Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Authors: Anubha Mahajan, Cassandra N. Spracklen, Weihua Zhang, Maggie C. Y. Ng, Lauren E. Petty, Hidetoshi Kitajima, Grace Z. Yu, Sina Rüeger, Leo Speidel, Young Jin Kim, Momoko Horikoshi, Josep M. Mercader, Daniel Taliun, Sanghoon Moon, Soo-Heon Kwak, Neil R. Robertson, Nigel W. Rayner, Marie Loh, Bong-Jo Kim, Joshua Chiou, Irene Miguel-Escalada, Pietro della Briotta Parolo, Kuang Lin, Fiona Bragg, Michael H. Preuss, Fumihiko Takeuchi, Jana Nano, Xiuqing Guo, Amel Lamri, Masahiro Nakatochi, Robert A. Scott, Jung-Jin Lee, Alicia Huerta-Chagoya, Mariaelisa Graff, Jin-Fang Chai, Esteban J. Parra, Jie Yao, Lawrence F. Bielak, Yasuharu Tabara, Yang Hai, Valgerdur Steinthorsdottir, James P. Cook, Mart Kals, Niels Grarup, Ellen M. Schmidt, Ian Pan, Tamar Sofer, Matthias Wuttke, Chloe Sarnowski, Christian Gieger, Darryl Nousome, Stella Trompet, Jirong Long, Meng Sun, Lin Tong, Wei-Min Chen, Meraj Ahmad, Raymond Noordam, Victor J. Y. Lim, Claudia H. T. Tam, Yoonjung Yoonie Joo, Chien-Hsiun Chen, Laura M. Raffield, Cécile Lecoeur, Bram Peter Prins, Aude Nicolas, Lisa R. Yanek, Guanjie Chen, Richard A. Jensen, Salman Tajuddin, Edmond K. Kabagambe, Ping An, Anny H. Xiang, Hyeok Sun Choi, Brian E. Cade, Jingyi Tan, Jack Flanagan, Fernando Abaitua, Linda S. Adair, Adebowale Adeyemo, Carlos A. Aguilar-Salinas, Masato Akiyama, Sonia S. Anand, Alain Bertoni, Zheng Bian, Jette Bork-Jensen, Ivan Brandslund, Jennifer A. Brody, Chad M. Brummett, Thomas A. Buchanan, Mickaël Canouil, Juliana C. N. Chan, Li-Ching Chang, Miao-Li Chee, Ji Chen, Shyh-Huei Chen, Yuan-Tsong Chen, Zhengming Chen, Lee-Ming Chuang, Mary Cushman, Swapan K. Das, H. Janaka de Silva, George Dedoussis, Latchezar Dimitrov, Ayo P. Doumatey, Shufa Du, Qing Duan, Kai-Uwe Eckardt, Leslie S. Emery, Daniel S. Evans, Michele K. Evans, Krista Fischer, James S. Floyd, Ian Ford, Myriam Fornage, Oscar H. Franco, Timothy M. Frayling, Barry I. Freedman, Christian Fuchsberger, Pauline Genter, Hertzel C. Gerstein, Vilmantas Giedraitis, Clicerio González-Villalpando, Maria Elena González-Villalpando, Mark O. Goodarzi, Penny Gordon-Larsen, David Gorkin, Myron Gross, Yu Guo, Sophie Hackinger, Sohee Han, Andrew T. Hattersley, Christian Herder, Annie-Green Howard, Willa Hsueh, Mengna Huang, Wei Huang, Yi-Jen Hung, Mi Yeong Hwang, Chii-Min Hwu, Sahoko Ichihara, Mohammad Arfan Ikram, Martin Ingelsson, Md Tariqul Islam, Masato Isono, Hye-Mi Jang, Farzana Jasmine, Guozhi Jiang, Jost B. Jonas, Marit E. Jørgensen, Torben Jørgensen, Yoichiro Kamatani, Fouad R. Kandeel, Anuradhani Kasturiratne, Tomohiro Katsuya, Varinderpal Kaur, Takahisa Kawaguchi, Jacob M. Keaton, Abel N. Kho, Chiea-Chuen Khor, Muhammad G. Kibriya, Duk-Hwan Kim, Katsuhiko Kohara, Jennifer Kriebel, Florian Kronenberg, Johanna Kuusisto, Kristi Läll, Leslie A. Lange, Myung-Shik Lee, Nanette R. Lee, Aaron Leong, Liming Li, Yun Li, Ruifang Li-Gao, Symen Ligthart, Cecilia M. Lindgren, Allan Linneberg, Ching-Ti