AB0963 Frequency of sexual dysfunction in psoriatic arthritis, Santo Domingo, Dominican Republic
Authors: J. Santana Peralta, A. Cornelio, D. Garcia, R. A. Alvarez Santana, T. Polanco Mora, L. Concepción Sanchez, I. Paulino, I. Mercedes, E. Rodriguez Bautista, T. Valdez Lorie, A. Feriz, R. Muñoz Louis
Journal: Annals of the Rheumatic Diseases (2022)

Background Psoriatic arthritis (PsA) is an inflammatory joint disease that cause structural damage, disability, and an impairment of quality of life. 1 Sexual function is a neglected area of quality of life in patients with PsA, with a high prevalence of dissatisfaction. 2 It has been described that there is no relationship between the activity of the disease and the degree of joint dysfunction. 3 In 1 out of 5 patients consider that the disease negatively impacts their sexuality. 4 CSFQ-14 (Changes in Sexual Functioning Questionnaire), evaluates changes in sexual functioning due to an illness or treatment in 5 domains with a score range 14-70; cut-off point indicating sexual dysfunction -41 men and -47 women. 5 Objectives To evaluate the frequency and degree of sexual dysfunction in patients with psoriatic arthritis. Methods Prospective, observational, cross-sectional study. The patients of the outpatient clinic of the rheumatology service of the Padre Billini teaching hospital were interviewed during November 2021. Inclusion criteria: ≥18 years, PsA diagnosis according to CASPAR classification criteria 2006. Exclusion criteria: diagnosis of another autoimmune disease, depression, treatment with antidepressants. We analyzed the data in SPSS23 and used the Pearson correlation coefficient with a statistical significance p=&lt;0.05 (rp) to relate the data. Results 58 met inclusion criteria. 63.8% (37) female, male 36.2% (21), mean age 54.8 + 11.75 y, mean diagnosis 7.9 y, married 55.2% (32), unmarried 39.7% (23), widowed 5.2% (3). Frequency of sexual dysfunction 39.7% (23), CSFQ-14 indicative of dysfunction in women 35.1% (23), men 47.6% (10). Female Domains: Pleasure dysfunction 35.1% (13), desire/interest 32.4% (12), desire/frequency 32.4% (12), arousal 24.3% (9), orgasm/completion 43.2% (16). Male Domains: Pleasure dysfunction 38.1% (8), desire/interest 47.6% (10), desire/frequency 33.3% (7), arousal 23.8% (5), orgasm/completion 42.9% (9). Correlation CSFQ-14/DAPSA28 domains: Pleasure dysfunction: DAPSA remission 19.2% (5), low 32.1% (9), moderate 50% (2). Desire/interest: DAPSA remission 34.6% (9), low 32.1% (9), moderate 100% (4). Desire/frequency: DAPSA remission 30.8% (8), low 37.5% (10), moderate 25% (1). Excitation: DAPSA remission 30.8% (8), low 17.9% (5), moderate 25% (1). Orgasm/completion: DAPSA remission 50% (13), low 37.5% (10), moderate 50% (2). r p =. 042 p&lt;0.05. Conclusion The study showed a modest frequency of global sexual dysfunction. In men it was superior. The orgasm/completion domain proved to be the most dysfunctional in both sexes. A statistically significant linear association of sexual dysfunction and disease activity was evident. References [1]Reygaerts T. Effect of Biologics on Fatigue in Psoriatic Arthritis: A Systematic Literature Review with Metaanalysis, Joint Bone Spine (2018). [2]Esteve E et al. Preliminary development of a questionnaire assessing the impact of psoriasis and psoriatic arthritis on patient’s perception of sexuality. Medicine (Baltimore). 2018 [3]Aguiar R, Ambrósio C. Sexuality in spondyloarthritis-the impact of the disease. Acta Reumatol Port. 2014 Apr-Jun;39(2):152-7. PMID: 25254264. [4]G Haugeberg, (2020): Perceived influence of health status on sexual activity in patients with psoriatic arthritis, Scandinavian Journal of Rheumatology. [5]Clayton AH, McGarvey EL. The Changes in Sexual Functioning Questionnaire (CSFQ): development, reliability, and validity. Psychopharmacol Bull. 1997;33(4):731-45. Disclosure of Interests None declared