tbuckley/cabot-search huggingface dataset:
Combining CRISPR-Cas9 and TCR exchange to generate a safe and efficient cord blood-derived T cell product for pediatric relapsed AML
Authors: Vania Lo Presti, Angelo Meringa, Ester Dunnebach, Alice van Velzen, Aida Valera Moreira, Ronald W Stam, Rishi S Kotecha, Anja Krippner-Heidenreich, Olaf T Heidenreich, Maud Plantinga, Annelisa Cornel, Zsolt Sebestyen, Jurgen Kuball, Niek P van Til, S Nierkens
Journal: Journal for ImmunoTherapy of Cancer (2024)

Background Hematopoietic cell transplantation (HCT) is an effective treatment for pediatric patients with high-risk, refractory, or relapsed acute myeloid leukemia (AML). However, a large proportion of transplanted patients eventually die due to relapse. To improve overall survival, we propose a combined strategy based on cord blood (CB)-HCT with the application of AML-specific T cell receptor (TCR)-engineered T cell therapy derived from the same CB graft. Methods We produced CB-CD8 + T cells expressing a recombinant TCR (rTCR) against Wilms tumor 1 (WT1) while lacking endogenous TCR (eTCR) expression to avoid mispairing and competition. CRISPR-Cas9 multiplexing was used to target the constant region of the endogenous TCRα ( TRAC ) and TCRβ ( TRBC ) chains. Next, an optimized method for lentiviral transduction was used to introduce recombinant WT1-TCR. The cytotoxic and migration capacity of the product was evaluated in coculture assays for both cell lines and primary pediatric AML blasts. Results The gene editing and transduction procedures achieved high efficiency, with up to 95% of cells lacking eTCR and over 70% of T cells expressing rWT1-TCR. WT1-TCR-engineered T cells lacking the expression of their eTCR (eTCR −/− WT1-TCR) showed increased cell surface expression of the rTCR and production of cytotoxic cytokines, such as granzyme A and B, perforin, interferon-γ (IFNγ), and tumor necrosis factor-α (TNFα), on antigen recognition when compared with WT1-TCR-engineered T cells still expressing their eTCR (eTCR +/+ WT1-TCR). CRISPR-Cas9 editing did not affect immunophenotypic characteristics or T cell activation and did not induce increased expression of inhibitory molecules. eTCR −/− WT1-TCR CD8 + CB-T cells showed effective migratory and killing capacity in cocultures with neoplastic cell lines and primary AML blasts, but did not show toxicity toward healthy cells. Conclusions In summary, we show the feasibility of developing a potent CB-derived CD8 + T cell product targeting WT1, providing an option for post-transplant allogeneic immune cell therapy or as an off-the-shelf product, to prevent relapse and improve the clinical outcome of children with AML.
Enhanced mitochondrial fusion during a critical period of synaptic plasticity in adult-born neurons
Authors: Sandra M.V. Kochan, Meret Cepero Malo, Milica Jevtic, Hannah M. Jahn-Kelleter, Gulzar A. Wani, Kristiano Ndoci, Laura Pérez-Revuelta, Felix Gaedke, Iris Schäffner, Dieter Chichung Lie, Astrid Schauss, Matteo Bergami
Journal: Neuron (2024)

Integration of new neurons into adult hippocampal circuits is a process coordinated by local and long-range synaptic inputs. To achieve stable integration and uniquely contribute to hippocampal function, immature neurons are endowed with a critical period of heightened synaptic plasticity, yet it remains unclear which mechanisms sustain this form of plasticity during neuronal maturation. We found that as new neurons enter their critical period, a transient surge in fusion dynamics stabilizes elongated mitochondrial morphologies in dendrites to fuel synaptic plasticity. Conditional ablation of fusion dynamics to prevent mitochondrial elongation selectively impaired spine plasticity and synaptic potentiation, disrupting neuronal competition for stable circuit integration, ultimately leading to decreased survival. Despite profuse mitochondrial fragmentation, manipulation of competition dynamics was sufficient to restore neuronal survival but left neurons poorly responsive to experience at the circuit level. Thus, by enabling synaptic plasticity during the critical period, mitochondrial fusion facilitates circuit remodeling by adult-born neurons.
