MEDICINE'S GENETIC HORIZONS
Authors: J V NEEL
Journal: Annals of Internal Medicine (1958)

Editorial1 August 1958MEDICINE'S GENETIC HORIZONSJAMES V. NEEL, M.D.JAMES V. NEEL, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-49-2-472 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFor something over 500,000 years there have existed on this earth species of man with a cranial capacity approaching that of modern man. For at least 99% of that time span the generation-to-generation rate of cultural change has been, viewed from our current vantage point, almost unbelievably slow. By cultural change I mean nothing more profound than changes in the circumstances of day-to-day living. It took something like 75,000 years for the rough Chellean hand-axe to be replaced by the more even, symmetric Acheulian hand-axe in Western Europe during the Pleistocene. Then, starting with the Agricultural Revolution, and accelerating with...1 NeelSchull JVWJ: The effect of exposure to the atomic bombs on pregnancy termination in Hiroshima and Nagasaki, National Academy of Science, National Research Council Publication No. 461: xvi and 241, 1956. Google Scholar2 Neel JV: The delayed effects of ionizing radiation, J. A. M. A. 166: 908, 1958. CrossrefMedlineGoogle Scholar3 Auerbach C: Chemical mutagenesis, Biol. Reviews 24: 355, 1949. CrossrefMedlineGoogle Scholar4 Boyland E: Mutagens, Pharmacol. Rev. 6: 345, 1954. MedlineGoogle Scholar5 Barthelmess A: Mutagene Arzneimittel, Arzneimitt.-Forsch. 6: 157, 1956. MedlineGoogle Scholar6 Westergaard M: Chemical mutagenesis in relation to the concept of the gene, Experientia 13: 224, 1957. CrossrefMedlineGoogle Scholar7 MacMahonKoller BEK: Ethnic differences in the incidence of leukemia, Blood 12: 1, 1957. CrossrefMedlineGoogle Scholar8 Lewis EB: Leukemia and ionizing radiation, Science 125: 965, 1957. CrossrefMedlineGoogle Scholar9 Court Brown WM: Gonad doses from diagnostic and therapeutic radiology, in Effect of radiation on human heredity, 1957, World Health Organization, Geneva, pp. 95-99. Google Scholar10 Wood WB: The underlying cause of unrest in university medicine, J. A. M. A. 164: 548, 1957. CrossrefMedlineGoogle Scholar11 Beckman H: An end to tranquilization! Marquette M. Rev. 22: 114, 1957. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Presented at the Symposium on Genetics of the Thirty-ninth Annual Session of The American College of Physicians, Atlantic City, New Jersey, April 30, 1958.From The Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEvolutionary Health PromotionJames V. Neel, M.D., Ph.D. (March 22, 1915–January 31, 2000): Founder EffectHereditary aspects of coronary heart diseaseEditorialDie sogenannten funktionellen Krankheiten des kardiovaskulären Systems als Syndrome der neurokardiovaskulären Inadaptation betrachtet 1 August 1958Volume 49, Issue 2Page: 472-476KeywordsGeneticsHuman genetics ePublished: 1 December 2008 Issue Published: 1 August 1958 PDF downloadLoading ...