tbuckley/cabot-search huggingface dataset:
Optical Genome Mapping for Genome-Wide Structural Variation Analysis in Hematologic Malignancies: A Prospective Study Demonstrates Additional Findings Compared to Standard-of-Care (SOC) Cytogenomic Methods
Authors: Stephen J. Wicks, Marissa Younan, Trilochan Sahoo, Jen Hauenstein, Anusha Mylavarapu, Beth Matthews, Karine Hovanes, Meena Naik, Nishit Ojha, Amey Panchal, Yesheswini Naik, Rahul Arora, Vishwadeep Khushoo, Vasu Babu, Nishad Dhakate, Poonam Jain, Punit Jain, Govind Babu, Sandeep Rao, Sachin Jadhav
Journal: Blood (2023)
Salvage Autologous Transplant and Lenalidomide Maintenance Versus Continuous Lenalidomide/Dexamethasone for Relapsed Multiple Myeloma: Long Term Follow up Results of the Randomized GMMG Phase III Multicenter Trial Relapse
Authors: Marc-Andrea Baertsch, Jana Schlenzka, Thomas Hielscher, Marc S. Raab, Sandra Sauer, Maximilian Merz, Elias K. Mai, Carsten Müller-Tidow, Steffen Luntz, Anna Jauch, Peter Brossart, Martin Goerner, Stefan Klein, Bertram Glass, Peter Reimer, Ullrich Graeven, Roland Fenk, Mathias Hänel, Ivana von Metzler, Lindemann Hans W., Christof Scheid, Axel Nogai, Hans Salwender, Richard Noppeney, Britta Besemer, Katja Weisel, Hartmut Goldschmidt
Journal: Blood (2023)
Long-Term Results from the Optic Trial: A Dose-Optimization Study of 3 Starting Doses of Ponatinib
Authors: Jorge Cortes, Michael Deininger, Elza Lomaia, Beatriz Moiraghi, Soledad Undurraga, Carolina Pavlovsky, Charles Chuah, Tomasz Sacha, Jeffrey H. Lipton, James McCloskey, Andreas Hochhaus, Philippe Rousselot, Gianantonio Rosti, Hugues de Lavallade, Anna Turkina, Lori Maness, Moshe Talpaz, Michael Mauro, Vickie Lu, Alexander Vorog, Jane F Apperley
Journal: Blood (2023)
Prevalence of Peripheral Neuropathy (PN) Among Patients with Asymptomatic Monoclonal Gammopathies: A Clinical &amp; Electrophysiological Study
Authors: Panagiotis Zis, Rodanthi Syrigou, Stella Fanouraki, Maria Gavriatopoulou, Despina Fotiou, Foteini Theodorakakou, Vasiliki Spiliopoulou, Maria Roussou, Ioannis Ntanasis-Stathopoulos, Panagiotis Malandrakis, Evangelos Eleutherakis-Papaiakovou, Magdalini Migkou, Evangelos Terpos, Meletios A. Dimopoulos, Efstathios Kastritis
Journal: Blood (2023)
B-Cell Maturation Antigen (BCMA) Expression and Clinical Features of Plasmablastic Lymphoma (PBL)
Authors: Ning Dong, Hailing Zhang, Jinming Song, Jamila Mammadova, Bijal D. Shah, Hayder Saeed, Ariel F. Grajales-Cruz, Leidy Lismeris Isenalumhe, Sameh Gaballa, Celeste M. Bello, Lubomir Sokol, Javier Pinilla-Ibarz, Julio C Chavez
Journal: Blood (2023)
Tumor Mutational Burden As a Prognostic Factor in Diffuse Large B-Cell Lymphoma
Authors: Rosalie Griffin, Kerstin Wenzl, Vivekananda Sarangi, Lisa M. Rimsza, Rebecca King, Andrew L. Feldman, Matthew J. Maurer, Grzegorz S. Nowakowski, Brian K. Link, Thomas M. Habermann, Nicholas Stong, C. Chris Huang, Anita K. Gandhi, Susan L. Slager, Anne J. Novak, James R. Cerhan
Journal: Blood (2023)
Integrated Methylation and Transcriptional Landscape and Evolution of Pediatric AML
Authors: Benjamin J Huang, Hamid Bolouri, Colin Y. Smith, Jim Wang, Rhonda E Ries, Elizabeth Conran, Alan S Gamis, Richard Aplenc, Todd A. Alonzo, Xiaotu Ma, Timothy Junius Triche, Jason E Farrar, Soheil Meshinchi
Journal: Blood (2023)
