tbuckley/cabot-search huggingface dataset:
Functional Nerve Disease. An Epitome of War Experience for the Practitioner.
Authors: Hugh Crichton-Miller
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Kahn Test. A Practical Guide.
Authors: R. L. Kahn
Journal: Annals of Internal Medicine (1929)

"The purpose of this volume is to present a brief summary of the precipitation phenomenon in syphilis and a detailed discussion of the technical aspects of the Kahn test." It is to be regarded as an elaboration or a second edition of the section on procedure in "The Serum Diagnosis of Syphilis by Precipitation." The work is divided into nine chapters, the first dealing with the phenomenon of precipitation in syphilis with reference to the Kahn reaction, in which the author correlates the principles governing precipitation in syphilis with the general principles controlling precipitation in colloidal systems. The other eight chapters deal with the purely technical phases of the test and are clearly and concisely presented. Although intended primarily for laboratory workers, this book should prove of interest and value to the physician, who should have a firm basis for his clinical interpretation of the results of the test.
Cardiovascular metabolic imaging: physiologic and biochemical dynamics in vivo
Authors: James B. Bassingthwaighte, Jeanie B. McMillin-Wood, Truman R. Brown, Thomas F. Budinger, Joanne S. Ingwall, Michael J. Rovetto, Heinrich R. Schelbert, Zena McCallum
Journal: Circulation (1985)

Fifty-eight investigators from the fields of biochemistry, physiology, cardiology, nuclear medicine, and physics met to discuss the development of metabolic imaging techniques for application to cardiovascular and pulmonary studies in health and disease. The workshop was sponsored by the Division of Heart and Vascular Diseases, National Heart, Lung, and Blood Institute and was held on September 16 to 18 in Bethesda, Maryland, in facilities provided by the American College of Cardiology. This report summarizes the presentations and discussions and presents recommendations for future studies.
Abstract 1725: Long Pentraxin3 (PTX3) is More Specific than CRP as a Marker for Vascular Inflammation
Authors: Taro Shiga, Koji Maemura, Yasushi Imai, Daiji Kawanami, Norihiko Takeda, Jiro Ando, Toshihiro Morita, Ichiro ManabeDobun Hayashi, Akira Sugiyama, Kyoko Miyamoto, Mina Sagara, Yukio Ito, Tsutomu Yamazaki, Yasunobu Hirata, Tatsuhiko Kodama, Ryozo Nagai
Journal: Circulation (2007)
Abstract 14131: Dark Chocolate Enhances Artery Dilatation Via Nox2 Down-regulation in Patients With Peripheral Arterial Disease
Authors: Lorenzo Loffredo, Roberto Carnevale, Pasquale Pignatelli, Cristina Nocella, Simona Bartimoccia, Monica Brancorsini, Elisa Catasca, Ludovica Perri, Francesco Violi
Journal: Circulation (2013)
Analytical Review of Reports from Pasteur Institutes on the Results of Anti-Rabies Treatment.
Authors: A. G. McKendrick
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Practical Approach to Pulmonary Medicine
Authors: Ronald H. Goldstein, James J. O'Connell, Joel B. Karlinsky
Journal: Thorax (1998)

Chest imaging pulmonary function testing pulmonary procedures allergy asthma community acquired pneumonia lung cancer tuberculosis fungal infections sarcoidosis hypersensitivity lung disease pleural effusion pneumothorax emphysema chronic bronchitis and bronchiectasis cystic fibrosis pulmonary hypertension and pulmonary vascular disease pulmonary rehabilitation acute and chronic respiratory failure obstructive sleep apnea neuromuscular disorders of the chest non-infectious parenchymal pulmonary diseases congenital lung disease lung abscess and empyema drug induced pulmonary disease HIV related respiratory problems pulmonary manifestations of systemic diseases pulmonary vasculitides occupational lung disease pulmonary diseases in pregnancy smoking cessation sick building syndrome and specific building related diseases disability evaluation theophylline/glucocorticoids oxygen therapy home care of the respiratory patient.
High dose chemotherapy with autologous stem cell transplant (ASCT) for mantle cell lymphoma (MCL)
Authors: E. Segota, B. Pohlman, T. Jin, E. Kuczkowski, L. Rybicki, M. Kalaycio, R. Sobecks, S. Andresen, B. Bolwell
Journal: Journal of Clinical Oncology (2005)

6668 Background: MCL patients (pts) that receive conventional chemotherapy have a poor prognosis with a 3-year (yr) progression-free survival (PFS) and overall survival (OS) of approximately 20% and 50%, respectively. Patients that receive ASCT have a PFS and OS ranging from 12–100% and 23–100%, respectively. To further clarify these widely variable results, we reviewed the ASCT experience at the Cleveland Clinic. Methods: Between 1996 and 2004, 38 MCL pts (32 males, 6 females) with median age 59 (range 34–72) yrs received high dose busulfan, etoposide, and cyclophosphamide with ASCT. At the time of ASCT, 24 pts were in 1st complete remission (CR, n=10) or partial remission (PR, n=14); 8 pts were in 2nd CR/PR; and 5 pts were in 3rd CR/PR. Median time from diagnosis to ASCT was 8.6 months, and the median follow-up among surviving patients is 21 months. Results: Fifteen patients (39%) have relapsed and 9 (24%) have died. The cause of death was MCL (n=7), pulmonary toxicity (n=1), and laryngeal cancer (n=1). The projected 3-year PFS and OS are 53% and 76%, respectively. Pts transplanted in 1st vs. 2nd or 3rd CR/PR had a higher 3-year PFS (62% vs. 43%, p=0.36) and OS (94% vs. 64%, p=0.036). Prior to ASCT, 1st CR/PR pts received either CHOP ± rituximab (R) or “HyperCVAD” ± R. Between subsets of pts transplanted in 1st CR/PR, the 3-year PFS and OS are not significantly different. Conclusions: MCL pts transplanted in 1st CR/PR benefit the most, appear to have a better OS (than conventionally treated pts), and should be considered for ASCT at diagnosis. Among subgroups transplanted in 1st CR/PR, no significant differences in PFS or OS were identified. Whether “HyperCVAD” + R prior to ASCT offers any advantage compared to CHOP + R prior to ASCT is unclear. Given the toxicity and difficulty in administering “HyperCVAD” (especially in older pts), a randomized study is warranted. No significant financial relationships to disclose.
A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer
Authors: Anees B. Chagpar, Brigid K. Killelea, Theodore N. Tsangaris, Meghan Butler, Karen Stavris, Fangyong Li, Xiaopan Yao, Veerle Bossuyt, Malini Harigopal, Donald R. Lannin, Lajos Pusztai, Nina R. Horowitz
Journal: New England Journal of Medicine (2015)

Routine resection of cavity shave margins (additional tissue circumferentially around the cavity left by partial mastectomy) may reduce the rates of positive margins (margins positive for tumor) and reexcision among patients undergoing partial mastectomy for breast cancer.In this randomized, controlled trial, we assigned, in a 1:1 ratio, 235 patients with breast cancer of stage 0 to III who were undergoing partial mastectomy, with or without resection of selective margins, to have further cavity shave margins resected (shave group) or not to have further cavity shave margins resected (no-shave group). Randomization occurred intraoperatively after surgeons had completed standard partial mastectomy. Positive margins were defined as tumor touching the edge of the specimen that was removed in the case of invasive cancer and tumor that was within 1 mm of the edge of the specimen removed in the case of ductal carcinoma in situ. The rate of positive margins was the primary outcome measure; secondary outcome measures included cosmesis and the volume of tissue resected.The median age of the patients was 61 years (range, 33 to 94). On final pathological testing, 54 patients (23%) had invasive cancer, 45 (19%) had ductal carcinoma in situ, and 125 (53%) had both; 11 patients had no further disease. The median size of the tumor in the greatest diameter was 1.1 cm (range, 0 to 6.5) in patients with invasive carcinoma and 1.0 cm (range, 0 to 9.3) in patients with ductal carcinoma in situ. Groups were well matched at baseline with respect to demographic and clinicopathological characteristics. The rate of positive margins after partial mastectomy (before randomization) was similar in the shave group and the no-shave group (36% and 34%, respectively; P=0.69). After randomization, patients in the shave group had a significantly lower rate of positive margins than did those in the no-shave group (19% vs. 34%, P=0.01), as well as a lower rate of second surgery for margin clearance (10% vs. 21%, P=0.02). There was no significant difference in complications between the two groups.Cavity shaving halved the rates of positive margins and reexcision among patients with partial mastectomy. (Funded by the Yale Cancer Center; ClinicalTrials.gov number, NCT01452399.).
Sarcoidosis: Clinical Management.
Authors: Om P. Sharma
Journal: Annals of Internal Medicine (1985)

