tbuckley/cabot-search huggingface dataset:
Fellow Perspectives on Interprofessional Teaching in the ICU: A Multicenter Qualitative Study
Authors: M. Theodore, C.R. Petri, C. Beltran, M.E. Bateman, T. Herzog, M. John, L. Kearney, J. Maccarone, K. Pandya, T. Smith, A.M. Anandaiah
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Phenotype Analysis of Chronic Bronchial Infection Patients on Nebulized Antibiotic Therapy: A Multicenter Retrospective Cohort Study in Spain (INBREATHING Study)
Authors: J. Gonzalez, B. Raboso Moreno, I.D. Benítez, M. Erro, J. Burgos, A. Sayés, E.-J. García, C. Pou, R.A. Castañon, A. Navarro, A. Martínez de las fuentes, J.-S. Lakhani, A. Hernández, C. Manzano, S. Santisteve, A. Monge, A. Moncusí-Moix, A. Sánchez-Cucó, A.B. Alcaide, J.P. De Torres Tajos, F. Barbe, G. Suárez, D. de la Rosa
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Unsupervised Machine-learned Discovery of Quantitative Airway Tree Subtypes and Their Association With Chronic Obstructive Pulmonary Disease Endpoints: The Multi-Ethnic Study of Atherosclerosis Lung Study
Authors: S. Naik, E.D. Angelini, Y. Sun, E.A. Hoffman, N.B. Allen, A. Bertoni, A.W. Manichaikul, O. O'Driscoll, J.S. Pankow, W. Post, K.E. Watson, A.F. Laine, R.G.G. Barr, B.M. Smith
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Association of Contrast Enhanced Dual Energy CT-derived Pulmonary Arterial Tree-to-Lung Ratio (ArtLR) With COPD
Authors: S. Hosseini, J. Orr, N. Newcomb, M. Dunn, J. Leininger, J. Guo, S.E. Gerard, A.P. Comellas, M. jacob, J. schroeder, P. Woodruff, J.L. Curtis, J.M. Reinhardt, E.A. Hermann, R.G.G. Barr, B.M. Smith, N.N. Hansel, M.K. Han, E.A. Hoffman
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
AP1 Regulates the Expression of Aryl Hydrocarbon Receptor in Asthmatic Airway Smooth Muscle
Authors: M.I. Reza, P. Balraj, C. Tandberg, J. Walum, Y.S. Prakash, C.M. Pabelick, R.D. Britt, V. Sathish
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Are Pulmonologists Better Than Validated Prediction Models for Pulmonary Nodules Referred for Biopsy: A Secondary Analysis of the Reliant Randomized Controlled Trial
Authors: K.M. Leonard, T.K. Boyle, H. Chen, B. Swanner, G.J. Dahlberg, A.P. Ratwani, J.D. Duke, R. Paez, S. Shojaee, R.J. Lentz, F. Maldonado
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Spatially Resolved Transcriptomics Identifies Age-related Pathological Niches During Recovery From Viral Pneumonia
Authors: L. Morales-Nebreda, M. Jovisic, R. Nafikova, I. Hawkins, M. Schleck, G. Rerko, A. Sivakumar, E. Kao, H. Abdala-Valencia, L. Villa-Ellis
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Computational Fluid Dynamics Analysis of Tracheal Pressure Difference in Neonates With Tracheoesophageal Fistulas Before and After Surgical Repair
Authors: C. Boles, C.C. Gunatilaka, Q. Xiao, J.C. Woods, P.S. Kingma, N.S. Higano, A. Bates
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Effect of Adherence to Inhaled Pharmacologic Therapy on Chronic Obstructive Pulmonary Disease (COPD) Exacerbations and Death Among U.S. Veterans
Authors: M. Chee, L.M. Donovan, F. Picazo, A.G. Leonhard, K. Duan, D.H. Au, L.C. Feemster
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Improvements in Asthma Exacerbations, Lung Function, Asthma Control and Health-related Quality of Life After Tezepelumab Initiation in Patients With Severe Asthma: Interim Results From the US Phase 4 PASSAGE Study
Authors: N.L. Lugogo, P. Akuthota, K. Sumino, A.F. Burnette, S.K. Mathur, A.W. Lindsley, J.-P. Llanos Ackert, C. Marchese, C.S. Ambrose, B. Emmanuel
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Distinct Proteomic Profiles in Anti-Jo-1 Versus Non-Jo-1 Idiopathic Inflammatory Myopathy Patients: Implications for Interstitial Lung Disease Risk
Authors: J.A. Huapaya, H. Wang, P. Burbelo, I. Pinal-Fernandez, M. Casal-Dominguez, X. Tian, S. Gairhe, P. Noroozi Farhadi, K. Sarkar, A. Schiffenbauer, S.K. Danoff, L. Rider, A. Mammen, A.F. Suffredini
