tbuckley/cabot-search huggingface dataset:
OS-029-YI Spatial profiling of HBVand HDV infection in human liver samples
Authors: Maria Saez-Palma, Marc Buendia, Thais Leonel, Ester García-Pras, Ángela Sanzo-Machuca, Mario Acera, Anna Pocurull Aparicio, Sara Battistella, Maëlle Locatelli, Sergio Rodriguez-Tajes, Sarah Shalaby, Asunción Ojeda, Alba Díaz, Yilliam Fundora, Elisabetta Mereu, Azucena Salas, Xavier Forns, Sabela Lens, Sofía Pérez-del-Pulgar
Journal: Journal of Hepatology (2025)
OS-001-YI A palliative care approach for cirrhosis patient: feasibility and preliminary results from a prospective Danish multi-center study
Authors: Birgitte Jacobsen, Mette Lauridsen, Ane Soegaard Teisner, Marie Louise Hamberg, Nina Kimer, Malene Barfod O’Connell, Palle Bager, Janni Mendahl, Kristoffer Marsaa, Mai-Britt Guldin, Lea Ladegaard Grønkjar
Journal: Journal of Hepatology (2025)
WED-509 Decoding the dynamics: minimal detectable difference in non-invasive tests may exceed proposed thresholds for meaningful changes
Authors: Georg Semmler, Chunsen Wu, Katrine Lindvig, Lucie Simonis, Jan Embacher, Philipp Hruska, Peter Andersen, Lorenz Balcar, Mathias Jachs, Michael Trauner, Aleksander Krag, Thomas Reiberger, Thomas Scherzer, Mattias Mandorfer, Maja Thiele
Journal: Journal of Hepatology (2025)
SAT-406 Role of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in mortality reduction among patients with obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) cirrhosis: a global retrospective analysis
Authors: Varun Aitharaju, Humza Aamir-Khan, Jamile Wakim-Fleming
Journal: Journal of Hepatology (2025)
Combining chromosome conformation capture and exome sequencing for simultaneous detection of structural and single-nucleotide variants
Authors: Maria Gridina, Timofey Lagunov, Polina Belokopytova, Nikita Torgunakov, Miroslav Nuriddinov, Artem Nurislamov, Lyudmila P Nazarenko, Anna A Kashevarova, Maria E Lopatkina, Stanislav Vasilyev, Andrey Zuev, Elena O Belyaeva, Olga A Salyukova, Aleksandr D Cheremnykh, Natalia N Sukhanova, Marina E Minzhenkova, Zhanna G Markova, Nina A Demina, Yana Stepanchuk, Anna Khabarova, Alexandra Yan, Emil Valeev, Galina Koksharova, Elena V Grigor'eva, Natalia Kokh, Tatiana Lukjanova, Yulia Maximova, Elizaveta Musatova, Elena Shabanova, Andrey Kechin, Evgeniy Khrapov, Uliana Boyarskih, Oxana Ryzhkova, Maria Suntsova, Alina Matrosova, Mikhail Karoli, Andrey Manakhov, Maxim Filipenko, Evgeny Rogaev, Nadezhda V Shilova, Igor N Lebedev, Veniamin Fishman
Journal: Genome Medicine (2025)

Effective molecular diagnosis of congenital diseases hinges on comprehensive genomic analysis, traditionally reliant on various methodologies specific to each variant type-whole exome or genome sequencing for single nucleotide variants (SNVs), array CGH for copy-number variants (CNVs), and microscopy for structural variants (SVs). We introduce a novel, integrative approach combining exome sequencing with chromosome conformation capture, termed Exo-C. This method enables the concurrent identification of SNVs in clinically relevant genes and SVs across the genome and allows analysis of heterozygous and mosaic carriers. Enhanced with targeted long-read sequencing, Exo-C evolves into a cost-efficient solution capable of resolving complex SVs at base-pair accuracy. Applied to 66 human samples Exo-C achieved 100% recall and 73% precision in detecting chromosomal translocations and SNVs. We further benchmarked its performance for inversions and CNVs and demonstrated its utility in detecting mosaic SVs and resolving diagnostically challenging cases. Through several case studies, we demonstrate how Exo-C's multifaceted application can effectively uncover diverse causative variants and elucidate disease mechanisms in patients with rare disorders.
