tbuckley/cabot-search huggingface dataset:
Comparing Acalabrutinib and Ibrutinib in the Real World: A Study of 2,509 Patients with Chronic Lymphocytic Leukemia
Authors: Lindsey E. Roeker, Maral DerSarkissian, Kellie J. Ryan, Yan Chen, Svea K. Wahlstrom, Shweta Hakre, Louise Yu, Helen Guo, Anthony R. Mato
Journal: Blood (2022)
Comparison of Vital Status and Cause-Specific Mortality after Hematopoietic Cell Transplantation between the Center for International Blood and Marrow Transplant Research and the California Cancer Registry: A Record-Linkage Analysis from 1991 to 2018
Authors: Bryan Valcarcel, Sara J. Schonfeld, Christa L. Meyer, Ann M Brunson, Julianne J.P. Cooley, Renata Abrahao, Ted Wun, Jeffery Auletta, Lori Muffly, Theresa H.M. Keegan, Lindsay M. Morton
Journal: Blood (2022)
Pharmacologic Inhibitors of STAT3 or BCL6 Transcriptional Function Sensitize Lymphoma Cells to the Novel PD-1 Cis-Targeted PD1-IL2v Immunocytokine in a Murine Model
Authors: Weiyuan Wang, Foster Burton, Sylvia Herter, Laura Codarri Deak, Christian Klein, David Frank
Journal: Blood (2022)
Molecular Characterization of Clinical Response and Relapse in Patients with <i>IDH1</i>m ND-AML Treated with Ivo+AZA in the AGILE Study
Authors: Hartmut Döhner, Dylan M. Marchione, Sung Choe, Pau Montesinos, Christian Recher, Susana Vives, Ewa Zarzycka, Jianxiang Wang, Claudio Cerchione, Michael Heuser, Rodrigo T. Calado, Andre C. Schuh, Su-Peng Yeh, Adolfo De La Fuente, Jianan Hui, Prapti Patel, Diego A. Gianolio, Scott R. Daigle, Courtney D. DiNardo, Stephane De Botton
Journal: Blood (2022)
The Decisive Role of Pronounced Hyperferritinemia for Diagnosis and Prognosis in the Spectrum of Hematological Disorders
Authors: Andres Vargas-España, Valerie Fuentes-Martin, Luis Arias-Espinosa, Oscar Manuel Fierro-Angulo, Mauricio Russ-Tolmos, Ariel de la Puente, Jose M Toledo, Alec Seidman-Sorsby, Adrian Soto Mota, Christianne Bourlon De Los Rios
Journal: Blood (2022)
Targeting PIP4K2 Lipid Kinases through Thz-P1-2 Reveals Vulnerabilities Related to Mitochondrial Homeostasis and Autophagy in Acute Leukemia
Authors: Keli Lima, Diego A Pereira-Martins, Lívia Bassani Lins de Miranda, Juan L Coelho-Silva, Giovana da Silva Leandro, Isabel Weinhäuser, Rita de Cassia Cavaglieri, Wellington F Silva, Aline Medeiros Leal, Ana Paula Alencar de Lima Lange, Elvira Deolinda Rodrigues Pereira Velloso, Emmanuel Griessinger, Jacobien R Hilberink, Gerwin A. Huls, Jan Jacob Schuringa, João Agostinho Machado-Neto, Eduardo M Rego
Journal: Blood (2022)
Interleukin-18 Secreting Autologous Anti-CD19 CAR T-Cells (huCART19-IL18) in Patients with Non-Hodgkin Lymphomas Relapsed or Refractory to Prior CAR T-Cell Therapy
Authors: Jakub Svoboda, James N. Gerson, Daniel J. Landsburg, Elise A. Chong, Stefan K. Barta, Sunita Dwivedy Nasta, Marco Ruella, Elizabeth O. Hexner, Amy Marshall, Rachel Leskowitz, Megan Four, Joanne Shea, Tina Matlawski, Amanda Cervini, Megan M. Davis, Mercy Gohil, John Scholler, Donald Hasenmayer, Juliana Rojas Amortegui, Andrea Brennan, Gabriela Plesa, Wei-Ting Hwang, David L. Porter, Joseph Fraietta, Stephen J. Schuster, Carl H. June
