tbuckley/cabot-search huggingface dataset:
Adverse effect of additional weight on exercise against gravity in patients with chronic obstructive airways disease.
Authors: A J France
Journal: Thorax (1990)

<b>Aims:</b> To assess public opinion on the use of tissue samples from living adults and children for clinical research. <b>Methods:</b> A questionnaire study of 100 healthy volunteers (100% response rate) from a Newcastle NHS dental practice. The issues investigated were the types of tissues that individuals were prepared to donate for research, the type of research donors would be prepared to consent to, and attitudes to research on children’s tissues. <b>Results:</b> Eighteen per cent of the participants said that they would not give consent for research to be carried out on their tissues, 50% would not give consent for the donation of a child’s tissues. Only 26% of subjects said that they would give consent for research on genetic cloning compared with 82% for cancer research. Sex differences existed in the responses. <b>Conclusions:</b> Greater research attention needs to be given to public opinion on the use of tissue from living subjects for medical research to facilitate drafting of new legislation.
Erratum: Proteomic analysis of JAK2V617F-induced changes identifies potential new combinatorial therapeutic approaches
Authors: S Pearson, A J K Williamson, R Blance, T C P Somervaille, S Taylor, N Azadbakht, A D Whetton, A Pierce
Journal: Leukemia (2017)

Correction to: Leukemia (2017) 31, 2717–2725; doi:10.1038/leu.2017.143; published online 23 May 2017 This article was originally published under a CC BY-NC-ND 4.0 license, but has now been made available under a CC BY 4.0 license. The PDF and HTML versions of the paper have been modified accordingly.
Update: Influenza Activity—United States and Worldwide, 1993-94 Season, and Composition of the 1994-95 Influenza Vaccine
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The European Scientific Conference on Applied Infectious Disease Epidemiology (ESCAIDE) - selected papers from the conference 2008
Authors: Collective The ESCAIDE Scientific Committee
Journal: Eurosurveillance (2009)

Preview this article: The European Scientific Conference on Applied Infectious Disease Epidemiology (ESCAIDE) - selected papers from the conference 2008, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/14/43/art19377-en-1.gif
CASES IN MIDWIFERY: WITH REMARKS
Authors: T. Radford
Journal: BMJ (1856)

THE cases now publ'ished, are in continuation of a series which I commenced in the Provinzcial Medical and Sur- gicat Journal several years ago.CAsE vII.I am enabled to lay before the profession the following interesting case, through the kindncss of the brother of the late Dr. Hardy, who had promised to give it me previous to his death.Betty Wilcock, the subject of the following operation, was within a few weeks of completing her forty-ninth year, as appears from the baptismal register, dated October 26th, 1776.Her general health was good until within the last seven years, during which she experienced a dull heavy pain
Neonatology
Authors: R. James McKay, Jerold F. Lucey
Journal: New England Journal of Medicine (1964)

Bilirubin Metabolism and "Physiologic" JaundiceConsiderable progress has been made in the knowledge of bilirubin metabolism since the characterization of "direct" (conjugated) bilirubin as an ester glucuronide. The metabolic pathway involved in this hepatic conjugation is now well established and has been the subject of excellent reviews by Sherlock41 and Billing.42 Sherlock's diagrammatic representations of bilirubin metabolism (Fig. 1) and of the possible mechanisms of jaundice (Fig. 2) are reproduced here because they furnish a clear picture to serve as a reference point for the discussion to follow.41 It is interesting to re-examine current concepts of the etiology of physiologic . . .
Delayed Development of Hemispheric Dominance
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
FISH AS FOOD
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Giardiasis
Authors: Myron G. Schultz
Journal: JAMA (1975)

Physicians in the United States have a limited understanding of parasitic diseases. One reason for this deficiency is that the teaching of parasitic diseases has a low priority in American medical schools.<sup>1</sup>These diseases are often regarded as exotic entities of distant lands that rarely occur in our country. While it is true that the parasite burden of the American population is much lower than that of populations in developing countries, it is also true that virtually every parasitic disease known to man has been diagnosed in the United States in the past few years.<sup>2</sup>One of these diseases, giardiasis, has assumed great importance recently in the United States because of increasing numbers of indigenously acquired and imported cases. In the past, the intestinal flagellate<i>Giardia lamblia</i>has been regarded as a parasite of dubious pathogenicity. Experimental infection of man with cysts of<i>G lamblia</i>does not give
Diabetes and the risk of stroke. The Honolulu Heart Program
Authors: R. D. Abbott
Journal: JAMA (1987)

From 1965 to 1968, the Honolulu Heart Program began following up a cohort of men in a prospective study of cardiovascular disease. For this report, we examined the 12-year risk of stroke in 690 diabetic and 6908 nondiabetic subjects free of coronary heart disease and a history of stroke at study entry. In 12 years of follow-up, 62.3 per 1000 diabetic men and 32.7 per 1000 nondiabetic men experienced a stroke. The relative risk of thromboembolic stroke for those with diabetes compared with those without diabetes was 2.0 (95% confidence limits, 1.4 to 3.0). Although diabetes was usually associated with an atherogenic risk profile, control of hypertension, complicating myocardial infarction, and other risk factors failed to diminish the effect of diabetes on stroke. Among those without diabetes, the relative risk of thromboembolic stroke for those at the 80th percentile of serum glucose level compared with those at the 20th percentile (199 vs 115 mg/dL [11.0 vs 6.4 mmol/L]) was 1.4 (95% confidence limits, 1.1 to 1.8). In the nondiabetic sample, the relative risk of thromboembolic stroke for those with glucosuria compared with those without glucosuria was 2.7 (95% confidence limits, 1.6 to 4.5). There was no association between diabetes, or measures of glucose intolerance, and hemorrhagic stroke. We conclude that diabetes, even in a possibly undiagnosed subset of hyperglycemic individuals, imparts an additional independent risk of stroke unexplained by clinically measured risk factors. (<i>JAMA</i>1987;257:949-952)
Pneumocystis carinii pneumonia: a major complication of immunosuppressive therapy in patients with Wegener's granulomatosis.
Authors: F Vincent, T A Bensoussan
Journal: American Journal of Respiratory and Critical Care Medicine (1995)

"Pneumocystis carinii pneumonia: a major complication of immunosuppressive therapy in patients with Wegener's granulomatosis.." American journal of respiratory and critical care medicine, 152(4), p. 1424
Solitary Metastases
Authors: Joseph E. Whitley
Journal: JAMA (1969)

This brief, interesting text presents a useful pragmatic insight into the concept of solitary metastases. The authors' stated preoccupation is the curability of metastatic disease. The first and last chapters are subtitled "Illusion Versus Reality." The intervening chapters are oriented about individual sites where metastases are commonly encountered, and there is a single chapter on "The Formation of a Metastasis." Each of the six site chapters is introduced with statistical information about metastasis to the organ, the clinical problems of diagnostic work-up and patient selection, treatment techniques and results, and the authors' own radiotherapeutic techniques and results. The formation of metastasis is considered from the theoretical basis of cause and mechanism as well as factors influencing growth. A brief sketch of animal and human data in this area is presented. Each chapter has numerous references (285 total) with publication dates which extend from 1888 to 1967. The principal audience for
Henry Fuseli, nightmare, and sleep paralysis
Authors: J. M. Schneck
Journal: JAMA (1969)

Henry Fuseli painted "The Nightmare" in 1781 (see cover). The picture is dramatic, and it has been used to illustrate articles in professional journals. I believe the painting has several features of sleep paralysis, and my remarks are so directed. Fuseli was an Anglo-Swiss painter and author, born in Zurich, Feb 7, 1741.<sup>1</sup>His father was Johann Caspar Füssli, a court painter and town clerk. Henry Fuseli was educated at the Collegium Carolinum in Zurich. He started to study theology but left home because of problems stemming from a political publication. He went to Berlin, and then in 1764 to London on the recommendation of the British ambassador. The following year he translated into English J. J. Winckelmann's<i>Reflections on the Painting And Sculpture of the Greeks</i>. In 1770 he went to Italy to become a painter, having been encouraged by Sir Joshua Reynolds. He sent his first work
Outbreak of Syphilis Among Men Who Have Sex With Men--Southern California, 2000
Journal: JAMA (2001)

Syphilis is a sexually transmitted disease (STD) caused by infection with the spirochete Treponema pallidum, and like other genital ulcer diseases, syphilis enhances the transmission of human immunodeficiency virus (HIV). During the 1990s, syphilis occurred predominantly among heterosexual blacks in the South and in large cities. However, recent outbreaks of syphilis have occurred among men who have sex with men (MSM). A large syphilis outbreak occurred among MSM during January-July 2000 in southern California. During the outbreak period, the proportion of primary and secondary (P&S) syphilis cases among MSM increased to 51% from 26% for the same period in 1999. This report summarizes the findings of an investigation of this syphilis outbreak, which indicate a substantial increase in the number of syphilis cases among MSM, many of whom are HIV-positive. These data suggest that concern about HIV infection may be declining among MSM and emphasize the importance of strengthening efforts to prevent HIV infection in this population in the United States.
Hazards of Gas and Air in Obstetrics
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Education "effect' in hypertension. Data on possible environmental poisons. Penicillin alternatives in gonorrhea
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ANESTHESIA VERSUS HOMICIDE BY NEGLECT.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
From the Centers for Disease Control and Prevention. Recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
'Lp(a)' joins other serum cholesterol lipoproteins as risk determinant
Authors: B. Merz
Journal: JAMA (1989)

ANOTHER LIPOPROTEIN has been added to the roster of serum cholesterol components to be reckoned with. According to recent reports, serum concentrations of lipoprotein(a), often referred to as "Lp(a)," may be just as important as those of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) in determining risk for coronary heart disease. At a recent American Heart Association science writers' seminar in Monterey, Calif, John J. Albers, PhD, reported that a study of men with coronary disease indicated that Lp(a) was a better predictor of severity than either LDL or HDL. Albers, who is research professor of medicine and pathology at the University of Washington School of Medicine, Seattle, said that he and colleague B. Greg Brown, MD, found that Lp(a) levels varied directly with degree of arterial stenosis, with 27% of more than 200 patients with extensive three-vessel disease having Lp(a) levels in the 95th percentile (1.25 mm/L or 48
Abstract 19030: High Mortality in Cardiomyopathy Patients Heterozygous for the CFTR ΔF508 Cystic Fibrosis Mutation
Authors: Barry London, Ryan Boudreau, Indrani Halder, Andres Vargas-Estrada, Alejandro Comellas, Frances L Johnson, Joseph Zabner, Rebecca A Gutmann, Heather L Bloom, Samuel C Dudley, Patrick T Ellinor, Alaa Shalaby, Raul Weiss
Journal: Circulation (2015)

Introduction: Cystic fibrosis is among the most common inherited disorders, with ∼ 3% of Caucasians being heterozygous for the common CFTR ΔF508 mutation. Cardiomyopathy is a major cause of morbidity and mortality. While a small preliminary study suggested that cardiomyopathy patients heterozygous for the CFTR ΔF508 mutation have poorer outcomes, the finding has not been replicated and it is not known whether the poor outcomes are related to sudden death and/or heart failure progression. Methods: We screened 1347 Caucasian cardiomyopathy subjects (EF 21%, 82% male, 75% ischemic) with implantable cardioverter defibrillators (ICDs) from the prospective, multicenter, NIH-funded Genetic Risk Assessment of Defibrillator Events (GRADE) study. CFTR ΔF508 alleles were discriminated by real time fluorescence PCR. GRADE subjects were followed for up to 5 years to the primary endpoint of freedom from appropriate ICD shocks and the secondary endpoints of death and death/heart transplant/VAD placement. The results were compared by genotype using Kaplan-Meier analysis and Log Rank testing. Results: Genotyping revealed 33 CFTR ΔF508 heterozygotes (allele frequency 2.4%). ΔF508 carriers were older (68 vs 64 yrs, p=0.03); more likely to be diabetic (55 vs 34%, p=0.02), to have had an MI (77 vs 57%, p=0.02), and to have a RBBB on ECG (18 vs 7%, p=0.03); and had lower EFs (19 vs 21%, p=0.01). CFTR ΔF508 carriers had markedly higher rates of death (HR&gt;2; p&lt;0.001) and death/VAD/transplant (p=0.004), with no difference in appropriate ICD shocks (Figure). Conclusion: We have confirmed that carrying one CFTR ΔF508 allele is associated with an increased mortality in cardiomyopathy patients, and that this is likely not due to increased arrhythmic death. These findings may have implications for the treatment of this high risk heart failure subgroup. Future studies are needed to determine whether the increased mortality stems from a cardiac and/or pulmonary etiology.
Current Comment
Journal: JAMA (2018)

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