tbuckley/cabot-search huggingface dataset:
Follow-up of the Randomized ASAP Trial Shows No Survival Advantage for Patients with Poor Responsive or Relapsed AML Who Received Intensive Salvage Chemotherapy for Remission Induction Prior to Allogeneic Transplantation Compared to Immediate Allogeneic Transplantation
Authors: Matthias Stelljes, Jan Moritz Middeke, Gesine Bug, Eva-Maria Wagner Drouet, Lutz Peter Hermann Mueller, Christoph Schmid, Stefan W. Krause, Wolfgang Andreas Bethge, Edgar Jost, Uwe Platzbecker, Stefan Klein, Judith Niederland, Martin Kaufmann, Kerstin Schäfer-Eckart, Henning Baldauf, Friedrich Stölzel, Sarah Trost, Christoph Röllig, Malte von Bonin, Katharina Egger-Heidrich, Désirée Kunadt, Björn Steffen, Beate Hauptrock, Christoph Schliemann, Katja Sockel, Fabian Lang, Oliver Kriege, Judith Schaffrath, Christian Reicherts, Wolfgang E. Berdel, Hubert Serve, Gerhard Ehninger, Alexander H. Schmidt, Jan-Henrik Mikesch, Martin Bornhäuser, Johannes Schetelig
Journal: Blood (2024)
Prevalence, Genetic Predispositions and Clinical Consequences of Non-CLL-Type MBL: Screening in 10,330 Individuals
Authors: Yuan Yao, Sameer A. Parikh, Sara Achenbach, Aaron D. Norman, Kari G. Rabe, Nicholas J. Boddicker, Janet E. Olson, Rosalie Griffin, Soren Basnet, Dennis P. Robinson, Mingma Hoel, Alyssa I Clay-Gilmour, Stacey Lehman, Timothy G. Call, James R. Cerhan, Celine M. Vachon, Neil E. Kay, Esteban Braggio, Curtis A. Hanson, Tait D. Shanafelt, Susan L. Slager
Journal: Blood (2024)
Rovadicitinib in Patients with Myelofibrosis Who Were Refractory or Relapsed or Intolerant to Ruxolitinib: A Single Arm, Multicenter, Open-Label, Phase Ib Study
Authors: Chunkang Chang, Min Zhang, Sujun Gao, Luxi Song, Duoer Wu, Dawei Ding, Shanli Lao, Ding Yu
Journal: Blood (2024)
Unveiling ZMAT2 and SMARCD3 As Therapeutic Targets to Mitigate Aberrant Hematopoiesis in MDS
Authors: Aintzane Diaz-Mazkiaran, Jesús de la Fuente, Guillermo Serrano, Paula Garcia-Olloqui, Nerea Berastegui, Marina Ainciburu, Ana Alfonso Pierola, Amaia Vilas-Zornoza, Patxi San-Martin, Jose Maria Lamo-Espinosa, Mikel San-Julian, Pamela Acha, Tamara Jimenez, Antonieta Molero, Maria Julia Montoro, Francesc Sole, Maria Diez-Campelo, David Valcarcel, Irene Ganan-Gomez, Felipe Prosper, Mikel Hernaez, Teresa Ezponda
Journal: Blood (2024)
Outcomes of Elderly Patients with Relapsed Refractory Multiple Myeloma (RRMM) Treated with Teclistamab: A Multicenter Study from the U.S. Multiple Myeloma Immunotherapy Consortium
Authors: Oren Pasvolsky, Danai Dima, Lei Feng, Wenli Dong, Tiffany Richards, James A Davis, Aimaz Afrough, Mariola A Vazquez-Martinez, Aishwarya Sannareddy, Utkarsh Goel, Rahul Banerjee, Jack Khouri, Frances N. Cervoni Curet, Mahmoud R. Gaballa, Alex Lieberman-Cribbin, Masooma S Rana, Kelley Julian, Christopher J Ferreri, Leyla O. Shune, Shaun DeJarnette, Evguenia Ouchveridze, Sandra Susanibar-Adaniya, Andrew J. Portuguese, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Adriana Rossi, Megan M Herr, Daniel Schrum, Chenyu Lin, Shahzad Raza, Yi Lin, Shebli Atrash, Joseph P. McGuirk, Douglas W Sborov, Peter M. Voorhees, Faiz Anwer, Melissa Alsina, Ciara Louise Freeman, Alfred L. Garfall, Surbhi Sidana, Andrew J. Cowan, Larry D Anderson, Doris K. Hansen, Shambavi Richard, Krina K. Patel, Hans C. Lee, Ariel Grajales-Cruz
