tbuckley/cabot-search huggingface dataset:
Biochemical Test To Help Diagnose Aortic Dissection
Journal: Annals of Internal Medicine (2000)

Summaries for Patients3 October 2000Biochemical Test To Help Diagnose Aortic DissectionSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-133-7-200010030-00007 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?The aorta is the largest blood vessel, bringing blood from the heart to the rest of the body. Aortic dissection is a potentially deadly condition in which the muscular wall of the aorta becomes torn. Diagnosing aortic dissection quickly and accurately is very important since this condition needs to be treated immediately. Unfortunately, the condition can be difficult to diagnose. Doctors ordinarily use special imaging studies to diagnose aortic dissection, but these studies are not always immediately available and can be time-consuming. The authors of this study have ... Author, Article, and Disclosure InformationThe summary below is from the full report titled “Diagnostic Implications of Elevated Levels of Smooth-Muscle Myosin Heavy-Chain Protein in Acute Aortic Dissection. The Smooth Muscle Myosin Heavy Chain Study.” It is in the 3 October 2000 issue of Annals of Internal Medicine (volume 133, pages 537-541). The authors are T Suzuki, H Katoh, Y Tsuchio, A Hasegawa, M Kurabayashi, A Ohira, K Hiramori, Y Sakomura, H Kasanuki, S Hori, N Aikawa, S Abe, C Tei, Y Nakagawa, M Nobuyoshi, K Misu, T Sumiyoshi, and R Nagai.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoDiagnostic Implications of Elevated Levels of Smooth-Muscle Myosin Heavy-Chain Protein in Acute Aortic Dissection: The Smooth Muscle Myosin Heavy Chain Study Toru Suzuki , Hirohisa Katoh , Yasuhiro Tsuchio , Akira Hasegawa , Masahiko Kurabayashi , Atsushi Ohira , Katsuhiko Hiramori , Yasunari Sakomura , Hiroshi Kasanuki , Shingo Hori , Naoki Aikawa , Satoshi Abe , Chuwa Tei , Yoshihisa Nakagawa , Masakiyo Nobuyoshi , Kazuhiko Misu , Tetsuya Sumiyoshi , and Ryozo Nagai Metrics 3 October 2000Volume 133, Issue 7Page: I-50KeywordsAortaBloodBlood vesselsHeartHematologic testsLongitudinal studiesMyocardial infarctionMyosinsProteinsSmooth muscles ePublished: 3 October 2000 Issue Published: 3 October 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
PLoS Medicine Issue Image | Vol. 8(4) April 2011
Journal: PLoS Medicine (2011)

In the April editorial, the PLoS Medicine Editors argue that the publication of new evidence of the complicity of medical personnel in torture at Guantánamo Bay (GTMO) should bolster calls for further investigation into the role of medical staff at the prison. The new evidence is presented in research by Vincent Iacopino and Stephen Xenakis, in which the review of case records and legal documents of nine individuals imprisoned at Guantánamo Bay suggest that medical personnel assigned to the Department of Defense neglected to act on and/or concealed medical evidence of torture. Image Credit: United States Department of Defense at Wikimedia Commons
Therapeutic use of albumin
Authors: M. R. Alexander
Journal: JAMA (1979)

Increasing use of normal human serum albumin may be contributing to the rising cost of medical care. To investigate whether albumin is extensively overused or abused, a study of the quality of albumin use was conducted in a Veterans Administration Hospital. Specific criteria for appropriate use were developed using guidelines defined at a national symposium. A review of use during a three-month period showed that surgery patients received 91% of the albumin administered during that period; of the total amount administered, 41% was used inappropriately; the decision to administer albumin to patients undergoing surgery appeared to be correct only 29% of the time; and an estimated $40,000 was spent on inappropriately used albumin at this hospital in 1977. (<i>JAMA</i>241:2527-2529, 1979)
Role of L-thyroxine in nuclear thyroid hormone receptor occupancy and growth hormone production in cultured GC cells
Journal: Journal of Clinical Investigation (1991)

In the Abstract, line 15 read: Nuclear free T3 was 3-6-fold greater than medium free T3 and medium free T4 was 12-19-fold greater than medium free T4.It should read: Nuclear free T3 was 3-6-fold greater than medium free T3 and nuclear free T4 was 12-19-fold greater than medium free T4.
Gobelin's history of medicine and science
Authors: W. C. Gibson
Journal: JAMA (1968)

