tbuckley/cabot-search huggingface dataset:
Microbiological assessment of bile in patients undergoing Endoscopic Retrograde Cholangiography: the “MICROBILE” Registry
Authors: C. Binda, G. Gibiino, B. Perini, C. Coluccio, S. Fabbri, P. Giuffrida, A. Cucchetti, C. Alessandro, G. Lucchi, F. Cristini, L. Raumer, E. Savarino, M. Cricca, V. Sambri, C. Fabbri
Journal: Endoscopy (2024)

Aims Biliary tree has been considered sterile under normal conditions. However, recent evidence revealed rich microbial communities in the biliary tract of patients affected by pancreaticobiliary disorders. We performed a prospective observational study aimed to evaluate the prevalence and the resistance profile of biliary pathogens in patients with naïve papilla with several pancreatobiliary diseases.
Oncologic efficacy of ESD in Early Colorectal Adenocarcinoma
Authors: D. de Frutos, J. Santiago Garcia, F. Valentin Gomez, A. Martins Pinto da Costa, E. Santos Pérez, E. Blázquez, B. Molinero, A. Herreros De Tejada Echanojauregui
Journal: Endoscopy (2024)

Aims Endoscopic submucosal dissection (ESD) can be established as a first-line treatment for Early Colorectal Adenocarcinoma (ECRAC). However, the presence of histological high-risk factors (HHRF) can limit its curative efficacy and lead to perform complementary treatments.
Drain-assisted EUS-guided gastroenterostomy in the treatment of gastroparesis refractory to endoscopic pyloromyotomy by GPOEM: a novel promising therapeutic option
Authors: J. M. Gonzalez, M. Gasmi, V. Vitton, M. Barthet
Journal: Endoscopy (2024)

Aims Gastric peroral endoscopic myotomy (GPOEM)has become an important treatment for refractory gastroparesis, demonstrating efficacy of around 65-70% in the last 2 randomized studies. Nevertheless, 30% of patients are non-responders, with few alternatives for them. In parallel, endoscopic ultrasound guided gastroenterostomies (EUS-GEA) has been developed in recent years for malignant, and more recently benign, antropyloric obstructions, with excellent clinical results (>90%). We present the results of this technique in gastroparesis refractory to GPOEM.
Endoscopic subserosal dissection of a large gastric GIST with risk factors
Authors: J. C. Balboa, R. Muñoz-González, M. Rosinach, A. Ortega Sabater, J. Michelena, R. Temiño López-Jurado, A. Mata, R. Turro, J. Espinós, H. Uchima
Journal: Endoscopy (2024)

Abstract Text An 87-year-old patient with an intraluminal-predominant gastric GIST displaying risk factors on endoscopic ultrasound (growth from 19mm to 31mm in 2 years and a necrotic focus). Endoscopic dissection around the GIST was performed using Splash M Knife. Due to involvement of the muscularis propria, subserosal dissection was performed. Endoscopic suturing with Apollo Overstitch was carried out. Due to the large lesion size (5cm), sample fragmentation was necessary for oral extraction. Pathology report revealed a low-risk GIST (<5 mitoses/50 HPF, no necrotic foci).Endoscopic treatment of gastric GISTs>3cm could be considered as an alternative in individualized cases.
Endorectal endoscopic ultrasound for the locoregional staging of rectal mucosal lesions: retrospective multicenter analysis
Authors: A. Mauriello, F. Fimiano, M. Degan, A. Borsato, A. Caneglias, M. T. Staiano, E. Dall'Amico, N. Pagano, M. Sacco, C. De Angelis
Journal: Endoscopy (2024)

Aims Colorectal cancer (CRC) is a common and growing disease and an accurate preoperative staging is essential to choose the most appropriate treatment. There is still debate on the role of transrectal endoscopic ultrasound (TREUS) in locoregional staging. The aim of this study is to establish its role in selecting the most suitable treatment.
Gastrointestinal bleeding and aortic stenosis: Heyde&amp;apos;s syndrome
Authors: A. Kostandini, C. Todeschini, A. L. Iasci, I. Pierantonelli, P. Sassaroli, M. Calzolari, M. Mancinelli, A. Di Sario
Journal: Endoscopy (2024)

Abstract Text An 80-year-old man presented to the Emergency Department of our Hospital with rectal bleeding and anemia. The patient had a history of atrial fibrillation being treated with DOAC and severe aortic stenosis. The patient underwent upper and lower endoscopy and small-bowel capsule endoscopy; small angiodysplasias were found in the cecum and in the ileum with no active bleeding. We suspected Heyde's syndrome and referred the patient to the Cardiac Surgery Department; transcatheter aortic valve implantation was performed and the patient has experienced no further episodes of gastrointestinal bleeding or anemia. [1] [2] [3]
Diagnostic performance of the newly developed endoscopic ultrasound visualization technique for low velocity blood flow in pancreatic ductal adenocarcinoma
Authors: T. Hayakawa, M. Horibe, E. Iwasaki, H. Okada, Y. Nakajima, A. Kayashima, S. Kawsaki, Y. Masugi, M. Kitago, T. Kanai
Journal: Endoscopy (2024)

Aims Detective flow imaging using endoscopic ultrasound (DFI-EUS) is a novel imaging modality for low-velocity blood flow. The diagnostic criteria or performance in pancreatic ductal carcinoma (PDAC) have not been reported yet. This study aimed to identify the accuracy of DFI-EUS in diagnosing PDAC.
Vena cava tumor as a differential diagnosis of retroperitoneal lesion
Authors: B. Tormo Lanseros, B. Agudo, J. E. Ruiz Becerra, E. Santos Perez, G. M. Jimenez, J. L. Lucena De La Poza, M. González-Haba Ruiz
Journal: Endoscopy (2024)

Abstract Text 67-year-old women presenting low back pain. Abdominal CT is performed showing a 4 x 5 cm retroperitoneal lesion, located in the second to third duodenal portion, close to de inferior vena cava (IVC). Endoscopic ultrasonography (EUS) describes a hypoechoic and heterogeneous mass, with no clear origin. EUS fine-needle biopsy (FNB) is made using a 22 G needle (Sharckcore), and the result of the histology is compatible with a mesenchymal neoplasia with proliferation of spindle cells. En bloc resection is achieved by surgery, following reconstruction with a ringed PTFE graft. Final diagnosis is consistent with a well-differentiated leiomyosarcoma of the IVC. This is a rare neoplasia, most common in women between 40 and 60 years. The clinical and radiological appearance are unspecific. EUS-FNB is a good tool to achieve de diagnosis and the surgical intervention is the treatment of choice [1] [2].
Evaluation of the safety and utility of the Radiofrequency Vapor Ablation (RFVA) system for duodenal mucosal ablation in a porcine model: a novel therapeutic strategy for type 2 diabetes (T2D)
Authors: B. Norton, A. Papaefthymiou, K. Chang, S. Mcgill, T. Spangler, V. K. Sharma, R. Haidry
Journal: Endoscopy (2024)

Aims Duodenal mucosal ablation (DA) is a promising endoscopic treatment for metabolic disease including T2D. A multitude of technologies are in development; however, limitations exist around usability, ablation uniformity, and adverse events. Vapor ablation, using the FDA cleared Aqua Medical RFVA system, is an emerging therapy that could be used for DA. Proof-of-concept data in Barrett's esophagus has established its safety and technical feasibility [1]. We aimed to evaluate the safety and utility of RFVA in the duodenum in a porcine dosimetry pre-clinical study.
Gastroscopy yield in the young: Comprehensive assessment of endoscopic and histologic findings. A comparative study
Authors: F. Abu Baker, R. Natour, D. Nicola, A. Beshara, B. Ovadia, Y. Kopelman
Journal: Endoscopy (2024)

