tbuckley/cabot-search huggingface dataset:
Impact of Computer-Aided Detection on Endoscopists' Learning Curve for Adenoma Detection: A Prospective Observational Study
Authors: M Misawa, S E Kudo, T Okumura, Y Ide, S Kato, T Shibuya, Y Minegishi, Y Kouyama, Y Ogawa, Y Maeda, K Ichimasa, T Hayashi, K Wakamura, Y Mori, T Baba
Journal: Endoscopy (2025)
Early Chronic Pancreatitis (CP) and Factors Associated with the Long-Term Progression of the Disease
Authors: Y Dominguez-Novoa, J Iglesias-Garcia, J Lariño Noia, X F Martinez-Seara, P Miguez-Sanchez, L Nieto-Garcia, MD S Porto-Silva, J E Dominguez-Munoz
Journal: Endoscopy (2025)
Unveiling the Potential of Artificial Intelligence in Pan-intestinal Capsule Endoscopy: A Paradigm Shift for GI Diagnostics
Authors: B Rosa, M Mascarenhas Saraiva, J Afonso, T Cúrdia Gonçalves, F Mendes, M J Moreira, M Martins, F Dias De Castro, T Ribeiro, P Marílio Cardoso, M J Almeida, J Mota, J Ferreira, M Guilherme, J Cotter
Journal: Endoscopy (2025)
Endo-Histo Foundational Fusion Model: A Novel Artificial Intelligence Approach for Predicting Histologic Remission and Early Response to Therapy in a Phase 2 Ulcerative Colitis Clinical Trial
Authors: M Iacucci, G Santacroce, P Meseguer, R Del Amor, A Diéguez, B B Kolawole, U Chaudhari, I Zammarchi, B Hayes, R Crotty, D Zardo, Y Maeda, M Puga-Tejada, I Ditonno, V Vadori, L Burke, K T Gottlieb, C Owen, W J Eastman, S Ghosh, E Grisan, V Naranjo
Journal: Endoscopy (2025)
Patient-reported experience measures of EUS-guided and percutaneous liver biopsy. A prospective observational study
Authors: F Sanoubara, D Khalil, M Kimmann, J Gödiker, J Schulz, Z Wang, S Letmathe, S N Reinartz Groba, F Weppelmann, J A Meier, B Braden, W Laleman, J Trebicka, M Praktiknjo
Journal: Endoscopy (2025)
Predictive value of the Glasgow-Blatchford Score in predicting clinical outcomes and intervention in patients with acute Lower GI Bleeding: experience of a Tunisian tertiary center
Authors: I Lassoued, A Gnaba, N Elleuch, A Derbel, H Jaziri, D Wafa, A Braham, A Ben Slama, H Aya, M Ksiaa
Journal: Endoscopy (2025)
Efficacy and Safety of Endoscopic Ultrasound-Guided Gallbladder Drainage (EUS-GBD) as Bridge Therapy in Resectable Pancreatic Neoplasms After Failed ERCP
Authors: M Dura Gil, P Pérez Longo, H Martín Hortega, N Gendive Martín, C Ibarra Ponce De León, V González-Pinto, C Gil Garcia Ollauri, R Saá ÁLvarez, I Casado Morentín
Journal: Endoscopy (2025)
Underwater versus CO₂ Environment in Endoscopic Submucosal Dissection: A Propensity Score-Matched Analysis for Large Nonpedunculated Colorectal Polyps
Authors: R de Sire, A Capogreco, D Massimi, L Alfarone, L Brandaleone, V Vadalà, F Minini, M Spadaccini, C Hassan, R Maselli, A Repici
Journal: Endoscopy (2025)
Standardizing EUS-guided Gastroenterostomy: a Delphi consensus on technical steps and adverse events management
Authors: G Vanella, R Leone, F Frigo, M Bronswijk, R L van Wanrooij, Y I Chen, K F Binmoeller, M Perez-Miranda, P Chalal, M Jovani, A Tyberg, E Perez-Cuadrado-Robles, M Barthet, P Deprez, M Kahaleh, D Adler, M A Khashab, A Y Teoh, T Itoi, S Lakhtakia, R Kunda, S Van der Merwe, P Arcidiacono
