tbuckley/cabot-search huggingface dataset:
WED-291 Long risk of decompensation and HCC in patients with HDV- related compensated cirrhosis treated with Bulevirtide monotherapy for up to 144 weeks: the retrospective multicenter european study (Save-D)
Authors: Elisabetta Degasperi, Maria Paola Anolli, Liana Gheorghe, Mirela Chitul, Christoph Schramm, Hartmut Schmidt, Mathias Jachs, Thomas Reiberger, Juliette Foucher, Sophie Metivier, Maria Buti, Adriana Palom, Giampiero D’Offizi, Francesco de Maria, Caroline Zöllner, Frank Tacke, Christopher Dietz-Fricke, Heiner Wedemeyer, Margarita Papatheodoridi, George Papatheodoridis, Ivana Carey, Kosh Agarwal, Florian van Bömmel, Maurizia Brunetto, Mariana Cardoso, Elena Rosselli Del Turco, Alessia Ciancio, Sabela Lens, Alvaro Giráldez-Gallego, Fabien Zoulim, Soo Aleman, Nasser Semmo, Alessandra Mangia, Marie-Noëlle Hilleret, Uta Merle, Teresa Santantonio, Nicola Coppola, Adriano Pellicelli, Bruno Roche, Xavier Causse, Louis Dalteroche, Jérôme Dumortier, Nathalie Ganne-Carrié, Frederic Heluwaert, Isabelle Ollivier-Hourmand, Dominique Roulot, Mauro Viganò, Alessandro Loglio, Alessandro Federico, Francesca Pileri, Monia Maracci, Matteo Tonnini, Jean-Pierre Arpurt, Karl Barange, Eric Billaud, Stanislas Pol, Anne Gervais, Anne Minello Franza, Isabelle Rosa, Massimo Puoti, Pietro Lampertico
Journal: Journal of Hepatology (2025)
THU-341 Implementation of a clinical global impression severity scale for primary biliary cirrhosis: results of a hepatologist focussed training programme
Authors: Nasir Hussain, Sarah Barnum, Mo Christie, Robert Mitchell-Thain, James Neuberger, Andreas E. Kremer, Magnus Doverskog, Palak Trivedi, Judith Jaeger, David E. Jones
Journal: Journal of Hepatology (2025)
FRI-134 Impact of radiation dose on treatment response and survival outcomes in solitary hepatocellular carcinoma treated withY90 selective internal radiation therapy: a retrospective single-center study
Authors: Kaina Chen, Lu Yang, Aaron Kian Ti Tong, David Chee Eng Ng, Kelvin Siu Hoong Loke, Sue Ping Thang, Apoorva Gogna, Richard Hoau Gong Lo, Karaddi Venkatanarasimha Nanda Kumar, Fiona Ni Ni Moe, Siou Sze Chua, Cheryl Min En Chua, Jade Shu Qi Goh, Evelyn Chiew, Pierce Chow
Journal: Journal of Hepatology (2025)
Targeting CD38 with Daratumumab for Platelet Transfusion Refractoriness in Aplastic Anemia
Authors: Zhen Gao, Hong Pan, Lele Zhang, Weiwang Li, Ruonan Li, Jingyu Zhao, Yuechen Luo, Yu Lian, Xiao Yu, Zhexiang Kuang, Neng Nie, Jianping Li, Jinbo Huang, Xin Zhao, Yuan Li, Liwei Fang, Meili Ge, Yizhou Zheng, Jun Shi
Journal: Blood (2025)
SAT-161 Prevalence and prognosis of cirrhotic cardiomyopathy in hospitalized patients with decompensated cirrhosis
Authors: Cristina Solé, Judith Cortada, Francesca Castaldo, Jordi Sánchez, José Ferrusquía-Acosta, Meritxell Casas, Mireia Miquel, Mario Sutil, Laura Guillamón, Eva Guillaumet, Núria Casanovas, Andrés Ribas, Antonio Martínez, Mercedes Vergara
Journal: Journal of Hepatology (2025)
THU-007 Real-world experience using serial transient elastography by FibroScan in a community outreach service for the earlier detection of liver disease
Authors: Ann Archer, Zin Oo, Alexandra Kondratiuk, Robbie Adamson, Sally Tilden, Rosemary King’ori, James Hawken, Fiona Gordon, Kushala Abeysekera
Journal: Journal of Hepatology (2025)
