tbuckley/cabot-search huggingface dataset:
Validating polyp and instrument segmentation methods in colonoscopy through Medico 2020 and MedAI 2021 Challenges
Authors: Debesh Jha, Vanshali Sharma, Debapriya Banik, Debayan Bhattacharya, Kaushiki Roy, Steven A Hicks, Nikhil Kumar Tomar, Vajira Thambawita, Adrian Krenzer, Ge-Peng Ji, Sahadev Poudel, George Batchkala, Saruar Alam, Awadelrahman M A Ahmed, Quoc-Huy Trinh, Zeshan Khan, Tien-Phat Nguyen, Shruti Shrestha, Sabari Nathan, Jeonghwan Gwak, Ritika K Jha, Zheyuan Zhang, Alexander Schlaefer, Debotosh Bhattacharjee, M K Bhuyan, Pradip K Das, Deng-Ping Fan, Sravanthi Parasa, Sharib Ali, Michael A Riegler, Pål Halvorsen, Thomas de Lange, Ulas Bagci
Journal: Medical Image Analysis (2024)
Erratum to “Treatment response biomarkers: working towards personalised radiotherapy for lung cancer. [Journal of Thoracic Oncology Vol. 19 No. 8: 1164–1185]”
Authors: Ashley Horne, Ken Harada, Katherine D Brown, Kevin Lee Min Chua, Fiona McDonald, Gareth Price, Paul Martin Putora, Dominic G Rothwell, Corinne Faivre-Finn
Journal: Journal of Thoracic Oncology (2024)
Gut-induced alpha-Synuclein and Tau propagation initiate Parkinson’s and Alzheimer’s disease co-pathology and behavior impairments
Authors: Jie Xiang, Jingrong Tang, Fei Kang, Jiajun Ye, Yueying Cui, Zhentao Zhang, Jing Wang, Shengxi Wu, Keqiang Ye
Journal: Neuron (2024)
Nanoneedle Array‐Electroporation Facilitates Intranuclear Ribonucleoprotein Delivery and High Throughput Gene Editing
Authors: Xinmin Liu, Juan Jiang, Jing Liu, Hao Yang, Zhangping Huang, Caiguanxi Deng, Yongyong Li, Liru Shang, Xiafeng Wang, Xi Xie, Ji Wang
Journal: Advanced Healthcare Materials (2024)

Abstract Dendritic cells (DCs) are critical regulators of T cell immunity, with immense therapeutic potential against tumors and autoimmune diseases. Efficient gene editing in DCs is crucial for understanding their regulatory mechanisms and maximizing their therapeutic efficacy. However, DCs are notoriously difficult to transfect, posing a major bottleneck for conventional DNA and RNA‐based editing approaches. Microneedle‐mediated injection of Cas9/sgRNA ribonucleoprotein (RNP) directly into the nucleus, akin to gene editing in reproductive cells, offers promise but suffers from limitations in scalability. Here, an intranuclear delivery system using a hollow nanoneedle array (HNA) combined with nano‐electroporation is developed. The 2 µm‐high HNA physically reaches the nucleus, positioning the nuclear envelope and plasma membrane in close proximity at the tip. Transient electronic pulses then induce simultaneous perforations across all 3 membranes, enabling direct RNP delivery into the nucleus. This HNA‐based system achieves efficient knockout of genes like PD‐L1 in primary DCs, demonstrating its potential as a powerful tool for gene editing in DCs and other hard‐to‐transfect cells.
Modeling memory B cell responses in a lymphoid organ-chip to evaluate mRNA vaccine boosting
Authors: Raphaël Jeger-Madiot, Delphine Planas, Isabelle Staropoli, Hippolyte Debarnot, Jérôme Kervevan, Héloïse Mary, Camilla Collina, Barbara F. Fonseca, Rémy Robinot, Stacy Gellenoncourt, Olivier Schwartz, Lorna Ewart, Michael Bscheider, Samy Gobaa, Lisa A. Chakrabarti
Journal: The Journal of Experimental Medicine (2024)