The acquisition of a modern Gobelin tapestry (see cover picture) by the University of British Columbia has caused some excitement among members of our profession addicted to history. One of Canada's best-known philanthropists, P. A. Woodward, the prime mover in the Health Science Centre in Vancouver, has recently presented to the Memorial Room of his Bio-Medical Library a colorful Gobelin measuring 16 feet by 11 feet, depicting some forty figures famous in the annals of medicine, physics, chemistry, biology, astronomy and philosophy (Figure). The tapestry which has just arrived in Canada was produced by the head of the Gobelin house, Monsieur J. Cochery, in Paris in 1948, and is the artist's proof for one commissioned for the Thesis Room of the Sorbonne. Of particular interest to medical readers will be those depicted in the tapestry, who were connected with the clinical and basic medical sciences. One might commence a brief
Ascorbic acid inhibits chemically induced uroporphyria in ascorbate-requiring rats*1
Authors: P SINCLAIR
Journal: Hepatology (1995)

Ascorbate was previously shown to suppress accumulation of uroporphyrin (URO) in cultured chick embryo hepatocytes and to competitively inhibit microsomal oxidation of uroporphyrinogen catalyzed by cytochrome P4501A2. Here we used the Osteogenic Disorder Shionogi (ODS) mutant rat, which cannot synthesize ascorbic acid, to examine the in vivo effect of ascorbic acid on hepatic URO accumulation caused by treatment with 3-methylcholanthrene (MC) and 5-aminolevulinate (ALA). Female mutant rats maintained on three levels of dietary ascorbate (15,200, and 800 ppm) were treated for a total of 24 days. On the 11th and 16th days, rats were administered 3-methylcholanthrene, and 5-amino-levulinate was present continuously in the drinking water from day 14. Hepatic URO accumulated at the two lowest ascorbate levels, but not at 800 ppm ascorbate. The latter dose produced normal hepatic ascorbate levels. Plasma ascorbate levels were proportional to the hepatic values. Male rats also accumulated URO at the low dietary dose of ascorbic acid. The methylcholanthrene-induced increase in microsomal levels of CYP1A1 and CYP1A2, total cytochrome P450, and activities of uroporphyrinogen oxidation and ethoxyresorufin deethylase were not affected by the dietary level of ascorbate. Neither male nor female Fischer 344 rats accumulated URO when treated with the MC/ALA regime. Hepatic ascorbate concentrations in these rats were five-fold to seven-fold higher than they were in mutant rats that developed uroporphyria on 150 ppm dietary ascorbate. In ODS rats fed ascorbate at 90 but not 900 ppm in the diet, hexachlorobenzene caused hepatic URO accumulation, indicating that the effect of ascorbic acid is not unique to the regimen using methylcholanthrene. These results are consistent with a role for ascorbate in preventing chemically induced URO accumulation and suggest that ascorbate might have a role in preventing URO accumulation in humans.
Commentaire de travail de M. Delvaux et al., pp. 16
Journal: Endoscopy (2008)

See also: Esophageal capsule endoscopy in patients with suspected esophageal disease: double blinded comparison with esophagogastroduodenoscopy and assessment of interobserver variabilityEndoscopy 2008; 40(01): 16-22DOI: 10.1055/s-2007-966935
Interferon-α2a and 13-&lt;I&gt;cis&lt;/I&gt;-retinoic acid with radiation treatment for high-grade glioma
Authors: Robert O. Dillman, W. Michael Shea, D. Fritz Tai, Khosrow Mahdavi, Neil M. Barth, Bharati R. Kharkar, Marshall M. Poor, Curtis K. Church, Carol Depriest
Journal: Neuro-Oncology (2001)
"Getting to know you and your child" screening questionnaire: Results from a Chicago-based collaborative.
Authors: Christine B. Weldon, Betty Roggenkamp, Erika D Owen, Jennifer Reichek, Zayda Stewart, Julia Rachel Trosman, Dipti Dighe, Asneha Iqbal, Eugene Suh, Rosa Berardi, Rani Ganesan, Daniel K. Choi, Tara O. Henderson
Journal: Journal of Clinical Oncology (2018)