Serial Circulating Tumor DNA Analysis with a Tumor-Naïve Next-Generation Sequencing Panel Detects Minimal Residual Disease and Predicts Outcome in Ovarian Cancer
Authors: Jinho Heo, Yoo-Na Kim, Saeam Shin, Kyunglim Lee, Ji-Hyun Lee, Yong Jae Lee, Zisun Choi, Jihyang Park, Seungki Min, Sang Wun Kim, Jong Rak Choi, Sunghoon Kim, Seung-Tae Lee, Jung-Yun Lee
Journal: Cancer Research (2023)

Abstract Circulating tumor DNA (ctDNA) may aid in personalizing ovarian cancer therapeutic options. Here, we aimed to assess the clinical utility of serial ctDNA testing using tumor-naïve, small-sized next-generation sequencing (NGS) panels. A total of 296 patients, including 201 with ovarian cancer and 95 with benign or borderline disease, were enrolled. Samples were collected at baseline (initial diagnosis or surgery) and every 3 months after that, resulting in a total of 811 blood samples. Patients received adjuvant therapy based on the current standard of care. Cell-free DNA was extracted and sequenced using an NGS panel of 9 genes: TP53, BRCA1, BRCA2, ARID1A, CCNE1, KRAS, MYC, PIK3CA, and PTEN. Pathogenic somatic mutations were identified in 69.2% (139/201) of patients with ovarian cancer at baseline but not in those with benign or borderline disease. Detection of ctDNA at baseline and/or at 6 months follow-up was predictive of progression-free survival (PFS). PFS was significantly poorer in patients with detectable pathogenic mutations at baseline that persisted at follow-up than in patients that converted from having detectable ctDNA at baseline to being undetectable at follow-up; survival did not differ between patients without pathogenic ctDNA mutations in baseline or follow-up samples and those that converted from ctDNA positive to negative. Disease recurrence was also detected earlier with ctDNA than with conventional radiologic assessment or CA125 monitoring. These findings demonstrate that serial ctDNA testing could effectively monitor patients and detect minimal residual disease, facilitating early detection of disease progression and tailoring of adjuvant therapies for ovarian cancer treatment. Significance: In ovarian cancer, serial circulating tumor DNA testing is a highly predictive marker of patient survival, with a significantly improved recurrence detection lead time compared with conventional monitoring tools.
Teclistamab Induces Favorable Responses in Patients with Relapsed and Refractory Multiple Myeloma after Prior BCMA-Directed Therapy
Authors: Ariel F. Grajales-Cruz, Omar Castaneda, Doris K. Hansen, Mariola A Vazquez-Martinez, Brandon Blue, Sushmita Khadka, Hien Liu, Jose L. Ochoa-Bayona, Ciara Louise L. Freeman, Frederick L. Locke, Taiga Nishihori, Kenneth Shain, Rachid Baz, Melissa Alsina
Journal: Blood (2023)
A Completely Oral Regimen Including Oral Etoposide As Cytoreductive Chemotherapy Combined with All Trans Retinoic Acid and Oral Arsenic for Induction Therapy in Patients with High-Risk APL：Comparable to Intravenous Cytoreductive Therapy
Authors: Feifei Tang, Wen-Bing Duan, Xiao-Hong Liu, Sheng-Ye Lu, Xiao-Su Zhao, Ya-Zhen Qin, Jin-Song Jia, Jing Wang, Li-Zhong Gong, Qian Jiang, Zhao Ting, Hong-Xia Shi, Ying-Jun Chang, Xiao-Jun Huang, Hao Jiang
Journal: Blood (2023)
