tbuckley/cabot-search huggingface dataset:
Evaluation of transrectal ultrasound-guided tru-cut biopsy as a complementary method for predicting pathological complete response in rectal cancer after neoadjuvant treatment: a phase II prospective and diagnostic trial
Authors: Yaoyi Huang, Yumo Xie, Puning Wang, Yao Chen, Si Qin, Fangqian Li, Yuanhui Wu, Mingzhe Huang, Zehui Hou, Yonghua Cai, Xiaosheng He, Hongcheng Lin, Bang Hu, Qiyuan Qin, Tenghui Ma, Shuyun Tan, Yi Liao, Jia Ke, Di Zhang, Sicong Lai, ZhiPeng Jiang, Huaiming Wang, Jun Xiang, Zerong Cai, Hui Wang, Xiaowen He, Zuli Yang, Donglin Ren, Xiaojian Wu, Yisong Hong, Meijin Huang, Yanxin Luo, Guangjian Liu, Jinxin Lin
Journal: International Journal of Surgery (2024)

Importance: Patients with pCR of rectal cancer following neoadjuvant treatment had better oncological outcomes. However, reliable methods for accurately predicting pCR remain limited. Objective: To evaluate whether transrectal ultrasound-guided tru-cut biopsy (TRUS-TCB) adds diagnostic value to conventional modalities for predicting pathological complete response (pCR) in patients with rectal cancer after neoadjuvant treatment. Design, Setting, and Participants: This study evaluated data of patients with rectal cancer who were treated with neoadjuvant treatment and reassessed using TRUS-TCB and conventional modalities before surgery. This study is registered with ClinicalTrials.gov. Main Outcomes and Measures: The primary outcome was accuracy, along with secondary outcomes including sensitivity, specificity, negative predictive value, and positive predictive value in predicting tumor residues. Final surgical pathology was used as reference standard. Results: Between June 2021 and June 2022, a total of 74 patients were enrolled, with 63 patients ultimately evaluated. Among them, 17 patients (28%) exhibited a complete pathological response. TRUS-TCB demonstrated an accuracy of 0.71 (95% CI, 0.58-0.82) in predicting tumor residues. The combined use of TRUS-TCB and conventional modalities significantly improved diagnostic accuracy compared to conventional modalities alone (0.75 vs. 0.59, P =0.02). Furthermore, TRUS-TCB correctly reclassified 52% of patients erroneously classified as having a complete clinical response by conventional methods. The occurrence of only one mild adverse event was observed. Conclusions and Relevance: Transrectal ultrasound-guided tru-cut biopsy (TRUS-TCB) proves to be a safe and accessible tool for reevaluation with minimal complications. The incorporation of TRUS-TCB alongside conventional methods leads to enhanced diagnostic performance.
A commentary on “In-hospital waiting time to surgery and functional outcomes in geriatric hip fractures: a directed acyclic graph-based preplanned analysis from a prospective multicenter cohort study
Authors: Lan Shen, Xueli He, Tianli Li, Yun Xiang, Mingbin Luo, Yan Zhang, Li Sun
Journal: International Journal of Surgery (2024)

Shen, Lan MM; He, Xueli MM; Li, Tianli MB; Xiang, Yun MM; Luo, Mingbin MM; Zhang, Yan MB; Sun, Li MM Author Information
A commentary on “early oral feeding versus nasojejunal early enteral nutrition in patients following pancreaticoduodenectomy: a propensity score-weighted analysis of 428 consecutive patients”
Authors: Meijing Li, Mengyi Yin, Xiaobei Jiang, Xiaotong Yang, Lu Liu
Journal: International Journal of Surgery (2024)

