FRIEDLÄNDER PNEUMONIA TREATED WITH STREPTOMYCIN; REPORT OF A CASE WITH PROMPT RECOVERY
Authors: Norman Learner, William R. Minnich
Journal: Annals of Internal Medicine (1946)

Case Reports1 September 1946FRIEDLÄNDER PNEUMONIA TREATED WITH STREPTOMYCIN; REPORT OF A CASE WITH PROMPT RECOVERYNORMAN LEARNER, WILLIAM R. MINNICHNORMAN LEARNERSearch for more papers by this author, WILLIAM R. MINNICHSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-25-3-516 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe introduction of streptomycin has provided a new antibiotic effective against many Gram negative organisms unaffected by penicillin. The Friedländer bacillus (Klebsiella pneumoniae) has been shown to be susceptible to streptomycin in vitro,1 but the effect of this agent on acute Friedländer pneumonia is not known.† Recently, the opportunity arose for just such a therapeutic trial. The patient responded so rapidly to streptomycin that a report was felt justified, especially since this type of pneumonia is so refractory to other drugs.CASE REPORTThe patient, a 36 year old white infantry soldier, sustained a penetrating shell fragment wound of the...Bibliography1. Unpublished data, Merck and Co., Inc., Rahway, N. J. Google Scholar2. ANDERSON DG: The treatment of infections with penicillin, New England Jr. Med., 1945, ccxxxii, 400. CrossrefGoogle Scholar3. STEBBINSROBINSON RBHJ: A method for determination of streptomycin in body fluids, Proc. Soc. Exper. Biol. and Med., 1945, lix, 255. CrossrefGoogle Scholar4. JULIANELLE LA: A biological classification of encapsulatus pneumoniae (Friedländer's bacillus), Jr. Exper. Med., 1926, xliv, 113. CrossrefGoogle Scholar5. SOLOMON S: Primary Friedländer pneumonia; Report of thirty-two cases, Jr. Am. Med. Assoc., 1937, cviii, 937. CrossrefGoogle Scholar6. PERLMANBULLOWA EJG: Primary bacillus Friedländer (Klebsiella pneumoniae) pneumonia; therapy of B. Friedländer B pneumonia, Arch. Int. Med., 1941, lxvii, 907. CrossrefGoogle Scholar7. HYDEHYDE LB: Primary Friedländer pneumonia, Am. Jr. Med. Sci., 1943, ccv, 660. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication May 23, 1946.†At the time this report was submitted we were not familiar with the paper of HERRELL, W. E., NICHOLS, D. R.: The clinical use of streptomycin: A study of 45 cases, Proc. Staff Meetings, Mayo Clin., 1945, xx, 449, in which the authors described two cases of Friedländer pneumonia treated with streptomycin. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byFriedländer's pneumonia with multiple lung abscesses: Recovery following the use of streptomycin and aureomycinSTREPTOMYCIN IN FRIEDLÄNDER PNEUMONIAPneumonia in infancy caused by Friedländer's bacillusStreptomycinStreptomycin Treatment of Pulmonary Infections 1 September 1946Volume 25, Issue 3Page: 516-520KeywordsBacillusDrugsKlebsiella pneumoniaePenicillinPneumoniaStreptomycin Issue Published: 1 September 1946 PDF downloadLoading ...