Preclinical development of novel PD-L1 tracers and first-in-human study of [<sup>68</sup>Ga]Ga-NOTA-RW102 in patients with lung cancers
Authors: You Zhang, Min Cao, Yanfei Wu, Sara Malih, Dong Xu, Erpeng Yang, Muhsin H Younis, Wilson Lin, Haitao Zhao, Cheng Wang, Qiufang Liu, Jonathan W Engle, Mohammad J Rasaee, Yihui Guan, Gang Huang, Jianjun Liu, Weibo Cai, Fang Xie, Weijun Wei
Journal: Journal for ImmunoTherapy of Cancer (2024)

Background The programmed cell death protein-1 (PD-1)/programmed death receptor ligand 1 (PD-L1) axis critically facilitates cancer cells’ immune evasion. Antibody therapeutics targeting the PD-1/PD-L1 axis have shown remarkable efficacy in various tumors. Immuno-positron emission tomography (ImmunoPET) imaging of PD-L1 expression may help reshape solid tumors’ immunotherapy landscape. Methods By immunizing an alpaca with recombinant human PD-L1, three clones of the v ariable domain of the h eavy chain of h eavy-chain only antibody (VHH) were screened, and RW102 with high binding affinity was selected for further studies. ABDRW102, a VHH derivative, was further engineered by fusing RW102 with the albumin binder ABD035. Based on the two targeting vectors, four PD-L1-specific tracers ([ 68 Ga]Ga-NOTA-RW102, [ 68 Ga]Ga-NOTA-ABDRW102, [ 64 Cu]Cu-NOTA-ABDRW102, and [ 89 Zr]Zr-DFO-ABDRW102) with different circulation times were developed. The diagnostic efficacies were thoroughly evaluated in preclinical solid tumor models, followed by a first-in-human translational investigation of [ 68 Ga]Ga-NOTA-RW102 in patients with non-small cell lung cancer (NSCLC). Results While RW102 has a high binding affinity to PD-L1 with an excellent K D value of 15.29 pM, ABDRW102 simultaneously binds to human PD-L1 and human serum albumin with an excellent K D value of 3.71 pM and 3.38 pM, respectively. Radiotracers derived from RW102 and ABDRW102 have different in vivo circulation times. In preclinical studies, [ 68 Ga]Ga-NOTA-RW102 immunoPET imaging allowed same-day annotation of differential PD-L1 expression with specificity, while [ 64 Cu]Cu-NOTA-ABDRW102 and [ 89 Zr]Zr-DFO-ABDRW102 enabled longitudinal visualization of PD-L1. More importantly, a pilot clinical trial shows the safety and diagnostic value of [ 68 Ga]Ga-NOTA-RW102 immunoPET imaging in patients with NSCLCs and its potential to predict immune-related adverse effects following PD-L1-targeted immunotherapies. Conclusions We developed and validated a series of PD-L1-targeted tracers. Initial preclinical and clinical evidence indicates that immunoPET imaging with [ 68 Ga]Ga-NOTA-RW102 holds promise in visualizing differential PD-L1 expression, selecting patients for PD-L1-targeted immunotherapies, and monitoring immune-related adverse effects in patients receiving PD-L1-targeted treatments. Trial registration number NCT06165874 .
A BURNING HEART: A UNIQUE CASE OF MYOCARDITIS AS THE INITIAL MANIFESTATION OF SYSTEMIC LUPUS ERYTHEMATOSUS
Authors: Thomas I. Minik, Andrew H. Nguyen, Mariyam Sheidu, Madelyn Hurwitz, Allman Rollins, Abbas Emaminia, Ahmad Abdul-Aziz
Journal: Journal of the American College of Cardiology (2024)
STENTED FENESTRATION APPROACH WITH ATRIAL SEPTAL DEFECT DEVICE CLOSURE IN SEVERE PULMONARY HYPERTENSION
Authors: Mohan Satish, Nickpreet Singh, Su Yuan, Shmuel Chen, Mark Reisman, Luke Kim, Dmitriy N. Feldman, Shing-Chiu Wong, Geoffrey Bergman, Evelyn M. Horn, Maria G. Karas, Harsimran S. Singh
Journal: Journal of the American College of Cardiology (2024)
TNNT2 AND SCN5A SIMULTANEOUS MUTATIONS: A CASE OF FAMILIAL DILATED CARDIOMYOPATHY
Authors: Alberto Santiago Hernández, Eder Gonzalez-Macedo, Alejandro Ezquerra, Manuel Alejandro Candia Ramirez, Lilia Hernandez Bravo, Maryuri Chumbes Aguirre, Sergio Patrón-Chi, Ximena Latapi Ruiz Esparza, Nila Papaqui-Quitl, Amada Alvarez-Sangabriel, Antonio Jordan-Rios, Juan Carlos De la Fuente Mancera, Braiana Ángeles Díaz Herrera, Diego Araiza Garaygordobil, Alexandra Arias-Mendoza, Carlos Alberto Guízar
Journal: Journal of the American College of Cardiology (2024)
HYPERTENSION-DRIVEN ANGINA UNVEILING ANOMALOUS ORIGIN AND MALIGNANT COURSE OF RIGHT CORONARY ARTERY: A CASE REPORT
Authors: Sanjay Pujar, Sridevi Reddy Pitta, Mandvi Pandey, Anum Mubasher, Ana Chavez Velasquez
Journal: Journal of the American College of Cardiology (2024)
AN INSIDIOUS PATH TO THE DIAGNOSIS OF AL CARDIAC AMYLOIDOSIS
Authors: Heather Rose, Lauren Powell, Viswajith Nambiar, Manisha Bhutani, Jai Singh, Theodore A. Frank, Carol Weida, Amar Parikh, Gautam Phadke, Urvi Desai, Baha Moshiree, Nicole B. Cyrille-Superville
Journal: Journal of the American College of Cardiology (2024)
UNCONVENTIONAL MANAGEMENT OF RARE OSTIAL CALCIFIC STENOSIS IN LEFT INTERNAL MAMMARY ARTERY GRAFT: A NOTEWORTHY CASE
Authors: Siddharth Bajaj, Niyati Grewal, Abimbola Balogun, Prafulla P. Mehrotra, Urooj Fatima
Journal: Journal of the American College of Cardiology (2024)
FROM GAINS TO STRAINS: A CASE OF ANABOLIC STEROID INDUCED MYOCARDITIS
Authors: Jose Antonio Luna Alvarez Amezquita, Victor G. Becerra-Gonzales, Moises Abraham Vasquez Martinez, Mina Iskander, Juan Andres Quintero-Martinez, Ivan Alfredo Mijares Rojas, Hoda Butrous
Journal: Journal of the American College of Cardiology (2024)
CARDIAC RETRANSPLANTATION IN A PEDIATRIC PATIENT WITH SEVERE CORONARY ALLOGRAFT VASCULOPATHY
Authors: Lane A. McLendon, Dipankar Gupta, Fredrick Jay Fricker, Biagio A. Pietra, Renata L. Shih, Haley Blanchette, Emily Martin, Jennifer Rackley, John Anthony Coppola
Journal: Journal of the American College of Cardiology (2024)
GRADE 3 MYOCARDIAL UPTAKE ON 99M-TECHNETIUM PYROPHOSPHATE SCAN IN A PATIENT WITH MULTIPLE MYELOMA AND LIGHT CHAIN AMYLOIDOSIS
