lordswrans/lordswrans2025-06-30 conversation_6
Source: hansard.parliament.uk (2025-06-30)

UK Parliament Hansard data: lordswrans/lordswrans2025-06-30 conversation_6

Lord Kamall:To ask His Majesty's Government what are the Health Data Research UK projects that access NHS data where specific project independent review was not received from NHS England's Advisory Group for Data, and what is the current status of those projects. \p Baroness Merron: NHS England has a Data Sharing Agreement, project identification code DARS-NIC-381078-Y9C5K, with a consortium of academic organisations in the United Kingdom for the purpose of the Health Data Research UK-led, British Heart Foundation Data Science Centre’s CVD-COVID-UK programme.

This agreement was put in place by NHS Digital prior to its merger with NHS England in 2023, and prior to the establishment of NHS England’s Advisory Group for Data (AGD). The AGD was informed of a Senior Information Risk Owner decision to approve an amendment to the agreement on 22 February 2024.

The agreement was subject to reviews by NHS Digital’s Independent Group Advising on the Release of Data (IGARD) on 25 June 2020, 23 July 2020, 15 October 2020, 3 December 2020, 25 February 2021, 29 July 2021, 29 July 2021, 5 May 2022, and 24 November 2022. It was also subject to advice from the Professional Advisory Group on 24 June 2020 and 28 July 2021.

The agreement allowed the data controllers under that agreement to approve access to National Health Service data for individual projects, subject to approval per project by the CVD-COVID-UK oversight committee, which included a representative of NHS Digital/NHS England. Individual projects were not reviewed by IGARD or the AGD.

Under the terms of the agreement, the CVD-COVID-UK oversight committee is required to maintain a list of projects undertaken under the agreement and provide a quarterly report to NHS Digital/NHS England. The following table lists the projects and their current status from the latest report provided in April 2025:

Secure Data Environment research project reference

Current project status

Project title

CCU001

Live - Data in Use

Investigating the effects of angiotensin converting enzyme inhibitors and angiotensin receptor blockers on COVID-19 outcomes

CCU002

Live - Data in Use

SARS-CoV-2 infection and vaccination and the risk of vascular events

CCU003

Live - Data in Use

Direct and indirect effects of the COVID-19 pandemic in individuals with cardiovascular disease (CVD)

CCU004

Live - Data in Use

COVID-19 and CVD risk prediction

CCU005

Live - Data in Use

Data management and analysis methods

CCU007

Live - Data in Use

Impact of COVID-19 pandemic on heart disease patients undergoing cardiac surgery

CCU008

Completed

Evaluating impact of COVID-19 pandemic on the prevalence and management of risk factors

CCU010

Live - Data in Use

In people with CVD and COVID-19, what is the influence of multi-morbidity on risk of poorer outcomes?

CCU013

Live - Data in Use

High-throughput electronic health record phenotyping approaches

CCU014

Live - Data in Use

Assessing the impact of COVID-19 on clinical pathways using a medicines approach

CCU018

Live - Data in Use

COVID-19 infection during pregnancy on CVD and related risk factors

CCU019

Live - Data in Use

Identification and personalised risk prediction for severe COVID-19 in patients with rare disorders impacting cardiovascular health

CCU020

Completed

Evaluation of antithrombotic use and COVID-19 outcomes

CCU022

Live - Data in Use

Genomics of multimorbidity and CVD associated with susceptibility to COVID-19 infection and complications

CCU023

Live - Data in Use

Repurposing medicines used to treat CVD risk to prevent COVID-19

CCU024

Completed

CovPall-Connect. Evaluation of how palliative and end of life care teams have responded to COVID-19: Connecting to boost impact and data assets

CCU028

Live - Data in Use

Coronary revascularisation and outcomes before and after the COVID-19 pandemic

CCU029

Live - Data in Use

Child hospital admission with COVID-19: risk factors; risk groups; and NHS care utilisation

CCU030

Live - Data in Use

Examining potential factors underlying the increased risk of severe COVID-19 experienced by people with intellectual and developmental disabilities

CCU032

Live - Data in Use

The effects of COVID-19 on heart failure subtypes

CCU035

Completed

Are people with COVID-19 and pre-existing respiratory disease at a higher risk of future cardiovascular and venous thromboembolic events compared with COVID-19 patients without pre-existing respiratory disease?

