Psoriasis
Authors: Rita V. Patel, Mark Lebwohl
Journal: Annals of Internal Medicine (2011)

In the Clinic2 August 2011PsoriasisDeborah Cotton, MD, MPH, Darren Taichman, MD, PhD, Sankey Williams, MD, Rita V. Patel, MD, and Mark Lebwohl, MDDeborah Cotton, MD, MPHSearch for more papers by this author, Darren Taichman, MD, PhDSearch for more papers by this author, Sankey Williams, MDSearch for more papers by this author, Rita V. Patel, MDSearch for more papers by this author, and Mark Lebwohl, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-155-3-201108020-01002 SectionsSupplemental MaterialAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Psoriasis affects 2% to 3% of American adults. A study of nearly 1700 adults with a dermatologist-confirmed diagnosis of psoriasis found the overall annual sex- and age-adjusted incidence rate to be 62.3 of 100 000 people over a 30-year period (95% CI, 58.8 to 65.8). The annual incidence of psoriasis almost doubled between the 1970s and 2000 (50.8 to 100.5 per 100,000 people; P = 0.001), possibly reflecting increased exposure to risk factors or changes in diagnosing patterns in this population (1).Approximately 40% of patients with psoriasis or psoriatic arthritis (PsA) have a family history of these disorders among ...References1. Icen M, Crowson CS, McEvoy MT, Dann FJ, Gabriel SE, Maradit Kremers H. Trends in incidence of adult-onset psoriasis over three decades: a population-based study. J Am Acad Dermatol. 2009;60:394-401. [PMID:19231638] Google Scholar2. Elder JT, Bruce AT, Gudjonsson JE, et al. Molecular dissection of psoriasis: integrating genetics and biology. J Invest Dermatol. 2010;130:1213-26. [PMID:19812592] Google Scholar3. Neimann AL, Porter SB, Gelfand JM. The epidemiology of psoriasis. Expert Rev Dermatol 2006;1:63-75. Google Scholar4. Rapp SR, Feldman SR, Exum ML, Fleischer AB Jr, Reboussin DM. 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