Validation of the Composite Complete Response (cCR) Definitions in the International Working Group (IWG) 2023 Criteria in Patients (Pts) with Higher-Risk Myelodysplastic Syndromes/Neoplasms (HR-MDS) Treated with Hypomethylating Agents (HMA) - a Large, Multicenter, Retrospective Analysis from the Validate Database
Authors: Jan Philipp Bewersdorf, Tariq Kewan, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Geoffrey L Uy, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Christine M. McMahon, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Maria L Amaya, Hayley Hawkins, Justin Grenet, Rory M. Shallis, Zhuoer Xie, Jaroslaw P. Maciejewski, David A Sallman, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood (2023)
NFκB Dysregulation in the Bone Marrow Niche Drives Epigenomic Reprogramming of Hematopoietic Stem Cells and Myeloid Bias
Authors: Jennifer J Chia, Apeksha Singh, Yu-Sheng Eason Lin, Tiffany Tran, Jennifer King, Dinesh S. Rao, Alexander Hoffmann
Journal: Blood (2023)
Endpoint Surrogacy in Chronic Lymphocytic Leukemia: A Pooled Analysis of the German CLL Study Group
Authors: Florian Simon, Rudy Ligtvoet, Sandra Robrecht, Paula Cramer, Nadine Kutsch, Moritz Furstenau, Valentin Goede, Julia Von Tresckow, Petra Langerbeins, Anna-Maria Fink, Henriette Huber, Eugen Tausch, Christof Schneider, Clemens-Martin Wendtner, Matthias Ritgen, Martin Dreyling, Lothar Müller, Lutz Jacobasch, Werner Heinz, Ursula Vehling-Kaiser, Liliya Sivcheva, Sebastian Böttcher, Peter Dreger, Thomas Illmer, Michael Gregor, Philipp Bernhard Staber, Stephan Stilgenbauer, Carsten Utoft Niemann, Arnon P. Kater, Kirsten Fischer, Barbara F. Eichhorst, Michael Hallek, Othman Al-Sawaf
Journal: Blood (2023)
Genetic Evolution from Chronic Myeloproliferative Neoplasms to Acute Myeloid Leukemia: An Analysis of Forty-Six Paired Samples
Authors: Hung Chang, Hsiao-Wen Kao, Ming-Chung Kuo, Jin-Hou Wu, Ying-Jung Huang, Ting-Yu Huang, Tung-Huei Lin, Lee-Yung Shih
Journal: Blood (2023)
Safety, Pharmacodynamic, and Anti-Tumor Activity of SL-172154 As Monotherapy and in Combination with Azacitidine (AZA) in Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) and Higher-Risk Myelodysplastic Syndromes/Neoplasms (HR-MDS) Patients (pts)
Authors: Naval Daver, Anthony Selwyn Stein, Dale Bixby, Wanxing Chai-Ho, Joshua F. Zeidner, Keri Maher, Don A. Stevens, Maximilian Stahl, Karen Yee, Emily K Curran, Sawa Ito, Andrew Sochacki, David A Sallman, Robert Hernandez, Simon Metenou, Bo Ma, Kazunobu Kato, Amer M. Zeidan
Journal: Blood (2023)
Flumatinib for Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia: An Open-Label, Multi-Center Study
Authors: Ziyu Wen, Ying Zhao, Guowei Li, YongZhong Su, FeiHeng Chen, HongFang Tao, ZhengJin Zheng, Wuqiang Lin, XiuLi Chen, Meili Meng, Lian Yu, LongTian Chen, JianQing Huang, Guocai Wu, Mengxia Zhao, Zhenfang Liu, Hongqian Zhu, Yirong Jiang, Qifa Liu, Xiaoli Liu, Na Xu
Journal: Blood (2023)
Multi-Omics Reveals Azacitidine Partially Restores Hematopoiesis-Supportive Functions in Mesenchymal Stromal Cells from Patients with Chronic Myelomonocytic Leukemia
Authors: Ruohao Xu, Suxia Geng, Lingji Zeng, Chengxin Deng, Xin Huang, Minming Li, Ping Wu, Peilong Lai, Jianyu Weng, Xin Du
Journal: Blood (2023)
Resistance Mechanisms Impacting Bispecific Antibody (BsAbs) and Chimeric Antigen Receptor (CAR) T-Cell Therapy Outcomes in Large B Cell Lymphoma (LBCL) Patients
