tbuckley/cabot-search huggingface dataset:
The Etiology of Osseous Deformities of the Head, Face, Jaws and Teeth
Authors: Eugene Solomon Talbot Talbot
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE TREATMENT OF ILLNESS OF EMOTIONAL ORIGIN BY THE INTERNIST
Authors: Edward Weiss
Journal: Annals of Internal Medicine (1940)

Article1 September 1940THE TREATMENT OF ILLNESS OF EMOTIONAL ORIGIN BY THE INTERNISTEDWARD WEISS, M.D., F.A.C.P.EDWARD WEISS, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-3-424 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBetween the small number of obviously psychotic people whom an internist sees and the larger number of patients who are sick solely because of organic disease are a vast number of sick people who are not "out of their minds" and yet who do not have any definite bodily disease to account for their illness.It is reliably estimated that about one-third of the patients who consult the internist fall into this group. These are the so-called purely functional problems of medical practice. Approximately another third of the patients who consult an internist seem to have symptoms that are in... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: EDWARD WEISS, M.D., F.A.C.P.Affiliations: Philadelphia, Pennsylvania*Read at the Cleveland meeting of the American College of Physicians April 5, 1940.Department of Medicine, Temple University School of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe problem of acute abdominal painThe neurotic patient. A discussion of the causes and treatment of neurosis 1 September 1940Volume 14, Issue 3Page: 424-435KeywordsEmotionsFalls ePublished: 1 December 2008 Issue Published: 1 September 1940 PDF downloadLoading ...
Keep Your Voice Healthy: A Guide to the Intelligent Use and Care of the Speaking and Singing Voice
Authors: Friedrich Samuel Brodnitz
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Can students learn comparable clinical skills in general practice and hospital settings?
Authors: S. Hartley, A. Berlin, N. Tolley, J. Hobson, D. M Reid, E. Murray, M. Modell, B. Jolly
Journal: BMJ (1998)

Majority view of climate scientists is that global warming is indeed happeningEditor-Gardner states that the scientific basis of climate change is uncertain and that there are major differences of opinion among climatologists about whether climate change is likely to occur and its potential magnitude. 1 Inevitably, with an issue of such complexity there is bound to be scientific debate, but the Intergovernmental Panel on Climate Change, which we quoted in our articles, is a major international collaboration: it has involved the participation of over 2500 scientists from around the world.Many of the most vociferous sceptics have received funding from fossil fuel industries, which clearly have a vested interest in opposing changes in policy that might result in shifts away from fossil fuels. 2 The evidence that Gardner quoted against climate change-that satellite data have shown 0.13°C global cooling between 1979 and 1994 and that the Arctic has been cooling-is mistaken.Satellite measurements are in good agreement with records of surface temperature for 1979-94. 3 Once the transient effects of volcanoes and the El Niño-southern oscillation are removed, upward global trends of 0.09°C per decade from satellite data and 0.17°C per decade from surface data are obtained. 4 This is reasonable agreement, especially when one realises that the satellite measurement is a weighted average over the atmosphere column from the surface to 7 km altitude and temperature changes in the midtroposphere may well differ from those at the surface.Furthermore, although temperatures have fallen in Greenland, they have risen by similar amounts over much of the remaining Arctic, notably in Siberia, northern Canada, and Alaska. 5 There is compelling evidence that the average global temperature has increased by about 0.6°C since the industrial revolution.Indeed, nine of the 11 hottest years this century have occurred since 1985.More importantly, climate models suggest that substantial global warming (1.0-3.5°C) will have occurred by the end of the next century with projected increases in use of fossil fuels.This underlines the need for a precautionary approach to limit emissions of greenhouse gases as well as increased investment in research on climate change and its potential impacts.Finally, we must emphasise that the prospect of large scale climate and environ-mental changes necessitates the contingent assessment of future risks.Epidemiologists (like agricultural scientists, hydrologists, urban planners, and others) cannot reasonably dispute the majority view of climate scientists.Rather, they must base their risk assessment on the climate change scenarios projected by those experts.
Abstract 3358: Multibiomarker Approach Predicts Adverse Cardiovascular Outcomes in Women Evaluated for Suspected Ischemia without Obstructive CAD Better than Traditional Risk Predictors: Results from the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation (WISE)
Authors: Christopher B Arant, B. Delia Johnson, Timothy R Wessel, Gregory O Von Mering, Eileen Handberg, Karen M Smith, Daniel F Pauly, Steven E Reis, Barry Sharaf, George Sopko, Noel Bairey Merz, Carl J Pepine
Journal: Circulation (2006)