LBP-027 Elafibranor improves fatigue versus placebo in patients with primary biliary cholangitis, with limited correlation with pruritus: analyses from the phase III ELATIVE® trial
Authors: David E. Jones, Marco Carbone, Andreas E. Kremer, Cynthia Levy, Marlyn J. Mayo, Jörn M. Schattenberg, Nuno Antunes, Darren Asquith, Hugo Gomes da Silva, Mickael Lothgren, Marwan Sleiman, Nathan Touati, Mark Swain
Journal: Journal of Hepatology (2025)
WED-341-YI Kinetics of copper uptake in liver cells using the novel ligand tracer method
Authors: Karina Rewitz, Mikkel Holm Vendelbo, Mie Ringgaard Dollerup, Mia Blum, Sidsel Støy, Steffen Sinning, Hendrik Vilstrup, Peter Ott, Thomas Damgaard Sandahl
Journal: Journal of Hepatology (2025)
WED-047 A single center experience from India on associations of fungal microbiota (mycobiome) in cirrhosis - orally-predominant fungal dysbiosis in the gut and immune-escaping Candida species drive outcomes in hospitalized patients
Authors: Cyriac Philips, Arif Theruvath, Ansu Alex, Jitendra Keshri, Gunisha Pascricha, Jayasankar Madhusoodhanan, Subash Nagarajan, Yogeshwar Krishnan, Rajadurai Perumal, Philip Augustine
Journal: Journal of Hepatology (2025)
THU-164 Mitochondrial transfer from mesenchymal stem cells to hematopoietic stem cells mitigates bone marrow failure and promotes liver regeneration in pre-clinical model of cirrhosis
Authors: Manisha Bhardwaj, Deepanshu Maheshwari, Nidhi Nautiyal, Sandeep Kumar, Sunidhi Diwakar, Nikita Sharma, Anupam Kumar, Shiv Kumar Sarin, Anupama Kumari
Journal: Journal of Hepatology (2025)
THU-350-YI Impact of non-classical phenotypes of primary biliary cholangitis on treatment response and long-term prognosis. Results from the ColHai registry
Authors: Pinelopi Arvaniti, Helena Hernández Evole, Magdalena Salcedo, Ignasi Olivas, Nerea Quintans, Cristina Montón, Margarita Sala Llinás, Mar Riveiro Barciela, Ares Villagrasa, Agustin Castiella, Álvaro Díaz-González, Indhira Perez Medrano, Carmen Álvarez-Navascués, Ana Arencibia Almeida, Emily Larrea, Rosa M Morillas, Javier Ampuero Herrojo, Sara Lorente, Isabel Conde, Alejandra Villamil, Montserrat García-Retortillo, Pilar Griño, Hector Calduch, Beatriz Mateos Muñoz, Judith Gomez-Camarero, Miren Garcia Cortes, Diana Horta, María Rios Peset, Ismael El Hajra Martínez, Raquel Lomas, Natalia García Gimeno, Francisca Cuenca Alarcon, Silvia Goñi Esarte, Isabel Aured, Gabriel Mezzano, Inmaculada Castello, Berta Lapeña, Carmen Vila, Raquel Ríos León, Vanesa Bernal, Eva Fernandez Bonilla, Marlene Padilla-Lopez, Pere Borràs, María Del Barrio, Javier Martínez González, Natalia Sobenko, Eva María Zapata, Sheila González, Maria Valenzuela, Lissa Franco, Marina Berenguer, Antonio Olveira, Alvaro Giménez Manzorro, Sergio Rodriguez-Tajes, Maria Carlota Londoño
Journal: Journal of Hepatology (2025)
LBO-004 Final results of MYR301: a randomised phase 3 study evaluating the efficacy and safety of up to 144 weeks of bulevirtide monotherapy for chronic hepatitis delta and 96 weeks of posttreatment follow-up
Authors: Heiner Wedemeyer, Soo Aleman, Antje Blank, Pietro Andreone, Pavel Bogomolov, Vladimir Chulanov, Nina Mamonova, Natalia Geyvandova, Viacheslav Morozov, Olga Sagalova, Tatiana Stepanova, Annemarie Berger, Sandra Ciesek, Amos Lichtman, Dmitry Manuilov, Renee-Claude Mercier, Sarah Arterburn, Florence Christian-Cox, Steve Tseng, Anu Osinusi, Julian Schulze zur Wiesch, Markus Cornberg, Stefan Zeuzem, Maurizia Brunetto, Pietro Lampertico
