tbuckley/cabot-search huggingface dataset:
Digestive involvement during adult rheumatoid purpura: about 38 cases
Authors: L. Khayat, R. Jmai, E. Souilem
Journal: Endoscopy (2024)

Aims Rheumatoid purpura is a systemic vacuities of small vessels with immunoglobulin A (IGA) deposits, characterized by the association of cutaneous vascular purpura with articular, gastrointestinal signs that can occur in bouts. Renal involvement is sometimes associated with these signs. The prognosis of the disease in the short term depends on the severity of the digestive involvement and in the long term of the renal involvement.
ESD for proximal colonic lesions: a safe and effective therapeutic option
Authors: A. Repici, A. Capogreco, R. Maselli, E. Mastrorocco, D. Massimi, F. Minini, R. de Sire, L. Alfarone, A. Galtieri, A. Facciorusso, C. Hassan
Journal: Endoscopy (2024)

Aims Endoscopic submucosal dissection (ESD) is the standard of treatment for rectal lesions due to the high risk of submucosal invasion. On the other hand, for proximal lesions is not widely adopted due to the very low risk of submucosal invasion and the technical challenges of the approach. Aim of our study was to assess technical and clinical outcome of patients treated by ESD for lesions located proximally to the splenic flexure.
Is the periampullary diverticulum a failure factor of cannulation during endoscopic retrograde cholangiopancreatography for choledocolithiasis?
Authors: T. Addajou, S. Mrabti, A. Benhamdane, R. Berraida, I. Elkoti, R. Fedoua, S. Hassan
Journal: Endoscopy (2024)

Aims A periampullary diverticulum (PAD) is defined as a duodenal depressed lesion of more than 5 mm with an intact mucosa within a radius of 2.5 cm of the major papilla. Presence of PAD is thought to complicate endoscopic retrograde cholangiopancreatography (ERCP).
Endoscopic fluoroscopy-guided rendezvous recanalization of a complete colorectal anastomotic stricture with a lumen-apposing metal stent
Authors: D. Arese, M. A. La Terra, G. Giudici, M. Spandre, F. Frigo, F. Coppola
Journal: Endoscopy (2024)

Aims Colorectal anastomotic strictures affect up to 30% of patients submitted to colo-rectal cancer surgery. However, a complete obstruction is rare. To prevent a surgical revision of the anastomosis, an endoscopic mini-invasive approach may be proposed, but the successful outcome depends on the possibility to pass a guidewire, followed by dilation or placement of a stent through the stricture. In patients with a colostomy if it's not possibile to overcome the stricture, the passage of a guide-wire can be perfomed under echoendoscopic guidance or under direct endoscopic guidance favoured by transillumination through the colonic wall as a reference. The difference between the two methods consists in the filling of the colonic loop in case of echo-endoscopy, or in a simultaneous dual endoscopic procedure in case of transillumination.
Participation rate of the target population in colorectal cancer screening – results from the evaluation of the National Colorectal Cancer Screening Program in the Czech Republic
Authors: T. Grega, O. Ngo, M. Ambrozova, K. Hejcmanova, R. Chloupkova, O. Majek, M. Zavoral, S. Suchanek
Journal: Endoscopy (2024)

Aims The National Colorectal Cancer (CRC) Screening Program was launched in the Czech Republic in 2000 as an opportunistic screening program. In 2014, this program was transformed into a population-based program by introducing an address invitation of the target population. This led to a significant increase in the participation rate of the target population in CRC screening. Due to the covid pandemic, overall participation significantly dropped during years 2020 and 2021. The main aim of the study was to evaluate the level of participation of the target population in the CRC screening program. Other objectives included evaluating the effectiveness of screening tests (FOBT, screening colonoscopy, FOBT-positive colonoscopy).
Investigating Occult GI Bleeds with Small bowel Capsule Endoscopy; what have we learnt?
Authors: B. A. Ogon, C. Walker, C. Goulding
Journal: Endoscopy (2024)

