tbuckley/cabot-search huggingface dataset:
THE PASTEUR INSTITUTE UNDER FIRE.
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Obituary: Leonard (“Johnnie”) Walker
Journal: BMJ (2004)

69-81 months, P = 0.05; doctor diagnosed asthma, 91 months, P = 0.005), it should be noted that, because of small numbers in some groups, the confidence intervals were wide and the results did not support the hypothesis.When we adjusted for potential confounding factors we detected no significant associations (P = 0.1-0.8).took part and the midwives for their cooperation and help in recruitment.The whole ALSPAC study team comprises interviewers, computer technicians, laboratory technicians, clerical workers, research scientists, volunteers, and managers who continue to make the study possible.The ALSPAC study is part of the European Longitudinal Study of Parents and Children initiated by the World Health Organization.Contributors:
International Clinics: a Quarterly of clinical Lectures on Medicine, Neurology, Pediatrics, Surgery, Genito-Urinary Surgery, Gynecology, Ophthalmology, Laryngology, Otology, and Dermatology.
Journal: JAMA (1893)

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AB0078 Role of IL-8 and Its Receptor in Anti-Citrullinated Protein Antibody Mediated Osteoclastogenesis in RA
Authors: Y. Liu, A. Krishnamurthy, A.H. Hensvold, V. Joshua, M. Sun, M. Engstrom, H. Wähämaa, V. Malmström, L.A. Jopling, B. Rethi, A. Catrina
Journal: Annals of the Rheumatic Diseases (2016)

<h3>Background</h3> Circulating levels of IL-8 is related to the bone loss associated with breast cancer metastasis. Recently, we have shown that anti-citrullinated protein antibodies (ACPA) can induce osteoclastogenesis. <h3>Objectives</h3> We aimed to investigate the role of IL-8 and its receptors in mediating osteoclastogenesis in presence or absence of ACPAs <h3>Methods</h3> IL-8 levels was measured by ELISA in serum of risk RA patients and synovial fluid samples of RA patients. CD14 positive monocytes were used to generate osteoclasts with M-CSF and RANKL. Inhibition of IL-8 and its receptor were tested with IL-8 neutralizing antibody or small molecule CXCR1/2 anta-agonist (Reparixin and SCH-527123) on osteoclasts (OC) in the presence or absence of ACPA. The number of the OC9s were counted in light microscope after TRAP staining. Cell counting kit 8 (CCK8) assay was performed to detect cytotoxicity. CXCR1 and CXCR2 expression was analyzed using flow cytometry and immunohistochemistry during different days of osteoclasts maturation. <h3>Results</h3> Increased IL-8 levels were observed in the serum of ACPA positive at risk RA healthy individuals and in synovial fluid of established ACPA positive RA patients. Exogenous IL-8 dose dependently increased OC numbers in presence of RANKL. IL-8 neutralizing antibody inhibited the OC numbers even in the presence of ACPA. Reparixin and SCH-527123 significantly inhibited RANKL mediated osteoclastogenesis at 100 μM concentration. No cytotoxicity of the drugs were detected with CCK8 assay. Immunohistochemistry staining confirmed the CXCR1/2 expression on OC precursors. We found high expression of IL-8 using immunohistochemistry on the inflammed RA synovium.We observed CXCR1 and CXCR2 expression with flow cytometry in the OC precursors at day 0 and in presence of RANKL the expression was completely lost at day 1 and it reappeared at day 4. <h3>Conclusions</h3> Our data provides insights in to the importance of IL-8 autocrine loop in RANKL and ACPA mediated OC development. IL-8 receptor blockade might be a novel way of targeting bone loss in RA. <h3>Disclosure of Interest</h3> None declared
Acute Respiratory Disease Associated With Adenovirus Serotype 14—Four States, 2006-2007
Journal: JAMA (2007)

