An Experimental Basis for Intravenous Vaccine Therapy in Chronic Arthritis With a Summary of Results Obtained in Patients
Authors: B. J. Clawson, M. Wetherby
Journal: Annals of Internal Medicine (1932)

Article1 June 1932An Experimental Basis for Intravenous Vaccine Therapy in Chronic Arthritis With a Summary of Results Obtained in PatientsB. J. CLAWSON, M.D., M. WETHERBY, M.D.B. J. CLAWSON, M.D.Search for more papers by this author, M. WETHERBY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-5-12-1447 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe factors considered as a basis for intravenous streptococcic vaccination reported in this paper are (1) etiology and (2) a method of vaccination which will not produce hypersensitiveness (allergy) but will desensitize patients already hypersensitive and will produce a high degree of protective immunity.ETIOLOGYThe belief that most cases of chronic arthritis are infectious in origin is quite generally accepted. The exact infectious agent and the manner and the form in which the agent finds its way into the joints are not so generally agreed upon. Some people believe that there is a direct infection of the joint by...References1 MOONEDWARDS VCSH: Results of blood cultures in rheumatoid arthritis, Jr. Infect. Dis., 1917, xxi, 154. CrossrefGoogle Scholar2 RICHARDS JH: Bacteriologic studies in chronic arthritis and chorea, Jr. Bact., 1920, v, 511. CrossrefGoogle Scholar3 HADJOPOULOSBURBANK LGR: A preliminary study bearing on the causative factors of multiple infectious arthritis, Jr. Bone and Joint Surg., 1927, ix, 278. Google Scholar4 CECILNICHOLLSSTAINSBY RLEEWJ: The bacteriology of the blood and joints in chronic infectious arthritis, Arch. Int. Med., 1929, xliii, 571. CrossrefGoogle Scholar5 KLUGH GF: Streptococci from blood cultures in arthritis, So. Med. Jr., 1931, xxiv, 706. 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Author, Article, and Disclosure InformationAffiliations: Minneapolis, Minn.*Presented at the San Francisco meeting of the American College of Physicians, April 6, 1932.†From the Departments of Pathology and Medicine of the University of Minnesota. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAllergic relations of normal and abnormal floras of the intestine 1 June 1932Volume 5, Issue 12Page: 1447-1461KeywordsAllergy and immunologyArthritisEtiologyImmunityVaccines ePublished: 1 December 2008 Issue Published: 1 June 1932 PDF downloadLoading ...