tbuckley/cabot-search huggingface dataset:
Clinical and performance outcomes of colorectal submucosal dissections using a novel advanced energy platform: a single prospective cohort observational study
Authors: Z. Tsiamoulos, M. Abbas, N. Bagla, R. Vega, E. Albéniz, M. Ramchandani, P. B. Adolfo, J. Sebatian, S. Zeidan
Journal: Endoscopy (2024)

Aims This single centre prospective observational study aims to measure clinical and performance outcomes using the Speedboat 10fr Inject device/SBI, and the Speedboat-assisted Endoscopic Submucosal Dissection/S-ESD modality when removing complex colorectal lesions.
Elderly vs. young patients: clinical, endoscopic and prognostic particularities in case of upper gastrointestinal hemorrhage: prospective study
Authors: C. Jioua, B. Jihane, T. Addajou, R. Berraida, I. Elkoti, R. Fedoua, H. Seddik
Journal: Endoscopy (2024)

Aims Upper GI bleeding (UGI) is the most common reason for emergency hospitalization in hepato-gastroenterology. However, there are not enough studies comparing clinical and endoscopic features between young and elderly patients with upper GI bleeding.
Cancer characteristics in Lynch syndrome: a retrospective study in a large cohort of patients
Authors: P. Cortegoso Valdivia, G. Mistretta, D. Pitoni, M. Pennazio
Journal: Endoscopy (2024)

Aims Lynch syndrome (LS) is an inherited cancer syndrome associated with specific DNA mismatch repair (MMR) defects, accounting for a high risk of developing gastrointestinal (GI) and extra-GI cancers. The aim of this study is to comprehensively analyze the clinical and genetic features of a large cohort of LS patients focusing on mutation profiles and the distribution of GI cancers, including extra-GI ones.
Endoscopic Mucosal Resection (EMR) in Treatment of Colitis Associated Neoplasia (CAN): A Single-Centre Experience From Leuven, Belgium
Authors: N. Panic, S. Vermeire, I. Demedts, H. Willekens, J. P. Guedelha Sabino, D. Tarabar, R. Bisschops
Journal: Endoscopy (2024)

Aims Endoscopic resection has been recommended as preferable therapeutic approach for colitis associated neoplasia (CAN) in inflammatory bowel disease (IBD) patients. However, endoscopic resection of these lesions can be challenging due to ongoing inflammation, mucosal scarring, and submucosal fibrosis. We report long-term, single centre experience on performance of endoscopic mucosal resection (EMRs) for treatment of CANs .
Anorectal variceal bleeding successfully treated with injection of a sclerosing agent used in sclerotherapy of varicose veins of the lower extremities (ethanolamine)
Authors: C. Sotiropoulos, C. Konstantakis, G. Theocharis, C. Triantos, K. Thomopoulos
Journal: Endoscopy (2024)

Abstract Text Anorectal varices are relatively common in patients with portal hypertension. [1] [2] [3] [4] [5]
Endoscopic Mucosal Resection with Argon Plasma Coagulation for a Colonic Laterally Spreading Tumor
Authors: V. Chuabio
Journal: Endoscopy (2024)

Abstract Text A 65-year-old male underwent colonoscopy as investigation for the passage of blood clots per rectum. A 2.5-centimeter laterally growing polypoid lesion with overlying regular tubular mucosal pattern was seen at the sigmoid colon and classified as a nodular mixed type of granular laterally spreading tumor (LST-G). Piecemeal endoscopic mucosal resection (EMR) was done; however, adequate resection margins were not achieved with repeated resections. A meta-analysis has supported endoscopic interventions that target EMR margins to decrease risk of tumor recurrence. Argon plasma coagulation (APC) was thus applied onto the post-resection site until with golden-brown appearance. No post-resection bleeding occurred on follow up after two weeks. Histopathology showed tubular adenoma with high-grade dysplasia. Subsequent plan is to do surveillance endoscopy in six months. [1]
The integrated care pathway (or clinical pathway) in gastrointestinal bleeding: preliminary single center experience
Authors: C. Marmo, V. Ojetti, G. Costamagna, A. Gasbarrini, M. E. Riccioni
Journal: Endoscopy (2024)

