tbuckley/cabot-search huggingface dataset:
MSKCC Quality Assessment (QA) monitoring program for potentially harmful chemotherapy orders
Authors: N. T. Sklarin, J. Timoney, L. Kampel, C. Hydzik, J. Savage, M. Capobianco, J. Miransky, J. Haspel
Journal: Journal of Clinical Oncology (2004)

6078 Background: With >150,000 annual doses of chemotherapy at MSKCC, treatment order review plays an integral role in patient safety. To minimize error risk nurses and pharmacists verify all chemo/biologic/immunologic orders. Physicians are contacted for order clarification and ambiguities/errors corrected prior to drug mixing. Methods: To further improve patient safety, a QA program evaluates potentially harmful orders. Prospectively collected data on “Type I” errors are categorized by: wrong/missing drug, wrong frequency, wrong patient, dose > or < 20% of correct dose, wrong administration route. Program participation is voluntary and underreporting of cases is possible. Data forms are sent to QA and on-line Pharmacy Intervention reports document order clarification. Information is not used in a punitive manner; with names of involved staff kept confidential. Trends revealed in case reviews are discussed with staff and individual/group education remedies knowledge deficits. Results: Corrections were made before orders reached patients. In 2002, 91 cases met “Type I” criteria. Infusional therapy over > 24 hrs was identified as an error-prone order. Communication of findings and staff education resulted in a reduction of such prescribing discrepancies. Despite increasing order volumes, from Jan-Nov 2003 only 115 “Type I”s were reported (0.076% of all chemo orders): 84 dose errors (mostly calculation mistakes), 13 frequency, 12 wrong/omitted drug (8 chemo, 4 protectants), 6 patient ID, and 0 incorrect route. Error-prone practices included not continuing dose reductions on subsequent cycles and mismatching doses on multi-drug orders. Conclusions: MSKCC has a highly successful verification/QA program to identify the minute number of potentially harmful orders before they reach patients. Communicating the program's non-punitive nature and its potential to improve patient safety and chemotherapy practice resulted in an increase in reporting and improved detection of error-prone practices in 2003. No significant financial relationships to disclose.
How To Do It: Work in the European Union
Authors: F. Klemperer
Journal: BMJ (1996)

Continental Europe is now only 20 minutes away by train from mainland Britain, and moving ever closer politically. Mutual recognition of medical qualifications within the European Union is well established: working in other parts of Europe is, in principle, straightforward. Working in different health care systems can offer new perspectives on British medical practice and the NHS. But the cultural differences are not always easy to overcome.
Somatostatin receptor expression in stromal tumors of the gastrointestinal tract
Authors: L. Montella, T. Florio, C. Aiello, F. Barbieri, V. Villa, S. Schulz, L. Insabato, G. Palmieri
Journal: Journal of Clinical Oncology (2005)

9042 Background: Imatinib mesylate (STI-571, Gleevec) a small molecule tyrosine kinase inhibitor directed against the enzymatic domain of KIT protein, was recently found to produce dramatic clinical responses as monotherapy for metastatic GISTs. However, imatinib resistance can occur determining treatment failure. The present study was performed to analyse the expression of somatostatin receptor (SSTR) subtypes in a series of Gastrointestinal (GI) stromal tumors by immunohistochemistry and possibly identify an additional therapeutic target. Methods: Sixteen cases of GI stromal tumors (8 males and 8 females, age range: 38–73) were studied. 11 GISTs, 4 leiomyosarcomas, 1 leiomyoma were included. A gastric leiomyosarcoma was doubly evaluated (primitive tumor and metastatic lung lesion). Immunohistochemical detection of SSTRs was performed on sections (4μm) of paraffin-embedded tissue stained with polyclonal antibodies directed against the five somatostatin receptor subtypes. Results: We found 7 out of 16 tumors (44%) expressing all SSTRs and 14 out of 16 (87%) tumors positive for at least 3 subtypes. SSTR2A was the most represented subtype in the tumors studied, being expressed in approximately 70% of cases and usually exhibiting an intense labeling. All GISTs apart one resulted positive for more than two SSTR subtypes. SSTR2A was the most strongly expressed subtype in GISTs (72% of cases). All 4 leiomyosarcomas of this series expressed SSTRs, being SSTR4 and SSTR5 positive in all cases. Conclusions: The significant expression of SSTRs showed in this series of GI stromal tumors suggests a potential therapeutic target to be explored alone and/or in combination with other therapeutic agents in the setting of refractory GI stromal tumors. No significant financial relationships to disclose.
A randomized phase III trial (389): Oral topotecan/cisplatin (TC) vs IV etoposide/cisplatin (PE) as treatment for chemotherapy-naïve patients (pts) with extensive disease small cell lung cancer (ED-SCLC): Interim tolerability results
Authors: J. R. Eckardt, J. Von Pawel, G. Manikhas, Z. Papai, A. Tomova, V. Tzekova, T. Crofts, R. Poulin, J. Levin, G. Ross
Journal: Journal of Clinical Oncology (2004)

