tbuckley/cabot-search huggingface dataset:
Abstract 13168: Sustained Ventricular Tachycardia and Ventricular Fibrillation are Infrequent Events but are Associated with Increased Arrhythmic and All-cause Death Following Non-ST-Segment Elevation Acute Coronary Syndromes
Authors: Jonathan p Piccini, Jennifer A White, Rajendra H Mehta, Sana M Al-Khatib, Pierluigi Tricoci, Charles Pollack, Gilles Montalescot, Frans Van de Werf, C. M Gibson, Robert A Harrington, L. K Newby
Journal: Circulation (2010)

Background: Ventricular arrhythmias remain a lethal complication of acute coronary syndromes. However, the incidence and prognosis of sustained VT/VF in contemporary non-ST-segment elevation acute ...
Abstract P308: The Association of Vitamin K Intake and Status With the Metabolic Syndrome: A 10 Year Follow-Up Study
Authors: Veerle Dam, Geertje W Dalmeijer, Cees Vermeer, Yvonne T van der Schouw, Joline W Beulens
Journal: Circulation (2015)

Background: The Metabolic Syndrome (MetS) is a cluster of metabolic abnormalities and is associated with increased risk of type 2 diabetes, cardiovascular diseases and all-cause mortality. Vitamin K intake (phylloquinone/menaquinones) and vitamin K status are associated with several components of MetS, but the association with MetS has hardly been studied to date. Objective: To examine whether dietary intake and/or status of vitamin K are associated with occurrence of MetS and its components. Design: This study comprised of two cohorts, one of 402 women and one of 400 men (40-80 years). At follow-up 625 participants were still alive and willing to participate. Data were analyzed both cross-sectionally and longitudinally with Poisson and linear regression analyses adjusted for lifestyle and dietary factors. Baseline phylloquinone and menaquinone intake were measured with a validated food frequency questionnaire and dephospho-uncarborxylated matrix Gla protein was used as a marker for vitamin K status. Results: At baseline 285 (35.6%) participants had MetS and 172 (35.7%) at follow-up. Cross-sectionally, a high intake of menaquinones was associated (P trend =0.03) with a lower prevalence of MetS with a prevalence ratio (PR) of 0.70 (95%CI: 0.51-0.96) for the highest versus the lowest tertile. A high vitamin K status was also associated (P trend =0.02) with a reduced prevalence of MetS in cross-sectional analyses (PR T3 vs. T1 =0.73; 0.54-0.98) At follow-up, the highest tertiles of menaquinone intake (PR=0.62; 0.40-0.95) and vitamin K status (PR=0.61; 0.40-0.92) were associated (P trend &lt;0.02) with a lower occurrence of MetS. These associations were mainly driven by relations with lower triglyceride concentrations for menaquinones and lower waist circumference in women for vitamin K status. Phylloquinone intake was not associated with MetS prevalence. Conclusion: This study shows that a high intake of menaquinones and high vitamin K status are associated with a lower prevalence of MetS. This is mainly driven by the associations of high menaquinones intake with lower triglycerides concentrations and high vitamin K status with lower waist circumference in women.
Diagnostic Orthopaedic Pathology.
Authors: Colin Gerard Woods
Journal: Annals of Internal Medicine (1973)

Bcok reviews high incidence of transplacentally induced gliomas and nephroblastomas reported by the experimentalists has attracted much attention from the clinicians.Despite certain defects (notably the lack of an index), the present account provides a timely introduction to what is likely to be a rapidly expanding subject in clinical and experimental oncology.
Outcomes after Intermediate-Risk Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL) and the Role of Allogeneic Stem Cell Transplantation (SCT): A Report from Children's Oncology Group (COG) AALL0433
Authors: Glen Lew, Xiaomin Lu, Rochelle Yanofsky, Susan R. Rheingold, James Whitlock, Qi An, Meenakshi Devidas, Caroline A. Hastings, Naomi J. Winick, William L. Carroll, Michael J. Borowitz, Stephen Hunger, Michael A. Pulsipher
Journal: Blood (2014)
Anleitung zur Diathermiebehandlung.
Authors: Gustav Bucky
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Experts plan to recommend immediate antiretroviral therapy for people with HIV
Authors: A. O'Dowd
Journal: BMJ (2015)

The historiography of medicine has shifted from narratives of inevitable progress, authored mainly by the medical profession, to a more complex, analytical approach in which historians place medicine in its social context. However, the history of surgery has lagged behind somewhat; Christopher Lawrence suggests this is because the recent focus on the construction of medical knowledge does not incorporate the practical aspects of surgery, which are difficult to extract from their previous linear narrative. Thomas Schlich likewise recognises that surgery is both knowledge and skill—therefore more of a ‘craft’ than medicine. A possible solution is aligning the history of surgery with the history of technology: analysing the interplay of instruments and human activity. This case study uses the history of endoscopic endonasal pituitary surgery to explore the historiography of surgical innovation, in the context of its heavy reliance on both technology and interdisciplinary divisions of labour. Re-enactment, evolutionary frameworks and using Social Construction of Technology methods all require close collaboration between historian and surgeon to bridge the gap between scholarship and tacit knowledge.
Die innere Behandlung von Hautleiden.
Authors: S. Jessner
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A tumor-penetrating peptide enhances circulation-independent targeting of peritoneal carcinomatosis
Authors: Kazuki N. Sugahara, Pablo Scodeller, Gary B. Braun, Tatiana Hurtado de Mendoza, Chisato M. Yamazaki, Michael D. Kluger, Joji Kitayama, Edwin Alvarez, Stephen B. Howell, Tambet Teesalu, Erkki Ruoslahti, Andrew M. Lowy
Journal: Journal of Controlled Release (2015)
Pancreatic cystic lesions: the challenge of risk stratification for malignancy
Authors: Luca Barresi, Ilaria Tarantino, Dario Ligresti, Gabriele Curcio, Antonino Granata, Floriana Barbera, Loredana Bruno, Piergiulio Conaldi, Mario Traina
Journal: Endoscopy (2015)

We read with interest the study by Al-Haddad et al. [1] on the accuracy of integrated molecular pathology (IMP) testing in assessing the malignant potential of pancreatic cysts, and the comparison with the 2012 Sendai guideline management criteria model. The authors found that IMP testing can differentiate between the need for surveillance and the need for surgery more accurately than the Sendai criteria. We were surprised at the positive predictive value (PPV) calculated for the 2012 Sendai criteria for malignancy in this article. The authors found a PPV of 20.8 % for the Sendai criteria versus 57.9 % for IMP testing. This value is significantly lower than the PPV (88 %) for the 2012 Sendai criteria reported by Goh et al. [2].
Metastatic Malignant Fibrous Histiocytoma in the Stomach
Authors: Na Fang, Yan-Li Wang, Lei Zeng, Zeng-Jie Wu, Xin-Jian Cui
Journal: Clinical Nuclear Medicine (2015)

Metastatic malignant fibrous histiocytoma (MFH) in the stomach is extremely rare. We report a 73-year-old man with MFH in the left popliteal fossa that metastasized to the stomach. Whole-body 18F-FDG PET/CT showed abnormal tracer uptakes in the stomach, which was subsequently confirmed as metastatic MFH.
Abstract 3576: Mechanical Dyssynchrony and the Relationship between QRS Duration, Left Ventricular Systolic Function and Time to Peak Aortic Flow: the Strong Heart Study
Authors: Rakesh K Mishra, Suneet Mittal, Lyle G Best, Elisa T Lee, James M Galloway, Mary J Roman
Journal: Circulation (2006)

Background QRS duration on the surface electrocardiogram has been used to as a measure of ventricular mechanical dyssynchrony in the selection of heart failure patients for cardiac resynchronizatio...
Meeting Highlights of the 10th Annual Scientific Sessions of the Society for Cardiovascular Magnetic Resonance and 6th Annual Meeting of the Working Group for Cardiovascular Magnetic Resonance of the European Society of Cardiology
Authors: Matthias G. Friedrich, Christopher M. Kramer, Daniel K. Sodickson, Scott D. Flamm, Peter Buser, Stefan Neubauer
Journal: Journal of the American College of Cardiology (2007)
The rationing agenda in the NHS
Authors: B New
Journal: BMJ (1996)

<h3>Summary issues</h3> What is the range of services relevant to issues of health care rationing? What are the objectives of the NHS and what is the range of ethically defensible criteria for discriminating between competing claims for resources? Whose values should be taken into account? Who should undertake rationing? What accountability mechanisms are appropri- ate? How explicit should be the principles by which rationing is conducted? What additional information would be required to make rationing more explicit and those respon- sible more accountable? Is there enough knowledge to implement particular rationing strategies successfully?
REAR SEAT BELTS SHOULD BE ENCOURAGED BY A MIXTURE OF LEGISLATION AND INCENTIVES
Authors: D Yates
Journal: BMJ (1989)

This article reviews evidence which shows that the use of rear seat belts reduces severe injuries and fatalities in road accidents, and suggests ways of increasing their use by children. Evidence is taken from a variety of sources. Use of rear seat belts, especially by adults, is found to be infrequent, even though the pattern of injuries sustained in crashes is influenced more by the use of seat belts than by seating position. Most of the injuries caused to those in rear seats are due to changes in velocity rather than vehicle intrusion. Unbelted rear seat passengers have more numerous and more severe injuries than those who are restrained in the front seat and they are twice as likely to require hospitalization. Some two fifths of those who occupy rear seats are children, and surveys carried out in both the United Kingdom and New Zealand indicate that there is widespread public support for legislation which makes the use of rear seat belts by children compulsory. Such legislation should cater for the various requirements of each age of child, from babies to young teenagers. Car hire companies should also be required to provide a comprehensive range of restraint systems for all ages, and more child restraint leasing schemes should be established. (TRRL)
Investigation of HDAC inhibition targeting of BRCA1 expression as a mechanism to enhance platinum sensitivity in breast and ovarian cancer
Authors: J. I. Weberpals, A. O'Brien, K. Garbuio, K. Clark-Knowles, J. Dimitroulakos
Journal: Journal of Clinical Oncology (2009)

e22017 Background: The improved outcome of Breast-Cancer 1 (BRCA1)-deficient breast and ovarian cancer may be linked to the impaired ability to repair double strand breaks caused by DNA-damaging chemotherapy (CTX), such as platinum compounds. Therapeutically relevant agents that target BRCA1 expression to sensitize tumors to platinum have not been identified. In this study, we explore the effect of histone deacetylase inhibition (HDACi) on platinum sensitivity and BRCA1 expression in a breast and ovarian cancer cell line model. Methods: The efficacy of HDACi to potentiate the cytotoxicity of platinum-based chemotherapeutics was evaluated in a range of breast and ovarian tumor cell lines using the MTT cell viability assay and confirmed by flow cytometry. BRCA1 mRNA and protein expression was determined by Q-PCR and Western blot, respectively. The effect on DNA damage was measured by immunofluorescence staining and flow cytometry for γH2A.X foci, a hallmark for the presence of DNA double strand breaks. Results: Baseline BRCA1 expression was variable in two ovarian (A2780s, cisplatin-sensitive and A2780cp, cisplatin-resistant) and four breast cancer cell lines (MCF7, T47D, BT549 and HCC1937) with minimal and absent protein expression in BT549 and HCC1937, respectively. The addition of the HDACi, M344 increased the sensitivity of cells to cisplatin and carboplatin treatment in those cell lines with significant BRCA1 levels. Expression of BRCA1 protein decreased in response to the addition of HDACi to platinum in all cell lines. BRCA1 mRNA levels decreased with the addition of HDACi to platinum in all breast cancer lines and in A2780cp. A2780s and MCF7 cells subjected to combination platinum and HDACi treatment demonstrated increased levels of DNA damage, as assessed by the presence of phosphorylated γH2A.X foci. Conclusions: This study supports a novel mechanism of HDAC inhibition to sensitize breast and ovarian cancer cells to platinum via inhibition of the DNA repair protein BRCA1. BRCA1 expression changes may represent a novel biomarker to assess the activity of this combinational therapeutic approach in clinical evaluations of breast and ovarian cancer patients. No significant financial relationships to disclose.
Visual Outline of Psychiatry
Authors: Leland Earl Hinsie
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Consultant surgeons and vasectomy. (Letter to the editor)
Authors: Jackson Ln
Journal: BMJ (1973)

I was most interested to read Mrs. Marjorie Waites paper (June 16 p. 629) and I should like to comment on the section headed Inpatient or Outpatient?  In the 1000 cases followed up by the Simon Population Trust Vasectomy Project  published in 1969 no significant differences were reported in respect of minor postoperative complications (hematoma infection etc.) between men operated on under a local anesthetic and sent home the same day and those operated on under a  general anesthetic and retained overnight in hospital.  The work of the former Simon Population Trust Sterilization Project is now continuing with the same staff under the title the Crediton Project.  The vast majority of our applicants opt firmly for a local rather than a general anesthetic.(FULL TEXT)
Chemistry in Modern Life.
Authors: Svante Arrhenius, Clifford Shattuck Leonard
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 3682: Treatment of Patients with Severe Angina Pectoris Using Intracoronarily Injected Autologous Blood-Borne Angiogenic Cell Precursors
Authors: Damras Tresukosol, David Czeiger, Yael Porat, Danny Belkin, Adina Belleli, Michael Belkin, Valentin Fulga, Suphachai Chaithiraphan
Journal: Circulation (2006)

Background A pilot clinical trial was carried out to assess the safety and efficacy of intracoronary injection of VesCellTM, an autologous Angiogenic Cell Precursor (ACP)-based product for the trea...
Konstitutionstypen der Kinder.
Authors: W. S. Krasusky, Ernst Kretschmer
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Neurobiology of Cerebrospinal Fluid.
Authors: James H. Wood
Journal: Annals of Internal Medicine (1981)

This is the second in what will ultimately be a three volume treatise on applied aspects of the structure and function of blood vessels, and, as it appears from the present volume, lymphatic vessels.Although it suffers from some of the defects of the first volume, notably a somewhat haphazard placing of the different chapters, it is generally a much better piece of work.Following the pattern established in the first volume, the first chapter deals with historical aspects, in this instance, medieval and renaissance interpretations of the cardiovascular system.The rest of the first half of the book is taken up by chapters on the blood supply of the heart and lungs and of the brain.These are written to a much higher standard than many of the chapters on tissue and visceral blood supply in the preceding volume.The fact that they are followed by an authoritative account of lymphatics by F. C. Courtice, two short, but illuminating chapters on ageing and arterial structure and endothelial structure and ultrastructure by W. J. Cliff, and a reasoned and restrained discussion of the relationship between intimal cushions and atheroma by W. E. Stehbens also greatly enhances the value of the book.Indeed, if the standard set in this volume is maintained in the third, the series will go a long way towards achieving its aim of providing a comprehensive account of the structure and function of the circulation.A. D. HOYES
Medical Counseling before Pregnancy
Authors: Dorothy Reycroft Hollingsworth, Robert Resnik
Journal: Annals of Internal Medicine (1989)

This book is designed to help physicians and counsellors give the sound medical advice that will permit the best possible risk/benefit ratio for the foetus and new baby. It is divided into three practical sections: the broad factors influencing reproductive decisions and outcome of pregnancy, genetic counselling and preconception counselling for women with special medical problems. The editors bring together current advances in molecular biology, genetics, internal medicine, perinatology and neonatalology. They cover topics including infertility, repetitive spontaneous abortions and pregnancy after 35, the risks of drug exposure and possible workplace hazards and new methods for induction of ovulation, in vitro fertilization and other techniques for managing infertility. Counselling for genetic disorders, birth defects, metabolic diseases and diabetes are also covered.