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Dupilumab Improves Lung Function, Asthma Control and Exacerbation Frequency in Allergic Bronchopulmonary Aspergillosis - Results From the Phase 2 LIBERTY ABPA AIRED Study
Authors: A. Bourdin, J. Corren, A. Shah, C.G. Baxter, L. Davidescu, N. Amin, H. Paleczny, J. Chiarappa, A.P. Fontenot, P. Dakin, E. Laws, J. Maloney, L. Wright-Bello, A. Radin
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Ethnic Differences in the Respiratory Microbiome and Transcriptome in Children With CF and CRMS
Authors: M.E. Mcgarry, K. Tuveson, M. Hernandez, A. Quinn, L. Swander, M. Simon, J. Blum, H. Kim, T.A. Laguna, M. Zinter
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Distinct Air Pollutant Exposures in Patients With Bronchiectasis Are Associated With Differences in Airway Microbiome
Authors: I. Atandi, R.C. Flowers, A.E. Imperato, K. Erlandson, D. Collazo, C.R. Barnett, C. Rodriguez, K. Krolikowski, G. Porter, Y. Feng, Y. Kyeremateng, C. Mccormick, A. Czachor, R. Schluger, M. Chang, F. Darawshy, I. Sulaiman, Y. Li, B.G. Wu, T. Gordon, G.D. Thurston, D.L. Kamelhar, D.J. Addrizzo-Harris, A. Basavaraj, S. Singh, L.N. Segal
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Gut Bacterial Lactic Acid Stimulates Lung Epithelial Mitochondria and Exacerbates Acute Lung Injury
Authors: V. Upadhyay, G. Kaur, E.F. Ortega, K. Trepka, R.R. Rock, L. Ramirez Hernandez, W.C. Cheshire, N. Alipanah-Lechner, C.S. Calfee, M.A. Matthay, S. Blume, I. Jain, P.J. Turnbaugh
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Impact of Fluticasone Furoate/Umeclidinium/Vilanterol Inhaled Therapy on a Clinical Remission Endpoint in Asthma for Patients with Type 2 Inflammation: CAPTAIN Post Hoc Analysis
Authors: I.D. Pavord, J. Crawford, S. Gould, A. Moore, S.G. Noorduyn, D. Slade, S. Weng, J. Oppenheimer
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Long-term Treatment of Single-tablet Combination of Macitentan and Tadalafil in Pulmonary Arterial Hypertension (PAH): Final Results From the A DUE Open-label Extension
Authors: H.J. Ford, K.M. Chin, F. Fan, M. Friberg, E. Grünig, J.A. Hauser, M. Pannaux, H. Rofael, P. Jansa
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Fulminant Myocarditis and Encephalitis Associated With Human Metapneumovirus in an Immunocompetent Adult: A Case Report
Authors: L.M. Castillo Morales, C.A. Pérez-Velázquez, L.E. Maestre-Carrillo, J. Alvarado, C. Rodríguez Gómez, H.M.M. Cortes Aguilera
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Exploring the Impact of Inflammation on Gas Exchange Efficiency in Cannabis-smoking Individuals Using <sup>129</sup>XeMRI
Authors: J. Liggins, C. Gilchrist, A. Schmidt, S. Mostafavi, X. Li, F.V. Gerayeli, A. Hsu, C. Leung, J. Guenette, J.H. Rayment, J.A. Leipsic, D.D. Sin, J.M. Leung, R.L. Eddy
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Reduced treatment response to inhaled corticosteroids in current smokers with COPD, regardless of blood eosinophil count: insights from the FLAME trial
Authors: Alexander G Mathioudakis, Andrew Higham, Sebastian Bate, Victoria Chatzimavridou-Grigoriadou, Pradeesh Sivapalan, Jens-Ulrik Stæhr Jensen, Tim Felton, Jørgen Vestbo, Dave Singh
Journal: Thorax (2025)

Inhaled corticosteroids (ICSs) benefit patients with chronic obstructive pulmonary disease at high risk of exacerbations with raised blood eosinophil count (BEC). Emerging evidence suggests current smokers show a reduced response to ICS. This post-hoc analysis of the FLAME trial explored the impact of smoking status on the efficacy of long-acting beta-2 agonist (LABA)+ICS versus LABA+long-acting muscarinic antagonist (LAMA) for preventing exacerbations. Our findings indicate that LABA+LAMA is superior to LABA+ICS in preventing moderate to severe exacerbations in current smokers and inferior in ex-smokers with BEC ≥200 cells/µL. Smoking status significantly modifies ICS treatment effects on exacerbation outcomes, suggesting reduced ICS efficacy in current smokers, regardless of BEC.
The Estimated Impact of Respiratory Syncytial Virus Lower Respiratory Tract Disease and Prevention on Chronic Lung Disease in Children in the United States
Authors: I.M. Galbreath, M.C. Fitzpatrick, A.M. Larocco, S.M. Brunwasser, B.M. Snyder, T.V. Hartert, D.W. Hutton, J.R. Ortiz
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Performance of the Pediatric Asthma Impairment and Risk Questionnaire (Peds-AIRQ) in Assessing Control Relative to the Pediatric Quality of Life Inventory (PedsQL) and Patient Impression of Control
Authors: M. George, B.E. Chipps, K.R. Murphy, M.J. Lanz, L.B. Bacharier, R.S. Zeiger, T.W. Guilbert, A. Mohammad, M. LeNoir, I.A. Gilbert, J.M. Eudicone, M.K. Ladd, G. Harding, T. Winders
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
A Case of Triple Diagnosis on Video-Assisted Thoracoscopic Surgery (VATS)
Authors: S.M.A. Naqvi, A. Ahmed, J. Wortsman, H. Tokashiki, A.S. Copur, H.S. Bawaadam, S.M. Nanavati, R. Lenhardt
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Comparative Gene Expression Analysis in Influenza Associated Invasive Pulmonary Aspergillosis and Post-influenza Staphylococcal Aureus Pneumonia
Authors: N. Naghshtabrizi, K. Nickolich, D. Rajasundaram, M.E. Snyder, J.F. Alcorn, K.M. Robinson
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Acute Encephalitis and Myocarditis Due to Immune Checkpoint Inhibitor Toxicity
Authors: O. Rahman, N. Wiseman, F. Shafiq, A. Greenspan, A. Tahir, R. Saeed, S. Khan, D. Ahmed, F. Afzal, H. Khan, A. Aamir, H. Khan, A. Sharif, Z. Younas, F. Alam, H. Siddiqui, S.N. Aamer, M. Iqbal
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Rapidly Improving Acute Respiratory Distress Syndrome (ARDS) Is Common and Unique in Sepsis-related ARDS
Authors: P.L. Valda Toro, K. Housel, N.S. Bishop, R.M. Bennett, C.A.G. Ittner, T. Miano, G. Emre, M. Erlich, M. Esperanza, B. Karanam, T.K. Jones, M.G.S. Shashaty, G.E. Weissman, R. Feng, J.P. Reilly, N.J. Meyer
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Effects of Immunomodulatory Fatty Acids on Lung Function Are Mediated Through Smoking-related Differences in DNA Methylation
Authors: B.K. Patchen, Y. Huang, E.K. Phillips, O. Rafique, W.-Y. Saw, K.H. Shutta, C.M. Lopes-Ramos, G. Menichetti, D.B. Hancock, P.A. Cassano, D.L. Demeo
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Changes in Cardiometabolic Risk Factors Based on Improvements in Apnea-Hypopnea Index in Participants From the SURMOUNT-OSA Clinical Studies
Authors: R. Mehra, A. Malhotra, C. Xie, S. Chakladar, B. Liao, J. Bednarik, B. Falcon
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Granulocyte-macrophage Colony-stimulating Factor Drives Lung Repair After Severe Influenza Virus Pneumonia by Reprogramming Alveolar Epithelial Progenitor Cell States
Authors: T. Schäfer, A.I. Vazquez Armendariz, L. Sperling, I. Alexopoulos, M. Heiner, T. Hain, M. Bartkuhn, E. El Agha, S. Herold
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Sex-Specific Temporal Changes in Systemic and Pulmonary Immune Responses to Traffic-Related Air Pollution Components in a Transgenic Rat Model of Alzheimer's Disease
Authors: H.H. Park, M.-Y. Cheng, V.E. Anthony, M. Domanico, A. Ikeda, K.J. Bein, L.S. Van Winkle, P.J. Lein
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Effects of Obstructive Sleep Apnea Treatment on Cardiovascular and Sleep Health in Same-Bed Sleep Partners: The SLEEP PARTNERS Randomized Trial
Authors: S. Giampá, S.F. Furlan, T.A. Macedo, F.C.S.G. Cruz, M.L. Cabrini, S. Barros, I.F.B. Azam, V. Costa-Hong, L.A. Bortolotto, G. Lorenzi-Filho, L.F. Drager
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Deriving an Equation to Predict Peak Power Output From the Six-minute Walk Distance for Pulmonary Hypertension Patients
