Camelid TB Serology Quarterly Report: 1st October to 31st December 2019
Source: environment.data.gov.uk (2024-10-03)

Camelid TB Serology Quarterly Report. Camelid TB Serology Quarterly Report.

Camelid TB Serology
Quarterly Report
Number: 19
Report Period 1st October to 31st December 2019
Issued 14 January 2020

Submission Reason
Explanation
APHA /DEFRA
At Government expense
Parallel Test:
PAR-TB
TB breakdown herd with confirmed M. bovis infection (including Wales where Officially
TB Free Withdrawn [OTFW] status is determined on epidemiological grounds)
PAR-SUS
TB strongly suspected but not currently confirmed by laboratory culture – herd under
restrictions
PAR-TRC
Forward  tracing(s) from an M. bovis-infected camelid herd (includes camelid herds in
Wales only co-located on the same premises with infected cattle, sheep, deer, goats
& pigs)
Serial Test:
SER-CONT
Herd not under restriction but contiguous to a TB-infected herd
SER-COL
Herd not under restriction but co-located with an infected herd of cattle, deer, goats
etc. (Eng & Scot only)
SER-EPI
Herd not under restriction but TB tested due to an epidemiological link with a known
infected herd (e.g. back-tracing)
Commercial/Private
At Owner expense
SER-MVT
Pre- or post-movement test
SER-EXP 
Pre-export test
SER-DIAG
Diagnostic to exclude TB from a differential diagnoses in a herd not restricted (TB
strongly suspected)
SER-RHT
Monitoring - voluntary routine testing (herd nor restricted)
Quarterly Camelid Serology Report
Test Criteria
The camelid TB serology (antibody) test generally comprises two separate antibody tests in a test package that can be
applied flexibly to increase the sensitivity or specificity of the test as required, by using a parallel or serial test
interpretation respectively. The sensitivity and specificity values of combined antibody testing for camelids were described
under AHVLA Project FT1477 (see Rhodes et al., 2012) and re-assessed in May 2018 to show the following test
performance;
Table 1 – High Sensitivity / Parallel test options:
IDEXX /DPP VetTB
ENFER 2-SPOT/DPP VetTB
IDEXX/ENFER 2-SPOT
% Se
74
71
75
95% C.I.
65.4-82.6
62.1-79.9
66.5-83.5
% Sp
96
96.7
97.3
95% C.I.
93.8-98.2
95.8-99.4
95.4-99.1
Fishers Exact [2-sided] test showed no significant difference in sensitivity or specificity between any of these three test options.
Table 2 – High Specificity / Serial test options:
Fishers Exact [2-sided] test showed no significant difference in test sensitivity or specificity between these two test options.
ENFER 4-SPOT
IDEXX/DPP VetTB
% Se
60
56
95% C.I.
50.4-69.9
46.3-65.7
% Sp
99.66
100
95% C.I.
98.9-100
Rhodes, S., Holder, T., Clifford, D., Dexter, I., Brewer, J., Smith, N., Waring, L., Crawshaw, T., Gillgan, S., Lyashchenko,
K., Lawrence, J., Clarke, J., de la Rua-Domenech, R., Vordermeier, M., 2012. Evaluation of gamma interferon and
antibody tuberculosis tests in alpacas. Clin Vaccine Immunol 19, 1677-1683.

Quarterly Camelid Serology Report
14 Jan 2020
Table 1a
Country
No.
Samples
Tested
England
976
Wales
42
Scotland
1
Total for Q4
1019
Number of Samples tested and Submission Reason  2019 Q4 (October - December)
Table 1b
Submission
Reason
No. Samples
Tested
Parallel
PAR-SUS
91
PAR-TB
548
PAR-TRC
7
Parallel
Sum:
646
Serial
SER-COL
10
SER-CONT
346
SER-EPI
1
Serial
Sum:
357
Commercial/Private Testing
SER-MVT
15
Commercial/Private Testing
Sum:
15
SER-CHK
1
Sum:
1
Total for Q4
Sum:
1019

