tbuckley/cabot-search huggingface dataset:
Omitting the Fifth Largest Subspecialty From the Medical Residents Survey?
Authors: Daniel Shalev, Gregg Robbins-Welty, Christian T. Sinclair
Journal: JAMA Internal Medicine (2024)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Evaluation of clinical prediction models (part 1): from development to external validation
Authors: Gary S Collins, Paula Dhiman, Jie Ma, Michael M Schlussel, Lucinda Archer, Ben Van Calster, Frank E Harrell, Glen P Martin, Karel G M Moons, Maarten van Smeden, Matthew Sperrin, Garrett S Bullock, Richard D Riley
Journal: BMJ (2024)

Evaluating the performance of a clinical prediction model is crucial to establish its predictive accuracy in the populations and settings intended for use. In this article, the first in a three part series, Collins and colleagues describe the importance of a meaningful evaluation using internal, internal-external, and external validation, as well as exploring heterogeneity, fairness, and generalisability in model performance.
Ophthalmoplegia With Isolated Extraocular Muscle Hypertrophy
Authors: Cathy Meng Fei Li, David Dongkyung Kim, Larry H. Allen
Journal: JAMA Neurology (2024)

A 60-year-old man is experiencing diplopia but no problems with visual acuity, pain, or other symptoms. A magnetic resonance image of the head shows abnormal thickening and T2 hyperintensity of the right lateral rectus muscle. What is your diagnosis?
Error in Table 4
Journal: JAMA Neurology (2024)

Pietro Iaffaldano, MD; Emilio Portaccio, MD; Giuseppe Lucisano, MScStat; Marta Simone, MD; Alessia Manni, MD; Tommaso Guerra, MD; Damiano Paolicelli, MD; Matteo Betti, MD; Ermelinda De Meo, MD; Luisa Pastò, MD; Lorenzo Razzolini, MD; Maria A. Rocca, MD; Laura Ferrè, MD; Vincenzo Brescia Morra, MD; Francesco Patti, MD; Mauro Zaffaroni, MD; Claudio Gasperini, MD; Giovanna De Luca, MD; Diana Ferraro, MD; Franco Granella, MD; Carlo Pozzilli, MD; Silvia Romano, MD; Paolo Gallo, MD; Roberto Bergamaschi, MD; Maria Gabriella Coniglio, MD; Giacomo Lus, MD; Marika Vianello, MD; Paola Banfi, MD; Alessandra Lugaresi, MD; Rocco Totaro, MD; Daniele Spitaleri, MD; Eleonora Cocco, MD; Franco Di Palma, MD; Davide Maimone, MD; Paola Valentino, MD; Valentina Torri Clerici, MD; Alessandra Protti, MD; Giorgia Teresa Maniscalco, MD; Giuseppe Salemi, MD; Ilaria Pesci, MD; Umberto Aguglia, MD; Vito Lepore, MD; Massimo Filippi, MD; Maria Trojano, MD; Maria Pia Amato, MD; Italian Multiple Sclerosis Register; Elisabetta Ferraro; Francesco O. Logullo; Girolama A. Marfia; Roberto Bombardi; Davide Nasuelli; Paolo Bellantonio; Milena De Riz; Paola Gazzola; Guido Cavaletti; Matilde Inglese; Antonella Conte; Gioacchino Tedeschi; Alessia Di Sapio; Alessandro Leone; Sara Montepietra; Bruno Marini; Maurizia Gatto; Maria Sessa; Maria T. Ferrò; Augusto Rini; Daniela Cargnelutti; Massimiliano Mirabella; Alessandro Burlina; Carlo Avolio; Paola Cavalla; Marco Rovaris; Bonaventura Ardito; Carlo Piantadosi; Paolo A. Confalonieri; Raffaella Clerici; Silvia Strumia; Francesca De Robertis; Rocco Quatrale; Leonardo Sinisi; Cristina Fioretti; Vincenzo Di Lazzaro; Sebastiano Bucello; Luca Mancinelli; Giuseppe Ribizzi; Roberto Zarbo; Luigi M. E. Grimaldi; Francesco Corea; Vincenzo Sidoti; Luca Massacesi; Roberto Balgera; Marcello C. Romano; Francesco D'Andrea; Anna Luisa Ancona; Matteo Pizzorno; Steno Rinalduzzi; Francesco Passantino; Lorenzo Capone; Marta Bianchi; Simonetta Venturi; Giuseppe Trivelli; Giampaolo Brichetto; Silvia Fermi; Placido Bramanti; Rosa Iodice; Maria Luisa Piras; Maria Grazia Celani; Paolo Barone; Tiziana Tassinari; Annamaria Marson; Marinella Clerico; Paola Banfi; Claudio Solaro
Omitting the Fifth Largest Subspecialty from the Medical Residents Survey?—Reply
Authors: Neha Paralkar, Nancy LaVine, Lauren Block
Journal: JAMA Internal Medicine (2024)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Facts and Hopes on Chimeric Cytokine Agents for Cancer Immunotherapy
Authors: Zhenhua Ren, Xuhao Zhang, Yang-Xin Fu
Journal: Clinical Cancer Research (2024)

