Erythema Gyratum Repens Secondary to Pulmonary Tuberculosis
Authors: Caitlin A. Contag, Nolan Maloney, Ralph Tayyar, Maria Alexandrova Aleshin, Roberto Andres Novoa, Dora Yukwai Ho
Journal: Annals of Internal Medicine (2023)

Letters14 March 2023Erythema Gyratum Repens Secondary to Pulmonary TuberculosisCaitlin A. Contag, MD, Nolan Maloney, MD, Ralph Tayyar, MD, Maria Alexandrova Aleshin, MD, Roberto Andres Novoa, MD, Dora Yukwai Ho, MD, PhDCaitlin A. Contag, MDDivision of Infectious Diseases & Geographic Medicine, Department of Medicine, Stanford University, Stanford, CaliforniaSearch for more papers by this author, Nolan Maloney, MDDepartment of Dermatology, Stanford University, Stanford, CaliforniaSearch for more papers by this author, Ralph Tayyar, MDDivision of Infectious Diseases & Geographic Medicine, Department of Medicine, Stanford University, Stanford, CaliforniaSearch for more papers by this author, Maria Alexandrova Aleshin, MDDepartment of Dermatology, Stanford University, Stanford, CaliforniaSearch for more papers by this author, Roberto Andres Novoa, MDDepartment of Dermatology and Department of Pathology, Stanford University, Stanford, CaliforniaSearch for more papers by this author, Dora Yukwai Ho, MD, PhDDivision of Infectious Diseases & Geographic Medicine, Department of Medicine, Stanford University, Stanford, CaliforniaSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L22-0453 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: Erythema gyratum repens (EGR) is a striking dermatologic phenomenon associated with underlying malignancy in approximately 70% of cases (1). However, in the remaining 30% of cases, underlying etiologies are broad, from cutaneous immune deposition associated with autoimmune diseases to messenger RNA–based vaccines against COVID-19 (2, 3). Sometimes no underlying cause can be identified. Rarely tuberculosis (TB) has been reported as a possible trigger (4). However, the relationship between EGR and TB has not been well documented. Here, we report a case of EGR associated with pulmonary TB.Objective: To describe an unusual cutaneous complication of TB to help facilitate ...References1. Rongioletti F, Fausti V, Parodi A. Erythema gyratum repens is not an obligate paraneoplastic disease: a systematic review of the literature and personal experience. J Eur Acad Dermatol Venereol. 2014;28:112-5. [PMID: 22830929] doi:10.1111/j.1468-3083.2012.04663.x CrossrefMedlineGoogle Scholar2. Sussman M, Zhai L, Morquette A, et al. Annular bullous diseases. Clin Dermatol. 2022;40:516-28. [PMID: 34979265] doi:10.1016/j.clindermatol.2021.12.012 CrossrefMedlineGoogle Scholar3. Niebel D, Wilhelmi J, De Vos L, et al. Annular plaques mimicking Rowell's syndrome in the course of coronavirus disease 2019 mRNA vaccines: an overlooked phenomenon. J Dermatol. 2022;49:151-6. [PMID: 34693548] doi:10.1111/1346-8138.16210 CrossrefMedlineGoogle Scholar4. Barber PV, Doyle L, Vickers DM, et al. Erythema gyratum repens with pulmonary tuberculosis. Br J Dermatol. 1978;98:465-8. [PMID: 638054] doi:10.1111/j.1365-2133.1978.tb06543.x CrossrefMedlineGoogle Scholar5. Takwoingi Y, Whitworth H, Rees-Roberts M, et al. Interferon gamma release assays for Diagnostic Evaluation of Active tuberculosis (IDEA): test accuracy study and economic evaluation. Health Technol Assess. 2019;23:1-152. [PMID: 31138395] doi:10.3310/hta23230 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Caitlin A. Contag, MD; Nolan Maloney, MD; Ralph Tayyar, MD; Maria Alexandrova Aleshin, MD; Roberto Andres Novoa, MD; Dora Yukwai Ho, MD, PhDAffiliations: Division of Infectious Diseases & Geographic Medicine, Department of Medicine, Stanford University, Stanford, CaliforniaDepartment of Dermatology, Stanford University, Stanford, CaliforniaDepartment of Dermatology and Department of Pathology, Stanford University, Stanford, CaliforniaDisclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L22-0453.Corresponding Author: Caitlin A. Contag, MD, Division of Infectious Diseases & Geographic Medicine, Department of Medicine, Stanford University, 300 Pasteur Drive, L-134, Stanford, CA 94304; e-mail, cacontag@stanford.edu.This article was published at Annals.org on 14 March 2023. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics May 2023Volume 176, Issue 5Page: 733-735KeywordsAutoimmune diseasesBiopsyDermatologyErythemaEtiologyInfectious diseasesLesionsLungsRashesTuberculosis ePublished: 14 March 2023 Issue Published: May 2023 Copyright & PermissionsCopyright © 2023 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...