Predicting the immunogenicity of candidate vaccines in humans remains a challenge. To address this issue, we developed a lymphoid organ-chip (LO chip) model based on a microfluidic chip seeded with human PBMC at high density within a 3D collagen matrix. Perfusion of the SARS-CoV-2 spike protein mimicked a vaccine boost by inducing a massive amplification of spike-specific memory B cells, plasmablast differentiation, and spike-specific antibody secretion. Features of lymphoid tissue, including the formation of activated CD4+ T cell/B cell clusters and the emigration of matured plasmablasts, were recapitulated in the LO chip. Importantly, myeloid cells were competent at capturing and expressing mRNA vectored by lipid nanoparticles, enabling the assessment of responses to mRNA vaccines. Comparison of on-chip responses to Wuhan monovalent and Wuhan/Omicron bivalent mRNA vaccine boosts showed equivalent induction of Omicron neutralizing antibodies, pointing at immune imprinting as reported in vivo. The LO chip thus represents a versatile platform suited to the preclinical evaluation of vaccine-boosting strategies.
Impact of age on clinical outcomes and response to serelaxin in patients with acute heart failure: An analysis from the <scp>RELAX</scp>‐<scp>AHF</scp>‐2 trial
Authors: Riccardo M. Inciardi, Laura Staal, Beth Davison, Carlo M. Lombardi, Douwe Postmus, Michael G. Felker, Gerasimos Filippatos, Barry Greenberg, Peter S. Pang, Piotr Ponikowski, Thomas Severin, Claudio Gimpelewicz, John Teerlink, Gad Cotter, Adriaan A. Voors, Marco Metra
Journal: European Journal of Heart Failure (2024)
Organelle Specific Macrophage Engineered Vesicles Differentially Reprogram Macrophage Polarization
Authors: Khaga R. Neupane, Surya P. Aryal, Brock T. Harvey, Geraldine San Ramon, Byeong Chun, J. Robert McCorkle, Jill M. Kolesar, Peter M. Kekenes‐Huskey, Christopher I. Richards
Journal: Advanced Healthcare Materials (2024)

Abstract Tumor‐associated macrophages (TAMs) represent the majority of the immune cells present in the tumor microenvironment. These macrophages exhibit an anti‐inflammatory (M2)‐like physiological state and execute immune‐suppressive and tumor‐supporting properties. With TAMs being plastic, there is a growing interest in reprogramming them toward a pro‐inflammatory (M1)‐like phenotype that exhibits anti‐tumoral properties. Recent studies have demonstrated that both engineered vesicles derived from macrophages and endogenous extracellular vesicles produced by macrophages can be programmed to alter macrophage phenotype. Here it is demonstrated that pro‐inflammatory macrophage‐engineered subcellular vesicles (MEVs) have differential properties based on their organelle of origin. Endoplasmic reticulum specific MEVs (erMEVs) treated M2 macrophages exhibit enhanced pro‐inflammatory cytokine production compared to plasma membrane specific MEVs (pmMEVs) treated M2 macrophages. In addition, under in vitro co‐culture conditions, erMEVs elicit superior efficacy in suppressing the viability of cancer cells compared to the same concentration of pmMEVs. Furthermore, erMEVs and pmMEVs maintain differences in their membrane proteins, that regulate the repolarization efficacy of M2 macrophages toward an M1‐like phenotype. In addition, The M2 to M1 repolarizing efficacy of MEVs can be altered by changing the activity of the membrane proteins present on erMEVs or pmMEVs.
Extracellular Vesicles Delivered by a Nanofiber‐Hydrogel Composite Enhance Healing In Vivo in a Model of Crohn's Disease Perianal Fistula
Authors: Ling Li, Zhicheng Yao, Kevan J. Salimian, Jiayuan Kong, Atif Zaheer, Alyssa Parian, Susan L. Gearhart, Hai‐Quan Mao, Florin M. Selaru
Journal: Advanced Healthcare Materials (2024)

