tbuckley/cabot-search huggingface dataset:
Beyond the Gut: The intratumoral microbiome's influence on tumorigenesis and treatment response
Authors: Hao Zhang, Li Fu, Xinwen Leiliang, Chunrun Qu, Wantao Wu, Rong Wen, Ning Huang, Qiuguang He, Quan Cheng, Guodong Liu, Yuan Cheng
Journal: Cancer Communications (2024)

The intratumoral microbiome (TM) refers to the microorganisms in the tumor tissues, including bacteria, fungi, viruses, and so on, and is distinct from the gut microbiome and circulating microbiota. TM is strongly associated with tumorigenesis, progression, metastasis, and response to therapy. This paper highlights the current status of TM. Tract sources, adjacent normal tissue, circulatory system, and concomitant tumor co-metastasis are the main origin of TM. The advanced techniques in TM analysis are comprehensively summarized. Besides, TM is involved in tumor progression through several mechanisms, including DNA damage, activation of oncogenic signaling pathways (phosphoinositide 3-kinase [PI3K], signal transducer and activator of transcription [STAT], WNT/β-catenin, and extracellular regulated protein kinases [ERK]), influence of cytokines and induce inflammatory responses, and interaction with the tumor microenvironment (anti-tumor immunity, pro-tumor immunity, and microbial-derived metabolites). Moreover, promising directions of TM in tumor therapy include immunotherapy, chemotherapy, radiotherapy, the application of probiotics/prebiotics/synbiotics, fecal microbiome transplantation, engineered microbiota, phage therapy, and oncolytic virus therapy. The inherent challenges of clinical application are also summarized. This review provides a comprehensive landscape for analyzing TM, especially the TM-related mechanisms and TM-based treatment in cancer.
Association of Urinary Metals With Cardiovascular Disease Incidence and All-Cause Mortality in the Multi-Ethnic Study of Atherosclerosis (MESA)
Authors: Irene Martinez-Morata, Kathrin Schilling, Ronald A. Glabonjat, Arce Domingo-Relloso, Melanie Mayer, Katlyn E. McGraw, Marta Galvez Fernandez, Tiffany R. Sanchez, Anne E. Nigra, Joel D. Kaufman, Dhananjay Vaidya, Miranda R. Jones, Michael P. Bancks, R. Graham Barr, Daichi Shimbo, Wendy S. Post, Linda Valeri, Steven Shea, Ana Navas-Acien
Journal: Circulation (2024)

BACKGROUND: Exposure to metals has been associated with cardiovascular disease (CVD) end points and mortality, yet prospective evidence is limited beyond arsenic, cadmium, and lead. In this study, we assessed the prospective association of urinary metals with incident CVD and all-cause mortality in a racially diverse population of US adults from MESA (the Multi-Ethnic Study of Atherosclerosis). METHODS: We included 6599 participants (mean [SD] age, 62.1 [10.2] years; 53% female) with urinary metals available at baseline (2000 to 2001) and followed through December 2019. We used Cox proportional hazards models to estimate the adjusted hazard ratio and 95% CI of CVD and all-cause mortality by baseline urinary levels of cadmium, tungsten, and uranium (nonessential metals), and cobalt, copper, and zinc (essential metals). The joint association of the 6 metals as a mixture and the corresponding 10-year survival probability was calculated using Cox Elastic-Net. RESULTS: During follow-up, 1162 participants developed CVD, and 1844 participants died. In models adjusted by behavioral and clinical indicators, the hazard ratios (95% CI) for incident CVD and all-cause mortality comparing the highest with the lowest quartile were, respectively: 1.25 (1.03, 1.53) and 1.68 (1.43, 1.96) for cadmium; 1.20 (1.01, 1.42) and 1.16 (1.01, 1.33) for tungsten; 1.32 (1.08, 1.62) and 1.32 (1.12, 1.56) for uranium; 1.24 (1.03, 1.48) and 1.37 (1.19, 1.58) for cobalt; 1.42 (1.18, 1.70) and 1.50 (1.29, 1.74) for copper; and 1.21 (1.01, 1.45) and 1.38 (1.20, 1.59) for zinc. A positive linear dose-response was identified for cadmium and copper with both end points. The adjusted hazard ratios (95% CI) for an interquartile range (IQR) increase in the mixture of these 6 urinary metals and the corresponding 10-year survival probability difference (95% CI) were 1.29 (1.11, 1.56) and –1.1% (–2.0, –0.05) for incident CVD and 1.66 (1.47, 1.91) and –2.0% (–2.6, –1.5) for all-cause mortality. CONCLUSIONS: This epidemiological study in US adults indicates that urinary metal levels are associated with increased CVD risk and mortality. These findings can inform the development of novel preventive strategies to improve cardiovascular health.
Features associated with different inflammatory phenotypes of calcium pyrophosphate deposition (<scp>CPPD</scp>) disease: study using data from the international <scp>ACR</scp>/<scp>EULAR CPPD</scp> classification criteria cohort
Authors: Tristan Pascart, Augustin Latourte, Sara K. Tedeschi, Nicola Dalbeth, Tuhina Neogi, Antonella Adinolfi, Uri Arad, Mariano Andres, Fabio Becce, Thomas Bardin, Edoardo Cipolletta, Hang‐Korng Ea, Georgios Filippou, Emilio Filippucci, John FitzGerald, Annamaria Iagnocco, Tim L. Jansen, Matthijs Janssen, Frédéric Lioté, Alexander So, Geraldine M. McCarthy, Roberta Ramonda, Pascal Richette, Ann Rosenthal, Carlo Scirè, Ettore Silvagni, Silvia Sirotti, Francisca Sivera, Lisa K. Stamp, William J. Taylor, Robert Terkeltaub, Hyon K. Choi, Abhishek Abhishek
Journal: Arthritis & Rheumatology (2024)

