tbuckley/cabot-search huggingface dataset:
Hormone replacement therapy
Authors: J. C Stevenson
Journal: BMJ (2002)

<h3>Abstract</h3> <h3>Objective</h3> To determine if the problem list (health conditions) in primary care electronic medical records (EMRs) accurately reflects the conditions for which chronic medications are prescribed in the EMR. <h3>Design</h3> A retrospective analysis of EMR data. <h3>Setting</h3> Eighteen primary care clinics across rural and urban Manitoba using the Accuro EMR. <h3>Participants</h3> Data from the EMRs of active patients seen in an 18-month period (December 18, 2011, to June 18, 2013, or December 3, 2012, to June 3, 2014) were used. <h3>Main outcome measures</h3> The likelihood of documentation in the EMR problem list of those specific chronic diseases for which drug prescriptions were documented in the EMR. Regression modeling was performed to determine the effect of clinic patient load and remuneration type on the completeness of EMR problem lists. <h3>Results</h3> Overall problem-list completeness was low but was highest for diabetes and lowest for insomnia. Fee-for-service clinics generally had lower problem-list completeness than salaried clinics did for all prescription medications examined. Panel size did not affect problem-list completeness rates. <h3>Conclusion</h3> The low EMR problem-list completeness suggests that this field is not reliable for use in quality improvement initiatives or research until higher reliability has been demonstrated. Further research is recommended to explore the reasons for the poor quality and to support improvement efforts.
From the Health Care Financing Administration and the US Public Health Service
Authors: Philip R. Lee
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Experimental Colon Cancer in the Absence of Intestinal Contents in Sprague-Dawley Rats&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;
Authors: Rubio, C. A., Nylander, G., Santos, M.
Journal: JNCI Journal of the National Cancer Institute (1980)

Journal Article Experimental Colon Cancer in the Absence of Intestinal Contents in Sprague-Dawley Rats Get access C. A. Rubio, C. A. Rubio 3Department of Pathology, Karolinska Sjukhuset, S-104 01 Stockholm 60, Sweden. Search for other works by this author on: Oxford Academic PubMed Google Scholar G. Nylander, G. Nylander 4Department of Surgery, Karolinska Sjukhuset. Search for other works by this author on: Oxford Academic PubMed Google Scholar M. Santos M. Santos 4Department of Surgery, Karolinska Sjukhuset. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 64, Issue 3, March 1980, Pages 569–572, https://doi.org/10.1093/jnci/64.3.569 Published: 01 March 1980 Article history Received: 27 March 1979 Accepted: 06 August 1979 Published: 01 March 1980
Trends in Strength Training—United States, 1998-2004
Journal: JAMA (2006)

Strength training is physical activity intended to increase muscle strength and mass. Adults who engage in strength training are less likely to experience loss of muscle mass, functional decline, and fall-related injuries than adults who do not strength train. Studies on strength-training interventions have indicated that inactive older adults who begin regular strength training achieve substantial strength gains within a few months. Because certain health benefits are linked to strength training, a national health objective for 2010 is to increase to 30% the proportion of adults who perform physical activities that enhance and maintain muscular strength and endurance on > or =2 days per week (objective 22-4). This objective is also recommended by the American College of Sports Medicine. CDC analyzed 1998-2004 data from the National Health Interview Survey (NHIS) to determine the annual prevalence of strength training among U.S. adults by age group and race/ethnicity. This report describes the results of that analysis, which demonstrated that although the national prevalence of strength training for U.S. adults increased slightly during 1998-2004, only 21.9% of men and 17.5% of women (age adjusted) in 2004 reported strength training two or more times per week. This is substantially lower than the national 2010 objective of 30% and underscores the need for additional programs to increase strength training among adults.
ATRIAL NATRIURETIC PEPTIDE LEVELS IN TREATED CONGESTIVE HEART FAILURE
Authors: Yoichi Katoh, Toshiro Kurosawa, Sadao Takeda, Shingo Kurokawa, Hisato Sakamotom, Fumiaki Marumo, Ryuichi Kikawada, DonaldR.J. Singer, AngelaC. Shore, NirmalaD. Markandu, MartinG. Buckley, GrahamA. Macgregor
Journal: The Lancet (1986)
Femoral Neuropathy and Anticoagulant Therapy
Authors: Vasant P. Dhopesh
Journal: JAMA (1981)

