tbuckley/cabot-search huggingface dataset:
Hemobilia due to adenocarcinoma of the gallbladder, an exceptional cause of upper gastrointestinal bleeding
Authors: J. Escobar Ortiz, J. Pérez Pérez, G. G. Francisco, P. D. Angel, A. Martinez-Alcalá
Journal: Endoscopy (2024)

Abstract Text A 71-year-old woman with no medical history presented with melenic stools with significant acute anemia. Gastroscopy revealed active bleeding at the level of the ampulla of Vater, suggestive of hemobilia. A study was completed with Doppler ultrasound+CT+abdominal MRI, which revealed a hyperuptake vesicular lesion, which pointed to neoplastic origin. Finally, surgery was performed, compatible with gallbladder adenocarcinoma (pT3N1) [1].
Endoscopic approach of pyloric dysfunction after esophagectomy – a tertiary oncologic centre’s cohort
Authors: M. Saraiva, D. Conceição, L. Correia Gomes, P. Currais, C. Simões, J. Moleiro, P. Ramos, C. Ramos, R. Ramos, I. Rosa, I. Claro
Journal: Endoscopy (2024)

Aims Pyloric dysfunctions are frequent adverse effects of esophagectomies with significant impact on quality of life. For patients refractory to medical therapy, the endoscopic approach (pneumatic dilation; botulinum toxin injection; G-POEM; biodegradable stents) is the subsequent option.
Ovesco clip closure of colo-vaginal fistula in diverticulitis
Authors: P. Chintan, P. N. Desai, K. Mayank, M. Rajiv, S. Nandwani, P. Ritesh, N. Patel, M. Sethia, R. Kakadiya
Journal: Endoscopy (2024)

Abstract Text 90 year/female. H/o passing stool per vagina since 1 month. H/o of diverticulitis. CECT Abdomen was s/o colo-vaginal fistula. colonoscopy confirmed diverticular disease of left colon without fistula. An UGI scope was introduced per Vagina to evaluate the fistula. After localization, a guide wire was placed for localization of fistula on colonic site. Because of very small size, a decision was taken to make the fistulous track raw with use of brush followed by closure with cyanoacrylate glue. This didn't work. An attempt of Ovesco clip closure was considered in view of age and co-morbidities. Methylene blue was injected surrounding the glide wire for future reference. A site marking was done with dual knife. A glide wire was then removed and ovesco clip was applied where the site was marked.
Unusual access for biliary cholangioscopy with lithotripsy: every cloud has a silver lining
Authors: E. Marconato, P. Farris, A. Dequarti, G. Antonelli, M. Comberlato, F. Desideri
Journal: Endoscopy (2024)

Abstract Text We present an unusual case, in which a "simple" clinical scenario such as cholangitis proved itself more complex than expected. Intuition and out-of-the-box use of advanced endoscopic devices were crucial in this situation. In detail, as you will see in the video, we were able to solve the case performing cholangioscopy through an unusual access to the biliary tract, which allowed us to drain the biliary tree and extract stones less invasively. The case demonstrates the high versatility of this device in the clinical practice.
Radiofrecuency as an alternative treatment for actinic proctitis instead of argon plasma
Authors: R. Honrubia Lopez, E. Montiel Portillo, C. Fernandez De Castro, L. Ciriano Hernandez, C. Comas Redondo
Journal: Endoscopy (2024)

Aims Radiofrequency is a thermal treatment mostly used for Barrett esophagus. This therapy can make an extensive thermal ablation of the mucosa and this fact could be used for treat diffuse mucosal pathology like in actinic proctitis.
Clinical Impact of PillCam Crohn&amp;apos;s Capsule Endoscopy in Inflammatory Bowel Disease Management
Authors: J. Goncalves, A. I. Ferreira, T. Lima Capela, J. Magalhães, B. Rosa, J. Cotter
Journal: Endoscopy (2024)

