酒井清孝
酒井 清孝
酒井 清孝(さかい きよたか、1941年6月26日 - )は、日本の理工学者。
現在は早稲田大学名誉教授、公益財団法人松籟科学技術振興財団理事、医療法人社団善仁会Gr顧問、人工臓器歴史遺産研究会代表である。
化学工学を中心とした医療工学の研究を行い、人工臓器の開発や設計に携わった。生命維持管理装置の操作・設計に化学工学の知識を生かして、現代の高度先進医療を支える医療工学の発展を促進した研究者である。生命維持管理装置を扱う臨床工学技士、医学に関わる理工学研究者、人工臓器を扱う医師とともに研究を行い、多くの業績を残している。
秋山敏、林寛、穂坂英明、横山真喜男、峰島三千男、安住利恵子、小沢治子、鶴岡秀志、竹澤真吾、松田兼一、山下明泰、小澤喜久夫、金森敏幸、金武潤、吉田亮、櫛谷文彦、阪上正裕、柳沢真澄、吉見靖男、桜井公美、小久保謙一、福田誠、氷見直之、宮坂武寛、薬師寺大二、青柳里果、松田範昭、小林純、荏原充宏、熊代善一、長瀬健一、葉山順代、山本健一郎、井戸田直和、小川武人、岩永進太郎、長谷川麗、小松寛、阪田宏樹、滑川亘希、井上幹康などの理工学研究者、企業経営者、企業技術者、医学研究者、医師を育てた。
1965年 早稲田大学理工学部応用化学科卒
1967年 同大学院理工学研究科応用化学専攻修士課程修了(工学修士)
1970年 同大学院理工学研究科応用化学専攻博士課程修了 (工学博士)(城塚正教授指導)
1970年 静岡大学工学部化学工学科専任講師(文部教官教育職)
1972年 同助教授(文部教官教育職)
1973年 早稲田大学理工学部応用化学科助教授
1978年 同教授
2007年 早稲田大学先進理工学部応用化学科教授
2012年 早稲田大学名誉教授
クリーブランドクリニック人工臓器研究所客員教授、テキサス大学客員研究員、静岡大学・大阪市立大学・芝浦工業大学・東京農工大学・横浜国立大学・東京大学・東北大学・名古屋大学・東京女子医科大学・千葉大学・東京電機大学の非常勤講師を歴任
日本エアデールテリア協会元理事長、元審査員
Honorary Editorial Board Member: Journal of Artificial Organs
AIChE (American Institute of Chemical Engineers) Senior Member
ASAIO (American Society for Artificial Organs) Member
EDTA (European Dialysis and Transplantation Association) Senior Member
NAMS (North American Membrane Society) Senior Member
1965年 早稲田応用化学会小林賞
1981年 化学工学会関東支部功労賞
1992年 化学工学会研究賞
1994年 日本医科器械学会著述賞
1995年、1997年、1998年、2001年、2006年、2009年、2010年 日本人工臓器学会論文賞
1998年 化学工学会学会賞
1998年 化学工学会池田亀三郎記念賞
2011年 公益財団法人日本腎臓財団功労賞
2018年 日本生体医工学会論文賞・阪本賞
2021年 春の叙勲・瑞宝中綬章
Fukuda M, Furuya T, Sadano K, et al: Electron microscopic confirmation of anisotropic pore characteristics for ECMO membranes theoretically validating the risk of SARS-CoV-2 permeation. Membranes, July 2021
Fukuda M, Tokumine A, Noda K, et al: Newly developed pediatric membrane oxygenator that suppresses excessive pressure drop in cardiopulmonary bypass and extracorporeal membrane oxygenation (ECMO). Membranes, 10, 362, 2020; doi:10.3390/membranes10110362
Fukuda M, Yoshimoto H, Saomoto H, et al: Validity of three-dimensional tortuous pore structure and fouling of hemoconcentration capillary membrane using the tortuous pore diffusion model and scanning probe microscopy. Membranes, 10, 315, 2020; doi:10.3390/membranes10110315
Fukuda M, Saomoto H, Mori T, et al: Impact of three-dimensional tortuous pore structure on polyethersulfone membrane morphology and mass transfer properties from a manufacturing perspective. J Artif Organs, 23, 171-179, 2019, https://doi.org/10.1007/s10047-019-01144-0
Komatsu H, Sakai K, Baba T, et al: Aggregation behavior of short-chained archaeal phospholipid analogs: Contribution of methyl branches to lipid hydrophobicity and membrane formability. Colloid and Interface Science Communications, 32, 100200, 2019
Fukuda M, Saomoto H, Shimizu T, et al: Obsevation and proposed measurement of three-dimensional tortuous capillary pores with depth for hollow fiber hemoconcentrator membrane using dynamic force microscopy. Adv Biomed Eng 8, 145-152, 2019
Fukuda M, Yoshimura K, Namekawa K, et al: Technical characterization of dialysis fluid flow and mass transfer rate in dialyzers with various filtration coefficients using dimensionless correlation equation. J Artif Organs, 20, 145-151, 2017
Fukuda M, Namekawa K, Sakai K: Identical dependence of dialysate-side mass transfer coefficient on Reynolds number using dimensionless correlation based on the mass transfer model in newly developed dialyzers and a downsized dialyzer. Adv Biomed Eng 5, 118-123, 2016
Fukuda M, Yamamoto K, Maeda K, Sakai K: Dependence of roller pump rotation on blood backflow and simple estimation of negative pressure required for blood withdrawal using backflow volume measurement at the arterial side-chamber inlet. Therapeutics and Engineering, 27, 21-28, 2015
Yamazaki K, Yakushiji T,  Sakai K: Nanoscale analysis of hydrophilicity-hydrophobicity distribution on inner surfaces of wet dialysis membranes by atomic force microscopy. J Membr Sci 396, 38-42, 2012
