tbuckley/cabot-search huggingface dataset:
Accuracy and Efficacy of the Endoscopic Ultrasound (EUS) in diagnosing Focal Liver Lesion (FLL), obtaining Liver sampling and Liver Abscess drainage; Meta-Analysis and Systematic Review
Authors: E. Gadour, A. Awad, Z. Hassan, K. Shrwani, B. Miutescu, H. H. Okasha
Journal: Endoscopy (2024)

Aims Recently, there has been a surge in the clinical utilization of endoscopic ultrasound (EUS) in hepatology [1]. These applications range from diagnosis to treatment of various liver diseases [2]. Therefore, the current systematic review has summarized the evidence on the diagnostic and therapeutic roles of EUS in liver diseases.
Randomized controlled trial of a cloud-based artificial intelligence (AI) computer-aided diagnosis (CADx) system in non-expert endoscopists (CADDIE)
Authors: R. Kader, P. Bassett, Y. Kabir, S. Cheung, L. Macabodbod, A. Jayanthi, I. T. Caddie, M. Chand, L. Lovat
Journal: Endoscopy (2024)

Aims Non-expert endoscopists' optical diagnosis (OD) of polyps falls short of 'resect and discard' and 'diagnose and leave' thresholds. Previous CADx studies are limited to locally deployed hardware AI systems and are mainly evaluated in expert endoscopists. CADDIE is a cloud-based CADx system that receives the live image stream from the endoscopy screen via the hospital's internet network, where the AI algorithm processes the images and outputs its diagnosis (adenoma, non-adenoma or uncertain) on the endoscopy screen. We aimed to assess the performance of the real-time cloud-based CADDIE system when colonoscopy is undertaken by non-expert endoscopists (adenoma detection rate below 30%).
A pre-training model for intestinal metaplasia recognition in the gastric corpus: preliminary data analysis
Authors: I. Ligato, G. De Magistris, E. Dilaghi, G. Cozza, A. Ciardiello, C. Voena, S. Giagu, B. Annibale, C. Napoli, G. Esposito
Journal: Endoscopy (2024)

Aims Gastric cancer (GC) is a significant healthcare concern and the recognition of high-risk patients is crucial [1]. The common mechanism for the progression of GC is the Correa cascade, which outlines a multi-step progression from chronic gastritis through atrophic gastritis, intestinal metaplasia (IM), dysplasia and finally GC. The detection of IM in the stomach is not always easy, especially when it is focal. While electronic chromoendoscopy has demonstrated high diagnostic accuracy for IM [2], its limited availability, and the variable expertise of endoscopists pose challenges. Additionally, the potential of artificial intelligence (AI) to aid endoscopists has obtained significant attention. This study aims to develop a deep-learning system to assist in IM diagnosis based on endoscopic image patches.
Faecal immunochemical test to detect colorectal neoplasia in Lynch syndrome – a prospective multicentre study
Authors: E. van Liere, N. De Boer, M. Van Leerdam, E. Dekker, M. Jacobs, J. J. Koornstra, J. Kuijvenhoven, M. Lemmens, G. Meijer, M. Spaander, B. Carvalho, D. Ramsoekh
Journal: Endoscopy (2024)

Aims Colonoscopy surveillance for Lynch syndrome is burdensome and post-colonoscopy colorectal cancers (CRCs) still occur. The non-invasive faecal immunochemical test (FIT) might guide optimal colonoscopy intervals.
Cholangiopancreatoscopy SpyGlass-DS experience in a Spanish tertiary hospital
Authors: C. Amiama Roig, E. Martin-Arranz, R. Fernandez Martos, C. Amor Costa, I. Gonzalez diaz, M. D. Martin-Arranz
Journal: Endoscopy (2024)

Aims Cholangiopancreatoscopy has become an essential tool in ERCP. Our aim is to evaluate its efficacy and safety using the SpyGlass-DS device in a Spanish tertiary center.
Combined biliary obstruction and gastric outlet obstruction (GOO) management: comparison of various strategies of biliary stenting and duodenal derivation in terms of reintervention risk: expert single center experience
Authors: J. M. Gonzalez, I. Boutellier, M. Gasmi, M. Barthet
Journal: Endoscopy (2024)

