) | 10 mM | S1258 | [NAME] | A novel platelet inhibitor
Ramelteon (TAK-375) | h8-L1700-02 | 196597-26-9 | 10 mM | S1259 |  | Ramelteon is a melatonin receptor agonist with both high affinity for melatonin [NAME] (IC50 =28.5 ± 8.55 pM)and MT2 (20.1 ± 9.25 pM)receptors and selectivity over the MT3 receptor.
[NAME] HCl (Cinacalcet hydrochloride) | h9-L1700-02 | 364782-34-3, 226256-56-0 (free base), 1025064-29-2 (acetate) | 10 mM | S1260 | CaSR | [NAME] (Cinacalcet hydrochloride) represents a new class of compounds for the treatment of hyperparathyroidism.
Celecoxib | h10-L1700-02 | 169590-42-5,184007-95-2, 194044-54-7 | 10 mM | S1261 | COX | COX-2 inhibitor,IC50=0.04uM
BMS-708163 ([NAME]) | h11-L1700-02 | 1146699-66-2 | 10 mM | S1262 | Gamma-secretase | γ-secretase inhibitor (GSI) (IC50 =0.3 nM)
Triptolide | a1-L1700-03 | 38748-32-2 | 10 mM | S3604
WYE-354 | a2-L1700-03 | 1062169-56-5 | 10 mM | S1266 | mTOR | WYE-354 is a mTOR inhibitor with an IC50 of 5 nM.
IC-87114 | a3-L1700-03 | 371242-69-2 | 10 mM | S1268 |  | IC-87114 was the first isoform-selective PI3K inhibitor : p110δ (IC50 = 0.13 µM) vs. p110α (IC50 = 200 µM), [NAME] (IC50 = 16 µM) and [NAME] (IC50 = 61 µM).
Acarbose | a4-L1700-03 | 56180-94-0, 1221158-13-9 (xH2O4S) | 10 mM | S1271 |  | Acarbose is an anti-diabetic drug used to treat type 2 diabetes mellitus and, in some countries, prediabetes.
[NAME] | a5-L1700-03 | 106685-40-9, 911110-93-5 (sodium salt) | 10 mM | S1276 |  | [NAME] is a third-generation topical retinoid primarily used in the treatment of acne.
Altretamine (Hexalen) | a6-L1700-03 | 645-05-6, 2975-00-0 (HCl) | 10 mM | S1278 |  | Altretamine (Hexalen) is an anti-neoplastic agent.
Amisulpride | a7-L1700-03 | 71675-85-9, 81342-13-4 (HCl) | 10 mM | S1280 | Dopamine Receptor | Amisulpride is an atypical antipsychotic used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder.
Asenapine | a8-L1700-03 | 65576-45-6, 135883-08-8 (Maleic acid) | 10 mM | S1283 | Adrenergic Receptor, 5-HT Receptor | Asenapine ([NAME]) is a new atypical antipsychotic used for the treatment of schizophrenia and acute mania associated with bipolar disorder .
Benazepril hydrochloride | a9-L1700-03 | 86541-74-4, 86541-75-5 (free base) | 10 mM | S1284 | RAAS | Benazepril is a medication used to treat high blood pressure.
Budesonide | a10-L1700-03 | 51333-22-3 | 10 mM | S1286 |  | Budesonide is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis.
Bumetanide | a11-L1700-03 | 28395-03-1, 28434-74-4 (sodium salt) | 10 mM | S1287 |  | Bumetanide (Bumex) is a loop diuretic of the sulfamyl category to treat heart failure.
Camptothecin | b1-L1700-03 | 7689-03-4 | 10 mM | S1288 | Topoisomerase | Camptothecin (CPT) is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I (topo I) with an IC50 and IC70 of 50 nM and 0. 225 μM .
[NAME] | b2-L1700-03 | 61422-45-5 | 10 mM | S1289 | Antimetabolites | [NAME] (INN) is a pyrimidine analogue used as an antineoplastic agent.
Cetirizine Dihydrochloride | b3-L1700-03 | 83881-52-1, 83881-52-1 (2HCl) | 10 mM | S1291 | Histamine Receptor | Cetirizine is an antihistamine.
Cilnidipine | b4-L1700-03 | 132203-70-4 | 10 mM | S1293 | Calcium Channel | Cilnidipine is a calcium channel blocker.
Cilostazol | [NAME] | 73963-72-1 | 10 mM | S1294 | PDE | Cilostazol is a medication used in the alleviation of the symptom of intermittent claudication in individuals with peripheral vascular disease.
Epothilone A | b6-L1700-03 | 152044-53-6, 1285540-20-6 (2H2O) | 10 mM | S1297 | [NAME] | Epothilone A is a new kind of microtubule function inhibitor with an IC50 of 4.4 nM for tubulin polymerization and cytotoxicity.
Floxuridine | b7-L1700-03 | 50-91-9 | 10 mM | S1299 | DNA/RNA Synthesis | Floxuridine (FUDR, FdUrd, [NAME]) is a prodrugs of floxuridine and an oncology drug with an GI50 of 5.1 μM for the inhibition of MDCK/PEPT1.
Ftorafur | b8-L1700-03 | 17902-23-7 | 10 mM | S1300 | DNA/RNA Synthesis | Ftorafur is a substance being used in the treatment of some types of cancer.
Ifosfamide | b9-L1700-03 | 3778-73-2, 36341-88-5, 84711-20-6 | 10 mM | S1302 | DNA/RNA Synthesis | Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer.
[NAME] | b10-L1700-03 | 595-33-5 | 10 mM | S1304 | Androgen Receptor | [NAME] is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HegG2.
[NAME] | b11-L1700-03 | 50-44-2, 6112-76-1 (HCl) | 10 mM | S1305 | DNA/RNA Synthesis | [NAME] is a drug used to treat leukemia.
Streptozotocin (Zanosar) | c1-L1700-03 | 18883-66-4, 11006-80-7, 37793-00-3, 132769-73-4 | 10 mM | S1312 |  | Streptozotocin (Streptozocin, Zanosar, STZ) is a naturally occurring chemical used in cancer chemotherapy and Type 1 diabetes treatment.
[NAME]Zoledronate) | c2-L1700-03 | 118072-93-8 | 10 mM | S1314 | PKC | A potent nitrogen-containing bisphosphonates.It inhibited proliferation of human foetal osteoblastic cell line (hFOB) with an IC50 of 40 μM.
Dexamethasone | c3-L1700-03 | 50-02-2 | 10 mM | S1322 | IL Receptor | Dexamethasone is an anti-inflammatory and immunosuppressant.
Doxazosin mesylate | c4-L1700-03 | 77883-43-3, 74191-85-8 (free base) | 10 mM | S1324 | Adrenergic Receptor | [NAME] mesylate ([NAME]) is an alpha-1 adrenergic receptor blocker.
Etodolac ([NAME]) | c5-L1700-03 | 41340-25-4, 150975-87-4 (monosodium salt) | 10 mM | S1328 | COX | Etodolac is a nonsteroidal anti-inflammatory drug.
Etomidate | c6-L1700-03 | 33125-97-2, 53188-20-8 (HCl) | 10 mM | S1329 | GABA Receptor | Etomidate is a GABAA receptors agonist at GABAA receptors.
Fluconazole | c7-L1700-03 | 86386-73-4, 155347-36-7 (H2O), 159532-41-9 (methanesulfonate) | 10 mM | S1331 |  | Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
[NAME] | c8-L1700-03 | 78755-81-4 | 10 mM | [NAME] | GABA Receptor | Flumazenil is a benzodiazepine antagonist.
[NAME] | c9-L1700-03 | 59333-67-4, 56296-78-7 | 10 mM | S1333 | 5-HT Receptor | Fluoxetine (Prozac, Sarafem) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI)class.
Gabapentin Hydrochloride | c10-L1700-03 | 60142-95-2, 60142-96-3 (free base) | 10 mM | S1338 | GABA Receptor | [NAME] is a GABA analogue.
Gatifloxacin | c11-L1700-03 | 112811-59-3, 316819-28-0 (methanesulfonate), 121577-32-0 (HCl) | 10 mM | S1340 |  | Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family.
Glimepiride | d1-L1700-03 | 93479-97-1 | 10 mM | S1344 | DPP-4 | Glimepiride is a medium-to-long acting sulfonylurea anti-diabetic drug.
Granisetron HCl | d2-L1700-03 | 107007-99-8, 109889-09-0 (free base) | 10 mM | S1345 | 5-HT Receptor | Granisetron is a serotonin 5-HT3 receptor antagonist
Ivermectin | d3-L1700-03 | 70288-86-7, 71827-03-7 | 10 mM | S1351 |  | Ivermectin is a broad-spectrum antiparasitic medication.
TG100-115 | d4-L1700-03 | 677297-51-7, 677297-55-1 (2HCL) | 10 mM | S1352 | PI3K | TG100–115 is [NAME] γ and -δ inhibitor (IC50 = 83 and 235 nM, respectively)
Ketoconazole | d5-L1700-03 | 65277-42-1, 142128-59-4 | 10 mM | S1353 | P450 | [NAME] is a synthetic broad-spectrum antifungal agent.
Lansoprazole | d6-L1700-03 | 103577-45-3, 226904-00-3 (sodium salt) | 10 mM | S1354 | [NAME] | [NAME] is a proton-pump inhibitor (PPI) which prevents the stomach from producing gastric acid.
Lidocaine (Alphacaine) | d7-L1700-03 | 137-58-6 | 10 mM | S1357 | Histamine Receptor | Lidocaine is a common local anesthetic and antiarrhythmic drug.
Loratadine | d8-L1700-03 | 79794-75-5, 444995-23-7 (HCl) | 10 mM | S1358 | Histamine Receptor | Loratadine (Claritin) is an antihistamine drug used to treat allergies.
GSK1059615 | d9-L1700-03 | 958852-01-2, 1356195-42-0 (H2O . Na) | 10 mM | S1360 | PI3K, mTOR | GSK1059615 is a pan-PI3K reversible inhibitor,IC50:PI3Kα(0.4 nM), β (0.6 nM),γ (5 nM),δ (2 nM) and mTOR(12 nM).
MGCD-265 | d10-L1700-03 | 875337-44-3 | 10 mM | S1361 | c-Met, VEGFR, Tie-2 | MGCD-265 is a multi-targeted kinase inhibitor, which targets the c-MET, VEGFR1, VEGFR2, VEGFR3, Tie-2 and [NAME] receptor tyrosine kinases.
ON-01910 | d11-L1700-03 | 1225497-78-8 | 10 mM | S1362 | PLK | ON-01910 is a non-ATP-competitive small molecule Plk1inhibitor with an IC50 of 9 nM.
Ki8751 | e1-L1700-03 | 228559-41-9 | 10 mM | S1363 | VEGFR, c-Kit, PDGFR | [NAME] is a potent, selective VEGFR-2 tyrosine kinase inhibitor with IC50 of 0.9 nM, 40, 67, 170 nM for VEGF-2, c-Kit, PDGFRα and FGFR-2, respectively.
Epothilone B (EPO906) | e2-L1700-03 | 152044-54-7 | 10 mM | S1364 | [NAME] | Epothilone B is a new kind of cancer drugs and microtubule function inhibitor with an IC50 of 3.5 nM.
BMS-707035 | e3-L1700-03 | 729607-74-3 | 10 mM | S1366 | Integrase | BMS-707035 is an HIV-1 integrase (IN) inhibitor.
Biapenem | e4-L1700-03 | 120410-24-4 | 10 mM | S1370 |  | Biapenem is a carbapenem antibiotic.
[NAME] | e5-L1700-03 | 103060-53-3, 500872-31-1 | 10 mM | S1373 |  | Daptomycin is a novel lipopeptide antibiotic.
[NAME] | e6-L1700-03 | 364622-82-2, 148016-81-3 (free base) | 10 mM | S1374 |  | [NAME] (doripenem monohydrate) is an ultra-broad spectrum injectable antibiotic.
Dorzolamide HCL | e7-L1700-03 | 130693-82-2, 120279-96-1 (free base) | 10 mM | S1375 | Carbonic Anhydrase | Dorzolamide (Trusopt) is a carbonic anhydrase inhibitor.
MLN9708 | e8-L1700-03 | 1201902-80-8 | 10 mM | S2181 | Proteasome | MLN9708 is an orally bioavailable second generation proteasome inhibitor with potential antineoplastic activity.
Gestodene | e9-L1700-03 | 60282-87-3, 110541-55-4 | 10 mM | S1376 | Estrogen/progestogen Receptor | Gestodene is a progestogen hormonal contraceptive.
Drospirenone | e10-L1700-03 | 67392-87-4 | 10 mM | S1377 | Estrogen/progestogen Receptor | Drospirenone is a synthetic progestin that is an analog to spironolactone.
Isotretinoin | e11-L1700-03 | 4759-48-2 | 10 mM | S1379 | Hydroxylase | Isotretinoin is used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more.
Lopinavir (ABT-378) | f1-L1700-03 | 192725-17-0 | 10 mM | S1380 | HIV Protease | Lopinavir is an inhibitor of the HIV protease.
Mianserin hydrochloride | f2-L1700-03 | 21535-47-7, 24219-97-4 (free base) | 10 mM | S1382 | Histamine Receptor | [NAME] is a psychoactive drug of the tetracyclic antidepressant.
Minoxidil | f3-L1700-03 | 38304-91-5, 16317-69-4 | 10 mM | S1383 | Lysyl Hydroxylase | Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth.
Mizoribine (Bredinin) | f4-L1700-03 | 50924-49-7 | 10 mM | S1384 | DNA/RNA Synthesis | Mizoribine (Bredinin) is an imidazole nucleoside and an immunosuppressive agent with an IC50 of approximately 100 [NAME]
Naftopidil Dihydrochloride | f5-L1700-03 | 57149-08-3, 57149-07-2 (free base) | 10 mM | S1387 | Adrenergic Receptor | [NAME] is an antihypertensive agent.
Omeprazole (Prilosec) | f6-L1700-03 | 73590-58-6 | 10 mM | S1389 | [NAME], ATPase | Omeprazole (Prilosec) is a proton pump inhibitor used in the treatment of dyspepsia.
Pelitinib (EKB-569) | f7-L1700-03 | 257933-82-7 | 10 mM | S1392 | EGFR | Pelitinib is a 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity.
Resveratrol | f8-L1700-03 | 501-36-0, 31100-06-8, 1337923-22-4 | 10 mM | S1396 | Sirtuin | Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects .
Rocuronium bromide | f9-L1700-03 | 119302-91-9, 143558-00-3 (free base) | 10 mM | S1397 | AChR | Rocuronium is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant.
Stavudine | f10-L1700-03 | 3056-17-5, 134624-73-0 (sodium salt) | 10 mM | [NAME] | Reverse Transcriptase | [NAME] is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV.
Tenofovir (Viread) | f11-L1700-03 | 147127-20-6, 206184-49-8 (H2O), 1236287-04-9 (Maleic acid) | 10 mM | S1401 | Reverse Transcriptase | Tenofovir belongs to nucleotide analogue reverse transcriptase inhibitors (nRTIs).
Trilostane | g1-L1700-03 | 13647-35-3, 27107-98-8, 28414-46-2 | 10 mM | S1404 | Dehydrogenase | Trilostane is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
Bimatoprost | g2-L1700-03 | 155206-00-1 | 10 mM | S1407 |  | Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.
Linezolid (Zyvox) | g3-L1700-03 | 165800-03-3 | 10 mM | S1408 |  | [NAME] is a synthetic antibiotic used for the treatment of serious infections.
[NAME] hydrochloride (Uroxatral) | g4-L1700-03 | 81403-68-1, 81403-80-7 (free base) | 10 mM | S1409 | Adrenergic Receptor | Alfuzosin (Uroxatral) is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).
AS-605240 | g5-L1700-03 | 648450-29-7 | 10 mM | S1410 | PI3K | AS-605240 is a PI3K γ inhibitor (IC50 at 8 nM).
Clopidogrel (Plavix) | g6-L1700-03 | 120202-66-6, 113665-84-2 (free base) | 10 mM | S1415 | [NAME] | Clopidogrel is an oral, thienopyridine class antiplatelet agent.
[NAME] | g7-L1700-03 | 99873-43-5 | 10 mM | S1422 | HDAC | Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8 (IC50 at 16.9 ,2.47 and 1.46 μM, respectively).
Y-27632 2HCl | g8-L1700-03 | 129830-38-2, 146986-50-7 | 10 mM | S1049 | ROCK | Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM.
Ranolazine dihydrochloride | g9-L1700-03 | 95635-56-6, 95635-55-5 (free base) | 10 mM | S1425 | Calcium Channel | Ranolazine (Ranexa), is an antianginal medication.
Repaglinide | g10-L1700-03 | 135062-02-1, 847829-40-7 (sodium salt), 172041-25-7 (calcium salt) | 10 mM | S1426 | Potassium Channel | Repaglinide is for the treatment of type II diabetes.
Risedronate sodium | g11-L1700-03 | 115436-72-1, 1159813-51-0 (free base) | 10 mM | S1428 |  | Risedronate sodium is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone.
Elesclomol | h1-L1700-03 | 488832-69-5, 874477-51-7 (disodium salt) | 10 mM | S1052 | HSP (e.g. [NAME]) | Elesclomol (STA-4783) is a novel potent oxidative stress inducer that illicits pro-apoptosis events among tumor cells..
Sildenafil citrate | h2-L1700-03 | 171599-83-0, 139755-83-2 (FREE BASE) | 10 mM | S1431 | PDE | Sildenafil citrate is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH).
Sumatriptan succinate | h3-L1700-03 | 103628-48-4, 103628-62-2 (HCl) | 10 mM | S1432 | 5-HT Receptor | Sumatriptan succinate (Imitrex, Imigran) is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Nutlin-3 | h4-L1700-03 | 890090-75-2 | 10 mM | S1061 | Mdm2 | Nutlin-3 is a potent and selective Mdm2 antagonist with IC50 of 90 nM.
Topiramate | h5-L1700-03 | 97240-79-4, 1103510-60-6 | 10 mM | S1438 | Carbonic Anhydrase | Topiramate (Topamax) is an anticonvulsant drug.
Tranilast (SB 252218) | h6-L1700-03 | 53902-12-8, 104931-56-8 (sodium salt) | 10 mM | S1439 |  | Tranilast (Rizaben) is an antiallergic drug.
Venlafaxine | h7-L1700-03 | 99300-78-4, 93413-69-5 (free base) | 10 mM | S1441 | 5-HT Receptor | Venlafaxine (Effexor, [NAME]) is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI).
Voriconazole | h8-L1700-03 | 137234-62-9, 173967-54-9 | 10 mM | S1442 | P450 | Voriconazole (VFEND) is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections.
Zileuton | h9-L1700-03 | 111406-87-2, 118569-21-4 (sodium salt) | 10 mM | S1443 |  | Zileuton (ZYFLO) is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation.
Ziprasidone hydrochloride | h10-L1700-03 | 122883-93-6, 138982-67-9 (ClH.H2O), 146939-27-7 (free base) | 10 mM | S1444 |  | Ziprasidone was the fifth atypical antipsychotic.
Zonisamide | h11-L1700-03 | 68291-97-4, 68291-98-5 (sodium salt) | 10 mM | S1445 |  | Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive.
Aurora A Inhibitor I | a1-L1700-04 | 1158838-45-9 | 10 mM | S1451 | [NAME] | Aurora A Inhibitor I is a selective [NAME] A inhibitor ([NAME]: IC50 at 0.0034 μM; [NAME]: IC50 at 3.4 μM), (B / A ratio=1000).
Ispinesib (SB-715992) | a2-L1700-04 | 336113-53-2, 514820-03-2 (methanesulfonate), 514820-04-3 (HCl) | 10 mM | S1452 | Kinesin | Ispinesib (SB 715992) is a potent mitotic kinesin KSP (Eg5) inhibitor with a [NAME] and an IC50 of 0.6 and 4.1 nM, respectively.
Tipifarnib (Zarnestra) | a3-L1700-04 | 192185-72-1 | 10 mM | S1453 | Farnesyltransferase, [NAME] | Tipifarnib is a potent and specific farnesyltransferase inhibitor with an IC50 of 0.6 nM.
PHA-680632 | a4-L1700-04 | 398493-79-3 | 10 mM | S1454 | [NAME] | PHA-680632 is the first representative of a new class of [NAME] inhibitors (Aurora A/B/C IC50 at 27,135 and 120 nM, respectively).
[NAME] (SB-207499) | a5-L1700-04 | 153259-65-5, 308328-52-1 (sodium salt) | 10 mM | S1455 | PDE | [NAME] ([NAME], SB-207499) is among the first of a new generation of PDE4 inhibitors (Ki ≈100 nM).
[NAME] (ZD4054) | a6-L1700-04 | 186497-07-4 | 10 mM | S1456 | ETA Receptor | [NAME] (ZD4054) is an orally administered, potent and specific ETA-receptor (endothelin A receptor) antagonist (IC50 = 21 nM).
AUY922 (NVP-AUY922) | a7-L1700-04 | 747412-49-3, 1051919-21-1 (methanesulfonate), 1051919-22-2 (HCl) | 10 mM | S1069 | HSP (e.g. [NAME]) | NVP-AUY922 (VER-52296) is a highly potent HSP90 inhibitor for HSP90α and HSP90β with IC50 of 13 nM and 21 nM, respectively.
SP600125 | a9-L1700-04 | 129-56-6, 67072-00-8 (potassium salt) | 10 mM | S1460 | JNK | SP600125 is a JNK inhibitor with IC50=40 nM for JNK-1 and [NAME] and 90 nM for JNK-3.
PHA-665752 | a10-L1700-04 | 477575-56-7, 1262750-60-6(HCl) | 10 mM | S1070 | c-Met | PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9 nM.
Ofloxacin (Floxin) | a11-L1700-04 | 82419-36-1, 118120-51-7 (XHCl) | 10 mM | S1463 | Topoisomerase | Ofloxacin is a synthetic broad-spectrum antimicrobial agent.
Moxifloxacin hydrochloride | b1-L1700-04 | 186826-86-8, 151096-09-2 (free base) | 10 mM | S1465 | Topoisomerase | [NAME] (Avelox, [NAME]) is a fourth generation synthetic fluoroquinolone antibacterial agent.
TSU-68 | b2-L1700-04 | 252916-29-3, 251356-54-4 (sodium salt) | 10 mM | S1470 | VEGFR, PDGFR , FGFR | A novel multiple receptor tyrosine kinase inhibitor, VEGF-R1, PDGF-Rβ and FGF-R1 with IC50 values of 2.1 µM, 8 nM and 1.2 µM, respectively.
GSK429286A | b3-L1700-04 | 864082-47-3 | 10 mM | S1474 | ROCK | GSK429286A is a cell-permeable, selective Rho-associated kinase (ROCK) inhibitor with an IC50 of 14 nM.
AS703026 | b4-L1700-04 | 1236699-92-5, 1236361-78-6 (HCl) | 10 mM | S1475 | MEK | AS703026 is a novel, selective, orally bioavailable MEK1/2 inhibitor (cell IC50 ranging from 0.005 to 2 µM).
SB 525334 | [NAME] | 356559-20-1 | 10 mM | S1476 | TGF-beta/[NAME] | SB525334 is a selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC50 = 14.3 nM).
VX-222 | b6-L1700-04 | 1026785-55-6 | 10 mM | S1480 | HCV Protease | VX-222 (VCH-222) is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase that is being investigated for the treatment of hepatitis C virus infection.
BMS-790052 | b7-L1700-04 | 1214735-16-6, 1009119-64-5 | 10 mM | [NAME] | HCV Protease | BMS-790052 is a first-in-class, highly-selective oral HCV NS5A inhibitor.
Iloperidone (Fanapt) | b8-L1700-04 | 133454-47-4, 1299470-39-5 (HCl) | 10 mM | S1483 |  | Iloperidone (Fanapt, Fanapta, Zomaril) is an atypical antipsychotic for the treatment of schizophrenia.
MC1568 | b9-L1700-04 | 852475-26-4, 1003600-29-0 | 10 mM | S1484 | HDAC | MC1568 is a potent selective class II (IIa) histone deacetylas (HDAC II) inhibitor (IC50 of a maize deacetylase HD2 at 22.0 µM).
HMN-214 | b10-L1700-04 | 173529-46-9 | 10 mM | S1485 | PLK | HMN-214 (a prodrug of HMN-176) is a potent PLK1 inhibitor (an average cell IC50 of 118nM).
AEE788 (NVP-AEE788) | b11-L1700-04 | 497839-62-0 | 10 mM | S1486 | EGFR, [NAME], VEGFR, [NAME] | AEE788 is a novel multitargeted human epidermal receptor (HER) 1/2 and vascular endothelial growth factor receptor (VEGFR) 1/2 receptor family tyrosine kinases inhibitor with IC50 of 2, 6, 77, 59 nM for EGFR, ErbB2, KDR, and Flt-1.
PHA-793887 | c1-L1700-04 | 718630-59-2, 718630-60-5 (HCl) | 10 mM | S1487 | CDK | PHA-793887 is a novel pan-cdk inhibitor, including [NAME], [NAME], cdk4, cdk5, cdk7, and cdk9 with IC50 in the 5 to 140 nM range.
PIK-93 | c2-L1700-04 | 593960-11-3 | 10 mM | S1489 | PI3K, VEGFR | PIK-93 is a PI4KIIIβinhibitor (IC50 at 19 nM).
Ponatinib (AP24534) | c3-L1700-04 | 943319-70-8, 1232836-25-7 (3HCl) | 10 mM | S1490 | Bcr-Abl, VEGFR, FGFR, PDGFR, Flt | AP24534 is a novel potent, orally available small molecule multitargeted kinase inhibitor with IC50 of 0.37, 2, 1.5, 2.2, 1.1, 1and 0.24 nM for native pan-BCR-ABL, mutated form, VEGFR2, FGFR1, PDGFRα, mutant FLT3 phosphorylation and LYN.
[NAME] (Fludara) | c4-L1700-04 | 21679-14-1 | 10 mM | S1491 | STAT, DNA/RNA Synthesis | [NAME] (Fludara) is a purine analog and a chemotherapy drug with IC50 < 3 [NAME]
LY2228820 | c5-L1700-04 | 862507-23-1, 862505-00-8 (free base), 862507-29-7 (HCl) | 10 mM | S1494 | p38 MAPK | LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38αMAPK and p38βMAPK were 7 nM and 3 nM, respectively).
NVP-BEP800 | c6-L1700-04 | 847559-80-2 | 10 mM | S1498 | HSP | NVP-BEP800 is a novel, fully synthetic, oral Hsp90 inhibitor with an IC50 of 0.058 ± 0.006 μM.
Mycophenolate mofetil (CellCept) | c7-L1700-04 | 128794-94-5, 116680-01-4 (HCl) | 10 mM | S1501 | Dehydrogenase | Mycophenolate mofetil is a inhibitor of inosine monophosphate dehydrogenase and a immunosuppressant.
Dyphylline (Dilor) | c8-L1700-04 | 479-18-5, 52756-53-3, 68350-70-9 | 10 mM | S1504 | PDE | Dyphylline ([NAME], Lufyllin, diprophylline) is a xanthine derivative with bronchodilator and vasodilator effects.
Aztreonam (Azactam, Cayston) | c9-L1700-04 | 78110-38-0 | 10 mM | S1505 |  | Aztreonam (Azactam, [NAME]) is a synthetic monocyclic beta-lactam antibiotic.
Perindopril Erbumine (Aceon) | c10-L1700-04 | 107133-36-8, 82834-16-0 (free base) | 10 mM | S1506 | RAAS | Perindopril [NAME]) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor.
[NAME] (Avapro) | c11-L1700-04 | 138402-11-6 | 10 mM | S1507 | RAAS | [NAME] (Avapro) belongs to the class of medicines called angiotensin II inhibitor antihypertensives.
Norfloxacin (Norxacin) | d1-L1700-04 | 70458-96-7, 68077-27-0 (HCl) | 10 mM | S1509 |  | Norfloxacin (Norxacin) is a broad-spectrum antibiotic.
[NAME] (Cialis) | d2-L1700-04 | 171596-29-5, 240822-07-5, 282541-36-0 | 10 mM | S1512 | PDE | [NAME] ([NAME]) is a PDE inhibitor.
SB939 (Pracinostat) | d3-L1700-04 | 929016-96-6, 929016-98-8 (2HCl), 929016-97-7 (TFA) | 10 mM | S1515 | HDAC | SB939 is a novel potent and orally active histone deacetylase inhibitor with an IC50 of 52 nM for HDAC1 and a GI50 of 0.56 μM for Colo205
Natamycin (Pimaricin) | d4-L1700-04 | 7681-93-8, 52882-37-8 | 10 mM | S1517 |  | Natamycin (Pimaricin) is a naturally occurring antifungal agent.
[NAME] (NeoProfen) | d5-L1700-04 | 57469-77-9, 82240-06-0, 127701-63-7,15687-27-1 (free base) | 10 mM | S1518 | COX | [NAME] (Motrin) is a non-steroidal anti-inflammatory drug.
CCT129202 | d6-L1700-04 | 942947-93-5 | 10 mM | S1519 | [NAME] | CCT129202 is a [NAME] kinase inhibitor with IC50 of 0.042 ± 0.022, 0.198 ± 0.05, and 0.227 ± 0.064 μmol/L for Aurora A, [NAME], and [NAME], respectively.
Tosedostat (CHR2797) | d7-L1700-04 | 238750-77-1 | 10 mM | S1522 | Aminopeptidase | Tosedostat (formerly CHR-2797) is an aminopeptidase inhibitor with IC50 of 100, 150, 220, >1000, >5000, >10000 and >30000 nM for LAP, PuSA, aminopeptidase N, aminopeptidase B, [NAME], [NAME] hydrolase and MetAP2, respectively.
XL765 | d8-L1700-04 | 1349796-36-6, 1123889-87-1 | 10 mM | S1523 | PI3K, mTOR | XL765 (SAR245409) is a mixed mTOR/PI3k inhibitor with IC50 of 157, 39, 113, 9 and 43 nM for mTOR, p110α, β, γ and δ, respectively.
AT7519 | d9-L1700-04 | 844442-38-2, 902135-91-5 (HCl), 902135-89-1 (methanesulfonate) | 10 mM | S1524 | CDK | AT7519 is a kinase inhibitor with IC50 of 0.19, 0.044, 0.51, 0.067, 0.66 and 0.018 μM for [NAME]/cyclinB, CDK2/CyclinA, CDK2/Cyclin E, CDk4/CyclinD1, [NAME]/[NAME], CDk5/p35.
Quizartinib (AC220) | d10-L1700-04 | 950769-58-1,1132827-21-4 (2HCl), 1132827-24-7 (methanesulfonate) | 10 mM | S1526 | Flt | [NAME] is a uniquely potent and selective FLT3 inhibitor with IC50 of 0.56 ± 0.3 nM and >10 mM for MC4-11 and A375, respectively.
Brivanib (BMS-540215) | d11-L1700-04 | 649735-46-6 | 10 mM | S1084 | VEGFR | Brivanib is an ATP-competitive inhibitor against human VEGFR2 and FGFR with IC50 of 25 nM and 148 nM, respectively.
Hesperadin | e1-L1700-04 | 422513-13-1 | 10 mM | S1529 | [NAME] | Hesperadin is a human [NAME] inhibitor with an IC50 of 40 nM for the prevention of the phosphorylation of substrate.
BIX 02188 | e2-L1700-04 | 1094614-84-2 | 10 mM | S1530 | MEK | BIX02188 is a MEK5-selective inhibitor with an IC50 of 0.8 ± 1.0 [NAME]
BIX 02189 | e3-L1700-04 | 1094614-85-3 | 10 mM | S1531 | MEK | BIX 02189 is a selective MEK5/ERK5 inhibitor with an IC50 of 59 nM.
AZD7762 | e4-L1700-04 | 860352-01-8, 1246094-78-9 (HCl), 1192875-06-1 (Fumaric acid) | 10 mM | S1532 | Chk | AZD7762 is a novel checkpoint kinase inhibitor with an IC50 of 5 and <10 nM for CHK1 and CHK2, respectively.
R406 (free base) | e5-L1700-04 | 841290-80-0 | 10 mM | S1533 | Syk | R406 (free base) is an orally available spleen tyrosine kinase inhibitor with a Ki of 30 nM.
PCI-24781 | e6-L1700-04 | 783355-60-2, 783356-67-2 (HCl) | 10 mM | S1090 | HDAC | PCI-24781 (CRA-024781) is a novel broad spectrum HDAC inhibitor targeting HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with [NAME] of 7 nM, 19 nM, 8.2 nM, 17 nM, 280 nM, 24 nM, respectively.
EX 527 | e7-L1700-04 | 49843-98-3 | 10 mM | S1541 | Sirtuin | EX 527 is a potent and selective SIRT1 class III histone deacetylase enzyme inhibitor with an IC50 of 38 nM.
MK3207 HCl | e8-L1700-04 | 957116-20-0, 957118-49-9 (free base) | 10 mM | S1542 | CGRP Receptor | MK3207 hydrochloride is a potent and orally active calcitonin gene-related peptide receptor antagonist. (Ki = 0.024 nM)
Febuxostat (Uloric) | e9-L1700-04 | 144060-53-7, 1140907-13-6 (sodium salt) | 10 mM | S1547 |  | Febuxostat is a non-purine selective xanthine oxidase inhibitor with IC50 of 114 -210 nM.
Nebivolol (Bystolic) | e10-L1700-04 | 152520-56-4, 118457-14-0 (free base) | 10 mM | S1549 | Adrenergic Receptor | Nebivolol (Bystolic) is a β1 receptor blocker with an IC50 of 4.5 µM.
[NAME] (Vetmedin) | e11-L1700-04 | 74150-27-9, 77469-98-8 (HCl) | 10 mM | S1550 | PDE | [NAME] (Vetmedin) is a Ca(2+) sensitizer with an IC50 of 26 µM and a selective phosphodiesterase III inhibitor with an IC50 of <1 µM.
AZD8055 | f1-L1700-04 | 1009298-09-2, 1201799-04-3 (D(-)-Tartaric Acid), 1201799-05-4 (Fumaric acid) | 10 mM | S1555 | mTOR | AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.
Linsitinib (OSI-906) | f2-L1700-04 | 867160-71-2 | 10 mM | S1091 | IGF-1R | OSI-906 (Linsitinib) is a selective inhibitor of IGF-IR and IR with IC50 of 35 nM and 75 nM, respectively.
