tbuckley/cabot-search huggingface dataset:
Early Dysglycemia Is Detectable Using Continuous Glucose Monitoring in Very Young Children at Risk of Type 1 Diabetes
Authors: Aveni Haynes, Alexandra Tully, Grant J. Smith, Megan A.S. Penno, Maria E. Craig, John M. Wentworth, Tony Huynh, Peter G. Colman, Georgia Soldatos, Amanda J. Anderson, Kelly J. McGorm, Helena Oakey, Jennifer J. Couper, Elizabeth A. Davis, Simon C. Barry, Maria E. Craig, Peter G. Colman, Jennifer J. Couper, Elizabeth A. Davis, Emma Hamilton-Williams, Leonard C. Harrison, Aveni Haynes, Tony Huynh, Ki Wook Kim, Grant Morahan, Helena Oakey, Megan A.S. Penno, William D. Rawlinson, Richard O. Sinnott, Georgia Soldatos, Rebecca L. Thomson, Jason Tye-Din, Peter J. Vuillermin, John M. Wentworth, Fergus Cameron, Andrew Day, Prudence Lopez, Amanda J. Anderson, Pat Ashwood, James D. Brown, William Hu, Dao Huynh, Kelly J. McGorm, Kelly Watson, Sarah Beresford, Debra Bezuidenhout, Susan Brandrick, Carlie Butterworth, Jacki Catteau, Helen Griffiths, Alison Gwiazdzinski, Candice Hall, Amanda Hulley, Lee Henneken, Renee Kludas, Ying Mateevici, Benjamin Ramoso, Alison Roberts, Alexandra Tully, Rosemary Wood, Sabrina Binkowski, Minh Bui, Abbey Gilbert, Dexing Huang, Ana Karceva, Brydie-Rose Mellor, Gaetano Naselli, Katrina Ngui, Trung Nguyen, Bina Patel, Vanessa Prajitno, Natalie Stone, Thao Tran, Sapphire Vaega, Emily Ward, Yan Xu, Cynthia Yau, Rachel Battersby, Bek Brittain, Charles Foster, Christopher Hope, Preston Leung, Kylie-Ann Mallitt, Alexandra Roth-Schulze, Tim Sadlon, Bree Tillett, Gregory Walker, Ying Wong, Enrique Zozaya-Valdes, Leanne Cavenett
Journal: Diabetes Care (2024)

Continuous glucose monitoring (CGM) can detect early dysglycemia in older children and adults with presymptomatic type 1 diabetes (T1D) and predict risk of progression to clinical onset. However, CGM data for very young children at greatest risk of disease progression are lacking. This study aimed to investigate the use of CGM data measured in children being longitudinally observed in the Australian Environmental Determinants of Islet Autoimmunity (ENDIA) study from birth to age 10 years.
NUAK1-Mediated Phosphorylation of NADK Mitigates ROS Accumulation to Promote Osimertinib Resistance in Non-Small Cell Lung Carcinoma
Authors: Wei Lin, Na Wang, Shihao Wu, Mingxin Diao, Quanfu Huang, Kuo Li, Peiyuan Mei, Xiaojun Wang, Yongde Liao, Yunchong Meng
Journal: Cancer Research (2024)

Abstract Osimertinib, a third generation epidermal growth factor receptor tyrosine kinase inhibitor, is approved as a first-line therapy in patients with advanced non–small cell lung carcinoma (NSCLC) with EGFR-activating mutations or the T790M resistance mutation. However, the efficacy of osimertinib is limited due to acquired resistance, highlighting the need to elucidate resistance mechanisms to facilitate the development of improved treatment strategies. Here, we screened for significantly upregulated genes encoding protein kinases in osimertinib-resistant NSCLC cells and identified NUAK1 as a pivotal regulator of osimertinib resistance. NUAK1 was highly expressed in osimertinib-resistant NSCLC and promoted the emergence of osimertinib resistance. Genetic or pharmacological blockade of NUAK1 restored the sensitivity of resistant NSCLC cells to osimertinib in vitro and in vivo. Mechanistically, NUAK1 directly interacted with and phosphorylated nicotinamide adenine dinucleotide kinase (NADK) at serine 64 (S64), which mitigated osimertinib-induced accumulation of reactive oxygen species (ROS) and contributed to the acquisition of osimertinib resistance in NSCLC. Furthermore, virtual drug screening identified T21195 as an inhibitor of NADK-S64 phosphorylation, and T21195 synergized with osimertinib to reverse acquired resistance by inducing ROS accumulation. Collectively, these findings highlight the role of the NUAK1-NADK axis in governing osimertinib resistance in NSCLC and indicate the potential of targeting this axis as a strategy for circumventing resistance. Significance: Phosphorylation of NADK by NUAK1 diminishes ROS accumulation and confers resistance to osimertinib, identifying NUAK1-NADK signaling as a potential therapeutic target for improving the response to EGFR inhibition in lung cancer.
Causal effect of video gaming on mental well-being in Japan 2020–2022
Authors: Hiroyuki Egami, Md. Shafiur Rahman, Tsuyoshi Yamamoto, Chihiro Egami, Takahisa Wakabayashi
Journal: Nature Human Behaviour (2024)

