tbuckley/cabot-search huggingface dataset:
Spain Leads World in Organ Donation and Transplantation
Authors: X. Bosch
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Suxamethonium apnoea.
Authors: M. Whittaker, M. D. Vickers
Journal: BMJ (1968)

<b>Background:</b> Ventilator Associated Pneumonia (VAP) is the most common infection in Intensive Care Units (ICUs) which increases the length of ICU stay, duration of mechanical ventilation, and mortality. Good oral hygiene care by means of effective plaque control has thus been advocated as an essential nursing care to prevent colonization of dental plaque by respiratory pathogens, and possibly prevent VAP. <b>Objective:</b> This randomized controlled trial aimed to compare the incidence of VAP in mechanically ventilated patients treated with pharmacological (topical oral chlorhexidine) and combination (toothbrushing plus chlorhexidine) oral care. <b>Methodology:</b> A total of 63 mechanically ventilated patients treated at Hospital Universiti Sains Malaysia (USM) Intensive Care Unit (ICU) were randomly assigned into two groups: a control group of 32 patients who received 0.2% chlorhexidine gluconate mouthrinse twice daily and a study group of 31 patients who received 0.2% chlorhexidine gluconate mouthrinse twice daily plus tooth brushing. This study protocol was approved by the USM Human Research Ethics Committee. <b>Results:</b> Of 63 patients, 9 developed VAP, making the total incidence of VAP as 14.3%. Of these 9 patients who developed VAP, 6 were from the control group (18.8%, 95%CI: 6.8-40.1), and 3 were from the trial group (9.7%,95%CI:1.9-28.2). <b>Conclusion:</b> VAP was less likely to occur in the trial group than in the control group, indicating that tooth brushing twice daily in addition to standard care of 0.2% chlorhexidine gluconate mouth rinse was effective in reducing the incidence of VAP in mechanically ventilated patients treated at Hospital USM ICU
THE YELLOW-FEVER SITUATION ON THE MEXICAN BORDER.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Poster Session 1: Immunosuppression
Journal: Hepatology (2014)

both areas were combined, there was a significant difference between stage 1 vs stage 3 (p<0.011),stage 1 vs stage 4 (p< 0.005) and stage 0 vs stage 4 (p< 0.033).HRI measurements: HRI measurements for patients with <5% steatosis vs those with >5% steatosis were different (P<0.0002).Summary: a) SWE can distinguish normal liver/mild fibrosis from cirrhosis in both non-OLT and OLT patents.b) BMI>40 may affect SWE measurements.c) HRI can be used to identify patients with clinically significant steatosis (>5%).Conclusions: SWE and HRI measurements are non-invasive methods that can assist in clinical decision making in the assessment of fibrosis and steatosis in both OLT and non-OLT patients although caution should be exercised over the interpretation of these measurements in patients with a BMI>40.
Elementary Practical Biochemistry.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Magnetically Actuated SiCN‐Based Ceramic Microrobot for Guided Cell Delivery
Authors: Ki‐Won Gyak, Sungwoong Jeon, Laura Ha, Sangwon Kim, Jin‐young Kim, Kwang‐Sup Lee, Hongsoo Choi, Dong‐Pyo Kim
Journal: Advanced Healthcare Materials (2020)

Adv. Healthcare Mater. 2019, 8, 1900739 In the original version of this article, some of the funding information in the Acknowledgements section was incorrect. The correct funding information is as follows: K.-W.G., S.J., and L.H. contributed equally to this work. The authors thank the CCRF of the DGIST for technical support. This work was supported by the National Research Foundation of Korea (NRF) and the DGIST R&D Program funded by the Ministry of Science and ICT (2017K1A1A2013237 & 19-CoE-BT-02) and by the National Research Foundation (NRF) of Korea grant funded by the Korean government (MSIP) (NRF-2017R1A3B1023598 and NRF-2016R1A2-B4008473). The current position of S.K. is Semiconductor R&D Center, Samsung Electronics, South Korea. The authors apologize for any confusion caused.
Non-Small Cell Lung Cancer Guidelines
Authors: David S Ettinger, Gerold Bepler, Raphael Bueno, Andrew Chang, Joe Y Chang, Lucian R Chirieac, Thomas A D'Amico, Todd L Demmy, Steven J Feigenberg, Frederic W Grannis, Thierry Jahan, Mohammad Jahanzeb, Anne Kessinger, Ritsuko Komaki, Mark G Kris, Corey J Langer, Quynh-Thu Le, Renato Martins, Gregory A Otterson, Francisco Robert, David J Sugarbaker, Douglas E Wood
Journal: Journal of the National Comprehensive Cancer Network (2006)

