tbuckley/cabot-search huggingface dataset:
Tolinapant, a Non-Peptidomimetic Antagonist of Inhibitors of Apoptosis Proteins, cIAP1/2 and XIAP, in Combination with the Hypomethylating Agents, Azacytidine and Decitabine Are Highly Synergistic in <i>in Vitro</i> Models of T Cell Lymphoma
Authors: John Sanil Manavalan, Ipsita Pal, Aidan Pursley, George A. Ward, Tomoko Smyth, Martin Sims, Jason A. Taylor, David J Feith, Thomas P. Loughran, Owen A. O'Connor, Enrica Marchi
Journal: Blood (2022)
Activity of <i>Ex Vivo</i> Graft and DLI Engineering within the Last Decade Increases, a Survey from the EBMT Cellular Therapy &amp; Immunobiology Working Party
Authors: Moniek de Witte, Jorinde Hoogenboom, Jarl Mooyaart, Christian Chabannon, Florent Malard, Annalisa Ruggeri, Jurgen Kuball
Journal: Blood (2022)
Histone Acetyltransferases Are Critical Interacting Proteins in NUP98-Rearranged Acute Myeloid Leukemia
Authors: Nicole L. Michmerhuizen, Masayuki Umeda, Ilaria Iacobucci, Bright Arthur, Danika Di Giacomo, Ryan Hiltenbrand, Pablo Portola, Sherif Abdelhamed, Hongling Huang, Peipei Zhou, Lingyun Long, Hao Shi, Yu Sun, Evangelia K. Papachristou, Chandra Chilamakuri, Clive S. D'Santos, Hongbo Chi, Jeffery M. Klco, Charles G. Mullighan
Journal: Blood (2022)
Efficacy of Frontline Treatments for Newly Diagnosed Transplant-Ineligible Multiple Myeloma, a Network Meta-Analysis
Authors: Maggie Wong, Chen Wang, Cinnie Yentia Soekojo, Hung Chew Wong, Sanjay De Mel, Melissa Ooi, Miny Samuel, Yu Yang Soon, Wee Joo Chng
Journal: Blood (2022)
Tracking Immune Reconstitution in the Bone Marrow Following Allogeneic Hematopoietic Transplantation in Humans Reveals Early Dominance of Innate Lymphoid Populations
Authors: Susan DeWolf, Jason Kuttiyara, Paola Vinci, John Slingerland, Leeann T. Marcello, Paul A. Giardina, William Donohoe, Richard J. Lin, Esperanza B. Papadopoulos, Boglarka Gyurkocza, Brian C. Shaffer, Martin S. Tallman, Sergio A. Giralt, Ioannis Politikos, Juliet N. Barker, Roni Tamari, Christina Cho, Miguel-Angel Perales, Marcel R.M. van den Brink, Alan M. Hanash
Journal: Blood (2022)
In Patients with Relapsed/Refractory AML Sequential Conditioning and Immediate Allogeneic Stem Cell Transplantation (allo-HCT) Results in Similar Overall and Leukemia-Free Survival Compared to Intensive Remission Induction Chemotherapy Followed By Allo-HCT: Results from the Randomized Phase III ASAP Trial
Authors: Matthias Stelljes, Jan Moritz Middeke, Gesine Bug, Eva-Maria Wagner, Lutz Peter Mueller, Schmid Christoph, Stefan W. Krause, Wolfgang Bethge, Edgar Jost, Uwe Platzbecker, Stefan Klein, Jörg Schubert, Judith Niederland, Martin Kaufmann, Kerstin Schäfer-Eckart, Markus Schaich, Henning Baldauf, Friedrich Stölzel, Cathleen Petzold, Christoph Röllig, Nael Alakel, Björn Steffen, Beate Hauptrock, Christian Reicherts, Christoph Schliemann, Hubert Serve, Alexander H. Schmidt, Martin Bornhäuser, Jan-Henrik Mikesch, Johannes Schetelig
Journal: Blood (2022)
Identification of <i>PTPN11</i> mutations As Early Events in the Development of Acute Myeloid Leukemia
Authors: Sydney Fobare, Shelley Orwick, Jessica Kohlschmidt, Tom Sesterhenn, Krzysztof Mrózek, Ben Wronowski, Megan Johnstone, Andrew J. Carroll, Richard M. Stone, Eunice S. Wang, Jonathan E. Kolitz, Bayard L. Powell, John P Perentesis, Ann-Kathrin Eisfeld, Erin Hertlein, John C. Byrd
Journal: Blood (2022)
A Phase II Randomized Multi-Center Study to Evaluate the Safety and Efficacy of Infusion of Memory T Cells As Adoptive Therapy in Coronavirus Pneumonia and/or Lymphopenia (RELEASE NCT04578210)
Authors: Antonio Perez, Cristina Ferreras, Clara Hernandez, Alejandro Martín-Quirós, Karima Al-Akioui, Marta Mora-Rillo, Fátima Ibáñez, Rosa Goterris, Raquel De Paz Arias, Pilar Guerra-García, Javier Queiruga-Parada, Pablo Molina, Merche Bou, Carmen Mestre-Durán, Alberto Borobia, Antonio J. Carcas, María Luisa Briones, Jose Luis Vicario, Miguel Ángel Moreno, Antonio Balas, Cristina Eguizábal, Bernat Soria, Carlos Solano
Journal: Blood (2022)
Non-Restrictive Diet Does Not Increase Infections in Patients with Neutropenia after Stem Cell Transplantation: Final Analysis of the Neutrodiet Multicenter, Randomized Trial
Authors: Federico Stella, Vincenzo Marasco, Giorgia Virginia Levati, Cecilia Vismara, Anna Guidetti, Annalisa Chiappella, Giulia Perrone, Cristina Tecchio, Nicola Mordini, Martina Pennisi, Giorgia Ferrara, Giorgia Gobbi, Lucia Saracino, Cristiana Carniti, Paolo Corradini
Journal: Blood (2022)
Individualized Dosing of Anti-Thymocyte Globulin Led to Reduced CMV/EBV Reactivation and Superior Overall Survival in Adult Unmanipulated Haploidentical Peripheral Blood Stem Cell Transplantation: A Prospective Phase II Study
Authors: Haitao Wang, Liping Dou, Lili Wang, Bo Peng, Nan Wang, Yingxin Zhao, Jishan Du, Daihong Liu
Journal: Blood (2022)
Natural History of Pediatric Patients with Sickle Cell Disease and Concurrent Cerebral Vasculopathies: Report of 62 Cases from a Single Institution
Authors: Joanna E. Papadakis, Paulina Piwowarczyk, Daniel S. Weber, Anna L. Slingerland, Dylan S. Keusch, Matthew M. Heeney, Edward R. Smith, Alfred P. See, Natasha M. Archer
Journal: Blood (2022)
Elevated Levels of Low Density Lipoprotein (LDL) Trigger VWF Self-Association into Fibers and Bundles and Potentiate Microvascular Thrombosis
Authors: Dominic W. Chung, Kimsey Platten, Koya Ozawa, Raymond Adili, Nathalie Pamir, Forrest D Nussdorfer, Alexander E St. John, Minhua Ling, Jennie Le, Jeff Harris, Junmei Chen, Sergio Fazio, Jonathan Lindner, José A. López
Journal: Blood (2022)
GB5121, a Brain-Penetrant, Irreversible BTK Inhibitor, Demonstrates Potent Anti-Tumor Activity in a Novel Mouse Model of Intracranial Lymphoma
Authors: Isharat Yusuf, Marcos W Steinberg, Maricel Gozo, Bryan Clemons, Kay Hou, David Guimond, Mark J Rose, Kristen Taylor Meadows, Laura Carter
Journal: Blood (2022)
Evaluation of Bleeding and Thrombocytopenia in Older Adults with Acute Myeloid Leukemia Treated with Hypomethylating Agents: A Systematic Review and Meta-Analysis
