tbuckley/cabot-search huggingface dataset:
Acute respiratory distress syndrome
Authors: Katherine D Wick, Lorraine B Ware, Michael A Matthay
Journal: BMJ (2024)

Abstract The understanding of acute respiratory distress syndrome (ARDS) has evolved greatly since it was first described in a 1967 case series, with several subsequent updates to the definition of the syndrome. Basic science advances and clinical trials have provided insight into the mechanisms of lung injury in ARDS and led to reduced mortality through comprehensive critical care interventions. This review summarizes the current understanding of the epidemiology, pathophysiology, and management of ARDS. Key highlights include a recommended new global definition of ARDS and updated guidelines for managing ARDS on a backbone of established interventions such as low tidal volume ventilation, prone positioning, and a conservative fluid strategy. Future priorities for investigation of ARDS are also highlighted.
Ferric Citrate for the Prevention of Renal Failure in Adults with Advanced CKD: The FRONTIER Trial
Authors: Geoffrey A. Block, Steven K. Burke, Martha Block, Stephanie Brillhart, Amanda Leppink, Gerard John Smits, Mohammad R. Mizani, Pablo E. Pergola, F. David Newby, Varshasb Broumand, Bryce Stephen Foote, Mary O. Dittrich
Journal: Journal of the American Society of Nephrology (2024)
Association between Median Liver Stiffness and Proteinuria among US Adults: NHANES, 2017-2020
Authors: Kamonluk Rodsom, Chutawat Kookanok, Sansanee Thotsiri, Methavee Poochanasri, Narathorn Kulthamrongsri, Voramol Rochanaroon, Ariya Mongkolporn, Tulaton Sodsri, Varissara Sinkajarern, Thutpharritchn Phoonakh, Ekamol Tantisattamo
Journal: Journal of the American Society of Nephrology (2024)
Higher Spot Urinary Sodium Concentration Is Associated with Better Decongestion and Lower Risk of AKI in Acute Heart Failure
Authors: Rolando Claure-Del Granado, Noelia B. Miranda-Velásquez, Sergio Villarroel-Espinoza, Edward J. Garcia-Peñaloza, Israel Danny Rivas Salazar
Journal: Journal of the American Society of Nephrology (2024)
Self-Efficacy Predicts Patient-Reported Outcomes Measurement Information System (PROMIS) Health-Related Quality of Life Outcomes in Turkish Patients on Dialysis Better than the 36-Item Short Form Health Survey (SF-36)
Authors: Krister Cromm, Ngoc Pham, Özlem Kuman Tunçel, Mirja Humpert, Tatiana De los Ríos, Manuela Stauss-Grabo, Gulay Asci, Ercan Ok, Hayriye Elbi
Journal: Journal of the American Society of Nephrology (2024)
Adjudication Methodology to Assess Novel Urine Biomarkers Panel Detection of Nephrotoxicant Exposure in Presence or Absence of KDIGO-Defined AKI to Support Biomarker Qualification
Authors: Nicholas M. King, Steven G. Coca, Steven C. Hoffmann, Patrick T. Murray, Jai Radhakrishnan, Katrina Jolene Peron, Gary Steven Friedman
Journal: Journal of the American Society of Nephrology (2024)
Effect of a Low-Protein Diet Supplemented with Ketoanalogues on Body Composition and Hand Grip Strength of Elderly Mexican Patients with CKD Attending a Nutritional Care Center
Authors: Nadia Iracema Aldana Solis, Abril Gutiérrez Espinoza, Julia Nava, Adriana Salinas Rico, Araceli Aguilar Gamiño, Sara De La Rosa Diez, Joel D. Kopple
Journal: Journal of the American Society of Nephrology (2024)
IgM-Positive Plasma Cells in Lip Biopsy Specimens from Patients with Tubulointerstitial Nephritis with IgM-Positive Plasma Cells (IgMPC-TIN)