<h3>To the Editor.—</h3> There is almost an 8% rate of hemorrhagic complications with long-term anticoagulant therapy.<sup>1</sup>Femoral neuropathy owing to retroperitoneal iliac hematoma is well known.<sup>2,3</sup>The purpose of this communication is to remind the physician of this complication and to question the treatment of surgical evacuation of the hematoma. The clinical picture is stereotyped. Typically, the patient experiences sudden, excruciating pain in the inguinal and hip area, radiating to the anterior section of the thigh. This is followed by weakness of the quadriceps muscle and loss of a knee-jerk response. However, the cases are almost always initially misdiagnosed. Some of the common misdiagnoses are diverticulitis, appendicitis, hip disease, and meralgia paresthetica. Patients sometimes undergo a barium enema examination, an intravenous pyelogram, or a myelogram. Diagnosis is usually delayed until there is a substantial drop in the hemoglobin level, the patient goes into shock, or a swelling with
INTERNATIONAL CATALOGUE OF SCIENTIFIC LITERATURE.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Continuing Medical Education
Journal: JAMA (1972)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Benign intracranial hypertension.
Authors: Stilianos E. Kountakis
Journal: BMJ (1970)

Although antecedent factors are occasionally implication, most cases of benign intracranial hypertension are idiopathic and occur in young adult women who otherwise appear healthy. The natural course is usually one of spontaneous recovery, although medical intervention may accelerate improvement. Computerized tomographic scanning is the procedure of choice for excluding more ominous conditions, such as brain tumors. The most serious complication of this syndrome is visual loss and in these patients the disease is not "benign."
Bronchogenic Carcinoma
Authors: Philip Rubin
Journal: JAMA (1966)

Carcinoma the lung is the number one killer of men who die of malignant disease. According to the American Cancer Society (personal communication, Aug 5, 1965), it accounted for 43,568 deaths in 1963, of which 36,980 were in men. Its peak incidence is in men 50 to 60 years of age and more deaths are due to lung cancer than to all other respiratory diseases. The increase in the number of lung cancers is real and rising (Fig 1). It is not simply due to better records or earlier diagnoses. This state of affairs is reaching alarming proportions and has triggered off extensive epidemiologic and laboratory studies. The facts clearly implicate environmental factors rather than hereditary or individual characteristics as the cause of lung cancer. The knowledge that cancer and cigarette smoking are related is generally recognized. Doll<sup>1</sup>states that, in the absence of smoking, the total male mortality
Injection Practices Among Nurses—Valcea, Romania, 1998
Journal: JAMA (2001)

In the early 1990s, human immunodeficiency virus (HIV) infection associated with possible reuse of syringes and needles was reported among children in Romanian orphanages. These findings led health-care workers to use new disposable syringes and needles for administering injections. Bythe late 1990s, reports suggested that new disposable syringes and needles had become standard for all injections. However, surveillance data collected by the Romanian Ministry of Health (MoH) during 1997-1998 indicated that acute hepatitis B virus (HBV) infection was associated with receiving injections among children aged <5 years. In Romania, injection frequently is used to administer medication, and nurses administer most injections. To identify the practices that might have resulted in injection-associated HBV transmission, selected clinic and hospital nurses were surveyed. This report summarizes the findings of the survey, which indicated that although nurses used new disposable syringes and needles, other inadequate infection-control practices might explain injection-associated HBV transmission. Results of the survey were used by the Romanian Coalition to Prevent Nosocomial Infections to prepare standards for injection safety to protect patients and health-care workers from HBV infection.
Intentional Self-injection With HIV
Authors: Rif S. El-Mallakh
Journal: JAMA (1992)

