tbuckley/cabot-search huggingface dataset:
PROSTATE-CANCER METASTASIS SIMULATING BREAST CANCER
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Partnerships in medical education
Authors: C. J. Martini
Journal: JAMA (1991)

We frequently hear that the United States has one of the best—if not<i>the</i>best—medical education systems in the world. However, with the same frequency, detractors complain about the system's resistance to improvements and change. As Alvin Tarlov, MD,<sup>1</sup>recently observed, from a sociologic perspective, medical institutions may reach a level of maturity that leaves them paralyzed and unable to reform themselves. After years of experimentation and discussion, modifications are just now being made to a stable and entrenched medical education establishment, notorious for rejecting innovation. The following discussion is intended as a reminder of critical issues that have attracted the interest of the medical education community during the past year. Some of the very factors that make the US system successful also deter change. A conglomerate of connected but relatively independent components, medical education thrives on the American traditions of decentralization and autonomy. But national efforts, such as
Silicone treatment of partial lipodystrophy
Authors: T. D. Rees
Journal: JAMA (1974)

Partial lipodystrophy, a symmetrical wasting of adipose tissue from the face and proximal part of the body, is a rare disease of undetermined etiology. Despite our ignorance of the underlying pathophysiology, the clinical manifestations are entirely reversible with liquid silicone. Percutaneous injections into the subcutaneous space of the wasted area effectively restore soft tissue contours and mask the absence of adipose tissue. (<i>JAMA</i>230:868-870, 1974)
Bureau of Investigation
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Die Diathermie.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Optimal liver metabolism and proliferation require the tight junction protein claudin-3
Authors: Felix Alexander Baier, Daniel Sanchez-Taltavull, Fadi Jebbawi, Adrian Keogh, Nicolas Melin, Mariana Mota Castro Dias, Urban Deutsch, Britta Engelhardt, Mikio Furuse, Adolfo Odriozola, Benoit Zuber, Daniel Candinas, Deborah Stroka
Journal: Journal of Hepatology (2020)
Senate Committee on Labor and Human Resources Approves NIH Reauthorization Bill
Journal: JNCI Journal of the National Cancer Institute (1988)

Journal Article Senate Committee on Labor and Human Resources Approves NIH Reauthorization Bill Get access JNCI: Journal of the National Cancer Institute, Volume 80, Issue 6, 18 May 1988, Page 390, https://doi.org/10.1093/jnci/80.6.390 Published: 18 May 1988
Exanthem due to contact allergen (benzoin) absorbed through skin
Authors: D. A. Spott
Journal: JAMA (1970)

A student developed acute eczematous contact dermatitis in response to the application of tincture of benzoin to the skin under a cast. This was followed within 48 hours by the appearance of generalized noneczematous exanthem. Analysis led to the conclusion that absorption of benzoin through the skin was responsible for both the contact dermatitis and the exanthem. Patch tests demonstrated an eczematous reaction to benzoin, with cross sensitivity extending to the gums of myrrh, locust, galbanum, gamboge, and olibanum.
Syphilis Rates Increase, Especially Among Men
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
La Méthode Psychanalytique.
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Adverse Health Conditions and Health Risk Behaviors Associated With Intimate Partner Violence—United States, 2005
Journal: JAMA (2008)

Intimate partner violence (IPV) is defined as threatened, attempted, or completed physical or sexual violence or emotional abuse by a current or former intimate partner. IPV can be committed by a spouse, an ex-spouse, a current or former boyfriend or girlfriend, or a dating partner. Each year, IPV results in an estimated 1,200 deaths and 2 million injuries among women and nearly 600,000 injuries among men. In addition to the risk for death and injury, IPV has been associated with certain adverse health conditions and health risk behaviors. To gather additional information regarding the prevalence of IPV and to assess the association between IPV and selected adverse health conditions and health risk behaviors, CDC included IPV-related questions in an optional module of the 2005 Behavioral Risk Factor Surveillance System (BRFSS) survey. This report describes the results of that survey, which indicated that persons who report having experienced IPV during their lifetimes also are more likely to report current adverse health conditions and health risk behaviors. Although a causal link between IPV and adverse health conditions cannot be inferred from these results, they underscore the need for IPV assessment in health-care settings. In addition, the results indicate a need for secondary intervention strategies to address the health-related needs of IPV victims and reduce their risk for subsequent adverse health conditions and health risk behaviors.
Animal experiments
Authors: H. Hewitt
Journal: BMJ (1982)