Authors: Kanishka Uttam Chandani, Maharshi Raval, Ahmed Nadeem, Fadi Al Bilbeisi, Walid D. Saber, Ibrahim ElGabry
Journal: Journal of the American College of Cardiology (2024)
FROM SORE TO CORE: A CASE OF NON-RHEUMATIC STREPTOCOCCAL MYOPERICARDITIS
Authors: Sacide S. Ozgur, Nida Ansari, Alan Alcantara, Yezin F. Shamoon, Sherif Elkattawy, Rachel Abboud, Rajkumar Doshi, Fayez E. Shamoon
Journal: Journal of the American College of Cardiology (2024)
CARDIOCEREBRAL CASCADE: A CASE OF TAKOTSUBO CARDIOMYOPATHY AND POSTERIOR REVERSIBLE ENCEPHALOPATHY SYNDROME FOLLOWING METHADONE WITHDRAWAL
Authors: Sacide S. Ozgur, Maria Perez, Yezin F. Shamoon, Sherif Elkattawy, Sindhura Ananthaneni, Rachel Abboud, Fayez E. Shamoon
Journal: Journal of the American College of Cardiology (2024)
DOUBLE TROUBLE: A CASE OF SUPERIMPOSED TRANSTHYRETIN AMYLOID CARDIOMYOPATHY (ATTR-CM) IN A PATIENT WITH ESTABLISHED HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY (HOCM)
Authors: Veronika Steingauer, Elias Akiki, Muhannad Abbasi, Edward El-Am, Ali Ahmad, Alexander Bratt, Reto Kurmann, Kyle W. Klarich
Journal: Journal of the American College of Cardiology (2024)
AVENGERS ASSEMBLE! THE HEART TEAM VS. ANOMALOUS CORONARY REVASCULARIZATION
Authors: Christina Romano, Cara Joseph, Gabrielle Rhinehart, Hata Mujadzic, Ninad M. Zaman, William Meeks, Rebecca Kocak, Muhammad Mohyuddin, Meer Fakhry
Journal: Journal of the American College of Cardiology (2024)
SPONTANOUS BIATRIAL THROMBI AS INITIAL PRESENTATION OF MYELOMA AND SUSPECTED CARDIAC AMYLOIDOSIS
Authors: Radhika Deshpande, Sriviji Senthil Kumaran, Pablo Barzallo, Chetan Bhardwaj, Vijayasree Paleru, Kavitha Kalvakuri
Journal: Journal of the American College of Cardiology (2024)
HEART'S FIGHT BACK - BATTLING SEVERE CARDIOMYOPATHY UNVEILED BY MYXEDEMA COMA AFTER MISCARRIAGE IN A YOUNG WOMAN
Authors: Tala Altarawneh, SHADEN DALOUB, Adee Elhamdani, Kanaan Mansoor, Carlos Alberto Rueda Rios
Journal: Journal of the American College of Cardiology (2024)
A RARE CASE OF NON-BACTERIAL THROMBOTIC ENDOCARDITIS IN A PATIENT WITH KNOWN ITP AND NEWLY DIAGNOSED ANTIPHOSPHOLIPID SYNDROME AFTER PRESENTING WITH A STROKE
Authors: Yaakov Spira, Swati Chand, Kassidy Veasaw, Uzair Mahmood, Anthon Fuisz
Journal: Journal of the American College of Cardiology (2024)
LONG-TERM COMPLICATIONS OF ATRIAL SWITCH OPERATION IN PATIENT WITH TRANSPOSITION OF THE GREAT VESSELS
Authors: Thaissa Monteiro, Beny Binensztok, Aloan Carlos Lemos Ferraz, Cíntia Mattoso, Nathalia Valle, Maria Carolina Terra Cola, Bianca De Almeida Teodoro, Maria Gabriela Pimenta Dos Santos, David Duarte, Lorreine Ferreira, Luiza Nobre, Regis Oliveira, adriana MACINTYRE innocenzi, Fabio Akio Nishijuka
Journal: Journal of the American College of Cardiology (2024)
A DIAGNOSTIC CONUNDRUM: VENTRICULAR FIBRILLATION CARDIAC ARREST IN A YOUNG WOMAN
Authors: Miguel Belaunzaran, Yasmeen Taha, Joshua Latner, Sujay Kamisetty, Mohammad Al-Ani, Ralph Matar, Thomas J. Lewandowski, Ellen Kelley, Michael Massoomi
Journal: Journal of the American College of Cardiology (2024)
PERICARDIAL EFFUSION, HYPOTHYROIDSIM AND PREGNANCY-A POTENTIALLY DANGEROUS DYNAMIC TRIO
Authors: Ro-Kaye A. Simmonds, Manisha Singam, Maria Fariduddin, Taryn Heyman, Yuval Eisenberg, Aswathi Jayaram, Joan E. Briller
Journal: Journal of the American College of Cardiology (2024)
A SILENT MENACE: REPORT OF A FATAL PAPILLARY FIBROELASTOMA
Authors: Braiana Ángeles Díaz Herrera, Eder Jonathan Amaro Palomo, Alejandro Ezquerra, Oscar-Ulises Preciado-Gutierrez, Sarai Hernandez Pastrana, Erika Elizabet Jaime Borja, Jorge Garcia Espinosa, Rafael Sanez, Alejandro Sierra, Daniel Sierra, Rodrigo GoparNieto, Jose Luis Briseño De La Cruz, Hector Gonzalez-Pacheco, Diego Araiza Garaygordobil, Alexandra Arias-Mendoza
Journal: Journal of the American College of Cardiology (2024)
STENT OR SURGERY: THE UTILIZATION OF INNER-BRANCH ENDOVASCULAR ANEURYSM REPAIR AS AN ALTERNATIVE TO OPEN SURGERY IN A PATIENT WITH HOSTILE VASCULAR ANATOMY
Authors: Anas I. Zaqut, Mahmoud Odeh, Rawan Almejaibal, Leen Alhadidi, Tareq Massimi
Journal: Journal of the American College of Cardiology (2024)
HYDRALAZINE-INDUCED ANTINEUTROPHILIC CYTOPLASMIC ANTIBODY (ANCA)-ASSOCIATED VASCULITIS: A RARE ENTITY
Authors: Nimesh Khanal, Kristina Shum, Prem Parajuli, Bidhya Timilsina, Bharosha Bhattarai, Aniruddha Singh
Journal: Journal of the American College of Cardiology (2024)
AORTOMITRAL INTERVALVULAR FIBROSA PSEUDO-ANEURYSM WITH FISTULA INTO AORTIC ROOT AS A COMPLICATION OF SEVERE INFECTIVE ENDOCARDITIS
Authors: Naser Yamani, Fadi Khoury, Jake Hillyer, Billal Mohmand, Ryan C. Oeltgen
Journal: Journal of the American College of Cardiology (2024)
ASYMPTOMATIC AORTIC DISSECTION: AN UNFORESEEN CATASTROPHE
Authors: Stephanie Ortiz-Troche, Porfirio E. Diaz-Rodriguez, Juan Vazquez-Fuster, Victor H. Molina-Lopez, Alejandro Loyola-Vélez, Luis Muniz-Camacho, Jose J. Acevedo
Journal: Journal of the American College of Cardiology (2024)
INTRACARDIAC BLOOD CYST INVOLVING BASAL VENTRICULAR SEPTUM WITH MEMBRANOUS VSD, RARE PRESENTATION
Authors: Talha Bin Farooq, Krishna Prasad Kurpad, Muhammad Umair Rana, Muhammad Hasib Khalil, Yousra Khalid, Osama Alsara, Sanjay Mehta
Journal: Journal of the American College of Cardiology (2024)
A CASE OF FULMINANT NATIVE QUADRIVALVULAR ENDOCARDITIS WITH ROOT ABSCESS AND BILATERAL CEREBELLAR AND CEREBRAL INFARCTS SECONDARY TO AEROCOCCUS URINAE
Authors: Rachel A. Beaupre, Saliha Erdem, Amrit Kanwar, Mohammed M. Uddin, Mishita Goel, Luis C. Afonso
Journal: Journal of the American College of Cardiology (2024)
PE-EK A BOO: WHEN PE IS NOT REALLY PE - AORTIC DISSECTION WITH HEMATOMA MASQUERADING AS PULMONARY EMBOLISM
Authors: Juan Bello, Yong Lee, Navid Radfar, Afif Hossain, Kirsys Guerrero, Jeffrey S. Lander
Journal: Journal of the American College of Cardiology (2024)
ATTR AMYLOIDOSIS GRADUAL PROGRESSION OVER 15 YEARS DETECTED ON DIASTOLOGY AND SPECKLE TRACKING STRAIN; ATTENTION TO THE “RED FLAGS”
Authors: Abdel Hadi El Hajjar, Alveena Batool Syed, Pradeep V. Kandula, Aqieda Bayat, Tiffany Dong, Wael A. Jaber, Allan L. Klein
Journal: Journal of the American College of Cardiology (2024)
RE-EVALUATING EXERTIONAL DYSPNEA IN A YOUNG PATIENT WITH RESTRICTIVE VENTRICULAR SEPTAL DEFECT
Authors: Leila Haghighat, Joseph Bayne, Christopher Lee, Mina Khorashadi, Ayesha Salahuddin, Harsh Agrawal, Peter Kouretas, Ramin E. Beygui, Elyse Foster, Aarthi Sabanayagam
Journal: Journal of the American College of Cardiology (2024)
THE ROLE OF MULTIMODAL IMAGING IN DIAGNOSING A CASE OF ATRIAL MYXOMA WITH PATENT FORAMEN OVALE
Authors: Amir Joshi, Gayatri Narayan, Vidit Majmundar, Kannu Bansal, Ajay Mishra, Nitish Sharma, Michelle L. Hadley
Journal: Journal of the American College of Cardiology (2024)
USE OF INTRA-OPERATIVE TRANSESOPHAGEAL ECHOCARDIOGRAPHY IN DIAGNOSIS OF PAPILLARY MUSCLE RUPTURE FOLLOWING NON-ST ELEVATION MYOCARDIAL INFARCTION
Authors: Varun Subashchandran, Edward Yang, Srisha Kotlo, Juan Ignacio Cotella, Jeremy Slivnick
Journal: Journal of the American College of Cardiology (2024)
ARSENIC EXPOSURE AND RECURRENT PERICARDITIS IN ACUTE PROMYELOCYTIC LEUKEMIA: HOW RILONACEPT CHANGES THE GAME
Authors: Abdel Hadi El Hajjar, Zachary S. Yaker, Alveena Batool Syed, Akiva Rosenzveig, Aqieda Bayat, Pradeep V. Kandula, Allan L. Klein
Journal: Journal of the American College of Cardiology (2024)
PAPILLARY FIBROELASTOMA OF THE RIGHT CORONARY ARTERY LEAFLET OF AORTIC VALVE PRESENTING AS ACUTE CORONARY SYNDROME
Authors: Haris Muhammad, Oghenetejiri Gbegbaje, Elliot Wiesenfeld, Andrew Weissman, Jennifer C. Wellings, Aron I. Schwarcz, Justin Adam Karl, Molly Schultheis
Journal: Journal of the American College of Cardiology (2024)
A NOVEL USE FOR INTERLEUKIN-1 INHIBITORS: TRANSIENT EFFUSIVE CONSTRICTIVE PERICARDITIS
Authors: Zachary S. Yaker, Muhammad Majid, Alveena Batool Syed, Aro Daniela Arockiam, Aqieda Bayat, Ushasi Saraswati, Jaideep Singh Bhalla, Tom Kai Ming Wang, Allan L. Klein
Journal: Journal of the American College of Cardiology (2024)
BOSUTINIB'S DOUBLE TROUBLE: UNUSUAL PLEURAL EFFUSION AND CARDIAC TAMPONADE IN CML
Authors: Rand Sabanci, Manel Boumegouas, Moiz Saeed, Khalid Saeed Al-Asad, Andrew G. Kim, Kevin Watat, Gabriel Panama, Adolfo Martinez, Majid Yavari, Niket Shah, Jason Law, Qi Xuan Ang, George S. Abela
Journal: Journal of the American College of Cardiology (2024)
STREPTOCOCCUS CONSTELLATUS PURULENT PERICARDITIS PRESENTING AS SEPTIC SHOCK
Authors: Muhammad Hasib Khalil, Krishna Prasad Kurpad, Mobeen Z. Haider, Muhammad Umair Rana, Talha Bin Farooq, Sanjay S. Mehta, Naveed A. Adoni
Journal: Journal of the American College of Cardiology (2024)
