CORTISONE AND THE TREATMENT OF HEAT STROKE
Authors: W H WAUGH
Journal: Annals of Internal Medicine (1954)

Case Reports1 October 1954CORTISONE AND THE TREATMENT OF HEAT STROKEWILLIAM H. WAUGH, M.D.WILLIAM H. WAUGH, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-41-4-841 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe antipyretic and hypothermic effects of corticotropin and cortisone are well documented. Kass and Finland1 showed that the febrile response to injections of typhoid bacilli and influenza virus could be lessened by corticotropin. Douglas and Paton2 demonstrated that corticotropin reduced the temperature both in normal animals and in experimental pyrexia. Therapeutically, adrenocortical hormones have been used to alleviate the pyrexia and toxemia of pneumonia,3 typhoid fever,4, 5 Rocky Mountain spotted fever6 and generalized peritonitis.7Ingraham, Matson and McLaurin8suggested that corticotropin and cortisone might help prevent the hyperthermia of hypothalamic damage which sometimes results from surgery for craniopharyngiomas. They observed...Bibliography1. KassFinland EHM: Effect of ACTH on induced fever, New England J. Med. 243: 693, 1950. CrossrefMedlineGoogle Scholar2. DouglasPaton WWWD: Hypothermic and antipyretic effect of preparations of ACTH, Lancet 1: 342, 1952. CrossrefMedlineGoogle Scholar3. KassIngbarFinland EHSHM: Effects of adrenocorticotropic hormone in pneumonia: clinical, bacteriological, and serological studies, Ann. Int. Med. 33: 1081, 1950. LinkGoogle Scholar4. SmadelLeyDierchs JEHLFH: Treatment of typhoid fever. I. Combined therapy with cortisone and chloramphenicol, Ann. Int. Med. 34: 1, 1951. LinkGoogle Scholar5. WoodwardHallDias-RiveraHightowerMartinezParker TEHERJAERT: Treatment of typhoid fever. II. Control of clinical manifestations with cortisone, Ann. Int. Med. 34: 10, 1951. LinkGoogle Scholar6. WorkmanHightowerBorgesFurmanParker JBJAFJJERT: Cortisone as an adjunct to chloramphenicol in the treatment of Rocky Mountain spotted fever, New England J. Med. 246: 962, 1952. CrossrefMedlineGoogle Scholar7. BolingNewkirkBaxterPartridgeMargenKinsell LJPJSLW: Use of ACTH in management of generalized peritonitis: preliminary report, J. Clin. Endocrinol. and Metabolism 12: 184, 1952. CrossrefGoogle Scholar8. IngrahamMatsonMcLaurin FDDDRL: Cortisone and ACTH as an adjunct to the surgery of craniopharyngiomas, New England J. Med. 246: 568, 1952. CrossrefMedlineGoogle Scholar9. Christian HA: The principles and practice of medicine, 16th Ed., 1947, D. Appleton-Century Co., New York, p. 545 (19). Google Scholar10. Yater WM: Fundamentals of internal medicine, 2nd Ed., 1944, D. Appleton-Century Co., New York, p. 627. Google Scholar11. BarrMusser DPJH: Internal medicine, 4th Ed., 1945, Lea & Febiger, Philadelphia, p. 1231. Google Scholar12. DailyHarrison WMTR: A study of the mechanism and treatment of experimental heat pyrexia, Am. J. M. Sc. 215: 42, 1948. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Augusta, Georgia*Received for publication February 5, 1954.From the Department of Medicine, U. S. Air Force Hospital, Nagoya, Honshu, Japan.†Present address: Departments of Physiology and Pharmacology, Medical College of Georgia, Augusta, Georgia. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTod und Gesundheitsbeschädigung durch von außen kommende EinwirkungenHeat StrokeMalignant hyperthermia: Aetiology unknownHeat strokeHeat stroke in the agedSchädigungen des ZNS durch physikalische EinwirkungenThe renal, cardiovascular, hematologic and serum electrolyte abnormalities of heat strokeHeatstroke and jaundice 1 October 1954Volume 41, Issue 4Page: 841-843KeywordsAdrenocorticotropic hormoneFeversHospital medicineHyperthermiaPharmacologyPneumoniaStrokeSurgeryTemperatureTyphoid ePublished: 1 December 2008 Issue Published: 1 October 1954 PDF downloadLoading ...