Authors: Neelan Sriranjan, Anna R. Blankstein, Nora Choi, Kristjan Paulson, David Sanford, Lee Mozessohn, Donald S. Houston, Emily Rimmer, Sylvain Lother, Asher Mendelson, Allan Garland, Rena Buckstein, Annette E. Hay, Ryan Zarychanski, Brett L. Houston
Journal: Blood (2022)
Improvements in Lymphoma Symptoms and Health-Related Quality of Life in Patients with Relapsed or Refractory Large B-Cell Lymphoma Treated with Subcutaneous Epcoritamab (EPCORE NHL-1)
Authors: Tycel Phillips, Pieternella Lugtenburg, Anupama Kalsekar, Alex Mutebi, Anthony Wang, Julie Blaedel, Katherine Kosa, Susan Martin, Mariana Sacchi, Catherine Thieblemont
Journal: Blood (2022)
Bortezomib in Relapsed/Refractory Autoimmune-Mediated Thrombotic Thrombocytopenic Purpura: A Single-Center Case Series and Systematic Review
Authors: Nicholas C.J. Lee, Sean Yates, Siayareh Rambally, Ravindra Sarode, Ibrahim F. Ibrahim, Yu-Min Shen, Sandra L. Hofmann, Natalie Bavli
Journal: Blood (2022)
Once Weekly Selinexor, Carfilzomib and Dexamethasone (XKd) in Triple Class Refractory Multiple Myeloma
Authors: Gary J. Schiller, Sascha A. Tuchman, Natalie Callander, Muhamed Baljevic, Adrianna C Rossi, Rami Kotb, Darrell J White, Nizar J. Bahlis, Heather J. Sutherland, Sumit Madan, Richard Leblanc, Christopher P. Venner, William I. Bensinger, Dane R. Van Domelen, Chris Zhang, Ohad S. Bentur, Brea Lipe
Journal: Blood (2022)
A Simple Risk-Scoring Model for Estimating the Prognostic Impact of 1q Gain in Patients with Newly-Diagnosed Multiple Myeloma
Authors: Fengyan Jin, Peiyu Yang, Haimin Chen, Xinyue Liang, Weiling Xu, Shanshan Yu, Wenyang Huang, Xingchen Yi, Qiang Guo, Mengru Tian, Tingting Yue, Mengyao Li, Yingjie Zhang, Mengxue Zhang, Yurong Yan, Zhongli Hu, Shaji K Kumar, Fan Zhou, Yun Dai
Journal: Blood (2022)
Next Generation Sequencing Identifies Light-Chain Amyloid (AL)-Related <i>Igvl</i> Genes in Patients with λ Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM)
Authors: Ping Zhou, Mahesh M Mansukhani, Denis Toskic, Stephanie Scalia, Lisa Lee, Sandy W. Wong, Sascha A. Tuchman, James E. Hoffman, Teresa Fogaren, Cindy Varga, Suzanne Lentzsch, Raymond Comenzo
Journal: Blood (2022)
Impact of Donor and Patient CMV Serology in Children Receiving First Geno-Identical or Unrelated HSCT for Malignant Hematological Disease: An EBMT Retrospective Registry Study
Authors: Elif Ince, Jacques-Emmanuel Galimard, Marianne Ifversen, Arnaud Dalissier, Zofia Szmit, Franco Locatelli, Oana Mirci-Danicar, Petr Sedlacek, Jean-Hugues Dalle, Mouhab Ayas, Rose-Marie Hamladji, Andrea Biondi, Jan Styczynski, Yves Bertrand, Elena Skorobogatova, Abdelghani Tbakhi, Katrine Kielsen, Vassiliki Kitra-Roussou, Franca Fagioli, Wolfgang Holter, Andreas H. Groll, Mahmoud Aljurf, Mervi Taskinen, Marc Bierings, Roland Meisel, Simone Cesaro, Krzysztof Kalwak, Selim Corbacioglu
Journal: Blood (2022)
Pharmacological Management of GI Bleed Secondary to Arteriovenous Malformations: A Systematic Review
Authors: Mamoon Ahmed, Junaid Khan, Muhammad Fareed Khalid, Ali Hassan Mushtaq, Ayesha Abbas, Suneeba Javed Chattha, Hira G. Shaikh, Mohammad Ammad-ud-din, Muhammad Umair Mushtaq, Moazzam Shahzad
Journal: Blood (2022)
Rusfertide for Polycythemia Vera: Similar Dosing in Patients Receiving Therapeutic Phlebotomy Alone or in Combination with Cytoreductive Treatment
Authors: Aaron T. Gerds, Jason Gotlib, Jeanne M. Palmer, Naveen Pemmaraju, Prithviraj Bose, Yelena Ginzburg, Frank Valone, Nishit B. Modi, Sarita Khanna, Paula G. O'Connor, Suneel K. Gupta, Ronald Hoffman
Journal: Blood (2022)
A Phase 2, Randomized Trial Evaluating the Safety and Efficacy of Pozelimab and Cemdisiran in Patients with Paroxysmal Nocturnal Hemoglobinuria
Authors: Jun Ho Jang, Raymond Wong, Rodrigo Pavani, Lisa Aurand, Bradley Dain, Lorah Perlee, Amal Souttou, Jonathan Weyne, Richard Kelly
Journal: Blood (2022)
<i>Cohesin-STAG2 Mutations Alter Chromatin Structure and Gene Regulation in Human Acute Myeloid Leukemia</i>
Authors: Alexander Fischer, Roger Mulet-Lazaro, Margit Nützel, Stanley van Herk, Hanna Stanewsky, Ute Ackermann, Edith Reuschel, Nicholas Strieder, Inmaculada Hernandez-Lopez, Wolfgang Herr, Peter J.M. Valk, Michael Rehli, Ruud Delwel, Claudia Gebhard
Journal: Blood (2022)
Expression of CD38 and Zap-70 Antigens in Chronic Lymphocytic Leukemia
Authors: Flavio Cristine Medeiros Theodoro, Giovani Arlindo Silva, Taissa Moura Oliveira, Rafael Duarte Lima, Maria das Graças Pereira Araújo, Lenilton Silva Silveira, Victor lima Soares, Ciro Alexandre Mercês Gonçalves, Arthur Felipe Araujo Dantas, Gustavo Henrique de Medeiros Oliveira, Dany Geraldo Kramer Cavalcanti Silva, Hugo Diogenes De Oliveira Paiva, Catarina Silva de Souza Diogenes, Aline Abreu Diogenes, Maria Jacqueline Nogueira Souza, Aldair Sousa Paiva, Geraldo Barroso Cavalcanti
Journal: Blood (2022)
Pre-Clinical Characterization of VGA039, an Anti-Protein S Monoclonal Antibody Being Developed As a Universal Hemostatic Agent for Various Bleeding Disorders
Authors: Lilley Leong, Tony Byun, Benjamin Kim, Ian Huck, Abel Silva, Joanne Chan, Young Cho, John Liu, Christopher J. Horvath, Stephen J. Moore, Sandip Panicker
Journal: Blood (2022)
PRMT5 Inhibition Alters Mitochondrial Dynamics in Mantle Cell Lymphoma Creating Vulnerability to BH3 Mimetic Compounds
Authors: Claire Hinterschied, Fiona Brown, Janani Ravikrishnan, JoBeth Helmig-Mason, Kaylee R. Harrison, Aneeq Yasin, Shelby Sloan, Mackenzie Long, Neha Bhagwat, Kris Vaddi, Peggy Scherle, Jennifer A. Woyach, Selina Chen-Kiang, Olivier Elemento, Jihye Paik, Robert A. Baiocchi
Journal: Blood (2022)
Ibrutinib and Venetoclax in Previously Untreated Waldenström Macroglobulinemia
Authors: Jorge J. Castillo, Shayna Sarosiek, Andrew R. Branagan, David J. Sermer, Catherine A. Flynn, Carly Leventoff, Megan Little, Timothy P White, Kirsten Meid, Alexa Canning, Maria Luisa Guerrera, Amanda Kofides, Xia Liu, Manit Munshi, Nicholas Tsakmaklis, Christopher J Patterson, Zachary R Hunter, Steven P Treon
Journal: Blood (2022)