Adenovirus serotype 14 (Ad14) is a rarely reported but emerging serotype of adenovirus that can cause severe and sometimes fatal respiratory illness in patients of all ages, including healthy young adults. In May 2006, an infant in New York aged 12 days died from respiratory illness caused by Ad14. During March-June 2007, a total of 140 additional cases of confirmed Ad14 respiratory illness were identified in clusters of patients in Oregon, Washington, and Texas. Fifty-three (38%) of these patients were hospitalized, including 24 (17%) who were admitted to intensive care units (ICUs); nine (5%) patients died. Ad14 isolates from all four states were identical by sequence data from the full hexon and fiber genes. However, the isolates were distinct from the Ad14 reference strain from 1955, suggesting the emergence and spread of a new Ad14 variant in the United States. No epidemiologic evidence of direct transmission linking the New York case or any of the clusters was identified. This report summarizes the investigation of these Ad14 cases by state and city health authorities, the U.S. Air Force, and CDC. State and local public health departments should be alert to the possibility of outbreaks caused by Ad14.
The cost of clinical laboratory testing
Authors: P. A. Brown
Journal: JAMA (1974)

THE patient visiting your office is concerned not only with the problem of his illness but also with what this illness is going to cost him. Once he has entered your office, he has already eliminated the problem of quality in his own mind. Clinical laboratory tests, however, in many instances are not performed by the examining physician. Therefore, the physician should discuss three important aspects of the clinical laboratory tests with the patient: quality, service, and economy. <h3>Quality</h3> In this area, it should be pointed out to the patient which laboratory tests are being performed in the doctor's office for which the physician assumes full responsibility. When the laboratory tests are referred to an outside laboratory, some discussion of that laboratory may be in order. At the present time, there are more than 7,500 outpatient clinical laboratories in the United States. Numerous states have laws governing their operation and
ABSTRACTS
Authors: Joseph Ross, Helen Belding, Winston-Salem Maier, Robert Chodos, Netou Ek, Roger Crafts, Charles Rath, Washington Dasgupta, Jean Soulier, Solomon Estren, York Ram, M Su#{225}rez, Juan Puerto, Rico Oliver, P Jones, Timothy Talbot, Philip Wagley, C Kempe, F Rivas, F Morales, L Ill, B Laski, ! Al, C Darte, W Snelling, J Al, B Snelling, S Laski, W Jackson, A Quick, C Hussey
Journal: Blood (1952)
Reverse Amortization
Authors: Sylvia S. Villarreal
Journal: Annals of Internal Medicine (2016)

Ad Libitum19 January 2016Reverse AmortizationSylvia S. Villarreal, Med, MPHSylvia S. Villarreal, Med, MPHFrom Houston, Texas.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M15-2060 Audio Reading - “Reverse Amortization” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Reverse Amortization," by S.S. Villarreal. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail In memory of DSJI enter her home's palpable emptiness—so unlike your usual bearish embrace.Your boyish smile punctuated seven decadesof full engagement. Terry—smaller, conscriptedas widow—is surrounded by remnants of a tandem life.Two sets of golf clubs slumped against the wallbear hushed witness to the abrupt cessation of sharedpleasures. Our conversation circles aroundyour sudden departure—an accounting of the final hours.in ... Author, Article, and Disclosure InformationAffiliations: From Houston, Texas.Current Author Address: Sylvia S. Villarreal, MEd, MPH, McGovern Center for Humanities and Ethics, 6431 Fannin Street, Suite JJL 410, Houston, TX 77030; e-mail, Sylvia.S.[email protected]tmc.edu. PreviousarticleNextarticle Advertisement Audio Reading - “Reverse Amortization” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Reverse Amortization," by S.S. Villarreal. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 19 January 2016Volume 164, Issue 2Page: 124KeywordsMemory ePublished: 19 January 2016 Issue Published: 19 January 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
MATTHEW DOBSON (1735?-1784) CLINICAL INVESTIGATOR OF DIABETES MELLITUS
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE 2.5-MINUTE KILOMETER
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Femoral Head Prosthesis Increasingly Popular With Orthopedic Surgeons
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Lungentuberkulose.
Journal: JAMA (1923)

In spite of the fact that the author offers nothing new, and admits it, he has presented a book which cannot fail to be of help to any one who wants a short, concise treatise on tuberculosis of the lungs. The book contains numerous quotations, but these do not detract from its readableness. When Dr. Amrein presents his own views, he is conservative and clear. He gives space to palpation in the diagnosis of tuberculosis more freely than has any other German writer with whom we are acquainted. In the matter of diagnosis, he points out, quite correctly, that the average physician fails to differentiate between tuberculous infection and active tuberculosis. He calls attention to the man with an inactive tuberculosis, even an open case, who may be able to earn a livelihood for himself and his family, and puts the pertinent query: "When shall we treat the patient and
From the Centers for Disease Control and Prevention. Progress toward global poliomyelitis eradication, 1985-1994
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mortality in patients treated for pulmonary embolism
Authors: J. S. Alpert
Journal: JAMA (1976)

The hospital course of 144 consecutive patients with pulmonary embolism (PE) demonstrated by pulmonary angiography was reviewed to determine the mortality of patients with treated PE. Twelve patients (8%) died of PE, and eight died of causes other than PE; 124 (86%) survived. Pulmonary embolism was the primary cause of death in only four of the 12 patients who died of PE. Pulmonary embolism contributed to the death of eight other patients, each of whom had associated potentially lethal disease, particularly heart disease. The most important factor affecting mortality was shock due to acute right ventricular failure secondary to massive PE (mortality, 32%). Mortality was not related to magnitude of PE per se; the mortality of patients with massive PE without shock (6%) was the same as that for patients with submassive PE (5%). Patients with PE who survive long enough to have the diagnosis established and appropriate prophylactic therapy begun have an excellent prognosis, unless they have associated severe medical disease. (<i>JAMA</i>236:1477-1480, 1976)
The distribution of organs for liver transplantation
Authors: D. J. Norman
Journal: JAMA (1994)

Prevalence of Homes Withoul Guns, % Potentially preventable homicides and suiCIdes by prevalence of homes withou1 guns: United States.1988 through 1990.RR Indicates unadjusted risk of homICide or suicide from guns in home; and p. baseline prevalence of homes with guns.effort to kill.Also, there is no evidence of compensatory increases in homicides involving other weapons when societal firearm access is restricted.Case fatality rates for suicides attempted with a gun are much higher than for suicides attempted otherwise.s Crossnational evidence suggests that where the favored means of committing suicide is removed there is a decrease in suicide.s ~iven th~t guns are the favored means of committing suicide In the Uruted States, some people may be less likely to choose other means if denied firearm access.Suicidal people are typically ambivalent about taking their lives, and the period at risk may be fleeting.Cook's view reflects our own: "The argument here is not that the availability onethal means is the sole determinant of.suicide rates but, rather, that the availability oflethal means Influences the extent to which suicidal impulses are translated into complete suicides."sThe limitations of our approach include using risk estimates l .2 that may not accurately reflect the population's risk and not adjusting for all confounding factors (note that the adjusted risk estimates of both case-control studies were higher than the unadjusted estimates l .2).It would appear that decreasing the prevalence of guns in the home could be an important part of a national strategy to prevent homicide and suicide.
Allergic reaction of penicillin present in milk
Authors: K. Wicher
Journal: JAMA (1969)

An allergic reaction developed in a patient, highly sensitive to penicillin, after ingestion of milk. This milk was examined by both bacteriological and immunological assays and was found to contain approximately 10 units/ml of penicillin. It was concluded that the allergic reaction of the patient was due to the penicillin in the milk.
"Sugared Condensed Milk: Vitamin C Content."
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Malignant Reticuloses Localized in the Bone Marrow; Diagnosis by Biopsy of Bone Marrow
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Spontaneous bacterial myositis
Authors: P. H. Altrocchi
Journal: JAMA (1971)

Spontaneous bacterial myositis is a relatively common affliction in the tropics but, for unknown reasons, is rare in temperate climates. Because of its rarity, correct diagnosis may be delayed. Patients have localized muscle pain, swelling, and tenderness, with or without fever. Antibiotics and surgery usually yield excellent results, but the condition can be fatal.
The diagnostic challenge of nonburrowing mite bites. Cheyletiella yasguri
Authors: E. D. Shelley
Journal: JAMA (1984)

Endemic pruritus in a family of four proved to be caused by the "bite and run" habits of the<i>Cheyletiella yasguri</i>mites that lived on the family dog. The mystery was solved only after the 6-year-old daughter experienced an explosive attack of pruritic papules after taking a nap in the dog's sleeping box. Virtually invisible ectoparasites remain a common cause of endemic pruritus within families. Since these patients show no acarologic, clinical, or laboratory evidence for the cause of their itch, a good rule remains,<i>cherchez le chien</i>. (<i>JAMA</i>1984;251:2690-2691)