KRN 633 | f3-L1700-04 | 286370-15-8 | 10 mM | S1557 | VEGFR, PDGFR | KRN 633 is a cell-permeable, reversible, ATP-competitive VEGFR kinase inhibitor with IC50 of 170 nM, 160 nM, and 125 nM for VEGFR-1, VEGFR-2, VEGFR-3, respectively.
AT7867 | f4-L1700-04 | 857531-00-1 | 10 mM | S1558 | [NAME], S6 kinase | AT7867 is a potent and oral AKT and p70 S6 kinase inhibitor with an IC50 of 17 nM.
BMS 777607 | f5-L1700-04 | 1196681-44-3, 1025720-94-8 | 10 mM | S1561 | c-Met | BMS 777607 is a Small-Molecule Met Kinase Inhibitor with an IC50 of < 0.1 μM.
Pomalidomide | f6-L1700-04 | 19171-19-8, 443912-23-0, 443919-33-3 | 10 mM | S1567 | TNF-alpha, COX | Pomalidomide is tumor necrosis factor-α inhibitor and a new immunomodulator with an IC50 of 1 μM.
PD318088 | f7-L1700-04 | 391210-00-7 | 10 mM | S1568 | MEK | PD318088 is a non-ATP competitive allosteric MEK1/2 inhibitor.
Tazarotene (Avage) | f8-L1700-04 | 118292-40-3 | 10 mM | S1569 |  | Tazarotene is a prescription topical retinoid sold as a cream or gel.
[NAME] | f9-L1700-04 | 925701-49-1 | 10 mM | S1570 | ATM | [NAME] is a specific improved ATM kinase inhibitor.
BS-181 HCl | f10-L1700-04 | 1092443-52-1 (free base) | 10 mM | S1572 | CDK | BS-181 is a selective cyclin-dependent kinase inhibitor with an IC50 of 21 nM for the inhibition of CDK-activating kinase.
Fasudil HCl (HA-1077) | f11-L1700-04 | 105628-07-7,103745-39-7 (free base) | 10 mM | S1573 | ROCK | Fasudil HCl is cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor with an IC50 of 10.7 μM.
BIRB 796 (Doramapimod) | g1-L1700-04 | 285983-48-4, 1283526-53-3 (HCl) | 10 mM | S1574 | p38 MAPK | BIRB796 Doramapimod a small molecule of p38 MAPK inhibitor with Kd of 0.1 nM is available at Selleck.
RO4929097 | g2-L1700-04 | 847925-91-1 | 10 mM | S1575 | [NAME] | RO4929097 is an orally bioavailable, small-molecule gamma secretase (GS) inhibitor with an IC50 of 4 nM.
Apixaban | g3-L1700-04 | 503612-47-3, 898235-61-5 (H2O) | 10 mM | S1593 | Factor Xa | Apixaban is a direct factor [NAME] inhibitor with an IC50 of 0.22±0.02 µM.
Semagacestat (LY450139) | g4-L1700-04 | 425386-60-3, 866488-53-1 | 10 mM | S1594 | Gamma-secretase | Semagacestat (LY450139) is a γ-secretase blocker with an IC50 of 15 nM.
LY500307 (Erteberel) | g5-L1700-04 | 533884-09-2 | 10 mM | S1598 | Estrogen/progestogen Receptor | LY500307 is a potent, selective estrogen receptor β agonist with an EC50 of 0.66 nM.
Reserpine | g6-L1700-04 | 50-55-5, 1407-38-1, 8048-25-7, 16994-56-2 (HCl) | 10 mM | S1601 |  | Reserpine is an indole alkaloid antipsychotic and antihypertensive drug that has been used for the control of high blood pressure and for the relief of psychotic symptoms.
Furosemide (Lasix) | g7-L1700-04 | 54-31-9, 41733-55-5 (sodium salt) | 10 mM | S1603 |  | Furosemide (Lasix) is a loop diuretic used in the treatment of congestive heart failure and edema.
Cefdinir ([NAME]) | g8-L1700-04 | 91832-40-5 | 10 mM | S1605 |  | Cefdinir ([NAME]) is a bacteriocidal antibiotic.
Clotrimazole (Canesten) | g9-L1700-04 | 23593-75-1 | 10 mM | S1606 |  | Clotrimazole (Canesten) is a synthetic, antifungal and broad-spectrum derivate of imidazole.
Rizatriptan Benzoate (Maxalt) | g10-L1700-04 | 145202-66-0 | 10 mM | S1607 | 5-HT Receptor | Rizatriptan Benzoate (Maxalt) is a 5-HT1 agonist triptan drug for the treatment of migraine headaches.
[NAME] (Mestinon) | g11-L1700-04 | 101-26-8, 155-97-5 (FREE BASE) | 10 mM | S1608 | AChR | [NAME] ([NAME]) is a parasympathomimetic and a reversible cholinesterase inhibitor.
Methimazole (Tapazole, [NAME]) | h1-L1700-04 | 60-56-0 | 10 mM | S1609 |  | Methimazole (Tapazole, [NAME]) is an antithyroid medicine.
[NAME] ([NAME]) | h2-L1700-04 | 17560-51-9 | 10 mM | S1610 |  | [NAME] ([NAME]) is primarily used to treat congestive heart failure and high blood pressure.
Riluzole (Rilutek) | h3-L1700-04 | 1744-22-5 | 10 mM | S1614 | Sodium Channel | Riluzole (Rilutek) is a drug used to treat amyotrophic lateral sclerosis.
Risperidone (Risperdal) | h4-L1700-04 | 106266-06-2, 666179-74-4 (HCl), 666179-96-0 (methanesulfonate) | 10 mM | S1615 | 5-HT Receptor | Risperidone (Risperdal) is an atypical antipsychotic used to treat schizophrenia.
Sulfameter (Bayrena) | h5-L1700-04 | 651-06-9 | 10 mM | S1618 |  | Sulfameter (Bayrena) is a long-acting sulfonamide antibacterial.
Prilocaine | h6-L1700-04 | 721-50-6, 1786-81-8 (HCl) | 10 mM | S1619 |  | Prilocaine is a local anesthetic of the amino amide type.
GSK1904529A | h7-L1700-04 | 1089283-49-7 | 10 mM | S1093 | IGF-1R | GSK1904529A is a selective inhibitor of IGF-IR and IR with IC50 of 27 nM and 25 nM, respectively.
Prednisone (Adasone) | h8-L1700-04 | 53-03-2 | 10 mM | S1622 |  | Prednisone (Adasone) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant drug.
Acetylcysteine | h9-L1700-04 | 616-91-1 | 10 mM | S1623 | AChR | Acetylcysteine is a pharmaceutical drug and nutritional supplement used primarily as a mucolytic agent and in the management of paracetamol (acetaminophen) overdose.
Alendronate (Fosamax) | h10-L1700-04 | 121268-17-5 | 10 mM | S1624 |  | Alendronate Sodium (Fosamax) is a farnesyl diphosphate synthase inhibitor with IC50 of 460 nM.
[NAME] | h11-L1700-04 | 57-63-6 | 10 mM | S1625 |  | Ethynyl estradiol is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills.
Nitazoxanide (Alinia, Annita) | a1-L1700-05 | 55981-09-4 | 10 mM | S1627 |  | Nitazoxanide (Alinia, Annita) is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM)
Triamcinolone Acetonide | a2-L1700-05 | 76-25-5 | 10 mM | S1628 |  | Triamcinolone Acetonide is a more potent type of triamcinolone, being about 8 times as effective as prednisone.
Orlistat (Alli, [NAME]) | a3-L1700-05 | 96829-58-2 | 10 mM | S1629 |  | Orlistat is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice.
[NAME] (Zyloprim) | a4-L1700-05 | 315-30-0 | 10 mM | S1630 | OX Receptor | [NAME] (Zyloprim) is a clinically used xanthine oxidase (XO) inhibitor ,and its IC50 value is 0.78μM.
Allopurinol Sodium (Aloprim) | a5-L1700-05 | 17795-21-0 | 10 mM | S1631 |  | Allopurinol Sodium (Aloprim) is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 µM.
BTZ043 racemate | a6-L1700-05 | 957217-65-1 | 10 mM | S1097 |  | BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.
Erythromycin (E-Mycin) | a7-L1700-05 | 114-07-8 | 10 mM | S1635 |  | Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).
Ibuprofen (Advil) | a8-L1700-05 | 15687-27-1 | 10 mM | [NAME] | COX | Ibuprofen is a non-selective COX inhibitor with an IC50 of 3.3 x 10-4 M.
Albendazole (Albenza) | a9-L1700-05 | 54965-21-8 | 10 mM | S1640 |  | Albendazole (Albenza) is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations.
Chlorothiazide | a10-L1700-05 | 58-94-6 | 10 mM | [NAME] |  | Chlorothiazide is a diuretic and antihypertensive. ([NAME])
Ursodiol (Actigal [NAME]) | a11-L1700-05 | 128-13-2 | 10 mM | S1643 |  | Ursodiol reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones. (IC50=0.22 µM)
Nitrofurazone (Nitrofural) | b1-L1700-05 | 59-87-0 | 10 mM | S1644 |  | Nitrofurazone is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 µM. (Rat LD50 = 590 mg/kg)
Ketoprofen (Actron) | b2-L1700-05 | 22071-15-4 | 10 mM | S1645 | COX | Ketoprofen is a non-selective NSAID with IC50 of 0.5 μM and 2.33 μM for human recombinant COX-1 and COX-2, respectively.
Ketorolac ([NAME]) | b3-L1700-05 | 74103-07-4 | 10 mM | S1646 | COX | Ketorolac tromethamine is a non-selective COX inhibitor with IC50 of 31.5 µM and 60.5 µM for human recombinant COX-1 and COX-2, respectively.
Adenosine (Adenocard) | b4-L1700-05 | 58-61-7, 58056-57-8 (xHCl) | 10 mM | S1647 |  | Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a β-N9-glycosidic bond.
Cytarabine | [NAME] | 147-94-4, 69-74-9 (HCl) | 10 mM | S1648 | DNA/RNA Synthesis | Cytarabine (Cytosar-U) is an antimetabolic agent and a DNA polymerase with an IC50 of 16 nM for wild-type CCRF-CEM cells.
Zolmitriptan (Zomig) | b6-L1700-05 | 139264-17-8 | 10 mM | S1649 |  | Zolmitriptan (Zomig) is a selective serotonin receptor agonist.
Telbivudine (Sebivo, [NAME]) | b7-L1700-05 | 3424-98-4 | 10 mM | S1651 |  | [NAME] (Tyzeka, Sebivo) is an antiviral drug used in the treatment of hepatitis B infection.
Monobenzone (Benoquin) | b8-L1700-05 | 103-16-2 | 10 mM | S1652 |  | Monobenzone (Benoquin) is a compound used as a topical drug for medical depigmentation.
Tretinoin ([NAME]) | b9-L1700-05 | 302-79-4 | 10 mM | S1653 |  | Tretinoin ([NAME]) is a drug commonly used to treat acne vulgaris and keratosis pilaris.
Phenylbutazone (Butazolidin, Butatron) | b10-L1700-05 | 50-33-9 | 10 mM | S1654 |  | Phenylbutazone (Butazolidin, Butatron) is used as a non-steroidal anti-inflammatory drug for the treatment of chronic pain, including the symptoms of arthritis.
Ezetimibe (Zetia) | b11-L1700-05 | 163222-33-1 | 10 mM | S1655 |  | Ezetimibe (Zetia) is a drug that lowers cholesterol.
Enalaprilat dihydrate | c1-L1700-05 | 84680-54-6 | 10 mM | S1657 | RAAS | [NAME] is the first dicarboxylate-containing ACE inhibitor with an IC50 of 4 nM.
Estrone | c2-L1700-05 | 53-16-7 | 10 mM | S1665 |  | Estrone is an estrogenic hormone.
Flucytosine (Ancobon) | c3-L1700-05 | 2022-85-7 | 10 mM | S1666 |  | Flucytosine (Ancobon) is a fluorinated pyrimidine analogue and a synthetic antimycotic drug.
Loteprednol etabonate | c4-L1700-05 | 82034-46-6 | 10 mM | S1669 |  | [NAME] etabonate is an anti-inflammatory corticosteroid used in ophthalmology
Aminocaproic acid (Amicar) | c5-L1700-05 | 60-32-2 | 10 mM | S1671 |  | Aminocaproic acid (Amicar) is a derivative and analogue of the amino acid lysine.
Aminophylline (Truphylline) | c6-L1700-05 | 317-34-0 | 10 mM | S1673 | PDE | Aminophylline (Phyllocontin, Truphylline) is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist.
Amorolfine Hydrochloride | c7-L1700-05 | 78613-38-4 | 10 mM | S1676 |  | Amorolfine hydrochloride is a antifungal reagent.
Chloramphenicol (Chloromycetin) | c8-L1700-05 | 56-75-7 | 10 mM | S1677 |  | Chloramphenicol (Chloromycetin) is a bacteriostatic antimicrobial.
MLN8054 | c9-L1700-05 | 869363-13-3, 869366-15-4 (sodium salt) | 10 mM | S1100 | [NAME] | [NAME] is a potent and selective inhibitor of [NAME] with IC50 of 4 nM.
[NAME] (Ansaid) | c10-L1700-05 | 5104-49-4 | 10 mM | S1679 |  | [NAME] is a member of the phenylalkanoic acid derivative family of non-steroidal anti-inflammatory drugs (NSAIDs).
Disulfiram (Antabuse) | c11-L1700-05 | 97-77-8 | 10 mM | S1680 |  | Disulfiram (Antabuse) is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.
Mesalamine ([NAME]) | d1-L1700-05 | 89-57-6 | 10 mM | S1681 |  | Mesalamine ([NAME], Apriso) is an anti-inflammatory drug.
Ipratropium bromide | d2-L1700-05 | 22254-24-6 | 10 mM | S1683 |  | Ipratropium bromide is a muscarinic antagonist, bronchodilator, N-Isopropyl salt of atropine.
Sulfanilamide | d3-L1700-05 | 63-74-1 | 10 mM | S1685 |  | Sulfanilamide is a sulfonamide antibacterial.
Betamethasone Dipropionate (Diprolene) | d4-L1700-05 | 5593-20-4 | 10 mM | S1688 |  | Betamethasone Dipropionate (Diprolene) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.
[NAME] (Meprednisone) | d5-L1700-05 | 1247-42-3 | 10 mM | S1689 |  | [NAME] (Meprednisone) is a glucocorticoid and a methylated derivative of prednisone.
Betamethasone valerate (Betnovate) | d6-L1700-05 | 2152-44-5 | 10 mM | S1690 |  | Betamethasone valerate (Betnovate, Celestone) is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.
Busulfan ([NAME], Busulfex) | d7-L1700-05 | 55-98-1 | 10 mM | S1692 |  | Busulfan ([NAME], Busulfex) is a cell cycle non-specific alkylating antineoplastic agent.
[NAME] (Carbatrol) | d8-L1700-05 | 298-46-4 | 10 mM | S1693 |  | [NAME] is a sodium channel blocker with an IC50 of 140 µM.
Hydrocortisone (Cortisol) | d9-L1700-05 | 50-23-7 | 10 mM | S1696 |  | Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland.
Torsemide (Demadex) | d10-L1700-05 | 56211-40-6 | 10 mM | S1698 |  | Torsemide (Demadex) is a pyridine-sulfonyl urea type loop diuretic with an IC50 of 2.7 ± 0.17 µM.
OSU-03012 | d11-L1700-05 | 742112-33-0 | 10 mM | S1106 | PDK-1 | OSU-03012 is a potent inhibitor of recombinant [NAME] with IC50 of 5 ¦ÌM
Desonide | e1-L1700-05 | 638-94-8 | 10 mM | S1701 |  | Desonide is a low potency topical corticosteroid.
Didanosine (Videx) | e2-L1700-05 | 69655-05-6 | 10 mM | S1702 |  | Didanosine (Videx, Videx EC) is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.
Divalproex sodium | e3-L1700-05 | 76584-70-8 | 10 mM | S1703 |  | Divalproex sodium consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form.
Emtricitabine (Emtriva) | e4-L1700-05 | 143491-57-0 | 10 mM | S1704 | NART | Emtricitabine ([NAME]) is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM.
Progesterone (Prometrium) | e5-L1700-05 | 57-83-0 | 10 mM | S1705 |  | Progesterone (Prometrium) is a C-21 steroid hormone.
Lamivudine (Epivir) | e6-L1700-05 | 134678-17-4 | 10 mM | S1706 |  | Lamivudine (Epivir) is a potent nucleoside analog reverse transcriptase inhibitor with an IC50 of 2.7 [NAME]
Eplerenone | e7-L1700-05 | 107724-20-9 | 10 mM | S1707 |  | Eplerenone (Inspra) is an aldosterone antagonist with an IC50 of 0.36 [NAME]
Hydrochlorothiazide | e8-L1700-05 | 58-93-5 | 10 mM | S1708 |  | Hydrochlorothiazide is a first line diuretic drug of the thiazide class.
[NAME] | e9-L1700-05 | 50-28-2 | 10 mM | S1709 |  | [NAME] is the predominant sex hormone.
Piroxicam (Feldene) | e10-L1700-05 | 36322-90-4 | 10 mM | S1713 | COX | Piroxicam (Feldene, Roxam) is a non-selective COX inhibitor with an IC50 of 6 [NAME]
Glipizide (Glucotrol) | e11-L1700-05 | 29094-61-9 | 10 mM | S1715 |  | Glipizide (Glucotrol) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.
Glyburide (Diabeta) | f1-L1700-05 | 10238-21-8 | 10 mM | S1716 |  | Glyburide ([NAME]) is an anti-diabetic drug in a class of medications known as sulfonylureas, closely related to sulfa drugs.
[NAME] (Preveon, Hepsera) | f2-L1700-05 | 142340-99-6 | 10 mM | S1718 |  | [NAME] (Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body.
Zalcitabine | f3-L1700-05 | 7481-89-2 | 10 mM | S1719 |  | Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).
Indomethacin (Indocid, Indocin) | f4-L1700-05 | 53-86-1 | 10 mM | S1723 |  | Indomethacin (Indocid, Indocin) is a non-steroidal anti-inflammatory drug commonly used to reduce fever, pain, stiffness, and swelling.
Paliperidone (Invega) | f5-L1700-05 | 144598-75-4 | 10 mM | S1724 |  | Paliperidone (Invega) is an atypical antipsychotic.
Terbinafine (Lamisil, Terbinex) | f6-L1700-05 | 91161-71-6 | 10 mM | S1725 |  | Terbinafine (Lamisil, Terbinex) is used to treat infections caused by a fungus. It works by killing the fungus or preventing its growth.
Levodopa (Sinemet) | f7-L1700-05 | 59-92-7 | 10 mM | S1726 |  | Levodopa (Sinemet) is an amino acid precursor of dopamine with antiparkinsonian properties.
Levonorgestrel (Levonelle) | f8-L1700-05 | 797-63-7 | 10 mM | S1727 |  | Levonorgestrel ([NAME]) is a synthetic progestogen used as an active ingredient in some hormonal contraceptives.
Gemfibrozil (Lopid) | f9-L1700-05 | 25812-30-0 | 10 mM | S1729 |  | Gemfibrozil (Lopid) is an oral drug used to lower lipid levels.
Indapamide (Lozol) | f10-L1700-05 | 26807-65-8 | 10 mM | S1730 |  | Indapamide (Lozol) is a non-thiazide sulphonamide diuretic drug, generally used in the treatment of hypertension, as well as decompensated cardiac failure.
Methylprednisolone | f11-L1700-05 | 83-43-2 | 10 mM | S1733 |  | Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties.
Mesna (Uromitexan, Mesnex) | g1-L1700-05 | 19767-45-4 | 10 mM | S1735 |  | Mesna (Uromitexan, Mesnex), a sulfhydryl compound that is used to reduce the incidence of hemorrhagic cystitis associated with certain chemotherapeutic agents.
[NAME] ([NAME]) | g2-L1700-05 | 532-03-6 | 10 mM | S1736 |  | [NAME] ([NAME]) is a central muscle relaxant used to treat skeletal muscle spasms.
Prednisolone (Hydroretrocortine) | g3-L1700-05 | 50-24-8 | 10 mM | S1737 |  | Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
Telmisartan (Micardis) | g4-L1700-05 | 144701-48-4 | 10 mM | S1738 |  | Telmisartan ([NAME]) is an angiotensin II receptor antagonist (ARB) used in the management of hypertension.
Guaifenesin (Guaiphenesin) | g5-L1700-05 | 93-14-1 | 10 mM | S1740 |  | Guaifenesin (Guaiphenesin) is thought to act as an expectorant.
Rifabutin (Mycobutin) | g6-L1700-05 | 72559-06-9 | 10 mM | S1741 |  | Rifabutin (Mycobutin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties.
Nevirapine (Viramune) | g7-L1700-05 | 129618-40-2 | 10 mM | S1742 |  | Nevirapine (Viramune) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.
Niacin (Nicotinic acid) | g8-L1700-05 | 59-67-6 | 10 mM | S1744 |  | Niacin (Nicotinic acid) is a water-soluble vitamin belonging to the vitamin B family.
Nimodipine (Nimotop) | g9-L1700-05 | 66085-59-4 | 10 mM | S1747 |  | Nimodipine (Nimotop) is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.
Nisoldipine (Sular) | g10-L1700-05 | 63675-72-9 | 10 mM | [NAME] |  | Nisoldipine (Sular) is a calcium channel blocker.
L-Glutamine | g11-L1700-05 | 56-85-9 | 10 mM | S1749 |  | L-Glutamine is one of the 20 amino acids encoded by the standard genetic code.
Gadodiamide (Omniscan) | h1-L1700-05 | 122795-43-1 | 10 mM | S1751 |  | Gadodiamide (Omniscan) is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels.
Varespladib (LY315920) | h2-L1700-05 | 172732-68-2, 172733-42-5 (sodium salt) | 10 mM | S1110 | Phospholipase (e.g. PLA) | LY315920 (Varespladib) is a potent and selective secretory phospholipase A2 (sPLA) inhibitor with IC50 of 7 nM.
Oxybutynin ([NAME]) | h3-L1700-05 | 5633-20-5 | 10 mM | S1754 |  | Oxybutynin ([NAME]) is an anticholinergic medication used to relieve urinary and bladder difficulties.
[NAME] calcium ([NAME]) | h4-L1700-05 | 147526-32-7 | 10 mM | S1759 |  | [NAME] calcium ([NAME]) is a novel member of the medication class of statins.
Rifapentine (Priftin) | h5-L1700-05 | 61379-65-5 | 10 mM | S1760 |  | Rifapentine (Priftin) is an antibiotic drug used in the treatment of tuberculosis.
Pyrazinamide (Pyrazinoic acid amide) | h6-L1700-05 | 98-96-4 | 10 mM | S1762 |  | Pyrazinamide (Pyrazinoic acid amide) is a drug used to treat tuberculosis.
Quetiapine fumarate (Seroquel) | h7-L1700-05 | 111974-72-2 | 10 mM | S1763 | Dopamine Receptor | Quetiapine fumarate(Seroquel) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression.
Cefditoren pivoxil | h8-L1700-05 | 117467-28-4 | 10 mM | S1768 | 5-alpha Reductase | Cefditoren pivoxil is used to treat uncomplicated skin and skin structure infections, etc.
Sulfadiazine | h9-L1700-05 | 68-35-9 | 10 mM | S1770 |  | Sulfadiazine is a sulfonamide antibiotic.
[NAME] | h10-L1700-05 | 113-59-7 | 10 mM | S1771 |  | [NAME] is a typical antipsychotic drug of the thioxanthene class and was the first of the series to be synthesized.
Oxytetracycline (Terramycin) | h11-L1700-05 | 79-57-2 | 10 mM | S1773 |  | Oxytetracycline (Terramycin) was the second of the broad-spectrum tetracycline group of antibiotics to be discovered.
Thioguanine | a1-L1700-06 | 154-42-7 | 10 mM | S1774 |  | The thiopurine drugs are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients.
[NAME] (Fareston, Acapodene) | a2-L1700-06 | 89778-27-8 | 10 mM | S1776 |  | [NAME] (Fareston, [NAME]) is an oral selective estrogen receptor modulator (SERM) which helps oppose the actions of estrogen in the body.
Ethionamide | a3-L1700-06 | 536-33-4 | 10 mM | S1777 |  | Ethionamide (2-ethylthioisonicotinamide) is an antibiotic used in the treatment of tuberculosis.
Trifluridine (Viroptic) | a4-L1700-06 | 70-00-8 | 10 mM | S1778 |  | Trifluridine (Viroptic) is an anti-herpesvirus antiviral drug, used primarily on the eye.
Vidarabine (Vira-A) | a5-L1700-06 | 5536-17-4 | 10 mM | S1784 | 5-alpha Reductase | Vidarabine (Vira-A) is an antiviral drug which is active against herpes simplex and [NAME] viruses.
Teniposide (Vumon) | a6-L1700-06 | 29767-20-2 | 10 mM | S1787 |  | Teniposide (Vumon)is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).
GSK690693 | a7-L1700-06 | 937174-76-0 | 10 mM | S1113 | [NAME] | GSK690693 is a pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 2 nM, 13 nM, and 9 nM, respectively.
Rifaximin ([NAME]) | a8-L1700-06 | 80621-81-4 | 10 mM | S1790 |  | Rifaximin ([NAME]), an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity.
Simvastatin (Zocor) | a9-L1700-06 | 79902-63-9 | 10 mM | S1792 |  | Simvastatin(Zocor) is a hypolipidemic drug belonging to the class of pharmaceuticals called "statins".
Ramipril (Altace) | a10-L1700-06 | 87333-19-5 | 10 mM | S1793 | RAAS | Ramipril (Altace) is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 5 nM.
Fenofibrate (Tricor, Trilipix) | a11-L1700-06 | 49562-28-9 | 10 mM | S1794 |  | Fenofibrate (Tricor, [NAME]) is a drug of the fibrate class and fibric acid derivative
Ranolazine (Ranexa) | b1-L1700-06 | 95635-55-5 | 10 mM | S1799 |  | Ranolazine (Ranexa) is an antianginal medication.
Ranitidine (Zantac) | b2-L1700-06 | 66357-59-3 | 10 mM | S1801 |  | Ranitidine hydrochloride (Zantac) is a histamine H2-receptor antagonist with IC50 of 3.3 ± 1.4 µM.
Acadesine | b3-L1700-06 | 2627-69-2, 681006-28-0 (xH3O4P) | 10 mM | S1802 | AMPK | Acadesine is an AMP-activated protein kinase activator which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes.
Acipimox | b4-L1700-06 | 51037-30-0, 76958-97-9 (sodium salt) | 10 mM | S1806 |  | Acipimox is a niacin derivative used as a hypolipidemic agent.
Acyclovir (Aciclovir) | [NAME] | 59277-89-3 | 10 mM | S1807 | Others | Acyclovir is a synthetic nucleoside analogue active against herpesviruses
Amiloride hydrochloride (Midamor) | b6-L1700-06 | 2016-88-8, 2609-46-3(free base) | 10 mM | S1811 |  | Amiloride hydrochloride (Midamor), a pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells.
Amlodipine besylate (Norvasc) | b7-L1700-06 | 111470-99-6 | 10 mM | S1813 |  | Amlodipine besylate (Norvasc), a long-acting dihydropyridine calcium channel blocker, is effective in the treatment of angina pectoris and hypertension
Clofibrate (Atromid-S) | b8-L1700-06 | 637-07-0 | 10 mM | S1820 |  | Clofibrate (Atromid-S), a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia.
Chloroxine | b9-L1700-06 | 773-76-2 | 10 mM | S1839 |  | Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.
Lomustine (CeeNU) | b10-L1700-06 | 13010-47-4 | 10 mM | S1840 |  | Lomustine (CeeNU) is an alkylating agent of value against both hematologic malignancies and solid tumors.
Chenodeoxycholic acid | b11-L1700-06 | 474-25-9 | 10 mM | S1843 |  | Chenodeoxycholic acid is a naturally occurring human bile acid.
Cimetidine (Tagamet) | c1-L1700-06 | 51481-61-9, 76181-71-0, 270574-63-5 | 10 mM | S1845 |  | Cimetidine (Tagamet), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.
Clemastine Fumarate | c2-L1700-06 | 14976-57-9, 15686-51-8 (free base) | 10 mM | S1847 | Histamine Receptor | Clemastine fumarate, a histamine H1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus.
Daidzein | c3-L1700-06 | 486-66-8 | 10 mM | S1849 |  | Daidzein belongs to the group of isoflavones.
Diphenhydramine HCl (Benadryl) | c4-L1700-06 | 147-24-0 | 10 mM | S1866 |  | Diphenhydramine hydrochloride (Benadryl), a histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations.
Dapoxetine hydrochloride ([NAME]) | c5-L1700-06 | 129938-20-1 | 10 mM | S1869 | 5-HT Receptor | Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor.
Odanacatib (MK 0822) | c6-L1700-06 | 603139-19-1 | 10 mM | S1115 | Cathepsin K | Odanacatib (MK 0822) is a potent, selective, and neutral inhibitor of human and rabbit cathepsin K with IC50 of 0.2 nM and 1 nM , respectively.
Felodipine (Plendil) | c7-L1700-06 | 72509-76-3 | 10 mM | S1885 |  | Felodipine (Plendil, Renedil) is a calcium channel blocker with an IC50 of 3 µM and 2 x 10 µM for the formyl-Met-Leu-Phe-induced cytosolic calcium increase and H2O2 production, respectively.
Deflazacort (Calcort) | c8-L1700-06 | 14484-47-0, 74712-90-6 | 10 mM | S1888 |  | Deflazacort (Calcort) is a glucocorticoid used as an anti-inflammatory and immunosuppressant.
Nizatidine | c9-L1700-06 | 76963-41-2 | 10 mM | S1890 |  | Nizatidine (Axid) is a histamine H2-receptor antagonist with and IC50 of 6.7 nM for AChE.
Carbidopa | c10-L1700-06 | 28860-95-9 | 10 mM | S1891 |  | Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor with an IC50 of 29 ± 2 μM.
[NAME] (Diovan) | c11-L1700-06 | 137862-53-4 | 10 mM | S1894 | RAAS | [NAME] ([NAME]) is an angiotensin II receptor antagonist with IC50 of ranging from 39.5 to 116 µM.
Dipyridamole (Persantine) | d1-L1700-06 | 58-32-2, 763-39-4 (XHCl) | 10 mM | [NAME] |  | [NAME] (Permole, Persantine) is a phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells.
Hydroxyurea (Cytodrox) | d2-L1700-06 | 127-07-1 | 10 mM | S1896 |  | Hydroxyurea (Cytodrox) is an antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
Potassium iodide | d3-L1700-06 | 7681-11-0 | 10 mM | S1897 |  | Potassium iodide is used to treat overactive thyroid and to protect the thyroid gland from the effects of radiation from inhaled or swallowed radioactive iodine.
Tropisetron | d4-L1700-06 | 105826-92-4 | 10 mM | S1898 |  | Tropisetron hydrochloride is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
Nicotinamide (Niacinamide) | d5-L1700-06 | 98-92-0 | 10 mM | S1899 |  | Nicotinamide (Niacinamide) is a water-soluble vitamin and is part of the vitamin B group.
[NAME] | d6-L1700-06 | 68-19-9 | 10 mM | S1902 |  | Vitamin b12 is a water soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood.
Diclofenac | d7-L1700-06 | 15307-79-6 | 10 mM | S1903 | COX | Diclofenac is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively.
Fluvastatin sodium (Lescol) | d8-L1700-06 | 93957-55-2, 126872-01-3, 885513-60-0, 93957-54-1 (free base) | 10 mM | S1909 | HMG-CoA Reductase | Fluvastatin Sodium (Lescol) is an orally active, potent and competitive HMG-CoA reductase inhibitor with an IC50 of 70 nM for vascular smooth muscle proliferation in vitro.
Sulfamethoxazole | d9-L1700-06 | 723-46-6 | 10 mM | S1915 |  | [NAME] ([NAME]) is a sulfonamide bacteriostatic antibiotic with an IC50 of 2.7 [NAME]
Sulfisoxazole | d10-L1700-06 | 127-69-5 | 10 mM | S1916 |  | Sulfisoxazole is a sulfonamide antibacterial with an oxazole substituent.
Crystal violet | d11-L1700-06 | 548-62-9 | 10 mM | S1917 |  | Crystal violet is a triarylmethane dye.
[NAME] (Haldol) | e1-L1700-06 | 52-86-8 | 10 mM | S1920 |  | [NAME] (Haldol)) is an antipsychotic and butyrophenone.
Triamcinolone (Aristocort) | e2-L1700-06 | 124-94-7 | 10 mM | S1933 |  | Triamcinolone (Aristocort) is a glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated.
[NAME] ([NAME]) | e3-L1700-06 | 1400-61-9 | 10 mM | S1934 | PI3K, [NAME], mTOR | [NAME] ([NAME]) is a polyene antifungal drug to which many molds and yeasts are sensitive, including Candida spp.
Isoniazid (Tubizid) | e4-L1700-06 | 54-85-3 | 10 mM | S1937 | Angiogenesis | Isoniazid (Tubizid) is a prodrug and must be activated by bacterial catalase.
Levamisole Hydrochloride (Ergamisol) | e5-L1700-06 | 16595-80-5 | 10 mM | S1939 | Angiogenesis | Levamisole Hydrochloride (Ergamisol)is an antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function.
[NAME]) | e6-L1700-06 | 100986-85-4 | 10 mM | S1940 |  | [NAME]) is a synthetic fluoroquinolone (fluoroquinolones) antibacterial agent.
[NAME] maleate (Vasotec) | e7-L1700-06 | 76095-16-4 | 10 mM | S1941 | Opioid Receptor | [NAME] maleate (Vasotec ), the active metabolite of enalapril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II.
Metformin hydrochloride (Glucophage) | e8-L1700-06 | 1115-70-4 | 10 mM | S1950 |  | Metformin hydrochloride (Glucophage) is a biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification.
Methoxsalen (Oxsoralen) | e9-L1700-06 | 298-81-7, 12692-94-3 | 10 mM | S1952 |  | Methoxsalen (Oxsoralen) a naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia, is a drug used to treat psoriasis, eczema, vitiligo and some cutaneous [NAME] in conjunction with exposing the skin to sunlight.
Miconazole nitrate | e10-L1700-06 | 22832-87-7 | 10 mM | S1956 |  | Miconazole is an imidazole antifungal agent that is used topically and by intravenous infusion.