and the psychological impact of cancer chemo- therapy.A paper on the thalidomide child as an adult is followed by an autobiographical chapter by a thalidomide child/adult.Several excellent chapters on inflammatory bowel disease and coeliac disease are followed by a study of the hopes and fears of chronically sick teenagers with fibro- cystic disease.The cardiovascular chapters are authoritative and critical contributions by clini- cians and epidemiologists.This is a book to be read and enjoyed.
Long term results of pati ents with hairy cell leukemia treated with cladribine
Authors: D. C. Case, T. J. Ervin, M. A. Boyd, F. R. Aronson, J. A. Hedlund
Journal: Journal of Clinical Oncology (2005)

6701 Background: Hairy cell leukemia is a chronic B-cell lymphoproliferative disorder involving bone marrow and spleen. A high complete response rate utilizing cladribine with long durable responses and survival has been documented in a large series (G. Goodman, et al, J. Clin. Onc. 21:891–896, 2003). We have reviewed our long-term experience with hairy cell leukemia treated with cladribine. Methods: We reviewed the results of all patients who had received cladribine ≥5 years ago. From 1992–2000 13 patients received cladribine 0.1 mg/kg/d continuous I.V. infusion for 7 days. Each received one course and were re-evaluated. Patients in complete remission were followed without additional treatment. Patient Characteristics: There were 11 males and 2 females. The ages ranged from 37–76 years (median 54 years). Ten patients were previously untreated. Four patients had previously received interferon with two also receiving prior pentostatin. Responses and Survival: Complete responses characterized by normal blood counts and bone marrow examination were achieved in all 13 patients. Only one cycle of treatment was utilized in each patient. All patients have remained in remission from 4+ -12+ years (median 7+ years). Survival from diagnosis ranges from 4+ - 16+ years (median 9+ years). At 12 years after treatment, survival is projected at 76%. Three patients have expired from atherosclerotic heart disease at 7, 8, and 10 years (ages 78, 79, & 85 years). One patient has developed ovarian cancer at 8 years. One cycle of cladribine can produce long-term responses in patients with hairy cell leukemia. In this small series a pattern of relapses has not been defined. No significant financial relationships to disclose.
Abstract 9298: Factors Impacting Growth in Infants with Single Ventricle Physiology in the First Year of Life: The Pediatric Heart Network Infant Single Ventricle Trial
Authors: Richard V Williams, Victor Zak, Chitra Ravishankar, Karen Altmann, Jeffrey B Anderson, Andrew M Atz, Carolyn Dunbar-Masterson, Nancy S Ghanayem, Linda M Lambert, Karen J Lurito, Barbara Medoff-Cooper, Renee Margossian, Victoria L Pemberton, Jennifer Russell, Mario Stylianou, Daphne T Hsu
Journal: Circulation (2010)

Background: Growth failure is common in infants with single ventricle physiology (ISV). Factors influencing growth in the first year of life are not well understood. Objectives: To describe growth ...
Safety and Efficacy of Ruxolitinib in an Open-Label, Multicenter, Single-Arm, Expanded-Access Study in Patients with Myelofibrosis (MF): An 1144-Patient Update
Authors: Bruno Martino, Philipp le Coutre, Martin Griesshammer, Thomas Illmer, Rudolf Schlag, Cornelius F. Waller, Anna Marina Liberati, Philippe Schafhausen, Renato S Tavares, Alessandro M. Vannucchi, Pilar Giraldo, Lynda M Foltz, Pia Raanani, Vikas Gupta, Bayane Tannir, Julian Perez Ronco, Jaggannath Ghosh, Haifa Kathrin Al-Ali
Journal: Blood (2014)
Lay members can contribute much in primary care groups
Authors: R. Rowe
Journal: BMJ (2001)

EDITOR—Contrary to the findings of the King's Fund that lay members of primary care groups are finding it difficult to ensure that patients' views are heard, 1 2 a study of lay members conducted by the University of Bristol indicates that they are increasingly confident in their ability to influence decision making.

In a postal survey of all primary care groups in the South West …
Motivation as Related to Personality.
Authors: Dorothy Rethlingshafer
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 14038: In-Stent Restenosis (ISR) is Not Simply a Benign Clinical Entity as It Presents as an Acute Coronary Syndrome (ACS) in 40% of Cases
Authors: Adam Graham, Mohammed M Akhtar, Daniel Jones, Krishna Rathod, S Gallagher, Ajay Jain, Sam Mohiddin, Charles Knight, Anthony Mathur, Andrew Wragg
Journal: Circulation (2011)

Background: ISR following stent implantation may occur in 20% to 40% of cases according to patient and lesion complexity. Previously, ISR used to be seen as a “benign” event, but recent studies sug...
Abstract 1774: The Prognosis of a Normal Stress-Only SPECT Myocardial Perfusion Imaging Study
Authors: William L Duvall, Louai Razzouk, Nagib T Chalfoun, Milena J Henzlova
Journal: Circulation (2007)

Objectives: To determine the prognosis of stress-only SPECT MPI in routine clinical practice. Background: With normal stress perfusion images, rest imaging appears superfluous. Stress-only imaging ...
Abstract 12798: Mutation Site-Specific Differences in Arrhythmic Risk in the LQT3 Form of Congenital Long QT Syndrome: Multicenter Study in Japan
Authors: Takeshi Aiba, Hisaki Makimoto, Kenichiro Yamagata, Minoru Horie, Satoshi Ogawa, Yoshifusa Aizawa, Tohru Ohe, Kengo F Kusano, Masakazu Yamagishi, Naomasa Makita, Toshihiro Tanaka, Takeru Makiyama, Masao Yoshinaga, Nobuhisa Hagiwara, Naokata Sumitomo, Futoshi Toyoda, Hiroshi Matsuura, Shiro Kamakura, Yoshihiro Miyamoto, Wataru Shimizu
Journal: Circulation (2011)

Risk stratification in the patients with long QT syndrome type 3 (LQT3) is lacking. We hypothesized that mutations in the pore-forming segment between S5 through S6 (S5-S6) of the cardiac sodium ch...
Abstract 18274: Comparative Effectiveness of Stacked versus Single Shock Therapy for In-Hospital Cardiac Arrest: Insights from the Get With the Guidelines-Resuscitation Registry
Authors: Steven M Bradley, Wenhui Liu, Gary K Grunwald, Paul S Chan, Brahmajee K Nallamothu, Comilla Sasson, Paul D Varosy, Monique L Anderson, Preston M Schneider, P. Michael Ho
Journal: Circulation (2014)

Background: Among patients with cardiac arrest due to ventricular tachycardia or ventricular fibrillation (VT/VF), guidelines emphasize single shock protocols to minimize interruptions in chest compressions that may impair patient outcomes. The adoption and impact of single shock protocols on survival of in-hospital VT/VF arrest is unknown. Methods: In the Get With The Guidelines - Resuscitation multicenter observational registry, we identified 4,114 adults with in-hospital cardiac arrest due to VT/VF between 2004 and 2012, an immediate post-shock rhythm of VT/VF following the initial defibrillation attempt, and a second defibrillation attempt within 3 minutes of the first shock. The time interval in minutes from the initial shock to second shock was used to define stacked shock (time interval of 0 to 1 minute) and single shock protocols (time interval of 2 to 3 minutes). We first evaluated temporal trends in the use of stacked versus single shock protocols. We then used hierarchical regression adjusting for patient arrest characteristics and comorbidities while accounting for clustered observations by hospital to determine the association between stacked versus single shocks for VT/VF and survival to discharge. For this analysis, we restricted our cohort to the 2,984 (72.5%) patients with VT/VFarrest occurring at one of 150 hospitals with the use of both stacked and single shock approaches and at least 10 events during the study period. Results: The proportion of patients receiving a single shock protocol for VT/VF following an initial defibrillation attempt doubled from 25% in 2004 to more than 50% in 2012. Compared with patients treated with stacked shocks, treatment with single shocks was associated with a lower risk-adjusted survival to discharge (odds ratio 0.81, 95% confidence interval 0.68 to 0.98, P=0.03). Conclusion: Among adults with in-hospital VT/VFarrest, use of single shocks has increased since 2004 in accordance with guideline recommendations. However, compared with stacked shocks, single shocks for VT/VF was associated with decreased odds of survival to discharge. These observational findings suggest further investigation is needed to define the optimal defibrillation strategy for management of in-hospital VT/VF arrest.
A Study in Nutrition: An Inquiry into the Diet of 154 Families of St. Andrews.
Authors: E. P. Cathcart, A. M. T. Murray
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal