tbuckley/cabot-search huggingface dataset:
Donor Hematopoietic Cell Telomere Length and Magnitude of Post-HCT Shortening Predict Survival in Early Stage Leukemia and Myelodysplastic Syndrome
Authors: Shahinaz M. Gadalla, Hormuzd Katki, Tsung-Po Lai, Casey Dagnall, Caitrin Bupp, Amy Hutchinson, James Anderson, Kyra Mendez, Stephen R. Spellman, Valerie Stewart, Sharon Savage, Stephanie J. Lee, John Levine, Wael Saber, Abraham Aviv
Journal: Blood (2023)
Validation of Differentially Expressed Micrornas in Primary Immune Thrombocytopenia Suggests Mir-199a-5p Is a Potential Diagnostic Biomarker
Authors: Lamya Garabet, Anbjørg Rangberg, Raul Teruel-Montoya, Maria Luisa Lozano, Christine Monceyron Jonassen, Waleed Ghanima
Journal: Blood (2023)
Results from an Intergroup Randomized Phase II Study of the Combinations of Ipilimumab, Nivolumab and Brentuximab Vedotin in Patients with Relapsed/Refractory Classic Hodgkin Lymphoma: A Trial of the ECOG-ACRIN Research Group (E4412)
Authors: Catherine S Diefenbach, Opeyemi Jegede, Stephen M Ansell, Christian Steidl, Yasodha Natkunam, David W. Scott, Neha Mehta-Shah, Jennifer E Amengual, Christopher J. Forlenza, Peter D. Cole, Nancy L. Bartlett, Kevin A. David, Ranjana H. Advani, Richard F. Ambinder, Sachdev Thomas, Sami Ibrahimi, Brad S. Kahl
Journal: Blood (2023)
Immune Reconstitution and Infection Patterns Following CAR T-Cell Therapy in Patients with Aggressive Lymphoma
Authors: Megan Melody, Narendranath Epperla, Geoffrey P. Shouse, Jason T. Romancik, Tamara K. Moyo, Vaishalee P Kenkre, Thomas Ollila, Lindsey Fitzgerald, Brian Hess, Kevin A. David, Kaitlin Annunzio, Megan Herr, Rahul S. Bhansali, Elyse I Harris, James A Davis, Oluwatobi Odetola, Adam Yuh Lin, Jonathan Moreira, Shuo Ma, Jane N. Winter, Deborah M. Stephens, Alexey Danilov, Nirav N. Shah, Ishan Roy, Stefan K. Barta, Matthew J Cortese, Pallawi Torka, Jonathon B. Cohen, Leo I. Gordon, Reem Karmali
Journal: Blood (2023)
High Ki67 Index Is Associated with Shorter Progression Free Survival in Follicular Lymphoma Patients Treated with Frontline Immunochemotherapy
Authors: Jianmin Han, Chad M McCall, Scott Isom, Wesley Smith, Dakota Jenneman, Stephanie Begley, Rupali Bose, Mary Beth Seegars, Eric D. Hsi, Nilanjan Ghosh
Journal: Blood (2023)
Inhibition of Lysine Acetyltransferases p300/CBP Overcomes BTK Inhibitor Resistance in Mantle Cell Lymphoma Cells
Authors: Yusuke Tashiro, Kotaro Shirakawa, Ryosuke Nomura, Yoshihito Horisawa, Stanford Emani, Suguru Takeuchi, Jelagat Caroline, Yasuhiro Kazuma, Kosuke Yusa, Akifumi Takaori-Kondo
Journal: Blood (2023)
Real-World Evidence of Treatment-Free Remission in Chronic Myeloid Leukemia at an Academic Center in the Deep South
Authors: Greg Bascug, Garrett Bourne, Kendall Diebold, Joshua Knapp, Kimo Bachiashvili, Sravanti Rangaraju, Pankit Vachhani, Ravi Bhatia, Omer Jamy
Journal: Blood (2023)
Epigenetic Silencing of CD9 Shapes a New Mechanism to Render Differentiation Block and Immune Evasion in Pediatric Acute Myeloid Leukemia