Journal: Endoscopy (2025)
Pilot Study of a Novel Lumen-Apposing Metal Stent (LAMS) for Endoscopic Ultrasound-Guided Procedures in Porcine Models
Authors: M Benedetto, D Paduano, G franchellucci, F Auriemma, D Ramai, A Larghi, D De Deo, F Antonio, A Repici
Journal: Endoscopy (2025)
Technical Safety And Diagnostic Accuracy Of AI-Assisted Digital Single Operator Cholangioscopy During Real-time Assessment Of Indeterminate Biliary Strictures: The ARTICO Multicentric, Randomized, Controlled, Crossover Diagnostic Accuracy Trial
Authors: C Robles-Medranda, J Baquerizo-Burgos, J C Mendez, M Puga-Tejada, M Egas-Izquierdo, J Murillo, C Elias-Berrezueta, D Tabacelia, M Arevalo-Mora, J Alcivar-Vasquez, D Cunto
Journal: Endoscopy (2025)
Long-term Outcomes of EUS-guided Gastroenterostomy (LONG-RANGE study): a prospective cohort study tracking symptoms recurrence, reintervention timelines and stent changes over time
Authors: G Vanella, F Frigo, F Perelli, R Leone, P Maisonneuve, S Partelli, F Aleotti, G Orsi, M Macchini, G Balzano, M Reni, M Falconi, G Capurso, P Arcidiacono
Journal: Endoscopy (2025)
Artificial Intelligence for Automatic Detection and Differentiation of Anal HPV-related Dysplastic Lesions: An Interoperable Multicentric Study
Authors: M Martins, M Mascarenhas, S Lucas, L Barroso, T Manzione, A Javed, P Marílio Cardoso, F Mendes, M J Almeida, J Mota, N Fathallah, N Sidney, J Ferreira, M Guilherme, V D Parades
Journal: Endoscopy (2025)
The association between heatmap position and the diagnostic accuracy of artificial intelligence algorithms for the characterization of colorectal polyps
Authors: A Thijssen, N Dehghani, RW M Schrauwen, ET P Keulen, EJ A Rondagh, MH P Van Avesaat, K Soufidi, A Reumkens, PH A Bours, QE W Van Der Zander, PH N De With, B Winkens, F Van Der Sommen, E J Schoon
Journal: Endoscopy (2025)
Automatic Endoscopic Gastroplasty For The Treatment Of Obesity And Associated Comorbidities: An Interim Analysis Of A Prospective Clinical Trial
Authors: M V Matteo, B Vincenzo, V Pontecorvi, L Gualtieri, M De Siena, G Carlino, G Giannetti, I Felici, C Chiarini, A Iaconelli, C Massari, N Antonini, M Angeletti, C Spada, I Boskoski
Journal: Endoscopy (2025)
Endoscopic Ultrasound-Guided Double Drainage: Hepaticogastric and Anterograde Transpapillary Approaches for Malignant Distal Biliary Obstruction – What Are the Benefits?
Authors: E Perez-Cuadrado-Robles, J Antraygues, L Lukenga, H Alric, E Tenorio Gonzalez, T Boeken, E Ragot, H Benosman, C Cellier
Journal: Endoscopy (2025)
RNA-sequencing on EUS-acquired tissue of pancreatic cancer is feasible and allows identification of biomarkers of prognosis and of response to intensified chemotherapy
Authors: L Archibugi, C Fortunato, P Lazzano, R Ponz de Leon Pisani, L De Carolis, G Lauri, M Tacelli, P Zaccari, M C Petrone, G Rossi, L Apadula, G Vanella, C Sette, C Doglioni, M Falconi, M Reni, P Arcidiacono, G Capurso
Journal: Endoscopy (2025)
Second Lesions Occurring within the same belt-like region along the short axis of the stomach as Primary Lesions “BELT: Born Equal Line Tumors”: A Retrospective Clinicopathological Study of Early Gastric Cancer and Adenomas