goodbyes are said, the dying person may refuse to receive any more visitors or open letters."I tried to consider the process of dying from the point of view of the survivors and, using Keats as an example, to emphasise the importance for them of the phase during which the dying person comes to say farewell.This phase, which precedes the "detachment" of Kubler- Ross, may have an influence on the health and wellbeing of the bereaved.I suggested that the physician may have a role in helping the patient to realise the need to say goodbye.
Hepatic iron deposition during ribavirin therapy of chronic hepatitis C , Jr. Mt. Sinai Med. Ctr., New York, NY; 1ULSS 19-Cittadella Hosp., Padoua, Italy; 2Univ. of Southern California, Los Angeles, CA; Univ. of Florida, Gainsville, FL; 4Georgetown Univ. Med. Ctr., Washington, DC; 5Veterans Affairs Med. Ctr., Washington, DC
Journal: Hepatology (1995)

Basándonos en los datos ya conocidos sobre el comportamiento de los mecanismos de transmisión del sonido, creamos un modelo que reproduce la actividad mecánica del oído medio, utilizando el método de los elementos finitos. Diseñamos un modelo computadorizado que simula el comportamiento biomecánico de la membrana timpánica y la cadena osicular. Centramos el interés de la investigación en sus posibles aplicaciones clínicas, pudiendo introducir en el modelo las variables necesarias para la simulación de distintas situaciones: perforaciones timpánicas, fijaciones osiculares, interrupciones de la cadena, etc. Suministrando al programa simulador las características de la lesión creamos un modelo virtual sobre el que podemos valorar la hipoacusia existente y las posibilidades terapéuticas. Realizamos este modelo 3-D de membrana timpánica, martillo, yunque y estribo considerando su forma, peso, densidad, módulo de Young (N/m2) y coeficiente de Poisson, para las diferentes partes del sistema. Mostramos también la modelización de los elementos de unión entre los diferentes elementos tímpano-osiculares, incluidos músculos y ligamentos.Based on known data about the behavior of the sound transmission mechanism, we generate a model that reproduces the real mechanics of the middle ear by the finite elements method in the most exact manner possible. We designed a computerized model to simulate the biomechanic behavior of the ear drum / ossicular chain. The investigation focused on a possible clinical application, given that the variables neccesary for simulation of several conditions can be introduced in our model: tympanic perforation, fixation of the ossicular chain, chain interruption, etc. Introducing the characteristics of the lesion virtually in a simulator program maket is possible to reach conclusions about the conductive hypoacusis created and about therapeutic possibilities. The 3-D modelling of the tympanic membrane, malleus, incus and stapes is presented, considering form, weight, density, Young’s module (N/m2) and Poisson coefficient for the different parts of each ossicle. The modeling of the union of the different tympanic-ossicular elements, including muscles and ligaments, is also shown.
Incorrect Data in Abstract, Text, and Figure
Authors: Thomas Agoritsas, Arnaud Merglen, Gordon Guyatt
Journal: JAMA (2017)

