tbuckley/cabot-search huggingface dataset:
Deep Learning Uncovers Clinical Subphenotypes of Diabetic Kidney Disease Driven by Genetic Variation in Rac1 Pathway
Authors: Ishan Paranjpe, Xuan Wang, Nanditha Anandakrishnan, Weibin Zhou, Evren U. Azeloglu, John C. He, Girish N. Nadkarni
Journal: Journal of the American Society of Nephrology (2021)

Paranjpe, Ishan; Wang, Xuan; Anandakrishnan, Nanditha; Zhou, Weibin; Azeloglu, Evren U.; He, John C.; Nadkarni, Girish N. Author Information
More Severe Mitochondrial Injury at the Time of Diagnosis Is Associated with Poor Prognosis in Minimal Change Disease
Authors: Byung chul Yu, Moo Yong Park, Soo Jeong Choi, Seung D. Hwang, Jin kuk Kim
Journal: Journal of the American Society of Nephrology (2021)

Yu, Byung chul; Park, Moo Yong; Choi, Soo Jeong; Hwang, Seung D.; Kim, Jin kuk Author Information
The Dual Endothelin Angiotensin Receptor Antagonist (DEARA) Sparsentan Protects from Glomerular Hypercellularity and Associated Immune/Inflammatory Gene Network Activity in a Model of IgA Nephropathy
Authors: Colin Reily, Zina Moldoveanu, Tiziano Pramparo, Stacy D. Hall, Lea Novak, Radko Komers, Celia P. Jenkinson, Jan Novak
Journal: Journal of the American Society of Nephrology (2021)
Differential Cell Cycle and Kinase Activation in IgA1-Producing Cells from IgAN Patients and Healthy Controls Mediated by Cytokine Stimulation
Authors: Colin Reily, Dana Rizk, Jan Novak
Journal: Journal of the American Society of Nephrology (2021)

Journal of the American Society of Nephrology 32(10S):p 456, October 2021. | DOI: 10.1681/ASN.20213210S1456c
Defining Cell Type Specificity of TNF Targets in Nephrotic Syndrome
Authors: Phillip J. McCown, Sean Eddy, Fadhl Alakwaa, Jennifer L. Harder, Jamal El Saghir, Wenjun Ju, Matthias Kretzler, Laura H. Mariani
Journal: Journal of the American Society of Nephrology (2021)

McCown, Phillip J.; Eddy, Sean; Alakwaa, Fadhl; Harder, Jennifer L.; El Saghir, Jamal; Ju, Wenjun; Kretzler, Matthias; Mariani, Laura H.; Nephrotic Syndrome Study Network (NEPTUNE) Author Information
Targeted Release Formulation Budesonide (Nefecon) Selectively Reduces Circulating Levels of Chemokines Critical to Immune Cell Trafficking to Peyer Patches in IgA Nephropathy
Authors: Karen Molyneux, David H. Wimbury, Jasraj S. Bhachu, Masahiro Muto, Andrew M. Stone, Jonathan Barratt
Journal: Journal of the American Society of Nephrology (2021)
Serum and Glomerular Complement Components as Biomarkers in the First South Asian Prospective Longitudinal Observational IgA Nephropathy Cohort (GRACE-IgANI)
Authors: Suceena Alexander, Santosh Varughese, Athul Thomas, Jeethu J. Eapen, Elenjickal E. John, Anna T. Valson, Vinoi G. David, John Feehally, Jonathan Barratt, George John, Marc M. Seelen, Mohamed R. Daha
Journal: Journal of the American Society of Nephrology (2021)
Dual Tubular Par1a/b cKO Is Protective Against Renal Fibrosis
Authors: Vellia Zhou, Zhongfang Du, Kaye E. Brathwaite, Kimberly J. Reidy
Journal: Journal of the American Society of Nephrology (2021)

Zhou, Vellia; Du, Zhongfang; Brathwaite, Kaye E.; Reidy, Kimberly J. Author Information
The HIV Protease Inhibitor Darunavir Protects Against Diabetic Kidney Injury in Mice and Alters Stress Granule-Associated Signaling
Authors: Xiaobo Gao, Fnu Sonia, Heidi Karttunen, Buadi Tandoh, Michael J. Ross
Journal: Journal of the American Society of Nephrology (2021)

