Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific Mortality
Authors: Kouji H. Harada, Mariko Harada Sassa
Journal: Annals of Internal Medicine (2023)

LettersJanuary 2023Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific MortalityKouji H. Harada, PhD, MPH and Mariko Harada Sassa, MD, PhDKouji H. Harada, PhD, MPHKyoto University Graduate School of Medicine, Kyoto, JapanSearch for more papers by this author and Mariko Harada Sassa, MD, PhDKyoto University Graduate School of Medicine, Kyoto, JapanSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L22-0368 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR: Liu and colleagues (1) used data from the UK Biobank to analyze the relationship between coffee consumption and mortality, stratified by whether sugar or artificial sweeteners were added. They found that moderate coffee consumption with and without sugar was associated with lower all-cause and cancer mortality.These findings are consistent with Loftfield and associates' analysis of UK Biobank data (2), which reported a mild reduction in mortality with coffee consumption. However, in another analysis of UK Biobank data by Ong and coworkers (3), an observational study reported in conjunction with a Mendelian randomization study found almost no ...References1. Liu D, Li ZH, Shen D, et al. Association of sugar-sweetened, artificially sweetened, and unsweetened coffee consumption with all-cause and cause-specific mortality. A large prospective cohort study. Ann Intern Med. 2022;175:909-17. [PMID: 35635846] doi:10.7326/M21-2977 LinkGoogle Scholar2. Loftfield E, Cornelis MC, Caporaso N, et al. Association of coffee drinking with mortality by genetic variation in caffeine metabolism: findings from the UK biobank. JAMA Intern Med. 2018;178:1086-97. [PMID: 29971434] doi:10.1001/jamainternmed.2018.2425 CrossrefMedlineGoogle Scholar3. Ong JS, Law MH, An J, et al. Association between coffee consumption and overall risk of being diagnosed with or dying from cancer among > 300 000 UK Biobank participants in a large-scale Mendelian randomization study. Int J Epidemiol. 2019;48:1447-56. [PMID: 31412118] doi:10.1093/ije/dyz144 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Kyoto University Graduate School of Medicine, Kyoto, JapanDisclosures: Authors have reported no disclosures of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L22-0368. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAssociation of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific Mortality Dan Liu , Zhi-Hao Li , Dong Shen , Pei-Dong Zhang , Wei-Qi Song , Wen-Ting Zhang , Qing-Mei Huang , Pei-Liang Chen , Xi-Ru Zhang , and Chen Mao Association of Sugar-Sweetened, Artificially Sweetened, and Unsweetened Coffee Consumption With All-Cause and Cause-Specific Mortality Dan Liu , Qingmei Huang , Weiqi Song , Zhihao Li , and Chen Mao Metrics January 2023Volume 176, Issue 1KeywordsBiobanksCardiovascular diseasesCoffeeDietExerciseHypertensionMortalityPrevention, policy, and public healthQuestionnaires ePublished: 17 January 2023 Issue Published: January 2023 Copyright & PermissionsCopyright © 2023 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...