7046 Background: IV topotecan is an established therapy in relapsed, “sensitive” SCLC. Oral and IV topotecan have similar activity and tolerability. Phase II data in combination with cisplatin as well as data from Noda et al provided the rationale for this study. Methods: Chemotherapy-naïve patients with ED-SCLC and performance status ECOG 0, 1, or 2 stratified by gender, performance status, LDH, and country were randomized to receive either oral topotecan (days 1–5: 1.7 mg/m2)/cisplatin (day 5: 60 mg/m2) (TC) or IV etoposide (days 1–3: 100 mg/m2)/cisplatin (day 1: 80 mg/m2) (PE). The dose of oral topotecan was reduced from 2.0 mg/m2/day to 1.7 mg/m2/day because of neutropenia and diarrhoea. Primary endpoint was overall survival; secondary endpoints were response rate, response duration, time to progression, tolerability, and symptom improvement. Results: Between May 2001 and December 2002, 859 patients were recruited. Preliminary tolerability data are available for 732 pts (TC: 364/PE: 368). Baseline characteristics were balanced (TC/PE): males: (80%/79%); age 65 years or older: (32%/34%), PS 0–1: (88%/88%). Median number courses: (5/5). Principal adverse experiences per patient incidence are summarized for TC/PE: grade 4 neutropenia (32%/58% p<0.001), platelets <25,000 (10%/6% p=0.069); grade 3/4 anemia (35%/20% p<0.001), febrile neutropenia (1%/4% p=0.02), infection (9%/12% p=0.23), sepsis (3%/0% p =0.006), all grades of nausea/vomiting (58%/39% vs 62%/42% p=0.29/0.45) and diarrhoea - all/grades 3&4 (32%/5% vs 17%/2% p<0.001/0.03). Two patients on TC were hospitalized with enterocolitis. Conclusions: This is one of the largest studies ever conducted in ED-SCLC. Because follow-up is ongoing, efficacy data (including survival) remain blinded. Preliminary tolerability results suggest that both TC and PE regimens can be delivered with manageable toxicities. Author Disclosure Employment or Leadership Consultant or Advisory Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration GlaxoSmithKline GlaxoSmithKline GlaxoSmithKline GlaxoSmithKline GlaxoSmithKline GlaxoSmithKline
Alcohol handrubs v soap
Authors: J. Ojajarvi
Journal: BMJ (2003)

# Finnish experience shows that alcohol rubs are good for hands {#article-title-2} EDITOR—Girou et al compared the use of alcohol based handrubs with standard handwashing.1 Such handrubs have been used in Finland since the 1980s, and handrubbing is the preferred choice for hand hygiene in health care. Healthcare workers have accepted the method, and complaints of dry skin are fewer than with using other hand hygiene products. 2 3 Alcoholic preparations must of course contain skin emollients such as 1-2% glycerol to prevent drying of the skin. 1. 1.↵1. Girou E, 2. Loyeau S, 3. Legrand P, 4. Oppein F, 5. Brun-Boisson C . Efficacy of handrubbing with alcohol based solution versus standard handwashing with antiseptic soap: randomised clinical trial. BMJ 2002; 325: 362 [OpenUrl][1][Abstract/FREE Full Text][2] 2. 2.↵1. Ojajärvi J, 2. Mäkelä P, 3. Rantasalo I . Failure of hand disinfection with frequent hand washing: a need for profield studies. J Hyg 1977; 79: 107–119 [OpenUrl][3] 3. 3.↵1. Ojajärvi J . Handwashing in Finland. J Hosp Infect 1991; 18 (suppl B): 35–40 [OpenUrl][4][PubMed][5] # Alcohol handrub removes methicillin resistant Staphylococcus aureus {#article-title-6} EDITOR—Girou et al showed that handrubbing with an alcohol … [1]: {openurl}?query=rft.jtitle%253DBMJ%26rft.stitle%253DBMJ%26rft.issn%253D0007-1447%26rft.aulast%253DGirou%26rft.auinit1%253DE.%26rft.volume%253D325%26rft.issue%253D7360%26rft.spage%253D362%26rft.epage%253D362%26rft.atitle%253DEfficacy%2Bof%2Bhandrubbing%2Bwith%2Balcohol%2Bbased%2Bsolution%2Bversus%2Bstandard%2Bhandwashing%2Bwith%2Bantiseptic%2Bsoap%253A%2Brandomised%2Bclinical%2Btrial%26rft_id%253Dinfo%253Adoi%252F10.1136%252Fbmj.325.7360.362%26rft_id%253Dinfo%253Apmid%252F12183307%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=bmj&resid=325/7360/362&atom=%2Fbmj%2F326%2F7379%2F50.2.atom [3]: {openurl}?query=rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [4]: {openurl}?query=rft.jtitle%253DThe%2BJournal%2Bof%2Bhospital%2Binfection%26rft.stitle%253DJ%2BHosp%2BInfect%26rft.aulast%253DWesth%26rft.auinit1%253DH.%26rft.volume%253D18%26rft.issue%253D1%26rft.spage%253D35%26rft.epage%253D43%26rft.atitle%253DEvolution%2Bof%2BStaphylococcus%2Baureus%2Bresistance%2Bto%2Berythromycin%2Bin%2BDenmark%252C%2B1959%2Bto%2B1988%253A%2Bcorrelations%2Bbetween%2Bcharacteristics%2Bof%2Berythromycin-resistant%2Bbacteraemia%2Bstrains.%26rft_id%253Dinfo%253Apmid%252F1679070%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [5]: /lookup/external-ref?access_num=1679070&link_type=MED&atom=%2Fbmj%2F326%2F7379%2F50.2.atom
Adjuvant treatment with tamoxifen
Authors: R D Bulbrook
Journal: BMJ (1996)

Orchidopexy before age of 10 is best for undescended testes ED1TOR,-Chris Dawson and Hugh Whitfield's article on common paediatric problems in urology suggests that an intra-abdominal testis diagnosed after the age of 2 should be left in situ to preserve hormonal function until after puberty, when orchidectomy could then be performed.'We are aware of the need for brevity in ABC series, but we think that this suggestion is unusual and open to debate.The authors make no distinction between uni- lateral and bilateral cases of undescended testis.The policy that they advocate confers no obvious endocrine advantage in unilateral cases.In bilateral cases orchidectomy after puberty will neces- sitate long term hormone replacement treat- ment, whereas orchidopexy performed at the time of diagnosis and before the age of 10 years will obviate the need for such treatment while mitigating the potential for malignant degeneration.2 3 Recent studies with long term follow up have shown that even for the impalpable testis, high success rates are achievable with a variety of techniques, including microvascular techniques.4'We assume that the advice in the flowchart for orchidopexy to be performed after puberty in those diagnosed after the age of 2 years is a typographical error as it is at variance with the advice given in the text.
Verification of the newly proposed T category (7<sup>th</sup> edition of the TNM classification) from a clinicopathologic viewpoint in non-small cell lung cancer
Authors: T. Yano, Y. Morodomi, K. Ito, N. Miura, T. Takenaka, D. Kawano, F. Shoji, Y. Maehara
Journal: Journal of Clinical Oncology (2009)