Gao, Xiaobo; Sonia, Fnu; Karttunen, Heidi; Tandoh, Buadi; Ross, Michael J. Author Information
The Role of Intestinal Flora in Cinnamaldehyde Alleviating Early Proteinuria in Diabetic Nephropathy
Authors: Huanhuan Yin, Xiaoxiao Shi, Yan Liu, Dan Yang, Limeng Chen
Journal: Journal of the American Society of Nephrology (2021)

Journal of the American Society of Nephrology 32(10S):p 249, October 2021. | DOI: 10.1681/ASN.20213210S1249a
Developing a Prediction Model for Incidence of Newly Detected CKD Among US Veterans, 2009-2018
Authors: Jennifer L. Bragg-Gresham, Brenda W. Gillespie, Karandeep Singh, Xiaosong Zhang, Yun Han, Diane Steffick, Vahakn Shahinian, William Weitzel, V. G. Vinod Vydiswaran, Tiffany C. Veinot, Susan T. Crowley, Rajiv Saran
Journal: Journal of the American Society of Nephrology (2021)
Risk Factors and Outcomes of Post-Transplant Erythrocytosis Among Adult Kidney Transplant Recipients: A Systematic Review and Meta-Analysis
Authors: Poemlarp Mekraksakit, Boonphiphop Boonpheng, Natnicha Leelaviwat, Samapon Duangkham, Anasua Deb, Kenneth Nugent, Wisit Cheungpasitporn
Journal: Journal of the American Society of Nephrology (2021)
CYP450: Protagonists in the Story of Diabetic Kidney Disease
Authors: Batoul Dia, Mohamad Noureldein, Sami Azar, Fuad N. Ziyadeh, Assaad Antoine Eid
Journal: Journal of the American Society of Nephrology (2021)

Dia, Batoul; Noureldein, Mohamad; Azar, Sami; Ziyadeh, Fuad N.; Eid, Assaad Antoine Author Information
Impact of Non-Pharmacological Interventions in Indigenous Populations with Diabetes Mellitus on Cardiovascular and Kidney Disease: A Scoping Review Using the REAIM Framework
Authors: Ikechi G. Okpechi, Shezel Muneer, Mohammed M. Tinwala, Anukul Ghimire, Maryam Khan, Naima Sultana, Feng Ye, Deenaz Zaidi, Aminu K. Bello
Journal: Journal of the American Society of Nephrology (2021)

Okpechi, Ikechi G.; Muneer, Shezel; Tinwala, Mohammed M.; Ghimire, Anukul; Khan, Maryam; Sultana, Naima; Ye, Feng; Zaidi, Deenaz; Bello, Aminu K. Author Information
Risk of Bleeding Associated with Direct Oral Anticoagulants Is Higher Among Patients with Concomitant Use of Diltiazem in Patients with and without CKD
Authors: Yunwen Xu, Alex R. Chang, Lesley A. Inker, Mara McAdams-DeMarco, Morgan Grams, Jung-Im Shin
Journal: Journal of the American Society of Nephrology (2021)
Nrf2 Activators Induce Inflammasome Attenuation: Possible Role in Diabetic Nephropathy
Authors: Ignacio J. Quevedo Romero, Andrea Carrasco Cremades, Laura H. Navarro, Pablo Pelegrin, Santiago Cuevas
Journal: Journal of the American Society of Nephrology (2021)

Quevedo Romero, Ignacio J.; Cremades, Andrea Carrasco; Navarro, Laura H.; Pelegrin, Pablo; Cuevas, Santiago; Molecular Inflammation Group (IMIB-Arrixaca) Author Information
Long Non-Coding RNA Profiles and Declining Kidney Function in Patients with Diabetes and CKD
Authors: Eiichiro Satake, Hiroki Kobayashi, Zaipul I Md Dom, Kristina V. O'Neil, Bozena Krolewski, Marcus G. Pezzolesi, Andrzej S. Krolewski
Journal: Journal of the American Society of Nephrology (2021)
Identification of Cell-Specific Transcriptomic Changes and Cross-Talk in Diabetic Mice with Podocyte-Specific Induction of KLF6 Using Single Nuclei RNA Sequencing
Authors: Bismark Owusu Frimpong, Nehaben A. Gujarati, Sandeep K. Mallipattu
Journal: Journal of the American Society of Nephrology (2021)