Journal: Blood (2022)
Long-Term Outcomes of Autologous Hematopoietic Cell Transplant of Multiple Myeloma: A 10 Year Follow up Study
Authors: Hussein Awada, Adel Hajj Ali, Muhammad Faizan Ali, Beth M. Faiman, Allison Winter, Sandra Mazzoni, Deepa Jagadeesh, Christy J. Samaras, Louis S. Williams, Craig S. Sauter, Willem J. van Heeckeren, Robert M. Dean, Brad Pohlman, Betty K. Hamilton, Brian T. Hill, Jason Valent, Ronald M. Sobecks, Matt Kalaycio, Jack Khouri, Faiz Anwer
Journal: Blood (2022)
Integrin Signaling Pathway Is Crucial for the Recently Divided Fraction of CLL Cells and Facilitates Cell Migration in a Disease Progressive Manner
Authors: Xiao J. Yan, Florencia Palacios, Shih-Shih Chen, Wentian Li, Joanna M. Rhodes, Jacqueline C. Barrientos, Steven L Allen, Jonathan E. Kolitz, Kanti R Rai, Nicholas Chiorazzi
Journal: Blood (2022)
Evolving Pattern Improves the IMWG 2/20/20 Classification for Patients with Smoldering Multiple Myeloma
Authors: Luis Gerardo Rodríguez-Lobato, Anna de Daniel i Bisbe, Natalia Tovar, Raquel Jiménez-Segura, M. Teresa Cibeira, David F. Moreno, Aina Oliver-Caldes, Alexandra Martínez-Roca, Ester Lozano, Joan Bladé Creixenti, Laura Rosinol Dachs, Carlos Fernandez de Larrea
Journal: Blood (2022)
State Variation in Squamous Cell Carcinoma of the Anus Incidence and Mortality, and Association With HIV/AIDS and Smoking in the United States
Authors: Haluk Damgacioglu, Yueh-Yun Lin, Ana Patricia Ortiz, Chi-Fang Wu, Zahed Shahmoradi, Shiang Shiuan Shyu, Ruosha Li, Alan G. Nyitray, Keith Sigel, Gary M. Clifford, Naomi Jay, Vivian Colon Lopez, Gregory M. Barnell, Elizabeth Y. Chiao, Elizabeth A. Stier, Karen J. Ortiz-Ortiz, Jeslie M. Ramos-Cartagena, Kalyani Sonawane, Ashish A. Deshmukh
Journal: Journal of Clinical Oncology (2022)

PURPOSE Squamous cell carcinoma of the anus (SCCA) incidence and mortality rates are rising in the United States. Understanding state-level incidence and mortality patterns and associations with smoking and AIDS prevalence (key risk factors) could help unravel disparities and provide etiologic clues. METHODS Using the US Cancer Statistics and the National Center for Health Statistics data sets, we estimated state-level SCCA incidence and mortality rates. Rate ratios (RRs) were calculated to compare incidence and mortality in 2014-2018 versus 2001-2005. The correlations between SCCA incidence with current smoking (from the Behavioral Risk Factor Surveillance System) and AIDS (from the HIV Surveillance system) prevalence were evaluated using Spearman's rank correlation coefficient. RESULTS Nationally, SCCA incidence and mortality rates (per 100,000) increased among men (incidence, 2.29-3.36, mortality, 0.46-0.74) and women (incidence, 3.88-6.30, mortality, 0.65-1.02) age ≥ 50 years, but decreased among men age &lt; 50 years and were stable among similar-aged women. In state-level analysis, a marked increase in incidence (≥ 1.5-fold for men and ≥ two-fold