tbuckley/cabot-search huggingface dataset:
DRUG-COATED BALLOON VERSUS DRUG-ELUTED STENTS FOR TREATMENT OF DE NOVO SEVERE CORONARY ARTERY DISEASE: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
Authors: Hassaan Arshad, Muhammad Haisum Maqsood, Safi Khan, Philip LaCombe, Joe Aoun, Alpesh R. Shah, Sachin S. Goel, Neal S. Kleiman
Journal: Journal of the American College of Cardiology (2025)
MECHANISM OF LEFT MAIN IN-STENT RESTENOSIS EVALUATED BY INTRAVASCULAR ULTRASOUND
Authors: JIAWEI WU, Takunori Tsukui, Takehiko Kido, Mitsuaki Matsumura, Khady N. Fall, Megha Prasad, Sanjum S. Sethi, Tamim Nazif, Sahil A. Parikh, Torsten Peter Vahl, Leroy E. Rabbani, Vivian G. Ng, Michael B. Collins, Martin B. Leon, Jeffrey W. Moses, Margaret McEntegart, Ajay J. Kirtane, Gary S. Mintz, Akiko Maehara
Journal: Journal of the American College of Cardiology (2025)
BEYOND THE TEXTBOOK: UNCONVENTIONAL PERCUTANEOUS MITRAL BALLOON VALVULOPLASTY (PMBV) AND ITS IMPLICATIONS FOR DEVELOPMENT: CHALLENGES, LESSONS AND INSIGHTS
Authors: Shakir Zada, Naveed Ullah Khan, Shueeta Kumari, Ejaz Ul Haq, Paras Kalwar, Elham Yousafzai, Poonam Bai, Ishrat Fatima, Naeem Mengal, Jehangir Ali Shah, ABDUL HAMEED, Syeda Kahkashan Zehra, Ibrar hussain, Akhlaq Muhammad, Khalid Bhatti, Rukhsar Memon, Muhammad Zeb, Abdul Hakeem, Saghir Tahir, Jawaid A. Sial
Journal: Journal of the American College of Cardiology (2025)
ADVERSE EVENTS AND MODES OF FAILURE RELATED TO AGENT DRUG COATED BALLOON: A FDA MANUFACTURER AND USER FACILITY DEVICE EXPERIENCE (MAUDE) STUDY
Authors: Pallavi Matai, Sulochana Khadka, Anas Atrash, Silvana Ribeiro Papp, Gabriela Michelle Calderon Barahona
Journal: Journal of the American College of Cardiology (2025)
DRUG-COATED BALLOONS FOR THE TREATMENT OF IN-STENT RESTENOSIS: AN UPDATED SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
Authors: Manojna Guntipalli, OGECHUKWU OBI, Teenu Maria Jeswin, Rushern Naidoo, Amine Ghenai, Nishi Kansara, Syed Karam Gardezi, Sandra Mani, Taqiyah Sheriff, Sinda Hidri, Muhammad Ehsan
Journal: Journal of the American College of Cardiology (2025)
PREDICTORS OF LUMINAL GAIN AFTER TREATING FIBROTIC IN-STENT RESTENOTIC LESIONS AS EVALUATED BY OPTICAL COHERENCE TOMOGRAPHY
Authors: Takehiko Kido, Takunori Tsukui, Mitsuaki Matsumura, Emma Caron, Matthew Cannata, Yasemin Ciftcikal, Doosup Shin, KOSHIRO SAKAI, Evan Shlofmitz, Jeffrey W. Moses, Omar K. Khalique, David J. Cohen, Gary S. Mintz, Richard A. Shlofmitz, Allen Jeremias, Ziad A. Ali, Akiko Maehara
Journal: Journal of the American College of Cardiology (2025)
UNIFIED ECG CRITERIA FOR DIAGNOSING ATRIAL AND VENTRICULAR DISEASES IN PEDIATRIC PATIENTS: THE CHILDHEART PROJECT
