上田実 (医学研究者)
Al-Sharabi N, Xue Y, Fujio M, Ueda M, Gjerde C, Mustafa K, Fristad I.Bone marrow stromal cell paracrine factors direct osteo/odontogenic differentiation of dental pulp cells.Tissue Eng Part A. 20(21-22): 3063-72, 2014
Hironaka K, Ozaki N, Hattori H, Nagamine K, Nakashima H, Ueda M, Sugiura Y.Involvement of glial activation in trigeminal ganglion in a rat model of lower gingival cancer pain.Nagoya J Med Sci. 76(3-4):323-32, 2014
(2015年〜)
Kawai T, Katagiri W, Osugi M, Sugimura Y, Hibi H, Ueda M.Secretomes from bone marrow-derived mesenchymal stromal cells enhance periodontal tissue regeneration.Cytotherapy. 17(4): 369-81, 2015
Ogata K, Katagiri W, Osugi M, Kawai T, Sugimura Y, Hibi H, Nakamura S, Ueda M.Evaluation of the therapeutic effects of conditioned media from mesenchymal stem cells in a rat bisphosphonate-related osteonecrosis of the jaw-like model.Bone. 74: 95-105, 2015
Matsubara K, Matsushita Y, Sakai K, Kano F, Kondo M, Noda M, Hashimoto N, Imagama S, Ishiguro N, Suzumura A, Ueda M, Furukawa K, Yamamoto A.Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering macrophage polarity.J Neurosci. 35(6):2452-64, 2015
Fujii H, Matsubara K, Sakai K, Ito M, Ohno K, Ueda M, Yamamoto A.Dopaminergic differentiation of stem cells from human deciduous teeth and their therapeutic benefits for Parkinsonian rats.Brain Res. 1613:59-72, 2015
Wakayama H, Hashimoto N, Matsushita Y, Matsubara K, Yamamoto N, Hasegawa Y, Ueda M, Yamamoto A.Factors secreted from dental pulp stem cells show multifaceted benefits for treating acute lung injury in mice.Cytotherapy. 17(8):1119-29, 2015
Ichimura N, Shinjo K, An B, Shimizu Y, Yamao K, Ohka F, Katsushima K, Hatanaka A, Tojo M, Yamamoto E, Suzuki H, Ueda M, Kondo Y.Aberrant TET1 Methylation Closely Associated with CpG Island Methylator Phenotype in Colorectal Cancer.Cancer Prev Res (Phila). 8(8):702-11, 2015
Omori M, Tsuchiya S, Hara K, Kuroda K, Hibi H, Okido M, Ueda M.A new application of cell-free bone regeneration: immobilizing stem cells from human exfoliated deciduous teeth-conditioned medium onto titanium implants using atmospheric pressure plasma treatment.Stem Cell Res Ther. 6:124, 2015
Mita T, Furukawa-Hibi Y, Takeuchi H, Hattori H, Yamada K, Hibi H, Ueda M, Yamamoto A.Conditioned medium from the stem cells of human dental pulp improves cognitive function in a mouse model of Alzheimer's disease.Behav Brain Res. 293:189-97, 2015
Tsuchiya S, Ohmori M, Hara K, Fujio M, Ikeno M, Hibi H, Ueda M.An Experimental Study on Guided Bone Regeneration Using a Polylactide-co-glycolide Membrane-Immobilized Conditioned Medium.Int J Oral Maxillofac Implants. 30(5):1175-86, 2015
Izumoto-Akita T, Tsunekawa S, Yamamoto A, Uenishi E, Ishikawa K, Ogata H, Iida A, Ikeniwa M, Hosokawa K, Niwa Y, Maekawa R, Yamauchi Y, Seino Y, Hamada Y, Hibi H, Arima H, Ueda M, Oiso Y.Secreted factors from dental pulp stem cells improve glucose intolerance in streptozotocin-induced diabetic mice by increasing pancreatic β-cell function.BMJ Open Diabetes Res Care. 3(1):e000128, 2015
Hattori Y, Kim H, Tsuboi N, Yamamoto A, Akiyama S, Shi Y, Katsuno T, Kosugi T, Ueda M, Matsuo S, Maruyama S.Therapeutic Potential of Stem Cells from Human Exfoliated Deciduous Teeth in Models of Acute Kidney Injury.PLoS One. 10(10):e0140121, 2015
Yamaguchi S, Shibata R, Yamamoto N, Nishikawa M, Hibi H, Tanigawa T, Ueda M, Murohara T, Yamamoto A.Dental pulp-derived stem cell conditioned medium reduces cardiac injury following ischemia-reperfusion.Sci Rep. 5:16295, 2015