Authors: N. Morris, H.E. Seale, J.F. Feenstra, M. Trotter, A. Lin, C.R. Aitken, M. Louis, J.A. Adsett, F.K. O'Connor
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Effect of Repeated Jet Fuel Exposure on Human Bronchial Epithelial Cells as Measured by VOCs
Authors: K. Aribindi, A. Linderholm, E. Borras, D.E. Rojas, M.M. Mccartney, C.E. Davis, R.W. Harper, N.J. Kenyon
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
MerTK Is Cleaved From Alveolar Macrophages Following Exposure to Ozone
Authors: J.M. Radbel, P. Zhou, A. Lemenze, C. Gardner, K. Black, A. De Resende, J. Laskin, H.M. Kipen, A.J. Gow, D.L. Laskin
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Early Phase Double-blind, Placebo-controlled Study of Medium Chain Triglycerides Additive in Adult Asthma
Authors: S.A.A. Comhair, Y. Hou, K. Asosingh, B. Beck, M.M. Koo, D. Mavrakis, L. Peterson, F. Cheng, T. Rutherford, K. Hambleton, J. Kirwan, S.C. Erzurum
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
SARS-CoV-2 Spike Protein, SARS-CoV-2 Nucleocapsid Protein, and HIV GP120 Protein From Human BAL Are Contained Within Extracellular Vesicles and as Free Protein
Authors: M.E. Fraser, P. Smith, A. Belanger, T. Shinabery, R. Elmergawy, L. Guang-Sheng, R. Patel, H. Wynn, M. Clauss, R. Relich, H.L. Twigg
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Clinical Outcomes After Switching From Metered-Dose Inhaler Budesonide-Formoterol to Dry-Powder Inhaler Fluticasone-Salmeterol in a Nationwide Veteran Cohort
Authors: A. Rabin, S.M. Seelye, J.B. Weinstein, C.K. Hogan, T.N. Whittington, J. Cano, C. Kelley, H.C. Prescott
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Two-year Efficacy and Safety of Benralizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis
Authors: M.E. Wechsler, P. Nair, N. Khalidi, B. Terrier, B. Hellmich, A. Bourdin, D.R.W. Jayne, D.J. Jackson, F. Roufosse, C. Pagnoux, U. Specks, L. Börjesson Sjö, C.N. Ho, M. Jison, C. McCrae, S. Necander, E. Rodríguez-Suárez, A. Shavit, C. Walton, P.A. Merkel
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
An Epigenetic Association Between Heightened Airway Hyperreactivity and Maternal Exposure to Particulate Air Pollution
Authors: R. Zakarya, Y.L. Chan, B. Wang, A. Thorpe, D. Xenaki, K.F. Ho, H. Guo, H. Chen, B. Oliver, C. O'Neill
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Lung Cancer Screening Eligibility, Uptake, and Adherence in Puerto Rico, 2022
Authors: E.R. Nunez, E. Santiago-Rodríguez, W. Rodriguez, C. Olazagasti, E. Flores, A. Velázquez Mañana, Y. Otero, M. Castañeda-Avila
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Sustained Efficacy of Depemokimab Over Time in Type 2 Asthma Characterized by Blood Eosinophils: Pooled Data From the Phase III SWIFT-1/2 Studies
Authors: M.E. Wechsler, R.A. Panettieri, D. Muccino, R. Forth, J. Kwiatek, A. Vichiendilokkul, D.J. Jackson
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Allergic Sensitization in Asthma and/or COPD in the NOVELTY Study
Authors: C. Janson, A. Malinovschi, M. Borres, R. Faner, R. Hughes, A. Mangelis, H. Müllerová, A. Papi, H.K. Reddel, J.M.M. Olaguíbel, None for the NOVELTY Scientific Community and the NOVELTY study i
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Extracellular-vesicles From Bone Marrow Mesenchymal (MSC-EVs) and Adipose (ASC-EVs) Stem-cells Improve Barrier Integrity and Restore Redox Balance in a Lung Epithelial-Endothelial Model
Authors: A. Burello, J. Kopecka, S. Scrivanti, A. Scagliotti, E. Candiello, M.A.C.A.C. Pomatto, C. Gai, A. Costamagna, P. Cappello, G. Castellano, V. Cantaluppi, C. Riganti, G. Camussi, V. Fanelli
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Integrating Technologies: Multimodal Monitoring With NIRS and Electroencephalography for Optimization of Perioperative Management of Intracranial Hemorrhage