Hepatobiliary&Pancreatic&Spleen Surgery, Yantai Yuhuangding Hospital, Yantai, Shandong, China #Co-authors: Meijing Li and Mengyi Yin equally contributed to the article. Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article Published online ■ ■ *Corresponding author. Address: Hepatobiliary&Pancreatic&Spleen Surgery, Yantai Yuhuangding Hospital, Yantai, Shandong, China. E-mail address: [email protected] (L. Liu). This is an open access article distributed under the Creative Commons Attribution-ShareAlike License 4.0, which allows others to remix, tweak, and build upon the work, even for commercial purposes, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-sa/4.0/
Concomitant tricuspid valve surgery in patients undergoing left ventricular assist device: a systematic review and meta-analysis
Authors: Yuxiang Luo, Jiajie Leng, Rui Shi, Yingjiu Jiang, Dan Chen, Qingchen Wu, Hongtao Tie
Journal: International Journal of Surgery (2024)

Introduction: This study aims to investigate the effect of concomitant tricuspid valve surgery (TVS) during left ventricular assist device (LVAD) implantation due to the controversy over the clinical outcomes of concomitant TVS in patients undergoing LVAD. Methods: A systematic literature search was performed in PubMed and EMbase from the inception to Aug 1 st , 2023. Studies comparing outcomes in adult patients undergoing concomitant TVS during LVAD implantation (TVS group) and those who did not (no-TVS group) were included. The primary outcomes were right heart failure (RHF), right ventricular assist device (RVAD) implantation and early mortality. All meta-analyses were performed using random-effects models, and a two-tailed P &lt;0.05 was considered significant. Results: 21 studies were included, and 16 of them were involved in the meta-analysis, with 660 patients in the TVS group and 1291 in the no-TVS group. Patients in the TVS group suffered from increased risks of RHF (risk ratios [RR]=1.31, 95% confidence interval [CI]: 1.01-1.70, P =0.04; I 2 =38%, p H =0.13), RVAD implantation (RR=1.56, 95%CI: 1.16-2.11, P =0.003; I 2 =0%, p H =0.74), and early mortality (RR=1.61, 95%CI: 1.07-2.42, P =0.02; I 2 =0%, p H =0.75). Besides, the increased risk of RHF holds true in patients with moderate to severe tricuspid regurgitation (RR=1.36, 95%CI: 1.04-1.78, P =0.02). TVS was associated with a prolonged cardiopulmonary bypass time. No significant differences in acute kidney injury, re-operation requirement, hospital length of stay, or intensive care unit stay were observed. Conclusions: Concomitant TVS failed to show benefits in patients undergoing LVAD, and it was associated with increased risks of RHF, RVAD implantation, and early mortality.
A commentary on “The efficacy and safety of probiotics for prevention of chemoradiotherapy-induced diarrhea in people with abdominal and pelvic cancer: a systematic review and meta-analysis based on 23 randomized studies”
Authors: Qinjun Cai, Ying Shi
Journal: International Journal of Surgery (2024)

Department of Traditional Chinese Medicine, Beilun District People's Hospital, Beilun Branch of the First Affiliated Hospital of Zhejiang University, Ningbo, China, 315826 All data in this comment is available. Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: Department of Traditional Chinese Medicine, Beilun District People's Hospital, Beilun Branch of the First Affiliated Hospital of Zhejiang University, Ningbo, China, 315826. E-mail address:[email protected] (Y Shi). This is an open access article distributed under the Creative Commons Attribution-ShareAlike License 4.0, which allows others to remix, tweak, and build upon the work, even for commercial purposes, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-sa/4.0/
Bibliometric analysis of worldwide research trends on tumor burden and immunotherapy: A correspondence
Authors: Ji-Wei Geng, Qing Li, Wu-Xia Quan, Xin-Yu Lin, Yan-Dong Miao
Journal: International Journal of Surgery (2024)

aDepartment of Oncology, Baoshan People's Hospital, Baoshan 678000, China bCancer Center, Yantai Affiliated Hospital of Binzhou Medical University, The 2nd Medical College of Binzhou Medical University, Yantai 264100, China cSchool of Public Health, Shandong University, Jinan 250000, China Ji-Wei Geng and Qing Li: These authors contributed equally to this work. Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article *Corresponding author. Address: Cancer Center, Yantai Affiliated Hospital of Binzhou Medical University, The 2nd Medical College of Binzhou Medical University, Yantai 264100, China. E-mail address: [email protected] (Y-D. Miao). Supplemental Digital Content is available for this article. Direct URL citations are provided in the HTML and PDF versions of this article on the journal's website, www.lww.com/international-journal-of-surgery. Published online ■ ■ This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and non-commercial, as long as it is passed along unchanged and in whole, with credit to the author. http://creativecommons.org/licenses/by-nd/4.0/
A commentary on “Transversus thoracic muscle plane block for pain during cardiac surgery: a systematic review and meta-analysis”
Authors: Wei Zhong, Bo Zhao, Lei Liu, Gaoyuan Xi, Junhui Zhou
Journal: International Journal of Surgery (2024)