CCU036

Live - Data in Use

The impact of previous exposure to COVID-19 and the safety of COVID-19 vaccination for fertility and pregnancy outcomes

CCU037

Live - Data in Use

Improving methods to minimise bias in ethnicity data for more representative and generalisable models, using CVD in COVID-19 as an example

CCU038

Live - Data in Use

Evaluating the impact of COVID-19 on critical care outcomes

CCU040

Completed

Investigating why some people with diabetes have a greater risk of becoming seriously unwell or dying with COVID-19

CCU043

Live - Data in Use

Investigating new onset diabetes following COVID-19 infection

CCU045

Live - Data in Use

The impact of COVID-19 on heart failure epidemiology, quality of care and outcomes across primary and secondary care

CCU046

Live - Data in Use

Severe mental illness and receipt of acute cardiac care and mortality following myocardial infarction

CCU049

Live - Data in Use

Healthcare utilisation in individuals with Long COVID

CCU051

Completed

Un-vaccination and under-vaccination against SARS-CoV-2 in the UK

CCU052

Live - Data in Use

An observational retrospective cohort study describing the changing epidemiology pre, during and post COVID-19 of asthma, interstitial lung disease, and chronic obstructive pulmonary disease in England

CCU053

Live - Data in Use

Risks and benefits of treatment with SGLT2 inhibitors and the impact of intercurrent illness with COVID-19

CCU056

Completed

Socio-demographic make-up of patients undergoing surgical and transcatheter aortic valve intervention in England and the impact of COVID-19 on this

CCU057

Live - Data in Use

Risks for mortality in people with severe mental illnesses during the COVID-19 pandemic

CCU058

Live - Data in Use

COVID-19 impact on the long-term outcomes of Improving Access to Psychological Therapies in people with long-term cardiovascular conditions

CCU059

Completed

Which combinations of multiple long-term conditions are associated with the greatest risk of hospital admission over the winter season, and to what extent does COVID-19 or influenza vaccination modify this risk?

CCU060

Live - Data in Use

Improving characterisation, prediction and intervention for COVID-19 and influenza-related morbidity and mortality

CCU063

Live - Data in Use

The effect of COVID-19 on maternal and paediatric health among individuals whose first language isn’t English and require an interpreter in England: from preconception to adolescence

CCU064

Live - Data in Use

Impact of COVID-19 clinical care pathway changes on gestational diabetes incidence and pregnancy outcomes in England

CCU066

Live - Data in Use

Changes in acute cardiac care of patients with reduced kidney function during the COVID-19 pandemic

CCU068

Completed

The impact of vaccination on the excess clinical risks of COVID-19 in patients with congenital heart disease

CCU069

Live - Data in Use

RARE-CVD-COVID: To understand COVID-19 impact on intersectional disparity in rare versus common cardiometabolic diseases: CVD and metabolic diseases, including diabetes

CCU070

Live - Data in Use

Supporting novel trial designs using healthcare systems data to mitigate the impact of COVID-19 on diabetes research

CCU071

Live - Data in Use

A regional approach for policy makers to tackle health inequalities in CVD and its risk factors

CCU072

Live - Data in Use

Influence of COVID-19 on British burden of CVD

CCU073

Live - Data in Use

Impact of COVID-19 on the association between Type 2 diabetes and incidence of CVD

CCU074

Live - Data in Use

Improving the accuracy, equity and efficiency of using healthcare systems data for recruitment to a clinical trial involving people with CVD and diabetes mellitus: a simulation study in the “Covid era” using the CVD‑COVID‑UK dataset

