tbuckley/cabot-search huggingface dataset:
Letter to the Editor: a commentary on ‘safety and efficacy of enhanced recovery after surgery among patients undergoing percutaneous nephrolithotomy : a systematic review and meta-analysis’
Authors: Yiqi Huang, Weigang Shen, Meixiang Han, Langping Ling
Journal: International Journal of Surgery (2024)

aDepartment of Nephrology, Shaoxing Second Hospital, Shaoxing, Zhejiang, 312000, China bDepartment of Emergency Internal Medicine, Shaoxing Second Hospital, Shaoxing, Zhejiang, 312000, China Yiqi Huang, Weigang Shen and Meixiang Han: These authors have contributed equally to this work. Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: Department of Emergency Internal Medicine, Shaoxing Second Hospital, Shaoxing, Zhejiang, 312000, China. E-mail address: [email protected] (L. Ling). This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0/
Perioperative management of sarcopenia in patients undergoing major surgeries in Singapore: a modified delphi consensus
Authors: Frederick H Koh, Lincoln MY Chew, Nicky Wong, Alfred WC Kow, Dominic Yap, Sherryl Ng, Jingyu Ng, Ming-Yuan Tan, Daniel JK Lee, Angie PS Au-Yong, Clement CK Yan, Priscilla Darmawirya, Balachandran Jayachandran, Andrea Maier, Hazel EL Yeong, Samuel TH Chew, Fung-Joon Foo, Kwang-Yeong How, Doris HL Ng
Journal: International Journal of Surgery (2024)

Ageing population is a worldwide phenomenon with correspondingly higher proportion of older patients being treated in the hospital setting. Sarcopenia, which increases with age, has serious negative implications on health, hospitalisation, and overall postoperative recovery. There is no mutual consensus on perioperative management of sarcopenia in surgical patients in Singapore. The purpose of this study is to create greater clarity pertaining to the recognition of sarcopenia, the application of assessment criteria of sarcopenia and perioperative management of surgical patients in Singapore.
A review: targeting UBR5 domains to mediate emerging roles and mechanisms: chance or necessity?
Authors: Yizhu Wang, Kaiyi Niu, Yanlong Shi, Feilong Zhou, Xinhao Li, Yunxin Li, Tianyi Chen, Yewei Zhang
Journal: International Journal of Surgery (2024)

Ubiquitinases are known to catalyze ubiquitin chains on target proteins to regulate various physiological functions like cell proliferation, autophagy, apoptosis, and cell cycle progression. As a member of E3 ligase, ubiquitin protein ligase E3 component n-recognin 5 (UBR5) belongs to the HECT E3 ligase and has been reported to be correlated with various pathophysiological processes. In this review, the authors give a comprehensive insight into the structure and function of UBR5. The authors discuss the specific domains of UBR5 and explore their biological functions separately. Furthermore, the authors describe the involvement of UBR5 in different pathophysiological conditions, including immune response, virus infection, DNA damage response, and protein quality control. Moreover, the authors provide a thorough summary of the important roles and regulatory mechanisms of UBR5 in cancers and other diseases. On the whole, investigating the domains and functions of UBR5, elucidating the underlying mechanisms of UBR5 with various substrates in detail may provide new theoretical basis for the treatment of diseases, including cancers, which could improve future studies to construct novel UBR5-targeted therapy strategies.
A commentary on ‘The efficacy and safety of hydrotherapy in patients with knee osteoarthritis: a meta-analysis of randomized controlled trials’
Authors: Minghao Tong, Kang Liu
Journal: International Journal of Surgery (2024)

aThe Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China bDepartment of Osteology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: Second Affiliated Hospital, Zhejiang Chinese Medical University Address:No.318 Chaowang Road, Gongshu District, Hangzhou, Zhejiang Province. E-mail address: [email protected] (K. Liu). This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/
A commentary on “the anterior neck scar outcomes of conventional thyroidectomy using a wound protector: a multicenter double-blinded randomized controlled trial”
Authors: Wanyi Zhang, Haiyan Pan, Gang Li
Journal: International Journal of Surgery (2024)