US Preventive Services Task Force; Kirsten Bibbins-Domingo, PhD, MD, MAS; David C. Grossman, MD, MPH; Susan J. Curry, PhD; Karina W. Davidson, PhD, MASc; John W. Epling Jr, MD, MSEd; Francisco A. R. García, MD, MPH; Matthew W. Gillman, MD, SM; Diane M. Harper, MD, MPH, MS; Alex R. Kemper, MD, MPH, MS; Alex H. Krist, MD, MPH; Ann E. Kurth, PhD, RN, MSN, MPH; C. Seth Landefeld, MD; Carol M. Mangione, MD, MSPH; Douglas K. Owens, MD, MS; William R. Phillips, MD, MPH; Maureen G. Phipps, MD, MPH; Michael P. Pignone, MD, MPH; Albert L. Siu, MD, MPH
Improved survival for stage IV melanoma from an unknown primary site
Authors: C. C. Lee, M. B. Faries, L. A. Wanek, D. L. Morton
Journal: Journal of Clinical Oncology (2008)

9031 Background: We and others have observed a survival advantage for nodal metastasis from an unknown versus a known primary melanoma (MUP versus MKP). Although nodal metastasis in the setting of MUP has been attributed to precursor nevus cells in a lymph node, we believe that immune-induced regression of the primary is more likely. To test this hypothesis, we examined the prognostic impact of MUP in patients with melanoma metastatic to distant sites. Methods: We reviewed prospectively acquired data for 2,247 patients diagnosed with AJCC stage IV melanoma at our cancer center between 1971 and 2005. Cox regression analysis in a multivariate model identified prognostic factors significant for survival. MUP and MKP patients were then matched by significant covariates. Overall survival (OS) was estimated by Kaplan-Meier method and compared by log-rank analysis. Results: There were 1,849 MKP and 398 MUP patients. Multivariate analysis identified known/unknown primary (HR=1.141, P=0.0316) and five other significant covariates: age (HR=1.148, P=0.0069), sex (HR=1.17, P=0.0012), site of metastasis (HR=1.336, P<0.0001), number of different metastatic sites (HR=1.303, P<0.0001), and decade of diagnosis (HR=0.713, P<0.0001). Matching of MUP and MKP by these significant covariates yielded 392 matched pairs. Median and 5-year OS rates were significantly greater for MUP patients than for all matched MKP patients (P=0.0002) or for MKP patients matched by M1 category (for M1b and M1c) or number of metastatic sites (Table). Conclusions: The significant survival advantage for MUP compared to MKP in stage IV melanoma suggests a systemic effect. We hypothesize that the clinical absence of a known primary is the result of a strong and durable endogenous antitumor response that alters disease biology and thereby improves clinical outcome. Immunologic studies to identify the nature of this endogenous response warrant further investigation. Variable N Pairs MKP Median Survival (months) MKP 5-year Survival (%) MUP Median Survival (months) MUP 5-year Survival (%) P Matched Outcome 392 11 10+3 16 18+4 0.0002 M1 Category M1a 26 16 18+15 20 12+12 0.4109 M1b 95 13 9+6 19 21+9 0.0155 M1c 271 10 10+4 15 18+5 0.0009 # Sites 1 170 14 11+5 19 26+7 0.0009 2 222 10 10+4 13 12+5 0.0361 MUP=melanoma of unknown primary; MKP=melanoma of known primary No significant financial relationships to disclose.
Effect of Dibutylnitrosamine and Saccharin on Glutamyl Transpeptidase-Positive Foci and Liver Cancer
Authors: Michael A. Pereira, Sydna L. Herren, Alfred L. Britt
Journal: Environmental Health Perspectives (1983)

Consistent with the proposed precursor relationship of GGTase-positive foci to hepatocarcinogenesis, the induction of foci by DBN was associated with the induction of hyperplastic nodules and hepatocellular carcinoma and the concurrent administration of sodium saccharin in the diet with DBN in the drinking water increased the tumorigenic response in the liver to DBN.
Outcomes of a Clinician-Directed Protocol for Discontinuation of Complement Inhibition Therapy in Atypical Hemolytic Uremic Syndrome
Authors: Noor Dhaliwal, Sarah Hussain, Harshvardhan Upreti, Evan M Braunstein, Xuan Yuan, Alison R. Moliterno, Robert Brodsky, Shruti Chaturvedi
Journal: Blood (2020)
Experimental Atherosclerosis
Authors: Robert D. Coye
Journal: JAMA (1965)

