tbuckley/cabot-search huggingface dataset:
Deciphering the performance of macrophages in tumour microenvironment: a call for precision immunotherapy
Authors: Belén Toledo, Linrui Zhu Chen, María Paniagua-Sancho, Juan Antonio Marchal, Macarena Perán, Elisa Giovannetti
Journal: Journal of Hematology & Oncology (2024)

Abstract Macrophages infiltrating tumour tissues or residing in the microenvironment of solid tumours are known as tumour-associated macrophages (TAMs). These specialized immune cells play crucial roles in tumour growth, angiogenesis, immune regulation, metastasis, and chemoresistance. TAMs encompass various subpopulations, primarily classified into M1 and M2 subtypes based on their differentiation and activities. M1 macrophages, characterized by a pro-inflammatory phenotype, exert anti-tumoural effects, while M2 macrophages, with an anti-inflammatory phenotype, function as protumoural regulators. These highly versatile cells respond to stimuli from tumour cells and other constituents within the tumour microenvironment (TME), such as growth factors, cytokines, chemokines, and enzymes. These stimuli induce their polarization towards one phenotype or another, leading to complex interactions with TME components and influencing both pro-tumour and anti-tumour processes. This review comprehensively and deeply covers the literature on macrophages, their origin and function as well as the intricate interplay between macrophages and the TME, influencing the dual nature of TAMs in promoting both pro- and anti-tumour processes. Moreover, the review delves into the primary pathways implicated in macrophage polarization, examining the diverse stimuli that regulate this process. These stimuli play a crucial role in shaping the phenotype and functions of macrophages. In addition, the advantages and limitations of current macrophage based clinical interventions are reviewed, including enhancing TAM phagocytosis, inducing TAM exhaustion, inhibiting TAM recruitment, and polarizing TAMs towards an M1-like phenotype. In conclusion, while the treatment strategies targeting macrophages in precision medicine show promise, overcoming several obstacles is still necessary to achieve an accessible and efficient immunotherapy.
OS-043 Site-specific maturation dynamics of type 2 conventional dendritic cells connect with gamma delta T17 effector differentiation in cholestatic liver disease
Authors: Stefan Thomann, Ankit Agrawal, Helene Hemmer, Sagar Sagar, Paul Kießling, Emilia Scheidereit, Tanja Poth, Marcell Tóth, Katja Breitkopf-Heinlein, Nuh Rahbari, Christoph Kuppe, Dominic Grün
Journal: Journal of Hepatology (2024)
OS-039 A placebo controlled, randomized, double blinded trial to evaluate the use of Tolvaptan for correction of hyponatremia in liver cirrhosis patients
Authors: Zubair Mohamed, Arun Valsan, George Malayil, Anna Paul, S Sudhindran, Nipun Verma, G Unnikrishnan, Anoop Koshy, Dinesh Balakrishnan, Lakshmi Kumar, SaiBala Madathil
Journal: Journal of Hepatology (2024)
OS-070 Faecal microbiota transplantation in patients with cirrhosis, reduces antimicrobial resistance and enteric pathogen carriage, and enhances intestinal barrier function, associated with bacteriophage remodelling