Department of Emergency Medicine, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, People's Republic of China Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: Department of Emergency Medicine, The Third Affiliated Hospital of Zhejiang Chinese Medical University, 219 Moganshan Road, Hangzhou, 310000, People's Republic of China. Tel.:+86 0571-88393542; fax:+0571-88393542. E-mail address: [email protected] (G. Li). This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/
A commentary on “a multicenter case–controlled study on laparoscopic hepatectomy versus microwave ablation as first-line therapy for 3–5 cm hepatocellular carcinoma in patients aged 60 and older”
Authors: Hanke Ye, Meiyin Zhou, Qingjing Ru
Journal: International Journal of Surgery (2024)

aThe Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People's Republic of China bThe Third Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, People's Republic of China cDepartment of Infectious disease, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang,People's Republic of China Hanke Ye and Meiyin Zhou contributed equally to this work and share first authorship. Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: The Second Affiliated Hospital of Zhejiang Chinese Medical University, 318 Chaowang Road, Gongshu District, Hangzhou, Zhejiang 310005, People's Republic of China. E-mail address: [email protected] (Q. Ru). This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/
A commentary on the article entitled ‘progress in the surgical treatment of sacrococcygeal pilonidal sinus’
Authors: Chu-Yun Xing, Ming-Yan Huang, Shi-Zhou Cheng
Journal: International Journal of Surgery (2024)

aDepartment of Pain Management, The First Affiliated Hospital of Yangtze University Jingzhou of Hubei Province,434000,China bDepartment of Ophthalmology, The First Affiliated Hospital of Yangtze University, Jingzhou of Hubei Province,434000,China Authors' note: This work has not yet been presented elsewhere. Data sharing is not applicable to this article as no new data were created or analyzed in this study. Chu-Yun Xing and Ming-Yan Huang: Contributed equally. Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: Department of Ophthalmology, The First Affiliated Hospital of Yangtze University, Jingzhou of Hubei Province,434000,China. E-mail address: [email protected] (S-Z. Cheng). This is an open access article distributed under the Creative Commons Attribution-ShareAlike License 4.0, which allows others to remix, tweak, and build upon the work, even for commercial purposes, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-sa/4.0/
Cognitive vision- AI automation of the surgical eye in fluorescence angiography. Correspondence
Authors: Ronan A. Cahill
Journal: International Journal of Surgery (2024)

aUCD Centre for Precision Surgery, University College Dublin, Dublin, Ireland bDepartment of Surgery, Mater Misericordiae University Hospital, Dublin, Ireland Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article Published online ■ ■ *Corresponding author. Address: UCD Centre for Precision Surgery, 47 Eccles Street, Dublin 7, Ireland. Tel: +353 (1) 7164597. E-mail address: [email protected] (R. Cahill). This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/
Advances in preclinical surgical therapy of cardiovascular diseases
Authors: Peiyuan Li, Yuan Chang, Jiangping Song
Journal: International Journal of Surgery (2024)

Cardiovascular disease is the most common cause of death worldwide, resulting in millions of deaths annually. Currently, there are still some deficiencies in the treatment of cardiovascular diseases. Innovative surgical treatments are currently being developed and tested in response to this situation. Large animal models, which are similar to humans in terms of anatomy, physiology, and genetics, play a crucial role in connecting basic research and clinical applications. This article reviews recent preclinical studies and the latest clinical advancements in cardiovascular disease based on large animal models, with a focus on targeted delivery, neural regulation, cardiac remodeling, and hemodynamic regulation. It provides new perspectives and ideas for clinical translation and offers new methods for clinical treatment.
A commentary on“ Silent gallbladder stone in kidney transplantation recipients: should it be treated? a retrospective cohort study”
Authors: Fangxiao Xia, Chao Su
Journal: International Journal of Surgery (2024)

aDepartment of Nephrology, Ganzhou Hospital of Guangdong Provincial People's Hospital, Ganzhou Municipal Hospital, Ganzhou, China bDiscipline of Physiology, School of Medicine, University of Galway, Ireland Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article Published online ■ ■ *Corresponding Author: Discipline of Physiology, School of Medicine, University of Galway, Ireland, Email: [email protected] (C. Su). This is an open access article distributed under the Creative Commons Attribution-ShareAlike License 4.0, which allows others to remix, tweak, and build upon the work, even for commercial purposes, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-sa/4.0/
Letter to the editor: Rethinking the preoperative risk assessment classifier for PTC: A Surgeon’s view from China
Authors: Yang Shi, Wenwu Dong, Ping Zhang
Journal: International Journal of Surgery (2024)

Department of Thyroid Surgery, The First Hospital of China Medical University, Shenyang, P.R. China Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: Department of Thyroid Surgery, The First Hospital of China Medical University, 155 Nanjing Bei Street, Shenyang, Liaoning, China. E-mail address: [email protected] (W. Dong). *Corresponding author. Address: Department of Thyroid Surgery, The First Hospital of China Medical University, 155 Nanjing Bei Street, Shenyang, Liaoning, China. E-mail address: [email protected] (P. Zhang). This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/
Radiomics-based machine learning approach for the prediction of grade and stage in upper urinary tract urothelial carcinoma: a step towards virtual biopsy
Authors: Abdulsalam Alqahtani, Sourav Bhattacharjee, Abdulrahman Almopti, Chunhui Li, Ghulam Nabi
Journal: International Journal of Surgery (2024)

