A DISCUSSION OF THYROID PARAMETERS
Authors: Richard P. Spencer, E. Richard King, Charles R. Henkelmann, Theodore G. Balbus
Journal: Annals of Internal Medicine (1958)

Article1 May 1958A DISCUSSION OF THYROID PARAMETERSRICHARD P. SPENCER, E. RICHARD KING, CHARLES R. HENKELMANN, THEODORE G. BALBUSRICHARD P. SPENCERSearch for more papers by this author, E. RICHARD KINGSearch for more papers by this author, CHARLES R. HENKELMANNSearch for more papers by this author, THEODORE G. BALBUSSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-48-5-1046 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA useful concept in orienting our thinking about the thyroid is to consider its parameters. The term parameter has gained use in medicine to indicate an arbitrary test for quantitating some aspect of metabolism. For instance, to study the thyroid we can employ such determinations as the basal metabolic rate. But do these arbitrary procedures measure thyroid activity and, if so, can such activity be quantitated? This paper is concerned with an evaluation of parameters proposed for studying the thyroid gland.To be valid, a test of thyroid activity must fulfill two requirements. First, it should measure a function that...Bibliography1. Magnus-Levy A: Ueber den respiratorischen Gaswechsel unter dem Einfluss der Thyreoidea sowie unter verschiedenen pathologischen Zustanden, Berl. klin. Wchnschr. 32: 650, 1895. Google Scholar2. PetersMan JPEB: The significance of serum cholesterol in thyroid disease, J. Clin. Investigation 29: 1, 1950. CrossrefMedlineGoogle Scholar3. StarrLiebhold-Schueck PR: Effect of oral thyroxine and triiodothyronine on radioactive iodine uptake and serum protein-bound iodine in normal human subjects, Proc. Soc. Exper. Biol. and Med. 83: 52, 1953. CrossrefMedlineGoogle Scholar4. Brownell GL: Analysis of techniques for determination of thyroid function with radioiodine, J. Clin. Endocrinol. 11: 1095, 1951. CrossrefGoogle Scholar5. FieldsKinnoryKaplanOesterBowser TDSEYTEN: The determination of the protein-bound I131 with anion exchange resin column, J. Lab. and Clin. Med. 47: 333, 1956. MedlineGoogle Scholar6. Myant NB: Enterohepatic circulation of thyroxine in humans, Clin. Sc. 15: 551, 1956. MedlineGoogle Scholar7. Greer MA: The effect on endogenous thyroid activity of feeding desiccated thyroid to normal human subjects, New England J. Med. 244: 385, 1951. CrossrefMedlineGoogle Scholar8. WernerSpooner SCM: A new and simple test for hyperthyroidism employing 1-triiodothyronine and the twenty-four hour I131 method, Bull. New York Acad. Med. 31: 137, 1955. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication February 8, 1957.From the Radioisotope Laboratory, U. S. Naval Hospital, and the Radioisotope School, U. S. Naval Medical School, National Naval Medical Center, Bethesda, Maryland. The opinions expressed herein are those of the authors, and do not necessarily reflect the views of the Medical Department, or the Naval Service at large.Presented in part at the Maryland-Washington, D. C., District Meeting of The American College of Physicians, January 12, 1957.Requests for reprints should be addressed to Radioisotope Laboratory, U. S. Naval Hospital, Bethesda, Maryland. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDerivation of a chronic oral reference dose for cobalt 1 May 1958Volume 48, Issue 5Page: 1046-1054KeywordsCholesterolExcretionProteinsResearch laboratoriesSalivaThyroid Issue Published: 1 May 1958 PDF downloadLoading ...