tbuckley/cabot-search huggingface dataset:
The FOXO1TAD-p300-Mediated Lineage Survival Transcription Program Is a Targetable Dependency of Mantle Cell Lymphoma
Authors: Ja-Young Jang, Heng Pan, Maurizio Di Liberto, Lapo Alinari, Giorgio Inghirami, Robert A. Baiocchi, Olivier Elemento, Selina Chen-Kiang, Jihye Paik
Journal: Blood (2022)
Characteristics of Circulating KSHV-Infected Cells during Active KSHV+ Multicentric Castleman Disease
Authors: Gregoire Martin De Fremont, Anthony Vanjak, Zineb Sbihi, Silene Knapp, Margaux Garzaro, Marwa Chbihi, Benjamin Fournier, Justine Poirot, Antoine Dossier, Juliette Villemonteix, Veronique Meignin, Lionel Galicier, Rémi Bertinchamp, Jérôme Le Goff, Maud Salmona, Edouard Flamarion, Charles Cassius, Céleste Lebbé, Anne Marie Ronchetti, Sylvain Latour, Guislaine Carcelain, Eric Oksenhendler, David Boutboul
Journal: Blood (2022)
Unbiased NGS Approach for IGHV Mutational Status, Clonal Space and Immune Repertoire Assessment in Chronic Lymphocytic Leukemia
Authors: Jorge Gonzalez-Puelma, Julieta Sepulveda-Yanez, Jorge Torres-Almonacid, Diego Alvarez-Saravia, Maria Elena Marquez, Hermy Alvarez-Ojeda, Daniela Cardemil, Roberto Uribe-Paredes, Pablo Oppezzo, Marcelo Navarrete
Journal: Blood (2022)
Combination of Ibrutinib Plus Venetoclax with MRD-Driven Duration of Treatment Results in a Higher Rate of MRD Negativity in IGHV Unmutated Than Mutated CLL: Updated Interim Analysis of FLAIR Study
Authors: Talha Munir, Alexandra Pitchford, Adrian Bloor, Andrew Pettitt, Piers E.M. Patten, Francesco Forconi, Anna Schuh, Christopher P Fox, Simona Gatto, Ben Kennedy, John Gribben, Nicholas Pemberton, Oonagh Sheehy, Gavin Preston, Dena Howard, Anna Hockaday, David Cairns, Sharon Jackson, Natasha Greatorex, Nichola McWhirter, Jane Shingles, Kate Cwynarski, Shankara Paneesha, David Allsup, Andrew Rawstron, Peter Hillmen
Journal: Blood (2022)
Mitochondrial RNA stimulates beige adipocyte development in young mice
Authors: Anh Cuong Hoang, László Sasi-Szabó, Tibor Pál, Tamás Szabó, Victoria Diedrich, Annika Herwig, Kathrin Landgraf, Antje Körner, Tamás Röszer
Journal: Nature Metabolism (2022)

Abstract Childhood obesity is a serious public health crisis and a critical factor that determines future obesity prevalence. Signals affecting adipocyte development in early postnatal life have a strong potential to trigger childhood obesity; however, these signals are still poorly understood. We show here that mitochondrial (mt)RNA efflux stimulates transcription of nuclear-encoded genes for mitobiogenesis and thermogenesis in adipocytes of young mice and human infants. While cytosolic mtRNA is a potential trigger of the interferon (IFN) response, young adipocytes lack such a response to cytosolic mtRNA due to the suppression of IFN regulatory factor (IRF)7 expression by vitamin D receptor signalling. Adult and obese adipocytes, however, strongly express IRF7 and mount an IFN response to cytosolic mtRNA. In turn, suppressing IRF7 expression in adult adipocytes restores mtRNA-induced mitobiogenesis and thermogenesis and eventually mitigates obesity. Retrograde mitochondrion-to-nucleus signalling by mtRNA is thus a mechanism to evoke thermogenic potential during early adipocyte development and to protect against obesity.