Authors: Yaqun Xu, Kathy Yuen Yee Chan, Siu Ping Fok, Yixuan Wu, Chi Kong Li, Kam Tong Leung
Journal: Blood (2023)
Self-Association of Von Willebrand Factor (VWF) into Prothrombotic Fibers Is Most Potently Enhanced By the Highly Atherogenic Small, Dense Fraction of Low-Density Lipoprotein (sd-LDL)
Authors: Junmei Chen, Forrest Nussdorfer, Raymond Adili, Kimsey Platten, Nicole Rhoads, Richard Maldonado, Franklin Reed, Yi Wang, Minhua Ling, Sergio Fazio, Xiaoyun Fu, Nathalie Pamir, Jose A. Lopez, Dominic W. Chung
Journal: Blood (2023)
Circulating Tumor DNA (ctDNA) for Plasma Genotyping and Disease Monitoring in ALK-Positive Anaplastic Lymphoma (ALK+ALCL): A Proof of Concept Study
Authors: Damien Vasseur, Samuel Abbou, Ludovic Lacroix, Laurence Lamant, Pata-Merci Noémie, David Sibon, Francesco Facchinetti, Marc Deloger, Floriane Braye, Veronique Minard-Colin, Laurence Brugières, Etienne Rouleau, Luc Friboulet, Charlotte Rigaud
Journal: Blood (2023)
PET4 Response As an Independent Predictor of Long-Term Outcomes in ECHELON2 (A+CHP Vs. CHOP) in CD30+PTCL
Authors: Swami P. Iyer, Neha Mehta-Shah, Ranjana H. Advani, Nancy L. Bartlett, Jacob Haaber Christensen, Frank Morschhauser, EVA Domingo Domenech, Chiara Pagani, Won Seog Kim, Onder Alpdogan, Cheolwon Suh, Tatyana Feldman, Hervé Tilly, Pier Luigi Zinzani, Alessandro Rambaldi, David Belada, Jiri Mayer, Ilseung Choi, June-Won Cheong, Shweta Jain, Fenton Keenan, Michelle A. Fanale, Kerry J. Savage, Steven M. Horwitz
Journal: Blood (2023)
Combination Treatment with Sonrotoclax (BGB-11417), a Second-Generation BCL2 Inhibitor, and Zanubrutinib, a Bruton Tyrosine Kinase (BTK) Inhibitor, Is Well Tolerated and Achieves Deep Responses in Patients with Treatment-Naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (TN-CLL/SLL): Data from an Ongoing Phase 1/2 Study
Authors: Constantine S. Tam, Mary Ann Anderson, Masa Lasica, Emma Verner, Stephen S. Opat, Shuo Ma, Robert Weinkove, Raul Cordoba, Jacob Soumerai, Paolo Ghia, Sophie Leitch, James Hilger, Yiqian Fang, David Simpson, Haiyi Guo, Chan Yoon Cheah
Journal: Blood (2023)
Discovery of a Novel, First-in-Class Bfl-1 BH3 Mimetic with Pro-Apoptotic Activity
Authors: Maarten Derks, Marian C. Bryan, Cindy Rockx, Tamara Schults, Tinne Verhulst, Beth Pietrak, Tatsuya Maehigashi, James C. Robertson, Andrew H. DeMaria, Kimberly Holt, Shaofei Ji, Victoria Wong, Ruud Bueters, Seong Joo Koo, Stefan Masure, Balpreet Bhogal, Christopher B. Kelly, Kaushik Mitra, Leopoldo Luistro, Paul L. Shaffer, Lawrence Szewczuk, Yusri Elsayed, Ulrike Philippar
Journal: Blood (2023)
Single Agent Tagraxofusp in Relapsed/Refractory CD123-Positive Acute Myeloid Leukemia: A Preliminary Analysis of Italian Gimema AML2020 Trial
Authors: Paola Minetto, Sara Rosellini, Fabio Guolo, Elisabetta Tedone, Ernesta Audisio, Chiara Cattaneo, Monica Bocchia, Nicola Fracchiolla, Maria Paola Martelli, Enrico Crea, Enrico Carminati, Livia Gorreo Renzulli, Giuseppina Fugazza, Alfonso Piciocchi, Giovanni Ottonelli, Maurizio Miglino, Michele Cea, Antonio Curti, Livio Pagano, Adriano Venditti, Tariq Mughal, Roberto Massimo Lemoli