Aims Combined biliary obstruction and gastric outlet obstruction (GOO) is a therapeutic challenge in endoscopy, especially due to the risk of biliary obstruction after drainage, hindering the continuation of chemotherapy in fragile patients. Moreover, the development of EUS-guided biliary drainage and gastroenterostomies multiplied the therapeutic strategies. Only one study to date suggested that EUS-choledocoduodenostomy has the higher risk of stent obstruction. We evaluated different strategies for therapeutic EUS compared to ERCP in an expert center mastering all these techniques.
Capsule endoscopy for small-bowel surveillance in Lynch syndrome patients: a 20-year cohort experience
Authors: P. Cortegoso Valdivia, D. Pitoni, G. Mistretta, L. Laghi, M. Pennazio
Journal: Endoscopy (2024)

Aims Lynch syndrome (LS) is an autosomal dominant hereditary disease caused by germline mutations in the DNA mismatch repair (path_MMR) genes. LS carriers harbor a high risk of developing early-onset gastrointestinal (GI) and extra-GI malignancies, including small-bowel (SB) cancer for which a consensus recommendation for screening is lacking [1], as recent evidence failed to demonstrate a clear benefit of SB cancer screening with capsule endoscopy (CE) [2]. Accordingly, our study aims to assess the effectiveness of SB cancer surveillance with CE in a large cohort of LS patients.
Human-Computer Interaction: Impact of Artificial Intelligence on the diagnostic confidence of endoscopists assessing videos of Barrett’s esophagus
Authors: D. A. Roser, M. Meinikheim, R. Mendel, C. Palm, A. Probst, A. Muzalyova, M. W. Scheppach, S. Nagl, E. Schnoy, C. Römmele, D. Schulz, J. Schlottmann, F. Prinz, D. Rauber, T. Rückert, T. Matsumura, G. Fernandez-Esparrach, N. Parsa, M. Byrne, H. Messmann, A. Ebigbo
Journal: Endoscopy (2024)

Aims Human-computer interactions (HCI) may have a relevant impact on the performance of Artificial Intelligence (AI). Studies show that although endoscopists assessing Barrett's esophagus (BE) with AI improve their performance significantly, they do not achieve the level of the stand-alone performance of AI. One aspect of HCI is the impact of AI on the degree of certainty and confidence displayed by the endoscopist. Indirectly, diagnostic confidence when using AI may be linked to trust and acceptance of AI. In a BE video study, we aimed to understand the impact of AI on the diagnostic confidence of endoscopists and the possible correlation with diagnostic performance.
Long-term results of endoscopic pyloromyotomy: follow-up of a randomized, sham-controlled trial (GREG)
Authors: K. Hugova, D. Simkova, J. Mares, R. Hustak, S. Amin, D. Pohl, J. Spicak, J. Martinek
Journal: Endoscopy (2024)

Aims We previously reported 6 months results of a prospective randomized sham-controlled trial comparing endoscopic pyloromyotomy (G-POEM) with a sham procedure in patients with gastroparesis (GREG, 1). G-POEM was superior to sham in terms of symptoms improvement and gastric emptying rate. Moreover, cross-over G-POEM, which was performed after a sham procedure was effective in 75% of patients. All patients have been prospectively followed according to an original protocol. Here, we report the long-term results. Unblinding of patients occurred 6 months after the originally allocated procedure (G-POEM or sham).
Submucosal-bulge sign as an endoscopic predictor of a colonic mucinous adenocarcinoma
Authors: S. Wang, J. Santiago Garcia, A. M. Dotor De Lama, D. De Frutos Rosa, C. Fernandez Carrillo, F. Valentin Gomez, A. Herreros De Tejada Echanojauregui
Journal: Endoscopy (2024)

Abstract Text Colonic mucinous adenocarcinomas (CMAC) are commonly diagnosed at an advanced stage, though, their management and prognosis still remain controversial. We report the case of a 59-years-old man who underwent a screening colonoscopy. A 18mm sessile lesion was found in the sigmoid colon showing a regular surface and vascular pattern. This lesion presented a remarkable submucosal cushion, although no prior submucosal injection was done. En-bloc underwater endoscopic mucosal resection was performed, and a large mucous lake was found along the resection margin. Histological examination revealed a tubulovillous adenoma with a buried pT1 mucinous adenocarcinoma infiltrating the vertical margin. In conclusion, the CMAC might appear with a submucosal-bulge aspect, which was not previously described. Identifying this endoscopic sign may determine its management. [1] [2]
Enteroscopy-assisted ERCP versus EUS-antegrade intervention for Stones and/or Strictures in patients with Roux-en-Y Hepaticojejunostomy: A Tertiary Center Comparison
Authors: M. Bronswijk, A. Van Oosterwyck, T. Ogura, S. Van der Merwe
Journal: Endoscopy (2024)

Aims Although PTC and enteroscopy-assisted ERCP (e-ERCP) are often preferred for bile duct access in patients with hepaticojejunostomy (HJ) and Roux-en-Y reconstruction, these approaches are plagued by either relatively high morbidity or suboptimal effectiveness respectively. EUS-guided antegrade intervention (EUS-AI) of HJ strictures and/or stones has been suggested as a safe and effective alternative by creating an easily re-accessible portal to the biliary tree, although limited comparative data are available. Our aim is to compare EUS-AI with e-ERCP for HJ strictures and/or stones.
Over-the-scope-clips reduce rebleeding and mortality in upper GI bleeding: Results of a large propensity score matched cohort study
Authors: A. Vella Baldacchino, K. Mushtaq, P. Boger, P. Patel, I. Rahman
Journal: Endoscopy (2024)

Aims Non-variceal upper gastrointestinal bleeding (UGIB) remains a common medical emergency with a high mortality rate. Advances in endoscopic therapies have the potential to improve patient outcomes. This study aimed to determine whether use of over-the-scope clips in UGIB has an impact on rebleeding and mortality rates compared to conventional endoscopic treatment.
Impact of immersive virtual reality during outpatient sedation-free colonoscopy: A randomized prospective controlled study
Authors: M. Ayari, S. Riahi, I. Abdelaali, H. Douggui, T. Jomni
Journal: Endoscopy (2024)

Aims The aim of this study was to evaluate the impact of intraprocedural immersive virtual reality (VR) combining visual and auditory distraction in the improvement of the tolerance and the progress during unsedated colonoscopy.
Endoscopic biliary drainage in patient with Surgically-alTeREd anaTomy: the STREeT multicenter Italian study
Authors: A. Mauro, G. Vanella, V. G. Mirante, A. Fugazza, M. Spadaccini, E. Forti, C. Binda, R. Di Mitri, D. Berretti, H. Bertani, P. Cantù, L. De Luca, F. Desideri, R. Grassia, R. Leone, A. Lisotti, M. Manno, S. Mazza, A. Mussetto, I. M. Parisi, A. Parodi, G. Venezia, V. Ferretti, G. Gambini, P. Arcidiacono, M. Mutignani, R. Sassatelli, I. Tarantino, C. Fabbri, A. Anderloni
Journal: Endoscopy (2024)

Aims Endoscopic biliary drainage (BD) in patients with altered anatomy is a challenging scenario, reducing the chance of clinical success compared to standard anatomy. The choice between different BD approaches is still not standardized and relies on local availability and expertise. Aim of this study was to explore the approach to BD in patients with altered anatomy in different Italian centers, including the number of attempts.
Antegrade ERCP via EUS-guided LAMS-jejunoduodenostomy in Roux-en-Y subtotal gastrectomy (RYSG) facilitated by mapping EUS-pancreatography
Authors: S. J. Fernández Prada, I. Ruiz Nuñez, M. Cobreros del Caz, R. Sánchez-Ocaña, C. De La Serna Higuera, M. Perez-Miranda
Journal: Endoscopy (2024)

Abstract Text Introduction: EUS imaging of the duodenum during transenteric ERCP is challenging after RYSG.
Single-session EUS-directed Transgastric ERCP with a Dedicated Over-the-scope Fixation Device: A Feasibility Study
Authors: M. Bronswijk, S. Van der Merwe
Journal: Endoscopy (2024)

