tbuckley/cabot-search huggingface dataset:
THU-135 Real-world study of reasons for non-utilization of second-line treatment in patients with primary biliary cholangitis
Authors: Seema T. Meloni, Claudia O. Zein, Allison R. Smither, Anushree Iyengar, Ediz S. Calay, Tyler E. Wagner, Rohit K. Yenukoti, Christelle Pommie, Olivier Gattolliat, Vitalii Doban, Brian D. Juran, Konstantinos N. Lazaridis
Journal: Journal of Hepatology (2024)
SAT-159-YI Mitochondrial integrity and auto (mito)phagy are disrupted in experimental models of primary biliary cholangitis, contributing to disease pathogenesis
Authors: Irune Lasa-Elosegi, Laura Izquierdo-Sánchez, Paula Olaizola, Ainhoa Lapitz, Luis Bujanda, Matxus Perugorria, Pedro M. Rodrigues, Jesus Maria Banales
Journal: Journal of Hepatology (2024)
FRI-542 Induced pluripotent stem cell-derived hepatocytes revisited: improved liver functionality compared to liver cancer cell lines and a better model for pre-clinical large-scale therapeutic screening and drug safety
Authors: Magdalena Lukasiak, Gemma Gatti, George Kiloh, Samuel Chung, Ka Cheung, Chloe Robinson, Bhavik Chouhan, Dominic Williams, Lia Panman, Carlos Gil, Nikolaos Nikolaou
Journal: Journal of Hepatology (2024)
THU-133-YI Radiomics for prognostication in primary sclerosing cholangitis: a proof-of-concept using GLRLM run entropy
Authors: Laura Cristoferi, Cesare Maino, Davide Bernasconi, Alberto Savino, Ilaria Ripamonti, Miki Scaravaglio, Eugenia Vittoria Pesatori, Daphne D'Amato, Alessio Gerussi, Chiara Alberzoni, Maria Grazie Valsecchi, Rocco Corso, Davide Ippolito, Pietro Invernizzi, Elisabetta De Bernardi, Marco Carbone
Journal: Journal of Hepatology (2024)
TOP-169 Sex, ethnicity and clinical outcomes in autoimmune hepatitis: results from a large multicenter longitudinal cohort
Authors: Ellina Lytvyak, Devika Shreekumar, Gideon M. Hirschfield, Christina Plagiannakos, Hin HIn Ko, Mark G Swain, Julian Hercun, Lawrence Worobetz, Catherine Vincent, Jennifer Flemming, Karim Qumosani, Tianyan Chen, Dusanka Grbic, Angela Cheung, Narmeen Umar, Iffat Iqbal, Madeline Cameron, Aliya Gulamhusein, Andrew L. Mason, Bettina Hansen, Aldo J Montano-Loza
Journal: Journal of Hepatology (2024)
SAT-125 Comparison of endoscopic variceal ligation and endoscopic cyanoacrylate injection for the treatment of acute variceal bleeding from the cardia to the lesser curvature of the stomach
Authors: Yu-Fu Chen, Tsung-Chieh Yang, Ping-Han Hsieh, Yu-Jen Chen, Jiing-Chyuan Luo, Ming-Chih Hou
Journal: Journal of Hepatology (2024)
THU-109 Increasing prevalence of primary biliary cholangitis in The Netherlands
Authors: Rozanne C. de Veer, Maria C. van Hooff, Ellen Werner, Ulrich Beuers, Joost P.H. Drenth, Frans J.C. Cuperus, Bart van Hoek, Bart J. Veldt, Michael Kempt-Kropp, Suzanne van Meer, Robert C. Verdonk, Hajo J. Flink, Jan Maarten Vrolijk, Tom J.G. Gevers, Cyriel Y. Ponsioen, Martijn J. ter Borg, Khalida Soufidi, Femke Boersma, Hendrik J.M. de Jonge, Frank H.J. Wolfhagen, L.C. Baak, Susanne L. Onderwater, Jeroen D. van Bergeijk, Paul G. van Putten, Gijs J. de Bruin, Rob P.R. Adang, Nieves Aparicio Pages, Wink de Boer, Frank ter Borg, Hanneke van Soest, Harry L.A. Janssen, Bettina E. Hansen, Nicole S. Erler, Adriaan J. van der Meer