Primidone (Mysoline) | e11-L1700-06 | 125-33-7 | 10 mM | S1965 |  | Primidone (Mysoline) is an anticonvulsant of the pyrimidinedione class.
Nefiracetam (Translon) | f1-L1700-06 | 77191-36-7 | 10 mM | S1969 | GABA Receptor | Nefiracetam (Translon) is cognitive enhancer with an IC50 of approximately 150–200 μM for [NAME].
[NAME] (Ikorel) | f2-L1700-06 | 65141-46-0 | 10 mM | S1971 |  | [NAME] (Ikorel) is potassium channel activator.
Tamoxifen Citrate (Nolvadex) | f3-L1700-06 | 54965-24-1 | 10 mM | S1972 | Estrogen/progestogen Receptor | Tamoxifen (Nolvadex) is an estrogen receptor antagonist with an IC50 of 31 μM for the MCF-7 cells.
Capsaicin | f4-L1700-06 | 404-86-4 | 10 mM | S1990 |  | Capsaicin (Qutenza) is an active component of chili peppers, which are plants belonging to the genus Capsicum.
Sodium butyrate | f5-L1700-06 | 156-54-7, 107-92-6(free base) | 10 mM | S1999 |  | Sodium butyrate is a compound with formula Na (C3H7COO)
Sodium orthovanadate | f6-L1700-06 | 13721-39-6 | 10 mM | S2000 | ATPase | Sodium orthovanadate is the chemical compound Na3VO4 and contains the tetrahedral VO43. It is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.
Elvitegravir (GS-9137) | f7-L1700-06 | 697761-98-1, 697762-15-5 (sodium salt) | 10 mM | S2001 | Integrase | Elvitegravir is a human immunodeficiency virus integrase inhibitor with EC50 of 0.7, 2.8 and 1.4 for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD.
Maraviroc | f8-L1700-06 | 376348-65-1, 674782-29-7 | 10 mM | S2003 | CCR5 | Maraviroc is a selectiveantagonist of the CCR5co-receptorwith an in vitroIC50 of 0.1 to 4.5 nMand in vitro IC90 0.6to 13.4 nM.
Vicriviroc Malate | f9-L1700-06 | 541503-81-5, 541503-48-4 (HCl), 306296-47-9 (free base) | 10 mM | S2004 | CCR5 | Vicriviroc is a CCR5 (cellular coreceptor 5) inhibitor, in vitro activity against HIV (IC90<13 nM)
Raltegravir (MK-0518) | f10-L1700-06 | 518048-05-0, 1292804-07-9 (sodium salt) | 10 mM | [NAME] | Integrase | Raltegravir (MK-0518) is anHIV integrase inhibitor, IC95 for HIV-1 in 50% normal human serum = 33 nM.
Pyrimethamine | f11-L1700-06 | 58-14-0 | 10 mM | S2006 |  | Pyrimethamine is a dihydrofolate reductase(DHFR) inhibitor with an IC50 of 15.4 nM.
Sulindac (Clinoril) | g1-L1700-06 | 38194-50-2, 63804-15-9 (sodium salt) | 10 mM | S2007 |  | Sulindac (Clinoril) is a non-steroidal anti-inflammatory drug of the arylalkanoic acid class.
Taurine | g2-L1700-06 | 107-35-7 | 10 mM | S2008 |  | Taurine, or 2-aminoethanesulfonic acid, is an organic acid.
Pramipexole dihydrochloride monohydrate | g3-L1700-06 | 191217-81-9 | 10 mM | S2011 |  | Pramipexole dihydrochloride monohydrate is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM.
Triciribine (Triciribine phosphate) | g4-L1700-06 | 35943-35-2 | 10 mM | S1117 | [NAME] | Triciribine (TCN, API-2) is a DNA synthesis inhibitor and also inhibits [NAME] and HIV-1 with IC50 of 130 nM and 20 nM, respectively.
Dextrose (D-glucose) | g5-L1700-06 | 50-99-7 | 10 mM | S2123 |  | Dextrose (D-glucose), a simple sugar (monosaccharide), is an important carbohydrate in biology.
Mestranol | g6-L1700-06 | 72-33-3 | 10 mM | S2125 |  | Mestranol is the 3-methyl ether of ethinylestradiol. It was the estrogen used in many of the first oral contraceptives.
Naftopidil (Flivas) | g7-L1700-06 | 57149-07-2 | 10 mM | S2126 | Adrenergic Receptor | Naftopidil is a selective α1-adrenergic receptor antagonist or alpha blocker with a Ki of 58.3 nM.
S-(+)-Rolipram | g8-L1700-06 | 85416-73-5 | 10 mM | S2127 | PDE | S-(+)-Rolipram is a less active enantiomer of the PDE4 inhibitor with an EC50 of 1.0 µM.
Fudosteine | g9-L1700-06 | 13189-98-5 | 10 mM | S2129 |  | Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.
Atropine | g10-L1700-06 | 5908-99-6 | 10 mM | S2130 |  | Atropine sulfate monohydrate is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 2.5 nM.
Gabapentin (Neurontin) | g11-L1700-06 | 60142-96-3, 60142-95-2 (HCl), 63562-00-5 (sodium salt) | 10 mM | S2133 | GABA Receptor | Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analogue.
AZD8330 | h1-L1700-06 | 869357-68-6 | 10 mM | S2134 | MEK | AZD8330 (RRY-424704，ARRY-704) is an orally active, selective MEK inhibitor with an IC50 of 7 nM.
Neratinib (HKI-272) | h2-L1700-06 | 698387-09-6, 915942-22-2 (Maleic acid) | 10 mM | S2150 | HER2, EGFR | Neratinib is an orally available, irreversible tyrosine kinase inhibitor with IC50 of 59 nM and 92 nM for [NAME] and [NAME], respectively.
LDE225 (NVP-LDE225, Erismodegib) | h3-L1700-06 | 956697-53-3, 1270169-93-1, 1218778-76-7 (HCl) | 10 mM | S2151 | Smoothened | LDE225 (NVP-LDE225) is a novel and specific, orally bioavailable [NAME] inhibitor with an IC50 of 11 nM.
[NAME] (Dabigatran) | h4-L1700-06 | 211915-06-9, 872728-81-9 (methanesulfonate), 1019206-66-6 (HCl) | 10 mM | S2154 |  | Dabigatran etexilate ([NAME]) is an anticoagulant from the class of the direct thrombin inhibitors.
KW 2449 | h5-L1700-06 | 1000669-72-6 | 10 mM | S2158 | Flt, Bcr-Abl, [NAME] | KW-2449 is a multi-kinase inhibitor of FLT3 (IC50 at 6.6pM), ABL (IC50 at 14pM), ABL-T315I and [NAME] kinase.
RAF265 (CHIR-265) | h6-L1700-06 | 927880-90-8, 1009568-00-6 (Fumaric acid) | 10 mM | S2161 | Raf, VEGFR | RAF265 (CHIR-265) is an oral, highly selective RAF and VEGFR kinase inhibitor with IC50 of of 5 to 10 μM.
ITF2357 (Givinostat) | h8-L1700-06 | 732302-99-7, 497833-27-9 (free base) | 10 mM | S2170 | HDAC | ITF2357 (Givinostat) is an orally active, potent inhibitor of histone deacetylases (HDACs) with IC50 values of 7.5-16 nM.
AG14361 | h9-L1700-06 | 328543-09-5 | 10 mM | S2178 | PARP | AG14361 is a potent poly (ADP-ribose) polymerase ([NAME]) inhibitor with a GI50 of 10.9 µM.
LY2784544 | h10-L1700-06 | 1229236-86-5, 1229236-87-6 (HCl) | 10 mM | S2179 | JAK | LY2784544 is a small molecule selective mutant JAK2 kinase inhibitor with an IC50 of 68 nM.
MLN2238 | h11-L1700-06 | 1072833-77-2 | 10 mM | S2180 | Proteasome | MLN-2238 is a potent reversible and specific β5 site of the 20S proteasome inhibitor with an IC50 value of 3.4 nM.
SB 743921 | a1-L1700-07 | 940929-33-9, 618430-39-0 (free base) | 10 mM | S2182 | Kinesin | SB743921 is a second generation, highly potent and active KSP inhibitor with a Ki of 0.1 nM for KSP (Eg5).
GSK461364 | a2-L1700-07 | 929095-18-1, 1000873-97-1 | 10 mM | S2193 | PLK | GSK 461364 is a potent small molecule [NAME]-like kinase 1 (PLK1) inhibitor with a Ki of 2.2 nM.
R406 | a3-L1700-07 | 841290-81-1, 841290-82-2 (methanesulfonate) | 10 mM | S2194 | Syk, Flt | R406 is an orally available spleen tyrosine kinase inhibitor with an IC50 of 41 nM.
BIBR 953 (Dabigatran etexilate, Pradaxa) | a4-L1700-07 | 211914-51-1 | 10 mM | S2196 | Thrombin | [NAME] 953(Dabigatran) is a reversible, competitive, direct thrombin inhibitor.
SGI-1776 free base | a5-L1700-07 | 1025065-69-3, 1173928-26-1 (2H2O4S) | 10 mM | S2198 | Pim | SGI-1776, a member of the imidazo[1,2-b]pyridazine chemical class.The IC50 of SGI-1776 for the three isoforms of the Pim kinase family, Pim-1, Pim-2, and Pim-3, were in the low nanomolar range (7 ± 1.8 nmol/L, 363 ± 27.6 nmol/L, and 69 ± 9.2 nmol/L).
BMS 794833 | a6-L1700-07 | 1174046-72-0, 1174161-83-1 (HCl) | 10 mM | S2201 | c-Met, VEGFR | BMS-794833 is a potent ATPcompetitive Met/VEGFR-2 kinase inhibitor and it also inhibits [NAME] (Met family),Axl and Flt-3 with IC50 values <3 nM.
PIK-293 | a7-L1700-07 | 900185-01-5 | 10 mM | S2207 | PI3K | PIK-293 is a PI3-K inhibitor.PIK-293 inhibit the p110α, [NAME], p110δ, and [NAME] with IC50 of 100uM,25uM,0.24uM,and 10uM.
(-)-Epigallocatechin gallate | a8-L1700-07 | 989-51-5 | 10 mM | S2250 |  | (-)-Epigallocatechin gallate is a potent anti-oxidant polyphenol flavonoid isolated from green tea.
(-)-Huperzine A | a9-L1700-07 | 102518-79-6 | 10 mM | S2251 |  | (-)-Huperzine A is an acetylcholinesterase inhibitor and NMDA receptor antagonist with an IC50 of 126 μM for NMDA-induced current.
(+)-Usniacin (D-Usnic acid) | a10-L1700-07 | 7562-61-0 | 10 mM | S2252 |  | (+)-Usniacin (D-Usnic acid) is a naturally occurring dibenzofuran derivative found in several lichen species.
3-Indolebutyric acid (IBA) | a11-L1700-07 | 133-32-4 | 10 mM | S2253 |  | 3-Indolebutyric acid (IBA) is a plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products.
4-Methylumbelliferone (4-MU) | b1-L1700-07 | 90-33-5 | 10 mM | S2256 |  | 4-Methylumbelliferone is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.
[NAME] ([NAME]) | b2-L1700-07 | 531-75-9 | 10 mM | S2258 |  | [NAME] ([NAME]) is a toxin found in horse chestnuts.
SRT1720 | b3-L1700-07 | 1001645-58-4, 925434-55-5 (free base), 1001908-88-8 (TFA) | 10 mM | S1129 | Sirtuin | SRT1720 is a selective SIRT1 activator with EC1.5 of 0.16 [NAME]
[NAME] | b4-L1700-07 | 29883-15-6 | 10 mM | S2260 |  | [NAME] is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds.
Andrographolide | [NAME] | 5508-58-7 | 10 mM | S2261 |  | Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata.
Apigenin | b6-L1700-07 | 520-36-5 | 10 mM | S2262 | P450 | Apigenin is a potent CYP2C9 inhibitor.
Arbutin (Uva, p-Arbutin) | b7-L1700-07 | 497-76-7 | 10 mM | S2263 |  | [NAME] (Uvasol, p-Arbutin) is a tyrosinase inhibitor with an IC50 of 1.09 [NAME]
Artemether (SM-224) | b8-L1700-07 | 71963-77-4 | 10 mM | S2264 |  | Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.
Artesunate | b9-L1700-07 | 88495-63-0 | 10 mM | S2265 |  | Artesunate is part of the artemisinin group of drugs that treat malaria and a semi-synthetic derivative of artemisinin.
Asiatic acid | b10-L1700-07 | 464-92-6 | 10 mM | S2266 | p38 MAPK | Asiatic acid is the aglycone of asiaticoside isolated from the plant Centella asiatica, commonly used in wound healing.
Azomycin (2-Nitroimidazole) | b11-L1700-07 | 527-73-1 | 10 mM | S2267 |  | Azomycin (2-Nitroimidazole) is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica.
[NAME] | c1-L1700-07 | 491-67-8 | 10 mM | S2268 | P450 | [NAME] is a CYP2C9 and prolyl endopeptidase inhibitor.
[NAME] | c2-L1700-07 | 21967-41-9 | 10 mM | S2269 |  | [NAME] is a known prolyl endopeptidase inhibitor and affects the GABA receptors.
Bergenin (Cuscutin) | c3-L1700-07 | 477-90-7 | 10 mM | S2270 |  | Bergenin (Cuscutin) is trihydroxybenzoic acid glycoside and the C-glycoside of 4-O-methyl gallic acid.
Berberine Hydrochloride | c4-L1700-07 | 633-65-8 | 10 mM | S2271 |  | Berberine Hydrochloride is a quaternary ammonium salt from the group of isoquinoline alkaloids.
β-Sitosterol | c5-L1700-07 | 83-46-5 | 10 mM | S2273 |  | β-Sitosterol is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol.
Bilobalide | c6-L1700-07 | 33570-04-6 | 10 mM | S2276 |  | Bilobalide is a biologically active terpenic trilactone present in Ginkgo biloba.
Caffeic acid | c7-L1700-07 | 331-39-5 | 10 mM | S2277 |  | Caffeic acid is a hydroxycinnamic acid, a naturally occurring organic compound.
Chlorogenic acid | c8-L1700-07 | 327-97-9 | 10 mM | S2280 |  | Chlorogenic acid is a hydroxycinnamic acid and a member of a family of naturally occurring organic compounds.
Chrysin | c9-L1700-07 | 480-40-0 | 10 mM | S2281 |  | Chrysin is a naturally occurring flavone chemically extracted from the blue passion flower ([NAME] caerulea).
Cinchonidine | c10-L1700-07 | 485-71-2 | 10 mM | S2282 |  | Cinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry.
Brivanib alaninate (BMS-582664) | c11-L1700-07 | 649735-63-7 | 10 mM | S1138 | VEGFR | A multiple inhibitor of VEGFR( IC50 of VEGFR-2(25 nM), VEGFR-1 (380nM), VEGFR-3 (10 nM)); FGFR ([NAME] (IC50=148 nM), FGFR-2 (IC50 =125 nM), and FGFR-3 (IC50 = 68 nM))tyrosine kinases
Cryptotanshinone | d1-L1700-07 | 35825-57-1 | 10 mM | S2285 | STAT | Cryptotanshinone is a major tanshinone isolated from Salvia miltiorrhiza that exhibits multiple activities.
Cyclosporin A (Cyclosporine A) | d2-L1700-07 | 59865-13-3, 55126-45-9, 56645-58-0 | 10 mM | S2286 |  | Cyclosporin A (Cyclosporine A) is an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system.
Cytisine (Baphitoxine, Sophorine) | d3-L1700-07 | 485-35-8 | 10 mM | S2287 |  | Cytisine is a nicotinic acetylcholine receptor agonist.
[NAME] HCl | d4-L1700-07 | 850173-95-4, 850305-06-5 (free base) | 10 mM | S1139 | Opioid Receptor | [NAME] HCl is a δ-opioid receptor agonist with Ki of 0.8 nM.
Dihydroartemisinin (DHA) | d5-L1700-07 | 71939-50-9 | 10 mM | S2290 |  | Dihydroartemisinin (DHA) is a semi-synthetic derivative of artemisinin and isolated from the traditional Chinese herb Artemisia annua.
Diosgenin | d6-L1700-07 | 512-04-9 | 10 mM | S2291 |  | Diosgenin is a steroid sapogenin and the precursor for the semisynthesis of progesterone which in turn was used in early combined oral contraceptive pills.
Diosmin | d7-L1700-07 | 520-27-4 | 10 mM | S2292 |  | Diosmin is a semisynthetic phlebotropic drug and a member of the flavonoid family.
DL-Carnitine hydrochloride | d8-L1700-07 | 461-05-2 | 10 mM | S2293 |  | DL-Carnitine hydrochloride is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.
Ecdysone | d9-L1700-07 | 3604-87-3 | 10 mM | S2294 |  | Ecdysone is a steroidal prohormone of the major insect molting hormone 20-hydroxyecdysone, which is secreted from the prothoracic glands.
Emodin | d10-L1700-07 | 518-82-1 | 10 mM | S2295 |  | Emodin is a purgative resin, 6-methyl-1,3,8-trihydroxyanthraquinone, from rhubarb, the buckthorn and Japanese Knotweed (Fallopia japonica).
Enoxolone ([NAME]) | d11-L1700-07 | 471-53-4 | 10 mM | S2296 |  | Enoxolone is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice.
Ergosterol | e1-L1700-07 | 57-87-4 | 10 mM | S2297 |  | Ergosterol is a sterol and a biological precursor (a provitamin) to vitamin D2.
Fisetin (Fustel) | e2-L1700-07 | 528-48-3 | 10 mM | S2298 |  | Fisetin (Fustel) is a potent sirtuin activating compound (STAC) and an agent that modulates sirtuins.
[NAME] (Formononetol) | e3-L1700-07 | 485-72-3 | 10 mM | S2299 |  | [NAME] (Formononetol) is a phytoestrogen from the root of Astragalus membranaceus and an O-methylated isoflavone.
Fumalic acid (Ferulic acid) | e4-L1700-07 | 1135-24-6 | 10 mM | S2300 |  | Fumalic acid (Ferulic acid) is a hydroxycinnamic acid and a type of organic compound found in the [NAME] assafoetida [NAME] or Ligusticum chuanxiong.
Andarine (GTX-007) | e5-L1700-07 | 401900-40-1 | 10 mM | S1140 | Androgen Receptor | Andarine (GTX-007) is a selective nonsteroidal androgen receptor (AR) agonist with Ki of 4 nM.
[NAME] acid | e6-L1700-07 | 1405-86-3 | 10 mM | S2302 |  | [NAME] acid is a widely used anti-inflammatory agent isolated from the licorice root.
[NAME] | e7-L1700-07 | 303-45-7, 40112-23-0, 732279-01-5 | 10 mM | S2303 | 5-alpha Reductase | Gossypol is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
Gramine | e8-L1700-07 | 87-52-5 | 10 mM | S2304 |  | Gramine is a naturally occurring indole alkaloid present in several plant species.
Gynostemma Extract | e9-L1700-07 | 80321-63-7 | 10 mM | S2306 |  | Gynostemma Extract is a saponins extract derived from the [NAME] pentaphyllum.
Hesperetin | e10-L1700-07 | 520-33-2 | 10 mM | S2308 | Histamine Receptor | Hesperetin is a bioflavonoid and, to be more specific, a flavanone.
Hesperidin | e11-L1700-07 | 520-26-3 | 10 mM | S2309 |  | Hesperidin is a flavanone glycoside found abundantly in citrus fruits.
Honokiol | f1-L1700-07 | 35354-74-6 | 10 mM | [NAME] | [NAME], MEK | Honokiol is a biphenolic compound present in the cones, bark, and leaves of Magnolia grandifloris.
Hyodeoxycholic acid (HDCA) | f2-L1700-07 | 83-49-8 | 10 mM | S2311 |  | Hyodeoxycholic (HDCA) acid is a secondary bile acid, one of the metabolic byproducts of intestinal bacteria.
Icariin | f3-L1700-07 | 489-32-7 | 10 mM | S2312 | PDE | Icariin is a flavonol and PDE5 inhibitor with IC50 of 1.0, 0.75, and 1.1 μM for PDE5A1, A2, and [NAME], respectively.
Rutaecarpine (Rutecarpine) | f4-L1700-07 | 84-26-4 | 10 mM | S2349 |  | Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs.
Indole-3-carbinol | f5-L1700-07 | 700-06-1 | 10 mM | S2313 |  | Indole-3-carbinol is produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables.
Kaempferol | f6-L1700-07 | 520-18-3 | 10 mM | S2314 |  | [NAME] is a natural flavonol, a type of flavonoid, that has been isolated from plant sources.
Kinetin (6-Furfuryladenine) | f7-L1700-07 | 525-79-1 | 10 mM | S2316 |  | Kinetin (6-Furfuryladenine) is a kind of cytokinin, a class of plant hormone that promotes cell division. Kinetin is often used in plant tissue culture for inducing formation of callus (in conjunction with auxin) and to regenerate shoot tissues from callus.
L (+)-Rhamnose Monohydrate | f8-L1700-07 | 10030-85-0 | 10 mM | S2317 |  | L(+)-Rhamnose ([NAME]) is a naturally-occurring deoxy sugar.
Limonin | f9-L1700-07 | 1180-71-8 | 10 mM | S2319 |  | [NAME] is also known as limonoate D-ring-lactone and limonoic acid di-delta-lactone. Chemically, it is a member of the class of compounds known as furanolactones.
Luteolin | f10-L1700-07 | 491-70-3 | 10 mM | S2320 | PDE | Luteolin (Luteolol) is a PDE4 inhibitor and a general phosphodiesterase inhibitor, and an Interleukin 6 inhibitor.
Magnolol | f11-L1700-07 | 528-43-8 | 10 mM | S2321 |  | Magnolol (2,2'-Bichavicol) is a bioactive compound found in the bark of the Houpu magnolia (Magnolia officinalis).
Matrine ((+)-Matrine) | g1-L1700-07 | 519-02-8 | 10 mM | S2322 | Opioid Receptor | Matrine ((+)-Matrine) is an alkaloid found in plants from the [NAME] family. It has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.
Methyl-Hesperidin | g2-L1700-07 | 11013-97-1 | 10 mM | S2323 |  | Methyl-Hesperidin is a flavanone glycoside (flavonoid) (C28H34O15) found abundantly in citrus fruits. Its aglycone form is called hesperetin.
Monensin sodium salt (Coban) | g3-L1700-07 | 22373-78-0 | 10 mM | S2324 |  | Monensin sodium salt (Coban), isolated from Streptomyces cinnamonensis, is a well-known representative of naturally polyether ionophore antibiotics.
Morin hydrate (Aurantica) | g4-L1700-07 | 6202-27-3 | 10 mM | S2325 |  | Morin hydrate (Aurantica) is a chemical compound. Morin can be used to test for the presence of aluminum or tin in a solution, since it forms characteristically fluorescent coordination complexes with them.
[NAME] (Cannabiscetin) | g5-L1700-07 | 529-44-2 | 10 mM | S2326 |  | [NAME]) is a naturally occurring flavonol, a flavonoid found in many grapes, berries, fruits, vegetables, herbs, as well as other plants.
Myricitrin (Myricitrine) | g6-L1700-07 | 17912-87-7 | 10 mM | S2327 |  | Myricitrin (Myricitrine) is a chemical compound. It can be isolated from the root bark of Myrica cerifera ([NAME], a small tree native to North America) and in Chrysobalanus icaco.
Nalidixic acid (NegGram) | g7-L1700-07 | 389-08-2 | 10 mM | S2328 |  | Nalidixic acid (NegGram) is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Naringin (Naringoside) | g8-L1700-07 | 10236-47-2 | 10 mM | S2329 |  | Naringin (Naringoside) is a flavanone glycoside. It is a major flavonoid in grapefruit and gives the grapefruit juice its bitter taste.
Neohesperidin dihydrochalcone (Nhdc) | g9-L1700-07 | 20702-77-6 | 10 mM | S2331 |  | Neohesperidin dihydrochalcone (Nhdc), sometimes abbreviated to neohesperidin DC or simply NHDC, is an artificial sweetener derived from citrus.
[NAME] (Hexamethoxyflavone) | g10-L1700-07 | 478-01-3 | 10 mM | S2333 |  | [NAME] (Hexamethoxyflavone) is a chemical compound. It is an O-methylated flavone, a flavonoid isolated from citrus peels like in tangerine.
Oleanolic Acid (Caryophyllin) | g11-L1700-07 | 508-02-1 | 10 mM | S2334
Oridonin (Isodonol) | h1-L1700-07 | 28957-04-2 | 10 mM | S2335 |  | Oridonin(Isodonol), an entkaurane diterpenoid isolated from Rabdosia rubescens, is an important traditional Chinese herbal remedy.
Orotic acid (6-Carboxyuracil) | h2-L1700-07 | 65-86-1 | 10 mM | S2336 |  | Orotic acid (6-Carboxyuracil) is a heterocyclic compound and an acid.
[NAME] (Osthol) | h3-L1700-07 | 484-12-8 | 10 mM | S2337 |  | [NAME] (Osthol) is a type of coumarin.
Oxymatrine (Matrine N-oxide) | h4-L1700-07 | 16837-52-8 | 10 mM | S2338 |  | Oxymatrine (Matrine N-oxide) is one of components of the root of [NAME] flavescens.
Paeonol (Peonol) | h5-L1700-07 | 552-41-0 | 10 mM | S2339 |  | Paeonol (Peonol) is a major component extracted from Chinese herbs moutan cortex and Cynanchum paniculatum .
Parthenolide ((-)-Parthenolide) | h6-L1700-07 | 20554-84-1 | 10 mM | S2341 |  | Parthenolid e((-)-Parthenolide) is a sesquiterpene lactone which occurs naturally in the plant feverfew (Tanacetum parthenium).
[NAME] (Dihydronaringenin) | h7-L1700-07 | 60-82-2 | 10 mM | S2342 |  | [NAME] (Dihydronaringenin) is a dihydrochalcone, a type of polyphenol.
Phlorizin (Phloridzin) | h8-L1700-07 | 60-81-1 | 10 mM | S2343 |  | Phlorizin (Phloridzin) is a toxic 2'-glucoside of phloretin.
Piperine (1-Piperoylpiperidine) | h9-L1700-07 | 94-62-2 | 10 mM | S2344 |  | Piperine (1-Piperoylpiperidine) is the alkaloid responsible for the pungency of black pepper and long pepper, along with chavicine (an isomer of piperine). It has also been used in some forms of traditional medicine and as an insecticide.
Puerarin ([NAME]) | h10-L1700-07 | 3681-99-0 | 10 mM | S2346 |  | Puerarin(Kakonein) is a 5-HT2C receptor and benzodiazepine site antagonist.
Quercetin dihydrate (Sophoretin) | h11-L1700-07 | 6151-25-3 | 10 mM | S2347 |  | Quercetin, a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds.
[NAME] (Rutoside) | a1-L1700-08 | 153-18-4 | 10 mM | S2350 |  | [NAME], a flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc.
[NAME] (Salicoside, Salicine) | a2-L1700-08 | 138-52-3 | 10 mM | S2351 |  | [NAME] (Salicoside, Salicine) is an alcoholic β-glycoside that contains D-glucose. [NAME] is an anti-inflammatory agent that is produced from willow bark.
MK-8245 | a3-L1700-08 | 1030612-90-8 | 10 mM | S1158 | Dehydrogenase | MK-8245 is an inhibitor of stearoyl-CoA desaturase (SCD) which targets the liver with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1.
Sclareol | a4-L1700-08 | 515-03-7 | 10 mM | S2354 |  | Sclareol is a fragrant chemical compound found in clary sage (Salvia sclarea), from which it derives its name. It is classified as a bicyclic diterpene alcohol.
Sclareolide (Norambreinolide) | a5-L1700-08 | 564-20-5 | 10 mM | S2355 |  | Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product derived from various plant sources including Salvia sclarea, Salvia yosgadensis, and cigar tobacco.
Shikimic acid (Shikimate) | a6-L1700-08 | 138-59-0 | 10 mM | S2356 |  | Shikimic acid (Shikimate), more commonly known as its anionic form shikimate, is an important biochemical intermediate in plants and microorganisms.
Silibinin (Silybin) | a7-L1700-08 | 22888-70-6 | 10 mM | S2357 |  | Silibinin (Silybin) is the major active constituent of silymarin.
Silymarin (Silybin B) | a8-L1700-08 | 65666-07-1 | 10 mM | S2358 |  | Silymarin (Silybin B), a strong novel free radical scavenger, is used for treatment of patients with acute brain infarction.
[NAME]) | a9-L1700-08 | 115-53-7 | 10 mM | S2359 |  | [NAME]) is traditionally used in herbal medicine in these countries, as a treatment for rheumatism and arthritis.
Stigmasterol (Stigmasterin) | a10-L1700-08 | 83-48-7 | 10 mM | S2361 |  | Stigmasterol (Stigmasterin) is used as a precursor in the manufacture of synthetic progesterone.
Synephrine (Oxedrine) | a11-L1700-08 | 94-07-5 | 10 mM | S2362 | Androgen Receptor | Synephrine (Oxedrine) is a drug commonly used for weight loss.
Tangeretin (Tangeritin) | b1-L1700-08 | 481-53-8 | 10 mM | S2363 |  | Tangeretin (Tangeritin) is a citrus flavonoids.
Tanshinone I | b2-L1700-08 | 568-73-0 | 10 mM | S2364 |  | Tanshinone I is isolated from Danshen.
Tanshinone IIA (Tanshinone B) | b3-L1700-08 | 568-72-9 | 10 mM | S2365 |  | Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae [NAME], a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases.
[NAME] ([NAME]) | b4-L1700-08 | 480-18-2 | 10 mM | S2366 |  | Taxifolin(Dihydroquercetin) is a flavanonol, a type of flavonoid.
Tetrahydropapaverine hydrochloride | [NAME] | 6429-04-5 | 10 mM | S2367 |  | Tetrahydropapaverine, one of the TIQs and an analogue of salsolinol and tetrahydropapaveroline, has been reported to have neurotoxic effects on dopamine neurons.
Theobromine (3,7-Dimethylxanthine) | b6-L1700-08 | 83-67-0 | 10 mM | S2368 |  | Theobromine (3,7-Dimethylxanthine) is a xanthine alkaloid that is used as a bronchodilator and as a vasodilator.
Troxerutin | b7-L1700-08 | 7085-55-4 | 10 mM | S2369 |  | Troxerutin (Trihydroxyethylrutin) is a flavonol, a type of flavonoid.
[NAME] acid (Malol) | b8-L1700-08 | 77-52-1 | 10 mM | S2370 |  | [NAME] acid (Malol) is a pentacyclic triterpene acid, used in cosmetics.
Vanillylacetone | b9-L1700-08 | 122-48-5 | 10 mM | S2371 |  | Vanillylacetone is similar in chemical structure to other flavor chemicals such as vanillin and eugenol. It is used as a flavor additive in spice oils and in perfumery to introduce spicy aromas.
Yohimbine hydrochloride (Antagonil) | b10-L1700-08 | 65-19-0 | 10 mM | S2373 |  | Yohimbine (Antagonil) has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
5-hydroxytryptophan (5-HTP) | b11-L1700-08 | 56-69-9 | 10 mM | S2374 |  | 5-Hydroxytryptophan (5-HTP) is decarboxylated to serotonin (5-hydroxytryptamine or 5-HT) by the enzyme aromatic-L-amino-acid decarboxylase with the help of [NAME].
Aloin (Barbaloin) | c1-L1700-08 | 1415-73-2 | 10 mM | S2375 |  | Aloin (Barbaloin) is a potent tyrosinase inhibitor with an IC50 of 97 µM for HeLaS3 cells.
Ammonium Glycyrrhizinate (AMGZ) | c2-L1700-08 | 1407-03-0 | 10 mM | S2376 |  | Mono-ammonium glycyrrhizinate (AMGZ) is a unique product derived from Licorice root and has an extremely sweet taste.
[NAME] (4-Methylgenistein) | c3-L1700-08 | 491-80-5 | 10 mM | S2377 |  | [NAME] (4-Methylgenistein) is an O-methylated isoflavone. It is a natural organic compound in the class of phytochemicals known as flavonoids.
[NAME] bromide (Scopolamine butylbromide) | c4-L1700-08 | 149-64-4 | 10 mM | S2378 |  | [NAME] bromide, is a peripherally acting antimuscarinic, anticholinergic agent used as an abdominal-specific antispasmodic.
[NAME] (Gastrodine) | c5-L1700-08 | 62499-27-8 | 10 mM | S2383 |  | [NAME] ([NAME]) is a polyphenol. It is the glucoside of 4-hydroxybenzyl alcohol (gastrodigenin).
Hordenine | c6-L1700-08 | 539-15-1 | 10 mM | S2385 |  | Hordenine (N,N-dimethyl-4-hydroxyphenylethylamine) is a phenylethylamine alkaloid with antibacterial and antibiotic properties.
Indirubin | c7-L1700-08 | 479-41-4 | 10 mM | S2386 | GSK-3 | Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 75 nM and 0.19 μM.
Lappaconite Hydrobromide | c8-L1700-08 | 97792-45-5 | 10 mM | S2387 |  | Lappaconite Hydrobromide is a kind of alkaloid extracted from Aconitum sinomontanum Nakai and has anti-inflammatory effects.
L-carnitine (Levocarnitine) | c9-L1700-08 | 541-15-1 | 10 mM | S2388 |  | L-carnitine (Levocarnitine) is constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
[NAME] (Naringin DC) | c10-L1700-08 | 18916-17-1 | 10 mM | S2389 |  | [NAME] (Naringin DC) is a new-style sweetening agent and an artificial sweetener derived from naringin.
[NAME] (Piceid) | c11-L1700-08 | 65914-17-2 | 10 mM | S2390 |  | [NAME] (Piceid), 3,4’,5-trihydroxystilbene-3-β-mono-D-glucoside, the crystal component extracted from the root stem of perennial herbage Polygonum Cuspidatum Sieb.et Zucc.
Quercetin (Sophoretin) | d1-L1700-08 | 117-39-5 | 10 mM | S2391 | PI3K, PKC, [NAME], Sirtuin | Quercetin is [NAME] and PKC inhibitor with IC50 of 3.8 μM and 15µg/ml.
Sesamin (Fagarol) | d2-L1700-08 | 607-80-7 | 10 mM | S2392 |  | Sesamin (Fagarol) is a lignan isolated from the bark of [NAME] plants and from sesame oil.
