AB1689 CROSS-CULTURAL ADAPTATION AND VALIDATION OF THE TURKISH VERSION OF THE FLARE OA QUESTIONNAIRE FOR HIP AND KNEE OSTEOARTHRITIS
Authors: M. T. Duruöz, H. H. Gezer, E. Jonathan, M. Soudant, F. Guillemin
Journal: Annals of the Rheumatic Diseases (2023)

<h3>Background</h3> The Flare-OA self-reported questionnaire with five domains (painful, swelling, stiffness, consequences of symptoms, and psychological aspects) (0-100) was recently developed to measure the occurrence and severity of flares in the knee and hip osteoarthritis (OA). <h3>Objectives</h3> This study aimed to translate and cross-culturally adapt the Turkish version of the FLARE-OA questionnaire according to the results of the French/English version using classical psychometric analysis methods. <h3>Methods</h3> The French/English version of the FLARE-OA questionnaire was cross-culturally adapted and translated into Turkish following an established forward–backward translation procedure. After an expert committee reviewed the Turkish version, the final version was checked for the translation's understandability, interpretation, and cultural relevance with ten patients. Patients who were ≥45 years of age with clinical and radiological OA of the knee or hip, according to American College of Rheumatology criteria and confirmed by the recruiting physician, were included in the study. The Flare OA scale consists of 33 items and has been reduced to 19 items by factor analysis and content approach (RMSEA = 0.06; CFI = 0.96; TLI = 0.94) [1]. The reliability of Flare-OA was assessed by internal consistency (Cronbach's alpha coefficient). Face, content, and construct validity (convergent) were evaluated. The correlations of the Flare-OA with the Hip Disability and Osteoarthritis Outcome score (HOOS), Knee Injury and Osteoarthritis Outcome Score (KOOS), and the Mini Osteoarthritis Knee and Hip Quality of Life Questionnaire (Mini-OAKHQOL) were assessed for convergent validity. <h3>Results</h3> A total of 185 (71.9% females) patients with knee or hip OA with a mean age of 63.2 (SD:9.1) years participated in the study. One hundred-sixty (86.5%) of the patients had knee OA, 25(13.5%) had hip OA, and 70 (37.8%) had experienced worsening of the knee or hip OA during the last four weeks. The confirmatory factorial analysis retained a model with 19 items (RMSEA=0.08; SRMR =0.05; and CFI =0.95). Internal consistency Cronbach's alpha coefficient was 0.987 (95% CI: 0.984 - 0.990) for 33-item and 0.978 (95% CI: 0.973 - 0.982) for 19-item. The intraclass correlation coefficient was 0.913 and 0.915 for the test–retest reliability of the 33 and 19 items, respectively. Sensitivity to change was good in patients improving (SRM 1.2 and 1; 33 and 19 items, respectively) over the period. The discriminant validity was evidenced by a significant score difference (36.2 and 36.6; 33 and 19 items, respectively) between patients with and without flare. Pearson's correlation coefficients of the Flare-OA questionnaire with the other parameters for construct validity are represented in Table 1. <h3>Conclusion</h3> This study demonstrated that both the 33 and 19-items Turkish versions of the Flare OA questionnaire are reliable and valid tools for assessing flaring in patients with knee and hip OA. <h3>Reference</h3> [1] Traore, Y. et al. (2022). Development and validation of the Flare-OA questionnaire for measuring flare in knee and hip osteoarthritis. Osteoarthritis and cartilage, 30(5), 689–696. <h3>Acknowledgements:</h3> NIL. <h3>Disclosure of Interests</h3> None Declared.