Authors: Jose Nunes De Alencar Neto, Jade Monteiro, Julia Furtado, Rafael Sacre, Christine Brasil Guerra, Wagner Knoblauch, Sandro Felicioni, Mariana De Marchi, Kleber Gomes Franchini
Journal: Journal of the American College of Cardiology (2025)
OUTCOMES FOLLOWING TRANSCATHETER AORTIC VALVE REPLACEMENT FOR PATIENTS WITH SMALL AND LARGE ANNULUS ACROSS DIFFERENT FLOW-GRADIENT PATTERNS
Authors: Besir Besir, Shivabalan Kathavarayan Ramu, Maryam Muhammad Ali Majeed-Saidan, Judah Rajendran, Tamari Lomaia, Serge C. Harb, James Yun, Rishi Puri, Grant W. Reed, Amar Krishnaswamy, Samir R. Kapadia
Journal: Journal of the American College of Cardiology (2025)
CLINICAL CHARACTERISTICS AND OUTCOMES OF HEPATOCELLULAR CARCINOMA AFTER THE FONTAN: A SINGLE CENTER COHORT
Authors: Isabella Farkas, Srinivas Denduluri, Jungwon Min, Sara L. Partington, Emily Ruckdeschel, Sumeet Vaikunth, Maarouf Hoteit, Yuli Y. Kim
Journal: Journal of the American College of Cardiology (2025)
THE ROLE OF FRAGMENTED QRS COMPLEX IN PREDICTING RIGHT VENTRICULAR FUNCTION IN PATIENTS WITH REPAIRED TETRALOGY OF FALLOT: A META ANALYSIS
Authors: Wasfi Alghwyeen, Omar Khalid Samir Abdelkader, Ahmed Lotfy, Hebah Altaweel, Abed Dhaydel, Ahmad Saeed, Nada Ahmad Awamleh, Osama Younis
Journal: Journal of the American College of Cardiology (2025)
CHARACTERIZATION OF VASCULAR FUNCTION AND PHYSICAL ACTIVITY IN MATERNAL HEART DISEASE DURING THE MID-TRIMESTER OF PREGNANCY
Authors: Nicholas Cheung, Juliana Lasso-Mendez, Lisa K. Hornberger, Shauna Littlefair, Lily Lin, Jonathan Windram, Margie Davenport
Journal: Journal of the American College of Cardiology (2025)
RIGHT AND LEFT VENTRICULAR REMODELING AFTER ATRIAL SEPTAL DEFECT CLOSURE
Authors: Amr Saleh, Lavanya Bellumkonda, Mary Jo R. Rizzo, Douglas W. Heller, Dominic Francese, Daniela Tirziu, Alexandra J. Lansky, Lissa Sugeng, Ruchika Karnik
Journal: Journal of the American College of Cardiology (2025)
TYPE AND FREQUENCY OF ARRHYTHMIAS STATUS POST HYBRID PROCEDURE AT 6 YEARS OF AGE
Authors: Garrett Muckleroy, Phillip Cheng, Isaac Kistler, Sara Conroy, Samantha Fichtner, Omar Khalid, Mark E. Galantowicz, Anna Kamp, Clifford L. Cua
Journal: Journal of the American College of Cardiology (2025)
INVASIVE THERAPY VS CONSERVATIVE THERAPY FOR THE MANAGEMENT OF NSTEMI OR UNSTABLE ANGINA IN OCTOGENARIANS: A META-ANALYSIS OF THE RANDOMIZED CONTROLLED TRIALS
Authors: Prakash Upreti, Mohammad Hamza, Azka Naeem, Syed Ishaq, Adnan Saydawi, Yousef Alsmairat, Yasemin Bahar, Farah Yasmin, Mowaffak Alraiyes, M. Chadi Alraies
Journal: Journal of the American College of Cardiology (2025)
GENDER DISPARITIES AMONG TRANSCATHETER EDGE-TO-EDGE OPERATORS IN THE UNITED STATES
Authors: Smitha Narayana Gowda, Emily Cendrowski, Teodora Donisan, Timothy Franklin Simpson, Joaquin E. Cigarroa, Trevor Simard, Mohamad Adnan Alkhouli, Mackram F. Eleid, Charanjit S. Rihal, Mayra E. Guerrero
