tbuckley/cabot-search huggingface dataset:
Post-COVID-19 cholangiopathy: does SARS-CoV-2 play a relevant role in histopathological findings?
Authors: Valéria Ferreira de Almeida e Borges, Helma Pinchemel Cotrim, Marcelo Costa Silva, Liliana Sampaio Costa Mendes, Francisco Guilherme Cancela Penna, Antônio Ricardo Cardia Ferraz de Andrade, Frederico Chaves Salomão, Juliana Daud, Luiz Antônio Rodrigues de Freitas
Journal: Journal of Hepatology (2022)
Identification of potential new serum biomarkers for clinically significant portal hypertension by proteomic profiling of circulating extracellular vesicles
Authors: Frane Pastrovic, Grgur Salai, Stela Hrkač, Ruđer Novak, Lovorka Grgurević, Marko Žarak, Kristian Podrug, Tajana Filipec Kanizaj, Tomislav Bokun, Ivica Grgurević
Journal: Journal of Hepatology (2022)
Liver-specific Tsg101 depletion causes apoptosis, cell death and liver failure
Authors: Surui Wang, Revathi Sekar, Jaroslaw Cendrowski, Ahmed Ghallab, Karsten Motzler, Yun Kwon, Susanne Seitz, Michael Roden, Adriano Maida, Jan G. Hengstler, Stephan Herzig, Marta Miaczynska, Anja Zeigerer
Journal: Journal of Hepatology (2022)
Virologic response to bulevirtide is delayed in cirrhotic HDV patients with clinically significant portal hypertension
Authors: Mathias Jachs, Caroline Schwarz, Marlene Panzer, Lukas Hartl, Simona Bota, Petra Munda, Albert F Stättermayer, Ivo Graziadei, Stephan Aberle, Michael Gschwantler, Heinz Zoller, Michael Trauner, Mattias Mandorfer, Peter Ferenci, Thomas Reiberger
Journal: Journal of Hepatology (2022)
Hippo inactivation drives BMI1-associated proliferative hepatocarcinogenesis in chronic hepatitis B virus infection
Authors: Xufeng Luo, Rui Zhang, Yaojie Liang, Stefan Schefczyk, Shi Liu, Hideo Baba, Christian Lange, Heiner Wedemeyer, Mengji Lu, Ruth Broering
Journal: Journal of Hepatology (2022)
Improvements in quality of life in odevixibat responders and nonresponders: an analysis of pooled data from the PEDFIC 1 and PEDFIC 2 studies
Authors: Cara L. Mack, Chad Gwaltney, Quanhong Ni, Qifeng Yu, Velichka Valcheva, Lise Kjems, Patrick Horn
Journal: Journal of Hepatology (2022)
Myosteatosis and excessive visceral adipose tissue as prognostic factors in patients with hepatocellular carcinoma treated with sorafenib
Authors: Min Kyu Kang, Yu Rim Lee, Jae Young Jang, Jung Eun Song, Young Oh Kweon, Won Young Tak, SE Young Jang, Changhyeong Lee, Byung Seok Kim, Jae-Seok Hwang, Woo Jin Chung, Byoung Kuk Jang, Jeong Ill Suh, Jung Gil Park, Soo Young Park
Journal: Journal of Hepatology (2022)
Human resident liver macrophages protect against metabolic stress in obesity
Authors: Emelie Barreby, Benedikt Strunz, Valerio Azzimato, Joanne X. Shen, Léa Naudet, Isabella Sönnerborg, André Sulen, Sebastian Nock, Laura Levi, Cecilia Morgantini, Achilleas Fardellas, Helene Johansson, Greg Nowak, Per Stal, Ewa Ellis, Erik Naslund, Volker Lauschke, Niklas Björkström, Ping Chen, Myriam Aouadi
Journal: Journal of Hepatology (2022)
Validation of AI-assisted method of liver fat measurement in adults with type 2 diabetes
Authors: Athena Dworakowski, Wenjie Pang, Sherif Boulos, Sofie De Meyer, Jian Yeo, Gaurav Gulsin, Abhishek Dattani, Emer Brady, Joanna Bilak, Sarah Ayton, Alastair Moss, Michael House, Tim St Pierre, Gerry McCann
Journal: Journal of Hepatology (2022)
In AF, CV benefits of catheter ablation vs. medical therapy may vary by age
Authors: Ali Almhri, Darryl P. Leong
Journal: Annals of Internal Medicine (2022)

Bahnson TD, Giczewska A, Mark DB, et al. Association between age and outcomes of catheter ablation versus medical therapy for atrial fibrillation: results from the CABANA trial. Circulation. 2022;145:796-804. 34933570.