Hattori Y, Kim H, Tsuboi N, Yamamoto A, Akiyama S, Shi Y, Katsuno T, Kosugi T, Ueda M, Matsuo S, Maruyama S.Correction: Therapeutic Potential of Stem Cells from Human Exfoliated Deciduous Teeth in Models of Acute Kidney Injury.PLoS One. 10(11):e0143561, 2015
(2016年〜)
Ishikawa J, Takahashi N, Matsumoto T, Yoshioka Y, Yamamoto N, Nishikawa M, Hibi H, Ishigro N, Ueda M, Furukawa K, Yamamoto A.Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental rheumatoid arthritis.Bone. 83:210-219, 2016
Shimojima C, Takeuchi H, Jin S, Parajuli B, Hattori H, Suzumura A, Hibi H, Ueda M, Yamamoto A.Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis.J Immunol. 196(10):4164-71, 2016
Hirata M, Ishigami M, Matsushita Y, Ito T, Hattori H, Hibi H, Goto H, Ueda M, Yamamoto A.Multifaceted Therapeutic Benefits of Factors Derived From Dental Pulp Stem Cells for Mouse Liver Fibrosis.Stem Cells Transl Med.5(10):1416-1424, 2016
Hishida S, Ozaki N, Honda T, Shigetomi T, Ueda M, Hibi H, Sugiura Y.Atrophy of submandibular gland by the duct ligation and a blockade of SP receptor in rats.Nagoya J Med Sci.78(2):215-27, 2016
(2017年〜)
Fujio M, Xing Z, Sharabi N, Xue Y, Yamamoto A, Hibi H, Ueda M, Fristad I, Mustafa K.Conditioned media from hypoxic-cultured human dental pulp cells promotes bone healing during distraction osteogenesis.J Tissue Eng Regen Med. 11(7):2116-2126, 2017
Al-Sharabi N, Mustafa M, Ueda M, Xue Y, Mustafa K, Fristad I.Conditioned medium from human bone marrow stromal cells attenuates initial inflammatory reactions in dental pulp tissue.Dent Traumatol. 33(1):19-26, 2017
Kano F, Matsubara K, Ueda M, Hibi H, Yamamoto A.Secreted Ectodomain of Sialic Acid-Binding Ig-Like Lectin-9 and Monocyte Chemoattractant Protein-1 Synergistically Regenerate Transected Rat Peripheral Nerves by Altering Macrophage Polarity.Stem Cells. 35(3):641-653, 2017
Ito T, Ishigami M, Matsushita Y, Hirata M, Matsubara K, Ishikawa T, Hibi H, Ueda M, Hirooka Y, Goto H, Yamamoto A.Secreted Ectodomain of SIGLEC-9 and MCP-1 Synergistically Improve Acute Liver Failure in Rats by Altering Macrophage Polarity.Sci Rep. 7:44043, 2017
Itaya T, Hirai T, Hirai T, Numoto H, Takeda H, Ueda M.The Use of Fibroblasts for Ameliorating Structural Changes Associated with Skin Aging.Rejuvenation Res. 20(5):383-388, 2017
(2022年〜)
Neurology and Neurorehabilitation 2022, Vol. 4, Issue 2, 011-015 The First in Human Case of Amyotrophic Lateral Sclerosis Treated with Stem Cell-Derived Conditioned Medium: A 1-Year- Follow Up Minoru Ueda1,2* and Yasuhiro Seta3  1Department of Medicine, Postgraduate School of Medicine, Emeritus of Nagoya University, Nagoya, Japan 2President of SAISEIKEN Co. LTD, Tokyo, Japan  3Director of Smart Clinic Tokyo, Tokyo, Japan
Special Lecture in the Annual Meeting in Göteborg University (1990.5.22 Göteborg, Sweden) Ueda M, Kaneda T Bioartificial mucosa for maxillofacial surgery.
Special Lecture in Honor of Opening Ceremony of Newly Constructed Hospital of the Korea University (1991.6.22 Seoul, Korea) Ueda M Osseointegrated implant for maxillofacial reconstructive surgery.
1st international Symposium of Wound healing (1993.6.22) Ueda M In vitro analysys of wound healing using mucosal tissue model.
Kaunas Medical Academy (1993.6.21-25 Kaunas, Lithuania) Ueda M Recent advance of maxillofacial surgery in Japan.
International Symposium on Wound Healing and Tissue Regeneration (1995.2.22-24 Hiroshima, Japan) Ueda M, Hata K, Takahashi K. Cell kinetic analysis of wound contraction using connective tissue model and computer simulation.
Academy of Osseointegration 10th Annual Meeting (1995.3.2-4 Chicago, U.S.A.) Ueda M, Ohkubo H, Yamamoto H, Sawaki Y. Mandibular lengthening by intraoral distraction using osseointegrated implants.
Brånemark System 30 Year Anniversary (1995.8.17-19 Gothenburg, Sweden) Ueda M, Ohkubo H, Hibi H, Sawaki Y. Mandibular lengthening by distraction osteogenesis using osseointegrated implants and an intraoral device Ueda M, Hata K, Murakami I, Niimi A. Vestibloplasty for implant therapy using cultured mucosal epithelium.
Academy of Osseointegration 11th Annual Meeting (1996.2.29-3.2 New York, U.S.A.) Ueda M, Sawai Y, Ohkubo H, Yamamoto H. Osteomorphous control of craniofacial skelton by distraction osteogenesis using osseointegrated implants.
12th Annual Meeting Academy of Osseointegration (1997.3.6-8 San Francisco, U.S.A.) Ueda M, Hata K, Niimi A.Peri-implant soft tissue management using cultured mucosal epithelium.
International Congress on Cranial and Facial Bone Distraction Processes (1997.6.20-21 Paris, France) Ueda M. Maxillofacial bone distraction processes using osseointegrated implant and intraoral device.
13th European Conference on Biomaterials (1997.9.4-7 Gothenburg, Sweden) Ueda M. Establishment of bio-skin bank using human living cells.
13th International Conference on Oral and Maxillofacial Surgery (1997.10.20-24 Tokyo, Japan)Ueda M. Osteomorphous control by distraction osteogenesis using osseointegrated implant in maxillofacial region.
13th Annual Meeting of Academy of Osseointegration (1998.3.5-7 Atlanta, U.S.A.) Ueda M, Sawaki Y, Oda T. Ridge augmentation by distraction osteogenesis using osseointegrated implants.
Association for Dental Science of the Republic of China (1998.4.10-12 Taiwan)Ueda M. The effect of teeth loss on spatial memory and acetylcholine release from the parietal cortex in aged rats.
The 3rd Japan-China Conference on Oral Biology and Science (1998.8.10-13 China) Ueda M. Bioartificial skin using cultured living cells - the present and the future.
The 6th Japan-Russia Medical Exchange Foundation International Symposium (1998.8.24-25 Khabarovsk, Russia) Ueda M.Clinical results of cultured epithelial grafting.
1st Craniofacial Distraction Osteogenesis (1998.11.18-22 Malaysia) Ueda M. Osteomorphous control by distraction osteogenesis using osseointegrated implants Ueda M.A pilot of motor driven distraction device for mandibular reconstruction.
2nd Bi-annual Meeting of the Tissue Engineering Society(1998.12.4-6 Orland, Florida, U.S.A.) Ueda M. Establishment of bio-skin bank and its clinical results in japan.
The20th Annual conference of the America College of Oral and Maxillofacial Surgery (1999.2.25-28 Orland, U.S.A.) Ueda M. Biology of distruction osteogenesis using osseointegrated implant.
Global Aspects on Function and Esthetics by Design (1999.3.3 Palm Springs, U.S.A.)Ueda M. A new horizon in implant dentistry using tissue engineered matererials .
2nd International Congress on Cranial and Facial Bone Distraction Processes (1999.6.17-19 Paris, France) Ueda M.Biological basis of distraction osteogenesis.
Lecture in Tübingen Univeresity (1999.6.21-25 Germany) Ueda M. Ossification Mechanism in Distraction Osteogenesis-In Vivo and In Vitro Study.
第38回顎顔面形成再建外科学会 (1999.11.4-6 Korea) Ueda M. Biology of distraction osteogenesis with use of osseointegrated implants -in vivo and in vitro study-
Asian Dentech2000 (2000.1.27-30 Hong Kong) Ueda M. Tissue engineering, application for implant surgery.
Pittsburgh Orthopaedic Tissue Engineering Symposium Ueda M.Applications in oral surgery.
International Tissue Engineering Meeting (2000.5.18-20 Austria)Ueda M. Tissue engineering: application in oral surgery.
Kyung pook National University (2000.12.15-16 Korea) Ueda M.Soft & hard tissue engineering: application in dental implant surgery.
Basic and Clinical Research in Skeletal Tissue Engineering; Perspectives (2001.5.9-12 Italy) Ueda M. Basic and clinical research in maxillofacial bone surgery.
The 3rd International Symposium on Tissue Engirneering (2001.6.1 Seoul, Korea) Ueda M. Tissue engineering in oral surgery and recent advances in Japanese Tissue Engineering Society.
3rd International Congress of Craniofacial and Maxillofacial Distraction (2001.6.14-16 France) Ueda M. Research on bone distraction.
Second International Symposium on Biomimetic Materials Processing (2002.1.15-17 Nagoya, Japan) Ueda M. Strategy for maxillofacial bone regeneration using tissue engineering concept.
29th Annual Meeting and Exposition of the Controlled Release Society (2002.7.22-25 Seoul, Korea) Ueda M. Strategy for maxillofacial bone reconstraction using tissue engineering concept.