tbuckley/cabot-search huggingface dataset:
Effectiveness of exercise-based sports injury prevention programmes in reducing injury rates in adolescents and their implementation in the community: a mixed-methods systematic review
Authors: Zhe Xin Zhang, Joseph Lai, Liang Shen, Lingaraj Krishna
Journal: British Journal of Sports Medicine (2024)

Objective Despite evidence supporting the efficacy of sport injury prevention programmes (SIPPs) in adolescents, implementation of SIPPs in community settings is low. This review aims to synthesise and integrate evidence on the efficacy of exercise-based SIPPs in reducing injury rates in adolescents with implementation strategies for such programmes in the community. Design A systematic review with meta-analysis, narrative synthesis and meta-aggregation was conducted, followed by a convergent segregated approach to integrate the findings. Sensitivity and subgroup analyses were conducted. Study appraisal was performed using Joanna Briggs Institute Critical Appraisal Checklists and Mixed Methods Appraisal Tool. Data sources Literature search of nine databases was carried out to identify studies in English from January 2012 to December 2022. Eligibility criteria Included were randomised controlled trials (RCTs), qualitative or mixed-methods studies. Population included adolescents (10–19 years). Interventions included SIPPs. Outcomes were injury rate and rate ratio (IRR). Phenomena of interest were facilitators and barriers to the implementation of SIPPs. Results 23 studies were included for analysis. Meta-analysis for 16 RCTs showed a protective effect of SIPP (IRR 0.63, 95% CI 0.53 to 0.74, p&lt;0.00001) in adolescents. Meta-aggregation of seven qualitative/mixed-method studies revealed four sets of synthesised findings that impact implementation namely players’ perceptions and beliefs, coaches as key facilitators, organisational support and characteristics of the SIPP. Conclusion Implementation of SIPPs provides a 37% risk reduction in adolescents but requires targeting key stakeholders through a top-down multifaceted approach for its efficacy to be translated. Future research should investigate the effectiveness of SIPPs and implementation strategies in adolescents in community settings.
Chimeric antigen receptor T-cell infusion for large B-cell lymphoma in complete remission: a center for international blood and marrow transplant research analysis
Authors: Trent P Wang, Kwang W Ahn, Mazyar Shadman, Manmeet Kaur, Nausheen Ahmed, Ulrike Bacher, Jan Cerny, Andy Chen, Narendranath Epperla, Matthew Frigault, Natalie Grover, Bradley Haverkos, Brian Hill, Nasheed Hossain, Madiha Iqbal, Tania Jain, Maxwell M Krem, Joseph Maakaron, Dipenkumar Modi, Muhamad Alhaj Moustafa, Peter Riedell, Bipin Savani, R Alejandro Sica, Anna Sureda, Kitsada Wudhikarn, Alex F Herrera, Craig Sauter, Mehdi Hamadani, Antonio Jimenez Jimenez
Journal: Leukemia (2024)
OCT-Guided vs Angiography-Guided Coronary Stent Implantation in Complex Lesions
Authors: Ziad A Ali, Ulf Landmesser, Akiko Maehara, Doosup Shin, Koshiro Sakai, Mitsuaki Matsumura, Richard A Shlofmitz, David Leistner, Paolo Canova, Fernando Alfonso, Franco Fabbiocchi, Giulio Guagliumi, Matthew J Price, Jonathan M Hill, Takashi Akasaka, Francesco Prati, Hiram G Bezerra, William Wijns, Robert J McGreevy, Robert W McNutt, Hong Nie, Kanitha Phalakornkule, Jana Buccola, Gregg W Stone
Journal: Journal of the American College of Cardiology (2024)
Three‐dimensional telomere profiling predicts risk of progression in smoldering multiple myeloma
Authors: Shaji Kumar, S. Vincent Rajkumar, Dragan Jevremovic, Robert A. Kyle, Yulia Shifrin, Michelle Nguyen, Zahabiya Husain, Asieh Alikhah, Anita Jafari, Sabine Mai, Kenneth Anderson, Sherif Louis
Journal: American Journal of Hematology (2024)

Abstract Smoldering multiple myeloma (SMM) is a precursor stage that precedes multiple myeloma (MM). SMM is heterogenous with nearly 40% of patients progressing to MM in the first 5 years. The high rate of progression of SMM patients highlights the need for early intervention, which underscores the importance of identifying SMM patients with the highest risk of progression. Several risk stratification models showed utility in identifying high‐risk SMM patients; however, these systems showed limited sensitivity. To date, identifying high‐risk SMM patients remains an important clinical need. In this study, we present the 3‐dimensional telomere profiling as a structural biomarker capable of stratifying SMM patients as a function of genomic instability. Quantifying telomere dysfunction using the TeloView technology showed utility in risk stratification of cancer patients, particularly hematological malignancies. In this study, we analyzed 168 SMM patients. We report an AUC in ROC analysis of 0.8 using a subset of the patients as a training dataset. We then conducted a blind validation on a different cohort and demonstrated a positive predictive value of 85% and negative predictive value of 73%, with sensitivity and specificity of 83% and 76%, respectively. We examined the correlation between the TeloView prediction and the 20‐2‐20 scoring system, and cytogenetic abnormalities. We report a correlation of 53% with the 20‐2‐20 scores and over 60% correlation with cytogenetic abnormalities. The result of this study presents the telomere profiling as an effective biomarker able to stratify SMM patients to their respective risk groups with high sensitivity and specificity.
