tbuckley/cabot-search huggingface dataset:
Allysine-Targeted Molecular MRI Enables Early Prediction of Chemotherapy Response in Pancreatic Cancer
Authors: Hua Ma, Shadi A. Esfahani, Shriya Krishna, Bahar Ataeinia, Iris Y. Zhou, Nicholas J. Rotile, Jonah Weigand-Whittier, Avery T. Boice, Andrew S. Liss, Kenneth K. Tanabe, Peter Caravan
Journal: Cancer Research (2024)

Abstract Neoadjuvant therapy is routinely used in pancreatic ductal adenocarcinoma (PDAC), but not all tumors respond to this treatment. Current clinical imaging techniques are not able to precisely evaluate and predict the response to neoadjuvant therapies over several weeks. A strong fibrotic reaction is a hallmark of a positive response, and during fibrogenesis, allysine residues are formed on collagen proteins by the action of lysyl oxidases. Here, we report the application of an allysine-targeted molecular MRI probe, MnL3, to provide an early, noninvasive assessment of treatment response in PDAC. Allysine increased 2- to 3-fold after one dose of neoadjuvant therapy with FOLFIRINOX in sensitive human PDAC xenografts in mice. Molecular MRI with MnL3 could specifically detect and quantify fibrogenesis in PDAC xenografts. Comparing the MnL3 signal before and 3 days after one dose of FOLFIRINOX predicted subsequent treatment response. The MnL3 tumor signal increased by 70% from day 0 to day 3 in mice that responded to subsequent doses of FOLFIRINOX, whereas no signal increase was observed in FOLFIRINOX-resistant tumors. This study indicates the promise of allysine-targeted molecular MRI as a noninvasive tool to predict chemotherapy outcomes. Significance: Allysine-targeted molecular MRI can quantify fibrogenesis in pancreatic tumors and predict response to chemotherapy, which could guide rapid clinical management decisions by differentiating responders from nonresponders after treatment initiation.
Sustained Low-Efficiency Dialysis with Regional Citrate Anticoagulation and a Standard Hemodialysis Machine in Critically Ill Patients with AKI
Authors: Francesca Di Mario, Filippo M. Fani, Paolo Greco, Caterina Maccari, Elisabetta Parenti, Tommaso Di Motta, Maria Teresa Farina, Giuseppe Regolisti, Enrico Fiaccadori
Journal: Journal of the American Society of Nephrology (2020)
Traditional and Non-Traditional Risk Factors and Their Influence on In-Hospital Mortality in Community- vs. Hospital-Acquired AKI
Authors: Maria Isabel Acosta-Ochoa, Armando Coca, Jimmy R. Sanchez Gil, Alicia Mendiluce
Journal: Journal of the American Society of Nephrology (2020)

Acosta-Ochoa, Maria Isabel; Coca, Armando; Sanchez Gil, Jimmy R.; Mendiluce, Alicia Author Information
Block Randomized Implementation of a Decision-Making Algorithm for Renal Replacement Therapy Initiation in AKI Compared with Standard Care on AKI-Related Outcomes
Authors: Yvelynne P. Kelly, Salman Ahmed, David E. Leaf, Ernest I. Mandel, Emily S. Robinson, Gearoid M. McMahon, Peter G. Czarnecki, David M. Charytan, Sushrut S. Waikar, Mallika L. Mendu
Journal: Journal of the American Society of Nephrology (2020)
Toward a Molecular Mechanism for Low-Molecular-Weight Proteinuria in Dent Disease
Authors: Katherine E. Shipman, Kimberly R. Long, Youssef Rbaibi, Catherine J. Baty, Ora A. Weisz
Journal: Journal of the American Society of Nephrology (2020)

Shipman, Katherine E.; Long, Kimberly R.; Rbaibi, Youssef; Baty, Catherine J.; Weisz, Ora A. Author Information
Characterization of the Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Response in Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Authors: Jared J. Lutsic, Yahya Alsawaf, Peter C. Harris, Vicente E. Torres, Maria V. Irazabal
Journal: Journal of the American Society of Nephrology (2020)

Lutsic, Jared J.; Alsawaf, Yahya; Harris, Peter C.; Torres, Vicente E.; Irazabal, Maria V. Author Information
Baseline Characteristics and Associations with Renal Function in a Greek Cohort of Polycystic Kidney Disease
Authors: George I. Tsirpanlis, Myrto Kostopoulou, Michaela Louka, Konstantina Kanellopoulou, Vasiliki Gkika, Stavros Fokas, Anastasia Karolina Koutsogianni, Konstantinos Lymperopoulos
Journal: Journal of the American Society of Nephrology (2020)
Overweight and Obesity Are Predictors of Pain in the HALT-PKD Studies
Authors: Wei Wang, Zhiying You, Berenice Y. Gitomer, Godela M. Brosnahan, Peter C. Harris, Dana Miskulin, Vicente E. Torres, Kaleab Abebe, Theodore I. Steinman, Alan S. Yu, Ronald D. Perrone, William E. Braun, Arlene B. Chapman, Michel Chonchol, Kristen L. Nowak
Journal: Journal of the American Society of Nephrology (2020)
Large-scale alternative polyadenylation-wide association studies to identify putative cancer susceptibility genes
Authors: Xingyi Guo, Jie Ping, Yaohua Yang, Xinwan Su, Xiao-Ou Shu, Wanqing Wen, Zhishan Chen, Yunjing Zhang, Ran Tao, Guochong Jia, Jingni He, Qiuyin Cai, Qingrun Zhang, Graham G. Giles, Rachel Pearlman, Gad Rennert, Pavel Vodicka, Amanda Phipps, Stephen B. Gruber, Graham Casey, Ulrike Peters, Jirong Long, Weiqiang Lin, Wei Zheng
Journal: Cancer Research (2024)