Authors: T Iida, Y Kimoto, Y Etsuko, S Banjoya, N Tomita, T Kimura, K Furuta, H Yamazaki, N Takeuchi, Y Kano, K Ono, Y Minato, K Ohata
Journal: Endoscopy (2025)
Endoscopic Ultrasound-guided hepaticogastrostomy versus hepaticogastrostomy with antegrade stenting for malignant biliary obstruction: a multicentre propensity score analysis
Authors: J B Gornals, J Samanta, J R Aparicio Tomo, S Sundaram, B Zurita-Céspedes, J Dhar, B Martínez-Moreno, J Escuer-Turu, A Arrubla-Gamboa, G Shravan, P López-Muñoz, M Puigcerver-Mas, S Fernandez-Herrera, M Akhil, S Homdedeu-Montaña, B Laquente, C Fabregat, J Peñafiel-Muñoz, J Busquets-Barenys, C Loras-Alastruey, J J Vila
Journal: Endoscopy (2025)
Should We Be More Selective with Rectal ESD? Analysis of the Prospective Multicenter Spanish CR-ESD Registry
Authors: A Lanas Gimeno, J C Marín-Gabriel, J Rodríguez Sánchez, A Herreros De Tejada, D de Frutos, J Santiago, H Uchima, E Albéniz, F Ramos Zabala, E Rodriguez de Santiago, P De Maria Pallares, G Fernández-Esparrach, C Guarner Argente, P Rosón Rodriguez, Á Terán, M Fraile-Lopez, A Amoros Tenorio, C Dolz, H Cortes, A Sanchez-Yague, R Duran, D García Romero, A Alvarez, Ó Nogales Rincón, A Del Pozo, J Díaz Tasende
Journal: Endoscopy (2025)
Margin Thermal Ablation Eliminates Size as a Risk factor for Recurrence after Piecemeal Endoscopic Mucosal Resection of Large Non-Pedunculated Colorectal Polyps
Authors: J Gauci, F V Mandarino, C Kerrison, A Whitfield, T O'sullivan, S Gupta, B Lam, V Peranathan, O Cronin, L Bracken, EY T Lee, S Williams, N Burgess, M J Bourke
Journal: Endoscopy (2025)
Volumes and Standards of care in Gastroenterology and Digestive Endoscopy for Biliopancreatic Diseases: from emergency department to discharge
Authors: C Coluccio, W Balzi, C Binda, I Massa, S Fabbri, P Giuffrida, M Sbrancia, I De Felice, T Montella, E De Madaria, G Capurso, C Fabbri
Journal: Endoscopy (2025)
Cholangioscopy-Guided Lithotripsy in Complex Biliary Lithiasis: Fully Covered Metal Stents to Facilitate Extraction
Authors: E Guarner, M Concepción Martin, M Murzi Pulgar, R Romito, I Blanco, S Navajas, V Gomariz, M Camps, V Acin, C Guarner Argente, C Gómez Oliva
Journal: Endoscopy (2025)
Type of submucosal injection solution for endoscopic resection of large colon polyps – results of a randomized trial
Authors: H Pohl, D K Rex, J Barber, M Moyer, J Elmunzer, A Rastogi, S Gordon, E Zolotarevsky, J M Levenick, H Aslanian, M Elatrache, D Von Renteln, M B Wallace, B Brahmbhatt, R Keswani, N Kumta, D K Pleskow, Z Smith, M K Abu Ghanimeh, S Simmer, O Sanaei, Z Yang, T Mackenzie, C Piraka
Journal: Endoscopy (2025)
A selective resection algorithm for large non-pedunculated colorectal polyps (LNPCPs) optimizes outcomes of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD)
Authors: K Khalaf, S Gupta, H Tony, Y Fujiyoshi, N Calo, G May, C Teshima, J Mosko
Journal: Endoscopy (2025)
Intentional selective myotomy of the lower esophageal sphincter and gastric during peroral endoscopic myotomy. PREPOEMSELECT study, preliminary results