FRI-111 The role of immune cell composition potentially predicts response to atezolizumab plus bevacizumab in patients with advanced hepatocellular carcinoma
Authors: Jana Knorr-Klocke, Marlene Kohlhepp, Fabian Artusa, Frank Tacke, Tobias Puengel, Alexander Wree, Raphael Mohr
Journal: Journal of Hepatology (2025)
THU-406 Life-style factors of patients with metabolic dysfunctionassociated steatotic liver disease (MASLD) – data from the german SLD-registry
Authors: Andreas Geier, Monika Rau, Anita Pathil-Warth, Wolf Peter Hofmann, Yvonne Serfert, Manfred von der Ohe, Leopold Ludwig, Renate Heyne, Kerstin Stein, Thomas Berg, Peter Buggisch, Münevver Demir, Elke Roeb, Laura Buttler, Martin Kabelitz, Benjamin Maasoumy, Stefan Zeuzem, Heiner Wedemeyer, Jörn M. Schattenberg
Journal: Journal of Hepatology (2025)
COVID ALI/ARDS Survivors Have Persistently Elevated Serum GDF-15 and Lower 6-Minute Walk Distance Over 3 Years: A Time-Independent Longitudinal Modeling Approach
Authors: Z. Khan, A. Jones, S. Murphy, C. McGroder, C. Depender, Y. Wei, C.K. Garcia, M.R. Baldwin
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
WED-191 De novo decompensation and portal vein thrombosis are both linked to similar pathophysiologic alterations associated with advanced liver disease
Authors: Erica Villa, Rosina Maria Critelli, Davide Guido, Fabiola Milosa, Filippo Schepis, Marcello Bianchini, Dario Saltini, Grazia Serino, Antonio Piscopo, Gianluigi Giannelli
Journal: Journal of Hepatology (2025)
FRI-369-YI Lysine-specific demethylase 1 modulates hepatic lipid metabolism in metabolic dysfunction-associated steatotic liver disease
Authors: Hardik Makwana, Jie Wang, Xinlei Zhao, Hannah Eischeid-Scholz, Vangelis Kondylis, Mafalda Escobar, Olaf Utermoehlen, Reinhard Büttner, Margarete Odenthal
Journal: Journal of Hepatology (2025)
SAT-044-YI Dynamic hepatocyte adaptations in acute biliary hypertension: role of canalicular remodeling, mechanosensors activation and alternate bile transport
Authors: Himanshi Himanshi, Rajni Yadav, Aishwarya Bhatnagar, Vaibhav Tiwari, Tahseen Khan, Rajkumar Tulsawani, Savneet Kaur, Shiv Kumar Sarin, Dinesh Mani Tripathi
Journal: Journal of Hepatology (2025)
OS-099 Personalised prediction of the individual risk of liver-related complications in MASLD using the dynamics of non-invasive tests of liver fibrosis
Authors: Clemence Moreau, Marine Roux, Huapeng Lin, Hye Won Lee, Terry Cheuk-Fung Yip, Emmanuel Tsochatzis, Salvatore Petta, Elisabetta Bugianesi, Masato Yoneda, Ming-Hua Zheng, Hannes Hagström, José Luis Calleja Panero, George Boon Bee Goh, Wah-Kheong Chan, Rocio Gallego-Durán, Arun J. Sanyal, Victor de Ledinghen, Philip Newsome, Jiangao Fan, Laurent Castera, Michelle Lai, Céline Fournier-Poizat, Grace Lai-Hung Wong, Grazia Pennisi, Angelo Armandi, Atsushi Nakajima, Wen-Yue Liu, Ying Shang, Marc de Saint-Loup, Elba Llop Herrera, Kevin Kim Jun Teh, Carmen Lara-Romero, Amon Asgharpour, Sara Mahgoub, Sau-Wai Mandy Chan, Manuel Romero-Gómez, Seung Up Kim, Vincent Wai-Sun Wong, Jerome Boursier
Journal: Journal of Hepatology (2025)
WED-352 Human biliary atresia extra-hepatic cholangiocyte organoids: elevated ER and oxidative stress, altered drug metabolism, and modified cell-to-cell junction
Authors: Yara Hamody, Adi Har-Zahav, Keren Danan, Raanan Shamir, Irit Gat-Viks, Orith Waisbourd-Zinman
Journal: Journal of Hepatology (2025)
THU-518 Multi-displinary team initiation of GLP-1/GIP agonist Tirzepatide in patients with metabolic-dysfunction associated steatotic liver disease (MASLD): single-centre UK study
Authors: Rachel Halley, Callum Riley, Jill Johnson, Maria Round, Julian Yeh, Sheeba Khan, Alexander Boyd, Geoffrey Haydon, Samiul Mostafa, Philip Newsome, Matthew Armstrong
Journal: Journal of Hepatology (2025)
FRI-123 The dose of radiation absorbed by the tumorand the non-tumoral compartments does not impact peripheral immune markers after SIRT
Authors: Elisa Pinto, Macarena Rodriguez-Fraile, Anneris Cabrera, Lidia Sancho Rodriguez, Diana Llopiz, Maria Ruiz, Leyre Silva, Ana Matilla, Maria Varela, María Reig, Manuel de la Torre, Josepmaria Argemi, Sandra Hervás-Stubbs, Pablo Sarobe, Bruno Sangro
Journal: Journal of Hepatology (2025)
THU-080 Platelet-derived extracellular vesicles (PEVs) in hepatocellular carcinoma. Emerging diagnostic biomarkers
Authors: Ángela Rojas, Rocío Munoz-Hernández, Sheila Gato-Zambrano, Antonio Gil-Gómez, Vanessa García-Fernández, Rocío Gallego-Durán, Douglas Maya-Miles, Teresa Ferrer, Isabel Fernández-Lizaranzu, Javier Ampuero, Manuel Romero-Gómez
Journal: Journal of Hepatology (2025)
WED-036 The impact of cardio-metabolic risk factors on liver-related diseases and mortality after hepatitis C virus eradication: insights from a multi-center taiwanese cohort
Authors: Ming-Lung Yu, Pei-Chien Tsai, Chung-Feng Huang, Jee-Fu Huang, Chiayen Dai, Wan-Long Chuang
Journal: Journal of Hepatology (2025)
WED-132 Serologic and immunologic biomarkers for the identification of patients with hepatocellularcarcinomawith high tumour burden and poor survival
Authors: Marta Guariglia, Silvia Gaia, Francesca Saba, Emanuela Rolle, Maria Lorena Abate, Chiara Rosso, Angelo Armandi, Patrizia Carucci, Elisabetta Bugianesi, Gian Paolo Caviglia
Journal: Journal of Hepatology (2025)
WED-420 Prescreening with a novel machine learning model (LiverPRO) may improve trial enrollment efficiency in metabolic dysfunction-associated steatohepatitis (MASH): a retrospective analysis of the SYNERGY-NASH trial
Authors: Mark Hartman, Yu Chen, Katrine Prier Lindvig, Yuanyuan Tang, Abhi Malatpure, Maja Thiele, Aleksander Krag
Journal: Journal of Hepatology (2025)
WED-177-YI Cirrhotic cardiomyopathy in patients underwent transjugular intrahepatic portosystemic shunt (TIPS): clinical impact of the updated diagnostic criteria for diastolic dysfunction
Authors: Chiara Becchetti, Elena Motto, Giovanni Perricone, Francesca Bolis, Raffaella Viganò, Marcello Vangeli, Chiara Mazzarelli, Monica Cucco, Fosca Anna Luisa Quarti Trevano, Fabiane Barbosa, Angela Alfonsi, Francesco Morelli, Pietro Maria Brambillasca, Carmine Andriulo, Francesco Musca, Paride Di Marco, Antonio Gaetano Rampoldi, Luca Saverio Belli, Marco Solcia, Aldo Airoldi
Journal: Journal of Hepatology (2025)
FRI-471 Comparison of the effects of tenofovir alafenamide and entecavir on renal function and serum lipids in liver transplant recipients: a retrospective observational study
Authors: Hüseyin Döngelli, Nilay Danıs, Tarkan Ünek, Tufan Egeli, Cihan Agèalar, Mücahit Özbilgin, Hülya Ellidokuz, Mesut Akarsu
Journal: Journal of Hepatology (2025)
SAT-358 Dynamics and prognostic implications of splanchnic volumetry in patients withportosinusoidal vascular liver disorder
Authors: José Ferrusquía-Acosta, Damián Gil-Bello, Katharina Lampichler, Marta Vidal, Diana Fuertes, Lucie Simonis, Chengjian Wu, Yi Shen, Luo Xuefeng, Fatima Torres Gómez, Mariano José Parada-Blázquez, Alvaro Giráldez-Gallego, Ainhoa Sánchez-Lorenzo, Daniel Selva-Talón, Edilmar Alvarado-Tapias, Dario Saltini, Denise Squecco, Filippo Schepis, Héloise Giudicelli, Mathilde Wagner, Dominique Thabut, Marta García-Calonge, Elena Uceda-Andrés, Carmen Álvarez-Navascués, Ozgur Koc, Razvan Miclea, Esther Maderuelo, Elba Llop Herrera, Meritxell Casas, Mireia Miquel, Mercedes Vergara, Lorenz Balcar, Jordi Sánchez, Cristina Solé, Bernhard Scheiner
Journal: Journal of Hepatology (2025)
THU-101-YI Selective targeting of class I histone deacetylases with new derivatives of ursodeoxycholic acid as a novel treatment strategy for bile duct cancer
Authors: Francisco Javier Caballero-Camino, Noelia Pastor de los Toyos, Irene Olaizola, Ivan Rivilla, Amanda Guimaraes, Pedro Miguel Rodrigues, Luis Bujanda, Fernando Pedro Cossío, Jesus Maria Banales
Journal: Journal of Hepatology (2025)
SAT-023 Treatment of Hepatitis C in the over-80 s in the direct anti-viral therapy era: age is no barrier!
Authors: Peter Sandwith, Kosh Agarwal, Graham R Foster, Beatrice Emmanouil, Mark Gillyon-Powell, Specioza Nabiteeko, Georgia Threadgold, Julian Surey, Rachel Hill-Tout, Leila Reid, Stuart Smith, Paul Trembling, Douglas Macdonald, Dan Forton, Upkar Gill, Ashley Brown, Matthew Foxton
Journal: Journal of Hepatology (2025)
THU-180-YI Toll-like receptor 4 inhibition restores cytochrome C oxidase mitigating hyperammonemia-induced hepatocyte mitochondrial dysfunction
Authors: Supachaya Sriphoosanaphan, Annarein Kerbert, Francesco de Chiara, Abeba Habtesion, Fausto Andreola, Gautam Mehta, Jan-Willem Taanman, Rajiv Jalan
Journal: Journal of Hepatology (2025)
TOP-002-YI Disparities in hepatocellular carcinoma screening and in its detection rates in individuals with hepatitis B or C and cirrhosis in Canada
Authors: Jean Damascene Makuza, Stanley Wong, Dahn Jeong, Richard Morrow, Sofia Bartlett, Héctor Alexander Velásquez García, Prince Adu, Amanda Yu, Maria Alvarez, Alnoor Ramji, Eric Yoshida, Mel Krajden, Naveed Janjua
Journal: Journal of Hepatology (2025)
SAT-419-YI A postbiotics and metabiotics reduces the hepatic steatosis indices and aminotransferase activity in MASLD patients: a randomized clinical trial (DELI_MASLD study)
Authors: Maryana Savytska, Yeva Ilkiv, Olena Baka, Elina Manzhalii, Tetyana Falalyeyeva, Viktoriia Yerokhovych, Liubov Sichel, Nazarii Kobyliak
Journal: Journal of Hepatology (2025)
SAT-353-YI Management of Wilson disease across europe: an international physician-oriented survey by the ERN-RARE liver group
Authors: Frederik Kirk, Karina Rewitz, Wiebke Papenthin, Zoe Mariño, Eduardo Couchonnal, Nicolas Lanthier, Marina Berenguer, Aurélia Poujois, Gerald Denk, Thomas Damgaard Sandahl
Journal: Journal of Hepatology (2025)
SAT-205 Dynopenia predicts mortality in patients with liver cirrhosis and hepatocellular carcinoma
Authors: Paolo Gallo, Valentina Flagiello, Antonio de Vincentis, Simone Di Cola, Francesca Terracciani, Andrea Falcomata’, Antonio Picardi, Umberto Vespasiani-Gentilucci
Journal: Journal of Hepatology (2025)
WED-430 Best buys to diagnose and treat metabolic dysfunction-associated steatohepatitis among people living with diabetes type 2: a multicountry generalized cost-effectiveness analysis
Authors: Jeffrey Lazarus, Leire Agirre-Garrido, Luis Antonio Diaz, Pojsakorn Danpanichkul, Sokoine Kivuyo, Loreta Kondili, Hannes Hagström, Hirokazu Takahashi, Juan Manuel Pericàs, C Wendy Spearman, Claudia P. Oliveira, Cristiane Villela-Nogueira, Jörn M. Schattenberg, Emilie Toresson Grip, Naim Alkhouri, Andrea Marcellusi, Henry E Mark, Alina M Allen, Nathalie Leite, Hussain Alomar, Saleh Alqahtani, Nicolai Brachowicz
Journal: Journal of Hepatology (2025)
FRI-180 Establishment of a sarcopenia decline curve for patients with liver cirrhosis to develop hepatic rehabilitation medicine
Authors: Hiroteru Kamimura, Shuji Terai, Miida Suguru, Hiroki Maruyama, Hiroyuki Abe, Saori Endo, Hitoshi Yoshiji, Masahito Shimizu, Takumi Kawaguchi, Tetsuya Tsuji
Journal: Journal of Hepatology (2025)
WED-211 Non-invasive evaluation of portal hypertension in patients with advanced chronic liver disease undergoing major abdominal surgery
Authors: Lidia Canillas, Amalia Pelegrina, Fawaz León, Aina Salis, Elena Colominas-González, Antonia Caro, Juan Sánchez-Parrilla, Juan Álvarez, Fernando Burdio, Jose A. Carrión
Journal: Journal of Hepatology (2025)
TOP-250 Polyreactive immunoglobulin G is elevated in autoimmune hepatitis and acute liver failure
Authors: Theresa Kirchner, Klaus Stahl, Benjamin Seeliger, Alejandro Campos-Murguia, George Dalekos, Kalliopi Zachou, Marcial Sebode, Ansgar W. Lohse, Maciej Janik, Piotr Milkiewicz, Mercedes Robles-Díaz, Raul J. Andrade, William Bernal, Mark J.W. McPhail, Francesca Trovato, Heiner Wedemeyer, Bastian Engel, Richard Taubert
Journal: Journal of Hepatology (2025)
SAT-176-YI Minimal serum creatinine fluctuations impact on prognosis in acutely decompensated cirrhosis
Authors: Marco Tizzani, Chiara Lisi, Matteo Botta, Alberto Calleri, Maria Laura Robone, Mimma Bonomo, Giulia Pecorella, Elisa Bertoldi, Francesco Frigo, Daniela Campion, Antonio Ottobrelli, Alfredo Marzano, Elisabetta Bugianesi, Giorgio Maria Saracco, Carlo Alessandria
Journal: Journal of Hepatology (2025)
SAT-496 Steatosis independent of fibrosis predict hepatic decompensation and mortality in patients with MetALD and ALD
Authors: Mette Lehmann Andersen, Nikolaj Torp, Stine Johansen, Camilla Dalby Hansen, Ellen Lyngbeck Jensen, Johanne Kragh Hansen, Katrine Bech, Helle Schnefeld, Georg Semmler, Peter Andersen, Ida Falk Villesen, Katrine Thorhauge, Katrine Lindvig, Maja Thiele, Aleksander Krag, Mads Israelsen
Journal: Journal of Hepatology (2025)
FRI-492 Torque Teno virus as a biomarker of immune status and attenuated immune response to vaccination in liver transplant recipients
Authors: Nicolas Ducasa, Paula Benencio, Maria Margarita Anders, Bianca Mazzitelli, Lucía Bleichmar, Manuel Barbero, Fernando Cairo, Natalia Sobenko, Patricia Etcheves, Giampaolo Scarton, Chiara Zecchin, Manuel Mendizabal, Florencia Quiroga, Mirna Biglione, Ezequiel Mauro
Journal: Journal of Hepatology (2025)
FRI-075-YI Differential granzyme-mediated immune responses in CXCR6 +PD-1+ CD8 T cells in acute versus chronic ALT flares
Authors: Roni Souleiman, Erich Freyer, Suparna Dey, Christine Falk, Benjamin Maasoumy, Heiner Wedemeyer, Anke R.M. Kraft, Bernd Heinrich, Markus Cornberg
Journal: Journal of Hepatology (2025)
FRI-211 Vasopressin is safe and effective as a second vasopressor in patients with cirrhosis and septic shock: results of the VITEL-C trial. NCT05315557
Authors: Rakhi Maiwall, Vishnu Girish, Harshvardhan Tevethia, Mohit Prajapati, Fagun Sharma, Dr. Prashant Mohan Agarwal, Satender Pal Singh, Vijayraghavan Rajan, Sumegh Talwalkar, Ayush Jain, Bindiya Arora, Priyanka Sharma, Charvi Nayyar, Sherin Thomas, Shiv Kumar Sarin
Journal: Journal of Hepatology (2025)
SAT-349 Liver disease in adults with fontan circulation: a cross-sectional study from a tertiary center in western Sweden
Authors: Elin Hultgren, Amanda Kullander, Zacharias Mandalenakis, Mikael Dellborg, Wai Giang Kok, Peter Eriksson, Frida Dangardt, Charlotte de Lange, Nikolaos Papachrysos
Journal: Journal of Hepatology (2025)
SAT-040 Identifying people who are HBV positive but undiagnosed: a model-based approach informed by health administrative data
Authors: Julien Smith-Roberge, Samantha Drover, Stanley Wong, Andrew Mendlowitz, Jordan J. Feld, Christina Greenaway, Naveed Janjua, Beate Sander, William W.L. Wong
Journal: Journal of Hepatology (2025)
SAT-172-YI Branched-chain amino acids in liver cirrhosis and hepatic encephalopathy: a meta-analysis of clinical evidence
Authors: Luise Aamann, Neha Deshpande, Gitte Dam, Mette Borre, Giulio Marchesini Reggiani, Inigo Les, Niels Kristian Aagaard, Hendrik Vilstrup, Lise Lotte Gluud
Journal: Journal of Hepatology (2025)
WED-170 Descriptive study of the impact of using non-cardioselective beta- blockers in cirrhotic patients after a first episode of ascites
Authors: Alejandro Fernandez Soro, Victoria Lobo Antuña, Inmaculada Castello, Mercedes De La Torre Sanchez, Moises Diago, Carlos Alventosa-Mateu
Journal: Journal of Hepatology (2025)
THU-209 Impact of hepatitis C eradication with direct-acting antivirals on metabolic and liver-related outcomes in diabetic patients
Authors: Clelia Asero, Claudia Grisanti, Giuseppina Russo, Annalisa Giandalia, Maria Stella Franzè, Concetta Pitrone, Roberto Filomia, Gaia Caccamo, Carlo Saitta, Angela Alibrandi, Irene Cacciola
Journal: Journal of Hepatology (2025)
SAT-275-YI Likelihood level of a functional HBV-specific CD8 cell response upon discontinuation of eAg(-) chronic hepatitis B treatment correlates with long-term clinical outcome
Authors: Henar Calvo Sánchez, Raquel Encijo, Julia Peña Asensio, Rocío López, Alberto Delgado, Joaquín Míquel, Alejandro González Praetorius, Miguel Torralba, Juan Ramón Larrubia
Journal: Journal of Hepatology (2025)
WED-315 Atherosclerotic cardiovascular risk in patients with chronic hepatitis B: Tenofovir Disoproxil fumarate vs Tenofovir Alafenamide from a korean nationwide study
Authors: Ji won Yang, Jihye Lim, Jina Park, Ye-Jee Kim, Hwa Jung Kim, Jonggi Choi
Journal: Journal of Hepatology (2025)
SAT-469 Maintaining a low to moderate alcohol consumption over time in MASLD patients increases the risk of fibrosis progression over moderate drinkers and MetALD patients
Authors: Ares Villagrasa, Anna Aguilar, Clara Sabiote, Alba Jiménez-Massip, Juan Manuel Pericàs, Meritxell Ventura Cots
Journal: Journal of Hepatology (2025)
TOP-218 Yaq-001 positively impacts gut microbiome composition, virulence, antimicrobial resistance gene profile resulting in significant effects on ammonia, endotoxemia and inflammation in cirrhosis patients
Authors: Jinxia Liu, Jose G. Guevara, Jane Macnaughtan, Yi Jin, Frederick Clasen, Annarein Kerbert, Theo Portlock, Javier Martínez González, Abeba Habtesion, Alexandra Phillips, Francesco de Chiara, Ganesh Ingavle, Cesar Jimenez, Giacomo Zaccherini, Kathrin Husi, Miguel Ángel Rodríguez-Gandía, Paul Cordero, Junpei Soeda, Jude Oben, Karen Church, Jia V. Li, Aarti Jalan, Pere Gineès, Elsa Sola, Simon Eaton, Caroline Morgan, Thomas Avery, Michal Kowalski, Daniel Green, Amir Gander, Lindsey Edwards, I. Jane Cox, Helena Cortez-Pinto, Reiner Wiest, Francois Durand, Paolo Caraceni, Roberto Elosua, Joan Vila, Marco Pavesi, Vicente Arroyo, Nathan Davies, Rajeshwar Prosad Mookerjee, Víctor Manuel Vargas Blasco, Susan Sandeman, Gautam Mehta, Julian R. Marchesi, Agustín Albillos, Fausto Andreola, Saeed Shoaie, Rajiv Jalan
Journal: Journal of Hepatology (2025)
SAT-080-YI The NLRP3 inflammasome and its downstream target Il1R, but not IL18R drive hepatocarcinogenesis
Authors: Mona Peltzer, Antje Mohs, Lena Susanna Candels, Ines Volkert, Jan G. Hengstler, Carolin V. Schneider, Serena Pelusi, Luca Valenti, Eicke Latz, Christian Trautwein, Kai Markus Schneider
Journal: Journal of Hepatology (2025)
WED-121 Comparison of clinical characteristics, risk factors and prognosis of HCC patients with lean and non-lean MASLD undergoing surgical resection
Authors: Chun-Ting Ho, Hao-Jan Lei, Gar-Yang Chau, Chia Jung Ho, Yi-Chen Lin, Yi-Hsiang Huang, Ming-Chih Hou, Jaw-Ching Wu, Chien-Wei Su
Journal: Journal of Hepatology (2025)
LBP-036-YI Suboptimal performances of Baveno VII and AASLD 2024 criteria for detecting clinically significant portal hypertension with varices in untreated patients with HDV cirrhosis
Authors: Maria Paola Anolli, Elisabetta Degasperi, Giulia Tosetti, Martina Lucà, Liana Gheorghe, Alessandro Loglio, Alessia Ciancio, Giampiero D’Offizi, Thomas Reiberger, Christoph Schramm, Maurizia Brunetto, Florian van Bömmel, Serena Zaltron, Laura Turco, Caroline Zöllner, Teresa Santantonio, Ivana Carey, Alessandro Federico, Loredana Sarmati, Maria Buti, Mariana Cardoso, Filomena Morisco, Margarita Papatheodoridi, Francesco Paolo Russo, Alessandra Mangia, Pierluigi Toniutto, Nicola Coppola, Christopher Dietz-Fricke, Jérôme Dumortier, Edoardo Giovanni Giannini, Elena Rosselli Del Turco, Soo Aleman, Stella de Nicola, Monia Maracci, Letizia Marinaro, Michele Milella, Adriano Pellicelli, Biagio Pinchera, Massimo Puoti, Dominique Roulot, Saveria Lory Croce’, Ivana Rita Maida, Uta Merle, Angelo Pan, Marcello Persico, Francesca Pileri, Antonietta Romano, Matteo Tonnini, Paola Vitiello, Rosa Zampino, Pietro Lampertico
Journal: Journal of Hepatology (2025)
THU-166 NTZ alleviates stress-induced hepatocyte cell death through modulation of oxidative stress and DNA damage signaling pathways in ACLF models
Authors: Marie Bobowski-Gerard, Nicolas Stankovic Valentin, Sylvie Deledicque, Simon Debaecker, Nina Tserstevens, Philippe Delataille, Sakina Sayah Jeanne, Dean Hum, Vanessa Legry, Jerôme Eeckhoute, Joan Clària, Bart Staels
Journal: Journal of Hepatology (2025)
SAT-514 High-risk PNPLA3 rs738409 genotype is associated with higher CCL2 concentrations in liver transplant candidates with alcohol - related liver disease
Authors: Tomislav Kelava, Ivan Budimir Bekan, Dino Šisl, Alan Šucur, Ana Bainrauch, Valerija Bralic-Lang, Pavao Planinić, Nataša Kovacèic, Danka Grcèevic, Vibor Šeša, Anna Mrzljak
Journal: Journal of Hepatology (2025)
TOP-380-YI Baseline liver elastography and its longitudinal changes predict liver-related outcomes in patients with metabolic dysfunction associated steatotic liver disease (MASLD)
Authors: Antonio Liguori, Lucrezia Petrucci, Francesco Pantaleo, Fadi Youssef, Giuseppe Marrone, Marco Biolato, Maurizio Pompili, Antonio Grieco, Antonio Gasbarrini, Luca Miele
Journal: Journal of Hepatology (2025)