Camelid TB Serology Quarterly Report: 1st October to 31st December 2014
Source: environment.data.gov.uk (2024-10-03)

Camelid TB Serology Quarterly Report. Camelid TB Serology Quarterly Report.

Camelid TB Serology
Report
1st October to 31st December 2014
Issued 09 September 2015

Submission Reason
Explanation
APHA /DEFRA
At Government expense
Parallet Test:
PAR-TB
TB breakdown herd with confirmed M. bovis infection (including Wales where Officially
TB Free Withdrawn [OTFW] status is determined on epidemiological grounds)
PAR-SUS
TB strongly suspected but not currently confirmed by laboratory culture – herd under
restrictions
PAR-TRC
Forward  tracing(s) from an M. bovis-infected camelid herd (includes camelid herds in
Wales only co-located on the same premises with infected cattle, sheep, deer, goats
& pigs)
Serial Test:
SER-CONT
Herd not under restriction but contiguous to a TB-infected herd
SER-COL
Herd not under restriction but co-located with an infected herd of cattle, deer, goats
etc. (Eng & Scot only)
SER-EPI
Herd not under restriction but TB tested due to an epidemiological link with a known
infected herd (e.g. back-tracing)
Commercial/Private
At Owner expense
SER-MVT
Pre- or post-movement test
SER-EXP 
Pre-export test
SER-DIAG
Diagnostic to exclude TB from a differential diagnoses in a herd not restricted (TB
strongly suspected)
SER-RHT
Monitoring - voluntary routine testing (herd nor restricted)
Camelid TB Serology Report 
Test Criteria
The camelid TB serology (antibody) test comprises two separate antibody tests in a test package that can be applied
flexibly to increase the sensitivity or specificity of the test as required, by using a parallel or serial test interpretation
respectively. The sensitivity and specificity values of combined antibody testing for camelids were described under AHVLA
Project FT1477 as follows (see also Rhodes et al., 2012);
Sensitivity = 81.3% [71.9-91.6]    [95% confidence intervals]
Specificity = 95.8% [93.3-98.2]
Parallel Test (e.g. confirmed breakdown herd test – for increased sensitivity):
Serial Test (e.g. movement test – for increased specificity):
Sensitivity = 55.8% [42.3-69.3]
Specificity = 99.7% 99.1-100]
N.B. The above combined test used by APHA from 1st October 2014 comprised the IDEXX ELISA and the Chembio
STAT-PAK lateral flow tests. Replacement of the STAT-PAK with the DPP VetTB lateral flow test by Chembio led to the
exchange of the STAT-PAK in the APHA camelid combined test with the new DPP VetTB test. APHA validation data
showed the DPP VetTB to have similar test specificities when used in the above combined test with the IDEXX ELISA
(Parallel 92.9% [89.6-96.2]; Serial 99.6% [98.7-100]). Preliminary data also suggested that the sensitivity of the DPP
VetTB is equivalent to that of the STAT-PAK.
Rhodes, S., Holder, T., Clifford, D., Dexter, I., Brewer, J., Smith, N., Waring, L., Crawshaw, T., Gillgan, S., Lyashchenko,
K., Lawrence, J., Clarke, J., de la Rua-Domenech, R., Vordermeier, M., 2012. Evaluation of gamma interferon and
antibody tuberculosis tests in alpacas. Clin Vaccine Immunol 19, 1677-1683.

Camelid TB Serology Report 
09 Sep 2015
Country
No.
Samples
Tested
England
109
Wales
53
Non GB
66
Total
228
Number of Samples tested and Submission Reason  1st Oct - 31st Dec 2014
Submission
Reason
No.
Samples
Tested
Parallel
PAR-SUS
53
PAR-TB
19
PAR-TRC
2
Parallel
Sum:
74
Serial
SER-COL
1
SER-CONT
87
Serial
Sum:
88
Commercial/Private Testing
SER-DIAG
19
SER-EXP
7
SER-MVT
15
SER-RHT
25
Commercial/Private Testing
Sum:
66
Total
Sum:
228

Camelid TB Serology Report 
09 Sep 2015
Submissions Received and Test Positivity 1st Oct - 31 Dec 2014
Country
Submission
Reason
No.
Submissions
No. Samples
Tested
No.
Positive
Samples
% Positive
Samples
England
Parallel
PAR-TB
1
19
5
26.3%
PAR-TRC
1
2
1
50.0%
Parallel
2
21
6
28.6%
Serial
SER-COL
1
1
0
0
SER-CONT
2
87
3
3.4%
Serial
3
88
3
3.4%
England Total
5
109
9
8.3%
Wales
Parallel
PAR-SUS
1
53
16
30.2%
Parallel
1
53
16
30.2%
Wales Total
1
53
16
30.2%
Non GB
Commercial/Private Testing
SER-DIAG
1
19
1
5.3%
SER-EXP
2
7
0
0
SER-MVT
1
15
0
0
SER-RHT
2
25
9
36.0%
Commercial/Private Testing
6
66
10
15.2%
Non GB Total
6
66
10
15.2%
Total
12
228
35
15.4 %
Test Positivity 1st Oct- 31st Dec 2014