Benign course of HBV reactivations during DAAs in untreated ENI with HBV-HCV co-infections correlates with different HBsAg kinetics compared to NAs treated CHB patients
Authors: Piero Colombatto, Elena Palmisano, Gabriele Ricco, Daniela Cavallone, Filippo Oliveri, Barbara Coco, Antonio Salvati, Veronica Romagnoli, Lidia Surace, Maria Linda Vatteroni, Mauro Pistello, Agostino Virdis, Ferruccio Bonino, Maurizia Brunetto
Journal: Journal of Hepatology (2022)
Association of novel lifestyle- and whole foods base inflammation scores with metabolic dysfunction-associated fatty liver disease: a population-based study among iranian adults
Authors: Ehsaneh Taheri, Roberd M Bostick, Behzad Hatami, Mohammadamin Pourhoseingholi, Hamid Asadzadeh Aghdaei, Alireza Moslem, Alireza MosusaviJarahi, Mohammadreza Zali
Journal: Journal of Hepatology (2022)
Diagnostic accuracy of non-invasive tests for cirrhotic NASH-an individual participant data meta-analysis
Authors: Ferenc Mozes, Jenny Lee, Yasaman Vali, Emmanuel Selvaraj, Arjun Jayaswal, Jerome Boursier, Elisabetta Bugianesi, Ramy Younes, Monica Lupsor-Platon, Salvatore Petta, Toshihide Shima, Takeshi Okanoue, Sanjiv Mahadeva, Wah-Kheong Chan, Gideon Hirschfield, Peter Eddowes, Philip N. Newsome, Vincent Wai-Sun Wong, Victor de Lédinghen, Jeremy Cobbold, Yoshio Sumida, Akira Okajima, Jörn Schattenberg, Christian Labenz, Won Kim, Myoung Seok Lee, Guruprasad Aithal, Naaventhan Palaniyappan, Cristophe Cassinotto, Sandeep Aggarwal, Harshit Garg, Geraldine Ooi, Atsushi Nakajima, Masato Yoneda, Ming-Hua Zheng, Céline Fournier, Andreas Geier, Theresa Tuthill, Carla Yunis, Quentin Anstee, Stephen Harrison, Patrick Bossuyt, Michael Pavlides
Journal: Journal of Hepatology (2022)
Survival of patients with advanced hepatocellular carcinoma treated with sorafenib in France during 2009–2018: analysis of the French hospital and claim database
Authors: Jean-Pierre Bronowicki, Julien Dupin, Alexandre Pissewoewoe Tanang, Anika Gilbert-Marceau, Jean-Frédéric Blanc, Pierre Nahon, Caroline Laurendeau, Stéphane Bouée, Mélina Gilberg
Journal: Journal of Hepatology (2022)
Excess mortality risk among hepatitis C patients after being “cured” in the interferon-free era: results from three population-based cohorts
Authors: Victoria Hamill, Stanley Wong, Jennifer Benselin, Mel Krajden, Peter Hayes, David Mutimer, Amanda Yu, John Dillon, Will Gelson, Hector Velasquez, Philip Johnson, Stephen Barclay, Maria Alvarez, Hidenori Toyoda, Kosh Agarwal, Andrew Fraser, Sofia Bartlett, Mark Aldersley, Andrew Bathgate, Mawuena Binka, Paul Richardson, Joanne Morling, Stephen Ryder, Douglas Macdonald, Sharon Hutchinson, Eleanor Barnes, Neil Guha, William Irving, Naveed Janjua, Hamish Innes
Journal: Journal of Hepatology (2022)
Hepatic venous pressure gradient (HVPG) measured at events is lower in non-alcoholic fatty liver disease (NAFLD) associated cirrhosis as compared to alcoholic cirrhosis
Authors: Lubomir Skladany, Daniela Jancekova, Michal Žilinčan, Stanislav Okapec, Janka Vnencakova, Svetlana Adamcova Selcanova, Michal Kukla, Tomáš Koller
