tbuckley/cabot-search huggingface dataset:
TCTAP A-060 Contrasting Prognostic Value of Discordance Between Fractional Flow Reserve and Resting Distal-to-aortic Coronary Pressure Ratio in Coronary Lesion
Authors: Somin Lim, Jung-Min Ahn, Ha Hye Jo, Joongmin Lee, Jinho Lee, Yeonwoo Choi, Hoyun Kim, Sang Yong Jo, Do-Yoon Kang, Duk-Woo Park, Seung-Jung Park
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-079 A Case of Triple Vessel Disease (Distal LMT, Ostial LAD CTO, Proximal RCA and LCX Stenosis) With Poor Left Ventricular Function Deemed Unfit for CABG Underwent Full Revascularization by Complex PCI
Authors: Hou Tee Lu, Azrina Abdul Kadir, Heng Shee Kim, Chu Zhen Quek, Yu Ying Ong, Vicknesan Kulasingham, Mahadevan Gurudevan
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-155 Ultra Low Contrast Percutaneous Coronary Intervention in Patient of Acute Coronary Syndrome With Renal Failure
Authors: Citra Dewi Wahyu Fitria, Doni Firman, Amir Aziz Alkatiri, Arwin Saleh Mangkuanom, Nanda Iryuza
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-041 Long Term Effect of Treatment in Patients With Carotid Angioplasty and Stenting In-Stent Restenosis
Authors: Sheng-Fu Liu, Ying-Hsien Chen, Mao-Shin Lin, Ching-Chang Huang, Chih-Fan Yeh, Cheng-Hsuan Tsai, Hsien-Li Kao
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-055 Echocardiographic Pressure Half Time (PHT) for Evaluation of Pulmonary Regurgitation in Patients With Repaired Tetralogy of Fallot (rTOF): A Systematic Review and Meta-Analysis
Authors: Nindya Permata Bunda Surya Utami, Fadhilah Harmen, Muammar Emir Ananta, Nayla Karima, Rina Ariani, Radityo Prakoso, Yovi Kurniawati
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-005 Proper Sizing Takes into Consideration of Annular and Supra-Annular Planes and Calcium Distribution Can Improve Outcomes of Transcatheter Aortic Valve Replacement With Both Balloon-Expandable and Self-Expanding Valves
Authors: Wei-Hsian Yin, Yung-Tsai Lee, Kuo Chen Lee, Tien Ping Tsao, Jeng Wei
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-212 Valve-In-Valve TAVR in a Patient of Degenerated Trifecta-21 With Severe Aortic Regurgitation and History of Implantation of AAA Stent Graft for Abdominal Aortic Aneurysm
Authors: Debdatta Bhattacharyya, Manik Chopra, Snehil Goswami
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-146 Drug Coated Balloon in de Novo Lesion of Large Coronary Vessel Lesion, Ostial Left Anterior Descending Artery (LAD): Should We Use It More?
Authors: Jin Kiang Cheng, Wee Pang Ng, Mahadevan Gurudevan, Azrina Abdul Kadir, Jian Hao Sim, Richard Chay Shien Long
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-052 I See, I Stream and I Conquer: A Case of IVUS Guided 3D Rewiring of RCA CTO-ISR
Authors: Heng Shee Kim, Vicknesan Kulasingham, Hou Tee Lu, Mahadevan Gurudevan, Anek Kanoksilp
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-008 Predilatation Before Stenting Versus Direct Stenting in Patients Presenting With St-Elevation Myocardial Infarction and Managed by Primary Percutaneous Coronary Intervention
Authors: Walid Jomaa, Taha Lassoued, Hajer Farhat, Ikram Chamtouri, Ahmed Turki, Khaldoun Ben Hamda
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-148 Case Report: Successful Revascularization of de Novo Chronic Total Occlusion Lesion With Drug Coating Balloon
Authors: Wee Pang Ng, Jin Kiang Cheng, Jian Hao Sim, Richard Chay Shien Long, Wen Sheng Wong, Azrina Abdul Kadir, Gurudevan Mahadevan, Kim Fong Ng
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-059 Long Term Clinical Outcome After Myocardial Revascularization for Multivessel Coronary Disease in Patients With Left Ventricular Dysfunction
Authors: Hansu Park, Hoyun Kim, Jinho Lee, Yeonwoo Choi, Do-Yoon Kang, Jung-Min Ahn, Seung-Jung Park, Duk-Woo Park
