tbuckley/cabot-search huggingface dataset:
A multicenter approach for the development of an artificial intelligence algorithm for the evaluation of pancreatic cystic lesions during endoscopic ultrasound
Authors: B. Agudo, M. Mascarenhas, M. González-Haba Ruiz, T. Ribeiro, J. Ferreira, J. P. Afonso, M. Francisco, M. Martins, C. Pedro, F. Vilas Boas, M. Guilherme
Journal: Endoscopy (2024)

Aims Pancreatic cystic lesions (PCLs) are increasingly prevalent findings due to the improvement in abdominal imaging techniques. Although most of these lesions are benign and do not require specific follow-up, their etiology is varied, and some are associated with an increased risk of malignancy. The risk of malignancy is almost exclusive of mucinous PCLs (M-PCLs). The distinction between M-PCL and non-mucinous PCLs (NM-PCLs) is essential for the management of these patients, and endoscopic ultrasound (EUS) plays as key role for the morphological, biochemical and cytological evaluation of these lesions, despite these parameters show a suboptimal performance. The application of artificial intelligence (AI) to EUS has provided promising results, including for the evaluation of PCLs. Nevertheless, to this date, existing evidence is limited to small unicentric studies. This study provides a multicentric approach with the aim of developing a convolutional neural network (CNN) for the automatic detection and differentiation of M-PCLs and NM-PCLs.
Elderly vs. young patients : clinical, endoscopic and prognostic particularities in case of upper gastrointestinal hemorrhage : prospective study
Authors: I. Mouslim, A. Benhamdane, R. Chaibi, T. Addajou, S. Mrabti, R. Berraida, I. Elkoti, R. Fedoua, S. Hassan
Journal: Endoscopy (2024)

Aims Upper GI bleeding (UGI) is the most common reason for emergency hospitalization in hepato-gastroenterology. However, there are not enough studies comparing clinical and endoscopic features between young and elderly patients with upper GI bleeding.
International validation of a PEACE scale assessing cleanliness during esophagogastroduodenoscopy to improve the quality of inspection during endoscopy
Authors: M. Romańczyk, M. Desai, M. F. Kaminski, S. Abe, A. Alkandari, T. Beyna, R. Bisschops, K. Budzyń, M. Bugdol, S. C. Grover, P. Gyawali, H. Inoue, P. G. Iyer, H. Messmann, K. Ragunath, Y. Saito, S. Srinivasan, C. Teshima, R. Yadlapati, C. Hassan, P. Sharma
Journal: Endoscopy (2024)

Aims Upper gastrointestinal (UGI) endoscopy quality depends on the capability to detect mucosal pathologies. Proper visibility is necessary to identify lesions and subtle mucosal abnormalities. The PEACE scale (Polprep: Effective Assessment of Cleanliness in Esophagogastroduodenoscopy) was recently created to assess UGI cleanliness. Cleanliness assessed using the PEACE scoring system was directly related to detection of clinically significant pathologies 1. The aim of this study was to validate the concordance of the PEACE scoring system globally.
A novel post-colonoscopy thromboembolic risk predictor (PTRP) in patients on antithrombotic agents: a validation study
Authors: K.L. T. Lui, J. Chen, C. Guo, K. S. Cheung, K.S. H. Liu, W. K. Leung
Journal: Endoscopy (2024)

Aims Patients receiving anti-thrombotic agents are at a heightened risk of both bleeding and thromboembolic (TE) events during colonoscopy. Identifying high-risk patients is crucial to determine the need for more robust prophylactic measures to mitigate the risk of bleeding during colonoscopy and enable a timely resumption of antithrombotic agents. This study explores the efficacy of novel artificial intelligence models in predicting the risk of post-colonoscopy TE events.
A Pre-Colonoscopy Personalized Digital Platform Markedly Reduces Ambulatory Colonoscopy ‘No-Show’ rates
Authors: E. Ritter, M. Leshno, M. Shnell, O. Shibolet, L. Deutsch
Journal: Endoscopy (2024)

