Camelid TB Serology Quarterly Report: 1st July to 30th September 2019
Source: environment.data.gov.uk (2024-10-03)

Camelid TB Serology Quarterly Report. Camelid TB Serology Quarterly Report.

Camelid TB Serology
Quarterly Report
Number: 18
Report Period 1st July to 30th September 2019
Issued 02 October 2019

Submission Reason
Explanation
APHA /DEFRA
At Government expense
Parallel Test:
PAR-TB
TB breakdown herd with confirmed M. bovis infection (including Wales where Officially
TB Free Withdrawn [OTFW] status is determined on epidemiological grounds)
PAR-SUS
TB strongly suspected but not currently confirmed by laboratory culture – herd under
restrictions
PAR-TRC
Forward  tracing(s) from an M. bovis-infected camelid herd (includes camelid herds in
Wales only co-located on the same premises with infected cattle, sheep, deer, goats
& pigs)
Serial Test:
SER-CONT
Herd not under restriction but contiguous to a TB-infected herd
SER-COL
Herd not under restriction but co-located with an infected herd of cattle, deer, goats
etc. (Eng & Scot only)
SER-EPI
Herd not under restriction but TB tested due to an epidemiological link with a known
infected herd (e.g. back-tracing)
Commercial/Private
At Owner expense
SER-MVT
Pre- or post-movement test
SER-EXP 
Pre-export test
SER-DIAG
Diagnostic to exclude TB from a differential diagnoses in a herd not restricted (TB
strongly suspected)
SER-RHT
Monitoring - voluntary routine testing (herd nor restricted)
Quarterly Camelid Serology Report
Test Criteria
The camelid TB serology (antibody) test generally comprises two separate antibody tests in a test package that can be
applied flexibly to increase the sensitivity or specificity of the test as required, by using a parallel or serial test
interpretation respectively. The sensitivity and specificity values of combined antibody testing for camelids were described
under AHVLA Project FT1477 (see Rhodes et al., 2012) and re-assessed in May 2018 to show the following test
performance;
Table 1 – High Sensitivity / Parallel test options:
IDEXX /DPP VetTB
ENFER 2-SPOT/DPP VetTB
IDEXX/ENFER 2-SPOT
% Se
74
71
75
95% C.I.
65.4-82.6
62.1-79.9
66.5-83.5
% Sp
96
96.7
97.3
95% C.I.
93.8-98.2
95.8-99.4
95.4-99.1
Fishers Exact [2-sided] test showed no significant difference in sensitivity or specificity between any of these three test options.
Table 2 – High Specificity / Serial test options:
Fishers Exact [2-sided] test showed no significant difference in test sensitivity or specificity between these two test options.
ENFER 4-SPOT
IDEXX/DPP VetTB
% Se
60
56
95% C.I.
50.4-69.9
46.3-65.7
% Sp
99.66
100
95% C.I.
98.9-100
Rhodes, S., Holder, T., Clifford, D., Dexter, I., Brewer, J., Smith, N., Waring, L., Crawshaw, T., Gillgan, S., Lyashchenko,
K., Lawrence, J., Clarke, J., de la Rua-Domenech, R., Vordermeier, M., 2012. Evaluation of gamma interferon and
antibody tuberculosis tests in alpacas. Clin Vaccine Immunol 19, 1677-1683.

Quarterly Camelid Serology Report
02 Oct 2019
Table 1a
Country
No.
Samples
Tested
England
860
Wales
73
Total for Q3
933
Number of Samples tested and Submission Reason  2019 Q3 (July - September)
Table 1b
Submission
Reason
No.
Samples
Tested
Parallel
PAR-SUS
562
PAR-TB
7
PAR-TRC
32
Parallel
Sum:
601
Serial
SER-COL
86
SER-CONT
208
SER-EPI
1
Serial
Sum:
295
Commercial/Private Testing SER-DIAG
1
SER-EXP
8
SER-MVT
15
SER-RHT
9
Commercial/Private Testin
Sum:
33
                   
4
Sum:
4
Total for Q3
Sum:
933

Quarterly Camelid Serology Report
02 Oct 2019
Table 2a
Country
No.
Samples
Tested
England
2063
Wales
176
Non GB
2
Total for Q3
2241
Number of Samples tested and Submission Reason 2019 up to end of Q3 (January - September)
Table 2b
APHA/DEFRA
Submission
Reason
No.
Samples
Tested
Parallel
PAR-SUS
1126
PAR-TB
69
PAR-TRC
48
Parallel
Sum:
1243
Serial
SER-COL
156
SER-CONT
766
SER-EPI
2
Serial
Sum:
924
Commercial/Private Testing
SER-DIAG
1
SER-EXP
15
SER-MVT
41
SER-RHT
13
Commercial/Private Testing
Sum:
70
                   
4
Sum:
4
Total for 2019 up to end
of Q3
2241

Quarterly Camelid Serology Report
02 Oct 2019
Table 3a
Submissions Received and Test Positivity in 2019 Q3
Country
Submission
Reason
No.
Submissions
No. Samples
Tested
No.
Positive
Samples
% Positive
Samples
England
Parallel
PAR-SUS
2
561
36
6.4%
PAR-TB
2
7
1
14.3%
PAR-TRC
10
22
2
9.1%
Parallel
14
590
39
6.6%
Serial
SER-COL
4
86
0
0
SER-CONT
31
146
9
6.2%
SER-EPI
1
1
0
0
Serial
36
233
9
3.9%
Commercial/Private Testing
SER-DIAG
1
1
0
0
SER-EXP
1
8
0
0
SER-MVT
4
15
0
0
SER-RHT
2
9
0
0
Commercial/Private Testing
8
33
0
0
                   
1
4
0
0
1
4
0
0
England Total
59
860
48
5.6%
Wales
Parallel
PAR-SUS
1
1
0
0
PAR-TRC
1
10
0
0
Parallel
2
11
0
0
Serial
SER-CONT
3
62
3
4.8%
Serial
3
62
3
4.8%
Wales Total
5
73
3
4.1%
Totals for Q3
64
933
51
5.5 %
Test Positivity in 2019 Q3 (July - September)

Quarterly Camelid Serology Report
02 Oct 2019
Table 3b
Submissions Received and Test Positivity in 2019 up to the end of Q3
Country
Submission
Reason
No.
Submissions
No. Samples
Tested
No.
Positive
Samples
% Positive
Samples
England
Parallel
PAR-SUS
5
1,125
52
4.6%
PAR-TB
3
27
1
3.7%
PAR-TRC
14
36
2
5.6%
Parallel
22
1,188
55
4.6%
Serial
SER-COL
11
152
1
0.7%
SER-CONT
93
650
20
3.1%
SER-EPI
1
1
0
0
Serial
105
803
21
2.6%
Commercial/Private Testing
SER-DIAG
1
1
0
0
SER-EXP
2
15
0
0
SER-MVT
10
39
0
0
SER-RHT
4
13
0
0
Commercial/Private Testing
17
68
0
0
                   
1
4
0
0
1
4
0
0
England Total
145
2,063
76
3.7%
Wales
Parallel
PAR-SUS
1
1
0
0
PAR-TB
1
42
0
0
PAR-TRC
2
12
0
0
Parallel
4
55
0
0
Serial
SER-COL
2
4
0
0
SER-CONT
15
116
3
2.6%
SER-EPI
1
1
0
0
Serial
18
121
3
2.5%
Wales Total
22
176
3
1.7%
Non GB
Commercial/Private Testing
SER-MVT
1
2
0
0
Commercial/Private Testing
1
2
0
0
Non GB Total
1
2
0
0
Totals up to
end Q3
168
2,241
79
3.5 %
Test Positivity in 2019 up to end of Q3 (January - September)

Quarterly Camelid Serology Report
02 Oct 2019
Submissions Received in 2019 up to end of Q3
Analysis
Analysis Description
Q1
No.
samples
tested
Q2
No.
samples
tested
Q3
No.
samples
tested
Totals up to end Q3
TC0503
Camelid TB Enferplex - 2
Spot
175
422
588
1,185
TC0603
Camelid TB Enferplex - 4
Spot
244
193
207
644
TC0615
Camelid TB DPP VetTB
antibody test
312
559
39
910
TC0867
Camelid TB Antibody
ELISA
137
137
138
412
Table 4: Number of samples Tested by Test Code