Abstract Perianal fistulas represent a common, aggressive, and disabling complication of Crohn's disease (CD). Despite recent drug developments, novel surgical interventions as well as multidisciplinary treatment approaches, the outcome is dismal, with &gt;50% therapy failure rates. Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSCs) offer potential therapeutic benefits for treating fistulizing CD, due to the pro‐regenerative paracrine signals. However, a significant obstacle to clinical translation of EV‐based therapy is the rapid clearance and short half‐life of EVs in vivo. Here, an injectable, biodegradable nanofiber‐hydrogel composite (NHC) microgel matrix that serves as a carrier to deliver MSC‐derived EVs to a rat model of CD perianal fistula (PAF) is reported. It is found that EV‐loaded NHC (EV‐NHC) yields the best fistula healing when compared to other treatment arms. The MRI assessment reveals that the EV‐NHC reduces inflammation at the fistula site and promotes tissue healing. The enhanced therapeutic outcomes are contributed by extended local retention and sustained release of EVs by NHC. In addition, the EV‐NHC effectively reduces inflammation at the fistula site and promotes tissue healing and regeneration via macrophage polarization and neo‐vascularization. This EV‐NHC platform provides an off‐the‐shelf solution that facilitates its clinical translation.
Association of Declining Prostate-specific Antigen Levels with Clinical Outcomes in Patients with Metastatic Castration-resistant Prostate Cancer Receiving [177Lu]Lu-PSMA-617 in the Phase 3 VISION Trial
Authors: Andrew J Armstrong, Oliver Sartor, Johann de Bono, Kim Chi, Karim Fizazi, Bernd J Krause, Ken Herrmann, Kambiz Rahbar, Scott T Tagawa, Fred Saad, Tomasz M Beer, Jiwen Wu, Osvaldo Mirante, Michael J Morris
Journal: European Urology (2024)
The sociality of sleep in animal groups
Authors: Pritish Chakravarty, Alison M Ashbury, Ariana Strandburg-Peshkin, Josefine Iffelsberger, Aya Goldshtein, Caroline Schuppli, Katherine R S Snell, Marie J E Charpentier, Chase L Núñez, Giulia Gaggioni, Nadja Geiger, Daniela C Rößler, Gabriella Gall, Pei-Pei Yang, Barbara Fruth, Roi Harel, Margaret C Crofoot
Journal: Trends in Ecology & Evolution (2024)
MnO2@CeOx-GAMP radiosensitizer with oxygen vacancies depended mimicking enzyme-like activities for radiosensitization-mediated STING pathway activation
Authors: Meiling Tan, Zhimin Gao, Xinyi Wang, Xiaozhao Wang, Chen Lin, Yongxin Huang, Wei Chen, Yaru Zhang, Zhiyao Hou
Journal: Biomaterials (2024)
Comparison of clinicopathological features and treatment outcomes for cutaneous melanomas of the head and neck and melanomas arising at other sites: implications for systemic therapy
Authors: Andrew T Li, Jessie X Xu, Tyler R Blah, Serigne N Lo, Robyn Pm Saw, Alexander Hr Varey, Alexander Van Akkooi, Matteo S Carlino, Ines Pires da Silva, Alexander M Menzies, Kerwin F Shannon, Georgina V Long, Richard A Scolyer, John F Thompson, Sydney Ch'ng
Journal: Journal of the American Academy of Dermatology (2024)
The global blood donation index: an imperfect measure of transfusion need
Authors: Jeremy W Jacobs, Imelda Bates, Claudia S Cohn, Nabajyoti Choudhury, Shirley Owusu-Ofori, Hans Vrielink, Eshan U Patel, Silvano Wendel, Aaron A R Tobian, Evan M Bloch
Journal: The Lancet (2024)
Safety and efficacy of ATSN-101 in patients with Leber congenital amaurosis caused by biallelic mutations in GUCY2D: a phase 1/2, multicentre, open-label, unilateral dose escalation study
Authors: Paul Yang, Laura P Pardon, Allen C Ho, Andreas K Lauer, Dan Yoon, Shannon E Boye, Sanford L Boye, Alejandro J Roman, Vivian Wu, Alexandra V Garafalo, Alexander Sumaroka, Malgorzata Swider, Iryna Viarbitskaya, Tomas S Aleman, Mark E Pennesi, Christine N Kay, Kenji P Fujita, Artur V Cideciyan
Journal: The Lancet (2024)
Gain-of-Function Variants in SMAD4 Compromise Respiratory Epithelial Function
Authors: Mark E Lindsay, Eleanor R Scimone, Joseph Lawton, Rashmi Richa, Lael M Yonker, Yuanpu P Di, Karen Buch, Wukun Ouyang, Xiulei Mo, Angela E Lin, Hongmei Mou
Journal: Journal of Allergy and Clinical Immunology (2024)
Modulating Pro-Fibrotic Macrophages Using Yeast Beta-Glucan Microparticles Prepared by Pressurized Gas eXpanded Liquid (PGX) Technology®
Authors: S Naiel, N Dowdall, Q Zhou, P Ali, A Hayat, M Vierhout, E Y Wong, R Couto, B Yépez, B Seifried, P Moquin, M R Kolb, K Ask, T Hoare
Journal: Biomaterials (2024)
Protection against fibrosis by a bacterial consortium in metabolic dysfunction-associated steatohepatitis and the role of amino acid metabolism
Authors: Suet-Ying Kwan, Kristyn A. Gonzales, Mohamed A. Jamal, Heather L. Stevenson, Lin Tan, Philip L. Lorenzi, P. Andrew Futreal, Ernest T. Hawk, Joseph B. McCormick, Susan P. Fisher-Hoch, Robert R. Jenq, Laura Beretta
Journal: Gut Microbes (2024)