Lung cancer is still the leading cause of cancer death worldwide, and non-small cell lung cancer accounts for 80% to 85% of all lung cancer cases. Surgery, radiation therapy, and chemotherapy are the 3 modalities commonly used to treat patients with NSCLC and can be used either alone or in combination depending on the disease status. The 2006 NCCN Non-Small Cell Lung Cancer Guidelines provide the latest updates in the management of this disease, including stage regrouping and changes in screening recommendations for high-risk patients and in treatment recommendations for several stages. In addition, principles of systemic therapy were expanded to include adjuvant treatment. For the most recent version of the guidelines, please visit NCCN.org
Abstract 2863: Long non-coding RNA <i>LINC00152</i> plays an oncogenic role via targeting MET, STAT3 signaling in esophagus adenocarcinoma
Authors: Matthew Xiao, Zhuwen Wang, Jules Lin, David G. Beer, Andrew C. Chang, Guoan Chen
Journal: Cancer Research (2019)

Abstract Esophageal cancer remains a threat to public health with an increasing incidence and low survival rate world wide. Long non-coding RNA, LINC00152 has been linked to several human cancers and promotes cell proliferation in lung, gastric, hepatocellular, colorectal, and clear cell renal carcinoma. The expression of LINC00152 and its roles in esophagus adenocarcinomas (EAC), however, are unknown. The objective of this study is to investigate the role of LINC00152 in EAC. We used the esophageal cancer cell lines Flo-1, OE19, and OE33 for in vitro study. siRNA of specific to LINC00152 was used to knockdown LINC00152 followed by cell proliferation, colony formation, invasion and migration assays. Real-time PCR assay was used for detecting mRNA expression and Western blot for examining altered proteins expression affected by LINC00152 knockdown. Data analysis were performed using excel and Prism. The difference of variables was analyzed using the Student’s T-test. We found that LINC00152 was increased in EAC as compared to Barrett, low-grad displasia or high-grad dysplasia. The LINC00152 expression was decreased more than 90% after LINC00152 knockdown with siRNA on Flo, OE19 and OE33 cells measured by RT-PCR. Cell proliferation, colony and invasion were decreased significantly after LINC00152 siRNA transfection on these EAC cell lines. Apoptosis was also induced. Mechanistic study indicated that MET protein was significantly decreased in OE33 cells after LINC00152 knockdown, while STAT3 decreased in Flo cells. P21, p27 and Myc was decreased in all 3 cell lines. In this study we found that LINC00152 knockdown could inhibit cell proliferation, colony formation, cell migration and invasion, as well as trigger apoptosis via targeting multiple oncogenic signaling. We also found LINC00152 was increased in EAC tumors. Our study indicates that LINC00152 plays an important role in EAC and is potentially a diagnostic marker. Further characterization of LINC00152 as a novel therapeutic target of EAC is warranted. Citation Format: Matthew Xiao, Zhuwen Wang, Jules Lin, David G. Beer, Andrew C. Chang, Guoan Chen. Long non-coding RNA LINC00152 plays an oncogenic role via targeting MET, STAT3 signaling in esophagus adenocarcinoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 2863.
<i>La Confusion Mentale Primitive. Stupidité, Démence Aigue, Stupeur Primitive</i>. Par le Dr. Ph. Chaslin, Médicin Adjoint de l'Hospice de Bicêtre. etc. (<i>Primary Mental Confusion. Stupidity. Acute Dementia, Primary Stupor</i>. By Dr. Ph. Chaslin.) Paris, 1895
Journal: American Journal of Psychiatry (1895)
DISINFECTION OF THE URINE IN TYPHOID FEVER.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Regional variations in the use of medical services and the accountability of the profession
Authors: J. F. Boyle
Journal: JAMA (1985)

Elsewhere in this issue ofThe Journal<sup>1</sup>there appears yet another in a growing list of reports on variations in rates of utilization of health services or variations in medical practice patterns. The current report leaves something to be desired in its methodology, completeness of analysis, and some of the deductions derived from the authors' data. For example, while pointing out that differences in fertility rates completely explained the variation in the observed-to-expected rates of cesarean section, the authors then include 7,260 days of hospitalization for cesarean section in computing potential savings that might occur were such variations eliminated. It would seem equally illogical to add 6,324 days for reduction of fractured femurs unless the authors are proposing a safety program to prevent people from breaking their legs. These two items account for over 30% of the excess bed use cited. In a similar fashion, one might also question
Automotive Medicine
Authors: Donald F. Huelke
Journal: JAMA (1971)