for women) and mortality (≥ two-fold) for persons age ≥ 50 years was largely concentrated in the Midwestern and Southeastern states. State-level SCCA incidence rates in recent years (2014-2018) among men were correlated ( r = 0.47, P &lt; .001) with state-level AIDS prevalence patterns. For women, a correlation was observed between state-level SCCA incidence rates and smoking prevalence ( r = 0.49, P &lt; .001). CONCLUSION During 2001-2005 to 2014-2018, SCCA incidence and mortality nearly doubled among men and women age ≥ 50 years living in Midwest and Southeast. State variation in AIDS and smoking patterns may explain variation in SCCA incidence. Improved and targeted prevention is needed to combat the rise in SCCA incidence and mitigate magnifying geographic disparities. [Media: see text]
Persistance or Reappearance of Serum Monoclonal Protein Detected By Mass Spectrometry Is a Major Prognostic Factor in Patients with Newly Diagnosed Multiple Myeloma
Authors: Jean-Sébastien Claveau, David L Murray, Angela Dispenzieri, Prashant Kapoor, Moritz Binder, Francis K. Buadi, David Dingli, Amie Fonder, Morie A. Gertz, Wilson I. Gonsalves, Suzanne R. Hayman, Miriam A. Hobbs, Yi L. Hwa, Taxiarchis Kourelis, Martha Q. Lacy, Nelson Leung, Yi Lin, Rahma M Warsame, Robert A. Kyle, S. Vincent Rajkumar, Shaji K Kumar
Journal: Blood (2022)
TPL2, a New Prognostic Factor and a Potential Therapeutic Target in ABC-DLBCL
Authors: Kota Yoshifuji, Yotaro Motomura, Makiko Saito, Ayako Nogami, Genji Kawade, Shiori Watabe, Kouhei Yamamoto, Takehiko Mori, Toshikage Nagao
Journal: Blood (2022)
Antibody Response to COVID-19 mRNA Vaccine in Patients with Multiple Myeloma and Waldenstrom's Macroglobulinemia after Primary Immunization and Booster: Reactivity to the Sars-Cov-2 WT Virus, Delta and Omicron Variants
Authors: Evangelos Terpos, Margherita Rosati, Jenifer Bear, Robert Burns, Ioannis Ntanasis-Stathopoulos, Santhi Devasundaram, Maria Gavriatopoulou, Efstathios Kastritis, Meletios-Athanasios Dimopoulos, George N Pavlakis, Barbara K Felber
Journal: Blood (2022)
Iron Deficiency Is Commonly Observed in Female Multiple Sclerosis (MS) Patients with Relapsed/Refractory or Primary Progressive Disease Referred for Biological Therapies
Authors: Sarah Patel, Rajat Thawani, Thomas G. Deloughery, Vijayshree Yadav, Francisco Hernandez-Ilizaliturri, Merav Sendowski
Journal: Blood (2022)
Defining Ferritin Clinical Decision Limits to Improve Diagnosis and Treatment of Iron Deficiency: A Modified Delphi Study
Authors: Kanza Naveed, Nicola Goldberg, Eliane Shore, Arti Dhoot, Denise Gabrielson, Zahra Goodarzi, Yulia Lin, Menaka Pai, Natasha A. Pardy, Sue Robinson, Roseann Andreou, Manish Sood, Victoria Price, Ashley Verduyn, Michelle L. Parker, Michael Fralick, Daniel Beriault, Michelle Sholzberg
Journal: Blood (2022)
Intracellular Iron Overload Induces Metabolic Switching in Active Hematopoietic Stem Cells in Beta-Thalassemia
Authors: Annamaria Aprile, Silvia Sighinolfi, Laura Cassina, Mariacarla Panzeri, Mariangela Storto, Stefano Beretta, Ivan Merelli, Alessandra Boletta, Giuliana Ferrari