Abstract The widespread use of video games has raised concerns about their potential negative impact on mental well-being. Nevertheless, the empirical evidence supporting this notion is largely based on correlational studies, warranting further investigation into the causal relationship. Here we identify the causal effect of video gaming on mental well-being in Japan (2020–2022) using game console lotteries as a natural experiment. Employing approaches designed for causal inference on survey data ( n = 97,602), we found that game console ownership, along with increased game play, improved mental well-being. The console ownership reduced psychological distress and improved life satisfaction by 0.1–0.6 standard deviations. Furthermore, a causal forest machine learning algorithm revealed divergent impacts between different types of console, with one showing smaller benefits for adolescents and females while the other showed larger benefits for adolescents. These findings highlight the complex impact of digital media on mental well-being and the importance of considering differential screen time effects.
Chronic adaptive deep brain stimulation versus conventional stimulation in Parkinson’s disease: a blinded randomized feasibility trial
Authors: Carina R. Oehrn, Stephanie Cernera, Lauren H. Hammer, Maria Shcherbakova, Jiaang Yao, Amelia Hahn, Sarah Wang, Jill L. Ostrem, Simon Little, Philip A. Starr
Journal: Nature Medicine (2024)
Guidelines Development Group for the British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma
Authors: Shahid A Khan, Simon M Rushbrook, Timothy James Kendall, Yoh Zen, Raneem Albazaz, Prakash Manoharan, Stephen P Pereira, Richard Sturgess, Brian R Davidson, Hassan Z Malik, Derek Manas, Nigel Heaton, K Raj Prasad, Juan W Valle, Rebecca Goody, Maria Hawkins, Wendy Prentice, Helen Morement, Martine Walmsley, John Bridgewater
Journal: Gut (2024)
Efficacy and safety of sequential therapy with subcutaneous belimumab and one cycle of rituximab in patients with systemic lupus erythematosus: the phase 3, randomised, placebo-controlled BLISS-BELIEVE study
Authors: Cynthia Aranow, Cornelia F Allaart, Zahir Amoura, Ian N Bruce, Patricia C Cagnoli, Walter W Chatham, Kenneth L Clark, Richard Furie, James Groark, Murray B Urowitz, Ronald van Vollenhoven, Mark Daniels, Norma Lynn Fox, Yun Irene Gregan, Robert B Henderson, André van Maurik, Josephine C Ocran-Appiah, Mary Oldham, David A Roth, Don Shanahan, Paul P Tak, Yk Onno Teng
Journal: Annals of the Rheumatic Diseases (2024)

Disease activity control in patients with systemic lupus erythematosus (SLE) with corticosteroid and immunosuppressant withdrawal is a treatment goal. We evaluated whether this could be attained with sequential subcutaneous belimumab (BEL) and one cycle of rituximab (RTX).
Error in Days for Outcome Ascertainment in Study Comparing Antibiotic Treatment of Acute Sinusitis in Children and Adolescents
Authors: Timothy J. Savage
Journal: JAMA (2024)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sex Differences in Case-Fatality Rates of Stroke
Authors: Faizan Khan, Michael D. Hill
Journal: JAMA Neurology (2024)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Neurology HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Neurology journal
Author Correction: Specific CD4+ T cell phenotypes associate with bacterial control in people who ‘resist’ infection with Mycobacterium tuberculosis
Authors: Meng Sun, Jolie M. Phan, Nathan S. Kieswetter, Huang Huang, Krystle K. Q. Yu, Malisa T. Smith, Yiran E. Liu, Chuangqi Wang, Sanjana Gupta, Gerlinde Obermoser, Holden Terry Maecker, Akshaya Krishnan, Sundari Suresh, Neha Gupta, Mary Rieck, Peter Acs, Mustafa Ghanizada, Shin-Heng Chiou, Purvesh Khatri, W. Henry Boom, Thomas R. Hawn, Catherine M. Stein, Harriet Mayanja-Kizza, Mark M. Davis, Chetan Seshadri
Journal: Nature Immunology (2024)
Sex Differences in Case-Fatality Rates of Stroke—Reply
Authors: Daniela Renedo, Kevin N. Sheth
Journal: JAMA Neurology (2024)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Neurology HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Neurology journal
Telehealth Mindfulness-Based Interventions for Chronic Pain
Authors: Diana J. Burgess, Collin Calvert, Emily M. Hagel Campbell, Kelli D. Allen, Ann Bangerter, Kimberly Behrens, Mariah Branson, Gert Bronfort, Lee J. S. Cross, Roni Evans, John E. Ferguson, Jessica K. Friedman, Alexander C. Haley, Brent Leininger, Mallory Mahaffey, Marianne S. Matthias, Laura A. Meis, Melissa A. Polusny, J. Greg Serpa, Stephanie L. Taylor, Brent C. Taylor
Journal: JAMA Internal Medicine (2024)