Akimoto J Nakayama M, Sakai K, et al: Synthesis of terminal-functionalized thermoresponsive diblock copolymers using biogradable macro-RAFT agents. Polymer J 45, 233-237, 2012
Namekawa K, Matsuda M, Fukuda M, et al: Poly(N-vinyl-2-pyrrolidone) elution from polysulfone dialysis membrane by varying solvent and wall shear stress. J Artif Organs 15, 185-192, 2012
Hirano A, Kida S, Yamamoto K, et al: Experimental evaluation of flow and dialysis performance of hollow-fiber dialyzers with different packing densities. J Artif Organs 15, 168-175, 2012
Sakai K, Matsuda M: Solute removal efficiency and biocompatibility of the high-performance membrane - from engineering points of view. pp.11-22, in High-Performance Membrane Dialyzers ed by Saito A, Kawanishi H, Yamashita AC, et al, Contributions to Nephrology, Vol.173, 2011
Matsuda M, Yakushiji T, Sakai K: Effect of γ irradiation on the surface properties of wet polysulfone films containing poly(vinylpyrrolidone). Surf Interface Anal 43, 976-983, 2011
Idota N, Kikuchi A, Kobayashi J, et al: Modulation of graft architectures for enhancing hydrophobic interaction of biomolecules with thermoresponsive polymer-grafted surfaces. Colloids and Surfaces B: Biointerfaces 99, 95-101, 2011
Namekawa K, Kaneko A, Sakai K, et al: Longer storage of dialyzers increases elution of poly(N-vinyl-2-pyrrolidone) from polysulfone-group dialysis membranes. J Artif Organs 14, 52-57, 2011
Yamazaki K, Matsuda M, Yamamoto K, et al: Internal and surface structure characterization of cellulose triacetate hollow-fiber dialysis membranes. J Membr Sci 368, 34-40, 2011
Koga S, Yakushiji T, Matsuda M, et al: Functional-group analysis of polyvinylpyrrolidone on the inner surface of hollow-fiber dialysis membranes, by near-field infrared microspectroscopy. J Membr Sci 355, 208-213, 2010
Hirano A, Yamamoto K, Matsuda M, et al: Evaluation of dialyzer jacket structure and hollow-fiber dialysis membranes to achieve high dialysis performance. Ther Apher Dial 15, 66-74, 2010
Aoyagi S, Namekawa K, Yamamoto K, et al: Investigation of molecular surfaces with time-of-light secondary ion mass spectrometry. Surf Interface Anal 42, 1593-1597, 2010
Akimoto J, Nakayama M, Sakai K, et al: Thermally controlled intracellular uptake system of polymeric micelles possessing poly(N-isopropylamide)-based outer coronas. Mol Pharm 7, 926-935, 2010
Yamamoto K, Ogawa T, Matsuda M, et al: Membrane potential and charge density of hollow-fiber dialysis membrane. J Membr Sci 355, 182-185, 2010
Ogawa T, Koga S, Yakushiji T, et al: Development of device for chemiluminescence determination of superoxide generated inside a dialysis hollow-fiber membrane. J Artif Organs 13, 58-62, 2010
Namekawa K, Fukuda M, Matsuda M, et al: Nanotechnological characterization of human albumin adsorption on wet synthetic polymer dialysis membrane surfaces. ASAIO J 55, 236-242, 2009
Yoshimi Y, Narimatsu A, Nakayama K, et al: Development of an enzyme-free glucose sensor using the gate effect of a molecularly imprinted polymer. J Artif Organs 12, 264-270, 2009
Ogawa T, Aoyagi S, Miyasaka T, et al: Fluorescence enhancement of fluorescent isothiocyanate-labeled protein A caused by affinity binding with immunoglobulin G in bovine plasma. Sensors 9, 8271-8277, 2009
Akimoto J, Nakayama M, Sakai K, et al: Temperature-induced intracellular uptake of thermoresponsive polymeric micelles. Biomacromolecules 10, 1331-1336, 2009
Yamamoto K, Matsuda M, Hirano A, et al: Computational evaluation of dialysis fluid flow in dialyzers with variously designed jackets. Artif Organs 33, 481-486, 2009
Hirano A, Yamamoto K, Matsuda M, et al: Flow uniformity in oxygenators with different outlet port design. ASAIOJ 55, 209-212, 2009
Kunikata S, Fukuda M, Yamamoto K, et al: Technical characterization of dialysis fluid flow of newly developed dialyzers using mass transfer correlation equation. ASAIO J 55, 231-235, 2009
Sugiura S, Imano W, Takagi T et al: Thermoresponsive protein adsorption of poly(N-isopropylacrylamide)-modified streptavidin on polydimethylsiloxane microchannel surfaces. Biosens Bioelectron 24, 1135-1140, 2009