Aims Colonoscopy is a well-established screening tool for detection of colorectal lesions. Colonoscopy waiting-lists can last for months, however, the rates of unperformed procedures due to patients' absence ('no-show') are 8-15% globally. The aim of this study was to evaluate whether a personalized digital platform would reduce 'no-show' rates for ambulatory colonoscopies.
Large Language Model Chat GPT-4 Can Outperform Clinicians in Endoscopy Triage
Authors: J. R. Campion, J. Cudmore, E. Keating, H. Kerr, S. Stewart, J. Leyden, B. Kelleher, J. Mulsow, C. Lahiff, G. Bennett
Journal: Endoscopy (2024)

Aims We sought to compare adherence to current national and international guidelines on triage of new patient referrals and surveillance endoscopy procedures between a commercially-available general large language model (LLM) and clinical staff working in an academic department of gastroenterology.
Bleeding severity: defining and evaluating its role on mortality risk. A prospective multicentre cohort study
Authors: C. Marmo, C. Bucci, R. Marmo, M. Soncini
Journal: Endoscopy (2024)

Aims Severe gastrointestinal bleeding is recognised as a risk factor for mortality but a proper definition or objective criteria to score its magnitude is lacking. Bleeding severity impacts the pre-endoscopic clinical management decision process and the timing of the endoscopy. Our aim was I) to identify independent factors contributing to the bleeding severity II) to grade its severity and III) to verify the impact of bleeding severity on mortality risk.
Sequential vs Simultaneous Intervention in Multiple Infected Pancreatic Necrotic Collections in Patients with Acute Necrotizing Pancreatitis: A Randomized Trial
Authors: V. S. Bikkina, J. Shah, P. Gupta, H. Bhujade, S. Y. Raj, S. Ancil, V. Jearth, A. K. Singh, H. S. Mandavdhare, V. Sharma, S. Rana, U. Dutta
Journal: Endoscopy (2024)

Aims Minimally invasive step-up approach is the recommended modality of treatment in patients with infected pancreatic necrosis (IPN). Majority of patients with pancreatic collections are having a single IPN, however, some patients with necrotizing pancreatitis have multiple IPNs. In such scenario, whether drainage of all collections simultaneously has better clinical outcome compared to draining collections sequentially as per clinical response has not been explored earlier. Theoretically, it can fasten the clinical improvement with better outcome, albeit with higher number of interventions. We performed a single center, open label, randomized trial to compare sequential drainage vs simultaneous drainage of multiple IPNs in patients with acute necrotizing pancreatitis (ANP). [1] [2]
BD-IPMN surveillance: a real-life experience from an Italian level III center
Authors: M. Terrin, V. Poletti, M. Mercurio, F. Minini, M. Spertino, D. P. Cataldo, C. Bonifacio, M. Spadaccini, M. Colombo, P. Spaggiari, M. Sollai, M. Andreozzi, R. E. Rossi, S. Bozzarelli, A. Fugazza, A. Repici, A. Zerbi, S. Carrara
Journal: Endoscopy (2024)

Aims Risk of branch duct intraductal papillary-mucinous neoplasms (BD-IPMNs) to harbor malignancy is not clearly understood, especially in relation to unfavorable evolutions after long periods of stability. Therefore, follow up (FU) is often continued indefinitely, resulting in significant healthcare costs. However, a recent multicenter study showed that the risk of developing cancer in presumed BD-IPMNs without worrisome features (WF) or high-risk stigmata (HRS) after 5 years of stability is equivalent to an age-matched population based on cyst size. The authors proposed to discontinue the FU after 5 years of stability in patients 75 years or older with cysts<30 mm and in patients 65 years or older with cysts≤15mm. Aim of this study is to evaluate the risk of malignant transformation, surgery and death related to BD-IPMN without WF/HRS at diagnosis, in a real-life cohort of patients under surveillance, particularly after 5 years of FU and among patients that potentially fulfilled criteria for discontinuing surveillance.
Prospective validation of the Barcelona scale for the assessment of cleanliness in upper gastrointestinal endoscopy
Authors: C. El Maimouni, H. Cordova, E. Barreiro, E. Castillo-Regalado, P. G. Delgado-Guillena, M. P. Diez Redondo, M. Galdín, L. Hernández, J. Jimenez, J. Tejedor, M. H. Nuñez Rodriguez, A. Seoane, A. García-Rodríguez, O. Ortiz, L. Rivero Sánchez, R. S. Carballal, I. Luzko Scheid, J. Llach, L. Moreira Ruiz, G. Fernandez-Esparrach
Journal: Endoscopy (2024)