Authors: Naoki Takahashi, Toshio Imafuku, Takahisa Kawaguchi, Akira Iguchi, Yawara Yamashita, Kenji Kasuno, Masayuki Iwano, Tadashi Toyama
Journal: Journal of the American Society of Nephrology (2024)
Ultrasound-Guided Diuretic Therapy in Type 1 Cardiorenal Syndrome: A Randomized, Double-Blind Controlled Trial
Authors: Victor Hugo Gomez Johnson, Erika Elizabet Jaime Borja, Alfredo Fuentes Mercado, Eder Jonathan Amaro Palomo, Romeo Arias Escarpulli, Rodrigo Gopar-Nieto, Salvador Lopez Gil
Journal: Journal of the American Society of Nephrology (2024)
Anti-slit Antibodies on Kidney Biopsy Identify Patients with Steroid-Resistant Nephrotic Syndrome Responsive to Second-Line Immunosuppressant and Hence Have a Good Prognosis
Authors: Valentina Raglianti, Maria Lucia Angelotti, Luigi Cirillo, Samuela Landini, Viviana Palazzo, Maria elena Melica, Giulia Antonelli, Carolina Conte, Benedetta Mazzinghi, Francesca Becherucci, Paola Romagnani
Journal: Journal of the American Society of Nephrology (2024)
Postkidney Transplant May-Thurner Syndrome Causing Ipsilateral Left Lower-Extremity Edema and Left Lower-Quadrant Kidney Allograft Dysfunction
Authors: Macaulay A. Onuigbo, Marios Prikis, Erin Berg, Rachel Preston, Andrew Myhre, Selena Patterson, Ema Allen, Jaime Pineda
Journal: Journal of the American Society of Nephrology (2024)
COP9 Signalosome CSN4 and CSN5 Subunits Protect NKCC2 against Endoplasmic Reticulum Stress and Cellular Hypoxia
Authors: Kamel Laghmani, Stephanie Kharma, Sylvie Demaretz, Dalal Bakhos Al Douaihy
Journal: Journal of the American Society of Nephrology (2024)
Cell-Intrinsic C3 and Complement Factor B from Proximal Tubular Epithelial Cells Drive Post-Injury Kidney Fibrosis
Authors: Tilo Freiwald, Md Tajmul, Jorge Luis Trujillo-Ochoa, Daniel Chauss, Nardos Tesfaye Cheru, Dhaneshwar Kumar, Baktiar O. Karim, Julius F.E. Jäger, Yubing Guo, Maja Gunkel, Claudia Kemper, Tobias B. Huber, Thorsten Wiech, Martin Kolev, Majid Kazemian, Didier Portilla, Behdad Afzali
Journal: Journal of the American Society of Nephrology (2024)
SHR6508, a Calcium-Sensing Receptor Agonist, in Patients on Hemodialysis Who Have Secondary Hyperparathyroidism: A Phase 2 Trial
Authors: Xueqing Yu, Zhiming Ye, Li Fan, Yuqing Chen, Pei Wang, Rui Yan, Bin Liu, Yong Wei, Hong Ye, Bi hu Gao, Xin Zhang, Xinyu Yang, Xue Yang
Journal: Journal of the American Society of Nephrology (2024)
Dietary Acid Reduction with Fruits and Vegetables or Sodium Bicarbonate to Avoid or Delay Need for Kidney Replacement Therapy (KRT) in Patients Initially with Stage 3 CKD: A 10-Year Randomized Trial
Authors: Nimrit Goraya, Jan Simoni, Maninder Kahlon, Nazan Aksan, Donald E. Wesson
Journal: Journal of the American Society of Nephrology (2024)
Comparison of Spot Creatinine Estimation by StatSensor Creatinine Meter and Serum Creatinine Estimation by Conventional Enzymatic Method
Authors: Manoj Chandrasekar, Manjunath Sanjeeva Shetty, Basavanagowdappa Hathur, Prashant Vishwanath, Akila Prashant, Praveen Kulkarni, Kiran K K, Naman Chandra, Abhijith Devaraju, Dennis Begos, John O. Oyelakin-Ogunbileje, Vishakantha Murthy
Journal: Journal of the American Society of Nephrology (2024)
Periadventitial Delivery of Nanoparticle-Encapsulated AZD8797 Reduces Venous Stenosis in a Murine Arteriovenous Fistula Model
Authors: Prabh G. Singh, Sreenivasulu Kilari, Alaura Lemieux, Jamie Kane, Sanjay Misra
Journal: Journal of the American Society of Nephrology (2024)
