tbuckley/cabot-search huggingface dataset:
SAT-269 Molecular epidemiology of hepatitis delta virus in Spain using whole-genome sequencing
Authors: Ana Alberola Romano, Adolfo de Salazar, Lucía Chaves-Blanco, Marta Illescas-López, Ana Fuentes, Alberto Vázquez Blanquiño, Carolina Freyre, Valle Odero, Teresa Cabezas Fernandez, Carmen Liébana, Alejandro González Praetorius, Raquel Carracedo, Ricardo Arcay, Maitane Aranzamendi Zaldumbide, Roberto Alonso Fernández, Eva Cascales, Luz Moldes, Matilde Trigo, María José Gude, Iker Falces, Patricia Ordóñez, Sandra Cortizo, María Reyes Vidal-Acuña, Maria del Rosario Sanchez Benito, Encarnación Ramirez Arellano, M. Pilar Luzón-García, Ana Maria Domínguez Castaño, Natalia Montiel, Antonio Sampedro, Francisco Franco Álvarez De La Luna, Ana Belen Perez Jimenez, Alberto De La Iglesia Salgado, Ana Miqueleiz Zapatero, Belen Lorenzo, Carmen Gómez, Gabriel Reina, Fernando Fernández Sánchez, Juan Carlos Galán, Isabel Viciana, José Joaquín Blas Señalada, Magdalena Lara, Luis Elorduy Otazua, Ana Rodríguez-Fernández, Dolores Ocete, María Asunción Iborra, Beatriz Castro Hernández, Susana Rojo Alba, Berta Becerril Carral, Marta Lerate Alba, Gonzalo Rivas Hernández, Sonia Algarate Cajo, Pablo Fraile Ribot, Miriam Blasco, María Carmen Lozano Domínguez, Paloma Liendo, Maria Jesus Del Amor Espin, Sonsoles Garcinuño Pérez, Yasmina Martin, Maria Aroca, Maria Lourdes Molina, Pablo Fernández, Margarita Cámara, María José López de Goikoetxea, María Luz Núñez, María García Valero, Esther Manrique González, Antonio Puerta, César Gómez, Inocencio Beltrán Cifuentes, Pilar Álvarez Sastre, Marta Sandoval Torrientes, Alicia Beteta López, Susana García-De Cruz, Ruth Saez, María José Pena, A. Aguilera, Federico García
Journal: Journal of Hepatology (2025)
SAT-285-YI Performance of the PAGE-B score for the prediction of hepatocellular carcinoma in chronic hepatitis B patients with metabolic dysfunction
Authors: Lesley Patmore, Ivana Carey, Jordan J. Feld, Willem Pieter Brouwer, Keyur Patel, Maria Buti, Pieter Honkoop, Douwe Postma, Hans Blokzijl, Ozgur Koc, Kosh Agarwal, Marc van der Valk, Faydra Lieveld, Mai Kilany, Matthijs Kramer, Joep de Bruijne, Mark Claassen, Bettina E. Hansen, Robert A. de Man, Harry L.A. Janssen, R. Bart Takkenberg, Milan J. Sonneveld
Journal: Journal of Hepatology (2025)
THU-495-YI The role of aryl hydrocarbon receptor across different cellular targets in pectin’s improvement of alcohol-associated liver disease
Authors: Wanchao Hu, Geraldine Schlecht-Louf, Nicolas Trainel, Aurore Desmons, Gerard Eberl, Francoise Mercier-Nome, Sophie Viel, Gabriel Perlemuter, Dragos Ciocan, Anne-Marie Cassard
Journal: Journal of Hepatology (2025)
SAT-453 MASH resolution index, a novel, highly sensitive non-invasive measure of histologic improvement, predicts high rates of MASH resolution with pemvidutide treatment of metabolic dysfunction-associated steatohepatitis (MASH)
Authors: Rohit Loomba, John Suschak, Julio Gutierrez, Jay Yang, M. Scot Roberts, M. Scott Harris, Sarah Browne, Daniel Huang, Shaheen Tomah
Journal: Journal of Hepatology (2025)
OS-098 Direct effects of survodutide on liver endpoints beyond weight loss: insights from a phase 2 trial of the glucagon receptor/glucagon-like peptide-1 receptor dual agonist survodutide in people with metabolic dysfunction-associated steatohepatitis and fibrosis
Authors: Mazen Noureddin, Arun J. Sanyal, Pierre Bedossa, Mandy Fraessdorf, Corinna Schoelch, Elena Startseva, GuyW. Neff, Eric J. Lawitz, Elisabetta Bugianesi, Quentin M. Anstee, Philip N. Newsome, Vlad Ratziu, Azadeh Hosseini-Tabatabaei, Jörn M. Schattenberg, Naim Alkhouri, Ramy Younes
Journal: Journal of Hepatology (2025)
WED-312 Pharmacokinetics, pharmacodynamics, and safety of bulevirtide 10 mg once daily for 6 days in participants with moderate hepatic impairment and in matched control participants with normal hepatic function
Authors: Parag Kumar, Wildaliz Nieves, Carolina Machado, Steve Tseng, Yuejiao Jiang, YeHong Wang, Ann Qin, Teckla Akinyi, Renee-Claude Mercier
Journal: Journal of Hepatology (2025)
THU-261 Monotherapy with the novel capsid assembly modulator ALG- 000184 for up to 96 weeks results in profound and sustained HBV DNA suppression in untreated subjects with chronic HBV infection
Authors: Man-Fung Yuen, Kosh Agarwal, Alina Jucov, Alexei Haceatrean, Min Wu, Kha Le, Thanh Van, Jen Rito, Lawrence Blatt, Sushmita Chanda, Tse-I Lin, Hardean Achneck, Edward J. Gane
Journal: Journal of Hepatology (2025)
WED-294 Virological response and safety of combination treatment with bulevirtide and pegylated interferon in chronic hepatitis D patients with advanced fibrosis/cirrhosis: 48 weeks interim results from SEE-D trial
Authors: Karin Lindahl, Habiba Kamal, Katarina Århem, Susanne Cederberg, Annika Olsson, Niklas Björkström, Soo Aleman
Journal: Journal of Hepatology (2025)
TOP-001-YI Community-based screening of viral hepatitis infections among high risk migrant and refugee populations in Greece, Italy and Spain: 2-year results of the VH-COMSAVAC project
Authors: Camila Picchio, Aina Nicolàs Olivé, George Kalamitsis, Ioanna Liatsou, Guiseppe Colucci, Enrico Sguazzini, Cristina Arcas, José A. Pérez Molina, Sandra Chamorro -Tojeiro, Ignacio Peña Ruiz, Angelo Pezzullo, Domenico Pascucci, Jeffrey Lazarus
Journal: Journal of Hepatology (2025)
THU-027 Vibration-controlled transient elastography dynamics in the general population: longitudinal results from the LiverScreen consortium
Authors: Jesse Pustjens, Katrine Bech, Guillem Pera, Helle Schnefeld, Laurens A. van Kleef, Robert J. de Knegt, Peter Andersen, Johanne Kragh Hansen, Llorenç Caballeria, Carla Chacon, Pere Torán, Sarwa Darwish Murad, Anita Arslanow, Harry L.A. Janssen, Aleksander Krag, Isabel Graupera, Maja Thiele, Willem Pieter Brouwer
Journal: Journal of Hepatology (2025)
WED-309-YI Response-guided interferon add-on to bulevirtide treatment: updated real-world insights from the austrian hepatitis D cohort study
Authors: Michael Schwarz, Caroline Schwarz, Marlene Panzer, Nikolaus Pfisterer, Nina Loschko, Lukas Hartl, Livia Dorn, Hermann Laferl, Michael Trauner, Albert Friedrich Stättermayer, Mattias Mandorfer, Ivo Graziadei, Andreas Maieron, Alexander Moschen, Elmar Aigner, Christian Madl, Stephan Aberle, Heinz Zoller, Michael Gschwantler, Thomas Reiberger, Mathias Jachs
Journal: Journal of Hepatology (2025)
SAT-336 Prevalence and characterization of hepatobiliary involvement in cystic fibrosis patients at a referral hospital
Authors: Carla de Sárraga, Andrea Peña, Mercedes Vergara, Mireia Miquel, Meritxell Casas, Cristina Solé, José Ferrusquía-Acosta, Valentí Puig-Diví, Alba Lira, Javier Pomares, Concepción Montón, Claudia Torras, Isabel Laucirica, Judith Cortada, Mar Salas, Laura Llovet, Jordi Sánchez
Journal: Journal of Hepatology (2025)
OS-028-YI In vivo stimulation of 4-1BB signaling enhances the efficacy of therapeutic vaccination in high-titer hepatitis B virus carrier mice
Authors: Edanur Ates-Öz, Osman Merdan, Emilio Dorigatti, Merve Gültan, Ioanna Gemünd, Benjamin Schubert, Ulrike Protzer, Anna D. Kosinska
Journal: Journal of Hepatology (2025)
WED-512-YI Validation of Baveno VII criteria for non-invasive diagnosis of clinically significant portal hypertension: systematic review and individual patient data meta-analysis
Authors: Juan Bañares, Monica Pons, Thomas Reiberger, Mattias Mandorfer, Mathias Jachs, Georg Semmler, Antonio Colecchia, Luigi Colecchia, Elton Dajti, Christophe Bureau, Héleène Larrue, Ivica Grgurevic, Petra Dinjar Kujundžic, Jose Ignacio Fortea, Angela Puente, Annalisa Berzigotti, Emmanuel Tsochatzis, Jaime Bosch, Juan G. Abraldes, Joan Genesca
Journal: Journal of Hepatology (2025)
GS-003 Circulating CD8 T cells are sentinels for intrahepatic T cell responses during HBV infection
Authors: Hannah Wintersteller, Sainitin Donakonda, Ioanna Gemünd, Miriam Bosch, Gustavo Almeida, Christine Wurmser, Roni Souleiman, Edanur Ates-Öz, Anna D. Kosinska, Anna Fürst, Sofía Pérez-del-Pulgar, Sabela Lens, Markus Cornberg, Maike Hofmann, Robert Thimme, Dietmar Zehn, Ulrike Protzer, Dirk Wohlleber, Percy A. Knolle
Journal: Journal of Hepatology (2025)
WED-019 Direct measurement of incidence and prevalence of Hepatitis C infection using the gold-standard of prospective HCV re-testing of people at risk. A national needs assessment of people who inject drugs and of all people who use addiction services in England
Authors: Beatrice Emmanouil, Mark Gillyon-Powell, Specioza Nabiteeko, Peter Sandwith, Stuart Smith, Georgia Threadgold, Graham R Foster
Journal: Journal of Hepatology (2025)
THU-211 PRO-Link HCV: automated detection and Re-engagement of hepatitis C patients lost to follow-up. A pilot study in southern Spain
Authors: Alberto Vázquez Blanquiño, Ana Fuentes, Francisco Franco Álvarez De La Luna, Lucía Pérez-Rodríguez, Marta Illescas-López, Lucía Chaves-Blanco, Ana Belén Pérez, Federico García
Journal: Journal of Hepatology (2025)
WED-274 Real-world outcomes in patients with Voxilaprevir (VOX)/ Velpatasvir (VEL)/Sofosbuvir (SOF) treatment failure: a follow-up study
Authors: Julia Dietz, Christiana Graf, Tobias Böttler, Kerstin Port, Christoph P. Berg, Katja Deterding, Kai-Henrik Peiffer, Georg Dultz, Miriam M. Düll, Christian Labenz, Julian Schulze zur Wiesch, Beat Müllhaupt, Andreas E. Kremer, Heinz Zoller, Stefan Zeuzem, Christoph Sarrazin
Journal: Journal of Hepatology (2025)
WED-469 Novel point-of-care, rapid breath test to identify subjects with metabolic-dysfunction associated steatotic liver disease with advanced fibrosis - a pilot study
Authors: Osnat Sella Tavor, Orit Marom Albeck, Ilay Marom, Omer Meroz, Gilad Feinberg, Rifaat Safadi
Journal: Journal of Hepatology (2025)
THU-231 Microelimination project for HCV in patients with elevated ALT using pooling PCR technique in a health area. Preliminary results
Authors: Natalia Marcos Carrasco, Elena Velasco Martinez, Belen Lorenzo, Carolina Almohalla, Irene Peñas Herrero, Félix García Pajares, Pedro Enrile Sanchez, Jorge Lillo Diez, Isabel Ruiz Nunez, Jorge Ruiz Rodríguez, Jose Maria Eiros Bouza, Gloria Sánchez Antolín
Journal: Journal of Hepatology (2025)
Age‐stratified machine learning identifies divergent prognostic significance of molecular alterations in AML