Methods This is a retrospective cohort study, we evaluated patients with acute gastrointestinal bleeding for any causes admitted in tertiary care center between January 2022 and September 2022. Data were extracted from electronic health records using ICD-9 algorithm. A descriptive analysis of the data was performed, with a calculation of the mean, median, proportions, standard deviation and 95% confidence limits depending on data type.
Endoscopic full-thickness resection (eFTR) alone vs. combined EMR and endoscopic full-thickness resection (hybrid eFTR) for the treatment of neoplastic colorectal lesions: a retrospective comparative study
Authors: P. Stathopoulos, M. Zumblick, S. Glas, C. Denkert, U. W. Denzer
Journal: Endoscopy (2024)

Aims eFTR is an established procedure for endoscopic resection of non-lifting lesions. A limitation of this technique is the size of the lesion due to the size of the FTRD cap, especially in cases of submucosal scaring by previous treatment. The combination of eFTR with EMR (hybrid eFTR) represents an extension of the method. However, there are still limited data about the efficacy and safety of hybrid eFTR and large comparative studies are lacking.
Eus-tissue acquisition of subepithelial lesions in the new era of FNB needles: a monocentric study
Authors: F. Fimiano, A. Mauriello, M. T. Staiano, E. Dall'Amico, F. Castellano, M. Gesualdo, M. Sacco, C. De Angelis
Journal: Endoscopy (2024)

Aims Gastroenteric subepithelial lesions diagnosis is often a challenge. This study compared the efficacy in terms of sample adequacy that is crucial to perform immunohistochemical techniques for achieving a definitive diagnosis [1], diagnostic capacity, and safety of EUS-FNA and FNB.
Underwater endoscopic mucosal resection for gastric tumours
Authors: J. W. Kim, H. S. Kim, S. Y. Park, D. H. Kim
Journal: Endoscopy (2024)

Aims A submucosal injection before resection of gastric adenomas or polyps could facilitate resection, reduce thermal damage to deeper tissue and decrease the risk of perforation. As an alternative to submucosal injection, underwater endoscopic mucosal resection (UEMR) is widely used for colorectal and duodenal tumours. UEMR for gastric tumours has not been well reported. We therefore report on the efficacy and safety of gastric UEMR
Diagnosis of chronic pancreatitis (CP) by shear wave elastography (SWE) of the pancreas. A prospective, single-center, observational study
Authors: Y. Dominguez-Novoa, J. E. Dominguez-Munoz, P. Miguez-Sanchez, D. De La Iglesia-Garcia, J. Lariño-Noia, J. Iglesias-Garcia
Journal: Endoscopy (2024)

Aims Advanced imaging techniques associated with EUS, such as strain elastography (SE), have proven to be useful in the diagnosis of CP. Recently, the development of SWE has opened a new alternative for the evaluation of pancreatic fibrosis. Our study aimed to evaluate the accuracy of SWE for the evaluation of patients with clinical suspicion of CP.
Factors affecting the diagnostic accuracy of EUS-FNA for pancreatic and peripancreatic lesions: a single-center experience
Authors: I. S. Papanikolaou, A. Stamou, E. Koukoulioti, C. Kapizioni, E. Rizos, A. Chatzidakis, E. Karatza, A. Anagnostou, A. Politi, K. Triantafyllou, A. Vezakis
Journal: Endoscopy (2024)

Aims Endoscopic-ultrasound fine-needle-aspiration (EUS-FNA) has become the standard of care for the diagnosis of pancreatic and peripancreatic tumors, and several factors are associated with its diagnostic accuracy. The aim of this study is to evaluate factors that are associated with the diagnostic accuracy of EUS-FNA in our center.
“Clip and line&amp;quot; technique for a mucosal defect closure
Authors: G. Cuccia, M. F. Chiappetta, T. Schepis, L. E. Del Vecchio, G. Costamagna, C. Spada, F. Barbaro
Journal: Endoscopy (2024)