Journal: Journal of Hepatology (2024)
THU-106-YI Prospective european reference network registry (R-LIVER) supports improvement in bone disease care delivery at local level for patients with autoimmune liver diseases and enables detailed description of risk elements
Authors: Boglarka Bozso, Sandor Mogyorossy, David Tornai, Patricia Kovats, Boglarka Balogh, Nora Sipeki, Fruzsina Olah, Péter Antal-Szalmás, Zsuzsanna Vitalis, Istvan Tornai, Christoph Schramm, Maria Papp
Journal: Journal of Hepatology (2024)
WED-518-YI Protein-modulated microbiota for fecal transplantation improves metabolic functions in alcohol-related liver disease model
Authors: Nishu Choudhary, Ashi Mittal, Kavita Yadav, Jaswinder Maras, Anupama Parasar, Shiv Kumar Sarin, Shvetank Sharma
Journal: Journal of Hepatology (2024)
TOP-168-YI Urgent call to action: people living with primary sclerosing cholangitis-inflammatory bowel disease (PSC-IBD) lose 10 years of life compared to those with IBD alone
Authors: Kristel Leung, Wenbin Li, Bettina E. Hansen, Amanda Ricciuto, Eric Benchimol, Aliya Gulamhusein, Jennifer Flemming, Gideon M. Hirschfield
Journal: Journal of Hepatology (2024)
WED-523 Sulphated progesterone metabolites undergo apical sodium bile acid transporter-mediated enterohepatic recycling and stimulate glucagon-like peptide 1 and peptide YY release
Authors: Alice Mitchell, Iain Tough, Caroline Ovadia, Anita Lövgren-Sandblom, Jenny Chambers, Anastasia Tsakmaki, Patricia Pedro, Gavin Bewick, Helen Cox, Catherine Williamson
Journal: Journal of Hepatology (2024)
WED-519-YI Criss-cross fecal microbiota transplant identifies hepatic steroid biosynthesis and linoleic acid metabolism linked with liver injury and dysbiosis in rat
Authors: Manisha Yadav, Jaswinder Maras, Neha Sharma, Nupur Sharma, Gaurav Tripathi, Sadam H. Bhat, Sushmita Pandey, Vasundhra Bindal, Babu Mathew, Anupama Kumari, Shiv Kumar Sarin
Journal: Journal of Hepatology (2024)
SAT-135 Soluble urokinase plasminogen activator receptor (suPAR) levels predict survival in patients with portal hypertension undergoing TIPS
Authors: Sven H. Loosen, Fabian Benz, Raphael Mohr, Philipp Reuken, Theresa Hildegard Wirtz, Wenyi Gu, Lioba Junker, Christian Jansen, Carsten Meyer, Michael Praktiknjo, Alexander Wree, Johanna Reissing, Münevver Demir, Mihael Vucur, Robert Schierwagen, Andreas Stallmach, Anselm Kunstein, Johannes Bode, Christian Trautwein, Frank Tacke, Tom Luedde, Tony Bruns, Jonel Trebicka, Christoph Roderburg
Journal: Journal of Hepatology (2024)
WED-521-YI Tissue-specific roles of Farnesoid X Receptor in gut-liver axis and influence on progressive cholestatic liver injury
Authors: Lina Ludwigs, Ines Volkert, Mona Peltzer, Antonio Molinaro, Marcus Henricsson, Hanns-Ulrich Marschall, Karolina Edlund, Kai Markus Schneider, Thomas Longerich, Peter Boor, Jan G. Hengstler, Christian Trautwein, Lena Susanna Candels