Although mindfulness-based interventions (MBIs) are evidence-based treatments for chronic pain and comorbid conditions, implementing them at scale poses many challenges, such as the need for dedicated space and trained instructors.
Disaggregated Suicide Mortality Rates Among Asian American Youths and Young Adults by Ethnic Subgroup
Authors: Anthony L. Bui, Isaac C. Rhew, Frederick P. Rivara, Tumaini R. Coker
Journal: JAMA Pediatrics (2024)

This cross-sectional study examines suicide mortality rates among Asian American youths and young adults overall and by ethnic subgroup from 2018 to 2021.
Clinician Specialty and HIV PrEP Prescription Reversals and Abandonments
Authors: Shivani Bakre, Hsien-Yen Chang, Jalpa A. Doshi, William C. Goedel, Parya Saberi, Philip A. Chan, Amy Nunn, Lorraine T. Dean
Journal: JAMA Internal Medicine (2024)

Importance Clinicians are a key component of preexposure prophylaxis (PrEP) care. Yet, no prior studies have quantitatively investigated how PrEP adherence differs by clinician specialty. Objective To understand the association between prescribing clinician specialty and patients not picking up (reversal/abandonment) their initial PrEP prescription. Design, Setting, and Participants This cross-sectional study of patients who were 18 years or older used pharmacy claims data from 2015 to 2019 on new insurer-approved PrEP prescriptions that were matched with clinician data from the US National Plan and Provider Enumeration System. Data were analyzed from January to May 2022. Main Outcomes and Measures Clinician specialties included primary care practitioners (PCPs), infectious disease (ID), or other specialties. Reversal was defined as a patient not picking up their insurer-approved initial PrEP prescription. Abandonment was defined as a patient who reversed and still did not pick their prescription within 365 days. Results Of the 37 003 patients, 4439 (12%) were female and 32 564 (88%) were male, and 77% were aged 25 to 54 years. A total of 24 604 (67%) received prescriptions from PCPs, 3571 (10%) from ID specialists, and 8828 (24%) from other specialty clinicians. The prevalence of reversals for patients of PCPs, ID specialists, and other specialty clinicians was 18%, 18%, and 25%, respectively, and for abandonments was 12%, 12%, and 20%, respectively. After adjusting for confounding, logistic regression models showed that, compared with patients who were prescribed PrEP by a PCP, patients prescribed PrEP by ID specialists had 10% lower odds of reversals (odds ratio [OR], 0.90; 95% CI, 0.81-0.99) and 12% lower odds of abandonment (OR, 0.88; 95% CI, 0.78-0.98), while patients prescribed by other clinicians had 33% higher odds of reversals (OR, 1.33; 95% CI, 1.25-1.41) and 54% higher odds of abandonment (OR, 1.54; 95% CI, 1.44-1.65). Conclusion The results of this cross-sectional study suggest that PCPs do most of the new PrEP prescribing and are a critical entry point for patients. PrEP adherence differs by clinician specialties, likely due to the populations served by them. Future studies to test interventions that provide adherence support and education are needed.
Effect of Messaging on Support for Breast Cancer Screening Cessation Among Older US Women
Authors: Nancy L. Schoenborn, Sarah E. Gollust, Rebekah H. Nagler, Craig E. Pollack, Cynthia M. Boyd, Qian-Li Xue, Mara A. Schonberg
Journal: JAMA Network Open (2024)

Many older women are screened for breast cancer beyond guideline-recommended thresholds. Messaging holds promise to reduce overscreening.
Further Study Needed on Antihypertensive Medications and Fracture Risks
Authors: Junxian Gu, Yang Qiao, Zining Luo
Journal: JAMA Internal Medicine (2024)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Overcoming Challenges to Implementing Mindfulness-Based Pain Interventions
Authors: Dan Cherkin
Journal: JAMA Internal Medicine (2024)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Localized Nicardipine Release Implants for Prevention of Vasospasm After Aneurysmal Subarachnoid Hemorrhage
Authors: Lars Wessels, Stefan Wolf, Tiziana Adage, Jörg Breitenbach, Claudius Thomé, Johannes Kerschbaumer, Martin Bendszus, Matthias Gmeiner, Andreas Gruber, Dorothee Mielke, Veit Rohde, Maria Wostrack, Bernard Meyer, Jens Gempt, Gerhard Bavinzski, Dorian Hirschmann, Peter Vajkoczy, Nils Hecht
Journal: JAMA Neurology (2024)

