Fludarabine, Cytarabine, Granulocyte Colony-Stimulating Factor, and Idarubicin With Gemtuzumab Ozogamicin Improves Event-Free Survival in Younger Patients With Newly Diagnosed AML and Overall Survival in Patients With <i>NPM1</i> and <i>FLT3</i> Mutations
Authors: Nigel H. Russell, Charlotte Wilhelm-Benartzi, Jad Othman, Richard Dillon, Steven Knapper, Leona M. Batten, Joanna Canham, Emily L. Hinson, Sophie Betteridge, Ulrik Malthe Overgaard, Amanda Gilkes, Nicola Potter, Priyanka Mehta, Panagiotis Kottaridis, Jamie Cavenagh, Claire Hemmaway, Claire Arnold, Sylvie D. Freeman, Mike Dennis, Maria Kallenbach, Marianne Severinsen, Mette Holm, Jan Maxwell Norgaard, Hans Beier Ommen, Dominic Culligan, Jane Tighe, Jenny Craig, Charles Crawley, Pramila Krishnamurthy, Walid Sadik, Jeffery Smith, Ranjit Dasgupta, Leanne Berkhan, Peter Bowett, Richard Doocey, Shannon Emmett, Timothy Hawkins, Nigel Patton, Lucy Pemberton, Alison Milne, Ashok Roy, Sylwia Simpson, Claire Arnold, Robert Cuthbert, Damian Finnegan, Mary Francis McMullin, Victoria Pechey, Richard Lovell, Donald Milligan, Shankara Paneesha, Paul Cahalin, P. Kelsey, Sam Ackroyd, Adrian Wiliams, Roger Evely, David Marks, Priyanka Mehta, Andrew Fletcher, Maryam Al-Ani, Khalil Ahmed, Richard Lush, Adam Rye, Robert Cutting, Andrew Fletcher, Emma Welch, Mark Wodzinski, Andrew Butler, Liam Fernyhough, Peter Ganly, Steve Gibbons, Mark Smith, Ruth Spearing, Andy Peniket, Faye Hatcliffe, Amit Patel, Kathrine Lindsay, Gillian Brearton, Salah Tuegar, S. Gandhi Anna Cowley, Adrian Copplestone, Hannah Hunter, Patrick Medd, Tim Nokes, Simon Rule, Wayne Thomas, Robert Cutting, Joe Joseph, Stuti Kaul, Youssef Sorour, Shingi Chvuka, Hilda Mangos, Annette Neylon, Katrina Farrell, Hugh Edwards, Katharine Hanlon, Tom Fail, Margaret Goodrick, Earnest Heartin, Christine Hoyle, Adam Rye, Robert Carr, Kavita Raj, Morten Krogh Jensen, Riaz Janmohamed, Richard Kaczmarski, Taku Sugai, Debo Ademokun, Isobel Chalmers, Andrew Hodson, Cesar Gomez, Shala Sadullah, Mark Kwan, Karyn Longmuir, Isaac Wilson-Morkeh, Ann Hunter, Murray Martin, Kandeepan Saravanamuttu, Gamal Sidra, Sarah Burns, Simon Gibbs, Eleni Tholouli, Maadh Aldouri, Vivienne Andrews, Ayed Eden, Moez Dungarwalla, Denise White, Jane Laird, Lindsey Mitchell, John Murphy, Pamela Paterson, Alaeddin Raafat, Deepak Mannari, Simon Davies, Belinda Austen, Sarah Allford, Sudhakar Kakalamudi, Supratik Basu, Sunil Hada, Abraham Jacob, Alan MacWhonell, Alison McCaig, Keith Gelly, Ron Kerr, David Meiklejohn, Sudhir Tauro, Matthew Lawes, Angela Bowen, Suchitra Krishnamurthy, Jenny Byrne, Emma Dasgupta, Nigel Russell, Simone Stokley, Lone Friis, Claus Marcher, Bart Bake, Mary Chapple, Paul Moreton, Asad Omran, Kavita Patil, David Wright, Fergus Jack, Rebecca Maddams, Robert Corser, Tanya Cranfield, Helen Dignum, Mary Ganczakowski, Christopher Jones, Charles Craddock, Paula Moss, Jim Murray, Claire Hemmaway, Joanne Craig, Peter Forsyth, Chris Lush, Ole Wei Bjerrum, Niels Borregaard, Peter Kampmann, Lars Kjeldsen, Ove Juul Nielsen, Carsten Niemann, Soeren Lykke Petersen, Lene Udby Peter Møller, Arun Alfred, Helen Barker, Richard Went, Henri Groch, Stuart Mucklow, Rebecca Sampson, Joseph Chacko, Rachel Hall, Renata Walewska, Desmond Creach, Bryson Pottinger, Juanah (Jo) Addada, Malcolm Hamilton, Paul Kerr, Loretta Ngu, Claudius Rudin, Jackie Ruell, Chris Dalley, Harpreet Kaur, John Reilly, John Snowden, Paul Ferguson, Peter Dyer, Deepak Chandra, Johannes DeVos, Elisabeth Grey-Davies, Louise Hendry, Timothy Corbett, Josephine Crowe, Christopher Knechtli, Sarah Wexler, Savio Fernandes, Jeff Neilson, John Houghton, Simon Jowitt, Rowena Thomas-Dewing, Mark Williams, Sonya Zaman, Jonathan Cullis, Tamara Everington, Effie Grand, Yasmin Hasan, Richard Murrin, Farooq Wandoo, Saad Ismail, Unmesh Mohite, Hamdi Sati, Matthew Jenner, Kim Orchard, Deborah Richardson, Kayleigh McCloskey, Kate Xu Chin, Neoh Fenella Willis, Amit Sud, Maged Gharib, Toby Nicholson, David Bowen, Sarah Janes, Helen Eagleton, Anne-Marie O'Hea, Jonathan Pattinson, Victoria Hervey, Simon Lyons, Scott Marshall, Annette Nicolle, Maria Vavyla, Jordan Burgess, Tim Somervaille, Sven Somerfield, Mohd Mamat, Jo Tomlins, Sana Salesh, Marianna David, Jamie Maddox, Diane Plews, Ray Dang, Mike Potter, Lauren Ellis, Emma Nicholson, Sally Keat, Thubeena M. Ahmed Alhassani, Farahn Anjum, Poulami Chatterjee, Atanas Stanchev, Jayne Peters, Sarah Lindsay-Holmes Srividhya, Senthil S. Chodhouri, Heather Eve, Steve Smith, Patrick Roberts, Nicholas Rymes, Rui Zhao New Oo, Kirit Ardeshna, Piers Blombery, Asim Khwaja, David Linch, Rakesh Popat, Andres Virchis, Kwee Yong, Victoria McIntyre, Gillian Horne, Syed Bokhari, Anton Borg, Oliver Chapman, Beth Harrison, Nicholas Jackson, Shailesh Jobanputra, Mekkali Narayanan, Peter Rose, Hajer Oun, Matthew Powell, Julie Gilles, Alison Laing, Ian Devanny, Gillian Horne, Lea Haskins, Paul Micallef-Eynaud, Peter Maclean, Caroline Alvares, Jonathan Kell, Steve Knapper, Kerri Davidson, Lorna McLintock, Stephen Rogers, Peter Williamson, Gillian Corbett, Hugh Goodman, Shahid Islam, Humphrey Pullon, Peter Johnson, P.H. Roddie, Elizabeth Maughan, Juliet Mills, Salim Shafeek, Santosh Narat, Robin Aitchison, Jonathan Pattinson, Lee Bond, Laura Munro, David Edwards
Journal: Journal of Clinical Oncology (2024)

To determine the optimal induction chemotherapy regimen for younger adults with newly diagnosed AML without known adverse risk cytogenetics.