A PICKLEBALL PLAYER WITH CHRONIC IDIOPATHIC RECURRENT PERICARDITIS TREATED WITH LONG-TERM IL-1 RECEPTOR ANTAGONIST THERAPY
Authors: Pradeep V. Kandula, Aqieda Bayat, Abdel Hadi El Hajjar, Alveena Batool Syed, Devora Lichtman, Allan L. Klein
Journal: Journal of the American College of Cardiology (2024)
LOEFFLER'S ENDOCARDITIS AND HYPEREOSINOPHILIC SYNDROME IN CHIC2 LOCUS DELETION
Authors: Andrew Takla, Nada Hafez, Hina Ukrani, Astha Prasai, Asmaa Ahmed, Omofolarin Babayale, Kirolus Sourial, Bipul Baibhav
Journal: Journal of the American College of Cardiology (2024)
PROSTHETIC AORTIC VALVE DEHISCENCE: A MULTIMODALITY IMAGING DIAGNOSIS IN AN ASYMPTOMATIC CARDIAC SURGICAL PATIENT
Authors: José Martín Alanís Naranjo, Kevin David Aragón Ontiveros, Angelica Guerrero González, Omar Alejandro Gil Guzmán, Julio Cesar Rivera Hermosillo, Diana Carolina Mendez Tino, Cielmar Galeana
Journal: Journal of the American College of Cardiology (2024)
EUSTACHIAN VALVE ENDOCARDITIS CAUSED BY STAPHYLOCOCCUS PETTENKOFERI &amp; COMPLICATED BY DRESS SYNDROME: A RARE CASE REPORT
Authors: Karan Chhabra, Sam Alsabti, Nishaki Mehta, Carl Lauter, Simon R. Dixon, Carmen Demarco
Journal: Journal of the American College of Cardiology (2024)
IMPROVEMENT OF TRICUSPID REGURGITATION BY INCREASING PACEMAKER BASELINE HEART RATE IN THE SETTING OF ACUTE RIGHT VENTRICULAR FAILURE AND DILATATION
Authors: Priyanka Bhagat-Raj, Anisha Pareddy, Abdalaziz Awadelkarim, John Dayco, Luis C. Afonso, Tiffany T. Le, Fadi Kathawa, Parnal Kapadia
Journal: Journal of the American College of Cardiology (2024)
REFRACTORY UNSTABLE SUPRAVNTRICULAR TACHYCARDIA REVERTED TO SINUS RHYTHM WITH RAPID SEQUENCE INDUCTION AND INTUBATION
Authors: Mohamad Talal Basrak, Mohamed Eid, Hussam Elmelliti, Muhammad Firas Alhammad, Khaled Ferih, Asad Ismail Abusweireh, Mhd Baraa Habib
Journal: Journal of the American College of Cardiology (2024)
ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY CARRIER WITH EMBOLIC STROKE
Authors: Anmol Johal, Allen Fooks, Anton Mararenko, Helen Pozdniakova, Mohammed Abdila, Ndausung Udongwo, Christopher P. Austin, Eran Zacks, Nidhi Tripathi, Yanting Wang
Journal: Journal of the American College of Cardiology (2024)
ISOLATED CARDIAC SARCOIDOSIS. CLINICAL PRESENTATION, DIAGNOSIS AND TREATMENT OF A CASE
Authors: Estela Isabel Carvajal Juarez, Erick Alexanderson Rosas, Gabriela Meléndez Ramírez, Sergio Patrón-Chi, Aloha Meave, María Guadalupe Contreras Peña, Maryuri Chumbes Aguirre, Jesus Hernandez, Leonardo Proaño-Bernal, Raul Velazquez, Luis Enrique González Feria
Journal: Journal of the American College of Cardiology (2024)
CONNECTING THE DOTS: HEMOCHROMATOSIS, DESMOGLEIN-2 GENE MUTATION, AND ARRHYTHMOGENIC CARDIOMYOPATHY IN A LONG-DISTANCE RUNNER
Authors: Juan D Linares Velandia, Kamil Salam, Damian Valencia, Liset N. Stoletniy, Antoine Emile Sakr, Nathaniel Dittoe
Journal: Journal of the American College of Cardiology (2024)