Journal: Journal of Hepatology (2025)
SAT-401 Liver disease progression in patients with alpha-1 antitrypsin deficiency and a Pi*ZZ genotype: a retrospective natural history study
Authors: Virginia C. Clark, May Hagiwara, Jeanine M. D’Armiento, Monica P. Goldklang, Jeffrey H. Teckman, Alice Turner, Gerald Lebovic, Flavia Soares Peres, Cláudia Ribeiro, Doneal Thomas, Chitra Karki, Ed G. Marins, Suna Park, Kaili Ren, Anne E. Wyman, Pavel Strnad
Journal: Journal of Hepatology (2025)
SAT-170-YI Variables associated with postoperative mortality in advanced chronic liver disease patients undergoing urgent or elective surgery. a multicentre spanish cohort
Authors: Lidia Canillas, Natalia Jimenez-Esquivel, Alberto Amador, Anna Brujats, Jordi Sánchez, Amalia Pelegrina, Carlos Pardo, Sergi Homdedeu Montaña, Montse Camps, Carla de Sárraga, Adrián Vizoso, Juan Álvarez, Fernando Burdio, Enric Reverter, Jose A. Carrión
Journal: Journal of Hepatology (2025)
THU-454 Coagulation imbalance is associated with hepatic and vascular complications in patients with MASLD and diabetes: key role of factor VIII
Authors: Rosa Lombardi, Roberta Forlano, Gabriele Maffi, Annalisa Cespiati, Felice Cinque, Daniela Bignamini, Paola Dongiovanni, Paolo Francione, Marica Meroni, Giordano Sigon, Jian Huang, Pinelopi Manousou, Flora Peyvandi, Armando Tripodi, Anna Ludovica Fracanzani
Journal: Journal of Hepatology (2025)
GS-001 Diagnostic performance of imaging and serum based MASLD biomarkers: robust validation in the prospective LITMUS imaging study
Authors: Michael Pavlides, Yasaman Vali, Ferenc Mozes, Kristy Wonders, Salma Akthar, Guruprasad Aithal, Rocío Aller, Michael Allison, Johanna Arola, Rajarshi Banerjee, Annalisa Berzigotti, Jerome Boursier, Clifford Brass, Elisabetta Bugianesi, Jeremy Cobbold, Harvey O. Coxson, Susan Davies, Ann Driessen, Kevin Duffin, Richard L. Ehman, Mattias Ekstedt, Céline Fournier-Poizat, Annette Gouw, Paul Hockings, Prodromos Hytiroglou, Michael J. Kalutkiewicz, Morten Karsdal, Carolin Lackner, Diana Julie Leeming, Jeremy Magnanensi, Miljen Martic, Stefan Neubauer, Valérie Paradis, Kay Pepin, Juan Manuel Pericàs, Salvatore Petta, Vlad Ratziu, Manuel Romero-Gómez, Jörn M. Schattenberg, Moritz Schneider, Detlef Schuppan, Elizabeth Shumbayawonda, Beate Straub, Joanne Verheij, Mette Kjaer, Dina Tiniakos, Maria Manuela Tonini, Richard Torstenson, Hannele Yki-Järvinen, Theresa Tuthill, Carla Yunis, David Wenn, Patrick Bossuyt, Quentin Anstee
Journal: Journal of Hepatology (2025)
SAT-320 Combination therapy of entecavir, peginterferon alpha and granulocyte-macrophage colony stimulating factor enhanced HBsAg loss and HBsAb response
Authors: Di Wu, Da Huang, Shifang Peng, Yongping Chen, Fengchun Yang, Xiaoyun Zhang, Lei Fu, Lanman Xu, Jiaji Jiang, Qi Zheng, Xin-Yue Chen, Yali Liu, Xiaoguang Dou, Ke Ma, Dong Xi, Peng Wang, Li Sun, Ruoyi He, Yuchen Tian, Ping Yin, Weiming Yan, Meifang Han, Qin Ning
Journal: Journal of Hepatology (2025)
SAT-286 Risk of hepatocellular carcinoma and other liver-related events in chronic hepatitis B patients with or without hepatitis D virus co- infection