Frimpong, Bismark Owusu; Gujarati, Nehaben A.; Mallipattu, Sandeep K. Author Information
REVEAL-CKD: Prevalence of Undiagnosed Early CKD in France and Japan
Authors: Jean Blaise J. Virgitti, Toshiki Moriyama, Eric T. Wittbrodt, Salvatore Barone, Matthew Arnold, Supriya R. Kumar, Hungta (tony) Chen, Krister Järbrink, Navdeep Tangri
Journal: Journal of the American Society of Nephrology (2021)
Efficacy of Sodium Zirconium Cyclosilicate for Treatment of Acute Hyperkalemia in Solid Organ Transplant Recipients
Authors: Rachael B. Leek, Scott A. Rega, Irene D. Feurer, Beatrice P. Concepcion
Journal: Journal of the American Society of Nephrology (2021)

Poster: Transplantation: Clinical - Underrecognized Risk Factors, Traditional Considerations, and Outcomes
The Functional Role of Neat1 in Diabetic Kidney Disease
Authors: Rui Xue, Wai Han Yiu, Joseph C K Leung, Loretta Y.Y. Chan, Sydney C. Tang
Journal: Journal of the American Society of Nephrology (2021)

Xue, Rui; Yiu, Wai Han; Leung, Joseph C K; Chan, Loretta Y.Y.; Tang, Sydney C. Author Information
Role of Mast Cells in the Progression of Peritoneal Fibrosis in Rats with Chronic Renal Failure
Authors: Itsuro Kazama
Journal: Journal of the American Society of Nephrology (2021)

Journal of the American Society of Nephrology 32(10S):p 746, October 2021. | DOI: 10.1681/ASN.20213210S1746b
Family-Friendly, Work-Friendly, Home-Hemodialysis and In-Center Hemodialysis Hybrid: The First of Its Kind
Authors: Adam Locke, Macaulay A. Onuigbo
Journal: Journal of the American Society of Nephrology (2021)

Journal of the American Society of Nephrology 32(10S):p 311, October 2021. | DOI: 10.1681/ASN.20213210S1311a
Association of Kidney Function with Major Postoperative Events After Noncardiac Ambulatory Surgeries: A Population-Based Cohort Study
Authors: Tyrone Harrison, Brenda Hemmelgarn, Matthew T. James, Braden J. Manns, Marcello Tonelli, Mary E. Brindle, Shannon M. Ruzycki, Kelly B. Zarnke, James Wick, Paul E. Ronksley
Journal: Journal of the American Society of Nephrology (2021)
Clinical Significance of Plasma Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Levels to Assess the Cardiovascular Risk in Hemodialysis Patients
Authors: Yu ho Lee, So-young Lee, Hyeyun Jeong, Yang gyun Kim, Ju young Moon, Sangho Lee, Jin sug Kim, Kyung hwan Jeong, Shin-Young Ahn, Dong-Young Lee, Hyeon Seok Hwang
Journal: Journal of the American Society of Nephrology (2021)
Cardiac Arrests During Hemodialysis Among Maintenance Hemodialysis Patients in a Large Dialysis Network in India
Authors: Suresh Sankarasubbaiyan, Venkatraman Ganapathi Subraman, Mallikarjuna Gowda B. Gowda, Sataynarayana R. Puvvada, Vikram A. Sonawane, Kaparaboina K. Kumar, Mohammad S. Husain, Kamal D. Shah
Journal: Journal of the American Society of Nephrology (2021)

