NEW DRUGS OF VALUE IN THE TREATMENT OF EPILEPSY
Authors: F A GIBBS
Journal: Annals of Internal Medicine (1947)

Article1 October 1947NEW DRUGS OF VALUE IN THE TREATMENT OF EPILEPSYFREDERIC A. GIBBS, M.D.FREDERIC A. GIBBS, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-27-4-548 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA drug that is good for one type of epileptic seizure may be bad for another; for example, Dilantin is an excellent anticonvulsant, but in many cases it increases the number and severity of petit mal seizures, and Tridione, which is often dramatically effective against petit mal, may increase the number of grand mal. Thus, in order to proceed as rationally as possible with the treatment of an epileptic patient, the type or types of epileptic seizure should be classified. The major types of epileptic seizure and the drugs which are beneficial in their treatment are shown in table 1....Bibliography1. MERRITTPUTNAM HHTJ: Sodium diphenyl hydantoinate in the treatment of convulsive disorders, Jr. Am. Med. Assoc., 1938, cxi, 1068. CrossrefGoogle Scholar2. HAUPTMANN A: Luminal bei Epilepsie, Munchen. med. Wchnschr., 1912, ii, 1907. Google Scholar3. LOSCALZO AE: Treatment of epileptic patients with a combination of 3-methyl 5, 5 phenylethyl-hydantoin and phenobarbital, Jr. Nerv. and Ment. Dis., 1945, ci, 537. Google Scholar4. KOZOL HL: The treatment of epilepsy with methylphenylethyl hydantoin (Mesantoin), Proc. Assoc. Res. Nerv. and Ment. Dis., 1946. In press. Google Scholar5. LOCOCK C, in discussion on SIEVEKING, E. H.: Analysis of 52 cases of epilepsy observed by the author, Lancet, 1857, i, 528. Google Scholar6. PERLSTEINANDELMAN MAMB: Tridione—its use in convulsive and related disorders, Jr. Pediat. 1946, xxix, 20. CrossrefGoogle Scholar7. LENNOX WG: Petit mal epilepsies. Their treatment with Tridione, Jr. Am. Med. Assoc., 1945, cxxix, 1069. CrossrefGoogle Scholar8. MACKAYGOTTSTEIN RPWK: Aplastic anemia and agranulocytosis following Tridione, Jr. Am. Med. Assoc. 1946, cxxxii, 13-16. CrossrefGoogle Scholar9. HARRISONJOHNSONAYER FFRDD: Fatal aplastic anemia following use of Tridione and Hydantoin, Jr. Am. Med. Assoc., 1946, cxxxii, 11-13. CrossrefGoogle Scholar10. LENNOXDAVIS WGJP: Effects of trimethyloxazolidine dione (Tridione) and of dimethylethyloxazolidine dione on seizures and on the blood, Proc. Assoc. Res. Nerv. and Ment. Dis., 1946. In press. Google Scholar11. PETERMAN MG: The ketogenic diet, Jr. Am. Med. Assoc., 1928, xc, 1427. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Chicago, Illinois*Read before the General Assembly of the Illinois State Medical Society May 14, 1947. From the University of Illinois, College of Medicine, Department of Psychiatry, Chicago, Illinois. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byLymphadenopathy induced by anticonvulsant drugs and mimicking clinically and pathologically malignant lymphomasUse of the Dione Drugs (Propazone, Tridione, Paradione, Dimedione and Malidone) in the Treatment of Epilepsy of Children"MYSOLINE": A CLINICAL EVALUATION OF A NEW DRUG IN THE TREATMENT OF REFRACTORY CASES OF EPILEPSYDie cerebralen Anfallsleiden: Genuine Epilepsie, symptomatische Hirnkrämpfe und die NarkolepsieThe neuropharmacology of antiepileptics 1 October 1947Volume 27, Issue 4Page: 548-554KeywordsAnticonvulsantsDrugsEpilepsyEpileptic seizures ePublished: 1 December 2008 Issue Published: 1 October 1947 PDF downloadLoading ...