Journal: Blood (2024)
Gilteritinib Results in Higher Remission and Transplant Rates Than Midostaurin but Does Not Increase the Post-Induction Mutational MRD Negative Rate: Results of the Phase 2 Randomized Precog 0905 Study in Newly Diagnosed <i>FLT3</i> Mutated AML
Authors: Selina Luger, Li Chen, Keith W. Pratz, Sanam Loghavi, Alexander E. Perl, Jessica K. Altman, Robert L. Redner, Amir T. Fathi, Ayman Qasrawi, Adam S. Asch, Deepa Jeyakumar, James M. Foran, Mithun V Shah, Jonathan E Kolitz, Ellin Berman, Lindsay Wilde, Sameem Abedin, Vamsi K. Kota, Krishna Gundabolu, Kristen M. O'Dwyer, Emily K Curran, Ashwin Kishtagari, Kelly Ross, Zhuoxin Sun, Mark R. Litzow
Journal: Blood (2024)
Prognostic Value of Response to First-Line Hydroxyurea According to Ipset Stratification in Essential Thrombocythemia
Authors: Marta Santaliestra, Marta Garrote, María Soledad Noya, Manuel Pérez-Encinas, María Alicia Senin, Raul Perez Lopez, Francisca Ferrer Marin, Gonzalo Carreño, Gonzalo Caballero Navarro, Elena Magro, Patricia Velez, Miguel A. Cortes Vázquez, Ana Moreto Quintana, Anna Angona, Irene Pastor Galan, Jose María Guerra, M. Carmen Garcia Hernandez, María Isabel Mata, Ruth Stuckey, Maria Teresa Gómez Casares, Maria Laura Fox, Beatriz Cuevas, Valentín García Gutiérrez, Ana Triguero, Eduardo Arellano-Rodrigo, Juan Carlos Hernandez Boluda, Alberto Alvarez-Larran
Journal: Blood (2024)
Interim Results from a Phase 2 Pivotal Study (DALY II USA) of Tandem CD20-CD19-Directed Non-Cryopreserved CAR-T Cells - Zamtocabtagene Autoleucel (Zamto-Cel) in Patients with Relapsed/Refractory Diffuse Large B Cell Lymphoma
Authors: Nirav N. Shah, Richard T. Maziarz, Caron A. Jacobson, Patrick B. Johnston, Sunil Abhyankar, Iris Isufi, Miguel Angel Perales, Monalisa Ghosh, Matthew Ulrickson, Allison C. Rosenthal, Javier L. Munoz, Nancy M. Hardy, Aaron P. Rapoport, Reem Karmali, Farrukh T. Awan, Matthew Stuart McKinney, Mitchell Horwitz, Matthew Lunning, Nathan Denlinger, Marek Ancukiewicz, Madhavi Nallewar, Kimberly C Coleman, Esther Eromosele, Remigiusz Kaleta, Johanna Theruvath, Anna Wijatyk, David B. Miklos
Journal: Blood (2024)
Preliminary Efficacy and Safety of the Bruton Tyrosine Kinase Degrader BGB-16673 in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Results from the Phase 1 CaDAnCe-101 Study
Authors: Meghan C. Thompson, Ricardo D. Parrondo, Anna Maria Frustaci, John N. Allan, Paolo Ghia, Irina Mocanu, Constantine S. Tam, Judith Trotman, Inhye E. Ahn, Stephan Stilgenbauer, Lydia Scarfo, Xiangmei Chen, Kunthel By, Shannon Fabre, Daniel O. Persky, Amit Agarwal, John F. Seymour
Journal: Blood (2024)
Elevated Clonal Hematopoiesis in Environmentally Exposed Responders Has Distinct Age-Related Patterns and Relies on IL1RAP for Clonal Expansion