Journal: Journal of the American College of Cardiology (2025)
DIFFERING PRACTICE PATTERNS AND OUTCOMES FOR CHRONIC LIMB-THREATENING ISCHEMIA REVASCULARIZATION BY US REGIONS
Authors: Joseph Kim, Lorenzo Arvanitis, Siling Li, Yang Song, Eleni Whatley, Rebecca Ward, Rebecca Torguson, Misti Malone, Megan Talej, Junyong Fang, Brian Pullin, Robert W. Yeh, Eric Alexander Secemsky
Journal: Journal of the American College of Cardiology (2025)
STEMI CARE IN LOW-AND-MIDDLE-INCOME COUNTRIES: ASSESSMENT OF METRICS AND PERFORMANCE INDICATORS IN A SINGLE-CENTER PROGRAM
Authors: Samuel Gabino Guzman, Carlos Garcia Lithgow, Roberly Marcelino Camilo, Francisco José Mañan De La Cruz, Marlon Miguel Espaillat, Ricardo Blanchery, Diogenes Cuevas, Cesar J. Herrera
Journal: Journal of the American College of Cardiology (2025)
EFFECT OF INTRAVENOUS NICORANDIL THERAPY ON MYOCARDIAL FUNCTION IN STEMI PATIENTS UNDERGOING PRIMARY PCI: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
Authors: Hritvik Jain, NANDAN PATEL, Siddhant Passey, Taimurzeb Durrani, JYOTI JAIN, Ishita Gupta, Mayank Jha, Faizan Ahmed, Muhammad Muneeb Arshad, Raheel Ahmed, Rozi Khan, Thomas Alexander
Journal: Journal of the American College of Cardiology (2025)
CONCOMITANT LEFT ATRIAL APPENDAGE OCCLUSION DURING TRANSCATHETER AORTIC VALVE REPLACEMENT: INSIGHTS FROM 2016-2021 THE NATIONAL INPATIENT SAMPLE DATABASE
Authors: Daniel Hanna, Dhiran Verghese, Juan Sierra David, Wael Dakkak, Brian Solomon, Travis Howard, Luis H. Paz Rios, Mazen Albaghdadi, Roberto J. Cubeddu
Journal: Journal of the American College of Cardiology (2025)
RURAL AND SOCIOECONOMICALLY DISADVANTAGED PATIENTS SUFFERED POORER STEMI OUTCOMES BUT WERE NOT DISPROPORTIONATELY NEGATIVELY IMPACTED BY THE COVID-19 PANDEMIC
Authors: Collin P. Goebel, Amy Shepard, Giorgio Gimelli, Kurt M. Jacobson, david lewis, Amish N. Raval
Journal: Journal of the American College of Cardiology (2025)
ENDOVASCULAR STRATEGIES FOR INFERO-POPLITEAL ARTERY DISEASE: A NETWORK METAANALYSIS
Authors: Prakash Upreti, Rohit Goru, Mohammad Hamza, Ankit Hanmandlu, Safia Shaikh, Sivaram Neppala, Junaid Mir, Yasemin Bahar, M. Chadi Alraies
Journal: Journal of the American College of Cardiology (2025)
RESEARCH SITE CHARACTERISTICS IMPACT ON MINORITY ENROLLMENT: INSIGHTS FROM A POOLED DRUG ELUTING STENT PIVOTAL TRIAL ANALYSIS
Authors: Wayne B. Batchelor, Ariel Ash-Shakoor, Andrew Farb, Amanda Gaylord, Alisa Kotz, Rebecca Torguson, Ayobami Adebowale, Mauro Moscucci, Hongying N. Jiang, Rebecca Ward, Lydia Glaw, Bram D. Zuckerman, Abdulla Damluji
Journal: Journal of the American College of Cardiology (2025)