Genotoxicity associated with retroviral CAR transduction of ATM-deficient T cells
Authors: Meir Rozenbaum, Reut Fluss, Victoria Marcu-Malina, Ifat Sarouk, Amilia Meir, Sarah Elitzur, Tal Zinger, Jasmine Jacob-Hirsch, Efrat G. Saar, Gideon Rechavi, Elad Jacoby
Journal: Blood Cancer Discovery (2024)

Somatic variants in DNA damage response genes such as ATM are widespread in hematologic malignancies. ATM protein is essential for double-strand DNA break repair. Germline ATM deficiencies underlie ataxia-telangiectasia (A-T), a disease manifested by radiosensitivity, immunodeficiency, and predisposition to lymphoid malignancies. Patients with A-T diagnosed with malignancies have poor tolerance to chemotherapy or radiation. In this study, we investigated chimeric antigen receptor (CAR) T cells using primary T cells from patients with A-T (ATM-/-), heterozygote donors (ATM+/-), and healthy donors. ATM-/- T cells proliferate and can be successfully transduced with CARs, though functional impairment of ATM-/- CAR T-cells was observed. Retroviral transduction of the CAR in ATM-/- T cells resulted in high rates of chromosomal lesions at CAR insertion sites, as confirmed by next-generation long-read sequencing. This work suggests that ATM is essential to preserve genome integrity of CAR T-cells during retroviral manufacturing, and its lack poses a risk of chromosomal translocations and potential leukemogenicity. Significance: CAR T-cells are clinically approved genetically modified cells, but the control of genome integrity remains largely uncharacterized. This study demonstrates that ATM deficiency marginally impairs CAR T-cell function and results in high rates of chromosomal aberrations after retroviral transduction, which may be of concern in patients with DNA repair deficiencies.
Long-term Remissions Following CD20-directed Chimeric Antigen Receptor Adoptive T cell Therapy
Authors: George Mo, Sang Y. Lee, David G. Coffey, Valentin Voillet, Ilan R. Kirsch, Raphael Gottardo, Kimberly S. Smythe, Cecilia C.S. Yeung, Adam Greenbaum, Damian J. Green, David G. Maloney, Brian G. Till
Journal: Blood Cancer Discovery (2024)

Chimeric antigen receptor (CAR) T-cell therapy produces high response rates in refractory B-cell non-Hodgkin lymphoma, but long-term data are minimal to date. In this study, we present long-term follow-up of a pilot trial testing a CD20-targeting third-generation CAR in patients with relapsed B-cell lymphomas following cyclophosphamide-only lymphodepletion. Two of the three patients in the trial, with mantle cell lymphoma and follicular lymphoma, had remissions lasting more than 7 years, though they ultimately relapsed. The absence of B-cell aplasia in both patients suggested a lack of functional CAR T-cell persistence, leading to the hypothesis that endogenous immune responses were responsible for these long-term remissions. Correlative immunologic analyses supported this hypothesis, with evidence of new humoral and cellular antitumor immune responses proximal to clinical response time points. Collectively, our results suggest that CAR T-cell therapy may facilitate epitope spreading and endogenous immune response formation in lymphomas. Significance: Two of three patients treated with CD20-targeted CAR T-cell therapy had long-term remissions, with evidence of endogenous antitumor immune response formation. Further investigation is warranted to develop conditions that promote epitope spreading in lymphomas.