In this relatively small book, the author makes a surprisingly complete presentation of the experimental evidence dealing with the factors that produce atherosclerosis, chiefly in the rabbit. Those factors which he discusses at length are lipemia, arterial injury, and thrombosis. The presentation is oriented largely to the morphology of the lesions, but at the same time the chemical and physiological aspects are not neglected. The volume also contains short sections which deal with human atherosclerosis, the care of laboratory animals, and some unsolved problems in atherosclerosis research. The writing is quite good—direct, clear, and at times even entertaining. The reader gathers the impression not only that the author knows a great deal about this field but also that he judges fairly the relative merits of the frequently conflicting bits of evidence. There are numerous references and a sizable number of figures and illustrations which vary considerably in quality.
Surrender
Authors: Richard Allen
Journal: Annals of Internal Medicine (2015)

On Being a Doctor21 July 2015SurrenderRichard Allen, MD, MPHRichard Allen, MD, MPHFrom Utah Healthcare Institute, Salt Lake City, Utah.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M15-0023 Audio Reading - “Surrender” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Surrender," by R. Allen. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail "Bob" is not a very Japanese name. That was my first clue to his westernization."Welcome to our home, doctor," he said in a thick accent. However, he spoke rapidly, suggesting decades of English. He gave a deep, respectful bow as I mentally assessed his age. Seventy-five at most, he had migrated here as a little boy just after the war."Konnichiwa," I responded with a short bow in my best restaurant Japanese. I worked at the downtown Mikado during my teens. That was at least 30 years after the war."Oh, your Japanese so good," he said, as they ... Author, Article, and Disclosure InformationAffiliations: From Utah Healthcare Institute, Salt Lake City, Utah.Corresponding Author: Richard Allen, MD, MPH, Utah Healthcare Institute, 1250 East 3900 South, Suite 260, Salt Lake City, UT 84124; e-mail, [email protected]org. PreviousarticleNextarticle Advertisement Audio Reading - “Surrender” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Surrender," by R. Allen. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 21 July 2015Volume 163, Issue 2Page: 145-146KeywordsNursesPalliative careParalysisQuality of lifeRashesSafetySaltsSub-specialty careTeaWalking ePublished: 21 July 2015 Issue Published: 21 July 2015 Copyright & PermissionsCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Susceptibility of p53-Deficient Mice to Induction of Mesothelioma by Crocidolite Asbestos Fibers
Authors: Jean M. Marsella, Brenda L. Liu, Charles A. Vaslet, Agnes B. Kane
Journal: Environmental Health Perspectives (1997)

Exposure of mesothelial cells to asbestos fibers in vitro has been shown to induce DNA damage mediated by oxidants.An early cellular response to DNA damage is increased expression of the p53 protein.This protein induces transcription of genes that activate cell cycle checkpoints or induce apoptosis.A murine mesothelial cell line that spontaneously acquired a point mutation in the p53 gene shows increased sensitivity to DNA damage induced by crocidolite asbestos fibers.It is hypothesized that p53-deficient mice will show increased sensitivity to the genotoxic effects of asbestos and accelerated development of malignant mesotheliomas.
Greater New York and New England Chapters, the Society of Nuclear Medicine 17th Annual Northeast Regional Scientific Session 9997ractsOctober 31–November 2, 2003–Mystic, Connecticut
Journal: Clinical Nuclear Medicine (2004)

Greater New York and New England Chapters, the Society of Nuclear Medicine 17th Annual Northeast Regional Scientific Session Abstracts October 31—November 2, 2003—Mystic, Connecticut: PDF Only