SOME QUANTITATIVE ASPECTS OF TREATMENT WITH QUINIDINE
Authors: M SOKOLOW
Journal: Annals of Internal Medicine (1956)

Article1 October 1956SOME QUANTITATIVE ASPECTS OF TREATMENT WITH QUINIDINEMAURICE SOKOLOW, M.D., F.A.C.P.MAURICE SOKOLOW, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-45-4-582 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptEven a cursory review of the literature will make it clear that there is great variability in the use and dosage of quinidine in this country. Opinion differs greatly as to the value of the drug, and the concepts of the risks involved vary from one medical center to another. This state of affairs is true even though the drug has been used rather abundantly in the past 35 years. In the present communication we hope to reconcile some of these differences and to summarize some of our work, where the emphasis in the use of quinidine has been placed...Bibliography1. Fahr G: Treatment of cardiac irregularities, J. A. M. A. 111: 2268, 1938. CrossrefGoogle Scholar2. BrodieUdenfriend BBS: Estimation of quinine in human plasma, with note on estimation of quinidine, J. Pharmacol. and Exper. Therap. 78: 154, 1943. Google Scholar3. SokolowBall MRE: Factors influencing the conversion of chronic auricular fibrillation, with special reference to serum quinidine concentration, Circulation, in press. Google Scholar4. SweetSokolow NJM: Studies with parenteral quinidine, in preparation. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: San Francisco, California*Presented at the Thirty-seventh Annual Session of The American College of Physicians, Los Angeles, California, April 17, 1956.From the Department of Medicine, University of California School of Medicine, San Francisco, California.†Aided in part by grants from the Placer County, California, and the San Francisco Heart Associations.Requests for reprints should be addressed to Maurice Sokolow, M.D., Associate Professor of Medicine, University of California School of Medicine, San Francisco, California. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byGeometric Understanding of Local Fluctuation Distribution of Conduction Time in Lined-Up Cardiomyocyte Network in Agarose-Microfabrication Multi-Electrode Measurement AssayRole of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidineComplications cardiovasculaires des convulsions au cours des intoxications par antidépresseurs cycliquesTherapy of refractory symptomatic atrial fibrillation and atrial flutter: a staged care approach with new antiarrhythmic drugsVentricular arrhythmias: Why is it so difficult to find a pharmacologic cure?HerzrhythmusstörungenClinical pharmacokinetics of antiarrhythmic drugsManagement of the Patient with a Prosthetic Heart ValvePharmacologic therapy of ventricular arrhythmiasCardiac Function in Patients Treated with Phenothiazines. Comparison with QuinidineTachyarrhythmias in Myocardial InfarctionClinical evaluation of antiarrhythmic drugsPharmacodynamics and clinical use of cardiovascular drugs after cardiac surgeryIncreased Survival with Prophylactic Quinidine After Experimental Myocardial InfarctionManagement of patients with atrial fibrillationCardioversion of Atrial FibrillationThe clinical pharmacology and use of quinidine in heart diseaseVentricular TachycardiaThe management of chronic atrial fibrillation: Indications for and method of conversion to sinus rhythm 1 October 1956Volume 45, Issue 4Page: 582-588KeywordsAtrial fibrillationAttentionDrugsHeartStenosis ePublished: 1 December 2008 Issue Published: 1 October 1956 PDF downloadLoading ...