A REVIEW OF THE CURRENT STATUS OF THE CHEMOTHERAPY OF TUBERCULOSIS
Authors: W B TUCKER
Journal: Annals of Internal Medicine (1953)

Article1 November 1953A REVIEW OF THE CURRENT STATUS OF THE CHEMOTHERAPY OF TUBERCULOSISWILLIAM B. TUCKER, M.D.WILLIAM B. TUCKER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-39-5-1045 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptNo drug having been thus far found in the treatment of tuberculosis which kills all tubercle bacilli, the objectives of drug treatment in this disease still fall short of the eradication of all infecting organisms. Nevertheless, with greater understanding in recent years of the pathology of the disease, made possible largely by advances in thoracic surgery, it is now possible to state our clinical objectives more accurately.It has been found1that in pulmonary tuberculosis treated effectively with drugs for adequate periods there is little remaining reversible disease (lobular pneumonitis and tubercles without necrosis), and that the principal remaining components...Bibliography1. Medlar EM: Basic pathologic concepts, in Symposium on the treatment of pulmonary tuberculosis, Transactions of the National Tuberculosis Association, 1951, pp. 245-248. Google Scholar2. LongFerebee ERSH: A controlled investigation of streptomycin treatment in pulmonary tuberculosis, Pub. Health Rep. 65: 1419-1451 (Nov. 3) 1950. CrossrefMedlineGoogle Scholar3. Tucker WB: A controlled study of the variables in the chemotherapy of pulmonary tuberculosis, Transactions of the Twelfth Conference on the Chemotherapy of Tuberculosis, Feb. 9-12, 1953, Veterans Administration, Washington, D. C. Google Scholar4. LyghtHawkins CEJE a. : Streptomycin and dihydrostreptomycin in the treatment of tuberculosis: a comparative study, Transactions of the Twelfth Conference on the Chemotherapy of Tuberculosis. b. Cohen, S. S., Johnsen, L., Lichtenstein, M. R., and Lynch, W. J.: A comparative study of streptomycin and dihydrostreptomycin in pulmonary tuberculosis, Am. Rev. Tuberc. 68: 229-237, 1953. c. Mahady, S. C. F., Armstrong, F. L., Beck, F., Horton, R., and Lincoln, N. S.: A comparative study of streptomycin and dihydrostreptomycin in pulmonary tuberculosis, ibid. 68: 238-248, 1953. Google Scholar5. Tables on toxicity, Transactions of the Eleventh Conference on the Chemotherapy of Tuberculosis, Jan. 17-20, 1952, Veterans Administration, Washington, D. 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C., October, 1952; and Hobby, G.: Present status of viomycin therapy, Transactions of the Twelfth Conference on the Chemotherapy of Tuberculosis, Feb. 9-12, 1953, Veterans Administration, Washington, D. C. Google Scholar19. WarringHowlett FCKS: Allergic reactions to para-aminosalicylic acid. Report of seven cases, including one case of Löffler's syndrome, Am. Rev. Tuberc. 65: 235-249, 1952. MedlineGoogle Scholar20. MillerSandsWalkerDyeTempel FLJJRWECW: Combined daily terramycin and intermittent streptomycin in the treatment of pulmonary tuberculosis, Am. Rev. Tuberc. 66: 534-541, 1952. MedlineGoogle Scholar21. Dubos RJ: Discussion on treatment of tuberculous meningitis and survival of bacilli in tuberculous lesions, Transactions of the Eleventh Conference on the Chemotherapy of Tuberculosis, 1952; and Am. Rev. Tuberc. 65: 637-640, 1952. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *From the Symposium on Tuberculosis presented at the Thirty-Fourth Annual Session of the American College of Physicians, Atlantic City, New Jersey, April 15, 1953.From the Tuberculosis Service, Veterans Administration Hospital, and the Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAcademic Medical Centers and the U.S. Department of Veterans Affairs: A 75-Year Partnership Influences Medical Education, Scientific Discovery, and Clinical CareExperimental Chemotherapy of Tuberculosis and Other Mycobacterial InfectionsTreatment of tuberculosisEmergence of Antibiotic-Resistant BacteriaMICROBIAL RESISTANCE TO ANTIBIOTICS*†MARK H. LEPPER, M.D.Present status of the chemotherapy of tuberculosisTuberculosisCurrent Concepts in the Treatment of Pulmonary TuberculosisCurrent Status of Chemotherapy of Tuberculosis 1 November 1953Volume 39, Issue 5Page: 1045-1061KeywordsClinical pathologyDrugsFallsHospital medicineInfectious diseasesNecrosisPneumonitisPulmonary diseasesThoracic surgeryTuberculosis ePublished: 1 December 2008 Issue Published: 1 November 1953 PDF downloadLoading ...