Individualized Risk of CKD Progression among US Adults
Authors: Maria Clarissa Tio, Javed Butler, Xiaoqian Zhu, Yoshitsugu Obi, Timothy E. Yen, Kamyar Kalantar-Zadeh, Elani Streja, Neville R. Dossabhoy, Michael E. Hall, Tariq Shafi
Journal: Journal of the American Society of Nephrology (2024)

Key Points A total of 8.42 million US adults have high CKD progression risk, and 4.77 million of them have eGFR &gt;60 ml/min per 1.73 m 2 . An individual's absolute risk of CKD progression is important in the diagnosis and prognostication of CKD. Background CKD is currently defined using GFR or albuminuria. This is on the basis of the relative risk of mortality and kidney outcomes compared with a healthy population and does not consider an individual's absolute risk of CKD progression. Methods Using National Health and Nutrition Examination Survey data from 1999 to 2020, we characterized the individual-level absolute 3-year risk of ≥40% decline in eGFR (ml/min per 1.73 m 2 ) or kidney failure (3-year risk) among US adults. We categorized the 3-year risk and considered ≥5% as high risk. Results Among 199.81 million US adults, 8.42 million (4%) had a 3-year risk ≥5%, including 1.04 million adults without CKD (eGFR ≥60 and albuminuria &lt;30 mg/g). These high-risk adults without CKD as currently defined had risk factors including hypertension (98%), heart failure (72%), and diabetes (44%). A total of 15.51 million adults had CKD with preserved eGFR (eGFR ≥60 and albuminuria ≥30 mg/g)—3.73 million had a 3-year risk ≥5%, 41% of whom did not have diabetes and thus would not be screened for albuminuria using current screening recommendations. The 3-year risk of CKD progression was low (risk &lt;5%) in 94% of the 5.66 million US adults with CKD stage G3a-A1 (eGFR 45 to &lt;60 and albuminuria &lt;30 mg/g). Conclusions Assessment of the individual's absolute risk of CKD progression allowed further risk stratification of patients with CKD and identified individuals without CKD, as currently defined, who were at high risk of CKD progression. Podcast This article contains a podcast at https://dts.podtrac.com/redirect.mp3/www.asn-online.org/media/podcast/JASN/2024_06_18_ASN0000000000000377.mp3
Nationally Automated Colonoscopy Performance Feedback Increases Polyp Detection: The NED APRIQOT Randomized Controlled Trial
Authors: Jamie Catlow, Linda Sharp, Janelle Wagnild, Liya Lu, Rashmi Bhardwaj-Gosling, Emmanuel Ogundimu, Adetayo Kasim, Matthew Brookes, Thomas Lee, Stephen McCarthy, Joanne Gray, Falko Sniehotta, Roland Valori, Claire Westwood, Richard McNally, Josephine Ruwende, Simon Sinclair, Jill Deane, Matt Rutter
Journal: Clinical Gastroenterology and Hepatology (2024)

BACKGROUND & AIMS:Postcolonoscopy Q10 colorectal cancer incidence and mortality rates are higher for endoscopists with low polyp detection rates.Using the UK's National Endoscopy Database (NED), which automatically captures real-time data, we assessed if providing feedback of case-mix-adjusted mean number of polyps (aMNP), as a key performance indicator, improved endoscopists' performance.Feedback was delivered via a theory-informed, evidence-based audit and feedback intervention. METHODS:This multicenter, prospective, NED Automated Performance Reports to Improve Quality Outcomes Trial randomized National Health Service endoscopy centers to intervention or control.Intervention-arm endoscopists were e-mailed tailored monthly reports automatically generated within NED, informed by qualitative interviews and behavior change theory.The primary outcome was endoscopists' aMNP during the 9-month intervention. RESULTS:From November 2020 to July 2021, 541 endoscopists across 36 centers (19 intervention; 17 control) performed 54,770 procedures during the intervention, and 15,960 procedures during the 3-month postintervention period.Comparing the intervention arm with the control arm, endoscopists during the intervention period: aMNP was nonsignificantly higher (7%; 95% CI, -1% to 14%; P [ .08).The unadjusted MNP (10%; 95% CI, 1%-20%) and polyp detection rate (10%; 95% CI, 4%-16%) were significantly higher.Differences were not maintained in the postintervention period.In the intervention arm, endoscopists accessing NED Automated Performance Reports to Improve Quality Outcomes Trial webpages had a higher aMNP than those who did not (aMNP, 118 vs 102; P [ .03). CONCLUSIONS:Although our automated feedback intervention did not increase aMNP significantly in the intervention period, MNP and polyp detection rate did improve significantly.Engaged endoscopists benefited most and improvements were not maintained postintervention; future work should address engagement in feedback and consider the effectiveness of continuous feedback.www.isrctn.
Plasmodium ovale spp dhfr mutations associated with reduced susceptibility to pyrimethamine in sub-Saharan Africa: a retrospective genetic epidemiology and functional study
Authors: Valentin Joste, Romain Coppée, Justine Bailly, Yann Rakotoarivony, Francine Ghislaine Toko Tchokoteu, Shany Achache, Bruno Pradines, Gilles Cottrell, Frédéric Ariey, Nimol Khim, Jean Popovici, Toshihiro Mita, Mirjam Groger, Michael Ramharter, Timothy Egbo, Dennis W Juma, Hoseah Akala, Sandrine Houzé, Jérôme Clain, Ahmed Abou-Bacar, Patrice Agnamey, Nawel Ait-Ammar, Adela Angoulvant, Nicolas Argy, Daniel Azjenberg, Louise Basmaciyan, Patrick Bastien, Sorya Belaz, Ghania Belkadi, Anne-Pauline Bellanger, Dieudonné Bemba, Antoine Berry, François Botterel, Vincent Bouden, Marie-Elisabeth Bougnoux, Azza Bouzayene, Laurent Bret, Stéphane Bretagne, Caren Brumpt, Bernadette Buret, Pauline Caraux-Paz, Agnes Cheruiyot, Alexandre Chlilek, Sylvain Clauser, Sandrine Cojean, Bernadette Cuisenier, Naima Dahane, Eric Dannaoui, Céline Dard, Marie-Laure Dardé, Ludovic de Gentile, Anne Debourgogne, Célia Dechavanne, Pascal Delaunay, Anne Delaval, Anne-Sophie Deleplancque, Guillaume Desoubeaux, Nathalie Desuremain, Michel Develoux, Armel Djènontin, Yannelle Dossou, Rémy Durand, Marie-Fleur Durieux, Emmanuel Dutoit, Odile Eloy, Odile Fenneteau, Nadine Fievet, Gilles Gargala, Cécile Garnaud, Françoise Gay-Andrieu, Nadine Godineau, Alain Gravet, Nadia Guennouni, Jérôme Guinard, Samia Hamane, Antoine Huguenin, Jacqueline Jumah, Coralie L'Ollivier, Luce Landraud, Sébastien Larréché, Rose-Anne Lavergne, Yohann Le Govic, Caroline Lohmann, Marie-Claire Machouart, Anthony Marteau, Achille Massougbodji, Edith Mazars, Matthieu Mechain, Ana Mendes Moreira, Célia Merat, Laurence Millon, Ghyslain Mombo-Ngoma, Christelle Morelle, Florent Morio, Edwin Mwakio, René Nabias, Céline Nourrisson, Benjamin Opot, Raphael Okhot, Pierre Patoz, Pascal Penn, Estelle Perraud-Cateau, Marc Pihet, Jean-Etienne Pilo, Thierry Pistone, Isabelle Poilane, Christelle Pomares, Denis Pons, Laurence Pougnet, Lauren Pull, Dorothée Quinio, Didier Raffenot, Christophe Rapp, Marie-Catherine Receveur, Gabrielle Roosen, Véronique Sarrasin, Milene Sasso, Hélène Savini, Yaye Senghor, Muriel Silva, Fabrice Simon, Jean-Yves Siriez, Darius Sossou, Marc Thellier, Maxime Thouvenin, Dominique Toubas, Cécile Tournus, Pauline Touroult-Jupin, Luzia Veletzky, Bertin Vianou, Rizwana Zaffaroullah, Rella Zoleko-Manego
Journal: The Lancet Microbe (2024)
Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study
Authors: John Muscedere, Sean M Bagshaw, Michelle Kho, Sangeeta Mehta, Deborah J Cook, J Gordon Boyd, Stephanie Sibley, Han T Wang, Patrick M Archambault, Martin Albert, Oleksa G Rewa, Ian Ball, Patrick A Norman, Andrew G Day, Miranda Hunt, Osama Loubani, Tina Mele, Aimee J Sarti, Jason Shahin
Journal: Intensive Care Medicine (2024)

Frailty is common in critically ill patients but the timing and optimal method of frailty ascertainment, trajectory and relationship with care processes remain uncertain. We sought to elucidate the trajectory and care processes of frailty in critically ill patients as measured by the Clinical Frailty Scale (CFS) and Frailty Index (FI).
