THE USE OF L-ARTERENOL IN A CASE OF HYPERSENSITIVITY TO TETANUS ANTITOXIN
Authors: R C GUMPEL, J J KRISTAN, P LIPTON
Journal: Annals of Internal Medicine (1956)

Case Reports1 February 1956THE USE OF L-ARTERENOL IN A CASE OF HYPERSENSITIVITY TO TETANUS ANTITOXINROY C. GUMPEL, M.D., JOSEPH J. KRISTAN, M.D., PHILIP LIPTON, M.D.ROY C. GUMPEL, M.D.Search for more papers by this author, JOSEPH J. KRISTAN, M.D.Search for more papers by this author, PHILIP LIPTON, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-2-406 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis is a report of an untoward reaction to horse serum (tetanus antitoxin) and its successful treatment with 1-arterenol. Tuft1 estimated that death from atopic reaction results once in 70,000 persons receiving injections of tetanus antitoxin. If reported incidence is a reliable index, clinical sensitivity to horse serum is comparatively rare. However, as with other unfortunate therapeutic reactions, the actual occurrence is greater than that reported.Based on Feinberg's2classification of allergy to injected substances, we feel our patient's response was that of an immediate serum reaction. The patient gave a history of having previously received a sensitizing injection of...Bibliography1. Tuft L: Clinical allergy, 1st Ed., 1937, W. B. Saunders Company, Philadelphia. Google Scholar2. Feinberg SM: Allergy in practice, 2nd Ed., 1946, Year Book Publishers, Chicago. p. 344. Google Scholar3. VonEuler US: Hormones of the sympathetic nervous system and the adrenal medulla, Brit. M. J. 2: 105, 1951. CrossrefGoogle Scholar4. GoldenbergFaberAlstonChargaff MMEJEC: Evidence for the occurrence of nor-epinephrine in the adrenal medulla, Science 109: 534, 1949. CrossrefMedlineGoogle Scholar5. KurlandMalach GSM: The clinical use of nor-epinephrine in the treatment of shock accompanying myocardial infarction and other conditions, New England J. Med. 247: 383, 1952. CrossrefMedlineGoogle Scholar6. KurlandFreedberg GSAS: Potentiating effects of ACTH and cortisone on pressor response to intravenous infusion of L-nor-epinephrine, Proc. Soc. Exper. Biol. and Med. 78: 28, 1951. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication November 26, 1954.From the Medical Service, Veterans Administration Hospital, Newington, Connecticut.Reviewed in the Veterans Administration and published with the approval of the Chief Medical Director. The statements and conclusions published by the authors are a result of their own study and do not necessarily reflect the opinion or policy of the Veterans Administration. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1956Volume 44, Issue 2Page: 406-410KeywordsAdrenocorticotropic hormoneAllergy and immunologyAntitoxinsAttentionHypersensitivityHypertensionMedical servicesTetanus ePublished: 1 December 2008 Issue Published: 1 February 1956 PDF downloadLoading ...