Abstract Alternative polyadenylation (APA) modulates mRNA processing in the 3′-untranslated regions (3′ UTR), affecting mRNA stability and translation efficiency. Research into genetically regulated APA has the potential to provide insights into cancer risk. In this study, we conducted large APA-wide association studies to investigate associations between APA levels and cancer risk. Genetic models were built to predict APA levels in multiple tissues using genotype and RNA sequencing data from 1,337 samples from the Genotype-Tissue Expression project. Associations of genetically predicted APA levels with cancer risk were assessed by applying the prediction models to data from large genome-wide association studies of six common cancers among European ancestry populations: breast, ovarian, prostate, colorectal, lung, and pancreatic cancers. A total of 58 risk genes (corresponding to 76 APA sites) were associated with at least one type of cancer, including 25 genes previously not linked to cancer susceptibility. Of the identified risk APAs, 97.4% and 26.3% were supported by 3′-UTR APA quantitative trait loci and colocalization analyses, respectively. Luciferase reporter assays for four selected putative regulatory 3′-UTR variants demonstrated that the risk alleles of 3′-UTR variants, rs324015 (STAT6), rs2280503 (DIP2B), rs1128450 (FBXO38), and rs145220637 (LDHA), significantly increased the posttranscriptional activities of their target genes compared with reference alleles. Furthermore, knockdown of the target genes confirmed their ability to promote proliferation and migration. Overall, this study provides insights into the role of APA in the genetic susceptibility to common cancers. Significance: Systematic evaluation of associations of alternative polyadenylation with cancer risk reveals 58 putative susceptibility genes, highlighting the contribution of genetically regulated alternative polyadenylation of 3′UTRs to genetic susceptibility to cancer.
Prevalence, Length of Stay, and Hospitalization of AKI in Patients with and Without Sjogren Syndrome
Authors: Mohamedanwar M. Ghandour, Yahya M. Osman Malik
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 84, October 2020. | DOI: 10.1681/ASN.20203110S184c
Cyst-Lumen Renal Stones in Mice Compound Heterozygous for Hypomorphic Pkd1V and Pkd1RC Alleles
Authors: Stephen C. Parnell, Heather A. Riddle, Shiqin Zhang, Feng Qian, James C. Williams, Jason R. Stubbs, Peter S. Rowe
Journal: Journal of the American Society of Nephrology (2020)
Prediction of AKI in Inpatient General Medical Ward Units
Authors: Cassandra Chiao, Rachel Urbas, Fauzia Osman, Tripti Singh
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 82, October 2020. | DOI: 10.1681/ASN.20203110S182a
Plasma Metabolites Do Not Change Significantly After 48 Hours in Patients on CRRT
Authors: Benjamin R. Griffin, Matthew Ray, Kristy Rolloff, John T. Brinton, Javier A. Neyra, J Pedro Teixeira, Kirby Mayer, Katja M. Gist, Muhammad Aftab, Diana I. Jalal, Julie Haines, Sarah Faubel
Journal: Journal of the American Society of Nephrology (2020)
Design of START: A Phase 2 Study Evaluating the Safety and Efficacy of RBT-1 on Preconditioning Response Biomarkers in Subjects Undergoing Cardiac Surgery
Authors: Bhupinder Singh, Philip T. Lavin, Andreas Orfanos, Stacey Ruiz, Donald J. Keyser, Alvaro F. Guillem, Richard A. Zager, Navdeep Tangri, Jean-Claude Tardif
Journal: Journal of the American Society of Nephrology (2020)
Angiotensin 1-7 as a Novel Biomarker of AKI in Pediatric Kidney Transplant Recipients
Authors: Lauren Ehrhardt-Humbert, Ashton Chen, Andrew M. South
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 79, October 2020. | DOI: 10.1681/ASN.20203110S179b
Volume Progression and Imaging Classification of Polycystic Liver in ADPKD
Authors: Kyongtae T. Bae, Cheng Tao, Robert Feldman, Alan S. Yu, Vicente E. Torres, Arlene B. Chapman, Ronald D. Perrone, Godela M. Brosnahan, Theodore I. Steinman, William E. Braun, Michal Mrug, William M. Bennett, Peter C. Harris, Doug Landsittel, Kaleab Abebe
Journal: Journal of the American Society of Nephrology (2020)
First in Canada: A Comprehensive Autosomal Dominant Polycystic Kidney Disease (ADPKD) Patient Registry in British Columbia (BC)
Authors: Sharon Gradin, Janet L. Williams, Adeera Levin, Ognjenka Djurdjev, Sanford Kong, Karin Jackson, Micheli U. Bevilacqua
Journal: Journal of the American Society of Nephrology (2020)
Curcumin Therapy to Treat Vascular Dysfunction in Children and Young Adults with Autosomal Dominant Polycystic Kidney Disease (ADPKD): Design and Baseline Characteristics of Participants
Authors: Heather Farmer-Bailey, Melissa A. Cadnapaphornchai, Zhiying You, Diana George, Wei Wang, Anna Jovanovich, Danielle Soranno, Berenice Y. Gitomer, Michel Chonchol, Kristen L. Nowak
Journal: Journal of the American Society of Nephrology (2020)
Ferroptosis Promotes Cyst Growth in Autosomal Dominant Polycystic Kidney Disease
Authors: Xiaoqin Zhang, Hao Ding, Xiaoyan Li, Peter C. Harris, Xiaogang Li
Journal: Journal of the American Society of Nephrology (2020)

Zhang, Xiaoqin; Ding, Hao; Li, Xiaoyan; Harris, Peter C.; Li, Xiaogang Author Information
One-Year AKI Stage 3 Outcome in Elderly Patients at a Secondary Care Hospital in the United Kingdom
Authors: Jeetendra R. Rathod, Matthew James, Syed A. Shafqat, Jonathan Kwan
Journal: Journal of the American Society of Nephrology (2020)

Rathod, Jeetendra R.; James, Matthew; Shafqat, Syed A.; Kwan, Jonathan Author Information
Urinalysis and Urine Electrolytes Among Patients with COVID-19 Infection and AKI
Authors: Vishnu S. Potluri, Sadichhya Lohani, Forrest F. Lindsay-McGinn, Claire A. Centeno, Jennifer Morganroth, Christy Moore, Felipe Teran, Nathaniel C. Reisinger
Journal: Journal of the American Society of Nephrology (2020)

Potluri, Vishnu S.; Lohani, Sadichhya; Lindsay-McGinn, Forrest F.; Centeno, Claire A.; Morganroth, Jennifer; Moore, Christy; Teran, Felipe; Reisinger, Nathaniel C. Author Information
Renin Levels Are Higher in Patients with AKI and Associate with Mortality and Major Adverse Kidney Events
Authors: Victor M. Ortiz-Soriano, Fabiola Gianella, Alexander H. Flannery, Xilong Li, Chirag R. Parikh, Sherry Mansour, Orson W. Moe, Stuart Goldstein, Javier A. Neyra
Journal: Journal of the American Society of Nephrology (2020)
Tolvaptan and Renal Function in Autosomal Dominant Polycystic Disease: A Two-Center Experience of 186 Cases
Authors: Yasuhiro Oda, Daisuke Ikuma, Hiroki Mizuno, Akinari Sekine, Masayuki Yamanouchi, Tatsuya Suwabe, Junichi Hoshino, Yoshifumi Ubara
Journal: Journal of the American Society of Nephrology (2020)

Oda, Yasuhiro; Ikuma, Daisuke; Mizuno, Hiroki; Sekine, Akinari; Yamanouchi, Masayuki; Suwabe, Tatsuya; Hoshino, Junichi; Ubara, Yoshifumi Author Information
Increased Phosphorylation of ACTN4 Leads to Podocyte Dysfunction and Focal Segmental Glomerulosclerosis Mimicking Disease-Causing Mutations
Authors: Di Feng, Mukesh Kumar, Jan Muntel, Susan B. Gurley, Gabriel Birrane, Isaac E. Stillman, Lai Ding, Minxian Wang, Saima Ahmed, Johannes S. Schlondorff, Seth L. Alper, Thomas Ferrante, Susan Marquez, Carlos F. Ng, Richard Novak, Donald E. Ingber, Hanno Steen, Martin R. Pollak
Journal: Journal of the American Society of Nephrology (2020)
Biological Efficacy and Safety of Niacinamide in Patients with Autosomal Dominant Polycystic Kidney Disease
Authors: Mireille El Ters, Xia Zhou, Rebecca J. Lepping, Pengcheng Lu, Jonathan D. Mahnken, William M. Brooks, Franz Winklhofer, Xiaogang Li, Alan S. Yu
Journal: Journal of the American Society of Nephrology (2020)
The Effect in Renal Function and Vascular Decongestion in Type 1 Cardiorenal Syndrome Treated with Two Strategies of Diuretics: A Randomized Clinical Trial
Authors: Jonathan Chavez, Miguel A. Ibarra-Estrada, Sergio J. Sánchez Villaseca, Juan Gómez Fregoso, Natashia L. Gongora, Andres Aranda, Joana G. Navarro gallardo, Oscar D. Sauceda Diaz, Guillermo Garcia-Garcia
Journal: Journal of the American Society of Nephrology (2020)
Combining Renal Arrest and Damage Biomarkers to Predict the Progression of AKI in Patients with Sepsis
Authors: Xiaobing Yang, Xiaolei Tao
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 80-81, October 2020. | DOI: 10.1681/ASN.20203110S180d
Incidence and Impact of AKI on Patients with Implantable Left Ventricular Assist Devices: A Meta-Analysis
Authors: Charat Thongprayoon, Wisit Cheungpasitporn, Panupong Hansrivijit, Tibor Fulop, Swetha Rani Kanduri, Michael A. Mao, Kianoush Kashani
Journal: Journal of the American Society of Nephrology (2020)
Adequacy of Kidney Follow-Up Among AKI Survivors After Hospital Discharge
Authors: Erin F. Barreto, Diana J. Schreier, Heather P. May, Kristin C. Mara, Kianoush Kashani, Alanna Chamberlain, Chung-Il Wi, Andrew D. Rule
Journal: Journal of the American Society of Nephrology (2020)

Barreto, Erin F.; Schreier, Diana J.; May, Heather P.; Mara, Kristin C.; Kashani, Kianoush; Chamberlain, Alanna; Wi, Chung-Il; Rule, Andrew D. Author Information
Elevated Expression of CaMK4 Contributes to mTOR-dependent Cell Proliferation and Cyst Growth of ADPKD Cells
Authors: Yan Zhang, Emily A. Daniel, Gail Reif, Darren P. Wallace
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 484, October 2020. | DOI: 10.1681/ASN.20203110S1484a
A New Insight into Hyperchloremic Metabolic Acidosis in Kidney Transplant Recipients: Increased Postglomerular Blood Flow Is a Key Condition for Calcineurin Inhibitor-Induced Renal Tubular Acidosis
Authors: Shuzo Kaneko, Joichi Usui, Kazuhiro Takahashi, Tomokazu Kimura, Akio Hoshi, Kunihiro Yamagata
Journal: Journal of the American Society of Nephrology (2020)

Kaneko, Shuzo; Usui, Joichi; Takahashi, Kazuhiro; Kimura, Tomokazu; Hoshi, Akio; Yamagata, Kunihiro Author Information
Characterizing AKI from Vancomycin-Associated Nephrotoxicity in Adult Non-ICU Patients at an Inner City Hospital: Incidence and Predictors
Authors: Gerald Fletcher, Levard G. Roberts, Sai S. Achi, Sheldon Ferguson, Maryam M. Handoo, Richard S. Sheppard, Aye M. Aung, Sudhanshu Jain, Suhaib A. Andrabi
Journal: Journal of the American Society of Nephrology (2020)
Ca2+-Permeable TRPV4 Channel Modulates Cystogenesis in ARPKD PCK453 Rats
Authors: Victor N. Tomilin, Naghmeh Hassanzadeh Khayyat, Oleg L. Zaika, Oleh Pochynyuk
Journal: Journal of the American Society of Nephrology (2020)

Tomilin, Victor N.; Khayyat, Naghmeh Hassanzadeh; Zaika, Oleg L.; Pochynyuk, Oleh Author Information
AKI in the Emergency Department: A Prospective Case-Control Study
Authors: Telma H. Ragnarsdóttir, Margret Kristjansdottir, Gisli Gislason, Vicente Sanchez-Brunete, Margret O. Tomasdottir, Olafur H. Samuelsson, Runolfur Palsson, Olafur S. Indridason
Journal: Journal of the American Society of Nephrology (2020)
AKI and Bleeding Risks Associated with Vitamin K Antagonists and Antiplatelet Agents in Patients with CKD
Authors: Solene M. Laville, Marie Metzger, Aghiles Hamroun, Oriane Lambert, Christian Jacquelinet, Maurice Laville, Luc Frimat, Denis Fouque, Christian Combe, Roberto Pecoits-Filho, Benedicte Stengel, Ziad Massy, Sophie Liabeuf
Journal: Journal of the American Society of Nephrology (2020)
CRRT Is Associated with Improved Kidney Recovery from Dialysis-Requiring AKI in a Multicenter Retrospective Analysis
Authors: John M. Arthur, Javier A. Neyra, Yevgeniya Gokun, Jihad S. Obeid, Milos N. Budisavljevic, David Redden, Michael J. Connor, Jin Chen, Lucas J. Liu, Mahanazuddin Syed, Ahmad Baghal, Jean Craig, Brian Harmon, Vinay Narasimha Krishna
Journal: Journal of the American Society of Nephrology (2020)
Effect of Sodium Bicarbonate on Kidney Injury: A Secondary Analysis of the BASE Pilot Trial
Authors: Kalani L. Raphael, Brett Larive, Tamara Isakova, Joachim H. Ix, Myles Wolf, Dominic S. Raj, Susan R. Mendley, Linda F. Fried, Cynthia A. Kendrick, Jennifer J. Gassman, Donald E. Wesson, Alfred K. Cheung
Journal: Journal of the American Society of Nephrology (2020)
The Real Life of Oral Alkalinization by Urologists and Nephrologists on Extracellular Volume: The AlcalUN Study
Authors: Jean-philippe Bertocchio, Julie Moriniere beaume, Lucile Figueres, Mickaël Bobot, Olivier Aubert, Louis De laforcade, Hamza Ayari, Thibault Dolley-Hitze, Victor Gueutin, Antoine Braconnier, Leonard Golbin, Salvatore Citarda, Guillaume Seret, Lisa Belaid, Raphael R. Cohen, Yosu Luque, Riyad N. Seervai, Camille Overs
Journal: Journal of the American Society of Nephrology (2020)
The Clinical Impact of Extended-Spectrum Beta-Lactamase-Producing Bacteria in Patients with Community-Acquired Acute Pyelonephritis in a Korean Hospital, 2010-2018
Authors: Se-Hee Yoon, Won Min Hwang, Sung-Ro Yun
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 72, October 2020. | DOI: 10.1681/ASN.20203110S172a
Renal Negative Pressure Treatment as a Novel Therapy for Cardiorenal Syndrome
Authors: Jennifer L. Asher, Christopher D. Maulion, Olyvia Gleason, Grace Meegan, Juan B. Ivey-Miranda, James H. Fleming, Veena Rao, Jeffrey M. Testani
Journal: Journal of the American Society of Nephrology (2020)

Asher, Jennifer L.; Maulion, Christopher D.; Gleason, Olyvia; Meegan, Grace; Ivey-Miranda, Juan B.; Fleming, James H.; Rao, Veena; Testani, Jeffrey M. Author Information
It’s Not a Bad Trip with This Acid: Sodium Thiosulfate Use in Refractory Metabolic Alkalosis
Authors: Melby Philip, Kamalanathan K. Sambandam
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 480, October 2020. | DOI: 10.1681/ASN.20203110S1480a
Pseudohypophosphatemia Caused by Severe Leukocytosis in a Patient with Chronic Lymphocytic Leukemia (CLL) and Tumor Lysis Syndrome (TLS)
Authors: Mehrian Jafarizade, Grace Y. Chong, Joseph C. Guzzo, Nelson P. Kopyt, Margaret Duffy
Journal: Journal of the American Society of Nephrology (2020)

Jafarizade, Mehrian; Chong, Grace Y.; Guzzo, Joseph C.; Kopyt, Nelson P.; Duffy, Margaret Author Information
Does Screening for Coronary Artery Disease Predict Cardiac Outcomes Following Renal Transplantation?
Authors: Ailish Nimmo, Dominic M. Taylor, Rommel Ravanan
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 57-58, October 2020. | DOI: 10.1681/ASN.20203110S157d
Role of Polycystin 2 in Endoplasmic Reticulum Calcium Release and Pathogenesis of Polycystic Kidney Disease
Authors: Biswajit Padhy, Jian Xie, Chou-Long Huang
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 484, October 2020. | DOI: 10.1681/ASN.20203110S1484c
Preoperative Urine Alpha 1 Microglobulin Levels Are Associated with AKI and Mortality After Cardiac Surgery
Authors: Jonathan G. Amatruda, Amit X. Garg, Heather Thiessen Philbrook, Eric McArthur, Steven G. Coca, Chirag R. Parikh, Michael Shlipak
Journal: Journal of the American Society of Nephrology (2020)
PKD1 Compared with PKD2 Genotype and Cardiac Hospitalizations in the HALT-PKD Studies
Authors: Cortney Steele, Zhiying You, Berenice Y. Gitomer, Godela M. Brosnahan, Peter C. Harris, Vicente E. Torres, Kaleab Abebe, Theodore I. Steinman, Alan S. Yu, Ronald D. Perrone, William E. Braun, Arlene B. Chapman, Michel Chonchol, Kristen L. Nowak
Journal: Journal of the American Society of Nephrology (2020)
Profound Lactic Acidosis due to Dextrose Infusion and the Role of Thiamine
Authors: Kristen R. Lile, Sarah Faubel
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 477, October 2020. | DOI: 10.1681/ASN.20203110S1477b
Availability, cost and affordability of essential medicines for chronic respiratory diseases in low-income and middle-income countries: a cross-sectional study
Authors: Marie Stolbrink, Obianuju B Ozoh, David M G Halpin, Rebecca Nightingale, Jamilah Meghji, Catherine Plum, Brian William Allwood, Shamanthi Jayasooriya, Kevin Mortimer
Journal: Thorax (2024)

Contemporary data on the availability, cost and affordability of essential medicines for chronic respiratory diseases (CRDs) across low-income and middle-income countries (LMICs) are missing, despite most people with CRDs living in LMICs. Cross-sectional data for seven CRD medicines in pharmacies, healthcare facilities and central medicine stores were collected from 60 LMICs in 2022–2023. Medicines for symptomatic relief were widely available and affordable, while preventative treatments varied widely in cost, were less available and largely unaffordable. There is an urgent need to address these issues if the Sustainable Development Goal 3 is to be achieved for people with asthma by 2030.
Urine NAG Is an Effective Clinical Parameter to Presume Disease Activity of Autosomal Dominant Polycystic Kidney Disease
Authors: Yuta Kogure, Kaori Takayanagi, Mai Aoyagi, Minoru Hatano, Takatsugu Iwashita, Tomonari Ogawa, Hajime Hasegawa
Journal: Journal of the American Society of Nephrology (2020)

Kogure, Yuta; Takayanagi, Kaori; Aoyagi, Mai; Hatano, Minoru; Iwashita, Takatsugu; Ogawa, Tomonari; Hasegawa, Hajime Author Information
The Effect of Trehalose on Autophagy-Related Proteins and Cyst Growth in a Hypomorphic Pkd1 Mouse Model of Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Authors: Daniel Atwood, Deepak Pokhrel, Carolyn N. Brown, Katharina Hopp, Charles L. Edelstein
Journal: Journal of the American Society of Nephrology (2020)

Atwood, Daniel; Pokhrel, Deepak; Brown, Carolyn N.; Hopp, Katharina; Edelstein, Charles L. Author Information
The Effect of Care Bundles for AKI: A Systematic Review and Meta-Analysis
Authors: Yixin Chen, Fangfang Zhou, Qun Luo
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 77-78, October 2020. | DOI: 10.1681/ASN.20203110S177d
A Fluidic Model of ARPKD Using Vascularized Kidney Organoids Identifies HIF-1 as a Potential Therapeutic Target
Authors: Ken Hiratsuka, Tomoya Miyoshi, Katharina T. Kroll, Navin R. Gupta, M. Todd Valerius, Takuya Matsumoto, Jennifer A. Lewis, Ryuji Morizane
Journal: Journal of the American Society of Nephrology (2020)
Elevated Serum Tenascin C Predicts All-Cause Mortality in Critically Ill Patients with Multiple Organ Dysfunction
Authors: Qionghong Xie, Xu Yunyu, Chuan-Ming Hao
Journal: Journal of the American Society of Nephrology (2020)

Journal of the American Society of Nephrology 31(10S):p 75, October 2020. | DOI: 10.1681/ASN.20203110S175b
Trends in Nephrology Follow-Up After an Episode of AKI in US Veterans
Authors: Ryann Sohaney, Houssam Mhanna, Maggie Yin, Diane Steffick, Vahakn Shahinian, Nilka Rios Burrows, Meda E. Pavkov, Raymond K. Hsu, Neil R. Powe, Kara Zivin, Rajiv Saran, Michael Heung
Journal: Journal of the American Society of Nephrology (2020)