Authors: Lindsey Edwards, Benjamin Auch, Theo Portlock, Benjamin H. Mullish, Blair Merrick, Charlotte Woodhouse, Thomas Tranah, Jesus Miguens Blanco, Lilianeleny Meoli, Anna Clavé Llavall, Victoria Kronsten, Ane Zamalloa, Vishal C. Patel, Julian R. Marchesi, Saeed Shoaie, Ivan Liachko, Simon Goldenberg, Debbie L. Shawcross
Journal: Journal of Hepatology (2024)
OS-045 The combination of TCR-redirected CD4+ and CD8+ T cells in T cell therapy of HBV infection enhances virus control in vivo by increasing IFN-γ and TNF-α secretion
Authors: Sophia Schreiber, Sven Schreiner, Eva Loffredo-Verde, Anna D. Kosinska, Ulrike Protzer
Journal: Journal of Hepatology (2024)
OS-081 Portal vein recanalization in non-cirrhotic patients with portal vein occlusion: first results of a VALDIG study
Authors: Pierre Deltenre, Killian Troch, Laure Elkrief, Anna Baiges, Fanny Turon, Aurélie Plessier, Michael Praktiknjo, Astrid Marot, Florent Artru, Veronika Fraitzl, Juan Carlos García-Pagán, Pol Olivas, Marco Dioguardi Burgio, Marta Barrufet, Marta Burell, Maria Ángeles García-Criado, Alexandre Soler, Louis Dalteroche, Carsten Meyer, Alban Denys
Journal: Journal of Hepatology (2024)
OS-018 Liver stiffness measurement by vibration-controlled transient elastography predicts adverse clinical outcomes in autoimmune hepatitis: results from a large multicenter longitudinal study
Authors: Ellina Lytvyak, Narmeen Umar, Gideon M. Hirschfield, Christina Plagiannakos, Hin HIn Ko, Mark G Swain, Julian Hercun, Lawrence Worobetz, Catherine Vincent, Jennifer Flemming, Karim Qumosani, Tianyan Chen, Dusanka Grbic, Angela Cheung, Devika Shreekumar, Iffat Iqbal, Madeline Cameron, Aliya Gulamhusein, Andrew L. Mason, Bettina Hansen, Aldo J Montano-Loza
Journal: Journal of Hepatology (2024)
OS-101-YI Remodelling of hepatocyte cholesterol metabolism mediates colorectal liver metastasis
Authors: Ane Nieva-Zuluaga, Beatriz Arteta, Mikel Ruiz de Gauna, Maider Apodaka-Biguri, Idoia Fernández-Puertas, Francisco González-Romero, Paul Gomez-Jauregui, Natalia Sainz-Ramírez, Kendall Alfaro-Jiménez, Beatriz Gómez Santos, Igotz Delgado, Andres Valdivieso, Javier Bustamante, Luis Bujanda, Jesus Maria Banales, Anastasios Giannou, Samuel Huber, Igor Aurrekoetxea, Xabier Buque, Patricia Aspichueta
Journal: Journal of Hepatology (2024)
OS-024 The gender-equity model for liver allocation built on artificial intelligence (GEMA-AI) improves outcome predictions among liver transplant candidates
Authors: Manuel Rodríguez-Perálvarez, Antonio M. Gómez-Orellana, David Guijo-Rubio, Pedro Gutierrez, Avik Majumdar, Geoff McCaughan, Rhiannon Taylor, César Hervás, Emmanuel Tsochatzis
Journal: Journal of Hepatology (2024)
OS-026-YI Functional role of CD44+ cancer stem cells in intrahepatic cholangiocarcinoma
Authors: Paula Cantallops Vilà, Laura Sererols Viñas, Gemma Garcia Vicién, Silvia Ariño, Carmen Cárcamo Giráldez, Laura Zanatto, Raquel A Martínez-García de la Torre, Li Chen, Giancarlo Castellano, Miguel Torres Martin, Robert F. Schwabe, Daniela Sia, Pau Sancho-Bru, Silvia Affo
Journal: Journal of Hepatology (2024)
OS-027-YI Immune checkpoint profiles on circulating extracellular vesicles predict response to immunotherapy in heptaocellular carcinoma
Authors: Ramsha Masood, Gustav Buescher, Joao Gorgulho, Franziska Giehren, Francesca Pagani, Lorenz Kocheise, Vincent Jörg, Constantin Schmidt, Lorenz Adlung, Moritz Waldmann, Thomas Renne, Jenny Krause, Guido Sauter, Franz Ricklefs, Cecile Maire, Mohsin Shafiq, Ansgar W. Lohse, Samuel Huber, Henning Wege, Carolin Zimpel, Jens U. Marquardt, Bernhard Scheiner, Lorenz Balcar, Matthias Pinter, Enrico de Toni, Ignazio Piseddu, Najib Ben Khaled, Kornelius Schulze, Johann von Felden
Journal: Journal of Hepatology (2024)
OS-028 Tumour, immune and parenchymal cell neighbourhoods correlate with survival after cholangiocarcinoma resection
Authors: Johannes Eschrich, Zuzanna Kobus, Hilmar Berger, Yeni Ait Ahmed, Natalja Amiridze, Marlene Kohlhepp, Christian Müller, Maria Reich, Niklas Heucke, Verena Keitel-Anselmino, Frank Tacke, Adrien Guillot
Journal: Journal of Hepatology (2024)
OS-040-YI Claudin-1 is a mediator and therapeutic target of biliary fibrosis by modulating liver progenitor cell fate and signaling
Authors: Fabio Del Zompo, Emilie Crouchet, Tessa Ostyn, Frank Jühling, Julien Moehlin, Natascha Roehlen, Tallulah Andrews, Diana Nakib, Catia Perciani, Sai Chung, Gary L. Bader, Ian Mcgilvray, Sonya MacParland, Roberto Iacone, Geoffrey Teixeira, Mathias Heikenwälder, Olivier Govaere, Tania Roskams, Catherine Schuster, Laurent Mailly, Thomas Baumert
Journal: Journal of Hepatology (2024)
OS-048 CD4+T cells license Kupffer cells to revert the CD8+T cell dysfunction induced by hepatocellular priming
Authors: Valentina Venzin, Cristian Beccaria, Valeria Fumagalli, Federica Moalli, Chiara Laura, Pietro Delfino, Leonardo Giustini, Elisa Bono, Chiara Perucchini, Marta Grillo, Keigo Kawashima, Pietro Di Lucia, Anna Celant, Sara De Palma, Giorgia De Simone, Elena Rodriguez Bovolenta, Luca Guidotti, Matteo Iannacone
Journal: Journal of Hepatology (2024)
OS-114 Liver transplantation following hepatocellular carcinoma downstaging with atezolizumab/bevacizumab: preliminary results of the prospective ImmunoXXL study
Authors: Sherrie Bhoori, Marianna Maspero, Michele Droz Dit Busset, Marco Bongini, Matteo Virdis, Davide Citterio, Carlo Sposito, Valentina Bellia, Carlo Battiston, Jorgelina Coppa, Maria Flores, Vincenzo Mazzaferro
Journal: Journal of Hepatology (2024)
OS-022 Kinetics of immunedysfunction in liver transplanted patients and impact on clinical outcome
Authors: Marie Charlotte Delignette, Arnaud Riff, Céline Guichon, Kayvan Mohkam, Alice Blet, Solène Pantel, Jérôme Dumortier, Tanguy Soustre, Francois Villeret, Fabien Zoulim, Fabienne Venet, Jean-Yves Mabrut, Teresa Antonini, Guillaume Monneret, Fanny Lebossé
Journal: Journal of Hepatology (2024)
GS-008 The combination of therapeutic vaccination with siRNA-mediated silencing of HBV and PD-L1 effectively breaks HBV-specific immunotolerance in high-titer HBV carrier mice
Authors: Anna D. Kosinska, Edanur Ates-Öz, Till Bunse, Merve Gültan, Swati Singh, Ulrike Protzer
Journal: Journal of Hepatology (2024)
OS-005-YI Single-cell RNA sequencing analysis in alcohol-related liver disease identifies specific cell subpopulations characterized by an inflammatory profile in alcohol-associated hepatitis
Authors: Jordi Gratacós-Ginès, Alex Guillamon-Thiery, Aina Rill, Alicia Martínez, Silvia Ariño, Ana Belén Rubio, Martina Perez-Guasch, Celia Martinez-Sanchez, Emma Avitabile, Anna Soria, Adrià Juanola, Isabel Graupera, Mar Coll, Ramon Bataller, Elisabetta Mereu, Pere Ginès, Elisa Pose
Journal: Journal of Hepatology (2024)
OS-020 MRI-serum based score accurately identifies liver transplant patients without rejection avoiding need for liver biopsy: a multisite european study
Authors: Jelte Schaapman, Elizabeth Shumbayawonda, Miguel Castelo-Branco, Filipe Caseiro Alves, Tania Costa, Emer Fitzpatrick, Katie Tupper, Anil Dhawan, Maesha Deheragoda, Eva Sticova, Marika French, Cayden Beyer, Soubera Rymell, Dimitar Tonev, Hein W Verspaget, Stefan Neubauer, Rajarshi Banerjee, Hildo Lamb, Minneke Coenraad
Journal: Journal of Hepatology (2024)
OS-080 Performance of spleen stiffness measurement by vibration-controlled transient elastography to rule out high-risk varices in patients with chronic extrahepatic portal vein obstruction without cirrhosis
Authors: Lucile Moga, Audrey Payancé, Luis Téllez, Lucia Giuli, Asunción Ojeda, Dario Saltini, Elton Dajti, Ekaterina Lusina, Dominik Bettinger, Francisco Capinha, Teresa Monllor-Nunell, Joel Silva, Magdalena Meszaros, Markus Peck-Radosavljevic, Sara Noemi Reinartz Groba, Christiane Stern, Laurent Castera, Michael Praktiknjo, Boris Guiu, José Alberto Ferrusquía, Carlos Noronha Ferreira, Maria Nadinskaya, Federico Ravaioli, Filippo Schepis, Fanny Turon, Francesco Santopaolo, Agustín Albillos, Pierre-Emmanuel Rautou, Aurélie Plessier
Journal: Journal of Hepatology (2024)
OS-065 Cerebral oedema at autopsy in acute liver failure: relationship to clinical features and changes over time
Authors: William Bernal, Mark JWMcPhail, Pervez Ali Khan, Stacey Calvert, Robert Loveridge, Christopher Willars, Tasneem Pirani, Sameer Patel, Georg Auzinger, Julia Wendon
Journal: Journal of Hepatology (2024)
OS-029 Claudin-1 is a driver for cholangiocarcinoma by modulating cancer cell plasticity and fate
Authors: Zeina Nehme, Marion Muller, Emilie Crouchet, Frank Jühling, Julien Moehlin, Romain Desert, Fabio Del Zompo, Jade Brochon-Toiser, Natascha Roehlen, Christine Thumann, Patrick Pessaux, Emanuele Felli, Aïna Venkatasamy, Mihaela Onea, Roberto Iacone, Markus Meyer, Alberto Toso, Nabeel Bardeesy, Lipika Goyal, Vikas Ranvir, Mirian Fernández-Vaquero, Mathias Heikenwälder, Tessa Ostyn, Tania Roskams, Patrice Laquerriere, Catherine Schuster, Laurent Mailly, Thomas Baumert
Journal: Journal of Hepatology (2024)
LBO-002 Efruxifermin significantly reduced liver fibrosis in MASH patients with F2-F3 fibrosis, with sustained improvement in liver injury and resolution of steatohepatitis over 96 weeks (HARMONY phase 2b study)
Authors: Stephen A. Harrison, Juan P Frias, Guy Neff, Gary Abrams, Kathryn Jean Lucas, William Sanchez, Sudhanshu Gogia, Muhammad Y Sheikh, Cynthia Behling, Pierre Bedossa, Lan Shao, Doreen Chan, Erica Fong, Brittany de Temple, Matthew Minerva, Kimberly Barrett, Reshma Shringarpure, Erik Tillman, Tim Rolph, Andrew Cheng, Vlad Ratziu, Kitty Yale
Journal: Journal of Hepatology (2024)
OS-025-YI Spatial single-cell profiling and network analysis reveal the immune architecture of hepatocellular carcinoma associated with immune checkpoint inhibitor therapy outcome
Authors: Henrike Salié, Lara Wischer, Ira Godbole, Patricia Otto-Mora, Juergen Beck, Antonio D'Alessio, Olaf Neumann, Albrecht Stenzinger, Andreas Blaumeiser, Melanie Boerries, Maike Hofmann, Robert Thimme, David J. Pinato, Thomas Longerich, Bertram Bengsch
Journal: Journal of Hepatology (2024)
GS-007 Prospective validation of the prognostic value of liver stiffness assessed by Fibroscan in primary sclerosing cholangitis: final results of the FICUS study
Authors: Olivier Chazouillères, Christoph Schramm, Palak J. Trivedi, Jonathan Bellet, Aymeric Monegier du Sorbier, Douglas Thorburn, Martti Färkkilä, Annarosa Floreani, Albert Pares, Cynthia Levy, Ulrich Beuers, Henriette Ytting, Ehud Zigmond, Bertus Eksteen, Pietro Invernizzi, Sara Lemoinne, Ansgar W. Lohse, Gideon M. Hirschfield, Nora Cazzagon, Llaura Llovet, Cyriel Ponsioen, Marco Carbone, Füssel Katja, Francesco Pezzato, Isha Patel, Jeltje Helder, Sheeba Khan, Karima Ben Belkacem, Gaouar Farid, Chantal Housset, Fabrice Carrat, Christophe Corpechot
Journal: Journal of Hepatology (2024)
WED-080 Hepatic inflammation-senescence-regeneration gene expression during recovery from ACLF and the effect of granulocyte-colony stimulating factor (GCSF), toll-like receptor-4 (TAK-242) inhibition and their combination (G-TAK)
Authors: MohammadMahdi Saeidinejad, Daniel Shaw, Cornelius Engelmann, Abeba Habtesion, Fausto Andreola, Rajiv Jalan
Journal: Journal of Hepatology (2024)
WED-123 Female mice with cirrhosis are more prone to acute and chronic effects of psilocybin exposure without tolerance compared to male mice
Authors: Jessica Maltman, Derrick Zhao, Alaina Jaster, Yunling Tai, Jing Zeng, Javier Maeso-Gonzalez, Huiping Zhou, Jasmohan Bajaj
Journal: Journal of Hepatology (2024)
OS-115 Results from a phase 2a randomized trial with the transglutaminase 2 inhibitor ZED1227 in patients with MASLD
Authors: Jörn M Schattenberg, Piotr Rozpondek, Krystyna Opawska, Sophie Metivier, Veronique Loustaud-Ratti, Luis Ibañez-Samaniego, Pere Ginès, Tobias Böttler, Elzbieta Blach, Diana Leeming, Morten Karsdal, Markus Proels, Judith Czarnecki, Michael Stiess, Ralph Müller, Manuel Romero-Gómez
Journal: Journal of Hepatology (2024)
WED-057 Exercise alters immune cell senescence and inflammation in cirrhosis patients with sarcopenia
Authors: Preeti Negi, Nidhi Nautiyal, Swati Thangariyal, Ashmit Mittal, Rakesh Kumar, Akhil Deshmukh, Vinod Arora, Shiv Kumar Sarin, Sukriti Baweja
Journal: Journal of Hepatology (2024)
TOP-072 Red blood cell distribution width-to-platelet ratio estimates the 3-year risk of decompensation in patients with metabolic dysfunction-associated steatotic liver disease-related cirrhosis
Authors: Mario Romeo, Marcello Dallio, Marina Cipullo, Paolo Vaia, Simone Mammone, Salvatore Auletta, Silvio Naviglio, Luigi Sapio, Angela Ragone, Marco Niosi, Alessandro Federico
Journal: Journal of Hepatology (2024)
THU-052 Therapeutic plasma-exchange improves short-term survival in patients with ACLF admitted to intensive care unit with organ failures-a multinational AARC data analysis