Aims To assess the incidence of significant findings on SBCE; co-relate them with the haemoglobin levels, the use of antiplatelets/anticoagulant and the use of non-steroidal anti-inflammatory drugs in patients referred with OGIB.
Evaluation of efficiency and safety profile of colon lesions resection using endoscopic submucosal dissection (ESD) – single operator experience in non-academic center
Authors: J. Drzewiecki, M. Jagielski, M. Jackowski
Journal: Endoscopy (2024)

Aims ESD is a prominent technique for colorectal lesion resection in Asian countries. There is not enough data on results of ESD treatment in Europe. The aim of this study is efficiency and safety profile analysis of a large group of patients with colorectal lesions resected by the ESD method in a non – academic center in Poland
Complicated Barrett’s Lesions and Subsequent Endoscopic Eradication Therapy: A Single Centre Irish Experience
Authors: A. Lloyd, C. Moran, C. Mcdonald, T. Murphy
Journal: Endoscopy (2024)

Aims Endoscopic eradication therapy (EET), combining endoscopic mucosal resection (EMR)/submucosal dissection (ESD) with ablation, is the preferred treatment for complex Barrett's lesions, aiding diagnosis, staging and potential eradication of mucosal dysplasia/neoplasia. ESD offers lateral margin data but has associated procedure risks. EMR demonstrates comparable EET efficacy to ESD with an increased safety profile. We aim to review deep margin clearance post EMR for Barrett's related lesions and subsequent histological clearance post EET.
Antithrombotic therapy depicts a distinct small bowel bleeding clinical pattern: a retrospective cohort study
Authors: C. Marmo, D. Feliciani, R. Pola, E. Gaetani, G. Costamagna, A. Gasbarrini, M. E. Riccioni
Journal: Endoscopy (2024)

Aims The study aims to evaluate the diagnostic yield of small bowel capsule endoscopy in patients while on antithrombotic therapy for suspected small bowel bleeding.
Techniques of polypectomy of diminutive polyps: a real-life experience of a tertiary center
Authors: C. Stornello, M. Franco, S. Grillo, G. Peserico, A. Fantin
Journal: Endoscopy (2024)

Aims ESGE recommends cold snare polypectomy (CSP) as the preferred technique for removal of diminutive polyps (size≤5 mm) of the colon and rectum. In recent years, CSP has been increasingly used for small polyps instead of hot snare polypectomy (HSP). Histological analyses suggest that CSP causes less damage to blood vessels in the submucosal layers, which results in a reduced incidence of hemorrhage compared to HSP. The use of CSP has significantly increased over time, recent studies show that now it accounts for 2/3 of all polypectomies for<6 mm polyps. Results from a recent network meta-analysis show that CSP is safer than HSP for<10 mm polyps, especially for patients taking anti-thrombotic drugs. We therefore aim to evaluate the resection attitude in a tertiary center that is not included by the colorectal cancer screening campaign.
Assessing the Frequency of Type I Gastric Neuroendocrine Neoplasms in Autoimmune Atrophic Gastritis: A Multi-Center Study in Italy
Authors: S. Massironi, C. Gallo, E. Lahner, V. Sciola, F. Cavalcoli, M. V. Lenti, E. Miceli, A. Zilli, L. Dottori, G. De Rossi, B. Annibale, M. Vecchi, P. Cantù, A. Di Sabatino, P. Invernizzi, S. Danese
Journal: Endoscopy (2024)

Aims In autoimmune atrophic gastritis (AAG), immune-mediated morpho-functional changes in gastric mucosa lead to hypo-achlorhydria and subsequent hypergastrinemia. This stimulates gastric enterochromaffin-like (ECL) cell proliferation, escalating the risk of type I gastric neuroendocrine neoplasms (gNENs). Yet, longitudinal studies on the AAG-type I gNENs association are still scanty. Our study aims to assess the frequency of type I gNENs in patients with AAG, evaluated at six tertiary referral centers in Italy.
Performance of the modified Kyoto classification for prediction of Helicobacter pylori infection
Authors: S. Hafi, G. Mohamed, A. Mnif, K. Boughoula, S. Bizid, H. Ben Abdallah, R. Bouali, M. N. Abdelli
Journal: Endoscopy (2024)