Journal: Blood (2023)
The Mechanism of Therapy Resistance By Lineage Plasticity in AML and How to Overcome It
Authors: Sean Walulik, Sarai Dean, Eric J Vick, Xiaoqin Zhu, Mark Wunderlich, Chih-Hsing Chou, Kwangmin Choi, H. Leighton Grimes, Daniel T. Starczynowski, Linde A. Miles, Andrew Volk
Journal: Blood (2023)
IL-6 Mediates a Switch in Free Fatty Acid Metabolism from the Liver to the Bone Marrow to Support HSC Expansion during Infection
Authors: Katherine Hampton, Jayna Mistry, Rebecca S Maynard, Dominic Fowler-Shorten, Charlotte Hellmich, Naiara Beraza, Kristian Bowles, Stuart Rushworth
Journal: Blood (2023)
Durable Clinical Benefits of Idasanutlin Therapy in Hydroxyurea-Refractory Polycythemia Vera
Authors: Julian Waksal, Ronald Hoffman, Abdulraheem Yacoub, Francesco Passamonti, Aaron T. Gerds, Vikas Gupta, Grace Van Hyfte, Jayanshu Jain, Margherita Maffioli, Natalia Rosas, John Mascarenhas
Journal: Blood (2023)
Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone Induction and Consolidation with Tandem Transplant in High-Risk Newly Diagnosed Myeloma Patients: Final Results of the Phase 2 Study IFM 2018-04
Authors: Cyrille Touzeau, Aurore Perrot, Cyrille Hulin, Salomon Manier, Margaret Macro, Marie-Lorraine Chretien, Lionel Karlin, Olivier Decaux, Caroline Jacquet, Mourad Tiab, Xavier Leleu, Jill Corre, Alexandra Jobert, Lucie Planche, Herve Avet-Loiseau, Philippe Moreau
Journal: Blood (2023)
Ixazomib-Based Consolidation and Maintenance Prolongs Progression-Free Survival after Salvage Autologous Stem Cell Transplantation (sASCT): Results from Interim Analysis of UK-MRA Myeloma XII (ACCoRD)
Authors: Gordon Cook, A J Ashcroft, Ethan R Senior, Catherine Olivier, Anna Hockaday, Jeanine Richards, James D. Cavenagh, John Snowden, Mark Drayson, Ruth M de Tute, Roger Owen, Kwee Yong, Mamta Garg, Kevin Boyd, Hamdi Sati, Sharon Gillson, Mark Cook, David Allan Cairns, Christopher Parrish
Journal: Blood (2023)
Optimizing Ex-Vivo Expanded NK Cell- Mediated Cellular Cytotoxicity By Obinutuzumab Combined with NKTR-255 in Burkitt Lymphoma (BL)
Authors: Yaya Chu, Keira Foley, Meijuan Tian, Kayleigh Klose, Jessica Ayala-Cuesta, Dean Anthony Lee, Mario Marcondes, Christian Klein, Mitchell S. Cairo
Journal: Blood (2023)
The Prognostic Impact of Body Composition Assessment By Computed Tomography in Adult Patients with Newly Diagnosed Acute Lymphoblastic Leukemia
Authors: Fausto Alfredo Rios Olais, Fernando Gil-Lopez, Analy Mora, Jessica Zalapa, Guillermo Rosales-Sotomayor, Alejando Gabutti-Thomas, Roberta Demichelis
Journal: Blood (2023)
Diagnosis to Treatment Interval (DTI) Informs Outcomes across Subtypes of Aggressive B-Cell Lymphoma
Authors: Matthew J. Maurer, Arushi Khurana, Raphael Mwangi, Grzegorz S. Nowakowski, Carla Casulo, Dai Chihara, Jonathon B. Cohen, Brad S. Kahl, Izidore S. Lossos, Peter Martin, Yucai Wang, Timothy J. McDonnell, Andrew L. Feldman, David L Jaye, Thomas M. Habermann, James R. Cerhan, Christopher R. Flowers, Brian K. Link, Loretta J. Nastoupil