Authors: Rakhi Maiwall, Samba Siva Rao Pasupuleti, Ashok Kumar Choudhury, Vinod Arora, Mohd. Rela, Dinesh Jothimani, Mamun Al-Mahtab, Harshad Devarbhavi, CE Eapen, Ashish Goel, Cesar Yaghi, Qin Ning, Tao Chen, Jidong Jia, Zhongping Duan, Saeed Sadiq Hamid, Amna Subhan, Wasim Jafri, Akash Shukla, Soek-Siam Tan, Dong Joon Kim, Anoop Saraya, Jinhua Hu, Ajit Sood, Omesh Goyal, Vandana Midha, Manoj Sahoo, Guan-Huei Lee, Sombat Treeprasertsuk, Kessarin Thanapirom, Ameet Mandot, Samir Shah, Laurentius A. Lesmana, Hasmik Ghazinyan, Mohan Prasad V G, A. Kadir Dokmeci, Jose Sollano, Zaigham Abbas, Ananta Shrestha, George Lau, Diana Payawal, Gamal Shiha, Ajay Kumar Duseja, Sunil Taneja, Nipun Verma, Nagaraja Rao Padaki, Anand Kulkarni, Mithun Sharma, Md. Fazal Karim, Radha Krishan Dhiman, Ajay Mishra, Shahinul Alam, Osamu Yokosuka, Debashis Chowdhury, Chandan Kedarisetty, Sanjiv Saigal, Anil Arora, Ashish Kumar, Abraham Koshy, Ajay Kumar, Mohammed Elbasiony, Pravin Rathi, Sudhir Maharshi, V.M. Dayal, Ashish Kumar Jha, Kemal Fariz Kalista, Rino Gani, Man-Fung Yuen, Virendra Singh, Ayaskant Singh, Sargsyan Violeta, Chien-Hao Huang, Saurabh Mukewar, Shaojie Xin, Ruveena Bhavani, Charles Panackel, Sunil Dadhich, Sanjeev Sachdeva, Ajay Kumar, Sanatan Behera, Prabir Maji, Lubna Kamani, Hemamala Venugopal Saithanyamurthi, Dr. Joy Varghese, Pathik Parikh, P Javed, Neeraj Saraf, Narendra S. Choudhary, Akash Roy, Mahesh Goenka, Chetan Kalal, Krishnadas Devadas, Janaka De Silva H, Shiv Kumar Sarin
Journal: Journal of Hepatology (2024)
WED-100-YI Role of apoptosis in B-cell compartment retraction during decompensation of cirrhosis and acute-on-chronic liver failure
Authors: Lorena Paule, Javier Martínez González, Elisa Castillo, Alejandro Miranda, Leticia Munoz, Luis Téllez, Jorge Monserrat, Melchor Alvarez-Mon, Agustin Albillos
Journal: Journal of Hepatology (2024)
WED-125 Differential regulation of soluble guanylate cyclase signaling during liver fibrosis regression
Authors: Thomas Sorz-Nechay, Ksenia Brusilovskaya, Philipp Königshofer, Benedikt Hofer, Oleksandr Petrenko, Benedikt Simbrunner, Vlad Taru, Kerstin Zinober, Katharina Regnat, Katharina Bonitz, Henriette Horstmeier, Ines Truebenbach, Peng Sun, Stefan Günther Kauschke, Larissa Pfisterer, Michael Trauner, Philipp Schwabl, Thomas Reiberger
Journal: Journal of Hepatology (2024)
FRI-107-YI Folic acid prescription is associated with a lower mortality and hospital readmission in patients with decompensated alcohol-related liver cirrhosis
Authors: Laura Buttler, Anja Tiede, Marie Griemsmann, Hannah Schneider, Jim Benjamin Mauz, Heiner Wedemeyer, Markus Cornberg, Tammo Lambert Tergast, Benjamin Maasoumy, Katharina Luise Hupa-Breier
Journal: Journal of Hepatology (2024)
LBP-016 Carvedilol versus propranolol in the prevention of decompensation and mortality in patients with compensated and decompensated cirrhosis
Authors: Jose Fortea, Edilmar Alvarado-Tapias, Benedikt Simbrunner, Iranzu Ezcurra, Virginia Hernández-Gea, Carlos Ferre Aracil, Elba Llop Herrera, Angela Puente, Cristina Roig, Thomas Reiberger, Juan Carlos García-Pagán, Jose Luis Calleja Panero, Mattias Mandorfer, Càndid Villanueva, Javier Crespo
Journal: Journal of Hepatology (2024)
FRI-332 Mechanical stress of acute portal hypertension aggravates PAHSOS by damaging gut-vascular barrier targeting NR4A3/PV1
Authors: Han Zhang, Si Zhao, Rui Fang, Xue Wang, Suzhen Yang, Bing Xu, Ming Zhang, Yuzheng Zhuge, Jiangqiang Xiao
Journal: Journal of Hepatology (2024)
FRI-092 Thyroid and adrenal dysfunction is associated with negative midterm prognosis in decompensated cirrhosis
Authors: Laura Iliescu, Mircea Istrate, Razvan Rababoc, Simu Razvan-Ioan, Ioana Tanasie, Alexandra Alina Mihaela Mihaila, Letitia Toma
Journal: Journal of Hepatology (2024)
FRI-075 The lower, the worse? Impact of PHES results on the risk of overt hepatic encephalopathy in patients with minimal hepatic encephalopathy
Authors: Simon Johannes Gairing, Chiara Mangini, Lisa Zarantonello, Elise Jonasson Nielsen, Sven Danneberg, Philippe Sultanik, Peter R. Galle, Stefania Gioia, Joachim Labenz, Anna Lok, Jens U. Marquardt, Mette Lauridsen, Patricia Bloom, Dominique Thabut, Silvia Nardelli, Sara Montagnese, Christian Labenz
Journal: Journal of Hepatology (2024)
TOP-108 Evaluation of the scoring systems dedicated to liver transplantation in acute-on-chronic liver failure (ACLF) in an international multicenter cohort
Authors: Sébastien L'Hermite, José Ursic Bedoya, Sébastien Halter, Philippe Ichai, Line Carolle Ntandja Wandji, Audrey Coilly, Christophe Camus, Samir Jaber, Rhiannon Taylor, Sébastien Dharancy, Douglas Thorburn, Filomena Conti, Georges-Philippe Pageaux, Faouzi Saliba, Constantine Karvellas, Antoine Monsel, Alexandre Louvet, William Bernal, Florent Artru
Journal: Journal of Hepatology (2024)
SAT-285-YI Incorporation of cholestasis into prognostic models improves predictive outcome in alcohol-related liver disease: a retrospective multicenter study
Authors: Mohsan Subhani, Minjun Chen, Hannes Hagström, Michael Allison, Mayur Brahmania, Ewan H. Forrest, Anne McCune, Steven Masson, Neil Rajoriya, Juan Pablo Arab, Guruprasad Aithal, Richard Parker
Journal: Journal of Hepatology (2024)
THU-059 Therapeutic plasma exchange improves organ function and potentially increases short-term survival in ACLF-3 patients who do not respond to standard medical treatment: a single centre propensity score-matched retrospective study
Authors: Jonas Schumacher, Rhea Veelken, Adam Herber, Lorenz Weidhase, Raymund Buhmann, Reinhard Henschler, Sirak Petros, Thomas Berg
Journal: Journal of Hepatology (2024)
FRI-043 A multi-center randomized controlled study of primary prevention of esophageal variceal bleeding in cirrhotic patients treated with HVPG-guided therapy or standard heart rate-guided therapy: an interim analysis of the PORTHOS trial
Authors: Annelotte Broekhoven, Jelte Schaapman, Annarein Kerbert, Hein W Verspaget, Bart van Hoek, Suzanne Cannegieter, Arian van Erkel, Wilbert van den Hout, Bart Mertens, Roeland Veenendaal, Ulrich Beuers, R. Bart Takkenberg, Karin van Nieuwkerk, Johan P.H. Kuyvenhoven, Sunje Abraham, Thomas Vanwolleghem, Minneke Coenraad
Journal: Journal of Hepatology (2024)
WED-060-YI Type-I interferon shapes peritoneal immunity in cirrhosis and drives caspase-5-mediated progranulin release during spontaneous bacterial peritonitis
Authors: Michael Rooney, Shivalee Duduskar, Mohamed Ghait, Johanna Reising, Sven Stengel, Philipp Reuken, Alexander Zipprich, Michael Bauer, Ashley Russo, Vijay Rathinam, Andreas Stallmach, Ignacio Rubio, Tony Bruns
Journal: Journal of Hepatology (2024)
FRI-126 Impact of micronutrient deficiencies on the mortality of patients with cirrhosis admitted for acute decompensation
Authors: Ariadna Altadill, Gemma Llibre-Nieto, Cristina Solé, José Alberto Ferrusquía, Mireia Miquel, Meritxell Casas, Valenti Puig-Diví, Alba Lira, Berta López-Sáez, Claudia Torras, Isabel Laucirica, Andrea Peña, Carla de Sárraga, Judith Cortada, Mar Salas, Laia Grau, Mercedes Vergara, Jordi Sánchez
Journal: Journal of Hepatology (2024)