Journal: Journal of Hepatology (2022)
Feasibility and effectiveness of hepatitis C micro-elimination among 19 prisons of northern India
Authors: Kanudeep Kaur, Gagandeep Singh Grover, Praveen Kumar Boora, V K Bansal, Veena Singh, S Suman, Virendra Singh, Arka De, Rajashree Sen, Sanjay Sarin, Sonjelle Shilton
Journal: Journal of Hepatology (2022)
Cholangiopathy after severe COVID-19: what do we know so far?
Authors: Valéria Ferreira de Almeida e Borges, Helma Pinchemel Cotrim, Marcelo Simão Ferreira, José Humberto Caetano Marins, Haroldo Luis Oliva Gomes Rocha, Leonardo Augusto Dias Nascimento, Mayra Machado Fleury Guedes, Julia Esteves Guerra
Journal: Journal of Hepatology (2022)
Rituximab is a safe and effective treatment for patients with autoimmune hepatitis: results from the Spanish registry for cholestatic and autoimmune hepatitis
Authors: Ana Barreira, Maria Carlota Londoño, Carmen Álvarez-Navascués, Carlos Ferre Aracil, Indhira Perez Medrano, Juan Turnes, Diana Horta, Álvaro Díaz-González, Fernando Diaz Fontela, Magdalena Salcedo, Mar Riveiro Barciela
Journal: Journal of Hepatology (2022)
Quantitative HBsAg (qHBsAg) as an end point to stop nucleos (t) ide analogues in chronic hepatitis B: a meta-analysis with meta-regression
Authors: Seng Gee Lim, Ada Ee Der Teo, Edwin Shih-Yen Chan, Wah Wah Phyo, David Hsing Yu Chen, Carol Anne Hargreaves
Journal: Journal of Hepatology (2022)
Heterologous prime-boost immunotherapy circumvents tolerance and induces broadly neutralizing antibodies that protects against hepatitis B and D co-infection and hepatitis D super-infection
Authors: Lars Frelin, Panagiota Maravelia, Rani Burm, Yi Ni, Gustaf Ahlén, Lieven Verhoye, Freya Van Houtte, Anna Pasetto, Stephan Urban, Philip Meuleman, Matti Sällberg
Journal: Journal of Hepatology (2022)
Characterization of bioengineered liver constructs using hepatoblast organoids (HBOs) and human liver extracellular matrix (ECM) 3D-platforms
Authors: Margarita Papatheodoridi, Katerina Zacharis, Carola Maria Morell, Elisabetta Caon, Luca Frenguelli, Andrew Hall, Ludovic Vallier, Krista Rombouts, Giuseppe Mazza, Massimo Pinzani
Journal: Journal of Hepatology (2022)
Gadoxetic acid-enhanced MRI-derived Functional Liver Imaging Score (FLIS) and spleen diameter provide complementary information for risk stratification in ACLD
Authors: Nina Bastati, Lucian Beer, Ahmed Ba-Ssalamah, Sarah Poetter-Lang, Raphael Ambros, Antonia Kristic, David Lauber, Lorenz Balcar, Katharina Pomej, Teresa Binter, Benedikt Simbrunner, Georg Semmler, Yesim Bican, Jacqueline C. Hodge, Thomas Wrba, Michael Trauner, Thomas Reiberger, Mattias Mandorfer
Journal: Journal of Hepatology (2022)
Andrographolide can potentially rescue unusable liver grafts by reducing fat content, enhancing mitochondrial function, and inhibiting Th1/Th17 immunity
Authors: Zhenlin Huang, Tengfei Si, Xiaohong Huang, Hanish Anand, Celine Filippi, Ragai Mitry, Anil Dhawan, Wayel Jassem, Zhengtao Wang, Nigel Heaton, Lili Ji, Yun Ma
Journal: Journal of Hepatology (2022)
Radiowater perfusion PETof the liver, and its value as a biomarker to discriminate between NAFLD and NASH, and activity and fibrosis grade
Authors: Olof Eriksson, Kerstin Heurling, Paul Hockings, Edvin Johansson, Alkwin Wanders, Håkan Ahlström, Lars Johansson, Johan Vessby, Fredrik Rorsman, Mark Lubberink
Journal: Journal of Hepatology (2022)
Prevalence, prognosis, clinical, biological and histological features of incidentally found hepatocellular carcinoma after liver transplantation
Authors: Emilie Kerstens, Samuele Iesari, Eliano Bonaccorsi, Laurent Coubeau, Géraldine Dahlqvist, Olga Ciccarelli, Bénédicte Delire
Journal: Journal of Hepatology (2022)
Addressing the heterogeneity of fibrosis in liver biopsy specimens with qFibrosis – a new paradigm for an old problem
Authors: David E. Kleiner, Pik Eu Jason Chang, Dean Tai, Elaine Chng, Yayun Ren, Feng Liu, Huiying Rao, Lai Wei, Arun Sanyal
Journal: Journal of Hepatology (2022)
Maximizing the potential of Cepheid, GeneXpert PCR rapid testing for hepatitis C through use of finger prick blood samples collected into EDTA capillary tubes
Authors: Anam Choudhry, Louise Davies, Nicki Palmer, Jade Davies, Bazga Ali, Rhys Oakley, James Plant, Louise Evans, Chinlye Chng, Helen Thompson-Jones, Lorraine Wall, Sarah Nicholas, Brendan Healy
Journal: Journal of Hepatology (2022)
Selective induction of macrophage RNF41 stimulates liver regeneration in hepatectomized healthy and fibrotic mice
Authors: Alazne Moreno-Lanceta, Mireia Medrano-Bosch, Yilliam Fundora, Meritxell Perramón, Jessica Aspas, Marina Parra-Robert, Sheila Baena, Constantino Fondevila, Elazer Edelman, Wladimiro Jiménez, Pedro Melgar-Lesmes
Journal: Journal of Hepatology (2022)
Integrating single-cell RNA and spatial transcriptomic data defines altered cell state in human liver fibrosis
Authors: Nigel Hammond, Sokratia Georgaka, Syed Murtuza-Baker, Ali Al-Anbaki, Elliot Jokl, Harry Spiers, Ajith Siriwardena, Varinder Athwal, Neil Hanley, Magnus Rattray, Karen Piper Hanley
Journal: Journal of Hepatology (2022)
ECC4703, a full thyroid hormone receptor beta (THRb) agonist, demonstrated excellent selectivity and liver targeting properties and improvement of plasma lipid, NAFLD acitivty score and fibrosis in NASH animial model
Authors: Jianfeng Xu, Zhao Yongliang, Julie Zhu, Jianfeng Xu, Jingye Zhou
Journal: Journal of Hepatology (2022)
Low levels of qHBsAg and tenofovir therapy are associated with successful treatment withdrawal in HBeAg negative chronic hepatitis B: results from spanish multicentric study
Authors: Anna Pocurull, Elena Hoyas, Manuel Rodríguez, Mireia Miquel, Clara Amiama Roig, Sergio Rodriguez-Tajes, Francisco Javier Garcia-Samaniego Rey, Emilio Suarez, Sabela Lens
Journal: Journal of Hepatology (2022)
Immune response and safety in standard and third dose SARS-CoV-2 vaccination in patients with autoimmune hepatitis on immunosupressive therapy, a prospective cohort study
Authors: Kristin Jorgensen, Adity Chopra, Joseph Sexton, Anne T Tveter, Johannes R. Hov, Ingrid Jyssum, Lise Sofie H. Nissen-Meyer, John T Vaage, Silje W Syversen, Guro L Goll, Fridtjof Lund-Johansen, Jørgen Jahnsen
Journal: Journal of Hepatology (2022)
ALT flares were linked to HBsAg reduction, seroclearance and seroconversion: interim results from a phase IIb study in chronic hepatitis B patients with 24-week treatment of subcutaneous PD-L1 Ab ASC22 (Envafolimab) plus nucleos (t)ide analogs
Authors: Guiqiang Wang, Yimin Cui, Yao Xie, Qianguo Mao, Qing Xie, Ye Gu, Xin-Yue Chen, Guoxin Hu, Yongfeng Yang, Jiajie Lu, Guizhou Zou, Qin Zhang, Lei Fu, Yongping Chen, Xiaolin Guo, Jinlin Hou, Yuemei Yan, Handan He, Jinzi Wu
Journal: Journal of Hepatology (2022)
Characterization and clinical correlation of the immune contexture in intrahepatic cholangiocarcinoma using multiplex immunohistochemistry
Authors: Simon Peter, Valery Volk, Charlotte Hoffmann, Melanie Bathon, Benjamin Goeppert, Thomas Longerich, Thomas Albrecht, Tanja Reineke-Plaaß, Friedrich Feuerhake, Arndt Vogel, Anna Saborowski
Journal: Journal of Hepatology (2022)
Five-years follow-up of cured HCV patients with or without cirrhosis under real-world interferon-free therapy
Authors: Robert Flisiak, Dorota Zarębska-Michaluk, Ewa Janczewska, Magdalena Rogalska, Ewa Karpińska, Tomasz Mikuła, Beata Bolewska, Jolanta Białkowska, Katarzyna Flejscher-Stępniewska, Krzysztof Tomasiewicz, Kornelia Karwowska, Monika Pazgan-Simon, Piekarska Anna, Hanna Berak, Tronina Olga, Aleksander Garlicki, Jerzy Jaroszewicz
Journal: Journal of Hepatology (2022)
Multidrug resistant bacterial infections after liver transplantation: prevalence, impact and associated risk factors
Authors: Rosa Martin-Mateos, Laura Martínez-Arenas, Ângela Carvalho-Gomes, Laia Aceituno, Valle Cadahía-Rodrigo, María Magdalena Salcedo, Ana Arias, Sara Lorente Perez, Aitor Odriozola, Javier Zamora, Marino Blanes, Óscar Len, Laura Benitez, Isabel Campos-Varela, Maria Luisa Gonzalez Dieguez, Diego Rojo Lázaro, Jesús Fortún, Antonio Cuadrado, Natalia Marcos Carrasco, Manuel Rodríguez-Perálvarez, Emilio Fabrega, Trinidad Serrano, Valentín Cuervas Mons, Manuel Rodríguez, Lluis Castells, Marina Berenguer, Javier Graus, Agustin Albillos
Journal: Journal of Hepatology (2022)
Real life efficacy and tolerability of Tenofovir alafenamde fumarate in liver transplant recipients: a multicenter study
Authors: Hale Gokcan, Suna Yapali, Murat Harputluoglu, Zeynep Melekoğlu Ellik, Pinar Gökçen, Haydar Adanir, Arif Mansur Cosar, Serdar Durak, Derya Ari, Shahin Mehdiyev, Elif Sitre Koç, Fatih Guzelbulut, Huseyin Alkim, Nergis Ekmen, Abdullah Emre Yıldırım, Yasemin Unsal, Tufan Teker, Digdem Ozer Etik, Sezgin Vatansever, Hatice Yasemin Balaban, Kamil Ozdil, Mehmet Arslan, Meral Akdogan Kayhan, Feyza Gunduz, Murat Kıyıcı, Sedat Boyacıoğlu, Halis Simsek, Nurdan Tozun, Dinc Dincer, Ramazan Idilman
Journal: Journal of Hepatology (2022)
Impact of artificial intelligence assistive tool on the histopathologic review of fibrosis in non-alcoholic steatohepatitis patients
Authors: Aileen Wee, Wei Qiang Leow, Gwyneth Soon, Elaine Chng, Dean Tai, Yayun Ren, Jia Ling Chong, Yee Chen Ng, Feng Liu, Lai Wei, Arun Sanyal
Journal: Journal of Hepatology (2022)
A small molecule chaperone for alpha-1 antitrypsin deficiency-associated liver disease reduces liver polymer burden in the PiZ mouse model
Authors: Britta Handyside, Lening Zhang, Katina Ngo, Ryan Murphy, Joseph Chen, Nicole Galicia, Olivia Gorostiza, Glenn Pacheco, Lin Xie, Donald Mackenzie, Heidi Jones, Brian Heglar, Bing Wang, Shripad Bhagwat, David Lomas, James Irving, Riccardo Ronzoni, Sherry Bullens, Sylvia Fong, Stuart Bunting
Journal: Journal of Hepatology (2022)
Yttrium-90 radioembolization versus drug-eluting beads chemoembolization for unresectable hepatocellular carcinoma: results from the TRACE phase 2 randomized controlled trial
Authors: Elisabeth Dhondt, Bieke Lambert, Laurens Hermie, Lynn Huyck, Peter Vanlangenhove, Anja Geerts, Xavier Verhelst, Maridi Aerts, Aude Vanlander, Frederik Berrevoet, Roberto Ivan Troisi, Hans Van Vlierberghe, Luc Defreyne
Journal: Journal of Hepatology (2022)
Hypertension and diabetes mellitus are associated with high FIB-4 index in a health checkup examination cohort without known liver disease
Authors: Shunsuke Sato, Hidehiko Kawai, Sho Sato, Hirohiko Iwasaki, Yuji Kita, Yuji Ikeda, Ayato Murata, Yuji Shimada, Takuya Genda
Journal: Journal of Hepatology (2022)
Yin Yang 1 promotes aggressive cell growth in high‐grade breast cancer by directly transactivating kinectin 1
Authors: Lin Gao, Wenbin Zhou, Ni Xie, Junying Qiu, Jingyi Huang, Zhe Zhang, Malin Hong, Jinquan Xia, Jing Xu, Pan Zhao, Li Fu, Yuwei Luo, Jing Jiang, Hui Gong, Jigang Wang, Yong Dai, Dixian Luo, Chang Zou
Journal: MedComm (2022)

Invasive cancer growth and metastasis account for the poor prognosis of high-grade breast cancer. Recently, we reported that kinectin 1 (KTN1), a member of the kinesin-binding protein family, promotes cell invasion of triple-negative breast cancer and high-grade breast cancer cells by augmenting the NF-κB signaling pathway. However, the upstream mechanism regulating KTN1 is unknown. Therefore, this functional study was performed to decipher the regulatory cohort of KTN1 in high-grade breast cancer. Bioinformatic analysis indicated that transcription factor Yin Yang 1 (YY1) was a potential transactivator of KTN1. High YY1 expression correlated positively with pathological progression and poor prognosis of high-grade breast cancer. Additionally, YY1 promoted cell invasive growth both in vitro and in vivo, in a KTN1-dependent manner. Mechanistically, YY1 could transactivate the KTN1 gene promoter. Alternatively, YY1 could directly interact with a co-factor, DEAD-box helicase 3 X-linked (DDX3X), which significantly co-activated YY1-mediated transcriptional expression of KTN1. Moreover, DDX3X augmented YY1-KTN1 signaling-promoted invasive cell growth of breast cancer. Importantly, overexpression of YY1 enhanced tumor aggressive growth in a mouse breast cancer model. Our findings established a novel DDX3X-assisted YY1-KTN1 regulatory axis in breast cancer progression, which could lead to the development novel therapeutic targets for breast cancer.
The ratio of Activin A and Follistatin-related gene allows prediction of posthepatectomy liver failure and postoperative morbidity in patients prior to liver surgery
Authors: Jonas Santol, David Pereyra, Steffanie Haegele, Daphni Ammon, Anita Pirabe, Philipp Jonas, Stefan Schuster, Sarang Kim, Toni Nguyen, Thomas Grünberger, Alice Assinger, Patrick Starlinger
Journal: Journal of Hepatology (2022)
Proteomic analysis of bile in the rat thioacetamide model reveals new mechanisms in human cholangiocarcinogenesis
Authors: Leticia Colyn, Gloria Álvarez-Sola, Maria U Latasa, Iker Uriarte, Jose Maria Herranz, Maria Arechederra, Juan Falcon-Perez, Antonio A Pineda, Andrea Casadei Gardini, Coral Barbas, Jesus M Urman, Bruno Sangro, Jesus Maria Banales, María Luz Martínez-Chantar, Jose Marin, Fernando Corrales, Maria Iraburu Elizalde, Francisco Javier Cubero, Carmen Berasain, Maite G Fernandez-Barrena, Matías A Avila
Journal: Journal of Hepatology (2022)
Unravelling the landscape of adipose tissue macrophages in human non-alcoholic fatty liver disease
Authors: Markus Boesch, Hannelie Korf, Rita Furtado Feio de Azevedo, Ellen Deleus, Matthias Lannoo, Lena Smets, Lukas Van Melkebeke, Marie Wallays, Tania Roskams, Pierre Bedossa, Andreas Lindhorst, Jef Verbeek, Thierry Voet, Alejandro Sifrim, Martin Gericke, Schalk van der Merwe
Journal: Journal of Hepatology (2022)
Untargeted lipidomics unveils a specific plasma signature of severe alcoholic hepatitis
Authors: Florent Artru, Stephen Atkinson, Francesca Trovato, Nikhil Vergis, Vishal C Patel, Salma Mujib, Anna Cavazza, Alexandros Pechlivanis, Ellen Jerome, Marc Zentar, Evangelos Triantafyllou, Elaine Holmes, Mark J W McPhail, Mark Thursz
Journal: Journal of Hepatology (2022)
Metabolomic analysis of bacterial infection markers in blood samples of patients with decompensated liver cirrhosis infused with the novel drug VS-01
Authors: Frank Uschner, Olaf Tyc, Wenyi Gu, Martin Schulz, Philip Ferstl, Katharina Staufer, Philipp Stoffers, Hans-Peter Erasmus, Johannes Masseli, Kai-Henrik Peiffer, Fabian Finkelmeier, Anita Pathil-Warth, Jörg Bojunga, Stefan Zeuzem, Meriam Kabbaj, Jonel Trebicka
Journal: Journal of Hepatology (2022)
Acquisition of positively charged amino acids in HBsAg C-terminus correlates with HBV-induced liver cancer, hampers HBsAg stability and secretion and promotes cell survival
Authors: Lorenzo Piermatteo, Luca Carioti, Gianluca Leoni, Leonardo Duca, Patrizia Saccomandi, Daniele Stella, Eleonora Andreassi, Ada Bertoli, Giuseppina Cappiello, Hervé Fleury, Pascale Trimoulet, Simona Francioso, Ilaria Lenci, Massimo Andreoni, Mario Angelico, Sandro Grelli, Antonella Minutolo, Loredana Sarmati, Claudia Matteucci, Francesca Ceccherini Silberstein, Valentina Svicher, Romina Salpini
Journal: Journal of Hepatology (2022)
EDP-514, a potent pangenotypic class II hepatitis B virus core inhibitor, demonstrates significant HBV DNA and HBV RNA reductions in a phase 1b study in viremic, chronic hepatitis B patients
Authors: Man-Fung Yuen, Wan-Long Chuang, Cheng-Yuan Peng, Rachel Wen-Juei Jeng, Wei-Wen Su, Ting-Tsung Chang, Chi-Yi Chen, Yao-Chun Hsu, Guy De Rosa La, Alaa Ahmad, Ed Luo, Annie Conery, Nathalie Adda
Journal: Journal of Hepatology (2022)
Intrahepatic transcriptional profiling demonstrates preclinical models of chronic hepatitis B resemble different stages of natural history in humans
Authors: Ricardo Ramirez, Anastasia Hyrina, Rudolf Beran, Stephane Daffis, Sarah Gilmore, Don Kang, Noé Axel Montanari, Nicholas Van Buuren, Li Li, Dara Burdette, Becket Feierbach, Andre Boonstra, Simon Fletcher
Journal: Journal of Hepatology (2022)
Efficacy and safety of bepirovirsen in patients with chronic hepatitis B virus infection on stable nucleos (t)ide analogue therapy: interim results from the randomised phase 2b B-Clear study
Authors: Man-Fung Yuen, Robert Plesniak, Seng Gee Lim, Keiji Tsuji, Gheorghe Diaconescu, Adrian Gadano, Ju Hyun Kim, Tarik Asselah, Hyung Joon Yim, Jeong Heo, Giuliano Rizzardini, Harry Janssen, Corneliu Petru Popescu, Diana Petrova, Alexander Wong, Nevin Indriz, Cristina Pojoga, Yasuhito Tanaka, Denis Gusev, Ewa Janczewska, Jennifer Cremer, Robert Elston, Tamara Lukic, Lauren Maynard, Stuart Kendrick, Punam Bharania, Fiona Campbell, Melanie Paff, Dickens Theodore
Journal: Journal of Hepatology (2022)
Recurring intrahepatic cholestasis of pregnancy presents with distinct changes in the gut microbiota
Authors: Hanns-Ulrich Marschall, Peidi Liu, Sara Malcus, Mattias Bergentall, Tanweer Khan, Anita Lövgren-Sandblom, Peter Malcus, Gun Lindell, Fredrik Backhed, Ewa Wiberg-Itzel, Helena Strevens
Journal: Journal of Hepatology (2022)
Hepatic recompensation according to Baveno VII criteria significantly reduces liver-related mortality in patients with decompensated alcohol-related cirrhosis
Authors: Benedikt Hofer, Benedikt Simbrunner, Lukas Hartl, Mathias Jachs, Lorenz Balcar, Rafael Paternostro, Philipp Schwabl, Georg Semmler, Bernhard Scheiner, Albert Stättermayer, Michael Trauner, Mattias Mandorfer, Thomas Reiberger
Journal: Journal of Hepatology (2022)
A report on the Australian Drug Induced Liver Injury Network: AusDILIN
Authors: Beverly Rodrigues, Stephen Bloom, Rohit Sawhney, Geoffrey Haar, Maria Bishara, Ayushi Chauhan, Paul Gow, Simone Strasser, Alan Wigg, Karl Vaz, Fadak Mohammadi, Amanda Nicoll
Journal: Journal of Hepatology (2022)