Authors: Divij Verma, Rachel Zeig Owens, David G Goldfarb, Kith Pradhan, Srabani Sahu, Susheian Kelly, Orsi Giricz, Sakshi Jasra, Yiyu Zou, Colette Prophete, Lidiane Torres, Srinivas Aluri, Samarpana Chakraborty, Shanisha Gordon Mitchell, Rajni Kumari, Jingli Wang, Alexander J Silver, Charles Hall, Ryan Bender, Ola Landgren, Lee Greenberger, Advaitha Madireddy, Aditi Shastri, Lindsay Lafave, Anna Nolan, Michael R. Savona, Ulrich Steidl, David Prezant, Amit Verma
Journal: Blood (2024)
Deciphering the Mechanism of Action of the Novel Celmod, Golcadomide, during Germinal Center B Cell Immune Response and in a Preclinical Mouse Model of Follicular Lymphoma
Authors: Caroline Huber, Yumi Nakayama, Camille Soun, Noushin Mossadegh-Keller, Sophie Guia, Melanie Collin, Alexandre Sarrabay, Lionel Chasson, Lionel Spinelli, Bertrand Nadel, Anita K. Gandhi, Gabriel Brisou, Patrick R. Hagner, Sandrine Roulland
Journal: Blood (2024)
Prognostic Impact of t(1;19) in Pediatric B-Cell Acute Lymphoblastic Leukemia (B-ALL) Patients Treated on Contemporary Children's Oncology Group (COG) Protocols
Authors: Ashley Pinchinat, John A. Kairalla, Meenakshi Devidas, Andrew J. Carroll, Mary Shago, Anne Angiolillo, Michael J. Burke, Wanda L. Salzer, Naomi J. Winick, Mignon L. Loh, David T. Teachey, Elizabeth A. Raetz, Karen R Rabin, Rachel E. Rau, Sumit Gupta
Journal: Blood (2024)
Longitudinal Single-Cell Immune Profiling Reveals Distinct Dynamics of Response to Teclistamab in Patients with High-Risk Smoldering Myeloma Compared to Relapsed-Refractory Multiple Myeloma
Authors: Nayda Bidikian, Francesco Corrado, Romanos Sklavenitis-Pistofidis, Yoshinobu Konishi, Rosa Toenges, Jean-Baptiste Alberge, Michelle P. Aranha, Ting Wu, Michael Timonian, Shonali Midha, Elizabeth K. O'Donnell, Yuxin Liu, Sophie Magidson, Ashlee Strutevant, Kenneth C. Anderson, Nikhil C. Munshi, Omar Nadeem, Gad Getz, Irene Ghobrial
Journal: Blood (2024)
CD70 Deregulation in Follicular Lymphoma at Diagnosis Is Associated with Relapse and Opens New Avenues for Dual CD19-CD70 CAR-T Therapy
Authors: Ferran Araujo-Ayala, Maria Ros, Mireia Bachiller, Raluca Alexandru, Pablo Mozas, Salut Colell, Judith Mateos-Jaimez, Cristina López, María Villalba-Esparza, Ferran Nadeu, Andrea Rivero, Cèlia Dobaño-López, Juan Garcia Valero, Neus Serrat, Marta Gimenez-Alejandre, Ariadna Giró, Daniel J Hodson, Armando Lopez-Guillermo, Elias Campo, Dolors Colomer, Alba Maiques-Diaz, Jose Ignacio Martin-Subero, Silvia Bea, Laura Magnano, Sonia Guedan, Carlos Eduardo De Andrea, Patricia Perez Galan
Journal: Blood (2024)
T-Cell Transcriptomic Signatures in Adults with Primary Untreated Immune Thrombocytopenia Segregate By Age, Revealing Distinct Druggable Pathways
Authors: Lipei Shao, Aaron Boothby, S. Lawrence Bailey, Aastha Chauhan, Martin Boechenek, Terry B. Gernsheimer, John W. Semple, James L. Zehnder, V. Koneti Rao, Jin Ping, David F. Stroncek, Moritz Stolla, Sandya R. Panch
Journal: Blood (2024)
Leveraging Population-Scale Multiomic Datasets to Elucidate the Risk of Thrombosis Associated with Protein S (<i>PROS1</i>) Deficiency
Authors: Sharjeel A Chaudhry, Amelia K Haj, Justine Ryu, Sean J. Jurgens, Alfonso Rodriguez Espada, Xin Wang, Seung Hoan Choi, Simone Sanna-Cherchi, Kenneth A Bauer, Patrick Ellinor, Pavan K Bendapudi
Journal: Blood (2024)
GEM2017Fit Phase 3 Trial in Fit Elderly Patients (Aged 65-80) with Newly Diagnosed Myeloma: Impact of Daratumumab at Induction and/or Consolidation
Authors: Maria- Victoria Mateos, Bruno Paiva, Maria Teresa Cedena Romero, Noemi Puig, Anna Sureda Balari, Albert Oriol, Enrique M Ocio, Laura Rosiñol, Yolanda González-Montes, Joan Bargay, Esther Gonzalez Garcia, Miguel Teodoro Hernández Garcia, Angel Ramirez, Alexia Suarez-Cabrera, María-Jesús Blanchard, Sebastián Garzón, Luis Felipe Casado, Valentin Cabanas Perianes, Jaime Perez de Oteyza, Mercedes Gironella, Joaquin Martínez-López, Ana-Isabel -Teruel, Pilar Delgado, Elena Prieto, Juan-Jose Lahuerta Palacios, Joan Bladé, Jesús F. San-Miguel
Journal: Blood (2024)
Personalized Transplant Decision Making for Myelofibrosis in the Era of Molecular Genetics and JAK Inhibition
Authors: Nico Gagelmann, Barbara Mora, Filippo Branzanti, Alessandro Maria Vannucchi, Massimo Breccia, Giuseppe Alberto Maria Palumbo, Massimiliano Bonifacio, Erika Morsia, Elena Maria Elli, Mario Tiribelli, Giulia Benevolo, Mirko Farina, Fabrizio Pane, Roberto Massimo Lemoli, Giovanni Caocci, Alessia Tieghi, Gianni Binotto, Francesco Cavazzini, Bruno Martino, Alessandro Isidori, Margherita Maffioli, Elisa Rumi, Tiziano Barbui, Francisco Cervantes, Matteo Giovanni Della Porta, Andrew T. Kuykendall, Marianna Caramella, Alessandra Iurlo, Valerio De Stefano, Jean-Jacques Kiladjian, David Ross, Jason Gotlib, Timothy Devos, Marco Ruggeri, Richard T. Silver, Rachel B. Salit, Thomas Schroeder, Carmelo Gurnari, Simona Pagliuca, Christina Rautenberg, Marie Robin, Marie-Thérèse Rubio, Jaroslaw Maciejewski, Alessandro Rambaldi, Maria Chiara Finazzi, Andrea Bacigalupo, Patrizia Chiusolo, Hans Christian Reinhardt, Bart L. Scott, Nicolaus Kröger, Francesco Passamonti, Francesca Palandri
Journal: Blood (2024)
Autosomal Recessive COPZ1 Mutations Cause Isolated Severe Neutropenia or Complex Syndrome with Severe Neutropenia
Authors: Natalia Alejandra Borbaran Bravo, Ekaterina Deordieva, Larissa Doll, Mohammad Elgamacy, Benjamin Dannenmann, Joana Azevedo, Alberto Iannuzzo, Selket Delafontaine, Moritz Lehners, Marius Kolodziej, Birte Hernandez Alvarez, Anna-Sophia Hellmuth, Malte Ulrich Ritter, Betül Findik, Viktoria Zakharova, Sandro Bräuning, Sergey Kandabarau, Claudia Lengerke, Robert Feil, Isabelle Meyts, Jerome Delon, Markus Templin, Marc Sturm, Olaf Rieß, Cornelia Zeidler, Karl Welte, Anna Shcherbina, Maksim Klimiankou, Julia Skokowa
Journal: Blood (2024)
Impact of Socioeconomic Factors on Access to and Outcomes of Allogeneic Hematopoietic Cell Transplantation (allo-HCT) for Acute Myeloid Leukemia (AML): A Multi-Center Observational Study
Authors: Natalie Wuliji, Ted Gooley, Salene Jones, Aaron T. Gerds, Bruno Medeiros, Paul J. Shami, John Galvin, Kehinde Adekola, Selina Luger, Maria R. Baer, David A. Rizzieri, Tanya M. Wildes, Eunice S. Wang, Mikkael A. Sekeres, Sudipto Mukherjee, Julie C. Smith, Mitchell A. Garrison, Kiarash Kojouri, Jacob S. Appelbaum, Mary-Elizabeth M. Percival, Brenda M. Sandmaier, Frederick R. Appelbaum, Mohamed Sorror
Journal: Blood (2024)
Overcoming Ven/Aza Resistance through Imetelstat-Mediated Lipophagy in Acute Myeloid Leukemia
Authors: Claudia Bruedigam, Eunice Anne Dulatre, Carol Lee, Amy H Porter, Elisa LSP Lim, Alexander Z Shi, Mark P Hodson, Florian H. Heidel, Steven W Lane
Journal: Blood (2024)
Updated Clinical Results: A Multicenter, Open-Label, Phase 3 Study of Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Recipients with Epstein-Barr Virus-Driven Post Transplant Lymphoproliferative Disease after Failure of Rituximab or Rituximab Plus Chemotherapy
Authors: Armin Ghobadi, Robert Baiocchi, Amer M. Beitinjaneh, Sridhar Chaganti, Sylvain Choquet, Daan Dierickx, Rajani Dinavahi, Xinyuan Duan, Laurence Gamelin, Kris Michael Mahadeo, Aditi Mehta, Sarah Nikiforow, Ran Reshef, Sandrine Roye, Jean-Claude Vedovato, Susan E Prockop
Journal: Blood (2024)
A Randomised Comparison of CPX-351 Versus Standard Daunorubicin and Cytarabine Plus Fractionated Gemtuzumab Ozogamicin in Older Adults with AML without Adverse Risk Cytogenetics: Results of the NCRI AML18 Trial
Authors: Steven Knapper, Laura W Dillon, Malavika Babu, Abin Thomas, Ian Thomas, Christopher S. Hourigan, Georgia Andrew, Richard Dillon, Amanda Gilkes, Nuria M Almuina, Sophie King, Thomas Coats, Nicholas McCarthy, Jennifer Byrne, Simone Green, Ulrik Malthe Overgaard, Leanne Berkahn, Louisa Stone, Rasha W Al-Ali, Reem Bahr, Rob Sellar, Mike Dennis, Priyanka Mehta, Robert K Hills, Sylvie D Freeman, Nigel H. Russell
Journal: Blood (2024)
Nx-2127 and Nx-5948, Two Clinical Stage Cereblon-Recruiting BTK Degraders, Facilitate T Cell Functionality in Chronic Lymphocytic Leukemia
Authors: Tiana Huynh, Sonia Rodriguez-Rodriguez, Carly Roleder, Sarah Whelan, May Tan, Ernestine Lee, Paul Munson, Alexey V. Danilov
Journal: Blood (2024)
CD117 Antibody Conditioning and Multiplex Base Editing Enable Rapid and Robust Fetal Hemoglobin Reactivation in a Rhesus Autologous Transplantation Model
Authors: Selami Demirci, Nandini Mondal, Wayne Austin, Henna Butt, Evan London, Shruti Sathish, Kathy Zhang, Jeffrey Wong, Hugh Kromer, Alexander Harmon, Jeremy Decker, Anh Le, Khaled Essawi, Allen E Krouse, N Seth Linde, Aylin Bonifacino, Theresa Engels, Justin Golomb, So Gun Hong, Naoya Uchida, Nicole Gaudelli, Adam J. Hartigan, Charlotte F McDonagh, S Haihua Chu, Robert E Donahue, John Tisdale
Journal: Blood (2024)
Critical Bleeding in Adults and Children with Immune Thrombocytopenia: A Multicentre Cohort Study
Authors: Saifur R. Chowdhury, Emily Sirotich, Dimpy Modi, Melanie St John, Kerolos Eisa, Adam Cuker, Carolyn E Beck, Rachael F Grace, Shuoyan Ning, Justin W Yan, Amanda Pfeiffer, Michele P Lambert, Karen Panckeri, Allyson M Pishko, Kristine VanAarsen, Ahmed Slim, Kathryn M. Carrier, Rebecca Geer, Abinaya Arulselvan, Matthew Basara, Brenna Cannon, Ellis Bloom, Sam J King, Daya Gill, Laura M. Venier, Emily Xu, Ishaq Siddiqui, Bonnie Liu, Taylah Buissereth, Timothy Mercier, Emily M. Harris, Enass H. Raffa, Joel Livingston, Dongyoung Kim, Maryam Akbari-Moghaddam, Gordon Guyatt, Dena Zeraatkar, Lehana Thabane, Donald Arnold
Journal: Blood (2024)
Pathogenesis and Clinical Relevance of Diffuse Large B-Cell Lymphoma Proteogenotypes
Authors: Julius C. Enssle, Björn Häupl, Arber Qoku, Boya Wang, George W. Wright, Sharon Barrans, Matthew Anthony Care, Cathy Burton, Caitlin Gribbin, Sebastian Scheich, Sebastian Wolf, James D. Phelan, Da Wei Huang, Andrea diFonzo, Martine Pape, Marion Bodach, Dominique Jahn, Uwe Plessmann, Daniel J Hodson, Bernhard Kuster, Roland Schmitz, Henning Urlaub, Reuben Tooze, Giorgio Inghirami, Florian Buettner, Louis M. Staudt, Thomas Oellerich
Journal: Blood (2024)
Spatial Architecture of Immune Microenvironment Orchestrating Anti-Lymphoma Immunity and the Response to Immunochemotherapy in EBV+ Diffused Large B Cell Lymphoma Revealed By Imaging Mass Cytometry and Spatial Transcriptome
Authors: Zhijuan Lin, Xingxing Yu, Yan Hong, Long Liu, Zhifeng Li, Jie Zha, Bing Xu
Journal: Blood (2024)
Romidepsin, Azacitidine, Dexamethasone, and Lenalidomide (RAdR) for Relapsed/Refractory T-Cell Lymphoma
Authors: Max J Gordon, Milos D Miljkovic, Samuel Ng, Rahul Lakhotia, Christopher Melani, Kevin Conlon, James D. Phelan, Bonita Bryant, Laura M Yee, Stefania Pittaluga, Elaine S. Jaffe, Louis M. Staudt, Wyndham H. Wilson, Mark Roschewski
Journal: Blood (2024)
Prolonged Persistence and Functional Activity of Anti-BCMA CAR-T Durcabtagene Autoleucel (PHE885) Manufactured Using the T-Charge™ Platform
Authors: Shuntaro Ikegawa, Adam S. Sperling, Sarah Nikiforow, Andrew Ghazi, Anthony Christidis, David Quinn, Dexiu Bu, Jennifer Mataraza, David Pearson, Allison Charles, Marc Credi, Nina Orwitz, Madisyn Strange, Rakuyo Tamada, Kevin M. Panaro, Casey Gervais, Michela Ansuinelli, Yohei Arihara, Rao Prabhala, Carol G. Reynolds, Robert Gentleman, Serena De Vita, Nikhil C. Munshi, Jerome Ritz
Journal: Blood (2024)
Improving Guideline Concordant Primary Prevention Aspirin Use through a Multiclinic Antithrombotic Stewardship Intervention
Authors: Jordan K Schaefer, Naina Chipalkatti, Linda Bashaw, Adam Davie, Joelle Ellis, Molly Harrod, Jacob E Kurlander, Christine Medaugh, Rebeca Packard, Corey Powell, Suman L Sood, Elizabeth Spranger, Sarah Vordenberg, Geoffrey D Barnes
Journal: Blood (2024)
Modulation of the Tumor Microenvironment By CCL19 in Primary CNS Lymphomas
Authors: Julia C. Kuehn, Roman Sankowski, Nicolas N. Neidert, Elena Grabis, Jurik A. Mutter, Stefan K. Alig, Junyi Zhang, Christian Klingler, Lavanya Ranganathan, Fabian Hummel, Sabine Bleul, Eliza M. Lauer, Dieter Henrik Heiland, Marco Prinz, Katharina J. Müller, Louisa von Baumgarten, Justus Duyster, Elisabeth Schorb, Maximilian Diehn, Ash A. Alizadeh, Peter C. Reinacher, Florian Scherer
Journal: Blood (2024)