Abstract Text During gastric submucosal dissection (ESD) of the anterior wall side, a perforation of the muscle layer (13-15 mm) with exposure of the serosa was found. Among different techniques, the "clip and line" technique was chosen, with the placement of four 11-mm endoclips. For a single episode of melena on the following day, the patient underwent further endoscopic examination. Although in the presence of a bleeding source, no further perforation was found. No long-term complications in subsequent endoscopic controls at 3 and 9 months. The "clip and line" technique could play a significant role in endoscopic procedures complicated by perforation, being a widely available and easy-to-approach method.
Validation and comparison of the CHAMPS score and other scores for nonvariceal upper gastrointestinal bleeding patients : A retrospective study
Authors: H. S. Moon
Journal: Endoscopy (2024)

Aims Various scoring systems for predicting the outcomes such as in-hospital mortality, radiological or surgical intervention, and re-bleeding have been developed for NVUGIB (Nonvariceal upper gastrointestinal bleeding) patients. Recently, a new prediction score, the CHAMPS score, has been developed to evaluate in-hospital mortality for NVUGIB patients who underwent hemostasis therapy. Since the CHAMPS score has only been validated and applied for Japanese patients, we validated the CHAMPS score and compared with other scores to evaluate the usefulness of this new scoring system in Korean patients.
EUS-GE: initial single center experience
Authors: A. Hujova, P. Macinga, J. Jarosova, J. Spicak, T. Hucl
Journal: Endoscopy (2024)

Aims Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) using a lumen-apposing metal stent (LAMS) is a novel endoscopic technique used to treat gastric outlet obstruction mostly caused by malignant disease such as pancreatic, gastric or biliary cancer. It is a technically challenging procedure with a high-risk of complications especially when performed by an endoscopist with limited experience.
A rare case of melena: Ampullary Hemangioma
Authors: J. Ghaith, A. A. Alkhatib, P. Joshi, E. Alessa
Journal: Endoscopy (2024)

Abstract Text A 64-years old female patient presented to the emergency department with melena and a drop in hemoglobin to 64mg/dl. After resuscitation, a gastroscopy was performed revealing a smooth atypical hemorrhagic mass protruding from the ampulla. Biopsies were obtained but were non-diagnostic. Due to the ongoing melena and lack of pathological diagnosis, the option of surgical biopsy and ampullectomy was offered and was preferred by the family. Computed tomography was performed and confirmed a 3.5 cm non-metastatic ampullary mass. The patient underwent un-eventful surgical ampullectomy. The final pathology was confirmatory for ampullary hemangioma. Ampullary Hemangioma are rare benign vascular tumor and can present with melena. Endoscopic hemostasis is challenging in those rare conditions and usually requires surgical resection.
The Double-Edged Sword of YouTube: Impact on Colon Cancer Screening Knowledge
Authors: R. M. Ram mohan, M. Joy, S. G. Magam, D. Natt, S. R. Magam, L. Pannikodu, J. Desai, P. Mustacchia
Journal: Endoscopy (2024)

Aims This research aims to scrutinize the content and quality of Colon Cancer screening awareness videos on YouTube, a platform widely utilized for health information. Despite boasting over a billion users, the absence of an editorial process on YouTube doesn't guarantee reliable content. The study finds that patient information is often substandard, potentially resulting in misinformation. This is especially concerning for crucial topics like Colon Cancer screening, as misleading information can distort users' perception and understanding of their health conditions.
Visual impression of biliary anastomotic strictures with per-oral cholangioscopy predicts therapeutic outcome in liver transplant recipients
Authors: A. Bofill, L. Calixto, O. Bassegoda, A. Fernandez-Simon, H. Cordova, O. Sendino, A. Cardenas
Journal: Endoscopy (2024)