Clinical, Serologic, and Histologic Characteristics of Pauci-Immune Renal Vasculitis and Its Response to Treatment in a Mexican Population
Authors: Martin Benjamin Yama Estrella, Mario Alamilla-Sanchez, Jose H. Cano Cervantes, Mayra May Matias Carmona, Citlali Fernandez Vivar, Carolina Gonzalez-Fuentes, Manuel Camacho Luna, Nicte Alaide Ramos García, Michelle Sánchez, Fani Guadalupe Ruiz Rivera, Enrique Fleuvier Morales Lopez, Regina Canade Hernandez
Journal: Journal of the American Society of Nephrology (2024)
Prediction of Recovery of Kidney Function in Severe ANCA-Associated Glomerulonephritis
Authors: Megan Leffek, Kavita Gulati, Jennifer Scott, Gavin Chapman, Benoit Brilland, Cecilia Barnini, Vojtech Kratky, Jens Rathmann, Minhyung Kim, Li Jin Ooi, Zdenka Hruskova, Maria J. Stangou, Ajay Prabhakar Dhaygude, Abdulmecit Yildiz, Jean francois Augusto, Jung eun Lee, Andrea Hinojosa-Azaola, Juan M. Mejia-Vilet, Andreas Kronbichler, Neeraj Dhaun, Marten Segelmark, Mark Alan Little, Duvuru Geetha, Stephen Paul McAdoo, Silke R. Brix
Journal: Journal of the American Society of Nephrology (2024)
Can Post-Dilution Online Hemodiafiltration Provide a Valid Means of Preserving the Global Environment?
Authors: Kenji Sakurai, Yoshitaka Kurihara, Hiromi Hosoya, Fumi Yamauchi, Takeshi Saito, Daisuke Ishii, Toru Hyodo, Kenichi Kokubo
Journal: Journal of the American Society of Nephrology (2024)
Associations of Urine Epidermal Growth Factor with Kidney and Cardiovascular Outcomes in Individuals with CKD in SPRINT
Authors: Merve Postalcioglu, Ronit Katz, Simon Ascher, Pranav S. Garimella, Stein I. Hallan, Joachim H. Ix, Michael Shlipak
Journal: Journal of the American Society of Nephrology (2024)
Efficacy and Safety of Belimumab in Severe Lupus Nephritis: A Retrospective Single-Center Study
Authors: Ailima Aierken, Jing Zhuang, Shufen Yang, Dilina Yalikun, Chengren Xu, Changrong Zhang, Xuefei Tian, Hong Jiang
Journal: Journal of the American Society of Nephrology (2024)
Hydralazine-Associated Anti-neutrophilic Cytoplasmic Antibody (ANCA)-Associated Vasculitis: A Model of Drug-Associated Autoimmunity
Authors: Gang Xi, Olivier Lardinois, Peiqi Hu, Elizabeth A. McInnis, John S. Poulton, Meghan E. Free, Dhruti P. Chen, Evan Zeitler, Eve Wu, Vimal K. Derebail, J. Charles Jennette, Ronald Falk
Journal: Journal of the American Society of Nephrology (2024)
Bloodstream Infection Standardized Infection Ratios among ESKD Networks
Authors: Leticia A. Lamping, Jose E. Navarrete, Bria Marchelle Jarrell, Tamara L. Hoxworth, John Keenan, Kira Barbre, Lu Meng, Stephanie Clark, Delia Houseal, Shannon Novosad, Jonathan Edwards, Andrea L. Benin, Jeneita Bell
Journal: Journal of the American Society of Nephrology (2024)
Assessing Kidney Function Markers and Myocardial Perfusion Imaging with Thallium-201 in Patients with CKD
Authors: Wei-Yu Su, Yi-Ting Lin, Ming-Yen Lin, Mei-Chuan Kuo, Yi-Wen Chiu, Yi-chun Tsai, Jer-Ming Chang, Shang-Jyh Hwang, Ping-Hsun Wu
Journal: Journal of the American Society of Nephrology (2024)
Reliability of Time-Lapse High-Resolution Peripheral Quantitative CT (HR-pQCT) in Determining Bone Remodeling in Patients with ESKD
Authors: Minhao Zhou, Saghi Sadoughi, Lauren Go, Isabel Yu, Po-hung Wu, Isra Saeed, Bo Fan, Isidro B. Salusky, Thomas Nickolas, Joachim H. Ix, Galateia J. Kazakia
Journal: Journal of the American Society of Nephrology (2024)
In Vivo Evidence of Complement Requirement for Mesangioproliferative Activity of Immune Complexes Containing Galactose-Deficient IgA1 in IgA Nephropathy