Aims Proper visibility of the mucosa is required in order to detect clinically significant lesions (CSL) in the upper gastrointestinal (GI) tract. However, there are few scales with prospective validation for the assessment of the upper GI mucosal cleanliness during upper GI endoscopy.
Real-time AI-powered EUS imaging analysis software for detection and segmentation of cystic versus solid pancreatic lesions
Authors: J. Y. Bang, A. Saftoiu, A. L. Udriștoiu, L. Gruionu, E. C. Gheorghe, P. Willems, G. Gruionu, S. Varadarajulu
Journal: Endoscopy (2024)

Aims Detection and differentiation of cystic versus solid pancreatic lesions prior to performance of EUS-guided fine needle aspiration biopsy (EUS-FNA/B) can be automated by use of artificial intelligence (AI) techniques based on convolutional neural networks (CNN). We aimed to test the technical feasibility of a novel real-time AI-powered EUS imaging analysis software for detection and segmentation of the pancreas, cystic pancreatic lesions and/or solid pancreatic masses (PANC-AI).
Risk Stratification for BD-IPMN Malignant Transformation. The role of operative dimensional grouping in the cost-effectiveness optimization of surveillance guidelines. The PACMANS Study
Authors: S. Kayali, E. Marabotto, S. Dibitetto, F. Gaiani, A. Busatto, S. Caprioli, A. P. Luzzi, E. Savarino, L. Laghi, C. De Angelis, E. G. Giannini
Journal: Endoscopy (2024)

Aims In recent years, the detection of Branch Duct Intraductal Papillary Mucinous Neoplasms (BD-IPMN) has increased. The Association of Pancreatology (IAP) approved specific guidelines for their management in Fukuoka in 2017. The rates of malignant degeneration of these lesions remain unclear, raising concerns about the cost-effectiveness of the suggested surveillance strategies. This study aimed to identify the rates of BD-IPMN malignant degeneration and their associated risk factors to propose a new, more cost-effective surveillance strategy.
Effect of the Self-Assembling Peptide Solution Treatment on Healing and Prevention of Delayed Bleeding from Post-Resection Defect after Advanced Endoscopy Therapy in GI Tract
Authors: S. Suchanek, T. Grega, N. Brodyuk, Z. Vackova, J. Bures, P. Urbanek, M. Zavoral
Journal: Endoscopy (2024)

Aims After endoscopic mucosal resection (EMR) or endoscopic submucosal dissection (ESD) for non-pedunculated lesions in GI tract the mucosal or submucosal defect is created. It can be treated by monopolar coagulation or clip closure. Recently new method using the self-assembling peptide (SAP) has been introduced. SAP forms the nanofibers web andthe extracellular matrix resulting in three outcomes: acute bleeding hemostasis, delayed bleeding reduction andimproved post-resection defect healing.
Insights into Endoscopic Management and outcomes for Acute Upper Gastrointestinal Bleeding: A Prospective Multicentre UK audit of 5000 patients
Authors: G. Nigam, P. Davies, P. Dhiman, L. Estcourt, J. Grant-Casey, E. Ratcliffe, R. Uberoi, B. Kumar, K. Oakland, M. F. Murphy, J. A. Leithead, A. Douds, V. Jairath, S. Travis, J. Morris, S. Hearnshaw, A. Stanley
Journal: Endoscopy (2024)

Aims Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency. We present the findings on endoscopic management of AUGIB patients in the UK.
A multicentre retrospective cohort study to compare the safety and efficacy of zenker per-oral endoscopic myotomy, flexible diverticulotomy, and rigid diverticulotomy for the management of zenker’s diverticulum
Authors: B. Norton, K. Siggens, A. Papaefthymiou, A. Telese, M. Duku, A. Murino, C. Murray, G. Johnson, B. Mohammadi, M. Mughal, R. Bisschops, P. Bhandari, M. Birchall, R. Haidry
Journal: Endoscopy (2024)

