tbuckley/cabot-search huggingface dataset:
Abstract 1320: Reduced Fetuin-A Plasma Level is Associated with Faster Stenosis Progression and Increased Valvular Calcification in the Elderly Patients with Aortic Stenosis
Authors: Dania Mohty, Philippe Pibarot, Jean-Pierre Despres, Amelie Cartier, Benoit Arsenault, Patrick Mathieu
Journal: Circulation (2007)

Background: Fetuin A is a circulating calcium-regulatory glycoprotein that inhibits ectopic and vascular calcification. Aortic stenosis (AS) is a disease process involving an active calcification of the aortic valve (AV). Its prevalence increases markedly with aging. We examined the association between plasma level of Fetuin A and disease progression in AS Methods and Results: 114 patients operated for AS, were divided into 2 groups according to their age: the young and middle-age group included the first (25–65 y-o) and second (66–74 y-o) tertiles and the elderly group included the last tertile (range 75–88 y-o). Plasma Fetuin-A level was determined by Elisa method and calcium content of the AV by a chelator quantitative method respectively. The annualized progression rate of the disease was calculated for the subset of patients in whom at least 2 transthoracic echocardiography separated by at least 6 months were available pre-operatively. In the elderly group, the preoperative progression rate of the maximum transvalvular gradient was 2-fold faster in patients with decreased plasma Fetuin-A level &lt;0.36 ng/ml (median value) when compared to those with higher level of Fetuin-A (10±4 vs. 5±3 mmHg, p=0.01). Moreover, there was a significant correlation between calcium content of the AV explanted at the time of surgery and Fetuin-A plasma level (R=0.37, p&lt;0.01). After adjusting for age, gender, bicuspid AV, creatinine, Fetuin-A remained significantly associated with AV calcification (R 2 =0.26, p=0.02). There was no correlation between Fetuin-A level and AV calcium content or AS progression in the younger patients group (R=0.06, p=0.62 and R=0.05, p=0.76, respectively) Conclusion: In the elderly patients, decreased level of Fetuin-A may contribute to enhanced valvular calcification and accelerated stenosis progression
Notes from the Field: Death Following Ingestion of an Edible Marijuana Product ― Colorado, March 2014
Authors: Jessica B. Hancock-Allen, Lisa Barker, Michael VanDyke, Dawn B. Holmes
Journal: MMWR Morbidity and Mortality Weekly Report (2015)

In March 2014, the Colorado Department of Public Health and Environment (CDPHE) learned of the death of a man aged 19 years after consuming an edible marijuana product. CDPHE reviewed autopsy and police reports to assess factors associated with his death and to guide prevention efforts. The decedent's friend, aged 23 years, had purchased marijuana cookies and provided one to the decedent. A police report indicated that initially the decedent ate only a single piece of his cookie, as directed by the sales clerk. Approximately 30-60 minutes later, not feeling any effects, he consumed the remainder of the cookie. During the next 2 hours, he reportedly exhibited erratic speech and hostile behaviors. Approximately 3.5 hours after initial ingestion, and 2.5 hours after consuming the remainder of the cookie, he jumped off a fourth floor balcony and died from trauma. The autopsy, performed 29 hours after time of death, found marijuana intoxication as a chief contributing factor. Quantitative toxicologic analyses for drugs of abuse, synthetic cannabinoid, and cathinones ("bath salts") were performed on chest cavity blood by gas chromatography and mass spectrometry. The only confirmed findings were cannabinoids (7.2 ng/mL delta-9 tetrahydrocannabinol [THC] and 49 ng/mL delta-9 carboxy-THC, an inactive marijuana metabolite). The legal whole blood limit of delta-9 THC for driving a vehicle in Colorado is 5.0 ng/mL. This was the first reported death in Colorado linked to marijuana consumption without evidence of polysubstance use since the state approved recreational use of marijuana in 2012.
Endoscopic resection of an esophageal duplication cyst with spraying of anhydrous alcohol
Authors: Yi Mou, Dingke Wen, Qin Liu, Honglin Chen, Hang Yi, Wei Liu, Bing Hu
Journal: Endoscopy (2015)

A 56-year-old man presented with progressive dysphagia for 12 months, but reported no weight loss and no significant medical history. Gastroscopy revealed a bulge with normal overlying mucosa in the lower esophagus ([Fig. 1]). Endoscopic ultrasound (EUS) showed a 5-cm hypoechoic intraluminal cystic mass with clear margins originating from the muscularis propria ([Fig. 2]). A well-defined cystic mass without internal enhancement was observed on computed tomography (CT) ([Fig. 3]).
DNMT3a Mutations Define a Pre-Leukemic Stem Cell Reservoir In Human Acute Myeloid Leukemia
Authors: Liran I. Shlush, Sasan Zandi, Amanda Mitchell, Weihsu Claire Chen, McLeod Jessica, Monica Doedens, Medeiros Jessie, Marke Rene, McPherson J John, Thomas J Hudson, Brown Andrew, Trinh M Quang, Lincoln D Stein, James A. Kennedy, Mark D. Minden, Jean C.Y. Wang, John E Dick
Journal: Blood (2013)
Abstract 5606: Outcomes of Patients With Acute Coronary Syndromes and Chronic Renal Insufficiency: Prognostic Importance of Troponin Elevation and Role of Adjunctive Antithrombotic Therapy (Analysis From the Acuity Trial)
Authors: Subasit Acharji, Eugenia Nikolsky, Roxana Mehran, Alexandra J Lansky, George D Dangas, Frederick Feit, Steven Manoukian, Ajay J Kirtane, Adriano Caixeta, Vijaya Kesanakurthy, Gregg W Stone
Journal: Circulation (2009)

Objective: To assess the prognostic value of elevated troponin in patients with acute coronary syndromes (ACS) and baseline chronic renal insufficiency (CRI) and impact of different antithrombotic regimens on outcomes of these pts. Background : Elevated troponin levels are useful in establishing diagnosis and prognosis in patients with ACS. However the role of troponin elevation in patients with CRI has been disputed. Methods and Results: In the ACUITY trial, among a total of 13,819 patients with ACS, baseline CRI defined as creatinine clearance &lt;60mL/min was present in 2179 pts (15.7%) of whom 1291 pts (59.2%) had troponin elevation. Patients with vs. without elevated troponin had significantly higher rates of 30-day mortality (4.7% vs. 1.0%, p&lt;0.0001), MI (8.3% vs. 5.0%, P=0.003) and composite ischemia (13.6% vs. 7.9%, p&lt;0.0001). The same was true with respect to 1-year rates of mortality (10.7% vs. 6.8%, p=0.0005), MI (13.3% vs. 7.3%, P&lt;0.0001) and composite ischemia (25.2% vs. 20.6%, p=0.002). By multivariable analysis, troponin elevation in patients with baseline CRI was an independent predictor of mortality at 30 days (OR [95%CI] = 4.75 [2.34, 9.65], P&lt;0.0001) and at 1 year (odds ratio [95%CI] = 1.58 [1.12, 2.23], P=0.009) as well as of MI at 1 year (OR [95%CI] = 1.54 [1.05, 2.25], P=0.02). Outcomes in patients with elevated troponin stratified by antithrombotic regimen are presented in the Table . Conclusions: In patients with ACS and CRI, troponin elevation is a marker of worse 30-day and 1-year outcomes. In high-risk pts with CRI and troponin elevation, bivalirudin monotherapy compared to heparin plus GPI resulted in significantly reduced rates of major bleeding without significant increase in 30-day and 1-year rates of composite ischemia.
Abstract 2768: Open-Label, Multicentre, Pharmacokinetic Study of IV Sildenafil in the Treatment of Neonates With Persistent Pulmonary Hypertension of the Newborn (PPHN)
Authors: Robin H Steinhorn, John P Kinsella, Ghazwan Butrous, Maria Dilleen, Michael Oakes, David L Wessel
Journal: Circulation (2007)
Abstract 15935: The Hispanic Paradox of Cardiovascular Mortality: A Systematic Review and Meta-Analysis
Authors: Mery J Cortes-Bergoderi, Kashish Goel, Mohammad Hassan Murad, Thomas Allison, Virend K Somers, Francisco Lopez Jimenez
Journal: Circulation (2011)

Background: Hispanics, the largest and the fastest growing minority in the U.S, have a higher prevalence of several cardiovascular (CV) risk factors like obesity, type 2 diabetes mellitus and ather...
Abstract 252: Negative D-dimer Test for Acute Aortic Dissection
Authors: Yukio Satoh, Masaru Suzuki, Akiko Shiroshita-Takeshita, Tomonori Tamura, Tomohiro Kurihara, Hideyuki Shimizu, Shingo Hori
Journal: Circulation (2011)

OBJECTIVE: Recent studies have indicated the effectiveness of D-dimer values as a negative predictor to rule out a diagnosis of acute aortic dissection (AAD) in patients with chest pain. In contrast, there are several other studies suggesting D-dimer levels are not always elevated in dissecting patients in emergency settings. The aim of the present study is to identify the independent predictors relating to negative results of D-dimer testing for AAD. METHODS: Single center prospective observational study was performed for 5 years in an emergency department of a university hospital in Tokyo. Consecutive 49 patients with AAD (32 males, median age: 63 y/o) were enrolled in this study. Diagnosis of AAD was confirmed by enhanced computed tomography (CT) in all patients. Of those, 18 patients presented Stanford type A and 22 patients had thrombosed false lumen. Venous blood was drawn soon after patients' arrival (all performed within 24 hrs from symptom onset, median time: 50 min), and WBC, CRP, and D-dimer levels were obtained. Dissection lengths were measured using CT by another physician in a blinded fashion. Univariate anlyses were performed by t-test or chi-square test where appropriate, and a Logistic regression analysis was used as a multivariate analysis. RESULTS: Medain (IQR) of plasma D-dimer levels of a consecutive series of 49 patients were 7.8 (0.3 to 113.8) μg/ml. Of the 49 patients, 5 (10.2%) showed negative D-dimer test results (&lt; 0.5μg/ml). Although age, sex, Stanford types, false lumen conditions, WBC, and CRP levels in these 5 patients were similar to those in other 44 patients with positive results, dissection length was significantly shorter in 5 negative results patients (132±119 vs 314±147 mm in positive results patients, P=0.01). The Logistic regression analysis using a backward elimination model revealed age and dissection length were identified as independent predictors for a negative D-dimer test result (Odds ratio and [95% CI]: 0.89 [0.79 to 0.99], 0.98 [0.96 to 0.99], respectively). CONCLUSION: In the present patient registry, 10% of patients with acute aortic dissection in emergency settings showed negative D-dimer test results. The negative D-dimer results were related to younger age and shorter dissection length.
哪些药物应该在药店出售？ 标准明确——包括安全性、用药时机和机会成本
Authors: RobertRFenichel, 张静, 莫玮, 周宏灏
Journal: BMJ (2005)

在美国等许多国家，用于事后避孕的左炔诺孕酮是一种处方药，而其他30多个国家则把它作为非处方药使用。最近，由于美国食品与药物管理局(FDA)提请将其转为非处方药或“药店销售药物”(OTC药物)，而使左炔诺孕酮广受关注”。该申请虽然基本上得到了FDA所有科研人员和顾问委员会的支持，却遭到了否决。否决原因与妇女们能否正确理解和使用该药有关，。但是，此前已对该问题进行了充分讨论，
Abstract 334: Observer Performance With State-of-the-Art T2 Weighted Sequences -T2p-singleshot SSFP, TSESSFP(ACUTE), IR-TSE (TIRM) and BLADE- for the Detection of Acute Myocardial Injury
Authors: Nathan Mewton, Magalie Viallon, Peter Kellman, Alto Stemmer, Stanislas Rappachi, Xiaoming Bi, Sven Zuehlsdorff, Didier Revel, Pierre Croisille
Journal: Circulation (2009)

Purpose: To assess the diagnostic performance of different T2 weighted (T2w) imaging sequences for the detection of acute myocardial injury (AMI) by cardiac magnetic resonance (CMR). Materials and ...
Abstract 13217: Effect Modification of Airborne Particulate Matter on Subclinical Atherosclerosis by Risk Factor Burden: The Multi-Ethnic Study of Atherosclerosis (MESA)
Authors: Norrina B Allen, Martha Daviglus, Sara Adar, Gregory L Burke, Ana Diez-Roux, Daniel O'Leary, Trivellore Raghunathan, James H Stein, Joel Kaufman
Journal: Circulation (2011)

Background: Associations between airborne particulate matter and subclinical measures of atherosclerosis have been inconsistent. We hypothesized that cardiovascular risk factor burden may modify th...
Abstract 17809: The Cardiovascular Phenotype of D-Dimer: From the Dallas Heart Study
Authors: Justin L Grodin, Tiffany M Powell, Colby R Ayers, Anand Rohatgi, Amit Khera, Darren K McGuire, Mark H Drazner, James A de Lemos, Sandeep R Das
Journal: Circulation (2011)

Background. The D-dimer antigen is a circulating marker of fibrin degradation; increased levels have been associated with coronary artery disease, systolic heart failure and all-cause mortality in clinical cohorts. However, its associations with cardiovascular phenotypes in the general population have not been described. Methods. In the Dallas Heart Study, a multi-ethnic probability-based population sample of Dallas County residents ages 30-65, we assessed associations between plasma D-dimer antigen and mortality, cardiac and aortic MRI measures (n=2500), and coronary calcium by EBCT (n=2536). Multivariable linear and logistic regression methods using log transformed D-dimer levels as the exposure variable were used to assess associations, adjusted for age, diabetes, smoking, hypertension, cholesterol, fat mass, lean mass, sex, and race. Results. Mean age was 44; 56% women, 52% African American. Median circulating D-dimer antigen was 0.22 μg/ml, ranging 0.04 to 8.85 μg/ml. Increasing D-dimer levels independently predicted all-cause mortality with a similar estimate for CV mortality prediction, although the latter was not statistically significant (Table). Increasing D-dimer also independently associated with increasing LV end diastolic volume and mass, but not with aortic or coronary atherosclerosis (Table). Conclusion. In this large, ethnically diverse, population-based cohort with detailed cardiovascular phenotyping, increasing plasma levels of D-dimer were not associated with atherosclerosis, but were independently associated with higher LV mass, larger end diastolic volume, and all-cause mortality.
Abstract 3151: Inflammatory Markers and Risk of Coronary Heart Disease in Relation to the Apob/Apoa-i Ratio in Healthy Men and Women; The Epic-Norfolk Population Study
Authors: Jamal S Rana, Benoit J Arsenault, Erik S Stroes, Mélanie Côté, Jean-Pierre Després, John J Kastelein, Nicholas J Wareham, Matthijs Boekholdt, Kay-Tee Khaw
Journal: Circulation (2008)

Studies have shown that individuals with an elevated apoB/apoA-I ratio are at increased risk for CHD. Presence of higher levels of inflammatory markers is also associated with increased CHD risk. The respective contributions of the apoB/apoA-I ratio and inflammatory markers to CHD risk are unknown. The apoB/apoA-I ratio and the plasma concentrations of an extensive panel of inflammatory markers including CRP, adiponectin, fibrinogen, myeloperoxidase, secretory phospholipase A2 (sPLA2) as well as lipoprotein-associated phospholipase A2 (Lp-PLA2) activity were measured in a prospective case-control study of 844 cases and 1762 matched controls (1651 men and 955 women) aged between 45–79 years who participated to the EPIC-Norfolk prospective population study. In both sexes, compared to participants in bottom apoB/apoA-I ratio tertile, participants in the top tertile had the highest levels of CRP (4.4 [3.7–5.0] vs. 2.8 [2.4 –3.2] mg/dL, p&lt;0.001 in men and 4.1 [3.4 – 4.8] vs. 3.1 [2.6 –3.6] mg/dL, p=0.03 in women), fibrinogen (3.2 [3.1–3.2] vs. 2.9 [2.8 –2.9] g/L, p&lt;0.001 in men and 3.2 [3.1–3.2] vs. 3.0 [2.9 –3.1] g/L, p&lt;0.001 in women) and the highest Lp-PLA2 activity (60.7 [59.3– 62.1] vs. 47.3 [46.0 – 48.6] nmol/min/mL, p&lt;0.001 in men and 55.6 [53.8 –57.4] vs. 41.5 [40.2– 42.8] nmol/min/mL, p&lt;0.001 in women) and the lowest adiponectin levels (7.9 [7.6 – 8.3] vs. 10.2 [9.7–10.6] μg/mL, p&lt;0.001 in men and 11.3 [12.7–13.5] vs. 15.5 [14.6 –16.1] μg/mL, p&lt;0.001). Myeloperoxidase and sPLA2 levels did not differ in apoB/apoA-I ratio tertiles. Compared to men in the bottom apoB/apoA-I ratio tertile and only 0 or 1 inflammatory markers in the top tertile (bottom for adiponectin), men in the top apoB/apoA-I ratio tertile had odds ratio (OR) for future CHD of 1.7 [95%CI 1.1–2.5], whereas those with 4, 5 or 6 inflammatory markers in the top tertile had an OR of 2.1 [1.4 –3.1] for future CHD. Among women, these OR for future CHD were of 1.7 [1.05–2.9] and 2.2 [1.2–3.9]. Men and women with an elevated apoB/apoA-I ratio also exhibited increased levels of inflammatory markers. The presence of additional elevated levels of multiple inflammatory markers was associated with an elevated CHD risk independent of higher levels of apoB/apoA-I ratio.
Abstract 725: Value of Speckle Tracking Analysis in Non-invasive Diagnosis of Cardiac Allograft Vasculopathy in Heart Transplant Patients
Authors: Violeta Sanchez, Juan F Delgado, Ana Gonzalez, Juan Torres, Sagrario Fernandez, Federico Lombera, Alberto Forteza, Carlos Saenz de la Calzada
Journal: Circulation (2009)
Abstract 13688: Long Chain Fatty Acid Composition Modulated by Elovl6 Plays a Critical Role in Vascular Smooth Muscle Cell Proliferation and Neointimal Formation
Authors: Hiroki Matsui, Hiroaki Sunaga, Saki Anjo, Mas Rizky A Syamsunarno, Tatsuya Iso, Takashi Matsuzaka, Hitoshi Shimano, Tomoyuki Yokoyama, Masahiko Kurabayashi
Journal: Circulation (2014)

Introduction: Elovl6, the elongase of long chain fatty acids 6, is a rate-limiting enzyme catalyzing the elongation of saturated and monounsaturated fatty acids with 12, 14 and 16 carbons. Our recent study showed that Elovl6 is abundantly expressed in vascular smooth muscle cells (VSMC) and is dramatically induced in neointima in rat. Hypothesis: In this study, we tested the hypothesis that changes of fatty acid (FA) composition by Elovl6 affects the proliferation of VSMC and contributes to neointimal formation in vivo. Methods and Results: Abundant Elovl6 expression was observed in mice femoral artery at 2 weeks after wire-injury and in intimal thickening lesion of human coronary artery. Furthermore, Elovl6 mRNA expression in cultured human aortic SMC (HASMC) was significantly increased by platelet-derived growth factor-BB (2.4-fold, p&lt;0.05) or hypoxic stress (6.7-fold, p&lt;0.01) in a dose- or time-dependent manner. Furthermore, knockdown of Elovl6 expression in HASMC markedly suppressed cell proliferation (16%, relative to control, p&lt;0.01) and migration, concomitantly induced the expression of p21 and phospholyration of AMP-activated protein kinase (p-AMPK) and suppressed mTOR expression. Consistent with in vitro data, Elovl6 deficient (Elovl6 -/-) mice at 2 weeks after injury showed markedly suppressed neointimal formation compared with wild-type (WT) mice (intima/media ratio: WT, 1.4 ± 0.6; Elovl6 -/-, 0.5 ± 0.2; Ki67-positive cells: 0.2 fold relative to WT mice; N=6-7, p&lt;0.05). Of an importance, analysis of FA composition in SMC isolated from Elovl6 -/- mice showed that high levels of palmitic acid and low levels of oleic acid were detected as compared with that from WT mice. In accordance with these results, exogenous treatment of palmitic acid in SMC substantially suppressed cell proliferation (42%, relative to control, p&lt;0.01) and migration, induced p21 and p-AMPK expressions. Conversely, these effects were blunted by adenovirus-mediated Elovl6-overexpression or exogenous oleic acid treatment. Conclusions: Collectively, our study demonstrates that proliferation of VSMC is tightly regulated by FA composition modulated by Elvlo6, offering a novel therapeutic target for arterial proliferative disease in which VSMC plays a key role.
Immunogenetic Characterization of Primary Immune Thrombocytopenia (ITP) in Adults: Results of the Unit Study
Authors: Francesco Zaja, Elena Boggio, Davide Rossi, Casimiro L. Gigliotti, Eleonora Toffoletti, Giuseppe Cappellano, Orilieri Elisabetta, Simona Puglisi, Monia Lunghi, Nicola Vianelli, Silvia Cantoni, Alessia Tieghi, Eloise Beggiato, Gianluca Gaidano, Miriam Isola, Renato Fanin, Umberto Dianzani
Journal: Blood (2014)
Abstract 17017: High-Sensitivity Troponin T is Associated with Worse Diastolic Function and Greater LV Mass among Elderly Persons in the Community without Prevalent Cardiovascular Disease
Authors: Amil M Shah, Christie M Ballantyne, Dalane Kitzman, Kunihiro Matsushita, Suma Konety, Kenneth Butler, Scott D Solomon
Journal: Circulation (2014)

Introduction:  High-sensitivity troponin T (hsTn-T) is associated with LV hypertrophy, reduced ejection fraction (EF), and incident heart failure (HF). However, the majority of HF cases in the elderly have preserved EF and the relationship of hsTn-T with diastolic dysfunction is not known.   Hypothesis:  We hypothesized that higher hsTn-T is associated with worse diastolic function among elderly persons without prevalent cardiovascular disease (CVD).   Methods:  Same day echocardiography and hsTn-T were performed in 4,304 elderly participants in the Atherosclerosis Risk in Communities (ARIC) study who were free of prevalent CVD. LV structure (wall thickness, volumes, mass), systolic function (EF), and diastolic function (early diastolic relaxation velocity [e’], E wave/e’ ratio, left atrial volume index [LAVi]) were assessed in a core laboratory. Echocardiographic measures were compared across five gender-specific categories of hsTn-T in analyses adjusting for age, gender, race, field center, hypertension, diabetes, chronic kidney disease, smoking, body mass index, systolic blood pressure, and kidney function.   Results:  Mean age was 76±5 years, 62% were women, 79% white, 79% had hypertension, and 34% diabetes. Mean LVEF was 66±5%, with median hsTn-T 10 ng/L (IQR 7-14) . In multivariable models, higher hsTn-T category was associated with greater LV mass index due to both greater LV wall thickness and volume, and worse measures of LV diastolic function, including E’, the E/E’ ratio and LAVi (adjusted p value for all associations    Conclusions:  Among elderly persons without prevalent CVD, higher hsTn-T is independently associated with worse LV diastolic function in addition to greater LV structural remodeling.
Comment on stEP (Scholz J, Mannion RJ, Hord DE, Griffin RS, Rawal B et al(2009)) A Novel Tool for the Assessment of Pain: Validation in Low Back Pain
Authors: H. Timmerman, A.P. Wolff, H.C.A.M. van Rijswijk, K.C.P. Vissers
Journal: PLoS Medicine (2009)
Antihypertensive treatment and compliance
Authors: J.-J. Parienti, M. Burnier, H R Brunner, K. Schroeder, A. Montgomery, S. Ebrahim, E. Battegay, R. Nuesch, B. Martina, T. Dieterle
Journal: BMJ (2001)

EDITOR-Nuesch et al suggest that noncompliance with treatment may not be associated with resistance to antihypertensive treatment.1Although there is little evidence on this topic, Burnier et al came to the opposite conclusion in a recent publication.2 3 Their study included 41 hypertensive patients resistant to a regimen including three drugs.Electronic monitoring of compliance alone for two 11/6/2015
Abstract 1537: Right Bundle Branch Block Induced by Exercise: Rare but Ominous
Authors: Ricardo Stein, Joshua Abella, Patricia Nguyen, Harold Olson, Jonathan Myers, Victor Froelicher
Journal: Circulation (2009)

BACKGROUND: Exercise-induced right bundle branch block (EI-RBBB) is an uncommon event during exercise testing (ET). The prognostic significance of EI-RBBB has not been determined and consistent stu...
Abstract 647: Important Role of Positive Family History of Sudden Death in Risk Stratification and Prevention of Death with the Implantable Defibrillator in Patients with Hypertrophic Cardiomyopathy
Authors: J. M Bos, Barry J Maron, Michael J Ackerman, Tammy S Haas, Paul Sorajja, Rick A Nishimura, Bernard J Gersh, Steve R Ommen
Journal: Circulation (2008)

Background: Prophylactic implantation of a cardioverter defibrillator (ICD) is indicated in the presence of risk factors (RF) for sudden death (SD) in patients with hypertrophic cardiomyopathy (HCM...
Abstract 12161: Persistent Cardiac Troponin Elevation During Acute Heart Failure Syndrome and Catecholamine Use
Authors: Satoshi Koyama, Yukihito Sato, Hideaki Inazumi, Yohei Tanada, Hisayoshi Fujiwara, Yoshiki Takatsu
Journal: Circulation (2012)

Inotrope use and high cardiac troponin concentration are both known prognostic markers for patients with worsening acute heart failure syndrome. However, the relationship between these 2 parameters...