Authors: Lesley Patmore, Michelle Spaan, Kosh Agarwal, Özgür Koc, Hans Blokzijl, Samantha Brouwer, Hanneke van Soest, Astrid van Hulzen, Harry L.A. Janssen, Annemiek van der Eijk, Jolanda Lammers, Louis Jansen, Mark Claassen, Robert A. de Man, R. Bart Takkenberg, Remco van Dijk, Dirk Posthouwer, Jurriën Reijnders, Ivana Carey, Milan J. Sonneveld
Journal: Journal of Hepatology (2025)
SAT-065-YI Engineered extracellular vesicles derived from mesenchymal stem cell carrying insulin-like growth factor I to promote liver regeneration after partial hepatectomy
Authors: Mailín Casadei, María José Cantero, Bárbara Bueloni, Fatima Huaman, Lucia Lameroli Mauriz, Natalia Pacienza, Catalina Atorrasagasti, Juan Bayo Fina, Guillermo Mazzolini, Esteban Fiore
Journal: Journal of Hepatology (2025)
WED-466-YI Serum biomolecules improve liver enzyme-based prediction scores of significant liver fibrosis and fibrotic metabolic dysfunction-associated steatohepatitis
Authors: Nateneal Beyene, Lotte Schoenmakers, Wilhelmus J Kwanten, Eveline Dirinck, An Verrijken, Jolien Derdeyn, Toon Steinhauser, Thomas Vanwolleghem, Ann Driessen, Christophe de Block, Sven Francque, Luisa Vonghia
Journal: Journal of Hepatology (2025)
Comparison of diagnostic accuracy and utility of non-invasive tests for clinically significant liver disease in a general population with metabolic dysfunction
Authors: Laurens A. van Kleef, Jesse Pustjens, Jörn M. Schattenberg, Adriaan G. Holleboom, Manuel Castro Cabezas, Maarten E. Tushuizen, Robert J. de Knegt, M. Arfan Ikram, Harry L.A. Janssen, Sven M. Francque, Willem Pieter Brouwer
Journal: Hepatology (2025)

Background: Screening for liver disease in the general population requires accurate non-invasive tests (NITs). A head-to-head comparison of NITs for early detection of clinically relevant liver disease among the target population for screening is lacking. Methods: Among meta-cohort (Rotterdam Study and NHANES) with metabolic dysfunction aged 18-80 years, 10 NITs were investigated. The diagnostic accuracy for clinically relevant conditions (increased liver stiffness measurement [LSM], at-risk MASH, advanced fibrosis or cirrhosis) was assessed. Subgroup analysis included stratification by age group and diabetes/obesity status. Results: We analysed 11,404 participants. MAF-5 obtained the highest AUC for increased LSM (≥8kPa:0.80; ≥12kPa:0.87) and advanced fibrosis (AUC:0.90). FNI and MAF-5 performed best for detecting MASH (AUC:0.93 and AUC:0.92, P =ns) and SAFE for cirrhosis (AUC:0.92). To obtain 80% sensitivity for LSM ≥8kPa, the corresponding MAF-5 cut-off resulted in fewer referrals (42%) compared to FIB-4 (77%) and higher specificity (62% vs. 24%); MAF-5 was also superior for detection of LSM ≥12kPa and advanced fibrosis. Age-dependent scores yielded lower sensitivity amongst younger individuals e.g., by referring 20% of the population with highest NIT-scores, the FIB-4, SAFE, NFS, FORNS and HFS yielded &lt;10% sensitivity for LSM ≥8kPa amongst individuals aged 18-35y while FNI and MAF-5 obtained 40% and 71%. Conclusions: Of the 10 investigated NITs, MAF-5 discriminated best between all conditions except cirrhosis, for which SAFE yielded the highest accuracy. The performance of FIB-4 was poor, implying that referral pathways for significant liver disease in low-prevalence populations can be improved when more accurate NITs such as MAF-5 are employed.