Aims A Zenker diverticulum (ZD) is a herniation of the posterior pharyngeal wall, which is characterised by oropharyngeal dysphagia and regurgitation. Treatment aims to dissect the muscular septum of the cricopharyngeus to create a common cavity with the oesophageal lumen. Historically the main treatment has been surgical, but minimally invasive flexible endoscopic options have emerged as highly successful and safe treatments with the perceived advantage of a more precise and complete myotomy. However, there is no consensus on the gold-standard approach with limited data comparing techniques. We conducted a UK-based retrospective cohort study comparing the safety and efficacy of Zenker per-oral endoscopic myotomy (Z-POEM), flexible diverticulotomy (FD), and rigid surgical diverticulotomy (RD) for management of ZD.
Is additional acetic acid chromoendoscopy effective for prediction of histology of submucosal invasion depth in colonic neoplasms?
Authors: S. Yamamoto, B. Pradeep, P. B. Adolfo, Y. Takeuchi, T. Kanesaka, N. Mottacki, S. Harada, M. Kozuki, R. Higashiura, T. Inoue, R. Sakamori, E. Mita
Journal: Endoscopy (2024)

Aims Acetic acid visualizes the detailed surface of the colonic polyps when combined with image-enhanced endoscopy (IEE). We have reported its ability to enhance pit pattern as an acetoelectronic chromoendoscopy (AEC). Although AEC is expected to be helpful in the pretreatment inspection of colonic neoplasms, including the degree of submucosal invasion, the efficacy of AEC has not been thoroughly investigated. Our aim is to validate the diagnostic value of adding AEC to conventional observation (CO) by physicians with various background experiences in pretreatment assessment of colonic neoplasms, including submucosal invasive lesions.
Premedication with a novel cleansing solution containing simethicone, N-acetylcysteine and acetic acid improves visualization during upper GI endoscopy: a double-blind, multicenter, randomized controlled trial
Authors: M. Manno, G. Gibiino, N. Gualandi, M. Secco, P. Soriani, A. Cucchetti, V. Zadro, C. Binda, P. Biancheri, C. Fabbri
Journal: Endoscopy (2024)

Aims Esophagogastroduodenoscopy (EGDS) is the gold standard examination for upper GI disease diagnosis. Intraluminal presence of bubbles and mucus may reduce visibility and potentially impair lesion detection. It has been shown that the administration of mucolytic and tensioactive agents before EGDS can improve gastric visualization. Hence, we performed a randomized controlled trial (RCT) testing the effect of premedication with a novel solution containing simethicone, N-acetylcysteine and acetic acid on whole upper GI tract visualization.
Salvage Endoscopic Submucosal Dissection After Chemoradiation For Locally Advanced Rectal Adenocarcinoma – Two-year Follow-up
Authors: M. Koseki, L. Galen, M. Nishimura, N. Hingorani, S. Satoi, I. H. Lin, M. Weiser, J. Garcia Aguilar, E. Pappou, P. Paty, M. A. Schattner
Journal: Endoscopy (2024)

Aims The standard treatment of locally advanced rectal cancer is chemoradiation (CRT) followed by proctectomy. However, given an emerging role for nonsurgical management after CRT, endoscopic submucosal dissection (ESD) after CRT, termed salvage ESD, may be an option for carefully selected patients. We aimed to evaluate the long-term clinical outcomes of salvage ESD compared to surgical proctectomy after CRT for locally advanced rectal cancer.
Impact of inter-laboratory variation in detection of lymphovascular invasion (LVI) on treatment and oncological outcomes of T1 colorectal cancer (CRC) patients: a Dutch nationwide cohort study
Authors: L. van der Schee, A. Verbeeck, I. Deckers, C. Kuijpers, J. Offerhaus, T. Seerden, F. Vleggaar, L. Brosens, L.M. G. Moons, P. Snaebjornsson, M. Lacle
Journal: Endoscopy (2024)

Aims Lymphovascular invasion (LVI) plays an important role in determining the risk of lymph node metastasis (LNM) in T1 colorectal cancer (CRC) patients. The presence or absence of LVI guides treatment decisions and subsequently influences patient outcomes. However, the extent to which inter-laboratory variation in LVI detection affects treatment patterns and oncological outcomes is unclear. This study aimed to assess the impact of variation in detection of LVI among Dutch laboratories on the treatment and oncological outcomes of patients with T1 CRC.
Sling-fiber preservation POEM and post-POEM GERD symptoms
Authors: K. Khalaf, Y. Fujiyoshi, M.R. A. Fujiyoshi, G. May, C. Teshima
Journal: Endoscopy (2024)

Aims Peroral endoscopic myotomy (POEM) is standard treatment for achalasia. Gastroesophageal reflux disease (GERD) after POEM has been a limiting factor with this procedure. Preservation of the sling fiber during POEM was reported to reduce post-POEM GERD in Japan, but there are no reports of this technique in a western population. The aim is to investigate the association of sling-fiber preservation during POEM and post-POEM GERD symptoms at our institution, which is a large therapeutic endoscopy referral center in Canada.
Timing of Lumen-Apposing Metal Stents removal in pancreatic fluid collections: could we go beyond?
Authors: S. Stigliano, G. Marocchi, B. Neri, F. Baldaro, F. M. Di Matteo
Journal: Endoscopy (2024)

Aims Lumen-apposing metal stents (LAMS) are becoming the mainstay treatment for pancreatic fluid collections (PFC). A 4-weeks interval for LAMS removal has been suggested to avoid adverse events (AEs) but evidences are scarce. Aim of the study is to evaluate the rate of AEs in patients with PFC undergoing LAMS removal<4 weeks and>4 weeks from placement. The secondary aim is to assess the possible factors associated with AEs occurrence.
Prospective evaluation of the performance of the CONECCT tool for histological prediction and therapeutic choice in colorectal lesions: Pro-CONECCT
Authors: M. Pioche, P. Lafeuille, J. Jacques, T. Wallenhorst, J. C. Saurin, J. Rivory
Journal: Endoscopy (2024)

Aims Endoscopic characterisation of colorectal neoplastic lesions is a key element in predicting histology and choosing the most appropriate type of resection. Six classifications are needed to fully characterise the different colorectal lesions. However, it is difficult to use so many diagnostic tools with numerous sub-categories in the 6 existing classifications. For this reason, we have integrated all the validated criteria from the 6 existing classifications into a single table (CONECCT table), which can be used both to predict histology and to propose an appropriate therapeutic strategy. A prospective, multicentre study including all French gastroenterology residents was carried out to demonstrate the educational value of the CONECCT table. This tool significantly improves histological prediction and the therapeutic choice of French interns and gastroenterologists. We would like to carry out a large-scale prospective evaluation to assess the diagnostic performance (quality) of this tool, in order to simplify endoscopic characterisation and enable proper diagnostic and therapeutic management for each type of colorectal lesion.
Flexible Endoscopic Treatment of Zenker Diverticulum: Not-Operating Room Anestesiology (Nora) Long Term Experience Of A Tertiary Center
Authors: R. Maselli, G. franchellucci, A. Capogreco, E. Mastrorocco, D. Massimi, A. N. Mondovì, A. Galtieri, R. de Sire, C. Hassan, C. Ferrari, A. Repici
Journal: Endoscopy (2024)

Aims The study aims to investigate the outcomes of Zenker Diverticulum (ZD) endoscopic treatments (septotomy or Z-POEM or POES) accordingly to different anesthesia techniques: deep sedation (DS), with spontaneous breathing, vs orotracheal intubation (IOT). In particular if ZD treatment under DS can result in non-inferior outcomes compared to IOT.
Adequacy, safety and technical determinants of modified endoscopic ultrasound guided liver biopsy technique: A pilot study
Authors: B. R. Patra, S. Pujalwar, S. Gupta, S. Harindranath, A. Vaidya, T. Laxane, J. Yadav, P. Mane, A. Shukla
Journal: Endoscopy (2024)

Aims Endoscopic ultrasound-guided liver biopsy (EUS-LB) has emerged as a safe alternative to percutaneous route. Tissue acquisition technique related factors as a determinant of specimen yield has not been studied. We adapted a modified technique of EUS-LB to study the adequacy, safety and technical determinants of higher yield.
Nursing care in raising awareness about the importance of participating in national preventing program for colonoscopy
Authors: V. Lovric, K. Bozilovic, J. Erceg
Journal: Endoscopy (2024)

Aims In Croatia, colorectal cancer ranks second in terms of frequency. Approximately 3.000 individuals of both genders are diagnosed annually, with 2.000 of them succumbing to the disease, placing it fifth in terms of mortality causes. Since 2008, Croatia has implemented a National Early Detection Program for colorectal cancer. The programs objective is to identify the disease in its early stages and reduce mortality. Those at higher risk include individuals over 50 years of age, those with a positive family history, a positive test for occult blood in the stool, and those with previously known polypoid changes.
What is the best ultrasound-guided biliary drainage strategy is case of gastric outlet obstruction? A multicenter retrospective study
Authors: T. Beuchard, J. P. Ratone, M. Schaefer, M. Giovannini, R. Legros, F. Caillol, J. B. Chevaux, J. Albouys, H. Lepetit, M. Dahan, M. Barthet, I. Boutellier, M. Gasmi, Y. Dahel, J. M. Gonzalez, J. Jacques
Journal: Endoscopy (2024)

Aims Concomitant biliary obstruction and gastric outlet obstruction (GOO) is a common situation in pancreatobiliary and gastroduodenal neoplasia. GOO leads to frequent endoscopic retrograde cholangiopancreatography (ERCP) biliary stenting failure. Endoscopic duodenal stenting (EDS) is limited by stent obstruction. Therapeutic endoscopic ultrasonography (EUS) development provide new perspectives, for both biliary obstruction (EUS-guided biliary drainage (EUS-BD)) and GOO (EUS-guided gastroenterostomy (EUS-GE)).
Double EUS-guided bypass (DEB) combining hepaticogastrostomy (HGS) and lumen-apposing metal stent duodeno-jejunostomy (LAMS-DJ) for massive hepatolithiasis in Roux-en-Y hepaticojejunostomy (RYHJ)
Authors: A. Martinez-Ortega, D. Sabbagh, M. Cobreros del Caz, N. Marcos-Carrasco, S. J. Fernández Prada, V. Oregel-Aguilar, R. Sánchez-Ocaña, C. De La Serna Higuera, M. Perez-Miranda
Journal: Endoscopy (2024)

Abstract Text Antegrade endoscopic biliary interventions via HGS or retrograde via enteroscopy are possible in RYHJ. EUS-guided transhepatic cholangiography confirmed large hepatolithiasis 4-years after RYHJ. HGS with antimigration FCSEMS is performed for temporary drainage and for jejunal targeting under EUS. Occlusion cholangiogram via HGS provides distention of afferent jejunal limb for EUS-guided access anastomosis by 15x10-mm LAMS placement from the bulb. During subsequent sessions, several gastroscope passages across LAMS-DJ into bile duct are needed for mechanical and cholangioscopy-guided lithotripsy until duct clearance is achieved. Bilateral 7F pigtails are left-in-situ to minimize recurrences. HGS stent is removed. No adverse events (AE) ensued post-procedure sessions, during the treatment period or post-treatment follow-up. Larger disease burden may be addressed by DEB in RYHJ, minimizing AE risk [1] [2].
Assessing the Environmental Impact of Gastrointestinal Endoscopy Procedures at a Tertiary Care Institution in India: A Prospective Study on Waste Generation and Greenhouse Gas Emissions
Authors: H. Rughwani, R. Kalapala, A. katrevula, N. Jagtap, Z. Nabi, N. R. Duvvur
Journal: Endoscopy (2024)

Aims In light of the pressing global challenge posed by climate change in the 21st century, it is important to address the substantial environmental impact of the healthcare sector, with a particular focus on Gastrointestinal Endoscopy (GIE) [1] [2]. GIE procedures involve the extensive use of consumables, contributing significantly to hospital waste and greenhouse gas (GHG) emissions. The primary aim of this research is to accurately measure the GHG emissions associated with GIE procedures in countries with emerging economies.