Highly aneuploid non-small cell lung cancer shows enhanced responsiveness to concurrent radiation and immune checkpoint blockade
Authors: Liam F. Spurr, Carlos A. Martinez, Wenjun Kang, Mengjie Chen, Yuanyuan Zha, Robyn Hseu, Stanley I. Gutiontov, William T. Turchan, Connor M. Lynch, Kelli B. Pointer, Paul Chang, Septimiu Murgu, Aliya N. Husain, Brittany Cody, Everett E. Vokes, Christine M. Bestvina, Jyoti D. Patel, Maximilian Diehn, Thomas F. Gajewski, Ralph R. Weichselbaum, Steven J. Chmura, Sean P. Pitroda
Journal: Nature Cancer (2022)
FDA Gives Nod to Mirvetuximab Soravtansine
Journal: Cancer Discovery (2022)

The FDA has granted accelerated approval to mirvetuximab soravtansine to treat patients with folate receptor alpha (FRα)-positive, platinum-resistant epithelial ovarian, primary peritoneal, and fallopian tube cancers. The FDA also approved the VENTANA FOLR1 (FOLR-2.1) RxDx Assay companion diagnostic device, which detects the FRα protein and could determine which patients will likely respond to the antibody-drug conjugate.
Distinct changes in endosomal composition promote NLRP3 inflammasome activation
Authors: Zhirong Zhang, Rossella Venditti, Li Ran, Zengzhen Liu, Karl Vivot, Annette Schürmann, Juan S. Bonifacino, Maria Antonietta De Matteis, Romeo Ricci
Journal: Nature Immunology (2022)

Abstract Inflammasome complexes are pivotal in the innate immune response. The NLR family pyrin domain containing protein 3 (NLRP3) inflammasome is activated in response to a broad variety of cellular stressors. However, a primary and converging sensing mechanism by the NLRP3 receptor initiating inflammasome assembly remains ill defined. Here, we demonstrate that NLRP3 inflammasome activators primarily converge on disruption of endoplasmic reticulum–endosome membrane contact sites (EECS). This defect causes endosomal accumulation of phosphatidylinositol 4-phosphate (PI4P) and a consequent impairment of endosome-to- trans -Golgi network trafficking (ETT), necessary steps for endosomal recruitment of NLRP3 and subsequent inflammasome activation. Lowering endosomal PI4P levels prevents endosomal association of NLRP3 and inhibits inflammasome activation. Disruption of EECS or ETT is sufficient to enhance endosomal PI4P levels, to recruit NLRP3 to endosomes and to potentiate NLRP3 inflammasome activation. Mice with defects in ETT in the myeloid compartment are more susceptible to lipopolysaccharide-induced sepsis. Our study thus identifies a distinct cellular mechanism leading to endosomal NLRP3 recruitment and inflammasome activation.
Dentate gyrus astrocytes exhibit layer-specific molecular, morphological and physiological features
Authors: Julian Karpf, Petr Unichenko, Nicholas Chalmers, Felix Beyer, Marie-Theres Wittmann, Julia Schneider, Elif Fidan, Andre Reis, Jan Beckervordersandforth, Sebastian Brandner, Stefan Liebner, Sven Falk, Andreas Sagner, Christian Henneberger, Ruth Beckervordersandforth
Journal: Nature Neuroscience (2022)
Vemircopan (ALXN2050) Monotherapy in Paroxysmal Nocturnal Hemoglobinuria: Interim Data from a Phase 2 Open-Label Proof-of-Concept Study
Authors: Peter J. Browett, Austin Kulasekararaj, Rosario Notaro, Masayo Ogawa, Antonio Risitano, Ji Yu, Jong Wook Lee
Journal: Blood (2022)
ASC4KIDS: A Multicenter, Open-Label, Phase Ib/II Study to Determine the Dose and Safety of Asciminib in Pediatric Patients with Chronic Myeloid Leukemia in Chronic Phase
Authors: Nobuko Hijiya, Shruti Kapoor, Matthias Hoch, Laurence Descamps, Kohinoor Dasgupta, Nicholas Ramscar
Journal: Blood (2022)
Serial HLA-Antibody Testing Identifies Waning Calculated Panel Reactive Antibodies (cPRA) in Platelet Transfusion Refractory Patients with Hematologic Malignancies
Authors: Kanak Parmar, Hamilton C Tsang, Danny Youngs, Zach Gill, Rida A. Hasan, Monica B. Pagano, John R. Hess, Terry B. Gernsheimer, Idoia Gimferrer, Sandhya Panch
Journal: Blood (2022)
Safety and Activity of Flotetuzumab in Pediatric and Young Adult Patients with Relapsed/Refractory Acute Myeloid Leukemia: Results from the COG PEPN1812 Phase 1 Trial
Authors: Adam J. Lamble, Xiaowei Liu, Charles Minard, Olga Militano, Melanie Brooke Bernhardt, Todd M. Cooper, Edward A. Kolb, Erin H. Breese, Elizabeth Fox, Sarah K Tasian, Brenda J. Weigel
Journal: Blood (2022)
Gut Microbiome Composition Is Associated with Engraftment Syndrome in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation
Authors: Rena Feinman, Ariel A. Aptekmann, Iriana Colorado, Samuel Roy, Joshua Zenreich, Sophia H. Dar, Adolfo Aleman, Rashmi Unawane, Margaret Zhuang, Megan Korkoleo, Mariefel Vendivil, Andrea Ricourt, Andrew McConnell, Phyllis McKiernan, Anqi Dai, Andrew L. Pecora, Noa Biran, David Siegel, Jonathan U. Peled, Michele L. Donato
Journal: Blood (2022)
Multiyear, Real-World, Retrospective Cohort Study Using a Patient-Centric Approach to Evaluate the Burden of Hemophilia B in the United States
Authors: Priya Patel, Yong Chen, Arianna Burton, Jose Alvir, Darren Kailung Jeng, Anna Stachel, Jiayin Xue, Emily Cibelli, Patrick F. Fogarty
Journal: Blood (2022)
German AMLCG-Survivorship Study: Anxiety and Depression Symptoms in AML Long-Term Survivors
Authors: Dennis Görlich, Eva Telzerow, Maria Cristina Sauerland, Anna Sophia Moret, Maja Rothenberg-Thurley, Friederike H.A. Mumm, Susanne Amler, Wolfgang E. Berdel, Bernhard J. Wörmann, Utz Krug, Jan Braess, Pia Heußner, Wolfgang Hiddemann, Karsten Spiekermann, Klaus H. Metzeler
Journal: Blood (2022)
Structural Variation Cooperates with Permissive Chromatin to Control Enhancer Hijacking-Mediated Oncogenic Transcription
Authors: Giovanni A. Botten, Yuannyu Zhang, Kseniia Dudnyk, Xin Liu, Jacob T. Sanders, Aygun Imanci, Nathalie Droin, Hui Cao, Pranita Kaphle, Kathryn E. Dickerson, Mingyi Chen, Weina Chen, Eric Solary, Peter Ly, Jian Zhou, Jian Xu
Journal: Blood (2022)
Real World Data on Outcomes of Anti-CD38 Antibody Refractory, Including Triple Class Refractory, Patients with Multiple Myeloma: A Multi-Institutional Report from the Canadian Myeloma Research Group (CMRG) Database
Authors: Alissa Visram, Alfredo De La Torre, Darrell White, Moustafa Kardjadj, Esther Masih-Khan, Michael P. Chu, Victor H Jimenez-Zepeda, Arleigh McCurdy, Richard Leblanc, Kevin Song, Hira S Mian, Martha L Louzada, Michael Sebag, Debra Bergstrom, Julie Stakiw, Anthony Reiman, Rami Kotb, Muhammad Aslam, Christopher P. Venner, Rayan Kaedbey, Engin Gul, Donna E. Reece
Journal: Blood (2022)
Ibrutinib Plus Fludarabine, Cyclophosphamide, and Rituximab As Inital Treatment for Chronic Lymphocytic Leukemia/ Small Lymphocytic Leukemia
Authors: Huayuan Zhu, Yeqin Sha, Yi Miao, Shuchao Qin, Hui Shen, Jingyan Qiu, Wei Wu, Yi Xia, Tonglu Qiu, Li Wang, Lei Fan, Wei Xu, Jianyong Li
Journal: Blood (2022)
Prognostic Impact of Day 14 Bone Marrow (D14 BM Bx) in Acute Myeloid Leukemia (AML) in the Setting of European Leukemianet (ELN) Risk Classification
Authors: Metodi Balev, Nicole Zubizarreta, Erin Bresnahan, Jonathan Feld, Marina Kremyanskaya, Alla Keyzner, Alan H. Shih, Bridget K Marcellino, Lewis R. Silverman, Michal Bar-Natan, John Mascarenhas, Douglas Tremblay
Journal: Blood (2022)
Meta-Analysis on Impact of Rituximab in Patients with Hematological Malignancies with Covid-19 Infection
Authors: Charan Thej Reddy Vegivinti, Tejo Niharika Musunuru, Rahul Kumar Thakur, Venkata Kiranmayi Kakumani, Ansh Krishnachandra Mehta, Eleftheria Atalla, Sahas Reddy Jitta, Mansi Mehta, Praneeth Reddy Keesari, Obuli srinivasan Gurunathan, Murali Mohan Reddy Gopi reddy
Journal: Blood (2022)
Second-Line Ponatinib in Chronic Phase Chronic Myeloid Leukemia (CML-CP) Patients Failing or Intolerant to First-Line Second Generation Tyrosine Kinase Inhibitor (TKI) Treatment: An Interim Analysis of the Prospective PONS Trial
Authors: Philipp le Coutre, Joachim R Göthert, Susanne Saussele, Uwe Pelzer, Lars Bullinger, Ahmet Elmaagacli, Christian Jehn, Frank Stegelmann, Andreas Hochhaus, Thomas Ernst, Andreas Burchert
Journal: Blood (2022)
Multivariable Analyses of Prognostic Factors for Progression-Free Survival (PFS) and Complete Response (CR) with Lenalidomide, Bortezomib, and Dexamethasone (RVd) Alone Versus Rvd Plus Autologous Stem Cell Transplantation (ASCT) in Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM) in the Determination Phase 3 Trial
Authors: Hani Hassoun, Susanna J. Jacobus, Paul G. Richardson, Jeffrey A. Zonder, Peter M. Voorhees, Jonathan L. Kaufman, Andrew J. Yee, Emma C. Scott, Pallawi Torka, Edward Libby, Brandi Reeves, Michael L. Wang, Larry D. Anderson, Carter Milner, Cristina J. Gasparetto, Mounzer Agha, Abdullah Khan, David Duane Hurd, David Avigan, Caitlin Costello, Andrzej Jakubowiak, Sagar Lonial, Noopur Raje, Eva Medvedova, Philip L. McCarthy, Robert Z. Orlowski, Omar Nadeem, Jacob P. Laubach, Marcelo C. Pasquini, Sergio A. Giralt, Kelly Masone, Mehmet K. Samur, Aurore Perrot, Philippe Moreau, Herve Avet-Loiseau, Edie A. Weller, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Blood (2022)
Synergistic Activity of Luspatercept and Erythroid Stimulating Agents Combination for Treatment of Anemia in Lower-Risk Myelodysplastic Syndromes
Authors: Rami S. Komrokji, Luis E. Aguirre, Najla Al Ali, Onyee Chan, Andrew Kuykendall, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, David A. Sallman
Journal: Blood (2022)
Phase 2, Open-Label Study of Ciltacabtagene Autoleucel, an Anti-BCMA CAR-T Cell Therapy, in Chinese Patients with Relapsed/Refractory Multiple Myeloma (CARTIFAN-1): 26-Month Median Follow-up
Authors: Jian-Qing Mi, Wanhong Zhao, Hongmei Jing, Weijun Fu, Jianda Hu, Lijuan Chen, Yiwen Zhang, Dan Yao, Hui Li, Jordan M Schecter, Fan Yang, Huabin Sun, Sen Hong Zhuang, Da Xu, Tracy Luo, Xiaohu Fan, Ting Niu, Jie Jin, Sai-Juan Chen
Journal: Blood (2022)
A Phase 1a/b Dose Escalation Study of the FLT3/BTK Inhibitor Luxeptinib (CG-806) in Patients with Relapsed or Refractory Acute Myeloid Leukemia
Authors: Aaron D Goldberg, Maro Ohanian, Paul B. Koller, Mohamad Cherry, Jessica K. Altman, Benjamin Tomlinson, Namrata Sonia Chandhok, Donna Nguyen Haney, Jia Hu, Ranjeet Kumar Sinha, William G Rice, Rafael Bejar
Journal: Blood (2022)
Prognostic Impact of Minimal Disseminated Disease By Digital PCR for Pediatric ALK-Positive Anaplastic Large Cell Lymphoma
Authors: Reiji Fukano, Yuka Iijima-Yamashita, Hideto Iwafuchi, Atsuko Nakazawa, Akiko Moriya Saito, Tetsuya Takimoto, Masahiro Sekimizu, Yutaka Suehiro, Shunji Hasegawa, Tetsuya Mori, Keizo Horibe
Journal: Blood (2022)
Diagnosis and Treatment of MPN in Real Life - Interim-Analysis of an Exploratory Chart Review on 960 ET and MF Patients in Germany
Authors: Andreas Schmidt, Christiane Bernhardt, Anette Fries, Kathleen Jentsch-Ulrich, Andreas Josting, Stephan Kreher, Marcel Reiser, H. Tilman Steinmetz, Hans Tesch, Bernhard Kaufmann, Uta Rager, Carl C. Crodel, Francesca Palandri, Florian H. Heidel
Journal: Blood (2022)
Evaluation of CNS Involvement in Secondary AML: Incidence and Impact on Outcome
Authors: Matthew Lee, John Wei, Hiba Narvel, Sindhu Vikash, Josette Kamel, Amanda Lombardo, Fariha Khatun, Jennat Mustafa, Felisha Joseph, Anjali Naik, Kailyn Gillick, Richard Elkind, Yang Shi, Yanhua Wang, Kira Gritsman, Ulrich G. Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Nishi Shah, Marina Konopleva, Dennis Cooper, Ira Braunschweig, Amit Verma, Swati Goel, R. Alejandro Sica
Journal: Blood (2022)
Oral Anti-CD3 and Bioencapsulated FVIII Therapy Exhibit Distinct Mechanisms That Suppress Inhibitor Formation in Hemophilia a
Authors: Moanaro Biswas, Thais Bertolini, Kaman So, Jyoti Rana, Sandeep R.P. Kumar, Sha Cao, Hongyu Gao, Xiaoling Xuei, Henry Daniell, Roland W. Herzog
Journal: Blood (2022)