The Transcriptional Activators p300/Crebbp Are Context-Dependent Functional Repressors of Interferon Genes, Offering Therapeutic Promise in AML
Authors: Markus Meyerhöfer, Viral Shah, Aarón Gallego-Crespo, Malte Andreas Behrendt, Yawen Zhou, Maria Saura-Pañella, Björn Häupl, Thomas Kindler, Matthias Theobald, Falk Butter, George S Vassiliou, Michael Kühn, Brian J P Huntly, Thomas Oellerich, Daniel Sasca
Journal: Blood (2024)
Longitudinal Clonal Tracking Reveals That Early and Sensitive Detection of Blood Cancer-Related Gene Variants in Patients with Chronic Myeloid Leukemia Predicts Treatment Failure
Authors: Susan Branford, Adelina Fernandes, Carol Wadham, Muneeza Maqsood, Nur Hezrin Shahrin, David M Ross, Agnes S. M. Yong, Ming Lin, Rosalie Kenyon, Dominik Kaczorowski, Verity A Saunders, Ilaria Stefania Pagani, John Toubia, Joe McConnell, David T Yeung, Chung Hoow Kok, Timothy P Hughes, Naranie Shanmuganathan
Journal: Blood (2024)
Genomic Determinants of Resistance to Anti-BCMA Chimeric Antigen Receptor T-Cell (CART) Therapies in Patients with Relapsed/Refractory Multiple Myeloma
Authors: Francesco Maura, Ciara Louise Freeman, Holly Lee, Kylee H Maclachlan, Michael Durante, Bachisio Ziccheddu, Meghan Menges, Benjamin Diamond, Marios Papadimitriou, Ariosto Siqueira Silva, Praneeth Reddy Sudalagunta, Noemie Leblay, Sungwoo Ahn, Ethan Fuller, Edward Briercheck, Phaedra Agius, Doris K. Hansen, Xiaofei Song, Xiaohong Zhao, Mark B. Meads, Jamie Teer, Ross S Firestone, Juan-Jose Garces, Tomas Jelinek, Rachid Baz, Melissa Alsina, Anusuyam Ramasubramanian, Eric Smith, Sergio Giralt, Sham Mailankody, Paola Neri, Saad Z. Usmani, Frederick Locke, Nizar J. Bahlis, Ola Landgren, Kenneth H. Shain
Journal: Blood (2024)
Trial Update from IMproveMF, an Ongoing, Open-Label, Dose-Escalation and -Expansion, Phase 1/1B Trial to Evaluate the Safety, Pharmacokinetics, and Clinical Activity of the Novel Combination of Imetelstat with Ruxolitinib in Patients with Intermediate-1, Intermediate-2, or High-Risk Myelofibrosis (MF)
Authors: John O. Mascarenhas, Salman Otoukesh, Terrence Bradley, Bart L. Scott, Habte A. Yimer, Souria Dougherty, Lixian Peng, Fei Huang, Ying Wan, Faye M. Feller, Vivian Rodolf, Judy Ho, Tymara Berry, Andrew T. Kuykendall
Journal: Blood (2024)
Efficacy and Toxicity of Fixed Dose Versus Reduced/PK-Adjusted Dose Pegaspargase in Pediatric Patients with Newly Diagnosed Acute Lymphoblastic Leukemia: Results of DFCI ALL Consortium Protocol 16-001
Authors: Melissa A. Burns, Yael Flamand, Lynda M. Vrooman, Victoria B. Koch, Yves Theoret, Sarah M. Cronholm, Sarah K. Hunt, Peter D. Cole, Lisa M. Gennarini, Nobuko Hijiya, Justine M. Kahn, Kara M. Kelly, Bruno Michon, Donna S. Neuberg, Andrew E. Place, Thai Hoa Tran, Jennifer J.G. Welch, Stephen E. Sallan, Lewis B. Silverman
Journal: Blood (2024)
Phase 3 Study of Teclistamab (Tec) in Combination with Lenalidomide (Len) and Tec Alone Versus Len Alone in Newly Diagnosed Multiple Myeloma (NDMM) As Maintenance Therapy Following Autologous Stem Cell Transplantation (ASCT): Safety Run-in (SRI) Results from the Majestec-4/EMN30 Trial
