A CASE OF CARCINOMA OF THE ISLANDS OF LANGERHANS WITH HYPOGLYCEMIA
Authors: Henry Joachim, Morris M. Banowitch
Journal: Annals of Internal Medicine (1938)

Case Reports1 March 1938A CASE OF CARCINOMA OF THE ISLANDS OF LANGERHANS WITH HYPOGLYCEMIAHENRY JOACHIM, M.D., F.A.C.P., MORRIS M. BANOWITCH, M.D., F. A. C. P.HENRY JOACHIM, M.D., F.A.C.P.Search for more papers by this author, MORRIS M. BANOWITCH, M.D., F. A. C. P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-9-1754 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe syndrome of spontaneous hypoglycemia described by Seale Harris1 was attributed by him to hyperinsulinism. Since then this conception has been amply confirmed by numerous reports in the literature, and particularly demonstrated by Wilder, Allan, Power and Robertson2 in 1927. They reported a case of carcinoma of the islands of Langerhans with liver and lymph node metastases, the extract of which was found capable of lowering the blood sugar in rabbits.In the past 10 years numerous cases of spontaneous hypoglycemia due to tumor formation have been reported but the great majority have been due to hyperfunctioning of adenomas of...References1. HARRIS S: Hyperinsulinism and dysinulinism, Jr. Am. Med. Assoc., 1924, lxxxiii, 729-733. CrossrefGoogle Scholar2. WILDERALLANPOWERROBERTSON RMFNMHHE: Carcinoma of the islands of the pancreas: hyperinsulinism and hypoglycemia, Jr. Am. Med. Assoc., 1927, lxxxix, 348-355. CrossrefGoogle Scholar3. HAMDI H: Ein insulargenetisches Pankreascarcinom (Insulom), Ztschr. f. Krebsforsch., 1932, xxxvii, 411-413. CrossrefGoogle Scholar4. JUDDFAUSTDIXON ESLSRK: Carcinoma of the islands of Langerhans with metastasis to the liver producing hyperinsulinism: report of case, West. Jr. Surg., 1934, xlii, 555-557. Google Scholar5. BICKELMOZERJUNET GJJR: Diabete avec denutrition grave: Disparition de la glycosurie et attenuation progressive de l'hyperglycemia à la suite du developpement d'un carcinoma insulaire du pancreas avec metastases hepatiques massives, Bull. et mém. Soc. med. d. hôp. de Paris, 1935, li, 12-21. Google Scholar6. CRAGGPOWERLINDEM RWMHMC: Carcinoma of the islands of Langerhans with hypoglycemia and hyperinsulinism, Arch. Int. Med., 1937, lx, 88-99. CrossrefGoogle Scholar7. HOWLANDCAMPBELLMALTBYROBINSON GWREJWL: Dysinsulinism: convulsions and coma due to islet cell tumor of the pancreas, with operation and cure, Jr. Am Med. Assoc., 1929, xciii, 674-679. CrossrefGoogle Scholar8. GRAHAMWOMACK EANA: The application of surgery to the hypoglycemic state due to islet tumors of the pancreas and to other conditions, Surg., Gynec. and Obst., 1933, lvi, 728-742. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, New York*Received for publication July 31, 1937. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byCarcinoma of the Islets of Langerhans with HyperinsulinismSpontaneous Hypoglycemia with Special Reference to the Diagnosis of HyperinsulinismTwo cases of spontaneous hypoglycemia due to a tumor of the islands of Langerhans 1 March 1938Volume 11, Issue 9Page: 1754-1759KeywordsAdenomasBlood sugarHyperinsulinemiaHypoglycemiaLiverLymph nodesRabbits ePublished: 1 December 2008 Issue Published: 1 March 1938 PDF downloadLoading ...