CARCINOMA OF THE ISLANDS OF LANGERHANS WITH LIVER METASTASIS PRODUCING HYPERINSULINISM
Authors: J. S. Browning
Journal: Annals of Internal Medicine (1943)

Case Reports1 October 1943CARCINOMA OF THE ISLANDS OF LANGERHANS WITH LIVER METASTASIS PRODUCING HYPERINSULINISMJ. S. BROWNING, M.D.J. S. BROWNING, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-19-4-669 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis case is being reported because of the apparent rarity of the condition and the fairly typical clinical course exhibited. A review of the literature up to the time this paper was written revealed only 131similar cases reported in man, seven of which had either lymph node or liver metastasis or both. This patient presented the usual clinical picture associated with hyperinsulinism.2It is to be regretted that a biological assay for insulin was not made of the metastatic nodules in the liver, as has been shown by Powers and Wilder to be conclusive proof of the origin of...Bibliography1. WILDERALLANPOWERROBERTSON RMFNMHHE: Carcinoma of the islands of the pancreas; hyperinsulinism and hypoglycemia, Jr. Am. Med. Assoc., 1927, xxcix, 348-355. THALHIMER, WM., and MURPHY, F. D.: Carcinoma of the islands of the pancreas; hyperinsulinism and hypoglycemia, Jr. Am. Med. Assoc., 1928, xci, 89-91. HOWLAND, G., CAMPBELL, W. R., MALTBY, E. J., and ROBINSON, W. L.: Dysinsulinism, Jr. Am. Med. Assoc., 1929, xciii, 674-679. HAMDI, H.: Ein insulargenetisches Pankreascarcinom (Insulom), Ztschr. f. Krebsforsch., 1932, xxxvii, 411-413. CALLALORDA, J., ESCARRAS: Epithelioma of Islands of Langerhans, Lyon chir., 1933, xxx, 248-253. JUDD, E. S., FAUST, L. S., and DIXON, R. K.: Carcinoma of the islands of Langerhans with metastasis to the liver producing hyperinsulinism, West Jr. Surg., 1934, xl, 555-557. BICKEL, G., MOZER, J. J., and JUNET, R.: Diabete avec dénutrition grave: Disparition de la glycosurie et atténuation progressive de l'hyperglycemie à la suite du développement d'un carcinome insularie du pancréas avec métastases hépatiques massives, Bull. et mém. Soc. méd. d. hôp. de Paris, 1935, li, 12-21. EVANGELISTI, T.: Cancer with cells of islet type, carcinoma of endocrine type, Policlinico (sez. chir.), 1935, xlii, 384-403. CRAGG, R. W., POWER, M. H., and LINDEN, M. C.: Carcinoma of the islands of Langerhans with hypoglycemia and hyperinsulinism, Arch. Int. Med., 1937, lx, 88-99. JOACHIM, H., and BANOWITCH, M. M.: A case of carcinoma of the islands of Langerhans with hypoglycemia, ANN. INT. MED., 1938, xi, 1754-1759. ISAJI, M.: Uber Inselzelladenome und Inselzellcarcinome der Bauchspeicheldrüse, Frankfurter Ztschr. f. Path., 1939, liii, 178-207. FLINN, LEWIS B., BEATTY, G. A., GINSBERG, MILTON, and HEMSATH, F. A.: Carcinoma of the Islands of Langerhans, Jr. Am. Med. Assoc., 1941, cxvii, 283-285. BALLINGER, JOSEPH: Hypoglycemia from metastasizing insular carcinoma of aberrant pancreatic tissue in the liver, Arch. Path., 1941, xxxii, 277-285. CrossrefGoogle Scholar2. HARRIS S: Hyperinsulinism and dysinsulinism, Jr. Am. Med. Assoc., 1924, xxciii, 729-733. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Indianapolis, Indiana*Received for publication December 22, 1941. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGiant InsulinomaMetastasizing insulinoma with hypoglycæmiaINSULOMASCarcinoma of the Islets of Langerhans with Hyperinsulinism 1 October 1943Volume 19, Issue 4Page: 669-673KeywordsHospital medicineHyperinsulinemiaInsulinLiverLymph nodesPathologists ePublished: 1 December 2008 Issue Published: 1 October 1943 PDF downloadLoading ...