Aims The modified Kyoto classification is a score allowing a standardized and quantitative description of the different elementary gastric lesions. This score is validated for the prediction of Helicobacter pylori (Hp) current infection. The aim of this study was to evaluate the performance of the modified Kyoto classification for predicting Hp infection during endoscopy.
Application of Natural Orifice Transluminal Endoscopic Surgery with Endograsp System for Stomach Perforation Model: Ex-vivo porcine study
Authors: H. J. Jeon, T. J. Yoon, B. Lee, Y. Jiyoung, S. Kim, S. C. Hyuk, S. K. Eun, B. Keum, J. C. Hoon
Journal: Endoscopy (2024)

Aims Gastrointestinal tract perforation has become more common due to the rise of endoscopy, with a high mortality rate. Numerous closure methods have been devised for natural orifice transluminal endoscopic surgery, including Through-the-Scope Clip (TTSC) and Overstitch system, offering promise but also limitations. The current study aims to compare the feasibility and effectiveness of mucosal-submucosal suturing using a newly designed suture device with TTSC and manual suturing in an ex-vivo stomach wall perforation model.
Assessing the Impact of Fentanyl on Hypoxemia Risk in Upper Gastrointestinal Endoscopy: A Comparative Analysis
Authors: E. Klang, K. Sharif, N. Rahman, A. Lahat
Journal: Endoscopy (2024)

Aims Sedation plays a pivotal role in ensuring patient comfort and procedure efficacy during upper GI endoscopy. However, the choice of sedative agents is a delicate balance between achieving adequate sedation and minimizing adverse events, particularly hypoxemia. Currently, there are few commonly used sedation protocols. This research aims to compare hypoxemia risk between 2 commonly used protocols.
Severe oesophageal hyperkeratosis: A case series
Authors: A. Vella Baldacchino, J. Kelly, E. Jaynes, I. Rahman, P. Patel, P. Boger
Journal: Endoscopy (2024)

Aims To present a case series of severe, diffuse oesophageal hyperkeratosis and emphasise the strong association of this condition with underlying oesophageal squamous cell carcinoma (SCC).
The long term efficacy of argon plasma coagulation (APC) ablation of oesophageal inlet patch in patients with globus symptoms
Authors: W. Mostafa, S. Hebbar
Journal: Endoscopy (2024)

Aims The oesophageal inlet patch is an area of heterotopic gastric mucosa at or just distal to the upper oesophageal sphincter. This can be symptomatic and lead to dysphagia, chronic globus sensation and or reflux symptoms. We aimed to determine the long term effects of argon plasma coagulation (APC) ablation of oesophageal inlet patch in patients with globus symptoms.
Should upper gastrointestinal endoscopy be systematically performed in patients with Inflammatory Bowel Disease ?
Authors: H. Koulali, A. Zazour, O. Elmqaddem, Z. Ismaili, K. Ghizlane
Journal: Endoscopy (2024)

Aims Understanding the extent of Inflammatory Bowel Disease (IBD) is fundamental for optimal management, while Crohn's disease (CD) can affect all the gastro-intestinal tract, ulcerative colitis is localized in the rectum and colon. This study investigates the potential utility of systemic gastroscopy in IBD patients.
Results and associated factors of endoscopic treatment of large bile duct stones and choledocholithiasis
Authors: I. Mouslim, R. Chaibi, A. Benhamdane, T. Addajou, S. Mrabti, R. Berraida, I. Elkoti, R. Fedoua, S. Hassan
Journal: Endoscopy (2024)

Aims Endoscopic biliary sphincterotomy is effective in treating choledocholithiasis. However, its results can be limited by the presence of gallstones. Our work aims to evaluate the effectiveness of endoscopic retrograde cholangiopancreatography (ERCP) in patients with a large obstructive gallstone measuring more than 15mm and patients with a choledochal entrapment. This can lead us to identify the factors influencing endoscopic drainage as well as its complications in the management of large bile duct stones.
Examining the certainty of optical diagnoses for colonic polyps at a Reference Center in Latin America
Authors: L. A. Revuelta, R. Barreto-Zuniga, L. C. Chavez, E. Barreda, M. Pacheco
Journal: Endoscopy (2024)

Aims The certainty in the optical diagnosis of small polyps less than 10 mm without histological analysis can make colonoscopy more efficient and cost-effective. To implement this strategy, European guidelines recommend an optical-histological certainty greater than 90% (sensitivity greater than 90% for adenoma detection and specificity greater than 90% for hyperplastic polyp detection). This study aimed to assess the optical-histological certainty of colonic polyps among trainee endoscopists at a Reference Center in Latin America.
A Second Colonoscope Help to Release an Incarcerated Colonoscope during Colonoscopy: an Effective New Method Report
Authors: T. Qiuyue, Z. Huixia, B. Liu
Journal: Endoscopy (2024)

Abstract Text A 61-year-old man was receiving colonoscopy, however, colonoscope could not be advanced or withdrawn at approximately 70 cm. Then, the endoscopist was informed that the patient had an inguinal hernia. Incarceration of colonoscope was suspected. The patient was transferred to the fluoroscopy room immediately.Under fluoroscopy, a loop of colonoscope was seen in the hernia. The colonoscope could not be withdrawn directly while the loop of the scope within the hernia sac was in α−shape or a U-shape, because traction on the scope resulted in straightening the proximally created loops first. An alternative technique of removal was used successfully. At the proximally created loops first, we introduced second colonoscope as a pulley. Then, the incarcerated colonoscope was slowly and smoothly withdrawn without incident. [1] [2] [3]
Long-term outcomes of endoscopic ultrasound-guided pancreatic duct interventions: a single tertiary-care center experience
Authors: J. B. Gornals, A. Sumalla-Garcia, D. Luna-Rodriguez, M. Puigcerver-Mas, J. Velasquez-Rodriguez, S. Salord, J. Escuer, S. Maisterra, J. Busquets
Journal: Endoscopy (2024)

Aims Endoscopic ultrasound-guided pancreatic duct intervention (EUS-PDI) is one of the most technically challenging procedures. There remains a knowledge gap due to its rarity. The aim is to report the accumulated EUS-PDI experience in a tertiary center.
Gastric plasmacytoma as a rare cause of abdominal pain
Authors: E. Tettoni, A. Fraghì, S. M. Milluzzo, P. Cesaro
Journal: Endoscopy (2024)

Abstract Text A 60 year-old man was admitted to our hospital due to lasting pain localized in upper abdominal quadrants. CT scan revealed plurinodular thickening of the gastric body and fundus. EGD confirmed the presence of multiple submucosal nodules at esophageal, gastric, and duodenal levels. Histological analysis identified the presence of plasma cell myeloma with high proliferative index. Plasmacytoma is defined as extra-skeletal accumulations of monoclonal plasma cells. GI tract is rarely involved and the small bowel is the most frequently affected segment. Patients with gastric plasmacytoma typically exhibit nonspecific symptoms like epigastric pain, weight loss, and upper GI bleeding. The endoscopic appearance of plasmacytomas varies considerably but may resemble other more common conditions, including poorly differentiated or metastatic neoplasms, MALT lymphoma, and GI amyloidosis.
Colon cancer among different ethnic groups, population-based large cohort of two ethnic groups
Authors: N. Abu-Freha, W. Alamor, O. Alamour, H. Abu Kaf, M. Aasla, B. Yousef, J. Elkrinawi
Journal: Endoscopy (2024)

Aims We aimed to investigate the general characteristic, comorbidities, and all cause-mortality of CRC among the Arab population compared to the Jewish population.
Endoscopic ultrasound-guided radiofrequency ablation of pancreatic tumors- initial experience of single center
Authors: Y. Petkova, P. Karagyozov, N. Shumka
Journal: Endoscopy (2024)

Aims The mainstay treatment for pancreatic tumors is surgery. However adverse events and post -operative mortality are a concerning issue. Endoscopic ultrasound-guided radiofrequency ablation/EUS RFA/ is a novel technique for local destruction, applicable for pancreatic neuroendocrine tumors /PanNEN/, locally advanced adenocarcinoma and cystic pancreatic neoplasms.Our aim was to evaluate the technique in terms of efficacy and safety. Primary endpoint was complete response rate defined as disappearance of lesions or no signs of vital tissue on imaging studies during follow up. The secondary endpoint was the assessment of adverse events/AE/ associated with the procedure.
Molecular profiles of malignant colorectal polyps within the European Polyp Surveillance Study (EPOS IV)
Authors: W. Korcz, A. Mroz, M. Szmit, J. A. Nilsen, G. Antonelli, M. Bretthauer, J. Krzyżkowiak, Z. Orzeszko, P. Spychalski, J. Kobiela, N. D. Pilonis, M. F. Kaminski
Journal: Endoscopy (2024)

Aims To assess the risk of recurrence and metastasis following endoscopic or surgical treatment of pT1 colorectal cancer (CRC), as well as the necessity for invasive surgical treatment, utilizing conventional and novel histological molecular markers.
Colonoscopy findings in patients with a positive FIT (Fecal Immunochemical Test)
Authors: L. C. Chavez, J. A. Ruiz, E. Jasso Baltazar, C. Zubia, J. C. Ticona, A. Saul
Journal: Endoscopy (2024)

Aims Fecal Immunochemical Test (FIT) is increasingly recognized as an effective and practical colorectal cancer (CRC) screening tool, more cost-effective than colonoscopy, making it a suitable option for resource-limited settings. Ensuring that individuals with positive FIT results have timely access to follow-up colonoscopy is a significant challenge. This study aims to describe the most common findings in colonoscopy among patients with a positive fecal immunochemical test (FIT).
The proteomic analysis of gastric cancer cell line exosome for searching potential biomarkers
Authors: M. W. Lee, G. H. Kim, H. K. Jeon, D. C. Joo, D. J. Jung, B. E. Lee, G. A. Song
Journal: Endoscopy (2024)

Aims Exosome is small extracellular vesicles released from cancer cells, known to contain various materials associated with cancer development and progression. This study aimed to identify useful biomarkers for gastric cancer using proteomics analysis of gastric cancer exosomes.
Use of TC-325 hemostatic powder for bleeding upper gastrointestinal malignancy – From bridge therapy to palliative management. Video case series of different scenarios
Authors: C. Konstantakis, C. Sotiropoulos, G. Skroubis, G. Geramoutsos, T. Kafentzi, N. Kimiskidis, C. Triantos, K. Thomopoulos
Journal: Endoscopy (2024)

Abstract Text Recent literature supports use of TC-325 hemostatic powder in the management of malignant gastrointestinal (gi) bleeding. We present 3 cases with successful bleeding control: Patient 1: female 68y ECOG 1, linitis plastica. Bridge hemostasis. Patient was successfully referred for urgent radiotherapy. Patient 2: female 54y ECOG 4 with metastatic poorly differentiated adenocarcinoma of the stomach. Died 4 days later of disease complications. Palliative therapy. Patient 3: male 86, ECOG 2, metastatic adenocarcinoma. Failure of standard endoscopic treatment. Rescue therapy.Use of TC-325 can be used to provide (lasting) hemostasis in cases of upper gi malignancy. Besides palliation benefits, it can significantly improve transfusion needs resulting in improvement of both quality of life and other long-term oncological outcomes. Furthermore, it can serve as bridge to more definitive treatment like radiotherapy or surgery. [1] [2] [3] [4]
EUS-Guided Fine-Needle-Biopsy of Solid Lesions Using a 22G Needle – One size fits all?
Authors: M. Mirchev, M. Peruhova, I. Boeva, V. Stoitsov
Journal: Endoscopy (2024)

Aims To analyze the capability of a 22G multi-blade three-prong needle to provide a reliable core tissue for histological analysis from solid abdominal and mediastinal tumors and to compare it in pancreatic versus non-pancreatic tumors.
Multicentric observational study for patients undergone to peroral endoscopic septotomy for symptomatic Zenker diverticulum: mid term results
Authors: G. grande, R. Conigliaro, H. Bertani, S. Cocca, F. Pigò, M. Lupo, F. Pianigiani, C. Calvanese, S. Russo, M. Marocchi, R. Sassatelli, P. Cecinato, M. Gottin
Journal: Endoscopy (2024)

Aims Peroral endoscopic septotomy (POES) is a recent and promising technique for the treatment of oesophageal Zenker's diverticulum. It differs from well described Z-POEM for the access to submucosal space made directly from the top of the diverticular septum. After muscular isolation, the myotomy is extended up to diverticular plane and 10-15 mm beyond, in the esophageal verge. Therefore, the mucosal access to the tunnel is closed using TTS clips.
Large experience of EUS-guided gastroentero-anastomosis (EUS-GEA) validating the drain-assisted technique: we are ready for benign indications
Authors: J. M. Gonzalez, G. Vanbiervliet, M. Gasmi, S. Ouazzani, M. Barthet
Journal: Endoscopy (2024)

Aims EUS guided GEA is a serious alternative to duodenal stenting and surgical GEA in malignant gastric outlet obstruction (GOO). Indeed, efficacy and reintervention rates are significantly better than stenting, whereas non inferiority was demonstrated compared to surgery, with faster recovering. That is why recent ESGE guidelines recommended EUS-GEA as an alternative for malignant obstruction. However, because of adverse events such as misdeployment with the direct technique, the EUS-GEA was contra-indicated to benign indications. We propose our experience with the evolution toward drain assisted technique (DA-EUSGEA) and the increasing of benign indications.
Underwater technique reduces intraprocedural pain in colorectal endoscopic submucosal dissection performed under conscious sedation
Authors: P. Cecinato, C. Sicuro, M. Lucarini, M. Costetti, F. Bassi, G. Barbara, R. Sassatelli
Journal: Endoscopy (2024)

Aims Endoscopic submucosal dissection (ESD) allows en-bloc and R0-resection of colorectal lesions with suspected limited submucosal invasion. Patients' discomfort could represent a significant challenge to deal with when performing colorectal ESD (c-ESD). Adequate pain control has a pivotal role for patients' safety and procedure success, especially when ESD is performed under conscious sedation. As far as we know, no data are available about predictive factors of discomfort and technical difficulty in c-ESD. Water assisted colonoscopy has become an established alternative technique to CO2-insufflation, able to decrease insertion pain, improve patients' tolerance and allow to complete a difficult colonoscopy. The aim of our study was to identify intraprocedural discomfort determinants during c-ESD.
Endoscopic removal of cocaine pellets is safe
Authors: A. Aboikoni, M. Wallyn, D. Louvel, T.T. N. Nguyen, A. Becar, M. Alogo A Nwatsok, M. Zappa
Journal: Endoscopy (2024)

Aims The study aims to prouve that digestive endoscopic removal of cocaine pellets is a safe method, without risk of rupture.
Factors Associated with Failure of Endoscopic Extraction of Main Bile Duct Lithiasis: A Tunisian Center’s experience
Authors: E. Souilem, L. Khayat, W. Dahmeni, N. Elleuch, A. Hammami, A. Ben Slama, A. Braham, H. Jaziri, M. Ksiaa
Journal: Endoscopy (2024)

Aims Conventional treatment of main bile duct (MBD) lithiasis typically involves endoscopic sphincterotomy (ES) followed by stone extraction using a balloon and/or Dormia basket, enabling clearance of the main bile duct in 85 to 95% of cases. Several risk factors have been identified as associated with the failure of MBD stone extraction. This study aims to identify these factors associated with such failure.