tbuckley/cabot-search huggingface dataset:
Consensus Programs, Vaccines, DNA Research
Journal: JAMA (1979)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Recruitment of Co-Metabolic Enzymes for Environmental Detoxification of Organohalides
Authors: Lawrence P. Wackett
Journal: Environmental Health Perspectives (1995)

Polyhalogenated compounds are often environmentally persistent and toxic to mammals.Microorganisms that metabolize these compounds can detoxify contaminated environments.Different biochemical mechanisms are used to metabolize polyhalogenated compounds, but few naturally occurring bacteria have this capability.A recombinant bacterium was constructed to metabolize polyhalogenated compounds to nonhalogenated end products.Seven genes were expressed in Pseudomonas putida G786 to biosynthesize cytochrome P450CAM and toluene dioxygenase.Cytochrome P450CAM catalyzed reductive dechlorinated reactions and toluene dioxygenase catalyzed oxidative dechlorination.With pen- tachloroethane, reductive dechlorination yielded trichloroethylene, which was further oxidized to formate and glyoxylate.The sequential action of cytochrome P450CAM and toluene dioxygenase with polyhalogenated compounds constitutes a novel engineered metabolic pathway.-
Why doctors must grapple with health economics
Authors: D Srivastava
Journal: BMJ (1987)

suggest that they are at high risk of developing leptospirosis, the remarkably low incidence of the disease in such communes argues to the contrary.The clustering of so many cases in the commune, the finding of only a moderate rise in the tempera- ture at the centre of a meatball cooked on a hot plate,2 and the very peculiar interaction of the index case with the commune strongly suggested that food was the common source.
Abstract 362: Depolymerized fucosylated chondroitin sulfate in pancreatic cancer, metastasis and cancer-associated thrombosis
Authors: Yiming Yao, Kavitha Godugu, Yongsheng Jin, Yi Jiang, SHAKER A. MOUSA
Journal: Cancer Research (2019)

Abstract The Depolymerized fucosylated chondroitin sulfate (dHG) prepared from natural fucosylated chondroitin sulfate, which was isolated from sea cucumber, showed remarkable anti-cancer efficacy in suppressing primary tumor growth, tumor angiogensis and metastasis. The anti-metastasis properties were demonstrated in multiple mouse cancer models, including B16F10 melanoma-induced lung metastasis model, 4T1 breast cancer induced lung metastasis model, Luciferase transfected SUIT-2 pancreatic cancer induced lung metastasis model as well as surgical removal SUIT-2 pancreatic tumor induced metastasis. Additionally, dHG demonstrated potent anti-angiogenesis efficacy against various growth factors-mediated angiogenesis. Cancer metastasis is a multiple process and regulated by a complex signaling network. Our In vitro studies demonstrated that dHG is a multiple targets agent. dHG inhibits angiogenesis and P-selectin, both are involved in cancer metastasis. dHG also induces TFPI release, especially TFPI-2 release. TFPI-2 has been recognized as a potent tumor suppressor. It inhibits the migration and invasion of human cancer cells. Low expression of TFPI-2 results in enhanced growth and metastasis of a variety of human tumors. Thrombelastography (TEG) showed that mixing of dHG and 1-10 picogram of TFPI-1 or TFPI-2 generated significant anti-thrombotic effect while dHG itself has very low anticoagulant activity. Thrombosis is a significant problem for cancer patient. dHG potentially inhibits thrombosis and normalizes hemostasis. Our studies demonstrated that dHG is a promising therapeutic agent for metastatic cancer and cancer-associated thrombosis management. Citation Format: Yiming Yao, Kavitha Godugu, Yongsheng Jin, Yi Jiang, SHAKER A. MOUSA. Depolymerized fucosylated chondroitin sulfate in pancreatic cancer, metastasis and cancer-associated thrombosis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 362.
INFECTION OF THE URINARY BLADDER FROM THE INTESTINE.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Th1/Th2 response profiles to the major allergens Cry j 1 and Cry j 2 of Japanese cedar pollen
Authors: K. Sugimura, S. Hashiguchi, Y. Takahashi, K. Hino, Y. Taniguchi, M. Kurimoto, K. Fukuda, M. Ohyama, G. Yamada
Journal: Allergy (1996)
High HDL2 levels lower postprandial lipids
Authors: P. Gunby
Journal: JAMA (1983)