Authors: Josu Iraola-Truchuelo, Gloria Iacoboni, Laura Palomo, Victor Navarro Garces, Josep Castellvi, Alba Mas, Lara Nonell, Luis A Mayor, Victoria Dourdil, Tomas Garcia Cerecedo, Oriana López Godino, Mario Sánchez-Salinas, Cecilia Carpio, Marta Crespo, Angel Serna, Alba Cabirta Touzón, Marc Bosch, Cristina García, Pere Barba, Francesc Bosch, Pau Abrisqueta Costa
Journal: Blood (2023)
HbF Inducing Eed Inhibitor Ftx-6058 Selectively and Reversibly Impacts Bone Marrow in Wild-Type Mice
Authors: Emily M Fitz, Allysa Allen, Lynn Edwards, Suchi Raghunathan, Briana Steward, David J Matson, Caroline V Sartain, Paul A Bruno, Jeffrey W Jacobs, Billy Stuart
Journal: Blood (2023)
Whole Genome and Transcriptome Sequencing of 21 Paired Chronic and Blast Phase CML Cases: Acquisition of Genomic Alterations, Changes in the Transcriptomic Profiles and Occurrence of B-Cell Receptor Rearrangements
Authors: Claudia Haferlach, Wencke Walter, Heiko Mueller, Sandra Huber, Constance Regina Baer, Stephan Hutter, Manja Meggendorfer, Gregor Hoermann, Wolfgang Kern, Torsten Haferlach
Journal: Blood (2023)
Rheological Characteristics of Elderly Individuals with Sickle Cell Disease Compared with an Adult Sickle Cell Population
Authors: Justin J Yoo, Jordan Zgodny, Britney Hernandez, Jawa Darazim, Ashwin P Patel, Fuad El Rassi, G. Karen Yu, Alka A Potdar, Vivien A. Sheehan
Journal: Blood (2023)
Outsmart™ IL-2/15, a Novel Cytokine Designed to Enhance ROR1-Specific CAR T Anti-Tumor Activity While Minimizing Treg Activation and Systemic Cytokine Exposure
Authors: Howell Moffett, Brian Weitzner, Thaddeus Davenport, Leah Tait, Tina Tan, Laura Baker, John Crowl, Willimark Obenza, Bradley Hammerson, Robin Kirkpatrick, Paul Sample, Lesley Jones, Erik Hermans, Robert Langan, Kevin Haworth, Scott Boyken, Aaron Foster, Marc Lajoie
Journal: Blood (2023)
A Multiomic Single-Cell Atlas of Human Myelopoiesis Reveals Cellular and Molecular Drivers of Immunomodulatory Drug-Induced Neutropenia
Authors: Christina Simoglou Karali, Simone Riva, Sally-Ann Clark, Sean Wen, Nikolaos Sousos, Eleni Louka, E. Ravza Gür, Nawshad Hayder, William E. Pierceall, Anjan Thakurta, Anita K. Gandhi, Patrick R Hagner, Jim Hughes, Adam J Mead
Journal: Blood (2023)
Ferroptosis Inhibition Generates TCF-1 + CAR-T Cells with Enhanced Persistence and Cytotoxicity
Authors: Shinpei Harada, Daigo Hashimoto, Yumika Saito, Toru Miyajima, Wenyu Li, Hajime Senjo, Zixuan Zhang, Ryo Kikuchi, Masahiro Chiba, Hiroyuki Ohigashi, Takahide Ara, Masao Nakagawa, Takanori Teshima
Journal: Blood (2023)
Real-World Evidence in the United States (US) of the Impact of Bridging Therapy Prior to Axicabtagene Ciloleucel (Axi-Cel) for the Treatment of Relapsed or Refractory Large B-Cell Lymphoma (R/R LBCL)
Authors: Michael Roderick Cook, Roni Shouval, Miguel-Angel Perales, Evandro Bezerra, Alex Niu, Saurabh Dahiya, Loretta J. Nastoupil, Caron A. Jacobson, L. Elizabeth Budde, Amanda L. Olson, Brent R. Logan, Zhen-Huan Hu, Hai-Lin Wang, Zhong-Cheng Luo, Jenny J. Kim, Harry W. Smith, Andrew Lee, Fang Sun, Marcelo Pasquini, Frederick L. Locke
Journal: Blood (2023)
Out-of-Pocket Costs and Financial Hardship Among Participants of the BMT CTN 1102 Study