150 Background: In 2013 the Institute of Medicine recommended that supportive oncology services be initiated at time of cancer diagnosis. Providers of pediatric cancer care in the Chicago metro area, supported by The Coleman Foundation, created and pilot tested a standard psycho-social stressors screening instrument for children with cancer and their families. Methods: The collaborative conducted structured review of tools: Psychosocial Assessment Tool (PAT), Social Work Assessment Tool (SWAT), National Comprehensive Cancer Network (NCCN) Problem List, and √IN; and collected input from social workers and oncology providers on stressors throughout the care continuum. The resulting tool was piloted in English and Spanish at 7 pediatric cancer hospitals. Providers qualitatively reported assessment of its usefulness. Results: Patients/family (n = 57) completed the “getting to know you and your child” instrument which inquired about caregivers, siblings, child’s likes/hobbies, school situation, SSI/SNAP, challenges, and cultural/religious preferences. Providers reported that almost all families found the tool useful “to think about support needs”; one said it was invasive. The tool assessed 12 psychosocial stressors; the mean per patient/family was 2.49 (range 0-11). The most frequent stressors were support from friends, family, community (30%), paying for food (26%), job flexibility (26%), school concerns (25%), emotional support for family (25%), and medical costs (23%). All who reported temporary housing also reported difficulty paying for a place to live (p &lt; 0.0001). Providers reported that the standard tool generated new insight into family structures, challenges and needs informing resolution efforts. Provider recommended adjustments: simplify terms for siblings, hobbies and spiritual, adding question about pets in the home. Conclusions: Pilot testing of a psycho-social screening tool for pediatric and adolescent oncology informed providers of patient/family needs in a standard manner. Four of the seven sites involved in the pilot are now implementing this tool as a standard practice; the remaining sites are performing analyses on how to incorporate the tool into their care processes.
A Manual of Allergy for General Practitioners
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cutaneous Medicine
Authors: John G. Downing
Journal: New England Journal of Medicine (1947)

THE skin pictures the general health of the patient much better than any other organ. Age is reflected in the pink bloom of infancy, the oiliness and pasty appearance of adolescence, the disfiguring yellowish spots and telangiectasia of middle age and the wrinkled, thin, overstretched and dry appearance of old age. Physicians of previous generations trained their powers of observation and palpation and carefully studied changes in the skin and mucous membranes; many diagnoses of systemic diseases resulted from their keen perception. Today, physicians fail to make use of these facilities and depend too much on mechanical devices and laboratory . . .
MENTAL CAPACITY SUFFICIENT TO SUSTAIN MARRIAGE IN LAW.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Asbestos in Water Supplies of the United States
Authors: James R. Millette, Patrick J. Clark, Judy Stober, Montiel Rosenthal
Journal: Environmental Health Perspectives (1983)

The review of available data on the concentrations of asbestos in U.S. water supplies suggests that the majority of water consumers are not exposed to asbestos concentrations over 1 million fibers/Liter. A few populations, however, may be exposed to concentrations over 1 billion fibers/L. Of the 538 water supplies for which waterborne asbestos data are available, 8% have concentrations of fibers over 10 million fibers/L. The vast majority of asbestos fibers found in U.S. water supplies are under 5 micron in length.
Re: Helena Vila-Reyes, G. Joel DeCastro, and James M. McKiernan’s Letter to the Editor re: Yunjin Bai, Yubo Yang, and Yin Tang’s Letter to the Editor re: Andrea Necchi, Marco Bandini, Giuseppina Calareso, et al. Multiparametric Magnetic Resonance Imaging as a Noninvasive Assessment of Tumor Response to Neoadjuvant Pembrolizumab in Muscle-invasive Bladder Cancer: Preliminary Findings from the PURE-01 Study. Eur Urol 2020; 77:636–43. Eur Urol 2020;77:e158: Can mpMRI Replace Conventional …
Authors: Valeria Panebianco, Francesco Del Giudice, Yoshifumi Narumi, Giuseppe Simone, Ettore De Berardinis, Jamed W.F. Catto
Journal: European Urology (2020)
THE USE OF NOVEL MODIFIED ENDOSCOPIC VACUUM THERAPIES IN THE MANAGEMENT OF A TRANSMURAL RECTAL WALL DEFECT
Authors: DTH de Moura, ES do Monte Junior, KE Hathorn, AM da Ponte-Neto, IB Ribeiro, FS de Medeiros, M Coronel, CC Thompson, EGH de Moura
Journal: Endoscopy (2020)