Authors: Jan‐Niklas Eckardt, Waldemar Hahn, Rhonda E. Ries, Szymon D. Chrost, Susann Winter, Sebastian Stasik, Christoph Röllig, Uwe Platzbecker, Carsten Müller‐Tidow, Hubert Serve, Claudia D. Baldus, Christoph Schliemann, Kerstin Schäfer‐Eckart, Maher Hanoun, Martin Kaufmann, Andreas Burchert, Johannes Schetelig, Martin Bornhäuser, Markus Wolfien, Soheil Meshinchi, Christian Thiede, Jan Moritz Middeke
Journal: HemaSphere (2025)

Abstract Risk stratification in acute myeloid leukemia (AML) is driven by genetics, yet patient age substantially influences therapeutic decisions. To evaluate how age alters the prognostic impact of genetic mutations, we pooled data from 3062 pediatric and adult AML patients from multiple cohorts. Signaling pathway mutations dominated in younger patients, while mutations in epigenetic regulators, spliceosome genes, and TP53 alterations became more frequent with increasing age. Machine learning models were trained to identify prognostic variables and predict complete remission and 2‐year overall survival, achieving area‐under‐the‐curve scores of 0.801 and 0.791, respectively. Using Shapley (SHAP) values, we quantified the contribution of each variable to model decisions and traced their impact across six age groups: infants, children, adolescents/young adults, adults, seniors, and elderly. The highest contributions to model decisions among genetic variables were found for alterations of NPM1 , CEBPA , inv(16), and t(8;21) conferring favorable risk and alterations of TP53, RUNX1, ASXL1 , del(5q), ‐7, and ‐17 conferring adverse risk, while FLT3 ‐ITD had an ambiguous role conferring favorable treatment responses yet poor overall survival. Age significantly modified the prognostic value of genetic alterations, with no single alteration consistently predicting outcomes across all age groups. Specific alterations associated with aging such as TP53 , ASXL1 , or del(5q) posed a disproportionately higher risk in younger patients. These results challenge uniform risk stratification models and highlight the need for context‐sensitive AML treatment strategies.
SAT-352 Genetic and epidemiological profile of a large brazilian cohort of acute hepatic porphyria
Authors: Cibele Franz, Barbara Cristina Vieira de Aquino, Liliana Sampaio Costa Mendes, Karina Lebeis Pires, Francismar Prestes Leal, Maria Chiara Chindamo, Wladimir Bocca Vieira de Rezende Pinto, Paulo Lima Serrano, Paulo Sgobbi
Journal: Journal of Hepatology (2025)
WED-476-YI Misclassification in non-invasive tests for liver fibrosis is expected: an example predicting liver stiffness in an international cohort
Authors: Rickard Strandberg, Jerome Boursier, Elisabetta Bugianesi, Chan Wah Kheong, Jiangao Fan, George Boon Bee Goh, Victor de Ledinghen, Atsushi Nakajima, Philip N. Newsome, Salvatore Petta, Manuel Romero-Gómez, Arun J. Sanyal, Ming-Hua Zheng, José Luis Calleja Panero, Emmanuel Tsochatzis, Céline Fournier-Poizat, Sau-Wai Mandy Chan, Grace Fong, Laurent Castera, Michelle Lai, Hannes Hagström
Journal: Journal of Hepatology (2025)
FRI-285 A novel quintuplex long-amplicon droplet digital PCR assay reveals greater quantities of hepatitis B virus splice variants in people with HBV/HIV co-infection compared to HBV mono- infection
Authors: Tanner Grudda, Chenkai Jiang, Nel Jason Haw, Steven Wolinsky, Kara Chew, Yue Chen, Jodie Dionne, Margaret Fischl, Igho Ofotokun, Nancie Archin, Eric Seaberg, Audrey French, Jennifer Price, Amanda Spence, Mark Kuniholm, Matthew Akiyama, Ashwin Balagopal, Chloe Thio