Objectives: Upper tract urothelial carcinoma is a rare, aggressive lesion, with early detection a key to its management. This study aimed to utilise computed tomographic urogram data to develop machine learning models for predicting tumour grading and staging in upper urothelial tract carcinoma patients and to compare these predictions with histopathological diagnosis used as reference standards. Methods: Protocol-based computed tomographic urogram data from 106 patients were obtained and visualised in 3D. Digital segmentation of the tumours was conducted by extracting textural radiomics features. They were further classified using 11 predictive models. The predicted grades and stages were compared to the histopathology of radical nephroureterectomy specimens. Results: Classifier models worked well in mining the radiomics data and delivered satisfactory predictive machine learning models. The MultiLayer Panel showed 84% sensitivity and 93% specificity while predicting upper tract urothelial carcinoma grades. The Logistic Regression model showed a sensitivity of 83% and a specificity of 76% while staging. Similarly, other classifier algorithms (e.g., Support Vector classifier) provided a highly accurate prediction while grading upper tract urothelial carcinoma compared to clinical features alone or ureteroscopic biopsy histopathology. Conclusion: Data mining tools could handle medical imaging datasets from small (&lt;2 cm) tumours for upper tract urothelial carcinoma. The radiomics-based machine learning algorithms provide a potential tool to model tumour grading and staging with implications for clinical practice and the upgradation of current paradigms in cancer diagnostics. Clinical relevance: Machine learning based on radiomics features can predict upper tract urothelial cancer grading and staging with significant improvement over ureteroscopic histopathology. The study showcased the prowess of such emerging tools in the set objectives with implications towards virtual biopsy.
Reflection on analyzing the long-term quality of life between duodenum-preserving pancreatic head resection and pancreatoduodenectomy
Authors: Hanyun Tu, Sufei Yang, Rong Liu
Journal: International Journal of Surgery (2024)

aSchool of Medicine, Jinan University, Guangzhou, China. bDepartment of Cardiology, Daping Hospital, Army Medical University, Third Military Medical University, Chongqing, China cSichuan Institute of Product Quality Supervision and Inspection, Chengdu, China dGraduate School, The Chinese Academy of Sciences, Kunming, China Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. Published online ■ ■ *Corresponding author. Address: Sichuan Institute of Product Quality Supervision and Inspection, Chengdu 610100, China. E-mail address: [email protected] (R. Liu). This is an open access article distributed under the Creative Commons Attribution-ShareAlike License 4.0, which allows others to remix, tweak, and build upon the work, even for commercial purposes, as long as the author is credited and the new creations are licensed under the identical terms. http://creativecommons.org/licenses/by-sa/4.0/
Single stage management of suspected gallbladder cancer guided by intraoperative frozen section analysis: A retrospective cohort study
Authors: Serena Banh, Matyas Fehervari, Sara Flod, Payam Soleimani-Nouri, Antonio Leyte Golpe, Raida Ahmad, Madhava Pai, Duncan R.C. Spalding
Journal: International Journal of Surgery (2024)

The management of radiologically suspected gallbladder cancers (GBC) that lack definitive radiological features usually involves performing a first-stage routine laparoscopic cholecystectomy, followed by an open second-stage liver resection (segments IVB and V) and hilar lymphadenectomy (extended cholecystectomy) if subsequent formal histology confirms a malignancy. Performing a cholecystectomy with an intraoperative frozen section to guide the need for conversion to an extended cholecystectomy as a single-stage procedure has multiple benefits compared to a two-stage approach. However, the safety and efficacy of this approach have not yet been evaluated in a tertiary setting.
FDG PET/CT in a Case of Solitary Mixed Squamous Cell and Glandular Papilloma of the Lung With High CEA Level
Authors: Jun Zhang, Aisheng Dong, Yang Wang
Journal: Clinical Nuclear Medicine (2024)

Abstract Solitary mixed squamous cell and glandular papilloma of the lung is an extremely rare benign neoplasm. We describe FDG PET/CT findings in a case of solitary mixed squamous cell and glandular papilloma of the lung with high serum carcinoembryonic antigen level (63.3 ng/mL; reference, &lt;5 ng/mL). The tumor showed intense FDG uptake with SUV max of 23.8 mimicking lung cancer.
Reply to van der Sar <i>et al.</i>: Classifying Interstitial Lung Disease: Omics Are in the Air
Authors: Yong Huang, Shwu-Fan Ma, Imre Noth
Journal: American Journal of Respiratory and Critical Care Medicine (2024)

"Reply to van der Sar et al.: Classifying Interstitial Lung Disease: Omics Are in the Air." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp.
Reply to Zijlstra: Resilience and Stress Are Heterogenic Too, We Should Act Accordingly
Authors: Elie Azoulay, Frédéric Pochard, Laurent Argaud, Nancy Kentish-Barnes
Journal: American Journal of Respiratory and Critical Care Medicine (2024)

"Reply to Zijlstra: Resilience and Stress Are Heterogenic Too, We Should Act Accordingly." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp.
Classifying Interstitial Lung Disease: Omics Are in the Air
Authors: Iris G. van der Sar, Catharina C. Moor, Marlies S. Wijsenbeek
Journal: American Journal of Respiratory and Critical Care Medicine (2024)

"Classifying Interstitial Lung Disease: Omics Are in the Air." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp.
Electrical Impedance Tomography: A Monitoring Tool for Ventilation Induced Lung Injury
Authors: Isabella Fratti, Tommaso Pozzi, Guenter Hahn, Antonio Fioccola, Rosmery V. Nicolardi, Mattia Busana, Francesca Collino, Onnen Moerer, Luigi Camporota, Luciano Gattinoni
Journal: American Journal of Respiratory and Critical Care Medicine (2024)

"Electrical Impedance Tomography: A Monitoring Tool for Ventilation Induced Lung Injury." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp.
Pulmonary Hypertension and Lung Damage Associated with Prolonged Exposure to Patent Ductus Arteriosus in Very Preterm Infants
Authors: Eduardo Villamor, Gema E. Gonzalez-Luis
Journal: American Journal of Respiratory and Critical Care Medicine (2024)

"Pulmonary Hypertension and Lung Damage Associated with Prolonged Exposure to Patent Ductus Arteriosus in Very Preterm Infants." American Journal of Respiratory and Critical Care Medicine, 0(ja), pp.
Minimal Residual Disease Status in Multiple Myeloma 1 Year After Autologous Hematopoietic Cell Transplantation and Lenalidomide Maintenance Are Associated With Long-Term Overall Survival
Authors: Marcelo C. Pasquini, Paul K. Wallace, Brent Logan, Manmeet Kaur, Joseph D. Tario, Alan Howard, Yali Zhang, Claudio Brunstein, Yvonne Efebera, Nancy Geller, Sergio Giralt, Parameswaran Hari, Mary M. Horowitz, John Koreth, Amrita Krishnan, Heather Landau, George Somlo, Nina Shah, Edward Stadtmauer, Dan T. Vogl, David H. Vesole, Philip L. McCarthy, Theresa Hahn
Journal: Journal of Clinical Oncology (2024)

PURPOSE Prognostic Immunophenotyping in Myeloma Response (PRIMeR) is an ancillary study of minimal residual disease (MRD) assessment for multiple myeloma by next-generation multiparameter flow cytometry (MFC). Patients were enrolled on a three-arm randomized control trial (Blood and Marrow Transplants Clinical Trials Network 0702 Stem Cell Transplant for Myeloma in Combination of Novel Agents [STaMINA]; ClinicalTrials.gov identifier: NCT01109004 ). METHODS Four hundred and thirty-five patients consented to the MRD panel, which included 10 monoclonal antibodies measured via six-color MFC. MRD was measured at baseline/preautologous hematopoietic cell transplant (BL/preAutoHCT), premaintenance (PM), and 1 year (Y1) after AutoHCT with a sensitivity of 10 –5 to 10 –6 . The primary objective was to assess MRD-negative (MRD neg ) at 1 year after AutoHCT and progression-free survival and overall survival (PFS/OS). RESULTS Similar to the STaMINA results, at a median follow-up of 70 months, there was no significant difference in PFS/OS by treatment arm in the PRIMeR patients. MRD neg at all three time points was associated with significantly improved PFS, and MRD neg at Y1 had significantly longer OS. Multivariate analysis of PFS, adjusting for disease risk and treatment arm, demonstrated hazard ratios (HRs) in MRD-positive patients compared with MRD neg patients at BL, PM, and Y1 of 1.55 ( P = .0074), 1.83 ( P = .0007), and 3.61 ( P &lt; .0001), respectively. Corresponding HRs for OS were 1.19 ( P = .48), 0.88 ( P = .68), and 3.36 ( P &lt; .001). Patients with sustained MRD neg or who converted to MRD neg by Y1 had similar PFS/OS. CONCLUSION To our knowledge, this first, prospective US cooperative group, multicenter study demonstrates that MRD neg at Y1 after AutoHCT with lenalidomide maintenance is prognostic for improved 6-year PFS and OS. Serial MRD measurements may direct trials to test how further therapy may improve long-term PFS and OS.