Journal: Blood (2022)
Association of Hypometilating Agents (HMA) + Venetoclax (VEN) in the Treatment of Myeloproliferative Neoplasms in Blastic Phase (MPN-BP) and Acute Leukemias Evolved from Myelodysplastic Syndromes (AML-MDS) Already Treated with Azacytidine
Authors: Roberto Latagliata, Gianluca Cristiano, Dorela Lama, Susanna Fenu, Lorenzo Rizzo, Benedetta Cambò, Simone Zoletto, Francesca Spirito, Fabrizio Cavalca, Daniele Cattaneo, Natalia Cenfra, Giulia De Luca, Beatrice Esposito Vangone, Ambra Di Veroli, Raffaele Palmieri, Mario Annunziata, Olga Mulas, Elisabetta Abruzzese, Alfredo Molteni, Monica Piedimonte, Ida Carmosino, Prassede Salutari, Annalisa Biagi, Monica Bocchia, Michelina Santopietro, Gianni Binotto, Alessandra Iurlo, Monica Crugnola, Marta Riva, Anna Lina Piccioni, Elena Maria Elli, Antonio Curti, Antonella Poloni
Journal: Blood (2022)
Evaluating the Impact of Lab-Based Eligibility Criteria By Race/Ethnicity in Frontline Clinical Trials for Diffuse Large B-Cell Lymphoma (DLBCL): A LEO Cohort Analysis
Authors: Arushi Khurana, Raphael Mwangi, Loretta J. Nastoupil, Patrick M. Reagan, Umar Farooq, Jason T. Romancik, Timothy J. McDonnell, Shaun M Riska, Izidore S. Lossos, Brad S. Kahl, Peter Martin, Thomas E. Witzig, James R. Cerhan, Christopher R. Flowers, Matthew J. Maurer, Grzegorz S. Nowakowski
Journal: Blood (2022)
Reduction in Endothelial Adhesion of Red Blood Cells Under Crizanlizumab: Assessment of Standardized Microfluidic Platform in Sickle Cell Disease Population
Authors: Chiara Federici, Erdem Kucukal, Seniye Sertel, Gabrielle Combs, Karamoja Monchamp, Aaron Wolfe, Lalitha Nayak, Andreas Bruederle, John Zak, Umut A. Gurkan
Journal: Blood (2022)
Naïve T Cell-Depleted Hematopoietic Graft Combined with Solid Organ Transplantation As Strategy to Induce Tolerance By Transient Mixed Chimerism
Authors: Antonio Perez, María Ovidia López, Rocío González-Sacristán, Mercedes Gasior, Antonio Marcos, Raquel De Paz Arias, José María Alonso, Carmen Mestre-Durán, Karima Al-Akioui, Cristina Ferreras, Antonio Balas, Jose Luis Vicario, Carlos Solano, Belén Estébanez, Esther Ramos-Boluda, Carlos Jiménez, Francisco Hernández-Oliveros
Journal: Blood (2022)
Retrospective Lineage Tracing of Pediatric Acute Myeloid Leukemia Using Single-Cell Whole Genome Sequencing
Authors: Eline J.M. Bertrums, Sjors Middelkamp, Inge M. van der Werf, Freek Manders, Arianne M. Brandsma, Niels M. Groenen, Mark Verheul, Markus J. van Roosmalen, C. Michel Zwaan, Marry M. van den Heuvel-Eibrink, Bianca F. Goemans, Ruben Van Boxtel
Journal: Blood (2022)
Phase I Study of the LSD1 Inhibitor Tranylcypromine (TCP) in Combination with All-<i>Trans</i> Retinoic Acid (ATRA) and Low-Dose Cytarabine (LDAC) in Elderly, Medically Non-Fit Patients with AML or High-Risk MDS (TRANSATRA trial)
Authors: Michael Lübbert, Claudia Schmoor, Tobias Berg, Michael Kruszewski, Marcus Matthias Schittenhelm, Katharina Götze, Caroline Pabst, Andrea Kündgen, Tobias Ma, Anna Frey, Kevin Moschallski, Usama-Ur Rehman, Johannes Jung, Justus Duyster, Manfred Jung, Roland Schüle, Ralph Wäsch, Olga Grishina
Journal: Blood (2022)
Haemogenic Gastruloids Recapitulate Developmental Haematopoiesis and Provide an Ontogeny-Relevant Context to Dissect the Origins of Infant Leukemia
Authors: Denise Ragusa, Chun-Wai Suen, Gabriel Torregrosa, Liza Dijkhuis, Connor Byrne, Tina Balayo, Andrea Tavosanis, Jozef Durko, Kristen Place, Ana Filipa Domingues, Kamil Kranc, Jordi Garcia-Ojalvo, Alfonso Martinez Arias, Cristina Pina
Journal: Blood (2022)
Platelets Bind Senescent Red Blood Cells and Mediate Their Clearance from the Circulation
Authors: Brendan J. McMorran, Dian C Ningtyas, Florentina Leitner, Kiran Javed, Megan Sawbridge, Sarah M Hicks, Yee Lin Thong, Jiwon Lee, Melanie Rug, Philip Y. Choi, Lucy Coupland, Elizabeth E. Gardiner
Journal: Blood (2022)
Preclinical Validation of EZH2 and HDAC I Dual Inhibition As a Potent Therapy for Refractory Myeloid Leukemia Associated with Down Syndrome
Authors: Kader Cicek, Joshua R. Faust, Meredith Tavenner, E. Anders Kolb, Sonali P. Barwe, Anilkumar Gopalakrishnapillai
Journal: Blood (2022)
Pegcetacoplan Corrects Hyperbilirubinemia in Both Untreated Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) and in Patients with PNH Who Previously Received Eculizumab
Authors: David J. Araten, Michael Yeh, Mohammed Al-Adhami, Regina Horneff, Federico Grossi
Journal: Blood (2022)
LP-118, a Selective Bcl-2 Inhibitor with Tuned Bcl-Xl Activity, Causes Myeloid Differentiation and Cell Death in Acute Myeloid Leukemia (AML)
Authors: Kristin L Koenig, Colin Brame, Steven Sher, Larry Beaver, Casey B. Cempre, Katie Williams, Matthew Purcell, Bonnie Harrington, Yi Chen, Felai Tan, Stephen P. Anthony, Yu Chen, Yue Shen, John C. Byrd, Rosa Lapalombella
Journal: Blood (2022)
Efficacy and Safety of Avatrombopag in Combination with Immunosuppressive Therapy in Treatment-Naïve and Relapsed/Refractory Severe Aplastic Anaemia - the Diaamond-Ava-First and Diaamond-Ava-Next Bayesian Optimal Phase II Trials
Authors: Zoe McQuilten, Lucy C Fox, Vanessa Fox, Stephane Heritier, Tracey J Batt, Piers Blombery, Jennifer Curnow, Alisa Higgins, Devendra Hiwase, Robin J Filshie, Frank Firkin, Paul Lacaze, Kylie D Mason, Tony Mills, Sushrut S. Patil, Dominic Pepperell, William S Stevenson, Jeffrey Szer, Neil Waters, Kate Wilson, Stephen B Ting, Erica M. Wood
Journal: Blood (2022)
JAK/Rock Inhibitor TQ05105 for Glucocorticoid-Refractory or -Dependent Chronic Graft-Versus-Host Disease：Preliminary Analysis Results of a Phase 1b/2 Study
Authors: Yanmin Zhao, Lifan Tu, Yishan Ye, Yi Luo, Jimin Shi, Jian Yu, Yi Yu, Fankai Meng, Tao Wang, He Huang
Journal: Blood (2022)
Incidence of Second Primary Malignancies (SPMs) in Patients in the US with Triple-Class-Exposed (TCE) Relapsed or Refractory Multiple Myeloma (RRMM)
Authors: Wenzhen Ge, Alexi Archambault, Thomas E. Delea, Karen Rodriguez Lorenc, James Harnett, Aaron Moynahan, Derek Weycker, Yariv Houvras, Glenn S. Kroog, Ning Wu, Christian Hampp, Qiufei Ma