The study objective was to examine the disease, demographic, and imaging features associated with different inflammatory phenotypes of calcium pyrophosphate deposition (CPPD) disease, ie, recurrent acute calcium pyrophosphate (CPP) crystal arthritis, chronic CPP crystal inflammatory arthritis, and crowned dens syndrome (CDS).
Health at a crossroads: future of the European Union hangs in the balance
Authors: None The Lancet Regional Health – Europe
Journal: The Lancet Regional Health - Europe (2024)

In June, 185 million Europeans cast their votes to elect 720 Members of the European Parliament (MEPs), the world's only directly elected transnational assembly. Despite the significance of this election, the voter turnout was disappointing at 51%, ranging from less than 30% in Croatia and Lithuania to more than 80% in Belgium and Luxembourg. The centre-right European People's Party and the centre-left Socialists and Democrats remained the most voted, securing around 25% and 20% of seats, respectively.
aKNNO: single-cell and spatial transcriptomics clustering with an optimized adaptive k-nearest neighbor graph
Authors: Jia Li, Yu Shyr, Qi Liu
Journal: Genome biology (2024)

Abstract Typical clustering methods for single-cell and spatial transcriptomics struggle to identify rare cell types, while approaches tailored to detect rare cell types gain this ability at the cost of poorer performance for grouping abundant ones. Here, we develop aKNNO to simultaneously identify abundant and rare cell types based on an adaptive k -nearest neighbor graph with optimization. Benchmarking on 38 simulated and 20 single-cell and spatial transcriptomics datasets demonstrates that aKNNO identifies both abundant and rare cell types more accurately than general and specialized methods. Using only gene expression aKNNO maps abundant and rare cells more precisely compared to integrative approaches.
Current genomic deep learning models display decreased performance in cell type-specific accessible regions
Authors: Pooja Kathail, Richard W. Shuai, Ryan Chung, Chun Jimmie Ye, Gabriel B. Loeb, Nilah M. Ioannidis
Journal: Genome biology (2024)

Abstract Background A number of deep learning models have been developed to predict epigenetic features such as chromatin accessibility from DNA sequence. Model evaluations commonly report performance genome-wide; however, cis regulatory elements (CREs), which play critical roles in gene regulation, make up only a small fraction of the genome. Furthermore, cell type-specific CREs contain a large proportion of complex disease heritability. Results We evaluate genomic deep learning models in chromatin accessibility regions with varying degrees of cell type specificity. We assess two modeling directions in the field: general purpose models trained across thousands of outputs (cell types and epigenetic marks) and models tailored to specific tissues and tasks. We find that the accuracy of genomic deep learning models, including two state-of-the-art general purpose models―Enformer and Sei―varies across the genome and is reduced in cell type-specific accessible regions. Using accessibility models trained on cell types from specific tissues, we find that increasing model capacity to learn cell type-specific regulatory syntax―through single-task learning or high capacity multi-task models―can improve performance in cell type-specific accessible regions. We also observe that improving reference sequence predictions does not consistently improve variant effect predictions, indicating that novel strategies are needed to improve performance on variants. Conclusions Our results provide a new perspective on the performance of genomic deep learning models, showing that performance varies across the genome and is particularly reduced in cell type-specific accessible regions. We also identify strategies to maximize performance in cell type-specific accessible regions.
Annelid methylomes reveal ancestral developmental and aging-associated epigenetic erosion across Bilateria
Authors: Kero Guynes, Luke A. Sarre, Allan M. Carrillo-Baltodano, Billie E. Davies, Lan Xu, Yan Liang, Francisco M. Martín-Zamora, Paul J. Hurd, Alex de Mendoza, José M. Martín-Durán
Journal: Genome biology (2024)

Abstract Background DNA methylation in the form of 5-methylcytosine (5mC) is the most abundant base modification in animals. However, 5mC levels vary widely across taxa. While vertebrate genomes are hypermethylated, in most invertebrates, 5mC concentrates on constantly and highly transcribed genes (gene body methylation; GbM) and, in some species, on transposable elements (TEs), a pattern known as “mosaic”. Yet, the role and developmental dynamics of 5mC and how these explain interspecies differences in DNA methylation patterns remain poorly understood, especially in Spiralia, a large clade of invertebrates comprising nearly half of the animal phyla. Results Here, we generate base-resolution methylomes for three species with distinct genomic features and phylogenetic positions in Annelida, a major spiralian phylum. All possible 5mC patterns occur in annelids, from typical invertebrate intermediate levels in a mosaic distribution to hypermethylation and methylation loss. GbM is common to annelids with 5mC, and methylation differences across species are explained by taxon-specific transcriptional dynamics or the presence of intronic TEs. Notably, the link between GbM and transcription decays during development, alongside a gradual and global, age-dependent demethylation in adult stages. Additionally, reducing 5mC levels with cytidine analogs during early development impairs normal embryogenesis and reactivates TEs in the annelid Owenia fusiformis . Conclusions Our study indicates that global epigenetic erosion during development and aging is an ancestral feature of bilateral animals. However, the tight link between transcription and gene body methylation is likely more important in early embryonic stages, and 5mC-mediated TE silencing probably emerged convergently across animal lineages.
MAMS: matrix and analysis metadata standards to facilitate harmonization and reproducibility of single-cell data
Authors: Irzam Sarfraz, Yichen Wang, Amulya Shastry, Wei Kheng Teh, Artem Sokolov, Brian R. Herb, Heather H. Creasy, Isaac Virshup, Ruben Dries, Kylee Degatano, Anup Mahurkar, Daniel J. Schnell, Pedro Madrigal, Jason Hilton, Nils Gehlenborg, Timothy Tickle, Joshua D. Campbell
Journal: Genome biology (2024)

Many datasets are being produced by consortia that seek to characterize healthy and disease tissues at single-cell resolution. While biospecimen and experimental information is often captured, detailed metadata standards related to data matrices and analysis workflows are currently lacking. To address this, we develop the matrix and analysis metadata standards (MAMS) to serve as a resource for data centers, repositories, and tool developers. We define metadata fields for matrices and parameters commonly utilized in analytical workflows and developed the rmams package to extract MAMS from single-cell objects. Overall, MAMS promotes the harmonization, integration, and reproducibility of single-cell data across platforms.
Intracranial Atherosclerotic Disease and Incident Dementia: The ARIC Study (Atherosclerosis Risk in Communities)
Authors: Di Zhao, Eliseo Guallar, Ye Qiao, David S. Knopman, Maylin Palatino, Rebecca F. Gottesman, Thomas H. Mosley, Bruce A. Wasserman
Journal: Circulation (2024)