Sankarasubbaiyan, Suresh; Subraman, Venkatraman Ganapathi; Gowda, Mallikarjuna Gowda B.; Puvvada, Sataynarayana R.; Sonawane, Vikram A.; Kumar, Kaparaboina K.; Husain, Mohammad S.; Shah, Kamal D. Author Information
Parenteral Iron Therapy Alters Polarization of Kidney Macrophages and Mitigates Kidney Fibrosis in Mice
Authors: Edwin Patino, Divya Bhatia, Steven Z. Vance, Francesca Vinchi, Stefano Rivella, Mary E. Choi, Oleh M. Akchurin
Journal: Journal of the American Society of Nephrology (2021)
Coronary Artery Calcification Is a Risk Factor for Intradialytic Hypotension in Hemodialysis Patients
Authors: Sonoo Mizuiri, Yoshiko Nishizawa, Toshiki Doi, Kazuomi Yamashita, Kenichiro Shigemoto, Koji Usui, Michiko Arita, Takayuki Naito, Shigehiro Doi, Takao Masaki
Journal: Journal of the American Society of Nephrology (2021)
Implementing a Patient-Centric Educational Handout to Provide the Knowledge of Kidney Disease and Dialysis, Promote Self-Care, and Improve Quality of Life in Patients Starting Hemodialysis
Authors: Jennifer Griffiths, Kiran Shivaraj, Shruti Kore, Michael D. Klein, Savneek S. Chugh
Journal: Journal of the American Society of Nephrology (2021)

Griffiths, Jennifer; Shivaraj, Kiran; Kore, Shruti; Klein, Michael D.; Chugh, Savneek S. Author Information
Need and Preference Assessments for Renal Care and Comprehensive Pre-ESKD Education Services for Advanced CKD Veterans
Authors: Gajapathiraju Chamarthi, Zachary P. Purvis, Lina Ly, Jennifer Hale-Gallardo, Huanguang Jia, Ashutosh M. Shukla
Journal: Journal of the American Society of Nephrology (2021)
NT-ProBNP for Heart Function and Volume Status in Hemodialysis Patients
Authors: Kyung Ho Lee, Young seung Oh, Byung chul Yu, Moo Yong Park, Jin kuk Kim, Seung D. Hwang, Soo Jeong Choi
Journal: Journal of the American Society of Nephrology (2021)

Lee, Kyung Ho; Oh, Young seung; Yu, Byung chul; Park, Moo Yong; Kim, Jin kuk; Hwang, Seung D.; Choi, Soo Jeong Author Information
NGAL Is Necessary for Antigen-Presenting Cells Recruitment and Proteinuria in the Mouse Kidney with Ureteral Obstruction
Authors: Patricio A. Araos, Stefanny M. Figueroa, Orlando M. Rubio, Javier I. Reyes Osorio, Cristián A. Amador
Journal: Journal of the American Society of Nephrology (2021)

Araos, Patricio A.; Figueroa, Stefanny M.; Rubio, Orlando M.; Reyes Osorio, Javier I.; Amador, Cristián A.; Laboratorio de Fisiopatología Renal, Instituto de Ciencias Biomédicas Author Information
Use of Crit-Line to Reduce Intradialytic Hypotension in Hospitalized Patients Receiving Dialysis
Authors: Marissa A. Martin, Luis M. Perez, Anip Bansal, Jessica B. Kendrick
Journal: Journal of the American Society of Nephrology (2021)

Martin, Marissa A.; Perez, Luis M.; Bansal, Anip; Kendrick, Jessica B. Author Information
Green Hemodialysis: Is It Really Possible to Save Water and Plastic Without Affecting the Quality of the Treatment?
Authors: Ismael A. Gómez Ruiz, Geovana Martin-Alemañy, Juan M. Ardavin Ituarte, Rossana Olmedo Ocampo
Journal: Journal of the American Society of Nephrology (2021)

Gómez Ruiz, Ismael A.; Martin-Alemañy, Geovana; Ardavin Ituarte, Juan M.; Ocampo, Rossana Olmedo; Santa Carmen Author Information
Impact of Medication Reconciliation by a Dialysis Pharmacist
Authors: Summer Dyer, Linda Awdishu, Sally Rafie, Victoria T. Nguyen
Journal: Journal of the American Society of Nephrology (2021)

Journal of the American Society of Nephrology 32(10S):p 312, October 2021. | DOI: 10.1681/ASN.20213210S1312a
Health-Related Quality of Life and Depression Score Differences in Brazilian and US CKD Patients
Authors: Danwen Yang, Lisa Henn, Daniel G. Muenz, Brian Bieber, Antonio A. Lopes, Elodie Speyer, Bruce M. Robinson, Roberto Pecoits-Filho, Ronald L. Pisoni, Fredric O. Finkelstein
Journal: Journal of the American Society of Nephrology (2021)
Healthcare Costs Associated with Systemic Lupus Erythematosus (SLE) in the Year Prior to Diagnosis of ESKD: Real-World Evidence from Two Databases in the United States
Authors: Christopher F. Bell, Shirley Huang, Amy Guisinger
Journal: Journal of the American Society of Nephrology (2021)

