The Reaction to Nitrites in the Anginal Syndrome and Arterial Hypertension
Authors: Alex M. Burgess
Journal: Annals of Internal Medicine (1931)

Article1 October 1931The Reaction to Nitrites in the Anginal Syndrome and Arterial HypertensionALEX M. BURGESS, M.D., F.A.C.P.ALEX M. BURGESS, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-5-4-441 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the introduction of the use of amyl nitrite by Sir Lauder Brunton in 1867 nothing has been found to excel the nitrites for the relief of the pain in angina pectoris. Although the pharmacology of the members of this group has been exhaustively studied the question as to the mode of their action in anginal pain has never been definitely settled. This is due partly to the fact that the cause of the pain has not been thoroughly understood. Furthermore, because of their known action on the walls of the peripheral arterioles resulting in a lowering of blood pressure,...References1 STEIGLITZ EJ: Arterial hypertension: evaluation of the prognosis, Arch. Int. Med., 1930, xlvi, 227. CrossrefGoogle Scholar2 WALLACERINGER : The lowering of blood pressure by the nitrite group, Jr. Am. Med. Assoc., 1909, liii, 1629. CrossrefGoogle Scholar3 STEIGLITZ EJ: Loc. cit. Google Scholar4 LEAKELOEVENHARTMUEHLBERGER CDAS: Dilation of cerebral vessels as a factor in headache, Jr. Am. Med. Assoc., 1927, lxxxviii, 1076. CrossrefGoogle Scholar5 RAPHAELSTANTON TJM: Action of certain drugs on brain circulation in man. Arch. Neurol. and Psych., 1919, ii, 389. CrossrefGoogle Scholar6 MACHT DI: Action of nitrites on the isolated surviving pulmonary artery, Jr. Am. Med. Assoc., 1914, lxii, 525. Google Scholar7 VOEGTLINMACHT CDI: Jr. Pharm. and Exper. Therap., 1913, v, 77. Google Scholar8 SCHLOSS K: Deutsch. Arch. f. klin. Med., 1913, cxi, 310. Google Scholar9 LOEB O: Arch. f. exp. Path. u. Pharm., 1903, li, 64. CrossrefGoogle Scholar10 SMITH FM: The action of the nitrites on the coronary circulation, Arch. Int. Med., 1921, xxviii, 836. CrossrefGoogle Scholar11 KEEFERRESNIK CSWH: Angina pectoris: a syndrome caused by anoxemia of the myocardium, Arch. Int. Med., 1928, xli, 769. CrossrefGoogle Scholar12 MAY H: Die "Arbeits-reaktion" des Blutdruckes bei Gesunden und Kreislaufkranken und ihr Zusammenhang mit der Angina Pectoris, Med. Klin., 1928, xxiv, 1704. Google Scholar13 AYMAN D: Normal blood pressure in essential hypertension. Jr. Am. Med. Assoc., 1930, xciv, 1214. CrossrefGoogle Scholar14 BROOKS H: Concerning certain phases of angina pectoris, Internat. Clinics, 1928, iv, 12-32. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Providence, R. I.*Presented at the Baltimore Meeting of the American College of Physicians, March 24, 1931. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe effect of aspirin on the hemodynamic response to nitroglycerinCirculatory changes during the pain of angina pectorisCirculatory changes associated with spontaneous angina pectorisRelationship between Arterial Pressure and Exertional Angina Pectoris in Hypertensive PatientsInositol and Mannitol Hexanitrates in Hypertension ManagementTHE DRUG TREATMENT OF HYPERPIESIAThe relation of the systolic blood pressure and heart rate to attacks of angina pectoris precipitated by effortObservations on arterial blood pressure during attacks of angina pectorisDie Klinik der Coronarerkrankungen 1 October 1931Volume 5, Issue 4Page: 441-462KeywordsAnginaArteriolesBlood pressureHypertensionPharmacology ePublished: 1 December 2008 Issue Published: 1 October 1931 PDF downloadLoading ...