Aims Biliary anastomotic strictures (BAS) after liver transplantation (LT) are the most common biliary adverse events in LT recipients. They are mainly managed with endoscopic retrograde cholangiopancreatography (ERCP) [1]. A prior pilot study from our group showed that per-oral cholangioscopy (POCS) identifies two distinct visual stricture patterns: type A (scarring) and type B (erythema with sloughing and/or ulceration) [2]. This study analyzed these two stricture patterns and compared treatment outcomes.
Diagnostic Accuracy of Different Cholangioscopy-Guided Biopsy Techniques for the Diagnosis of Indeterminate Biliary Duct Strictures
Authors: D. M. de Jong, P.J. F. De Jonge, P.M. C. Stassen, P. Karagyozov, J. J. Vila, I. Fernandez-Urien, M. W. James, S. Vasan Venkatachalapathy, K. Oppong, A. Anderloni, A. Repici, R. Gabbiadini, D. Joshi, M. Ellrichmann, M. L. Kylänpää, M. Udd, F. Van Der Heide, P. Hindryckx, G. Corbett, K. Basiliya, V. Cennamo, S. Landi, S. Phillpotts, G. Webster, M. J. Bruno
Journal: Endoscopy (2024)

Aims Indeterminate biliary duct strictures (IBDS) are a difficult diagnostic challenge. Digital single operator cholangioscopy (d-SOC) has improved diagnostic yield by the ability to obtain targeted intra-ductal biopsies by direct mucosal visualization. However, the optimal biopsy technique remains unclear. The aim of this study was to compare the diagnostic yield of d-SOC guided single standard biopsies to those obtained via bite-on-bite-biopsy (BBB) technique in patients with IBDS.
Retrograde Gastroesophageal Intussusception (with Video)
Authors: F. Shibli, A. Zoabi, H. Awadie, S. Shamah
Journal: Endoscopy (2024)

Abstract Text Retrograde gastroesophageal intussusception is a part of prolapse gastropathy syndrome (PGS) and is an invagination of part of the gastric mucosa into the lower esophagus. This results in partial or complete esophagogastric junction outlet obstruction. PGS is rare, with a reported incidence of 0.4-2.4%. The exact mechanism underlying PGS is unclear, although various factors have been proposed including relaxation of the gastroesophageal junction (GEJ), gastric mucosal redundancy, retrograde gastric peristalsis. Our case illustrates a rare presentation of PGS involving entrapment of the gastric fundus in a pseudodiverticulum obstructing the GEJ. Though surgery was prohibitively risky due to comorbidities, endoscopic gastropexy serves as a good treatment option.
Efficacy of Pre-oxygenation and High-Flow Nasal Oxygen during ERCP in High-risk patients with hypoxemia: A Randomized Controlled Trial
Authors: Y. Myung
Journal: Endoscopy (2024)

Aims Endoscopic retrograde cholangiopancreatography (ERCP), a procedure requiring deep sedation, poses an elevated risk of hypoxemia, particularly in high-risk patients. Pre-oxygenation and high-flow nasal oxygen (HFNO) have demonstrated effectiveness in improving oxygenation.
Single-Center Experience Of Managment Of Perforation After Endoscopical Submucosal Dissection (Esd) Using Over-The-Scope Clip
Authors: G. Leonardi, B. Toro, F. Bronzini, F. Rettura, M. R. Falcone, C. Sterpi, M. Blois, R. Manta
Journal: Endoscopy (2024)

Aims BACKGROUND AND AIMS: The Endoscopical Submucosal Dissection (ESD) is an advanced resection technique for removing "en bloc" gastrointestinal (GI) lesions, bigger than 20 mm and with macroscopic features of no deep infiltration (limited to the submucosal). It is a complex procedure and, therefore, with risk of complications (early and/or delayed), first of all bleeding, then perforation. Our aim is to confirm the pivotal role of Over-The-Scope Clip for menagement of perforation occurred during the ESD.
Beyond expectations: Tapeworm-related upper gastrointestinal bleeding in excluded duodenum
Authors: M. Martins, C. Hélder, M. Guilherme
Journal: Endoscopy (2024)