PERIPROCEDURAL OUTCOMES OF LEFT ATRIAL APPENDAGE OCCLUSION IN LOW VERSUS HIGH CHA2DS2-VASC SCORE
Authors: Yusef Saeed, Rafey Feroze, Nawaf Abdulaziz Alhabdan, Alex Cove, Nour Tashtish, Luis Augusto Dallan, Steven Filby
Journal: Journal of the American College of Cardiology (2025)
UTILITY OF INTRAAORTIC BALLOON COUNTERPULSATION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION COMPLICATED BY CARDIOGENIC SHOCK
Authors: Akhil S. Kallur, Abhinav Saxena, Shivani Gupta, Jesse Frye, Chad Gier, Paola Pastena, Tekene Figueira, Jordan Price, Travis J. Bench, Tahmid Rahman, Noelle Nora Mann, Edlira Tam, Michael Tao
Journal: Journal of the American College of Cardiology (2025)
CLINICAL CHARACTERISTICS AND LONGITUDINAL OUTCOMES OF A SOUTHEAST ASIAN TRANSCATHETER AORTIC VALVULAR IMPLANTATION REGISTRY
Authors: Joy Ong, Valerie Ramiro, Nicholas Chew, Soh Yu Hang, None Rodney, Ting Wei Teo, Aloysius Leow, Audrey Anyi Zhang, Ting Ting Low, James Wei Luen Yip, Jimmy Hon, Edgar Tay, Ivandito Kuntjoro, Yinghao Lim
Journal: Journal of the American College of Cardiology (2025)
PREDICTING AMBULATORY BLOOD PRESSURE RESPONSE AFTER ULTRASOUND RENAL DENERVATION THROUGH MACHINE LEARNING
Authors: Karl-Patrik Kresoja, Felix Mahfoud, Michel Azizi, Ajay J. Kirtane, Gilwoo Choi, Liang Zhai, Jiayu Chen, Philipp Lurz
Journal: Journal of the American College of Cardiology (2025)
COMPARATIVE EFFECTIVENESS OF MECHANICAL THROMBECTOMY VERSUS CATHETERDIRECTED THROMBOLYSIS IN OLDER ADULTS WITH PULMONARY EMBOLISM: A TARGET TRIAL EMULATION
Authors: Toshiki Kuno, Atsuyuki Watanabe, Yoshihisa Miyamoto, Hiroki Ueyama, Hiroshi Gotanda, Yusuke Tsugawa, Sripal Bangalore
Journal: Journal of the American College of Cardiology (2025)
IMPACT OF NON-ST SEGMENT ELEVATION MYOCARDIAL INFARCTION ON OUTCOMES IN PATIENTS ADMITTED WITH DIABETIC KETOACIDOSIS AND TRENDS OBSERVED WITH PERCUTANEOUS CORONARY INTERVENTION DURING 2017-2020 IN THE UNITED STATES: A NATIONAL INPATIENT SAMPLE ANALYSIS
Authors: Nishant Patel, Vishnu Shenoy, Sukhjeet Kaur, Aditya Desai, Bhavin Amrutbhai Patel, Abbas H. Mallick, Anusha Kavarthapu, Dhairya Nanavaty, Simran Tanna, Sai Harika Pujari, Sohrab Singh, Keerthireddy Ramireddy, Daniel Gonzalez Abascal, Pradeep Kumar Devarakonda, Sabah Siddiqui, Cesar Esteban Ayala-Rodriguez, Sarath Reddy, Kevin Luke Tsai
Journal: Journal of the American College of Cardiology (2025)
HEART FAILURE IS ASSOCIATED WITH WORSE IN-HOSPITAL OUTCOMES IN PATIENTS UNDERGOING SURGICAL PULMONARY VALVE REPLACEMENT OR REPAIR: A NATIONWIDE STUDY
Authors: Mohammad Ali Sheffeh, Judy Sheffeh, Jacob Klein, Omar J. Baqal, Dua A. Malik, Ider Oujamaa, Mustafa Turkmani, M. Chadi Alraies
Journal: Journal of the American College of Cardiology (2025)