THU-212 Overweight, but not alcohol is associated with increased risk for advanced liver disease in patients with chronic hepatitis C infection- results from the german hepatitis C-registry (DHC-R)
Authors: Katharina Luise Hupa-Breier, Peter Buggisch, Hartwig Klinker, Stefan Mauss, Renate Heyne, Karl-Georg Simon, Thomas Berg, Andreas Geier, Heiner Wedemeyer, Monika Rau
Journal: Journal of Hepatology (2025)
WED-241 Changes in spleen stiffness as assessed via vibration-controlled transient elastography at 100 Hz reflect acute hepatic venous pressure gradient response to i.v. propranolol: a european multicenter study
Authors: Paul Thöne, Dario Saltini, Joana Calvão, Lorenz Balcar, Tomas Guasconi, Georg Semmler, Albert Friedrich Stättermayer, Michael Trauner, Thomas Reiberger, José Presa, Filippo Schepis, Mattias Mandorfer, Mathias Jachs
Journal: Journal of Hepatology (2025)
WED-450-YI The use of controlled attenuationparameter for the assessment of treatment response in patients with metabolic dysfunctionassociated steatotic liver disease undergoing a lifestyle intervention program
Authors: Lorenza Vaira, Angelo Armandi, Chiara Rosso, Gian Paolo Caviglia, Martina Marano, Fabrizio Amato, Kamela Gjini, Marta Guariglia, Eleonora Dileo, Ilaria Goitre, Davide Giuseppe Ribaldone, Simona Bo, Elisabetta Bugianesi
Journal: Journal of Hepatology (2025)
WED-081-YI Role of alcohol-associated gut microbiota in driving liver fibrosis via tgfbr1 kinase alterations in alcohol associated liver disease
Authors: Manisha Yadav, Abhishak Gupta, Neha Sharma, Vasundhra Bindal, Sanju Yadav, Rimsha Rimsha, Gaurav Tripathi, Nupur Sharma, Sushmita Pandey, Babu Mathew, Shiv Kumar Sarin, Jaswinder Maras
Journal: Journal of Hepatology (2025)
LBP-014 HBsAg loss and seroconversion after 16-week or 24-week AHB-137 treatment in HBeAg-negative chronic hepatitis B participants on NA therapy: results from an ongoing multicenter, randomized phase IIb study
Authors: Yanhang Gao, Xieer Liang, Youwen Tan, Haibing Gao, Dachuan Cai, Jidong Jia, Xinrui Wang, Zhihong Liu, Xingbei Zhou, Huaxi Ma, Shan Zhong, Hong Ma, Di Zhao, Chen Yang, Hao Wang, Miao Wang, Cheng Yong Yang, Guofeng Cheng, Jinlin Hou, Junqi Niu
Journal: Journal of Hepatology (2025)
Menin inhibition with revumenib for NPM1-mutated relapsed or refractory acute myeloid leukemia: the AUGMENT-101 study
Authors: Martha L. Arellano, Michael J. Thirman, John F. DiPersio, Mael Heiblig, Eytan M. Stein, Andre C. Schuh, Andrius Zucenka, Stéphane De Botton, Carolyn S. Grove, Gabriel N. Mannis, Cristina Papayannidis, Alexander E. Perl, Ghayas C. Issa, Ibrahim Aldoss, Ashish Bajel, David S. Dickens, Michael W.M. Kühn, Ioannis Mantzaris, Emmanuel Raffoux, Elie Traer, irina Amitai, Hartmut Döhner, Corinna Greco, Tibor J. Kovacsovics, Christine M. McMahon, Pau Montesinos, Arnaud Pigneux, Paul J. Shami, Richard M. Stone, Ofir Wolach, John G. Harpel, Yakov Chudnovsky, Li Yu, Rebecca G. Bagley, Angela R. Smith, James S. Blachly
Journal: Blood (2025)

The prognosis for relapsed or refractory (R/R) nucleophosmin 1-mutated (NPM1m) acute myeloid leukemia (AML) is poor and represents an urgent unmet medical need. Revumenib, a potent, selective menin inhibitor, was recently approved for the treatment of R/R acute leukemia with a KMT2A translocation in patients aged ≥1 year based on results from the phase 1/2 AUGMENT-101 study. Here we present results from patients with R/R NPM1m AML enrolled in the phase 2 portion of AUGMENT-101. Enrolled patients received revumenib with or without a strong CYP3A4 inhibitor every 12 hours in 28-day cycles. Primary endpoints were rate of complete remission (CR) or CR with partial hematologic recovery (CRh; CR+CRh), and safety and tolerability. Secondary endpoints included overall response rate (ORR) and duration of response. As of September 18, 2024, 84 patients received ≥1 dose of revumenib. Median age was 63 years; 1 patient was aged &amp;lt;18 years. The protocol-defined efficacy-evaluable population for the primary analysis included 64 adult patients (≥3 prior lines of therapy, 35.9%; prior venetoclax, 75.0%). The CR+CRh rate was 23.4% (1-sided P=.0014); the ORR was 46.9%. Median duration of CR+CRh was 4.7 months. Five of 30 responders (16.7%) proceeded to hematopoietic stem cell transplant (HSCT); 3 resumed revumenib after HSCT. Treatment-related adverse events led to treatment discontinuation in 4 patients (4.8%). Revumenib demonstrated clinically meaningful responses in this heavily pretreated, older population with NPM1m AML, including remissions that enabled HSCT. The safety profile of revumenib was consistent with previously reported results. This trial was registered at www.clinicaltrials.gov as NCT04065399.
WED-264 Glecaprevir/pibrentasvir in chronic HCV: an integrated analysis of patients on concomitant opioids, antipsychotics and cardiovascular medications
Authors: Curtis Cooper, Shweta Raina, Lisa W. Johnson, Jordan J. Feld, Ashley Brown, Anthony Martinez, Brian Conway, Stuart C Gordon, Tarik Asselah, Liz Uribe, Moming Li, Alexandru Iacob, John Marcinak, Dimitri Semizarov, Stanislas Pol
Journal: Journal of Hepatology (2025)
SAT-518 The recovery failure of fecal microbiota diversity in patients after liver transplant is associated with a complicated postoperative course
Authors: Anna Lautz, Maike Rebecca Pollmanns, Nicole Treichel, Sophia Schlaak, Florian Vondran, Ulf Peter Neumann, Alexander Koch, Thomas Clavel, Tony Bruns, Christian Trautwein, Theresa Hildegard Wirtz
Journal: Journal of Hepatology (2025)
FRI-221 APASL ACLF research consortium (AARC) liver failure score and first week(transplant window) defines the limits of medical management and time frame for liver transplant in acute on chronic liver failure patients
Authors: Ashok Choudhury, Guan-Huei Lee, Sudhir Verma, Rakhi Maiwall, Vinod Arora, Mohamed Rela, Dinesh Jothimani, Mamun Al-Mahtab, Harshad Devarbhavi, CE Eapen, Ashish Goel, Cesar Yaghi, Qin Ning, Tao Chen, Jidong Jia, Zhongping Duan, Saeed Sadiq Hamid, Amna Subhan, Wasim Jafri, Akash Shukla, Soek-Siam Tan, Jinhua Hu, Ajit Sood, Omesh Goyal, Vandana Midha, Manoj Sahoo, Sombat Treeprasertsuk, Kessarin Thanapirom, Ameet Mandot, Samir Shah, Ravikiran Maghade, Laurentius A. Lesmana, Hasmik Ghazinyan, Mohan V.G. Prasad, A. Kadir Dokmeci, Jose Sollano, Zaigham Abbas, Ananta Shrestha, George Lau, Diana Payawal, Ajay Kumar Duseja, Gamal Shiha, Sunil Taneja, Nipun Verma, Nagaraja Rao Padaki, Anand Kulkarni, Mithun Sharma, Fazal Karim, Radha Krishan Dhiman, Ajay Mishra, Shahinul Alam, Osamu Yokosuka, Dr. Debashis Chowdhury, Chandan Kedarisetty, Dr. Sanjiv Saigal, Anil Arora, Ashish Kumar, Ghulam Nabi Yattoo, Abraham Koshy, Ajay Kumar, Mohammed Elbasiony, Sudhir Maharshi, V.M. Dayal, Ashish Kumar Jha, Kemal Fariz Kalista, Pravin Rathi, Rino Gani, Man-Fung Yuen, Virendra Singh, Janaka De Silva H., Gupse Adali, Krishnadas Devadas, Chetan Kalal, Mahesh Goenka, Akash Roy, Narendra S. Choudhary, Neeraj Saraf, P. Javed, Pathik Parikh, Dr. Joy Varghese, Hemamala Venugopal Saithanyamurthi, Lubna Kamani, Prabir Maji, Sanatan Behera, Ajay Kumar, Sanjeev Sachdeva, Sunil Dadhich, Charles Panackel, Ruveena Bhavani, Shaojie Xin, Saurabh Mukewar, Chien-Hao Huang, Sargsyan Violeta, Ayaskant Singh, Shiv Kumar Sarin
Journal: Journal of Hepatology (2025)
WED-516 Bile acids drive fibroblast activation, fibrogenesis, interstitial matrix fibrosis and outcomes in PSC
Authors: Morten Karsdal, Tom Hemming Karlsen, Mette Vesterhus, Andressa de Zawadzki, Lei Ling, Cory Kostrub, Pamela Vig, Diana Julie Leeming
Journal: Journal of Hepatology (2025)
THU-142-YI Early detection of hepatic encephalopathy using wearable sensors: preliminary data
Authors: Clelia Asero, Maria Stella Franzè, Giorgio Lo Giudice, Dario Milone, Cristiano de Marchis, Roberto Filomia, Gaia Caccamo, Concetta Pitrone, Carlo Saitta, Irene Cacciola