Aims The escalating utilization of gastroscopy in young individuals necessitates an in-depth examination of its diagnostic yield and outcomes in this population. This study aims to investigate and compare various aspects of gastroscopy between young and older adults, shedding light on age-related differences in indications, endoscopic findings, histologic outcomes, and clinically significant findings (CSFs).
Comparative efficacy of different bowel preparations for colonoscopy: a network meta-analysis
Authors: M. Maida, G. Marasco, L. Fuccio, A. Vitello, F. Mocciaro, M. Amata, A. Fabbri, R. Di Mitri, R. Vassallo, D. Ramai, A. Facciorusso
Journal: Endoscopy (2024)

Aims Colonoscopy quality strictly depends on adequate bowel cleansing, which may affect the diagnostic accuracy and detection of adenomas. Many products for bowel cleansing have been proposed to date, but their comparative efficacy is still unclear. This systematic review with network meta-analysis aims to compare the performance of different bowel preparations for colonoscopy.
The nurse role in the transplantation of faecal microbiota
Authors: D. Barcic, T. Oreskovic, M. Juricevic
Journal: Endoscopy (2024)

Aims C. Difficile is transmitted through the fecal-oral route. Due to the strong resistance of the spores to the physiological conditions of the environment and to alcohol disinfectants, it is important to isolate patients who are infectious or, if this is not possible, to fence them off with a screen. Before the transplantation of fecal microbiota itself, the nurse educates the patient about the transplantation procedure itself and provide them with a sense of security through verbal and non-verbal communication. The aim is to present two methods which we perform in Clinical Hospital Center Rijeka which is a first institution that performed this method in Croatia.
Usefulness of intensifying colonoscopy preparation with macrogol 3350 in patients with prior inadequate bowel preparation
Authors: A. Santos Rodríguez, M. Sierra Morales, P. García Centeno, S. Tabernero Da Veiga
Journal: Endoscopy (2024)

Aims A inadequate bowel preparation is one of the biggest problems in getting a quality colonoscopy. The aim of this study is to evaluate the effectiveness of intesifying bowel preparation with Macrogol 3350 in patients with a previous inadequate bowel preparation.
Accuracy of digital single-operator cholangioscopy for the diagnostic strategy for indeterminate biliary stricture
Authors: C. Gómez Oliva, M. Concepción Martin, J. Szafranska, R. Romito, M. Murzi Pulgar, L. Bordoy Salamanca, C. Guarner Aguilar, M. A. Escorsell Manosa, C. Guarner Argente
Journal: Endoscopy (2024)

Aims Indeterminate biliary strictures diagnosis is challenging despite the availability of high-resolution imaging techniques. A delay in the diagnosis of malignant strictures may lead to a change in prognosis and unnecessary surgery in benign cases ( up to 15-24%). The aim of our study was to determine the usefulness of cholangioscopy to evaluate indeterminate biliary stricture and/or repletion defects suggestive of malignancy. We evaluated weather visual information, with or without pathological anatomy, leads to a change in patient management.
IBD-Disk: A simple tool for correlating disability with mucosal healing and endoscopic activity in inflammatory bowel disease
Authors: H. Kallel, N. Elleuch, R. Limam, W. Dahmeni, A. Hammami, A. Braham, M. Ksiaa, H. Jaziri, A. Ben Slama
Journal: Endoscopy (2024)

Aims The IBD-Disk is a validated 10-question, self-administered visual questionnaire used to assess the inflammatory bowel disease (IBD) related disability. It has been shown that IBD-Disk aligns effectively with the clinical activity reported by either the patient or the practitioner. Nevertheless, only a limited number of studies have investigated its associations with more objective activity scores, such as endoscopic findings.
Cholangioscopy-guided lithotripsy vs. conventional therapy for difficult bile duct stones: An observational cohort study
Authors: D. Kogias, N. Kafalis, G. Kouklakis
Journal: Endoscopy (2024)

