tbuckley/cabot-search huggingface dataset:
THE DIGESTIBILITY OF FISH
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Error in Flow Diagram
Authors: Manuele Casale, Lorenzo Sabatino, Fabrizio Salvinelli, Nicholas Reed
Journal: JAMA (2017)

Amy M. Valent, DO; Chris DeArmond, RN; Judy M. Houston, RPh; Srinidhi Reddy, MD; Heather R. Masters, MD; Alison Gold, MD; Michael Boldt, MD; Emily DeFranco, DO, MS; Arthur T. Evans, MD; Carri R. Warshak, MD
How readable are subject consent forms?
Authors: G. R. Morrow
Journal: JAMA (1980)

A consent to treatment form provides required information that a patient may use to give intelligent, informed consent to proposed treatment. This study applied two standard techniques to assess the degree to which 60 informed consent forms from five national cancer clinical trial groups were readable and understandable by patients. The forms were found slightly less difficult to comprehend than medical journals but substantially more difficult than comparable materials from the popular press. Three of four passages describing treatment methods, procedures, discomforts, and risks required a college level or greater reading ability to comprehend. Informed consent documents may not be understood by a substantial portion of patients who sign them. The very regulations designed to ensure a patient's informed cooperation with treatment may inadvertently lead to forms that are so complex as to make informed cooperation virtually impossible. (<i>JAMA</i>244:56-58, 1980)
Summary
Authors: M Costa
Journal: Gut (2004)

Neural information from the viscera to the central nervous system (CNS) plays a very important role in health and disease. Afferent neural activity from the gastrointestinal tract signals the CNS but the nature of the stimuli required to activate the visceral afferent neurones is still not well defined. Greater comprehension of the anatomy of visceral afferents and of the underlying mechanisms relating to visceral mechano- and chemoreception is required in order to identify rational therapeutic targets for the treatment of functional gastrointestinal diseases.
SOME ASPECTS OF BLOOD CHEMISTRY IN PREGNANCY
Journal: JAMA (1925)

The acceptance of the view that protein metabolism involves primarily the transformations of amino-acids —the degradation products of the proteins—in the organism has placed diverse aspects of bodily function in a new light. It has become easier also to realize why the proteins that are found in the urine under a variety of pathologic conditions are different from the albuminous compounds that are ingested. Wells 1 has pointed out that numerous attempts have been made by both chemical and immunologic methods to determine whether the proteins in the urine in nephritis come from the food, the blood, or from the renal cells themselves. In alimentary albuminuria, the urinary proteins seem not to be those of the food, but human proteins. In nephritis, differentiation between serum proteins and kidney proteins has not yet been satisfactorily accomplished. If urinary proteins do not represent the undestroyed residues of food proteins, it becomes a
When to Send Patients Abroad for Water Cures and Climatic Treatment.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Quality and duration of survival in glioblastoma multiforme. Combined surgical, radiation, and lomustine therapy
Authors: F. H. Hochberg
Journal: JAMA (1979)

A retrospective evaluation of the quality and length of survival of 74 patients nonrandomly receiving lomustine, 100 to 110 mg/sq m, following craniotomy and irradiation for glioblastoma multiforme was performed. After surgery all patients were capable of at least partial self-care. Patients receiving postoperative irradiation and lomustine had a median survival of 11.5 months. While receiving chemotherapy, 40% of these patients were capable of at least partial employment; 75% were able to care for themselves. These levels of function were stable for 70% of the average postoperative course (8.0 months), following which a decline ensued. (<i>JAMA</i>241:1016-1018, 1979)
The "Surfeit."
Authors: Bernard Wolff
Journal: JAMA (1897)

Atlanta, Ga., Feb. 14,1897. <h3>To the Editor:</h3> —Will the erudite editor of theJournalkindly inform me what is meant by the term "surfeit," as applied to the affection to which the death of medieval monarchs was commonly ascribed? We read that Henry VIII died of "a surfeit"; was this his malady, or is it a vaguely facetious reference to his uxoriousness? <h3>Answer:</h3> —Crapula (or cræpula). It is also<i>κραιπαλη</i>, a surfeit. A disorder from something taken into the stomach, and occasionally a sickness or at least a loathing of the offending matter. It sometimes signifies a plethora from indulgence and full but improper feeding, in which case perspiration is checked and eruptions formed on the skin. It is sometimes called the<i>cholera accidentalis</i>.—Bartholomew Parr's "London Medical Dictionary," 1819.
AERIAL TRANSMISSION OF TYPHOID FEVER.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ibrutinib combined with bendamustine and rituximab (BR) in previously treated chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL): First results from a randomized, double-blind, placebo-controlled, phase III study.
Authors: Asher Alban Akmal Chanan-Khan, Paula Cramer, Fatih Demirkan, Graeme Fraser, Rodrigo Santucci Silva, Halyna Pylypenko, Sebastian Grosicki, Ann Janssens, Alexander Pristupa, Jiri Mayer, Marie-Sarah Dilhuydy, Javier Loscertales, Nancy L. Bartlett, Abraham Avigdor, Simon Rule, Steven Sun, Michelle Mahler, Mariya Salman, Angela J. Howes, Michael J. Hallek
Journal: Journal of Clinical Oncology (2015)

