FUNDAMENTAL PRINCIPLES IN THE ADJUSTMENT REACTIONS OF THE ORGANISM TO ANOXIA
Authors: Ernst Gellhorn
Journal: Annals of Internal Medicine (1941)

Article1 March 1941FUNDAMENTAL PRINCIPLES IN THE ADJUSTMENT REACTIONS OF THE ORGANISM TO ANOXIAERNST GELLHORN, M.D., Ph.D.ERNST GELLHORN, M.D., Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-14-9-1518 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA study of the effects of anoxia on the human organism and on laboratory animals is of particular value to physiology and medicine because it lends itself well to demonstrating the interrelation of various organ systems in the body. This aspect of the problem will be stressed in the following discussions as well as some important clinical implications. Finally an attempt will be made to show which characteristics of the central nervous system are ultimately responsible for the adjustment reactions occurring in anoxia.It is well known that under the influence of anoxia as induced by the breathing of suitable...Bibliography1. BARCROFT J: Features in the architecture of physiological function, 1934, New York. Google Scholar2. BEHAGUEGARSAUXRICHET PFC: Modifications thermiques observées sur le lapin, soumis a la depression atmosphérique, Compt. rendu Soc. biol., 1927, xcvi, 766. Google Scholar2a. CHEVILLARDMAYER LA: Recherches sur l'influence de la tension d'oxygène sur les échanges; influence de la tension de l'oxygène contenu dans l'air inspiré sur les échanges gazeux de la souris, Ann. Physiol., 1935, xi, 225. Google Scholar3. CARLSONDARROWGELLHORN HBCWE: Physiological and pharmacological studies on the hypothalamus, Am. Jr. Physiol., 1940, cxxix, 329. Google Scholar4. COBBFREMONT-SMITH SF: The cerebral circulation. XVI. 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