tbuckley/cabot-search huggingface dataset:
Variable Tracer Avidity and Interlesional Heterogeneity on 18F-FDG, 68Ga-DOTATATE, and 68Ga-DOTA-FAPi-04 PET/CT Imaging in a Single Individual Patient With Progressive Metastatic Medullary Thyroid Carcinoma
Authors: Yeshwanth Edamadaka, Rahul V. Parghane, Sandip Basu
Journal: Clinical Nuclear Medicine (2024)

Abstract In medullary thyroid carcinoma (MTC), distant metastases have few therapeutic options with low success rates and substantial toxicity in many patients, warranting exploration of alternate systemic treatments with fewer adverse effects. The fibroblast activation protein inhibitor (FAPI)–based PET/CT opens new avenues for several cancers, including MTC. A case of MTC with varying tracer avidity and interlesional heterogeneity on 18 F-FDG, 68 Ga-DOTATATE, and 68 Ga-DOTA-FAPI-04 PET/CT imaging is presented. 68 Ga-DOTA-FAPI-04 PET/CT exhibited superior efficacy in terms of visualization of metastatic soft tissue, lymph nodal, and skeletal lesions, with enhanced target-to-background ratio compared with the other two, facilitating the detection of these lesions, thereby demonstrating the potential for theranostic translation.
Retrospective Data-Driven Motion Correction of 18F-FDG Brain PET
Authors: Alexander Maurer, Matthew G. Spangler-Bickell, Cäcilia E. Mader, Fotis Kotasidis, Martin W. Huellner
Journal: Clinical Nuclear Medicine (2024)

A 51-year-old man with severe multifactorial neurocognitive disorders subsequent to delirium, benzodiazepine withdrawal, and preexisting psychiatric illness was referred for 18 F-FDG PET/CT brain imaging in order to rule out an underlying neurodegenerative cause of the symptoms, particularly frontotemporal lobar degeneration. Imaging was impaired by severe motion artifacts, leading to a false-positive result. However, utilizing retrospective data-driven motion correction facilitated a change in diagnosis, ruling out the presence of neurodegenerative disease. The implementation of motion correction of the 18 F-FDG PET dataset proved crucial for the patient, as the exclusion of frontotemporal lobar degeneration formed the basis for continuing psychiatric and psychotherapeutic treatment.
Author Correction: Digital consults in heart failure care: a randomized controlled trial
Authors: Jelle P Man, Maarten A C Koole, Paola G Meregalli, M Louis Handoko, Susan Stienen, Frederik J de Lange, Michiel M Winter, Marlies P Schijven, Wouter E M Kok, Dorianne I Kuipers, Pim van der Harst, Folkert W Asselbergs, Aeilko H Zwinderman, Marcel G W Dijkgraaf, Steven A J Chamuleau, Mark J Schuuring
Journal: Nature Medicine (2024)
Increased TSPO, COX-1, and COX-2 Uptake in Bone Marrow Within a Falx Cerebri Ossification
Authors: Xuefeng Yan, Fabrice G Siméon, Victor W Pike, Robert B Innis, Paolo Zanotti-Fregonara
Journal: Clinical Nuclear Medicine (2024)