Abstract Cytokines are key mediators of immune responses that can modulate the antitumor activity of immune cells. Cytokines have been explored as a promising cancer immunotherapy. However, there are several challenges to cytokine therapy, especially a lack of tumor targeting, resulting in high toxicity and limited efficacy. To overcome these limitations, novel approaches have been developed to engineer cytokines with improved properties, such as chimeric cytokines. Chimeric cytokines are fusion proteins that combine different cytokine domains or link cytokines to antibodies (immunocytokines) or other molecules that can target specific receptors or cells. Chimeric cytokines can enhance the selectivity and stability of cytokines, leading to reduced toxicity and improved efficacy. In this review, we focus on two promising cytokines, IL2 and IL15, and summarize the current advances and challenges of chimeric cytokine design and application for cancer immunotherapy. Most of the current approaches focus on increasing the potency of cytokines, but another important goal is to reduce toxicity. Cytokine engineering is promising for cancer immunotherapy as it can enhance tumor targeting while minimizing adverse effects.
Development of a Strategic Initiative at MD Anderson Cancer Center to Improve Outcomes in Immune-Related Adverse Events
Authors: Sarah E. Fayle, Nicolas L. Palaskas, Bilal A. Siddiqui, Jennifer L. McQuade, Jamie S. Lin, Sumit K. Subudhi, Anisha B. Patel, Robert R. Jenq, Amishi Y. Shah, Amy R. Spelman, Mianen Sun, Bettina H. Marble, Yinghong Wang
Journal: Journal of the National Comprehensive Cancer Network (2024)

Immune checkpoint inhibitors (ICIs) have transformed the treatment paradigm for many cancer types. The clinical use of ICIs is increasing rapidly, including in combinations associated with increased risk of toxicities, termed “immune-related adverse events” (irAEs). Therefore, MD Anderson Cancer Center (MDACC) in Houston, Texas has proactively responded by developing a priority endeavor known as the Immuno-Oncology Toxicity (IOTOX) initiative. This strategic initiative aims to facilitate the seamless integration of key domains: (1) standardized clinical practice and innovative decision toolsets; (2) patient and provider education; and (3) a comprehensive clinical and translational research platform. The ultimate goal of this initiative is to develop and disseminate clinical best practices and biologic insights into irAEs to improve outcomes of patients with irAEs at MDACC and in the wider oncology community.
Diminishing Mortality Benefit of Cancer Screening With Improvements in Treatment
Authors: Ismail Jatoi
Journal: JAMA Internal Medicine (2024)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Does carbon dioxide gas-induced pneumothorax and one-lung ventilation really have similar oncological outcomes in minimally invasive esophagectomy?
Authors: Kexun Li, Jie Mao, Yunchao Huang
Journal: International Journal of Surgery (2024)

Department of Thoracic Surgery I, Key Laboratory of Lung Cancer of Yunnan Province, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Cancer Center of Yunnan Province, Kunming, China Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding Author. Address: Department of Thoracic Surgery I, Key Laboratory of Lung Cancer of Yunnan Province, Yunnan Cancer Hospital, The Third Affiliated Hospital of Kunming Medical University, Cancer Center of Yunnan Province, Kunming, China 519 Kunzhou Road, Xishan District, Kunming City, Yunnan Province, China. Tel: +8618040459226. Fax: 0871-65922937. E-mail address: [email protected] (Y. Huang). This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0/
Hypotony Failure Criteria in Glaucoma Surgical Studies and Their Influence on Surgery Success
Authors: Alessandro Rabiolo, Giacinto Triolo, Daniela Khaliliyeh, Sang Wook Jin, Esteban Morales, Alessandro Ghirardi, Nitin Anand, Giovanni Montesano, Gianni Virgili, Joseph Caprioli, Stefano De Cillà
Journal: Ophthalmology (2024)
Unraveling Wavy ST Segments—An Unusual Case of Syncope
Authors: Kimberly L. Yan, Robert T. Short, Nora F. Goldschlager
Journal: JAMA Internal Medicine (2024)

This case report describes a patient in their 60s with gastroesophageal reflex disease who presented to the emergency department after loss of consciousness during dinner and daily intermittent chest discomfort.
Enhancer of Zeste Homolog 2 Inhibitor SHR2554 in Relapsed or Refractory Peripheral T-cell Lymphoma: Data from the First-in-Human Phase I Study
Authors: Yuqin Song, Zhengming Jin, Zhi-Ming Li, Yanyan Liu, Lanfang Li, Chuan He, Hang Su, Hui Zhou, Kunyan Li, Siguo Hao, Xuelan Zuo, Jianyuan Wu, Dengju Li, Meng Wu, Xiuhua Sun, Junyuan Qi, Zhen Cai, Zengjun Li, Yijing Li, Yanhua Huang, Jie Shen, Zhenyu Xiao, Jun Zhu
Journal: Clinical Cancer Research (2024)

Patients with peripheral T-cell lymphomas (PTCL) in the relapsed or refractory (r/r) setting have only a limited number of therapies available, and the prognosis is extremely poor. SHR2554 is an oral inhibitor against EZH2, a rational therapeutic target for lymphomas.
Using multiple real-world dermoscopic photographs of one lesion improves melanoma classification via deep learning
Authors: Achim Hekler, Roman C Maron, Sarah Haggenmüller, Max Schmitt, Christoph Wies, Jochen S Utikal, Friedegund Meier, Sarah Hobelsberger, Frank F Gellrich, Mildred Sergon, Axel Hauschild, Lars E French, Lucie Heinzerling, Justin G Schlager, Kamran Ghoreschi, Max Schlaak, Franz J Hilke, Gabriela Poch, Sören Korsing, Carola Berking, Markus V Heppt, Michael Erdmann, Sebastian Haferkamp, Konstantin Drexler, Dirk Schadendorf, Wiebke Sondermann, Matthias Goebeler, Bastian Schilling, Jakob N Kather, Eva Krieghoff-Henning, Titus J Brinker
Journal: Journal of the American Academy of Dermatology (2024)
Single-cell and spatial profiling identify three response trajectories to pembrolizumab and radiation therapy in triple negative breast cancer
Authors: Stephen L. Shiao, Kenneth H. Gouin, Nathan Ing, Alice Ho, Reva Basho, Aagam Shah, Richard H. Mebane, David Zitser, Andrew Martinez, Natalie-Ya Mevises, Bassem Ben-Cheikh, Regina Henson, Monica Mita, Philomena McAndrew, Scott Karlan, Armando Giuliano, Alice Chung, Farin Amersi, Catherine Dang, Heather Richardson, Wonwoo Shon, Farnaz Dadmanesh, Michele Burnison, Amin Mirhadi, Zachary S. Zumsteg, Rachel Choi, Madison Davis, Joseph Lee, Dustin Rollins, Cynthia Martin, Negin H. Khameneh, Heather McArthur, Simon R.V. Knott
Journal: Cancer Cell (2024)
The motivating effect of monetary over psychological incentives is stronger in WEIRD cultures
Authors: Danila Medvedev, Diag Davenport, Thomas Talhelm, Yin Li
Journal: Nature Human Behaviour (2024)

Abstract Motivating effortful behaviour is a problem employers, governments and nonprofits face globally. However, most studies on motivation are done in Western, educated, industrialized, rich and democratic (WEIRD) cultures. We compared how hard people in six countries worked in response to monetary incentives versus psychological motivators, such as competing with or helping others. The advantage money had over psychological interventions was larger in the United States and the United Kingdom than in China, India, Mexico and South Africa ( N = 8,133). In our last study, we randomly assigned cultural frames through language in bilingual Facebook users in India ( N = 2,065). Money increased effort over a psychological treatment by 27% in Hindi and 52% in English. These findings contradict the standard economic intuition that people from poorer countries should be more driven by money. Instead, they suggest that the market mentality of exchanging time and effort for material benefits is most prominent in WEIRD cultures.
Tecovirimat for Mpox—Promise and Limitations
Authors: Jason Zucker, William A. Fischer, Timothy Wilkin
Journal: JAMA Internal Medicine (2024)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Comments on Sports Participation and Transgender Youths
Authors: Gregory A. Brown, Mary I. O’Connor, Michael G. Parker
Journal: JAMA Pediatrics (2024)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Pediatrics HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Pediatrics journal
Targeting SRSF3 restores immune mRNA translation in microglia/macrophages following cerebral ischemia
Authors: Reza Rahimian, Revathy Guruswamy, Hejer Boutej, Pierre Cordeau, Yuan Cheng Weng, Jasna Kriz
Journal: Molecular Therapy (2024)

