Call for data: safety of cosmetic ingredients
Source: gov.uk (2025-10-09)

OPSS would like to invite any interested parties to submit any scientific information relevant to the safety assessment of cosmetic ingredients.

The Office for Product Safety and Standards (OPSS) would like to invite any interested parties, including academia, manufacturers of cosmetic products, producers of the substances concerned and consumer associations to submit any scientific information relevant to the safety assessment of cosmetic ingredients in the list below.

OPSS would like to evaluate the safety of these ingredients in cosmetic products due to their suspected endocrine disrupting properties. If ingredients will be used in products that may foreseeably be used by children or pregnant women, relevant additional data to support the safety and exposure estimates should be provided for these specific populations.

Any scientific data submitted for the safety assessment must include all relevant elements as prescribed in the Scientific Committee on Consumer Safety Notes of Guidance for the Testing of Cosmetic Ingredients and Their Safety Evaluation.

Note: The Scientific Advisory Group on Chemical Safety (SAG-CS) will use 70 kg as their default bodyweight assumption for adults in new safety assessments. This aligns with other UK groups, such as the UK Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment, who carry out chemical risk assessments across a range of sectors and have agreed that a default adult bodyweight of 70 kg is representative for the UK adult population. For more information, see SAG-CS (https://www.gov.uk/government/groups/scientific-advisory-group-on-chemical-safety-in-consumer-products).

Please submit original study reports and literature in full for all data relied upon in the safety assessment. This is particularly important for the pivotal studies, those which support the critical ‘No Observed Adverse Effect Level’ (NOAEL) and point of departure and the dermal absorption value. OPSS takes the examination of data very seriously and will ensure independent scientific review of all information sent to us.

How to submit data

Please submit relevant data by email to xxx@xxx.xx (mailto:xxx@xxx.xx)

Note: The data submitted may be subject to the Freedom of Information Act 2000. Any confidential and commercially sensitive data should ONLY be submitted if it is relevant to the safety assessment. Any confidential and commercially sensitive data must be very clearly marked in a submission. Any data that is not marked as confidential and /or commercially sensitive may be liable for release under an appropriate request.

List of chemicals
- Benzophenone-1 (CAS 131-56-6)
- Benzophenone-2 (CAS 131-55-5)
- Benzophenone -4 (CAS 4065-45-6)
- Benzophenone-5 (CAS 6628-37-1)
- Ethylhexyl methoxycinnamate (CAS 5466-77-3/83834-59-7)
- Triphenyl phosphate (CAS 115-86-6)
- Butylated hydroxyanisole (CAS 25013-16-5)
Deadline for submission: 31 March 2026

For further information, please email to xxx@xxx.xx (mailto:xxx@xxx.xx)

Data protection

OPSS is committed to processing information in accordance with the UK General Data Protection Regulation (UK GDPR) and the Data Protection Act 2018 (DPA 2018). The personal data collected on this form will be held securely and will only be used for administrative purposes. If you would like to understand what personal information OPSS collects about you, how OPSS uses this personal information, and what rights you have regarding your personal information, then please refer to our Privacy Notice (https://www.gov.uk/government/publications/safety-and-standards-privacy-notice).