Abstract Ossification is uncommon, generally asymptomatic, and often incidentally identified in imaging studies. We report on a 54-year-old man who participated as a healthy volunteer in a clinical trial using PET imaging to investigate neuroinflammation. An incidental ossified lesion in the anterior falx cerebri was revealed by MRI. CT scan showed a small hypodense center in the lesion, probably corresponding to bone marrow. The PET scans using 18 F-SF51, 11 C-PS13, and 11 C-MC1 showed increased uptake within this lesion, which was probably related to bone marrow activity within the ossification.
Noninvasive, microbiome-based diagnosis of inflammatory bowel disease
Authors: Jiaying Zheng, Qianru Sun, Mengjing Zhang, Chengyu Liu, Qi Su, Lin Zhang, Zhilu Xu, Wenqi Lu, Jessica Ching, Whitney Tang, Chun Pan Cheung, Amy L Hamilton, Amy L Wilson O'Brien, Shu Chen Wei, Charles N Bernstein, David T Rubin, Eugene B Chang, Mark Morrison, Michael A Kamm, Francis K L Chan, Jingwan Zhang, Siew C Ng
Journal: Nature Medicine (2024)
Profibrotic monocyte-derived alveolar macrophages are expanded in patients with persistent respiratory symptoms and radiographic abnormalities after COVID-19
Authors: Joseph I Bailey, Connor H Puritz, Karolina J Senkow, Nikolay S Markov, Estefani Diaz, Emmy Jonasson, Zhan Yu, Suchitra Swaminathan, Ziyan Lu, Samuel Fenske, Rogan A Grant, Hiam Abdala-Valencia, Ruben J Mylvaganam, Amy Ludwig, Janet Miller, R Ian Cumming, Robert M Tighe, Kymberly M Gowdy, Ravi Kalhan, Manu Jain, Ankit Bharat, Chitaru Kurihara, Ruben San Jose Estepar, Raul San Jose Estepar, George R Washko, Ali Shilatifard, Jacob I Sznajder, Karen M Ridge, G R Scott Budinger, Rosemary Braun, Alexander V Misharin, Marc A Sala
Journal: Nature Immunology (2024)
Underrepresented minority faculty in the USA face a double standard in promotion and tenure decisions
Authors: Theodore Masters-Waage, Christiane Spitzmueller, Ebenezer Edema-Sillo, Ally St Aubin, Michelle Penn-Marshall, Erika Henderson, Peggy Lindner, Cynthia Werner, Tracey Rizzuto, Juan Madera
Journal: Nature Human Behaviour (2024)
Multiomic profiling identifies predictors of survival in African American patients with acute myeloid leukemia
Authors: Andrew Stiff, Maarten Fornerod, Bailee N Kain, Deedra Nicolet, Benjamin J Kelly, Katherine E Miller, Krzysztof Mrózek, Isaiah Boateng, Audrey Bollas, Elizabeth A R Garfinkle, Omolegho Momoh, Foluke A Fasola, Hannah O Olawumi, Nuria Mencia-Trinchant, Jean F Kloppers, Anne-Cecilia van Marle, Eileen Hu, Saranga Wijeratne, Gregory Wheeler, Christopher J Walker, Jill Buss, Adrienne Heyrosa, Helee Desai, Andrea Laganson, Ethan Hamp, Yazan Abu-Shihab, Hasan Abaza, Parker Kronen, Sidharth Sen, Megan E Johnstone, Kate Quinn, Ben Wronowski, Erin Hertlein, Linde A Miles, Alice S Mims, Christopher C Oakes, James S Blachly, Karilyn T Larkin, Bethany Mundy-Bosse, Andrew J Carroll, Bayard L Powell, Jonathan E Kolitz, Richard M Stone, Cassandra Duarte, Diana Abbott, Maria L Amaya, Craig T Jordan, Geoffrey L Uy, Wendy Stock, Kellie J Archer, Electra D Paskett, Monica L Guzman, Ross L Levine, Kamal Menghrajani, Debyani Chakravarty, Michael F Berger, Daniel Bottomly, Shannon K McWeeney, Jeffrey W Tyner, John C Byrd, Nathan Salomonis, H Leighton Grimes, Elaine R Mardis, Ann-Kathrin Eisfeld
Journal: Nature Genetics (2024)
Immunometabolic cues recompose and reprogram the microenvironment around implanted biomaterials
Authors: Chima V Maduka, Axel D Schmitter-Sánchez, Ashley V Makela, Evran Ural, Katlin B Stivers, Hunter Pope, Maxwell M Kuhnert, Oluwatosin M Habeeb, Anthony Tundo, Mohammed Alhaj, Artem Kiselev, Shoue Chen, Alexis Donneys, Wade P Winton, Jenelle Stauff, Peter J H Scott, Andrew J Olive, Kurt D Hankenson, Ramani Narayan, Sangbum Park, Jennifer H Elisseeff, Christopher H Contag
Journal: Nature Biomedical Engineering (2024)
Diuretic dosing and outcomes with torsemide and furosemide following hospitalization for heart failure: The <scp>TRANSFORM</scp>‐<scp>HF</scp> trial
Authors: Nina Nouhravesh, Stephen J. Greene, Robert Clare, Daniel Wojdyla, Kevin J. Anstrom, Eric Velazquez, Bertram Pitt, Robert J. Mentz, Mitchell A. Psotka
Journal: European Journal of Heart Failure (2024)
Targeted Therapy of Osteoarthritis via Intra‐Articular Delivery of Lipid‐Nanoparticle‐Encapsulated Recombinant Human FGF18 mRNA
Authors: Mengze Sun, Bin Ma, Zihang Pan, Yun Zhao, Liangliang Tian, Yifei Fan, Weijing Kong, Junyan Wang, Boyang Xu, Yingfang Ao, Quanyi Guo, Xi Wang, Xiaohong Peng, Xiaoxia Li, Jin Cheng, Lei Miao, Kai Wang, Xiaoqing Hu
Journal: Advanced Healthcare Materials (2024)

Abstract Fibroblast growth factor 18 (FGF18) emerges as a promising therapeutic target for osteoarthritis (OA). In this study, a novel articular cavity‐localized lipid nanoparticle (LNP) named WG‐PL14 is developed. This optimized formulation has a nearly 30‐fold increase in mRNA expression as well as better articular cavity enrichment compared to commercial lipids MC3 when performing intra‐articular injection. Then, a mRNA sequence encoding recombinant human FGF18 (rhFGF18) for potential mRNA therapy in OA is optimized. In vitro assays confirm the translation of rhFGF18 mRNA into functional proteins within rat and human chondrocytes, promoting cell proliferation and extracellular matrix (ECM) synthesis. Subsequently, the therapeutic efficacy of the LNP‐rhFGF18 mRNA complex is systematically assessed in a mouse OA model. The administration exhibits several positive outcomes, including an improved pain response, upregulation of ECM‐related genes (e.g., AGRN and HAS2), and remodeling of subchondral bone homeostasis compared to a control group. Taken together, these findings underscore the potential of localized LNP‐rhFGF18 mRNA therapy in promoting the regeneration of cartilage tissue and mitigating the progression of OA.
Neuroendocrine transdifferentiation in human cancer: molecular mechanisms and therapeutic targets
Authors: Jun Jiang, Donghui Han, Jiawei Wang, Weihong Wen, Rui Zhang, Weijun Qin
Journal: MedComm (2024)

Abstract Neuroendocrine transdifferentiation (NEtD), also commonly referred to as lineage plasticity, emerges as an acquired resistance mechanism to molecular targeted therapies in multiple cancer types, predominately occurs in metastatic epidermal growth factor receptor (EGFR)‐mutant non‐small cell lung cancer treated with EGFR tyrosine kinase inhibitors and metastatic castration‐resistant prostate cancer treated with androgen receptor targeting therapies. NEtD tumors are the lethal cancer histologic subtype with unfavorable prognosis and limited treatment. A comprehensive understanding of molecular mechanism underlying targeted‐induced plasticity could greatly facilitate the development of novel therapies. In the past few years, increasingly elegant studies indicated that NEtD tumors share key the convergent genomic and phenotypic characteristics irrespective of their site of origin, but also embrace distinct change and function of molecular mechanisms. In this review, we provide a comprehensive overview of the current understanding of molecular mechanism in regulating the NEtD, including genetic alterations, DNA methylation, histone modifications, dysregulated noncoding RNA, lineage‐specific transcription factors regulation, and other proteomic alterations. We also provide the current management of targeted therapies in clinical and preclinical practice.
Pseudo‐3D Topological Alignments Regulate Mechanotransduction and Maturation of Smooth Muscle Cells
Authors: Yeji Lee, Jihyeon Song, Ulziituya Batjargal, Min‐Seok Kim, Geonho Lee, Geonwoo Kim, Taehoon Lee, RaeHui Kang, Younggyun Kim, Han‐Jun Kim, Junmin Lee
Journal: Advanced Healthcare Materials (2024)

Abstract Smooth muscle cells (SMCs) sense and respond to mechanical stimuli in their extracellular microenvironments (ECMs), playing a crucial role in muscle tissue engineering. Increasing evidence from topological cues‐mediated mechanotransduction of SMCs in ECMs has suggested some potential underlying mechanisms of how SMC functions and maturation are regulated by their mechanosensing leading to transduction. However, how the expression of yes‐associated protein 1 (YAP) influences the phenotypic shift from synthetic to contractile is still controversial. Here, pseudo‐3D topological alignments mimicking native muscle tissues are generated using laser‐cutter engraving to explore the influence of topological cues on SMC mechanotransduction and maturation. The analysis of topological cue‐mediated mechanotransduction and maturation marker expression revealed YAP is involved in mechanotransduction for SMCs cultured on cross‐patterned substrates in the presence of cell‐cell interactions. Moreover, these SMCs with YAP‐linked mechanosensing showed higher expression of calponin, indicating a shift toward contractile phenotypes in vitro and in vivo. Furthermore, it showed skeletal muscle cells has different mechanosensing and maturation mechanisms compared to SMCs, revealing muscle type‐dependent different sensing of topological cues, and converting into maturation‐associated signaling cascades. This study provides insights into the regulation of SMC mechanotransduction and maturation by topological cues, suggesting the involvement of YAP‐linked signaling pathways in this process.
A New Era of Data-Driven Cancer Research and Care: Opportunities and Challenges
Authors: Felicia Gomez, Arpad M. Danos, Guilherme Del Fiol, Anant Madabhushi, Pallavi Tiwari, Joshua F. McMichael, Spyridon Bakas, Jiang Bian, Christos Davatzikos, Elana J. Fertig, Jayashree Kalpathy-Cramer, Johanna Kenney, Guergana K. Savova, Meliha Yetisgen, Eliezer M. Van Allen, Jeremy L. Warner, Fred Prior, Malachi Griffith, Obi L. Griffith
Journal: Cancer Discovery (2024)

Summary: People diagnosed with cancer and their formal and informal caregivers are increasingly faced with a deluge of complex information, thanks to rapid advancements in the type and volume of diagnostic, prognostic, and treatment data. This commentary discusses the opportunities and challenges that the society faces as we integrate large volumes of data into regular cancer care.
Being Smarter, Azobenzene‐Containing Biomaterial Showing Triple Stimuli‐Responsive Phase Change Property to Light, Humidity and Force at Room Temperature
Authors: Lei Zhang, Qianyao Du, Ziying Zhang, Jia Chen, Yun Liu, Xiliang Luo, Zhen Wang, Zhongtao Wu
Journal: Advanced Healthcare Materials (2024)

Abstract Multiple stimuli‐responsiveness is an attractive property that is studied in physical chemistry and materials chemistry. While, multiple stimuli‐responsive phase change in an isothermal way is rarely addressed for functional materials at room temperature. In this study, one azobenzene‐containing surfactant AZO is designed for the fabrication of triple stimuli‐responsive phase change biomaterial (Alg‐AZO) through the electrostatic complexation with natural alginate. Thanks to the photoisomerization ability, molecular flexibility and hydrophilicity of AZO, together with the tailoring effect of alginate on AZO, Alg‐AZO could perform reversible isothermal phase transition between liquid crystalline and isotropic liquid states under the stimuli of either light or humidity at room temperature. Furthermore, the humidity‐induced isotropic state can also fast transit to ordered state under shear force, owing to the π‐π interactions between planar trans‐ AZO in Alg‐AZO material. With good biocompatibility, self‐healing property and in vivo wound healing promoting capacity that is promoted by light, humidity and force, Alg‐AZO would be suitable for working as a new smart biomaterial in biological and biomedical areas. This work provides a designing strategy for gaining multiple stimuli‐responsive smart materials based on biomacromolecules, and also opening a new opportunity for gaining self‐healing biomaterials capable of working in various conditions.
Lymphatic‐specific methyltransferase‐like 3‐mediated m<sup>6</sup>A modification drives vascular patterning through prostaglandin metabolism reprogramming
Authors: Lianjun Shi, Shuting Lu, Xue Han, Fan Ye, Xiumiao Li, Ziran Zhang, Qin Jiang, Biao Yan
Journal: MedComm (2024)

Abstract Lymphangiogenesis plays a pivotal role in the pathogenesis of various vascular disorders, including ocular vascular diseases and cancers. Deregulation of N 6 ‐methyladenosine (m 6 A) modification has been identified as a key contributor to human diseases. However, the specific involvement of m 6 A modification in lymphatic remodeling remains poorly understood. In this study, we demonstrate that inflammatory stimulation and corneal sutures induce elevated levels of methyltransferase‐like 3 (METTL3)‐mediated m 6 A modification. METTL3 knockdown inhibits lymphatic endothelial viability, proliferation, migration, and tube formation in vitro. METTL3 knockdown attenuates corneal sutures‐induced lymphangiogenesis and intratumoral lymphangiogenesis initiated by subcutaneous grafts, consequently restraining corneal neovascularization, tumor growth, and tumor neovascularization in vivo. Mechanistically, METTL3 knockdown upregulates prostaglandin–endoperoxide synthase 2 expression through an m 6 A–YTHDF2‐dependent pathway, enhancing the synthesis of cyclopentenone prostaglandins (CyPGs). Aberrant CyPG production in lymphatic endothelial cells impairs mitochondrial oxidative phosphorylation, contributing to pathological lymphangiogenesis. Moreover, selective inhibition of METTL3 with STM2457 reduces m 6 A levels in lymphatic endothelial cells, effectively suppressing pathological lymphangiogenesis. This study provides compelling evidence that lymphatic‐specific METTL3 plays a critical role in vascular patterning through prostaglandin metabolism reprogramming. Thus, METTL3 emerges as a promising target for treating lymphangiogenesis‐related diseases.
Oligonucleotide‐Linked Lipid Nanoparticles as a Versatile mRNA Nanovaccine Platform
Authors: San Hae Im, Youseung Chung, Nevena Duskunovic, Heewon Choi, Su‐Hyung Park, Hyun Jung Chung
Journal: Advanced Healthcare Materials (2024)

Abstract An effective delivery platform is crucial for the development of mRNA vaccines and therapeutics. Here, a versatile platform utilizing cholesterol‐modified oligonucleotides (L‐oligo) that bind to the mRNA within lipid nanoparticles (LNP), and enables the effective delivery of the mRNA into target cells is introduced. mRNA incorporated into LNPs via linkage with L‐oligo, termed oligonucleotide‐linked LNP (lnLNP), is superior in cellular uptake and transfection efficiency in target cells in vitro and in vivo, compared to the conventional LNP formulations. It is further applied lnLNP as an mRNA vaccine platform for SARS‐CoV‐2, demonstrating robust induction of neutralizing activity as well as polyfunctional SARS‐CoV‐2‐specific T‐cell response in vivo. The current strategy can be versatilely applied to different LNP platforms, for vaccine and therapeutic applications against various diseases, such as infections and cancers.
Long-Term Survival Outcomes With First-Line Nivolumab Plus Ipilimumab–Based Treatment in Patients With Metastatic Non-Small Cell Lung Cancer and Tumor PD-L1 &lt;1%: a Pooled Analysis
Authors: Solange Peters, Luis G Paz-Ares, Martin Reck, David P Carbone, Julie R Brahmer, Hossein Borghaei, Shun Lu, Kenneth J O'Byrne, Thomas John, Tudor-Eliade Ciuleanu, Michael Schenker, Reyes Bernabe Caro, Makoto Nishio, Manuel Cobo, Jong-Seok Lee, Bogdan Zurawski, Adam Pluzanski, Takekazu Aoyama, Marina Tschaika, Vipul Devas, Diederik J Grootendorst, Suresh S Ramalingam
Journal: Journal of Thoracic Oncology (2024)
Engineering Memory T Cells as a platform for Long-Term Enzyme Replacement Therapy in Lysosomal Storage Disorders
Authors: Evan W Kleinboehl, Kanut Laoharawee, Jacob D Jensen, Joseph J Peterson, Nicholas J Slipek, Bryce J Wick, Matthew J Johnson, Beau R Webber, Branden S Moriarity
Journal: Molecular Therapy (2024)
The Epigenetic Hallmarks of Cancer
Authors: Manel Esteller, Mark A. Dawson, Cigall Kadoch, Feyruz V. Rassool, Peter A. Jones, Stephen B. Baylin
Journal: Cancer Discovery (2024)

Abstract Cancer is a complex disease in which several molecular and cellular pathways converge to foster the tumoral phenotype. Notably, in the latest iteration of the cancer hallmarks, “nonmutational epigenetic reprogramming” was newly added. However, epigenetics, much like genetics, is a broad scientific area that deserves further attention due to its multiple roles in cancer initiation, progression, and adaptive nature. Herein, we present a detailed examination of the epigenetic hallmarks affected in human cancer, elucidating the pathways and genes involved, and dissecting the disrupted landscapes for DNA methylation, histone modifications, and chromatin architecture that define the disease. Significance: Cancer is a disease characterized by constant evolution, spanning from its initial premalignant stages to the advanced invasive and disseminated stages. It is a pathology that is able to adapt and survive amidst hostile cellular microenvironments and diverse treatments implemented by medical professionals. The more fixed setup of the genetic structure cannot fully provide transformed cells with the tools to survive but the rapid and plastic nature of epigenetic changes is ready for the task. This review summarizes the epigenetic hallmarks that define the ecological success of cancer cells in our bodies.
Biomimetic Single‐Atom Nanozyme for Dual Starvation‐Enhanced Breast Cancer Immunotherapy
Authors: Ni Zhang, Wei Ping, Jingfeng Xiang, Sitong Chu, Dan Li, Shipeng Ning, Daoming Zhu, Wen Zeng, Qingyong Xu
Journal: Advanced Healthcare Materials (2024)