Aims Although endoscopic retrograde cholangiopancreatography (ERCP) is the main treatment of common bile duct (CBD) stones, succeeding clearance of the CBD in the majority of cases, the presence of difficult stones can limit its results. Cholangioscopy-guided lithotripsy has recently offered encouraging results in difficult CBD stone removal. Aim of our study was to compare cholangioscopy-guided lithotripsy vs. conventional therapy for difficult bile duct stones treatment.
Successful Technical Approach with Very Low Recurrence Rate after Endoscopic Ultrasound-guided Coils Deployment and Cyanoacrylate Embolization of Gastric Varices: An Eight-year Real World Study
Authors: C. Robles-Medranda, R. Del Valle, M. Egas-Izquierdo, D. Cunto, J. Baquerizo-Burgos, M. Arevalo-Mora, M. Puga-Tejada, F. Ferber-Reyes, J. Alcivar-Vasquez, D. Tabacelia, H. Pitanga-Lukashok
Journal: Endoscopy (2024)

Aims Even though gastric varices (GV) are less frequently encountered than esophageal varices, they are associated with severe bleeding. We aim to target the feeder vessel or afferent component displaying novel therapeutic approach comprising a combined application of cyanoacrylate (CYA) and coils. This approach intended to address the vascular pathology of GV with enhanced precision and efficacy.
Usefulness of a new traction device during endoscopic submucosal dissection of large lesions
Authors: A. Ciccone, E. Brandi
Journal: Endoscopy (2024)

Aims Endoscopic submucosal dissection (ESD) is a fantastic tecnique for resection of advanced gastrointestinal lesions thanks to the possibility of obtaining en bloc resection and achieve histological R0. However, in difficult and large lesions dissection is very challenging and during the procedure you can easily lose the dissection plane and the help of gravity. Traction devices can be useful to make procedure more easy and faster. This study aims to evaluate the efficacy and safety of a novel traction device (ProdiGI Traction Wire, Medtronic) for mantaining the access to the submucosa during the ESD.
An investigation into the materials and life-cycle assessment of supplies commonly used in colonoscopy
Authors: M. García-Castellanos, V. Lorenzo-Zúñiga, S. Gayam, R. Martín-Cabezuelo, G. Vilariño-Ferrer, P. López-Muñoz, I. Tort-Ausina, K. A. Smolen, N. Ayer, A. Vidaurre-Garayo, A. Campillo, V. Pons-Beltrán, H. Pohl
Journal: Endoscopy (2024)

Aims GI endoscopy is highly resource-intensive with a significant environmental impact and extensive utilization of non-reusable plastic instruments. Colonoscopy is the most commonly performed gastrointestinal procedure. The type of material has a direct effect on the environmental impact and on carbon emission. We aimed to scrutinize the materials commonly employed in colonoscopy procedures, assessing their life cycle (LCA) by determining their carbon footprint.
Clinical Significance of Blood Urea Nitrogen as a Predictor of Delayed Bleeding After Endoscopic Submucosal Dissection for Gastric Neoplasm
Authors: B. J. Kim, J. Y. Park, J. G. Kim
Journal: Endoscopy (2024)

Aims Endoscopic submucosal dissection (ESD) is a widely accepted treatment modality for early gastric cancer and gastric adenoma. However, ESD is often accompanied by post-ESD bleeding. Our study aimed to evaluate the predictive value of an elevated blood urea nitrogen (BUN) at 24 hours on delayed bleeding and to assess whether an increase in BUN level is predictive of an artificial gastric ulcer of high-risk Forrest classification during second-look endoscopy after endoscopic submucosal dissection.
Variability in Computer-Aided Detection effect on Adenoma Detection Rate in randomized controlled trials: a meta-regression analysis
Authors: M. Spadaccini, M. Yuichi, C. Hassan, F. Antonio, T. Rizkala, D. Massimi, M. Roberta, H. Patel, K. Kareem, D. Ramai, R. Emanuele, F. Radaelli, A. Fugazza, M. Colombo, D. M. Alessandro, G. franchellucci, D. K. Rex, M. Abdelrahim, B. Pradeep, S. Prateek, A. Repici
Journal: Endoscopy (2024)