Journal of the American Society of Nephrology 32(10S):p 738, October 2021. | DOI: 10.1681/ASN.20213210S1738a
Provider Recognition of Patient-Reported Symptoms in Patients on Maintenance Hemodialysis
Authors: Huei Hsun Wen, Kinsuk Chauhan, Steven G. Coca, Girish N. Nadkarni, Lili Chan
Journal: Journal of the American Society of Nephrology (2021)

Wen, Huei Hsun; Chauhan, Kinsuk; Coca, Steven G.; Nadkarni, Girish N.; Chan, Lili Author Information
F4/80hi Resident Macrophages Contribute to Cisplatin-Induced Kidney Fibrosis and M2 Polarization in C57BL/6 Mice
Authors: Sophia M. Sears, Alexis Vega, Mark A. Doll, Parag P. Shah, Levi J. Beverly, Leah J. Siskind
Journal: Journal of the American Society of Nephrology (2021)

Sears, Sophia M.; Vega, Alexis; Doll, Mark A.; Shah, Parag P.; Beverly, Levi J.; Siskind, Leah J. Author Information
Hydrophilic vs. Lipophilic Statin Treatments in Patients with CKD After Acute Myocardial Infarction: A Propensity Score-Matched Comparison
Authors: Jongho Kim, Soo-Young Yoon, Dae Kyu Kim, Shinyeong Kang, Jin sug Kim, Kyung hwan Jeong, Hyeon Seok Hwang
Journal: Journal of the American Society of Nephrology (2021)

Kim, Jongho; Yoon, Soo-Young; Kim, Dae Kyu; Kang, Shinyeong; Kim, Jin sug; Jeong, Kyung hwan; Hwang, Hyeon Seok Author Information
Fibrosis-4 Index May Predict Mortality and Non-Fatal Cardiovascular Events in ESKD Patients Starting Dialysis
Authors: Yeonhee Lee, Da won Kim, Seok Joon Shin, Hye Eun Yoon, Joo Eun Lee
Journal: Journal of the American Society of Nephrology (2021)

Lee, Yeonhee; Kim, Da won; Shin, Seok Joon; Yoon, Hye Eun; Lee, Joo Eun Author Information
Lactate Dehydrogenase A Influences Pro-Inflammatory Polarization of Murine Bone Marrow-Derived Macrophages
Authors: Gunars Osis, Yan Lu, Amie Traylor, Anna A. Zmijewska, Stephen Barnes, Anupam Agarwal
Journal: Journal of the American Society of Nephrology (2021)

Osis, Gunars; Lu, Yan; Traylor, Amie; Zmijewska, Anna A.; Barnes, Stephen; Agarwal, Anupam Author Information
Symptom Clusters in a Diverse Prospective Hemodialysis Cohort
Authors: Amy S. You, Sara S. Kalantar, Keith C. Norris, Rene Amel Peralta, Yoko Narasaki, Ronald A. Fischman, Michael A. Fischman, Avedik Semerjian, Zahra Azadbadi, Danh V. Nguyen, Kamyar Kalantar-Zadeh, Connie Rhee
Journal: Journal of the American Society of Nephrology (2021)
Single-Nucleus RNA-Sequencing Analysis Elucidates Intercellular Interactions Between Inflammatory Parenchymal Cells and Immune Cells in the Kidneys with Tertiary Lymphoid Tissues
Authors: Takahisa Yoshikawa, Akiko Oguchi, Yuki Sato, Takuya Yamamoto, Yasuhiro Murakawa, Motoko Yanagita
Journal: Journal of the American Society of Nephrology (2021)
Release of ATP from Renal Tubular Epithelial Cells via Connexin 43 Deteriorates Renal Fibrosis After Unilateral Ureteral Obstruction
Authors: Rui Zeng
Journal: Journal of the American Society of Nephrology (2021)