Aims PillCam Crohn's Capsule (PCC) enables comprehensive examination of the entire gastrointestinal tract, offering high diagnostic yield for small bowel and colonic inflammation in Crohn's disease (CD) patients. Despite its potential, limited research has focused on the clinical implications of PCC in routine clinical practice. This study aimed to investigate the clinical impact of PCC in the management of inflammatory bowel disease (IBD) patients.
Endoscopic Submucosal Resection of Gastric Neoplasm: A Single Center Experience
Authors: I. Kim, Y. S. Kim, J. S. Moon
Journal: Endoscopy (2024)

Aims Gastric adenocarcinoma after endoscopic submucosal resection (ESD) is a major clinical concern. This study aims to show the characteristics of ESD lesions and determine the rate of occurrence of gastric neoplasm
Endoscopic submucosal dissection in a patient with gastric gastrointestinal stromal tumor after downstaging with imatinib therapy
Authors: S. Sud, S. Koul, A. Mishra, S. R. Mishra, A. S. Puri, R. Sud
Journal: Endoscopy (2024)

Abstract Text 41 year old male Patient came with Gastrointestinal bleed. Endoscopy showed a large submucosal growth in proximal body of stomach. Endoscopic ultrasound revealed this to be a 65*50 mm size lesion arising from muscularis mucosa. Biopsy confirmed it to be a gastrointestinal stromal tumor. In view of large size, possibility of difficult retrieval post endoscopic resection was likely. Patient was prescribed imatinib 400 mg once a day for 3 months which regressed the size of the tumor to 25*30 mm making it amenable for endoscopic submucosal dissection and successful retrieval. Patient underwent endoscopic submucosal dissection of this tumor successfully with histopathology confirming CD 117 positivity and peripheral margins free of any tumor. He continues to do well 6 months post resection. [1] [2]
Myth vs. Reality: A Critical Review of Liver Cirrhosis Information Available on YouTube
Authors: R. M. Ram mohan, M. Joy, D. Natt, S. G. Magam, S. R. Magam, L. Pannikodu, J. Desai, P. Mustacchia
Journal: Endoscopy (2024)

Aims The internet, particularly YouTube, is a popular health information source for many. However, studies suggest that patient information on YouTube is often of poor quality. This study aims to evaluate the content and quality of YouTube videos on Liver cirrhosis. With over a billion users, YouTube's widespread use doesn't guarantee quality, as videos, including those on liver cirrhosis, aren't subjected to an editorial process. This can lead to misinformation, potentially skewing users' understanding of their health conditions.
&amp;quot;Evaluating Ethnic Impact on Post-Bariatric Liver Cirrhosis Remission: Insights from Kaplan-Meier Analysis&amp;quot;
Authors: R. M. Ram mohan, M. Joy, S. G. Magam, D. Natt, S. R. Magam, L. Pannikodu, J. Desai, P. Mustacchia
Journal: Endoscopy (2024)

Aims Racial disparities significantly affect mortality rates in patients with ascites and liver cirrhosis. Studies indicate that minority groups, particularly African Americans and Hispanics, often exhibit higher mortality rates. This may be attributed to socioeconomic and genetic predispositions, late-stage diagnoses, and limited access to liver transplantation. Addressing these disparities is essential to improve survival outcomes, advocating for equitable healthcare access and early, accurate diagnosis across all racial and ethnic groups.
Duodenal endoscopic submucosal dissection and clip-assisted endoscopic suturing using the string-clip method
Authors: S. Bassioukas, C. Katzakis, D. Gkaragkanis, B. Kosmidis, M. Chatzinikolaou
Journal: Endoscopy (2024)

Abstract Text Closure of the post-ESD duodenal ulcer bed using endoscopic clips can decrease the risk of delayed bleeding and perforation. We present the case of a dysplastic adenoma of the 2nd part of the duodenum dissected using the pocket-creation ESD method. After ESD completion, clip-assisted endoscopic suturing using the String-Clip method was applied. The clip with an attached suture is released at the distal end of the ulcer grasping both the mucosa and the underlying muscle layer. Then the suture is pulled proximally and a second clip is applied at the proximal end of the ulcer. The central part of the defect is sealed tight and following closure of the peripheral ends with clips is thus feasible. The suture was then cut using endoscopic scissors. [1]
Persistent biliary leak despite ERCP stenting- post hydatid surgery, glue to rescue
Authors: P. Chintan, P. N. Desai, K. Mayank, M. Rajiv, S. Nandwani, P. Ritesh, N. Patel, M. Sethia, R. Kakadiya
Journal: Endoscopy (2024)