Colorectal cancer-specific IFNβ delivery overcomes dysfunctional dsRNA-mediated type I interferon signaling to increase the abscopal effect of radiotherapy
Authors: Kevin Chih-Yang Huang, Shu-Fen Chiang, Hsin-Yu Chang, Wei-Ze Hong, Jhen-Yu Chen, Pei-Chih Lee, Ji-An Liang, Tao-Wei Ke, Shin-Lei Peng, An‑Cheng Shiau, Tsung-Wei Chen, Pei-Chen Yang, William Tzu-Liang Chen, K S Clifford Chao
Journal: Journal for ImmunoTherapy of Cancer (2024)

Background Cancer-intrinsic type I interferon (IFN-I) production triggered by radiotherapy (RT) is mainly dependent on cytosolic double-stranded DNA (dsDNA)-mediated cGAS/STING signaling and increases cancer immunogenicity and enhances the antitumor immune response to increase therapeutic efficacy. However, cGAS/STING deficiency in colorectal cancer (CRC) may suppress the RT-induced antitumor immunity. Therefore, we aimed to evaluate the importance of the dsRNA-mediated antitumor immune response induced by RT in patients with CRC. Methods Cytosolic dsRNA level and its sensors were evaluated via cell-based assays (co-culture assay, confocal microscopy, pharmacological inhibition and immunofluorescent staining) and in vivo experiments. Biopsies and surgical tissues from patients with CRC who received preoperative chemoradiotherapy (neoCRT) were collected for multiplex cytokine assays, immunohistochemical analysis and SNP genotyping. We also generated a cancer-specific adenovirus-associated virus (AAV)-IFNβ1 construct to evaluate its therapeutic efficacy in combination with RT, and the immune profiles were analyzed by flow cytometry and RNA-seq. Results Our studies revealed that RT stimulates the autonomous release of dsRNA from cancer cells to activate TLR3-mediated IFN-I signatures to facilitate antitumor immune responses. Patients harboring a dysfunctional TLR3 variant had reduced serum levels of IFN-I-related cytokines and intratumoral CD8 + immune cells and shorter disease-free survival following neoCRT treatment. The engineered cancer-targeted construct AAV-IFNβ1 significantly improved the response to RT, leading to systematic eradication of distant tumors and prolonged survival in defective TLR3 preclinical models. Conclusion Our results support that increasing cancer-intrinsic IFNβ1 expression is an immunotherapeutic strategy that enhances the RT-induced antitumor immune response in locally patients with advanced CRC with dysfunctional TLR3.
Senaparib as first-line maintenance therapy in advanced ovarian cancer: a randomized phase 3 trial
Authors: Xiaohua Wu, Jihong Liu, Jing Wang, Li Wang, Zhongqiu Lin, Xiaobin Wang, Jianqing Zhu, Beihua Kong, Junwei Fei, Ying Tang, Bairong Xia, Zhiqing Liang, Ke Wang, Yi Huang, Hong Zheng, An Lin, Kui Jiang, Wei Wang, Xin Wang, Ge Lou, Hongming Pan, Shuzhong Yao, Guiling Li, Min Hao, Yunlang Cai, Xuejun Chen, Zhijun Yang, Youguo Chen, Hongwu Wen, Pengpeng Qu, Cong Xu, Chih-Yi Hsieh, Manhua Cui, Lipai Chen, Ying Cheng, Weidong Zhao, Mei Pan, Yaling Tang, Yu Zhang, Xiaoyan Lin, Guzhalinuer Abulizi, Wei Duan, Linjuan Zeng
Journal: Nature Medicine (2024)
The killifish germline regulates longevity and somatic repair in a sex-specific manner
Authors: Eitan Moses, Tehila Atlan, Xue Sun, Roman Franěk, Atif Siddiqui, Georgi K Marinov, Sagiv Shifman, David M Zucker, Adi Oron-Gottesman, William J Greenleaf, Ehud Cohen, Oren Ram, Itamar Harel
Journal: Nature Aging (2024)
An in-depth evaluation of federated learning on biomedical natural language processing for information extraction
Authors: Le Peng, Gaoxiang Luo, Sicheng Zhou, Jiandong Chen, Ziyue Xu, Ju Sun, Rui Zhang
Journal: npj Digital Medicine (2024)

Abstract Language models (LMs) such as BERT and GPT have revolutionized natural language processing (NLP). However, the medical field faces challenges in training LMs due to limited data access and privacy constraints imposed by regulations like the Health Insurance Portability and Accountability Act (HIPPA) and the General Data Protection Regulation (GDPR). Federated learning (FL) offers a decentralized solution that enables collaborative learning while ensuring data privacy. In this study, we evaluated FL on 2 biomedical NLP tasks encompassing 8 corpora using 6 LMs. Our results show that: (1) FL models consistently outperformed models trained on individual clients’ data and sometimes performed comparably with models trained with polled data; (2) with the fixed number of total data, FL models training with more clients produced inferior performance but pre-trained transformer-based models exhibited great resilience. (3) FL models significantly outperformed pre-trained LLMs with few-shot prompting.