<h3>To the Editor.</h3> —Several workers have expressed concern that psychopathology may play a predisposing role in the acquisition of human immunodeficiency virus (HIV) infection.<sup>1,2</sup>We have recently encountered an unusual case that illustrates an extreme example of the role of psychopathology as a risk factor for HIV infection. A 45-year-old female laboratory technologist was seen in consultation for repeated intentional self-injection with hazardous biomaterials. She had a long psychiatric history marked by repeated suicide attempts, impulsive and occasionally violent acts, and dissociative episodes, all compatible with borderline personality disorder. In early 1989, after nearly 15 years of minimal psychiatric difficulties, increased domestic strife led to a resurgence of symptoms that necessitated psychiatric hospitalization. Her anxiety, dysphoria, dissociation, and suicidal tendencies, in the absence of any evidence of psychosis, were treated with 12 mg/d of perphenazine for several months with seemingly good response. During a work pass arranged in preparation
The Principles and Practice of Hygiene.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Personal Beauty and Racial Betterment.
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Monkeypox Case Investigation — Cook County Jail, Chicago, Illinois, July–August 2022
Authors: Liesl M. Hagan, Amy Beeson, Sarah Hughes, Rashida Hassan, Lauren Tietje, Ashley A. Meehan, Hillary Spencer, Janice Turner, Morgan Richardson, Jourdan Howard, Anne Schultz, Salma Ali, Margaret Mary Butler, Diana Arce Garza, Clint N. Morgan, Chantal Kling, Nicolle Baird, Michael B. Townsend, William C. Carson, David Lowe, Nhien T. Wynn, Stephanie R. Black, Janna L. Kerins, Josh Rafinski, Andrew Defuniak, Priscilla Auguston, Emily Mosites, Isaac Ghinai, Chad Zawitz
Journal: MMWR Morbidity and Mortality Weekly Report (2022)

Knowledge about monkeypox transmission risk in congregate settings is limited. In July 2022, the Chicago Department of Public Health (CDPH) confirmed a case of monkeypox in a person detained in Cook County Jail (CCJ) in Chicago, Illinois. This case was the first identified in a correctional setting in the United States and reported to CDC during the 2022 multinational monkeypox outbreak. CDPH collaborated with CCJ, the Illinois Department of Public Health (IDPH), and CDC to evaluate transmission risk within the facility. Fifty-seven residents were classified as having intermediate-risk exposures to the patient with monkeypox during the 7-day interval between the patient's symptom onset and his isolation. (Intermediate-risk exposure was defined as potentially being within 6 ft of the patient with monkeypox for a total of ≥3 hours cumulatively, without wearing a surgical mask or respirator, or potentially having contact between their own intact skin or clothing and the skin lesions or body fluids from the patient or with materials that were in contact with the patient's skin lesions or body fluids.) No secondary cases were identified among a subset of 62% of these potentially exposed residents who received symptom monitoring, serologic testing, or both. Thirteen residents accepted postexposure prophylaxis (PEP), with higher acceptance among those who were offered counseling individually or in small groups than among those who were offered PEP together in a large group. Monkeypox virus (MPXV) DNA, but no viable virus, was detected on one surface in a dormitory where the patient had been housed with other residents before he was isolated. Although monkeypox transmission might be limited in similar congregate settings in the absence of higher-risk exposures, congregate facilities should maintain recommended infection control practices in response to monkeypox cases, including placing the person with monkeypox in medical isolation and promptly and thoroughly cleaning and disinfecting spaces where the person has spent time. In addition, officials should provide information to residents and staff members about monkeypox symptoms and transmission modes, facilitate confidential monkeypox risk and symptom disclosure and prompt medical evaluation for symptoms that are reported, and provide PEP counseling in a private setting.
OxMIF: a druggable isoform of macrophage migration inhibitory factor in cancer and inflammatory diseases
Authors: Michael Thiele, Seamas C Donnelly, Robert A Mitchell
Journal: Journal for ImmunoTherapy of Cancer (2022)

Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine with a pleiotropic spectrum of biological functions implicated in the pathogenesis of cancer and inflammatory diseases. MIF is constitutively present in several cell types and non-lymphoid tissues and is secreted after acute stress or inflammation. MIF triggers the release of proinflammatory cytokines, overrides the anti-inflammatory effects of glucocorticoids, and exerts chemokine function, resulting in increased migration and recruitment of leukocytes into inflamed tissue. Despite this, MIF is a challenging target for therapeutic intervention because of its ubiquitous nature and presence in the circulation and tissue of healthy individuals. Oxidized MIF (oxMIF) is an immunologically distinct disease-related structural isoform found in the plasma and tissues of patients with inflammatory diseases and in solid tumor tissues. MIF converts to oxMIF in an oxidizing, inflammatory environment. This review discusses the biology and activity of MIF and the potential for autoimmune disease and cancer modification by targeting oxMIF. Anti-oxMIF antibodies reduce cancer cell invasion/migration, angiogenesis, proinflammatory cytokine production, and ERK and AKT activation. Anti-oxMIF antibodies also elicit apoptosis and alter immune cell function and/or migration. When co-administered with a glucocorticoid, anti-oxMIF antibodies produced a synergistic response in inflammatory models. Anti-oxMIF antibodies therefore counterregulate biological activities attributed to MIF. oxMIF expression has been observed in inflammatory diseases (eg, sepsis, psoriasis, asthma, inflammatory bowel disease, and systemic lupus erythematosus) and oxMIF has been detected in ovarian, colorectal, lung, and pancreatic cancers. In contrast to MIF, oxMIF is specifically detected in plasma and/or tissues of diseased patients, but not in healthy individuals. Therefore, as a druggable isoform of MIF, oxMIF represents a potential new therapeutic target in inflammatory diseases and cancer. Fully human, monoclonal anti-oxMIF antibodies have been shown to selectively bind oxMIF in preclinical and phase I studies; however, additional clinical assessments are necessary to validate their use as either a monotherapy or in combination with standard-of-care regimens (ie, immunomodulatory agents/checkpoint inhibitors, anti-angiogenic drugs, chemotherapeutics, and glucocorticoids).
The Value of Neomycin in a Neomycin-Steroid Cream
Authors: Charles M. Davis
Journal: JAMA (1968)

Twenty-seven patients with inflammatory and infected dermatoses were treated with a dexamethasone sodium phosphate cream or a combination neomycin-dexamethasone sodium phosphate cream. Symmetrical areas were treated with the two preparations for a paired comparison in a double-blind fashion. The clinical responses were equally satisfactory with both preparations. Neomycin was not effective topically in eradicating bacteria from the skin lesions.
Malaria Acquired by Accidental Needle Puncture
Authors: Nassif J. Cannon
Journal: JAMA (1972)

<h3>To the Editor.—</h3> In 1971, only 57 of the 3,047 cases of malaria reported in the United States were acquired within the country. Nine of these 57 cases of malaria were acquired through blood transfusion; 46 were needle induced in narcotic addicts who shared syringes; and one was classified as "cryptic."<sup>1</sup>The 57th case occurred in a third-year medical student (case 2) who accidentally pricked himself with a needle contaminated by blood from a Vietnam returnee with fatal<i>Plasmodium falciparum</i>malaria (case 2). <h3>Report of Cases.—Case 1.—</h3> A 21-year-old soldier, previously stationed in South Vietnam, had experienced intermittent chills, fever, nausea, and vomiting since Oct 4, 1971. The patient returned to the United States Oct 12, and was admitted to the Birmingham Veterans Administration Hospital, Oct 14. He reportedly took chloroquine and primaquine regularly for 11 months while in Vietnam; however, diphenyldiaminosulfone was only irregularly taken. Results
An Epidemic in an Eskimo Village Due to Group-B Meningococcus
Authors: Thomas H. Corbett
Journal: JAMA (1966)

Six cases of meningococcemia with unusual clinical manifestations occurred in Barrow, Alaska, in October and November 1964. Four of the six cases were in adults, and two of these were fatal. Meningitis, as defined by white blood cells in the spinal fluid, was not seen.