Background Inflammatory markers and low hemoglobin (Hgb) levels predict adverse cardiovascular (CV) outcomes in selected populations. The evaluation of traditional risk predictors in this context i...
Neuroprotective peptides fused to arginine-rich cell penetrating peptides: Neuroprotective mechanism likely mediated by peptide endocytic properties
Authors: Bruno P. Meloni, Diego Milani, Adam B. Edwards, Ryan S. Anderton, Ryan L. O'Hare Doig, Melinda Fitzgerald, T. Norman Palmer, Neville W. Knuckey
Journal: Pharmacology & Therapeutics (2015)
Vasa Vasorum Restructuring in Human Atherosclerotic Plaque Vulnerability
Authors: Akira Taruya, Atsushi Tanaka, Tsuyoshi Nishiguchi, Yoshiki Matsuo, Yuichi Ozaki, Manabu Kashiwagi, Yasutsugu Shiono, Makoto Orii, Takashi Yamano, Yasushi Ino, Kumiko Hirata, Takashi Kubo, Takashi Akasaka
Journal: Journal of the American College of Cardiology (2015)
Quality of life (QOL) in patients (Pts) with hormone resistant prostate cancer (HRPC) treated with docetaxel (D) and celecoxib (C)
Authors: V. T. Chang, N. Sambamoorthi, H. Yan, M. Gonzalez, J. Cogswell, S. Srinivas, F. Zhong, B. Crump, M. Blumenfrucht, B. S. Kasimis
Journal: Journal of Clinical Oncology (2006)

18598 Background: The impact of chemotherapy on QOL for pts with HRPC is not well described. Thirty patients(30) participated in a trial of D and C(Kasimis et al, submitted ASCO 2006). The objectives for this companion study were to study QOL outcomes with the FACT instrument including the Prostate subscale(FP) and utility from the EQ5D. Methods: In a phase II trial, 30 pts with progressive HRPC were treated with D and C for 4 wks in each cycle. Response evaluation was made by RECIST criteria and PSA reduction by &gt;50% for biochemical response every 2 cycles. Patients completed the FACT and EQ5D instruments at the beginning of every cycle. We analyzed the FACT subscales with different statistical approaches, and compared FACT and utility for responders and non responders. Results: All 30 pts accrued were evaluable for toxicity and response. Thirty (30) pts received a minimum of 2 cycles, median (M) 4.5 (range 2–8). The M age was 74 yr (55–94), ECOG PS 1 (0–2). For 19 pts, the baseline mean score for the FACT P was 29, Standard Deviation 10. The Cronbach’s Coefficient was 0.83. The FACT Physical Well Being (PWB) correlated with the EQ5D utility score 0.76 (p &lt; .0003), as did the Functional Well Being (FWB) 0.67 (p &lt; .003) and FACT P 0.62 (p &lt; .006). The FACT PWB, EWB, FP, Treatment Outcome Index, and EQ5D Utility differed significantly between responders and non responders by radiographic parameters, alpha = 0.1. The results for PSA reduction &gt;50% are similar. Conclusions: The FACT Prostate subscale has good psychometric properties, correlates with EQ5D utility measure, and also with responder status by radiography and PSA. [Table: see text]
Large circular sense and antisense libraries for target validation
Authors: Kyung-Oh Doh, Jong-Gu Park
Journal: Clinical Cancer Research (2007)

A68   A high-throughput validation of genes associated with cancer cell growth was attempted via the combination of large circular (LC)-sense and antisense libraries. The single-stranded LC-sense molecules were utilized as probes for DNA microarrays, and evidenced binding signals stronger than those of the PCR-amplified cDNA probes under identical hybridization conditions. In the microarray experiment using 284 LC-sense DNA probes, 6 genes were determined to be upregulated, and 7 genes were downregulated in the A549 cells, as compared to the WI38VA13 cells. These results correlated strongly with data acquired from quantitative real-time RT-PCR. An analysis using a large array comprising 5,079 LC-sense DNA probes indicated that 332 (~6.54%) and 509 (~10.02%) were up and downregulated respectively in lung cancer cells. Subsequent functional analysis using an LC-antisense library of the overexpressed genes allowed identification of 131 genes involved in cancer cell growth. These experiments demonstrate the potential utility in the combination of LC-sense and antisense libraries for an effective high-throughput functional validation of genes.
Diagnostic Accuracy of Coronary Computed Tomography Angiography
Authors: Gianluca Pontone, Daniele Andreini, Antonio L. Bartorelli, Sarah Cortinovis, Saima Mushtaq, Erika Bertella, Andrea Annoni, Alberto Formenti, Enrica Nobili, Daniela Trabattoni, Piero Montorsi, Giovanni Ballerini, Piergiuseppe Agostoni, Mauro Pepi
Journal: Journal of the American College of Cardiology (2009)
History and organization of palliative care in Poland
Authors: E. Swietlik, A. Doboszynska
Journal: Journal of Clinical Oncology (2009)

e20749 Beginning of the hospice care in Poland is associated with democratic opposition in the eighties of the XX century and social movement Solidarity. In 1978, C. Saunders visited Gdansk, Warsaw, and Krakow, supporting an organization of palliative care in Poland. Polish hospice care, similarly to other countries,originated from the necessity of special care of terminally ill cancer patients. Palliative care societies, initially informal, then registered formally, emerged in Poland in 1981. Hospices, both institutional and house hospice care, came into being in all larger cities in Poland to the nineties of the XX century. In 1991, National Forum of the Hospice Movement was founded. This Forum, gathering the majority of hospices, is actually transformed into the association of societies: Forum of the Polish Hospices. In the nineties of the XX century, professional palliative care developed. Since 1998, specialization in the palliative care for both physicians and nurses is available. From the very beginning, hospice care based on the volunteers gathered at the Roman Catholic parish and several priests first organized palliative care. In 1991, The Sejm (lower chamber of the Polish Parliament) passed the law Health care institutions, enabling various societies and associations to establish health care institutions, whereas the law The Social Insurance Act (1997) gives an opportunity to get financial means for hospice care from the State. Actually, there are hospices acting on voluntary service (the number of such hospices decreases), partial voluntary service and also paid employees, and institutions which activities are based on full-time employment and financed by the National Health Fund. About 130 non-profit societies and hospice foundations both secular andchurch exist in Poland. Non-public health care institutions founded 99 hospices. About 70 hospices (both public and private) are stationary. No significant financial relationships to disclose.
Abstract 14862: Prediction of Myocardial Infarct Size Using Multiple Concomitant Angiographic, Biochemical and Electrocardiographic Biomarkers in Patients with ST-Segment Elevation Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention
Authors: Wichert J Kuijt, Mitchell W Krucoff, Peter Damman, Renato D Lopes, Cindy L Green, Karen S Pieper, Susanna R Stevens, Robert H Christenson, Jan G Tijssen, Gregg W Stone, A M Lincoff, Robbert J de Winter, Matthew T Roe
Journal: Circulation (2011)

Background Despite significant improvement in clinical outcome with primary percutaneous coronary intervention (pPCI), ST-segment elevation myocardial infarction (STEMI) remains associated with con...
International Health HistoryInternational Health History
Authors: Markley H. Boyer
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RENAL INSUFFICIENCY WITH TETANY IN AN ADULT; REPORT OF A CASE
Authors: E. Perry Mccullagh, E. J. Ryan
Journal: Annals of Internal Medicine (1939)

Case Reports1 August 1939RENAL INSUFFICIENCY WITH TETANY IN AN ADULT; REPORT OF A CASEE. PERRY MCCULLAGH, M.D., F.A.C.P., E. J. RYAN, M.D.E. PERRY MCCULLAGH, M.D., F.A.C.P.Search for more papers by this author, E. J. RYAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-13-2-351 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCASE REPORTThe patient was a Jewish woman, 48 years of age. Her symptoms appeared in 1905 when she was 29 and in her second pregnancy. At that time, she had the first of a long series of attacks which were characterized primarily by weakness of the muscles of the extremities of such severity that she was unable to walk or to raise her hands or arms. These attacks, varying in severity but essentially similar in character, continued to occur in this form at irregular intervals of one to six months until six months before she came under our observation... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Received for publication June 2, 1938. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie Tetanie des Erwachsenen und ihre Grenzzustände 1 August 1939Volume 13, Issue 2Page: 351-357KeywordsMusclesPregnancy Issue Published: 1 August 1939 PDF downloadLoading ...
Die Wirbelsäulentuberkulose und ihre Differentialdiagnose
Authors: J. E. W. Brocher
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Acute Renal Failure: Diagnosis, Treatment, and Prevention
Authors: Kim Solez, Lorraine C. Racusen
Journal: Annals of Internal Medicine (1991)

Thirty-four papers from the Symposium on Acute Renal Failure, held in September 1988 (place unspecified), emphasize in particular: areas where investigations of pathogenesis in experimental systems could be applied to develop new clinical strategies for treatment and prevention of acute renal failur
Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation
Authors: De-Hua Chui, Hiroshi Tanahashi, Kazuharu Ozawa, Sachiya Ikeda, Frédéric Checler, Otoya Ueda, Hiroshi Suzuki, Wataru Araki, Haruhisa Inoue, Keiro Shirotani, Keikichi Takahashi, Ferenc Gallyas, Takeshi Tabira
Journal: Nature Medicine (1999)
Abstract 1597: Safety and Efficacy of Inhaled Iloprost Via a Disposable Nebulizer in Heart Failure Patients With Elevated Pulmonary Vascular Resistance
Authors: David Baran, Luis H Arroyo, Jill Hebron, Candace Carr, Mark J Zucker
Journal: Circulation (2007)

Background : Pulmonary vascular resistance (PVR) is routinely measured in patients (pts) being evaluated for a heart transplant. Pts with a high PVR are often treated with a milrinone or intravenous vasodilator “challenge” to establish that the PVR is not “fixed”. However, all current agents have dose-limiting side effects such as arrhythmias and hypotension. Inhaled iloprost would be an option but it is given with a costly adaptive aerosol delivery device. In addition, the efficacy and safety of this drug in left heart failure is poorly studied. Methods : 10 adult heart failure pts who were found to have a PVR of greater than 200 dyne-sec on routine right heart catheterization were enrolled. 50 micrograms (mcg) of iloprost was inhaled while in the catheterization laboratory using a disposable nebulizer and outflow filter, over 10 minutes. Hemodynamics were monitored at baseline, following drug inhalation, and 20 minutes later. Results : The average age of the patients (6 male, 4 female) was 64.8 ± 8.9 years. The mean left ventricular ejection fraction was 20.6 ± 8.6 %. The mean creatinine clearance (Cockroft-Gault) was 48.7 ± 18.9 ml/hr. The mean arterial pressure (MAP), pulmonary artery systolic (PAS), PA diastolic (PAD), PCWP, transpulmonic gradient (TPG), cardiac output (CO), and PVR at baseline, 10 minutes and 20 minutes post-inhalation are detailed below. Iloprost significantly reduced PAS, TPG and PVR without changes in MAP, PAD, PCWP or CO. These effects remained significant at study completion as well. There were no adverse events noted. Conclusion : Iloprost inhalation was well tolerated in heart failure patients undergoing right heart catheterization. Inhalation of 50 mcg of iloprost via a simple hospital nebulizer was associated with safe, rapid, and significant declines in indices of pulmonary vascular tone, without affecting cardiac output or PCWP. Further investigation of this novel use of iloprost is warranted. Results
Letters to the Editor: Does Alpha-interferon in conjunction with radiotherapy increase the risk of complications in the central nervous system?
Authors: H. Hagberg, E. Blomkvist, U. Ponten, L. Persson, C. Muhr, B. Eriksson, K. Öberg, Y. Olsson, A. Lilja
Journal: Annals of Oncology (1990)

Does alpha-interferon in conjunctions with radiotheraphy increase the risk of complications in the central nervous system?