Authors: M. Parada, C. Niño, D. Cohen, J. Mejia, Y. Feliz, D. Benitez, W. Amaya, J. Martinez, G. Montoya
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Mechanisms of Anti-IL5RαTherapy Restoring Nasal Epithelial Cell Barrier Function in Severe Eosinophilic Asthma
Authors: K.L. Raby, H. Li, P. Dixey, J.B. Koranteng, K.F. Chung, P.K. Bhavsar
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Small Airways or Big Lungs? Investigating the Structural Components of Dysanapsis and Their Associations With Obstructive Lung Physiology at Rest and During Exercise
Authors: None Collins, D. Jensen, M. Kirby, D.B. Phillips, Y. Molgat-Seon, D.D. Marciniuk, B. Walker, S.D. Aaron, P. Hernandez, W.-C. Tan, J. Bourbeau, B.M. Smith, None CanCOLD Collaborative Research Group, None Canadian Respiratory Research Network
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Nasal Transcriptomics Associate With Sinonasal Disease Response to Trikafta
Authors: D.J. Weiner, M. Yue, L. Zhou, S. McCabe, Y.-Y. Han, C.M. Qoyawayma, M. Manni, A. Stapleton, M. Myerburg, J.M. Pilewski, J.C. Celedon, W. Chen, E. Forno
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
National Trends and Disparities in ARDS Mortality: An Analysis of CDC WONDER Data (1999-2020)
Authors: A.B.M.N. Alam, F. Zarah, B. Adeyemi, O. Fatunmbi, J.A. Galindo Castaneda, C. Khudari, J. Jacobson-Cherry, T. Islam
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Establishing Lung Cancer Risk and Optimizing Incidental Pulmonary Nodule Management
Authors: M. Brown, C. Bartolomeu, H. Lam, S.A. Borden, K. Kiland, L. Martins, D. Estevam, A. Walker, W. Parker, L.Y.W. Shong, S. Lam, R. Myers
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Proteomics of CT Emphysema Subtypes in the General Population. The Multi-Ethnic Study of Atherosclerosis (MESA) Lung Study
Authors: D.E. Guzman, Y. Sun, T. Pottinger, W. Post, A.G. Bertoni, N.B. Allen, W.C. Johnson, K.E. Watson, J.S. Pankow, A.W. Manichaikul, E.A. Hoffman, R. Dubin, R. Deo, E. Oelsner, E. Angelini, A. Laine, V.E. Ortega, R.P. Bowler, P. Ganz, R.G.G. Barr
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Upper and Lower Respiratory Microbiome-Transcriptome Concordance in Pediatric Hematopoietic Stem Cell Transplant Patients
Authors: E.M. Evans, E.M. Pearce, M.Y. Mayday, G. Reyes, M.R. Simon, H. Kim, C.C. Dvorak, J.L. Derisi, M.S. Zinter
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Releasing the Brakes in IPF: Inflammatory Fibroblasts Alter the Alveolar Niche to Promote Epithelial Expansion
Authors: L.R. Rodriguez, W.J. Roque Barboza, A.M. Diaz Espinosa, A. Murthy, S. Bui, Y. Tomer, C. Cooper, R. Chroneos, A. Reineberg, D.J. Tschumperlin, M.F. Beers
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Myeloid Cell-specific Ablation of Caspase 8 Improves Outcomes in Influenza A-induced Acute Respiratory Distress Syndrome
Authors: G.W. Tan, C.M. Vaswani, J.L. Pavelick, S.S. Batah, J.N. Tsoporis, J.C. Marshall, C.C. Dos Santos
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Cancer Outcomes in the Watch the Spot Trial: A Pragmatic Clinical Trial of Less Compared With More Intensive Strategies for Active Surveillance of Patients With Small Pulmonary Nodules
Authors: M.K. Gould, B. Creekmur, L. Qi, E. de Bie, K. Kelly, R. Smith-Bindman, D.L. Miglioretti, None for the Watch the Spot Investigators
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Severe Hypoglycemia and High Anion Gap Metabolic Acidosis Due to Severe Type B Lactic Acidosis as a Metabolic Decompensation of Glycogen Storage Disease Type 1a (Von Gierke Disease)
Authors: Z. Younas, K. Jethani, A. Shenoy, M. Chaudhary, N. Patel
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Sources of Bias in AI Models: Variation in Sepsis Monitoring: Lactate Measurement in the ICU
Authors: N. Abu Hussein, P. Pradhan, F.W. Haug, D. Moukheiber, L. Moukheiber, M. Moukheiber, S. Moukheiber, J.G. Ellen, H. D'Couto, I.C. Williams, L.A. Celi, J. Matos, T. Struja
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Alpha-1 Antitrypsin - A Prognostic Factor in Acute Respiratory Distress Syndrome
Authors: O.F. Mcelvaney, T.P. Carroll, M. Herron, M. Casey, D. Fraughen, O.J. Mcelvaney, M.P. Murphy, J. Clarke, N.L. Mcevoy, S. Walsh, G. Curley, N.G. Mc Elvaney
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
The March to Harmonized Imaging Standards for Retinal Imaging
Authors: Nayoon Gim, Alina N Ferguson, Marian Blazes, Cecilia S Lee, Aaron Y Lee
Journal: Progress in Retinal and Eye Research (2025)

The adoption of standardized imaging protocols in retinal imaging is critical to overcoming challenges posed by fragmented data formats across devices and manufacturers. The lack of standardization hinders clinical interoperability, collaborative research, and the development of artificial intelligence (AI) models that depend on large, high-quality datasets. The Digital Imaging and Communication in Medicine (DICOM) standard offers a robust solution for ensuring interoperability in medical imaging. Although DICOM is widely utilized in radiology and cardiology, its adoption in ophthalmology remains limited. Retinal imaging modalities such as optical coherence tomography (OCT), fundus photography, and OCT angiography (OCTA) have revolutionized retinal disease management but are constrained by proprietary and non-standardized formats. This review underscores the necessity for harmonized imaging standards in ophthalmology, detailing DICOM standards for retinal imaging including ophthalmic photography (OP), OCT, and OCTA, and their requisite metadata information. Additionally, the potential of DICOM standardization for advancing AI applications in ophthalmology is explored. A notable example is the Artificial Intelligence Ready and Equitable Atlas for Diabetes Insights (AI-READI) dataset, the first publicly available standards-compliant DICOM retinal imaging dataset. This dataset encompasses diverse retinal imaging modalities, including color fundus photography, infrared, autofluorescence, OCT, and OCTA. By leveraging multimodal retinal imaging, AI-READI provides a transformative resource for studying diabetes and its complications, setting a blueprint for future datasets aimed at harmonizing imaging formats and enabling AI-driven breakthroughs in ophthalmology. Our manuscript also addresses challenges in retinal imaging for diabetic patients, retinal imaging-based AI applications for studying diabetes, and potential advancements in retinal imaging standardization.
A Novel and Clinically Relevant Model of Maternal ARDS to Understand Critical Maternal Fetal Interactions
Authors: M.J. Lim, X. Li, D. Sankaran, E. Guisto, R. Valdez, A. Lesneski, M. Persiani, V. Hammitt, E. Riley, M.A. Matthay, S. Lakshminrusimha, K.E. Pinkerton
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Automated Screening of Electronic Medical Records to Detect the Next Pandemic
Authors: W. Thinnes, G. Cloherty, F. Averhoff, M. Berg, J.C. Rojas, D. Van Aartsen, K.E. Jackson, J. Moy, A. Gosha, A. Landay, R.A. Balk
Journal: American Journal of Respiratory and Critical Care Medicine (2025)
Machine Learning-Based Prediction of Clinical Improvement in COVID-19 Pneumonia Patients at Hospital Admission: A Secondary Analysis of a Randomized Clinical Trial
Authors: P.L. Silva, C.C.S.D. ConceiÇão, C.M. Martins, E.E. Silva, M.M. Silva, H.C.D.C.F. Neto, P.R.M. Rocco, F.F. Cruz
Journal: American Journal of Respiratory and Critical Care Medicine (2025)