tbuckley/cabot-search huggingface dataset:
Differentialdiagnostische Symptomatologie von Krankheiten des Kindesalters: Klinische Vorlesungen
Authors: Werner Catel
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Physiology for Dental Students.
Authors: Arthur George Curzon-Miller
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Are you normal?
Authors: Bernice Kanner
Journal: BMJ (1997)

Find out how you fit into the American norm...  From sea to shining sea, Americans are remarkably alike, incredibly different, and just plain strange. In this clever, fun and fascinating peek into the private lives of real Americans, columnist Bernice Kanner shares a delicious slice of American pie with humorous facts like:  -Of the half of us who have pets at home, 45.5% allow them in the room during sex -One out of every four ice cream orders is vanilla; only one in nine is for chocolate -Four out of ten of us admit we've been so mad we've hurled footwear at another person -60% of men spit in public -One in ten people say they have seen a ghost -Almost one quarter of us regularly check ourselves out in store windows and mirrors -7 out of 100 Americans have flossed their teeth with their hair -Over 27% of people skip ahead to find out what will happen in a book before they finish it  Now you can join the fun!
Relationship between angiogenic markers and clinicopathologic factors/outcome in GOG-170D, a phase II trial of bevacizumab (Bev) in recurrent or persistent epithelial ovarian cancer (EOC) and primary peritoneal cancer (PPC)
Authors: E. S. Han, R. Burger, K. M. Darcy, M. W. Sill, B. E. Greer, J. I. Sorosky, J. P. Fruehauf
Journal: Journal of Clinical Oncology (2008)

5577 Background: Targeting angiogenesis pathways is becoming an important therapeutic option for patients with ovarian cancer. We explored the association between tumor markers of angiogenesis and clincopathologic factors/outcome in EOC/PPC patients treated with Bev. Methods: GOG-170D is a phase II study of recurrent or persistent EOC/PPC patients treated with Bev (15mg/kg IV q21days) until disease progression. Pre-cycle 1 tumor biopsies were analyzed for VEGF, thrombospondin-1 (TSP-1), and p53 overexpression by immunohistochemistry (IHC) with histoscore analysis. CD31 IHC hot spots in 3 separate 400x fields were measured to obtain microvessel density (MVD) counts. Marker expression was categorized as positive/negative (p53, TSP-1) or high/low (VEGF, CD31-MVD). Associations between biomarkers and clinicopathologic data/outcome were examined with Kendall's tau b, proportional hazards models, and Kaplan- Meier curves. Results: IHC data were evaluated in 43 out of 61 eligible patients. High CD31-MVD was associated with worse performance status (p=0.038) while the other markers were not associated with any of the clinicopathologic factors. Higher TSP-1 was associated with higher CD31-MVD (p=0.008) and lower VEGF (p=0.014). Although no obvious relationship was noted between the markers and response to Bev or progression-free survival (PFS), high CD31-MVD count was associated with an increased risk of death (hazard ratio [HR]=2.77, 95% confidence interval [CI]=1.35–5.68, p=0.005). After adjusting for age, GOG performance status, and platinum sensitivity, this relationship was maintained (HR=2.89, 95% CI=1.37–6.10, p=0.005). Median survival was 21 and 9 months for low compared with high CD31- MVD, respectively. Conclusions: High CD31-MVD counts, a surrogate marker for angiogenesis, was associated with worse overall survival in patients with recurrent or persistent EOC and PPC treated with Bev. None of the angiogenic markers including CD31-MVD count were associated with tumor response or PFS. Author Disclosure Employment or Leadership Consultant or Advisory Role Stock Ownership Honoraria Research Expert Testimony Other Remuneration Genentech Genentech
Nomenclature and Criteria for Diagnosis of Diseases of the Heart and Great Vessels.
Authors: Martin Dolgin
Journal: Annals of Internal Medicine (1974)

Since 1928, the New York Heart Association Functional Classification has been the system most widely accepted worldwide for assessing the severity of cardiac or cardiovascular disease, and evaluating the patient's response to treatment. This book sets out a diagnostic classification system for heart disease. The book is presented in six sections. The first four define the five components of any diagnosis: what is the cause? (aetiologic diagnosis); what is the structural anomaly? (anatomic diagnosis); what is the functional abnormality? (physiologic diagnosis); and how severe are the symptoms and what do the lab tests show? (functional capacity and objective assessment). These last two items, which summarize the clinical findings, constitute the two-part NYHA Classificabon for grading disease severity and tracking a patient's response to treatment. The fifth section discusses uncertain diagnosis. The sixth section, new to this edition, covers diagnostic techniques that have become standard since the last revision. Other changes in the ninth edition are a thorough updating of the biology of heart disease and a discussion on ventricular diastolic dysfunction. This edition restores the functional capacity component of the classification (dropped from the past two editions) and introduces an objective assessment category.
Organic Chemistry for Medical Students.
Authors: George Barger
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reconsolidation: Turning consciousness into memory
Authors: Mark Solms
Journal: Behavioral and Brain Sciences (2015)

Abstract The purpose of learning is not to maintain records but to generate predictions. Successful predictions remain implicit; only prediction errors (“surprises”) attract consciousness. This is what Freud had in mind when he declared that “consciousness arises instead of a memory-trace.” The aim of reconsolidation, and of psychotherapy, is to improve predictions about how to meet our needs in the world.
Bedside differentiation of depressive pseudodementia from dementia
Authors: C F Reynolds, C C Hoch, D J Kupfer, D J Buysse, P R Houck, J A Stack, D W Campbell
Journal: American Journal of Psychiatry (1988)

The authors analyzed the pretreatment clinical presentations of 14 patients with depressive pseudodementia and 28 patients with primary degenerative dementia as measured by the Mini-Mental State, the Blessed Dementia Rating Scale, and the Hamilton Rating Scale for Depression. They found that patients with pseudodementia showed significantly greater pretreatment early morning awakening, higher ratings of psychological anxiety, and more severe impairment of libido. Patients with dementia, however, showed significantly more disorientation to time, greater difficulty finding their way about familiar streets or indoors, and more impairment with dressing. The authors suggest that these findings be considered preliminary.
Abstract P169: Patients with an AED Applied by a Bystander in a Public Setting have a Strikingly Higher Frequency of VT/VF Than Observed Cardiac Arrests in the Home
Authors: Myron L Weisfeldt, Colleen Sitlani, Thomas Rea, Dianne Atkins, Tom P Aufderheide, Blair Bigham, Steven Brooks, Christopher Foerster, Joseph P Ornato, Judy Powell, Lois Van Ottingham, Laurie J Morrison
Journal: Circulation (2008)

Introduction: The overall incidence of ventricular tachycardia/ventricular fibrillation (VT/VF) as the first recorded electrical rhythm in out of hospital cardiac arrest (OOHCA) has declined from ~70% to ~25% over the last 30 years. This change has been attributed to primary and secondary prevention of cardiovascular disease and VT/VF. We evaluated whether the incidence of VT/VF as first recorded rhythm differed by location among bystander AED applied patients and EMS witnessed cardiac arrests. Methods: Prospective cohort study of non-traumatic cardiac arrest from December 2005 to April 2007 in the Resuscitation Outcomes Consortium database from 10 US and Canadian sites. The incidence of an initial shockable rhythm on AED or documented VT/VF was compared among bystander applied AED patients and EMS witnessed arrests in public versus private settings. Results: The first rhythm was known in 13,235 of 14,059 (94%) adult EMS-treated cardiac arrests. Of the 13,235 with known rhythms, 3436 (26%) had VT/VF. Among 1115 EMS-witnessed arrests, 61/161 (38%) had VT/VF in public settings and 224/954 (23%) in private settings. Similarly, for bystander AED applied in the private setting 39/114 (34%) were shocked. But, in contrast, 125/159 (79%) (P&lt;.001 vs all other) were shocked by the AED in the public setting. Witnessed arrests in both the private setting (vs public) and in EMS witnessed cases (vs bystander AED applied) were more likely to occur in older subjects and females. After adjusting for age and gender via logistic regression models, a significant difference in the odds of having a shockable rhythm in public versus private location of arrest remained in EMS-witnessed arrests (P&lt;0.005). The difference also remained in bystander AED applied arrests (P&lt;0.001) after adjusting for age, gender, and bystander-witnessed status. Conclusions: The incidence of VT/VF is far greater in the public setting particularly for bystander witnessed AED applied arrests. Patients in the private home setting, even for EMS observed arrests, are far less likely to benefit from AED application than bystander witnessed patients in the public setting. CPR strategies may need to be tailored by arrest location.
Know your school psychologist.
Authors: Wilma E. Hirst
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 2614: Thirty Five Percent of Children with Single Ventricle have Deep Venous Thromboses as Detected by Magnetic Resonance Venography
Authors: Gloria Perez, Edythe B Tham, Lesley G Mitchell, Michelle L Noga
Journal: Circulation (2008)