Abstract Text A 30 year old female. past history of epigastric pain and vomiting.CECT abdomen was s/o 9*8*7 cm sized hydatid cyst. She underwent laparoscopic deroofing and drainage. She developed biliary leak after 1 month. She was offered a conservative management for a period of 2 weeks which failed to resolve a leak. Patient underwent ERCP which showed a segment II biliary leak. A 7 Fr DPT biliary stent was placed. Despite of biliary decompression for a period of 2 months, biliary leak was persistent. Repeat ERCP-Cholangiogram showed a persistent contrast leak with a small thin tract. The tract was made raw with a use of brush. A balloon catheter was passed till the site of fistula.1 ml of cyanoacrylate glue f/b lipiodol was injected to close the tract. Repeat cholangiogram showed the closure of biliary fistula and no contrast leak.
Endoscopic management of colonic perforation and extra-colonic arterial bleeding after polyp resction by hybrid-ESD
Authors: I. C. Nedelcu
Journal: Endoscopy (2024)

Abstract Text We present the case of a 81yo patient with a lateral spreading tumor located on a colonic fold, at the hepatic flexure. The lesion was engaged by hybrid-ESD technique, in order to ensure en-bloc resection and to minimize procedural time. Complete resection was followed by full-thickness perforation and arterial bleeding. Closer examination revealed the bleeding vessel was located outside the colon (in the pericolonic fat). The vessel was clipped through the colonic parietal defect and then the defect was completely closed (surrounding the clips used for hemostasis). This endoscopic management was followed by 5 days of iv antibiotics and the patient was then discharged without any complications and without the need for surgical intervention.
The yield of ERCP in symptomatic portal cavernous cholangitis
Authors: S. Hmimass, M. Borahma, F. Z. Chabib, M. Kadiri, C. Berhili, I. Benelbarhdadi, N. Lagdali, F. Z. Ajana
Journal: Endoscopy (2024)

Methods This was a mono-centric retrospective study conducted over a 6-year period (2016-2023). We included all patients followed for chronic portal thrombosis complicated by PCC and who received endoscopic treatment.
Cholangioscopy with Electrohydraulic lithotripsy for treatment of remnant cystic duct lithiasis: a suitable therapy for surgical unsuitable patients
Authors: P. Apolito, M. Bassi, S. Landi, S. Ghersi, V. Cennamo
Journal: Endoscopy (2024)

Abstract Text A 60-year-old woman, with a past medical history of cholecystectomy,was admitted to our department for jaundice, fever and leukocytosis. Computerized Tomography scan showed a dilated remnant cystic duct (RCD) with thickened and hyperintense walls, without clear evidence of stones. EUS evaluation showed an enlarged RCD with thickened and hypoechoic walls with a 15 mm stone inside. The patient, unsuitable for surgery and after unsuccessful stones clearance using conventional ERCP techniques, underwent cholangioscopy which showed 2 impacted 15-mm RCD stones that were fragmented using electrohydraulic lithotripsy. Stone fragments were removed by Fogarty balloon. Final contrast fluoroscopy and second look cholangioscopy excluded residual lithiasis. One month after patient discharge, EUS excluded stones recurrence.
Detective Flow Imaging vs Contrast-Enhanced Endoscopic Ultrasonography in solid pancreatic lesions
Authors: M. V. Mulqui, F. Caillol, J. P. Ratone, S. Hoibian, Y. Dahel, E. Meunier, C. Archimbaud, M. Giovannini
Journal: Endoscopy (2024)

Aims Detective flow imaging endoscopic ultrasonography (DFI-EUS) is a new technology that detects fine vessels and low-flow velocity without contrast agents, used in real time during EUS, with a better resolution compared to usual technologies such as color-Doppler and eFLOW. The aim of this study was to compare DFI-EUS with the technique of contrast-enhanced endoscopic ultrasonography (CE-EUS) for the evaluation of vascularization in solid pancreatic lesions.
Changes in Sleep Patterns, Genetic Susceptibility, and Incident Cardiovascular Disease in China
Authors: Tingyue Diao, Kang Liu, Junrui Lyu, Lue Zhou, Yu Yuan, Handong Yang, Tangchun Wu, Xiaomin Zhang
Journal: JAMA Network Open (2024)

Importance The associations of changes in sleep patterns with incident cardiovascular disease (CVD) are not fully elucidated, and whether these associations are modified by genetic susceptibility remains unknown. Objectives To investigate the associations of 5-year changes in sleep patterns with incident CVD and whether genetic susceptibility modifies these associations. Design, Setting, and Participants This prospective cohort study of the Dongfeng-Tongji cohort was conducted from 2008 to 2018 in China. Eligible participants included those with complete sleep information at baseline survey (2008-2010) and the first follow-up survey (2013); participants who had no CVD or cancer in 2013 were prospectively assessed until 2018. Statistical analysis was performed in November 2023. Exposures Five-year changes in sleep patterns (determined by bedtime, sleep duration, sleep quality, and midday napping) between 2008 and 2013, and polygenic risk scores (PRS) for coronary heart disease (CHD) and stroke. Main Outcomes and Measures Incident CVD, CHD, and stroke were identified from 2013 to 2018. Cox proportional hazards regression models were applied to estimate hazard ratios (HRs) and 95% CIs. Results Among 15 306 individuals (mean [SD] age, 65.8 [7.4] years; 8858 [57.9%] female and 6448 male [42.1%]), 5474 (35.78%) had persistent unfavorable sleep patterns and 3946 (25.8%) had persistent favorable sleep patterns. A total of 3669 incident CVD cases were documented, including 2986 CHD cases and 683 stroke cases, over a mean (SD) follow-up of 4.9 (1.5) years. Compared with those with persistent unfavorable sleep patterns, individuals with persistent favorable sleep patterns over 5 years had lower risks of incident CVD (HR, 0.80; 95% CI, 0.73-0.87), CHD (HR, 0.84; 95% CI, 0.76-0.92), and stroke (HR, 0.66; 95% CI, 0.54-0.82) in the subsequent 5-year period. No significant effect modification by PRS was observed for sleep pattern change and CHD or stroke risk. However, sleep pattern changes and PRS were jointly associated with the CHD and stroke risk in a dose-dependent manner, with the lowest risk being among those with persistent favorable sleep patterns combined with low PRS (HR for CHD, 0.65; 95% CI, 0.52-0.82 and HR for stroke, 0.48; 95% CI, 0.29-0.79). Conclusions and Relevance In this cohort study of middle-aged and older Chinese adults, individuals with persistent favorable sleep patterns had a lower CVD risk, even among those with higher genetic risk. These findings highlight the importance of maintaining favorable sleep patterns for CVD prevention.
Giardia-Associated Duodenal Stricture
Authors: S. Malipatil, K. Khalaf, M.R. A. Fujiyoshi, N. Calo, J. Mosko, C. Teshima, G. May, S. Grover
Journal: Endoscopy (2024)

Abstract Text A 71-year-old male was diagnosed with common variable immunodeficiency (CVID) on immunoglobulin therapy.For several years he had mild intermittent chronic diarrhea.HIV,HLADQ2/DQ8, stool culture and Clostridoides difficile testing were negative.The second part of the duodenum revealed circumferential ulceration and cicatrization of the mucosa.Histopathology confirmed duodenal mucosa with subtotal villous blunting, architectural distortion,and moderate to severe acute inflammation,with copious Giardia lamblia trophozoites present.Giardia duodenalis is a common infection in individuals with CVID that can be associated with chronic inflammation leading to the complication of duodenal strictures.
Expect the unexpected. Caustic injuries
Authors: C. Konstantakis, P. Mantzios, K. Letsas, C. Sotiropoulos, K. Thomopoulos
Journal: Endoscopy (2024)

Abstract Text A 21-year-old male with history of hemorrhoidal disease was hospitalized for acute onset bloody diarrhea. Patient was in excellent clinical condition. No marked findings on physical examination besides a positive (blood) digital rectal examination. Patient refused using any medication. Flexible sigmoidoscopy revealed diffuse marked edema, erythema, absent vascular pattern and superficial erosions of the mucosa up to the rectosigmoid junction with completely normal mucosa above this. Biopsies were obtained on suspicion of a Mayo 2 ulcerative colitis. However, after further inquiry patient divulged pouring hydrogen peroxide per rectal as ''a cleaning aid''. Following psychiatric evaluation, patient was managed conservatively. Caustic injury of the rectum is a rare event which can develop into a life – threatening condition. High suspicion index and good medical history in ''atypical'' cases can assist significantly in the diagnosis. [1] [2] [3] [4]
A Case of a Large Obstructing Pancreatic Stone Treated with Single-Operator Pancreatoscopy and Electrohydraulic Lithotripsy
Authors: E. Troncone, R. Amendola, A. Moscardelli, P. Santangelo, E. De Cristofaro, C. Petruzziello, P. De Vico, G. Monteleone, A. Anderloni, G. Del Vecchio Blanco
Journal: Endoscopy (2024)

Abstract Text Pancreatoscopy with lithotripsy has been proposed as an effective therapeutic strategy in patients with pancreatic stones. Here, we report a case of a 44-years-old female with clinical history of severe abdominal pain and radiological evidence of a 30 mm pancreatic stone in the cephalic portion of the main pancreatic duct (PD). Extracorporeal shock wave lithotripsy had been already attempted, without success, and surgery had been proposed, that the patient refused. ERCP with single-operator pancreatoscopy and electrohydraulic lithotripsy was performed, with complete fragmentation of the stone and extraction of the fragments. Two plastic stents were placed at the end of the procedure, and the patient was discharged without adverse events. Two months later, a second ERCP demonstrated complete clearance of the stone and fragments. The plastic stents were replaced to ensure pancreatic drainage.
Hemostatic powder versus conventional treatments for malignancy-related upper gastrointestinal bleeding
Authors: J. H. Yoon, D. H. Jung, C. W. Huh, J. C. Park, S. K. Shin, S. K. Lee, Y. C. Lee
Journal: Endoscopy (2024)

Aims Endoscopic hemostasis is considered as 1st-line treatment of malignancy related gastrointestinal (GI) bleeding. Despite advances in endoscopic treatments, malignancy related GI bleeding is hard to manage with high rates of treatment failure and rebleeding. Recently, hemostatic powder (HP) has been used to treat malignancy related GI bleeding. Its adhesive and cohesive property fascilitates coagulation cascade, and it can be easily sprayed to the large surface of tumor bleeding with non-contact application. However, there are few reports about the efficacy of HP for malignancy-related upper GI bleeding (UGIB). Therefore, we aimed to assess the efficacy of HP compared with conventional treatments in terms of initial hemostasis and rebleeding rates for malignancy-related UGIB.
Patients’ sentiments on artificial intelligence in endoscopy: A large-scale intercontinental opinion survey
Authors: J. De Groof, O. Ahmad, M. Engels, S. A. Hoogenboom, N. Coelho-Prabhu, H. Yu, M. Mwachiro, S. Parasa, R. Mansilla, J. Mushtaq, H. Neumann, S. Thakkar, M. Byrne, J. van Hooft, Y. Tomonori, M. Yuichi
Journal: Endoscopy (2024)

Aims In recent years, the number of clinical studies evaluating artificial intelligence (AI) systems in endoscopy has increased. Authorities encourage integration of patients' thoughts in development of innovative medical interventions to allow their patient-friendly implementation. However, little is known about patient perception regarding AI in endoscopy.
Early Surgery After Hospitalization with Penetrating Crohn’s Disease Reduces Adverse Sequelae compared to Conservative Treatment
Authors: R. Tzadok, T. Thurm, P. N. Nachmias, H. Leibovich, A. Hirsch, Y. Ron, N. Maharshak
Journal: Endoscopy (2024)

Aims Early surgical intervention in Crohn's disease (CD) with inflammatory (B1) phenotype has been shown to be equally successful compared to biologic treatment in the LIR!C study. On the other hand, the prospective multicenter CREOLE study demonstrated long term (>4 years) surgery free survival in stricturing (B2) CD in over 50% of patients, treated with medical and endoscopic therapy. This work was aimed to compare long term outcomes between the early surgery and conservative treatment approach in patients presenting with penetrating (B3) CD.
Navigating Ulcerative Colitis Knowledge on YouTube: A Critical Assessment of Academic and Anecdotal Sources
Authors: R. M. Ram Mohan, M. Joy, D. Natt, S. G. Magam, S. R. Magam, L. Pannikodu, J. Desai, P. Mustacchia
Journal: Endoscopy (2024)

Aims This study examines the varying impact of YouTube videos on Ulcerative Colitis (UC) from academic and private institutions. While academic channels offer evidence-based, scientifically vetted information, private sources may lack rigorous scrutiny and sometimes prioritize commercial or anecdotal content. With YouTube's massive user base, the absence of an editorial process can result in misinformation. This content quality and credibility discrepancy can significantly affect patient education and treatment outcomes for UC.
Endoscopic submucosal dissection at a high-level center in the Tenerife south healthcare area. Our experience since 2016
Authors: C. Iglesias Sobrino, E. Suarez Zambrano, M. De Bonis Encinoso, H. A. Rodriguez Santos, S. Acosta Lopez, P. Borque Barrera, D. García Romero, S. Morales González, A. Amoros Tenorio
Journal: Endoscopy (2024)

Aims Endoscopic Submucosal Dissection (ESD) is the first treatment option for preneoplastic lesions and neoplasms with low risk of lymphatic invasion in the gastrointestinal tract, providing a less invasive alternative to conventional surgery.The purpose of the study was to evaluate the outcomes of patients undergoing ESD in our unit since the implementation of this endoscopic technique in 2016.Our main objective was to analyze the safety and effectiveness of the ESD technique in our center. Our secondary objective was to perform a comparative assessment of the technique over two time periods.
An unusual case of pancreatic cyst
Authors: A. Mauriello, S. Gaia, F. Fimiano, M. T. Staiano, E. Dall'Amico, M. Sacco, C. De Angelis
Journal: Endoscopy (2024)

Abstract Text 64 yo man has a clinical history of cirrhosis. An abdominal US follow-up and a subsequent CT scan diagnosed cholelithiasis, two big pancreatic cysts, and thickening of the colon wall, with multiple mesenteric lymphnodes. A colonoscopy and biopsies revealed a signet-ring cell colon carcinoma(CCR). Laparoscopic cholecystectomy, segmental colon resection, and removal of multiple mesenteric lymph nodes were performed and adjuvant CH was started. To study the pancreatic cysts, a pEUS with FNA and Micro-forceps was performed. Histopathology confirmed the presence of mucus with signet-ring adenocarcinoma cells inside the body cyst, and amorphous and biliary material, along with numerous histiocytes inside the tail cyst. With all these findings, a diagnosis of pancreatic tail pseudocyst and a rare case of pancreatic body metastasis of signet-ring cell CCR was established. [1]
Iron deficiency anemia in young women: is colonoscopy mandatory for etiological assessment in the absence of alarm signs?
Authors: S. Zaouga, S. Hamouda, M. Abdelawahed, I. Jemni, N. Ben Chaabane, L. Safer
Journal: Endoscopy (2024)

Aims The etiological diagnosis of iron deficiency anemia in young women, in the absence of an obvious gynecological cause, necessitates the exclusion of neoplastic or benign pathologies of the digestive tract. Colonoscopy is one of the investigations in the etiological assessment.