[NAME] ([NAME]) | d3-L1700-08 | 50-70-4 | 10 mM | S2393 |  | [NAME] ([NAME]) is a sugar alcohol and a sugar substitute.
[NAME] (Physcione) | d4-L1700-08 | 521-61-9, 140670-52-6 | 10 mM | S2395 |  | [NAME] (Physcion; physcione; parietin) is one of the major components of [NAME] decoction used in the treatment of inflammation.
Salidroside (Rhodioloside) | d5-L1700-08 | 10338-51-9 | 10 mM | S2396 |  | Salidroside (Rhodioloside; [NAME]) is a glucoside compound with an IC50 of 4.99 ± 0.23 μg/mL for the proliferation of SACC-2 cells.
Palmatine chloride | d6-L1700-08 | 10605-02-4 | 10 mM | S2397 |  | Palmatine hydrochloride (Palmatine chloride (6CI,7CI); [NAME]) is a hydrochloride salt of palmatine which is a protoberberine alkaloid.
Coenzyme Q10(CoQ10) | d7-L1700-08 | 303-98-0, 13448-14-1, 55127-92-9, 55870-43-4 | 10 mM | S2398 |  | Coenzyme Q10 (ubiquinone, ubidecarenone, coenzyme Q) is a component of the electron transport chain and participates in aerobic cellular respiration.
[NAME] ([NAME]) | d8-L1700-08 | 27200-12-0 | 10 mM | [NAME] |  | [NAME] ([NAME] (flavanol); [NAME]) is a natural antioxidant with good prospects.
[NAME] ([NAME]) | d9-L1700-08 | 478-43-3, 202053-60-9 (monosodium salt) | 10 mM | S2400 |  | Rhein(Monorhein; NSC 38629; Rheic acid; Rheinic acid) is a constituent of rhubarb which was isolated from the fresh rhizome of Rheum coreanum Nakai.
Sodium Danshensu | d10-L1700-08 | 67920-52-9, 23028-17-3 | 10 mM | S2401 | P450 | [NAME] is a mono sodium of danshensu which is a compound isolated from Salvia miltiorrhiza Bge.
[NAME]) | d11-L1700-08 | 860-79-7, 541513-15-9 (XFumaric acid) | 10 mM | S2402 |  | Cyclovirobuxine D (bebuxine; Cyclovirobuxine) is an active compound extracted from Buxus microphylla, which has been used for treating acute myocardial ischemia.
Tetrandrine (Fanchinine) | e1-L1700-08 | 518-34-3, 32434-13-2 (2HCL) | 10 mM | S2403 | Calcium Channel | Tetrandrine (Fanchinine; Hanfangchin A) is a calcium channel blocker with an IC50 of 38.23± 25.77 [NAME]
Isoliquiritigenin | e2-L1700-08 | 961-29-5, 78918-29-3 | 10 mM | S2404 |  | Isoliquiritigenin (GU 17) is a strong nod gene- and glyceollin resistance-inducing flavonoid from soybean root exudate.
Sophocarpine | e3-L1700-08 | 6483-15-4, 33823-32-4 (HCl) | 10 mM | S2405 |  | Sophocarpine is a human ether-à-go-go-related gene (HERG) inhibitor with an IC(50) of about 0.2 mM.
Chrysophanic acid (Chrysophanol) | e4-L1700-08 | 481-74-3 | 10 mM | S2406 | EGFR, mTOR | Chrysophanic acid (Chrysophanol) is a EGFR/mTOR pathway inhibitor.
Curcumol | e5-L1700-08 | 4871-97-0 | 10 mM | S2407 |  | Curcumol is a common traditional Chinese medicine with antitumor activities.
Amantadine hydrochloride (Symmetrel) | e6-L1700-08 | 665-66-7 | 10 mM | S2451 | Dopamine Receptor | Amantadine hydrochloride (Symmetrel) is used to treat or prevent infections of the respiratory tract caused by a certain virus
Amfebutamone (Bupropion) | e7-L1700-08 | 31677-93-7 | 10 mM | S2452 | Dopamine Receptor | Amfebutamone (Bupropion) is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4µM for the reuptake of dopamine and norepinephrine, respectively.
Benserazide | e8-L1700-08 | 14919-77-8 | 10 mM | S2453 | Dopamine Receptor | Benserazide hydrochloride (Serazide) is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.
[NAME] hydrochloride ([NAME]) | e9-L1700-08 | 18010-40-7 | 10 mM | S2454 |  | [NAME] hydrochloride ([NAME]) is a more potent cAMP production inhibitor with an IC50 of 2.3 µM.
Bethanechol chloride | e10-L1700-08 | 590-63-6 | 10 mM | S2455 | AChR | Carbamyl-beta-methylcholine chloride (Bethanechol chloride) is a selective muscarinic receptor agonist without any effect on nicotinic receptors.
Chlorpromazine (Sonazine) | e11-L1700-08 | 69-09-0 | 10 mM | S2456 | Dopamine Receptor, Potassium Channel | Chlorpromazine hydrochloride (Sonazine) is a dopamine and potassium channel inhibitor with IC50 of 6.1 and 16 µM for nward-rectifying K+ currents and time-independent outward currents.
Clindamycin hydrochloride (Dalacin) | f1-L1700-08 | 21462-39-5 | 10 mM | S2457 |  | Clindamycin hydrochloride (Dalacin) is the hydrated hydrochloride salt of clindamycin which is a semisynthetic antibiotic.
Clonidine hydrochloride (Catapres) | f2-L1700-08 | 4205-91-8 | 10 mM | S2458 | Adrenergic Receptor | Clonidine hydrochloride (Catapres) is a direct-acting α2 adrenergic agonist with an ED50 of 0.02±0.01 mg/kg.
Clozapine (Clozaril) | f3-L1700-08 | 5786-21-0 | 10 mM | S2459 | 5-HT Receptor | Clozapine (Clozaril) is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis.
Domperidone (Motilium) | f4-L1700-08 | 57808-66-9 | 10 mM | S2461 | Dopamine Receptor | Domperidone (Motilium) is a dopamine blocker and an antidopaminergic reagent.
Donepezil HCl (Aricept) | f5-L1700-08 | 120011-70-3 | 10 mM | S2462 | AChR | Donepezil hydrochloride (Aricept) is a centrally acting reversible acetylcholinesterase inhibitor with an IC50 of 12.3 nM.
Fenbendazole (Panacur) | f6-L1700-08 | 43210-67-9 | 10 mM | S2468 |  | Fenbendazole (Panacur) is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites with an IC5 of about 0.01 µg/ml.
Fleroxacin (Quinodis) | f7-L1700-08 | 79660-72-3 | 10 mM | S2469 |  | Fleroxacin (Quinodis) is a new broad-spectrum fluoroquinolone.
Gallamine triethiodide (Flaxedil) | f8-L1700-08 | 65-29-2 | 10 mM | S2471 | AChR | Gallamine triethiodide (Flaxedil) is a cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 µM.
Imatinib (Gleevec) | f9-L1700-08 | 152459-95-5 | 10 mM | S2475 | PDGFR | Imatinib (STI571) is a number of tyrosine kinase enzymes specific inhibitor.
Lincomycin hydrochloride (Lincocin) | f10-L1700-08 | 859-18-7 | 10 mM | S2479 |  | Lincomycin hydrochloride ([NAME]) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.
Loperamide hydrochloride | f11-L1700-08 | 34552-83-5 | 10 mM | [NAME] | Opioid Receptor | Loperamide is an opioid-receptor agonist with an ED50 of 0.15 mg/kg.
Manidipine (Manyper) | g1-L1700-08 | 89226-50-6 | 10 mM | S2481 | Calcium Channel | Manidipine (Manyper) is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM.
Manidipine dihydrochloride (CV-4093) | g2-L1700-08 | 89226-75-5 | 10 mM | S2482 | Calcium Channel | Manidipine HCl (CV-4093) is a hydrochloride salt of manidipine that is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM.
Milrinone (Primacor) | g3-L1700-08 | 78415-72-2 | 10 mM | S2484 | ATPase | Milrinone (Primacor) is a a potent and selective phosphodiesterase 3 inhibitor with an IC50 of 0.42 µM for the inhibition of FIII PDE.
Mitoxantrone Hydrochloride | g4-L1700-08 | 70476-82-3, 65271-80-9 (free base), 70711-41-0 (diacetate) | 10 mM | S2485 |  | Mitoxantrone is a type II topoisomerase inhibitor with IC50 of 2.0 µM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively.
Moroxydine | g5-L1700-08 | 3160-91-6 | 10 mM | S2486 |  | Moroxydine hydrochloride is a synthetic antiviral drug chemically belonging to the series of the  heterocyclic biguanidines.
Mycophenolic (Mycophenolate) | g6-L1700-08 | 24280-93-1 | 10 mM | S2487 |  | Mycophenolic acid (Mycophenolate) is an immunosuppressant drug used to prevent rejection in organ transplantation.
Nateglinide ([NAME]) | g7-L1700-08 | 105816-04-4 | 10 mM | S2489 | Potassium Channel | Nateglinide ([NAME]) is an insulin secretagog agent that lowers blood glucose levels by stimulating insulin secretion from the pancreas.
Neostigmine bromide (Prostigmin) | g8-L1700-08 | 114-80-7 | 10 mM | S2490 | AChR | Neostigmine bromide (Prostigmin) is a reversible acetylcholinesterase inhibitor.
Novobiocin sodium (Albamycin) | g9-L1700-08 | 1476-53-5 | 10 mM | S2492 |  | Novobiocin (Albamycin) is a very potent bacterial DNA gyrase and human organic anion transporters with [NAME] of of 14.87 ± 0.40 µM for hOAT1, 4.77 ± 1.12 µM for hOAT3, and 90.50 ± 7.50 µM for hOAT4
Olopatadine hydrochloride (Opatanol) | g10-L1700-08 | 140462-76-6 | 10 mM | S2494 | Histamine Receptor | Olopatadine hydrochloride (Opatanol) is a histamine blocker and mast cell stabilizer with an IC50 of 559 µM for the release of histamine.
Oxymetazoline hydrochloride | g11-L1700-08 | 2315-02-8 | 10 mM | S2495 | Adrenergic Receptor | Oxymetazoline hydrochloride is an α1 and α2 adrenergic receptor agonist.
[NAME] | h1-L1700-08 | 82571-53-7 | 10 mM | S2496 | Factor Xa | [NAME] is a potent and selective thromboxane A2 synthetase inhibitor with an IC50 of 4 nM.
Pancuronium (Pavulon) | h2-L1700-08 | 15500-66-0 | 10 mM | S2497 | AChR | Pancuronium (Pavulon) is a competitive acetylcholine antagonist with an IC50 of 5.5 ± 0.5 nM.
Quinine hydrochloride dihydrate | h3-L1700-08 | 6119-47-7 | 10 mM | S2502 |  | Quinine hydrochloride dihydrate is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste.
[NAME] (Acetorphan) | h4-L1700-08 | 81110-73-8 | 10 mM | S2503 | Opioid Receptor | [NAME] is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 µM.
Rosiglitazone maleate | h5-L1700-08 | 155141-29-0 | 10 mM | S2505 | PPAR | Rosiglitazone maleate is an anti-diabetic drug in the thiazolidinedione class of drugs.
Salbutamol sulfate (Albuterol) | h6-L1700-08 | 51022-70-9 | 10 mM | S2507 | Adrenergic Receptor | Salbutamol(Albuterol) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM.
Sotalol (Betapace) | h7-L1700-08 | 959-24-0 | 10 mM | S2509 | Adrenergic Receptor | Sotalol (Betapace) is a non-selective beta blocker and a potassium channel blocker with an IC50 of 43 µM.
Spectinomycin  hydrochloride | h8-L1700-08 | 21736-83-4 | 10 mM | S2510 |  | Spectinomycin hydrochloride is a new parenteral antibiotic prepared from Streptomyces spectabilis.
[NAME] (STA-9090) | h9-L1700-08 | 888216-25-9, 1143571-94-1 | 10 mM | S1159 | HSP (e.g. [NAME]) | [NAME] is an HSP90 inhibitor with IC50 of 4 nM in OSA 8 cells.
Vardenafil (Vivanza) | h10-L1700-08 | 224785-90-4, 224785-90-4 (free base) | 10 mM | S2515 | PDE | Vardenafil(Vivanza) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
TRAM-34 | h11-L1700-08 | 289905-88-0 | 10 mM | S1160 | Potassium Channel | TRAM-34 is a selective and potent inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1) with Kd of 20 nM.
LDN193189 | a1-L1700-09 | 1062368-24-4, 1062368-62-0 (HCl) | 10 mM | S2618 | TGF-beta/[NAME] | LDN193189 is a highly potent small molecule BMP inhibitor with IC50 of 5 and 30 nM for [NAME] and ALK3, respectively.
DCC-2036 (Rebastinib) | a2-L1700-09 | 1020172-07-9, 1020172-08-0 (2HCl), 1033893-29-6 (4-methylbenzenesulfonate) | 10 mM | S2634 | Bcr-Abl | DCC-2036 is an ABL switch control inhibitor with IC50 of 0.8 and 2 nM for u-ABL1native and p-ABL1native, respectively.
PF-00562271 | a3-L1700-09 | 939791-38-5, 717907-75-0 (free base), 939791-39-6 (methanesulfonate) | 10 mM | S2672 | FAK | PF-562271 is a potent ATP-competitive FAK and proline-rich tyrosine kinase ([NAME]) inhibitor with potential antineoplastic and antiangiogenic activities.
PCI-32765 (Ibrutinib) | a4-L1700-09 | 936563-96-1 | 10 mM | S2680 | Src | PCI-32765 is a high potent irreversible BTK inhibitor with an IC50 of 0.46 nM for the purified Btk.
NVP-BSK805 | a5-L1700-09 | 1092499-93-8 (free base) | 10 mM | S2686 | JAK | NVP-BSK805 is a potent and selective quinoxaline JAK2 inhibitor with IC50 of 0.48, 0.56 and 0.58 nM for JAK2 JH1, FL JAK V617F and FL JAK2 wt, respectively.
KX2-391 | a6-L1700-09 | 897016-82-9, 1038395-65-1 (2HCl), 1080645-95-9 (methanesulfonate), 1201926-60-4 (Maleic acid) | 10 mM | S2700 | Src | KX2-391 is a synthetic, orally bioavailable small molecule and non-ATP competitive [NAME] tyrosine kinase signaling inhibitor with an IC50 of average 72 nM.
GSK1838705A | a7-L1700-09 | 1116235-97-2, 1116236-05-5 (H2O) | 10 mM | S2703 | IGF-1, ALK | GSK1838705A is a potent small-molecule IGF-IR, the insulin receptor and anaplastic lymphoma kinase (ALK) inhibitor with IC50 of 2.0, 1.6 and 0.5 nM, respectively.
Crenolanib (CP-868596) | a8-L1700-09 | 670220-88-9, 670220-93-6 (benzenesulfonate) | 10 mM | S2730 | PDGFR | Crenolanib (CP-868569) is a highly selective and potent PDGFR-α inhibitor with IC50 of 0.9 and 1.8 nM against PDGFRα and PDGFRβ, respectively.
Tofacitinib citrate (CP-690550 citrate) | a9-L1700-09 | 540737-29-9, 477600-75-2 (free base) | 10 mM | S5001 | JAK | [NAME] (CP-690550) is a novel, small molecule potent and selective JAK-3 kinase inhibitor with an IC50 of 1 nM for inhibition of the [NAME] activities.
Fenoprofen calcium | a10-L1700-09 | 34597-40-5 | 10 mM | S1823 |  | Fenoprofen calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.
Erdosteine | a11-L1700-09 | 84611-23-4 | 10 mM | S1825 |  | Erdosteine is a mucolytic which is used in treatment of excessive viscous mucus.
Adenine | b1-L1700-09 | 73-24-5 | 10 mM | S1981 | DNA/RNA Synthesis | Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry.
Adenine hydrochloride | b2-L1700-09 | 2922-28-3 | 10 mM | S1983 | DNA/RNA Synthesis | Adenine hydrochloride is a hydrochloride salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.
Candesartan cilexetil (Atacand) | b3-L1700-09 | 145040-37-5 | 10 mM | S2037 |  | Candesartan cilexetil (Atacand) is a specific nonpeptide Ang II receptor (ATR) antagonist and the prodrug of candesartan which is an ATR antagonist with an IC50 of 15 µg/kg.
LY2886721 | b4-L1700-09 | 1262036-50-9, 1262036-49-6 (HCl) | 10 mM | S2156 |  | LY2886721 is a novel potent agent that is used to treat Alzheimer's Disease in preclinical experiments.
Avasimibe (CI-1011) | [NAME] | 166518-60-1 | 10 mM | S2187 | P450 | Avasimibe (CI-1011) is a novel orally bioavailable acyl coenzyme A:cholesterol acyltransferase inhibitor with IC50 of 2.9, 13.9, 26.5 µM for CYP2C9, CYP1A2, and CYP2C19.
AZD8931 | b6-L1700-09 | 848942-61-0, 1196531-39-1 (diFumaric acid) | 10 mM | S2192 | EGFR, [NAME] | AZD8931 is a novel potent reversible small molecule epidermal growth factor receptor, ERBB2 (HER2) and ERBB3 inhibitor with an IC50 of 4, 3, 4 nM, respectively.
CYT997 | b7-L1700-09 | 917111-44-5, 917111-49-0 (2HCl), 917111-51-4 (dimethanesulfonate) | 10 mM | S2195 | [NAME] | CYT997, a small molecule inhibits the polymerization of tubulin with an IC50 of 3 μmol/L and shows an IC50 of between 1 and 100 nmol/L across a panel of cancer cell lines.
A-966492 | b8-L1700-09 | 934162-61-5 | 10 mM | S2197 | PARP | A-966492 is a highly potent and efficacious poly(ADP-ribose) polymerase (PARP) inhibitor with a [NAME] and EC50 of 1 nM.
[NAME] hemifumarate | b9-L1700-09 | 173334-58-2, 173334-57-1 (free base), 173399-03-6 (HCl) | 10 mM | S2199 | RAAS | [NAME] hemifumarate is a hemifumarate salt form of [NAME]. [NAME] is a novel orally effective direct renin inhibitor with an IC50 of 0.72 nM against renin.
Raf265 derivative | b10-L1700-09 | N/A | 10 mM | S2200 | VEGFR, Raf | Raf265 derivative is a derivative of Raf265 that is an oral, highly selective RAF and VEGFR kinase inhibitor with IC50 of of 5 to 10 μM.
NVP-BHG712 | b11-L1700-09 | 940310-85-0 | 10 mM | S2202 | VEGFR, [NAME], [NAME], Bcr-Abl | NVP-BHG712 is a small molecule specific EphB4, VEGFR2, c-raf, c-src and c-Abl kinase inhibitor with ED50 of 25 nM, 4.2, 0.4, 1.3 and 1.7μM, respectively.
PA-824 | c1-L1700-09 | 187235-37-6 | 10 mM | S1162 |  | PA-824 is an anti-tuberculosis drug for tuberculosis with MIC less than 1 μg/mL.
OSI-420 (Desmethyl Erlotinib) | c2-L1700-09 | 183320-51-6, 183321-86-0 (free base) | 10 mM | S2205 | EGFR | OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.
R935788 (Fostamatinib disodium, R788 disodium) | c3-L1700-09 | 1025687-58-4, 901119-35-5 (free base),1180490-89-4 (acetate) | 10 mM | S2206 | Syk | R935788 (Fostamatinib disodium) is a selective Syk inhibitor with an IC50 of 41 nM.
Formestane | c4-L1700-09 | 566-48-3, 127128-20-5 | 10 mM | S2208 | Aromatase | Formestane (Lentaron(R)) is a second generation selective aromatase inhibitor with an IC50 of 80 nM.
Vinflunine Tartrate | c5-L1700-09 | 1201898-17-0, 162652-95-1 (free base) | 10 mM | S2209 | [NAME] | Vinflunine Tartrate is a tartrate salt of vinflunine that is a new microtubule inhibitor agent with IC50 of 18.8 nM.
AZ 960 | c6-L1700-09 | 905586-69-8 | 10 mM | S2214 | JAK | AZ 960 is a novel small molecule JAK2 kinase inhibitor with an IC50 and [NAME] of 3 mM and 0.45 nM in vitro, respectively.
DAPT (GSI-IX) | c7-L1700-09 | 208255-80-5 | 10 mM | S2215 | Gamma-secretase, Beta Amyloid | DAPT (GSI-IX) is a γ-secretase inhibitor with IC50 of 0.12 and 0.2 μM for total [NAME] and Aβ42 levels, respectively.
Mubritinib (TAK 165) | c8-L1700-09 | 366017-09-6 | 10 mM | S2216 | HER2 | Mubritinib (TAK 165) is a potent EGFR and p34cdc2 inhibitor with IC50 of 6 nM and 0.2 µM, respectively.
Irinotecan HCl Trihydrate (Campto) | c9-L1700-09 | 136572-09-3 | 10 mM | S2217 | Topoisomerase | Irinotecan hydrochloride trihydrate is a hydrochloride trihydrate of irinotecan (Camptosar, Campto, CPT-11) which is a topoisomerase I inhibitor with IC50 of 15.8 and 5.17 μM for LoVo cells and HT-29 cells, respectively.
PP242 | c10-L1700-09 | 1092351-67-1, 1173019-76-5 (H2O) | 10 mM | S2218 | mTOR | PP242 is a novel potent and selective mTOR inhibitor with an IC50 of 8 nM.
Cyt387 | c11-L1700-09 | 1056634-68-4, 1056636-08-8 (XHCl) | 10 mM | S2219 | JAK | Cyt387 is an ATP-competitive small molecule [NAME]/JAK2 inhibitor with IC50 of 11 and 18 nM for [NAME] and JAK2, respectively.
Apatinib (YN968D1) | d1-L1700-09 | 811803-05-1 | 10 mM | S2221 | VEGFR | Apatinib (YN968D1) is a small-molecule selective multitargeted tyrosine kinase inhibitor with an IC50 of 2.43 nM for the inhibition of VEGFR2.
TAME | d2-L1700-09 | 901-47-3, 1784-03-8 (HCl) | 10 mM | S2225 | APC | TAME is a small molecule anaphase-promoting complex/cyclosome (APC) inhibitor with an IC50 of 12 μM.
CAL-101 (GS-1101) | d3-L1700-09 | 870281-82-6 | 10 mM | S2226 | PI3K | CAL-101 is a potent PI3K p110δ inhibitor with an IC50 of 65 nM.
PIK-294 | d4-L1700-09 | 900185-02-6 | 10 mM | S2227 | PI3K | PIK-294 is a highly selective p110 inhibitor with an IC50 of 3 nM.
AT13387 | d5-L1700-09 | 912999-49-6, 1019889-41-8 (HCl) | 10 mM | S1163 | HSP (e.g. [NAME]) | AT13387 is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells.
[NAME] (SB-497115-GR) | d6-L1700-09 | 496775-61-2 | 10 mM | S2229 |  | [NAME] (SB-497115-GR, [NAME], Revolade) is a small molecule agonist of the c-mpl (TpoR) receptor with an IC50 of 0.69 μM for the inhibition of hERG K+ channel tail current.
LY2157299 | d7-L1700-09 | 700874-72-2, 924898-09-9 (H2O) | 10 mM | S2230 | TGF-beta/[NAME] | LY2157299 is a novel selective small molecule transforming growth factor beta receptor (TGF-βR) kinase inhibitor with IC50 of 86 nM and 2 nM for TβR1 and 2 nM, respectively.
Telatinib (BAY 57-9352) | d8-L1700-09 | 332012-40-5, 332013-24-8 (4-methylbenzenesulfonate), 332013-28-2 (2HCl) | 10 mM | S2231 | VEGFR, PDGFR, c-Kit | Telatinib (BAY 57-9352) is an orally available, potent multitargeted VEGFR-2, VEGFR-3, PDGFR-β and c-Kit tyrosine kinases inhibitor with an IC50 of 19 nM for the inhibition of VEGFR-2 autophosphorylation.
Ketanserin (Vulketan Gel) | d9-L1700-09 | 74050-98-9 | 10 mM | S2232 | 5-HT Receptor | Ketanserin ([NAME]) is specific 5-HT2A serotonin receptor antagonist with a Ki of 2.5 nM for rat and human 5-HT2A.
Esomeprazole sodium (Nexium) | d10-L1700-09 | 161796-78-7, 119141-88-7 (free base) | 10 mM | S2233 | ATPase | Esomeprazole sodium (Nexium) is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.
BI6727 (Volasertib) | d11-L1700-09 | 755038-65-4, 946161-17-7 (3HCl) | 10 mM | S2235 | PLK | BI 6727 is a highly potent [NAME]-like kinase inhibitor with an IC50 of 0 .87 nM.
Fesoterodine fumarate (Toviaz) | e1-L1700-09 | 286930-03-8, 286930-02-7 (free base), 345663-07-2 (HCl) | 10 mM | S2240 | AChR | Fesoterodine fumarate (Toviaz) is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.
[NAME] (Lenvatinib) | e2-L1700-09 | 417716-92-8, 857890-39-2 (methanesulfonate), 857890-31-4 (HCl) | 10 mM | S1164 | VEGFR | [NAME] ([NAME]) is a multi-target inhibitor of VEGFR2 and VEGFR3 with IC50 of 4 nM and 5.2 nM, respectively.
WP1130 | e3-L1700-09 | 856243-80-6 | 10 mM | S2243 | DUB, Bcr-Abl | WP1130 is a novel selective small molecular deubiquitinase (DUB) inhibitor and a Bcr/Abl destruction pathway activator with an IC50 of 1.8 μM for K562 cells.
AR-42 (HDAC-42) | e4-L1700-09 | 935881-37-1 | 10 mM | S2244 | HDAC | [NAME] is a novel HDAC inhibitor with an IC50 of 0.61 μM for acute lymphoblastic leukemia (697) cell lines.
CP-466722 | e5-L1700-09 | 1080622-86-1 | 10 mM | S2245 | ATM | CP-466722 is rapidly reversible potential ATM kinase inhibitor.
[NAME] (CB7630) | e6-L1700-09 | 154229-18-2, 877265-41-3 (methanesulfonate), 877319-47-6 (HCl) | 10 mM | S2246 | P450 | Abiraterone Acetate (CB 7630) is a highly active and selective 17α-hydroxylase/17,20 lyase (CYP17A1) inhibitor with an IC50 of 72 nM.
BKM120 (NVP-BKM120) | e7-L1700-09 | 944396-07-0, 1312445-63-8 (HCl), 1370351-44-2 (0.5H2O) | 10 mM | S2247 | PI3K | BKM120 (NVP-BKM120) is a bioavailable specific oral pan-class I phosphatidylinositol 3-kinase (PI3K) kinase inhibitor.
cx-4945 (Silmitasertib) | e8-L1700-09 | 1009820-21-6, 1309357-15-0 (sodium salt) | 10 mM | S2248 | PKC | CX-4945 (CX 4945) is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a [NAME] and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively.
Ostarine (MK-2866) | e9-L1700-09 | 841205-47-8, 1235370-13-4 | 10 mM | [NAME] | Androgen Receptor | Ostarine (GTx-024, MK-2866, Enobosarm, S-22) is a selective androgen receptor modulator (SARM) with [NAME] of 3.8 nM.
Neohesperidin | e10-L1700-09 | 13241-33-3 | 10 mM | [NAME] |  | Neohesperidin is an antioxidant agent with an IC50 of 22.31 µg/ml in the 1,1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay.
Xanthone (Genicide) | e11-L1700-09 | 90-47-1 | 10 mM | S2372 |  | Xanthone is an organic compound. It can be prepared by the heating of phenyl salicylate.
Dioscin (Collettiside III) | f1-L1700-09 | 19057-60-4 | 10 mM | S2379 |  | Dioscin (Collettiside III) is a saponin extracted and isolated from Polygonatum Zanlanscianense Pamp with IC50 of 2.6, 0.8, 7.5, and 4.5 μM for the inhibition of the growth of the MDA-MB-435, H14, HL60, and HeLa cell lines, respectively.
Diosmetin ([NAME] ether) | f2-L1700-09 | 520-34-3 | 10 mM | S2380 |  | [NAME] ether) is a bioflavonoid found in spearmint, oregano, and many other plants.
D-Mannitol (Osmitrol) | f3-L1700-09 | 69-65-8 | 10 mM | S2381 |  | D-Mannitol(Osmitrol) is an osmotic diuretic agent and a weak renal vasodilator.
Evodiamine (Isoevodiamine) | f4-L1700-09 | 518-17-2 | 10 mM | S2382 |  | Evodiamine (Isoevodiamine) is an alkaloid extract from a plant known as [NAME].
[NAME] (Hydroxybrazilin) | f5-L1700-09 | 517-28-2 | 10 mM | S2384 |  | [NAME] ([NAME]) is a compound that forms strongly colored complexes with certain metal ions, notably Fe(III) and Al(III) salts and a kind of stain in histology.
TAK-700 (Orteronel) | f6-L1700-09 | 566939-85-3 | 10 mM | S1195 | CYP17 | TAK-700 (Orteronel) is a potent and highly selective rat and human 17,20-lyase inhibitor with IC50 of 54 nM and 38 nM, respectively.
Gentamycin sulfate (Gentacycol) | f7-L1700-09 | 1405-41-0 | 10 mM | S2472 |  | Gentamycin (Gentacycol) is an aminoglycoside antibiotic and was isolated from [NAME] species
Hexestrol (Bibenzyl) | f8-L1700-09 | 84-16-2 | 10 mM | S2473 | Estrogen/progestogen Receptor | Hexestrol (Bibenzyl) is a novel type of 17βhydroxysteroid dehydrogenase, AKR1C1and AKR1C2  potent inhibitor with IC50 of 0.8, 9.5, 2.8 µM, respectively and exhibits strong affinity for estrogen receptors.
Itraconazole (Sporanox) | f9-L1700-09 | 84625-61-6 | 10 mM | [NAME] |  | Itraconazole (Sporanox) is a triazole antifungal agent.
Olanzapine (Zyprexa) | f10-L1700-09 | 132539-06-1 | 10 mM | S2493 | 5-HT Receptor, Dopamine Receptor | Olanzapine (Zyprexa) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.
Ribavirin (Copegus) | f11-L1700-09 | 36791-04-5 | 10 mM | [NAME] |  | Ribavirin is an anti-viral agent indicated for severe RSV infection (individually), hepatitis C infection and other viral infections.
Scopolamine hydrobromide | g1-L1700-09 | 114-49-8 | 10 mM | S2508 |  | Scopolamine is a competitive muscarinic acetylcholine receptor with an IC50 of 55.3 ± 4.3 nM.
Maprotiline hydrochloride | g2-L1700-09 | 10347-81-6 | 10 mM | S2517 | Reuptake inhibitor | Maprotiline hydrochloride (Deprilept, Ludiomil, Psymion) is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant.
Naphazoline hydrochloride (Naphcon) | g3-L1700-09 | 550-99-2 | 10 mM | S2519 | Adrenergic Receptor | Naphazoline hydrochloride (Naphcon) is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.
Epinephrine bitartrate (Adrenalinium) | g4-L1700-09 | 51-42-3 | 10 mM | S2521 | Adrenergic Receptor | Epinephrine bitartrate (D02149, Adrenalinium) is alpha- and beta-adrenergic receptor stimulator.
L-Adrenaline (Epinephrine) | g5-L1700-09 | 51-43-4 | 10 mM | S2522 |  | L-Adrenaline (Epinephrine) belongs to a group of the compounds known as catecholamines.
Phenytoin sodium ([NAME]) | g6-L1700-09 | 630-93-3 | 10 mM | S2524 | Sodium Channel | Phenytoin sodium ([NAME]) is an inactive voltage-gated sodium channel stabilizer.
[NAME] (Lepitoin) | g7-L1700-09 | 57-41-0 | 10 mM | S2525 | Sodium Channel | [NAME] (Lepitoin; NSC 8722; Phenytek; Phenytoine; Sodanton; [NAME]) is an inactive voltage-gated sodium channel stabilizer.
Alizarin | g8-L1700-09 | 72-48-0 | 10 mM | S2526 |  | Alizarin is an organic compound and an important prominent dye.
Methacycline hydrochloride ([NAME]) | g9-L1700-09 | 3963-95-9 | 10 mM | S2527 |  | Methacycline hydrochloride ([NAME]) is a tetracycline antibiotic.
Dopamine hydrochloride ([NAME]) | g10-L1700-09 | 62-31-7, 51-61-6 (free base) | 10 mM | S2529 | Dopamine Receptor | Dopamine hydrochloride ([NAME]) is a catecholamine neurotransmitter present in a wide variety of animals,And a dopamine D1-5 receptors agonist.
7-Aminocephalosporanic acid | g11-L1700-09 | 957-68-6 | 10 mM | S2530 |  | 7-Aminocephalosporanic acid is a key intermediate required for the production of most of the clinically used cephalosporin derivatives.
[NAME] (Asaronaldehyde) | h1-L1700-09 | 4460-86-0 | 10 mM | S2531 | COX | [NAME] (Asaronaldehyde) is a selective COX-2 inhibitor
L-Ascorbyl 6-palmitate | h2-L1700-09 | 137-66-6 | 10 mM | S2532 |  | L-Ascorbyl 6-palmitate is a synthetic lipophilic ascorbic acid derivative.
Ritodrine hydrochloride (Yutopar) | h3-L1700-09 | 23239-51-2 | 10 mM | S2533 | Adrenergic Receptor | Ritodrine hydrochloride (DU 21220; [NAME]; NSC 291565; Pre-Par) is a hydrochloride salt of ritodrine which is a β-2 adrenergic receptor agonist.
Isoconazole nitrate (Travogen) | h4-L1700-09 | 24168-96-5 | 10 mM | S2534 |  | Isoconazole nitrate (Travogen) is an azole antifungal reagent.
Econazole nitrate ([NAME]) | h5-L1700-09 | 24169-02-6 | 10 mM | S2535 |  | Econazole nitrate ([NAME]) is an imidazole class antifungal medication.
Miconazole ([NAME]) | h6-L1700-09 | 22916-47-8 | 10 mM | S2536 |  | Miconazole ([NAME]) is an imidazole antifungal agent.
Secnidazole (Flagentyl) | h7-L1700-09 | 3366-95-8 | 10 mM | S2537 |  | Secnidazole (Flagentyl) is a nitroimidazole anti-infective.
Acetanilide (Antifebrin) | h8-L1700-09 | 103-84-4 | 10 mM | S2538 |  | Acetanilide (Antifebrin) is an aniline derivative and has possess analgesic.
Lomefloxacin hydrochloride (Maxaquin) | h9-L1700-09 | 98079-52-8 | 10 mM | S2539 |  | Lomefloxacin hydrochloride (Maxaquin) is a hydrochloride salt of lomefloxacin and is a fluoroquinolone antibiotic.
[NAME] ([NAME]) | h10-L1700-09 | 83-88-5 | 10 mM | S2540 |  | [NAME] (vitamin B2) is an easily absorbed micronutrient with a key role in maintaining health in humans and other animals.
Clomipramine hydrochloride ([NAME]) | h11-L1700-09 | 17321-77-6 | 10 mM | S2541 | 5-HT Receptor | Clomipramine hydrochloride ([NAME]) is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with [NAME] of 0.14, 54 and 3 nM, respectively.
Phenformin hydrochloride | a1-L1700-10 | 834-28-6 | 10 mM | S2542 | AMPK | Phenformin hydrochloride is a hydrochloride salt of phenformin that is an anti-diabetic drug from the biguanide class.
[NAME] hydrochloride | a2-L1700-10 | 103980-44-5 | 10 mM | S2543 |  | [NAME] hydrochloride is a hydrochloride of ceftiofur that is a broad spectrum cephalosporin.
Cefprozil hydrate (Cefzil) | a3-L1700-10 | 121123-17-9 | 10 mM | S2544 |  | Cefprozil hydrate (Cefzil) is a second-generation cephalosporin type antibiotic.
Tiotropium Bromide (Spiriva, BA 679BR) | a4-L1700-10 | 136310-93-5 | 10 mM | S2546 | AChR | Tiotropium Bromide (Spiriva, BA 679BR) is a synthetic quaternary ammonium antimuscarinic agent and is a muscarinic receptor antagonist.
Tiotropium Bromide hydrate | a5-L1700-10 | 139404-48-1 | 10 mM | S2547 | AChR | Tiotropium Bromide hydrate is a monohydrate of tiotropium bromide (Spiriva; Tiova; [NAME]; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist.
Trospium chloride (Sanctura) | a6-L1700-10 | 10405-02-4 | 10 mM | S2549 | AChR | Trospium chloride (Sanctura) is a competitive muscarinic cholinergic receptor antagonist.
Tolterodine tartrate (Detrol LA) | a7-L1700-10 | 124937-52-6 | 10 mM | S2550 | AChR | Tolterodine tartrate (Detrol LA) is a tartrate salt of tolterodine that is a competitive muscarinic receptor antagonist.
Azelastine hydrochloride (Astelin) | a8-L1700-10 | 79307-93-0 | 10 mM | S2552 | Histamine Receptor | Azelastine is a potent, second-generation, selective, histamine antagonist.
5-Aminolevulinic acid hydrochloride | a9-L1700-10 | 5451-09-2 | 10 mM | S2553 |  | 5-Aminolevulinic acid is an intermediate in heme biosynthesis in the body and the universal precursor of tetrapyrroles.
Clarithromycin (Biaxin, Klacid) | a10-L1700-10 | 81103-11-9 | 10 mM | S2555 | P450 | Clarithromycin is a macrolide antibiotic and a CYP3A4 substrate and inhibitor.
Rosiglitazone (Avandia) | a11-L1700-10 | 122320-73-4 | 10 mM | S2556 | PPAR | Rosiglitazone (Avandia) is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively.
Terbinafine hydrochloride ([NAME]) | b1-L1700-10 | 78628-80-5 | 10 mM | S2557 |  | Terbinafine hydrochloride ([NAME]) is a hydrochloride salt of terbinafine that is a synthetic allylamine antifungal and a squalene epoxidase inhibitor with an IC50 of 30 nM for Candida albicans.
Dimesna | b2-L1700-10 | 16208-51-8 | 10 mM | S1201 |  | Dimesna is an uroprotective agent used to decrease urotoxicity.
Cortisone acetate (Cortone) | b3-L1700-10 | 50-04-4, 29253-51-8, 478614-09-4 | 10 mM | S2559 |  | Cortisone acetate (Cortone) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.
Clomifene citrate (Serophene) | b4-L1700-10 | 50-41-9 | 10 mM | S2561 | Estrogen/progestogen Receptor | Clomifene citrate (Serophene) is a selective estrogen receptor modulator.
Hydralazine hydrochloride | [NAME] | 304-20-1 | 10 mM | S2562 |  | Hydralazine hydrochloride is a hydrochloride salt of hydralazine (Apresoline) that is a direct-acting smooth muscle relaxant with an IC50 of 1.9 mM.
[NAME] sodium (Cloxacap) | b6-L1700-10 | 7081-44-9 | 10 mM | S2564 |  | [NAME] sodium (Cloxacap) is a sodium salt of cloxacillin (Cloxapen, Cloxacap，Orbenin) that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin.
Amoxicillin sodium ([NAME]) | b7-L1700-10 | 34642-77-8 | 10 mM | S2565 |  | Amoxicillin (Amox) is a moderate- spectrum, bacteriolytic, β-lactam antibiotic.
Isoprenaline hydrochloride | b8-L1700-10 | 51-30-9 | 10 mM | S2566 | Adrenergic Receptor | Isoprenaline hydrochloride is a beta-adrenergic agonist.
Neomycin sulfate | b9-L1700-10 | 1405-10-3 | 10 mM | S2568 |  | Neomycin sulphate belongs to a class of antibiotics known as the aminoglycosides.
Prednisolone acetate (Omnipred) | b10-L1700-10 | 52-21-1 | 10 mM | S2570 |  | Prednisolone acetate is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.
YM201636 | b11-L1700-10 | 371942-69-7, 371933-96-9 (2HCl) | 10 mM | S1219 | PI3K | YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM.
Tetracaine hydrochloride (Pontocaine) | c1-L1700-10 | 136-47-0 | 10 mM | S2573 | Calcium Channel | Tetracaine hydrochloride (Pontocaine) is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.
Trazodone hydrochloride ([NAME]) | c2-L1700-10 | 25332-39-2 | 10 mM | S2582 | 5-HT Receptor | Trazodone hydrochloride ([NAME]) is a hydrochloride salt of trazodone that is a serotonin antagonist and reuptake inhibitor with a Kd of 0.16 [NAME]
Tioxolone | c3-L1700-10 | 4991-65-5 | 10 mM | S2603 | Carbonic Anhydrase | Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor with a Ki of 91 nM.
Dehydroepiandrosterone (DHEA) | c4-L1700-10 | 53-43-0 | 10 mM | S2604 | Androgen Receptor | Dehydroepiandrosterone (DHEA) is a 19-carbon endogenous natural steroid hormone.
Fluocinonide (Vanos) | c5-L1700-10 | 356-12-7 | 10 mM | S2608 |  | Fluocinonide (Vanos) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.
Clorsulon | c6-L1700-10 | 60200-06-8 | 10 mM | S2613 |  | Clorsulon is a competitive 8-phosphoglycerate kinase and phospho-glyceromutase inhibitor.
TAK-733 | c7-L1700-10 | 1035555-63-5 | 10 mM | [NAME] | MEK | TAK-733 is highly potent and selective novel [NAME] allosteric site inhibitor with an IC50 of 3.2 nM.
MG-132 | c8-L1700-10 | 133407-82-6 | 10 mM | S2619 | Proteasome | MG132 is a potent cell-permeable proteasome and calpain inhibitor with IC50 of 0.1 and 1.2 μM for the inhibition of proteasome and calpain, respectively.
GSK256066 | c9-L1700-10 | 801312-28-7, 801311-47-7 (XHCl), 801315-14-0 (HCl) | 10 mM | S2620 | PDE | GSK256066 is an exceptionally high affinity and selective PDE4 inhibitor with an IC50 of 3.2 pM for PDE4B.
AZD5438 | c10-L1700-10 | 602306-29-6 | 10 mM | [NAME] | CDK | AZD5438 is a potent cyclin-dependent kinase (cdk) 1, 2 and 9 inhibitor with IC50 of 16, 6 and 20 nM, respectively.
PP-121 | c11-L1700-10 | 1092788-83-4 | 10 mM | S2622 | DNA-PK, mTOR, PDGF | PP121 is a multitargeted dual receptor tyrosine kinases inhibitor with IC50 of 0.052, 1.4, 0.15, 1.1, 0.06, 0.01and 0.002 μM for p110α, [NAME], p110δ, [NAME], DNA-PK, mTOR and PDGFR, respectively.
[NAME] mecarbil (CK-1827452) | d1-L1700-10 | 873697-71-3, 921625-14-1 | 10 mM | S2623 | ATPase | [NAME] mecarbil (CK-1827452) is a selective sarcomere-directed cardiac myosin activator with an E50 of 0.6 μM.
OSI-027 | d2-L1700-10 | 936890-98-1, 1187559-66-5 (sodium salt) | 10 mM | S2624 | mTOR | OSI027 is a potent mammalian target of rapamycin (mTOR) kinase inhibitor. Rea
[NAME] (IC-83) | d3-L1700-10 | 911222-45-2 | 10 mM | S2626 | Chk | [NAME] (IC-83) is a highly selective Chk 1 inhibitor with potential antitumor activity.
Tubastatin A hydrochloride | d4-L1700-10 | 1310693-92-5, 1252003-15-8 ,1239262-52-2 (TFA) | 10 mM | S2627 | HDAC | Tubastatin A hydrochloride is a potent selective HDAC6 inhibitor with an IC50 of 15 nM.
PF-05212384 (PKI-587) | d5-L1700-10 | 1197160-78-3 | 10 mM | S2628 | mTOR, PI3K | PKI-587 is a highly potent dual PI3K/mTOR kinase inhibitor with IC50 of 0.4 nM and <0.1 μM for PI3K-α and mTOR, respectively.
PNU-120596 | d6-L1700-10 | 501925-31-1 | 10 mM | S2629 | AChR | PNU-120596 is a potent and selective positive allosteric α7 neuronal nicotinic acetylcholine receptors modulator with an EC50 of 0.2 μM.
GW3965 HCl | d7-L1700-10 | 405911-17-3, 405911-09-3 (free base) | 10 mM | S2630 | [NAME] | GW3965 is a synthetic selective, active non-steroidal liver X receptor (LXR) agonist with EC50 of 0.19 and 0.03 μM for hLXRα and hLXRβ, respectively.
URB597 | d8-L1700-10 | 546141-08-6 | 10 mM | S2631 | FAAH | URB597 is a relatively selective fatty acid amide hydrolase (FAAH) inhibitor with IC50 of 4.6 and 0.5 nM in brain membranes and intact neurons, respectively.
BMS-806 (BMS 378806) | d9-L1700-10 | 357263-13-9 | 10 mM | S2632 | gp120/CD4 | BMS-806 (BMS 378806) is a small molecule gp120/CD4 inhibitor with an IC50 of median 5 nM.
NPS-2143 (SB262470) | d10-L1700-10 | 284035-33-2, 324523-20-8 (HCl) | 10 mM | S2633 | CaSR | NPS-2143 is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively.
CCT128930 | d11-L1700-10 | 885499-61-6 | 10 mM | S2635 | [NAME] | CCT128930 is a novel potent ATP-competitive, AKT inhibitor with an IC50 of 6 nM.
A66 | e1-L1700-10 | 1166227-08-2 | 10 mM | S2636 | PI3K | A66 is a highly specific and selective p110α inhibitor with IC50 of 32,30 and 43 nM for p110α, p110α/E545K, p110α/H1047R, respectively.
[NAME] | e2-L1700-10 | 1374598-80-7, 1000413-72-8 (free base) | 10 mM | S2637 | GPR | TAK-875 is a potent, selective and orally bioavailable GPR40 agonist with an EC50 of 0.072 [NAME]
NU7441(KU-57788) | e3-L1700-10 | 503468-95-9 | 10 mM | S2638 | DNA-PK, PI3K | NU7441 is a potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor with IC50 of 0.01, 1.7 and 5 μM for DNA-PK, mTOR and PI 3-K, respectively.
SNX-2112 | e4-L1700-10 | 908112-43-6, 945626-71-1 | 10 mM | S2639 | HSP | SNX-2112 is a potent synthetic heat shock protein 90 inhibitor with an IC50 of 0.92 μM for K562 cells.
PF-04929113 (SNX-5422) | e5-L1700-10 | 908115-27-5, 1173111-67-5 (methanesulfonate) | 10 mM | S2656 | HSP | PF-04929113 (SNX-5422) is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM.
GSK2126458 | e6-L1700-10 | 1086062-66-9 | 10 mM | S2658 | PI3K, mTOR | GSK2126458 is a highly potent PI3K and mTOR inhibitor with an app Ki of 19 pM for PI3K.
5-hydroxymethyl tolterodine (PNU 200577) | e7-L1700-10 | 207679-81-0, 380636-50-0 (Fumaric acid) | 10 mM | S2659 | AChR | 5-hydroxymethyl tolterodine (PNU 200577) is a potent muscarinic receptor antagonist with a Kb and a pA2 of 0.84 nM and 9.14, respectively.
[NAME] | e8-L1700-10 | 471905-41-6 | 10 mM | S2660 | Gamma-secretase | [NAME] is a potent gamma secretase (γ-secretase) inhibitor in clinical development with an IC50 of 5 nM for Aβ40 in human SH-SY5Y cells.
[NAME] | e9-L1700-10 | 1144068-46-1 | 10 mM | S2661 | mTOR | [NAME] is a highly potent, ATP-competitive and specific mTOR kinase inhibitor with an IC50 of 0.19 nM.
ICG-001 | e10-L1700-10 | 780757-88-2 | 10 mM | S2662 | Wnt/beta-catenin | ICG-001 is a selective Wnt/β-catenin signalling inhibitor with an IC50 of 3μM.
WAY-100635 HCl | e11-L1700-10 | 146714-97-8, 162760-96-5 (free base) | 10 mM | S2663 | 5-HTReceptor | WAY-100635 is a potent and selective 5-hydroxytryptamine1A antagonist with an IC50 of 0.95 ± 0.12 nM for 5-HT
Clinofibrate | f1-L1700-10 | 30299-08-2 | 10 mM | S2664 | RAAS | Clinofibrate is a new hypelipidemic agent and a competitive hydroxymethylglutaryl coenzyme A reductase with an IC50 of 0.47 mM.
Ciprofibrate | f2-L1700-10 | 52214-84-3, 128660-46-8 | 10 mM | S2665 | PPAR | Ciprofibrate is a peroxisome proliferator-activated receptor agonist.
PF-3845 | f3-L1700-10 | 1196109-52-0 | 10 mM | S2666 | FAAH | PF-3845 is a potent, selective and irreversible fatty acid amide hydrolase (FAAH) inhibitor with a Ki of 0.23 μM.
S/GSK1349572 (GSK1349572) | f4-L1700-10 | 1051375-16-6, 1051375-19-9 (sodium salt) | 10 mM | S2667 | Integrase | S/GSK1349572 (GSK 1349572) is a novel potent integrase inhibitor with an IC50 of 2.7 nM in vitro.
WYE-687 | f5-L1700-10 | 1062161-90-3, 1198178-23-2 (HCl) | 10 mM | S2668 | mTOR | WYE-687 is a potent ATP-competitive mTOR inhibitor with an IC50 of 7 nM.
LY310762 | f6-L1700-10 | 192927-92-7, 379215-96-0 (free base) | 10 mM | S2669 | 5-HT Receptor | LY310762 is a potent and selective 5-HT1D serotonin receptor antagonist with an EC50 of 31 nM.
A-674563 | f7-L1700-10 | 552325-73-2 | 10 mM | S2670 | [NAME], CDK, PKA | A-674563 is a potent selective protein kinase B/Akt inhibitor with an IC50 of 14 nM.
AS-252424 | f8-L1700-10 | 900515-16-4 | 10 mM | S2671 | PI3K | AS-252424 is a potent and selective PI3k γ inhibitor with IC50 of 33 and 935 nM for PI3Kγ and PI3Kα, respectively.
GSK1120212 (Trametinib) | f9-L1700-10 | 871700-17-3, 871702-06-6 (sodium salt) | 10 mM | S2673 | MEK | GSK1120212 (Trametinib) is a reversible, selective, allosteric MEK1/MEK2 kinase activity inhibitor with IC50 of 0.7 and 0.9 nM for MEK1 and MEK2.
BRL-15572 | f10-L1700-10 | 193611-72-2, 734517-40-9 (free base), 1173022-77-9 (HCl) | 10 mM | S2677 | 5-HT Receptor | BRL-15572 is a hydrochloride salt form of BRL-15572 which is a selective serotonin receptor subtype 5-HT1D antagonist with an IC50 of 260 μM.
NSC-207895 (XI-006) | f11-L1700-10 | 58131-57-0 | 10 mM | S2678 | p53, [NAME], DNA/RNA Synthesis | NSC-207895 (XI-006) is a derivative of nitrobenzofuroxan and an anticancer agent with an EC50 of 1 μM.
Flavopiridol hydrochloride | g1-L1700-10 | 131740-09-5, 146426-40-6 (free base), 358739-41-0 (TFA) | 10 mM | S2679 | CDK | Flavopiridol hydrochloride is a pan-cdk inhibitor.
AS-604850 | g2-L1700-10 | 648449-76-7 | 10 mM | S2681 | PI3K | AS-604850 is a selective, ATP-competitive PI3Kγ inhibitor with IC50 of 0.25, >20, >20, and 4.5 µM for the human recombinant γ, δ, β, and α isoforms, respectively.
WAY-600 | g3-L1700-10 | 1062159-35-6 | 10 mM | S2689 | mTOR | WAY-600 is a potent ATP-competitive mTOR inhibitor with an IC50 of 9 nM.
ADX-47273 | g4-L1700-10 | 851881-60-2 | 10 mM | S2690 | GluR | ADX-47273 is a novel, potent and selective metabotropic glutamate receptor 5 allosteric modulator with an EC50 of 170 nM in human embryonic kidney 293 cells expressing rat mGlu5.
BMY 7378 | g5-L1700-10 | 21102-95-4, 21102-94-3 (free base) | 10 mM | S2691 | 5-HT Receptor | BMY 7378 is a 5-HT1A receptor weak partial agonist/antagonist and α1D-adrenergic receptor antagonist with [NAME] values of 2.8 and 0.6 μM for cloned rat rat α1A and hamster α1B receptors, respectively.
TG101209 | g6-L1700-10 | 936091-14-4 | 10 mM | S2692 | Flt, JAK, c-RET | TG101209 is a potent and small molecule JAK2-selective kinase inhibitor with IC50 of 6, 25, 17 and 169 nM for JAK2, FLT3, RET and [NAME], respectively.
WAY-362450 | g7-L1700-10 | 629664-81-9 | 10 mM | S2694 | FXR | WAY-362450 is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.
GDC-0980 (RG7422) | g8-L1700-10 | 1032754-93-0, 1309043-78-4, 1309384-87-9 | 10 mM | S2696 | mTOR, PI3K | GDC-0980 (RG7422) is a selective, dual [NAME] and [NAME] inhibitor with IC50 of 5, 27, 7, and 14 nM for PI3Kα, β, δ, and γ, respectively.
A-769662 | g9-L1700-10 | 844499-71-4 | 10 mM | S2697 | AMPK | A-769662 is a potent, reversible AMP-activated protein kinase (AMPK) activator with an EC50 of 0.8 μM.
RS-127445 | g10-L1700-10 | 199864-87-3, 199864-86-3 (HCl), 199864-88-5 (Maleic acid) | 10 mM | S2698 | 5-HT Receptor | RS-127445 is a potent, selective and high affinity serotonin 5-HT2B receptor antagonist with a pIC50 of 10.4.
YO-01027 | g11-L1700-10 | 209984-56-5 | 10 mM | S2711 | Gamma-secretase | YO-01027 is a dipeptidic gamma-secretase inhibitor with IC50 of 2.6 and 2.9 nM for the proteolysis of APPL and Notch, respectively.
[NAME] | h1-L1700-10 | 30562-34-6 | 10 mM | S2713 | HSP | [NAME] is a benzoquinone ansamycin antibiotic that binds to Hsp90 (Heat Shock Protein 90) and alters its function.
CP-91149 | h2-L1700-10 | 186392-40-5 | 10 mM | S2717 | Phosphorylase | CP-91149 is a human liver glycogen phosphorylase α (HLGPα) inhibitor with an IC50 of 0.13 μM in the presence of 7.5 mM glucose
TAK-901 | h3-L1700-10 | 934541-31-8, 934542-50-4 (HCl), 1020203-96-6 (Fumaric acid), 1020203-86-4 (benzenesulfonate) | 10 mM | S2718 | [NAME] | TAK-901 is a small-molecule inhibitor of the serine-threonine kinase [NAME] B with potential antineoplastic activity.
AMG 900 | h4-L1700-10 | 945595-80-2 | 10 mM | S2719 | [NAME] | AMG 900 is a novel potent and highly selective Pan-aurora kinase inhibitor with an IC50 of median 3.5 nM.
ZM 336372 | h5-L1700-10 | 208260-29-1 | 10 mM | S2720 | Raf | Zm 336372 is a potent, selective c-Raf inhibitor with an IC50 of 70 nM for inhibition of human [NAME] in vitro.
PH-797804 | h6-L1700-10 | 586379-66-0, 1073667-47-6 | 10 mM | S2726 | p38 MAPK | PH-797804 is a highly selective, potent, and ATP-competitive p38 MAP kinase inhibitor with an IC50 of 2.3 nM.
PF-04691502 | h7-L1700-10 | 1013101-36-4 | 10 mM | S2743 | mTOR, PI3K, [NAME] | PF-04691502 is a potent and selective dual PI3K/mTOR inhibitor to phosphorylation of AKT T308 and AKT S473 with IC50 of 7.5 and 3.8 nM, respectively.
ATP (Adenosine-Triphosphate) | h8-L1700-10 | 987-65-5 | 10 mM | S1985 |  | ATP is a disodium salt form of adenosine-triphosphate which is a multifunctional nucleoside triphosphate.
GW 791343 hydrochloride | h9-L1700-10 | 309712-55-8, 309712-73-0 (free base) | 10 mM | S2242 | [NAME] | GW 791343 hydrochloride is a non-competitive human P2X(7) receptor inhibitor with pIC50 of about 7.1.
AG-1024 | h10-L1700-10 | 65678-07-1 | 10 mM | S1234 | IGF-1R | AG-1024 (Tyrphostin) is a specific IGF-1R and IR inhibitor with IC50 of 0.4 μM and 0.1 μM, respectively.
MDV3100 (Enzalutamide) | h11-L1700-10 | 915087-33-1 | 10 mM | S1250 | CYP17 | MDV3100 is an androgen-receptor (AR) antagonist with IC50 of 36 nM.
PD173074 | a1-L1700-11 | 219580-11-7 | 10 mM | S1264 | FGFR | PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM.
[NAME] (PLX4032) | a2-L1700-11 | 918504-65-1 | 10 mM | S1267 | Raf | PLX4032 ([NAME], RG7204, Zelboraf, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM.
BX-795 | a3-L1700-11 | 702675-74-9 | 10 mM | S1274 | PDK-1 | BX795 is a potent and specific TBK1, IKKε and PDK-1 inhibitor with IC50 of 6 nM, 41 nM and 111 nM, respectively.
BX-912 | a4-L1700-11 | 702674-56-4 | 10 mM | S1275 | PDK-1 | [NAME] is a selective potent PDK1 inhibitor with IC50 of 12 nM.
Celastrol | a5-L1700-11 | 34157-83-0, 956288-52-1 (sodium salt) | 10 mM | S1290 |  | Celastrol, a plant-derived triterpene, has anti-inflammatory and immunosuppressive activity.
Ki16425 | a6-L1700-11 | 355025-24-0 | 10 mM | S1315 | LPA Receptor | Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.
AMG-208 | a7-L1700-11 | 1002304-34-8 | 10 mM | S1316 | c-Met | AMG-208 is a highly selective c-Met inhibitor with IC50 of 9.3 nM.
Costunolide | a8-L1700-11 | 553-21-9, 11028-78-7, 25333-06-6 | 10 mM | S1319 | Telomerase | Costunolide inhibits FPTase with IC50 of 20 μM and also inhibits telomerase with IC50 of 90 μM and 65 μM in MCF-7 and MDA-MB-231 cells.
Flupirtine maleate | a9-L1700-11 | 75507-68-5, 56995-20-1 (free base), 33400-45-2 (HCl) | 10 mM | S1334 | DNA/RNA Synthesis | Flupirtine maleate is the salt form of Flupirtine, which is a non-opioid, centrally acting analgesia, muscle relaxation and neuroprotection.
Galanthamine HBr | a10-L1700-11 | 1953-04-4, 357-70-0 (free base), 5072-47-9 (HCl) | 10 mM | S1339 | AChR | Galanthamine (Razadyne, [NAME]) is an AChE inhibitor with IC50 of 14 nM.
Amonafide | a11-L1700-11 | 69408-81-7, 150091-68-2 (2HCl), 135882-21-2 (methanesulfonate) | 10 mM | S1367 | Topoisomerase | Amonafide (NSC-308847) is a selective topoisomerase II inhibitor.
Ruxolitinib (INCB018424) | b1-L1700-11 | 941678-49-5, 941678-50-8 (TFA), 1092939-15-5 (Maleic acid) | 10 mM | S1378 | JAK | INCB018424 is a JAK family inhibitor for [NAME], JAK2 and [NAME] with IC50 of 2.7 nM, 4.5 nM and 322 nM, respectively.
Staurosporine | b2-L1700-11 | 62996-74-1 | 10 mM | S1421 | PKC | Staurosporine (AM-2282) is a potent PKC inhibitor with IC50 of 2.7 nM.
Azalomycin-B | b3-L1700-11 | 37318-06-2 ,11003-23-9, 106387-86-4 | 10 mM | S1448 |  | Azalomycin-B ([NAME]) shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively.
Nanchangmycin | b4-L1700-11 | 65101-87-3,35865-33-9(free base) | 10 mM | S1450 |  | Nanchangmycin (dianemycin) is a polyether antibiotic with similar structure to dianemycin and is very active against a broad spectrum of harmful nematodes and insects but not for for mammals and plants.
[NAME] | [NAME] | 1226056-71-8, 1228446-06-7 (TFA) | 10 mM | S1459 | ROCK | [NAME] ([NAME]) is a novel ROCK inhibitor with IC50 of ~0.5 μM.
[NAME] | b6-L1700-11 | 1173900-33-8 | 10 mM | S1462 | PI3K | [NAME] is an inhibitor of PI3Kβ with IC50 of 21 nM.
Safinamide Mesylate (FCE28073) | b7-L1700-11 | 202825-46-5, 133865-89-1 (free base) | 10 mM | S1472 | MAO | Safinamide Mesylate is mesylate salt of Safinamide, which selectively and reversibly inhibits MAO-B with IC50 of 0.45 μM.
Oligomycin A | b8-L1700-11 | 579-13-5, 11030-76-5, 21307-25-5 | 10 mM | S1478 | ATPase | Oligomycins are macrolides created by Streptomyces that can be poisonous to other organisms.
LY335979 (Zosuquidar 3HCl) | b9-L1700-11 | 167465-36-3, 167354-41-8 (free base) | 10 mM | S1481 | P-gp | LY335979 (Zosuquidar) is a potent modulator of P-glycoprotein-mediated multidrug resistance with Ki of 60 nM.
MK-1775 | b10-L1700-11 | 955365-80-7, 1075739-30-8 (H2O), 1075739-32-0 (XHCl) | 10 mM | S1525 | Wee1 | MK-1775 is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM.
LY2811376 | b11-L1700-11 | 1194044-20-6, 1194043-85-0 (2HCl) | 10 mM | S1528 | Gamma-secretase | LY2811376 is a non-peptidic BACE1 inhibitor with IC50 of 239 nM/249 nM and also decreases the [NAME] secretion with EC50 of ~300 nM.
CP 673451 | c1-L1700-11 | 343787-29-1, 343787-32-6 (4-methylbenzenesulfonate) | 10 mM | S1536 | PDGFR | CP 673451 is a potent PDGFR-β inhibitor with an IC50 of 1 nM.
DMXAA (ASA404) | c2-L1700-11 | 117570-53-3, 129095-08-5 (sodium salt) | 10 mM | S1537 | VDA | DMXAA (ASA404) is a competitive inhibitor of DT-diaphorase (NAD(P)H:Quinone oxidoreductase EC 1.6.99.2) with [NAME] of 20 μM and IC50 of 62.5 μM, respectively.
Telaprevir (VX-950) | c3-L1700-11 | 402957-28-2, 569364-34-7 | 10 mM | S1538 | HCV Protease | Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 [NAME]
AM-1241 | c4-L1700-11 | 444912-48-5 | 10 mM | S1544 | Cannabinoid Receptor | AM-1241 is a selective CB2 agonist with Ki of 3.4 nM.
Dapagliflozin | c5-L1700-11 | 461432-26-8, 960404-48-2 ((2S)-1,2-propanediol, hydrate) | 10 mM | S1548 | SGLT | Dapagliflozin is a potent and selective hSGLT2 inhibitor with EC50 of 1.1 nM.
PHT-427 | c6-L1700-11 | 1191951-57-1, 1178893-77-0 | 10 mM | S1556 | [NAME] | PHT-427 is a dual [NAME] and PDPK1 inhibitor with [NAME] of 2.7 μM and 5.2 μM, respectively.
VX-809 | c7-L1700-11 | 936727-05-8, 1160221-26-0 (HCl) | 10 mM | S1565 | CFTR | VX-809 is a CFTR modulator with EC50 of 0.1 μM.
Tie2 kinase inhibitor | c8-L1700-11 | 948557-43-5 | 10 mM | S1577 | Tie-2 | Tie2 kinase inhibitor is a potent and selective Tie2 inhibitor with IC50 of 0.25 [NAME]
TWS119 | c9-L1700-11 | 601514-19-6 | 10 mM | S1590 | GSK-3 | TWS119 is a GSK-3β inhibitor with IC50 of 30 nM.
D-glutamine | c10-L1700-11 | 5959-95-5 | 10 mM | S1893 |  | D-glutamine is a D type stereoisomer of glutamine which is one of the 20 amino acids encoded by the standard genetic code.
Flutamide (Eulexin) | c11-L1700-11 | 13311-84-7 | 10 mM | S1908 | P450 (e.g. CYP17) | Flutamide ([NAME]) is an oral nonsteroidal antiandrogen agent primarily used to treat prostate cancer.
PCI-34051 | d1-L1700-11 | 950762-95-5, 1072027-64-5 | 10 mM | S2012 | HDAC | PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM.
PF 573228 | d2-L1700-11 | 869288-64-2 | 10 mM | S2013 | FAK | PF 573228 is a inhibitor of FAK with IC50 of 4 nM.
[NAME] | d3-L1700-11 | 582315-72-8 | 10 mM | S2014 | CDK | BMS265246 is a potent and selective CDK inhibitor for [NAME]/cyclin B and CDK2/cyclin E with IC50 of 6 nM and 9 nM, respectively.
Cyproterone acetate | d4-L1700-11 | 427-51-0 | 10 mM | S2042 | P450 (e.g. CYP17) | Cyproterone acetate is an androgen receptor (AR) antagonist with IC50 of 7.1 nM.
[NAME] | d5-L1700-11 | 1032823-75-8, 1032824-54-6 (HCl) | 10 mM | S2149 | GPR | GSK-1292263 is a novel GPR119 agonist.
LY2608204 | d6-L1700-11 | 1234703-40-2 | 10 mM | S2155 |  | LY2608204 activates glucokinase (GK) with EC50 of 42 nM.
LY2940680 | d7-L1700-11 | 1258861-20-9, 1258861-21-0 (HCl) | 10 mM | S2157 | Hedgehog | LY2940680 binds to the [NAME] receptor and potently inhibits Hh signaling.
PD 128907 HCl | d8-L1700-11 | 112960-16-4 (HCl), 123594-64-9 | 10 mM | S2168 | Dopamine Receptor | PD 128907 HCl is a drug used in scientific research which acts as a potent and selective agonist for the dopamine D2 and D3 receptors.
[NAME] (NVP-BGJ398) | d9-L1700-11 | 872511-34-7, 1310746-11-2 (H2O), 1310746-12-3 (methanesulfonate), 1310746-17-8 (acetate) | 10 mM | S2183 | FGFR | [NAME] (NVP-BGJ398) is a potent and selective inhibitor of FGFR1, FGFR2 and FGFR3 with IC50 of 0.9 nM, 1.4 nM and 1 nM, respectively.
AST-1306 | d10-L1700-11 | 1050500-29-2, 897383-62-9 (free base) | 10 mM | S2185 | EGFR | AST-1306 is a novel irreversible inhibitor of EGFR and ErbB4 with IC50 of 0.5 nM and 0.8 nM, respectively.
[NAME] | d11-L1700-11 | 694433-59-5, 356559-13-2 (HCl) | 10 mM | S2186 | TGF-beta/[NAME] | SB505124 is a selective inhibitor of ALK4 and ALK5 with IC50 of 129 nM and 47 nM, respectively.
SB590885 | e1-L1700-11 | 405554-55-4 | 10 mM | S2220 | Raf | SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM.
Palomid 529 | e2-L1700-11 | 914913-88-5 | 10 mM | S2238 | PI3K | Palomid 529 (P529) is a PI3K/Akt/mTOR inhibitor for VEGF-A and bFGF with IC50 of 10 nM and 30 nM, respectively.
20-Hydroxyecdysone | e3-L1700-11 | 5289-74-7 | 10 mM | S2417 |  | 20-Hydroxyecdysone (Ecdysterone, 20E) is a naturally occurring ecdysteroid hormone which controls the ecdysis (moulting) and metamorphosis of arthropods.
Aloperine | e4-L1700-11 | 56293-29-9 | 10 mM | S2420 |  | Aloperine is exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.
Synephrine HCl | e5-L1700-11 | 5985-28-4 | 10 mM | S2438 | Adrenergic Receptor | Synephrine HCl (Oxedrine, p-Synephrine) is a sympathomimetic α-adrenergic receptor (AR) agonist.
Forskolin | e6-L1700-11 | 66575-29-9 | 10 mM | S2449 | cAMP | [NAME] is a ubiquitous activator of eukaryotic adenylyl cyclase (AC).
Equol | e7-L1700-11 | 531-95-3, 1112376-13-2 (H2SO4) | 10 mM | S2450 | Estrogen/progestogen Receptor | Equol is an isoflavandiol metabolized from daidzein by bacterial flora in the intestines.
Daphnetin | e8-L1700-11 | 486-35-1 | 10 mM | S2554 | DNA/RNA Synthesis | Daphnetin is an inhibitor of EGFR, PKA and PKC with IC50 of 7.67 μM, 9.33 μM and 25.01 μM, respectively.
[NAME] (Adonitol) | e9-L1700-11 | 488-81-3 | 10 mM | S2612 |  | [NAME] (Adonitol) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.
R788 (Fostamatinib) | e10-L1700-11 | 901119-35-5 | 10 mM | S2625 | Syk | R788 (Fostamatinib) is a Syk inhibitor with IC50 of 41 nM.
A 922500 | e11-L1700-11 | 959122-11-3 | 10 mM | S2674 | Transferase | A 922500 is a DGAT-1 inhibitor for human and [NAME] with IC50 of 7 nM and 24 nM, respectively.
CAY10505 | f1-L1700-11 | 1218777-13-9 | 10 mM | S2682 | PI3K | CAY10505 is a PI3Kγ inhibitor with IC50 of 30 nM.
CHIR-124 | f2-L1700-11 | 405168-58-3 | 10 mM | S2683 | Chk | CHIR-124 is a novel and potent Chk1 inhibitor with IC50 of 0.3 nM.
CX-5461 | f3-L1700-11 | 1138549-36-6 | 10 mM | S2684 | DNA/RNA Synthesis | CX-5461 selectively inhibits [NAME] I-driven transcription of rRNA with IC50 of 142 nM in HCT-116 cells.
[NAME] | f4-L1700-11 | 819812-04-9, 819812-18-5 (HCl) | 10 mM | S2685 | HSP (e.g. [NAME]) | [NAME] is a nonansamycin HSP90 inhibitor with IC50 of 3.8 nM.
PF-2545920 | f5-L1700-11 | 1292799-56-4 | 10 mM | S2687 | PDE | PF-2545920 is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM.
Nepicastat HCl | f6-L1700-11 | 170151-24-3, 173997-05-2 (free base), 177645-08-8 ( HCl.H2O) | 10 mM | S2695 | Hydroxylase | Nepicastat hydrochloride is a novel, potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.
LY2109761 | f7-L1700-11 | 700874-71-1 | 10 mM | S2704 | TGF-beta/[NAME] | LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with [NAME] of 38 nM and 300 nM, respectively.
[NAME] | f8-L1700-11 | 244218-51-7, 244218-93-7 (free base) | 10 mM | S2722 | Opioid Receptor | JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM.
PF-03814735 | f9-L1700-11 | 942487-16-3 | 10 mM | S2725 | [NAME] | PF-03814735 is a novel, potent and reversible inhibitor of both [NAME] and [NAME] B with IC50 of 0.8 nM and 5 nM, respectively.
Dacomitinib (PF299804,PF-00299804) | f10-L1700-11 | 1110813-31-4, 1042385-75-0 (H2O) | 10 mM | S2727 | EGFR | PF299804 is a potent, irreversible pan-ErbB inhibitor against ErbB1, ErbB2 and ErbB4 with IC50 of 6 nM, 45.7 nM and 73.7 nM, respectively.
AG-1478 (Tyrphostin AG-1478) | f11-L1700-11 | 153436-53-4, 170449-18-0 (HCl) | 10 mM | S2728 | EGFR | AG-1478 (Tyrphostin AG-1478) is a selective EGFR inhibitor with IC50 of 3 nM.
SB 415286 | g1-L1700-11 | 264218-23-7 | 10 mM | S2729 | GSK-3 | SB 415286 is a potent GSK3α and GSK3β inhibitor with IC50 of 78 nM and ~78 nM, respectively.
AZ 3146 | g2-L1700-11 | 1124329-14-1 | 10 mM | S2731 | Kinesin | AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.
SCH 900776 | g3-L1700-11 | 891494-63-6 | 10 mM | S2735 | Chk | SCH 900776 is a selective Chk1 inhibitor with IC50 of 3 nM and also inhibits CDK2 with IC50 of 160 nM.
TG101348 (SAR302503) | g4-L1700-11 | 936091-26-8, 1374744-69-0 (2ClH.H2O) | 10 mM | S2736 | JAK | [NAME] ([NAME]) is a selective inhibitor of JAK2 with IC50 of 3 nM.
PAC-1 | g5-L1700-11 | 315183-21-2 | 10 mM | S2738 | Caspase | PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM.
PKI-402 | g6-L1700-11 | 1173204-81-3, 1173204-82-4 (XHCl) | 10 mM | S2739 | PI3K | PKI-402 is a potent dual PI3K/mTOR inhibitor targeting PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ and mTOR with IC50 of 2 nM, 7 nM, 16 nM, 14 nM, and 3 nM, respectively.
GSK1070916 | g7-L1700-11 | 942918-07-2 | 10 mM | S2740 | [NAME] | GSK1070916 is a reversible and ATP-competitive inhibitor of [NAME] and [NAME] with IC50 of 3.5 nM and 6.5 nM, respectively.
PHA-767491 | g8-L1700-11 | 845714-00-3, 942425-68-5 (HCl) | 10 mM | S2742 | CDK | PHA-767491 is a potent ATP-competitive dual Cdc7/[NAME] inhibitor with IC50 of 10 nM and 34 nM, respectively.
CCT137690 | g9-L1700-11 | 1095382-05-0 | 10 mM | S2744 | [NAME] | CCT137690 is a highly selective inhibitor of [NAME], [NAME] and [NAME] with IC50 of 15 nM, 25 nM and 19 nM, respectively.
CHIR-98014 | g10-L1700-11 | 252935-94-7 | 10 mM | S2745 | GSK-3 | CHIR-98014 is a potent and selective GSK-3 inhibitor for GSK-3ɑ and GSK-3β with IC50 of 0.65 nM and 0.58 nM, respectively.
AZ628 | g11-L1700-11 | 878739-06-1 | 10 mM | S2746 | Raf | AZ628 is a potent inhibitor for wild-type CRAF and BRAFV600E with IC50 of 29 nM and 34 nM, respectively.
AMG458 | h1-L1700-11 | 913376-83-7 | 10 mM | S2747 | c-Met | AMG 458 is a potent c-Met inhibitor of human c-Met and mouse c-Met with Ki of 1.2 nM or 2.0 nM.
Anacetrapib (MK-0859) | h2-L1700-11 | 875446-37-0 | 10 mM | S2748 | CETP | Anacetrapib (MK0859) is a potent and selective rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, respectively
NVP-BGT226 | h3-L1700-11 | 1245537-68-1, 915020-55-2 (free base) | 10 mM | S2749 | PI3K | NVP-BGT226 is a novel dual PI3K/mTOR inhibitor with IC50 of 1 nM.
GW788388 | h4-L1700-11 | 452342-67-5, 1353867-76-1 (H2O) | 10 mM | S2750 | TGF-beta/[NAME] | GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM.
PHA-848125 | h5-L1700-11 | 802539-81-7, 802540-32-5 (3HCl), 1253645-38-3 (Maleic acid) | 10 mM | S2751 | CDK | PHA-848125 is a potent, ATP-competitive cyclin A/CDK2 inhibitor with IC50 of 45 nM.
Arry-380 | h6-L1700-11 | 937265-83-3 | 10 mM | S2752 | HER2 | ARRY-380 is a potent and selective HER2 inhibitor with IC50 of 8 nM and also inhibits EGFR with IC50 of 4 μM.
ARQ 197 (Tivantinib) | h7-L1700-11 | 905854-02-6, 1000873-98-2, 1228508-24-4 | 10 mM | S2753 | c-Met | ARQ-197 is a novel and selective human c-Met inhibitor with IC50 of 0.1 μM.
AT-406 | h8-L1700-11 | 1071992-99-8, 1071992-57-8 (HCl) | 10 mM | S2754 | IAP | AT-406 is a potent IAP (inhibitor of apoptosis protein) inhibitor of XIAP, cIAP1, and [NAME] with [NAME] of 66.4 nM, 1.9 nM, and 5.1 nM, respectively.
ARRY334543 | h9-L1700-11 | 845272-21-1, 1146629-86-8 (di4-methylbenzenesulfonate) | 10 mM | S2755 | EGFR | ARRY334543 is a selective and potent ErbB1 and ErbB2 inhibitor with IC50 of 7 nM and 2 nM, respectively.
Wortmannin | h10-L1700-11 | 19545-26-7, 1405-03-4 | 10 mM | S2758 | PI3K | Wortmannin is a multi-target inhibitor of MLCK and [NAME] with IC50 of 0.17 μM and 3 nM, respectively.
PI3K/HDAC Inhibitor I | h11-L1700-11 | 1339928-25-4 | 10 mM | S2759 | HDAC | PI3K/HDAC Inhibitor I is a dual PI3K and HDAC inhibitor for PI3Kɑ, HDAC1, HDAC2, HDAC3 and HDAC10 with IC50 of 19 nM, 1.7 nM, 5 nM, 1.8 nM and 2.8 nM, respectively.
Canagliflozin | a1-L1700-12 | 842133-18-0, 928672-86-0 (0.5H2O) | 10 mM | S2760 | SGLT | Canagliflozin is a highly potent and selective SGLT2 inhibitor for CHO-hSGLT2, CHO-rSGLT2 and CHO-mSGLT2 with IC50 of 4.4 nM, 3.7 nM and 2 nM, respectively.
NVP-BVU972 | a2-L1700-12 | 1185763-69-2 | 10 mM | S2761 | c-Met | NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.
CH5424802 | a3-L1700-12 | 1256580-46-7, 1256589-74-8 (HCl) | 10 mM | S2762 | ALK | CH5424802 is a potent and selective ALK inhibitor with IC50 of 1.9 nM.
MK-2048 | a4-L1700-12 | 869901-69-9 | 10 mM | S2765 | Integrase | [NAME] is an potent inhibitor of integrase (IN) and [NAME] with IC50 of 2.6 nM and 1.5 nM, respectively.
3-Methyladenine | a5-L1700-12 | 5142-23-4, 80681-18-1(HCl) | 10 mM | S2767 | PI3K | 3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM, respectively.
Dinaciclib (SCH727965) | a6-L1700-12 | 779353-01-4 | 10 mM | S2768 | CDK | Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, [NAME] and [NAME] with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively.
Dovitinib Dilactic acid (TKI258 Dilactic acid) | a7-L1700-12 | 852433-84-2, 405169-16-6 (free base) | 10 mM | S2769 | FLT3 | [NAME] (TKI258, CHIR-258) is a multitargeted tyrosine kinase inhibitor of FLT3 and c-KIT with IC50 of 1 nM and 2 nM, respectively.
MK-5108 (VX-689) | a8-L1700-12 | 1010085-13-8 | 10 mM | S2770 | [NAME] | MK-5108 (VX-689) is a highly selective [NAME] A inhibitor with IC50 of 0.064 nM.
Dalcetrapib (JTT-705) | a9-L1700-12 | 211513-37-0 | 10 mM | S2772 | CETP | Dalcetrapib (JTT-705) is a rhCETP inhibitor with IC50 of 0.2 μM.
SB705498 | a10-L1700-12 | 501951-42-4 | 10 mM | S2773 | TRPV | SB705498 is a TRPV1 antagonist for [NAME] with pIC50 and pKi of 7.1 and 7.6 in HEK293 cells.
MK-2461 | a11-L1700-12 | 917879-39-1, 1196681-15-8, 1170702-87-0 (sodium salt) | 10 mM | S2774 | c-Met | MK-2461 is a potent inhibitor of c-Met, [NAME], Flt1/3, PDGFRβ, [NAME] and FGFR1/2/3 with IC50 of 2.5 nM, 7 nM, 10 nM/22 nM, 22 nM, 24 nM and 65 nM/39 nM/50 nM, respectively.
Nocodazole | b1-L1700-12 | 31430-18-9, 61167-17-7 (HCl) | 10 mM | S2775 | [NAME] | Nocodazole inhibits Abl, [NAME]) and [NAME]) with IC50 of 0.21 μM, 0.53 μM and 0.64 μM, respectively.
CPI-613 | b2-L1700-12 | 95809-78-2 | 10 mM | S2776 | Dehydrogenase | CPI-613 inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase.
PF-5274857 | b3-L1700-12 | 1373615-35-0 | 10 mM | S2777 | Smoothened | PF-5274857 is a potent and selective Smoothened ([NAME]) antagonist with IC50 and [NAME] of 5.8 nM and 4.6 nM, respectively.
GW842166X | b4-L1700-12 | 666260-75-9, 956013-38-0 | 10 mM | S2778 | Cannabinoid Receptor | GW842166X is a potent and highly selective agonist of CB2 receptor.
M344 | [NAME] | 251456-60-7 | 10 mM | S2779 | HDAC | M344 is a potent HDAC inhibitor with IC50 of 100 nM.
GW4064 | b6-L1700-12 | 278779-30-9 | 10 mM | S2782 | FXR | GW 4064 is an agonist of farnesoid X receptor (FXR) with EC50 of 65 nM.
AZD2014 | b7-L1700-12 | 1009298-59-2 | 10 mM | S2783 | mTOR | AZD2014 is a novel dual mTORC1 and mTORC2 inhibitor with potential antineoplastic activity.
TAK-285 | b8-L1700-12 | 871026-44-7, 871027-78-0 (methanesulfonate) | 10 mM | S2784 | EGFR | TAK-285 is a novel dual [NAME] and EGFR inhibitor with IC50 of 17 nM and 23 nM, respectively.
A-803467 | b9-L1700-12 | 944261-79-4 | 10 mM | S2785 | Sodium Channel | A-803467 is a selective NaV1.8 channel blocker with IC50 of 8 nM.
Laquinimod (ABR-215062) | b10-L1700-12 | 248281-84-7, 248282-07-7 (sodium salt) | 10 mM | S2787 |  | Laquinimod (ABR-215062) is a potent immunomodulator.
INCB28060 | b11-L1700-12 | 1029712-80-8, 1029714-89-3 (XHCl), 1197376-85-4 (2HCl) | 10 mM | S2788 | c-Met | INCB28060 is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM.
[NAME] (CP-690550, Tasocitinib) | c1-L1700-12 | 477600-75-2, 540737-29-9 (citrate) | 10 mM | S2789 | JAK | CP-690550 is a novel inhibitor of JAK3 with IC50 of 1 nM.
[NAME] (KW-6002) | c2-L1700-12 | 155270-99-8, 861889-00-1 (6H2O), 861889-02-3 (5H2O) | 10 mM | S2790 |  | [NAME] (KW-6002) is a selective adenosine A2A receptor (A2AR) antagonist with [NAME] of 2.2 nM.
[NAME] (AEB071) | c3-L1700-12 | 425637-18-9, 1058706-32-3 (HCl), 1058706-35-6 (Maleic acid) | 10 mM | S2791 | PKC | [NAME] (AEB071) is a potent selective pan-PKC inhibitor and highly inhibits PKCθ with Ki of 0.22 nM.
Torcetrapib (CP-529414) | c4-L1700-12 | 262352-17-0 | 10 mM | S2792 | CETP | Torcetrapib (CP-529414) is a CETP inhibitor with IC50 of 37 nM.
VU 0357121 | c5-L1700-12 | 433967-28-3 | 10 mM | S2795 | GluR | VU0357121 is a novel allosteric modulator of mGlu5 with EC50 of 33 nM.
WP1066 | c6-L1700-12 | 857064-38-1 | 10 mM | S2796 | JAK | WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells .
Lonafarnib (SCH66336) | c7-L1700-12 | 193275-84-2 | 10 mM | S2797 | Transferase | Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.
AZD4547 | c8-L1700-12 | 1035270-39-3 | 10 mM | S2801 | FGFR | AZD4547 is a novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3 with IC50 of of 0.2 nM, 2.5 nM, and 1.8 nM, respectively.
BAY80-6946 | c9-L1700-12 | 1032568-63-0 | 10 mM | S2802 | PI3K
Galeterone (TOK-001) | c10-L1700-12 | 851983-85-2, 1239339-16-2 (methanesulfonate), 1239339-18-4 (sulfate), 1239339-17-3 (HCl) | 10 mM | S2803 | Androgen Receptor | Galeterone (TOK-001, VN/124-1) is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively.
Sirtinol | c11-L1700-12 | 410536-97-9 | 10 mM | S2804 | Sirtuin | [NAME] is a specific SIRT1 and SIRT2 inhibtor with IC50 of 131 μM and 38 μM, respectively.
LY364947 | d1-L1700-12 | 396129-53-6 | 10 mM | S2805 | TGF-beta/[NAME] | LY364947 is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM.
CEP33779 | d2-L1700-12 | 1257704-57-6 | 10 mM | S2806 | JAK | CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM.
[NAME] (GSK2118436) | d3-L1700-12 | 1195765-45-7, 1195768-06-9 (methanesulfonic acid) | 10 mM | S2807 | Raf | [NAME] (GSK2118436) is a potent ATP-competitive inhibitor of B-Raf, B-RafV600E and c-Raf with IC50 of 3.2 nM, 0.8 nM and 5.0 nM, respectively.
GDC-0068 | d4-L1700-12 | 1001264-89-6 | 10 mM | S2808 | [NAME] | GDC-0068 is a highly selective pan-Akt inhibitor targeting Akt1, Akt2 and Akt3 with IC50 of 5 nM, 18 nM and 8 nM, respectively.
MPEP | d5-L1700-12 | 96206-92-7, 219911-35-0 (HCl) | 10 mM | S2809 | GluR | MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM.
INK 128 | d6-L1700-12 | 1224844-38-5 | 10 mM | S2811 | mTOR | INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM.
Ciproxifan | d7-L1700-12 | 184025-19-2, 184025018-1(free base) | 10 mM | S2813 | Histamine Receptor | Ciproxifan is a highly potent and selective H3-receptor antagonist with IC50 of 9.2 nM.
BYL719 | d8-L1700-12 | 1217486-61-7 | 10 mM | S2814 | PI3K | BYL719 strongly and selectively inhibits the PI3Kα.
Tyrphostin AG 879 (AG 879) | d9-L1700-12 | 148741-30-4 | 10 mM | S2816 | HER2 | AG879 inhibits both ErbB2 and Flk-1 with IC50 of 1 μM.
Torin 2 | d10-L1700-12 | 1223001-51-1 | 10 mM | S2817 | mTOR | Torin2 is a highly potent and selective mTOR inhibitor with IC50 of 0.25 nM.
CI994 (Tacedinaline) | d11-L1700-12 | 112522-64-2, 1299346-14-7 (HCl), 1353653-79-8 (TFA) | 10 mM | [NAME] | HDAC | CI994 (Tacedinaline) is an anti-cancer drug which inhibits HDAC1 with IC50 of 0.57 [NAME]
[NAME] | e1-L1700-12 | 183232-66-8, 1061340-04-2 (TFA) | 10 mM | S2819 | Cannabinoid Receptor | AM251 is a cannabinoid 1 receptor antagonist with IC50 of 8.9 μM.
NVP-TAE226 | e2-L1700-12 | 761437-28-9 | 10 mM | S2820 | FAK | NVP-TAE226, a potent dual FAK/IGF-IR, inhibiting FAK and IGF-IR with IC50 of 5.5 nM and 0.14 μM, respectively.
RG108 | e3-L1700-12 | 48208-26-0 | 10 mM | S2821 | Transferase | RG108 is an inhibitor of DNA methyltransferase with IC50 of 115 nM.
Tideglusib | e4-L1700-12 | 865854-05-3 | 10 mM | S2823 | GSK-3 | Tideglusib (NP031112, NP-12) is a potent non ATP-competitive inhibitor of [NAME] with IC50 of 60 nM.
TPCA-1 | e5-L1700-12 | 507475-17-4 | 10 mM | S2824 | IKK | TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM.
ML133 HCl | e6-L1700-12 | 1222781-70-5, 185669-79-8 (free base) | 10 mM | S2825 | Potassium Channel | ML133 is a potent potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5).
Desmethyl Erlotinib (CP-473420) | e7-L1700-12 | 183321-86-0, 183320-51-6 (HCl) | 10 mM | S2826 | EGFR | Desmethyl Erlotinib (CP-473420) is a free base of OSI-420, which is an active metabolite of Erlotinib which is an orally active EGFR inhibitor for human EGFR with IC50 of 2 nM.
Torin 1 | e8-L1700-12 | 1222998-36-8 | 10 mM | S2827 | mTOR | Torin1 is a potent inhibitor of mTOR with IC50 of 2-10 nM.
JNJ 1661010 | e9-L1700-12 | 681136-29-8 | 10 mM | S2828 | FAAH | [NAME] is a potent and selective FAAH inhibitor with IC50 of 10 nM (rat) and 12 nM (human).
Epiandrosterone (3β-androsterone) | e10-L1700-12 | 481-29-8 | 10 mM | S2832 | Estrogen/progestogen Receptor
ARN-509 | e11-L1700-12 | 956104-40-8 | 10 mM | S2840 | Adrenergic Receptor | ARN-509 is a selective androgen receptor inhibitor with IC50 of 16 nM.
R428 | f1-L1700-12 | 1037624-75-1 | 10 mM | S2841 |  | R428 is an inhibitor of Axl with IC50 of 14 nM.
SAR131675 | f2-L1700-12 |  | 10 mM | S2842 | VEGFR | SAR131675 is a VEGFR-3 inhibitor with IC50 of 20 nM.
BI-D1870 | f3-L1700-12 | 501437-28-1 | 10 mM | S2843 | [NAME] | BI-D1870 is an ATP-competitive inhibitor of ribosomal S6 for RSK1, RSK2, [NAME] and [NAME] with IC50 of 31 nM, 24 nM, 18 nM and 15 nM, respectively.
Semaxanib (SU5416) | f4-L1700-12 | 194413-58-6 | 10 mM | S2845 | VEGFR | Adrenalone is an adrenergic agonist.
Cathepsin Inhibitor 1 | f5-L1700-12 | 225120-65-0 | 10 mM | S2847 |  | Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.
[NAME] | f6-L1700-12 | 261901-57-9, 201038-74-6 (free base) | 10 mM | [NAME] | 5-HT Receptor | [NAME] is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3.
Baricitinib (LY3009104) | f7-L1700-12 | 1187594-09-7, 1187594-10-0 (TFA) | 10 mM | S2851 | JAK | Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, respectively.
BRL 54443 | f8-L1700-12 | 57477-39-1, 57477-41-5 (HBr), 1197333-54-2 (Maleic acid) | 10 mM | S2852 | 5-HT Receptor | BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively.
Carfilzomib (PR-171) | f9-L1700-12 | 868540-17-4, 1140908-84-4 (TFA), 1140908-85-5 (methanesulfonate) | 10 mM | S2853 | Proteasome | Carfilzomib (PR-171) is a proteasome inhibitor with IC50 less than 5 nM.
BML-190 | f10-L1700-12 | 2854-32-2 | 10 mM | S2854 | Cannabinoid Receptor | BML-190 is a selective CB2 inverse agonist with Ki of 435 nM.
MRS 2578 | f11-L1700-12 | 711019-86-2 | 10 mM | S2855 | [NAME] | MRS2578 is a potent P2Y6 receptor with IC50 of 37 nM.
SB 271046 | g1-L1700-12 | 209481-20-9 | 10 mM | S2856 | 5-HT Receptor | SB-271046 is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9.
Dizocilpine (MK 801) | g2-L1700-12 | 77086-21-6 | 10 mM | S2857 | GluR | Dizocilpine is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with [NAME] of 30.5 nM.
StemRegenin 1 | g3-L1700-12 | 1227633-49-9 | 10 mM | S2858 |  | StemRegenin 1 is an AhR inhibitor with IC50 of 127 nM.
Golvatinib (E7050) | g4-L1700-12 | 928037-13-2 , 1007601-96-8 (L(+)-Tartaric Acid), 1007601-91-3 (Fumaric acid) | 10 mM | S2859 | c-Met | E7050 is a dual c-Met and VEGFR-2 inhibitor with IC50 of 14 nM and 16 nM, respectively.
IEM 1754 dihydrobroMide | g5-L1700-12 | 162831-31-4, 697221-65-1 (free base) | 10 mM | S2860 | GluR | IEM 1754 dihydrobroMide  is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
CTEP | g6-L1700-12 | 871362-31-1 | 10 mM | S2861 | GluR | CTEP is a selective allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM.
VU 0364770 | g7-L1700-12 | 61350-00-3 | 10 mM | S2862 | GluR | VU 0364770 is a selective positive allosteric mGlu4 with EC50 of 1.1 μM.
ML130 | g8-L1700-12 | 799264-47-4 | 10 mM | S2863 | NOD1 | ML130 is a potent and selective inhibitor of NOD1 with IC50 of 0.56 [NAME]
IMD 0354 | g9-L1700-12 | 978-62-1, 634914-41-3 (sodium salt ) | 10 mM | S2864 | IKK | IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NFκβ pathway.
VUF 10166 | g10-L1700-12 | 155584-74-0, 55686-37-8 (HCl) | 10 mM | S2865 | 5-HT Receptor | VUF10166 is a novel, potent and competitive antagonist to 5-HT3A with [NAME] of 0.04 nM.
U-104 | g11-L1700-12 | 178606-66-1 | 10 mM | S2866 | Carbonic Anhydrase | U-104 is a potent carbonic anhydrase (CA) inhibitor for CA IX and CA XII with IC50 of 45.1 nM and 4.5 nM, respectively.
WHI-P154 | h1-L1700-12 | 211555-04-3, 296234-84-9 (HCl) | 10 mM | S2867 | JAK | WHI-P154 is a potent [NAME] inhibitor with IC50 of 1.8 μM and also inhibits EGFR with IC50 of 4 nM.
Alogliptin (SYR-322) | h2-L1700-12 | 850649-61-5, 850649-62-6 (benzoate) | 10 mM | S2868 | DPP-4 | [NAME]) is a potent, selective inhibitor of DPP-4 with IC50 of < 10 nM.
TG 100713 | h3-L1700-12 | 925705-73-3 | 10 mM | S2870 | PI3K | TG 100713 is a PI3K inhibitor for PI3Kg, PI3Kd, PI3Ka and PI3Kb with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.
T0070907 | h4-L1700-12 | 313516-66-4, 372095-17-5 (HCl) | 10 mM | S2871 | PPAR | T0070907 is a potent and selective PPARγ inhibitor with IC50 of 1 nM.
Camostat Mesilate (FOY-305) | h5-L1700-12 | 59721-29-8 | 10 mM | S2874 | HCV Protease | Camostat is a trypsin-like protease inhibitor, inhibiting matriptase and human neutrophil elastase with IC50 of 0.5 μM and 0.2 μM, respectively.
Prucalopride | h6-L1700-12 | 179474-81-8, 179474-80-7 (HCl) | 10 mM | S2875 | 5-HT Receptor | Prucalopride is a potent 5-HT4 receptor antagonist with IC50 of 2.5 nM.
(-)-MK 801 Maleate | h7-L1700-12 | 121917-57-5 | 10 mM | S2876 | GluR | MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
L-NAME HCl | h8-L1700-12 | 51298-62-5, 50903-99-6 (free base) | 10 mM | S2877 |  | L-NAME is a nonselective inhibitor of nitric oxide synthetases (NOS) for nNOS (bovine), eNOS (human), and iNOS (murine), with [NAME] of 15 nM, 39 nM and 4.4 μM, respectively.
[NAME] | h9-L1700-12 | 873225-46-8 | 10 mM | S2882 | IKK | IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
Rivaroxaban (Xarelto) | h10-L1700-12 | 366789-02-8, 931385-22-7 (XHCl) | 10 mM | S3002 | Factor Xa | Rivaroxaban (Xarelto) is a FXa inhibitor, showed a similar affinity to purified human and rabbit FXa (IC50 0.7 ± 0.01 and 0.8 ± 0.01 nM).
Sitagliptin phosphate monohydrate | h11-L1700-12 | 654671-77-9, 486460-32-6 (free base), 654671-78-0 (phosphate) | 10 mM | S4002 | DPP-4 | Sitagliptin phosphate monohydrate is a Dipeptidyl Peptidase-IV Inhibitor.
A 205804 | a1-L1700-13 | 251992-66-2 | 10 mM | S2885 |  | A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.
PF-562271 | a2-L1700-13 | 717907-75-0 | 10 mM | S2890 | FAK | PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK and [NAME] with IC50 of 1.5 nM and 14 nM, respectively.
GW441756 | a3-L1700-13 | 504433-23-2 | 10 mM | S2891
VU 0361737 | a4-L1700-13 | 1161205-04-4 | 10 mM | S2892 | GluR
NU7026 | a5-L1700-13 | 154447-35-5 | 10 mM | S2893 | DNA-PK | NU7026 is a DNA-PK inhibitor with IC50 of 0.23 μM.
SB-742457 | a6-L1700-13 | 607742-69-8 | 10 mM | S2894 | 5-HT Receptor | SB-742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63.
Tyrphostin 9 (SF 6847) | a7-L1700-13 | 10537-47-0 | 10 mM | S2895 | EGFR | SF 6847 is an inhibitor of EGFR with IC50 of 460 μM.
ZM 323881 HCl | a8-L1700-13 | 193000-39-4 | 10 mM | S2896 | VEGFR | ZM-323881 is a potent and selective inhibitor of VEGFR2 with IC50 < 2 nM.
ZM 306416 | a9-L1700-13 | 690206-97-4 | 10 mM | S2897 | VEGFR | ZM-306416 is a VEGFR inhibitor, inhibiting [NAME], [NAME] and Abl with IC50 of 0.33 μM, 0.33 μM and 1.3 μM, respectively.
CCG 50014 | a10-L1700-13 | 883050-24-6 | 10 mM | S2901 |  | CCG 50014 is a potent and selective inhibitor of [NAME] with IC50 of 30 nM.
S-Ruxolitinib | a11-L1700-13 | 941685-37-6 | 10 mM | S2902 | JAK | S-Ruxolitinib is a JAK family inhibitor for [NAME] and JAK2 with IC50 of 3.3 nM and 2.8 nM, respectively.
Lumiracoxib (COX-189) | b1-L1700-13 | 220991-20-8 | 10 mM | S2903 | COX | Lumiracoxib (COX-189) is a novel, selective COX-2 inhibitor with [NAME] of 0.06 [NAME]
PF 477736 | b2-L1700-13 | 952021-60-2 | 10 mM | S2904 | Chk | PF 477736 is a ChK inhibitor against ChK1, ChK2, VEGFR2, Yes and Fms with IC50 of 0.49 nM, 47 nM, 8 nM, 14 nM and 10 nM, respectively.
JNJ-7777120 | b3-L1700-13 | 459168-41-3 | 10 mM | S2905 | Histamine Receptor | JNJ-7777120 is a potent and selective non-imidazole histamine H4 receptor antagonist with Ki of 4.5 nM.
Ki16198 | b4-L1700-13 | 355025-13-7 | 10 mM | S2906 | LPA Receptor
Pirfenidone | [NAME] | 53179-13-8 | 10 mM | S2907 | TGF-beta/[NAME] | Pirfenidone inhibits TGF-β bioactivity by affecting TGF-β2 mRNA expression and processing of pro-TGF-β in CCL-64 cells.
Tempol (4-Hydroxy-TEMPO) | b6-L1700-13 | 2226-96-2 | 10 mM | S2910
Go 6983 | b7-L1700-13 | 133053-19-7 | 10 mM | S2911 | PKC | Go 6983 is a pan PKC inhibitor against PKCα, PKCβ, PKCγ, PKCδ, PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively.
WZ 811 | b8-L1700-13 | 55778-02-4 | 10 mM | S2912 | CXCR | WZ811 is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM.
Dapivirine | b9-L1700-13 | 244767-67-7 | 10 mM | S2914 | Reverse Transcriptase | Dapivirine is an nonnucleoside reverse transcriptase inhibitor for HIV reverse transcriptase with IC50 of 24 nM.
GW9662 | b10-L1700-13 | 22978-25-2 | 10 mM | S2915 | PPAR | GW9662 is a selective PPAR antagonist, inhibiting PPARγ, PPARα and PPARδ with IC50 of 3.3 nM, 32 nM and 2 μM, respectively.
ML-161 | b11-L1700-13 | 423735-93-7 | 10 mM | S2916 |  | ML-161 is an allosteric inhibitor of PAR1 with IC50 of 0.26 [NAME]
SA 4503 | c1-L1700-13 | 165377-44-6, 165377-43-5 (free base) | 10 mM | S2917 | Opioid Receptor | SA 4503 is a novel and selective opioid sigma1 receptor agonist with IC50 of 17.4 nM.
HC-030031 | c2-L1700-13 | 349085-38-7 | 10 mM | S2918 |  | HC-030031 is a selective TRPA1 channel blocker that antagonizes AITC- and formalin-evoked calcium influx with IC50 of 6.2 μM and 5.3 μM respectively.
IOX2 | c3-L1700-13 | 931398-72-0 | 10 mM | S2919 | HIF | IOX2 is a potent inhibitor of HIF-1α prolyl [NAME] (PHD2) with IC50 of 21 nM.
Mozavaptan | c4-L1700-13 | 137975-06-5, 138470-70-9 (HCl) | 10 mM | S2920
Icotinib | c5-L1700-13 | 610798-31-7 | 10 mM | [NAME] | EGFR
Salubrinal | c6-L1700-13 | 405060-95-9 | 10 mM | S2923 |  | Salubrinal is a selective inhibitor of eIF2α dephosphorylation and inhibits ER stress-mediated apoptosis with EC50 of ~15 μM.
CHIR-99021 (CT99021) HCl | c7-L1700-13 | 252917-06-9 (free base) | 10 mM | S2924 | GSK-3 | CHIR-99021 HCl (CT99021) is hydrochloride of CHIR-99021, which is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively.
TDZD-8 | c8-L1700-13 | 327036-89-5 | 10 mM | S2926 | GSK-3
TAK 715 | c9-L1700-13 | 303162-79-0 | 10 mM | S2928 | p38 MAPK
[NAME] | c10-L1700-13 | 10083-24-6, 21100-92-5 | 10 mM | S3026 | Syk | Piceatannol is a selective Syk inhibitor with IC50 of ~10 μM.
Sitaxentan sodium (TBC-11251) | c11-L1700-13 | 210421-74-2, 184036-34-8 (free base) | 10 mM | S3034 | Endothelin Receptor | Sitaxentan sodium (TBC-11251) is a selective endothelin receptor-A antagonist with IC50 and [NAME] of 1.4 nM and 0.43 nM, respectively.
