tbuckley/cabot-search huggingface dataset:
Recovery of cellular immunity following chemotherapy for AIDS related non Hodgkin’s lymphoma
Authors: M. Bower, J. Stebbing, M. H. Tuthill, J. Krell, V. Campbell, M. Nelson, B. Gazzard, T. Powles
Journal: Journal of Clinical Oncology (2008)

8582 Background: Late effects of chemotherapy on immunological parameters in AIDS-related systemic NHL have not been described. Methods: 105 consecutive patients were treated with infusional CDE chemotherapy and HAART and 68 survived more than 3 months following the chemotherapy. Their lymphocyte subsets and plasma HIV viral loads were measured at regular intervals for 2 years and values compared to baseline. Results: During chemotherapy, there were statistically significant falls in CD4 (helper T), CD8 (cytotoxic T) and CD19 (B) cell populations but no changes in the CD56 (natural killer) cell population. Amongst the 68 survivors, there were statistically significant increases in CD4, CD8, CD19 and CD56 populations during the first year of follow-up, compared to the values at the start of chemotherapy. The rises were most marked during the first 3 months of follow-up, and the median rise over the first year were +97 cells/mL for CD4, +318 cells/mL for CD8, +137 cells/mL for CD19 and +32 cells/mL for CD56. During the second year of follow-up further statistically significant rises were documented for CD4 and CD19 cell counts but not for CD8 or CD56 cell counts. Data are available for 43 patients at 2 years post chemotherapy and for these patients the median CD4 cell count rose from 165/mL (IQR: 62–252) at the start of chemotherapy to 270/mL (IQR: 174–445) 2 years after completing chemotherapy. At the start of chemotherapy only 27% patients had an undetectable HIV plasma viral load. This value rose to 69% at the completion of chemotherapy, to 79% at 3 months, 81% at 1 year and 90% at 2 years after completing chemotherapy. Much of the initial suppression of HIV viraemia is because 41% of the cohort were antiretroviral naïve and started HAART with their chemotherapy. During 244 years of follow-up following chemotherapy in these 68 survivors, 7 second primary tumours and 8 opportunistic infections were diagnosed. Conclusions: Chemotherapy and concomitant HAART for AIDS-related NHL does not cause prolonged suppression of lymphocyte subsets. These data should provide reassurance regarding the long term immunological consequences of chemotherapy in people with HIV. No significant financial relationships to disclose.
Abstract 13377: A Multicenter Study of 320 Slice CT in Chronic Atrial Fibrillation: A Comparison of Prospective and Retrospective ECG Gating
Authors: Hiroyuki Takaoka, Nobusada Funabashi, Masae Uehara, Koya Ozawa, Marehiko Ueda, Nanae Sato, Syunichi Kushida, Junji Kanda, Fukuko Nagura, Yoshihide Fujimoto, Yoshio Kobayashi
Journal: Circulation (2013)

Purpose: To compare diagnostic accuracy of prospective and retrospective ECG gating in 320 slice CT for detecting coronary stenosis in patients with chronic atrial fibrillation (CAF) in a multicent...
The Biochemistry of Clinical Medicine.
Authors: Ira Thabrew, Ruth M. Ayling, Claire Wicks
Journal: Annals of Internal Medicine (1964)

1. Cells and organelles 2. Carbohydrates 3. Carbohydrate metabolism and related disorders 4. Cellular energetics and energy production 5. Lipids 6. Lipid metabolism and related disorders 7. Proteins (+ proteins as functional units) 8. Metabolism of nitrogen containing compounds 9. Information storage and transmission 10. Information expression and proteins as functional units 11. Communication between cells and tissues in the body 12. Sodium, water and potassium 13. Hydrogen ion homeostasis 14. The cardiovascular system 15. Haemoglobin, porphyrias and iron 16. The liver 17. Gastrointestinal system 18. The kidney 19. Calcium, phosphate, magnesium and bone 20. The hypothalamic and pituitary glands 21. The thyroid gland 22. The adrenal glands 23. The gonads 24. Metabolic aspect of malignancy 25. Nutrition and nutritional disorders.
Complement Fixation in the Diagnosis of Amebiasis
Authors: Charles F. Craig
Journal: Annals of Internal Medicine (1931)

Article1 August 1931Complement Fixation in the Diagnosis of AmebiasisCHARLES F. CRAIG, M.A., M.D., F.A.C.P.CHARLES F. CRAIG, M.A., M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-5-2-170 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBy the term "amebiasis" is meant the condition brought about in the human body by the invasion of the tissues of the intestines byEndamoeba histolytica, the ameba causing that type of dysentery called "amebic dysentery". Most unfortunately, from the standpoint of a clear understanding of the importance of this parasite as a cause of disease in man, the term "amebic dysentery" has, until quite recently, been synonymous with "amebiasis" in the minds of the vast majority of the medical profession. In addition, the conception that infection withEndamoeba histolyticaoccurs only in the tropics and sub-tropics has led the...References1 DOCK G: Centralbl. f. Bakt., etc., 1891, x, 227. Google Scholar2 MUSGRAVE WE: Philippine Jr. Sci., 1910, v. 229. Google Scholar3 CRAIG CF: Jr. Am. Med. Assoc., 1921, lxxxviii, 19. Google Scholar4 LYNCH KM: Protozoan parasitism of the alimentary tract, 1930, p. 77, New York. Google Scholar5 CRAIG CF: Am. Jr. Trop. Med., 1927, vii, 225. CrossrefGoogle Scholar6 CRAIG CF: Am. Jr. Trop. Med., 1929, ix, 277. CrossrefGoogle Scholar7 CRAIG CF: Jr. Am. Med. Assoc., 1930, xcv, 10. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Medical Corps U. S. Army Washington, D.C.*From the Department of Preventive Medicine and Clinical Pathology, Army Medical School, Washington, D.C.†Read at the Baltimore Meeting of the American College of Physicians, March 25, 1931. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie Colitis UlcerosaAn Amebiasis Complement Fixation Test in the Diagnosis of Intestinal Amebiasis 1 August 1931Volume 5, Issue 2Page: 170-177KeywordsAmebiasisClinical pathologyDysenteryEntamoeba histolyticaPreventive medicine ePublished: 1 December 2008 Issue Published: 1 August 1931 PDF downloadLoading ...
The Evolution of Surgery in the United States.
Authors: Allen Oldfather Whipple
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Social Dimensions of AIDS: Method and Theory.
Authors: Douglas A. Feldman, Thomas M. Johnson
Journal: Annals of Internal Medicine (1986)

Part 1 Aids social research strategies: methodological issues in AIDS-related research, K.Siegel and L.Bauman applied methodology - a primer of pitfalls and opportunities in AIDS research, J.Zich and L.Temoshok. Part 2 Social epidemiology: behaviour, infection and immune response - an epidemiological approach, R.Flam and Z.Stein the case for a origin of the Aids epidemic, A.Moore and R.LeBaron the social origins of AIDS - social change, sexual behaviour and disease trends, W.Darrow et al. Part 3 Lifestyles and behavioural change: AIDS and needle sharing within the IV drug-use subculture D. Des Jarlais et al gay lifestyle change and AIDS - preventive health care, J.Kotarba and N.Lang AIDS health promotion and clinically applied anthropology, D. Feldman. Part 4 AIDS and the media: illness and deviance - the response of the press to AIDS, E.Albert the portrayal of AIDS in the media - an analysis of articles in the New York Times, A.Baker. Part 5 Health beliefs and behaviour: AIDS - a psychosocial perspective, V.Casper explanatory models for AIDS, D.Bolognone and T.Johnson fear of AIDS and its effects on the nation's blood supply, P.Callero et al. Part 6 Impact of AIDS on health-care delivery: hospice staff response to fear of AIDS, S.Geis and R.Fuller ideology and politics in the control of contagion - the social organization of AIDS care, R.Lessor and K.Jurich.
Authors differ on assessment of flaws in trials
Authors: I. F Burgess
Journal: BMJ (1995)

into question the concentration of efforts to prevent suicide on health care services.While supporting the need for good planning for patients' discharge, we believe that efforts should continue to identify other routes of intervention in the great majority of those dying by suicide, who have not been in contact with primary care or inpatient psychiatric services.Detailed examination of high risk groups, such as younger people and those in deprived communities,4 together with review of the scope for structural interventions, such as limiting the availability of popular methods of suicide,' may offer the greatest population benefits.
Post-Remission Treatment with Allogeneic Stem Cell Transplantation Improves Outcome in Patients Aged 60 Years and Older with Acute Myeloid Leukemia in First Remission
Authors: Jurjen Versluis, Carin L.E. Hazenberg, Wim van Putten, Jakob R Passweg, Johan Maertens, Bart J Biemond, Harry C Schouten, Thomas Pabst, Bob Lowenberg, Gert J Ossenkoppele, Edo Vellenga, Jan J Cornelissen
Journal: Blood (2014)
Clinical Preventive Dentistry. Based on a New Type of X-Ray Examination.
Authors: Howard Riley Raper
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Funeral Management and Costs. A World-Survey of Burial and Cremation.
Authors: Quincey Lamartine Dowd
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of Combined Local Treatment With Radioactive and Chemical Carcinogens
Authors: Arthur M. Cloudman, Katherine A. Hamilton, Ralph S. Clayton, Austin M. Brues
Journal: JNCI Journal of the National Cancer Institute (1955)

Effects of Combined Local Treatment With Radioactive and Chemical Carcinogens Get access Arthur M. Cloudman, Arthur M. Cloudman Division of Biological and Medical Research, Argonne National Laboratory, Lemont, Ill. Search for other works by this author on: Oxford Academic PubMed Google Scholar Katherine A. Hamilton, Katherine A. Hamilton Division of Biological and Medical Research, Argonne National Laboratory, Lemont, Ill. Search for other works by this author on: Oxford Academic PubMed Google Scholar Ralph S. Clayton, Ralph S. Clayton Division of Biological and Medical Research, Argonne National Laboratory, Lemont, Ill. Search for other works by this author on: Oxford Academic PubMed Google Scholar Austin M. Brues Austin M. Brues Division of Biological and Medical Research, Argonne National Laboratory, Lemont, Ill. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 15, Issue 4, February 1955, Pages 1077–1083, https://doi.org/10.1093/jnci/15.4.1077 Published: 01 February 1955 Article history Received: 05 November 1954 Published: 01 February 1955
Women's Health Research: A Medical and Policy Primer
Authors: Florence Haseltine, Lynne Beauregard, Beverly Jacobson
Journal: Annals of Internal Medicine (1997)

Foreword. Introduction and History. Women's health research: an introduction. Women's health research: a historical perspective. What We Know. How female and male biology differ. How one gender difference affects society. Diseases that only affect women. Diseases that are more prevalent in women. Diseases that manifest differently in women and men. Women's health and the environment. Women as Researchers and Participants. Formula for change: examining the glass ceiling. Funding for research and training. Needed: a women's health curriculum and program. The Political Agenda and Priorities. Including women in clinical trials: policy changes at the Food and Drug Administration. Scleroderma: a case study of policy. Women's health research: congressional action and legislative gains: 1990--1994. Conclusion. Index.
Epidural analgesia in labour
Authors: D. J Buggy
Journal: BMJ (1996)

Tuberculosis Research Unit for the streptomycin trial,4 which subsequently (from 1948) served as a model for randomisation in many later randomised controlled trials?Or is it because the results of the patulin trial were negative and those of the streptomycin trial made medical history?I have previously quoted Bradford Hill's re- collection that his statistical, and my medical, experiences in this field converged when we pre- pared for the streptomycin project.56The patulin trial certainly influenced my thinking.Yet, so far as I am aware, the literature on the modem clinical trial contains no recognition of this trial, despite its many deserving features.Should not this omission be rectified?
Cancer in Children. Clinical Management.
Authors: H. J. G. Bloom
Journal: Annals of Internal Medicine (1977)

General Chapters.- 1. Aetiology and Epidemiology.- 2. Pathology.- 3. Surgery (General Principles).- 4. Radiation Therapy.- 5. Cancer Chemotherapy.- 6. Infections in Children with Malignant Disease.- 7. General Care.- 8. Clinical Presentation and Diagnosis.- 9. Facilities for Paediatric Cancer Cases and Children's Tumour Registration.- Special Chapters.- 10. Tumours of the Central Nervous System.- 11. a) Retinoblastoma.- b) Other Tumours of the Eye and Orbit.- 12. Tumours of the Sympathetic Nervous System.- 13. Leukaemia.- 14. Malignant Lymphomas.- 15. Burkitt's Sarcoma.- 16. Histiocytosis.- 17. Bone Tumours.- 18. Soft Tissue Sarcomas.- 19. Teratomas in General and Tumours of the Reproductive Organs.- 20. Tumours of the Kidney.- 21. Skin Tumours.- 22. Liver Tumours.- 23. Tumours of Head and Neck.- 24. Miscellaneous Tumours.
Abstract 2732: Interacting Blood Pressure Loci in the Stroke-Prone Spontaneously Hypertensive Rat.
Authors: Delyth Graham, Martin W McBride, Kirsten Gilday, John D McClure, Anna F Dominiczak
Journal: Circulation (2007)

Background: In a previous genome wide linkage study we identified blood pressure quantitative trait loci (QTL) mapping to rat chromosome 2 and chromosome 3 in an F2 cross derived from SHRSP and WKY strains. We also identified a significant interaction between loci on chromosomes 2 and 3 using Pseudomarker (v 0.9) statistical framework. The aim of this study was to generate a double congenic strain to confirm chromosome 3 QTL and investigate the interaction between loci on the implicated chromosomes. Methods : A marker-assisted breeding strategy was used to generate the SP.WKYGla2a/3a double congenic strain (D2Rat13-D2Rat157, D3Mgh16-D3Wox28), using SHRSP as recipient and WKY as the donor strain. Haemodynamic measurements were carried out using radiotelemetry over a 5-week baseline period followed by 3 weeks of salt-loading (1%). Results : Radiotelemetry data for systolic blood pressure and pulse pressure are illustrated in figure a + b respectively. Systolic blood pressure was significantly reduced in the SP.WKYGa2a/3a strain (n=7) compared to SHRSP (n=13) (p = 0.0001, F = 97.77, repeated measures ANOVA). Pulse pressure was also significantly reduced compared to SHRSP (p=0.0001, F=34.17) and achieved levels comparable to WKY (n=10). Pulse pressure diurnal variation observed in SHRSP during salt-loading was abolished in the double congenic strain (AUC; p=0.0001, F=13.56). Conclusions : Almost complete reversal of SHRSP hypertensive haemodynamic profiles has been achieved in the SP.WKYGla2a/3a double congenic strain. This strain will allow interrogation of complex gene-gene, gene-environment interactions contributing to salt-sensitive hypertension in the SHRSP.
Nationwide outbreak of STEC O157 infection in the Netherlands, December 2008-January 2009: continuous risk of consuming raw beef products
Authors: K Greenland, C de Jager, A Heuvelink, K van der Zwaluw, M Heck, D Notermans, W van Pelt, I Friesema
Journal: Eurosurveillance (2009)

The Netherlands experienced a nationwide outbreak of Shiga toxin-producing Escherichia coli (STEC) O157 with onset of symptoms from the end of December 2008 until the end of January 2009. A total of 20 laboratory-confirmed cases were linked to the outbreak strain, serotype O157: H-, stx1, stx2, eae and e-hly positive. The investigation into the source of this outbreak is still ongoing, but evidence so far suggests that infection occurred as a result of consuming contaminated raw meat (steak tartare).
A Text-Book of the Diseases of Women.
Authors: John Clarence Webster
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Neurological Complications of Renal Disease
Authors: Charles Francis Bolton, G. Bryan Young
Journal: Annals of Internal Medicine (1990)

Historical introduction. Part 1: scientific background and critical approach uremic neurotoxins and the biochemical basis of neurological dysfunction in uremia approach to the nervous system in renal disease. Part 2: neurological effects of renal disease: uremic encephalopathy uremic neuropathology associated disorders of the nervous system. Part 3: neurological complications of treatment neurological complication of dialysis neurological complications of renal transplation the nervous system, drugs and uremia.
Abstract 14405: Plaque Volume of Carotid Endarterectomy (CEA) Specimens Measured Using a Novel 3-Dimensional Ultrasound (3DUS) Technology
Authors: Anirudh Kumar, Eric Y Yang, Gerd Brunner, Tyler O Murray, Zsolt Garami, John Volpi, Salim S Virani, Michael J Washburn, William Zang, Gerald M Lawrie, Rasadul Kabir, Christie M Ballantyne, Joel D Morrisett, Vijay Nambi
Journal: Circulation (2011)

Background: Accurate measurement of carotid plaque volume is an important measure for evaluating progression of carotid atherosclerosis. Using a novel GPS-like technique that allows for image fusio...