tbuckley/cabot-search huggingface dataset:
PHYSIOLOGICAL BASIS FOR SURGICAL MANAGEMENT OF HIATAL HERNIA
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Veterinary Oncology: Fido and Fluffy Get Latest Cancer Treatments
Journal: JNCI Journal of the National Cancer Institute (1989)

Journal Article Veterinary Oncology: Fido and Fluffy Get Latest Cancer Treatments Get access JNCI: Journal of the National Cancer Institute, Volume 81, Issue 24, 20 December 1989, Page 1859, https://doi.org/10.1093/jnci/81.24.1859 Published: 20 December 1989
Unilateral small kidney
Authors: H. L. Neiman
Journal: JAMA (1977)

<h3>Common</h3> Chronic pyelonephritis Obstructive renal atrophy Renal artery stenosis with ischemia (eg, arteriosclerosis, thromboembolism, fibromuscular hyperplasia, congenital stenosis) <h3>Uncommon</h3> Congenital hypoplastic kidney Partial nephrectomy Radiation therapy Renal infarction (late) Tuberculosis <h3>Diagnosis</h3> Chronic pyelonephritis. <h3>Comment</h3> The excretory urogram demonstrates a poorly functioning, small right kidney and a normal left kidney (Fig 1). A selected view from the early arterial phase of an aortogram shows reduced vascularity of the small right kidney (Fig 2). Capillary phase of the aortogram shows indentations on the outline of the small right kidney with clear demarcation of cortex and medulla (Fig 3). Unilateral small kidney, as seen here, may result from a number of causes. First, however, the "small" kidney must be defined. In general, renal size is proportional to body size. In children 1 1/2 to 14 years of age, the average kidney length corresponds to
Non synchronous vs synchronous biventricular stimulation may induce further increase in ventricular systolic performance G.B. Perego, R. Chianca, M. Facchini, E. Balla, M. Negretto*, I. Vicini*, S. Cavagli�*, G. Osculati., H.S.Luca - Istituto Auxologico Italiano., Milan, Italy,, *Medtronic Italia
Journal: Journal of the American College of Cardiology (2001)
Narcotics and Medical Practice
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Spinal Manipulation
Authors: W. Nimmer
Journal: JAMA (1983)

It was a pleasure reviewing this book. There are too few succinct and up-to-date books on spinal manipulation. The increasing numbers of people using manipulation and its acceptance by patients as one of many available treatment modalities make this book well worth reading. The first chapter is an excellent introduction to the history and art of manipulation of the spine. This chapter is enlightening and stimulating to anyone interested in manipulation. It begins with the bone setters, who are known to have existed as long as there are records and to have "practiced since prehistoric times known to Hippocrates and the physicians of ancient Rome." The historical role of osteopathy in the history of medicine is respectfully treated. The areas on diagnosis are excellent. The section on manipulative treatment of the patient is well illustrated and specific. The table of contents and index ably direct one to specific areas of
Preparations and Appliances
Journal: BMJ (1926)

MEDICAL DEFENCE UNION.t BRI' plaiits, shrubs, anid trees.It is a volumiie less for the coniscien- tious reader than for the judicious skipper; and it will move almost to tears those gardeners amongst us who just now are looking out ever;y nmorniing expecting to see -dahlias and geraniunms cut dowin by frost, for there is no winiter in Madeira.Dr. Grabham's book, which is called The Garden Interests of Madeira," is illustrated by several pictures,
Leaving
Authors: Mark A. Stafford
Journal: Annals of Internal Medicine (1993)

Ad Libitum1 September 1993LeavingMark A. Stafford, MDMark A. Stafford, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-119-5-199309010-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail I am leaving.I am not quitting.After ten years in Primary Care General Internal MedicineI have decided I must leave.No, I am not disillusioned with the field of medicine.Yes, I will encourage my sons and daughters to pursue careers in medicine, still the noblest of the professions.No, I was not unhappy with the relationships I formed with my patients and their families.No, my income was not inadequate.No, my practice environment was not unpleasant.No, I did not suffer from low self-esteem as I related to my professional colleagues.I was well-trained in a ... Author, Article, and Disclosure InformationAffiliations: Previousarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 September 1993Volume 119, Issue 5Page: 435KeywordsEmergency departmentEmotionsFearForecastingNursing homesResidencySub-specialty care ePublished: 15 August 2000 Issue Published: 1 September 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Prevention of uterine perforation during curettage abortion
Authors: D. A. Grimes
Journal: JAMA (1984)

Although uterine perforation is a potentially life-threatening complication of curettage abortion, little is known about the risk factors associated with uterine perforation or how to prevent it. Using linear logistic regression, we analyzed 67,175 curettage abortions performed at 13 institutions in the United States from 1975 through 1978. The overall incidence of confirmed perforation was 0.9 per 1,000 abortions. Performance of the abortion by a resident rather than by an attending physician was a powerful risk factor for perforation (relative risk, 5.5; 95% confidence interval, 3.3 to 9.2). Use of<i>Laminaria</i>for dilation had a protective effect, although this effect was not statistically significant (relative risk, 0.17; 95% confidence interval, 0.02 to 1.2). Among factors beyond the control of the physician, advancement of gestational age and previous delivery were significant risk factors. Use of<i>Laminaria</i>and performance of the abortion by an attending physician considerably lowered the risk of uterine perforation. (<i>JAMA</i>1984;251:2108-2111)
Johann Georg Zimmermann Prizes for Cancer Research
Journal: JNCI Journal of the National Cancer Institute (1977)

Johann Georg Zimmermann Prizes for Cancer Research Get access JNCI: Journal of the National Cancer Institute, Volume 59, Issue 5, November 1977, Page 1573, https://doi.org/10.1093/jnci/59.5.1573 Published: 01 November 1977
Prognostic information (PI), psychological well-being, and quality of life for advanced cancer patients (ACP) in phase I trials and their spousal caregivers (SC).
Authors: Fay J. Hlubocky, David Cella, Tamara Sher, Mark J. Ratain, Christopher Daugherty
Journal: Journal of Clinical Oncology (2013)

16 Background: The impact of the physician’s (MD) disclosure of PI on the psychological well-being and quality of life (QoL) of clinical trial subjects with terminal disease on phase I trials has not been formally evaluated. Methods: A prospective cohort of ACP enrolling in phase I trials was assessed at baseline (T1) and one month (T2) utilizing various measures including: state-trait anxiety (STAI-S/T), depression (CES-D), quality of life/QoL (FACIT-Pal), and global health (SF-36). Semi-structured interviews of ACPs also evaluated MD-Pt communication re prognosis and worry about ACP death. Results: 100 subjects (50 Phase I ACPs and 50 SC) were separately interviewed at T1 and T2. For the population as a whole: median age 62 (28-78y); 51% male; 100% married; 88% Ca; 68% &gt; HS educ; 56% GI dx; 54% income &lt;$65,000 yr. At T1, 45% of ACPs acknowledged having a discussion re life expectancy with MD; 35% stated the MD gave a prognostic timeframe; and 41% reported worry re death. For SC at T1, 62% recalled a prognosis discussion with the MD; 50% stated MD gave a timeframe; 53% reported PI disclosure was initiated by the MD; 66% reported worry re ACP death. At T2, rates remained consistent for both ACP and SC with the exception of increased reported worry re ACP death at 55% and 70% respectively. At T2, ACP who denied a prognosis was given by the MD had higher STAI-S (35 ± 10 v 29 ± 9, p=0.03) and CES-D scores (16 ± 12 v 7 ± 4, p=0.01); and lower FACT-Pal scores (128 ± 18 v 153 ± 24, p=0.01). SC with acknowledgement of a prognostic timeframe given by the MD had higher STAI-S anxiety (39 ± 16 v 36 ± 16, p=0.04) at T2. Regression analyses revealed that ACP with acknowledgement of a prognostic timeframe given by the MD had poorer FACIT-Pal QoL over time. Also, SC with acknowledgement of a prognostic timeframe at T2 was negatively associated with SF-36 scores. ACP and SC qualitative responses re PI disclosure revealed salient themes: hope for a positive outcome or prolonged survival; stabilization of disease; emotional distress; ambivalence/fear; acceptance. Conclusions: Physician disclosure of a prognostic timeframe is negatively associated with QoL among clinical trial subjects and SC in phase I trials.
La práctica médica en los accidentes del trabajo.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Importance of Human Exposure Information: A Need for Exposure-Related Data Bases to Protect and Promote Public Healt
Authors: D. K. Wagener
Journal: Annual Review of Public Health (1995)

As a subfield of public health, environmental health is concerned with evaluating and ameliorating the effects of people on the environment and the effects of the environment on people. Separating hazards from risks, and characterizing the magnitude, likelihood, and uncertainty of risks is at the heart of environmental health in the 1990s. To this end, a full range of data is needed, including data that characterize the distribution of hazards, the population potentially at risk, and the contact between people and pollution that creates the risk. Several government-sponsored data systems contain information on a range of exposure estimators. The challenge is to develop meaningful, properly validated models to identify public health needs and evaluate public health programs.
THE MECHANISM OF THE CRISES IN FAMILIAL HEMOLYTIC JAUNDICE
Authors: P. W. C.
Journal: Annals of Internal Medicine (1948)