ISOLATED PULMONARY ENDOCARDITIS IN 47 YEAR OLD MALE WITH ATYPICAL PRESENTATION AND NO PREDISPOSING FACTORS
Authors: Edmund Appiah-Kubi, Srijana Maharjan, Amit Kaura, Saleh Saleh, Richard Amoateng, Xiarepati Tieliwaerdi, Philipa Owusu-Antwi
Journal: Journal of the American College of Cardiology (2024)
COLLABORATIVE MULTIFACILITY AND MULTIMODALITY IMAGING RARE CASE CORONARY ARTERY TO LEFT VENTRICLE FISTULA
Authors: James Thompson, Anil K. Attili, Maria Velasco, Maryam Kazelka, Alexey Goloubev, Himara Koelmeyer, Patrick Hamcho-Milazzo
Journal: Journal of the American College of Cardiology (2024)
TAILORED MEDICATION MANAGEMENT: RESOLVING INAPPROPRIATE PACING IN A HYPERTROPHIC CARDIOMYOPATHY PATIENT WITH AN IMPLANTABLE CARDIOVERTER DEFIBRILLATOR
Authors: Muhammad Mohsin Zafar, Mohammad Wajih Baig, Arjun Basnet, Khurram Arshad, Tayyab Ali Waheed, Aniruddha Singh
Journal: Journal of the American College of Cardiology (2024)
TRANSIENT MID VENTRICULAR BALLOONING SYNDROME: AN ATYPICAL VARIANT OF STRESS CARDIOMYOPATHY
Authors: Andrew Takla, Kirolus Sourial, Nada Hafez, Omofolarin Babayale, Hina Ukrani, Astha Prasai, Bipul Baibhav
Journal: Journal of the American College of Cardiology (2024)
EXPLORING LEFT ATRIAL PAPILLARY FIBROELASTOMA: A UNIQUE CASE STUDY
Authors: Rand Sabanci, Manel Boumegouas, Moiz Saeed, Khalid Saeed Al-Asad, Kevin Watat, Andrew G. Kim, Adolfo Martinez, Gabriel Panama, Qi Xuan Ang, Majid Yavari, Sampath Gunda, Matthew Wilcox, Christopher Hanson
Journal: Journal of the American College of Cardiology (2024)
CONGENITALLY CORRECTED TRANSPOSITION OF THE GREAT ARTERIES WITH LEFT VENTRICULAR NONCOMPACTION OF A MORPHOLOGICAL SYSTEMIC RIGHT VENTRICLE
Authors: Christy Lougheed, Joshua Mackay, Hamza Ghannam, Nathaniel Kim, Joshua Beverly, Sanjay Polisetty, Adam Habib, Joshua Sethi, Emily Dereszkiewicz, Daniel H. Kim
Journal: Journal of the American College of Cardiology (2024)
DIAGNOSTIC DILEMMA: UNVEILING THE CRUCIAL ROLE OF TEE IN AORTIC DISSECTION CASE WITH HIGH CLINICAL SUSPICION AND NEGATIVE CT RESULTS
Authors: Arminder Singh, Jacob Giordano, Abhishek Goel, Pinang Shastri, Vibha Hayagreev, Hardik A. Fichadiya, Faisal Dadi, Ronak Bahuva, Steven Monahan, Usman Younus, Sylvester U. Ejeh, Manoj Bhandari
Journal: Journal of the American College of Cardiology (2024)
CRITICAL LEFT MAIN CORONARY ARTERY STENOSIS PRESENTING WITH NEGATIVE MYOCARDIAL PERFUSION IMAGING : A CASE OF BALANCED ISCHEMIA
Authors: Walter Y. Agyeman, Sammudeen Ibrahim, Saint-Martin Allihien, Patrick O. Berchie, Kikelomo Olaosebikan, Basilio Addo
Journal: Journal of the American College of Cardiology (2024)
A RARE CASE OF FABRY DISEASE (FD) IN A FEMALE WITH HYPERTROPHIC CARDIOMYOPATHY (HCM)
Authors: Asmaa Ahmed, Nada Hafez, Lyudmila Kuchma, Andrew Takla, Bipul Baibhav, Mohamed Salah Mohamed, Omofolarin Babayale
Journal: Journal of the American College of Cardiology (2024)