tbuckley/cabot-search huggingface dataset:
Cost-Effectiveness of Home-Based Screening for Albuminuria in the General Population in the Netherlands
Authors: Dominique van Mil, Xavier G. Pouwels, Lyanne M. Kieneker, Ronald W. van Etten, Birgitte M. Evers-Roeten, Marc Thelen, Marc H. Hemmelder, Ron T. Gansevoort, Hendrik Koffijberg
Journal: Journal of the American Society of Nephrology (2023)
Effects of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors on Copper Metabolism and Association with Organ Damage in CKD
Authors: Tomofumi Moriyama, Kensei Taguchi, Goh Kodama, Kei Fukami
Journal: Journal of the American Society of Nephrology (2023)

Division of Nephrology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.
Atypical Hemolytic Uremic Syndrome (aHUS) Clinical Characteristics Associated with Renal Replacement Therapy (RRT) Initiation During Index Hospitalization and RRT Requirement After Discharge
Authors: Stephen W. Olson, Briana C. Ndife, Jennifer Nguyen, Elizabeth Nagelhout, Colette Ndiba-Markey, Swastina Shrestha
Journal: Journal of the American Society of Nephrology (2023)
Red Blood Cell Distribution Width-Coefficient of Variation as an Indicator of the Requirement for and Efficacy of Daprodustat in Hemodialysis Patients Switching from Erythropoietin-Stimulating Agents
Authors: Kenichi Morii, Toshiki Doi, Yoshiko Nishizawa, Kazuomi Yamashita, Kenichiro Shigemoto, Sonoo Mizuiri, Takao Masaki
Journal: Journal of the American Society of Nephrology (2023)
Advanced Disease Modeling of the Fabry Disease Cardiorenal Phenotype with Organoids from Patient-Derived Human-Induced Pluripotent Stem Cells
Authors: Anna Reinelt, Sandra D. Laufer, Milagros N. Wong, Fabian Haas, Luise Foerster, Linda Blomberg, Christine E. Kurschat, Nicola Wanner, Victor G. Puelles, Arne Hansen, Tobias B. Huber, Fabian Braun
Journal: Journal of the American Society of Nephrology (2023)
Association Between Reduced RAASi Therapy and Progression to ESKD in Hyperkalemic CKD Patients
Authors: Anjay Rastogi, Charles Pollack, Eva Lesén, Abiy Agiro, Matthew Arnold, Naru Morita, Krister Järbrink, Toyoaki Murohara, Eiichiro Kanda
Journal: Journal of the American Society of Nephrology (2023)
Micral-Test® Strip to Detect Albuminuria Among Patients with CKD Risk Factors
Authors: Xi Yan Ooi, Wanting Weng, See Cheng Yeo
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 367-368, November 2023. | DOI: 10.1681/ASN.20233411S1367d
CCL18-PITPNM3 Mediates Macrophage-Mesothelial Cross-Talk and Promotes Peritoneal Dialysis-Associated Peritoneal Fibrosis
Authors: Yuxiang Sun, Qiang Huang, Hui Peng
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 915, November 2023. | DOI: 10.1681/ASN.20233411S1915b
Arginine Vasopressin Deficiency in the Hypoxic Brain
Authors: Leanna V. Ritchie, Abdul Basit, Lyle W. Baker
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 926-927, November 2023. | DOI: 10.1681/ASN.20233411S1926e
Renal Riddles: Acute Interstitial Nephritis in Newly Diagnosed HIV
Authors: Amulya Rajagopal, Ruchi J. Sahota, James Hanna, Vivek Soi, Mark D. Faber, Lalathaksha Murthy Kumbar
Journal: Journal of the American Society of Nephrology (2023)

