THE ETIOLOGY AND MANAGEMENT OF THE HEMORRHAGIC DIATHESES
Authors: C A DOAN
Journal: Annals of Internal Medicine (1949)

Article1 December 1949THE ETIOLOGY AND MANAGEMENT OF THE HEMORRHAGIC DIATHESESCHARLES A. DOAN, M.D., F.A.C.P.CHARLES A. DOAN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-31-6-967 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptHemorrhage uncontrollable except by expert medical management, may present in the practice of any physician at any time. Under normal conditions, the integrity of the vascular system and the circulating fluidity of the blood reflect a nice physiologic balance in an exceedingly sensitive and complicated coagulation mechanism. The physical-chemical intricacies of normal blood coagulation continue to challenge the best thought of many investigators and to stimulate ever more detailed experimentation in many laboratories, in the attempt to better understand and to more effectively solve the clinical problems centering about abnormal hemorrhage. The concepts and terminology arising from parallel efforts in...Bibliography ALLEN JG: Abnormal bleeding, Jr. Am. Med. Assoc., 1949, cxxxlx, 1251. CrossrefGoogle Scholar BRINKHOUS KM: Clotting defect in hemophilia: deficiency in a plasma factor required for platelet utilization, Proc. Soc. Exper. Biol., and Med., 1947, lxvi, 117. CrossrefGoogle Scholar CONLEYHARTMANNMORSE CLRCWI: Clotting behavior of human plateletfree plasma: evidence for the existence of a "plasma thromboplastin," Jr. Clin. Invest., 1949, xxviii, 340. CrossrefGoogle Scholar DAVIDSONEPSTEINMILLERTAYLOR CSRDGFFH: Hemophilia: a clinical study of forty patients, Blood, 1949, iv, 97. CrossrefGoogle Scholar MACFARLANEBIGGS RGR: Fibrinolysis: its mechanism and significance, Blood, 1948, iii, 1167. CrossrefGoogle Scholar OWREN PA: Coagulation of blood: investigations on a new clotting factor, Acta med. Scandinav., (Suppl. 194), 1947, cxxviii, 1-327. Google Scholar QUICK AJ: Components of the prothrombin complex, Am. Jr. Physiol, 1947, cli, 63. CrossrefGoogle Scholar QUICKRENESTEFANINI AJHCM: The value and the limitations of the coagulation time in the study of the hemorrhagic diseases, Blood, 1948, iii, 1120. CrossrefGoogle Scholar QUICKSHANHERGESTEFANINI AJJNM: The rôle of platelets in the coagulation of the blood, Am. Jr. Med. Sci., 1949, ccxvii, 198. CrossrefGoogle Scholar WAREMURPHYSEEGERS AGRCWH: The function of Ac-globulin in blood clotting, Science, 1947, cvi, 618. CrossrefGoogle Scholar WARESEEGERS AGWH: Serum Ac-globulin: formation from plasma Ac-globulin: rôle in blood coagulation; partial purification; properties; and quantitative determination, Am. Jr. Physiol., 1948, clii, 567. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Columbus, Ohio*Presented as a Morning Lecture at the Twenty-Ninth Annual Session of the American College of Physicians, San Francisco, California, April 21, 1948. Received for publication September 8, 1949. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPurpura, Pigmentation and Yellow Nails of the Lower Extremities in DiabeticsBIBLIOGRAPHYIrregular Blood CoagulationChristmas diseaseFibrinogenmangel-KrankheitenTHE USE OF ACTH AND CORTISONE IN IDIOPATHIC THROMBOCYTOPENIC PURPURA AND IDIOPATHIC ACQUIRED HEMOLYTIC ANEMIA*MURIEL C. MEYERS, STANLEY MILLER, JAMES W. LINMAN, FRANK H. BETHELL, F.A.C.P.Panhematopenia and Hypersplenia.(Observations with Reference to a Case Report.)A Study of the Thrombopoiesis in Various Thrombopenic States1A Study of the Thrombopoiesis in Various Thrombopenic States1Splenomegaly with Hypersplenism Due to Sarcoidosis 1 December 1949Volume 31, Issue 6Page: 967-988KeywordsBloodBlood coagulationEtiologyHemorrhage ePublished: 1 December 2008 Issue Published: 1 December 1949 Copyright & PermissionsCopyright, 1949, by The American College of PhysiciansPDF downloadLoading ...