Authors: Christopher T. Su, Wael Saber, Aasthaa Bansal, Li Li, Ryotaro Nakamura, Corey Cutler, Bart L. Scott, Lindsey R Sangaralingham, Viengneesee Thao, Joshua Roth, Winona Wright, Lotte Steuten, Deborah Mattila, Scott D Ramsey
Journal: Blood (2023)
Number Needed to Treat Analyses of Zanubrutinib in Relapsed/Refractory Chronic Lymphocytic Leukaemia
Authors: Asher Alban Chanan-Khan, Kirollos S. Hanna, Mei Xue, Marjan Massoudi, Mark Balk, Hossein ZivariPiran, Cecilia Duan, Keri Yang
Journal: Blood (2023)
Cluster Analysis Reveals Distinct Subgroups with Severe Pain in Sickle Cell Disease: A Cross-Sectional Study Using the Grndad Multi-Center Registry
Authors: Martha O Kenney, Samuel Wilson, Morgan Rosser, Sophie Lanzkron, Julie Kanter, Amma T. Owusu-Ansah, Alice J. Cohen, Deepa Manwani, Jane A. Little
Journal: Blood (2023)
Inflammatory Biomarkers and Outcomes in Multiple Myeloma Patients after CAR T-Cell Therapy
Authors: Darren Denjay Pan, Tarek H. Mouhieddine, Weijia Fu, Erin Moshier, Samir Parekh, Sundar Jagannath, Adriana C Rossi, Hearn Jay Cho, Joshua Richter, Larysa J Sanchez, Santiago Thibaud, Cesar Rodriguez, Shambavi Richard
Journal: Blood (2023)
Telehealth Serious Illness Care Program for Older Adults with Acute Myeloid Leukemia and Myelodysplastic Syndromes: A Single-Arm Pilot Study
Authors: Marissa Locastro, Soroush Mortaz-Hedjri, Ying Wang, Jason H. Mendler, Sally Norton, Rachelle Bernacki, Thomas Carroll, Heidi Klepin, Jane L. Liesveld, Eric J Huselton, Benzi Kluger, Kah Poh Loh
Journal: Blood (2023)
Hospitalists' Perspective of Inpatient Care for Patients with Sickle Cell Disease and Areas for Improvement
Authors: Alejandro Vera, Francis William Coyne, Regina Dennis, Kevin Fiscella, Areeba Kara, Robert LeGros, Matthew McIntosh, Lalita Movva, Jennifer Readlynn, Sharee Turpin, Reza Yousefi-Nooraie, Ashley Jenkins
Journal: Blood (2023)
Real-World Safety and Efficacy of Teclistamab for Patients with Heavily Pretreated Relapsed-Refractory Multiple Myeloma
Authors: Danai Dima, James A Davis, Nausheen Ahmed, Aishwarya Sannareddy, Hira Shaikh, Zahra Mahmoudjafari, Jack Khouri, Gurbakhash Kaur, Christopher Strouse, Jason Valent, Larry D. Anderson, Faiz Anwer, Al-Ola Abdallah, Hamza Hashmi
Journal: Blood (2023)
Single Cell Transcriptomics Reveal That HMGA1 Chromatin Regulators Drive Transcriptional Networks Involved in Megakaryocyte Expansion, Platelet Activation, and Interferon Signaling in <i>JAK2 V617F</i> Myeloproliferative Neoplasms
Authors: Zanshe Thompson, Li Z Luo, Liping Li, Bowen Wang, Jung-Hyun Kim, Hyunsung Woo, Bailey West, Anandi Krishnan, Leslie Cope, Alison R. Moliterno, Jerry L. Spivak, Linda Resar
Journal: Blood (2023)
Comprehensive Characterization of the Bone Marrow Microenvironment Transcriptional Remodeling in the Progression from MGUS to Smoldering and Multiple Myeloma
Authors: Itziar Cenzano, Miguel Cocera, Azari Bantan, Marta Larrayoz, Amaia Vilas-Zornoza, Patxi San-Martin, Paula Aguirre-Ruiz, Beñat Ariceta, Jin Ye, Diego Alignani, Aitziber Lopez, Aleksandra Kurowska, Fatimah AlSultan, Raghad Shuwaikan, Vincenzo Lagani, Jesper Tegner, Iñaki I. Martin Subero, Jose A. A Martinez-Climent, Xabier Agirre, Borja Saez-Ochoa, Bruno Paiva, Jesus San-Miguel, Mikel Hernaez, Isabel A Calvo, David Gomez-Cabrero, Felipe Prosper
Journal: Blood (2023)
Treatment Challenges in Acute Myeloid Leukemia in Lower-Middle-Income Countries: Navigating Intensity, Affordability, and Infections
Authors: Chitresh Yadav, Manoj Unni, Mobin Paul, Monisha Harimadhavan, Rema Ganapathy, Nikhil Krishna Haridas, Sheejamol V.S., Chitra Sreenaryanan, Rashmi Yawalkar, Ullas Mony, Neeraj Sidharthan
Journal: Blood (2023)
Interdigitating Dendritic Cell Sarcoma and Indeterminate Dendritic Cell Tumor: Patient Characteristics, Prognostic Factors, and Survival Outcomes for Rare Dendritic Cell Neoplasms
Authors: Tyler Fugere, Brad Fugere, Fnu Amisha, Jim Zhongning Chen, Akash Mukherjee, Mamatha Gaddam, Muthu Veeraputhiran, Cesar Giancarlo Gentille Sanchez
Journal: Blood (2023)
Interplay between Inflammatory Microenvironment and RUNX1-Mediated Transcriptomic Changes Drives Defective Hematopoiesis in Familial Platelet Disorder
Authors: Mona M.Hosseini, Trevor Enright, Adam S Duvall, Alex Chitsazan, Hsin-Yun Lin, Aysegul Ors, Brett Davis, Joseph Estabrook, Olga Nikolova, Jamie Lynn Diemer, Kathleen Craft, Erica Bresciani, Katherine R. Calvo, Matthew Merguerian, Marshall Horwitz, Sioban Keel, Lucy Godley, Lucio H. Castilla, Emek Demir, Hisham Mohammed, Paul Pu Liu, Anupriya Agarwal
Journal: Blood (2023)
Immune-Related Gene Expression Signatures Identify a Patient's Subset Achieving Durable Complete Response to Brentuximab Vedotin in Relapsed/Refractory Hodgkin Lymphoma
Authors: Paulina Nierychlewska, Maria Rosaria Sapienza, Alessandro Davini, Eugenia Montanari, Anna Vanazzi, Simonetta Viviani, Valentina Tabanelli, Roberto Massimo Lemoli, Corrado Tarella, Stefano Pileri, Enrico Derenzini
Journal: Blood (2023)
In Vivo Reprogramming of Adult Liver Sinusoidal Vascular Endothelial Cells into a Hematopoietic Stem and Progenitor Cell Niche
Authors: Tianxiao Han, Rajesh D. Gunage, Ran Jing, Alexandra F. Corbin, Kenny Zhi Ming Chen, Yang Tang, Olivia Stockard, Song Yang, Yi Zhou, George Q. Daley, Thorsten M. Schlaeger, Leonard I. Zon
Journal: Blood (2023)
Excellent Early and Major Molecular Responses Observed with Asciminib Treatment for CP-CML: Results from the ALLG CML13 Ascend-CML Study
Authors: David T Yeung, Naranie Shanmuganathan, John Reynolds, Susan Branford, Mannu Walia, Agnes S. M. Yong, Jake Shortt, Kate Burbury, Lynette C.Y. Chee, Nick Viiala, Ilona Cunningham, David M. Ross, Alwyn Bernard D'Souza, Matthew P.F. Wright, Rosemary Anne Harrup, Cecily Forsyth, Robin Filshie, Peter J. Browett, Steven W. Lane, Carolyn Grove, Andrew P Grigg, Timothy P Hughes, on Behalf Of The ALLG
Journal: Blood (2023)
Prognostic Value of Measurable Residual Disease in High-Risk Myelodysplastic Syndromes with Intensive Chemotherapy Treatment: Analysis of HOVON-SAKK Studies
Authors: Lok Lam Ngai, Coen R. Veenstra, Patrycja Gradowska, Angèle Kelder, Willemijn Scholten, Alexander N. Snel, Jesse M. Tettero, Costa Bachas, Dimitri Breems, Thomas Fischer, Bjorn T. Gjertsen, Laimonas Griškevičius, Gunnar Juliusson, Johan Maertens, Markus G. Manz, Thomas Pabst, Jakob Passweg, Kimmo Porkka, Canan Alhan, Theresia M. Westers, Peter J. M. Valk, David C. de Leeuw, Bob Lowenberg, Gert Ossenkoppele, Jacqueline Cloos, Arjan A. van de Loosdrecht
Journal: Blood (2023)
Network Meta-Analysis of Randomized Trials in Relapsed/Refractory Multiple Myeloma: Relative Efficacy for Patients Who Are Lenalidomide-Refractory
Authors: Efstathios Kastritis, Rebecca Harvey, Holly Cranmer, Martina Bianco, Elisabetta Fenu, Charles La Porte, Karthik Ramasamy
Journal: Blood (2023)
A Phase I/II Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of BTK Inhibitor HZ-a-018 in Adult Patients with Relapsed and/or Refractory Central Nervous System Lymphoma
Authors: Wenbin Li, Zhuang Kang, Feng Chen, Shenglan Li, Xianggui Yuan, Xi Chen, Wenbin Qian, Haiyan Yang, Miao Hu, Xinglu Zhou
Journal: Blood (2023)
<i>Ex Vivo</i> Mathematical Myeloma Advisor (EMMA) - a Clinical, Molecular, and Phenotypic Platform to Tailor Personalized Therapeutic Strategies for Multiple Myeloma
Authors: Rafael Renatino-Canevarolo, Maria Silva, Mark B Meads, Xiaohong Zhao, Alexandra Achille, David Noyes, Praneeth Reddy Sudalagunta, Raghunandan Reddy Alugubelli, Daniel Lastorino, Leticia Tordesillas, Miguel Gomez Fontela, Oliver Hampton, Daniel Abate-Daga, Kenneth H. Shain, Ariosto Siqueira Silva
Journal: Blood (2023)
Heterogeneity in Access and Toxicity Management of Commercially Available BCMA-Directed CAR-T and Bispecific T-Cell Engager Therapy Among the International Myeloma Community
Authors: Hamza Hassan, Mehmet K. Samur, Adam D. Cohen, Philippe Moreau, Paula Rodríguez Otero, Shaji Kunnathu Kumar, María Victoria Mateos, David Avigan, Adam S. Sperling, Omar Nadeem, Michael Hudecek, Carlos Fernández de Larrea, Joaquin Martínez-López, Maria Themeli, Kwee Yong, Jesus G. Berdeja, Ajai Chari, Pieter Sonneveld, Francesca Gay, Amrita Krishnan, Saad Z Usmani, Kenneth C. Anderson, Sundar Jagannath, Hermann Einsele, Nikhil C Munshi, Shonali Midha
Journal: Blood (2023)
Identification of 17 Distinct IDH1/IDH2 Mutations from Acute Myeloid Leukemia Peripheral Blood Using a Multiplex Real-Time PCR Closed Cartridge System
Authors: Edgar Baculi, Vineela Kadiyala, Long Tan, Bach Nguyen, Nhung Huynh, Tengyao Song, Gwo-Jen Day, Lin Yuan, Michael Bates, Huilin Wei
Journal: Blood (2023)
Explainable End-to-End Supervised Learning Identifies Myelodysplastic Neoplasms in Bone Marrow Smears
Authors: Jan-Niklas Eckardt, Tim Schmittmann, Freya Schulze, Sebastian Riechert, Martin M. K. Schneider, Lukas Reichel, Miriam Eva Helena Gediga, Katja Sockel, Anas Shekh Sulaiman, Ekaterina Balaian, Christoph Röllig, Frank P. Kroschinsky, Anne Marie Asemissen, Uwe Platzbecker, Christian Pohlkamp, Torsten Haferlach, Karsten Wendt, Martin Bornhäuser, Jan Moritz Middeke
Journal: Blood (2023)
Combination of Propranolol and a Novel CXCR4 Antagonist Burixafor (GPC-100) for Enhanced Hematopoietic Cell Mobilization
Authors: Devki D. Sukhtankar, Thomas Cayton, Piotr Zalicki, Junhee Choi, Seonggyeong Mun, Yoonjung Jo, Sujeong Kim, Ji Yeong Lee, Mi-Na Kim, Ashley Chin, Christian Ramos, Won-Ki Huh, Sohui Kim, Nina Caculitan, Jae-Yeon Jeong, Josephine M. Cardarelli
Journal: Blood (2023)
Age-Based Validation of the Advanced-Stage Hodgkin Lymphoma International Prognostic Index (A-HIPI) in a Real-World Danish Study: Suboptimal Performance in Older Patients
Authors: Rasmus Rask Kragh Jørgensen, Sandra Eloranta, Jacob Haaber Christensen, Martin Hutchings, Rasmus Bo Dahl-Soerensen, Peter Kamper, Andrew M Evens, Matthew J. Maurer, Susan K Parsons, Angie Mae Rodday, Jenica Upshaw, Tarec Christoffer Christoffer El-Galaly, Lasse Hjort Jakobsen
Journal: Blood (2023)