Immunotherapy and biologics in the management of <scp>IgE</scp>‐mediated food allergy: Systematic review and meta‐analyses of efficacy and safety
Authors: Carmen Riggioni, Teresa Oton, Loreto Carmona, George Du Toit, Isabel Skypala, Alexandra F. Santos
Journal: Allergy (2024)

Food allergy (FA) is a potentially life-threatening chronic condition that is becoming an increasing public health problem worldwide. This systematic review (SR) was carried out to inform the development of clinical recommendations on the treatment of IgE-mediated FA with biologics and/or IT for the update of the EAACI guidelines. A SR of randomized-controlled trials or quasi-controlled trials was carried out. Studies were identified via comprehensive search strategies in Medline, Embase, and Cochrane Library, up to April 2022.
Identification of a clinically efficacious CAR T cell subset in diffuse large B cell lymphoma by dynamic multidimensional single-cell profiling
Authors: Ali Rezvan, Gabrielle Romain, Mohsen Fathi, Darren Heeke, Melisa Martinez-Paniagua, Xingyue An, Irfan N. Bandey, Melisa J. Montalvo, Jay R. T. Adolacion, Arash Saeedi, Fatemeh Sadeghi, Kristen Fousek, Nahum Puebla-Osorio, Laurence J. N. Cooper, Chantale Bernatchez, Harjeet Singh, Nabil Ahmed, Mike Mattie, Adrian Bot, Sattva Neelapu, Navin Varadarajan
Journal: Nature Cancer (2024)
Science–policy research collaborations need philosophers
Authors: Mike D Schneider, Temitope O Sogbanmu, Hannah Rubin, Alejandro Bortolus, Emelda E Chukwu, Remco Heesen, Chad L Hewitt, Ricardo Kaufer, Hanna Metzen, Veli Mitova, Anne Schwenkenbecher, Evangelina Schwindt, Helena Slanickova, Katie Woolaston, Li-An Yu
Journal: Nature Human Behaviour (2024)
Decompressive craniectomy plus best medical treatment versus best medical treatment alone for spontaneous severe deep supratentorial intracerebral haemorrhage: a randomised controlled clinical trial
Authors: Jürgen Beck, Christian Fung, Daniel Strbian, Lukas Bütikofer, Werner J Z'Graggen, Matthias F Lang, Seraina Beyeler, Jan Gralla, Florian Ringel, Karl Schaller, Nikolaus Plesnila, Marcel Arnold, Werner Hacke, Peter Jüni, Alexander David Mendelow, Christian Stapf, Rustam Al-Shahi Salman, Jenny Bressan, Stefanie Lerch, Arsany Hakim, Nicolas Martinez-Majander, Anna Piippo-Karjalainen, Peter Vajkoczy, Stefan Wolf, Gerrit A Schubert, Anke Höllig, Michael Veldeman, Roland Roelz, Andreas Gruber, Philip Rauch, Dorothee Mielke, Veit Rohde, Thomas Kerz, Eberhard Uhl, Enea Thanasi, Hagen B Huttner, Bernd Kallmünzer, L Jaap Kappelle, Wolfgang Deinsberger, Christian Roth, Robin Lemmens, Jan Leppert, Jose L Sanmillan, Jonathan M Coutinho, Katharina A M Hackenberg, Gernot Reimann, Mikael Mazighi, Claudio L A Bassetti, Heinrich P Mattle, Andreas Raabe, Urs Fischer
Journal: The Lancet (2024)