Effects of Pitavastatin on Coronary Artery Disease and Inflammatory Biomarkers in HIV
Authors: Michael T. Lu, Heather Ribaudo, Borek Foldyna, Markella V. Zanni, Thomas Mayrhofer, Julia Karady, Jana Taron, Kathleen V. Fitch, Sara McCallum, Tricia H. Burdo, Kayla Paradis, Sandeep S. Hedgire, Nandini M. Meyersohn, Christopher DeFilippi, Carlos D. Malvestutto, Audra Sturniolo, Marissa Diggs, Sue Siminski, Gerald S. Bloomfield, Beverly Alston-Smith, Patrice Desvigne-Nickens, Edgar T. Overton, Judith S. Currier, Judith A. Aberg, Carl J. Fichtenbaum, Udo Hoffmann, Pamela S. Douglas, Steven K. Grinspoon, Carl J. Fichtenbaum, Judith A. Aberg, Eric S. Daar, Babafemi Taiwo, Susan L. Koletar, Kara W. Chew, Susan J. Little, Sonya L. Heath, Jeffrey M. Jacobson, Rajesh Gandhi, Gregory Robbins, Rachel M. Presti, Marshall Glesby, Annie Luetkemeyer, Pablo Tebas, Sharon A. Riddler, Michael P. Dube, Jorge L. Santana-Bagur, Beverly E. Sha, Jennifer Manne, Roberto Arduino, Charles W. Flexner, David W. Haas, David A. Wohl, Magdalena E. Sobieszczyk, Karen T. Tashima, Sonal S. Munsiff, Rachel Bender Ignacio, Kristen Marks, Cornelius Van Dam, Shobha Swaminathan, Thomas B. Campbell, Beverly Alston-Smith, Patricia Bandettini, Gerald Bloomfield, Judith Currier, Patrice Desvigne-Nickens, Marissa Diggs, Pamela S. Douglas, Kathleen V. Fitch, Steven K. Grinspoon, Peter Kim, Michael T. Lu, Kayla Paradis, Heather J. Ribaudo, Yves Rosenberg, James Troendle, Mark Byroads, Elaine Gershman, Folake Lawal, Jorge Leon-Cruz, Rochelle Louis, Cheryl Lowe, Eva Moy, Triin Umbleja, Namrata Upadhyay, Stephen Wiviott, Kenneth Wood, Oladapo Anthony, Radhika Barve, Fred Bone, Selina Bannoo, Annie Duffy, Carl Fletcher, Madison Green, Nory Klop-Packel, Sara McCallum, Emilia Norton, Jennifer Nowak, Maria Sanchez Grande, Sue Siminski, Eloise Walker, David Vlieg, Tricia Burdo, Laura Moran, Jhoanna Roa, Heather Sprenger, Bola Adedeji, Oladapo Alli, Blanca Castillo, Joan Dragavon, Keisha Easley, Julian Falutz, Ewelinka Grzejka, Erin Hoffman, Yuji Liao, Sara Looby, Dana Nohynek, Mary Pate, James Rooney, Akbar Shahkolahi, Craig Sponseller, Kenneth Williams, Markella Zanni, Kate Borloglou, Meredith Clement, Allison Eckard, Rebecca LeBlanc, Carlos Malvestutto, Edgar T Overton, Karl Shaw, Virginia Triant, Amy Kantor, Jennifer M. Manne-Goehler, Kate Starr, Ronald Barnett, Jane Baum, Cindy Coates, Sandra W. Cordoso, Christie Lyn Costanza, Sylvia Davila, Dushyantha Jayaweera, Teri Greenfield, Howard Gutzman, Regina Harden, Sarah Henn, MJ Humphries, Mamta Jain, David Klein, Sharon Kohrs, Javier Lama, Jessica Landis, Jaclyn Leone, Rita Lira, Maria Martinez, Richard Novak, Karen Reese, Breno Santos, Jenese Tucker, Aimee Wilkin, Tomeka Wilson, Borek Foldyna, Julia Karady, Thomas Mayrhofer, Audra Sturniolo, Barbara Bastow, Francoise Giguel, Nada Saleh, John Ward, Erin Cherban, Sean Brummel, Janeway Granche, Carlee Moser, Pawel Paczuski, Laura Smeaton, Claire Benjamin, Tanisha Cadet, Evelynne Fulda, Jacqueline Murphy, Alicia Diggs, Robert Ettinger, Angel Hernandez, Janice Jarrells, Shirley Selvage, Sandeep Hedgire, Udo Hoffman, Nina M. Meyersohn, Jana Taron, Anthony Holguin, Gregory Pavlov, Scott Hammer, Martin Hirsch, JoAnn Manson, Paul Ridker, James Stein, Russel Tracy, James Udelson, Esteban Martinez, Tim Leaver, Anton Pozniak, Kathy Melbourne, Matthew Budoff, Ben Cheng, Sara Goldkind, Carl Grunfeld, Robert Harrington, Donald Lloyd-Jones, Jennifer Robinson, Lynn Sleeper, George Sopko, Paul Volberding, Fassil Ketema, Karin Klingman, Keisha Johnson, Mark Mishkin, Daniella Livnat, Akin Ojumu, Alba Sierto
Journal: JAMA Cardiology (2024)

Cardiovascular disease (CVD) is increased in people with HIV (PWH) and is characterized by premature noncalcified coronary plaque. In the Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE), pitavastatin reduced major adverse cardiovascular events (MACE) by 35% over a median of 5.1 years.