A new study linking regular, vigorous physical activity with possible high density lipoprotein (HDL) cholesterol protection against heart disease won the Irvine H. Page Arteriosclerosis Research Prize for Young Investigators at the recent American Heart Association meeting in Dallas. Josef R. Patsch, MD, and colleagues at Baylor College of Medicine in Houston reported a positive relationship between augmented levels of HDL<sub>2</sub>, an HDL subfraction, and enhanced ability to break down and clear postprandial fat from the serum. The study involved 28 healthy volunteers, 23 men and five women. At the time the study began, three were essentially sedentary, 12 exercised moderately, and 13 exercised extensively. The volunteers, who ranged in age from 23 to 42 years, all had their HDL<sub>2</sub>levels measured. Then they were given "fatty milkshakes," 86% of the calories of which are derived from fat. All subjects had "milky" plasma after consuming the milkshake, but
Errors in Continuing Medical Education Questions and Answers
Journal: JAMA Psychiatry (2015)

ClinicalTrial and Component Analysis" published in the May issue of JAMA Psychiatry, 1 errors appeared in some questions and answers.For question 3, option D should have been 24%.For question 4, the question should have been, "Which treatment(s) resulted in the fewest number of nonsuicidal self-injuries?"And for question 5, the question should have been, "During the treatment year, depression symptoms improved most with:" and option E should have been omitted.This article was corrected online.1. Dialectical behavior therapy for high suicide risk in individuals with borderline personality disorder: a randomized clinical trial and component analysis.
An evaluation of the internship experience in New Jersey hospitals (1966-1967). A venture in voluntary regional cooperation
Authors: E. O. Hirsch
Journal: JAMA (1969)

During 1966 and 1967, 29 of the 39 hospitals conducting internships approved by the American Medical Association in New Jersey and representing more than 80% of the interns in the state joined in an internship evaluation by means of a preinternship and postinternship National Board Part III Examination. Through the cooperation of the hospitals' directors of medical education, there was almost 100% enrollment in the program by interns in participating hospitals. Improvement between the preinternship and postinternship examination was roughly the same for foreign as for American graduates, although foreign graduates obtained lower scores. Performance by American graduates was similar to performance of American graduates in other large groups. There was a large conversion from fail to pass among foreign graduates.
Federal ruling reins in liberal HIV testing law, consensus still lacking on controversial issue
Authors: R. Voelker
Journal: JAMA (1993)

DESPITE ATTEMPTS in recent years to destigmatize AIDS by treating the illness like any other infectious disease, an Alabama court says it still isn't so. In an October ruling, a federal judge in Montgomery, Ala, declared unconstitutional the portion of a state law that allowed HIV testing without written, informed consent if, based on a physician's "reasonable medical judgment," the patient is at high risk for infection. Overall, the 2-year-old law requires HIV testing with written, informed consent. But it listed three exceptions. Still intact are provisions that state explicit consent is unnecessary for the protection of health care workers, or if knowledge of the patient's HIV status will change the course of medical care. By upholding the two exceptions, advocates who believe that there is no substitute for explicit consent say the ruling doesn't go far enough. However, the decision appears to halt the pendulum pushed by some groups,
Virus-like Particles: Do They Correlate with Disease Stage?
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Technique for Detecting Intrauterine Cancer Suggested for Routine Office Use
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RENAL FAILURE AND BUNAMIODYL SODIUM
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Des Kindes Ernährung, Ernährungsstörungen und Ernährungstherapie.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tumour imaging
Authors: S. E. M. Clarke
Journal: Clinical Nuclear Medicine (1991)

The adequate management of any malignancy depends on several factors. The first is an accurate diagnosis. For the diagnosis to be accurate, not only must the site of the tumour be identified, but the exact tissue in which the tumour is arising must be determined. Although the histogenic type of the tumour may be readily apparent on light microscopy, more detailed investigations including histochemical techniques of resected tumour are often necessary to correctly characterize the malignancy in terms of tissue origin and degree of differentiation of the tumour. A further factor in contributing to decisions on management is the stage of the malignancy at the time of presentation or at the time of investigation.
Fourteenth Annual Report of the Board of Health of the State of Connecticut.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical student abuse. Incidence, severity, and significance
Authors: H. K. Silver
Journal: JAMA (1990)

In a survey of the incidence, severity, and significance of medical student abuse as perceived by the student population of one major medical school, 46.4% of all respondents stated that they had been abused at some time while enrolled in medical school, with 80.6% of seniors reporting being abused by the senior year. More than two thirds (69.1%) of those abused reported that at least one of the episodes they experienced was of "major importance and very upsetting." Half (49.6%) of the students indicated that the most serious episode of abuse affected them adversely for a month or more; 16.2% said that it would "always affect them." Students identified various types of abuse and proposed a number of measures for the prevention and management of abuse in medical school. We conclude that medical student abuse was perceived by these students to be a significant cause of stress and should be a major concern of those involved with medical student education. (<i>JAMA</i>. 1990;263:527-532)
Abstract P262: HIV/HCV Co-infection and the Risk of Cardiovascular Disease: A Systematic Review and Meta-analysis
Authors: Olatokunbo Osibogun, Oluseye Ogunmoroti, Erin D Michos, Babatunde Olubajo, Khurram Nasir, Purnima Madhivanan, Wasim Maziak
Journal: Circulation (2017)

Introduction: With improved antiretroviral therapy, the life expectancy of people living with human immunodeficiency virus (HIV) has increased. However, these individuals are now more susceptible to developing cardiovascular diseases (CVD). Prior studies examining the association between HIV and hepatitis C virus (HCV) co-infection and the risk of CVD, compared to HIV mono-infection, have differed in their conclusions. We conducted a systematic review and meta-analysis to clarify and quantify the association between HIV/HCV co-infection and CVD risk. We hypothesized that CVD risk will be synergistically increased by the persistent inflammatory responses of both viruses. Methods: We searched EMBASE, CINAHL, Google Scholar, PubMed, and Web of science from inception to October 2016 to identify studies on HIV/HCV co-infection and CVD, defined as coronary artery disease, congestive heart failure and stroke. The search was supplemented with a review of the reference list of articles. We used a random-effects model to abstract and pool data on the hazard ratios (HRs) for CVD. Hazard ratios were adjusted for traditional CVD risk factors. Results: Among the 280 articles reviewed, 4 cohort studies met the inclusion criteria with a total of 33,723 participants. Of these, 8,109 (24%) were HIV/HCV coinfected, 18,958 (56%) were HIV monoinfected while 6,656 (20%) comprised HCV monoinfected, HIV uninfected, and HIV/HBV coinfected participants. Pooled adjusted HRs for the association between HIV/HCV co-infection and CVD was 1.24 (95% CI 1.07-1.40) compared to HIV mono-infection. Test for homogeneity was not statistically significant [I 2 = 0.0%, P=0.397] (Figure). Conclusion: We found a consistent positive association showing that individuals with HIV/HCV coinfection had an increased CVD risk compared to those with HIV monoinfection. However, more research is needed to further examine this association, determine potential underlying mechanisms and evaluate whether treatment for HIV and HCV infections can reduce CVD outcomes.
Seventh Annual Report of the State Board of Health and Vital Statistics of the Commonwealth of Pennsylvania, 1891.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Court ruling on 'junk science' gives judges more say about what expert witness testimony to allow
Authors: C. Marwick
Journal: JAMA (1993)

THE BALL is back in the lower courts. That's where the Supreme Court has tossed it in a 7-2 decision that tells federal lower court judges that it's up to them to determine whether to allow expert witness testimony in cases that come before them. The case before the Supreme Court,<i>Daubert vs Merrell Dow</i>, was an appeal over a lawsuit alleging that birth defects occurring in two children were caused by Bendectin. The drug for treating nausea of pregnancy had been taken by each child's mother. Lower courts had ruled in favor of the manufacturer of Bendectin, Marion Merrell Dow Inc, Kansas City, Mo. It was one of more than 1000 cases brought by children with birth defects, whose mothers had taken Bendectin during their pregnancy (<i>JAMA</i>. 1993;269:2057). Merrell Dow had argued that in 30 published studies there was no statistically significant association between the use of Bendectin and