The Global Kidney Patient Trials Network and the CAPTIVATE Platform Clinical Trial Design
Authors: Sradha S. Kotwal, Vlado Perkovic, Meg J. Jardine, Dana Kim, Nasir A. Shah, Enmoore Lin, Sarah Coggan, Laurent Billot, Priya Vart, David C. Wheeler, Ian H. de Boer, Hong Zhang, Fan Fan Hou, Yuka Sugawara, Joseph Marion, Roger J. Lewis, Lindsay R. Berry, Anna McGlothlin, Vivekanand Jha, Luca De Nicola, Jose L. Gorriz, Hiddo J. L. Heerspink, Andres Alvarisqueta, Julio Bittar, Natalia Cluigt, Judith Gaite, Luis Gaite, Silvia Marcela Maurich, Pablo Ramallo, Alejandra Quevedo, Carlos Arias, Jorge Hector Resk, Mariana Brusa, Paula Andrea Marioli, Lawrence McMahon, Sridevi Govindarajulu, Nicholas Gray, Simon Roger, Adam Flavell, Suda Swaminathan, Nigel Toussaint, Jessica Stranks, Peak Mann Mah, Parind Vora, Serge Cournoyer, Marie-France Langlois, Matthew Weir, Fan Fan Hou, Hong Zhang, Zhihong Liu, Wang Caili, Luo Qun, Kong Yaozhong, Fu Ping, Xiong Zuying, Lu Wanhong, Li Guisen, Menghua Chen, Li Peng, Yiwen Liu, Cheng Hong, Jianqin Wang, Dong Junwu, Ma Zhigang, Yan Rui, Shi Yongjun, Zhang Chun, Lv Xueai, Yu Xiaoyong, Bian Xueyan, Yihua Bai, Maura Ravera, Antonio Pisani, Mariacristina Gregorini, Ciro Esposito, Filippo Aucella, Luca De Nicola, Felice Nappi, Cataldo Abaterusso, Loreto Gesualdo, Michele Andreucci, Mariadelina Simeoni, Seiji Itano, Naoki Kashihara, Jun Wada, Yuka Sugawara, Masaomi Nangaku, Motoji Naka, Masahiko Takai, Shin Goto, Ichei Narita, Masafumi Fukagawa, Takashi Yokoo, Shinya Kaname, Abe Masanori, Yusuke Suzuki, María Jose Soler Romeo, Emma Pardo, Alfonso Soto Gonzalez, Josep Maria Cruzado, Jose Luis Górriz, Secundino Cigarran, Fernando Cereto Castro, Jonay Pantoja Perez, Cristobal Morales Portillo, Francisco Jose Tinahones Maduen, Maria Marques, Roberto Pecoits-Filho, Sergio Rovner, Ahmed Arif, Pablo Pergola, Tuan-Huy Tran, Manuel Montero    , Jamal Hammoud, Michael Shanik, Pedro Andres Velasquez-Mieyer, Katherine Jean Lucas, James Franklin, Arthur Green, Andrew Drabick, Joseph Alello, Robert Busch, Nina Patel, Sanjay Vora, Osvaldo A. Brusco, Jose Gomez-Cortez, Csaba Kovesdy, Ian de Boer, Radica Alicic, Eric Kirk, Nauman Shahid, Anand Reddy, Pedro Hernandez, Ronald Mayfield, Linda Schneider, Brian Layden, Gerard Bueso, Margaret Yu, Vinod Malhotra, Billy Hour, Kianoosh Kaveh, Visal Numrungroad, Reginald Gohh, Jose Santiago, Shaunak Dwivedi, Steven Ong, Marwan Edris, Anant Desai, Marina Gold, Bram Wieskopf, Sradha Kotwal, Hiddo Lambers Heerspink, Enmoore Lin, Sarah Coggan, Farjarneh Hossain, Shengkun Sun, Fan Han Hsu, Emma Dombroski, Maria Ali, Luc Cambon, Ling Yap, Mai Ly, Justine Chua, Dominic Mounsey, Naomi Tsukada, Alina Yoffe, Francisco Achiaga, Clara Mok, Emily Walker, Ann Reid, Masego Johnstone, Charles Czank, Lisa Rominger, Paula Cisternas, Daniel Rizzi, Joy Ola, David Garcia, Jessica Cox, Osha Nelson, Lyndal Hones, Melinda Ho, Melissa Tutt, Fred Beusenberg, Radhika Kanade, Eunice Raymond, Ron Hamilton, Christine Adeyari, Yuehan Zheng, Joyce Chow, Stephanie Pollard, Enrico Chiari, Olga Cabrerizo, Denison Bowman, Yiping Xiao, Xuejie Bai, Joe Zhou, Divya Lokesh, Larry Larsheid, Naveed Shabbir, Dana Hurndon, Renee Garmack, Liza Shilpakar, Jennifer Casulla, Hui Ping Cha, HyeRyun Jin, Diane Lickey, Jin Long, Lingling Bie, Helen Monaghan, Clare Arnott, Gian Luca di Tanna, Vicky Grey, Rathika Krishnasamy, Dean Guinness, Jeremy Halewood, David Ioasa, Zhangyi He, Farjaneh Hossain, Ben Varley, Sima Don, Nursafwana (Saffy) Zulkhernain, Michelle Kim, Victoria Gregory
Journal: JAMA Network Open (2024)

Chronic kidney disease (CKD) is a global health priority affecting almost 1 billion people. New therapeutic options and clinical trial innovations such as adaptive platform trials provide an opportunity to efficiently test combination therapies.