7533 Background: The proposed revision of the TNM classification by the International Association for the Study of Lung Cancer (IASLC) has been determined and validated based on the overall survival data. In the present study, we verified the T classification, which was the major point of revision regarding the newly proposed TNM classification, from a viewpoint of the clinico-pathologic findings at the primary tumor site. Methods: The medical records of 621 patients with primary non-small cell lung cancer (NSCLC) who underwent a complete resection at our institution from 1990 through 2003 were reviewed for the clinico-pathologic variables. The patients ranged in age from 31 to 87 years old with a mean of 66.4. The male:female ratio was 382:239. The adenocarcinoma:non-adenocarcinoma ratio was 449:220. Results: According to greatest dimension of the primary tumors, the 5-year postoperative survival was 77.8% for T1a (2cm&gt;; n=168), 63.3% for T1b (3cm&gt;; n=169), 46.4% for T2a (5cm&gt;; n=205), 38.8% for T2b (7cm&gt;; n=48), and 21.4% for T3 (7cm&lt;; n=31) (p&lt;0.001). The incidence of lymphatic permeation within the primary tumor was 12.5% for T1a, 17.2% for T1b, 29.8% for T2a, 35.4% for T2b, and 32.3% for T3 (T1b vs. T2a p&lt;0.05). The incidence of vascular invasion within the primary tumor was 17.8% for T1a, 24.9% for T1b, 35.3% for T2a, 54.2% for T2b, and 64.5% for T3 (T1b vs. T2a, T2a vs. T2b, p&lt;0.05). On the other hand, the incidence of pleural invasion of the primary tumor was 18.1 % for T1a, 29.4% for T1b, 49.3% for T2a, 47.3% for T2b, and 87.5% for T3 (T1a vs. T1b, T1b vs. T2a, T2b vs.T3, p&lt;0.05). Significant differences were observed among the newly revised T subsets in at least one incidence of lymphatic permeation, vascular invasion or pleural invasion. Conclusions: The newly revised T classification, which is based mainly on the tumor dimension, is therefore considered both effective and appropriate for the pathological findings of the primary tumor. No significant financial relationships to disclose.
What Are You Going to Conquer with the Spear?
Authors: Jun Yu
Journal: Genomics Proteomics & Bioinformatics (2005)

Almost everyone in China knows this story, even elementary school pupils: Once upon a time, there was a weapon salesman claiming with confidence to one crowd that all his spears were capable of piercing every shield that existed in the world, then he turned around and told the other crowd mysteriously that all his shields were not penetrable. A bystander who heard both claims asked him, “How about stabbing your shields with your spears?” It was indeed an unexpected question that made the eloquent salesman mute right on the spot. Since then, the Chinese people have called contradiction as ”mao-dun”, which literally means “the spear (pronounced as “mao”) and shield (pronounced as “dun”)”.
A phase II trial assessing the activity of gemcitabine as second-line chemotherapy in non-small cell lung cancer
Authors: Jean-Paul Sculier, Jean-Jacques Lafitte, Jacques Thiriaux, J. Lecomte, George Koumakis, Thierry Berghmans, Vincent Ninane, Paul Mommen, Marianne Paesmans, Jean Klastersky
Journal: European Respiratory Journal (1999)
Abstract 10099: Adaptive Servo-ventilation Therapy Improves Long-term Prognosis in Heart Failure Patients With Anemia and Sleep-disordered Breathing
Authors: Satoshi Suzuki, Akiomi Yoshihisa, Takeshi Shimizu, Hiroyuki Yamauchi, Takashi Owada, Makiko Miyata, Satoshi Abe, Takamasa Sato, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazto, Hitoshi Suzuki, Shu-ichi Saitoh, Yasuchika Takeishi
Journal: Circulation (2013)

Backgrounds: Sleep-disordered breathing (SDB) influences the progression of chronic heart failure (CHF), and adaptive servo ventilation (ASV) is an effective therapeutic device for SDB. Anemia is a...
Plasma Catecholamines and Lipoproteins in Chronic Psychological Stress
Authors: L O'Donnell, N O'Meara, D Owens, A Johnson, P Collins, G Tomkin
Journal: Journal of the Royal Society of Medicine (1987)

Changes in plasma catecholamines, lipoproteins and dietary intake were examined in 13 medical students during a 3-month period prior to their examinations, and in 12 controls. In the medical students mean ± s.e.(mean) plasma cholesterol increased over the study period (3.98 ± 0.16 v. 4.26 ± 0.16 mmol/l, P &lt; 0.05) and this was reflected by a rise in low-density lipoprotein cholesterol (2.53 ± 0.15 v. 2.71 ± 0.17 mmol/l, P &lt; 0.05). Both supine adrenaline (0.45 ± 0.05 v. 0.70 ± 0.07 nmol/l, P &lt; 0.01) and noradrenaline (2.74 ± 0.18 v. 3.40 ± 0.31 nmol/l, P &lt; 0.05) increased over this period. Apart from a decline in the modest alcohol consumption (9.1 ± 3.45 v. 2.6 ± 1.4 g/day, P &lt; 0.02) there was no change in dietary intake in the medical students. There were no significant changes in plasma catecholamines, lipoproteins or dietary intake in control subjects over the study period. Changes in catecholamines and lipoproteins occurring in association with chronic psychological stress may contribute to the increased coronary heart disease mortality associated with Type A behaviour and stressful life events.
Fractures and Dislocations. Immediate Management, After-Care, and Convalescent Treatment With Special Reference to the Conservation and Restoration of Function.
Authors: Philip D. Wilson, William A. Cochrane
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CD30 Ligand Is Frequently Expressed in Human Hematopoietic Malignancies of Myeloid and Lymphoid Origin
Authors: Valter Gattei, Massimo Degan, Annunziata Gloghini, Angela De Iuliis, Salvatore Improta, Francesca Maria Rossi, Donatella Aldinucci, Vilma Perin, Diego Serraino, Roberta Babare, Vittorina Zagonel, Hans-Jürgen Gruss, Antonino Carbone, Antonio Pinto
Journal: Blood (1997)
Über die Pathologie der vegetativen nervösen Peripherie und ihrer ganglionären Regulationsstätten
Authors: F. Feyrter
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Internet-based recruitment system for HIV and STI screening for men who have sex with men in Estonia, 2013: analysis of preliminary outcomes
Authors: K Rüütel, L Lõhmus, J Jänes
Journal: Eurosurveillance (2015)

The aim of the current project was to develop an Internet-based recruitment system for HIV and sexually transmitted infection (STI) screening for men who have sex with men (MSM) in Estonia in order to collect biological samples during behavioural studies. In 2013, an Internet-based HIV risk-behaviour survey was conducted among MSM living in Estonia. After completing the questionnaire, all participants were offered anonymous and free-of-charge STI testing. They could either order a urine sample kit by post to screen for chlamydia infections (including lymphogranuloma venereum (LGV)), trichomoniasis, gonorrhoea and Mycoplasma genitalium infections, or visit a laboratory for HIV, hepatitis A virus, hepatitis B virus,hepatitis C virus and syphilis screening. Of 301 participants who completed the questionnaire, 265 (88%),reported that they were MSM. Of these 265 MSM,68 (26%) underwent various types of testing. In the multiple regression analysis, Russian as the first language,previous HIV testing and living in a city or town increased the odds of testing during the study. Linking Internet-based behavioural data collection with biological sample collection is a promising approach. As there are no specific STI services for MSM in Estonia,this system could also be used as an additional option for anonymous and free-of-charge STI screening.
Low-Dose IL-2 Induces Bcl2 Expression and Resistance To Apoptosis In CD4 Regulatory T Cells
Authors: Kazuyuki Murase, Yutaka Kawano, Jeremy Ryan, Ken-ichi Matsuoka, Gregory Bascug, Sean McDonough, Robert W Smith, Kristen Cowens, Suzan Lazo-Kallanian, John Daley, John Koreth, Robert J. Soiffer, Anthony Letai, Jerome Ritz
Journal: Blood (2013)
Primary Liposarcoma of the Orbit
Authors: Frederick A. Jakobiec, Frank Rini, Devron Char, James Orcutt, Jack Rootman, Henry Baylis, Joseph Flanagan
Journal: Ophthalmology (1989)

The clinicopathologic features and the results of diagnostic studies were reviewed in five patients with primary orbital liposarcoma. The major clinical complaints were diplopia and proptosis; visual function was typically well maintained. In three cases, computed tomographic (CT) scans displayed lesions with a central fat density rimmed by a variably radiodense pseudocapsule, leading to the erroneous clinical impression that the lesions were cystic in character. Ultrasonography ruled out a truly cystic tumor by demonstrating internal acoustic interfaces. Magnetic resonance imaging (MRI) in one case showed hyperintense signals in T-1-weighted images, suggesting the presence of fat within the lesional tissue. In the other two cases, CT scans showed reticulated densities accentuating the septa of the orbital fat in the absence of clear-cut circumscription. A potentially useful feature pointing to a neoplasm was bowing of an involved extraocular muscle, which is usually straightened and splinted in either Graves' disease or inflammatory pseudotumor. Histopathologically, two lesions were well-differentiated liposarcomas and three were myxoid liposarcomas, all featuring univacuolar signet ring lipoblasts. Scattered bizarre hyperchromatic mesenchymal cells without prominent lipidization were present in the lesions. None of the patients has experienced regional or distant metastases with follow-ups from onset of 1 to 7 years (mean, 5.2 years); three required orbital exenteration after local recurrence; and two who refused exenteration received only orbital radiotherapy.