Journal: Blood (2022)
Establishing Immunocompetent Leukemia Models to Investigate the Impact of CAR T Cells on the Immune Microenvironment and Bone Marrow Niche
Authors: Sarah E. Moore, Jaquelyn T. Zoine, Jeremy Chase Crawford, Deanna Langfitt, Juan M. Barajas, Sherif Abdelhamed, Ilaria Iacobucci, Dalia Haydar, Giedre Krenciute, Charles G. Mullighan, Jeffery M. Klco, Stephen Gottschalk, Paul G. Thomas, Mireya Paulina Velasquez
Journal: Blood (2022)
Characteristics and Outcomes for Adult Patients with T-Lymphoblastic Leukemia/Lymphoma (T-ALL/LBL): A Retrospective Study
Authors: Julian Hardy McLain, Madeline Macdonald, Matthew Juarez, Han Tun, Upama Giri, Maria E. Vergara-Lluri, Imran Siddiqi, Zaw Win Myint
Journal: Blood (2022)
A Phase 2 Randomized Study Comparing Venetoclax and Azacitidine to Conventional Induction Chemotherapy for Newly Diagnosed Fit Adults with Acute Myeloid Leukemia
Authors: Amir T. Fathi, Geoffrey G Fell, Areej El-Jawahri, Alexander E. Perl, Brian A. Jonas, Ajoy L. Dias, Alice S. Mims, Uma Borate, Brittany Knick Ragon, Michael R. Grunwald, Mary Linton B. Peters, Timothy A. Graubert, Philip C. Amrein, Hanno R. Hock, Andrew M. Brunner, Gabriela S. Hobbs, Rupa Narayan, Donna S. Neuberg, Ibrahim Aldoss
Journal: Blood (2022)
KLRG1 Depletion Is a Novel Therapeutic Strategy for Patients with Mature T and NK/T-Cell Lymphomas
Authors: Bimarzhan Assatova, Christopher Trevisani, Robert Willim, Jessica Duffy, Abner Louissaint, Won-Seog Kim, David J Feith, Thomas Loughran, Foster Powers, Elizabeth A Morgan, Lei Yang, Brandy Pinckney, Garrett Haskett, Matthew J Cotton, Andrew Crabbe, Jessica Beth Ziemba, Ian Brain, Tayla B. Heavican-Foral, Nora Scanlan, Gail Newton, Jaehyuk Choi, Jeffrey A Barnes, Patrick Connor Johnson, Eric D Jacobsen, Steven Greenberg, David M. Weinstock, Salvia Jain
Journal: Blood (2022)
<i>In</i>-Class Transition (<i>i</i>CT) from Parenteral Bortezomib to Oral Ixazomib Therapy in Newly Diagnosed Multiple Myeloma (NDMM) Patients from the Community-Based US MM-6 Study: Subgroup Analyses of the Fully Accrued Dataset in Patients Aged &amp;lt;75 and ≥75 Years
Authors: Ruemu E. Birhiray, Robert M. Rifkin, Christopher A. Yasenchak, January Fields-Meehan, Roger M. Lyons, Ramalingham Ratnasabapathy, Kimberly Bogard, Kim Tran, Dasha Cherepanov, Stephen J. Noga, Saulius K. Girnius, Stephen J. Noga
Journal: Blood (2022)
Rituximab As an Effective Salvage Therapy in Pretreated Hairy Cell Leukemia Patients: The Bologna Experience
Authors: Alessandro Broccoli, Lisa Argnani, Laura Nanni, Gianmarco Bagnato, Matteo Carella, Beatrice Casadei, Paolo Elia Coppola, Gabriele Gugliotta, Ginevra Lolli, Marianna Gentilini, Alice Morigi, Cinzia Pellegrini, Vittorio Stefoni, Pier Luigi Zinzani
Journal: Blood (2022)
Itacitinib and Corticosteroids As Initial Treatment for Chronic Graft-Versus-Host Disease: Phase 1/2 Results from Gravitas-309