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-026 Clinical and Angiographic Factors Associated With Success of Percutaneous Coronary Intervention in Chronic Total Occlusion: Insights From a Single-Center Experience in a Developing Country
Authors: Primasitha Maharany Harsoyo, Ariikah Dyah Lamara, Hanestya Oky Hermawan, Yudi Her Oktaviono
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-014 Postdilatation After Stent Deployment During Primary Percutaneous Coronary Intervention: A Systematic Review and Meta-Analysis
Authors: Teuku Muhammad Haykal Putra, Wishnu Aditya Widodo, Bayushi Eka Putra, Sunarya Soerianata, Achmad Fauzi Yahya, Jack Wei Chieh Tan
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-034 Clinical Outcomes of Vessels With Discordant Physiology and Imaging-Criteria for Percutaneous Coronary Intervention
Authors: Seokhun Yang, Doyeon Hwang, Jinlong Zhang, Eun-Seok Shin, Chang-Wook Nam, Joon-Hyung Doh, Jian-An Wang, Hitoshi Matsuo, Takashi Kubo, Tsunekazu Kakuta, Bon-Kwon Koo
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-015 Clinical Insights: Impact of BMI and Gender on Postoperative Myocardial Ischemia Following Remote Ischemic Preconditioning in Cardiac Surgery - A Meta-Regression Analysis
Authors: Ameer Fadhil Abbas Al Wssawi, Armand Gumera, Ahmed Ibrahim, Hashim Talib Hashim, Ali Saad Al-shammari, Ghadeer Mohammed Abbas, Mohannad Gamal Abdeltawwab, Mahmoud Amim, Urooj Shamim, Mohanad Alchamaley
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-048 Impact of Minimal Invasive Extracorporeal Circulation in Coronary Artery Bypass Surgery: Meta-Analysis
Authors: Ameer Fadhil Abbas Al Wssawi, Armand Gumera, Ali Saad Al-Shammari, Hasnaa Abdelsamad, Hashim Talib Hashim
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-044 Prognostic Impact of Geriatric Nutritional Risk Index After Endovascular Treatment With Lower Extremity Artery Disease
Authors: Akinori Satake, Toru Niwa, Masahiro Shimoda, Akihiro Suzuki, Yusuke Nakano, Hirohiko Ando, Tetsuya Amano
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-209 Emergency Transcatheter Aortic Valve Implantation Under Extracorporeal Membrane Oxygenation for Cardiogenic Shock due to a Bicuspid Aortic Stenosis With Large Annulus
Authors: Shinnosuke Nomura, Shuhei Tsuji, Junichi Tazaki, Mamoru Toyofuku
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-028 Revolution Through 3D-Wiring: Tip Detection-Antegrade Dissection and Reentry With New Puncture Wire in Chronic Total Occlusion Intervention
Authors: Kota Tanaka, Atsunori Okamura, Mutsumi Iwamoto, Satoshi Watanabe, Tomohiro Yamasaki, Akinori Sumiyoshi
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-013 Clinical Outcomes of ST Segment Resolution Following Primary Percutaneous Coronary Intervention
Authors: Khaled Shunnar, Alaa Rahhal, Mhd Baraa Habib, Mohammad Altermanini, Yousef Mohammed Ali Hailan, Mohammad AlKhateeb, Mohamed Salah Abdelghani, Osama Nweiran AlKhalaila, Mohanad Jamal Shehadeh, Abdul Rahman Arabi
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-018 The Utilization of Quantitative Flow Ratio (QFR) Study for Decision in Percutaneous Coronary Intervention and Outcomes
Authors: Samshol Sukahri, Imran Zainal Abidin, Wan Azman Wan Ahmad, Ahmad Syadi Mahmood Zuhdi, Kok Han Chee, Ramesh Singh Argan Singh, Alexander Loch, Nor Ashikin Md Sari, Syuhada Khairul Anuar, Kee Wei Lee, Muhammad Azlan Aseri, Mohamad Rodi Isa
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-162 Angiography Derived 3D Physiologic Mapping of the Coronary Flow Using QFR for the Planning of the Complex PCI
Authors: Oyunkhand Buyankhishig, Gereltuya Choijiljav, Damdinjav Enkhee, Bum-Erdene Batbayar, Surenjav Chimed, Batzaya Tsognemekh, Erdembileg Dandar, Khuyag Batmyagmar
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-052 Pursuing Cardiology Specialty as a Career: Perspectives From Iraqi Medical Students
Authors: Zahraa Sattar Jassim, Saja AbdulHamza AbdulHassan, Esraa Hwaish Flayyih, Rabab Huwaish Flayyih, Zainab Dakhil
Journal: Journal of the American College of Cardiology (2024)
TCTAP A-036 Comparison of Angiography Derived 3D Physiologic Mapping Between Intravascular Ultrasound Versus Angiography Guided Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease
Authors: Erdembileg Dandar, Oyunkhand Buyankhishig, Bum-Erdene Batbayar, Gereltuya Choijiljav, Batzaya Tsognemekh, Damdinjav Enkhee, Surenjav Chimed, Batmyagmar Khuyag
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-130 Recurrent Cardiac Tamponade After Rotablator-Associated Coronary Perforation Treated With Additional Covered Stent Implantation
Authors: Koichiro Hori, Shunsuke Matsuno, Mayu Sakuma, Mikio Kishi, Hiroto Kano, Yuji Oikawa, Junji Yajima
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-037 Leopard Crawl Technique in Retrieval of Entrapped Side Branch Wire in Calcified, Bifurcation Lesion
Authors: Neerusha Kaisbain, Chong Wei Loong, Chew Fui Lo, Khoo Song Weng Ryan, Houng Bang Liew
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-128 Iatrogenic Aorto-Coronary Dissection During CTO PCI Right Coronary Artery in Post-CABG Patient
Authors: Vimean Sey, Doni Firman, Amir Aziz Alkatiri, Arwin Saleh Mangkuanom, Nanda Iryuza
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-160 Double-Edged Sword Situation in a Post-PCI Patient: A Case Report
Authors: Abeeda Tasnim Reza, Kazi Atiqur Rahman, Shahab Uddin Talukder, A.Q.M. Reza, AHM Waliul Islam, Aparajita Karim, Poppy Bala, Azfar Hossain Bhuiyan, Sadeed Araf Reza
Journal: Journal of the American College of Cardiology (2024)
American College of Rheumatology and Food and Drug Administration Summit: Summary of the Meeting, May 17–18, 2022
Authors: Jonathan Kay, Nikolay P. Nikolov, Michael H. Weisman
Journal: Arthritis & Rheumatology (2024)

The American College of Rheumatology and the US Food and Drug Administration co-sponsored a public meeting in May 2022 about challenges in the clinical development of drugs for rheumatoid arthritis (RA) and psoriatic arthritis (PsA), focusing on innovative clinical trial designs, outcome measures, and data collection methods. Recommendations include early dose-ranging studies and use of active comparators. Challenges and opportunities in assessing long-term safety by leveraging real-world data from electronic health records (EHRs) and claims data are discussed, along with insights from European registries and the evolving role of real-world evidence and artificial intelligence in regulatory evaluations. Endpoints for assessing disease activity and outcome measures used in RA and PsA trials are explored, emphasizing challenges in defining remission, assessing clinical response, and evaluating structural progression. The need for outcome measures that better reflect treatment targets and the potential of advanced imaging in future trials are highlighted. Challenges with placebo-controlled trials in RA are discussed and use of non-inferiority clinical trial design, in which new drugs are evaluated with active comparators, is proposed. Pragmatic trials in RA and PsA, employing decentralized approaches, are highlighted for their real-world relevance and administrative efficiencies. Strategies for identifying at-risk populations for RA and the challenges of using EHRs and insurance claims data in drug development are discussed. Registry data and digital health technologies show promise in bridging the gap between clinical trials and real-world effectiveness.
TCTAP C-073 Chronic Total Occlusion Intervention in a Young, Obese Patient With End Stage Renal Disease: Scraping Through by the Skin of Our Knuckles
Authors: Noor Diyana binti Mohamad Farouk, Hamat Hamdi Che Hassan, Boon Cong Beh, Mohd Asyiq Al-Fard Bin Mohd Raffali, Shawal Faizal Mohamad, Rosli Mohd Ali
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-008 A Management Dilemma: Case of Coronary Artery Ectasia Presenting as ST Segment Elevation Acute Myocardial Infarction in a 56- Year- Old Male
Authors: Ma Victoria Collantes Fernandez, Marrafe Correa, Meliton III Aquines Evangelista, Ronald Santos, Philipp C. Ines
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-095 A Rare Case Report: Floating Wire Technique in Isolated Ostial Left Main Coronary Artery Disease
Authors: Adriyawan Widya Nugraha, Arief Wibisono, Evit Ruspiono, Tri Astiawati, Fitranti Suciati Laitupa
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-179 A Glimpse of Light at the End of Tunnel
Authors: Huan Yean Kang, Kai Soon Liew, Vijayendran Rajalingam, Yuen Hoong Phang, Kenneth Kay Leong Khoo, Aditya Fahmi Prianda, Chai Yih Tan, Kamtha Rao Narasamuloo, Saravanan Krishinan, Chee Tat Liew, Dharmaraj Karthikesan
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-038 Overcoming Left Main Bifurcation Lesion With Nodular Calcification Using Rota-Cut Strategy
Authors: Akara Kijnithikul, Sakolwat Montrivade, Sukhum Tachasakunjaroen, Wasant Soonfuang, Anuruck Jeamanukoolkit
Journal: Journal of the American College of Cardiology (2024)
TCTAP C-142 Successful Percutaneous Coronary Intervention of Catheter Induced Type F Coronary Artery Dissection With Subintimal Tracking and Re-Entry Technique
Authors: Chong Wei Loong, Khoo Song Weng Ryan, Chew Fui Lo, Neerusha Kaisbain, Houng Bang Liew
Journal: Journal of the American College of Cardiology (2024)
Dual-centre evaluation of the FluoroType MTBDR version 2 assay for detection of Mycobacterium tuberculosis complex and resistance-conferring mutations in pulmonary and extrapulmonary samples from Denmark, Germany and Sierra Leone
Authors: Erik Svensson, Hannah Ketelsen, Sönke Andres, Dorte Bek Folkvardsen, Doris Hillemann, Ousman Conteh, Anders Norman, Stefan Niemann, Troels Lillebaek, Martin Kuhns
Journal: Clinical Microbiology and Infection (2024)
Single cell analysis unveils B cell-dominated immune subtypes in HNSCC for enhanced prognostic and therapeutic stratification
Authors: Kang Li, Caihua Zhang, Ruoxing Zhou, Maosheng Cheng, Rongsong Ling, Gan Xiong, Jieyi Ma, Yan Zhu, Shuang Chen, Jie Chen, Demeng Chen, Liang Peng
Journal: International Journal of Oral Science (2024)

Abstract Head and neck squamous cell carcinoma (HNSCC) is characterized by high recurrence or distant metastases rate and the prognosis is challenging. There is mounting evidence that tumor-infiltrating B cells (TIL-Bs) have a crucial, synergistic role in tumor control. However, little is known about the role TIL-Bs play in immune microenvironment and the way TIL-Bs affect the outcome of immune checkpoint blockade. Using single-cell RNA sequencing (scRNA-seq) data from the Gene Expression Omnibus (GEO) database, the study identified distinct gene expression patterns in TIL-Bs. HNSCC samples were categorized into TIL-Bs inhibition and TIL-Bs activation groups using unsupervised clustering. This classification was further validated with TCGA HNSCC data, correlating with patient prognosis, immune cell infiltration, and response to immunotherapy. We found that the B cells activation group exhibited a better prognosis, higher immune cell infiltration, and distinct immune checkpoint levels, including elevated PD-L1. A prognostic model was also developed and validated, highlighting four genes as potential biomarkers for predicting survival outcomes in HNSCC patients. Overall, this study provides a foundational approach for B cells-based tumor classification in HNSCC, offering insights into targeted treatment and immunotherapy strategies.
Automated and Personalized Outreach to Level the Playing Field for Colorectal Cancer Screening
Authors: Alexa L. Pohl, Arden M. Morris
Journal: JAMA Network Open (2024)

Clara Podmore, MD, MPhil, PhD; Kevin Selby, MD, MAS; Christopher D. Jensen, PhD, MPH; Wei K. Zhao, MPH; Noel S. Weiss, MD, DrPH; Theodore R. Levin, MD; Joanne Schottinger, MD; Chyke A. Doubeni, MD, MPH; Douglas A. Corley, MD, PhD, MPH
Errors in the Results
Journal: JAMA Network Open (2024)

Children With aMental Health Condition Between 2017 and 2021," 1 published March 11, 2024, there was a typo in a percentage in the Results section regarding the increase in pediatric mental health care costs from 2017 to 2021.The original percentage stated it was a 31.1% increase, but it was a 45.2% increase.
Tetrahedral framework nucleic acids/hyaluronic acid-methacrylic anhydride hybrid hydrogel with antimicrobial and anti-inflammatory properties for infected wound healing
Authors: Cai Qi, Qiang Sun, Dexuan Xiao, Mei Zhang, Shaojingya Gao, Bin Guo, Yunfeng Lin
Journal: International Journal of Oral Science (2024)

Abstract Bacterial resistance and excessive inflammation are common issues that hinder wound healing. Antimicrobial peptides (AMPs) offer a promising and versatile antibacterial option compared to traditional antibiotics, with additional anti-inflammatory properties. However, the applications of AMPs are limited by their antimicrobial effects and stability against bacterial degradation. TFNAs are regarded as a promising drug delivery platform that could enhance the antibacterial properties and stability of nanodrugs. Therefore, in this study, a composite hydrogel (HAMA/t-GL13K) was prepared via the photocross-linking method, in which tFNAs carry GL13K. The hydrogel was injectable, biocompatible, and could be instantly photocured. It exhibited broad-spectrum antibacterial and anti-inflammatory properties by inhibiting the expression of inflammatory factors and scavenging ROS. Thereby, the hydrogel inhibited bacterial infection, shortened the wound healing time of skin defects in infected skin full-thickness defect wound models and reduced scarring. The constructed HAMA/tFNA-AMPs hydrogels exhibit the potential for clinical use in treating microbial infections and promoting wound healing.
The estrogen signaling pathway reprograms prostate cancer cell metabolism and supports proliferation and disease progression
Authors: Camille Lafront, Lucas Germain, Gabriel H. Campolina-Silva, Cindy Weidmann, Line Berthiaume, Hélène Hovington, Hervé Brisson, Cynthia Jobin, Lilianne Frégeau-Proulx, Raul Cotau, Kevin Gonthier, Aurélie Lacouture, Patrick Caron, Claire Ménard, Chantal Atallah, Julie Riopel, Éva Latulippe, Alain Bergeron, Paul Toren, Chantal Guillemette, Martin Pelletier, Yves Fradet, Clémence Belleannée, Frédéric Pouliot, Louis Lacombe, Éric Lévesque, Étienne Audet-Walsh
Journal: Journal of Clinical Investigation (2024)

Just as the androgen receptor (AR), the estrogen receptor α (ERα) is expressed in the prostate and is thought to influence prostate cancer (PCa) biology. Yet, the incomplete understanding of ERα functions in PCa hinders our ability to fully comprehend its clinical relevance and restricts the repurposing of estrogen-targeted therapies for the treatment of this disease. Using two human PCa tissue microarray cohorts, we first demonstrated that nuclear ERα expression was heterogeneous among patients, being only detected in half of tumors. Positive nuclear ERα levels were correlated with disease recurrence, progression to metastatic PCa, and patient survival. Using in vitro and in vivo models of the normal prostate and PCa, bulk and single-cell RNA-Seq analyses revealed that estrogens partially mimic the androgen transcriptional response and induce specific biological pathways linked to proliferation and metabolism. Bioenergetic flux assays and metabolomics confirmed the regulation of cancer metabolism by estrogens, supporting proliferation. Using cancer cell lines and patient-derived organoids, selective estrogen receptor modulators, a pure anti-estrogen, and genetic approaches impaired cancer cell proliferation and growth in an ERα-dependent manner. Overall, our study revealed that, when expressed, ERα functionally reprograms PCa metabolism, is associated with disease progression, and could be targeted for therapeutic purposes.
Clinical phenotype of the <i>PIK3R1</i>-related vascular overgrowth syndrome
Authors: Paul Kuentz, Camille Engel, Mathieu Laeng, Martin Chevarin, Yannis Duffourd, Jéhanne Martel, Juliette Piard, Fanny Morice-Picard, Helene Aubert, Didier Bessis, Anne-Marie Guerrot, Annabel Maruani, Olivia Boccara, Juliette Mazereeuw-Hautier, Hagen Ott, Alice Phan, Eve Puzenat, Chloe Quelin, Christel Thauvin-Robinet, Laurence Faivre, Pierre Vabres
Journal: British Journal of Dermatology (2024)

Here we report 19 additional patients with PIK3R1 mosaic variants with clinical phenotyping, showing that the PIK3R1 phenotype is indistinguishable from the PIK3CA-related phenotypes, although the megalencephaly-capillary malformation phenotype is consistently absent in patients with PIK3R1 variants. We also report novel PIK3R1 variants. We consider that the meaning of PROS should shift from ‘PIK3CA-related overgrowth spectrum’ to ‘PI3-kinase-related overgrowth spectrum’.
Health‐related quality of life in transplant‐eligible patients with newly diagnosed multiple myeloma treated with daratumumab, lenalidomide, bortezomib, and dexamethasone: Patient‐reported outcomes from <scp>GRIFFIN</scp>
Authors: Rebecca Silbermann, Jacob Laubach, Jonathan L. Kaufman, Douglas W. Sborov, Brandi Reeves, Cesar Rodriguez, Ajai Chari, Luciano J. Costa, Larry D. Anderson, Nitya Nathwani, Nina Shah, Naresh Bumma, Sarah A. Holstein, Caitlin Costello, Andrzej Jakubowiak, Robert Z. Orlowski, Kenneth H. Shain, Andrew J. Cowan, Katharine S. Gries, Huiling Pei, Annelore Cortoos, Sharmila Patel, Thomas S. Lin, Peter M. Voorhees, Saad Z. Usmani, Paul G. Richardson
Journal: American Journal of Hematology (2024)

Abstract In the phase 2 GRIFFIN trial ( ClinicalTrials.gov identifier: NCT02874742), daratumumab added to lenalidomide, bortezomib, and dexamethasone (D‐RVd) improved depth of response and progression‐free survival (PFS) versus lenalidomide, bortezomib, and dexamethasone (RVd) alone in transplant‐eligible (TE) patients with newly diagnosed multiple myeloma (NDMM). Here, we present patient‐reported outcomes (PROs) collected using the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30‐item (QLQ‐C30), EORTC Quality of Life Questionnaire Multiple Myeloma Module 20‐item (QLQ‐MY20), and EuroQol 5‐Dimension 5‐Level (EQ‐5D‐5L) tools on day 1 of cycles 1, 2, and 3; on day 21 of cycle 4 (end of induction therapy); on day 1 of cycle 5; on day 21 of cycle 6 (end of posttransplant consolidation therapy); and at months 6, 12, 18, and 24 of maintenance therapy. Meaningful improvements from baseline were seen in most of the PRO scales with both treatments after consolidation and were sustained for at least 2 years of maintenance treatment. Large reductions from baseline (~20 points) were especially observed in pain symptoms for both treatment groups, although these were numerically higher for patients receiving D‐RVd during the majority of the time points. In addition, improvements in key scales, such as global health status, fatigue symptoms, and physical functioning, were also seen with both D‐RVd and RVd. These improvements in health‐related quality of life contribute to the totality of evidence supporting the improvement in clinical outcomes such as response rates and PFS with D‐RVd in induction, consolidation, and maintenance therapy in TE patients with NDMM.