Editorial1 June 1948THE MECHANISM OF THE CRISES IN FAMILIAL HEMOLYTIC JAUNDICEP. W. C.P. W. C.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-28-6-1193 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the early publications of Chauffard it has been well known that patients with this disease are prone to suffer acute exacerbations which are commonly termed hemolytic crises—"crises de déglobulization." During such periods there is usually fever, malaise, prostration, shortness of breath, and often acute abdominal pain with anorexia and vomiting. There is a rapid increase in the anemia, so that the red cell count and hemoglobin are often reduced to half of the original figures within a week or less. In occasional cases this may progress to a fatal termination, but as a rule after one to two weeks...1 OWREN PA: Congenital hemolytic jaundice. The pathogenesis of the "hemolytic crises," Blood, 1948, iii, 231-248. CrossrefGoogle Scholar2 DAMESHEKSCHWARTZ WSO: Acute hemolytic anemia (acquired hemolytic icterus, acute type), Medicine, 1940, xix, 231-327. CrossrefGoogle Scholar3 DACIEMOLLISON JVPL: Survival of normal erythrocytes after transfusion to patients with familial hemolytic anemia, Lancet, 1943, i, 550-552. CrossrefGoogle Scholar4 DAMESHEK W: The hemolytic crisis, Blood, 1948, iii, 307-308 (Editorial). CrossrefGoogle Scholar5 SCOTT AM: The serial onset of acute blood crises in an entire family, Lancet, 1935, ii, 872-874. CrossrefGoogle Scholar6 DAMESHEK W: Familial hemolytic crisis. Report of three cases occurring within ten days, New England Jr. Med., 1941, cciv, 52-56. CrossrefGoogle Scholar7 Editorial (M.S.S.): The concept of hypersplenism, Ann. Int. Med., 1946, xxv, 868-870. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited bySalmonella Septicemia and Aplastic Crisis in a Patient with Sickle-Cell AnemiaSalmonella Septicemia and Aplastic Crisis in a Patient with Sickle-Cell AnemiaHEMOLYTIC CRISIS IN HEREDITARY SPHEROCYTOSIS: STUDY OF A FAMILY OF FIVE WITH CONCURRENT CRISES*JONAH G. LI, M.D., IRVIN G. VOTH, M.D., EDWIN E. OSGOOD, M.D., F.A.C.P. 1 June 1948Volume 28, Issue 6Page: 1193-1196KeywordsAbdominal painAnemiaDyspneaFeversHemoglobinHemolytic jaundiceVomiting ePublished: 1 December 2008 Issue Published: 1 June 1948 PDF downloadLoading ...
Abstract 2205: Intraventricular Septal Intramural Asynchrony in Patients with Dilated Cardiomyopathy Using Tissue Velocity Imaging Correlates with the Severity of Myocardial Fibrosis
Authors: Jun Tanaka, Satoshi Nakatani, Makoto Amaki, Hideaki Kanzaki, Shuji Hashimoto, Hatsue Ishibashi-Ueda, Masafumi Kitakaze, Kazumasa Harada, Iwao Kuwajima
Journal: Circulation (2008)

Dilated cardiomyopathy (DCM) is histologically characterized by myocardial fibrosis and cellular hypertrophy. These myocardial changes may affect timing of regional peak contraction. We investigated whether there was a correlation between intraventricular septal (IVS) intramural asynchrony based on tissue velocity imaging and the histologic changes. We obtained apical 4-chamber tissue velocity images in 27 normal subjects and 22 patients with DCM undergoing myocardial biopsy using Vivid 7 (GE). We set 6 tandem regions of interest (ROIs) on the mid level of the IVS and measured the time to peak myocardial contraction (Ts) from the QRS onset at each ROI. We defined the standard deviation of Ts (Ts-SD) as an index of IVS asynchrony. Further, we analyzed a correlation between Ts-SD and the degree of myocardial fibrosis and cellular hypertrophy. The degree of myocardial fibrosis and cellular hypertrophy was graded qualitatively (0 to 3 scale) according to the percent of fibrosis occupied of the tissue sample and cell size. Ts-SD was larger in patients with DCM compared with normal subjects (13.9±12.3 vs. 6.2±4.0 ms, p&lt;0.05), suggesting asynchronous contraction of IVS in DCM. Ts-SD showed a significant correlation with the degree of myocardial fibrosis (grade 1, 6.9±3.5 ms; grade 2, 15.7±3.5 ms; grade 3, 25.9±5.3 ms; p&lt;0.05), while not with that of cellular hypertrophy (p=0.50). There was intramural asynchrony in IVS in DCM. This method could predict the degree of myocardial fibrosis noninvasively. Because myocardial fibrosis is the substrate for heart failure in DCM, the present method should provide clinically important information.
Serious arrhythmias during labor and delivery in women with heart disease
Authors: R. C. Spritzer
Journal: JAMA (1970)

The sudden onset of ventricular tachycardia and complete heart-block was documented via a continuous electromagnetic tape recording of the electrocardiogram during labor, delivery, and in the immediate postpartum period in two asymptomatic women with rheumatic heart disease. Monitoring of the ECG by an oscilloscope is recommended for the detection of unexpected and potentially life-threatening arrhythmias during childbirth in patients with heart disease.
Highlights
Journal: JAMA Internal Medicine (2019)

Sawaya and colleagues performed this cost-effectiveness analysis to estimate the quality of life and economic outcomes associated with 12 cervical cancer screening strategies among women aged 21 to 65 years.Results showed that cytologic testing every 3 years for women aged 21 to 29 years with either continued triennial cytologic testing or switching to a lowcost, high-risk human papillomavirus test every 5 years from age 30 to 65 years conferred a reasonable balance of benefits, harms, and costs from both a societal and health care sector perspective.Feldman provides the Invited Commentary.
Clinical Connections
Journal: Arthritis & Rheumatology (2020)

BAFF is a vital B cell survival and differentiation factor.Genetic elimination of the Baff gene or pharmacologic neutralization of BAFF prevents or ameliorates lupus in mouse models.In contrast, pharmacologic neutralization of BAFF has been far less effective in human subjects, with many systemic lupus erythematosus (SLE) patients failing to achieve a meaningful clinical response.By inference, BAFF-independent pathways contribute importantly to human SLE.Stohl et al developed a murine model in which SLE develops in a BAFF-independent manner by introducing into BAFF-deficient NZM 2328 mice a Bcl2 transgene (Tg) expressed only in B cells (NZM.Baff -/-.Bcl2 Tg mice).In these mice, survival of B cells does not depend upon BAFF-triggered signals.NZM.Baff -/-.Bcl2 Tg mice developed fullblown serologic, histologic, and clinical SLE despite the lifelong absence of BAFF.Importantly, these mice remained responsive to BAFF, since reintroduction of the Baff gene further accelerated the course of disease.Accordingly, NZM.Baff -/-.Bcl2 Tg mice may serve as a valuable and powerful murine model for the study of BAFF-independent SLE and the interplay between BAFF-dependent and BAFF-independent pathogenic pathways.
Incorrect Number and Phrasing
Authors: Peter Heinz-Erian, Andrea Spitzmu ¨ller, Hans Schro, Robert Birnbacher
Journal: JAMA (1998)

Maternal Smoking and Inhibition of Fetal Growth FactorTo the Editor.-Maternalsmoking during pregnancy often results in smaller than normal neonates. 1The mechanisms by which maternal smoking impairs fetal growth are as yet undefined.Insulinlike growth factor I (IGF-I) is an essential regulator of fetal growth 2 and may be a target for the growthretarding effects of smoking.We measured concentrations of IGF-I and its major binding protein (IGF-BP3) in cord serum of 10 smoking and 9 nonsmoking mothers (median age, 27 years and 28 years, respectively) who, after an otherwise entirely uneventful pregnancy, gave birth to normal-term neonates.The smoking group by history had had at least 15 cigarettes daily for longer than the last 2 months of gestation.The nonsmoking control group was neither actively nor passively exposed to cigarette smoke.For assessment of nicotine exposure, we also determined concentrations of the nicotine metabolite cotinine in maternal hair obtained at delivery.Hair samples of 50 mg were digested overnight at 50°C with 0.6N sodium hydroxide.The cotinine content of the extract was measured by enzyme-linked immunosorbent assay. 3The detection limit of the cotinine assay was 0.1 ng/mg of hair and the interassay coefficients of variation were less than 9%.Concentrations of IGF-I and IGF-BP3 in umbilical cord serum (after separation from each other by acid extraction) were determined by specific radioimmunoassays, 4,5 and the coefficients of interassay variation of both assays were less than 7%.Maternal hair cotinine content, fetal birth weights, and cord serum concentrations of IGF-I and IGP-BP3 for the smoking and nonsmoking groups are shown in the Table.These findings show that IGF-I concentrations in cord serum of neonates born to nicotine-exposed mothers were significantly lower than neonates of non-nicotine-exposed mothers.Since IGF-BP3 concentrations were similar in both groups, we suspect that the decrease of IGF-I concentrations in the nicotineexposed group was not caused by increased binding to IGF-BP3 but rather by decreased production or enhanced degradation of IGF-I.Growth retardation in neonates of smoking mothers may be related to an influence of nicotine on the generation or processing of IGF-I.In light of the well-recognized lifelong health consequences of fetal growth retardation after maternal smoking in pregnancy, further detailed investigations of the effects of nicotine exposure on the IGF system in the perinatal period are warranted.