Liu, Jianjun Liu, Adam E. Locke, Tin Louie, Jian’an Luan, Andrea O. Luk, Xi Luo, Jun Lv, Valeriya Lyssenko, Vasiliki Mamakou, K. Radha Mani, Thomas Meitinger, Andres Metspalu, Andrew D. Morris, Girish N. Nadkarni, Jerry L. Nadler, Michael A. Nalls, Uma Nayak, Suraj S. Nongmaithem, Ioanna Ntalla, Yukinori Okada, Lorena Orozco, Sanjay R. Patel, Mark A. Pereira, Annette Peters, Fraser J. Pirie, Bianca Porneala, Gauri Prasad, Sebastian Preissl, Laura J. Rasmussen-Torvik, Alexander P. Reiner, Michael Roden, Rebecca Rohde, Kathryn Roll, Charumathi Sabanayagam, Maike Sander, Kevin Sandow, Naveed Sattar, Sebastian Schönherr, Claudia Schurmann, Mohammad Shahriar, Jinxiu Shi, Dong Mun Shin, Daniel Shriner, Jennifer A. Smith, Wing Yee So, Alena Stančáková, Adrienne M. Stilp, Konstantin Strauch, Ken Suzuki, Atsushi Takahashi, Kent D. Taylor, Barbara Thorand, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Brian Tomlinson, Jason M. Torres, Fuu-Jen Tsai, Jaakko Tuomilehto, Teresa Tusie-Luna, Miriam S. Udler, Adan Valladares-Salgado, Rob M. van Dam, Jan B. van Klinken, Rohit Varma, Marijana Vujkovic, Niels Wacher-Rodarte, Eleanor Wheeler, Eric A. Whitsel, Ananda R. Wickremasinghe, Ko Willems van Dijk, Daniel R. Witte, Chittaranjan S. Yajnik, Ken Yamamoto, Toshimasa Yamauchi, Loïc Yengo, Kyungheon Yoon, Canqing Yu, Jian-Min Yuan, Salim Yusuf, Liang Zhang, Wei Zheng, Sina Rüeger, Pietro della Briotta Parolo, Yoonjung Yoonie Joo, M. Geoffrey Hayes, Leslie J. Raffel, Michiya Igase, Eli Ipp, Susan Redline, Yoon Shin Cho, Lars Lind, Michael A. Province, Craig L. Hanis, Patricia A. Peyser, Erik Ingelsson, Alan B. Zonderman, Bruce M. Psaty, Ya-Xing Wang, Charles N. Rotimi, Diane M. Becker, Fumihiko Matsuda, Yongmei Liu, Eleftheria Zeggini, Mitsuhiro Yokota, Stephen S. Rich, Charles Kooperberg, James S. Pankow, James C. Engert, Yii-Der Ida Chen, Philippe Froguel, James G. Wilson, Wayne H. H. Sheu, Sharon L. R. Kardia, Jer-Yuarn Wu, M. Geoffrey Hayes, Ronald C. W. Ma, Tien-Yin Wong, Leif Groop, Dennis O. Mook-Kanamori, Giriraj R. Chandak, Francis S. Collins, Dwaipayan Bharadwaj, Guillaume Paré, Michèle M. Sale, Habibul Ahsan, Ayesha A. Motala, Xiao-Ou Shu, Kyong-Soo Park, J. Wouter Jukema, Miguel Cruz, Roberta McKean-Cowdin, Harald Grallert, Ching-Yu Cheng, Erwin P. Bottinger, Abbas Dehghan, E-Shyong Tai, Josée Dupuis, Norihiro Kato, Markku Laakso, Anna Köttgen, Woon-Puay Koh, Colin N. A. Palmer, Simin Liu, Goncalo Abecasis, Jaspal S. Kooner, Ruth J. F. Loos, Kari E. North, Christopher A. Haiman, Jose C. Florez, Danish Saleheen, Torben Hansen, Oluf Pedersen, Reedik Mägi, Claudia Langenberg, Nicholas J. Wareham, Shiro Maeda, Takashi Kadowaki, Juyoung Lee, Iona Y. Millwood, Robin G. Walters, Kari Stefansson, Simon R. Myers, Jorge Ferrer, Kyle J. Gaulton, James B. Meigs, Karen L. Mohlke, Anna L. Gloyn, Donald W. Bowden, Jennifer E. Below, John C. Chambers, Xueling Sim, Michael Boehnke, Jerome I. Rotter, Mark I. McCarthy, Andrew P. Morris
Journal: Nature Genetics (2022)