Journal of the American Society of Nephrology 32(10S):p 745, October 2021. | DOI: 10.1681/ASN.20213210S1745c
The Effect of Predilution Online Hemodiafiltration on Body Composition, Nutritional Status, and Mortality
Authors: Sonoo Mizuiri, Yoshiko Nishizawa, Aiko Okubo, Toshiki Doi, Kazuomi Yamashita, Kenichiro Shigemoto, Koji Usui, Michiko Arita, Takayuki Naito, Shigehiro Doi, Takao Masaki
Journal: Journal of the American Society of Nephrology (2021)
Prevalence and Demographic Correlates of Pain, Depression, Fatigue, and Readiness to Seek Treatment for These Symptoms in Hemodialysis Patients
Authors: Susan M. Devaraj, Jonathan Yabes, Maria-Eleni Roumelioti, Jennifer L. Steel, Sarah J. Erickson, Mark L. Unruh, Manisha Jhamb
Journal: Journal of the American Society of Nephrology (2021)
Dysregulation of Fatty Acid Binding Protein and Their Relationship with Inflammatory Biomarkers in ESRD
Authors: Emily Bontekoe, Vinod K. Bansal, Fakiha Siddiqui, Omer M. Iqbal, Jawed Fareed
Journal: Journal of the American Society of Nephrology (2021)

Bontekoe, Emily; Bansal, Vinod K.; Siddiqui, Fakiha; Iqbal, Omer M.; Fareed, Jawed Author Information
Users of a Web-Based Communications Platform for Care Coordination of Hospitalized Dialysis Patients
Authors: Laura Plantinga, Courtney E. Hoge, Janice P. Lea, Christopher M. O'Donnell, Ann E. Vandenberg, Kyle P. James, Tahsin Masud, Bernard G. Jaar, Carol A. Gray, Rich Mutell
Journal: Journal of the American Society of Nephrology (2021)
Improving Education and Satisfaction of Hemodialysis Patients Through Anonymous Feedback
Authors: Arun Rajasekaran, Anand Prakash, Spencer Hatch, Yan Lu, Abolfazl Zarjou
Journal: Journal of the American Society of Nephrology (2021)

Rajasekaran, Arun; Prakash, Anand; Hatch, Spencer; Lu, Yan; Zarjou, Abolfazl Author Information
The Active Ingredient in the Nuphar lutea Plant, 6,6′-Dihydroxythiobinupharidine (DTBN), Ameliorates Kidney Fibrosis, Inflammation, and Anemia in a Mouse Model of CKD
Authors: Jannat Khalilia, Daniel Landau, Jacob Gopas, Yael Segev
Journal: Journal of the American Society of Nephrology (2021)
Major Vault Protein Promotes Macrophage-to-Myofibroblast Transition and Tubulointerstitial Fibrosis in a Murine Model of CKD
Authors: Cheuk Yin Wong, Susan Yung, Caleb C. Chan, Tak Mao D. Chan
Journal: Journal of the American Society of Nephrology (2021)

Journal of the American Society of Nephrology 32(10S):p 747, October 2021. | DOI: 10.1681/ASN.20213210S1747c
Implementation and Effectiveness of a Supportive Care Learning Collaborative for Hemodialysis
Authors: Manjula Kurella Tamura, Margaret R. Stedman, Jialin Han, Steven M. Asch, Alvin H. Moss, Annette Aldous, Glenda Harbert, Amanda C. Nicklas, Dale Lupu, Laura Holdsworth
Journal: Journal of the American Society of Nephrology (2021)
Targeting Innate Immune-Polyamine Axis Prevents CKD-Associated Cardiac Hypertrophy
Authors: Ke Yang, Wenhao Han, Yingguo Zhu, Jinghong Zhao
Journal: Journal of the American Society of Nephrology (2021)

Yang, Ke; Han, Wenhao; Zhu, Yingguo; Zhao, Jinghong; Department of Nephrology, the Key Laboratory for the Prevention and Treatment of Chronic Kidney Disease of Chongqing, Chongqing Clinical Research Center of Kidney and Urology Diseases, Xinqiao Hospital, Army Medical University (Third Military Medical University) Author Information
The Effect of Atrasentan on Kidney and Heart Failure Outcomes by Baseline Albuminuria and Kidney Function: A Post Hoc Analysis of the SONAR Trial
Authors: Simke W. Waijer, Ron T. Gansevoort, George L. Bakris, Ricardo Correa-Rotter, Fan Fan Hou, Donald E. Kohan, Hirofumi Makino, John McMurray, Vlado Perkovic, Sheldon W. Tobe, Hans-Henrik Parving, Dick de Zeeuw, Hiddo J. L Heerspink
Journal: Journal of the American Society of Nephrology (2021)
Baseline Renal Function and Left Ventricular Assist Device Outcomes Among Patients with CKD
Authors: Muhammad Abdulbasit, Omar K. Salameh, Mujahed M. Dauleh, Ronald P. Miller, Umar Farooq, Naman Trivedi, Nasrollah Ghahramani
Journal: Journal of the American Society of Nephrology (2021)

