CLINICAL EVALUATION OF AUROTHIOGLYCOLANILIDE (LAURON-ENDO) IN RHEUMATOID ARTHRITIS
Authors: R R MERLISS, B AXELROD, J FINEBERG, M MELNIK
Journal: Annals of Internal Medicine (1951)

Article1 August 1951CLINICAL EVALUATION OF AUROTHIOGLYCOLANILIDE (LAURON-ENDO) IN RHEUMATOID ARTHRITISREUBEN R. MERLISS, BERNARD AXELROD, JOSEPH FINEBERG, MORRIS MELNIKREUBEN R. MERLISSSearch for more papers by this author, BERNARD AXELRODSearch for more papers by this author, JOSEPH FINEBERGSearch for more papers by this author, MORRIS MELNIKSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-35-2-352 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA gold preparation, characterized by slow absorption after intramuscular injection, has recently been studied in the treatment of rheumatoid arthritis. This preparation, aurothioglycolanilide (Lauron, Endo products), has been the subject of three clinical reports, all of them favorable and all pointing out the lesser incidence of toxicity from this compound as compared with the soluble gold preparations.In 1944, Stengel1 treated 30 cases of rheumatoid arthritis with aurothioglycolanilide and found that three cases became completely arrested, 17 showed marked improvement, seven showed moderate improvement and three showed slight to no improvement.Robinson2reported on 55 cases treated with aurothioglycolanilide and...Bibliography1. Stengel E: A new compound for treatment of rheumatoid arthritis, Bull. Hosp. Joint Dis. 5: 114-121, 1944. Google Scholar2. Robinson D: A new gold preparation for the treatment of rheumatoid arthritis, Canad. M. A. J. 53: 279-281, 1945. MedlineGoogle Scholar3. Rose PA: Results with a new gold compound, Illinois M. J. 92: 175-181, 1947. MedlineGoogle Scholar4. ShortBauer CLW: Course of rheumatoid arthritis in patients treated by simple medical and orthopedic measures, New England J. Med. 238: 142-148 (Jan. 29) 1948. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Los Angeles, California*Received for publication April 3, 1950.From the Arthritis Clinic, Cedars of Lebanon Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRole of Echocardiography in the Assessment of Left Ventricular Thrombus Embolic Potential After Anterior Acute Myocardial InfarctionIntramuscular versus oral gold therapyThe history of gold therapy in rheumatoid diseaseWorth its Weight ?Gold Therapy in Rheumatoid Arthritis: Report of a Multi-Centre Controlled TrialSkin Complications of Gold TreatmentSkin eruptions with gold therapy—influence of sesame oilRHEUMATISM AND ARTHRITIS REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (ELEVENTH RHEUMATISM REVIEW)* Part IIWILLIAM D. ROBINSON, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., DARRELL C. CRAIN, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., CHARLES RAGAN, M.D., F.A.C.P., MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P., CHARLEY J. SMYTH, M.D., F.A.C.P.Rheumatoid arthritis: A review of recent advances in our knowledge concerning pathology, diagnosis, and treatment 1 August 1951Volume 35, Issue 2Page: 352-357KeywordsArthritisHospitalsIntramuscular injectionsRheumatoid arthritisToxicity ePublished: 1 December 2008 Issue Published: 1 August 1951 PDF downloadLoading ...