BACKGROUND: Studies of the neurovascular contribution to dementia have largely focused on cerebral small vessel disease (CSVD), but the role of intracranial atherosclerotic disease (ICAD) remains unknown in the general population. The objective of this study was to determine the risk of incident dementia from ICAD after adjusting for CSVD and cardiovascular risk factors in a US community-based cohort. METHODS: We acquired brain magnetic resonance imaging examinations from 2011 through 2013 in 1980 Black and White participants in the ARIC study (Atherosclerosis Risk in Communities), a prospective cohort conducted in 4 US communities. Magnetic resonance imaging examinations included high-resolution vessel wall magnetic resonance imaging and magnetic resonance angiography to identify ICAD. Of these participants, 1590 without dementia, without missing covariates, and with adequate magnetic resonance image quality were followed through 2019 for incident dementia. Associations between ICAD and incident dementia were assessed using Cox proportional hazard ratios adjusted for CSVD (characterized by white matter hyperintensities, lacunar infarctions, and microhemorrhages), APOE4 genotype (apolipoprotein E gene ε4), and cardiovascular risk factors. RESULTS: The mean age (SD) of study participants was 77.4 (5.2) years. ICAD was detected in 34.6% of participants. After a median follow-up of 5.6 years, 286 participants developed dementia. Compared with participants without ICAD, the fully adjusted hazard ratios (95% CIs) for incident dementia in participants with any ICAD, with ICAD only causing stenosis ≤50%, and with ICAD causing stenosis &gt;50% in ≥1 vessel were 1.57 (1.17–2.11), 1.41 (1.02–1.95), and 1.94 (1.32–2.84), respectively. ICAD was associated with dementia even among participants with low white matter hyperintensities burden, a marker of CSVD. CONCLUSIONS: ICAD was associated with an increased risk of incident dementia, independent of CSVD, APOE4 genotype, and cardiovascular risk factors. The increased risk of dementia was evident even among participants with low CSVD burden, a group less likely to be affected by vascular dementia, and in participants with ICAD causing only low-grade stenosis. Our results suggest that ICAD may partially mediate the effect that cardiovascular risk factors have on the brain leading to dementia. Both ICAD and CSVD must be considered to understand the vascular contributions to cognitive decline.
Prolonged vs shorter awake prone positioning for COVID-19 patients with acute respiratory failure: a multicenter, randomised controlled trial
Authors: Ling Liu, Qin Sun, Hongsheng Zhao, Weili Liu, Xuehua Pu, Jibin Han, Jiangquan Yu, Jun Jin, Yali Chao, Sicong Wang, Yu Liu, Bin Wu, Ying Zhu, Yang Li, Wei Chang, Tao Chen, Jianfeng Xie, Yi Yang, Haibo Qiu, Arthur Slutsky, Ling Liu, Haibo Qiu, Hongsheng Zhao, Shu Lu, Chenliang Sun, Weili Liu, Yali Chao, Ying Zhu, Ruiqiang Zheng, Jiangquan Yu, Jun Wang, Jun Jin, Xuehua Pu, Yu Liu, Qindong Shi, Hongliang Wang, Sicong Wang, Bin Wu, Huaguang Ye, Jibin Han, Tao Chen, Qin Sun, Wei Chang, Bingwei Chen, Tao Chen
Journal: Intensive Care Medicine (2024)

Awake prone positioning has been reported to reduce endotracheal intubation in patients with coronavirus disease 2019 (COVID-19)-related acute hypoxemic respiratory failure (AHRF). However, it is still unclear whether using the awake prone positioning for longer periods can further improve outcomes.
Modernizing the NCI60 Cell Line Screen for Phenotypic Drug Discovery in the 21st Century
Authors: Gianna M. Colombo, Steven M. Corsello
Journal: Cancer Research (2024)

Over the past three decades, high-throughput phenotypic cancer cell line screens have revealed unanticipated small-molecule activities and illuminated connections between tumor genotypes and anticancer efficacy. Founded in 1984, the National Cancer Institute's "NCI60" screen laid the conceptual groundwork for the contemporary landscape of phenotypic drug discovery. NCI60 first operated as a primary bioactivity screen, but molecular characterization of the NCI60 cell line panel and development of a small-molecule sensitivity pattern recognition algorithm (called "COMPARE") have enabled subsequent studies into drug mechanisms of action and biomarker identification. In this issue of Cancer Research, Kunkel and colleagues report an updated version of the NCI60 screen, dubbed "HTS384" NCI60, that better aligns with current cell proliferation assay standards and has higher throughput. Changes include the use of a 384-well plate format, automated laboratory equipment, 3 days of compound exposure, and a CellTiter-Glo luminescent endpoint. To confirm that data from the HTS384 and classic NCI60 screen are comparable, the authors tested a library of 1,003 anticancer agents using both protocols and applied COMPARE to analyze patterns of cell line sensitivities. More than three dozen groups of targeted therapies showed high comparability between screens. Modernization of NCI60, and closer integration with other large-scale pharmacogenomic screens and molecular feature sets, will help this public screening service remain pertinent for cancer drug discovery efforts for years to come. See related article by Kunkel et al., p. 2403.
POS0490 INEFFECTIVENESS OF CONTROLLING DISEASE ACTIVITY ALONE IN PREVENTING THE PROGRESSION OF RHEUMATIC FRAILTY IN RHEUMATOID ARTHRITIS PATIENTS
Authors: Y. Ohashi, N. Takahashi, M. Suzuki, Y. Sobue, K. Terabe, S. Asai, S. Imagama
Journal: Annals of the Rheumatic Diseases (2024)
Sexual Identity Continuity and Change in a U.S. National Probability Sample of Sexual Minority Adults: Associations With Mental Health and Problematic Substance Use
Authors: Evan A. Krueger, Meg D. Bishop, Allen B. Mallory, Ankur Srivastava, Stephen T. Russell
Journal: American Journal of Psychiatry (2024)

Sexual minority disparities in behavioral health (e.g., mental health and substance use) are well-established. However, sexual identity is dynamic, and changes are common across the life course (e.g., identifying with a monosexual [lesbian or gay] label and later with a plurisexual [queer, pansexual, etc.] label). This study assessed whether behavioral health risks coincide with sexual identity change among sexual minority people.
Psychiatric Diagnoses in Parents and Psychiatric, Behavioral, and Psychosocial Outcomes in Their Offspring: A Swedish Population-Based Register Study
Authors: Mengping Zhou, Christine Takami Lageborn, Arvid Sjölander, Henrik Larsson, Brian D’Onofrio, Mikael Landén, Paul Lichtenstein, Erik Pettersson
Journal: American Journal of Psychiatry (2024)

Associations were examined between six psychiatric diagnoses in parents and a broad range of psychiatric and nonpsychiatric outcomes in their offspring.
POS0634 PHARMACOKINETICS, USABILITY AND SAFETY OF TOCILIZUMAB BIOSIMILAR (CT-P47) ADMINISTERED SUBCUTANEOUSLY BY AUTO-INJECTOR OR PRE-FILLED SYRINGE
Authors: E. Keystone, G. R. Burmester, J. S. Smolen, K. S. Yu, H. Ryu, D. Shin, M. Park, J. Hwang, S. J. Moon, M. Kim, P. A. Klimiuk, J. Trefler, J. Jaworski, S. H. Kim, Y. Bae, D. Jeon, H. Lee, J. Jang, J. Bae, H. Lee
Journal: Annals of the Rheumatic Diseases (2024)
AB0404 REAL WORLD DATA ON THE EFFECTIVENESS OF SECUKINUMAB ON JOINTS, PAIN, AND DISEASE ACTIVITY IN PSORIATIC ARTHRITIS PATIENTS – RESULTS FROM THE GERMAN AQUILA STUDY
Authors: U. Kiltz, E. Riechers, K. Gente, S. Bär, M. Fliesser, D. Peterlik, J. Brandt-Juergens
Journal: Annals of the Rheumatic Diseases (2024)
POS0620 IMMUNOGENICITY OF THE RECOMBINANT ZOSTER VACCINE IN PEOPLE WITH RHEUMATOID ARTHRITIS USING ABATACEPT
Authors: K. L. Winthrop, J. A. Hawkins, A. Weinberg, S. A. R. Siegel, J. L. Baxter, K. Garth, J. E. Huffstutter, J. Loveless, D. Ridley, E. Moreta, I. Messaoudi, J. R. Curtis
Journal: Annals of the Rheumatic Diseases (2024)
POS0487 PROGNOSIS PREDICTION IN SHORT AFTER BIOLOGICAL OR TARGETED SYNTHETIC DISEASE-MODIFYING ANTI-RHEUMATIC DRUG ADMINISTRATION USING A PROGNOSTIC NUTRITIONAL INDEX FOR PATIENTS WITH RHEUMATOID ARTHRITIS
Authors: I. Yoshii, N. Sawada, T. Chijiwa
Journal: Annals of the Rheumatic Diseases (2024)
OP0290 CLINICAL UTILITY OF EXOME SEQUENCING IN ADULTS WITH AUTOINFLAMMATORY DISORDERS
Authors: A. Fayand, M. Delplanque, L. Savey, D. Boutboul, P. Legendre, V. Geromel, T. Benquey, L. Raymond, S. Georgin-Lavialle
Journal: Annals of the Rheumatic Diseases (2024)
OP0301 CLINICAL AND BIOLOGICAL CHARACTERISTICS OF VEXAS SYNDROME IN WOMEN: STUDY OF 9 FRENCH CASES COMPARED WITH 263 MEN
Authors: R. Bourguiba, V. Lacombe, V. Jachiet, T. Comont, J. Galland, M. Heiblig, A. Nguyen, A. Aouba, X. Boulu, A. Curie, P. Sujobert, P. Hirsch, K. Olivier, A. Mekinian, B. Terrier, S. Georgin-Lavialle