LBA7005 The full, final text of this abstract will be available at abstracts.asco.org at 7:30 AM (EDT) on Saturday, May 30, 2015, and in the Annual Meeting Proceedings online supplement to the June 20, 2015, issue of the Journal of Clinical Oncology. Onsite at the Meeting, this abstract will be printed in the Saturday edition of ASCO Daily News.
Fetal Loss Associated With Excess Thyroid Hormone Exposure
Authors: Sophie Christin-Maitre, Francoise Duron
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE GREATEST RESORT IN AMERICA—THE SCENE OF THE 1904 SESSION.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Education
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Light Armour in Modern Warfare
Authors: C. W. Saleeby
Journal: BMJ (1940)

<h3>Abstract</h3> Many ideas about the evolution of specialization rely on trade-offs—an inability for one organism to express maximal performance in two or more environments. However, optimal foraging theory suggests that populations can evolve specialization on a superior resource without explicit trade-offs. Classical results in population genetics show that the process of adaptation can be biased toward further improvement in already productive environments, potentially widening the gap between superior and inferior resources. Here I synthesize these approaches with new insights on evolvability at low recombination rates, showing that emergent asymmetries in evolvability can push a population toward specialization in the absence of trade-offs. Simulations are used to demonstrate how adaptation to a more common environment interferes with adaptation to a less common but otherwise equal alternative environment. Shaped by recombination rates and other population-genetic parameters, this process results in either the retention of a generalist niche without trade-offs or entrapment at the local optimum of specialization on the common environment. These modeling results predict that transient differences in evolvability across traits during an episode of adaptation could have long-term consequences for a population’s niche.
Abstract 227: Skinned Myocardial Strips From Non-failing and Failing Human Hearts Produce More Force at Physiological Temperature
Authors: Bertrand C Tanner, Peter O Awinda, Cheavar A Blair, Maya E Guglin, Kenneth S Campbell
Journal: Circulation Research (2017)

Introduction: Heart failure contributes to 1 in 9 deaths in the United States. Contractile deficits at the myofilament level may contribute to the heart inadequately pumping blood throughout the body. Few studies have investigated force production and myosin cross-bridge kinetics at physiological temperature in human myocardium from non-failing and failing hearts. Hypothesis: Myosin cross-bridge kinetics speed up with temperature, thereby altering contractility in non-failing and failing human myocardium. Methods: Skinned myocardial strips from the left ventricle free wall were Ca 2+ -activated at 2.3 μm sarcomere length. Isometric force production and cross-bridge attachment and detachment rates were measured at 17 and 37°C (4 non-failing hearts, 8 failing hearts; 4-6 strips tested at each condition). Results: Maximal Ca 2+ -activated, force was ~35% greater in non-failing vs. failing tissue at both 17 and 37°C (p&lt;0.001 for condition effect). Moreover, increasing temperature from 17 to 37°C increased maximal force by roughly 30% and 40% in non-failing and failing myocardial strips, respectively (p&lt;0.001 for temperature effect). Ca 2+ -sensitivity of the force-pCa relationship was reduced for non-failing vs. failing myocardial strips (p=0.03 for condition effect), with differences in pCa 50 being greatest at 17°C between non-failing and failing samples. These contractile differences between non-failing and failing myocardium, were not driven via differences in myosin cross-bridge kinetics, which were similar among non-failing and failing samples at each temperature. However, faster cross-bridge cycling rates accompanied greater force production at physiological temperature in both non-failing and failing samples. Conclusions: These findings suggest that heart failure compromises force production without significantly altering cross-bridge kinetics, both at sub-physiological and physiological temperatures in human myocardium.
Assessing, accommodating, and interpreting the influences of heterogeneity.
Authors: T A Louis
Journal: Environmental Health Perspectives (1991)

Heterogeneity, ranging from measurement error to variation among individuals or regions, influences all levels of data collected for risk assessment. In its role as a nemesis, heterogeneity can reduce the precision of estimates, change the shape of a population model, or reduce the generalizability of study results. In many contexts, however, heterogeneity is the primary object of inference. Indeed, some degree of heterogeneity in excess of a baseline amount associated with a statistical model is necessary in order to identify important determinants of response. This report outlines the causes and influences of heterogeneity, develops statistical methods used to estimate and account for it, discusses interpretations of heterogeneity, and shows how it should influence study design. Examples from dose-response modeling, identification of sensitive individuals, assessment of small area variations and meta analysis provide applied contexts.
Alcohol, nutrient intake, and hypertension in US adults
Authors: H. W. Gruchow
Journal: JAMA (1985)

Data from the first Health and Nutrition Examination Survey were analyzed with multivariate statistical techniques to determine whether there was evidence for a contributory role of alcohol in hypertension and to provide a suitable perspective on the importance of nutrient variables compared with other established risk factors for hypertension. The results of these analyses reaffirm the importance of alcohol and sodium intakes on blood pressures among US adults. Potassium (inversely) and phosphorus (directly) were also identified as important nutrient predictors of higher systolic blood pressure. Calcium intake was significantly related to systolic blood pressure only among nonwhite men and was not a significant predictor of systolic pressure overall. In addition, the results of the study reemphasized the paramount importance of age, race, and obesity in determining hypertension. Current nutrient intakes, by comparison, are relatively less important. (<i>JAMA</i>1985;253:1567-1570)
Incorrect Residual Heparin Amount in: Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction: The TIME Randomized Trial
Journal: JAMA (2013)

Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery on Left Ventricular Function After Acute Myocardial Infarction: The TIME Randomized Trial
Naked
Authors: Atul Gawande
Journal: New England Journal of Medicine (2005)

There is an exquisite and fascinating scene in Kandahar, a movie set in Afghanistan under the Taliban regime, in which a male physician is asked to examine a female patient. They are separated by an opaque screen. Behind it, the woman is covered from head to toe by her burka. The two do not talk directly to each other. The patient's young son serves as the go-between. She has a stomachache, he says.“Does she throw up her food?” the doctor asks.“Do you throw up your food?” the boy asks.“No,” the woman says, perfectly audibly, but the doctor . . .
Mathematical modeling of BTX: biotransformation and transport in the subsurface.
Authors: L M Abriola, Y M Chen
Journal: Environmental Health Perspectives (1995)

A two-dimensional compositional model is presented; this model describes the transport and biotransformation of organic contaminants in a variably saturated subsurface environment. Modeled processes included mass exchange between constituent phases (water, air, soil, and organisms), advective and dispersive fluxes in the water phase, diffusive flux in the air phase, and biotransformation and biomass production in the biophase. In this model, solute transfer across air/water and water/solid interfaces is modeled using equilibrium relationships. Rate-limited mass transfer between the water and biophases is described with a linear driving force expression. Microbial degradation and biomass net growth are modeled by Monod-type kinetics. Solute transport and microbial growth equations are solved using an iterative Galerkin finite element method with a variable time-weighting scheme. Coupled biophase mass balance equations for each component are solved with a Newton-Raphson iterative scheme. Model capabilities are illustrated with two-dimensional, cross-sectional simulations of natural bioattenuation. The influence of biotransformation processes on the transport and extent of a toluene plume is examined.
Gauging the Accuracy of Laboratory Testing From Medicare Data
Authors: Barbara Seeger
Journal: JAMA (1993)

<h3>To the Editor.</h3> —I read with great interest the article by Drs Mennemeyer and Winkelman<sup>1</sup>evaluating patient outcomes as a tool for clinical laboratory quality assurance. The retrospective data suggest that patients are at increased risk for an adverse outcome when PT results are obtained and interpreted from a physician office laboratory. A patient tested in an office laboratory with PT test volume of less than 40 per month is at higher risk for stroke and acute myocardial infarction when compared with a similar patient tested in a commercial laboratory. An adverse outcome is also greater among patients who switch from one laboratory to another between successive PT testing. Mennemeyer and Winkelman fail to address how the variability of the sources and preparations of calcium and tissue thromboplastin were used in the various laboratories.<sup>2,3</sup>The PT results are not comparable from laboratory to laboratory without knowing the thromboplastin
Decreasing Rates of Induced Labor
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal