tbuckley/cabot-search huggingface dataset:
Cancer Chemotherapy II. The Twenty-Second Hahnemann Symposium.
Authors: Isadore Brodsky, S. Benham Kahn, John Henry Moyer
Journal: Annals of Internal Medicine (1972)

Cancer chemotherapy II : the twenty-second Hahneman Sympsoium , Cancer chemotherapy II : the twenty-second Hahneman Sympsoium , کتابخانه مرکزی دانشگاه علوم پزشکی ایران
The Sanitary Institutions of the Imperial Government of Japan.
Authors: 内務省衛生局
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
WATS Telephone Therapy: New Follow-Up Technique for Alcoholics
Authors: RONALD J. CATANZARO, WILLIE GRAY GREEN
Journal: American Journal of Psychiatry (1970)

The authors present the rationale and description of a promising development in psychotherapy—WATS telephone therapy. In certain selected cases the formal regular use of the telephone to conduct routine psychotherapy has many advantages over traditional therapy. They describe the use of this method in following up alcoholics and express the belief that a similar plan might be helpful with other diagnostic groups such as opiate addicts, depressives, and schizophrenics.
Persistent perfectionism, symmetry, and exactness after long-term recovery from anorexia nervosa
Authors: N M Srinivasagam, W H Kaye, K H Plotnicov, C Greeno, T E Weltzin, R Rao
Journal: American Journal of Psychiatry (1995)

It is well recognized that patients with anorexia nervosa have perfectionistic and obsessive behaviors. This study investigated whether such behaviors persist after recovery.Twenty subjects who had recovered from anorexia nervosa were recruited for the study. They had been at normal weight and their menses had been regular for more than a year. These subjects were compared with 16 healthy women with the use of the Eating Disorder Inventory, the Frost Multidimensional Perfectionism Scale, and the Yale-Brown Obsessive Compulsive Scale.The recovered anorexic patients had significantly higher scores than the comparison women on the measures of perfectionism on the Eating Disorder Inventory and on overall perfectionism on the Frost scale. Moreover, the recovered patients had higher scores on the Yale-Brown scale, with target symptoms suggesting that many had specific concerns with symmetry and exactness.Certain characteristics of anorexia nervosa, such as a need for order and precision, persist after good outcome and recovery, raising the question of whether these behaviors are traits that contribute to the pathogenesis of this illness.
Clinicopathological Characteristics and A20 (TNFAIP3) Mutation In Primary Thyroid Lymphoma
Authors: Yasuko Hamada, Mariko Ishibashi, Toshio Asayama, Namiko Okuyama, Asaka Kondo, Keiichi Moriya, Hideya Hyodo, Takehito Igarashi, Hiroyuki Onose, Norio Yokose, Sakae Tanosaki, Kazuo Shimizu, Hideto Tamura, Koiti Inokuchi
Journal: Blood (2013)
Correlation of sorafenib plasma concentrations and clinical toxicity: A prospective population pharmacodynamic and pharmacokinetic study
Authors: B. Billemont, M. Hornecker, S. Ropert, B. Blanchet, J. Jais, P. Blanchard, J. Meric, J. Alexandre, M. Tod, F. Goldwasser
Journal: Journal of Clinical Oncology (2009)

e14585 Background: Sorafenib is an angiogenesis inhibitor recently approved for the treatment of metastatic renal cell carcinoma and hepatocarcinoma. This oral multi-targeted kinase inhibitor blocks the VEGF, PDGF receptors, BRAF and c-kit. In clinical trials, severe toxicities included rash, hand-foot syndrome and diarrhea. We investigated the relationship between severe toxicity and sorafenib plasmatic exposure. Patients and methods: From February 2008 to December 2008, 32 patients (pts) were treated with sorafenib (800 mg given daily). Clinical and blood exams were performed at baseline and every 2 weeks. Toxicity events were graded according to National Cancer Institute Common Toxicity Criteria 3.0. The sorafenib area under the plasma concentration-time curve over 12 hours (AUC0–12) was determined every 2 weeks by gradient elution liquid chromatography, data analysis with one-compartment disposition and a population approach using NONMEM software. Grade 3 toxicity free survival was estimated by Kaplan-Meier method. Results: Pts (23 males), ECOG 0–1 (27 pts), median age 62.8 years (range 37–78), with metastatic hepato-carcinoma (11), melanoma (6), thyroid cancer (8), renal cell carcinoma (7), received a median treatment duration of 94 days (range : 7–330). 20 pts experienced grade 3 toxicities with 33 events: hand-foot hyperkeratosis (14), diarrhea (5), cutanous rash (4), asthenia (2), anorexia (2), dyspnea (1), scrotal toxicity (1), post surgical complication (1), hypertension (1), increase creatinine level (1), digestive hemorrhage (1). The median AUC0–12 was 62.4 mg/L.h, ranging from 28.7 to 202.2 mg/L.h. Amongst pts experiencing grade 3 toxicity, two groups of 16 pts were defined with the median AUC0- 12 as cut off: low exposure (Lw) and high exposure (Hi). Six Lw pts experienced grade 3 toxicity versus 14 Hi pts (exact Fisher Test p=0.009). The probability of free grade 3 toxicity survival was higher for Lw (Logrank test p=0.004). Conclusions: These results show that grade 3 toxicity occurrence may be related to high plasma sorafenib exposure. This supports the need for therapeutic drug monitoring to prevent toxicity grade 3 occurrence and therefore optimize the clinical management of patients under sorafenib. No significant financial relationships to disclose.
A Short History of Psychiatric Achievement with a Forecast for the Future
Authors: Nolan D. C. Lewis
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Novel Th17-Prone CD146+CCR5+ T-Cell Population As an Early Marker of Intestinal Graft-Versus-Host Disease
Authors: Wei Li, Liangyi Liu, Aurelie Gomez, Qing Zhang, Jilu Zhang, Abdulraouf Ramadan, Christen L Mumaw, Joel K. Greenson, Suntrea Hammer, Jingmei Lin, Thomas M. Braun, Di Jiang, Elizabeth Virts, Stephanie L Kelich, Hong Wei Chu, Samir Hanash, Helmut Hanenberg, Sophie Paczesny
Journal: Blood (2014)
Traité d'hématologie clinique.
Authors: Jean Baptiste Eugène Rieux
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Clinical and pharmacokinetic phase I dose-finding study of kahalalide F (KF) administered as a prolonged infusion in patients with solid tumors
Authors: R. Salazar, E. Casado, A. Lopez Martin, B. Pardo, J. M. Roca, R. Rodriguez, M. Garcia, J. Tabernero, B. de las Heras, L. Paz-Ares
Journal: Journal of Clinical Oncology (2005)

2059 Background: KF is a cytotoxic cyclic peptide derived from the mollusc Elysia rufescens. Two prior phase 1 studies assessed 1 hour (h) infusions in 5-day 3-weekly and 1-day weekly schedules. The recommended doses (RD) were 560 and 650 μg/m2, respectively. The dose limiting toxicity (DLT) was reversible transaminase elevation (RTE) which was acute, asymptomatic and believed to be related to Cmax. A prolonged infusion may attenuate this effect and allow a higher non toxic systemic exposure. Therefore the current trial evaluates the safety and pharmacokinetics (PK) of prolonged (3h) weekly infusions to define its RD. Methods: The starting dose was 530 μg/m2. Cohorts of 3–6 patients were treated at increasing doses (530, 650, 800, 1000, 1200 and 1400 μg/m2), PK sampling being performed after the first and second infusion. Results: Thirty-six pts have been registered. Median age is 57 years (range 30–80) and median performance status is 0 (range 0–1). DLT was observed at the two higher dose levels (2/4 and 2/6 pts at 1400 and 1200 μ g/m2 respectively). DLT was grade 4 RTE. No other relevant toxicity has been observed, except paresthesias and pruritus on hands during and early post- infusion. The putative RD of 1000 μ g/m2 is being expanded to 13 pts. One complete response (CR) in non measurable lesions after 26 infusions was obtained in a locally advanced melanoma at 530 μg/m2. KF shows a rapid elimination half life (median 40 minutes) with restricted volume of distribution (median 8.3 L/m2). KF PK appears dose linear on graphical analysis in this schedule. Comparison of PK results at toxic levels in this study with those of prior studies shows that AUC values are similar, whereas Cmax values are lower, suggesting that DLTs are AUC rather than Cmax related. Conclusions: Weekly 3h infusions of KF are feasible and well tolerated. DLT was grade 4 acute, asymptomatic RTE. The RD of 1000 μg/m2 is being expanded to further characterize its toxicity and PK profile. No significant financial relationships to disclose.
Effect of Left Ventricular Diastolic Dysfunction on Incident Heart Failure and Mortality is Independent of Left Ventricular Geometry, Mass and Systolic Function
Authors: Ravi Desai Md, Mustafa I Ahmed Md, Mujib Mbbs, Mph, Marjan, Larry E Jacobs Md, Gregg C Fonarow Md, Gilbert J Perry Md, Wilbert S Aronow Md, Michael Zile Md, Ahmed Md, Mph, Ali
Journal: Circulation (2010)
Abstract 16846: Tricuspid Insufficiency After Laser Lead Extraction
Authors: Julian Mesa, Eric Arguelles, Roger C Carrillo
Journal: Circulation (2011)

Background The use of laser lead extraction (LLE) to remove pacemaker (PCM) and implantable cardiac defibrillator (ICD) leads has become more prevalent in the past decade. Though the procedure is associated with a low level of complications, LLE still poses some risks to patients. Some reports have suggested an increase in Tricuspid Insufficiency (TI) associated with LLE. We present a series of patients who underwent both LLE and complete evaluation for TI with echocardiographic techniques. Methods From August 2008 through January 2010, 173 prospective, consecutive patients underwent LLE in a single center. All patients had transesophageal echocardiograms (TEE) during the extraction. 53 patients had tricuspid valve function evaluated a day prior to the procedure with a transthoracic echocardiogram (TTE), during the procedure with a TEE and 2 days postoperatively with a TTE. Descriptive analysis of the data was performed. All echocardiography data was analyzed by a cardiologist specialized in cardiac echocardiograms. Results All 173 patients experienced no change in tricuspid valve function during the procedure with TEE. 53 patients had complete TI evaluation, 38 males (72%), 15 females (38%), and a mean age of 69.45±14.08. Mean ejection fraction was 35.82±14.72. 3 (6%) patients experienced tricuspid insufficiency after the procedure (2 mild and 1 severe, all with device endocarditis); 16 (30%) patients were found to have TI before LLE that returned to normal valve function during or after the procedure. 34 (64%) patients did not experience any significant change of the tricuspid valve performance after LLE. Conclusions Laser lead extraction was not associated with increased TI.
Biopsy Pathology of the Pulmonary Vasculature
Journal: Thorax (1990)

The open lung biopsy processing of biopsy specimens the normal lung vessels physiology and pathophysiology of the pulmonary circulation plexogenic arteriopathy evaluation of corrective operability of congenital heart disease thrombotic arteriopathy hypoxic arteriopathy congestive vasculopathy pulmonary venoocclusive disease vasculopathies in lung diseases pulmonary vasculitis vasculopathy in diminished flow and pulse pressure developmental disorders of lung vessels lung vessels and neoplastic disorders unexplained pulmonary hypertension - primary pulmonary hypertension sources of error.
Books for Tired Eyes: A List of Books in Large Print
Authors: Charlotte Matson, Lola Larson
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Meta-analysis of antidepressant prescribing
Authors: N. Freemantle, J. Mason
Journal: BMJ (1995)

patients with cancers before the skin cancer were retained in the analysis or not (Frisch et al, unpublished data).This argues against Sasieni and Bataille's proposal.By no means do we consider our observations to be evidence of a causal role for ultraviolet light in the pathogenesis of non-Hodgkin's lymphoma.Sasieni and Bataille and Robert Newton suggest that immunosuppression rather, than ultraviolet light explains our findings.We do not disagree with this.As we suggested in our paper, one of the possible mechanisms that link skin cancers and non-Hodgkin's lymphoma is the local and systemic immunological dysregulation caused by ultraviolet light.34The considerable indirect support for such an association5 needs further consideration.
Facing the Future's Risks: Studies toward Predicting the Unforeseen.
Authors: Lyman Bryson, Ralph H. Blanchard, Lawrence A. Fitzgerald
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Histopathology of Irradiation from External and Internal Sources
Authors: William Bloom
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
708 OVERLAPPING STRUCTURE OF HBV GENOME AND IMMUNE SELECTING PRESSURE ARE THE MAIN DRIVING FORCES FOR HBV EVOLUTION
Authors: V. Cento, C. Mirabelli, R. Salpini, Y. Han, F. Mercurio, S. Dimonte, B. Beggel, L. Wittkop, M. Fraune, C. Gori, A. Bertoli, V. Micheli, G. Gubertini, R. Longo, S. Romano, M. Visca, V. Gallinaro, N. Marino, F. Mazzotta, G.M. De Sanctis, P. Tremulet, M. Angelico, X.X. Zhang, J. Verheyen, F. Ceccherini Silberstein, C.F. Perno, V. Svicher
Journal: Journal of Hepatology (2011)
The Pre-School Child and His Posture: A Program of Corrective Exercises Through Games.
Authors: Frank Howard Richardson, Winifred Johnson Hearn
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Metabolism of Chicken Tumors&lt;xref ref-type="fn" rid="fn1"&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/xref&gt;
Authors: Dean Burk, Herbert Sprince, Juliet M. Spangler, Elvin A. Kabat, Jacob Furth, Albert Claude
Journal: JNCI Journal of the National Cancer Institute (1941)

Journal Article The Metabolism of Chicken Tumors Get access Dean Burk, Dean Burk senior chemist National Cancer Institute, National Institute of Health, United States Public Health Service Search for other works by this author on: Oxford Academic PubMed Google Scholar Herbert Sprince, Herbert Sprince Parker research fellow Search for other works by this author on: Oxford Academic PubMed Google Scholar Juliet M. Spangler, Juliet M. Spangler research assistant Department of Biochemistry Search for other works by this author on: Oxford Academic PubMed Google Scholar Elvin A. Kabat, Elvin A. Kabat instructor in pathology Search for other works by this author on: Oxford Academic PubMed Google Scholar Jacob Furth, Jacob Furth associate professor of pathology Department of Pathology Cornell University Medical College Search for other works by this author on: Oxford Academic PubMed Google Scholar Albert Claude Albert Claude associate Rockefeller Institute for Medical Research Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 2, Issue 3, December 1941, Pages 201–240, https://doi.org/10.1093/jnci/2.3.201 Published: 01 December 1941
Guardians to protect patient data
Authors: John Warden
Journal: BMJ (1999)

New watchdog figures, to be called Caldicott Guardians, will make their appearance throughout the NHS from April. Their duty will be to safeguard and protect the handling of confidential patient information as it passes between computers.

The name derives from the Caldicott review which reported just over a year ago ( BMJ 1997;315:1562) in response to a threatened BMA boycott of the NHS “net” because of the vulnerability of patient data flowing from clinical to administrative settings. The review was led by …