ASSOCIATION OF INDEXED AORTIC DIMENSIONS WITH THE PRESENCE AND EXTENT OF CORONARY ARTERY ECTASIA IN PATIENTS WITH ACUTE CORONARY SYNDROME
Authors: Martijn Van Oort, Federico Oliveri, Madelien Veronique Regeer, Johan Wouter Jukema, Frank Van Der Kley, Ibtihal Al Amri, Jose Manuel Montero Cabezas
Journal: Journal of the American College of Cardiology (2025)
COMPARATIVE BETWEEN OUTCOMES OF SELF-EXPANDING AND BALLOON-EXPANDABLE TRANSCATHETER AORTIC VALVES IN PATIENTS WITH LEFT VENTRICULAR SYSTOLIC DYSFUNCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Sofian Mohamed M Zreigh, Ahmad Al Othman, Rafeek Elmezayen, Qasim Ezeddin Shawesh, Sara Saleh, Hajer Farrara, Aisha Ali, Baraa Muthanna Ali, Mustafa S. Zubaidi, Omar Hamza, Ali Elnaggar, Muhammed Elhadi
Journal: Journal of the American College of Cardiology (2025)
COMPARISON OF FASTING AND NON-FASTING REGIMENS OUTCOMES BEFORE CATHETERIZATION LABORATORY PROCEDURES: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Kaveh Hosseini, Shayan Shojaei, Hanieh Radkhah, Asma Mousavi, Mehrdad Mahalleh, Soheil Rahmati, Parnian Soltani, Mashood Farooqi, Mohammad Moein Ashrafi, sepideh jame bozorgi, Ali Moradi, Mani Khorsand Askari, Khurram Nasir, Jaime Almandoz, Toshiki Kuno, Diaa A. Hakim
Journal: Journal of the American College of Cardiology (2025)
ENDOVASCULAR STRATEGIES FOR FEMOROPOPLITEAL ARTERY DISEASE: A NETWORK-META ANALYSIS
Authors: Prakash Upreti, Rohit Goru, Mohammad Hamza, Ankit Hanmandlu, Safia Shaikh, Sivaram Neppala, Junaid Mir, Yasemin Bahar, M. Chadi Alraies
Journal: Journal of the American College of Cardiology (2025)
IMPACT OF AORTIC VALVE CALCIUM SCORE ON IN-HOSPITAL AND 1-YEAR OUTCOMES OF TAVR
Authors: Zade Bihag, Jay Patel, Nicole Hoover, Sean Robert McMahon, Vincent Lipari, William Lane Duvall, Jeffrey F. Mather, Christopher Kulman, Mohiuddin Cheema, Raymond McKay
Journal: Journal of the American College of Cardiology (2025)
RIGHT VENTRICULAR FUNCTION AS ASSESSED BY TRICUSPID ANNULAR PLANE SYSTOLIC EXCURSION IN PATIENTS UNDERGOING TRANSCATHETER TRICUSPID VALVE REPLACEMENT WITH EVOQUE VALVE
Authors: Omar Sami Abdelhai, Pedro Arturo Villablanca, Gautam Rangavajla, Tiberio M. Frisoli, Brian Patrick O’Neill, James Chihong Lee, Bryan Zweig, Georgi Fram, Felix Nguyen
Journal: Journal of the American College of Cardiology (2025)
SAFETY AND EFFICACY OF PERCUTANEOUS CORONARY INTERVENTION IN PATIENTS UNDERGOING TRANSCATHETER AORTIC VALVE IMPLANTATION
Authors: Sahib Singh, Tinaz Bhutta, Muhammad Asim Shabbir, Nidhish Tiwari, Kevin Bliden, Udaya Tantry, Paul A. Gurbel, Mohammed Kanjwal, Scott Lundgren
Journal: Journal of the American College of Cardiology (2025)
PHARMACODYNAMIC EFFECTS OF DIFFERENT TICAGRELOR MAINTENANCE DOSING REGIMENS WITH AND WITHOUT ASPIRIN IN PATIENTS WITH DIABETES MELLITUS: THE OPTIMUS (OPTIMIZING ANTIPLATELET THERAPY IN DIABETES MELLITUS)-7 STUDY