Endoscopic vacuum therapy(EVT) has become a safe and effective tool for intraluminal treatment of transmural gastrointestinal defects. A 29-year-old woman with familial adenomatous polyposis, status-post proctocolectomy two years prior, presented with daily fevers and rectal pain. CT scan demonstrated a leak at the ileorectal anastomosis. An end-ileostomy was performed, but there was ongoing concern for persistent leak. EVT was considered. The patient was successfully treated with a modified EVT system and was discharged from the hospital 28-days after the initial procedure. These novel cost-effective modified EVTs are feasible and appear to be as safe and effective as the traditional EVT.
Neonatal screening programme for phenylketonuria.
Journal: BMJ (1991)

conditions, f-ronti mild to severe.(iven that most patients have the tests offered to them, the decision about which tests shouldi be widely available becomes paramount.Which conditions arc considered to bc scrious enloLugh to warrant prenatal screeninig and suobsequent ter-mination?'\Xho should decide?As a first step towards a solution the views of scientists, clinicians, managers, and patients as swell as special interest groups, SLuch as those wNith disabilities, need to be determined.TFhe next task is to determine how these potentially conflicting views can be reflected in policy.Once a test is available how, when, and by whom should it be offered to increase the likelihood that the decision to undergo screening reflects more a woman's values and less the social influences inherent in medical consultations?Research on these issues is needed alongside the development of these tests to ensure that we do not become slaves to our own technological wizardry.
A specific antibody response to HCV E2 elicited in mice by intramuscular inoculation of plasmid DNA containing coding sequences for E2
Authors: V Tedeschi
Journal: Hepatology (1997)

As the chimpanzee, the only reliable animal model for hepatitis C virus (HCV) infection, is impractical for early stage testing of HCV vaccine candidates, we have evaluated the immune response in mice to an experimental plasmid based HCV vaccine. We used this system because DNA vaccines can be rapidly constructed without the necessity of large scale protein production and purification. In this preliminary study we tested the immune response in mice to HCV envelope glycoprotein, E2, induced by a eukaryotic expression plasmid. Protein expression was monitored by immunofluorescence in transfected tissue culture cells. Each mouse was inoculated intramuscular with 100 microg plasmid DNA and some mice were boosted after 5 weeks. Among 12 BALB/C mice inoculated, 10 developed antibody to E2 by the second week. The antibody levels increased steadily before reaching a plateau in mice receiving the booster, but in the nonboosted mice the antibody declined over time. The serum from one mouse was tested against a series of overlapping peptides covering most of E2. This serum contained antibodies recognizing two distinct epitopes beginning at amino acid 57 and amino acid 113 but no antibody was directed against peptides representing the hypervariable region of E2, antibody to which is thought to be important in HCV neutralization. We have shown that the use of plasmid based vaccines can induce a specific immune response in mice against HCV antigens. This system should be useful as the first step in vaccine development.
THE NAME OF THE GAME IS SAFETY
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Brain Tumors Simulating Other Psychiatric Disease
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Vanishing pancreatic calcifications. A nonspecific finding in chronic pancreatitis
Authors: M. Donowitz
Journal: JAMA (1974)

PANCREATIC calcifications, an accepted marker of chronic pancreatic inflammation, are most often associated with high intake of ethanol in this country and with protein malnutrition in India and the African countries. A decrease in the size of these calcifications or their disappearance has rarely been described.<sup>1</sup>In the case described, change in pancreatic calcifications was related to the development of a pancreatic pseudocyst, and not to neoplasm as is sometimes thought. <h3>Report of a Case</h3> A 48-year-old, black alcoholic man first developed acute pancreatitis in May 1961. On admission, amylase level was 572 Somogyi units/100 ml (normal, less than 200), and lipase level was 6.8 Cherry-Crandall units/ml (normal, less than 1.5); levels of calcium, phosphorus, and fasting blood glucose were normal. A flat plate roentgenogram of the abdomen showed multiple calcific densities adjacent to the L1-2 intervertebral space, a finding consistent with chronic pancreatitis. An oral cholecystogram was normal.