<h3>To the Editor.—</h3> In the Aug 24, 1970, issue ofThe Journal,<i>Proceedings of the Eleventh Annual Meeting, American Association for Automotive Medicine</i>was reviewed (<b>213</b>: 1347). Some of the remarks—"... a most miscellaneous collection..." and "The result is a great potpourri."—cause me to write this letter. To me, these statements would lead the readers of the review to believe that this collection of papers is not worth reading. I believe this is in error. The highway epidemic that we have in the United States is truly a tragedy which will require public health measures to combat the rising toll of injuries and deaths. This will mean sincere involvement of the medical profession. However, the majority of physicians do not appreciate the magnitude of the problem, have their own pet ideas for solution without proper scientific foundations, and in general do not know of the varieties of problems or potential
Chronic Fatigue
Authors: Robert J. Meth
Journal: JAMA (1989)

<h3>To the Editor. —</h3> As a busy family physician, I see patients complaining of chronic fatigue almost daily, so I was encouraged to see the article in the Aug 19 issue by Kroenke et al<sup>1</sup>regarding chronic fatigue in primary care. Since I agree that depression is one of the most common causes of chronic fatigue, I was glad to see that the physicians in the study used the Beck Depression Inventory, which I give to all of my patients complaining of fatigue. However, I was disappointed to note that despite the fact that 57 patients had psychometric testing scores suggestive of depression, only four patients were treated with antidepressants. The National Institute of Mental Health has recognized that primary care physicians are notoriously poor at diagnosing and treating depression, and this study suggests that the physicians involved were uncomfortable giving a trial of antidepressants to determine if it
ENDOSCOPIC SUBMUCOSAL DISSECTION WITH TRIANGULATED TRACTION WITH CLIP AND RUBBER BAND: THE “WALLET” STRATEGY
Authors: M Pioche, A Lupu, J Jacques, J Rivory, T Ponchon
Journal: Endoscopy (2019)

Nevertheless, it is technically challenging and new strategies to facilitate procedure are requested. Counter traction strategies allows enlarging submucosal space like in the clip and rubber band approaches. In the rectum, line traction makes a tangential traction without triangulation and is not really adaptive as the dissection progresses.
Incorrect Date
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Structure-Activity Relationships for Xenobiotic Transport Substrates and Inhibitory Ligands of P-Glycoprotein
Authors: Lisa J. Bain, James B. McLachlan, Gerald A. LeBlanc
Journal: Environmental Health Perspectives (1997)

The multixenobiotic resistance phenotype is characterized by the reduced accumulation of xenobiotics by cells or organisms due to increased efflux of the compounds by P-glycoprotein (P-gp) or related transporters. An extensive xenobiotic database, consisting primarily of pesticides, was utilized in this study to identify molecular characteristics that render a xenobiotic susceptible to transport by or inhibition of P-gp. Transport substrates were differentiated by several molecular size/shape parameters, lipophilicity, and hydrogen bonding potential. Electrostatic features differentiated inhibitory ligands from compounds not catagorized as transport substrates and that did no interact with P-gp. A two-tiered system was developed using the derived structure-activity relationships to identify P-gp transport substrates and inhibitory ligands. Prediction accuracy of the approach was 82%. We then validated the system using six additional pesticides of which tow were predicted to be P-gp inhibitors and four were predicted to be noninteractors, based upon the structure-activity analyses. Experimental determinations using cells transfected with the human MDR1 gene demonstrated that five of the six pesticides were properly catagorized by the structure-activity analyses (83% accuracy). Finally, structure-activity analyses revealed that among P-gp inhibitors, relative inhibitory potency can be predicted based upon the surface area or volume of the compound. These results demonstrate that P-gp transport substrates and inhibitory ligands can be distinguished using molecular characteristics. Molecular characteristics of transport substrates suggest that P-gp may function in the elimination of hydroxylated metabolites of xenobiotics.
Evaluation of hepatitis B virus (HBV) epidemiology, vaccine impact and treatment eligibility: a census-based community serological survey in Blantyre, Malawi
Authors: Alexander Stockdale, James Meiring, Isaac T. Shawa, Deus Thindwa, Niza Silungwe, Maurice Mbewe, Collins Mitambo, Rabson Kachala, Benno Kreuels, Pratiksha Patel, Priyanka Patel, Stephen Gordon, Anna Maria Geretti, Melita Gordon
Journal: Journal of Hepatology (2020)
FAMILY PERIODIC PARALYSIS AND ALLIED NEUROSES.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Recognizing and Treating Depression in the Elderly
Authors: M. J. Friedrich
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal