tbuckley/cabot-search huggingface dataset:
Eyes wide open: MOSE Performance in EUS FNB
Authors: A. C. Bravo, C. Nascimento, B. Morão, J. Revés, B. Abreu, A. Bargas, R. Loureiro, L. Glória, C. Fidalgo
Journal: Endoscopy (2024)

Aims Endoscopic ultrasound fine needle biopsy (EUS-FNB) is the preferred method for sampling solid lesions in the digestive wall or adjacent organs. Strategies to enhance its efficacy have been explored, with recent studies indicating that Macroscopic On-Site Evaluation (MOSE) by an echoendoscopist can be comparable to Rapid On-site Evaluation (ROSE) by an anatomopathologist. This study aims to assess the performance of MOSE in EUS-FNB, specifically using the 22G Franseen needle.
Automatic Three-Dimensional Reconstruction of the Esophagus in Achalasia Patients undergoing POEM: a Comprehensive Assessment of Treatment Outcomes and pathophysiological Changes
Authors: S. Nagl, V. Grünherz, M. Elia, F. Stieler, T. Peter, B. Bauer, A. Muzalyova, H. Messmann, A. Ebigbo
Journal: Endoscopy (2024)

Aims Achalasia is a chronic esophageal motility disorder. Peroral endoscopic myotomy (POEM) is a standard treatment option for patients with achalasia. However, treatment response varies due to factors such as achalasia type, degree of dilatation, pressure, and distensibility indices. This study presents an innovative approach for risk stratification, treatment response prediction and pathophysiological understanding based on an automatic three-dimensional (3-D) reconstruction of the tubular esophagus (TE) and the lower esophageal sphincter (LES) in patients undergoing POEM for achalasia.
Endoscopic radiofrequency ablation versus hybrid argon plasma coagulation in the treatment of Barrett&amp;apos;s esophagus – the patients&amp;apos; perspective: a randomized controlled trial assessing procedural acceptability and safety (the RATE study)
Authors: W. Januszewicz, D. P. Nastazja, E. Wrońska, R. Klimkowski, M. Wojtowicz-Popiel, J. Regula, M. F. Kaminski
Journal: Endoscopy (2024)

Aims Endoscopic radiofrequency ablation (RFA) and argon plasma coagulation (APC) are established ablation techniques in the treatment of Barrett's esophagus (BE). Currently, a modification of the APC method involving submucosal injection of saline preceding the thermal ablation (hybrid-APC) has become available. Both RFA and h-APC are highly effective in eradicating BE, but data comparing the patient-related outcomes of these procedures remain limited. We aimed to evaluate the acceptability, safety, and impact on the patient's quality of life of these two methods.
Endoscopic retrograde cholangiopancreatography training using a silicone simulator fabricated using a 3D printing technique
Authors: C. I. Kwon, S. P. Shin, K. J. Lee, M. J. Sung, J. C. Kim, G. B. Kim, M. Y. Kim, S. Y. Han, S. I. Jang, M. Takenaka
Journal: Endoscopy (2024)

Aims Endoscopic retrograde cholangiopancreatography (ERCP) training remains challenging; no suitable training model properly simulates the anatomical and realistic features encountered during the procedure. This study used 3D printing techniques to develop and optimize a portable ERCP training simulator and to implement basic and advanced practical techniques. Subsequently, we aimed to determine whether endoscopy trainees acquired proficiency in ERCP techniques and assess any improvements in their skill levels from using this model.
Efficacy of Remimazolam with Fentanyl versus Midazolam with Fentanyl for sedation in screening colonoscopy: A randomized controlled study
Authors: A. Armbrecht, M. D. Rasmussen, A. M. Moeller, P. Vilmann
Journal: Endoscopy (2024)

Aims There is a need to improve moderate sedation for colonoscopy while maintaining safety. Remimazolam is an ultrashort-acting benzodiazepine with a favorable safety profile that might reduce recovery time and hence prove beneficial in a large clinical setting.
Impact of a structured capsule endoscopy training program on capsule endoscopy proficiency: a 3-year prospective Portuguese study
Authors: T. Lima Capela, J. Goncalves, A. I. Ferreira, V. Macedo Silva, C. Macedo, C. Arieira, S. Xavier, T. Gonçalves, P. Boal Carvalho, F. Dias De Castro, J. Magalhães, B. Rosa, M. J. Moreira, J. Cotter
Journal: Endoscopy (2024)

Aims There is scarce evidence regarding the outcomes of capsule endoscopy (CE) training programs and its impact amongst trainees. We aimed to analyze the impact of a CE training program on CE proficiency with a new developed CE training assessment tool, the pre and post Capsule Endoscopy Training Assessment (CETA). Additionally, we investigated whether prior experience in flexible endoscopic techniques or CE could influence participants' CETA mean score and achievement of a posttraining learning goal.
EUS for Diagnosis of Ampullary Cancer in a Patient with Lynch Syndrome
Authors: H.H. W. Liu, T. Cheung, Y. Hui
Journal: Endoscopy (2024)

Aims Lynch syndrome is the most common cause of hereditary colorectal cancers and accounts for 1-3% of all colon cancers [1]. Apart from the large bowel, patients are also at risk of extra-colonic tumours. In particular, they have a 2% lifetime hazard of biliary tract cancers [2]. Nevertheless, there is limited data in the literature concerning ampullary carcinoma associated with Lynch syndrome. We report a case of MSH2-deficient cancer of ampulla of Vater, and the pivotal role of EUS in the diagnostic process.
Helicobacter pylori – uninfected early gastric cancer: proposal for a new histological classification and clinicopathological and endoscopic features
Authors: U. Ryota, U. Hiroya, Y. Takashi, N. Akihito
Journal: Endoscopy (2024)

Aims In recent years, the frequency of Helicobacter-pylori (Hp) – uninfected gastric cancer (HPUGC) is expected to increase relatively with the spread of Hp eradication in Asian countries. However, HPUGC is thought to be more difficult to detect and diagnose endoscopically rather than Hp-associated gastric cancer. Therefore, we aimed to establish a new endoscopic diagnostic system of HPUGC and elucidate the clinicopathological and endoscopic features of HPUGC.
Establishing Preconditions for Effective Duodenoscope Reprocessing: An Observational Cohort Study
Authors: K. van der Ploeg, M. C. Vos, N. S. Erler, B.C.G. C. Mason-Slingerland, J. A. Severin, M. J. Bruno
Journal: Endoscopy (2024)

Aims The use of contaminated duodenoscopes in endoscopic retrograde cholangiopancreatography (ERCP) has caused numerous healthcare-associated infection outbreaks [1]. Despite adherence to reprocessing protocols, duodenoscopes often remain contaminated [2]. Moreover, there's a lack of evidence outlining the prerequisites for adequate duodenoscope cleaning, disinfection, and storage to prevent contamination. This study aims to investigate the effect of manual cleaning and drying factors on duodenoscope contamination.
Do prophylactically placed pancreatic stents need to be removed – a retrospective chart review
Authors: A. Feiden, F. Rybinski, S. Kahl, M. Zimmerli, H. Heinrich
Journal: Endoscopy (2024)

Aims Prophylactic pancreatic stenting (PPS) is recommended by guidelines to reduce the risk of post ERCP pancreatitis after accidental pancreatic canulation during ERC. There is no clear guidance and evidence on the optimal time frame and if PPS need be removed at all after ERCP. While some centers do not actively remove PPS, some recommend removal after 5-14 days.
Additional value of expert care for patients with ultra-long Barrett’s Esophagus in the Netherlands: results of the nationwide Barrett Expert Center Registry
Authors: E.P. D. Verheij, M. Houben, S. N. Van Munster, B.L.A. M. Weusten, L. Alvarez Herrero, A. Alkhalaf, E. J. Schoon, W. Curvers, A. D. Koch, M.C. W. Spaander, P. Zellenrath, W. B. Nagengast, J. Westerhof, M.H.M. G. Houben, S. L. Meijer, J. Bergman, R. Pouw
Journal: Endoscopy (2024)