Authors: Annie Im, Daniel Wolff, Corey Cutler, Robert Zeiser, Nirav N. Shah, Ming Tony Tan, Jaime Sanz, Haris Ali, Giuseppe Milone, Arjun D. Law, Domenico Russo, Eva-Maria Wagner, Olga Ivanova, Kevin Hou, Maureen Bleam, Rodica Morariu-Zamfir, Steven Z Pavletic
Journal: Blood (2022)
Lipophagy As a Mechanism of Resistance in T-ALL Following Energetic Crisis Induced By Oxphos/MCT1 Blockade: Strategies to Eradicate Residual Disease
Authors: Natalia Baran, Shraddha Patel, Cassandra L Ramage, Alessia Lodi, Jose Enriquez Ortiz, Yogesh Dhungana, Meghan Collins, Anna Skwarska, Connie Weng, Kala Hayes, Zhihong Zeng, Laurie Cooper, Richard Eric Davis, Gheath Alatrash, Joseph R Marszalek, Jiyang Yu, Pratip K Bhattacharya, Stefano Tiziani, Marina Konopleva
Journal: Blood (2022)
Avatrombopag Treatment Response in Patients with Immune Thrombocytopenia: A Real-World Evidence Study
Authors: Abiola Oladapo, Scott Kolodny, Michael Vredenburg, Brian Jamieson, Elyse Swallow, Debbie Goldschmidt, Miriam L. Zichlin, Mikhail Davidson, Louise Yu, John Yee
Journal: Blood (2022)
A Population Pharmacokinetic (PopPK) Model to Characterize Efanesoctocog Alfa (BIVV001) Factor VIII (FVIII) Activity Levels in Patients with Severe Hemophilia A
Authors: Pratik Bhagunde, Qiang Lu, Marek Demissie, Annemieke Willemze, Suresh Katragadda
Journal: Blood (2022)
Short-Term Follow-up of Blinatumomab in Children with B-Cell Precursor Acute Lymphoblastic Leukemia：Study of a Single Center from China
Authors: Wenyu Yang, Xiaolan Li, Li-Peng Liu, Yang Wan, Tianfeng Liu, Bei-bei Zhao, Min Ruan, Benquan Qi, Xia Chen, Fang Liu, Yuanyuan Ren, Li Zhang, Yao Zou, Yumei Chen, Xiaojuan Chen, Ye Guo, Xiaofan Zhu
Journal: Blood (2022)
A Phase 1b Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of an Investigational Microbiome Therapeutic, SER-155, in Adults Undergoing Hematopoietic Stem Cell Transplantation
Authors: Doris M Ponce, Jonathan U Peled, Bindu Tejura, Christopher Ford, Marcel R M van den Brink, Mary Jane Lombardo, Satyajit Kosuri, Nandita Khera, Zachariah Defilipp, Lisa von Moltke
Journal: Blood (2022)
Effects of LSD1 Inhibition with Img-7289 on the Leukemia Initiating Cell Population with Induction of Differentiation and Cell Death in Pediatric Relapsed/Refractory AML
Authors: Jaclyn Rosenzweig, Diego Ferreira Coutinho, Matthew Long, Katie Souto, Glorymar Ibanez Sanchez, Raina Fishkin, Kristina Guillan, Armaan Siddiquee, Paul Calder, Daoqi You, Andrew L. Kung, Filemon Dela Cruz
Journal: Blood (2022)
Impact of Coronavirus (COVID-19) Pandemic on Maintenance Therapy for Follicular Lymphoma (FL) and Mantle Cell Lymphoma (MCL)
Authors: Angel Serna, Angela Sanchez, Laia Lopez, Juan-Manuel Sancho, Eva Gonzalez Barca, Alberto Lopez-Garcia, Raul Cordoba, Adolfo Jesús Sáez Marín, Ana Isabel Jiminez Ubieto, Ainara Ferrero, Tomas García, Alba Cabirta, M Moraima Jimenez, Lucia Martin, Marta Julia, Sabela Bobillo, Ana Marin-Niebla, Francesc Bosch, Pau Abrisqueta
Journal: Blood (2022)
Evolutionary Portrait of Adult Core-Binding Factor Leukemia Patients Treated with a Continuation Therapy with Midostaurin: Preliminary Results