The gut microbiota drives progression to liver fibrosis, the main determinant of mortality in metabolic dysfunction-associated steatohepatitis (MASH). In this study, we aimed to identify bacterial species associated with protection against liver fibrosis in a high-risk population, and test their potential to protect against liver fibrosis
Re: Johan Bjerner, Ola Bratt, Kirsti Aas, et al. Baseline Serum Prostate-specific Antigen Value Predicts the Risk of Subsequent Prostate Cancer Death—Results from the Norwegian Prostate Cancer Consortium. Eur Urol 2024;86:20–6
Authors: Rongkang Li, Lei Peng, Shaohua Zhang, Song Wu
Journal: European Urology (2024)
Hodgkin lymphoma: 2025 update on diagnosis, risk‐stratification, and management
Authors: Stephen M. Ansell
Journal: American Journal of Hematology (2024)

Abstract Disease Overview Hodgkin lymphoma (HL) is an uncommon B‐cell lymphoid malignancy affecting 8570 new patients annually and representing ~10% of all lymphomas in the United States. Diagnosis HL is composed of two distinct disease entities: classical HL and nodular lymphocyte predominant HL (also called nodular lymphocyte predominant B‐cell lymphoma). Nodular sclerosis, mixed cellularity, lymphocyte depletion, and lymphocyte‐rich HL are subgroups of classical HL. Risk Stratification An accurate assessment of the stage of disease in patients with HL is critical for the selection of the appropriate therapy. Prognostic models that identify patients at low or high risk for recurrence, as well as the response to therapy as determined by positron emission tomography (PET) scan, are used to optimize therapy. Risk‐Adapted Therapy Initial therapy for HL patients is based on the histology of the disease, the anatomical stage and the presence of poor prognostic features. Patients with early‐stage disease are typically treated with combined modality strategies utilizing abbreviated courses of combination chemotherapy followed by involved‐field radiation therapy, whereas those with advanced stage disease receive a longer course of chemotherapy often without radiation therapy. However, newer agents including brentuximab vedotin and anti‐PD‐1 antibodies are now standardly incorporated into frontline therapy. Management of Relapsed/Refractory Disease High‐dose chemotherapy (HDCT) followed by an autologous stem cell transplant (ASCT) is the standard of care for most patients who relapse following initial therapy. For patients who fail HDCT with ASCT, brentuximab vedotin, PD‐1 blockade, non‐myeloablative allogeneic transplant or participation in a clinical trial should be considered.
Peri-domestic entomological surveillance using private traps allows detection of dengue virus in Aedes albopictus during an autochthonous transmission event in mainland France, late summer 2023
Authors: Barbara Viginier, Raphaëlle Klitting, Clémence Galon, Violaine Bonnefoux, Christophe Bellet, Albin Fontaine, Élise Brottet, Marie-Claire Paty, Armelle Mercurol, Nathalie Ragozin, Sara Moutailler, Gilda Grard, Xavier de Lamballerie, Frédérick Arnaud, Maxime Ratinier, Vincent Raquin
Journal: Eurosurveillance (2024)