Magnetically Empowered Malignant Tumor Cells As Micro-Living Motors to Construct a Bone Original or Bone Metastasis Human-Mouse Chimera Tumor Model
Authors: Jialu Zhang, Zhengyuan Wang, Jiawei Xu, Luxia Tang, Dingyi Zhang, Qiyan Chen, Jinyan Luo, Xiangwei Kong, Yanni Hu, Leyi Tan, Xueqin Zhao, Qianli Jiang
Journal: Blood (2022)
Long-Term Efficacy Analysis of Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Acute Myeloid Leukemia Using Melphalan Instead of Cyclophosphamide As a Myeloablative Conditioning Regimen
Authors: Ying Zhang, Aiming Pang, Donglin Yang, Yong Huang, Jialin Wei, Yi He, Qiaoling Ma, Sizhou Feng, Mingzhe Han, Erlie Jiang
Journal: Blood (2022)
<i>TP53</i> Mutations Are Associated with Increased Infections and Reduced Hematopoietic Cell Transplantation Rates in Myelodysplastic Syndrome and Acute Myeloid Leukemia
Authors: Jennifer Marvin-Peek, Ashwin Kishtagari, Reena Jayani, Bhagirathbhai Dholaria, Tae Kon Kim, Emily F Mason, Brian G. Engelhardt, Heidi Chen, Adetola A. Kassim, Michael R. Savona, Bipin Savani, Michael Byrne
Journal: Blood (2022)
Preliminary Results of Voice (Virtual Opinions poll Independent Centered on CLL patients’ Experience): A Global Survey to Assess the Disease-Specific Knowledge and Perspectives of Real-World Patients with CLL
Authors: Constantine S. Tam, Javier Pinilla Ibarz, Volkan Karakus, Catherine Moura, Miguel Arturo Pavlovsky, Fernando Nicolás Piotrowsky, Martin Šimkovič, Andrew Smith, Stephan Stilgenbauer
Journal: Blood (2022)
<i>IDH2</i> mutations in Hematological Malignancies: Distribution, Hot Spots, Clonal Development and Identification of a Novel (cyto-)Genetically Defined Subgroup
Authors: Anna Stengel, Manja Meggendorfer, Wencke Walter, Constance Baer, Niroshan Nadarajah, Stephan Hutter, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach
Journal: Blood (2022)
Transcriptome Analysis and Machine Learning Prioritize Therapeutic Strategies for High-Risk Pediatric AML Patients of the KMT2A-Fusion Subgroup
Authors: Alyssa Obermayer, Sijie Yao, Jenny L. Smith, Rhonda E. Ries, Yi-Cheng Wang, Jason E Farrar, Scott N Furlan, Tim Triche, Xiaotu Ma, Benjamin J. Huang, Xuefeng Wang, Soheil Meshinchi, Timothy I. Shaw
Journal: Blood (2022)
Metagenomic Next-Generation Sequencing for Pathogens in Bronchoalveolar Lavage Fluid Improve the Survival of Patients with Pulmonary Complications after Allogeneic Hematopoietic Stem Cell Transplantation
Authors: Zaihong Shen, Jun Yang, Yu CAI, Liping Wan, Chongmei Huang, Xiaowei Xu, Jiahua Niu, Xinxin Xia, Chang Shen, Huiying Qiu, Kun Zhou, Yin Tong, Xianmin Song
Journal: Blood (2022)
Optimization of Intravenous Odronextamab Step-up Regimen for Reducing the Risk of High-Grade Cytokine Release Syndrome
Authors: Min Zhu, Jurriaan Brouwer-Visser, Srikanth R. Ambati, Hesham Mohamed, Vladimir Jankovic, Fang Wang, Hong Yan, Jingxian Cai, Carolina Leite De Oliveira, Melanie Ufkin, John D. Davis, Aafia Chaudhry, Masood Khaksar Toroghi
Journal: Blood (2022)
Do Unbalanced <i>MYC</i> Break-Apart FISH Patterns Indicate the Presence of a <i>MYC</i> Rearrangement?