Journal: Journal of Hepatology (2024)
THU-120-YI The impact of ursodeoxycholic acid on biochemistry of patients with primary biliary cholangitis in a nationwide cohort
Authors: Ellen Werner, Maria C. van Hooff, Gerjan J. van der Maas, Rozanne C. de Veer, Ulrich Beuers, Joost P.H. Drenth, Frans J.C. Cuperus, Bart van Hoek, Bart J. Veldt, Michael Klemt-Kropp, Suzanne van Meer, Robert C. Verdonk, Hajo J. Flink, Jan Maarten Vrolijk, Tom J.G. Gevers, Cyriel Y. Ponsioen, Sander de Kort, Paul G. van Putten, Djuna L. Cahen, Lauren A. van der Waaij, Hans H.K. Thio, Tim C.M.A. Schreuder, Lisette J.H. van Dam, Ludger S.M. Epping, Matthias C. Jurgens, Marcel Cazemier, J. van Kemenade, Edith M.M. Kuiper, Menno Beukema, Martijn J. ter Borg, Khalida Soufidi, Harry L.A. Janssen, Bettina E. Hansen, Nicole S. Erler, Adriaan J. van der Meer
Journal: Journal of Hepatology (2024)
THU-160 Long-term variability of pruritus in primary sclerosing cholangitis and implications for future clinical trial design
Authors: Nasir Hussain, James Ferguson, Nadir Abbas, Usha Gungabissoon, Khushpreet Bhandal, Emma Burke, Diana Hull, Penelope Rogers, Linda Casillas, Sumanta Mukherjee, Andrea Ribeiro, Megan McLaughlin, Martine Walmsley, Paula Hanford, Palak J. Trivedi
Journal: Journal of Hepatology (2024)
THU-556 Liver fibrosis in NLRP3tm1Hhf/J knockout mice suffering from apical periodontitis
Authors: Cristiane Cantiga, Mariana Justo, Flávio Faria, Pedro Oliveira, Laís Barroti, Almir Rodrigues, Nathália Machado, Juliana Goto, Edilson Ervolino, Tiago Pinheiro, Luciano Cintra
Journal: Journal of Hepatology (2024)
THU-526 The hepatoprotective role of ECM1: inhibition of mediators of latent TGF-β1 activation and implications for anti-fibrotic treatment strategies in chronic liver disease
Authors: Frederik Link, Yujia Li, Jieling Zhao, Stefan Munker, Weiguo Fan, Zeribe Nwosu, Ye Yao, Seddik Hammad, Peter ten Dijke, Matthias Ebert, Roman Liebe, Honglei Weng, Dirk Drasdo, Steven Dooley, Sai Wang
Journal: Journal of Hepatology (2024)
SAT-176 Itg-Cre/DTA mice develop the autoimmune biliary disease that serologically and pathogenically models human primary biliary cholangitis
Authors: Jiaqi Zhang, Mayu Ouchi, Ryo Nakagawa, Akane Kurosugi, Goto Chihiro, Ryuta Kojima, Tatsuya Kaneko, Yuki Ohta, Motoyasu Kan, Masato Nakamura, Shingo Nakamoto, Jun Kato, Yoshihiro Hirata, Naoya Kato
Journal: Journal of Hepatology (2024)
WED-548 Rifaximin-alpha acts through increased abundance of Lactobacillus spp. in murine models of chronic liver disease
Authors: Maximilian Joseph Brol, Camila Alvarez-Silva, Robert Schierwagen, Frank Erhard Uschner, Sabine Klein, Jonel Trebicka, Manimozhiyan Arumugam
Journal: Journal of Hepatology (2024)
SAT-175 PPAR-delta activation with seladelpar regulates cholangiocyte inflammation
Authors: Xia Wu, Yen-Wen Chen, Jiangao Song, Edward Cable, Jeff Johnson, Joanne Elliott, Francisco Caballero-Camino, Xin Chen, Robert Martin, Jeffrey Stebbins, Jesús M. Bañales, Charles A. McWherter
Journal: Journal of Hepatology (2024)
THU-542 Inhibition of hyaluronic acid synthesis by hyaluronan synthase 2 targeting siRNA downregulates expression of chemokine (C-X-C motif) ligand 16 and suppresses liver fibrosis in mice
Authors: Noreen Halimani, Mikhail Nesterchuk, Alexandra Tsitrina, Marat Sabirov, Irina Andreichenko, Nataliya Dashenkova, Alexey Kulikov, Timofei Zatsepin, Roman Romanov, Arsen Mikaelyan, Yuri Kotelevtsev
Journal: Journal of Hepatology (2024)
SAT-080-YI Residual minimal ascites 3 months after TIPS implantation indicates risk of further decompensation and death
Authors: Lukas Hartl, Jim Benjamin Mauz, Andrea Kornfehl, Sarah Lisa Schutte, Paul Hemetsberger, Theresa Mullner-Bucsics, Mathias Jachs, Anja Tiede, Hannah Schneider, Michael Schwarz, Bernhard Meyer, Lukas Reider, Maria Schoder, Michael Trauner, Mattias Mandorfer, Benjamin Maasoumy, Tammo Lambert Tergast, Thomas Reiberger
Journal: Journal of Hepatology (2024)
FRI-122 Decompensated cirrhosis is associated with disruption of nuclear positioning in skeletal muscle and selective atrophy of type II myofibers
Authors: Aldo J Montano-Loza, Maryam Motamedrad, Maryam Ebadi, Norberto Sanchez-Fernandez, Alessandro Parente, Abha Dunichand-Hoedl, Elora Rider, Norman Kneteman, James Shapiro, David Bigam, Khaled Dajani, Blaire Anderson, Vickie Baracos, Vera C. Mazurak
Journal: Journal of Hepatology (2024)
SAT-123 Evaluation of portal hemodynamics after etiological factor removal and persistence of varices in patients with an HVPG &lt;10 mmHg and NITs within the grey zone
Authors: Pol Olivas Alberch, Alexandre Soler, Luis Téllez, Jose A. Carrión, Edilmar Alvarado-Tapias, José Alberto Ferrusquía, Sabela Lens, Antonio Guerrero, M. Àngels Falgà, Pamela Vizcarra, Lara Orts, Valeria Perez, Sarah Shalaby, Anna Baiges, Fanny Turon, Juan Carlos García-Pagán, Maria Ángeles García-Criado, Virginia Hernández-Gea
Journal: Journal of Hepatology (2024)
SAT-082 A phase 2 study of OCE-205, a novel, selective vasopressin receptor mixed agonist-antagonist: positive proof-of-concept established in subjects with cirrhosis and hepatorenal syndromeacute kidney injury (HRS-AKI)
Authors: Andrew S. Allegretti, Jasmohan Bajaj, Khurram Bari, Robert S. Brown, Giuseppe Cullaro, Daniel Ganger, Tarek Hassanein, Nyingi Kemmer, Saro Khemichian, Paul Yien Kwo, Nicholas Lim, Hasan Naqvi, Kavish Patidar, Nikolaos T. Pyrsopoulos, Robert S. Rahimi, Don Rockey, Arun J. Sanyal, Kirti Shetty, Douglas Simonetto, Lance Stein, Hugo Vargas, Philippe Zamor, David Bernstein, Lise Kjems, Jason Lam, Susan Reid, Florence Wong
Journal: Journal of Hepatology (2024)
FRI-109 Differences in the clinical phenotype of decompensated liver cirrhosis between MASLD, MetALD and ALD patients
Authors: Laura Buttler, Anja Tiede, Marie Griemsmann, Hannah Schneider, Jim Benjamin Mauz, Heiner Wedemeyer, Markus Cornberg, Tammo Lambert Tergast, Benjamin Maasoumy, Katharina Luise Hupa-Breier
Journal: Journal of Hepatology (2024)
FRI-094-YI Differential diagnosis of covert hepatic encephalopathy in a cohort of outpatients with chronic liver disease
Authors: Lyès Kheloufi, Philippe Sultanik, Apolline Leproux, Charlotte Bouzbib, Sarah Mouri, Antoine Santiago, Marika Rudler, Nicolas Weiss, Dominique Thabut. AP-HP, Brain-Liver Pitié-Salpêtrière
Journal: Journal of Hepatology (2024)
FRI-095 Privative verbal fluency test (PVFT): a quick-to-use cognitive tool for the screening of covert hepatic encephalopathy
Authors: Lyès Kheloufi, Aliyya Ahamada, Apolline Leproux, Philippe Sultanik, Sarah Mouri, Charlotte Bouzbib, Marika Rudler, Nicolas Weiss, Dominique Thabut. AP-HP, Brain-Liver Pitié-Salpêtrière
Journal: Journal of Hepatology (2024)
WED-078 Systemic albumin administration improves the gut microbiome and intestinal permeability in animal models of cirrhosis and ACLF
Authors: Alexandra Phillips, Yi Jin, Florian Rosenberger, Qianwen Zhao, Abeba Habtesion, Fausto Andreola, Nathan Davies, Frederick Clasen, Lindsey Edwards, Jane Macnaughtan, Sabine Klein, Jonel Trebicka, Saeed Shoaie, Matthias Mann, Rajiv Jalan
Journal: Journal of Hepatology (2024)
FRI-042 Comparison of clinical outcomes among patients with refractory ascites and implantation of either Alfapump, tunneled peritoneal drainage system or transjugular intrahepatic portosystemic shunt
Authors: Sarah Lisa Schutte, Anja Tiede, Jim Benjamin Mauz, Hannah Schneider, Nicolas Richter, Heiner Wedemeyer, Benjamin Maasoumy, Tammo Lambert Tergast
Journal: Journal of Hepatology (2024)
WED-110 Alterations in plasma neuronal and glial proteins in varying severities of cirrhosis and differing grades of hepatic encephalopathy
Authors: Marilena Stamouli, Christos Konstantinou, Jack Wright, Ane Zamalloa, Neil Youngson, Mark J W McPhail, Anna Hadjihambi, Vishal C Patel
Journal: Journal of Hepatology (2024)
FRI-039 Terlipressin therapy is associated with increased risk of colonization with multidrug-resistant bacteria in patients with decompensated cirrhosis
Authors: Marcus Mucke, Maria Hernandez-Tejero, Wenyi Gu, Michael Kuhn, Malte Janz, Marisa Isabell Keller, Anthony Fullam, Laura Altepeter, Victoria Mucke, Fabian Finkelmeier, Katharina Maria Schwarzkopf, Cremonese Carla, Peter Hunyady, Myriam Heilani, Frank Erhard Uschner, Robert Schierwagen, Maximilian Joseph Brol, Sabine Klein, Kai-Henrik Peiffer, Michael Hogardt, Saeed Shoaie, Minneke Coenraad, Jörg Bojunga, Vicente Arroyo, Stefan Zeuzem, Volkhard A.J. Kempf, Christoph Welsch, Wim Laleman, Peer Bork, Javier Fernandez, Jonel Trebicka
Journal: Journal of Hepatology (2024)
WED-105 Nitazoxanide directly protects from stress-induced cell death to alleviate liver damage in preclinical models of acute-on-chronic liver failure
Authors: Marie Bobowski-Gerard, Simon Debaecker, Nicolas Stankovic Valentin, Alexia Tessier, Hana Elkhatib, Philippe Delataille, Remy Hanf, Sakina Sayah Jeanne, Dean Hum, Vanessa Legry, Bart Staels
Journal: Journal of Hepatology (2024)
WED-109 Evaluation of statins as a new therapy to alleviate hepatic encephalopathy in cirrhotic mice
Authors: Subas Aroob, Qamar Niaz, Muhammad Ovais Omer, Syed Muhammad Muneeb Anjum, Ghulam Mustafa, Sania Mehreen, Muhammad Bilal Khan, Muhammad Adil Rasheed
Journal: Journal of Hepatology (2024)
WED-090 Developing a discovery platform for engineered macrophage cell therapies for end stage liver disease
Authors: Niya Aleksieva, Kayleigh Thirlwell, Philip Starkey Lewis, Mark Cant, Moony Su, Hollie Bartley, Alejandro Armesilla Diaz, Amol Ketkar, Benjamin J Dwyer, John Campbell, Stuart J Forbes, Lara Campana
Journal: Journal of Hepatology (2024)
FRI-081 Lisinopril is associated with reduced hepatocellular carcinoma and mortality risk in patients with MASLD-related compensated cirrhosis: a multicenter, nationwide propensity score matching analysis
Authors: Yee Hui Yeo, Wee Han Ng, Manal F. Abdelmalek, Seema Khan, Cynthia Moylan, Luz Rodriguez, Augusto Villanueva, Kevin Ma, Ju Dong Yang
Journal: Journal of Hepatology (2024)
WED-124 Assessment of plasma VCAM-1 levels in pediatric portal hypertension and its relationship with disease severity
Authors: Tengfei Si, Huihong Yu, Bethany Tucker, Fabiola Di Dato, Xiaohong Huang, Qing Shao, Bowen Gao, Xuan Luo, Eirini Kyrana, Yun Ma, Tassos Grammatikopoulos
Journal: Journal of Hepatology (2024)
FRI-044-YI Impact of underlying etiology of liver cirrhosis on tests for diagnosing minimal hepatic encephalopathy
Authors: Julius Egge, Alena Friederike Ehrenbauer, Maria Magdalena Gabriel, Jana Al-Ayoubi, Lea Wagner, Jennifer Witt, Jim Benjamin Mauz, Anja Tiede, Heiner Wedemeyer, Anika Grosshennig, Gerrit M. Grosse, Benjamin Maasoumy, Karin Weissenborn
Journal: Journal of Hepatology (2024)
SAT-305 Impact of corticosteroid treatment and clinical risk factors in patients with alcohol-associated hepatitis and clinically significant portal hypertension
Authors: Petra Dinjar Kujundžić, Marko Milosevic, Mislav Barišić-Jaman, David Dohoczky, Viktoria Skurla, Marta Defar, Sara Cepic, Frane Pastrovic, Ivica Grgurević
Journal: Journal of Hepatology (2024)
WED-076 Increased gut urease activity contributes to hyperammonemia and is a potential biomarker of disease severity in cirrhosis
Authors: Deepika Jakhar, Pinky Juneja, Aarti Sharma, Nishu Choudhary, Ashi Mittal, Shiv Kumar Sarin, Dinesh Mani Tripathi, Shvetank Sharma, Savneet Kaur
Journal: Journal of Hepatology (2024)
THU-083 Acute kidney injury (AKI) severity in critically-ill patients with decompensated liver cirrhosis and acute-on-chronic liver failure (ACLF)
Authors: Martin Schulz, Lena Wolters, Helen Jurr, Wenyi Gu, Maximilian Joseph Brol, Frank Erhard Uschner, Michael Tischendorf, Konrad Buscher, Alexander Zarbock, Robert Schierwagen, Sabine Klein, Stefan Zeuzem, Kai-Henrik Peiffer, Jonel Trebicka
Journal: Journal of Hepatology (2024)
LBP-042 First-in-human clinical result of a novel HBV-specific TCR T cell therapy (SCG101) in patients with HBV-related hepatocellular carcinoma (HCC)
Authors: Xueshuai Wan, Wei Wu, Yunpeng Liu, Shunda Du, Wei Li, Dongmei Quan, Ke Zhang, Karin Wisskirchen, Ulrike Protzer, Yuhong Zhou, Xiujuan Qu
Journal: Journal of Hepatology (2024)
LBP-029 Efficacy and safety of 144 weeks of bulevirtide 2 mg or 10 mg monotherapy from the ongoing phase 3 study, MYR301
Authors: Pietro Lampertico, Soo Aleman, Maurizia Brunetto, Antje Blank, Pietro Andreone, Pavel Bogomolov, Vladimir Chulanov, Nina Mamonova, Natalia Geyvandova, Viacheslav Morozov, Olga Sagalova, Tatyana Stepanova, Grace M. Chee, Dmitry Manuilov, Mingyang Li, Steve Tseng, Audrey Lau, Anu Osinusi, Julian Schulze zur Wiesch, Markus Cornberg, Stefan Zeuzem, Heiner Wedemeyer
Journal: Journal of Hepatology (2024)
THU-069 Serum bile acids determine AKI progression and terlipressin nonresponse in patients with acute-on-chronic liver failure with acute kidney injury
Authors: Rakhi Maiwall, Neha Chauhan, Ashini Hidam, Gaurav Tripathi, Sherin Sarah Thomas, Jaswinder Maras, Shiv Kumar Sarin
Journal: Journal of Hepatology (2024)
LBP-034 Evaluation of the PIKfyve kinase inhibitor Apilimod against hepatitis E virus infections
Authors: Julian Ring, Sarah Schlienkamp, Jil Haase, Xin Zhang, Johan Neyts, Suzanne J.F. Kaptein, Mara Klöhn, Daniel Todt, Yannick Brüggemann, Eike Steinmann
Journal: Journal of Hepatology (2024)
LBP-035 Luji-1 reduces fibrosis by blocking Neuroligin-4 and β-neurexin and overexpressing thyroid hormone receptor-b, suggesting Rezdiffra sensitization and synergism in combination
Authors: Johnny Amer, Ahmad Salhab, Baker Saffouri, Ashraf Imam, Abed Khalaileh, Rifaat Safadi
Journal: Journal of Hepatology (2024)
THU-053 Longitudinal salivary metagenomics in acute-on-chronic liver failure patients
Authors: Manolo Laiola, Maria Papp, Wenyi Gu, Nathalie Galleron, Benoit Quinquis, Mamadou-Gabou Thiam, Emmanuelle Le Chatelier, Hervé Blottière, S. Dusko Ehrlich, Mathieu Almeida, Jonel Trebicka
Journal: Journal of Hepatology (2024)
OS-063 What happens to HCV incidence after WHO elimination goal is met? Agent-based modeling predicts sustained availability of direct-acting antivirals among people who inject drugs is required to prevent returning to pre-elimination levels
Authors: Eric Tatara, Louis Shekhtman, Nicholson Collier, Marian Major, Jonathan Ozik, Basmattee Boodram, Harel Dahari
Journal: Journal of Hepatology (2024)
OS-061 Chronic hepatitis C virus infection induces HCC risk by perturbing the human liver circadian transcriptome and epigenome through deregulation of the deacetylase SIRT1
Authors: Atish Mukherji, Frank Jühling, Yogy Simanjuntak, Michio Imamura, Emilie Crouchet, Fabio Del Zompo, Yuji Teraoka, Alexandre Haller, Philippe Baltzinger, Soumith Paritala, Fahmida Rasha, Naoto Fujiwara, Cloé Gadenne, Nevena Slovic, Marine Oudot, Sarah Durand, Clara Ponsolles, Catherine Schuster, Xiaodong Zhuang, Jacinta Holmes, Ming-Lun Yeh, Hiromi Abe-Chayama, Mathias Heikenwälder, Angelo Sangiovanni, Massimo Iavarone, Massimo Colombo, Jane McKeating, Irwin Davidson, Ming-Lung Yu, Raymond Chung, Yujin Hoshida, Kazuaki Chayama, Joachim Lupberger, Thomas Baumert
Journal: Journal of Hepatology (2024)
LBP-021 BRII-179 induced functional immune response, demonstrating potential to improve chronic hepatitis B functional cure