Authors: Roberto Cairoli, Arianna Gatti, Giovanni Grillo, Monica Fumagalli, Mauro Krampera, Patrizia Zappasodi, Erika Borlenghi, Elisabetta Todisco, Marta Ubezio, Massimo Bernardi, Alfredo Molteni, Claudia Basilico, Mauro Turrini, Rosa Greco, Valentina Mancini, Marta Riva, Beatrice De Marco, Marta Rachele Stefanucci, Bruno Brando, Silvio Marco Veronese, Alessandro Beghini
Journal: Blood (2022)
Mutation Spectrum, Characteristics and Impact of Mutation Profiling on Prognosis, Outcome and Treatment Responses in Patients (pts) with Mantle Cell Lymphoma
Authors: Preetesh Jain, Chi Young Ok, Ahmed Fetooh, Rashmi Kanagal-Shamanna, Fatima Zahra Jelloul, Holly Hill, Kristen Floyd, Sanam Loghavi, Zhuang Zuo, C. Cameron Yin, Mark Routbort, Guilin Tang, Sairah Ahmed, Luis Enrique Malpica Castillo, Asiya Siddiqui, Wendy Chen, Onyeka Oriabure, Maria Badillo, Raphael E Steiner, Swaminathan P. Iyer, Hun Ju Lee, Rajyalakshmi Luthra, Francisco Vega, Christopher R. Flowers, Jeffrey Medeiros, Michael L. Wang, Keyur P. Patel, Nathan H. Fowler, Ranjit Nair
Journal: Blood (2022)
Can We Identify Individuals at Risk to Develop Multiple Myeloma? a Machine Learning Based Predictive Model
Authors: Moshe Mittelman, Howard S. Oster, Yatir Ben Shlomo, Ariel Israel, Osnat Jarchowcky Dolberg, Samah Hayek, Michael Leshchinsky, Eldad Kepten, Ran Balicer, Galit Shaham
Journal: Blood (2022)
CAR-T Cell Infusion Results in Activation of CD160+/NKG2D+/CCL5+ Non-CAR CD8+ Cytotoxic 'Bystander' T Cells in Both Non-Human Primates (NHP) and Patients Receiving B-Cell-Directed CAR-Ts
Authors: Ulrike Gerdemann, James Kaminski, Ryan A Fleming, Victor Tkachev, Francesca Alvarez Calderon, Connor McGuckin, Xianliang Rui, Jennifer Lane, Alex K. Shalek, Leslie Kean
Journal: Blood (2022)
Preliminary Results from a Phase 2 Open-Label, Multicenter, Dose Optimization Clinical Study of the Safety, Tolerability, and Pharmacokinetic (PK) and Pharmacodynamic (PD) Profiles of Cfi-400945 As a Single Agent or in Combination with Azacitidine or Decitabine in Patients with Acute Myeloid Leukemia, Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia (TWT-202)
Authors: Brian A. Jonas, Karen Yee, Paul B. Koller, Joseph Brandwein, Alice S. Mims, Glenn C. Michelson, Linh Nguyen, Mark R Bray, Emily L Roberts-Thomson, Gautam Borthakur
Journal: Blood (2022)
High-Throughput Screening to Elucidate In Vivo Oncogenicity of Loss-of-Function Alterations in Lymphoid Malignancies
Authors: Kentaro Yamaguchi, Junji Koya, Kota Mizuno, Kota Yoshifuji, Yuta Ito, Mitsuhiro Yuasa, Yuki Saito, Mariko Tabata, Sumito Shingaki, Yasunori Kogure, Kazutaka Nakashima, Koichi Ohshima, Keisuke Kataoka
Journal: Blood (2022)
Baseline Liver Elastography Does Not Predict Risks of Hepato-Toxicity to Reduced Dose Inotuzumab Therapy Combined with Minihcvd in B-Cell Acute Lymphoblastic Leukemia
Authors: Jayastu Senapati, Nicholas Short, Nitin Jain, Farhad Ravandi, Tharakeswara K. Bathala, Aram Bidikian, Fadi Haddad, Patrice Nasnas, Naval Daver, Tapan M. Kadia, Rebecca Garris, Monica Kwari, Hagop Kantarjian, Elias Jabbour
Journal: Blood (2022)