Journal: Annals of the Rheumatic Diseases (2024)
AB0342 BURDEN AND CURRENT NON-SURGICAL MANAGEMENT OF MODERATE-TO-SEVERE PAIN ASSOCIATED WITH KNEE OSTEOARTHRITIS: A LITERATURE REVIEW
Authors: F. Castro-Domínguez, C. Tibesku, T. Mcalindon, S. Ivanavicius, R. Freitas, P. Kandaswamy, A. Sears, A. Latourte
Journal: Annals of the Rheumatic Diseases (2024)
AB0452 THE EFFECTS OF WEIGHT LOSS TREATMENT ON BIOMARKERS AND BONE MINERAL DENSITY IN PATIENTS WITH PSORIATIC ARTHRITIS AND OBESITY AND MATCHED CONTROLS
Authors: L. Torres, H. Forsblad-D’elia, I. Larsson, B. Eliasson, E. Klingberg, C. Jonsson, A. Bilberg, A. Landgren, I. Gjertsson
Journal: Annals of the Rheumatic Diseases (2024)
POS0958 CLINICAL AND ULTRASOUND FINDINGS IN DIFFICULT-TO-TREAT PSA: RESULTS FROM THE LEEDS SPECIALIST SPONDYLOARTHRITIS SERVICE
Authors: S. Harrison, O. Hen, A. Di Matteo, K. Naraghi, J. Weddell, Z. Vowden, C. Vandevelde, J. Freeston, A. Barr, D. Mcgonagle, H. Marzo-Ortega
Journal: Annals of the Rheumatic Diseases (2024)
AB0285 IMPACT OF THORACIC VERTEBRAL FRACTURES ON THE PROGNOSIS OF PATIENTS WITH CHRONIC LUNG DISEASE: A RETROSPECTIVE STUDY
Authors: A. Mayo-Juanatey, L. Perea-Galera, J. Lacasa-Molina, A. Herrejón-Silvestre, À. Martínez-Ferrer, P. León-Torralba, P. Andújar-Brazal, C. Valera-Ribera, A. Taberner-Cortés, I. Vázquez-Gómez, E. Valls-Pascual, D. Ybáñez-García, J. J. Alegre-Sancho
Journal: Annals of the Rheumatic Diseases (2024)
AB0502 CELLULAR AND PROTEOMIC CHANGES FOLLOWING ADMINISTRATION OF PERESOLIMAB, IN A PHASE 2A TRIAL IN RHEUMATOID ARTHRITIS
Authors: R. Benschop, J. Tuttle, P. Emery, C. Preuss, M. Daniels, C. Y. Chang, P. Yachi, A. Nirula
Journal: Annals of the Rheumatic Diseases (2024)
OP0089 PHASE 2 SAFETY AND EFFICACY OF SUBCUTANEOUS (S.C.) DOSE IANALUMAB (VAY736; ANTI-BAFFR mAb) ADMINISTERED EVERY 4 WEEKS UP TO 48 WEEKS IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)
Authors: N. Agmon-Levin, S. Ignatenko, A. Gordienko, J. Cortés-Hernández, P. Narongroeknawin, K. Romanowska -Prochnicka, N. Shen, H. Ciferská, M. Kodera, J. C. C. Wei, P. Leszczynski, J. L. Lan, E. Mysler, R. Wojciechowski, T. Tarr, E. Vishneva, Y. H. Chen, Y. Kaneko, S. Finzel, A. Hoi, M. Okada, A. Koolvisoot, S. S. Lee, L. Dai, H. Kaneko, B. Rojkovich, L. Sun, E. Zotkin, J. F. Viallard, M. Katayama, B. P. Magallares, T. Sengupta, C. Sips, C. Lau, A. Avrameas, S. Oliver
Journal: Annals of the Rheumatic Diseases (2024)
POS0960 REGIONAL VARIABILITY IN PSORIATIC ARTHRITIS DISEASE CHARACTERISTICS, SOCIAL DETERMINANTS OF HEALTH AND HEALTH EQUITY: EXAMINING DISTRIBUTION OF PATIENT BURDEN AND PHYSICIAN CARE IN THE UNITED STATES
Authors: B. Banbury, C. Jenkins, S. Dowell, E. Holladay, C. Clinton, F. Xie, J. Zhang, G. Wright, J. R. Curtis, G. Kerr
Journal: Annals of the Rheumatic Diseases (2024)