Authors: Zhiliang Gao, Libo Yan, Jianping Li, Rong Hu, Peng Hu, Wei Yue, Fangfang Lv, Yiwen Liu, Chunming Li, Yue Wu, Weihong Liu, Xiaofei Chen, Qing Zhu
Journal: Journal of Hepatology (2024)
OS-096-YI Spleen stiffness measurement by transient elastography at 100 Hz refines the non-invasive diagnosis of clinically significant portal hypertension in compensated advanced chronic liver diseasefinal results of a european multicenter study
Authors: Mathias Jachs, Lucile Moga, Wilhelmus J Kwanten, Petra Fischer, Aitor Odriozola, Fanny Turon, Dario Saltini, Luis Téllez, Angelo Armandi, Yuly Mendoza, Elba Llop Herrera, Maria Grasso, Elton Dajti, Emma Vanderschueren, Lisa Sandmann, Julia Thalhammer, Carlos Pardo, Lotte Schoenmakers, Thomas Vanwolleghem, Luisa Vonghia, Christian Labenz, Georg Semmler, Lukas Hartl, Benjamin Maasoumy, Wim Laleman, Federico Ravaioli, José Presa, Vincenza Calvaruso, José Luis Calleja Panero, Annalisa Berzigotti, Jörn M Schattenberg, Agustín Albillos, Antonio Colecchia, Filippo Schepis, Juan Carlos García-Pagán, Angela Puente, Jose Ignacio Fortea, Bogdan Procopet, Sven Francque, Pierre-Emmanuel Rautou, Thomas Reiberger, Mattias Mandorfer
Journal: Journal of Hepatology (2024)
OS-086-YI Protein tyrosine phosphatase non-receptor type 2 controls hepatic function of cytotoxic T cells in metabolic dysfunction-associated steatohepatitis
Authors: Madita Determann, Luise Linzmeier, Marlene Schwarzfischer, Anna Niechcial, Marianne Rebecca Spalinger, Yasser Morsy, Doris Pöhlmann, Marijn Wilmink, Maria Walker, Federica Sella, Mitchell Levesque, Viktor Hendrik Koelzer, Anja Laura Frei, Stephan Buch, Jochen Hampe, Christian Datz, Clemens Schafmayer, Mathias Heikenwälder, Michael Scharl, Sena Blümel
Journal: Journal of Hepatology (2024)
OS-041-YI A spatiotemporal map of the hepatocyte proteome in alpha-1 antitrypsin deficiency by single-cell and visual proteomics
Authors: Florian Rosenberger, Katrine Thorhauge, Sophia Mädler, Malin Fromme, Caroline Weiss, Marc Oeller, Sophia Steigerwald, Marvin Thielert, Thierry Nordmann, Sönke Detlefsen, Peter Boor, Ondřej Fabián, Soňa Fraňková, Aleksander Krag, Pavel Strnad, Matthias Mann
Journal: Journal of Hepatology (2024)
OS-062 Long-term liver morbidity and mortality after HCVelimination by direct-acting antivirals in patients with chronic hepatitis C: results from a large-scale, multicenter cohort study
Authors: Eiichi Ogawa, Akira Kawano, Motoyuki Kohjima, Toshimasa Koyanagi, Kazufumi Dohmen, Aritsune Ooho, Takeaki Satoh, Kazuhiro Takahashi, Norihiro Furusyo, Eiji Kajiwara, Koichi Azuma, Yasunori Ichiki, Rie Sugimoto, Hiromasa Amagase, Takeshi Senju, Chie Morita, Masatake Tanaka, Makoto Nakamuta, Hideyuki Nomura, Jun Hayashi
Journal: Journal of Hepatology (2024)
OS-093 Efficient and heritable elimination of HBV viral antigens in vivo by epigenome editing
Authors: Wenbo Peng, Junzheng Zhao, Dai-tze Wu, Shaoshuai Mao, Leilei Wu, Jing Sun, Ruimin Lv, Di Sun, Bob Zhang, YiDi Sun, Changyang Zhou
Journal: Journal of Hepatology (2024)