Abstract Text A 50-year-old female patient, one year post Roux-en-Y gastric bypass surgery, was hospitalized for persistent melena. After negative upper and lower endoscopies, capsule endoscopy revealed hematic residues in proximal jejunum. Initially suspected at Roux-en-Y anastomosis, subsequent double-balloon enteroscopy ruled out active bleeding in gastric pouch and jejunal limb, including surgical anastomosis. A translucent filament, resembling a tapeworm's neck, was observed in alimentary limb extending from Y-roux anastomosis. Retrograde intubation of afferent limb confirmed its presence, reaching proximally into duodenum, where oozing active bleeding ulcer was identified. Due to absence of visible vessel, Hemospray was used and no mechanical treatment was applied. We present a case of upper gastrointestinal (GI) bleeding from excluded duodenum associated with a tapeworm infection.
Clinical outcomes of endoscopic treatment in acute cholangitis: comparison between Tokyo guidelines 2018 and ASGE 2021
Authors: M. De Ruvo, S. Grillo, M. Vicentini, V. G. Mirante, P. Cecinato, F. Bassi, E. Savarino, R. Sassatelli
Journal: Endoscopy (2024)

Aims The optimal endoscopic approach during acute cholangitis (AC) remains controversial. There is currently no agreement on the timing of biliary drainage, nor on the endoscopic technique: Tokyo guidelines (TG18) recommend to perform only biliary drainage in several cases, because of the risk of bleeding after sphincterotomy (EST) in this setting; on the other hand ASGE guideline suggests to remove the cause of cholangitis (i.e. biliary stones) too in a single procedure (combined strategy), regardless of degree of severity. This study describes a case series of AC and compares findings with the reference guidelines.
Comparative Evaluation of Endoscopic Anti-reflux Mucosectomy and Stretta Radiofrequency Ablation in the Management of Gastroesophageal Reflux Disease: Insights from a Retrospective Multi-Center Cohort Study
Authors: A. Y. Lee, J. Y. Seo, S. H. Kim, J. Y. Cho
Journal: Endoscopy (2024)

Aims Treatment options for Gastroesophageal reflux disease (GERD) that is unresponsive to proton pump inhibitors (PPIs) are still not well-established. This study includes over 400 individuals who underwent anti-reflux mucosectomy (ARMS) or Stretta radiofrequency (SRF) for the treatment of intractable GERD and compares these two therapeutic methods for intractable GERD.
Traditional Biomarkers And Pancreatic Cancer: There Is Still A Role In The Molecular Era?
Authors: M. G. Demarzo, M. Mossa, C. Marrone, L. Assandri, F. Mazza, M. C. Parodi
Journal: Endoscopy (2024)

Aims As known, the overall survival and the prognosis of patients with pancreatic cancer (PC) remain poor as most of the cases are diagnosed at advanced stages due to the lack of specific symptoms and biomarkers.Serum carbohydrate antigen 19-9 (Ca19-9) is used to monitor response to treatment and identify patients with poor prognosis, but its value as a screening or early diagnostic tool remains controversial. New blood-based biomarkers such as cell-free DNA, exosomes, and circulating tumor cells are currently being investigated for monitoring response to treatment but they are far from be included in clinical practice.The aim of our study is to evaluate the role of traditional serum biomarkers in the management of PC patients staged by both Computed tomography (CT) and Endoscopic ultrasound (EUS).
Iron Sulfate-related gastric lesions
Authors: M. De Siena, T. Schepis, M. F. Chiappetta, L. E. Del Vecchio, V. Bove, I. Boskoski, C. Spada
Journal: Endoscopy (2024)

Abstract Text A 15-year-old woman presented with severe epigastric pain and dark grey vomiting after the ingestion of 60 tablets of iron sulfate (329,7 mg/single tab). Blood exams were unremarkable unless for increased iron levels (550 µg /dl). At the upper gastrointestinal endoscopy the gastric cavity appeared coated by jelly mucous secretions mixed with the dissolved tablet residues; diffuse mucosal oedema, multiple erosions, and spot bleedings. Residual tablets were gently removed with a Roth-Net basket to prevent dissolution and further absorption. Acute iron poisoning should be consider in emergency departments as a mechanism of injury in suicide attempts [1]. Early endoscopy is essential in this setting to assess the damage [2] [3].
Quality of Colonic Preparations in the Real-World: Comparing of three agents, results of a large cohort
Authors: N. Abu-Freha, R. Guterman, R. Elhayany, A. Fich, Y. Avraham
Journal: Endoscopy (2024)

Aims Different bowel preparation formulas are used in colonic preparation before colonoscopy. The study aimed to investigate colonoscopy quality in three different colonoscopy preparation agents.
Evaluation of elderly patients admited for hospitalization due to upper gastrointestinal bleeding: a prospective study
Authors: F. J. Sánchez Roncero, C. Bógalo Romero, C. Espuche Jiménez, A. Gómez Gómez, L. Madrigal Bayonas, J. Egea Valenzuela, F. Alberca De Las Parras
Journal: Endoscopy (2024)

Aims Mortality related to upper gastrointestinal bleeding (UGB) is up to 5% in some studies, especially in elderly patients. The aim of this study is to evaluate personal history, endoscopic findings and evolution in elderly patients as a base to future studies.
Anastomotic dehiscence after endoscopic mucosal resection
Authors: M. Pedro, C. Gomes, P. Ana, M. M. Estevinho, J. Correia, T. Freitas
Journal: Endoscopy (2024)

Abstract Text A 75-year-old man, with a history of colorectal anastomosis secondary to rectal cancer surgery was referred for endoscopic resection of a 9 cm LST-G (Is+IIa) located at 1 cm of the anal margin and occupying 1/3 of the bowel lumen. Mucosal and vessel pattern was mostly regular (JNET 2A), with depressed area over the anastomosis with biopsies showing high-grade dysplasia. Due to dificulty with the elevation of the lesion we proceeded with pEMR and STSC in detriment of ESD. One month later, we diagnosed an anastomotic dehiscence measuring 20x75mm. The decision was to perform a protective colostomy and endoluminal vacuum therapy and with 9 sessions in 1 month, the cavity downsized to 10x20mm and completely healed in 2 months Histology revealed carcinoma in situ. The patient is waiting for a follow up colonoscopy.
Safety of cholangio-pancreatoscopy: a single-center cohort study
Authors: R. Valente, M. Al-Jubouri, U. Arnelo
Journal: Endoscopy (2024)

Aims Indeterminate biliary strictures are challenging to diagnose through traditional cross-sectional imaging. Single operator peroral cholangioscopy (SOPC) has improved the diagnostic yield allowing direct visualization and targeted biopsies, but previous studies have reported a potential higher risk of complications. However, most published series include potential sources of heterogeneity, such as the involvement of multiple operators, the inclusion of both cholangioscopy and pancreatoscopy, and a blending of different potential indication for the ERCP. The assessment of safety in SOPC still remain a poorly investigated issue in hepatobiliary endoscopy. The aim of the study is to assess the rate complications in patients undergone SOPC at a tertiary reference center.
An old tool for a new portal hypertension entity: innovative Application of tips in addressing complications of psvd and enabling Curative intervention for high-grade dysplastic sub-cardial lesion: a Case report
Authors: F. Barbaro, S. S. De Lucia, L. Galasso, F. Termite, T. Schepis, M. F. Chiappetta, A. Contegiacomo, F. Santopaolo, B. E. Annicchiarico, A. Gasbarrini, C. Spada
Journal: Endoscopy (2024)

Abstract Text A 78-year-old male diagnosed with oxaliplatin-associated PSVD presented at our unit for variceal bleeding. Endoscopic band ligation was employed fortreatment. Initial assessment showed a portal pressure gradient (PPG) of 21 mmHg. Subsequentgastroscopy revealed recurrent high-risk gastro-esophageal varices (GOV) and an adjacent mucosallesion histologically confirmed as focal high-grade dysplasia. In consideration of very high risk of endoscopic submucosal dissection (ESD)-related bleeding, a TIPS was positioned between the righ hepatic vein andintrahepatic branch of the right portal vein. Post-procedural PPG was 5 mmHg. TIPS was well-tolerated, with only two episodes of grade I hepatic encephalopathy reported. Two months later, nosigns of PH were endoscopically detected and the ESD was successfully performed, resulting in thecomplete removal of the sub-cardial lesion without complications.