Long-Term Outcome of Second Allogeneic Stem Cell Transplantation (HSCT2) for Primary Graft Failure in Patients with Acute Leukemia in Remission: A Study on Behalf of the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Authors: Arnon Nagler, Myriam Labopin, Alexander D. Kulagin, Andrea Velardi, Jaime Sanz, Hélène Labussière-Wallet, Victoria Potter, Jurgen Kuball, Simona Sica, Elena N. Parovichnikova, Wolfgang Bethge, Xavier Leleu, Uwe Platzbecker, Friedrich Stölzel, Fabio Ciceri, Mohamad Mohty
Journal: Blood (2022)
Contribution of Obinutuzumab to Acalabrutinib Therapy in Patients with Treatment-Naive Chronic Lymphocytic Leukemia: Analysis of Survival Outcomes By Genomic Features
Authors: Matthew S. Davids, Jeff P. Sharman, Toby A. Eyre, Jennifer A. Woyach, Paulo Andre P. de Miranda, Mina Shahkarami, Anna Butturini, Ugochinyere Emeribe, John C. Byrd
Journal: Blood (2022)
Relationship between Molecular Profile and Platelet Function and Thrombin Generation in Patients with Essential Thrombocytemia
Authors: Mercedes Gasior Kabat, Elena Monzón Manzano, Paula Acuña, María Teresa Alvarez Román, Elena G Arias-Salgado, María Isabel Rivas Pollmar, Matias Facal Giuliani, Patricia Gonzalez Marugan, Sara García Barcenilla, Fernando Gomez Aguado, Concepción Ramos Castro, Cédric Hermans, Víctor Jiménez Yuste, Nora V. Butta
Journal: Blood (2022)
Health-Related Quality of Life (HRQoL) in Patients with Relapsed and Refractory Multiple Myeloma (RRMM) Who Are Triple-Class Exposed to an Immunomodulatory Agent, a Proteasome Inhibitor, and an Anti-CD38 Antibody
Authors: Nina Shah, Ravi Vij, Jenna S. Roberts, Ivana Rajkovic, Rebecca Silbermann, Jens Hillengass, Sujith Dhanasiri, Julia Braverman, Abigail McMillan, Devender Dhanda
Journal: Blood (2022)
Treatment of Steroid-Refractory Chronic Graft-Versus-Host Disease Patients in a Limited-Resource Center in Northeastern Mexico. Single Center Experience
Authors: Perla R.R. Colunga-Pedraza, Edgar Ulises Ulises Coronado-Alejandro, Luz María Barbosa Castillo, Fernando De La Garza, Eliezer Tomas Tomas Gomez Gomez, Andres Gomez-De Leon, Julia Esther Colunga Pedraza, Cesar Homero Gutierrez-Aguirre, Olga Graciela Cantú Rodriguez, David Gomez-Almaguer
Journal: Blood (2022)
Results from the First Phase 3 Crovalimab (C5 Inhibitor) Study (COMMODORE 3): Efficacy and Safety in Complement Inhibitor-Naive Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)
Authors: Hui Liu, Linghui Xia, Jianyu Weng, Fengkui Zhang, Chuan He, Sujun Gao, Jinsong Jia, Alice C. Chang, Pontus Lundberg, Camelia S. Sima, Jane Shi, Zhenyu Xiao, Yuchen Zhang, Zilu Zhang, Rong Fu
Journal: Blood (2022)
Exploring the Efficiency and Survival of CAR T-Cell Therapy in DLBCL Patients with MYC and/or TP53 Abnormalities
Authors: Peihao Zheng, Rui Liu, Teng Xu, Fan Yang, Shaomei Feng, Yuelu Guo, Lixia Ma, Hui Shi, Hongwei Yu, Biping Deng, Xiaoyan Ke, Kai Hu
Journal: Blood (2022)
EP0042, a Dual FLT3 and Aurora Kinase Inhibitor: Preliminary Results of an Ongoing Phase I/IIa First in Human Study in Patients with Relapsed/Refractory Acute Myeloid Leukemia
Authors: David Taussig, Jenny O'Nions, Mojca Jongen-Lavrencic, Jeroen J. Janssen, David C. de Leeuw, Peter T. Tan, Sue Brook, Katie Stoddart, Hendrik-Tobias Arkenau, Geoff Fisher
Journal: Blood (2022)
Long-Term Outcome of Adolescents and Young Adults with Chronic Primary Immune Thrombocytopenia (ITP)
Authors: Alexandra Schifferli, Gautier Le Gavrian, Nathalie Aladjidi, Guillaume Moulis, Bertrand Godeau, Thierry Leblanc, Marc Michel, Guy Leverger, Helder Fernandes, Thomas Kuehne
Journal: Blood (2022)
Variability in End-of-Life Care and Perception of Palliative Care Among Physicians in the Hematology Unit of a Reference Service in the State of Bahia, Brazil
Authors: Diego Lopes Paim Miranda, Alini Maria Orathes Ponte Silva, Lais T. Silva, Marianna Batista Vieira Lima, Monica Botura, Edvan De Queiroz Crusoe, Marco Aurelio Salvino
Journal: Blood (2022)
Trial in Progress: Follicular Lymphoma Outcomes in Relapsed/Refractory Patients Treated with Systemic Therapy in a Real-World Assessment (FLORA)
Authors: Emmanuel Bachy, Gandhi Laurent Damaj, Qiufei Ma, Christian Hampp, James Harnett, Rachel E. Sobel, Jessica J. Jalbert, Ruben G.W. Quek, Wenhui Wei, Ning Wu, Vera Mastey, Joy Wang, Anit Bajwa, Benedikt Maissenhaelter, Chantal van Gils, Shivani Aggarwal, Aafia Chaudhry, Hesham Mohamed, Srikanth R. Ambati, Catherine Thieblemont
Journal: Blood (2022)
Deciphering Treatment Patterns in Non-Severe Aplastic Anemia: An International Observational Study
Authors: Bruno Fattizzo, Carmelo Gurnari, Giulio Cassanello, Marta Bortolotti, Hussein Awada, Sabrina Giammarco, Dario Consonni, Simona Sica, Shreyans Gandhi, Roochi Trikha, Jaroslaw P. Maciejewski, Austin Kulasekararaj, Wilma Barcellini
Journal: Blood (2022)
Prognostic Stratification of Patients with Primary Central Nervous System Lymphoma Using Serum β2-Microglobulin Levels
Authors: Yeokyeong Shin, Hyungwoo Cho, Shin Kim, Hyung-Don Kim, Jin-Sook Ryu, Jooryung Huh, Chan-Sik Park, Sang-wook Lee, Cheolwon Suh
Journal: Blood (2022)
Real-World Outcome of Treatment with Single-Agent Ibrutinib in Patients with Chronic Lymphocytic Leukemia: Results from the Italian Study Evidence
Authors: Stefano Molica, Potito Rosario Scalzulli, Lydia Scarfò, Attilio Guarini, Roberta Murru, Paolo Sportoletti, Ferdinando Frigeri, Francesco Albano, Nicola Di Renzo, Alessandro Sanna, Idanna Innocenti, Massimo Massaia, Marta Coscia, Elsa Pennese, Caterina Patti, Gianluigi Reda, Agostino Tafuri, Giulia Regazzoni, Michele Di Candia, Francesca Romana Mauro
Journal: Blood (2022)
Hydroxyurea Is Associated with Later Onset of Occurrence of Acute Splenic Sequestration Episodes in Sickle Cell Disease: Lessons from the European Sickle Cell Disease Cohort - Hydroxyurea (ESCORT-HU) Study
Authors: Mariane de Montalembert, Frédéric Galactéros, Lena Oevermann, Giovanna Cannas, Laure Joseph, Gylna Loko, Narcisse Elenga, Malika Benkerrou, Maryse Etienne-Julan, Marie-Pierre Castex, Regine Grosse, Valentine Brousse
Journal: Blood (2022)
Lentiviral-mediated Gene Therapy for Patients with Fanconi Anemia [Group A]: Updated Results from Global RP-L102 Clinical Trials
