SOME OF THE RECENT BIOCHEMICAL CONCEPTS OF GASTRIC SECRETION AND THEIR APPLICATION TO CLINICAL MEDICINE
Authors: Lay Martin
Journal: Annals of Internal Medicine (1938)

Article1 November 1938SOME OF THE RECENT BIOCHEMICAL CONCEPTS OF GASTRIC SECRETION AND THEIR APPLICATION TO CLINICAL MEDICINELAY MARTIN, F.A.C.P.LAY MARTIN, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-5-614 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis paper is presented to summarize the data on gastric secretion which have originated from this department and which have been reported in a series of articles extending over several years. The investigation was undertaken with the idea of attempting to clarify some of the moot points in connection with the changes in the acid-base pattern of human gastric secretion; to learn, if possible, the secretory concentration of hydrochloric acid and of the neutral chlorides; to determine, if possible, the type of cell or cells secreting these neutral chlorides; and to study the inorganic phosphates during various phases of secretion....Bibliography1. MARTINMORGANSTERNCARROLL LMML: Gastric secretion—the electrolytes before and their changes at various periods after histamine stimulation, ANN. INT. MED., 1932, vi, 91-128. Idem: Acid-base balance of gastric juice, blood and urine before and at intervals after stimulation of the gastric juice by histamine, Bull. Johns Hopkins Hosp., 1934, lv, 57-80. Google Scholar2. HELMER OM: Relation of secretion of mucus to acidity of gastric juice, Am. Jr. Physiol., 1934, cx, 28-36. CrossrefGoogle Scholar3. BOLDYREFF W: The self-regulation of the acidity of the gastric contents and the real acidity of the gastric juice, Quart. Jr. Exper. Physiol., 1915, viii, 1. Google Scholar4. MACLEANGRIFFITHS HWJ: The factors influencing the concentrations of hydrochloric acid during gastric digestion, Jr. Physiol., 1928, lxv, 63. CrossrefGoogle Scholar5. HOLLANDER F: Studies in gastric secretion. IV. Variations in the chlorine content of gastric juice and their significance, Jr. Biol. Chem., 1932, xcvii, 585. CrossrefGoogle Scholar6. MARTIN L: Gastric juice. I. Studies on the proteins of the gastric juice of humans, Jr. Biol. Chem., 1933, cii, 113-130. CrossrefGoogle Scholar7. Idem: Gastric juice. II. Studies on the urea-splitting enzyme and pepsin in relation to the proteins, Ibid., 1933, cii, 131-136. Idem: Studies on an urea-splitting enzyme found in gastric juice, Bull. Johns Hopkins Hosp., 1933, lii, 166-172. Google Scholar8. Idem: Total nitrogen and non-protein nitrogen partition of gastric juice obtained after histamine stimulation, Ibid., 1931, xlix, 286. Idem: Protein nitrogen and non-protein nitrogen partition of gastric juice. A clinical evaluation, Jr. Am. Med. Assoc., 1933, c, 1475. Google Scholar9. Idem: Recent investigations permitting a new interpretation of the results of the conventional titration of gastric juice, Am. Jr. Digest. Dis. and Nutr., 1934, i, 330. Google Scholar10. KEEFERBLOOMFIELD CSA: The significance of gastric secretion, Bull. Johns Hopkins Hosp., 1926, xxxix, 304. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Baltimore, Maryland*Read at St. Louis meeting of the American College of Physicians, April 23, 1937.From the Gastro-intestinal Division of the Department of Medicine of the Johns Hopkins University and Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAbstracts 1 November 1938Volume 12, Issue 5Page: 614-623KeywordsAttentionChloridesGastroenterology and hepatologyHospital medicineHydrochloric acidPhosphates ePublished: 1 December 2008 Issue Published: 1 November 1938 PDF downloadLoading ...