POS0439-HPR PATTERN OF LIFESTYLE HABITS IN PATIENTS WITH RHEUMATOID ARTHRITIS
Authors: M. L. Karlsson, L. Klareskog, D. DI Giuseppe, K. Chatzidionysiou
Journal: Annals of the Rheumatic Diseases (2024)

<h3>Background:</h3> Background: Adopting healthy lifestyle habits should be an important part of Rheumatoid Arthritis (RA) management [1], since it can lead to more favourable outcomes and decrease the risk of comorbidities [2]. <h3>Objectives:</h3> To investigate the patterns of healthy lifestyle habits (HLH) at the time of RA diagnosis and three years later, as well as the proportion of patients who adopt HLH after RA diagnosis. <h3>Methods:</h3> Patients with newly diagnosed RA were asked to participate in the Swedish epidemiological investigation of RA (EIRA), a longitudinal, epidemiological case-control study investigating risk factors for developing RA. We assessed, physical activity, smoking and alcohol consumption. Physical activity was divided into four categories 1) &lt; 120 m/w (week) on moderate level, 2) &gt; 120 min/w on moderate level, 3) 30-90 m/w on a high level, 4) &gt;90 min/w on high level. Participants in categories &gt; 2 were considered to have a healthy physical activity. Positive change (PC) was defined as change to a higher category. Smoking status was defined as current, former or never smokers. PC was defined as smoking cessation or decreased number of cigarettes per day by ≥50%. Alcohol consumption under 120 g/w was considered as healthy alcohol habit. PC was defined as decreased consumption by ≥50%. <h3>Results:</h3> A total of 1097 participants had participated at baseline and year three. The majority 798 (73%) were female, 683 (63%) were positive for Rheumatoid Factor (RF) and 733 (67%) were positive for anti-citrullinated peptide antibodies (ACPA). The men age was 55.6 years (SD=13). At baseline 253 (23%) of the patients were current smokers, and 158 (14%) reported unhealthy alcohol habits, while at year three, current smokers were 182 (17%) and 32 (3%) had unhealthy alcohol habit. At baseline 177 (16%) had a physical activity &lt;120 min/w on a moderate level which percentage increased to 29% at year three (see Table 1). Over 50% of patients reported three HLH at time for diagnosis and preserved them at year three. The majority of the participants did not change their number of HLH but there were groups of participants with increased and decreased number of HLH (Figure 1 and Table 1). Between baseline and year three 40% had made PC in smoking behaviour and 414 (45 %) had PC in alcohol consumption. In the subgroup or participants which had unhealthy alcohol consumption at baseline (n=158), 115 (76 %) had made positive change. Regarding physical activity, 435 (40%) had made PC and among the subgroup of patient which had unhealthy physical activity at baseline (n=177), 97 (55%) hades mad a PC to year three. <h3>Conclusion:</h3> In this study half of the RA participants already had three HLH at the time of diagnosis which most of them maintained even 3 years after diagnosis. Interestingly, patients who had no or maximum one HLH improved the most after RA diagnosis regarding their lifestyle habits. <h3>REFERENCES:</h3> [1] van Halm VP, Peters MJ, Voskuyl AE, Boers M, Lems WF, Visser M, et al. Rheumatoid arthritis versus diabetes as a risk factor for cardiovascular disease: a cross-sectional study, the CARRE Investigation. Ann Rheum Dis. 2009;68(9):1395-400. [2] Gwinnutt JM, Wieczorek M, Balanescu A, Bischoff-Ferrari HA, Boonen A, Cavalli G, et al. 2021 EULAR recommendations regarding lifestyle behaviours and work participation to prevent progression of rheumatic and musculoskeletal diseases. Annals of the rheumatic diseases. 2022. <h3>Acknowledgements:</h3> This abstract is on behalf of EIRA group. <h3>Disclosure of Interests:</h3> Marie-Louise Karlsson Novartis, Novartis, Lars Klareskog: None declared, Daniela Di Giuseppe: None declared, Katerina Chatzidionysiou Eli Lilly, Abbvie, Pfizer, Galapagoz.