Quarterly Camelid Serology Report
14 Jan 2020
Table 2a
Country
No.
Samples
Tested
England
3039
Wales
218
Non GB
2
Scotland
1
Total for Q4
3260
Number of Samples tested and Submission Reason 2019 up to end of Q4 (January - December)
Table 2b
APHA/DEFRA
Submission
Reason
No.
Samples
Tested
Parallel
PAR-SUS
501
PAR-TB
1333
PAR-TRC
55
Parallel
Sum:
1889
Serial
SER-COL
166
SER-CONT
1115
SER-EPI
2
Serial
Sum:
1283
Commercial/Private Testing
SER-DIAG
1
SER-EXP
15
SER-MVT
56
SER-RHT
13
Commercial/Private Testing
Sum:
85
SER-CHK
3
Sum:
3
Total for 2019 up to end
of Q4
3260

Quarterly Camelid Serology Report
14 Jan 2020
Table 3a
Submissions Received and Test Positivity in 2019 Q4
Country
Submission
Reason
No.
Submissions
No. Samples
Tested
No.
Positive
Samples
% Positive
Samples
England
Parallel
PAR-SUS
3
91
5
5.5%
PAR-TB
5
548
80
14.6%
PAR-TRC
1
2
0
0
Parallel
9
641
85
13.3%
Serial
SER-COL
5
10
0
0
SER-CONT
20
310
5
1.6%
Serial
25
320
5
1.6%
Commercial/Private Testing
SER-MVT
6
15
0
0
Commercial/Private Testing
6
15
0
0
England Total
40
976
90
9.2%
Wales
Parallel
PAR-TRC
2
5
0
0
Parallel
2
5
0
0
Serial
SER-CONT
6
36
0
0
SER-EPI
1
1
0
0
Serial
7
37
0
0
Wales Total
9
42
0
0
Scotland
SER-CHK
1
1
0
0
1
1
0
0
Scotland Total
1
1
0
0
Totals for Q4
50
1,019
90
8.8 %
Test Positivity in 2019 Q4 (October - December)

Quarterly Camelid Serology Report
14 Jan 2020
Table 3b
Submissions Received and Test Positivity in 2019 up to the end of Q4
Country
Submission
Reason
No.
Submissions
No. Samples
Tested
No.
Positive
Samples
% Positive
Samples
England
Parallel
PAR-SUS
5
500
20
4.0%
PAR-TB
11
1,291
118
9.1%
PAR-TRC
15
38
2
5.3%
Parallel
31
1,829
140
7.7%
Serial
SER-COL
16
162
1
0.6%
SER-CONT
113
963
25
2.6%
Serial
129
1,125
26
2.3%
Commercial/Private Testing
SER-DIAG
1
1
0
0
SER-EXP
2
15
0
0
SER-MVT
16
54
0
0
SER-RHT
4
13
0
0
Commercial/Private Testing
23
83
0
0
SER-CHK
2
2
0
0
2
2
0
0
England Total
185
3,039
166
5.5%
Wales
Parallel
PAR-SUS
1
1
0
0
PAR-TB
1
42
0
0
PAR-TRC
4
17
0
0
Parallel
6
60
0
0
Serial
SER-COL
2
4
0
0
SER-CONT
21
152
3
2.0%
SER-EPI
2
2
0
0
Serial
25
158
3
1.9%
Wales Total
31
218
3
1.4%
Non GB
Commercial/Private Testing
SER-MVT
1
2
0
0
Commercial/Private Testing
1
2
0
0
Non GB Total
1
2
0
0
Scotland
SER-CHK
1
1
0
0
1
1
0
0
Scotland Total
1
1
0
0
Totals up to
end Q4
218
3,260
169
5.2 %
Test Positivity in 2019 up to end of Q4 (January - December)

Quarterly Camelid Serology Report
14 Jan 2020
Submissions Received in 2019 up to end of Q4
Analysis
Analysis Description
Q1
No.
samples
tested
Q2
No.
samples
tested
Q3
No.
samples
tested
Q4
No.
samples
tested
Totals up to end Q4
TC0503
Camelid TB Enferplex - 2
Spot
175
422
588
636
1,821
TC0603
Camelid TB Enferplex - 4
Spot
244
193
207
276
920
TC0611
Dhembio DPP VetTB lateral
flow rapid antibody test
687
112
799
TC0615
Camelid TB DPP VetTB
antibody test
312
559
39
910
TC0867
Camelid TB Antibody
ELISA
137
137
138
738
1,150
Table 4: Number of samples Tested by Test Code