Authors: Brett Collinge, Susana Ben-Neriah, Laura K Hilton, Waleed Alduaij, Tracy Tucker, Graham W Slack, Pedro Farinha, Jeffrey W. Craig, Merrill Boyle, Barbara Meissner, Kelly Mekwunye, Diego Villa, Alina S. Gerrie, Laurie H. Sehn, Kerry J. Savage, Ryan D. Morin, Andrew J. Mungall, Christian Steidl, David W. Scott
Journal: Blood (2022)
Optimal Sequencing Determination in Relapsed Multiple Myeloma
Authors: Salyka M. Sengsayadeth, Bridget Fitzgerald, Bharat Nandakumar, Bicky Thapa, Timothy Martin Schmidt, Rebecca Silbermann, Heidi Chen, Saurabh Chhabra, Natalie Callander, Shaji K Kumar, Luciano J. Costa
Journal: Blood (2022)
Time-Limited Ibrutinib and Tisagenlecleucel Is Highly Effective in the Treatment of Patients with Relapsed or Refractory Mantle Cell Lymphoma, Including Those with <i>TP53</i> Mutated and Btki-Refractory Disease: First Report of the Tarmac Study
Authors: Adrian Minson, Nada Hamad, Chan Y. Cheah, Constantine S. Tam, Piers Blombery, David A Westerman, Stephen Lade, David Ritchie, Rachel M Koldej, Mary Ann Anderson, Amit Khot, John F. Seymour, Molly Robertson, Imogen R Caldwell, Georgina L Ryland, Jing Xie, Huw Morgan, Michael Dickinson
Journal: Blood (2022)
Association of Body Mass Index With 21-Gene Recurrence Score Among Women With Estrogen Receptor–Positive, <i>ERBB2</i>–Negative Breast Cancer
Authors: Janghee Lee, Hakyoung Kim, Soong June Bae, Jung Hwan Ji, Jong Won Lee, Byung Ho Son, Sei Hyun Ahn, Joon Jeong, Sae Byul Lee, Sung Gwe Ahn
Journal: JAMA Network Open (2022)

Importance Body mass index (BMI) may affect the 21-gene recurrence score (RS) in patients with ER-positive, ERBB2 -negative breast cancer. If high BMI increases genomic risk in ER-positive, ERBB2 -negative breast cancer, weight control will become more important. Objective To assess the association between RS and BMI according to age groups and address BMI as a factor associated with high RS. Design, Setting, and Participants This cohort study included 2295 patients with ER-positive, ERBB2 -negative breast cancer who had undergone a multigene assay between March 29, 2010, and December 31, 2020, in 2 hospitals. All of the study patients were Korean women, and the median follow-up period was 45 months (range, 1-40 months). The correlations between continuous RS and BMI were investigated. A high BMI was defined as a body mass index greater than or equal to 25. In the younger age group (age ≤45 years), a high RS was defined as an RS of greater than 20. Exposures Body mass index. Main Outcomes and Measures The Pearson correlation coefficient was used to estimate the association between RS and BMI. A multivariable binary logistic model was used to identify high RS. Results Among the 2295 women included (mean [SD] age, 49.8 [4.00] years; range, 22-81 years), 776 were aged 45 years or younger; RS and BMI were weakly correlated (correlation coefficient, 0.119; P &amp;amp;lt; .001) in this younger group. Among them, the proportion of patients with an RS greater than 20 was significantly higher in the high BMI group than in the normal BMI group (45.5% [46 of 101] vs 27.3% [184 of 675]; P &amp;amp;lt; .001). In the multivariable analysis, high BMI was an associated factor for high RS (odds ratio, 2.06; 95% CI, 1.28-3.32; P = .003). The 21-gene multigene assay-guided chemotherapy rate was significantly higher in patients with high BMI (30.7% [31 of 101] vs 20.2% [136 of 674]; P = .02). Conclusions and Relevance In this cohort study of women aged 45 years or younger, high BMI was associated with higher RS in those with ER-positive, ERBB2 -negative breast cancer; further studies are necessary to examine the underlying mechanisms.
CD73 Inhibition Reverses Immunosuppression and Has Potential As an Immunomodulatory Therapy in Patients with Multiple Myeloma
Authors: Melissa R Junttila, Arghya Ray, Robert Warne, Xi R Chen, Ting Du, Fang Lui, Subhash Katewa, Brian Blank, Jared Moore, Chudi Ndubaku, Christophe Colas, Pratik S Multani, Omar Nadeem, Dharminder Chauhan, Kenneth C. Anderson, Lori Friedman
Journal: Blood (2022)
Blinatumomab in Combination with an Intensive Pediatric Protocol Results in High Rates of Day 79 MRD Negativity in Adolescent and Young Adult Acute Lymphoblastic Leukemia - Preliminary Results of the Australasian Leukaemia and Lymphoma Group (ALLG) ALL09 "Sublime” Study
Authors: Matthew Greenwood, Shane Gangatharan, Michael Philip Osborn, Ashley P Ng, Shaun Fleming, Pasquale Fedele, Toby Trahair, John Casey, Sally Mapp, Carol Cheung, Tasman Armytage, Michelle Henderson, Rosemary Sutton, Philip McCloud, Stephen R Larsen, Peter Presgrave, John Kwan, Samuel Bennett, Chun Yew Fong, Luciano Dalla Pozza
Journal: Blood (2022)
Impact of Ibrutinib in Quality of Life (QoL) in Patients with Chronic Lymphocytic Leukemia(CLL): Real World Experience in Argentina
Authors: María Jose Mela Osorio, Astrid Pavlovsky, Carolina Pavlovsky, Isolda I Fernandez, Manuela Clavijo, Augusto Miroli, Federico Sackmann, Guillermina Remaggi, Luciana C Ferrari, Mariana Juni, Carolina Sighel, Maximiliano Riddick, Miguel Arturo Pavlovsky
Journal: Blood (2022)
Multi-Antigen Targeting By Novel Combination of CAR-T Cells and hnCD16 Transgene, Yields in Complete Tumor Clearance Via Antibody Dependent Cellular Cytotoxicity
Authors: Soheila Shirinbak, Joy Grant, Wen-I Yeh, Angela Gentile, Bishwas Shrestha, Bi-Huei Yang, Mochtar Pribadi, Shohreh Sikaroodi, Amit Mehta, Amanda D Yzaguirre, Yijia Pan, Chia-Wei Chang, Tom Lee, Layton Smith, Jianming Wu, Bruce Walcheck, Martin Hosking, Bahram Valamehr
Journal: Blood (2022)
Low-Dose Radiation Improves Anti-CD19 CAR T-Cells Efficacy in Diffuse Large B-Cell Lymphoma through Fas/FasL Pathway
Authors: Mohammad Alhomoud, Jeremie Martinet, Mayumi Sugita, Takahiro Yamazaki, Olivier Boyer, Lorenzo Galluzzi, Silvia C Formenti, Koen Van Besien, Monica L. Guzman
Journal: Blood (2022)
Non-Canonical Gli1 Activation Mediates Profibrotic Hematopoiesis-Stroma Crosstalk in MPN
Authors: Jessica E. Pritchard, Juliette Pearce, Inge Snoeren, Stijn Fuchs, Katrin Götz, Silke Wagner, Kathrin Olschok, Nicolas Chatain, Steffen Koschmieder, Marie-Luise Berres, Ivan Costa, Helene Gleitz, Rafael Kramann, Rebekka K. Schneider
Journal: Blood (2022)
Phase 1 Study of CD19 Targeted CD28 Costimulatory Agonist in Combination with Glofitamab to Enhance T Cell Effector Function in Relapsed/Refractory B Cell Lymphoma
Authors: Michael Dickinson, Giuseppe Gritti, Carmelo Carlo-Stella, Harriet S Walter, David Carlile, Nicole Getzmann, Samira Curdt, Emma Harrop, Abiraj Keelara, Koorosh Korfi, Remi Labatut, Francesca Michielin, Sarah Louise Mycroft, Tom Moore, Robert Nutbrown, Giuseppe Palldino, Matt Whayman, Johannes Sam, Martin Weisser, Katharina E Lechner, Franck Morschhauser, Martin Hutchings
Journal: Blood (2022)
Long Follow-up of the Response-Adjusted Therapy for Advanced Hodgkin Lymphoma (RATHL) Trial (CRUK/07/033) Confirms the Safety of Both De-Escalation and Intensification of Chemotherapy
Authors: Stefano Luminari, Alexander Fosså, Judith Trotman, Daniel Molin, Francesco Annibale d'Amore, Gunilla Enblad, Leanne Berkahn, Sally F Barrington, John Radford, Massimo Federico, Amy A. Kirkwood, Peter Johnson
Journal: Blood (2022)
Anti CD19 CART Therapy Following Allogenic Hematopoietic Stem Cell Transplantation Improved the Survival of Patients with <i> <i>BCR::ABL1</i> </i>-like Acute Lymphoblastic Leukemia
Authors: Haiping Dai, Wei Cui, Hongjie Shen, Qian Wang, Jia Yin, Zheng Li, Depei Wu, Xiaowen Tang
Journal: Blood (2022)
Off-the-Shelf, Multiplexed-Engineered iPSC-Derived CD33 CAR-NK Cells for Treatment of Acute Myeloid Leukemia
Authors: Yiyun Wang, Linqin Wang, Mi Shao, Xiangjun He, Yanan Yue, Yixuan Zhou, Luhan Yang, He Huang, Yongxian Hu
Journal: Blood (2022)
Empagliflozin Modifies Neutrophils' Subsets in Patients with Glycogen Storage Disease Type Ib By Increasing Mature Neutrophils and Decreasing Immature Neutrophils
Authors: Fabiola Guerra, Serena Gasperini, Sonia Bonanomi, Viola Crescitelli, Liviana Da Dalt, Giuseppe D Norata, Marta Balzarini, Andrea Biondi, Andrea Baragetti, Francesco Saettini
Journal: Blood (2022)
<i>TRAF3</i> Loss-of-Function Reveals the Non-Canonical NF-Κb Pathway As a Therapeutic Target in Diffuse Large B-Cell Lymphoma
Authors: Michael Y. Li, Lauren C. Chong, Bruce W Woolcock, Adèle Telenius, Susana Ben-Neriah, Graham W Slack, Vivian Lam, Aixiang Jiang, Elena Viganò, Tomohiro Aoki, Shannon Healy, Gerald Krystal, Leandro Venturutti, David W. Scott, Christian Steidl
Journal: Blood (2022)
Epigenetic Dysregulation Leads to Enhanced IL-1β Signaling and Transcriptional Responses in <i>TET2</i> Deficient HSPCs
Authors: Matthew T. Jenkins, Timothy J Scott, Lindsey N Guerin, Alana M Franceski, Yunli E Chu, Pawan Bhat, Chad R. Potts, Robert S. Welner, Emily Hodges, Brent Ferrell
Journal: Blood (2022)