THE EFFECT OF PENICILLIN ON THE RENAL LESIONS OF SUBACUTE BACTERIAL ENDOCARDITIS
Authors: D M SPAIN, D W KING
Journal: Annals of Internal Medicine (1952)

Article1 April 1952THE EFFECT OF PENICILLIN ON THE RENAL LESIONS OF SUBACUTE BACTERIAL ENDOCARDITISDAVID M. SPAIN, DONALD W. KINGDAVID M. SPAIN, DONALD W. KINGAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-36-4-1086 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe use of antibiotics, in particular penicillin, in the treatment of subacute bacterial endocarditis has so altered the course of the disease that infection is arrested in all but 10 per cent of cases treated. Only about 10 to 20 per cent die from the complications of the disease itself. The exact rôle of the renal lesions as a cause of death in treated cases of subacute bacterial endocarditis is still not settled. A report by Christie1on 269 patients treated with penicillin listed 73 deaths of which 8 were due to uremia. However, in a study by Pillsbury and...Bibliography1. Christie RV: Penicillin in subacute bacterial endocarditis, Brit. M. J. 1: 1, 1948. CrossrefMedlineGoogle Scholar2. PillsburyFiese PLMJ: Subacute bacterial endocarditis (follow-up study of 30 patients treated with penicillin), Arch. Int. Med. 85: 1, 1950. CrossrefGoogle Scholar3. BaehrSchifrin GA: Rarity of glomerulonephritis in rheumatic fever and its significance, Libman Anniv. Vol. 1: 125, 1932. Google Scholar4. HartmanBland SAEF: Rheumatic fever and glomerulonephritis, Am. J. Med. 10: 47, 1951. CrossrefMedlineGoogle Scholar5. Ehrström MC: Beiträge zur Frage der allergischen Pathogenese der diffusen Glomerulonephritis, Acta med. Scandinav. 106: 182-201, 1941. CrossrefGoogle Scholar6. Sarre H: Die Bedeutung der experimentellen Forschung zur Pathogenese der menschlichen diffusen Glomerulonephritis, Deutsche med. Wchnschr. 65: 1661, 1939. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication October 15, 1951.From the Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, N. Y.†Department of Laboratories and Research of Westchester County, Valhalla, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEndocarditis-Associated GlomerulonephritisEndocarditisCase 20-2012Infective Endocarditis Developing as UremiaRenal pathological findings in infective endocarditisGlomerulonephritis in Bacterial EndocarditisSurgical treatment of endocarditisAcute Glomerulonephritis and Glomerulonephritis in Bacterial EndocarditisCrescentic involved glomerulonephritis in infective endocarditisImmunopathogenetic Aspects of Infective EndocarditisImmunosuppressive Therapy and Plasmapheresis in Rapidly Progressive Glomerulonephritis Associated With Bacterial EndocarditisGlomerulonephritis in bacterial endocarditisGlomerulonephritis in Bacterial EndocarditisNierenbeteiligung bei infektiöser EndokarditisRenal Complications of Infectious DiseasesMesangio-capillary glomerulonephritis associated with Q-fever endocarditisCase 49-1975Renal consequences of valvular heart diseasePathoanatomic, Pathophysiologic and Clinical Correlations in EndocarditisInfective endocarditis—1973PATHOLOGY OF RENAL INTERSTITIUM: -ESPECIALLY IN VARIOUS INFLAMMATORY DISEASES-Aortic Valvular Bacterial Endocarditis in Tetralogy of Fallot Following Blalock AnastomosisRenal Aspects of Cardiac DiseaseInfection as a cause and complication of renal diseaseTHE DEVELOPMENT OF THE NEPHROTIC SYNDROME DURING THE COURSE OF CONGESTIVE HEART FAILURE: CASE REPORT AND REVIEW OF THE LITERATURE*JOHN M. THAYER, M.D., F.A.C.P., WILLIAM J. GLECKLER, M.D., F.A.C.P., ROBERT O. HOLMES, M.D.Erkrankungen des EndokardDie Herz- und GefäßkrankheitenRenal Function in Health and DiseaseTreatment of Bacterial Endocarditis 1 April 1952Volume 36, Issue 4Page: 1086-1089KeywordsAntibioticsBacterial diseasesEndocarditisInfectious diseasesLesionsPenicillinResearch laboratoriesSurgeons ePublished: 1 December 2008 Issue Published: 1 April 1952 PDF downloadLoading ...