tbuckley/cabot-search huggingface dataset:
Psychosomatic Approach to Gynecology and Obstetrics
Authors: Fritz Wengraf
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Recent Advances in Medical Education in England.
Authors: Newman, George, Sir
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Handatlas der Cystoskopie.
Authors: Otto. Kneise
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Allogeneic Mesenchymal Stem Cells in Cellular Cardiomyoplasty: Mechanisms of Cardiac Repair
Authors: Konstantinos Hatzistergos
Journal: Circulation (2008)

Abstract 486 Konstantinos E. Hatzistergos, Henry Quevedo, Behzad N. Oskouei, Qinghua Hu, Ramesh Mazhari, Juan P. Zambrano, David Valdes, Gary S. Feigenbaum, Jose R. Rodriguez, Irene S. Margitich, Jeffrey M. Zimmet, Univ of Miami, Miami, FL; Concepción Revilla, INIA, Madrid, Spain; Alan W. Heldman, Ian McNiece, Joshua M. Hare, Univ of Miami, Miami, FL Konstantinos Hatzistergos, 2008 Finalist and Presenting Author
Orthopaedic Neurology. A Diagnostic Guide to Neurologic Levels.
Authors: Stanley Hoppenfeld, J. D. Hoppenfeld
Journal: Annals of Internal Medicine (1978)

Since its original publication, Orthopaedic Neurology: A Diagnostic Guide to Neurologic Levels has distinguished itself as a clearly written, uniquely focused text sought after by practitioners and trainees in orthopaedics, neurosurgery, physical medicine and rehabilitation, pain medicine, anesthesiology, neurology, and nursing, as well as primary care specialties. The second edition retains this standard of excellence while providing thorough updates in medical illustration, teaching techniques, and new approaches to the diagnosis and treatment of patients with spinal cord injuries. Now in vibrant full color, it offers a distinctive and practical combination of anatomy, the physical exam, and clinical pearls, highly readable and abundantly illustrated. Features: Discusses the diagnosis of neurologic levels according to common denominators, and combines them with the basic principles of neurology to assist in the appraisal of spinal cord and nerve root problems. Presents classic original drawings now carefully colorized for optimal visual reference, and additional drawings added as necessary. Corresponding radiographic imaging techniques (predominantly MRI and CT) have also been added. Each chapter first covers basic neurologic information, then provides clinical significance by applying it to the diagnosis of the more common neurologic pathologies. Ideal for those who wish to understand more clearly the clinical concepts behind neurologic levels, moving systematically from concept to practice, and from general rules to specific applications. Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac. Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time - providing a seamless reading experience online or offline Powerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooks Multiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive design The ability to highlight text and add notes with one click
Abstract 19241: Downregulation of microRNA-494 Facilitates Smooth Muscle Cell Proliferation and Vascular Remodeling
Authors: Katrin Donde, Jan-Marcus Daniel, Jochen Dutzmann, Johann Bauersachs, Daniel Sedding
Journal: Circulation (2014)

Introduction: Proliferation of vascular smooth muscle cells (VSMC) plays a crucial role in the development of vascular proliferative diseases such as atherosclerosis and in-stent-restenosis. MicroRNAs (miR) are small noncoding RNAs that modulate gene expression in a posttranscriptional manner. Hypothesis: in this project we aimed to determine the functional impact of a micro-RNA which is strongly regulated during vascular remodeling. Methods and Results: Neointima formation was induced by a wire-mediated injury of the femoral artery in C57BL/6 mice. Microarray analysis of the developing neointimal lesion showed a strong reduction of miR-494 (0.411±0.04) at 7 days after injury as compared to uninjured controls, which could be confirmed by qPCR. Interestingly, miR-494 was found to be predominantly expressed in SMC as determined by in situ hybridization. The regulation of miR-494 expression was further analyzed in vitro after stimulation of SMC with 10% FCS. Following this mitogenic stimulation, mir-494 expression dropped robustly and significantly in a time-dependent manner at 6, 9, and 24 hours. To investigate the functional impact of miR-494 on SMC proliferation, miR-494 was overexpressed using miR-494-mimics (20μM). Overexpression of miR-494 significantly reduced the FCS-induced proliferation of SMC as assessed by BrdU-incorporation and total cell counts. In silico analyses of potential target genes for miR-494 identified survivin, an important molecule for cell cycle regulation, as potential target of miR-494. Indeed, survivin was found down-regulated on the mRNA and protein level after transfection of SMC with miR-494 mimics and could be confirmed as direct target using luciferase reporter assays. Conclusions: Taken together, our results show that mir-494 is strongly down-regulated in proliferating SMC in vitro as well as during neointimal lesion formation in vivo. Moreover, the anti-proliferative effect of miR-494-reconstitution reveals a crucial functional role of miR-494 in the mitogenic response of SMC. Thus, miR-494 might represent a novel and promising SMC-specific target for future therapeutic strategies in the treatment of vascular proliferative diseases.
Abstract 2: Intra-arrest Induction of Therapeutic Hypothermia via Large-Volume Ice-Cold Saline Infusion Improves Immediate Outcomes for Out-of-Hospital Cardiac Arrest
Authors: John Freese
Journal: Circulation (2011)