Purmorphamine | d1-L1700-13 | 483367-10-8 | 10 mM | S3042 | Smoothened | Purmorphamine directly binds and activates Smoothened with IC50 of ~ 1.5 μM in compete with [NAME] antagonist and also is a inducer of osteoblast differentiation with EC50 of 1μM.
Bosentan Hydrate | d2-L1700-13 | 157212-55-0, 147536-97-8 (free base), 150726-52-6 (sodium salt ) | 10 mM | S3051 | Endothelin Receptor | Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.
Rupatadine Fumarate | d3-L1700-13 | 182349-12-8 | 10 mM | S3052 | Histamine Receptor | Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with [NAME] of 550 and 102 nM, respectively.
VX-702 | d4-L1700-13 | 745833-23-2, 479543-46-9 | 10 mM | S6005 | p38 MAPK | VX-702 is a highly selective inhibitor of p38 MAPKα with IC50 of 4-20 nM.
Ambroxol HCl | d5-L1700-13 | 23828-92-4 | 10 mM | [NAME] | Sodium Channel | Ambroxol HCl is a potent inhibitor of the neuronal Na+ channels with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, respectively.
Piracetam | d6-L1700-13 | 7491-74-9 | 10 mM | S3070 |  | Piracetam is a cyclic derivative of the neurotransmitter ?-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.
Naringenin | d7-L1700-13 | 480-41-1 | 10 mM | S2394 | P450 (e.g. CYP17) | Naringenin is a flavonoid that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator.
Fingolimod (FTY720) | d8-L1700-13 | 162359-56-0, 162359-55-9 (free base), 1227170-83-3 (acetate) | 10 mM | S5002 | S1P Receptor | FTY720 (Fingolimod, Gilenya) is a S1P antagonist with IC50 of 0.033 nM.
LY2140023 (LY404039) | d9-L1700-13 | 635318-55-7, 956385-05-0 (H2O),635318-26-2 (HCl) | 10 mM | S6001 | GluR | LY404039 is a potent agonist of recombinant human mGlu2, mGlu3 receptors and rat neurons expressing native mGlu2/3 receptors with [NAME] of 149 nM, 92 nM and 88 nM, respectively.
NXY-059 (Cerovive) | d10-L1700-13 | 168021-79-2, 252027-72-8, 168021-77-0 (free base) | 10 mM | S6002 |  | NXY-059 (Cerovive) is a novel nitrone, shows efficacious neuroprotective effects.
PTC124 ([NAME]) | d11-L1700-13 | 775304-57-9, 1015238-98-8 (H2O), 775304-59-1 (sodium salt) | 10 mM | S6003 | CFTR | [NAME] ([NAME]) is a potent nonsense mutation inhibitor with EC50 of ~0.1 [NAME]
Malotilate | e1-L1700-13 | 59937-28-9 | 10 mM | S1137 |  | Malotilate is a liver protein metabolism improved compound.
Melatonin | e2-L1700-13 | 73-31-4 | 10 mM | S1204 |  | Melatonin is a hormone produced in the brain by the pineal gland from the amino acid tryptophan.
Abitrexate (Methotrexate) | e3-L1700-13 | 59-05-2 | 10 mM | S1210 | DHFR | Abitrexate(Methotrexate) is an antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities.
Clafen (Cyclophosphamide) | e4-L1700-13 | 50-18-0, 60007-95-6, 75526-90-8 | 10 mM | S1217 | DNA/RNA Synthesis | This agent inhibited cell proliferation of NCI-H727 with IC50 at 9.3 nM.
Vinblastine | e5-L1700-13 | 57-22-7 | 10 mM | S1248 | AChR | Inhibits microtubule formation and nicotinic acetylcholine receptor (nAChR) activity .In cultured chromaffin cells, vinblastine (IC50=8.9 microM).
Dienogest | e6-L1700-13 | 65928-58-7 | 10 mM | [NAME] | Estrogen/progestogen Receptor | Dienogest is an orally active synthetic progesterone (or progestin).
Aniracetam | e7-L1700-13 | 72432-10-1 | 10 mM | S1281 | AMPA Receptor-kainate Receptor-NMDA Receptor | Aniracetam is a nootropics and neuroprotective drug.
Artemisinin | e8-L1700-13 | 63968-64-9 | 10 mM | S1282 |  | Artemisinin is a drug used to treat multi-drug resistant strains of falciparum malaria.
Biperiden HCl | e9-L1700-13 | 1235-82-1, 514-65-8(free base) | 10 mM | S1285 | AChR | Biperiden is an antiparkinsonian agent of the anticholinergic type.
Pamidronate Disodium | e10-L1700-13 | 57248-88-1 | 10 mM | S1311 |  | Pamidronate disodium is a nitrogen containing bisphosphonate, used to prevent osteoporosis.
Edaravone (MCI-186) | e11-L1700-13 | 89-25-8 | 10 mM | S1326 |  | [NAME]), a strong novel free radical scavenger, is used for treatment of patients with acute brain infarction.
Ellagic acid | f1-L1700-13 | 476-66-4 | 10 mM | S1327 | Topoisomerase | Ellagic acid has antiproliferative and antioxidant property.
Felbamate | f2-L1700-13 | 25451-15-4, 1177501-39-1 (H2O) | 10 mM | S1330 |  | Felbamate (Felbatol) is an anticonvulsant drug used in the treatment of epilepsy.
Fluvoxamine maleate | f3-L1700-13 | 61718-82-9, 54739-20-7, 54739-18-3 (free base) | 10 mM | S1336 | 5-HT Receptor | Fluvoxamine maleate is a selective serotonin (5-HT) reuptake inhibitor (SSRI)
Genistein | f4-L1700-13 | 446-72-0 | 10 mM | S1342 | Topoisomerase | Genistein is a soy-derived isoflavone and phytoestrogen with antineoplastic activity.
[NAME] | f5-L1700-13 | 118-00-3 | 10 mM | [NAME]
[NAME] | f6-L1700-13 | 102767-28-2 | 10 mM | S1356 |  | [NAME] is an antiepileptic compound.
Losartan potassium | f7-L1700-13 | 124750-99-8 | 10 mM | S1359 | RAAS | Losartan potassium is an angiotensin II receptor antagonist drug.
[NAME] | f8-L1700-13 | 55079-83-9,925701-88-8 (sodium salt) | 10 mM | S1368 |  | [NAME] is a second generation retinoid used for psoriasis.
Cefoselis sulfate | f9-L1700-13 | 122841-12-7, 122841-10-5 (free base), 911212-25-4 (HCl) | 10 mM | S1371 |  | Cefoselis sulfate is an antibiotic.
Meropenem | f10-L1700-13 | 96036-03-2, 119478-56-7 (3H2O) | 10 mM | S1381 |  | Meropenem is an ultra-broad spectrum injectable antibiotic.
Nafamostat mesylate | f11-L1700-13 | 82956-11-4, 81525-10-2 (free base), 80251-32-7 (HCl) | 10 mM | S1386 | Proteasome | Nafamostat is an anticoagulant.
[NAME] HCl ([NAME]) | g1-L1700-13 | 99614-01-4, 103639-04-9 (HCl, 2H2O) | 10 mM | [NAME] | 5-HT Receptor | [NAME] is a serotonin 5-HT3 receptor antagonist.
Oxcarbazepine | g2-L1700-13 | 28721-07-5 | 10 mM | S1391 | Sodium Channel | Oxcarbazepine is an anticonvulsant and mood stabilizing drug.
Pirarubicin | g3-L1700-13 | 72496-41-4, 95343-20-7 (HCl) | 10 mM | S1393 | Topoisomerase | Pirarubicin is an anthracycline agent.
Pizotifen malate | g4-L1700-13 | 5189-11-7, 15574-96-6 (free base) | 10 mM | S1394 |  | Pizotifen is a benzocycloheptane based agent used for recurrent migraine headaches.
Apocynin (Acetovanillone) | g5-L1700-13 | 498-02-2 | 10 mM | S2425 |  | Apocynin (Acetovanillone) is a selective NADPH-oxidase inhibitor with IC50 of 10 μM.
[NAME] | g6-L1700-13 | 202138-50-9, 201341-05-1 (free base) | 10 mM | S1400 | Reverse Transcriptase | Tenofovir disoproxil fumarate belongs to nucleotide analogue reverse transcriptase inhibitors (nRTIs).
Tigecycline | g7-L1700-13 | 220620-09-7, 197654-04-9 (HCl), 1135871-27-0 (methanesulfonate) | 10 mM | S1403 |  | Tigecycline is a glycylcycline antibiotic.
Vecuronium Bromide | g8-L1700-13 | 50700-72-6, 86029-43-8 (free base), 74531-76-3 (Maleic acid) | 10 mM | S1405 |  | Vecuronium (Norcuron) is a muscle relaxant in the category of non-depolarizing blocking agents.
Cyclocytidine HCl | g9-L1700-13 | 10212-25-6 | 10 mM | S1973
[NAME] (BI-1356) | g10-L1700-13 | 668270-12-0 | 10 mM | S3031 | DPP-4 | [NAME] is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
Rolipram | g11-L1700-13 | 61413-54-5, 85416-74-6 | 10 mM | S1430 | PDE | Rolipram is a PDE4-inhibitor and an anti-inflammatory agent.
Tianeptine sodium | h1-L1700-13 | 30123-17-2, 72797-41-2 (free base) | 10 mM | S1436 | 5-HT Receptor | Tianeptine is a selective serotonin reuptake enhancer (SSRE) compound used for treating major depressive episodes.
Tizanidine HCl | h2-L1700-13 | 64461-82-1, 51322-75-9 (free base) | 10 mM | S1437 | Adrenergic Receptor | Tizanidine is a drug that is used as a muscle relaxant.
Varenicline tartrate | h3-L1700-13 | 375815-87-5, 249296-44-4 (free base), 230615-23-3 (HCl) | 10 mM | [NAME] | AChR | Varenicline is a prescription medication used to treat smoking addiction.
Atazanavir sulfate | h4-L1700-13 | 229975-97-7 | 10 mM | S1457 | HIV Protease | Atazanavir sulfate(BMS-232632-05) is a sulfate salt form of atazanavir (BMS-232632) that is an highly potent HIV protease inhibitor with an EC50 and EC90 of 2.6~5.3 nM and 9~15 nM in cell culture.
Marbofloxacin | h5-L1700-13 | 115550-35-1, 115551-26-3 (HCl) | 10 mM | S1464 |  | Marbofloxacin is a potent antibiotic inhibiting bacterial DNA replication.
Calcitriol (Rocaltrol) | h6-L1700-13 | 32222-06-3 | 10 mM | S1466 |  | Calcitriol is the hormonally active form of vitamin D.
Doxercalciferol (Hectorol) | h7-L1700-13 | 54573-75-0 | 10 mM | S1467 |  | Doxercalciferol (Hectorol) is a synthetic analog of vitamin D.
Alfacalcidol | h8-L1700-13 | 41294-56-8 | 10 mM | S1468 |  | Alfacalcidol is a non-selective VDR activator medication.
Pravastatin sodium | h9-L1700-13 | 81131-70-6, 81093-37-0 (free base) | 10 mM | S3036 | HMG-CoA Reductase | [NAME] sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 μM.
Arecoline | h10-L1700-13 | 300-08-3 | 10 mM | S2614 | AChR | Arecoline is a muscarinic acetylcholine receptor agonist.
Pralatrexate (Folotyn) | h11-L1700-13 | 146464-95-1 | 10 mM | S1497 | DHFR | Pralatrexate(Folotyn) is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines.
Cefaclor (Ceclor) | a1-L1700-14 | 53994-73-3 | 10 mM | S1499 |  | [NAME] is a cephalosporin antibiotic.
Betamethasone (Celestone) | a2-L1700-14 | 378-44-9, 956901-32-9 (XHCl) | 10 mM | S1500 |  | Betamethasone is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.
Sulbactam sodium ([NAME]) | a5-L1700-14 | 69388-84-7 | 10 mM | S2551 |  | Sulbactam sodium ([NAME]) is an irreversible β-lactamase inhibitor.
Estriol | a6-L1700-14 | 50-27-1 | 10 mM | S2466 | Estrogen/progestogen Receptor | Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.
Cyclosporine (Neoral) | a7-L1700-14 | 79217-60-0 | 10 mM | S1514 |  | Cyclosporine (Neoral) is an immunosuppressant drug.
Cidofovir (Vistide) | a8-L1700-14 | 113852-37-2,149394-66-1 (2H20) | 10 mM | S1516 |  | Cidofovir(Vistide) is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis. (IC50= 0.94 μM).
Saxagliptin (BMS-477118,Onglyza) | a9-L1700-14 | 361442-04-8, 709031-78-7 (HCl), 361442-05-9 (TFA) | 10 mM | S1540 | DPP-4 | [NAME] ([NAME], [NAME]) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.
Sulfasalazine (Azulfidine) | a10-L1700-14 | 599-79-1 | 10 mM | S1576 |  | Sulfasalazine (Azulfidine) is a sulfa agent and a derivative of mesalazine used primarily as an anti-inflammatory agent.
Candesartan (Atacand) | a11-L1700-14 | 139481-59-7, 875515-04-1 | 10 mM | S1578 | RAAS | Candesartan (Atacand) is an angiotensin II receptor antagonist with an IC50 of 15 μg/kg
Olmesartan medoxomil (Benicar) | b1-L1700-14 | 144689-63-4, 1112046-13-5 (3HCl) | 10 mM | S1604 | RAAS | Olmesartan medoxomil (Benicar) is a compound which is hydrolyzed to olmesartan that is a selective AT1 subtype angiotensin II receptor antagonist.
Cefoperazone (Cefobid) | b2-L1700-14 | 62893-19-0 | 10 mM | S1611 |  | Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 [NAME]
Silodosin (Rapaflo) | b3-L1700-14 | 160970-54-7 | 10 mM | S1613 | Adrenergic Receptor | [NAME]) is an α1-adrenoceptor antagonist with high uroselectivity.
Sulfapyridine (Dagenan) | b4-L1700-14 | 144-83-2 | 10 mM | [NAME] |  | Sulfapyridine(Dagenan) is a sulfonamide antibacterial.
Naproxen (Aleve) | [NAME] | 26159-34-2, 22204-53-1 (free base) | 10 mM | S1626 | COX | Naproxen (Aleve, Anaprox) is a COX inhibitor for COX-1 and COX-2 with IC50 of 2.2 μg/mL and 1.3 μg/mL, respectively.
Zafirlukast (Accolate) | b6-L1700-14 | 107753-78-6 | 10 mM | S1633 |  | [NAME] is a leukotriene receptor antagonist (LTRA). (IC50=0.6μM, IC50=7.0 µM for CYP2C9)
Amphotericin B (Abelcet) | b7-L1700-14 | 1397-89-3 | 10 mM | S1636 |  | Amphotericin B is a polyene, antifungal antibiotic produced from a strain of Streptomyces nodosus. (IC50=0.028–0.290 μg/ml)
Docosanol (Abreva) | b8-L1700-14 | 661-19-8 | 10 mM | S1637 |  | Docosanol is a saturated fatty alcoholused traditionally as an emollient, emulsifier, and thickener in cosmetics, nutritional supplement. (ED50=2.5 mg/ml for plaque inhibition, and ED50=1.7 mg/ml for inhibition of virus production)
Amprenavir (Agenerase) | b9-L1700-14 | 161814-49-9 | 10 mM | S1639 | HIV Protease | Amprenavir is an human immunodeficiency virus (HIV) protease inhibitor with IC50 of 14.6 ¡À 12.5 ng/ml for wild-type HIV isolate
Methyldopa (Aldomet) | b10-L1700-14 | 555-30-6,884-39-9 (HCl) | 10 mM | S1642 |  | Methyldopa (Aldomet) is a DOPA decarboxylase competitive inhibitor with an ED50 of 21.8 mg/kg.
Dofetilide (Tikosyn) | b11-L1700-14 | 115256-11-6 | 10 mM | S1658 |  | [NAME]) is a class III antiarrhythmic agent.
Isradipine (Dynacirc) | c1-L1700-14 | 75695-93-1 | 10 mM | [NAME] | Calcium Channel | Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 [NAME]
Trichlormethiazide (Achletin) | c2-L1700-14 | 133-67-5, 96782-89-7, 91996-54-2 (sodium salt) | 10 mM | S1667 |  | Trichlormethiazide(Achletin) is a diuretic with properties similar to those of hydrochlorothiazide.
Aminoglutethimide ([NAME]) | c3-L1700-14 | 125-84-8 | 10 mM | S1672 | Aromatase | Aminoglutethimide (AMG, [NAME]) is an aromatase inhibitor with IC50 of 10 μM.
Lubiprostone (Amitiza) | c4-L1700-14 | 136790-76-6 | 10 mM | S1675 |  | Lubiprostone(Amitiza) is a gastrointestinal agent used for the treatment of idiopathic chronic constipation.
Praziquantel (Biltricide) | c5-L1700-14 | 55268-74-1 | 10 mM | S1691 |  | Praziquantel(Biltricide, [NAME]) is an anthelmintic effective against flatworms.
Deferasirox (Exjade) | c6-L1700-14 | 201530-41-8 | 10 mM | S1712 |  | Deferasirox(Exjade) is a rationally-designed oral iron chelator.
Gemcitabine (Gemzar) | c7-L1700-14 | 95058-81-4 | 10 mM | S1714 | DNA/RNA Synthesis | Gemcitabine(Gemzar) belongs to the group of medicines called antimetabolites.
Azathioprine ([NAME], Imuran) | c8-L1700-14 | 446-86-6 | 10 mM | S1721 |  | [NAME], Imuran) is a drug that suppresses the immune system and is used in organ transplantation and autoimmune disease.
Mitotane (Lysodren) | c9-L1700-14 | 53-19-0, 102976-59-0 | 10 mM | S1732 |  | Mitotane(Lysodren), is an antineoplastic medication used in the treatment of adrenocortical carcinoma.
Meloxicam (Mobic) | c10-L1700-14 | 71125-38-7 | 10 mM | S1734 |  | Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects.
Thiabendazole | c11-L1700-14 | 148-79-8 | 10 mM | S1739 |  | Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.
Esomeprazole magnesium (Nexium) | d1-L1700-14 | 161973-10-0 | 10 mM | S1743 | [NAME] | [NAME])  is a proton pump inhibitor to reduce gastric acid secretion.
[NAME] | d2-L1700-14 | 6197-30-4 | 10 mM | S1750 |  | [NAME] is an organic compound used as an ingredient in sunscreens and cosmetics.
Enoxacin (Penetrex) | d3-L1700-14 | 74011-58-8 | 10 mM | S1756 |  | Enoxacin(Penetrex)is an oral broad-spectrum fluoroquinolone antibacterial agent used in the treatment of urinary tract infections and gonorrhea. Insomnia is a common adverse effect.
Suprofen (Profenal) | d4-L1700-14 | 40828-46-4 | 10 mM | S1761 |  | Suprofen(Profenal) is an NSAID.
Rifampin (Rifadin, Rimactane) | d5-L1700-14 | 13292-46-1 | 10 mM | S1764 |  | Rifampin (Rifadin, Rimactane) is a bactericidal antibiotic agent of the rifamycin group.
Beta [NAME] | d6-L1700-14 | 7235-40-7 | 10 mM | S1767 |  | Beta [NAME] is an organic compound and classified as a terpenoid. It is a precursor (inactive form) of vitamin A.
Pramipexole (Mirapex) | d7-L1700-14 | 104632-26-0, 104632-25-9 (2HCl) | 10 mM | [NAME] | Dopamine Receptor | Pramipexole (Mirapex) is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.
Azacitidine (Vidaza) | d8-L1700-14 | 320-67-2 | 10 mM | S1782 | DNA/RNA Synthesis | Azacitidine(Vidaza)and its deoxy derivative, decitabine (5-aza-2′deoxycytidine), are used in the treatment of myelodysplastic syndrome.
Bacitracin zinc | d9-L1700-14 | 1405-89-6 | 10 mM | S1791
Acetylcholine chloride | d10-L1700-14 | 60-31-1 | 10 mM | S1805 | AChR | The chemical compound acetylcholine (ACh) is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.
Nifedipine (Adalat) | d11-L1700-14 | 21829-25-4 | 10 mM | S1808 |  | Nifedipine(Adalat), a potent vasodilator agent with calcium antagonistic action.
Chlorpheniramine Maleate | e1-L1700-14 | 113-92-8,132-22-9 (free base) | 10 mM | [NAME] | Histamine Receptor | Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM.
Gambogic Acid | e2-L1700-14 | 2752-65-0 | 10 mM | S2448
Betaxolol HCl (Betoptic) | e3-L1700-14 | 63659-19-8 | 10 mM | S1827 | Adrenergic Receptor | Betaxolol hydrochloride (Betoptic) is a β1 adrenergic receptor blocker with IC50 of 6 μM.
Proparacaine HCl | e4-L1700-14 | 5875-06-9 | 10 mM | S1828 | Sodium Channel | Proparacaine HCl is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.
Pranlukast | e5-L1700-14 | 103177-37-3 | 10 mM | S1829 |  | Pranlukast is a selective cysteinyl leukotriene receptor antagonist.
Oxfendazole | e6-L1700-14 | 53716-50-0 | 10 mM | S1830 |  | Oxfendazole is the sulfoxide form of fenbendazole which is  a broad spectrum benzimidazole anthelmintic.
Carvedilol | e7-L1700-14 | 72956-09-3 | 10 mM | S1831 | Adrenergic Receptor | Carvedilol is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.
Atracurium besylate | e8-L1700-14 | 64228-81-5 | 10 mM | S1832
Butoconazole nitrate | e9-L1700-14 | 64872-77-1 | 10 mM | S1833
[NAME] (Zithromax) | e10-L1700-14 | 83905-01-5 | 10 mM | S1835
Albendazole Oxide (Ricobendazole) | e11-L1700-14 | 54029-12-8 | 10 mM | S1836
Flubendazole (Flutelmium) | f1-L1700-14 | 31430-15-6 | 10 mM | S1837
Curcumin | f2-L1700-14 | 458-37-7, 15845-47-3, 33171-04-9 | 10 mM | S1848 |  | Curcumin is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae).
Oxibendazole | f3-L1700-14 | 20559-55-1 | 10 mM | S1851
Mifepristone ([NAME]) | f4-L1700-14 | 84371-65-3 | 10 mM | S2606 | Estrogen/progestogen Receptor | Mifepristone ([NAME], RU-486, [NAME], Mifegyne) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively.
Bifonazole | f5-L1700-14 | 60628-96-8 | 10 mM | S1854
Pefloxacin mesylate | f6-L1700-14 | 70458-95-6, 70458-92-3 (free base) | 10 mM | S1855
Metoprolol tartrate | f7-L1700-14 | 392-17-7 | 10 mM | S1856 | Adrenergic Receptor
Etidronate (Didronel) | f8-L1700-14 | 2809-21-4 | 10 mM | S1857
Diethylstilbestrol (Stilbestrol) | f9-L1700-14 | 56-53-1 | 10 mM | S1859 |  | Diethylstilbestrol(Stilbestrol), a synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders.
Diltiazem HCl ([NAME]) | f10-L1700-14 | 33286-22-5 | 10 mM | S1865 |  | Diltiazem HCl ([NAME]) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.
Risedronic acid (Actonel) | f11-L1700-14 | 105462-24-6 | 10 mM | S1874
Tranexamic acid (Transamin) | g1-L1700-14 | 1197-18-8 | 10 mM | S1875
Valaciclovir HCl | g2-L1700-14 | 124832-27-5 | 10 mM | S1876
Ganciclovir | g3-L1700-14 | 82410-32-0 | 10 mM | S1878
Roxatidine acetate HCl | g4-L1700-14 | 93793-83-0 | 10 mM | S1880 | Histamine Receptor
Protionamide (Prothionamide) | g5-L1700-14 | 14222-60-7 | 10 mM | S1881
Idoxuridine | g6-L1700-14 | 54-42-2, 17140-71-5 (H2O) | 10 mM | S1883
Sparfloxacin | g7-L1700-14 | 110871-86-8 | 10 mM | [NAME]
Talc | g8-L1700-14 | 14807-96-6 | 10 mM | S1900 |  | Talc is a mineral composed of hydrated magnesium silicate with the chemical formula H2Mg3(SiO3)4 or Mg3Si4O10(OH)2.
Avobenzone (Parsol 1789) | g9-L1700-14 | 70356-09-1 | 10 mM | S1904 |  | Avobenzone(Parsol 1789) is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative.
Amlodipine (Norvasc) | g10-L1700-14 | 88150-42-9 | 10 mM | S1905 | Calcium Channel | Amlodipine(Norvasc) is a long-acting calcium channel blocker with an IC50 of 1.9 nM.
Metronidazole (Flagyl) | g11-L1700-14 | 443-48-1 | 10 mM | S1907 |  | Metronidazole(Flagyl)is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.
Tioconazole | h1-L1700-14 | 65899-73-2 | 10 mM | S1910
[NAME] | h2-L1700-14 | 15826-37-6 | 10 mM | S1911
Tropicamide | h3-L1700-14 | 1508-75-4 | 10 mM | S1913 | AChR
Pregnenolone | h4-L1700-14 | 145-13-1 | 10 mM | S1914 | Estrogen/progestogen Receptor
Phenindione (Rectadione) | h5-L1700-14 | 83-12-5 | 10 mM | S1921 |  | Phenindione is an anticoagulant which functions as a Vitamin K antagonist.
Alibendol | h6-L1700-14 | 26750-81-2 | 10 mM | S1928
Irsogladine | h7-L1700-14 | 57381-26-7, 84504-69-8 (Maleic acid) | 10 mM | S1929 | AChR | Irsogladine is an anti-gastric ulcer agent that facilitates gap-junctional intercellular communication through M1 muscarininc acetylcholine receptor binding.
Menadione | h8-L1700-14 | 58-27-5 | 10 mM | S1949 |  | [NAME]), a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo.
Sulfamethizole (Proklar) | h9-L1700-14 | 144-82-1 | 10 mM | S1957 |  | Sulfamethizole(Proklar) is a sulfathiazole antibacterial agent.
Sulbactam | h10-L1700-14 | 68373-14-8 | 10 mM | S1958
Tolfenamic acid | h11-L1700-14 | 13710-19-5 | 10 mM | S1959 | COX
Pranoprofen | a1-L1700-15 | 52549-17-4 | 10 mM | S1960
Sulphadimethoxine | a2-L1700-15 | 122-11-2 | 10 mM | S1962
Rimantadine (Flumadine) | a3-L1700-15 | 13392-28-4 | 10 mM | S1964
Meglumine | a4-L1700-15 | 6284-40-8 | 10 mM | S1974
Aripiprazole (Abilify) | a5-L1700-15 | 129722-12-9 | 10 mM | S1975 | 5-HT Receptor
[NAME] HCl | a6-L1700-15 | 91296-87-6 | 10 mM | S1977
Methscopolamine (Pamine) | a7-L1700-15 | 155-41-9 | 10 mM | S1978 | AChR | Methscopolamine (Pamine) is a muscarinic acetylcholine receptor blocker.
Adenine sulfate | a8-L1700-15 | 321-30-2 | 10 mM | S1982 | DNA/RNA Synthesis | Adenine sulfate is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry.
[NAME] HCl | a9-L1700-15 | 153439-40-8, 83799-24-0 (HCl) | 10 mM | S3208 | Histamine Receptor
Meclizine 2HCl | a10-L1700-15 | 1104-22-9 | 10 mM | [NAME]
Mometasone furoate | a11-L1700-15 | 83919-23-7 | 10 mM | S1987 |  | Mometasone furoate is a glucocorticosteroid used topically to reduce inflammation of the skin or in the airways.
Propylthiouracil | b1-L1700-15 | 51-52-5 | 10 mM | S1988 |  | Propylthiouracil is a thyroperoxidase and 5'-deiodinase inhibitor.
Fluticasone propionate (Flonase, Veramyst) | b2-L1700-15 | 80474-14-2 | 10 mM | S1992 |  | Fluticasone propionate (Flonase, Veramyst) is a synthetic corticosteroid which is derived from fluticasone used to treat asthma and allergic rhinitis (hay fever).
Lacidipine (Lacipil, Motens) | b3-L1700-15 | 103890-78-4 | 10 mM | S1994 | Calcium Channel | Lacidipine (Lacipil, Motens) is a L-type calcium channel blocker.
Procarbazine HCl (Matulane) | b4-L1700-15 | 366-70-1 | 10 mM | S1995 | DNA/RNA Synthesis | Procarbazine hydrochloride (Matulane) is a hydrochloride salt form of procarbazine which is a polyfunctional alkylating compound used as an antineoplastic agent.
[NAME] (Zofran) | [NAME] | 99614-02-5 | 10 mM | S1996 | 5-HT Receptor | [NAME] ([NAME]) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
Liranaftate | b6-L1700-15 | 88678-31-3 | 10 mM | S1997
D-Cycloserine | b7-L1700-15 | 68-41-7 | 10 mM | S1998 |  | [NAME] is an analog of the amino acid D-alanine.
Mirtazapine (Remeron, Avanza) | b8-L1700-15 | 85650-52-8 | 10 mM | S2016 |  | Mirtazapine (Remeron, Avanza) is a potent tetracyclic antidepressant.
[NAME] HCl | b9-L1700-15 | 59263-76-2,54340-58-8(free base) | 10 mM | S3204
Formoterol hemifumarate | b10-L1700-15 | 43229-80-7, 67346-48-9 (free base) | 10 mM | S2020 | Adrenergic Receptor | Formoterol hemifumarate is a potent, selective and long-acting β2-adrenoceptor agonist to β2 and β1 receptors with [NAME] of 8.12 and 5.58, respectively.
Chlormezanone (Trancopal) | b11-L1700-15 | 80-77-3 | 10 mM | S2021 |  | Chlormezanone(Trancopal)，a non-benzodiazepine that is used in the management of anxiety. It has been suggested for use in the treatment of muscle spasm.
Ketotifen fumarate (Zaditor) | c1-L1700-15 | 34580-14-8 | 10 mM | S2024 | Histamine Receptor | Ketotifen fumarate ([NAME]) is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.
Urapidil HCl | c2-L1700-15 | 64887-14-5 | 10 mM | S2025 | 5-HT Receptor | Urapidil hydrochloride is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.
Ginkgolide A | c3-L1700-15 | 15291-75-5 | 10 mM | S2026 | GABA Receptor
Ciprofloxacin (Cipro) | c4-L1700-15 | 85721-33-1 | 10 mM | S2027
[NAME] | c5-L1700-15 | 101831-37-2 | 10 mM | S2028
Valproic acid sodium salt (Sodium valproate) | c6-L1700-15 | 1069-66-5, 99-66-1 (FREE BASE) | 10 mM | S1168 | GABA Receptor | Valproic acid sodium salt (Sodium valproate) is a HDAC inhibitor with IC50 of 0.4 mM and also inhibits GABA-transaminase or succinic_x000D_ semialdehyde dehydrogenase.
Flunarizine 2HCl | c7-L1700-15 | 30484-77-6 | 10 mM | S2030 | Calcium Channel
Fenticonazole nitrate | c8-L1700-15 | 73151-29-8 | 10 mM | S2031
Rebamipide | c9-L1700-15 | 90098-04-7 | 10 mM | S2032
Ipriflavone | c10-L1700-15 | 35212-22-7 | 10 mM | S2422 |  | Ipriflavone (7-Isopropoxyisoflavon) is used to inhibit bone resorption.
Epalrestat | c11-L1700-15 | 82159-09-9 | 10 mM | S2035
Aspartame | d1-L1700-15 | 22839-47-0 | 10 mM | S2036
Phentolamine mesilate | d2-L1700-15 | 65-28-1 | 10 mM | S2038 | Adrenergic Receptor
Nimesulide | d3-L1700-15 | 51803-78-2 | 10 mM | S2040 | COX
Dyclonine HCl | d4-L1700-15 | 536-43-6 | 10 mM | S2041
Memantine HCl (Namenda) | d5-L1700-15 | 41100-52-1 | 10 mM | S2043 | AMPA Receptor-kainate Receptor-NMDA Receptor
Cyproheptadine HCl (Periactin) | d6-L1700-15 | 969-33-5 | 10 mM | S2044 | Histamine Receptor
Doxifluridine | d7-L1700-15 | 3094-09-5 | 10 mM | S2045
Pioglitazone HCl (Actos) | d8-L1700-15 | 112529-15-4 | 10 mM | S2046 | P450 (e.g. CYP17)
Lornoxicam (Xefo) | d9-L1700-15 | 70374-39-9 | 10 mM | S2047 | COX
Clindamycin phosphate | d10-L1700-15 | 24729-96-2 | 10 mM | S2048
10-Hydroxycamptothecin | d11-L1700-15 | 19685-09-7 | 10 mM | S2423 | Topoisomerase | 10-Hydroxycamptothecin (10-HCPT, 10-hydroxy-CPT, OHCPT, NSC107124) is a DNA topoisomerase I inhibitor with potent anti-tumor activity.
Strontium ranelate (Protelos) | e1-L1700-15 | 135459-87-9 | 10 mM | S2050 | Calcium Channel
[NAME] (Capoten) | e2-L1700-15 | 62571-86-2, 198342-23-3 (HCl) | 10 mM | S2051 | RAAS
Oxytetracycline dihydrate | e3-L1700-15 | 6153-64-6 | 10 mM | S2052
Cytidine | e4-L1700-15 | 65-46-3 | 10 mM | S2053
Orphenadrine citrate (Norflex) | e5-L1700-15 | 4682-36-4 | 10 mM | S2054 | AChR
[NAME] | e6-L1700-15 | 103766-25-2 | 10 mM | S2055 | Dehydrogenase
FK-506 (Tacrolimus) | e7-L1700-15 | 104987-11-3 | 10 mM | S5003 |  | An immunosuppressive agent and macrolide antibiotic.
Cyclophosphamide monohydrate | e8-L1700-15 | 6055-19-2 | 10 mM | S2057
Tolnaftate | e9-L1700-15 | 2398-96-1 | 10 mM | S2058
Catharanthine | e10-L1700-15 | 2468-21-5, 47416-77-3 | 10 mM | S3202
Bromhexine HCl | e11-L1700-15 | 611-75-6 | 10 mM | S2060
[NAME] (Mevacor) | f1-L1700-15 | 75330-75-5 | 10 mM | S2061 | HMG-CoA Reductase
Tiopronin (Thiola) | f2-L1700-15 | 1953-02-2 | 10 mM | S2062
Suplatast tosylate | f3-L1700-15 | 94055-76-2 | 10 mM | S2015 |  | Suplatast tosylate is a Th2 cytokine inhibitor which is used as an anti-allergic agent.
