Camelid TB Serology Quarterly Report: 1st July to 30th September 2022
Source: environment.data.gov.uk (2024-10-03)

Camelid TB Serology Quarterly Report. Camelid TB Serology Quarterly Report.

Camelid TB Serology
Quarterly Report
Number: 30
Report Period 1st July to 30th September 2022
Issued 05/Oct/2022

Submission Reason
Explanation
APHA /DEFRA
At Government expense
Parallel Test:
PAR-TB
TB breakdown herd with confirmed M. bovis infection (including Wales where Officially
TB Free Withdrawn [OTFW] status is determined on epidemiological grounds)
PAR-SUS
TB strongly suspected but not currently confirmed by laboratory culture – herd under
restrictions
PAR-TRC
Forward  tracing(s) from an M. bovis-infected camelid herd (includes camelid herds in
Wales only co-located on the same premises with infected cattle, sheep, deer, goats
& pigs)
PAR-COL-W
Wales only - camelids under restriction due to sharing a holding (colocation) with an
OTFW cattle herd or with other non-bovine animals affected by a culture-confirmed
incident
Serial Test:
SER-SUS (replaces PA
TB strongly suspected but not currently confirmed by laboratory culture – herd under
restrictions. If infection is confirmed the initial High Specificity (serial) test results can
be reinterpreted at High Sensitivity on request from the APHA case vet.
SER-CONT
Herd not under restriction but contiguous to a TB-infected herd
SER-COL
Herd not under restriction but co-located with an infected herd of cattle, deer, goats
etc. (Eng & Scot only)
SER-EPI
Herd not under restriction but TB tested due to an epidemiological link with a known
infected herd (e.g. back-tracing)
SER-CHK
Inconclusive Reactor check test – e.g. where private Enferplex test has produced a
2-spot-positive result on 2 consecutive occasions
Commercial/Private
At Owner expense
SER-MVT
Pre- or post-movement test
SER-EXP 
Pre-export test
SER-DIAG
Diagnostic to exclude TB from a differential diagnoses in a herd not restricted (TB
strongly suspected)
SER-RHT
Monitoring - voluntary routine testing (herd nor restricted)
Quarterly Camelid Serology Report
Test Criteria
The camelid TB serology (antibody) test generally comprises two separate antibody tests in a test package that can be
applied flexibly to increase the sensitivity or specificity of the test as required, by using a parallel or serial test
interpretation respectively. The sensitivity and specificity values of combined antibody testing for camelids were described
under AHVLA Project FT1477 (see Rhodes et al., 2012) and re-assessed in May 2018 to show the following test
performance;
IDEXX /DPP VetTB
ENFER 2-SPOT/DPP VetTB
IDEXX/ENFER 2-SPOT
% Se
74
71
75
95% C.I.
65.4-82.6
62.1-79.9
66.5-83.5
% Sp
96
96.7
97.3
95% C.I.
93.8-98.2
95.8-99.4
95.4-99.1
Fishers Exact [2-sided] test showed no significant difference in sensitivity or specificity between any of these three test options.
Table 2 – High Specificity / Serial test options:
Table 1 – High Sensitivity / Parallel test options:
Fishers Exact [2-sided] test showed no significant difference in test sensitivity or specificity between these two test options.
ENFER 4-SPOT
IDEXX/DPP VetTB
% Se
60
56
95% C.I.
50.4-69.9
46.3-65.7
% Sp
99.66
100
95% C.I.
98.9-100
Rhodes, S., Holder, T., Clifford, D., Dexter, I., Brewer, J., Smith, N., Waring, L., Crawshaw, T., Gillgan, S., Lyashchenko,
K., Lawrence, J., Clarke, J., de la Rua-Domenech, R., Vordermeier, M., 2012. Evaluation of gamma interferon and
antibody tuberculosis tests in alpacas. Clin Vaccine Immunol 19, 1677-1683.

Quarterly Camelid Serology Report
05 Oct 2022
Table 1a
Country
No.
Samples
Tested
England
123
Wales
26
Total for Q3
149
Number of Samples tested and Submission Reason  2022 Q3 (July - September)
Table 1b
Submission
Reason
No. Samples
Tested
Serial
SER-CONT
75
Serial
Sum:
75
Commercial/Private Testing
SER-MVT
2
Commercial/Private Testing
Sum:
2
SER-SUS
72
Sum:
72
Total for Q3
Sum:
149

Quarterly Camelid Serology Report
05 Oct 2022
Table 2a
Country
No.
Samples
Tested
England
541
Wales
84
Non GB
5
Total for Q3
630
Number of Samples tested and Submission Reason 2022 up to end of Q3 (January - September)
Table 2b
APHA/DEFRA
Submission
Reason
No.
Samples
Tested
Parallel
PAR-TB
67
PAR-TRC
15
Parallel
Sum:
82
Serial
SER-CONT
299
Serial
Sum:
299
Commercial/Private Testing
SER-DIAG
7
SER-MVT
17
SER-RHT
2
Commercial/Private Testing
Sum:
26
SER-SUS
223
Sum:
223
Total for 2022 up to end
of Q3
630

Quarterly Camelid Serology Report
05 Oct 2022
Table 3a
Submissions Received and Test Positivity in 2022 Q3
Country
Submission
Reason
No.
Submissions
No. Samples
Tested
No.
Positive
Samples
% Positive
Samples
England
Serial
SER-CONT
7
49
1
2.0%
Serial
7
49
1
2.0%
Commercial/Private Testing
SER-MVT
2
2
0
0
Commercial/Private Testing
2
2
0
0
SER-SUS
2
72
0
0
2
72
0
0
England Total
11
123
1
0.8%
Wales
Serial
SER-CONT
3
26
0
0
Serial
3
26
0
0
Wales Total
3
26
0
0
Totals for Q3
14
149
1
0.7 %
Test Positivity in 2022 Q3 (July - September)

Quarterly Camelid Serology Report
05 Oct 2022
Table 3b
Submissions Received and Test Positivity in 2022 up to the end of Q3
Country
Submission
Reason
No.
Submissions
No. Samples
Tested
No.
Positive
Samples
% Positive
Samples
England
Parallel
PAR-TB
2
67
6
9.0%
PAR-TRC
2
4
0
0
Parallel
4
71
6
8.5%
Serial
SER-CONT
21
268
8
3.0%
Serial
21
268
8
3.0%
Commercial/Private Testing
SER-DIAG
2
7
0
0
SER-MVT
4
12
0
0
SER-RHT
1
2
0
0
Commercial/Private Testing
7
21
0
0
SER-SUS
4
181
8
4.4%
4
181
8
4.4%
England Total
36
541
22
4.1%
Wales
Parallel
PAR-TRC
1
11
0
0
Parallel
1
11
0
0
Serial
SER-CONT
5
31
0
0
Serial
5
31
0
0
SER-SUS
2
42
0
0
2
42
0
0
Wales Total
8
84
0
0
Non GB
Commercial/Private Testing
SER-MVT
1
5
0
0
Commercial/Private Testing
1
5
0
0
Non GB Total
1
5
0
0
Totals up to
end Q3
45
630
22
3.5 %
Test Positivity in 2022 up to end of Q3 (January - September)

Quarterly Camelid Serology Report
05 Oct 2022
Submissions Received in 2022 up to end of Q3
Analysis
Analysis Description
Q1
No.
samples
tested
Q2
No.
samples
tested
Q3
No.
samples
tested
Totals up to end Q3
TC0503
Camelid TB Enferplex - 2
Spot
2
67
69
TC0603
Camelid TB Enferplex - 4
Spot
291
99
390
TC0611
Chembio DPP VetTB lateral
flow rapid antibody test
128
31
50
209
TC0867
Camelid TB Antibody
ELISA
92
98
50
240
Table 4: Number of samples Tested by Test Code