Authors: R Muñoz González, E Rojo, C Guarner Argente, M Murzi Pulgar, P De Maria Pallares, P Miranda García, S Parejo, I Marín Fernández, A Calm, J C Balboa, A Pèlach, S Dall'oglio, A Avella, E Rodriguez de Santiago, H Uchima
Journal: Endoscopy (2025)
Novel hemostatic technique for intraoperative bleeding during underwater endoscopic submucosal dissection
Authors: Y Imura, T Akimoto, M Sasaki, Y Kubo, R Mizobe, M Sugawara, M Ishizawa, M Owada, A Katsumi, M Shoma, I Kentaro, A Tojo, K Miyazaki, S Hinako, M Teppei, M Mizutani, M Nishikawa, T Yusaku, S Kawasaki, S Tomohisa, H Tomida, N Matsuura, N Atsushi, K Takabayashi, T Kanai, K Motohiko, N Yahagi
Journal: Endoscopy (2025)
European Consensus Recommendations for direct Cholangioscopy and Pancreatoscopy Using a Modified Delphi Process
Authors: E Palmeri, S Stefanovic, E Gökce, V Ascenti, A Anderloni, V Cennamo, F Prat, G Webster, D Joshi, P Jonathan, T Wong, R Sturgess, K Oppong, J Martin, M Huggett, J Portal, M Ellrichmann, J J Vila, I Fernández-Urién, M Udd, M L Kylänpää, W Laleman, J W Poley, P Karagyozov, F Van Der Heide, J J Koornstra, E Aljahdli, C Gerges, R P Voermans, G Goodchild, A Inderson, P J De Jonge, S F Crinò, M Bruno, D M de Jong, P Hindryckx
Journal: Endoscopy (2025)
Comparison of rebamipide and tegoprazan combination therapy and tegoprazan monotherapy on the healing of endoscopic submucosal dissection-induced gastric ulcer: A randomized-controlled multicenter study
Authors: G H Baik, Y J Yang, H Lim, W G Shin, J G Lee, C K Oh, J J Hyun, Y J Kim, S I Seo
Journal: Endoscopy (2025)
Chatbots and Ethical Medical Practice: An In-Depth Analysis of ChatGPT and Google GEMINI in Gastroenterology
Authors: R M Ram mohan, D Natt, S R Magam, M Joy, L Pannikodu, A Tadikonda, P Achal, W Lau, B Sri Harsha, S Giridharan, Z Amina, P Venkata, P Mustacchia
Journal: Endoscopy (2025)
Endoscopic Ultrasound (EUS)-Guided Gallbladder Drainage vs EUS-Guided Bile Duct Drainage for First Line Therapy of Malignant Biliary Obstruction: An International Multicenter Study
Authors: M Benedetto, D Paduano, D Ramai, G franchellucci, C Barbera, F Frigo, A Fugazza, G De Nucci, G Vanella, C Ko, D M Francesco, A Larghi, A Anderloni, F Auriemma, F Minini, P Arcidiacono, C Gentile, C Federica, L L De, A Y Teoh, C Gallo, E Forti, M Mutignani, M Santi, H Bertani, G Aragona, E Troncone, G Del Vecchio Blanco, KD C Pham, V G Mirante, S F Crinò, E Aljahdli, S Sundaram, A Al-Lehibi, A Alfadda, M Fiacca, G Manes, F Decembrino, G Fierro, G Manes, J D Morris, B Martínez, J R Aparicio, S Stigliano, M Bronswijk, S Van der Merwe, S Lakhtakia, A Ventra, A Repici, A Facciorusso
Journal: Endoscopy (2025)
Comparable long-term efficacy of cold and hot EMR of large colon polyps – follow up results of a randomized trial
Authors: H Pohl, D K Rex, J Barber, A Rastogi, M Moyer, J M Levenick, D Von Renteln, S Gordon, H Aslanian, M Elatrache, M B Wallace, J Elmunzer, R Keswani, N Kumta, D K Pleskow, E Tonzi M, T Mackenzie, C Piraka
Journal: Endoscopy (2025)
REDUCE – Over-the-scope clip-based endoscopic anastomotic reduction in patients with dumping-syndrome after gastric bypass