Rajagopal, Amulya; Sahota, Ruchi J.; Hanna, James; Soi, Vivek; Faber, Mark D.; Kumbar, Lalathaksha Murthy Author Information
HIV-1 Protein Nef Acts in Synergy with APOL1-G1 to Impair Nephrocyte Function by Inhibiting Autophagy and Endocytosis Pathway
Authors: Junyi Zhu
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 948-949, November 2023. | DOI: 10.1681/ASN.20233411S1948c
The Effect of Sodium-Glucose Cotransporter 2 Inhibitors on Hemoglobin Levels in Patients with CKD
Authors: Carmen E. Cervantes, Tareq Hanouneh, Veena K. Acharya, Jonathan G. Lim, Hyung M. Lim, Mohamad A. Hanouneh
Journal: Journal of the American Society of Nephrology (2023)
Phenotypic Quantification of an Hnf1b Knockout Mouse Model
Authors: Selina Hölzel, Caroline M. Kolvenbach, Florian Buerger, Katharina Lemberg, Ken Saida, Seyoung Yu, Daanya Salmanullah, Bshara Mansour, Izzeldin Elmubarak, Nils D. Mertens, Shirlee Shril, Friedhelm Hildebrandt
Journal: Journal of the American Society of Nephrology (2023)

Hölzel, Selina; Kolvenbach, Caroline M.; Buerger, Florian; Lemberg, Katharina; Saida, Ken; Yu, Seyoung; Salmanullah, Daanya; Mansour, Bshara; Elmubarak, Izzeldin; Mertens, Nils D.; Shril, Shirlee; Hildebrandt, Friedhelm Author Information
Kynurenine 3-Monooxygenase Limits De Novo NAD+ Synthesis Through Dietary Tryptophan in Cultured Renal Proximal Tubule Epithelial Cells
Authors: Yougang Zhai, Rong Meng, Jose A. Chavez, Andrea R. Nawrocki, Alessandro Pocai, Lifeng Wang, Li-Jun Ma
Journal: Journal of the American Society of Nephrology (2023)

Zhai, Yougang; Meng, Rong; Chavez, Jose A.; Nawrocki, Andrea R.; Pocai, Alessandro; Wang, Lifeng; Ma, Li-Jun; CVMR-PH Discovery Janssen Research & Development LLC.; CVMR-PH Discovery Janssen Research & Development LLC. Author Information
Instantaneous and Persistent Elevation of Serum Potassium and Progression of CKD
Authors: Jinwei Wang, Fang Wang, Ming-Hui Zhao
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 380, November 2023. | DOI: 10.1681/ASN.20233411S1380b
Injection of Silicone for Cosmetic Gluteal Augmentation Leading to Hypercalcemia
Authors: Anita Kamarzarian, Masoud Haghi, Phuong-Chi T. Pham, Golriz Jafari
Journal: Journal of the American Society of Nephrology (2023)

Kamarzarian, Anita; Haghi, Masoud; Pham, Phuong-Chi T.; Jafari, Golriz Author Information
CKD of Unknown Origin (CKDu) Is Associated with Subclinical Rhabdomyolysis
Authors: Magdalena Madero, Richard J. Johnson, Catharina Wesseling, Ana K. Fernandez Yepez, L. Gabriela Sanchez-Lozada, Jason R. Glaser, Ilana Weiss, Bernardo Rodriguez-Iturbe
Journal: Journal of the American Society of Nephrology (2023)
Refractory Hypercalcemia: Unmasking Pneumocystis jirovecii Pneumonia in a Renal Transplant Recipient
Authors: Wern Lynn Ng, Lillian Sangha, Benjamin Ravichander, Evelyn J. Calderon Martinez, Lay She Ng, Gabriela M. Calderon Barahona, Jia Yi Tan, Seema Sharma Gautam, Irina Mishagina
Journal: Journal of the American Society of Nephrology (2023)
Use of Copeptin to Diagnose Nephrogenic Diabetes Insipidus Secondary to Hypercalcemia
Authors: Olivia R. Drummond, Adrian J. Baudy
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 933, November 2023. | DOI: 10.1681/ASN.20233411S1933a
Differential Regulation of MYC Expression by PKHD1/Pkhd1 in Human and Mouse Kidneys: Phenotypic Implications for Recessive Polycystic Kidney Disease
Authors: Naoe Harafuji, Chaozhe Yang, Ljubica Caldovic, Girija Thiruvengadam, Heather Gordish-Dressman, Robert G. Thompson, Phillip D. Bell, Avi Z. Rosenberg, Zsuzsanna M. Bebok, Lisa M. Guay-Woodford
Journal: Journal of the American Society of Nephrology (2023)
An Unusual Case of Hypercalcemia
Authors: James Flatow, Mariana A. Chang, Farid Arman, Pedro D. Mogrovejo Pintado, Qais Al-Awqati
Journal: Journal of the American Society of Nephrology (2023)

Flatow, James; Chang, Mariana A.; Arman, Farid; Pintado, Pedro D. Mogrovejo; Al-Awqati, Qais Author Information
CFTR Modulators Mitigate Autosomal Recessive Polycystic Kidney Disease
Authors: Cristian Ciobanu, Liudmila Cebotaru
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 945, November 2023. | DOI: 10.1681/ASN.20233411S1945c
International Comparison of Home Dialysis Uptake: A Multi-Registry Analysis from the INTEGRATED Research Group
Authors: Annabel Boyer, Isabelle Ethier, David W. Johnson, Eric D. Weinhandl, Karthik K. Tennankore, Thierry Lobbedez, Clémence Béchade, Naoual Elftouh, Mark Lambie, Annie-Claire Nadeau-Fredette
Journal: Journal of the American Society of Nephrology (2023)
Do Protein Intake, Serum Bicarbonate, and Inflammatory Markers Explain the Associations of Advanced CKD with Muscle Wasting?
Authors: Farahnaz Akrami, Ravinder Singh, Robert E. Boucher, Guo Wei, Augustine Takyi, Azeem M. Mohammed, Amara Sarwal, Sydney E. Hartsell, George Bissada, Srinivasan Beddhu
Journal: Journal of the American Society of Nephrology (2023)

Akrami, Farahnaz; Singh, Ravinder; Boucher, Robert E.; Wei, Guo; Takyi, Augustine; Mohammed, Azeem M.; Sarwal, Amara; Hartsell, Sydney E.; Bissada, George; Beddhu, Srinivasan Author Information
Automated 3D Cortical Thickness Measurements from CT Images: A Novel Predictor of Low Kidney Function in Living Kidney Donors
Authors: Timothy L. Kline, Adriana Gregory, Panagiotis Korfiatis, Andrew D. Rule, Aleksandar Denic
Journal: Journal of the American Society of Nephrology (2023)

Kline, Timothy L.; Gregory, Adriana; Korfiatis, Panagiotis; Rule, Andrew D.; Denic, Aleksandar Author Information
The Pkhd1del3-67 Deletion Disrupts Local Genomic Architecture Resulting in Reduced Expression of Tfap-2b in the Developing Eye and Peters Anomaly
Authors: Yu Ishimoto, Naoki Nakaya, Karla Y. Barbosa Sabanero, Fang Zhou, Laura Kerosuo, Stanislav I. Tomarev, Luis F. Menezes, Gregory G. Germino
Journal: Journal of the American Society of Nephrology (2023)

Ishimoto, Yu; Nakaya, Naoki; Sabanero, Karla Y. Barbosa; Zhou, Fang; Kerosuo, Laura; Tomarev, Stanislav I.; Menezes, Luis F.; Germino, Gregory G. Author Information
Modified Formula to Predict a Change in Serum Sodium in Patient with Hyponatremia Requiring RRT
Authors: Shruti Shettigar, Scott D. Cohen, Shane A. Bobart, Surafel K. Gebreselassie
Journal: Journal of the American Society of Nephrology (2023)

Shettigar, Shruti; Cohen, Scott D.; Bobart, Shane A.; Gebreselassie, Surafel K. Author Information
Serum Osmolality Testing and Preserved GFR Are Associated with Improved 30-Day Mortality in Severely Hyponatremic Patients
Authors: Oliver J. Fox, Cai Davis, Thomas Ash, Kristin Veighey
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 932, November 2023. | DOI: 10.1681/ASN.20233411S1932a
Ketogenic Diet Mitigates Renal Fibrosis and Partially Preserves Kidney Function in Nephrotoxic Serum Nephritis
Authors: Konstantin A. Kloetzer, Max Schuller, Marcell Krall, Katharina Artinger, Corinna Schabhüttl, Agnes A. Mooslechner, Hansjörg Habisch, Tobias Madl, Alexander R. Rosenkranz, Philipp Eller, Kathrin Eller
Journal: Journal of the American Society of Nephrology (2023)

Kloetzer, Konstantin A.; Schuller, Max; Krall, Marcell; Artinger, Katharina; Schabhüttl, Corinna; Mooslechner, Agnes A.; Habisch, Hansjörg; Madl, Tobias; Rosenkranz, Alexander R.; Eller, Philipp; Eller, Kathrin Author Information
Dietary Acid Reduction with Either Fruits and Vegetables or Oral NaHCO3, Adjuvant to Angiotensin-Converting Enzyme Inhibition, Slows Progression of Macroalbuminuric Stage G1 CKD
Authors: Nimrit Goraya, Jan Simoni, Maninder Kahlon, Nazan Aksan, Donald E. Wesson
Journal: Journal of the American Society of Nephrology (2023)
Is the Cost of the New Home Dialysis Techniques Still Advantageous Compared to In-Centre Hemodialysis?
Authors: Dario Roccatello, Roberta Fenoglio, Savino Sciascia
Journal: Journal of the American Society of Nephrology (2023)

University Center of Excellence on Nephrologic, Rheumatologic and Rare Diseases, Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley, San Giovanni Bosco Hub Hospital, University of Turin, Turin, Italy.
Evaluating the Outcomes of Roxadustat Treatment for Anemia in Dialysis-Dependent CKD: A Systematic Review and Meta-Analysis
Authors: Muhammed Khaled Elhadi Elfaituri, Taha K. Elfaituri, Hazem Faraj, Ahmed Msherghi
Journal: Journal of the American Society of Nephrology (2023)

Elfaituri, Muhammed Khaled Elhadi; Elfaituri, Taha K.; Faraj, Hazem; Msherghi, Ahmed Author Information
Case Report on Successful Treatment of Life-Threatening Anemia in ESRD Patient on Maintenance Hemodialysis Who Is a Jehovah Witness and Refusing Blood Transfusion
Authors: Omar N. Elhawary, Sandeep R. Sasidharan, Syeda S. Bukhari, Isha Puri, Mary C. Mallappallil
Journal: Journal of the American Society of Nephrology (2023)
Comparison Between Longitudinal Kidney Function and Volume Changes in Association with Heart Failure Outcomes Among Discharged Patients in EVEREST
Authors: Tatsufumi Oka, Hocine Tighiouart, Wendy I. McCallum, Marcelle Tuttle, Marvin Konstam, James Udelson, Mark J. Sarnak
Journal: Journal of the American Society of Nephrology (2023)

Oka, Tatsufumi; Tighiouart, Hocine; McCallum, Wendy I.; Tuttle, Marcelle; Konstam, Marvin; Udelson, James; Sarnak, Mark J. Author Information
Impaired Sodium Dipping Is Associated with Poor Blood Pressure Control in Patients on Peritoneal Dialysis
Authors: Washington A. Freire Filho, Ana Teresa P. Vieira, Edilene Maria dos Santos, Luiza K. Araujo, Benedito J. Pereira, Hugo Abensur, Zita M. Britto, Rosilene M. Elias
Journal: Journal of the American Society of Nephrology (2023)

Filho, Washington A. Freire; Vieira, Ana Teresa P.; dos Santos, Edilene Maria; Araujo, Luiza K.; Pereira, Benedito J.; Abensur, Hugo; Britto, Zita M.; Elias, Rosilene M. Author Information
Rapid Nephrogenomics in Intensive Care for Early Intervention in Adult Thrombotic Microangiopathies
Authors: Nadhir Yousfi, Marie Mille, Abderaouf Hamza, Sophie Vandermeersch, Sacha Beaumeunier, Denis Bertrand, Michael Blum, Julien Doudement, Carine El Sissy, Paula Vieira-Martins, Nicolas Philippe, Veronique Fremeaux Bacchi, Laurent Mesnard
Journal: Journal of the American Society of Nephrology (2023)
Febuxostat vs. Allopurinol in CKD Patients: Observational Study on Cardiovascular Events and Deaths
Authors: Miho Otani, Sae Shinomiya, Yasutaka Ihara, Ryota Kawai, Hisako Yoshida, Kazuhiko Tsuruya, Ayumi Shintani
Journal: Journal of the American Society of Nephrology (2023)
Low vs. Standard Starting Dose Oral Roxadustat for Treating Anemia in Chinese Patients with CKD on Dialysis: A Prospective, Randomized Clinical Trial
Authors: Bi-Cheng Liu, Yan Tu, Yan Xu, Li Yao, Bei ru Zhang, Tiekun Yan, Aiping Yin, Xinzhou Zhang, Min Yang, Jun Liu, Caili Wang, Xiaomei Peng, Wang Jianqin, Wei Niu, Wenqing Jiang
Journal: Journal of the American Society of Nephrology (2023)
Roxadustat vs. Erythropoiesis in the Nephroprotection Treatment of Patients with CKD and Anemia
Authors: Yan Ouyang, Hong Ren, Jingyuan Xie, Xiaocen Fu, Xiao Li, Weiming Wang, Nan Chen
Journal: Journal of the American Society of Nephrology (2023)

Ouyang, Yan; Ren, Hong; Xie, Jingyuan; Fu, Xiaocen; Li, Xiao; Wang, Weiming; Chen, Nan Author Information
Effect of ESRD Prospective Payment System on Utilization of Peritoneal Dialysis in Patients with Kidney Allograft Failure
Authors: Ali I. Gardezi, Zhongyu Yuan, Fahad Aziz, Sandesh Parajuli, Didier A. Mandelbrot, Micah R. Chan, Brad C. Astor
Journal: Journal of the American Society of Nephrology (2023)

Gardezi, Ali I.; Yuan, Zhongyu; Aziz, Fahad; Parajuli, Sandesh; Mandelbrot, Didier A.; Chan, Micah R.; Astor, Brad C. Author Information
Prevalence of APOL1 Variants in Persons with Proteinuric CKD
Authors: Kate Bramham, Bertrand Knebelmann, Vincent Audard, Jean-Jacques Boffa, Diego Echeverri, Kieran Mccafferty, Thomas Powell, Christopher Provenzano, Nauman Shahid, Mohamad Zaidan, Pablo A. Urena Torres, Gianna Mastroianni-Kirsztajn, Aurelia Zamauskaite, Irisz K. Delestre-Levai, John Bauman, Yuan Yang, Silva Krause, Anna Ferreira, Ogo I. Egbuna, Glenn Chertow
Journal: Journal of the American Society of Nephrology (2023)
Diagnostic Dilemma of a Case of Complex Refractory Hypomagnesemia
Authors: Osama Elhilali, Irtiza Hasan, Charles W. Heilig
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 923, November 2023. | DOI: 10.1681/ASN.20233411S1923b
Kidney Allograft Outcomes Are Similar in Recipients with Living Donors with Hematuria Compared with Recipients with Living Donors Without Hematuria
Authors: Tripti Singh, Krista Brackman, Brad C. Astor, Didier A. Mandelbrot
Journal: Journal of the American Society of Nephrology (2023)

Singh, Tripti; Brackman, Krista; Astor, Brad C.; Mandelbrot, Didier A. Author Information
First Detection of Microplastics Fragments in Human Urine and Kidney Tissues
Authors: Sara Massardo, Edoardo La Porta, Enrico E. Verrina, Francesca Lugani, Stefano Alberti, Claudia Caboni, Matteo Santostefano, Daniela Verzola, Pasquale Esposito, Gianluigi Zaza, Cristina Artini
Journal: Journal of the American Society of Nephrology (2023)
Calcium- and Iron-Based Phosphate Binders Impact the Gut Microbiome in Rats with CKD
Authors: Annabel Biruete, Shruthi Srinivasan, Kalisha O’Neill, Henriette De loor, Pieter Evenepoel, Kelly Swanson, Neal X. Chen, Sharon M. Moe
Journal: Journal of the American Society of Nephrology (2023)
APOL1 Risk Variants Induce Mitochondrial Dysfunction in Patient-Derived Kidney Organoids
Authors: Heein Song, Sébastien J. Dumas, Lijun Ma, Gangqi Wang, Franca Witjas, Cathelijne W. Van den Berg, Michael V. Rocco, Barry I. Freedman, Ton J. Rabelink, Siebe Spijker
Journal: Journal of the American Society of Nephrology (2023)
Males Show Greater eGFR Recovery than Females Following Kidney Donation
Authors: Austin M. Hilvert, Jared V. Grice, Trey W. Mcgonigle, Shi Huang, Niketna Vivek, Hamideh Ale Ali, Beatrice P. Concepcion, Anthony J. Langone, Heidi M. Schaefer, Rachel C. Forbes
Journal: Journal of the American Society of Nephrology (2023)

Hilvert, Austin M.; Grice, Jared V.; Mcgonigle, Trey W.; Huang, Shi; Vivek, Niketna; Ali, Hamideh Ale; Concepcion, Beatrice P.; Langone, Anthony J.; Schaefer, Heidi M.; Forbes, Rachel C. Author Information
Fewer Communities Left Behind: Peritoneal Dialysis (PD) Initiation Patterns by Health Service Area in an Era of Expansion
Authors: Christopher D. Knapp, Shuling Li, Chuanyu Kou, Eric D. Weinhandl, David T. Gilbertson, James B. Wetmore, Allyson Hart, Kirsten L. Johansen
Journal: Journal of the American Society of Nephrology (2023)
An Unusual Case of Lupus-Associated Atypical Hemolytic Uremic Syndrome Presenting with Diffuse Alveolar Hemorrhage and Acute Renal Failure
Authors: Andrea Theodoru
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 951, November 2023. | DOI: 10.1681/ASN.20233411S1951b
Impact of Suspensions and Reactivations from Waitlist on Quality of Life in Canadian-Australasian Randomised Trial of Screening Kidney Transplant Candidates for Coronary Artery Disease (CARSK)
Authors: Karan K. Shah, Kristy Robledo, Bree Shi, John S. Gill, Tracey Ying, Melanie Wyld, Rachael L. Morton
Journal: Journal of the American Society of Nephrology (2023)
Outcomes of Foam Sclerotherapy for Large Kidney/Liver Cysts using Multi-Stage (Same/Next Day) and Multiple Sequential Procedures
Authors: Cassie Howe, Ryan Helland, Adriana Gregory, Timothy L. Kline, Lisa E. Vaughan, Vicente E. Torres, Marie C. Hogan
Journal: Journal of the American Society of Nephrology (2023)

Howe, Cassie; Helland, Ryan; Gregory, Adriana; Kline, Timothy L.; Vaughan, Lisa E.; Torres, Vicente E.; Hogan, Marie C. Author Information
Functional TRPV4 Status Sets the Rate of Cytogenesis in Autosomal Recessive Polycystic Kidney Disease (ARPKD) During Variations in Dietary Potassium
Authors: Kyrylo Pyrshev, Anna Stavniichuk, Mariya Kordysh, Oleg L. Zaika, Oleh Pochynyuk
Journal: Journal of the American Society of Nephrology (2023)

Pyrshev, Kyrylo; Stavniichuk, Anna; Kordysh, Mariya; Zaika, Oleg L.; Pochynyuk, Oleh Author Information
The Clinicopathologic and Genetic Characteristics of Autosomal Recessive Polycystic Kidney Disease Presenting in Adulthood
Authors: Elhussein A. Elhassan, Sahin Sarihan, Susan M. McAnallen, Orla Marie Dunne, Katherine A. Benson, Gianpiero Cavalleri, Peter J. Conlon
Journal: Journal of the American Society of Nephrology (2023)
From Shock to Sprinklers: A Rare Case of Polyuria in the ICU
Authors: Juan P. Moreno-Ortiz, Hiba Hamdan, Dana Sheely, Shubha Ananthakrishnan
Journal: Journal of the American Society of Nephrology (2023)

Moreno-Ortiz, Juan P.; Hamdan, Hiba; Sheely, Dana; Ananthakrishnan, Shubha Author Information
Association of Co-Exposure to Cadmium and Lead with CKD and Cardiovascular Disease (CVD) Comorbidity in US Adults: NHANES 2003-2018
Authors: Meda E. Pavkov, Michael D. Lewin, Babatunde Y. Alli, Anne L. Sowell, Youn K. Shim
Journal: Journal of the American Society of Nephrology (2023)
APOL1-Inflammation and Hypoxia Axis in Ischemic Donor Kidneys
Authors: Yasar Caliskan, Kento Kurashima, Meghan M. Unes, Edward L. Portz, Fadee Abu Al Rub, David S. Brink, Mustafa Nazzal, Ajay Jain, Krista L. Lentine, John C. Edwards
Journal: Journal of the American Society of Nephrology (2023)

Caliskan, Yasar; Kurashima, Kento; Unes, Meghan M.; Portz, Edward L.; Rub, Fadee Abu Al; Brink, David S.; Nazzal, Mustafa; Jain, Ajay; Lentine, Krista L.; Edwards, John C. Author Information
Efficiency and Efficacy of Anemia Therapy with Epoetin Beta: Results from a Randomized Controlled Trial of Therapy Software vs. Standard of Care
Authors: David J. Joerg, Doris H. Fuertinger, Kevin Ho, Lin-Chun Wang, Lela Tisdale, Xiaoling Ye, Stephan Thijssen, Peter Kotanko
Journal: Journal of the American Society of Nephrology (2023)
Gitelman-Like Syndrome Associated with Seizure Secondary to Chronic Proton Pump Inhibitor Use and Alcohol Consumption: Case Report of Undetectable Magnesium
Authors: Sergio P. de Souza, Isadora G. Dultra, Ludmila B. Santos, Maiara V. Requião, Marcel M. Gomes, Marcelo Lopes, Luis M. Conceição, Fernanda O. Coelho, Paulo benigno P. Batista, Rogerio Passos, Marcelo D. Silveira
Journal: Journal of the American Society of Nephrology (2023)

de Souza, Sergio P.; Dultra, Isadora G.; Santos, Ludmila B.; Requião, Maiara V.; Gomes, Marcel M.; Lopes, Marcelo; Conceição, Luis M.; Coelho, Fernanda O.; Batista, Paulo benigno P.; Passos, Rogerio; Silveira, Marcelo D. Author Information
Semi-synthetic chondroitin sulfate CS-semi5 upregulates miR-122-5p, conferring a therapeutic effect on osteoarthritis via the p38/MMP13 pathway
Authors: Xiang Li, Ya Zhou, Xuefeng Chen, Hongjun Wang, Shuang Yang, Jun Yang, Yunfeng Song, Zhehui Zhao, Haijing Zhang, Lianqiu Wu
Journal: Acta Pharmaceutica Sinica B (2024)

Osteoarthritis (OA) is an aging-associated disease characterized by joint stiffness pain and destroyed articular cartilage. Traditional treatments for OA are limited to alleviating various OA symptoms. There is a lack of drugs available in clinical practice that can truly repair cartilage damage. Here, we developed the chondroitin sulfate analog CS-semi5, semi-synthesized from chondroitin sulfate A. In vivo, CS-semi5 alleviated inflammation, provided analgesic effects, and protected cartilage in the modified Hulth OA rat model and papain-induced OA rat model. A bioinformatics analysis was performed on samples from OA patients and an exosome analysis on papain-induced OA rats, revealing miR-122-5p as the key regulator associated with CS-semi5 in OA treatment. Binding prediction revealed that miR-122-5p acted on the 3′-untranslated region of p38 mitogen-activated protein kinase, which was related to MMP13 regulation. Subsequent in vitro experiments revealed that CS-semi5 effectively reduced cartilage degeneration and maintained matrix homeostasis by inhibiting matrix breakdown through the miR-122-5p/p38/MMP13 axis, which was further validated in the articular cartilage of OA rats. This is the first study to investigate the semi-synthesized chondroitin sulfate CS-semi5, revealing its cartilage-protecting, anti-inflammatory, and analgesic properties that show promising therapeutic effects in OA via the miR-122-5p/p38/MMP13 pathway.
Overcorrection in the Management of Hyponatremic Patients [Na+] ≤125 mmol/L Following Emergency Department Admission
Authors: Shruti Kore, George N. Coritsidis, Sanjeev Gupta, James Beck
Journal: Journal of the American Society of Nephrology (2023)

Journal of the American Society of Nephrology 34(11S):p 932, November 2023. | DOI: 10.1681/ASN.20233411S1932c