Aims EUS-directed Transgastric ERCP (EDGE) has been proposed as a more effective alternative to enteroscopy-assisted ERCP for patients with Roux-en-Y gastric bypass anatomy, overcoming the invasiveness of laparoscopy-assisted ERCP. Postponing through-the-LAMS ERCP for 1-2 weeks and employing stent fixation techniques have been suggested to reduce the risk of stent migration. Our aim is to investigate the feasibility of a single-session EDGE using a dedicated over-the-scope fixation device.
Significant Missed Polyps in Bowel Cancer Screening Programme Patients in the Cheshire Region of the UK
Authors: A. Golash, K. Yoong, A. Murray, C. Chesters, L. Findler, R. saravanan
Journal: Endoscopy (2024)

Aims Colorectal cancer (CRC) is the second-biggest cause of cancer deaths in the UK. Currently, bowel cancer screening is offered to everyone aged 60-75 years via a Faecal Immunochemical Test (FIT). Those receiving an abnormal result are offered a colonoscopy. Pre-malignant polyps are responsible for the majority of CRCs. Patients at highest risk were those with≥2 polyps and at least one≥10mm of any grade dysplasia. The effectiveness of colonoscopies can, however, often be challenged by the occurrence of missed polyps. This retrospective review looks at the incidence of polyps≥10mm relative to the overall number of missed polyps in Bowel Cancer Screening Patients (BCSP) in the Cheshire region of the UK.
Medium-term oncological outcomes following endoscopic full-thickness resection for T1 colorectal cancer: results from the Dutch prospective colorectal eFTR registry
Authors: S. C. Albers, L. W. Zwager, B. Van Der Spek, R. M. Schreuder, L. Perk, B. Weusten, J. Boonstra, H. Van Der Sluis, M. Schwartz, M. Vlug, C. Wientjes, F. Rando Munoz, W. Nagengast, F. Bekkering, R. Ten Hove, J. Terhaar Sive Droste, M. Houben, T. Seerden, T. De Wijkerslooth, E. Gielisse, A. Farina Sarasqueta, P. Fockens, E. Dekker, B. A. Bastiaansen
Journal: Endoscopy (2024)

Aims Endoscopic full thickness resection (eFTR) is increasingly used as a minimally invasive diagnostic and potential therapeutic approach for smaller (≤2cm) T1 colorectal cancer (CRC). EFTR enables transmural resection, providing optimal histological risk assessment and complete (R0) resection, even in deep submucosal invasive cancer (D-SMIC). However, follow-up (FU) outcomes have not yet been described. This study aims to describe the medium-term oncological outcomes of eFTR for T1CRC.
Cost-utility analysis of using the haemostatic powder TC-325 as a first-line treatment for malignant upper gastrointestinal bleeds in the United Kingdom
Authors: D. Cooper, N. Benjamin, N. Hawkes, S. Hebbar, A. Telese, J. Morris, R. Haidry, A. Barkun
Journal: Endoscopy (2024)

Aims Haemostatic powder TC-325 is a valuable option for the management of malignant upper gastrointestinal bleeding (MUGIB). Randomised control trial (RCT) data has shown it results in greater immediate haemostasis and lower 30-day rebleeding rates when compared to standard endoscopic therapy (SET). Initial purchase cost for TC-325 can be higher compared with standard endoscopic treatments. We sought to determine if the use of haemostatic powder TC-325 would be cost-effective as a first-line option for MUGIB compared with SET in the United Kingdom.
“Smart glasses” for first time gastrostomy tube replacement at home by a specialist endoscopy nurse: initial experience
Authors: A. Parrella, G. F. Bonura, S. Deiana, T. Gabbani, P. Soriani, A. Franchini, E. Algeri, P. Biancheri, M. Manno
Journal: Endoscopy (2024)

Aims Advances in medical technology are rapidly changing how healthcare professionals perform their job. "Smart glasses" (Rods and Cones, Amsterdam, The Netherlands) are a new medical device that facilitates remote assistance in healthcare setting. Smart glasses create a GDPR- and HIPAA-compliant connection between a clinician or a nurse and a remotely-located expert, who is able to watch the procedure in real-time and full high definition (HD), and to provide interactive assistance. Smart glasses have been successfully employed in surgery and anesthesiology and, recently, we introduced them in our routine endoscopic clinical practice. Since travels to hospital may be challenging for frail patients, we aimed to evaluate the use of smart glasses as a support technology for specialist endoscopy nurses performing first time percutaneous endoscopic gastrostomy (PEG) tube replacement at patient's home.
Gastric endoscopic submucosal dissection: can we trust the initial forceps biopsy?
Authors: A. I. Ferreira, T. Lima Capela, V. Macedo Silva, S. Xavier, P. Boal Carvalho, J. Magalhães, J. Cotter
Journal: Endoscopy (2024)