Authors: Zina Moldoveanu, Stacy D. Hall, Graham Gurganus, Lea Novak, Zhi qiang Huang, Shihong Qiu, Todd J. Green, Jan Novak
Journal: Journal of the American Society of Nephrology (2024)
Correlation of Global Climate Change and Kidney Stone Awareness: A Temporal Trends Analysis, 2004-2023
Authors: Noppawit Aiumtrakul, Methavee Poochanasri, Chutawat Kookanok, Charat Thongprayoon, Supawadee Suppadungsuk, Pajaree Krisanapan, Wisit Cheungpasitporn
Journal: Journal of the American Society of Nephrology (2024)
Endothelial Glycocalyx Changes in Pregnancy: Relationship with Kidney Injury in Preeclampsia
Authors: Oscar Alejandro Garcia Valencia, Sonja Suvakov, Natasa Milic, Darah Dilmaghani, Vladimir Dokic, Paul Gavrilovici, Jennet Hatamova, Jing Miao, Vesna D. Garovic
Journal: Journal of the American Society of Nephrology (2024)
Metabolomic Analysis of Peritoneal Dialysis Effluent across Different Peritoneal Transport Types
Authors: Xiaoling Wang, Hasib Absar, Nadja Grobe, Mark Kakembo, Xin Wang, Gabriela Ferreira Dias, Lela Tisdale, Fansan Zhu, Laura Rosales M., Lin-Chun Wang, Maggie Han, Peter Kotanko
Journal: Journal of the American Society of Nephrology (2024)
A Novel Potassium Binder Sodium Zirconium Cyclosilicate to Enable RAAS Inhibitor (RAASi) Use in the Treatment of Patients with Diabetic Kidney Disease: The Crystal Study
Authors: Weiming Wang, Leyi Gu, Xiujuan Zang, Na Liu, Yangbin Pan, Chunming Jiang, Ying Li, Gengru Jiang, Zhiguo Mao, Jun Xue, Rong Zhou, Hao Xu, Jian Liu
Journal: Journal of the American Society of Nephrology (2024)
Association of Urinary Adhesion Molecules Derived from Endothelial Cells and Kidney Pathology in ANCA-Associated Glomerulonephritis
Authors: Tomoki Tanaka, Ryosuke Umeda, Shun Minatoguchi, Joichi Usui, Kunihiro Yamagata, Midori Hasegawa, Naotake Tsuboi
Journal: Journal of the American Society of Nephrology (2024)
Characterizing Kidney and Liver Cysts in Monoallelic PKHD1 Individuals Identified in a Population-Based Study
Authors: Doaa E. Elbarougy, Tabinda Jawaid, Hana Yang, Shannon K. McDonnell, Jacob A. Frank, Jun Ma, Adriana Gregory, Vicente E. Torres, Fouad T. Chebib, Christian Hanna, Timothy L. Kline, Nicholas B. Larson, Peter C. Harris
Journal: Journal of the American Society of Nephrology (2024)
Light Sheet Fluorescence Microscopy: A Novel Tool for Three-Dimensional Optical Reconstructions of Mouse Arteriovenous Fistulae in Control and Uremic Animals
Authors: Unimunkh Uriyanghai, Edward Moreira Bahnson, Christine Wai, Lianxia Li, Eric W. Livingston, Vinay A. Sudarsanam, Samuel Haddad, Huanjuan Su, Eyla C. Arteaga, Boyce E. Griffith, Prabir Roy-Chaudhury, Gang Xi
Journal: Journal of the American Society of Nephrology (2024)
Exploring the Effectiveness of Urea in Hyponatremia Due to Syndrome of Inappropriate Antidiuretic Hormone Secretion: A Comprehensive Systematic Review and Meta-Analysis
Authors: Abhi Lohana, Fnu Shivani, Sejal Neel, Subhash Chander, Syed Adil Mir Shah, Neeharika Muddana
Journal: Journal of the American Society of Nephrology (2024)
Sarcopenia in Patients on Hemodialysis in Brazil: Results of the SARC-HD Study
Authors: Heitor S. Ribeiro, Marvery P. Duarte, Otavio Nobrega, Fábio Augusto Silva Vieira, Maryanne Silva, Dário R. Mondini, Bruna Maggi Sant'Helena, Henrique Santos Disessa, Angélica Nickel Adamoli, Daiana C. Bundchen, Rodrigo de Rosso Krug, Antonio Jose Inda-Filho, Carla Maria Avesani, Barbara Perez Vogt, Maycon Moura Reboredo
Journal: Journal of the American Society of Nephrology (2024)
The Intersection between Chimeric Antigen Receptor T Cell (CAR-T) Therapy and the Kidneys: A Multicenter Study of Outcomes
Authors: Ahmad Matarneh, Sundus Sardar, Rafael Portela, Muhammad Abdulbasit, Navin Verma, Naman Trivedi, Nasrollah Ghahramani
Journal: Journal of the American Society of Nephrology (2024)
Treatment of Autosomal Dominant Tubulointerstitial Kidney Disease Uromodulin (ADTKD-UMOD) with Antisense Oligonucleotides
Authors: Kathy Ye Morgan, Nino Jungels, Christopher Greer, Stephanie Garcia, Emily G. Thompson, Tushare Jinadasa, Xuyu Tan, Kailash Adhikari, Vincent Guerlavais, Ryan Oliver
Journal: Journal of the American Society of Nephrology (2024)
Deficiency of Leucine-Rich α2-Glycoprotein 1 Suppresses Kidney Fibrosis Caused by Ischemia-Reperfusion Injury
Authors: Naohito Okami, Hiromichi Wakui, Kengo Azushima, Shinya Taguchi, Tomohiko Kanaoka, Kouichi Tamura
Journal: Journal of the American Society of Nephrology (2024)
Lessons Learned from Patient Engagement in the Polycystic Kidney Disease Research Resource Consortium (PKD RRC)
Authors: Vinamratha Rao, Susan Gleason, Jullie Hoggan, Sarit Neter, Taslima Rahman, Terry J. Watnick, Lisa M. Guay-Woodford, Reem Mustafa
Journal: Journal of the American Society of Nephrology (2024)
Outcomes of Real-World Adults with CKD Who Are Not Represented in Blood Pressure Target Trials
Authors: June Li, Jaejin An, Matt Mengnan Zhou, Maria E. Montez-Rath, Mengjiao Huang, Fang Niu, John J. Sim, Michelle Odden, Vivek Charu, Manjula Kurella Tamura
Journal: Journal of the American Society of Nephrology (2024)
Survival of COVID-19 Infection after Integrated Resource Planning Vaccination among Thai Patients on Hemodialysis: An Observational Cohort Study
Authors: Manoch Rattanasompattikul, Suchai Sritippayawan, Sukit Raksasuk, Pattharawin Pattharanitima, Thatsaphan Srithongkul
Journal: Journal of the American Society of Nephrology (2024)
Association of Glucose Variability with Coronary Artery Calcium Score in Patients with Nondialysis-Dependent CKD: Findings from KNOW-CKD
Authors: Dong Hoon Kang, Jong Hyun Jhee, Byounghwi Ko, Cheol Ho Park, Ga Young Heo, Hyung Woo Kim, Jung Tak Park, Seung Hyeok Han, Shin-Wook Kang, Tae-Hyun Yoo
Journal: Journal of the American Society of Nephrology (2024)
Dasatinib Blocks Mesangial Cell Activation by IgA1-Containing Immune Complexes in IgA Nephropathy In Vitro and In Vivo
Authors: Zhi qiang Huang, Stacy D. Hall, Joshua Charles Anderson, Zina Moldoveanu, Lea Novak, Shihong Qiu, Todd J. Green, Bruce A. Julian, Christopher D. Willey, Jan Novak
Journal: Journal of the American Society of Nephrology (2024)
Overweight/Obesity and Pulse Pressure: Kidney Prognosis in Young and Elderly Patients with ADPKD Regarding Attribute-Based Medicine (ABM) Insights
Authors: Hiroshi Kataoka, Toshio Mochizuki, Shun Manabe, Yusuke Ushio, Momoko Seki, Ken Tsuchiya, Kosaku Nitta, Junichi Hoshino
Journal: Journal of the American Society of Nephrology (2024)
Antineoplastic Agents Associated with Hypomagnesemia and Effect Modifiers for the Associations
Authors: Kodai Suzuki, Miho Murashima, Yuki Miyaguchi, Takahisa Kasugai, Tatsuya Tomonari, Minamo Ono, Masashi Mizuno, Takayuki Hamano
Journal: Journal of the American Society of Nephrology (2024)
Calcineurin Inhibitors Cause Kidney Fibrosis by Inactivating Pyruvate Dehydrogenase and Disrupting Energy Metabolism in Proximal Tubule Cells
Authors: Yasuhiro Oda, Hiroshi Nishi, Teruhiko Yoshida, Jeffrey B. Kopp, Masaomi Nangaku
Journal: Journal of the American Society of Nephrology (2024)
A Phase 1b, Double-Blind, Placebo-Controlled Study of DISC-0974, an Anti-hemojuvelin Antibody, in Patients with Nondialysis-Dependent CKD and Anemia
Authors: Samir Arora, Pablo E. Pergola, Arnold L. Silva, Geoffrey A. Block, Sima Bhatt, Akshay Buch, Olivia Pelletier, Will Savage
Journal: Journal of the American Society of Nephrology (2024)
Gut Microbiome and Olfactory Receptor 78 in Experimental AKI
Authors: Shishir Kumar Patel, Qisen Guo, Radhika Kapoor, Mahta Fateme Gooya, Mackenzie Kui, Lois J. Arend, Sanjeev Noel, Jennifer L. Pluznick, Hamid Rabb
Journal: Journal of the American Society of Nephrology (2024)
Safety and Efficacy of Selective Plasma Exchange vs. Conventional Plasma Exchange in Pretransplant Desensitization of ABO-Incompatible Kidney Transplantation
Authors: Takahiro Inoue, Norio Hanafusa, Yuki Kawaguchi, Kohei Unagami, Junichi Hoshino, Hideki Ishida, Toshio Takagi, Ken Tsuchiya
Journal: Journal of the American Society of Nephrology (2024)
SGLT2 Knockout Suppressed High Salt-Induced Organ Damage in Dahl Salt-Sensitive Rats
Authors: Hiroki Ito, Takuo Hirose, Shigemitsu Sato, Chika Takahashi, Risa Ishikawa, Akari Endo, Ikuko Yabana, Takefumi Mori
Journal: Journal of the American Society of Nephrology (2024)
Epithelial Injury Patterns Induced by Acute T Cell-Mediated Rejection in Kidney Transplants
Authors: Lorenz Jahn, Anna Maria Pfefferkorn, Janna Leiz, Vera Anna Kulow, Svjetlana Lovric, Jessica Schmitz, Jan H. Braesen, Irina Scheffner, Michael Fähling, Felix Aigner, Kai M. Schmidt-Ott, Wilfried Gwinner, Philip F. Halloran, Muhammad Imtiaz Ashraf, Christian Hinze
Journal: Journal of the American Society of Nephrology (2024)
Global Burden of Kidney Cancer Attributable to High Body Mass Index in 204 Countries and Territories, 1990-2021: Insights from the GBD 2021 Study
Authors: Ashwinikumar Shandilya, Shruthi Katam, Muhammad Waqas, Sravani Bhavanam, Shrey Goel, Saif Syed, Mohit Lakkimsetti, Vishrant Amin, Juhi Patel, Hardik Desai
Journal: Journal of the American Society of Nephrology (2024)
Pharmacologic Activation of CD11b Suppresses TLR7-Driven Proinflammatory Myeloid Signaling and Protects against Lupus Nephritis
Authors: Xiaobo Li, Viviana Jimenez, Billy Nguyen, Nishant Ranjan, David J. Cimbaluk, Jochen Reiser, Vineet Gupta
Journal: Journal of the American Society of Nephrology (2024)
Decreased Risk of Dialysis-Related Amyloidosis in the 2010s: Results from Japanese Nationwide Surveys in 2010 and 2017
Authors: Junichi Hoshino, Yusuke Ushio, Yuki Kawaguchi, Shun Manabe, Hiroshi Kataoka, Suguru Yamamoto, Masanori Abe, Norio Hanafusa
Journal: Journal of the American Society of Nephrology (2024)
To Be or Not to Be: Elevated Troponin and the Role of Secondary Prevention of Atherosclerotic Cardiovascular Disease in ESKD
Authors: Laverne Yip, Ammar Arif Vohra, Chee Yao Lim, Kenneth Johan, May Hnin Pwint Soe, Mirtha Camila Almanzar, Jorge Gutierrez, Pinal Patel, Juan Martinez Ortega, Rajiv Hans Solita Menghrajani, Jiwon Park, Chidinma Blossom Chijioke, Vidya Menon
Journal: Journal of the American Society of Nephrology (2024)
Metabolic Landscape of Naturally Occurring CKD in Cats: An Integrated Multiomics Study
Authors: Qinghong Li, Ornella Cominetti, Eugenia Migliavacca, James Holzwarth, Sonia Karaz, Mathieu Membrez, Charlotte Macron, Marie-Claude Courtet-Compondu, Stacie Summers, Vincenzo Sorrentino, Loïc Dayon
