MYXEDEMA AND DIABETES MELLITUS: A CASE REPORT WITH AUTOPSY FINDINGS
Authors: J. B. Carey, S. Lane Arey, E. H. Norris
Journal: Annals of Internal Medicine (1937)

Case Reports1 November 1937MYXEDEMA AND DIABETES MELLITUS: A CASE REPORT WITH AUTOPSY FINDINGSJ. B. CAREY, M.D., F.A.C.P., S. LANE AREY, M.D., E. H. NORRIS, M.D.J. B. CAREY, M.D., F.A.C.P.Search for more papers by this author, S. LANE AREY, M.D.Search for more papers by this author, E. H. NORRIS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-5-838 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe patient reported in 19301 as having the rare combination of myxedema and diabetes died in November 1936 of carcinoma of the bowel. An autopsy was done and the complete report of the case is herewith presented (summarized in table 2).The number of cases in the literature is not large. Shepardson and Wever9and Weinstein10have recently added to the series and in so doing have sufficiently surveyed the literature and the subject in general. One additional case (Castex et al.) has been reported since their article appeared and a summary of the total series is given in table...Bibliography1. CAREY JB: A case of myxedema and diabetes, Minn. Med., 1930, xiii, 578. Google Scholar2. FRITZ R: Relation of hyperthyroidism to diabetes, Arch. Int. Med., 1921, xxvii, 305. CrossrefGoogle Scholar3. GARDINER-HILLBRETTSMITH HPCJF: Carbohydrate tolerance in myxedema, Quart. Jr. Med., 1925, xviii, 327-334. CrossrefGoogle Scholar4. GRAY H: Blood sugar standards; normal and diabetic persons, Arch. Int. Med., 1923, xxxi, 241-258. CrossrefGoogle Scholar5. HOLST J: Glycosuria and diabetes in exophthalmic goiter, Acta. med. Scandinav., 1921, lv, 302. Google Scholar6. JAMIESON HC: Diabetes mellitus and myxedema, Canad. Med. Assoc. Jr., 1927, xvii, 88-89. Google Scholar7. JANNEYISAACSON NWVI: Blood sugar in endocrine diseases, Arch. Int. Med., 1923, xxxi, 241-258. Google Scholar8. SAINTON P: Les syndromes diabetiques associés aux syndromes endocriniens, Le Prog. Med., 1935, l, 2043. Google Scholar9. SHEPARDSONWEVER HCGK: Myxedema and diabetes, Internat. Clin., 1934, iv, 132. Google Scholar10. WEINSTEIN A: Diabetes mellitus and myxedema, Bull. Johns Hopkins Hosp., 1932, li, 27. Google Scholar11. WILDER RM: Hyperthyroidism, myxedema and diabetes, Arch. Int. Med., 1926, xxxviii, 736-760. CrossrefGoogle Scholar12. WRIGHT FR: Diabetes mellitus and myxedema: a report of two cases, Clifton Med. Bull., 1926, xii, 88. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Minneapolis, Minnesota*Received for publication February 15, 1937.From The Medical Department of The Nicollet Clinic, Minneapolis, and The Department of Pathology, Medical School, University of Minnesota, Minneapolis.†The cases reported by Gordon, Holst, Wright, Rohdenberg and one of Joslin's in 1928 are open to some question; that of Holst for instance was postoperative myxedema, not spontaneous; Gordon's cases were not well studied as to basal metabolic rate; and Wright's cases may have been only hypothyroid, although they seemed to have some of the symptoms of myxedema. One of Joslin's cases is of this same character, and in Rohdenberg's case the "diabetes" had disappeared before the onset of the myxedema. An autopsy done in this latter case showed atrophy of thyroid and hypertrophy of islands of Langerhans of the pancreas, but detailed studies of neither metabolic conditions were made during life. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byFATAL MYXEDEMA, WITH AND WITHOUT COMA*†JOHN F. NICKERSON, S. RICHARDSON HILL JR., M.D., JEAN H. MCNEIL, M.D., SAMUEL B. BARKER, Ph.D.Krankheiten der Schilddrüse 1 November 1937Volume 11, Issue 5Page: 838-845KeywordsAtrophyAutopsyDiabetes mellitusPancreasThyroid ePublished: 1 December 2008 Issue Published: 1 November 1937 PDF downloadLoading ...