Authors: A Kuellmer, M Kandler, S Nagl, K Laubner, J Mueller, M Meyer-Steenbuck, R Kaeser, L Sturm, J Seufert, R Thimme, A Schmidt
Journal: Endoscopy (2025)
Safety and feasibility of Outpatient Full-Thickness resection for colorectal lesions: The SOFT study
Authors: M Gagliardi, C Abbatiello, G Grande, G De Nucci, G Gibiino, C Binda, F Pugliese, M Stegagnini, M C Campanale, L Pignata, G L Papparella, A Anderloni, S Agazzi, L Rovedatti, S Sferrazza, G Leonardi, S Camera, C Soldaini, M Fusco, S Rizza, A Iannone, A Di Leo, T Staiano, R Di Mitri, R Manta, G Costamagna, R Conigliaro, G Manes, C Fabbri, M Mutignani, A Maurano, M Sica, C Zulli
Journal: Endoscopy (2025)
Impact of ESD Case Volume per Year on Rectal Lesions: Analysis of the Prospective Multicenter Spanish CR-ESD Registry
Authors: A Lanas Gimeno, J C Marín-Gabriel, J Rodríguez Sánchez, A Herreros De Tejada, J Santiago, D de Frutos, H Uchima, E Albéniz, F Ramos Zabala, E Rodriguez de Santiago, P Rosón Rodriguez, P De Maria Pallares, C Guarner Argente, G Fernández-Esparrach, A Amoros Tenorio, A Alvarez, A Sanchez-Yague, H Cortes, Ó Nogales Rincón, Á Terán, R Duran, M Fraile-Lopez, D García Romero, C Dolz, A Del Pozo, J Díaz Tasende
Journal: Endoscopy (2025)
The « DEBE » score predicts the risk of delayed bleeding after colorectal endoscopic dissection in a large European multicenter cohort
Authors: E Albéniz, M Pioche, J C Marin-Gabriel, A Herreros-De-Tejada, T Wallenhorst, R Jerome, L Romain, T Degand, M Schaefer, J B Chevaux, F Ramos Zabala, Y Le Baleur, F Rostain, A Berger, P Rosón Rodriguez, Á Terán, A Lupu, J Santiago Garcia, E Chabrun, H Lepetit, B Brieau, B Maximilien, H Uchima, F Gallego Rojo, J De La Peña, A Jeremie, P Bonniaud, S Chaussade, J Rodríguez Sánchez, A Amoros Tenorio, A Belle, M Dahan, D García Romero, P Leclercq, E Rodriguez de Santiago, S Parejo, O Nogales, O Plomteux, J B Zeevaert, G Fernández-Esparrach, A Sanchez-Yague, U Goikoetxea, T Grainville, F Estremera-Arevalo, M Gómez Alonso, M Enguita, S Montori, J Jacques
Journal: Endoscopy (2025)
Endoscopic resection of gastric lesions in familial adenomatous polyposis: a prospective international cohort study
Authors: H Bouchiba, A S Aelvoet, J Gásdal Karstensen, F Balaguer, M Daca-Alvarez, M E Van Leerdam, PM M Bossuyt, AM J Langers, M Pellise, BA J Bastiaansen, E Dekker
Journal: Endoscopy (2025)
VACStent For The Treatment Of Upper Gastrointestinal Tract Leaks And Defects: Results From Prospective Series In A Tertiary Referral Center
Authors: F V Mandarino, G Dell'Anna, F Bernardi, E Fasulo, A Barchi, L Fanti, F Azzolini, E Vespa, S Battaglia, L Barbieri, L Fuccio, U Elmore, R Rosati, S Danese
Journal: Endoscopy (2025)
Evaluation of an improved computer aided detection system for Barrett’s neoplasia on real world imaging conditions
Authors: R van Eijck van Heslinga, M Jong, K Kusters, T Jaspers, T Boers, J Van Der Putten, L Duits, R Pouw, B Weusten, M Houben, A Alkhalaf, F Van Der Sommen, P De With, J De Groof, J Bergman
Journal: Endoscopy (2025)
Real-life prospective evaluation of a novel computer-aided detection (CAD) of Barrett’s neoplasia: Do we still need quadrantic biopsies following CAD targeted biopsies?