Authors: Francesco Franchi, Fabiana Rollini, Luis Ortega Paz, Latonya Been, Tala Al Saleh, Selina Durukan, Ekin Can Uzunoglu, Andrea Rivas, maryam Farahmandsadr, Madeline Mahowald, Siva Suryadevara, Calvin Y. Choi, Daniel Soffer, Martin M. Zenni, Dominick J. Angiolillo
Journal: Journal of the American College of Cardiology (2025)
SAFETY OF CONCOMITANT TRANSCATHETER AORTIC VALVE REPLACEMENT AND LEFT ATRIAL APPENDAGE OCCLUSION IN PATIENTS WITH ATRIAL FIBRILLATION: A META-ANALYSIS
Authors: Hritvik Jain, NANDAN PATEL, Muhammad Muneeb Arshad, Siddhant Passey, JYOTI JAIN, Khadija Amanullah, Faizan Ahmed, Muhammad Hazqeel Kazmi, Mayank Jha, Raheel Ahmed, Rozi Khan, Thomas Alexander
Journal: Journal of the American College of Cardiology (2025)
INTRACARDIAC ECHOCARDIOGRAPHY VERSUS TRANSESOPHAGEAL ECHOCARDIOGRAPHY FOR LEFT ATRIAL APPENDAGE CLOSURE DEVICE PLACEMENT: A SINGLE CENTER EXPERIENCE
Authors: Rosa N. Cruz Torres, Mohammad Hashim Jilani, Fatima Farrukh, Imran Arif, Charles R. Hattemer, Najam U. Saqib, Carla Macheledt, Vimal Mehta, Rishi Sukhija
Journal: Journal of the American College of Cardiology (2025)
SAFETY OF ISOLATED TRANSCATHETER TRICUSPID VALVE REPLACEMENT OR REPAIR COMPARED TO SURGERY IN PATIENTS WITH CHRONIC KIDNEY DISEASE
Authors: Mohammad Ali Sheffeh, Judy Sheffeh, Ider Oujamaa, Omar J. Baqal, Jacob Klein, Dua A. Malik, Mustafa Turkmani, M. Chadi Alraies
Journal: Journal of the American College of Cardiology (2025)
IMPACT OF CAROTID ARTERY STENOSIS ON OUTCOMES AFTER TRANSCATHETER AORTIC VALVE IMPLANTATION: AN UPDATED SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Theoni Theodoropoulou, Nikolaos Vythoulkas-Biotis, Anastasios Apostolos, Leonidas Koliastasis, Nikolaos Ktenopoulos, Sotirios Tsalamandris, George Latsios, Andreas G. Synetos, Maria I. Drakopoulou, Konstantinos Tsioufis, Konstantinos P. Toutouzas
Journal: Journal of the American College of Cardiology (2025)
Aortic Stenosis — When Valve Intervention Is Not Enough
Authors: Ori Ben-Yehuda
Journal: New England Journal of Medicine (2025)

With the aging of the population, aortic stenosis affects a growing number of patients, with a prevalence of 12.4% among persons who are at least 75 years of age, among whom 3.4% have severe aortic stenosis.1 Aortic stenosis is generally well tolerated for a prolonged period of time, even when the condition is severe, despite the increase in left ventricular afterload caused by the constricted outflow. However, once symptoms (typically, of heart failure) develop, the prognosis is poor.2 Given that aortic stenosis is primarily a mechanical problem that leads to the obstruction of left-heart outflow, medical therapy has a limited . . .