Abstract Cold exposure (CE) therapy is an innovative and cost‐efficient cancer treatment that activates brown adipose tissue to compete for glucose uptake, leading to metabolic starvation in tumors. Exploring the combined antitumor mechanisms of CE and traditional therapies (such as nanocatalysis) is exciting and promising. In this study, a platelet membrane biomimetic single‐atom nanozyme (SAEs) nanodrug (PFB) carrying bis‐2‐(5–phenylacetamido‐1, 2, 4‐thiadiazol‐2‐yl) ethyl sulfide (BPTES) is developed for use in cancer CE therapy. Owing to the platelet membrane modification, PFB can effectively target tumors. Upon entering cancer cells, the dual starvation effect induced by CE treatment and BPTES can significantly diminish intracellular glucose and ATP levels, resulting in a substantial reduction in cellular (glutathione) GSH, which can enhance the cytotoxic efficacy of reactive oxygen species generated by SAEs. This strategy not only boosts ROS production in tumors, but also strengthens immune responses, particularly by increasing memory T‐cell abundance and suppressing distant tumor growth and tumor metastasis. Compared with SAEs therapy alone, this combined approach offers superior benefits for tumor immunotherapy. This study achieves a combination of CE and nanomedicines for the first time, providing new ideas for future nanomedicine combination therapy modalities.
Monitoring clonal burden as an alternative to blast count for myelodysplastic neoplasm treatment response
Authors: Meagan A Jacoby, Eric D Duncavage, Ajay Khanna, Gue Su Chang, Sridhar Nonavinkere Srivatsan, Christopher A Miller, Feng Gao, Josh Robinson, Jin Shao, Robert S Fulton, Catrina C Fronick, Michelle O'Laughlin, Sharon E Heath, Kimberly Brendel, Monique Chavez, John F DiPersio, Camille N Abboud, Keith Stockerl-Goldstein, Peter Westervelt, Amanda Cashen, Iskra Pusic, Stephen T Oh, John S Welch, Denise A Wells, Michael R Loken, Geoffrey L Uy, Matthew J Walter
Journal: Leukemia (2024)
De novo GTP synthesis is a metabolic vulnerability for the interception of brain metastases
Authors: Agata M Kieliszek, Daniel Mobilio, Blessing I Bassey-Archibong, Jarrod W Johnson, Mathew L Piotrowski, Elvin D de Araujo, Abootaleb Sedighi, Nikoo Aghaei, Laura Escudero, Patrick Ang, William D Gwynne, Cunjie Zhang, Andrew Quaile, Dillon McKenna, Minomi Subapanditha, Tomas Tokar, Muhammad Vaseem Shaikh, Kui Zhai, Shawn C Chafe, Patrick T Gunning, J Rafael Montenegro-Burke, Chitra Venugopal, Jakob Magolan, Sheila K Singh
Journal: Cell Reports Medicine (2024)
Bone-protective effects of neutralizing angiopoietin-like protein 4 monoclonal antibody in rheumatoid arthritis
Authors: Liqing Ke, Qifei He, Jing Qu, Xiyue Wang, Kaibo Li, Xun Gong, Lan Li, Jiake Xu, Qiuliyang Yu, Hao Yu, Xuefei Lin, Jian Li, Nguan Soon Tan, Wei Sun, Liang Li, Peng Zhang, Wenxiang Cheng
Journal: Molecular Therapy (2024)
CIEC: Cross-tissue Immune Cell Type Enrichment and Expression Map Visualization for Cancer
Authors: Jinhua He, Haitao Luo, Wei Wang, Dechao Bu, Zhengkai Zou, Haolin Wang, Hongzhen Tang, Zeping Han, Wenfeng Luo, Jian Shen, Fangmei Xie, Yi Zhao, Zhiming Xiang
Journal: Genomics Proteomics & Bioinformatics (2024)