Contemporary Natural History of Coronary Artery Disease
Authors: Michael McDermott, David E. Newby
Journal: Annals of Internal Medicine (2023)

EditorialsApril 2023Contemporary Natural History of Coronary Artery DiseaseMichael McDermott, MBChB and David E. Newby, DM, PhDMichael McDermott, MBChBBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom and David E. Newby, DM, PhDBHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United KingdomAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M23-0533 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail The widespread introduction of coronary computed tomography (CT) angiography now allows for the accurate noninvasive detection of coronary artery disease. This has predominantly focused on patients with symptoms suggestive of coronary artery disease and is now the first-line test of choice for patients with stable chest pain in many parts of the world. This escalating use of coronary CT angiography has lowered the threshold for scanning persons who are considered at risk for coronary artery disease, even in the absence of symptoms. Although the clinical benefits of screening for disease have yet to be determined, identification of coronary artery disease ...References1. Fuchs A, Kühl JT, Sigvardsen PE, et al. Subclinical coronary atherosclerosis and risk for myocardial infarction in a Danish cohort. Ann Intern Med. 2023;176:489-95. doi:10.7326/M22-3027 LinkGoogle Scholar2. Bergström G, Persson M, Adiels M, et al. Prevalence of subclinical coronary artery atherosclerosis in the general population. Circulation. 2021;144:916-29. [PMID: 34543072] doi:10.1161/CIRCULATIONAHA.121.055340 CrossrefMedlineGoogle Scholar3. SCOT-HEART Investigators. CT coronary angiography in patients with suspected angina due to coronary heart disease (SCOT-HEART): an open-label, parallel-group, multicentre trial. Lancet. 2015;385:2383-91. [PMID: 25788230] doi:10.1016/S0140-6736(15)60291-4 CrossrefMedlineGoogle Scholar4. Nasir K, Cainzos-Achirica M, Valero-Elizondo J, et al. Coronary atherosclerosis in an asymptomatic U.S. population: Miami Heart Study at Baptist Health South Florida. JACC Cardiovasc Imaging. 2022;15:1604-18. [PMID: 36075621] doi:10.1016/j.jcmg.2022.03.010 CrossrefMedlineGoogle Scholar5. Singh T, Bing R, Dweck MR, et al. Exercise electrocardiography and computed tomography coronary angiography for patients with suspected stable angina pectoris: a post hoc analysis of the randomized SCOT-HEART trial. JAMA Cardiol. 2020;5:920-8. [PMID: 32492104] doi:10.1001/jamacardio.2020.1567 CrossrefMedlineGoogle Scholar6. Hoffmann U, Ferencik M, Udelson JE, et al; PROMISE Investigators. Prognostic value of noninvasive cardiovascular testing in patients with stable chest pain: insights from the PROMISE trial (Prospective Multicenter Imaging Study for Evaluation of Chest Pain). Circulation. 2017;135:2320-32. [PMID: 28389572] doi:10.1161/CIRCULATIONAHA.116.024360 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Michael McDermott, MBChB; David E. Newby, DM, PhDAffiliations: BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United KingdomNote: The authors are investigators of the SCOT-HEART 2 trial.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M23-0533.Corresponding Author: David E. Newby, DM, PhD, Centre for Cardiovascular Science, The University of Edinburgh, Chancellor's Building, Edinburgh EH16 4SU, United Kingdom; e-mail, d.e.[email protected].ac.uk.This article was published at Annals.org on 28 March 2023. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoSubclinical Coronary Atherosclerosis and Risk for Myocardial Infarction in a Danish Cohort Andreas Fuchs , Jørgen Tobias Kühl , Per Ejlstrup Sigvardsen , Shoaib Afzal , Andreas Dehlbæk Knudsen , Mathias Bech Møller , Martina Chantal de Knegt , Mathias Holm Sørgaard , Børge Grønne Nordestgaard , Lars Valeur Køber , and Klaus Fuglsang Kofoed Metrics April 2023Volume 176, Issue 4Page: 574-575KeywordsAngiographyAtherosclerosisCoronary arteriesCoronary heart diseaseMyocardial infarction ePublished: 28 March 2023 Issue Published: April 2023 Copyright & PermissionsCopyright © 2023 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...