CATHETER DIRECTED ASPIRATION FOR RIGHT ATRIAL AND RIGHT VENTRICULAR MASSES: TRENDS IN USE OVER THE YEARS AND COMPARISON BETWEEN PERCUTANEOUS AND SURGICAL THROMBECTOMY FOR CLOT IN TRANSIT
Authors: Mukunthan Murthi, Andres Ernesto Quevedo Ramirez, Steve Attanasio, Gaurav Dhar, Neeraj Jolly, Aviral Vij
Journal: Journal of the American College of Cardiology (2025)
UTILITY OF INTRACARDIAC ECHOCARDIOGRAPHY IN EARLY COMMERCIAL TRANSCATHETER TRICUSPID VALVE REPLACEMENT
Authors: Georgi Fram, John Dawdy, Hussayn Alrayes, Leo Lai, Andrew Chou, Bryan Zweig, Sachin Parikh, Pedro Engel Gonzalez, Pedro Arturo Villablanca, Tiberio M. Frisoli, Brian Patrick O’Neill, James Chihong Lee
Journal: Journal of the American College of Cardiology (2025)
TREATMENT OF SEVERE RIGHT-SIDED INFECTIVE ENDOCARDITIS WITH MECHANICAL ASPIRATION VERSUS VALVE SURGERY: COMPARISON OF OUTCOMES AND INSIGHTS FROM A UNITED STATES REAL-WORLD DATABASE
Authors: Alexander J. Didier, Tyler Canova, Alan Fahoury, Rochell Issa, Kyle Nelson, Maryam Saleem, Marc A. Miller, Vivek Yerrapu Reddy
Journal: Journal of the American College of Cardiology (2025)
PREDICTION OF HEART FAILURE HOSPITALIZATION OR DEATH AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT
Authors: Bassim El-Sabawi, PRATIK MANANDHAR, Javed Butler, Philippe Genereux, Marc Dweck, Thomas Treibel, David J. Cohen, Nimesh Desai, Vinod H. Thourani, Wayne B. Batchelor, Michael J. Mack, Martin B. Leon, JoAnn Lindenfeld, Angela Lowenstern, Andrzej Kosinski, Sreekanth Vemulapalli, Brian R. Lindman
Journal: Journal of the American College of Cardiology (2025)
PERFORMANCE OF CONTEMPORARY RISK SCORES FOR TRANSCATHETER AORTIC VALVE REPLACEMENT: A META-ANALYSIS
Authors: Ankit Agrawal, Muhammad Majid, Aro Daniela Arockiam, Akiva Rosenzveig, Elio Haroun, Ahmad Safdar, Brian P. Griffin, Samir R. Kapadia, Tom Kai Ming Wang
Journal: Journal of the American College of Cardiology (2025)
PERCUTANEOUS MECHANICAL ASPIRATION OF CATHETER ASSOCIATED THROMBUS/ VEGETATIONS IN THE VENA CAVA: A CASE SERIES
Authors: Emaad Siddiqui, Sarthak Patel, Afif Hossain, Alfonso H. Waller, Abhishek Sharma, Marc Klapholz
Journal: Journal of the American College of Cardiology (2025)
ASSOCIATION OF OXIDIZED PHOSPHOLIPIDS WITH PLATELET ACTIVATION AND REACTIVITY AND LONG-TERM CARDIOVASCULAR OUTCOMES
Authors: Sotirios Tsimikas, Alexander Kille, Klaus Kaier, Thomas G. Nuehrenberg, Kilian Franke, Christian M. Valina, xiaohong yang, Gregor Leibundgut, Franz-Josef Neumann, Dirk Westermann
Journal: Journal of the American College of Cardiology (2025)
THREE-YEAR BLOOD PRESSURE REDUCTIONS AND CARDIOVASCULAR OUTCOMES AFTER RADIOFREQUENCY RENAL DENERVATION IN PATIENTS WITH HYPERTENSIVE METABOLIC SYNDROME: GLOBAL SYMPLICITY REGISTRY DEFINE
Authors: Michael Boehm, Markus P. Schlaich, Krzysztof Narkiewicz, Luis Ruilope, Bryan Williams, Roland E. Schmieder, Giuseppe Mancia, Minglei Liu, Felix Mahfoud
Journal: Journal of the American College of Cardiology (2025)
RIVAROXABAN AND WALKING ABILITY IN PATIENTS WITH SYMPTOMATIC PERIPHERAL ARTERY DISEASE AFTER LOWER EXTREMITY REVASCULARIZATION: INSIGHTS FROM VOYAGER PAD
Authors: Byung Gyu Kim, Manesh R. Patel, E. Sebastian Debus, Mark Nehler, Sonia Anand, Connie Ng Hess, Eva Muehlhofer, Lloyd Haskell, Scott D. Berkowitz, Rupert Bauersachs, Marc P. Bonaca
Journal: Journal of the American College of Cardiology (2025)
Dapagliflozin in Patients Undergoing Transcatheter Aortic-Valve Implantation