Authors: H Htet, K Siggens, S Subramaniam, H Suthan, M White, E Mastrorocco, A Joyce, F Chedgy, K Kandiah, P Bhandari
Journal: Endoscopy (2025)
Endoscopic Vacuum Therapy (EVT) for the Management of Upper Gastrointestinal Tract Leaks and Defects: A Retrospective Study from a Tertiary Referral Center in Nearly 100 Patients
Authors: F V Mandarino, G Dell'Anna, F Bernardi, E Fasulo, R Bara, A Barchi, L Fanti, F Azzolini, S Battaglia, L Barbieri, E Vespa, L Fuccio, U Elmore, R Rosati, S Danese
Journal: Endoscopy (2025)
Irish capsule endoscopy registry (ICaRe) data indicates that the diagnostic yield for significant small bowel lesions is similar in patients irrespective of bowel preparation with purgatives
Authors: D Kripakaran, C Costigan, B Hall, E Gibbons, V Parihar, M Ferry, K Van Der Merwe, C Goulding, C Walker, M Hussey, G Holleran, I Osmerova, D McNamara
Journal: Endoscopy (2025)
Do we need to re-evaluate the role of fine-needle aspiration in infected necrotizing pancreatitis in the post-POINTER era?
Authors: H S Pauw, A Beij, H C Timmerhuis, L Boxhoorn, M G Besselink, M A Boermeester, M J Bruno, ACIT L Tan, P Duijvendijk, T Romkens, M Hadithi, M P Schwartz, N G Venneman, J M Jansen, MW J Stommel, R Quispel, B J Witteman, W Curvers, T Seerden, W L Hazen, S A Bouwense, MB W Spanier, J W Haveman, R C Verdonk, E Sieswerda, R P Voermans, H C Van Santvoort, F F Van Den Berg
Journal: Endoscopy (2025)
Deep Learning and Automatic Capsule Endoscopy Segmentation – A Crucial Step Towards AI-assisted Capsule Panendoscopy
Authors: F Mendes, M Mascarenhas, J Afonso, M Martins, P Marílio Cardoso, M J Almeida, J Mota, P Andrade, H Cardoso, J Fernandes, J Ferreira, M Mascarenhas Saraiva, M Guilherme
Journal: Endoscopy (2025)
Learning curve assessment of EUS-guided gastroenterostomy for inexperienced centers by supervised-training: A Multicenter prospective study (GESICA project)
Authors: D Luna-Rodriguez, C Loras, S Bazaga, J Colan-Hernandez, H Carlos, C Guarner-Argente, L Barranco Priego, C Claudia, M González-Haba Ruiz, M Rodriguez-Tellez, P Ruiz-Ramirez, F Bas-Cutrina, E Nuñez, S Maisterra, M Hombrados, M Murzi Pulgar, B Agudo, S G Albert, I Salvador, B Laquente, M Calvo, A Lagarda, J B Gornals
Journal: Endoscopy (2025)
Regenerative Endoscopy for the treatment of difficult gastrointestinal defects
Authors: V Pontecorvi, D Nachira, S Margaritora, A Trivisonno, M Papi, M V Matteo, B Vincenzo, M De Siena, L Gualtieri, A A Caretto, S Gentileschi, F Fanfani, G Scambia, C Spada, I Boskoski
Journal: Endoscopy (2025)
Long-term results of a prospective study comparing lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotizing pancreatitis
Authors: A Beij, L Boxhoorn, A M Onnekink, R C Verdonk, M G Besselink, T L Bollen, S A Bouwense, M Kop, V C Cappendijk, W Curvers, H Van Dullemen, C H Van Eijck, M Hadithi, W L Hazen, P Honkoop, J E Van Hooft, E Kouw, S D Kuiken, M Ledeboer, V B Nieuwenhuijs, L Perk, J W Poley, R Quispel, RJ J De Ridder, H C Van Santvoort, MW J Stommel, B J Witteman, N G Venneman, F P Vleggaar, R L van Wanrooij, M J Bruno, P Fockens, R P Voermans
Journal: Endoscopy (2025)
DNA and RNA extraction for molecular analyses from EUS-acquired pancreatic neoplasia samples employing different needles: a cohort of more than 300 cases
Authors: L Archibugi, R Ponz de Leon Pisani, M Tacelli, E Liberanome, P Biamonte, G Lauri, C Fortunato, L De Carolis, P Zaccari, G Rossi, M C Petrone, G Vanella, F Frigo, I Marengon, L Apadula, C Stornello, N Bina, R Nunziata, D Bellafante, P Arcidiacono, G Capurso
Journal: Endoscopy (2025)
Split-dose oral lactulose vs split-dose high-volume polyethylene glycol as a bowel preparation in outpatient colonoscopies (LACPEG): a single-blind, randomized, single-center, clinical trial