Matsuda M, Yamamoto K, Yakushiji T, et al: Nanotechnological evaluation of protein adsorption on dialysis membrane surface hydrophilized with polyvinylpyrrolidone. J Membr Sci 310, 219-228, 2008
Ebara M, Yamato M, Aoyagi T, et al: A novel approach to observing synergy effects of PHSRN on integrin-RGD binding using intelligent surfaces. Adv Mater 20, 3034-3038, 2008
Ebara M, Yamato M, Aoyagi T, et al: The effect of extensible PEG tethers on shielding between grafted thermo-responsive polymer chains and integrin-RGD binding. Biomaterials 29, 3650-3655, 2008
Akimoto J, Nakayama M, Sakai K, et al: Molecular design of outermost surface functionalized thermo-responsive polymeric micelles with biodegradable cores. J Polym Sci 46, 7127-7137, 2008
Matsuda M, Sato M, Sakata H, et al: Effects of fluid flow on elution of hydrophilic modifier from dialysis membrane surfaces. J Artif Organs 11, 148-155, 2008
Yamamoto K, Hayama M, Matsuda T, et al: Evaluation of asymmetrical structure dialysis membrane by tortuous capillary pore diffusion model. J Membr Sci 287, 88-93, 2007
Ogawa T, Shimazaki H, Aoyagi S, et al: Electrical oscillation at a water/octanol interface in a hydrophobic container. J Colloid Interface Sci 305, 195-197, 2007
Yamamoto K, Matsukawa H, Yakushiji T, et al: Technical evaluation of dialysate flow in a newly designed dialyzer. ASAIO J, 53, 36-40, 2007
Yamamoto K, Matsuda M, Okuoka M, et al: Antioxidation property of vitamin E-coated polysulfone dialysis membrane and recovery of oxidized vitamin E by vitamin C treatment. J Membr Sci 302, 115-118, 2007
Nakayama M, Chung JE, Miyazaki T, et al: Thermal modulation of intracellular drug distribution using thermoresponsive polymeric micelles. React Funct Polym 67, 1398-1407, 2007
Sekine S, Watanabe Y, Yoshimi Y, et al: Influence of solvents on chiral discriminative gate effect of moleculary imprinted poly(ethylene glycol dimethacrylate-co-methacrylic acid). Sens Actuators B 127, 512-517, 2007
Yamamoto K, Matsuda M, Hayama M, et al: Evaluation of the activity of endotoxin trapped by a hollow-fiber dialysis membrane. J Membr Sci 272, 211-216, 2006
Idota N, Kikuchi A, Kobayashi J, et al: Thermal modulated interaction of aqueous steroids using polymer-grafted capillaries. Langmuir 22, 425-430, 2006
Miyasaka T, Endo K, Mochizuki S, et al: Superoxide sensors. Sens Lett 4, 144-154, 2006
Nakamura M, Okano T, Miyazaki T, et al: Molecular design of biodegradable polymeric micelles for temperature-responsive drug release. J Control Release 115, 46-56, 2006
Ogawa T, Shimazaki H, Aoyagi S, et al: Novel modeling of electrical potential oscillation across a water/octanol/water liquid membrane. J Membr Sci 285, 120-125, 2006
Nagase K, Hasegawa U, Kohori F, et al: The photoresponse of a molybdenum porphyrin makes an artificial gill feasible. J Membr Sci 249, 235-243, 2005
Iwanaga S, Akiyama S, Kikuchi A, et al: Fabrication of a cell array on ultrathin hydrophilic polymer gels utilizing electron beam irradiation and UV excimer laser ablation. Biomaterials 26, 5395-5404, 2005
Nagase K, Kohori F, Sakai K, et al: Rearrangement of hollow fibers for enhancing oxygen transfer in an artificial gill using oxygen carrier solution. J Membr Sci 254, 207-217, 2005
Nagase K, Kohori F, Sakai K: Oxygen transfer performance of a membrane oxygenator composed of crossed and parallel hollow fibers. Biochem Eng J 24, 105-113, 2005
Yamamoto K, Hiwatari M, Kohori F, et al: Membrane fouling and dialysate flow pattern in an internal filtration-enhancing dialyzer. J Artif Organs 8, 198-205, 2005
Idota N, Kikuchi A, Kobayashi J, et al: Microfluidic valves comprising nanolayered thermoresponsive polymer-grafted capillaries. Adv Mater 17, 2723-2727, 2005
Yamamoto K, Kobayashi K, Endo K, et al: Hollow-fiber blood-dialysis membranes: superoxide generation, permeation and dismutation measured by chemiluminescence. J Artif Organs 8, 257-262, 2005