Authors: Sergio Raposeiras-Roubin, Ignacio J Amat-Santos, Xavier Rossello, Rocío González Ferreiro, Inmaculada González Bermúdez, Diego Lopez Otero, Luis Nombela-Franco, Livia Gheorghe, Jose L Diez, Carlos Baladrón Zorita, José A Baz, Antonio J Muñoz García, Victoria Vilalta, Soledad Ojeda-Pineda, José M de la Torre Hernández, Juan G Cordoba Soriano, Ander Regueiro, Pascual Bordes Siscar, Jorge Salgado Fernández, Bruno Garcia Del Blanco, Roberto Martín-Reyes, Rafael Romaguera, César Moris, Sergio García Blas, Juan A Franco-Peláez, Ignacio Cruz-González, Dabit Arzamendi, Nieves Romero Rodríguez, Felipe Díez-Del Hoyo, Santiago Camacho Freire, Francisco Bosa Ojeda, Juan C Astorga Burgo, Eduardo Molina Navarro, Juan Caballero Borrego, Valeriano Ruiz Quevedo, Ángel Sánchez-Recalde, Vicente Peral Disdier, Eduardo Alegría-Barrero, Javier Torres-Llergo, Gisela Feltes, José A Fernández Díaz, Carlos Cuellas, Gustavo Jiménez Britez, Juan Sánchez-Rubio Lezcano, Cristina Barreiro-Pardal, Iván Núñez-Gil, Emad Abu-Assi, Andrés Iñiguez-Romo, Valentín Fuster, Borja Ibáñez
Journal: New England Journal of Medicine (2025)

Sodium-glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of heart-failure admission among high-risk patients. However, most patients with valvular heart disease, including those undergoing transcatheter aortic-valve implantation (TAVI), have been excluded from randomized trials. We conducted this randomized, controlled trial in Spain to evaluate the efficacy of dapagliflozin (at a dose of 10 mg once daily) as compared with standard care alone in patients with aortic stenosis who were undergoing TAVI. All the patients had a history of heart failure plus at least one of the following: renal insufficiency, diabetes, or left ventricular systolic dysfunction. The primary outcome was a composite of death from any cause or worsening of heart failure, defined as hospitalization or an urgent visit, at 1 year of follow-up. A total of 620 patients were randomly assigned to receive dapagliflozin and 637 to receive standard care alone after TAVI; after exclusions, a total of 1222 patients were included in the primary analysis. A primary-outcome event occurred in 91 patients (15.0%) in the dapagliflozin group and in 124 patients (20.1%) in the standard-care group (hazard ratio, 0.72; 95% confidence interval [CI], 0.55 to 0.95; P = 0.02). Death from any cause occurred in 47 patients (7.8%) in the dapagliflozin group and in 55 (8.9%) in the standard-care group (hazard ratio, 0.87; 95% CI, 0.59 to 1.28). Worsening of heart failure occurred in 9.4% and 14.4% of the patients, respectively (subhazard ratio, 0.63; 95% CI, 0.45 to 0.88). Genital infection and hypotension were significantly more common in the dapagliflozin group. Among older adults with aortic stenosis undergoing TAVI who were at high risk for heart-failure events, dapagliflozin resulted in a significantly lower incidence of death from any cause or worsening of heart failure than standard care alone. (Funded by Instituto de Salud Carlos III and others; ClinicalTrials.gov number, NCT04696185.).
NO DIFFERENCE IN CLINICAL OUTCOMES BETWEEN INTRAVASCULAR LITHOTRIPSY AND ROTATIONAL ATHERECTOMY IN THE MANAGEMENT OF CORONARY ARTERY CALCIFICATION: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Abdul Mueez Alam Kayani, Muhammad Faiq Umar, Ricky E. Lemus-Zamora, Alan Garcia, Thomas Fretz
Journal: Journal of the American College of Cardiology (2025)