CCU075

Live - Data in Use

Impact of the COVID-19 pandemic on corticosteroid use and side effects in Takayasu arteritis and ANCA-associated vasculitis in England

CCU076

Live - Data in Use

The effect of COVID-19 infection on cardiovascular outcomes: an interaction analysis with environmental exposure

CCU077

Live - Data in Use

Risk assessment and long-term outcomes of acute coronary syndrome management strategy in cardio-oncology patients before and after the COVID-19 era

CCU078

On hold

Foresight: a generative artificial intelligence model of patient trajectories across the COVID-19 pandemic

CCU079

Live - Data in Use

Investigating the diagnoses of conditions among children in England following SARS-CoV-2 infections compared to general respiratory infections

CCU080

Live - Data in Use

Impact of COVID-19 on the use of cardiovascular imaging

CCU081

Live - Data in Use

Investigating the impact of COVID-19 on cardiovascular and thromboembolic events in idiopathic inflammatory myopathies and the incidence of connective tissue diseases

CCU082

Live - Data in Use

Pulmonary arterial hypertension in repaired congenital heart disease: impact of the COVID-19 pandemic on prevalence; late diagnosis; and outcomes

CCU083

Live - Data in Use

Trends in choice of management strategy for NSTE-ACS among patients with previous bypass surgery before and after the COVID-19 pandemic

CCU084

Live - Data in Use

Impact of COVID-19 on stroke incidence, severity, aetiology, management, and outcome in younger versus older individuals in England

CCU085

Live - Data in Use

STROKE-IMPACT: What are the long-term consequences of stroke on the patient and to the NHS, and how does COVID-19 contribute to variation?

CCU086

Live - Data in Use

A data landscape review of datasets used in the surveillance of neurological complications of COVID-19

CCU087

Live - Data in Use

The impact of COVID-19 on heart failure outcomes: the moderation roles of diabetes and obesity

CCU088

Live - Data in Use

The impact of COVID-19 on the management of iron deficiency, with or without anaemia, in primary and secondary care

CCU089

Live - Data in Use

The impact of comorbidity, socioeconomic status, and ethnicity on waiting times for surgery before and after the COVID-19 pandemic

CCU090

Live - Data in Use

The impact of cardiac rehabilitation following transcatheter aortic valve implantation before and after the COVID-19 pandemic

CCU092

Live - Data in Use

Simulation modelling of CVD development and management, identifying the extent to which COVID-19 has impacted on the assessment and treatment of CVD.

CCU093

Live - Data in Use

Understanding the relationship between diabetes and the development of multiple long-term conditions in England, Scotland, and Wales during and after the COVID-19 pandemic

CCU094

Live - Data in Use

Identifying preventative opportunities for coronary heart disease and stroke in multi-ethnic patients with non-cardiovascular conditions including COVID-19

CCU095

Live - Data in Use

Quantifying and mitigating bias and health inequalities induced by clinical risk models predicting COVID-19-related risks of people with CVD and diabetes.

CCU096

Live - Data in Use

Impact of COVID-19 on obesity and risks of cardio-renal-metabolic outcomes

CCU097

Live - Data in Use

Drivers, consequences and the COVID-19 pandemic’s effect on severe hyperglycaemia at type 2 diabetes diagnosis

CCU100

Live - Data in Use

Impact of COVID-19 on fatty liver disease and cardiovascular outcomes in England, across ethnicities and social deprivation

CCU101

Live - Data in Use

Lung-Pal-Equity: To identify patterns in use of hospital services in the last year of life for those with advanced lung disease and to examine inequalities by socio-economic group, including before, during and after the COVID-19 pandemic

The status of project CCU078 has been updated to reflect that NHS England paused the project on 29 May. Further detail on the projects is published on the British Heart Foundation Data Science Centre’s website.