While locally-acquired dengue virus (DENV) human infections occur in mainland France since 2010, data to identify the mosquito species involved and to trace the virus are frequently lacking. Supported by a local network gathering public health agencies and research laboratories, we analysed, in late summer 2023, mosquitoes from privately-owned traps within a French urban neighbourhood affected by a dengue cluster. The cluster, in Auvergne-Rhône-Alpes, comprised three cases, including two autochthonous ones. Upon return from a recent visit to the French Caribbean Islands, the third case had consulted healthcare because of dengue-compatible symptoms, but dengue had not been recognised. For the two autochthonous cases, DENV-specific antibodies in serum or a positive quantitative PCR for DENV confirmed DENV infection. The third case had anti-flavivirus IgMs. No DENV genetic sequences were obtained from affected individuals but
An outbreak of Shiga toxin-producing Escherichia coli (STEC) O157:H7 associated with contaminated lettuce and the cascading risks from climate change, the United Kingdom, August to September 2022
Authors: Neil Cunningham, Claire Jenkins, Sarah Williams, Joanna Garner, Bernd Eggen, Amy Douglas, Tina Potter, Anthony Wilson, Giovanni Leonardi, Lesley Larkin, Susan Hopkins
Journal: Eurosurveillance (2024)

Shiga-toxin producing Escherichia coli (STEC) O157 is a food-borne pathogen which causes gastrointestinal illness in humans. Ruminants are considered the main reservoir of infection, and STEC exceedance has been associated with heavy rainfall. In September 2022, a large outbreak of STEC O157:H7 was identified in the United Kingdom (UK). A national-level investigation was undertaken to identify the source of the outbreak and inform risk mitigation strategies. Whole genome sequencing (WGS) was used to identify outbreak cases. Overall, 259 cases with illness onset dates between 5 August and 12 October 2022, were confirmed across the UK. Epidemiological investigations supported a UK grown, nationally distributed, short shelf-life food item as the source of the outbreak. Analytical epidemiology and food chain analysis suggested lettuce as the likely vehicle of infection. Food supply chain tracing identified Grower X as the likely implicated producer. Independent of the food chain investigations, a novel geospatial analysis triangulating meteorological, flood risk, animal density and land use data was developed, also identifying Grower X as the likely source. Novel geospatial analysis and One Health approaches are potential tools for upstream data analysis to predict and prevent contamination events before they occur and to support evidence generation in outbreak investigations.
The hidden base of the iceberg: gut peptidoglycome dynamics is foundational to its influence on the host
Authors: Richard Wheeler, Ivo Gomperts Boneca
Journal: Gut Microbes (2024)

The intestinal microbiota of humans includes a highly diverse range of bacterial species. All these bacteria possess a cell wall, composed primarily of the macromolecule peptidoglycan. As such, the gut also harbors an abundant and varied peptidoglycome. A remarkable range of host physiological pathways are regulated by peptidoglycan fragments that originate from the gut microbiota and enter the host system. Interactions between the host system and peptidoglycan can influence physiological development and homeostasis, promote health, or contribute to inflammatory disease. Underlying these effects is the interplay between microbiota composition and enzymatic processes that shape the intestinal peptidoglycome, dictating the types of peptidoglycan generated, that subsequently cross the gut barrier. In this review, we highlight and discuss the hidden and emerging functional aspects of the microbiome, i.e. the hidden base of the iceberg, that modulate the composition of gut peptidoglycan, and how these fundamental processes are drivers of physiological outcomes for the host.
Integrative proteogenomic profiling of high-risk prostate cancer samples from Chinese patients indicates metabolic vulnerabilities and diagnostic biomarkers
Authors: Baijun Dong, Jun-Yu Xu, Yuqi Huang, Jiacheng Guo, Qun Dong, Yanqing Wang, Ni Li, Qiuli Liu, Mingya Zhang, Qiang Pan, Hanling Wang, Jun Jiang, Bairun Chen, Danqing Shen, Yiming Ma, Linhui Zhai, Jian Zhang, Jing Li, Wei Xue, Minjia Tan, Jun Qin
Journal: Nature Cancer (2024)
Efferocytosis drives a tryptophan metabolism pathway in macrophages to promote tissue resolution
Authors: Santosh R Sukka, Patrick B Ampomah, Lancia N F Darville, David Ngai, Xiaobo Wang, George Kuriakose, Yuling Xiao, Jinjun Shi, John M Koomen, Robert H McCusker, Ira Tabas
Journal: Nature Metabolism (2024)
Genomic analysis of Vibrio cholerae O1 isolates from cholera cases, Europe, 2022
Authors: Caroline Rouard, David R Greig, Thamida Tauhid, Susann Dupke, Elisabeth Njamkepo, Ettore Amato, Boas van der Putten, Umaer Naseer, Marion Blaschitz, Georgia D Mandilara, James Cohen Stuart, Alexander Indra, Harold Noël, Theologia Sideroglou, Florian Heger, Maaike van den Beld, Astrid Louise Wester, Marie-Laure Quilici, Holger C Scholz, Inga Fröding, Claire Jenkins, François-Xavier Weill
Journal: Eurosurveillance (2024)