Journal: Journal of Hepatology (2025)
WED-324 Single-cell sequencing reveals heterogeneity differences in cholangiocyte organoids derived from biliary atresia patients compared to non-biliary atresia controls
Authors: Adi Har-Zahav, Yara Hamody, Keren Danan, Keren Rozen, Michael Gurevich, Raanan Shamir, Irit Gat-Viks, Orith Waisbourd-Zinman
Journal: Journal of Hepatology (2025)
FRI-262-YI Isogenic studies of basal-core promoter and precore mutations in hepatitis B genotype c
Authors: Leon Louis Seifert, Georgios Dangas, Yingpu Yu, Chenhui Zou, Catherine Freije, Xupeng Hong, Mengyin Zhang, Corrine Quirk, Yichen Zhou, Kosuke Ogata, Charles Rice, William Schneider, Eleftherios Michailidis, Ype de Jong
Journal: Journal of Hepatology (2025)
SAT-416 The impact of SGLT-2i and GLP-1RA on liver-related events in patients with metabolic dysfunction-associated steatotic liver disease: a systematic review and network meta-analysis
Authors: Lu Li, Ka Shing Cheung, Xianhua Mao, Lung-Yi Mak, Rex Wan-Hin Hui, Man-Fung Yuen, Wai-Kay Seto
Journal: Journal of Hepatology (2025)
SAT-029 Hepatitis C incidence in Pakistan – large scale test and recall analysis shows that infection rates can be reduced by pro-active 'find and treat’ programs
Authors: Saad Niaz, Saeed Sadiq Hamid, Asad Chaudhry, Naheed Choudhry, Graham R Foster, HepFreePak Consortium, Huma Qureshi
Journal: Journal of Hepatology (2025)
WED-229-YI Prognostic performance of MELD 3.0 in patients undergoing transjugular intrahepatic portosystemic shunt placement - a retrospective multicentre study
Authors: Markus Kimmann, Dominik Bettinger, Johannes Chang, Roman Kloeckner, Nancy Farouk, Ahmad Shikh Mousa, Silvia Letmathe, Feras Sanoubara, Juliana Goediker, Jörn Arne Meier, Zeyu Wang, Karel Caca, Hauke Heinzow, Leon Louis Seifert, Lukas Sturm, Karl Heinz Weiss, Christian Rupp, Franziska Weppelmann, Sara Noemi Reinartz Groba, Frank Erhard Uschner, Gesa Pöhler, Michael Köhler, Max Masthoff, Martin Rössle, Felix Piecha, Johannes Kluwe, Alexander Zipprich, Christian Jansen, Carsten Meyer, Michael Schultheiß, Jonel Trebicka, Michael Praktiknjo
Journal: Journal of Hepatology (2025)
THU-019 Gaps in palliative care for liver cirrhosis in Singapore: an analysis on disease burden, timing and utilization of palliative services
Authors: Charlene Yeo Li Xin, Lionel See Kee Yon, Grace Yang, Charlene Tan Hui Min, Su Qiqi, Tay Pei Yoke, Aiden Lin Yuda, Jolyn Tan Yi Ling, Koh Guan Hong, Loh Soak Yee, Lim Qian Hui, Marianne DeRoza
Journal: Journal of Hepatology (2025)
SAT-404 Accuracy of non-invasive tools in excluding advanced fibrosis in Wilson disease: results from the Wilson disease registry and Barcelona cohorts
Authors: Zoe Mariño, Uyen Kim To, Isabelle Mohr, Regino González-Peralta, Sanjiv Harpavat, Sihoun Hahn, Thomas Damgaard Sandahl, Asim Ulcay, Hatice Maras, Sefa Keserci, Kaitlin Maciejewski, Yanhong Deng, Michael Schilsky
Journal: Journal of Hepatology (2025)
WED-422 The diagnostic ability for hepatic steatosis byattenuation imaging using MRI-PDFF as reference standard; a prospective multicenter study in Japan
Authors: Takashi Nishimura, Hiroko Iijima, Toshifumi Tada, Tomoyuki Akita, Reiichiro Kondo, Yasuaki Suzuki, Kento Imajo, Shigehiro Kokubu, Tamami Abe, Hidekatsu Kuroda, Masashi Hirooka, Yoichi Hiasa, Asako Nogami, Atsushi Nakajima, Sadanobu Ogawa, Hidenori Toyoda, Satoshi Oeda, Hirokazu Takahashi, Yuichiro Eguchi, Katsutoshi Sugimoto, Hirohisa Yano, Junko Tanaka, Fuminori Moriyasu, Masayoshi Kage, Takashi Kumada
Journal: Journal of Hepatology (2025)
WED-167 The efficacy of HCP407 in reducing dysphagia and chest pain following esophageal variceal ligation in patients with cirrhosis. Preliminary results of a prospective randomized study
Authors: Alejandro Fernandez-Simon, Joan Sampons, Clàudia García-Solà, Alex Bofill, Andres Cardenas
Journal: Journal of Hepatology (2025)
FRI-045-YI Hepatic stellate cells orchestrate the retention and functional impairment of tissue-resident CD8+ T-cells in the fibrotic human liver
Authors: George Finney, Stephanie Kucykowicz, Daniel Brown Romero, Bethany H. James, Ginevra Pistocchi, Anandita Mathur, Niamah Nishan, Giulia Lupo, Maria Castanho Martins, Walid Al-Akkad, Mala Maini, Prakash Ramachandran, Krista Rombouts, Laura J. Pallett
Journal: Journal of Hepatology (2025)
FRI-336-YI Genetic variation in GPAM and protection against histologic severity in metabolic dysfunction-associated steatotic liver disease
Authors: Aaron Hakim, Tae-Hwi Linus Schwantes-An, Callie Zaborenko, Marco Abreu, Xiuqing Guo, Jie Yao, Jingyi Tan, Luca Lotta, Niek Verweij, Naga Chalasani
Journal: Journal of Hepatology (2025)
FRI-415 The mGluR5 blockade by MPEP inhibits PKC and triggers AMPK activation reducing hepatic steatosis in vitro
Authors: Michelangelo Trucchi, Laura Giuseppina Di Pasqua, Francesca Protopapa, Sofia Lotti, Anna Cleta Croce, Mariapia Vairetti, Ferdinando Nicoletti, Andrea Ferrigno
Journal: Journal of Hepatology (2025)
Integration of gene mutations in risk prognostication for watch‐and‐wait follicular lymphoma patients initiating first‐line treatment
Authors: Tian‐Yuan Xu, Rong‐Ji Mu, Hui‐Lai Zhang, Bing Xu, Rong Li, Nan Wang, Rui Sun, Rui‐Chi Li, Di Fu, Xian‐Huo Wang, Zhi‐Feng Li, Yan Zhao, Peng‐Peng Xu, Shu Cheng, Li Wang, Wei Tang, Zhong Zheng, Wei‐Li Zhao
Journal: HemaSphere (2025)

Abstract Follicular lymphoma (FL) patients with low tumor burden at diagnosis frequently undergo the watch‐and‐wait (W&amp;W) strategy. The study aimed to facilitate risk assessment in predicting the time to lymphoma treatment (TLT) for W&amp;W patients through an integrated analysis of clinical factors and genetic mutations. A retrospective study was conducted on 214 FL patients managed with W&amp;W between 2016 and 2023. Among them, 184 patients underwent targeted sequencing. The median follow‐up was 30.4 months (IQR 21.4–41.9, range 6.4–95.8). A clinico‐genetic model m3‐PRIMA‐PI was developed using the multivariate Cox proportional hazards method, incorporating two clinical parameters (bone marrow involvement and elevated β2‐MG) and three gene mutations ( KMT2D , EP300 , and TP53 ). Patients were categorized into low (69.0%), intermediate (21.7%), and high (9.2%) risk groups. Probabilities of treatment initiation at one year were 11.0% (95% CI, 5.2%–16.5%), 26.0% (95% CI, 10.7%–38.7%), and 54.3% (95% CI, 22.3%–73.1%); and at 2 years were 29.4% (95% CI, 20.2%–37.5%), 49.8% (95% CI, 31.1%–63.4%), and 93.5% (95% CI, 56.7%–99.0%), respectively. The predictive performance for TLT was superior with m3‐PRIMA‐PI, achieving a C‐index of 0.66 (95% CI, 0.63–0.69), compared to established indexes like FLIPI (C‐index 0.59, 95% CI, 0.56–0.62) and FLIPI2 (C‐index 0.59, 95% CI, 0.55–0.61). The above results were further validated in an independent external cohort. The m3‐PRIMA‐PI may provide a promising tool for risk stratification in W&amp;W FL patients.
FRI-341 miRNA isoforms are differentially expressed with increasing disease activity and fibrosis in metabolic dysfunction-associated steatotic liver disease
Authors: Christian Brion, Stephen Hoang, Guangliang Wang, Faridoddin Mirshahi, Jessie Ang, Matthew Long, Zheng Zhu, Bhanu Sakhamuri, Molly Srour, Mohammad Siddiqui, Amon Asgharpour, Neal Foster, David Salzman, Arun J. Sanyal
Journal: Journal of Hepatology (2025)
TOP-443 Paneth cells regulate intestinal lymphangiogenesis and lipid metabolism in metabolic dysfunction-associated steatotic liver disease
Authors: Oriol Juanola, Nathalie Coutry, Marco Felber, Bahtiyar Yilmaz, Elisa Sorrenti, Giandomenica Iezzi, Fabienne Birrer, Tural Yarahmadov, Reiner Wiest, Deborah Stroka, Philippe Jay, Andrea de Gottardi, Sheida Moghadamrad
Journal: Journal of Hepatology (2025)
WED-429 The utility of noninvasive tests - LIVERFASt, FIB4 and vibrationcontrolled transient elastography (VCTE, Fibroscan) - in the initiation and monitoring of the therapy with TNR-beta agonist (resmetirom) in MASH patients
Authors: Jeevin Sandhu, Shaheen Mehrara, Mona Munteanu, Mangesh Pagadala, Ashwini Mehta, John Lee, Parvez Mantry
Journal: Journal of Hepatology (2025)
WED-103 Impact of statin therapy on survival in hepatocellular carcinoma: a single-center study
Authors: Konstantinos Papantoniou, Efthymios Tsounis, Evangelia Bourdalou, Nikitas Kimiskidis, Georgios Geramoutsos, Ploutarchos Pastras, Ioanna Aggeletopoulou, Odysseas Ampazis, Georgia Diamantopoulou, Tryphon Spyridonidis, Konstantinos Katsanos, Konstantinos Thomopoulos, Christos Triantos
Journal: Journal of Hepatology (2025)
FRI-480-YI Changes in sarcopenia and adipose tissue alterations do not predict post-transplant outcomes in patients with cirrhosis and hepatocellular carcinoma undergoing liver transplantation
Authors: Francesca D’Arcangelo, Margherita Marchiori, Jacopo Lanari, Alberto Ferrarese, Martina Gambato, Salvatore Piano, Giacomo Germani, Francesco Paolo Russo, Marco Senzolo, Paolo Angeli, Umberto Cillo, Patrizia Burra, Alberto Zanetto
Journal: Journal of Hepatology (2025)
FRI-179 Integrated analyses of cytokine and metabolomics profiles uncover pathways regulating acute-on-chronic liver failure induced mortality
Authors: Yuexiang Bian, Jinjun Chen, Guohong Deng, Xin Zheng, Yan Huang, Xian-Bo Wang, Peixuan Ji, Jianyi Wei, Yan Zhang, Wenyi Gu, Adila Abuduaini, Kai He, Yawen Lu, Lining Guo, Hai Li
Journal: Journal of Hepatology (2025)
THU-114 Liposomal doxorubicin and atezolizumab promote EMT regression by acting on the tumor microenvironment: preclinical in vitro and in vivo studies
Authors: Ilaria Zanotto, Daniela Gabbia, Antonella Grigoletto, Margherita Toffanin, Maria Calienni, Gianfranco Pasut, Sara de Martin
Journal: Journal of Hepatology (2025)
SAT-321 Immunological correlates of rapid HBsAg decline in chronic HBV hepatitis patients undergoing Tenofovir Amibufenamide treatment
Authors: Shu Xiong, Hang Jia, Xu Quan, Bo Liang, Si Lu, Yi Cheng, Hua Wang, Han Li, Ling Xu, Su Li, Tong Wang, Yi Shu, Jia Yu, Jia Liu, Xin Zheng
Journal: Journal of Hepatology (2025)
SAT-245 Treatment duration, adherence and persistence in patients with chronic hepatitis B virus infection treated with long-term nucleos (t)ide analogues in Germany
Authors: Verena Königer, Simon Hohenester, Vera Gielen, Seth Anderson, Tim Hartmann, Marlene Rohrmann, Tammo Viering, Svitlana Schnaidt, Shayon Salehi, Christian Jacob, Afisi Ismaila
Journal: Journal of Hepatology (2025)