Aims Evaluate factors associated with upstaging and downstaging pathological results in gastric endoscopic submucosal dissection (ESD) specimens.
Feasibility of Mucosal Defect Closure Using Clip with Line Pulley Securing (CLiPS) Technique after Gastric Endoscopic Submucosal Dissection
Authors: T. Kimura, Y. Minato, S. Banjoya, T. Iida, S. Nagae, K. Furuta, Y. Ito, H. Yamazaki, N. Takeuchi, S. Takayanagi, Y. Kimoto, Y. Kano, T. Sakuno, K. Ono, K. Ohata
Journal: Endoscopy (2024)

Aims In recent years, there have been scattered reports on mucosal defect closure aimed at preventing serious complications such as delayed bleeding and perforation in gastric ESD. However, there is currently no established technique. To address these issues, we developed the Clip with Line Pulley Securing (CLiPS) technique, a simple and cost-effective closure method using widely available materials.
Feasibility and Effectiveness Comparative Analysis of Standard Endoscopic Ultrasound vs Novel Adaptable Endoscopic Ultrasound Probe Evaluation: A Multi-Institutional Prospective Study
Authors: C. Robles-Medranda, D. Cunto, M. Arevalo-Mora, M. Puga-Tejada, M. Egas-Izquierdo, J. Baquerizo-Burgos, J. Alcivar-Vasquez, R. Del Valle, M. J. Metah, A. V. Sahai, B. S. Lim, M. A. Paez, H. Pitanga-Lukashok
Journal: Endoscopy (2024)

Aims EndoSound Vision System (EndoSound, Oregon, USA) is a new EUS (N-EUS) portable probe that fastens onto a standard gastroscope. We aim to determine the feasibility and effectiveness of N-EUS in terms of anatomical structures appropriate identification in comparison with conventional-EUS.
Strict endoscopic follow-up after endoscopic resection (R0) of high-risk T1 adenocarcinoma in Barrett&amp;apos;s esophagus seems feasible: Preliminary results of a prospective, international, multicenter cohort study (PREFER)
Authors: M. W. Chan, E. Nieuwenhuis, M. Jansen, W. B. Nagengast, J. Westerhof, H. Neuhaus, T. Beyna, A. Koch, M. Spaander, M. J. Bourke, R. Bisschops, G. De Hertogh, B. Weusten, A. Alkhalaf, O. Pech, S. Seewald, R. Haidry, D. De Wulf, C. Schlag, E. J. Schoon, M.H.M. G. Houben, H. Messmann, P. Dewint, J. O. Fernández-Sordo, S. Meijer, J. Bergman, R. Pouw
Journal: Endoscopy (2024)

Aims Optimal management following radical endoscopic resection (R0 ER) of T1 esophageal adenocarcinoma (EAC) is still a matter of debate due to conflicting reports on the risk for lymph node metastases (LNM). In case of histological risk factors for LNM, i.e. submucosal invasion, a/o poor differentiation, a/o lympho-vascular invasion (LVI), additional treatment with esophagectomy is often still recommended. In this prospective international multicenter cohort study (NCT03222635), we aim to evaluate the safety of a strict endoscopic follow-up (FU) strategy following R0 ER for T1b and high-risk T1a EAC.
Endoscopic full-thickness resection of duodenal neuroendocrine tumors using the Full-Thickness Resection Device (FTRD): Results from a large, retrospective, multicenter study
Authors: A. Wannhoff, Z. Nabi, L.M. G. Moons, G. Haber, P. Ge, T. Dertmann, P. H. Deprez, C. Bouvette, J. Mueller, G. grande, M. F. Kaminski, J.J. W. Kim, A. Weich, P. Bauerfeind, J. George, M. Pioche, F. V. Mandarino, K. Kouladouros, G. Tribonias, P. Boger, B. Hayee, M. Bilal, S. C. Albers, P. Leclercq, G. Paspatis, M. Caselitz, A. Sharma, S. Arulprakash, M. Zachäus, S. Irani, M. Barret, J. Hoare, U. Denzer, G. Moog, A. Ebigbo, K. Caca
Journal: Endoscopy (2024)