Background: New York City Project Hypothermia is a collaborative effort involving the Fire Department of New York (FDNY), Greater New York Hospital Association, Health and Hospitals Corporation, the Regional Emergency Medical Advisory Committee, and the New York State Department of Health. As part of this effort, the FDNY implemented a pilot protocol in the New York City 9-1-1 System on August 1, 2010 that introduced the induction of therapeutic hypothermia during initial resuscitation efforts via large-volume ice-cold saline infusion. Purpose: We sought to assess the effects of this protocol on immediate survival end-points following out-of-hospital cardiac arrest (OOHCA). Methods: OOHCA data was analyzed for the following periods: August 1, 2009 - May 31, 2010 (historicalcontrol group) and August 1, 2010 - May 31, 2011 (study group). Except for the intra-arrest induction of hypothermia, no other aspect of the regional resuscitation protocols differed between the two periods. Standard Utstein definitions were utilized. Due to the large sample sizes, Chi-square analyses without Yates' correction were utilized, and a p &lt;0.05 was considered significant. Results: 5,582 resuscitations for nontraumatic adult cardiac arrests during the control period were compared to 4,727 resuscitations in the study period that included the intra-arrest induction of hypothermia. The groups did not differ with respect to age, response time, bystander witnessed status, or frequency of bystander CPR. Patients in the study period were less likely to be male (52.3% vs 54.6%, p = 0.019), less likely to be white (32.8% vs 35.1%, p = 0.013), and less likely to have an EMS-witnessed arrest (8.3% vs 9.5%, p=0.026). Return of spontaneous circulation (ROSC) and sustained ROSC were improved in the study group as compared to the control group: 31.7% vs 29.0% (p=0.003) and 24.1% vs 21.9% (p=0.0014), respectively. Conclusion: The initiation of therapeutic hypothermia via large volume, ice-cold saline infusion results in improved immediate survival for non-traumatic out-of-hospital cardiac arrest. To our knowledge, this is the first report to describe the use of intra-arrest hypothermia in humans and to demonstrate such an effect.
The quality of care: how can it be assessed?
Authors: A Donabedian
Journal: JAMA (1989)

<h3>To the Editor. —</h3> A critical problem in the schema of quality assessment described by Dr Donabedian<sup>1</sup>in his recent superb article lies in the area of measuring standards of care. With regard to technical aspects of care, the great time, effort, and expense needed to conduct studies from which generally accepted standards of care may be derived ensures that most clinical decisions are based on art rather than science. Furthermore, we live in an era of such rapid scientific and technological advances that study results may be outmoded by the time of publication. A kind of medical Heisenberg Uncertainty Principle exists: the act of deriving standards changes (advances) those standards. Therefore, technical aspects of care are difficult to measure and, when measured, are often inapplicable to assessing quality of care. Another method for establishing standards of quality technical care is that of consensus of experts. These standards, too,
Krebs und Vererbung
Authors: Hans R. Schinz, Franz Buschke
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Psychiatric Word Book: A Lexicon of Terms Employed in Psychiatry and Psychoanalysis Designed for Students of Medicine and Nursing and Psychiatric Social Workers
Authors: Richard Henry Hutchings
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Money and Freedom
Authors: Hans F. Sennholz
Journal: BMJ (1948)