INTRODUCTION: Thrombotic events are a frequent complication in children with congenital heart disease undergoing staged palliative surgery and may preclude further cavopulmonary shunts. However, th...
PWE-075 Endoscopic radiofrequency ablation for high-grade dysplasia or intramucosal cancer in Barrett's oesophagus – results from the first 100 patients enrolled in the UK HALO radiofrequency ablation registry
Authors: J M Dunn, S Thorpe, G M Fullarton, H Smart, I Penman, P Patel, R Willert, M R Novelli, M B Banks, L B Lovat
Journal: Gut (2010)

<h3>Introduction</h3> The incidences of Barrett9s oesophagus (BE) and associated oesophageal adenocarcinoma are increasing rapidly in the UK. Radiofrequency ablation (RFA) with a circumferential balloon based device (CA) and endoscope-mounted focal ablation device (FA) are promising modalities for treating dysplasia arising in BE. <h3>Aim</h3> To determine the safety and efficacy of RFA for treating dysplastic BE in a UK patient cohort. <h3>Study Design</h3> Multicentre UK registry (seven teaching and private hospitals; treatment period from April 2007 to November 2009). Patients with histological evidence of dysplasia or intramucosal cancer (IMC) arising in BE confirmed by two specialist GI pathologists were included in the study. A prior endoscopic mucosal resection (EMR) was permitted, provided that residual dysplasia remained in the BE region for ablation. RFA was performed every 3 months with follow-up biopsy upon achieving either complete endoscopic eradication of BE or after four consecutive ablations. The primary endpoint was complete response for high-grade dysplasia (CR-HGD), dysplasia (CR-D) and intestinal metaplasia (CR-IM), defined as no biopsy showing each respective finding. <h3>Results</h3> A total of 106 patients (79% male, median age 69 years, interquartile range (IQR) 50–83 years) have been treated so far. Accrual rates now exceed 15 patients per quarter. 83 had HGD, 22 IMC, 1 LGD. Median length of BE was 6 cm (IQR 1–15 cm). 54% had prior EMR, 25% had previous photodynamic therapy (PDT) or argon plasma coagulation (APC). 42 patients have completed treatment with at least 1 follow-up biopsy session (median follow-up 4 months, IQR 2–24). Median number of treatments is 1 CA (IQR 0–3) and 1 FA (IQR 0–3). CR-HGD was achieved in 90% of patients, CR-D in 79% and CR-IM in 33%. There were eight new strictures, three mucosal injuries during RFA (1.5%) and one perforation (patient previously treated with PDT) (0.5%). <h3>Conclusion</h3> Reversal of IM is currently poor, but many of these patients have had multiple previous ablative therapies and may represent a particularly difficult group to treat. Despite this, radiofrequency ablation safely achieved a CR- HGD in 90% of patients treated within a UK multicentre registry. These data are similar to other registries.
Bacteriological Technique. A Laboratory Guide for Medical, Dental, and Technical Students.
Authors: J. W. H. Eyre
Journal: Annals of Internal Medicine (1931)

This well known laboratory guide is intended primarily for students of general bacteriology but is applicable also to the medical student. The methods are given in great detail and with unusual clarity. It is difficult to find any ordinary laboratory method in bacteriology that has been omitted. Indeed, the book is more of a reference manual for practical workers than a textbook for students.
Drug points: Anisocoria associated with selective serotonin reuptake inhibitors
Authors: J Barrett
Journal: BMJ (1994)

GARTMANN (Swiss Drug Monitoring Centre, write: We describe five cases of arthralgia associated with ome- prazole.In all cases the patients were treated with 20-40 mg omeprazole daily.A 27 year old woman was given omeprazole for a duodenal ulcer that was unresponsive to ranitidine.After 10 days she developed swelling of her fingers, knees, and ankles, with pruritus and erythema over the metacarpal joints.Treatment was stopped and symptoms disappeared within 10 days.
Children's Radiographic Technic.
Authors: Forrest E. Shurtleff
Journal: Annals of Internal Medicine (1952)

covers in excellent fashion the differential diagnosis of the acute abdomen.It affords the physician the background of information essential to evaluate an acute abdomen and to attain therapeutic judgment.It is small, compact, can be read with advantage in a few hours, and will serve as a handy reference book for student, general practitioner, and specialist alike.It is recommended for perusal or study by any physician encountering acute abdominal conditions in practice.It is a valuable contribution to medical literature and deseirves to be in the library of practicing physicians.
Survival impact of primary tumor resection in metastatic small intestine adenocarcinoma (SIA): Retrospective analysis of 44 cases treated with palliative chemotherapy
Authors: A. Kretzschmar, B. Kurzidim, M. Schuler, J. T. Hartmann, R. Hofheinz, M. Stahl, G. Folprecht, P. C. Thuss-Patience
Journal: Journal of Clinical Oncology (2008)

15588 Background: SIA is a rare disease (0.5/100.000/y). Limited data is available concerning the effect of palliative chemotherapy (pCT) in this disease. Resection of the primary tumour (PT) is not routinely performed if distant metastases (DM) are present. Methods: We evaluated the files of all pts with SIA who received at least one cycle of pCT. Pts were classified to have the initial PT or local recurrence (LR) surgically completely removed or not and whether they were offered a 2nd-line pCT in case of failure of 1st-line or not. Results: 44 pts, age 32–72, median (M) 60 were identified. The PT was: duodenum 24, jejunum 14, ileum 6. 21 pts were initially resected in curative intent and suffered a distant and/or local relapse after 1 - 104 months (mo), M 11 mo. When pCT was started for DM in 25 pts no local tumor was present whereas the remaining had PT/LR without DM (3) or both (16). Pts received a broad variety of fluoropyrimidine- based regimens in 1 to 4 lines (mainly colorectal-like protocols). Long lasting complete or partial remissions (12 - 136+ mo) in 1st- but also 2nd-line were observed in pts without PT/LR whereas the outcome was poor in general when local tumor was present. Survival was significantly longer in pts without PT/LR (M 40 mo) as compared to those with local tumor present (M 8 mo, p = 0.003 logrank). No obvious difference was observed whether the PT was resected in curative intent and DM occurred later or if palliative but complete resection of PT or LR was performed with DM present. 6 pts are still in remission. 18/38 pts with progressive disease on/after 1st-line received 2nd-line pCT (colorectal like regimens). If 2nd-line was offered survival was significant longer (M 26 mo vs 8 mo). Conclusions: In our series outcome of pts with metastatic SIA who have PT in situ and treated with pCT is comparable to that of other metastasized upper GI-malignancies. Our retrospective study supports the hypothesis that pCT in pt with metastatic SIA but no LT might be very effective. This means that even in palliative intent surgical local tumor control appears to be essential for a favourable outcome and should be considered. This is different to the situation in colorectal cancer. A prospective study of the issue is warranted. No significant financial relationships to disclose.
Die Reiztheorie und die modernen Behandlungsmethoden des Diabetes.
Authors: R. Kolisch
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Next-Generation Sequencing and Real-Time Quantitative PCR For Quantification Of Low-Level Minimal Residual Disease In Acute Lymphoblastic Leukemia Of Adults
Authors: Monika Brüggemann, Matthias Ritgen, Marco Ladetto, Francois Pepin, Heiko Trautmann, Victoria Carlton, Dieter Hoelzer, Nicola Gökbuget, Michael Kneba, Malek Faham, Christiane Pott
Journal: Blood (2013)
Multiple myeloma (MM) with deletion of 13q13 is characterized by increased bone marrow (BM) neovascularization - Implications for treatment of high-risk disease.
Authors: J Drach, J Ackermann, A Obermair, A Chott, K Fuchs, S Schreiber, R Konigsberg, H Kaufmann, E Urbauer, K Geissler, H Gisslinger, H Huber
Journal: Blood (1999)