Authors: E Jasso Baltazar, R Macias-Rodriguez, G Rosales Sotomayor, L C Chavez, V A Venegas-Gomez, A Fernández Ramírez, F Valdovinos Andraca, Á Saúl Pérez
Journal: Endoscopy (2025)
Differentiation of MD-IPMN from Chronic Pancreatitis by cfDNA Next Generation Sequencing from Ductal Fluid Using EUS-Guided FNA: A Prospective Controlled Study
Authors: D Schmitz, S Prax, M Kliment, D Kazdal, M Allgäuer, P Schirmacher, A Stenzinger, J P Ritz, A L Volckmar
Journal: Endoscopy (2025)
Three-year oncological outcomes of endoscopic full-thickness resection for scar excision after incomplete resection of low-risk T1 colorectal cancer: results from the Dutch nationwide prospective eFTR registry
Authors: S C Albers, L W Zwager, F Bekkering, J J Boonstra, F Ter Borg, P Fockens, E Gielisse, MHM G Houben, R Ten Hove, W B Nagengast, L Perk, D Ramsoekh, F Rando Munoz, R M Schreuder, M P Schwartz, H Van Der Sluis, B Van Der Spek, J S Terhaar Sive Droste, M Vlug, B Weusten, C Wientjes, T R De Wijkerslooth, A Farina Sarasqueta, E Dekker, BA J Bastiaansen
Journal: Endoscopy (2025)
DNA-based delivery of G-CSF as a durable and efficacious approach to treat severe chronic neutropenia
Authors: Marek M. Drozdz, Andy T. Thompson, Linda Sasset, Andrew D. Cameron, Xin Yao, Debnath Maji, Delcora A. Campbell, Carleigh Sussman, Robert Miller, Rachel A. Liberatore
Journal: Molecular Therapy (2025)
Computational fluid dynamics model predictions of inhaled corticosteroid deposition in patients with severe asthma
Authors: Nandhitha Ragunayakam, Ashutosh Thakar, Hosein Sadafi, Carmen Venegas Garrido, Yonni Friedlander, Melanie Kjarsgaard, Kayla Zhang, Anna Dvorkin-Gheva, Manali Mukherjee, Myrna B Dolovich, Ben R Lavon, Mark Inman, Parameswaran Nair, Sarah Svenningsen
Journal: Thorax (2025)

Background Some patients with severe asthma have persistent type-2 inflammation despite being treated with high-dose inhaled corticosteroids (ICS). The variability in ICS deposition between patients with severe asthma is not well-understood and could contribute to this persistence. Objectives To characterise and compare model-predicted deposition of fine-particle and extrafine-particle ICS in patients with severe asthma based on biomarkers of type-2 inflammation, airway morphology and airway function. Methods Twenty-eight patients with severe asthma performed full-inspiration and full-expiration chest CT on the same day that biomarkers of type-2 inflammation were measured. Functional respiratory imaging and computational fluid dynamics were used to simulate and predict intrathoracic, central and peripheral airway deposition, and central-to-peripheral airway deposition (C:P) ratio of fine-particle ICS (fluticasone-propionate HFA) (ICS FP ) and extrafine-particle ICS (beclomethasone-dipropionate HFA) (ICS EFP ). CT-derived wall area percent (WA%), lumen area (LA) and mucus burden were quantified to characterise airway morphology. Results Simulated deposition of ICS EFP was higher than ICS FP in the intrathoracic, central and peripheral airways (all p&lt;0.0001). Greater WA% and smaller LA were correlated with greater C:P ratio of ICS FP (r=0.60, p=0.0068; r=−0.60, p=0.0072) and ICS EFP (r=0.54, p=0.028; r=−0.54, p=0.026). Participants with elevated sputum eosinophils had a greater C:P ratio, irrespective of particle size (ICS FP , p=0.045; ICS EFP , p=0.021). Conclusions In severe asthma patients with thicker airway walls, narrower airway lumens and elevated biomarkers of type-2 inflammation, a smaller ratio of ICS FP reached the peripheral airways. ICS EFP did not fully mitigate this. Patient-specific airway morphology may impact regional ICS deposition and contribute to persistent inflammation.