BackgroundThe number of cholera cases reported to the World Health Organization (WHO) in 2022 was more than double that of 2021. Nine countries of the WHO European Region reported 51 cases of cholera in 2022 vs five reported cases in 2021.AimWe aimed to confirm that the
Worrying increase in the risk of vertical transmission of syphilis in Croatia, 2020 to 2024
Authors: Tatjana Nemeth Blažić, Nina Krajcar, Mirjana Lana Kosanović Ličina, Dominik Ljubas, Otilia Mardh, Ivana Božičević
Journal: Eurosurveillance (2024)

Four infants potentially exposed to syphilis infection in utero, meeting World Health Organization surveillance criteria of congenital syphilis (CS), were diagnosed in Croatia between September 2020 and January 2024. We conducted a retrospective analysis of epidemiological, clinical and laboratory data of these cases to assess compliance with surveillance case definitions. As only one confirmed CS case has been reported in Croatia in over 2 decades, these reports signal an increased risk of syphilis vertical transmission and warrant strengthening antenatal screening.
NAC1 promotes stemness and regulates myeloid-derived cell status in triple-negative breast cancer
Authors: Chrispus Ngule, Ruyi Shi, Xingcong Ren, Hongyan Jia, Felix Oyelami, Dong Li, Younhee Park, Jinhwan Kim, Hami Hemati, Yi Zhang, Xiaofang Xiong, Andrew Shinkle, Nathan L Vanderford, Sara Bachert, Binhua P Zhou, Jianlong Wang, Jianxun Song, Xia Liu, Jin-Ming Yang
Journal: Molecular Cancer (2024)
Most pleiotropic effects of gene knockouts are evolutionarily transient in yeasts
Authors: Li Liu, Yao Liu, Lulu Min, Zhenzhen Zhou, Xingxing He, YunHan Xie, Waifang Cao, Shuyun Deng, Xiaoju Lin, Xionglei He, Xiaoshu Chen
Journal: Molecular Biology and Evolution (2024)

Pleiotropy, the phenomenon in which a single gene influences multiple traits, is a fundamental concept in genetics. However, the evolutionary mechanisms underlying pleiotropy require further investigation. In this study, we conducted parallel gene knockouts targeting 100 transcription factors in 2 strains of Saccharomyces cerevisiae. We systematically examined and quantified the pleiotropic effects of these knockouts on gene expression levels for each transcription factor. Our results showed that the knockout of a single gene generally affected the expression levels of multiple genes in both strains, indicating various degrees of pleiotropic effects. Strikingly, the pleiotropic effects of the knockouts change rapidly between strains in different genetic backgrounds, and ∼85% of them were nonconserved. Further analysis revealed that the conserved effects tended to be functionally associated with the deleted transcription factors, while the nonconserved effects appeared to be more ad hoc responses. In addition, we measured 184 yeast cell morphological traits in these knockouts and found consistent patterns. In order to investigate the evolutionary processes underlying pleiotropy, we examined the pleiotropic effects of standing genetic variations in a population consisting of ∼1,000 hybrid progenies of the 2 strains. We observed that newly evolved expression quantitative trait loci impacted the expression of a greater number of genes than did old expression quantitative trait loci, suggesting that natural selection is gradually eliminating maladaptive or slightly deleterious pleiotropic responses. Overall, our results show that, although being prevalent for new mutations, the majority of pleiotropic effects observed are evolutionarily transient, which explains how evolution proceeds despite complicated pleiotropic effects.
Identifying optimal reference genes for qRT-PCR in human myocardial tissues
Authors: Maria Camacho-Encina, Laura K Booth, Rachael Redgrave, Minna Honkanen-Scott, William E Scott, Carmen Martin-Ruiz, Guy MacGowan, Sarah Richardson, John Dark, Simon Tual-Chalot, Gavin D Richardson
Journal: Cardiovascular Research (2024)