Journal: Blood (2023)
Monotherapy with Second-Generation BCL2 Inhibitor Sonrotoclax (BGB-11417) Is Well Tolerated with High Response Rates in Patients with Relapsed/Refractory Marginal Zone Lymphoma: Data from an Ongoing Phase 1 Study
Authors: Alessandra Tedeschi, Chan Yoon Cheah, Stephen S. Opat, Emma Verner, Laura Magnano, Narendranath Epperla, James Hilger, Yiqian Fang, David Simpson, Haiyi Guo, Mary Ann Anderson
Journal: Blood (2023)
Emicizumab Versus Immunosuppression for Acquired Hemophilia Α (AHA)
Authors: Christina Hart, Robert Klamroth, Ulrich J. Sachs, Richard Greil, Paul N. Knoebl, Johannes Oldenburg, Wolfgang Miesbach, Christian Pfrepper, Karolin Trautmann-Grill, Isabell Pekrul, Katharina Holstein, Hermann Eichler, Carmen Weigt, Dorothea Schipp, Sonja Werwitzke, Andreas Tiede
Journal: Blood (2023)
Title: Risk Factors and Natural History of Vincristine Induced Neuropathy on UKALL 2011: A Randomised Controlled Trial of the Effect of Omitting Vincristine Pulses
Authors: Lucy Alderson, Lucy Waller, Mario Cortina Borja, Amy A Kirkwood, Vickaynne Carruthers, David Jamieson, Pam Kearns, Amrana Qureshi, Susan Baird, Jayashree Motwani, Rachael Hough, John Moppett, Ajay Vora, Gareth Veal, Sujith Samarasinghe
Journal: Blood (2023)
Marsun, a Phase III, Multicenter, Open Label, Randomized, Controlled Study Investigating Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients with Relapsed or Refractory Marginal Zone Lymphoma (R/R MZL)
Authors: Catherine Thieblemont, Annarita Conconi, Christian Buske, Stefano Luminari, Martin Dreyling, Maria Gomes da Silva, Marc Andre, Maria Flores, Karima Brahami-Aissou, Pascale Cony-Makhoul, Sylvain Carras
Journal: Blood (2023)
Postinfusion Monitoring Health Care Resource Utilization and Costs By Site of Care Among Inpatients and Outpatients with Relapsed or Refractory Large B-Cell Lymphoma Who Received Second-Line Treatment with Lisocabtagene Maraleucel in the TRANSFORM and PILOT Clinical Trials
Authors: November McGarvey, Matthew Gitlin, Abraham Lee, Scott J. Keating, Victoria Barghout, Simran K. Tiwana
Journal: Blood (2023)
Deciphering the Clinical Benefit of Pola-R-CHP versus R-CHOP in Different Genetic Subtypes Beyond Cell of Origin in the POLARIX Study
Authors: Franck Morschhauser, Wilfred Leung, Vibha Raghavan, Georg Lenz, Fabrice Jardin, Alex F. Herrera, Laurie H. Sehn, Jeff P. Sharman, Christopher R. Flowers, Jonathan W. Friedberg, Marek Trněný, Hervé Tilly, Charles Herbaux, Samuel Tracy, Christopher R. Bolen, Will Harris, Jamie H. Hirata, Calvin Lee, Yanwen Jiang, Gilles Salles
Journal: Blood (2023)
Functional Characterization and Optimization of Switchable Allogeneic Chimeric Antigen Receptor T Cells for Targeting CD19 and CD20 in B Cell Malignancies
Authors: Johannes Spehr, Jan-Erik Meyer, Simon Loff, Anika Langer, Moritz Langer, Ben Boyerinas, Isabelle Le Mercier, Reynald Lescarbeau, Marc Cartellieri, Armin Ehninger
Journal: Blood (2023)
Characteristics and Trends of Hospitalizations for Sickle-Cell Related Complications