Cerebral vasospasm largely contributes to a devastating outcome after aneurysmal subarachnoid hemorrhage (aSAH), with limited therapeutic options.
Contextual Deprivation, Race and Ethnicity, and Income in Air Pollution and Cardiovascular Disease
Authors: Jiajun Luo, Andrew Craver, Zhihao Jin, Liang Zheng, Karen Kim, Tamar Polonsky, Christopher O. Olopade, Jayant M. Pinto, Habibul Ahsan, Briseis Aschebrook-Kilfoy
Journal: JAMA Network Open (2024)

Socioeconomically disadvantaged subpopulations are more vulnerable to fine particulate matter (PM2.5) exposure. However, as prior studies focused on individual-level socioeconomic characteristics, how contextual deprivation modifies the association of PM2.5 exposure with cardiovascular health remains unclear.
Lecanemab and Vascular-Amyloid Deposition in Brains of People With Down Syndrome
Authors: Lei Liu, Adriana Saba, Jesse R. Pascual, Michael B. Miller, Elizabeth L. Hennessey, Ira T. Lott, Adam M. Brickman, Donna M. Wilcock, Jordan P. Harp, Frederick A. Schmitt, Dennis J. Selkoe, Jasmeer P. Chhatwal, Elizabeth Head
Journal: JAMA Neurology (2024)

Importance Anti-β-amyloid immunotherapy using lecanemab is becoming increasingly available to patients with Alzheimer disease (AD). Individuals with Down syndrome (DS) develop AD neuropathology by age 40 years, representing a significant cohort of genetically determined AD. Objective To investigate the binding properties of lecanemab in the brains of people with DS, in anticipation of their inclusion in clinical trials or access to antiamyloid immunotherapies. Design, Setting, Participants The study included cases of postmortem brain tissue analysis from 15 individuals with DS aged 43 to 68 years that were acquired from Alzheimer Disease research centers at the University of California, Irvine and the University of Kentucky from 2008 to 2021. Data were analyzed from August 2023 through May 2024. Exposure The binding properties of lecanemab were assessed in brain tissue. Main Outcome The primary outcome was the extent of lecanemab binding to amyloid plaques and brain blood vessels. Results Tissue from 15 people (8 were female [53%]) with DS ranging in age from 43 to 68 (mean, 56.6) years were included in the study. Lecanemab-labeled amyloid plaques appeared in all 15 DS cases studied, indicating potential target engagement. However, extensive binding of lecanemab to brain blood vessels in DS was observed, raising significant safety concerns. These findings underscore the necessity for clinical trials of lecanemab in people with DS to evaluate both safety and efficacy, particularly in individuals older than 43 years. Conclusions and Relevance These findings suggest significant binding of lecanemab to cerebral amyloid angiopathy in DS. Lecanemab should be rigorously tested in clinical trials for AD in the DS population to determine its safety and efficacy, especially in those older than 43 years.
Paternal Preconception Hepatitis B Virus Infection and Risk of Congenital Heart Disease in Offspring
Authors: Ying Yang, Meiya Liu, Jiancheng Han, Hanbin Wu, Chuanyu Zhao, Xinyi Lyu, Xuan Hu, Youhong Liu, Die Xu, Wenlu Xie, Jiaxin Huang, Siyu Wu, Jiaxin Li, Jueming Lei, Ya Zhang, Hongguang Zhang, Yuan He, Zuoqi Peng, Yuanyuan Wang, Haiping Shen, Qiaomei Wang, Yiping Zhang, Donghai Yan, Long Wang, Yihua He, Xu Ma
Journal: JAMA Pediatrics (2024)

Previous evidence suggests that maternal hepatitis B virus (HBV) infection during prepregnancy or pregnancy is associated with congenital heart diseases (CHDs) in offspring. However, the association of paternal HBV infection with CHDs is not well examined.
Promoting Resilience in Stress Management for Adolescents With Type 1 Diabetes
Authors: Joyce P. Yi-Frazier, Marisa E. Hilliard, Maeve B. O’Donnell, Chuan Zhou, Britney M. Ellisor, Samantha Garcia Perez, Brenda Duran, Yuliana Rojas, Faisal S. Malik, Daniel J. DeSalvo, Catherine Pihoker, Miranda C. Bradford, Samantha Scott, Sridevi Devaraj, Abby R. Rosenberg
Journal: JAMA Network Open (2024)

Type 1 diabetes (T1D) requires demanding self-management health behaviors, and adolescents with T1D are at risk for poor psychosocial and medical outcomes. Developing resilience skills may help adolescents with T1D and elevated distress navigate common stressors and achieve positive outcomes.