Authors: Agnieszka Czechowicz, Julián Sevilla, Claire Booth, Rajni Agarwal, Josune Zubicaray, Paula Río, Susana Navarro, Kritika Chetty, Grainne O'Toole, Jinhua Xu-Bayford, Philip Ancliff, Elena Sebastián, Grace Choi, Miriam Zeini, Eileen Nicoletti, John E Wagner, Gayatri R. Rao, Adrian J. Thrasher, Jonathan D. Schwartz, Maria Grazia Roncarolo, Juan A. Bueren
Journal: Blood (2022)
Subcutaneous Concizumab Prophylaxis in Patients with Hemophilia A or B with Inhibitors: Efficacy and Safety Results By Hemophilia Subtype from the Phase 3 Explorer7 Trial
Authors: Melissa Frei-Jones, Katarina Cepo, Roseline d'Oiron, Ai Sim Goh, Mary Mathias, Jan Odgaard-Jensen
Journal: Blood (2022)
Assessment of the Molecular International Prognostic Scoring System (IPSS-M) Risk Stratification Model in Hypoplastic Myelodysplastic Syndromes
Authors: Luis E. Aguirre, Najla Al Ali, Somedeb Ball, Avani M Singh, Akriti G Jain, Onyee Chan, Zaker I. Schwabkey, Sara M Tinsley-Vance, Andrew Kuykendall, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, David A. Sallman, Rami S. Komrokji
Journal: Blood (2022)
Clinical and Genomics Characteristics of Multiple Myeloma with Extramedullary Disease in the Mmrf Registry
Authors: Mateo Mejia Saldarriaga, David S Jayabalan, Aubrie Sowa, Jorge Monge, Cara A. Rosenbaum, Roger Pearse, Ruben Niesvizky, Sanjay Patel, Mark Bustoros
Journal: Blood (2022)
Poor Outcomes Among Pediatric Non-Down Syndrome Acute Megakaryocytic Leukemia Patients Irrespective of Receipt of Hematopoietic Stem Cell Transplant
Authors: Gabriela Llaurador, Matthew Willis, Michele Redell, M Monica Gramatges, Swati Naik, Robert A. Krance, Erin E Doherty, Alexandra McLean Stevens
Journal: Blood (2022)
Effects of CD24 "Don't Eat Me" Signal Blockade in Combination with Anti-CD47 and Rituximab in Mantle-Cell Lymphoma
Authors: Andrea Aroldi, Mario Mauri, Matteo Villa, Federica Malighetti, Federica Cocito, Claudia Voena, Roberto Chiarle, Luca Mologni, Rocco Piazza, Carlo Gambacorti-Passerini
Journal: Blood (2022)
Predictors of Veno-Occlusive Disease (VOD) of the Liver in Patients Treated with Inotuzumab Ozogamicin (InO) Containing Regimen in B-Cell Acute Lymphoblastic Leukemia
Authors: Jayastu Senapati, Elias Jabbour, Nicholas Short, Nitin Jain, Partow Kebriaei, Richard E Champlin, Issa F. Khouri, Elizabeth J Shpall, Patrice Nasnas, Aram Bidikian, Rebecca Garris, Hagop Kantarjian
Journal: Blood (2022)
Phase 2 Trial to Evaluate Safety of Subcutaneous Epcoritamab Monotherapy in the Outpatient Setting Among Patients with Relapsed or Refractory Diffuse Grade 1-3a Large B-Cell and Follicular Lymphoma (EPCORE NHL-6)
Authors: Jeff P. Sharman, Ralph V. Boccia, Thomas Doerr, Kristin Conte, Yang Bai, Brian Elliott, David J. Andorsky
Journal: Blood (2022)
Validation and Use of Predictive Scoring Systems for Molecular Responses in 5,203 Persons with Chronic Myeloid Leukemia
Authors: Xiaoshuai Zhang, Bingcheng Liu, Jian Huang, Gongli Zhang, Xiaoli Liu, Na Xu, Weiming Li, Xin Du, Jianyu Weng, Hai Lin, Rong Liang, Chunyan Chen, Huanling Zhu, Ling Pan, Yunfan Yang, Xiaodong WANG, Guohui Li, Zhuogang Liu, Zhenfang Liu, Jianda Hu, Chunshui Liu, Li Fei, Wei Yang, Li Meng, Robert Peter Gale, Xiao Jun Huang, Qian Jiang
Journal: Blood (2022)