Authors: Suma Sri Chennapragada, Sindhu Thevuthasan, Saloni Savani, Shriya Goyal, Vaishnavi Singh, Kamleshun Ramphul, Hemamalini Sakthivel, Shivani Sharma, Arcita Hanjani Pramudita, Poornima Ramadas
Journal: Blood (2023)
Applicability of SIE/Sies/GITMO Fitness Criteria to Therapy-Related and AML-MRC Receiving CPX-351: Results from a Large, Retrospective, Multicentric, Observational Study
Authors: Raffaele Palmieri, Fabio Guolo, Luana Fianchi, Felicetto Ferrara, Maria Paola Martelli, Michela Rondoni, Capria Saveria, Paola Minetto, Clara Minotti, Sofia Sciabolacci, Federica Pilo, Salvatore Perrone, Andrea Corbingi, Francesco Grimaldi, Giulia De Luca, Carla Fili, Caterina Alati, Francesco Mannelli, Federica Lessi, Francesco Marchesi, Lorenzo Brunetti, Debora Capelli, Anna Lina Piccioni, Calogero Vetro, Carla Mazzone, Alessandra Sperotto, Giovanni Luzi, Michelina Dargenio, Sabrina Mariani, Marco Cerrano, Antonino Mulè, Ambra Di Veroli, Cristina Papayannidis, Alessandro Isidori, Francesco Lanza, Michele Gottardi, Elisabetta Todisco, Livio Pagano, Roberto Massimo Lemoli, Francesco Buccisano, Adriano Venditti
Journal: Blood (2023)
Update Results of a Phase II Trial of Venetoclax in Combination with Azacitidine and Chidamide in Relapsed/Refractory Acute Myeloid Leukemia
Authors: Jie Zha, Ying Wang, Zhenling Li, Zhijuan Lin, Yun Cai, Tiejun Gong, Wei Yang, Siting Xie, Zhenqi Huang, Pengcheng SHI, Lin Fu, Jinghua Wang, Xiangjun Fu, Xianqi Feng, Liping Su, Jianmin Luo, Lin Yang, Biyun Chen, Ying Xie, Yu Zhu, Xin Du, Yirong Jiang, Zhifeng Li, Bing Xu
Journal: Blood (2023)
Takeaim Lymphoma: An Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Combination with Ibrutinib in Patients with Relapsed or Refractory Hematologic Malignancies
Authors: Christian Grommes, Han Tun, Allison C. Rosenthal, Matthew A Lunning, Radhakrishnan Ramchandren, Lucia Regales, Wanying Zhao, Maureen Lane, Catherine Wang, Reinhard von Roemeling, Iris Isufi, Lori A. Leslie, Grzegorz S. Nowakowski
Journal: Blood (2023)
Sgr-1505 Is a Potent MALT1 Protease Inhibitor with a Potential Best-in-Class Profile
Authors: Wu Yin, Min Ye, Netonia Marshall, Joanne BL Tan, Evan Paull, Zhe Nie, MIchael Trzoss, Goran Krilov, Shulu Feng, Robert Pelletier, Jeff Bell, Peter Skrdla, David Calkins, MaryBeth Grimes, D. Hamish Wright, Karen Akinsanya
Journal: Blood (2023)
Whole-Exome Sequencing Among School-Aged Children With High Myopia
Authors: Xiangyi Yu, Jian Yuan, Zhen Ji Chen, Kai Li, Yinghao Yao, Shilai Xing, Zhengbo Xue, Yue Zhang, Hui Peng, Gang An, Xiaoguang Yu, Jia Qu, Jianzhong Su, Liangde Xu, Hong Wang, Meng Zhou, Jie Sun, Hao Chen, Fan Lyu, Xinting Liu, Jinhua Bao, Nan Wu
Journal: JAMA Network Open (2023)