Department of Anesthesia,Henan Provincial Chest Hospital (Chest Hospital of Zhengzhou University),Zhengzhou,Henan 450000,China Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: Department of Anesthesia,Henan Provincial Chest Hospital (Chest Hospital of Zhengzhou University),Zhengzhou,Henan 450000,China. E-mail address: [email protected] (J Zhou). This is an open access article distributed under the Creative Commons Attribution-ShareAlike License 4.0, which allows others to remix, tweak, and build upon the work, even for commercial purposes, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-sa/4.0/
Nonsurgical salvage options for locally recurrent prostate cancer after primary definitive radiotherapy: A systematic review and meta-analysis
Authors: Jie Yang, Xingyu Xiong, Xinyang Liao, Weitao Zheng, Hang Xu, Lu Yang, Qiang Wei
Journal: International Journal of Surgery (2024)

Objective: To conduct a meta-analysis to provide the latest evidence of nonsurgical local salvage options in the first-line radiotherapy failure setting for localized prostate cancer patients. Background: Recurrence of localized prostate cancer after primary radiotherapy (RT) remains a clinical challenge. There is no consensus on optimal nonsurgical local salvage therapies, which mainly consist of cryotherapy (CRYO), high-intensity focused ultrasound (HIFU), high/low-dose-rate brachytherapy (HDR/LDR), and stereotactic body radiotherapy (SBRT). Methods: Our study was performed following the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. We systematically searched PubMed, Web of Science, Cochrane Library and ClinicalTrials.gov up to September 2023 to identify potentially relevant studies. The risk of bias was assessed using the European Association of Urology (EAU) items. Biochemical recurrence-free survival (bRFS) and genitourinary/gastrointestinal toxicities were the outcomes of interest. Pooled rates with 95% confidence intervals (CIs) were evaluated. Results: A total of 99 studies comprising 8440 patients were included. The pooled rate of 1-year biochemical control (BC) was highest for LDR (0.88, 95%CI 0.72-0.95) and lowest for SBRT (0.68, 95%CI 0.49-0.83). The pooled rate of 5-year BC was highest for CRYO (0.52, 95%CI 0.33-0.69) and lowest for HDR (0.23, 95%CI 0.08-0.51). HIFU presented the worst outcome of grade ≥3 genitourinary toxicities (GU3), with a rate of 0.22 (95%CI 0.12-0.3). Conversely, CRYO (0.09, 95%CI 0.04-0.14), HDR (0.05, 95%CI 0.02-0.07), LDR (0.10, 95%CI 0.06-0.14) and SBRT (0.06, 95%CI 0.03-0.09) presented low rates of GU3. All subgroups induced a quite low incidence of grade ≥3 gastrointestinal toxicities (GI3). Conclusions: Nonsurgical salvage therapies are promising modalities for prostate cancer in the local radiorecurrence setting. Based on the preliminary evidence from this study, CRYO and SBRT might present a relatively steady efficacy of BC with acceptable treatment-related toxicities.
Robotic-assisted retroperitoneal lymph node dissection for testicular cancer: benefit and limitation
Authors: Cheuk-Kwan Sun, I-Wen Chen, I-Ting Tsai, Kuo-Chuan Hung
Journal: International Journal of Surgery (2024)

aDepartment of Emergency Medicine, E-Da Dachang Hospital, I-Shou University, Kaohsiung City, Taiwan bSchool of Medicine, College of Medicine, I-Shou University, Kaohsiung city, Taiwan cDepartment of Anesthesiology, Chi Mei Medical Center, Liouying, Tainan city, Taiwan dDepartment of Emergency Medicine, E-Da Hospital, I-Shou University, Kaohsiung city, Taiwan eDepartment of Anesthesiology, Chi Mei Medical Center, Tainan city, Taiwan Shor title: Robotic-assisted RPLND for testicular cancer I-Wen Chen and Cheuk-Kwan Sun contributed equally as first authors to this work. Footnote: The affiliations for I-Wen Chen (affiliation 3) and Kuo-Chuan Hung (affiliation 5) represent different hospitals, despite both being under the Chi Mei Medical Center. These affiliations should not be combined or confused as they are distinct entities within different locations Published online ■ ■ *Corresponding Author. Address: Department of Anesthesiology, Chi Mei Medical Center, Tainan city, Taiwan, Chi Mei Medical Center, No.901, ChungHwa Road, YungKung Dist, Tainan 71004, Taiwan, Tel: +886-6-281-2811, Fax: +886-6-283-3806. E-mail address: [email protected] (K-C. Hung). This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0/
Ensuring ethical accountability in clinical surgery research: a call for review
Authors: Hinpetch Daungsupawong, Viroj Wiwanitkit
Journal: International Journal of Surgery (2024)

aPrivate Academic Consultant, Phonhong, Lao People's Democratic Republic bChandigarh University, Punjab, India Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: Private Academic Consultant, Phonhong, Lao People's Democratic Republic. E-mail address: [email protected] (H. Daungsupawong). This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/
Deep learning combining mammography and ultrasound images to predict the malignancy of BI-RADS US 4A lesions in women with dense breasts：a diagnostic study
Authors: Yaping Yang, Ying Zhong, Junwei Li, Jiahao Feng, Chang Gong, Yunfang Yu, Yue Hu, Ran Gu, Hongli Wang, Fengtao Liu, Jingsi Mei, Xiaofang Jiang, Jin Wang, Qinyue Yao, Wei Wu, Qiang Liu, Herui Yao
Journal: International Journal of Surgery (2024)

Objectives: We aimed to assess the performance of a deep learning (DL) model, based on a combination of ultrasound (US) and mammography (MG) images, for predicting malignancy in breast lesions categorized as Breast Imaging Reporting and Data System (BI-RADS) US 4A in diagnostic patients with dense breasts. Methods: A total of 992 patients were randomly allocated into the training cohort and the test cohort at a proportion of 4:1. Another, 218 patients were enrolled to form a prospective validation cohort. The DL model was developed by incorporating both US and MG images. The predictive performance of the combined DL model for malignancy was evaluated by sensitivity, specificity and area under the receiver operating characteristic curve (AUC). The combined DL model was then compared to a clinical nomogram model and to the DL model trained using US image only and to that trained MG image only. Results: The combined DL model showed satisfactory diagnostic performance for predicting malignancy in breast lesions, with an AUC of 0.940 (95% confidence interval [95%CI], 0.874~1.000) in the test cohort, and an AUC of 0.906 (95%CI, 0.817~0.995) in the validation cohort, which was significantly higher than the clinical nomogram model, and the DL model for US or MG alone ( P &lt;0.05). Conclusions: The study developed an objective DL model combining both US and MG imaging features, which was proven to be more accurate for predicting malignancy in the BI-RADS US 4A breast lesions of patients with dense breasts. This model may then be used to more accurately guide clinicians’ choices about whether performing biopsies in breast cancer diagnosis.
Development and validation of a nomogram for pneumonia risk in burn patients with inhalation injury: a multicenter retrospective cohort study
Authors: Shijie Li, Dawei Li, Yalong Li, Xizhu Liu, Yaoyao Song, Xiaoye Xie, Peng Luo, Huageng Yuan, Chuan’an Shen
Journal: International Journal of Surgery (2024)

Background: Burn patients with inhalation injury are at higher risk of developing pneumonia, and yet there is no reliable tool for the assessment of the risk for such patients at admission. This study aims to establish a predictive model for pneumonia risk for burn patients with inhalation injury based on clinical findings and laboratory tests. Method: This retrospective study enrolled 546 burn patients with inhalation injury. They were grouped into a training cohort and a validation cohort. The least absolute shrinkage and selection operator (LASSO) regression analysis and binary logistic regression analysis were utilized to identify risk factors for pneumonia. Based on the factors, a nomogram for predicting pneumonia in burn patients with inhalation injury was constructed. Areas under the receiver operating characteristic curves (AUC), calibration plots and decision curve analysis (DCA) were used to evaluate the efficiency of the nomogram in both the training and validation cohorts. Results: The training cohort included 432 patients, and the validation cohort included 114 patients, with a total of 225 (41.2%) patients experiencing pneumonia. Inhalation injury, tracheal intubation/tracheostomy, low serum albumin, and high blood glucose were independent risk factors for pneumonia in burn patients with inhalation injury and they were further used to build the nomogram. The AUC of the nomogram in the training and validation cohorts were 0.938 (95% CI, 0.917-0.960) and 0.966 (95% CI, 0.931-1), respectively. The calibration curve for probability of pneumonia showed optimal agreement between the prediction by nomogram and the actual observation, and the DCA indicated that the constructed nomogram conferred high clinical net benefit. Conclusion: This nomogram can accurately predict the risk of developing pneumonia for burn patients with inhalation injury, and help professionals to identify high-risk patients at an early stage as well as to make informed clinical decisions.
Colonic probiotic insufflation: clinical proposal for an economical game-changer for restoration of the gut microbiome in colorectal cancer and beyond
Authors: Ryan Varghese, Kavita Pal, Vikram Gota, Md. Fokhrul Islam
Journal: International Journal of Surgery (2024)

aPoona College of Pharmacy, Bharati Vidyapeeth (Deemed to be) University, Pune Maharashtra, 411038, India bDepartment of Clinical Pharmacology, Advanced Centre for Treatment, Research, and Education in Cancer, Tata Memorial Centre, Kharghar, Navi Mumbai, Maharashtra, 410210, India cHomi Bhabha National Institute, Anushakti Nagar, Mumbai, Maharashtra, 400094, India dDepartment of Pharmaceutical Sciences, Philadelphia College of Pharmacy, Saint Joseph's University, Philadelphia, Pennsylvania, 19104, USA eDepartment of Pharmacy, Jahangirnagar University, Dhaka, 1342, Bangladesh Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: Jahangirnagar University Dhaka, BANGLADESH. E-mail address: [email protected] (Md. F. Islam). This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0/
Age may be a moderator of operative time in patients undergoing transoral endoscopic thyroidectomy vestibular approach
Authors: Kuo-Chuan Hung, I-Ting Tsai, I-Wen Chen, Cheuk-Kwan Sun
Journal: International Journal of Surgery (2024)

aDepartment of Anesthesiology, Chi Mei Medical Center, Tainan city, Taiwan bDepartment of Emergency Medicine, E-Da Hospital, I-Shou University, Kaohsiung city, Taiwan cSchool of Medicine, College of Medicine, I-Shou University, Kaohsiung city, Taiwan dDepartment of Anesthesiology, Chi Mei Medical Center, Liouying, Tainan city, Taiwan eDepartment of Emergency Medicine, E-Da Dachang Hospital, I-Shou University, Kaohsiung City, Taiwan Short title: Age as a moderator of operative time Footnote: The affiliations for Kuo-Chuan Hung (affiliation 1) and I-Wen Chen (affiliation 4) represent different hospitals, despite both being under the Chi Mei Medical Center. These affiliations should not be combined or confused as they are distinct entities within different locations. I-Wen Chen and Cheuk-Kwan Sun: contributed equally as corresponding authors to this work. Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article Published online ■ ■ *Corresponding author. Address: Department of Emergency Medicine, E-Da Dachang Hospital, I-Shou University, No. 305, Dachang 1st Road, Sanmin District, Kaohsiung City, Taiwan. Tel: +886-7-6150011 ext 1007; Mobile: +886-975106203; fax: +886-7-6150915. E-mail address: [email protected], [email protected] (C-K. Sun). This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0/