Aims The assistance of computer-aided detection (CADe) systems during colonoscopy may increase adenoma detection rate (ADR), theoretically reducing the risk of post-colonoscopy colorectal cancer (PCCRC). Although the promising results in different randomized trials, both the variability of the magnitude of relative effect of CADe systems across the previous studies, and the contradicting results in the first real-life experiences, highlighted a clear gap of knowledge when looking for those factors possibly explaining these fluctuating results. The aim of our analysis was to investigate the different variables possibly affecting the impact of CADe-assisted colonoscopy and its effect on ADR.
Incidence and Characteristics of Endoscopic Gastric Polyps in Patients with Autoimmune Atrophic Gastritis: A Multicentric Retrospective Study
Authors: S. Massironi, C. Gallo, E. Lahner, V. Sciola, F. Cavalcoli, M. V. Lenti, E. Miceli, A. Zilli, L. Dottori, G. De Rossi, B. Annibale, M. Vecchi, P. Cantù, A. Di Sabatino, P. Invernizzi, S. Danese
Journal: Endoscopy (2024)

Aims Gastric polyps arise from the unusual growth of cells in the gastric mucosa. In autoimmune atrophic gastritis (AAG), the gastric mucosa undergoes morphological and functional alterations, as the disease targets parietal cells, leading to a reduction of stomach acid production (hypo-achlorhydria) and to an increase in gastrin (G) levels (hypergastrinemia). These changes, along with the ongoing inflammation, constitute proliferative stimuli on the gastric mucosa. The aims of this study is to investigate the incidence and the characteristics of gastric polyps in patients with overt AAG managed at six tertiary referral centers in Italy.
Safety and Efficacy of Stem cell therapy in Ano perineal Crohn disease : Results of a prospective single centered study
Authors: O. Nacir, F. E. Aharbil, S. Oubaha, K. Krati
Journal: Endoscopy (2024)

Aims The main objective of this study is to evaluate the feasibility and safety of injecting hematopoietic mesenchymal stem cells isolated in patients with CD with a follow up in the Mohamed VI University Hospital for the treatment of ano-perineal fistulas in Crohn's disease. Secondary objectives were to study treatment efficacy and impact on quality of life at week 12 and 48 post-treatment.
Identifying putative genomic biomarkers for risk stratification in Barrett’s esophagus patients with normal histological features
Authors: P. Stougie, N. F. Frei, V. Pappalardo, A. M. Khoshiwal, H. Yu, R. Menezes, L. C. Duits, J. Bergman, M. Stachler
Journal: Endoscopy (2024)

Aims Current surveillance for low-risk Barrett's Esophagus (BE) patients is burdensome, cost-ineffective and dependent on subjective histological assessment of dysplasia with high inter-observer variability. This study aims to identify genomic features that can be identified in a clinically translatable targeted sequencing panel, enhancing the stratification of low-risk BE patients and enabling personalized surveillance strategies.
Characteristics of bowl images predict the quality of colon cleansing before colonoscopy
Authors: L. Amer, N. Kaouk, M. Khanfour, T. Yaacoub, R. Slim, J. Amara, K. Honein, E. Mikhael, S. El Helou, E. Mahfouz, C. Yaghi
Journal: Endoscopy (2024)

Aims The aim of the study was to detect predictors of bowel preparation from the characteristics of toilet bowl images to evaluate bowel preparation before the procedure. This will help in finding innovative solutions to improve the colonic preparation during colonoscopy.
Role of capsule endoscopy and double-balloon enteroscopy in the management of adult patients with coeliac disease and persisting symptoms
Authors: M. G. Shiha, P. Oka, N. Nandi, K. Ingham, S. A. Raju, H. A. Penny, L. Elli, D. S. Sanders, R. Sidhu
Journal: Endoscopy (2024)

Aims Small bowel capsule endoscopy (CE) and double-balloon enteroscopy (DBE) are recommended for the diagnosis and monitoring of patients with nonresponsive or refractory coeliac disease (CD). Previous studies predominantly focused on the efficacy and safety of CE and DBE in this cohort. However, there is a paucity of data regarding the clinical profiles and outcomes of patients undergoing these investigations.
Horseshoe shaped esophageal leiomyoma
Authors: P. Mayer, P. Addeo, L. Héroin, C. Brigand, P. Y. Christamnn
Journal: Endoscopy (2024)

Abstract Text We reported the case of a 30-year-old man, with operated testicular seminoma. An abdominal CT scan, performed before chemotherapy, showed a round shaped, paraoesophageal tumor with a hydroaeric level. The patient had mild grade dysphagia for solid. After chemotherapy, restaging showed regression of retroperitoneal adenopathy but stability of paraoesophageal lesion. Oesogastroduodenal endoscopy was normal. Endoscopic ultrasonography revealed a 45 mm well-limited esophageal lesion, developed from the 4th layer. The lesion was homogeneous and hypoechoic, without calcification. Small vessels were present within the lesion. This appearance suggests a mesenchymal tumor [1]. A 22 Ga needle biopsy was performedand refered to the diagnosis of leiomyoma. Surgical enucleation of the leiomyoma was realised and histology confirm the diagnosis.
Clinical profile of parietal cell dysfunction in multiple gastric neuroendocrine tumors
Authors: M. Watanabe, T. Hirasawa, K. Nakano, S. Shiroma
Journal: Endoscopy (2024)

Aims Parietal cell dysfunction (PCD), a novel disease, has been to cause multiple gastric neuroendocrine tumors (GNETs). In PCD, the proton pump in parietal cells doesn't work well, causing a decrease in gastric acid secretion. This results in an increase in G cells in the pylorus, resulting in hypergastrinemia, which may induce a hyperplastic or neoplastic transformation of the enterochromaffin-like cells in the stomach fundus. Rindi et al. classified GNETs into three types. However, multiple GNETs caused by PCD do not fit into any of the existing types. Reports on PCD remain limited, and its diagnostic criteria remain unestablished. Our institution has managed several cases of PCD with multiple GNETs. This report aims to clarify the clinical characteristics of these cases.
EUS-guided colo-entero-anastomosis with Lumen Apposing Metal Stent (LAMS) as a rescue treatment for malignant bowel occlusions: a multicentre study
Authors: B. Neri, S. Stigliano, D. Biasutto, N. Citterio, A. Lisotti, P. Fusaroli, B. Mangiavillano, G. Donatelli, G. Tonini, F. M. Di Matteo
Journal: Endoscopy (2024)

Aims Malignant bowel obstruction (MBO) is a relevant problem for patients with advanced malignancy. Surgery is the first-choice treatment, however many patients are deemed inoperable. Endoscopic ultrasound (EUS) guided colo-entero-anastomosis with lumen apposing metal stents (LAMS) could represent a new effective palliative treatment option. We aimed to assess the technical success and the safety of EUS guided colo-entero-anastomosis, symptoms relief, time of re-feeding, hospital stay and overall survival.
Malignant polyps without endoscopic cure: is oncological resection mandatory?
Authors: A. I. Ferreira, J. Goncalves, M. Marques Souto, S. Xavier, P. Boal Carvalho, J. Magalhães, J. Cotter
Journal: Endoscopy (2024)

Aims Evaluate the outcomes of patients with malignant polyps without endoscopic cure, who were submitted to surgery, comparing with those who underwent surveillance.
Possibility of ultra-high magnification endoscopy: the tiniest colorectal adenoma ever found
Authors: S. Polishchuk, I. Hornik, A. Lapsar
Journal: Endoscopy (2024)

Abstract Text With years of research and development endoscopy equipment has gone from fiber optic to ultra-high magnification endoscopes with artificial intelligence (AI). It allows endoscopists to detect polyps, especially adenomas at the earliest possible stages. Which leads to a significant increase in adenoma detection rate. A 47 y.o male came in for a screening colonoscopy. In the ascending colon, Paris 0-IIa lesion up to 1mm was visualized with AI assistance. In the narrow-band imaging (NBI) and ultra-high magnification endoscopy the vessel and surface patterns were classified as JNET 2A, pit pattern – Kudo IIIL with only 9 pits involved. An optical diagnosis of tubular adenoma was made and cold forceps polypectomy was performed. Pathology showed tubular adenoma sized 828.8µm, which is, probably, the tiniest adenoma ever found.