Importance High myopia (HM) is one of the leading causes of visual impairment worldwide. Genetic factors are known to play an important role in the development of HM. Objective To identify risk variants in a large HM cohort and to examine the implications of genetic testing of schoolchildren with HM. Design, Setting, and Participants This cohort study retrospectively reviewed whole-exome sequencing (WES) results in 6215 schoolchildren with HM who underwent genetic testing between September 2019 and July 2020 in Wenzhou City, China. HM is defined as a spherical equivalent refraction (SER) of −6.00 diopters (D) or less. The study setting was a genetic testing laboratory and a multicenter school census. Data were analyzed from July 2021 to June 2022. Main Outcomes and Measures The frequency and distribution of positive germline variants, the percentage of individuals with HM in both eyes, and subsequent variant yield for common high myopia (CHM; −8.00 D ≤ SER ≤ −6.00 D), ultra myopia (UM; −10.00 D ≤ SER &amp;amp;lt; −8.00 D), and extreme myopia (EM; SER &amp;amp;lt; −10.00 D). Results Of the 6215 schoolchildren with HM, 3278 (52.74%) were male. Their mean (SD) age was 14.87 (2.02) years, including 355 students in primary school, 1970 in junior high school, and 3890 in senior high school. The mean (SD) SER was −7.51 (−1.36) D for the right eye and −7.46 (−1.34) D for the left eye. Among schoolchildren with HM, genetic testing yielded 271 potential pathogenic variants in 75 HM candidate genes in 964 diagnoses (15.52%). A total of 36 known variants were found in 490 HM participants (7.88%) and 235 protein-truncating variants (PTVs) in 506 participants (8.14%). Involved variant yield was significantly positively associated with SER (Cochran-Armitage test for trend Z = 2.5492; P = .01), which ranged from 7.66% in the CHM group, 8.70% in the UM group, to 11.90% in the EM group. We also found that primary school students with EM had the highest variant yield of PTVs (8 of 35 students [22.86%]), which was 1.77 and 4.78 times that of the UM and CHM, respectively. Conclusions and Relevance In this cohort study of WES for HM, several potential pathogenic variants were identified in a substantial number of schoolchildren with HM. The high variation frequency in younger students with EM can provide clues for genetic screening and clinical examinations of HM to promote long-term follow-up assessment.
Highly Sensitive Interleukin Score for Intra-Ocular Lymphoma Diagnosis: Evidence from Analysis of 5-Year Real-Life of Use
Authors: Elise Sourdeau, Martin Chevalier, Hélène Masse, Julie Gueudry, Yann Maucourant, Marie-Laure Le Lez, Philippe Gohier, Marie Alice Laville, Nathalie Cassoux, Fatma Abid Mzid, Mohamed Ali Gargouri, Marie Marechal, Guido Ahle, Clotilde Devin, Sara Touhami, Valerie Touitou, Caroline Houillier, Khe Hoang-Xuan, Choquet Sylvain, Carole Soussain, Adélaïde Toutee, Magali Le Garff-Tavernier
Journal: Blood (2023)
Phase I Trial Combining Venetoclax with G-CSF, Cladribine, Cytarabine, and Mitoxantrone (CLAG-M) for Patients with High-Grade Myeloid Neoplasms
Authors: Suravi Raychaudhuri, Ted Gooley, Zach Gill, Allegra Rasmussen, Anna B. Halpern, Jacob S. Appelbaum, Cristina Maria Ghiuzeli, Paul C. Hendrie, Ryan D Cassaday, Roland B. Walter, Elihu Estey, Mary-Elizabeth M. Percival