We recently described a novel ribosome-based regulatory mechanism/checkpoint that controls innate immune gene translation and microglial activation in non-sterile inflammation orchestrated by RNA binding protein SRSF3. Here we describe a role of SRSF3 in the regulation of microglia/macrophage activation phenotypes after experimental stroke. Using a model-system for analysis of the dynamic translational state of microglial ribosomes we show that 24 h after stroke highly upregulated immune mRNAs are not translated resulting in a marked dissociation of mRNA and protein networks in activated microglia/macrophages. Next, microglial activation after stroke was characterized by a robust increase in pSRSF3/SRSF3 expression levels. Targeted knockdown of SRSF3 using intranasal delivery of siRNA 24 h after stroke caused a marked knockdown of endogenous protein. Further analyses revealed that treatment with SRSF3-siRNA alleviated translational arrest of selected genes and induced a transient but significant increase in innate immune signaling and IBA1+ immunoreactivity peaking 5 days after initial injury. Importantly, delayed SRSF3-mediated increase in immune signaling markedly reduced the size of ischemic lesion measured 7 days after stroke. Together, our findings suggest that targeting SRSF3 and immune mRNA translation may open new avenues for molecular/therapeutic reprogramming of innate immune response after ischemic injury.
An Updated Equitable Model of Readiness for Transition to Adult Care
Authors: Kemar V. Prussien, Lori E. Crosby, Haley L. Faust, Lamia P. Barakat, Janet A. Deatrick, Kim Smith-Whitley, Lisa A. Schwartz
Journal: JAMA Pediatrics (2024)

Importance Despite elevated health risks during young adulthood, many adolescents and young adults with serious health care needs face barriers during the transfer to an adult specialty practitioner, and health disparities may occur during the transition. Objective To validate the content of an updated Social-Ecological Model of Adolescent and Young Adult Readiness for Transition to Promote Health Equity (SMART-E) in a group of adolescents and young adults with sickle cell disease (SCD) and their supports. Design, Setting, and Participants Health equity framework components were reviewed. Systems of power (eg, institutional and practitioner bias) and environments or networks (eg, peer or school support) were added as SMART-E preexisting factors, and health literacy was included within readiness factors. Adolescents and young adults aged 16 to 29 years with SCD, caregivers, and practitioners participated in this convergent, mixed-methods study within Children’s Hospital of Philadelphia between January and August 2022. Main Outcomes and Measures Content validity was assessed through nominations of top 3 most important transition barriers prior to interviews and focus groups, ratings on importance of SMART-E factors (0-4 scale; ratings &amp;amp;gt;2 support validity) after interviews and focus groups, nominations of 3 most important factors for transition and for health equity, and qualitative content analysis of interview transcripts. Results The study enrolled 10 pediatric adolescents and young adults (mean [SD] age, 18.6 [2.9] years; 4 female and 6 male), 10 transferred adolescents and young adults (mean [SD] age, 22.9 [2.1] years; 8 female and 2 male), 9 caregivers (mean [SD] age, 49.8 [8.7] years; 5 female and 4 male), and 9 practitioners (mean [SD] age, 45.6 [10.5] years; 8 female and 1 male). Quantitative ratings supported the content validity of SMART-E and met established criteria for validity. Systems of power was the most endorsed transition barrier (14 of 38 participants) reported prior to interviews and focus groups. After the interview, participants endorsed all SMART-E factors as important for transition, with new factors systems of power and environments and networks rated at a mean (SD) 2.8 (1.23) and 3.1 (0.90), respectively, on a 0 to 4 scale of importance. The most important factors for transition and equity varied by participant group, with all factors being endorsed, supporting the comprehensiveness of SMART-E. Qualitative data corroborated quantitative findings, further supporting validity, and minor modifications were made to definitions. Conclusions and Relevance SMART-E obtained initial content validation with inclusion of health equity factors for adolescents and young adults with SCD, caregivers, and practitioners. The model should be evaluated in other populations of adolescents and young adults with chronic disease.
A medium chain fatty acid, 6-hydroxyhexanoic acid (6-HHA), protects against obesity and insulin resistance
Authors: Sara C. Sebag, Meihua Hao, Qingwen Qian, Chawin Upara, Qiong Ding, Min Zhu, Jeffrey A. Banas, Huojun Cao, Liu Hong, Ling Yang
Journal: Acta Pharmaceutica Sinica B (2024)
How environmental impact is considered in economic evaluations of critical care: a scoping review
Authors: Alayna Carrandi, Christina Nguyen, Wai Chung Tse, Colman Taylor, Forbes McGain, Kelly Thompson, Martin Hensher, Scott McAlister, Alisa M. Higgins
Journal: Intensive Care Medicine (2024)

Health care is a major contributor to climate change, and critical care is one of the sector's highest carbon emitters. Health economic evaluations form an important component of critical care and may be useful in identifying economically efficient and environmentally sustainable strategies. The purpose of this scoping review was to synthesise available literature on whether and how environmental impact is considered in health economic evaluations of critical care.