Balofloxacin | f4-L1700-15 | 127294-70-6 | 10 mM | S2064
Lafutidine | f5-L1700-15 | 118288-08-7 | 10 mM | [NAME] | Histamine Receptor
Moxonidine | f6-L1700-15 | 75438-57-2 | 10 mM | S2066
[NAME] HCl | f7-L1700-15 | 78712-43-3 | 10 mM | S2067
Moclobemide | f8-L1700-15 | 71320-77-9, 64544-22-5 (HCl), 854045-89-9 (Maleic acid) | 10 mM | S3212 | MAO
[NAME] | f9-L1700-15 | 74863-84-6 | 10 mM | S2069
Trifluoperazine 2HCl | f10-L1700-15 | 440-17-5 , 117-89-5(free base),605-75-4 (Maleic acid) | 10 mM | S3201
Mitiglinide calcium | f11-L1700-15 | 145525-41-3 | 10 mM | S2073 | Potassium Channel
[NAME] | g1-L1700-15 | 15574-49-9 | 10 mM | S2074
Rosiglitazone HCl | g2-L1700-15 | 302543-62-0 | 10 mM | S2075 | PPAR
[NAME] (Zestril) | g3-L1700-15 | 83915-83-7 | 10 mM | S2076 | RAAS
[NAME] calcium (Lipitor) | g4-L1700-15 | 134523-03-8 | 10 mM | S2077 | HMG-CoA Reductase
Ubenimex (Bestatin) | g5-L1700-15 | 58970-76-6, 65391-42-6 (HCl), 223763-80-2 (TFA) | 10 mM | S1591 |  | Ubenimex is a competitive aminopeptidase B inhibitor with an IC50 of 100 mg/ml for K562 cells.
Moexipril HCl | g6-L1700-15 | 82586-52-5 | 10 mM | S2079 | RAAS
Cleviprex (Clevidipine) | g7-L1700-15 | 167221-71-8 | 10 mM | S2080 | Calcium Channel
Cilazapril monohydrate ([NAME]) | g8-L1700-15 | 92077-78-6 | 10 mM | S2081 | RAAS
Adiphenine HCl | g9-L1700-15 | 50-42-0 | 10 mM | S2082
Triflusal | g10-L1700-15 | 322-79-2, 74626-40-7 (sodium salt) | 10 mM | S3200 | COX
Duloxetine HCl (Cymbalta) | g11-L1700-15 | 136434-34-9 | 10 mM | S2084 | 5-HT Receptor
Trimebutine | h1-L1700-15 | 39133-31-8 | 10 mM | S2085 | Opioid Receptor
Ivabradine HCl (Procoralan) | h2-L1700-15 | 148849-67-6 | 10 mM | S2086 | Adrenergic Receptor
Rivastigmine tartrate (Exelon) | h3-L1700-15 | 129101-54-8 | 10 mM | S2087 | AChR
Amiodarone HCl | h4-L1700-15 | 19774-82-4 | 10 mM | S1979 | Potassium Channel
Mosapride citrate | h5-L1700-15 | 112885-42-4, 1229354-90-8, 112885-41-3 (free base) | 10 mM | S1385 | 5-HT Receptor | Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
Pimecrolimus | h6-L1700-15 | 137071-32-0, 1000802-56-1 (HCl) | 10 mM | S5004 |  | Inhibitor of inflammatory cytokine secretion
Detomidine HCl | h7-L1700-15 | 90038-01-0, 76631-46-4 (free base) | 10 mM | S2092 | Adrenergic Receptor
Amidopyrine | h8-L1700-15 | 58-15-1 | 10 mM | S3209
Hypoxanthine | h9-L1700-15 | 68-94-0 | 10 mM | S2424 |  | Hypoxanthine is a naturally occurring purine derivative.
[NAME] | h10-L1700-15 | 115-46-8, 595598-07-5, 1798-50-1 (HCl) | 10 mM | [NAME]
[NAME] sodium salt | h11-L1700-15 | 37091-65-9 ,37091-66-0(free base) | 10 mM | S3195 |  | [NAME] is an acylampicillin with a broad spectrum against bacteria.
Articaine HCl | a1-L1700-16 | 23964-57-0 ,23964-58-1(free base) | 10 mM | S3150 |  | Articaine is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue.
Bexarotene | a2-L1700-16 | 153559-49-0 | 10 mM | S2098
Temocapril HCl | a3-L1700-16 | 110221-44-8 | 10 mM | S2099 | RAAS
Gabexate mesylate | a5-L1700-16 | 56974-61-9 | 10 mM | S2101 | Proteasome
Rasagiline mesylate | a6-L1700-16 | 161735-79-1 | 10 mM | S2102 | MAO
Naltrexone HCl | a7-L1700-16 | 16676-29-2 | 10 mM | S2103 | Opioid Receptor
Entacapone | a8-L1700-16 | 130929-57-6,116314-67-1,1047659-02-8(sodium salt) | 10 mM | S3147 |  | Entacapone inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM.
Azasetron HCl (Y-25130) | a9-L1700-16 | 123040-16-4 | 10 mM | S2106 | 5-HT Receptor
Mizolastine (Mizollen) | a10-L1700-16 | 108612-45-9,1056596-82-7 (2HCl) | 10 mM | S2107 | Histamine Receptor
Flunixin meglumin | a11-L1700-16 | 42461-84-7 | 10 mM | S2108 | COX
Altrenogest | b1-L1700-16 | 850-52-2 | 10 mM | S3167 | Estrogen/progestogen Receptor | Altrenogest is a progestogen structurally related to veterinary steroid trenbolone.
Vinpocetine (Cavinton) | b2-L1700-16 | 42971-09-5 | 10 mM | S2110 | Sodium Channel
Lapatinib | b3-L1700-16 | 231277-92-2, 1187538-35-7 (4-methylbenzenesulfonate) | 10 mM | S2111 | EGFR | Lapatinib, used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively.
Blonanserin ([NAME]) | b4-L1700-16 | 132810-10-7 | 10 mM | S2112 | 5-HT Receptor
Cisatracurium besylate (Nimbex) | [NAME] | 96946-42-8 | 10 mM | S2113 | Adrenergic Receptor
Dronedarone HCl (Multaq) | b6-L1700-16 | 141625-93-6 | 10 mM | S2114
[NAME] HCl ([NAME]) | b7-L1700-16 | 168626-94-6 | 10 mM | S2116
Tylosin tartrate | b8-L1700-16 | 74610-55-2,1405-54-5,1401-69-0(free base) | 10 mM | S3162 |  | Tylosin tartrate is a macrolide antibiotic approved for the control of mycoplasmosis in poultry.
Probucol | b9-L1700-16 | 23288-49-5 | 10 mM | S2119
[NAME] HCl | b10-L1700-16 | 131707-23-8 | 10 mM | S2120
Benztropine mesylate | b11-L1700-16 | 132-17-2,86-13-5(free base) | 10 mM | S3163 | Histamine Receptor | Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM.
Flumequine | c1-L1700-16 | 42835-25-6,143984-63-8,42835-68-7(sodium salt) | 10 mM | S3181
Roflumilast (Daxas) | c2-L1700-16 | 162401-32-3 | 10 mM | S2131 | PDE | Roflumilast(Daxas) is a selective, long-acting the enzyme PDE-4 inhibitor with an IC50 of 0.8 nM.
Sitafloxacin hydrate | c3-L1700-16 | 163253-35-8, 163253-37-0 (H2O), 127254-12-0 (free base), 346607-37-2 (HCl) | 10 mM | S2152 |  | Sitafloxacin hydrate is a new-generation, broad-spectrum oral fluoroquinolone antibiotic.
Tebipenem pivoxil (L-084) | c4-L1700-16 | 161715-24-8, 211558-19-9 (HCL) | 10 mM | S2159 |  | Tebipenem pivoxil(L-084) is a novel oral [NAME] antibiotic with an IC50 of 100 μg/ml for human CYP isoforms
Rotundine | c5-L1700-16 | 483-14-7 | 10 mM | S2437 | Calcium Channel | Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM.
[NAME] calcium (Crestor) | c6-L1700-16 | 147098-20-2, 287714-41-4 (free base) | 10 mM | S2169 | RAAS | [NAME] (Crestor) is a member of statins and used to treat high cholesterol and related conditions, and to prevent cardiovascular disease.
Dichlorphenamide (Diclofenamide) | c8-L1700-16 | 120-97-8, 76382-13-3 (disodium salt) | 10 mM | S2177 |  | Diclofenamide (Dichlorphenamide) is a sulfonamide and a carbonic anhydrase inhibitor of the meta-Disulfamoylbenzene class.
Vanillin | c9-L1700-16 | 121-33-5 | 10 mM | S3071 |  | Vanillin is a phenolic aldehyde used as a flavoring agent in foods, beverages, and pharmaceuticals.
Cephalomannine | c10-L1700-16 | 71610-00-9 | 10 mM | S2408 |  | Cephalomannine is an active anti-cancer agent obtained from Taxus yunnanensis and has an antineoplastic effect on tumors found in mice.
10-DAB (10-Deacetylbaccatin) | c11-L1700-16 | 32981-86-5, 115509-92-7 | 10 mM | S2409 |  | 10-DAB (10-Deacetylbaccatin) is an antineoplastic agent and an anti-cancer intermediate.
Paeoniflorin | d1-L1700-16 | 23180-57-6 | 10 mM | S2410 |  | Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.
Geniposide | d2-L1700-16 | 24512-63-8, 27745-20-6 | 10 mM | S2411 |  | Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis.
[NAME] | d3-L1700-16 | 6902-77-8, 1202641-87-9 | 10 mM | S2412 |  | [NAME] is an active aglycone derived from an iridoid glycoside called geniposide, which is found in the fruit of Gardenia jasminoides Ellis.
Geniposidic acid | d4-L1700-16 | 27741-01-1, 103530-48-9 (monosodium salt) | 10 mM | S2413 |  | Geniposidic acid is an effective anticancer and radioprotection agent.
Tolbutamide | d5-L1700-16 | 64-77-7, 100735-34-0, 473-41-6 (sodium salt) | 10 mM | S2443 | Potassium Channel | Tolbutamide is an inhibitor of cAMP with IC50 of 4 [NAME]
[NAME] | d6-L1700-16 | 141505-33-1 | 10 mM | S2446
(+,-)-Octopamine HCl | d7-L1700-16 | 770-05-8, 4502-14-1, 104-14-3 (free base) | 10 mM | S3188
Fluocinolone acetonide (Flucort-N) | d8-L1700-16 | 67-73-2 | 10 mM | S2470 |  | Fluocinolone(Flucort-N) acetonide is a corticosteroid that binds to the cytosolic glucocorticoid receptor.
Nitrendipine | d9-L1700-16 | 39562-70-4 | 10 mM | S2491 | Calcium Channel | Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.
Pantothenic acid (pantothenate) | d10-L1700-16 | 79-83-4 | 10 mM | S2498 |  | Pantothenic acid(pantothenate) is a water-soluble vitamin and an essential nutrient for for many animals.
Phenoxybenzamine HCl | d11-L1700-16 | 63-92-3 | 10 mM | S2499 | Androgen Receptor | [NAME] HCl is a non-specific, irreversible alpha antagonist with an IC50 of 550 nM.
Propafenone (Rytmonorm) | e1-L1700-16 | 54063-53-5 | 10 mM | S2500 | Sodium Channel | Propafenone(Rytmonorm) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.
[NAME] disodium | e2-L1700-16 | 4800-94-6 , 21654-04-6, 26769-14-2, 4697-36-3(free base) | 10 mM | S3179
Roxithromycin (Roxl-150) | e3-L1700-16 | 80214-83-1 | 10 mM | S2506 |  | Roxithromycin(Roxl-150) is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections.
Sulfadoxine (Sulphadoxine) | e4-L1700-16 | 2447-57-6 | 10 mM | S2511 |  | Sulfadoxine(Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax
Tenoxicam (Mobiflex) | e5-L1700-16 | 59804-37-4 | 10 mM | S2512 |  | Tenoxicam(Mobiflex) is a good HO. radicals scavenger with an IC50 of 56.7 μM
Tobramycin | e6-L1700-16 | 32986-56-4 | 10 mM | S2514 |  | Tobramycin is an aminoglycoside antibiotic with an IC50 of 9.7 μM
[NAME] | e7-L1700-16 | 23076-35-9, 7361-61-7 (free base) | 10 mM | S2516 | Adrenergic Receptor | [NAME] HCl is α2 class of adrenergic receptor agonist.
NAD+ | e8-L1700-16 | 53-84-9 | 10 mM | S2518 |  | NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
DL-Adrenaline | e9-L1700-16 | 329-65-7 | 10 mM | S2523 | Adrenergic Receptor | DL-Adrenaline is a hormone and a neurotransmitter secreted by the medulla of the adrenal glands.
Ciclopirox (Penlac) | e10-L1700-16 | 29342-05-0 | 10 mM | S2528 |  | Ciclopirox (Penlac) is a synthetic antifungal agent.
Scopine | e11-L1700-16 | 498-45-3 | 10 mM | S2545 | Adrenergic Receptor
Scopine HCl | f1-L1700-16 | 85700-55-6 | 10 mM | S2548
Amiloride HCl dihydrate | f2-L1700-16 | 17440-83-4 | 10 mM | S2560 | Sodium Channel | Amiloride hydrochloride dihydrate is a potent epithelial sodium channel blocker.
Oxacillin sodium monohydrate | f3-L1700-16 | 7240-38-2 | 10 mM | S2563 |  | Oxacillin sodium monohydrate is an antibacterial agent and is a narrow spectrum beta-lactam antibiotic of the penicillin class.
Medroxyprogesterone acetate | f4-L1700-16 | 71-58-9 | 10 mM | S2567 | Estrogen/progestogen Receptor | Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.
Phenylephrine HCl | f5-L1700-16 | 61-76-7 | 10 mM | S2569 | Androgen Receptor | Phenylephrine hydrochloride is a selective α1-adrenergic receptor agonist.
Streptomycin sulfate | f6-L1700-16 | 3810-74-0 | 10 mM | S2572 |  | Streptomycin sulfate is a sulfate salt of streptomycin that is a protein synthesis inhibitor.
Tetracycline HCl | f7-L1700-16 | 64-75-5 | 10 mM | S2574 |  | Tetracycline hydrochloride is a hydrochloride salt of tetracycline that is a broad-spectrum polyketide antibiotic.
Vancomycin HCl (Vancocin) | f8-L1700-16 | 1404-93-9 | 10 mM | S2575 |  | Vancomycin hydrochloride (Vancocin) is a hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial agent.
Xylometazoline HCl | f9-L1700-16 | 1218-35-5 | 10 mM | S2576
Phenacetin | f10-L1700-16 | 62-44-2 | 10 mM | S2577 | COX | Phenacetin is a non-opioid analgesic without anti-inflammatory properties.
Quinapril HCl (Accupril) | f11-L1700-16 | 82586-55-8 | 10 mM | S2581 | RAAS | Quinapril hydrochloride (Accupril) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.
Thiamphenicol (Thiophenicol) | g1-L1700-16 | 15318-45-3 | 10 mM | S2583 |  | Thiamphenicol (Thiophenicol) is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol.
Clobetasol propionate | g2-L1700-16 | 25122-46-7 | 10 mM | [NAME] |  | Clobetasol propionate is a anti-inflammatory corticosteroid used to treat various skin disorders.
Brompheniramine | g3-L1700-16 | 980-71-2 | 10 mM | S2585 | Histamine Receptor | Brompheniramine is a histamine H1 receptors antagonist.
Dimethyl Fumarate | g4-L1700-16 | 624-49-7 | 10 mM | S2586
Calcium levofolinate (Calcium Folinate) | g5-L1700-16 | 80433-71-2 | 10 mM | S2588 |  | Calcium levofolinate (Calcium Folinate) is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy.
Miglitol (Glyset) | g6-L1700-16 | 72432-03-2 | 10 mM | S2589 |  | Miglitol (Glyset) is an oral anti-diabetic drug.
Pioglitazone (Actos) | g7-L1700-16 | 111025-46-8 | 10 mM | S2590 |  | Pioglitazone (Actos) is a selective peroxisome proliferator-activated receptor gamma stimulator.
Tolvaptan (OPC-41061) | g8-L1700-16 | 150683-30-0 | 10 mM | S2593 | Estrogen/progestogen Receptor | Tolvaptan (OPC-41061) is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28¦ÌM for the inhibition of AVP-induced platelet aggregation.
[NAME] | g9-L1700-16 | 68497-62-1 | 10 mM | S2594 |  | [NAME] is a more potent nootropic drug derived from piracetam.
Clindamycin palmitate HCl | g10-L1700-16 | 25507-04-4 | 10 mM | S2596 |  | Clindamycin palmitate HCl is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.
Oseltamivir phosphate (Tamiflu) | g11-L1700-16 | 204255-11-8 | 10 mM | S2597 |  | Oseltamivir phosphate (Tamiflu) is a competitive neuraminidase inhibitor.
L-Thyroxine | h1-L1700-16 | 51-48-9 | 10 mM | S2599 |  | L-Thyroxine is a synthetic form of thyroxine and a hormone replacement drug.
Amitriptyline HCl | h2-L1700-16 | 549-18-8 ,50-48-6(free base) | 10 mM | S3183 | 5-HT Receptor | Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.
Acemetacin (Emflex) | h3-L1700-16 | 53164-05-9 | 10 mM | S2602 | COX | Acemetacin (Emflex) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
Idebenone | h4-L1700-16 | 58186-27-9 | 10 mM | S2605 |  | Idebenone is a synthetic analog of coenzyme Q10 (CoQ10) and a brain stimulant.
Buflomedil HCl | h5-L1700-16 | 35543-24-9 | 10 mM | S2607
Inulin | h6-L1700-16 | 9005-80-5 | 10 mM | S2609 |  | Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.
Lonidamine | h7-L1700-16 | 50264-69-2 | 10 mM | S2610 |  | [NAME] is an orally administered small molecule hexokinase inactivator with an IC50 of 0.85 [NAME]
Ethisterone | h8-L1700-16 | 434-03-7 | 10 mM | S2611 | Estrogen/progestogen Receptor
Noradrenaline bitartrate monohydrate (Levophed) | h9-L1700-16 | 108341-18-0, 329-56-6 (HCl) | 10 mM | S2615 |  | Noradrenaline bitartrate monohydrate (Levophed) is a direct alpha-adrenergic receptors stimulator.
Peramivir  Trihydrate | h10-L1700-16 | 1041434-82-5 | 10 mM | S2716 |  | Peramivir Trihydrate is a trihydrate of the anti-infection agent peramivir (RWJ-270201,BCX-1812) which is a transition-state analogue and a potent, specific influenza viral neuraminidase inhibitor with an IC50 of median 0.09 nM.
Nilvadipine (ARC029) | h11-L1700-16 | 75530-68-6, 299411-82-8 (H2O) | 10 mM | S2721 | Calcium Channel | Nilvadipine (ARC029) is a potent calcium channel blocker with an IC50 of 0.03 nM.
Astragaloside A | a1-L1700-17 | 83207-58-3 | 10 mM | S2415 | TGF-beta/[NAME] | Astragaloside A is a pure small molecular compound isolated from [NAME] and is commonly used in the treatment of degenerative bone diseases such as osteoporosis.
Abacavir sulfate | a2-L1700-17 | 188062-50-2, 136470-78-5 (FREE  BASE) | 10 mM | S3165 | Reverse Transcriptase | Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.
[NAME] | a3-L1700-17 | 31282-04-9 | 10 mM | S2908
Carbazochrome sodium sulfonate | a4-L1700-17 | 51460-26-5, 70063-04-6 (free base) | 10 mM | S3000
Naftifine HCl | a5-L1700-17 | 65473-14-5 ,65472-88-0(free base) | 10 mM | S3156 |  | Naftifine is an allylamine antifungal drug for the topical treatment of tinea pedis, [NAME], and [NAME], probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme.
Betahistine 2HCl | a6-L1700-17 | 5579-84-0,5638-76-6(free base) | 10 mM | S3176 | Histamine Receptor | Betahistine is a histamine H3 receptors inhibitor with IC50 of 1.9 [NAME]
Azatadine dimaleate | a7-L1700-17 | 3978-86-7, 3964-81-6 (free base) | 10 mM | S3186 | Histamine Receptor | [NAME] is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.
Paroxetine HCl | a8-L1700-17 | 78246-49-8 | 10 mM | S3005 | 5-HT Receptor
Ibandronate sodium | b1-L1700-17 | 138926-19-9,138844-81-2(sodium salt) ,114084-78-5(free base) | 10 mM | S3148 |  | Ibandronate is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
Pazopanib | b2-L1700-17 | 444731-52-6, 790713-33-6, 635702-64-6 (HCl) | 10 mM | S3012 | VEGFR
Plerixafor 8HCl (DB06809) | b3-L1700-17 | 155148-31-5, 110078-46-1 (free base) | 10 mM | S3013 | CXCR | Plerixafor 8HCl (DB06809, Mozobil, AMD3100) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.
Inosine | b4-L1700-17 | 58-63-9 | 10 mM | S2442 |  | Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring via a β-N9-glycosidic bond.
Amoxicillin (Amoxycillin) | [NAME] | 26787-78-0, 34642-77-8 (sodium salt), 61336-70-7 (3H2O) | 10 mM | S3015
Aspirin (Acetylsalicylic acid) | b6-L1700-17 | 50-78-2 | 10 mM | S3017
Niflumic acid | b7-L1700-17 | 4394-00-7, 54821-89-5 (sodium salt) | 10 mM | S3018 | GABA Receptor
Ciclopirox ethanolamine | b8-L1700-17 | 41621-49-2 | 10 mM | [NAME] | ATPase | Ciclopirox ethanolamine (Ciclopirox olamine, HOE 296) is a broad-spectrum antifungal agent working as an iron chelator.
[NAME] (FK228 ,depsipeptide) | b9-L1700-17 | 128517-07-7 | 10 mM | S3020 | HDAC | [NAME] (FK228, FR901228, depsipeptide, NSC 630176) is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.
Rimonabant (SR141716) | b10-L1700-17 | 168273-06-1, 948565-21-7, 158681-13-1 (HCl) | 10 mM | S3021 | Cannabinoid Receptor | Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane.
Cabazitaxel (Jevtana) | b11-L1700-17 | 183133-96-2, 890654-44-1 | 10 mM | S3022 |  | Cabazitaxel (Jevtana, [NAME]) is a semi-synthetic derivative of a natural taxoid.
Bufexamac | c1-L1700-17 | 2438-72-4, 1353882-38-8 (sodium salt) | 10 mM | S3023 | COX | Bufexamac is a COX inhibitor for IFN-α release with EC50 of 8.9 μM.
[NAME] | c2-L1700-17 | 84057-84-1, 375347-20-9 (H2O), 493025-05-1 (HCl) | 10 mM | S3024 | Sodium Channel | [NAME] is a novel anticonvulsant drug for inhibition of 5-HT with IC50 of 240 μM and 474 μM in human platelets and rat brain synaptosomes, respectively.
PMSF ([NAME]) | c3-L1700-17 | 329-98-6 | 10 mM | S3025 |  | PMSF (Phenylmethyl sulfonyl fluoride) is an irreversible serine/cysteine protease inhibitor.
Fenoprofen calcium hydrate | c4-L1700-17 | 71720-56-4, 53746-45-5, 154506-73-7, 29679-58-1 (FREE BASE) | 10 mM | S3027 |  | Fenoprofen calcium hydrate (Nalfon) is a non-steroidal anti-inflammatory drug (NSAID).
Niclosamide (Niclocide) | c5-L1700-17 | 50-65-7, 40321-86-6 (sodium salt), 73360-56-2 (H2O) | 10 mM | S3030 | STAT | Niclosamide can inhibit DNA replication and inhibit STAT with IC50 of 0.7 μM.
Bindarit | c6-L1700-17 | 130641-38-2, 1027630-15-4 (sodium salt) | 10 mM | S3032 |  | Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.
Vildagliptin (LAF-237) | c7-L1700-17 | 274901-16-5, 565453-38-5, 924914-75-0 (HCl) | 10 mM | S3033 | DPP-4 | Vildagliptin (LAF-237) inhibits DPP−4 with IC50 of 2.3 nM.
Daunorubicin HCl (Daunomycin HCl) | c8-L1700-17 | 23541-50-6, 20830-81-3 (free base) | 10 mM | S3035 | Telomerase | Daunorubicin HCl inhibits both DNA and [NAME] synthesis and inhibits DNA synthesis with [NAME] of 0.02 μM.
[NAME] | c9-L1700-17 | 190786-44-8, 125602-71-3 (free base), 210095-37-7 (H2O4S) | 10 mM | S3037 | Histamine Receptor
Fosaprepitant dimeglumine | c10-L1700-17 | 265121-04-8, 172673-20-0(free base) | 10 mM | S3038 |  | Fosaprepitant (MK-0517, L-758,298) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.
Droxidopa (L-DOPS) | c11-L1700-17 | 23651-95-8, 1260173-94-1 (HCl) | 10 mM | S3041 |  | Droxidopa (L-DOPS) is a psychoactive drug and acts as a prodrug to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline).
Rofecoxib (Vioxx) | d1-L1700-17 | 162011-90-7 | 10 mM | S3043 | COX | Rofecoxib ([NAME]) is a COX-2 inhibitor with IC50 of 18 nM.
Lurasidone HCl | d2-L1700-17 | 367514-88-3 | 10 mM | S3044 | Dopamine Receptor
Cinepazide maleate | d3-L1700-17 | 26328-04-1, 23887-46-9 (free base) | 10 mM | S3045 |  | Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator.
Azilsartan (TAK-536) | d4-L1700-17 | 147403-03-0, 147388-92-9 (disodium salt) | 10 mM | S3046 | RAAS | Azilsartan (TAK-536) is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM.
[NAME] | d5-L1700-17 | 26095-59-0 , 105360-89-2 (free base) | 10 mM | S3047 | AChR | Otilonium bromide is an antimuscarinic.
Solifenacin succinate | d6-L1700-17 | 242478-38-2, 242478-37-1 (free base), 180468-39-7 (HCl) | 10 mM | S3048 | AChR | Solifenacin succinate is a urinary antispasmodic of the antimuscarinic class.
Palonosetron HCl | d7-L1700-17 | 135729-62-3, 135729-61-2 (free base), 873312-28-8 (H2O4S) | 10 mM | S3050 | 5-HT Receptor | Palonosetron HCl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
Azelnidipine | d8-L1700-17 | 123524-52-7, 116574-11-9 (2HCl) | 10 mM | S3053 | Calcium Channel | Azelnidipine is a dihydropyridine calcium channel blocker.
[NAME] | d9-L1700-17 | 5560-59-8 | 10 mM | S3054 |  | Alverine citrate is a drug used for functional gastrointestinal disorders.
Besifloxacin HCl (Besivance) | d10-L1700-17 | 405165-61-9, 141388-76-3 (free base) | 10 mM | S3055 |  | Besifloxacin HCl is a fourth-generation fluoroquinolone antibiotic.
[NAME] (TAK-491) | d11-L1700-17 | 863031-21-4 | 10 mM | S3057 | RAAS
Danofloxacin Mesylate | e1-L1700-17 | 119478-55-6 | 10 mM | S3058
Enrofloxacin | e2-L1700-17 | 93106-60-6, 93106-59-3 (HCl), 266346-15-0 (sodium salt ) | 10 mM | S3059 |  | Enrofloxacin is a fluoroquinolone antibiotic.
Medetomidine HCl | e3-L1700-17 | 86347-15-1, 86347-14-0 (free base) | 10 mM | S3060 | Adrenergic Receptor
Ampicillin sodium | e4-L1700-17 | 69-52-3, 24863-47-6, 57748-55-7, 69-53-4 (free base) | 10 mM | S3170 |  | Ampicillin is a beta-lactam antibiotic that is part of the [NAME] family.
Diclofenac Potassium | e5-L1700-17 | 15307-81-0, 15307-86-5 (free base) | 10 mM | S3062 |  | Diclofenac potassium is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
Diclofenac Diethylamine | e6-L1700-17 | 78213-16-8, 15307-86-5 (free base) | 10 mM | S3063 |  | Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.
Amikacin sulfate | e7-L1700-17 | 39831-55-5, 37517-28-5 (free base) | 10 mM | S3065 |  | Amikacin sulfate binds to 16S rRNA (bacterial 30S ribosome), causing misreading of mRNA and supressing proteins synthesis.
Naloxone HCl | e8-L1700-17 | 357-08-4, 465-65-6 (free base) | 10 mM | S3066 | Opioid Receptor
(R)-baclofen | e10-L1700-17 | 69308-37-8, 63701-55-3 (HCl) | 10 mM | S3072 | GABA Receptor | (R)-baclofen is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.
[NAME] valerate | f1-L1700-17 | 979-32-8,907-12-0, 69557-95-5 | 10 mM | S3149 | Estrogen/progestogen Receptor | [NAME] is a synthetic ester used to treat menopausal symptoms and hormone deficiencies.
Gliquidone | f2-L1700-17 | 33342-05-1,62783-47-5(sodium salt) | 10 mM | S3151 | Potassium Channel | Gliquidone is an ATP-sensitive K+ channel antagonist with IC50 of 27.2 nM.
Butenafine HCl | f3-L1700-17 | 101827-46-7 ,101828-21-1(free base) | 10 mM | S3154 |  | Butenafine HCl is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
Mepivacaine HCl | f4-L1700-17 | 1722-62-9 ,16452-56-5, 38423-99-3,96-88-8(free base) | 10 mM | S3155 |  | Mepivacaine is a tertiary amine used as a local anesthetic.
Atovaquone (Atavaquone) | f5-L1700-17 | 95233-18-4 | 10 mM | S3079 |  | Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
Etravirine (TMC125) | f6-L1700-17 | 269055-15-4, 1030633-39-6 (HCl), 1030633-41-0 (4-methylbenzenesulfonate) | 10 mM | [NAME] | Reverse Transcriptase | Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
Ulipristal | f7-L1700-17 | 126784-99-4 | 10 mM | S3081 |  | Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.
Indacaterol Maleate | f8-L1700-17 | 753498-25-8 | 10 mM | S3083 | Adrenergic Receptor
Tirofiban | f9-L1700-17 | 144494-65-5 | 10 mM | S3085 |  | Tirofiban (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.
2-Thiouracil | f10-L1700-17 | 141-90-2 | 10 mM | S3100 |  | 2-Thiouracil is a thiolated uracil derivative that is a known antihyperthyroid agent._x000D_
Creatinine | f11-L1700-17 | 60-27-5 | 10 mM | S3102 |  | Creatinine is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body._x000D_
Moguisteine | g1-L1700-17 | 119637-67-1,161364-62-1 | 10 mM | S3104 |  | Moguisteine is a novel peripheral non-narcotic antitussive drug._x000D_
Nadifloxacin | g2-L1700-17 | 124858-35-1,81962-84-7 | 10 mM | S3105 |  | Nadifloxacin is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris._x000D_
Anagrelide HCl | g3-L1700-17 | 58579-51-4, 68475-42-3 (free base) | 10 mM | S3172 | PDE | Anagrelide is a drug used for the treatment of essential thrombocytosis.
Antipyrine | g4-L1700-17 | 60-80-0, 5779-41-9, 123175-91-7 | 10 mM | S3173 |  | Antipyrine is an analgesic and antipyretic agent.
[NAME] (Ascorbic acid) | g5-L1700-17 | 50-81-7, 14536-17-5, 30208-61-8 | 10 mM | S3114
Sulfathiazole | g6-L1700-17 | 72-14-0, 6052-33-1, 158269-46-6, 144-74-1 (sodium salt) | 10 mM | S3116
Oxybutynin chloride | g7-L1700-17 | 1508-65-2,99937-06-1,5633-20-5(free base) | 10 mM | S3117 | AChR | Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
Ornidazole | g9-L1700-17 | 16773-42-5, 95880-34-5, 166734-79-8 | 10 mM | S3121 |  | Ornidazole is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria._x000D_
Amikacin hydrate | g10-L1700-17 | 1257517-67-1, 37517-28-5 (free base) | 10 mM | S3122 |  | Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections._x000D_
Dexamethasone acetate | g11-L1700-17 | 1177-87-3, 55812-90-3 (H2O) | 10 mM | S3124 |  | Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs used as an anti-inflammatory and immunosuppressant._x000D_
Trimethoprim | h1-L1700-17 | 738-70-5, 56585-33-2 (1/2H2O4S) | 10 mM | S3129 |  | Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections._x000D_
[NAME] ([NAME]) | h2-L1700-17 | 58-85-5, 3672-05-7, 15720-24-8, 56085-82-6 (sodium salt) | 10 mM | S3130 |  | Biotin is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids._x000D_
Sulfamerazine | h3-L1700-17 | 127-79-7, 99482-27-6, 127-58-2 (sodium salt) | 10 mM | S3132
Sulfamethazine | h4-L1700-17 | 57-68-1 | 10 mM | S3133 |  | Sulfamethazine is a sulfonamide antibacterial._x000D_
L-Arginine HCl | h5-L1700-17 | 1119-34-2 ,74-79-3(free base) | 10 mM | S3174 |  | L-Arginine is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
Sodium salicylate | h6-L1700-17 | 54-21-7, 69-72-7 (free base) | 10 mM | S3137 |  | Sodium salicylate is used in medicine as an analgesic and antipyretic._x000D_
Methylthiouracil | h7-L1700-17 | 56-04-2, 1123-10-0, 31909-18-9 | 10 mM | S3138 |  | Methylthiouracil is an antithyroid preparation._x000D_
Methenamine (Mandelamine) | h8-L1700-17 | 100-97-0 | 10 mM | S3139 |  | Methenamine is an antibiotic used for the treatment of urinary tract infection.
Milnacipran HCl | h9-L1700-17 | 101152-94-7, 86181-08-0 ,92623-85-3(free base) | 10 mM | S3140 |  | Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.
[NAME] HBr | h10-L1700-17 | 133099-07-7,133099-04-4(free base) | 10 mM | [NAME] | AChR | [NAME] is a selective M3 muscarinic receptor antagonist with pKi of 8.9.
Tripelennamine HCl | h11-L1700-17 | 154-69-8 ,91-81-6(free base) | 10 mM | S3146 | Histamine Receptor | Tripelennamine is a widely used H1 antagonist, inhibiting PhIP glucuronidation with IC50 of 30 [NAME]