Aims Duodenal neuroendocrine tumors (dNET) are rare tumors of the small intestine and are often found as an incidental finding of a subepithelial lesion during endoscopy. The Full-Thickness Resection Device (FTRD) enables endoscopic full-thickness resection of epithelial and subepithelial lesions. Endoscopic mucosa resection (EMR) has a low R0 resection rate for this indication, while endoscopic submucosal dissection (ESD) is associated with a higher rate of adverse events.
Abstract 9825: Stenotic Pulmonary Artery Reconstruction Using <i>in vivo</i> Tissue Engineered Vascular Grafts
Authors: Yoshinobu Maeda, Masaaki Yamagishi, Satoshi Asada, Hisayuki Hongu, Eijiro Yamashita, Hiroki Nakatsuji, Takashi Nagase, Rie Nakai, Keiichi Kanda, Tomoya Inoue, Masashi Yamanami, Hitoshi Yaku
Journal: Circulation (2021)

Introduction: We have applied in vivo tissue engineered vascular grafts (TEVGs) created in the patient's body for surgical reconstruction of the pulmonary artery (PA) as a substitute material for autologous pericardium. This study reports evaluations of PA reconstruction with in vivo TEVGs. Methods: Molds of in vivo TEVGs made of silicon tubes (outer diameter: 19Fr) were embedded into the subcutaneous spaces more than 6 months before the operation. Then, in vivo TEVGs created around the molds were harvested and used as patch materials to treat PA stenosis after the preparation period. Nine patients underwent mold embedding between July 2014 and February 2021. Two of the nine patients underwent mold re-embedding after harvesting the primary mold. Median age at mold embedding was 2.1 years (range, 1.2 to 5.0 years), median body weight was 10.2 kg (range, 7.3 to 15.4 kg), and median number of embedded molds per patient was 2 (range, 2 to 4). Results: The total number of molds embedded was 27, of which two were 35 mm long, nine were 40 mm long, four were 45 mm long, and 12 were 50 mm long. In vivo TEVGs were successfully harvested and autologously implanted for patch augmentation of stenotic PAs in six patients, and three patients are currently awaiting surgery. The median preparation period for creating in vivo TEVGs was 314 days (range, 180-1050 days). Median follow-up period after PA reconstruction was 16 months (range, 4 months to 6.1 years). Early mortality and late death did not occur. In addition, in vivo TEVG-related complications, including hemorrhage, aneurysmal change, degeneration and infection, were not observed. The mechanical properties were as follows: mean suture retention, 2.01 ± 0.26 N; and mean burst pressure, 2777 ± 246 mmHg. Conclusions: In vivo TEVGs are safe for use in PA reconstruction and might be a useful alternative material to autologous pericardium in multistage surgery for congenital heart disease with hypoplastic pulmonary arteries.
Safety of Duodenal Endoscopic Submucosal Dissection for Superficial Non-ampullary Duodenal Epithelial Tumor: A Single-center Study in the United States
Authors: M. Koseki, M. Nishimura, T. Nammour, S. Nagao, J. Beauvais, M. A. Schattner
Journal: Endoscopy (2024)

Aims Superficial non-ampullary duodenal epithelial tumors (SNADETs) are duodenal adenomas with malignant potential originating above the mucosal layer. Therefore, it is recommended that adenomas in the duodenum be resected in all cases. Currently, there are no guidelines in the U.S. addressing this; however, the ESGE recommends that all duodenal adenomas should be considered for endoscopic resection as progression to invasive carcinoma is highly likely. Endoscopic submucosal dissection (ESD) for SNADETs is associated with a high rate of en bloc resection. However, the technique for duodenal ESD remains challenging and is rarely performed in the U.S. due to the thin duodenal wall and unstable scope maneuverability. To date, most SNADETs are removed by either endoscopic mucosal resection (EMR) or surgery as the feasibility and safety for duodenal ESD procedure have not been proven in this country. We report a single-center retrospective analysis of the outcomes of duodenal ESD for SNADET in the U.S.