Aims The neoplastic progression risk in Barrett's Esophagus (BE) increases with increasing BE length. Therefore, some guidelines recommend that patients with ultra long-segment BE≥10cm (ULS-BE) are referred to an expert center, however, recommendations on further management are lacking. This study aimed to evaluate findings of an imaging endoscopy performed at a Barrett Expert Center (BEC), for patients with ULS-BE.
Prognosis of low-risk pT1 CRC locally resected en bloc and in piecemeal – Comparative study with two international cohorts: Epit1 Consortium and Dutch T1 group
Authors: M. Daca-Alvarez, K. Gijsbers, D. Zaffalon, K. Saez De Gordoa, M. Lacle, M. Cuatrecasas, L.M. G. Moons, M. Pellisé
Journal: Endoscopy (2024)

Aims To compare en bloc and piecemeal resected low-risk pT1CRC in terms of overall survival (OS) and metastasis free survival (MFS).
Usefulness of endoscopic hand suturing for bleeding prevention following gastric endoscopic submucosal dissection: a multicenter phase II study
Authors: H. Takayama, Y. Morita, O. Goto, K. Hirasawa, C. Sato, T. Oyama, A. Takahashi, S. Abe, Y. Saito, H. Ono, N. Kawada, T. Otsuka, K. Iwakiri
Journal: Endoscopy (2024)

Aims Postoperative bleeding accounts for approximately 5% in gastric endoscopic submucosal dissection (ESD) and sometimes leads to a fatal condition. Particularly, patients with continuous administration of antithrombotic agents (ATAs) have a high risk of bleeding. We developed endoscopic hand suturing (EHS), which provides a reliable closure of the mucosal defect following ESD by continuous intraluminal suturing of the tissue using a dedicated flexible needle holder and a commercially available absorbable barbed suture. In this multicenter phase II study, we investigated the effectiveness of EHS for bleeding prevention following gastric ESD in patients at a high risk of delayed bleeding.
EUS-guided gastroenterostomy versus enteral stenting for malignant gastric outlet obstruction: a propensity score-matched study
Authors: M. C. Conti Bellocchi, E. Gasparini, S. Stigliano, L. Bernardoni, A. Gabbrielli, F. M. Di Matteo, S. F. Crinò
Journal: Endoscopy (2024)

Aims Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is a minimally invasive option of treatment for malignant gastric outlet obstruction (mGOO), emerging as alternative to enteral stenting (ES) and surgery. We aimed to compare the stent dysfunction rate, patency, and clinical outcome of EUS-GE with a propensity matched cohort of ES.
Treatment procedures for intractable gastroesophageal reflux disease after peroral myotomy for achalasia: anti-reflux ablation, mucosectomy, Stretta radiofrequency
Authors: A. Y. Lee, J. Y. Seo, J. Y. Cho, S. H. Kim
Journal: Endoscopy (2024)

Aims Treating intractable gastroesophageal reflux disease (GERD) after peroral endoscopic myotomy (POEM) is challenging owing to paradoxical treatment scenarios. No study has compared the safety and efficacy of anti-reflux ablation therapy (ARAT), anti-reflux mucosectomy (ARMS), and Stretta radiofrequency (SRF) for intractable GERD after POEM. We compared these therapeutic methods for iatrogenic intractable GERD after POEM.
Efficacy and safety of underwater ESD with water pressure method for colorectal neoplasm: a propensity score matching
Authors: K. Kirita
Journal: Endoscopy (2024)

Aims Endoscopic submucosal dissection (ESD) for colorectal neoplasm has been widely accepted treatment, but it has been difficult technically not yet, and so various methods and devices have been reported. Therefore, we introduced underwater ESD with water pressure method (U-ESD) from 2020. We evaluated the efficacy and safety of treatment for colorectal neoplasm by U-ESD compared with conventional ESD (C-ESD).
The Effectiveness of Using an Interactive Video in Consenting Process versus the Standard Process in Increasing the Awareness of Patients Undergoing Endoscopy Procedures: A Real-Life Cross-Sectional Survey Study
Authors: E. Aljahdli, G. Malibari, B. Alasmari
Journal: Endoscopy (2024)

Aims the objective of this study was to compare the effectiveness of including a video recording to the standard informed consent in increasing the patients' comprehension and satisfaction
Hybrid Argon Plasma Coagulation in the Treatment of Barrett&amp;apos;s Esophagus: a Meta-analysis and Systematic Review
Authors: R. Maselli, D. Massimi, M. Menini, M. Spadaccini, A. Capogreco, A. Fugazza, S. Carrara, A. Facciorusso, T. Rizkala, A. Schilirò, D. Ramai, M. Knabe, M. Sharma, C. Hassan, A. Repici
Journal: Endoscopy (2024)

Aims Radiofrequency ablation is a widely used technique for ablating flat dysplastic Barrett esophagus. Hybrid-APC (H-APC) is an emerging technique, which combines argon plasma coagulation with saline injection prior to ablation therapy to minimize damage to the muscular layers. Our goal was to conduct a systematic review of existing literature to assess the safety and efficacy of H-APC.
Meta-analysis of diagnostic performance of fluorescence in situ hybridization (FISH) for biliary strictures
Authors: M. Aggarwal, D. Simadibrata, B. Petersen, J. Martin, E. Barr-Fritcher, A. Schneider, B. Kipp, L. Roberts, G. Gores, V. Chandrasekhara
Journal: Endoscopy (2024)

Aims Standard brush cytology has poor sensitivity for detecting malignancy in biliary strictures. Fluorescence in situ hybridization (FISH) has been reported as a useful adjunctive test in evaluation of biliary strictures. However, the diagnostic performance and definitions of a positive FISH result vary across different studies. This meta-analysis aimed to define the diagnostic performance of FISH in evaluation of biliary strictures.
Clearing the Way: Impact of a combined low volume polyethylene glycol lavage with low residue diet and preprocedure simethicone on bowel cleansing quality – a randomised controlled trial
Authors: S. Harindranath, M. Irtaza, G. Jain, S. Sundaram, A. Vaidya, B. R. Patra, A. Shukla
Journal: Endoscopy (2024)

Aims The quality of bowel cleansing is known to influence the quality of colonoscopy. A case has been made for dietary modification in the form of low residue diet (LRD) along with polyethylene glycol (PEG) preparation resulting in better bowel cleansing. Also, combined use of simethicone and PEG as lavage solution for bowel preparation has been shown to reduce abdominal pain, bloating and discomfort. We aimed to assess the safety and efficacy of a combined bowel preparation with low volume PEG, low residue diet and simethicone and compare it to the traditional PEG based bowel preparation regimens.
Analysis of intragastric meal distribution during preoperative gastric emptying scintigraphy can predict long-term clinical response in patients with gastroparesis treated with gastric per oral endoscopic myotomy
Authors: A. Debourdeau, V. Vitton, G. Sandra, M. Barthet, J. M. Gonzalez
Journal: Endoscopy (2024)

Aims Gastric emptying scintigraphy (GES) is the gold standard for the diagnosis of gastroparesis. However, data are lacking regarding the prognostic value of pre-operative intragastric meal distribution during GES, in patients undergoing gastric peroral endoscopic myotomy (GPOEM) for gastroparesis. This study investigated the association of GES morphologic parameters and the long-term clinical success of G-POEM.
Endoscopic submucosal dissection for superficial neoplastic lesions involving ileocecal valve: a Western multicenter study
Authors: F. Barbaro, M. F. Chiappetta, P. Cecinato, F. Pugliese, F. Azzolini, S. Sferrazza, G. Fiori, T. Schepis, R. Maselli, C. Spada
Journal: Endoscopy (2024)

Aims The clinical outcomes of endoscopic submucosal dissection (ESD) for lesions involving ileocecal valve (ICV) remain unclear in Western setting. This study aimed to evaluate the efficacy and safety of ESD in the treatment of lesions involving ICV compared to other right-side colon lesions.
Freehand precut- A savior for difficult ERCP- Retrospective analysis of 3000 ERCPs at tertiary care center in India
Authors: P. Chintan, P. N. Desai, K. Mayank, M. Rajiv, S. Nandwani, P. Ritesh, N. Patel, M. Sethia, R. Kakadiya
Journal: Endoscopy (2024)

Aims To analyze the efficacy of freehand precut for selective cannulation in difficult ERCP and its role in improving technical success rate, obviating need for EUS guided/other rendezvous techniques
Combined Single Session EUS and ERCP Procedures; The Challenges of Conscious Sedation
Authors: E. Keating, G. Bennett, J. R. Campion, S. Mcguinness, H. Martir, B. Kelleher, S. Stewart, N. Ramlaul, J. Leyden
Journal: Endoscopy (2024)

Aims Completing advanced endoscopic procedures e.g. EUS and ERCP, in a single session, under conscious sedation (benzodiazepines±opiates) is challenging. International recommendations favour enhanced sedation (e.g. propofol) for EUS and ERCP to optimise outcomes. Non-anaesthesiologist administration of propofol (NAAP) is restricted by regulatory and anaesthetic constraints in Irish endoscopy. Access to anaesthetist delivered propofol sedation (PropERCP) is limited to a minority of procedures. [1]
Intestinal preparation for small bowel capsule endoscopy: polyethylene glycol alone or polyethylene glycol with ascorbic acid?
Authors: A. I. Ferreira, J. Goncalves, T. Lima Capela, S. Xavier, C. Arieira, B. Rosa, J. Cotter
Journal: Endoscopy (2024)

Aims Compare the rate of complete examinations, quality of bowel preparation, diagnostic yield, small bowel transit time and tolerability, in small bowel capsule endoscopy (SBCE), using 2 different protocols for intestinal preparation.
Impact of inappropriate indication to colonoscopy on waste production and potential benefit of an intervention. A multicenter prospective study
Authors: L. Frazzoni, F. Cortellini, G. Gibiino, M. Di Marco, C. Fabbri, H. Bertani, R. Conigliaro, L. Laterza, A. Mussetto, P. Cecinato, P. Fusaroli, G. Aragona, C. Hassan, G. Antonelli, M. Dinis-Ribeiro, L. Fuccio
Journal: Endoscopy (2024)

Aims Colonoscopy leads to production of an important amount of carbon dioxide (CO2) quantified in 6.71 Kg CO2e (direct emissions) and as high as 28 kg CO2e (direct and indirect emissions). Aim of the present study was to quantify the impact of inappropriate indication to colonoscopy on waste production and the potential benefit of an intervention.
Image quality pitfalls in AI: Safeguarding Barrett&amp;apos;s neoplasia detection with robust deep learning training strategies
Authors: M. Jong, T. Jaspers, C. Kusters, J. Jukema, K. Fockens, R. van Eijck van Heslinga, T. Boers, F. Van Der Sommen, P. De With, J. De Groof, J. Bergman
Journal: Endoscopy (2024)

Aims Endoscopic artificial intelligence systems, developed in expert centers with high-quality imaging, may underperform in community hospitals due to image quality heterogeneity. This study aimed to quantify the performance degradation of a CADe system for Barrett's neoplasia, when exposed to the heterogeneous imaging conditions of community hospitals. Subsequently, different state-of-the-art training strategies were evaluated to mitigate this performance loss.
Comparative diagnostic performance of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) versus endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) for tissue sampling of solid pancreatic and non-pancreatic lesions without ROSE: a prospec
Authors: M. akram, M. akram
Journal: Endoscopy (2024)

Aims Endoscopic ultrasound-guided tissue acquisition, including both fine needle aspiration (EUS-FNA) and fine needle biopsy (EUS-FNB), has been widely performed to obtain samples from pancreatic and non-pancreatic lesions. The impact of the diagnostic yield between FNA and FNB remains unclear. We conducted this study to compare the diagnostic performance and accuracy of the 22-gauge FNA needles with the 22-gauge FNB needles in sampling solid pancreatic and non-pancreatic lesions.
A basal-like pancreatic cancer molecular subtype can be identified on EUS-acquired tissue and is associated to current smoking, lower Ca19.9 expression and worse prognosis
Authors: L. Archibugi, R. Ponz de Leon Pisani, P. Lazzano, M. Tacelli, P. Zaccari, M. C. Petrone, G. Rossi, L. Apadula, G. Vanella, C. Sette, C. Doglioni, M. Falconi, M. Reni, P. Arcidiacono, G. Capurso
Journal: Endoscopy (2024)

Aims Two pancreatic cancer(PDAC) transcriptome subtypes have been defined (basal-like and classical) that seem related to different prognosis. Nevertheless, RNA-extraction from pancreatic tissue is cumbersome and has been performed mainly on surgical samples, representative of<20% of cases. Most PDAC patients undergo Endoscopic-UltraSound(EUS)-guided tissue acquisition(EUS-TA), but RNA-sequencing on such samples has been rarely performed or limited to paraffin-embedded samples with low RNA quality. Furthermore, the association between molecular subtype and patient-related factors such as BMI, smoking, drug use, tumor location and Ca19.9 expression is uninvestigated. Our aim was to correlate PDAC molecular subtypes identified by RNA-sequencing on EUS-TA samples with prognosis and evaluate whether they are associated to patients' factors.
Predictors of endoscopic cure for Malignant Colorectal Polyps
Authors: J. Goncalves, A. I. Ferreira, M. Souto, S. Xavier, P. Boal Carvalho, J. Magalhães, J. Cotter
Journal: Endoscopy (2024)

Aims Malignant colorectal polyps present a unique challenge due to their potential for metastasis. While complete endoscopic resection often achieves cure, comprehensive data on the characteristics influencing it remain limited. This study aimed to elucidate the key predictors associated with achieving endoscopic cure for malignant polyps.
Comparison of ciprofol versus propofol for sedation of adults undergoing gastrointestinal endoscopic procedures: a systematic review and meta-analysis
Authors: P. Bertoldi, J. Aguirre, E. Barbosa
Journal: Endoscopy (2024)

Aims This systematic review and meta-analysis aimed to compare the efficacy, safety, and patient satisfaction between ciprofol, a novel sedative agent, and propofol for sedation of adults undergoing gastrointestinal (GI) endoscopy [1] [2] [3] [4] [5] [6].
Off-label use of lumen apposing metal stents for treatment of short benign biliary strictures: a single tertiary center experience
Authors: M. Capasso, G. Bonato, L. Dioscoridi, E. Forti, F. Pugliese, M. Cintolo, M. Bravo, A. Palermo, F. Fimiano, M. Mutignani
Journal: Endoscopy (2024)

Aims Endoscopic stenting is considered the mainstay of biliary treatment for benign biliary strictures; temporary insertion of multiple plastic stents or of a fully covered self-expandable metal stent (FC-SEMS) are the preferred methods due to their favorable results. However, there is a not-negligible rate of stricture recurrence and spontaneous stent migration, the latter being a leading cause of treatment failure. Lumen-apposing metal stents (LAMS), developed for transluminal drainages, have a unique design with short length, large diameter and wide flanges which make them less prone to migration. LAMS have recently been proposed as a novel modality for treating short benign gastrointestinal strictures. Aim of our study was to describe the intraluminal use of LAMS to treat short benign biliary strictures.
Successful management of biliary obstruction secondary to a hilar stricture using EUS-guided hepaticogastrostomy
Authors: M. Lajin, N. Khan
Journal: Endoscopy (2024)

Abstract Text An 83-year-old female presented with obstructive jaundice. MRI of the abdomen showed dilated intrahepatic ducts due to a hilar stricture without a mass. CA 19-9 was elevated. ERCP failed to cannulate the bile duct. EUS showed dilated intrahepatics without a mass. A dilated left intrahepatic duct was punctured with a 19 gauge needle, a cholangiogram was obtained, and a wire was coiled inside that duct. The hepaticogastrostomy track was then dilated using a 6 mm balloon at multiple stations. Finally, a fully covered metal stent of 8mm x 10cm was deployed. Her bilirubin normalized over the following six weeks. The patient and family decided to pursue conservative management. As a result, the suspected diagnosis of cholangiocarcinoma was not confirmed.