Journal: Journal of Hepatology (2025)
ANKRD26-related Thrombocytopenia 2 with a Baseline Increase in Blasts: Implications for Clinical Surveillance
Authors: Lara Wahlster, Lucy A Godley, Jason X Cheng, Michael W Drazer, Christopher R. Reilly, Geraldine S Pinkus, Jared H Rowe, Nina Weichert-Leahey, Robert Grant Rowe, Lev Gorfinkel, Karyn Jean Brundige, Franziska Wachter, Luana Miria Messa, Alan D Michelson, Alan B. Cantor, Akiko Shimamura, Jacob R Bledsoe
Journal: Blood (2025)
SAT-036 Physician perspectives on hepatitis C treatment for women of childbearing age and during pregnancy: results from a global multispecialty survey
Authors: Tatyana Kushner, Maria Buti, George Papatheodoridis, Mohamed El-Kassas, Yusuf Yilmaz, Hirokazu TakahashI, Yuichiro Eguchi, Stuart Roberts, Wah-Kheong Chan, Ming-Lung Yu, Ponsiano Ocama, Saira Khaderi, Manida Wungjiranirun, Ira Jacobson, Stuart C. Gordon, Aina Nicolàs Olivé, John Ward, Neil Gupta, Lindsey Hiebert, Sheila Reynoso, Andrei Racila, Linda Henry, Maria Stepanova, Zobair Younossi
Journal: Journal of Hepatology (2025)
FRI-229 Interferon-α induces robust neutralizing anti-HBs production by restoring the HBsAg-specific B cell immune response in nucleos(t) ide analogues experienced chronic hepatitis B patients
Authors: Zhize Yuan, Da Huang, Di Wu, Yuying Chen, Jiang Chang, Yizhi Wu, Ran Zhao, Weiming Yan, Qin Ning
Journal: Journal of Hepatology (2025)
WED-384 Non-invasive identification of MASLD patients eligible for resmetirom treatment – data from a multicenter biopsy-proven MASLD cohort
Authors: Katharina John, Martin Franck, Monika Rau, Andreas Geier, Jan-Peter Sowa, Jörn M. Schattenberg, Münevver Demir, Heiner Wedemeyer, Klaus Schulze-Osthoff, Heike Bantel
Journal: Journal of Hepatology (2025)
OS-087 Amongst autoimmune liver diseases, primary sclerosing cholangitis demonstrates distinct methylation profiles on circulating DNA
Authors: Soumita Ghosh, Cristina Baciu, Elisa Pasini, Madeline Cameron, Shani Nagler, Aisha Alawi, Aliya Gulamhusein, Gideon M. Hirschfield, Mamatha Bhat
Journal: Journal of Hepatology (2025)
THU-489 Disruption of receptor-interacting protein kinase 1 post-translational modifications in alcohol-associated liver disease
Authors: Uttam Ojha, Megan McMullen, Vai Pathak, Adam Kim, Daniel Rotroff, Srinivasan Dasarathy, Jaividhya Dasarathy, David Streem, Nicole Welch, Laura Nagy
Journal: Journal of Hepatology (2025)
THU-156-YI An antimicrobial peptide, melittin attenuates gut urease activity and ammonia production in experimental model of cirrhosis
Authors: Deepika Jakhar, Pinky Juneja, Aarti Sharma, Bhaskar Sharma, Dinesh Mani Tripathi, Shiv Kumar Sarin, Savneet Kaur
Journal: Journal of Hepatology (2025)
THU-187 Efficacy of the apoptosis-signal-regulating kinase 1 (ASK1) inhibitor SRT-015 in in vivo and in vitro pathogen-associated molecular patterns (PAMPs)-induced disease models
Authors: Vanessa Legry, Manon Clarisse, Simon Debaecker, Nicolas Stankovic Valentin, Philippe Poulain, Dean Hum, Bart Staels, Joan Clària, Sakina Sayah Jeanne
Journal: Journal of Hepatology (2025)