Authors: Elena Zamagni, Tobias Silzle, Ivan Špička, Sabrin Tahri, Sarah Lonergan, Inger S. Nijhof, Antonietta Pia Falcone, Evangelos Terpos, Jakub Radocha, Roberto Mina, Guldane Cengiz Seval, Meral Beksac, Cesar Rodriguez, Marcelo C. Pasquini, Michel Delforge, Vania Hungria, Donna Reece, Philippe Moreau, Yael C. Cohen, Kihyun Kim, Dominik Dytfeld, Jiří Minařík, Irene Strassl, Jelena Bila, Martin Schreder, Janusz Krawczyk, Fredrik Schjesvold, Caroline Cicin-Sain, Christoph Driessen, Gordon Cook, Lugui Qiu, Gonzalo Martin Garate, Agoston Gyula Szabo, Roman Hájek, Marc S. Raab, Silvia Mangiacavalli, Hermann Einsele, Andrew Spencer, Mario Boccadoro, Helen Vassalou, Lixia Pei, Yingqi Shi, Maria Krevvata, Ryan Gruber, Caline Sakabedoyan, Margaret Cobb, Jagoda Jasielec, Himal Amin, Rachel Kobos, Pieter Sonneveld, Niels W.C.J. van de Donk
Journal: Blood (2024)
Multicenter, Open-Label Phase 1/2a Study of Pxs-5505 and Ruxolitinib in Patients with Primary, Post-Polycythemia Vera (PV) or Post-Essential Thrombocythemia (ET) Myelofibrosis
Authors: Peter Tan, Ross Baker, Sung-Eun Lee, Anne Marie Watson, Stanley Cheung, Shang-Ju Wu, Chih-Cheng Chen, Shuhying Tan, Pankit Vachhani, Tsai-Yun Chen, Jae Hoon Lee, Hui-Hua Hsiao, Ji Yun Lee, Won Sik Lee, Lucia Masarova, Jana Baskar, Wolfgang Jarolimek, Joanna Leadbetter
Journal: Blood (2024)
A Randomized Phase II Study of Mosunetuzumab SC Plus Polatuzumab Vedotin Demonstrates Improved Outcomes Versus Rituximab Plus Polatuzumab Vedotin in Patients (Pts) with Relapsed or Refractory (R/R) Large B-Cell Lymphoma (LBCL)
Authors: Julio C. Chavez, Adam J. Olszewski, Mariana Bastos-Oreiro, Sarit E. Assouline, Izidore S. Lossos, Catherine Diefenbach, Nilanjan Ghosh, Dipenkumar Modi, Waleed Sabry, Seema Naik, Nirav N. Shah, Ronan Foley, Daniel J Hodson, Sneha Makadia, Song Pham, Elicia Penuel, Hao Wu, Wahib S. Ead, Iris To, Connie Lee Batlevi, Michael C. Wei, L. Elizabeth Budde
Journal: Blood (2024)
CXCR4 Antagonism Corrects Peripheral Neutropenia and Mature Neutrophil Accumulation in Bone Marrow in a Pharmacological Mouse Model of CXCR2 Loss-of-Function
Authors: Chi Huu Nguyen, Robert Johnson, Katarina Zmajkovicova, Angelina Sekirnik, Sarah Taplin, Myriam Defontis, Jacob R. Bledsoe, Lars Karlsson, Arthur G. Taveras
Journal: Blood (2024)
High IGHV Intraclonal Diversification Identifies CLL with Good Prognosis, Features of Anergy and Specific T-Cell Profiles
Authors: Filippo Vit, Tamara Bittolo, Antonella Zucchetto, Robel Papotti, Erika Tissino, Federico Pozzo, Andrea Stacchetti, Francesca Rossi, Massimo Degan, Eva Zaina, Ilaria Cattarossi, Paola Varaschin, Paola Nanni, Michele Berton, Alessandra Braida, Roberta Laureana, Annalisa Chiarenza, Jacopo Olivieri, Azzurra Anna Romeo, Annalisa Biagi, Giovanni D'Arena, Enrica Antonia Martino, Pietro Bulian, Massimo Gentile, Massimiliano Postorino, Laura Ballotta, Francesco Zaja, Francesco Di Raimondo, Maria Ilaria Del Principe, Valter Gattei, Riccardo Bomben
Journal: Blood (2024)