Camelid TB Serology Quarterly Report 1 April - 30 June 2019
Source: environment.data.gov.uk (2024-10-03)

Camelid TB Serology Quarterly Report. Camelid TB Serology Quarterly Report.

Camelid TB Serology
Quarterly Report
Number: 17
Report Period 1st April to 30th June 2019
Issued 23 August 2019

Submission Reason
Explanation
APHA /DEFRA
At Government expense
Parallel Test:
PAR-TB
TB breakdown herd with confirmed M. bovis infection (including Wales where Officially
TB Free Withdrawn [OTFW] status is determined on epidemiological grounds)
PAR-SUS
TB strongly suspected but not currently confirmed by laboratory culture – herd under
restrictions
PAR-TRC
Forward  tracing(s) from an M. bovis-infected camelid herd (includes camelid herds in
Wales only co-located on the same premises with infected cattle, sheep, deer, goats
& pigs)
Serial Test:
SER-CONT
Herd not under restriction but contiguous to a TB-infected herd
SER-COL
Herd not under restriction but co-located with an infected herd of cattle, deer, goats
etc. (Eng & Scot only)
SER-EPI
Herd not under restriction but TB tested due to an epidemiological link with a known
infected herd (e.g. back-tracing)
Commercial/Private
At Owner expense
SER-MVT
Pre- or post-movement test
SER-EXP 
Pre-export test
SER-DIAG
Diagnostic to exclude TB from a differential diagnoses in a herd not restricted (TB
strongly suspected)
SER-RHT
Monitoring - voluntary routine testing (herd nor restricted)
Quarterly Camelid Serology Report
Test Criteria
The camelid TB serology (antibody) test generally comprises two separate antibody tests in a test package that can be
applied flexibly to increase the sensitivity or specificity of the test as required, by using a parallel or serial test
interpretation respectively. The sensitivity and specificity values of combined antibody testing for camelids were described
under AHVLA Project FT1477 (see Rhodes et al., 2012) and re-assessed in May 2018 to show the following test
performance;
Table 1 – High Sensitivity / Parallel test options:
IDEXX /DPP VetTB
ENFER 2-SPOT/DPP VetTB
IDEXX/ENFER 2-SPOT
% Se
74
71
75
95% C.I.
65.4-82.6
62.1-79.9
66.5-83.5
% Sp
96
96.7
97.3
95% C.I.
93.8-98.2
95.8-99.4
95.4-99.1
Fishers Exact [2-sided] test showed no significant difference in sensitivity or specificity between any of these three test options.
Table 2 – High Specificity / Serial test options:
Fishers Exact [2-sided] test showed no significant difference in test sensitivity or specificity between these two test options.
ENFER 4-SPOT
IDEXX/DPP VetTB
% Se
60
56
95% C.I.
50.4-69.9
46.3-65.7
% Sp
99.66
100
95% C.I.
98.9-100
Rhodes, S., Holder, T., Clifford, D., Dexter, I., Brewer, J., Smith, N., Waring, L., Crawshaw, T., Gillgan, S., Lyashchenko,
K., Lawrence, J., Clarke, J., de la Rua-Domenech, R., Vordermeier, M., 2012. Evaluation of gamma interferon and
antibody tuberculosis tests in alpacas. Clin Vaccine Immunol 19, 1677-1683.

Quarterly Camelid Serology Report
23 Aug 2019
Table 1a
Country
No.
Samples
Tested
England
671
Wales
79
Non GB
2
Total for Q2
752
Number of Samples tested and Submission Reason  2019 Q2 (April - June)
Table 1b
Submission
Reason
No.
Samples
Tested
Parallel
PAR-SUS
409
PAR-TB
42
PAR-TRC
16
Parallel
Sum:
467
Serial
SER-COL
38
SER-CONT
221
Serial
Sum:
259
Commercial/Private Testing SER-MVT
23
SER-RHT
3
Commercial/Private Testin
Sum:
26
Total for Q2
Sum:
752

Quarterly Camelid Serology Report
###########
Table 2a
Country
No.
Samples
Tested
England
1203
Wales
103
Non GB
2
Total for Q2
1308
Number of Samples tested and Submission Reason 2019 up to end of Q2 (January - June)
Table 2b
APHA/DEFRA
Submission
Reason
No.
Samples
Tested
Parallel
PAR-SUS
564
PAR-TB
62
PAR-TRC
16
Parallel
Sum:
642
Serial
SER-COL
70
SER-CONT
558
SER-EPI
1
Serial
Sum:
629
Commercial/Private Testing
SER-EXP
7
SER-MVT
26
SER-RHT
4
Commercial/Private Testing
Sum:
37
Total for 2019 up to end
of Q2
1308

Quarterly Camelid Serology Report
23 Aug 2019
Table 3a
Submissions Received and Test Positivity in 2019 Q2
Country
Submission
Reason
No.
Submissions
No. Samples
Tested
No.
Positive
Samples
% Positive
Samples
England
Parallel
PAR-SUS
2
409
15
3.7%
PAR-TRC
4
14
0
0
Parallel
6
423
15
3.5%
Serial
SER-COL
4
38
1
2.6%
SER-CONT
29
186
8
4.3%
Serial
33
224
9
4.0%
Commercial/Private Testing
SER-MVT
5
21
0
0
SER-RHT
1
3
0
0
Commercial/Private Testing
6
24
0
0
England Total
45
671
24
3.6%
Wales
Parallel
PAR-TB
1
42
0
0
PAR-TRC
1
2
0
0
Parallel
2
44
0
0
Serial
SER-CONT
6
35
0
0
Serial
6
35
0
0
Wales Total
8
79
0
0
Non GB
Commercial/Private Testing
SER-MVT
1
2
0
0
Commercial/Private Testing
1
2
0
0
Non GB Total
1
2
0
0
Totals for Q2
54
752
24
3.2 %
Test Positivity in 2019 Q2 (April - June)

Quarterly Camelid Serology Report
23 Aug 2019
Table 3b
Submissions Received and Test Positivity in 2019 up to the end of Q2
Country
Submission
Reason
No.
Submissions
No. Samples
Tested
No.
Positive
Samples
% Positive
Samples
England
Parallel
PAR-SUS
3
564
16
2.8%
PAR-TB
1
20
0
0
PAR-TRC
4
14
0
0
Parallel
8
598
16
2.7%
Serial
SER-COL
7
66
1
1.5%
SER-CONT
62
504
11
2.2%
Serial
69
570
12
2.1%
Commercial/Private Testing
SER-EXP
1
7
0
0
SER-MVT
6
24
0
0
SER-RHT
2
4
0
0
Commercial/Private Testing
9
35
0
0
England Total
86
1,203
28
2.3%
Wales
Parallel
PAR-TB
1
42
0
0
PAR-TRC
1
2
0
0
Parallel
2
44
0
0
Serial
SER-COL
2
4
0
0
SER-CONT
12
54
0
0
SER-EPI
1
1
0
0
Serial
15
59
0
0
Wales Total
17
103
0
0
Non GB
Commercial/Private Testing
SER-MVT
1
2
0
0
Commercial/Private Testing
1
2
0
0
Non GB Total
1
2
0
0
Totals up to
end Q2
104
1,308
28
2.1 %
Test Positivity in 2019 up to end of Q2 (January - June)

Quarterly Camelid Serology Report
23 Aug 2019
Submissions Received in 2019 up to end of Q2
Analysis
Analysis Description
Q1
No.
samples
tested
Q2
No.
samples
tested
Totals up to end Q2
TC0503
Camelid TB Enferplex - 2
Spot
175
422
597
TC0603
Camelid TB Enferplex - 4
Spot
244
193
437
TC0615
Camelid TB DPP VetTB
antibody test
312
559
871
TC0867
Camelid TB Antibody
ELISA
137
137
274
Table 4: Number of samples Tested by Test Code