Journal: Blood (2023)
Categorization of Hematological Responses to Oral Iptacopan Monotherapy in Anti-C5-Treated Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) and Persistent Anemia in the Phase III APPLY-PNH Trial and Complement Inhibitor-Naïve Patients in the Phase III APPOINT-PNH Trial
Authors: Antonio M Risitano, Bing Han, Austin Kulasekararaj, Yasutaka Ueda, Phillip Scheinberg, Carlos de Castro, Jaroslaw P. Maciejewski, Josefin Snellman, Ranjan Tiwari, Marion Dahlke, Régis Peffault de Latour
Journal: Blood (2023)
Decitabine Combined with Low-Dose Chemotherapy Is Effective in the Treatment of Pediatric Refractory/Relapsed Acute Myeloid Leukemia
Authors: Liyan Fan, Hua Jiang, Hongjun Liu, Ning Liao, Ningling Wang, Xiaowen Zhai, Xiuli Ju, Yufeng Liu, Jixia Luo, Peifang Xiao, Jun Lu, Hailong He, Yi Wang, Raul C. Ribeiro, Shaoyan Hu
Journal: Blood (2023)
Novel Bone Marrow/HSC-Targeted, Megakaryocyte-Derived Extracellular Vesicle Delivery Modality for <i>In Vivo</i> Gene Therapy
Authors: Laura R Goldberg, Qiuyan W Ma, Navdeep Malik, Daniel Bode, Samik Das, Will Thompson, Jenna C Harris, Joseph R Inigo, Pragati Jain, Emily S Day, David M Raiser, Sedattin S Ozturk, Eleftherios T Papoutsakis, Iain R Thompson, Jonathan N. Thon
Journal: Blood (2023)
Biomarker Correlates of Response to Ciltacabtagene Autoleucel in Patients with Relapsed or Refractory Multiple Myeloma from CARTITUDE-1, a Phase 1b/2 Open-Label Study, at the ~3 Year Follow-up
Authors: Rocio Montes de Oca, Junchen Gu, Hao Zhao, Kathy Zelinsky, Dianna Wu, Cuc Davis, Jaymala Patel, Brad Foulk, Rengasamy Boominathan, Onsay Lau, Denis Smirnov, Yi Lin, Sundar Jagannath, Adam D. Cohen, Nahor Haddish-Berhane, Jean Xu, Deepu Madduri, An-Sofie Stevens, Carolyn Chang Jackson, Jordan M. Schecter, Arnob Banerjee, Dong Geng, Jieqing Zhu, Sifan Xu, Enrique Zudaire
Journal: Blood (2023)
Quality of Life with Nivolumab and AVD First-Line Treatment in Hodgkin Lymphoma: Patient-Reported Outcomes from the Phase II GHSG Nivahl Trial
Authors: Paul J Bröckelmann, Ina Bühnen, Peter Herhaus, Julia Meissner, Karolin Trautmann-Grill, Horst Müller, Michael Fuchs, Bastian von Tresckow, Peter Borchmann, Andreas Engert, Karolin Behringer
Journal: Blood (2023)
Validating the Systemic Inmmune-Inflamation Index (SII) As a Prognostic Biomarker of Overall Survival in Diffuse Large B-Cell Lymphoma: A Retrospective Analyses By the Gruppo De Estudio Latinoamericano De Linfoproliferativos (GELL)
Authors: Luis Mario Villela Martinez, Brady E Beltran, Myrna Candelaria, Ana Florencia Ramirez, Marialejandra Torres Viera, Carolina Oliver, Henry Idrobo Quintero, Fernando perez-Jacobo, Arianna Robles Rodriguez, Guilherme F Perini, Camila Peña, Laura Korin, Denisse Castro, Victoria Irigoín, Sally Rose Paredes, Jose A Hernandez-Hernandez, Perla R. Colunga-Pedraza, David Gomez-Almaguer, Guillermo Ruiz-Argüelles, Melani Otañez, Rosa Oliday Rios Jiménez, Carlos Gil Rondero, Jorge J. Castillo, Fabiola Valvert, Luis Malpica
Journal: Blood (2023)
Single-Cell Longitudinal Characterization of FL Heterogeneity and Residual Disease in the Bone Marrow from Low-Tumor Burden FL Enrolled in the Flirt Clinical Trial
Authors: Alicia Beyou, Simon Leonard, Ilenia Papa, Noushin Mossadegh-Keller, Sabrina Baaklini, Lionel Spinelli, Owen Hoare, Bertrand Nadel, Pierre Milpied, Joëlle Dulong, Céline Monvoisin, Gabriel Brisou, Guillaume Cartron, Karin Tarte, Sandrine Roulland
Journal: Blood (2023)
Efficacy and Safety of TLR2 Co-Stimulated CAR T Cells in CD19-Positive Lymphoid Malignancies with Central Nervous System Involvement
Authors: Bailin He, Hongsheng Zhou, Ren Lin, Zhixiang Wang, Na Xu, Qiang Wang, Jing Sun, Xiaoli Liu, Peng Li, Qifa Liu
Journal: Blood (2023)
Gemtuzumab Ozogamicin for Patients with Newly Diagnosed CD33 Positive Acute Myeloid Leukemia: Results from a French Retrospective Observational Study
Authors: Juliette Lambert, Emmanuel Raffoux, Delphine Lebon, Thorsten Braun, Mael Heiblig, Alberto Santagostino, Karin Gogat-Marchant, Cécile Pautas
Journal: Blood (2023)
Clinical Factors Associated with Cytokine Release Syndrome and Dosing Recommendations for Restarting Elranatamab Following an Interruption
Authors: Ruben Niesvizky, Bertrand Arnulf, Mohamad Mohty, Ajay K. Nooka, Salomon Manier, Michael Tomasson, Nizar J Bahlis, Donald Irby, Jennifer Hibma, Andrea Viqueira, Eric Leip, Alexander Lesokhin
Journal: Blood (2023)
Characterizing Inferred Functional and Phenotypical States of Newly Diagnosed Acute Myeloid Leukemia from Single Cell Transcriptomic Profiling
Authors: Bofei Wang, Christopher Ly, Enes Dasdemir, Fatima Z Jelloul, Poonam N Desai, Pamella Borges, Jessica Lynn Root, Guilin Tang, Preethi Gunaratne, Sreyashi Basu, Sonali Jindal, Yulong Chen, Khalida M Wani, Alexander J Lazar, Padmanee Sharma, Patrick K Reville, Hussein A Abbas
Journal: Blood (2023)
CD117 Antibody-Drug Conjugate Conditioning Allows Efficient Engraftment of Gene-Modified CD34+ Cells with Fertility Preservation in a Rhesus Gene Therapy Model
Authors: Naoya Uchida, Selami Demirci, Anh Le, Rebecca Chu, Xiong Liu, Ling Su, Xiaolin Wu, Allen Krouse, N Seth Linde, Aylin Bonifacino, So Gun Hong, Cynthia E. Dunbar, Leanne Lanieri, Anjali Bhat, Rahul Palchaudhuri, Bindu Bennet, Megan D. Hoban, Kirk Bertelsen, Lisa Olson, Robert Donahue, John F. Tisdale
Journal: Blood (2023)
Blood-Based Diagnostic Assay for λ Light Chain Amyloidosis through Quantification of an Amyloidogenicity-Indicating Neo-Epitope
Authors: Xin Jiang, Jianying Wang, Yao-Cheng Li, Alexander B Jackman, Hannah Flaherty, Imani Rogers, Eli Muchtar, Angela Dispenzieri, Brian H Spencer, Vaishali Sanchorawala, Tatiana Prokaeva, Richard Labaudiniere
Journal: Blood (2023)
Cellular Barcoding of <i>JAK2</i>-V617F Hematopoietic Stem Cells Reveals No Substantial Preferences in the Contribution of Individual Stem Cell Clones to Erythroid Versus Megakaryocytic Lineages
Authors: Marc Usart, Tiago Almeida, Julien Roux, Athimed El Taher, Riikka Karjalainen, Quentin Kimmerlin, Shivam Rai, Hui Hao-Shen, Radek C. Skoda
Journal: Blood (2023)