Journal: Journal of the American Society of Nephrology (2024)
Novel Serodiagnostic Biomarkers for IgA Nephropathy Using Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) Mass Spectrometry Glycoprofiling of IgA1
Authors: Shigeaki Nakazawa, Jan Novak, Norio Nonomura, Yoichi Kakuta
Journal: Journal of the American Society of Nephrology (2024)
Perspectives and Current Practices in the Provision of Sexual Health Support for People with CKD: A Survey of Canadian Health Care Providers
Authors: Meghan J. Elliott, Shannan Love, Sabrina Jassemi, Dwight Sparkes, Sandi M. Dumanski, Brenda Hemmelgarn, Clare Mckeaveney, Janine Farragher, Katie B. Ahrenholz, Gillian Crysdale, Nancy Verdin, Maoliosa Donald
Journal: Journal of the American Society of Nephrology (2024)
Social Risk Factors and Quality of Life in Patients on Hemodialysis
Authors: Hailey Yetman, Huei Hsun Wen, Lin-Chun Wang, Zijun Dong, Lela Tisdale, Yvette Foby, Mariam M. Olagoke, Stephan Thijssen, Peter Kotanko, Girish N. Nadkarni, Lili Chan
Journal: Journal of the American Society of Nephrology (2024)
Using Artificial Intelligence to Improve Tacrolimus Dosing in Kidney Transplant Patients
Authors: Sean A. Perez, Mingjia Huo, Linda Awdishu, Hayden H. Pour, Janice Kerr, Pengtao Xie, Adnan A. Khan, Kristin Mekeel, Shamim Nemati
Journal: Journal of the American Society of Nephrology (2024)
Liver transplantation for primary and secondary liver tumours. patient-level meta-analyses compared to unos conventional indications
Authors: Ruben Ciria, Tommy Ivanics, Daniel Aliseda, Marco Claasen, Felipe Alconchel, Felipe Gaviria, Javier Briceño, Giammauro Berardi, Fernando Rotellar, Gonzalo Sapisochin
Journal: Hepatology (2024)

Background &amp; Aims: Liver transplant (LT) for Transplant Oncology (TO) indications is being slowly adopted worldwide and has been recommended to be incorporated cautiously due to concerns on mid-long term survival and its impact on waiting list. Approach &amp; Results: We conducted four systematic reviews of all series on TO indications (intrahepatic (iCC) and perihilar cholangiocarcinoma (phCC)), liver metastases from neuroendocrine tumors (NET) and colorectal cancer (CRLM)) and compared them using patient-level meta-analyses to data obtained from UNOS database considering conventional daily-practice indications. Secondary analyses were done for specific selection criteria (Mayo-like protocols for phCC, SECA-2 for CRLM and Milan criteria for NET). A total of 112.014 LT were analyzed from 2005 to 2020 from the UNOS databases and compared with 345, 721, 494 and 103 patients obtained from meta-analyses on iCC and phCC, and liver metastases from NET and CRLM, respectively. Five-years overall survival was 53,3%, 56,4%, 68,6% and 53,8%, respectively. In Mantel-Cox one-to-one comparisons, survival of TO indications was superior to combined LT, second and third LT and and not statistically significant different to LT in recipients&gt;70 years and high BMI. Conclusions: Liver transplantation for TO indications has adequate 5-years survival rates, mostly when performed under the selection criteria available in literature (Mayo-like protocols for phCC, SECA-2 for CRLM and Milan for NET). Despite concerns on its impact on waiting list, some other LT indications are being performed with lower survival. These oncological patients should be given the opportunity to have a definitive curative therapy within validated criteria.