POS0079-HPR PATIENT-REPORTED OUTCOMES MEASURES FOR SYSTEMIC LUPUS ERYTHEMATOSUS: AN EXPERT DELPHI CONSENSUS TO GUIDE IMPLEMENTATION IN ROUTINE CARE
Authors: I. Castrejon, L. Cano Garcia, M. J. Cuadrado Lozano, J. Borrás, M. Galindo-Izquierdo, T. C. Salman Monte, C. Amorós, C. San Román Gutiérrez, A. Muñoz
Journal: Annals of the Rheumatic Diseases (2023)

<h3>Background</h3> Patient-reported outcome measures (PROMs) are useful to incorporate the patient's perspective in the disease decision-making process, which has been identified as one of the main challenges in the management of Systemic Lupus Erythematosus (SLE) patients [1,2]. <h3>Objectives</h3> To establish expert recommendations to incorporate PROMs on the current management and empowerment of patients with SLE. <h3>Methods</h3> After a scoping review of the literature and structured interviews with SLE patients (n=9) a survey-based questionnaires were developed by a scientific committee (5 rheumatologists, 1 H. pharmacist and 1 nurse). Using a Delphi approach, consensus was reached regarding the role of PROMs in SLE patients, strategies and more feasible measures to be incorporated in routine care. <h3>Results</h3> A total of 59 experts participated: 51% rheumatologist, 17% internists, 8% nephrologist, 3% dermatologist, and 20% other health professionals in rheumatology (nurses, pharmacists, and psychologists). Around 50% of participants were women, with a mean of 18 years of experience managing SLE patients. Panelists agreed on the following recommendations: incorporating the patient's perspective through the use PROMs (83%), utility of a digital tool to collect PROMs connected to the electronic medical record (85%), incorporating other health professionals to support patients to complete PROMs (77%), a multidisciplinary approach to improve specialists' interaction/coordination (79%), and incorporating H. pharmacists to improve medication management (70%). Panelists agreed that PROMs can facilitate patient participation in decision-making with an adherence to treatment improvement (72%). Consensus was reached on the appropriateness of the following PROMs in routine care: a Visual Analog Scale (VAS) 0-100 for pain (83%), fatigue (73%), and patient global assessment (76%), the Functional Assessment of Chronic Illness Therapy Fatigue (FACIT) for fatigue (75%), and the Lupus Impact Tracker (LIT) (75%) to evaluate health-related quality of life. <h3>Conclusion</h3> Strategies to promote a holistic and integrated approach including the creation of multidisciplinary teams and the incorporation of patient's perspective using PROMs, such as VAS-pain, VAS-fatigue, FACIT-Fatigue, VAS-PGA and LIT, are recommended to improve SLE management in routine care. <h3>References</h3> [1]Sloan M, et al. Rheumatol Adv Pract. 2020;4(1):rkaa006. [2]Piga M, et al. J Clin Med. 2021;10(2). <h3>Funding</h3> This project has been funded by GSK. <h3>Acknowledgements</h3> We thank FELUPUS and the following experts: E Morales, A Martín, A Ávila, M Uriol, L Quintana, E Ramírez, P Lopez, T Palanques, A Gilabert, E Chavarría, C Mouriño, C Martin, S Garcia, P Garcia, M Ferreiro, R Serrano, C Domínguez, N Ortego, J Callejas, G Espinosa, L Pallarés, A Robles, D Bellido, J Barbado, C Romero, A Martin, I Rodriguez, I Altabás, C Pego, A Aragón, E Trujillo, I Rua, M Garcia, A Fernádez, J Calvo, C Marras, A Garcia, V Torrente, C Moriano, M Aguirre, M Freire, R Blanco, L Riancho, J Martínez, P Navarro, T Cobo, A Domínguez, C Valdés, J Antón, J Andreu, O Sánchez, B Tejera, G Mercadal, M Comellas, I Cabezas. <h3>Disclosure of Interests</h3> Isabel Castrejon Consultant of: GSK, Laura Cano Garcia Consultant of: GSK, Maria Jose Cuadrado Lozano Consultant of: GSK, Joaquín Borrás Consultant of: GSK, María Galindo-Izquierdo Consultant of: GSK, Tarek Carlos Salman Monte Consultant of: GSK, Carlos Amorós Employee of: GSK, Carmen San Román Gutiérrez Employee of: GSK, Alejandro Muñoz Consultant of: GSK.