Dapagliflozin for Critically Ill Patients With Acute Organ Dysfunction
Authors: Caio A. M. Tavares, Luciano C. P. Azevedo, Álvaro Rea-Neto, Niklas S. Campos, Cristina P. Amendola, Amanda C. Kozesinski-Nakatani, Paula G. David-João, Suzana M. Lobo, Thiago C. Filiponi, Guacyra M. B. Almeida, Ricardo R. Bergo, Mário R. R. Guimarães-Júnior, Rodrigo C. Figueiredo, Joan R. Castro, Clewer J. Schuler, Glauco A. Westphal, Ana C. R. Carioca, Frederico Monfradini, Josue Nieri, Flavia M. O. Neves, Jaqueline A. Paulo, Camila S. N. Albuquerque, Mariana C. R. Silva, Mikhail N. Kosiborod, Adriano J. Pereira, Lucas P. Damiani, Thiago D. Corrêa, Ary Serpa-Neto, Otavio Berwanger, Fernando G. Zampieri, Juliano Souza, Luciana Sanches, Maisa Castro, Mariana Cunha, Flávia Fagundes, Juan Siqueira, Glauco Westphal, Cristian Ospina, Evelin Silva, Juliano Ramos, Miriam Machado, Ruthy Fermamdes, Camila Lunardi, Luana Radun, Andervan Moura, Evanio Silva, Livia Dantas, Livia Gomes, Maria Luzia Silva, Yolanda Nunes, Ana Beatriz Lino, Gabrielly Barros, João Pedro Nunes, Marivalda Barbosa, Guilherme Souza, Hugo Duarte, Hannah Mota, Joan Castro, Mayler Olambrada, Rafael Borges, Luciana Barros, Nelson Pereira, Marcos Tavares, Gabriela Joia, Gabriella Cordeiro, Natalia Mattos, Vinicius Lanza, Victoria Silva, Marianna A Dracoulakis, Natalia Alvaia, Camilla Vieira, Izabela Freitas, Beatriz Conceição, Jaqueline Borges, Aline Silva, Thais Caroline, Josiane Jesus, Allan Santos, Bruno Vieira, Isabelle Guerreiro, Luciana Oliveira, Luiz Esteves, Rodrigo Bolini, Edmilson Carvalho, Adilson Lacerda, Aline Ferreira, Gustavo Sica, Lara Oliveira, Maria das Vitórias Guedes, Otavio Gebara, Ana Paula Espirito Santo, Ana Tarina Lopes, Hevelton Ribeiro, Pablo Tomba, Vislaine Morete, Joyce Almeida, Claudia Silva, Luana Gato, Leticia Inada, Claire Dias, Frederico Dall’Orto, Graziela Melo, Ana Roberta Silva, Gislayne Ribeiro, Kemilys Ferreira, Rodrigo Biondi, Sergio Ramalho, Derick Silva, Eduardo Garbin, Ingrid Pereira, Luana Nunes, Rayane Lacourt, Cintia Loss, Jackelyne Silva, Claudio Jorge, Graziela Denerdin, Karla Millani, Luana Machado, Ana Carolina Affonso, Juliane Garcia, Tatiane Oiafuso, Luana Camargo, Kaio Morais, Aline Angeli, Cassia Pradela, Gustava Marques, Joelma Silva, Maria Fernanda Santos, Marina Zini, Keulle Candido, Tamires Silva, Verônica Barros, Mariana Pool, Fabio Serra, Alef Coelho, Lea Vieira, Tamyres Galvao, Alexandre Tognon, Marcos Dozza, Sabrina Henrich, Andressa Giordani, Aloma Menegasso, Murillo Antunes, Nicoli Gosmano, Stefany Moura, Tiberio Costa, Vitoria Canato, Gabriela Queiroz, Mariana Gonçalvez, Mariana Zanona, Hellen Dias, Eduardo Bazanelli Junqueira Ferraz, Caroline Rossi, Leandro Pozzo, Diogo Moia, Ronaldo Vicente Pereira Soares, Ramy Machado Marino, Bruna Ladeira Moreno, Arthur Serapião, Roberta Momesso, Bárbara Gomes da Silva, Cintia Selles Santos, Elaine de Jesus Santos, Bruna dos Santos Sampaio, Luciana Pereira Almeida de Piano
Journal: JAMA (2024)

Sodium-glucose cotransporter 2 (SGLT-2) inhibitors improve outcomes in patients with type 2 diabetes, heart failure, and chronic kidney disease, but their effect on outcomes of critically ill patients with organ failure is unknown.