Proposals to improve the system (any system) are a dime a dozen. Even at that price, they are in excess supply. This is particularly true of proposals to reform governmental institutions, and there is a good reason for it: “In government as in business we must try to set up institutions under which individuals who intend only their own gain are led by an invisible hand to serve the public interest.” The rub is that economists have only partially uncovered the workings of the invisible hand in government. The field of Public Choice is in its infancy. We may not like certain outcomes that our institutional arrangements produce, but until we understand how these institutions operate on the system of incentives facing government policymakers, any proposal for reform is no more than a shot in the dark. The little book by Hans F. Sennholz is an example, Sennholz is troubled by the apparent inflationary bias of our monetary system. Persistent inflation taxes money holding. A reduced quantity of real money balances is held, and there is a welfare cost associated with this (i.e., the costs imposed on money holders exceed the revenue generated by the tax). Although it is never clearly put, this welfare cost is the basis for Sennholz’s complaint. Most would agree that inflation is anettlesome problem. People can learn to live with it but they would rather be spared the lesson. Everyone prefers a low and stable rate of inflation if it can he achieved at the right price.2 Proposals to lick inflation are worthy of consideration if they are based on a careful analysis ofexisting monetary institutions so that we can identify the arrangements that induce policymakers to choose inflation over price stability. The analysis must indicate how the existing institution(s) can be altered to produce the desired results, Finally, it is important to compare estimates ofthe costs and benefits ofmaking the change. It maybe that theexisting set of monetary institutions is optimal even though they contain an inflationary bias. Sennholz does none of this in his book. Instead, he asserts that he has identified the offending institutions and that his alternative arrangements would produce net benefits. Without the analysis, however, the discussion strikes the reader as idle speculation. In Sennholz’s view, inflation is a natural consequence of the monopoly production of money by the government (p. 11). In the United States, the government’s agent is the Federal Reserve System, whose notes are granted legal tender status (pp. 14, 24, 27). Sennholz is never clear about whether
Virology and epidemiology; contributions in honor of John Rodman Paul.
Authors: Dorothy Millicent Horstmann
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tolerability of ongoing phase II study of concomitant radiation and docetaxel followed by docetaxel in prostate cancer patients with a persistent or rising PSA after radical prostatectomy
Authors: A. M. Harris, T. Y. Eng, A. B. Karnad, G. P. Swanson, C. Jenkins, R. Greene
Journal: Journal of Clinical Oncology (2009)

e16054 Background: Patients with a detectable PSA after radical prostatectomy (RRP) have persistent disease and inevitably succumb to disease as progression ensues. Radiation has been used in the salvage setting, but has only been found to cure less than half of these patients. SWOG 8794 has recently reported a significant increase in metastasis free survival in 15 years with adjuvant radiation for patients with high risk findings after RRP. It is of particular interest if adjuvant chemoradiation (CRT) can improve the rate of reaching a PSA nadir of zero after RRP in men with persistent or rising PSA. This ongoing IRB approved trial has thus far evaluated the tolerability of CRT utilizing the radiosensitizing agent Docetaxel (DX) for 7 weeks after RRP followed by adjuvant full dose DX (75mg/m2). Methods: Patients: Chemotherapy/hormone naïve, status post RRP, post-op PSA &gt; 0.2 ng/mL on two separate occasions, ECOG ≤ 2; treated with taxane-based chemotherapy (DX 20mg/m 2 weekly) concurrent with standard dose radiation for 7 weeks, and post-radiation chemotherapy DX (75mg/ m 2 ) given every 21 days for 4 cycles with premedication intravenous dexamethasone. Primary endpoint: Rate of PSA decline; Number of subjects reaching PSA nadir of zero. Secondary endpoints: Progression Free Survival (PFS) based on PSA progression, toxicity graded via Common Terminology Criteria for Adverse Events Version 3.0 (CTCAE), and overall survival (OS). Results: From 5/07 to 12/08, 16 pts with detectable PSA after RRP were treated; Median age 65 [48–74]; 16/16 completed CRT; 11/16 completed CRT and adjuvant DX; 3/16 dropped out due to adverse events after CRT; Toxicity: 19% (3/16) patients experienced Grade 3 toxicity during CRT and adjuvant DX; 29% (4/14) patients had Grade 3 toxicity during adjuvant DX; no Grade 4 toxicities. See Table . Conclusions: DX in combination with standard radiation appears to be well tolerated in patients with persistent PSA after RRP. [Table: see text] No significant financial relationships to disclose.
GROCCO'S SIGN.
Authors: J B Frankenheimer
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Influenza activity - United States and worldwide, 1999-2000 season, and composition of the 2000-01 influenza vaccine.
Authors: A. Hay, I. Gust, A. Hampson, K. Nerome, M. Tashiro, L. Canas, D. Lavanchay, R. Levandowski
Journal: MMWR Morbidity and Mortality Weekly Report (2000)