Abdulbasit, Muhammad; Salameh, Omar K.; Dauleh, Mujahed M.; Miller, Ronald P.; Farooq, Umar; Trivedi, Naman; Ghahramani, Nasrollah Author Information
Feasibility of Allo-Hemodialysis: First Experience from Porcine Studies
Authors: Xin Wang, Amrish U. Patel, Anil K. Gothi, Dejan Nikolic, Alexander Heide, Jiaming Dong, Hao Zhang, Vaibhav Maheshwari, Nadja Grobe, K S Nayak, Peter Kotanko
Journal: Journal of the American Society of Nephrology (2021)
Utilization of the Tablo Hemodialysis System's Data Platform: An Analysis of 100,000 Acute Dialysis Treatments
Authors: Josh Schumacher, Brittany Lim, Michael A. Aragon
Journal: Journal of the American Society of Nephrology (2021)

Journal of the American Society of Nephrology 32(10S):p 311, October 2021. | DOI: 10.1681/ASN.20213210S1311c
Loss of Macrophage Mitofusin 2 but Not Mitofusin 1 Suppresses Mitochondrial Biogenesis and Promotes Kidney Fibrosis
Authors: Divya Bhatia, Allyson M. Capili, Kiichi Nakahira, Thangamani Muthukumar, Augustine M. Choi, Mary E. Choi
Journal: Journal of the American Society of Nephrology (2021)
Abstract P495: Gut Microbiome and Plasma Metabolome Signatures Are Associated With Systemic Inflammation in Children
Authors: Bruno Bohn, Myriam Doyon, Luigi Bouchard, Patrice Perron, Renee Guerin, Eric Masse, Marie-France Hivert, Noel T Mueller
Journal: Circulation (2024)

Introduction: Gut microbiota and microbial metabolites are hypothesized to influence health via systemic inflammation, but pediatric studies are lacking. We investigated associations of gut microbiota and plasma metabolome with inflammation in children aged 5-7. Hypothesis: Children with greater abundances of pro-inflammatory microbial taxa and metabolites have more systemic inflammation. Methods: We analyzed cross-sectional data from the community-based Gen3G cohort (Quebec), including children with 3 inflammation measures (IMs; plasminogen activator inhibitor 1, monocyte chemoattractant protein 1, tumor necrosis factor α), untargeted plasma metabolome (Metabolon platform) and gut microbiota (stool 16S rRNA sequencing) data at the 5-year visit. We log-transformed and standardized each IM, averaging them as an inflammation score (InfSc). We pareto-scaled log-transformed metabolites, imputing missing values as half the minimum detected. We selected 76 known bacterial metabolites a priori . We excluded metabolites detected in &lt;50% of samples and microbial amplicon sequence variants (ASVs) in &lt;10% of the samples or with &lt;0.1% overall proportion. We examined associations of ASVs and metabolites with IMs and InfSc using ANCOM-BC2 and linear regression, respectively, after multivariable adjustment (see Figure legend). FDR p-values &lt;0.05 were considered significant. Results: A total of 320 children (mean age 63±4 months, 47% female, 95% white) had IMs and metabolome data, and 146 had microbiota data. Of 335 ASVs tested, 59 were associated with InfSc and 154 with any IM (10 strongest associations in Figure A ). Of the 1038 total metabolites and 76 bacterial metabolites tested, 53 and 5 metabolites, respectively, were associated with InfSc and 80 and 10, respectively, with any IM (10 bacterial metabolites in Figure B ). Conclusions: Microbial ASVs and metabolites, including pro-inflammatory ones (e.g., P. succinatutens, lactate, kynurenine), were associated with systemic inflammation in 5yo children.