tbuckley/cabot-search huggingface dataset:
Wiener Klinische Wochenschrift
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Deaths From Hypothermia
Authors: Ross E. Zumwalt
Journal: JAMA (1986)

<h3>To the Editor.—</h3> The mortality data for hypothermia-associated deaths based on death certificates in the Jan 17 issue of<i>JAMA</i><sup>1</sup>do not accurately represent the true incidence of either primary or secondary hypothermia, particularly in the elderly. We reviewed medical records of ward deaths of elderly patients in a large university hospital during two successive winters and identified six delayed deaths (24 hours to 16 days) following admission with hypothermia. Rectal temperatures on arrival to the emergency unit ranged from 24°C to 35°C (75°F to 95°F). There were three men and three women between 79 and 91 years of age. Investigations of the circumstances surrounding the admissions indicated the cause of hypothermia as primary in three instances and secondary in the other three. In three of the six instances (one primary and two secondary) hypothermia was not considered by the treating physician as the cause of death or a
Thromboembolism and Oral Contraceptives
Authors: Arthur F. Johnson
Journal: JAMA (1972)

<h3>To the Editor.—</h3> The article by Drill and Calhoun (219:583, 1972) and subsequent comments (220:416, 1972, and 221:194, 1972) on the problem of thromboembolic episodes and oral contraceptives consider at length the problems of retrospective and prospective studies. If the critical standards presented had been applied to the articles cited by Drill and Calhoun, there would not have been much left to discuss. The citations of Goldzieher and of Tyler, for example, are not to research reports but to short sections of articles of a very general nature. Tyler's comments are not even quantitative. Ten of the 15 articles cited by Drill and Calhoun in their principle tabulation (Table 3) were readily available to me. When I arranged these articles in order of scientific merit as regards the embolism problem, it became apparent that the better the quality of the scientific effort, the higher was the reported incidence of thromboembolism
The "Cradle-Books" of Medicine
Authors: Dorothy M. Schullian
Journal: JAMA (1966)

The Latin word<i>cunae</i>, meaning cradle, has given us the English term incunable (Latin<i>incunabulum</i>) to designate the earliest books which were printed from movable type from the time of Gutenberg to the close of the year 1500. Here were texts, whether of earlier or current treatises, reproduced in a quantity and with an accuracy never possible in manuscript. And they were reproduced by hardheaded, profit-minded publishers, reproduced therefore to be<i>bought</i>and<i>read</i>and<i>used</i>. Among the new books few could have been more practical than those of medical content. Small wonder then that physicians bought them, consulted them, studied them, annotated them, accumulated libraries of them. It was an age when information was avidly sought, whether in Greek, Latin, Italian, German, French, or Spanish. Accordingly, any physician who reads their languages today will realize that he should value these books not primarily because they are now museum pieces,
Images Gleaned at Radiologists' Annual Meeting
Authors: Andrew A. Skolnick
Journal: JAMA (1996)

AMONG THE diverse presentations at the 81st Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA) in Chicago, Ill, were a method for securing the privacy of transmitted medical images, a diagnostic procedure that may save patients with "skier's thumb" from undergoing unnecessary surgery, an experimental surgical technique that someday may allow gastrointestinal operations to be performed without general anesthesia or an abdominal incision, and methods to improve detection of domestic violence. <h3>Securing Medical Images</h3> Researchers at the University of California, San Francisco, have developed a security system to prevent unauthorized persons from viewing or tampering with radiological images transmitted over computer networks. The system, which was developed by Stephen T. C. Wong, PhD, assistant professor of radiology and bioengineering, and colleagues will protect medical images that are transmitted to other departments within a hospital or to remote sites. "An unresolved issue of transmitting medical images
Large Intestinal Carcinogenesis. II. Histogenesis and Unusual Features of Low-Dose Azoxymethane-Induced Carcinomas in F344 Rats&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;
Journal: JNCI Journal of the National Cancer Institute (1984)

The histogenesis of large intestinal carcinomas was studied by use of a low dose (2 mg/kg/wk) of azoxymethane [(AOM) CAS: 25843-45-2] administered im to inbred F344 rats. No evidence of benign polyp was seen, and the carcinomas in this model did arise directly from the flat mucosa. In marked contrast to the standard dose (8 mg/kg/wk) studies, low-dose AOM carcinogenesis yielded the following unusual features: a) There was a very high incidence of readily metastasizing mucinous adenocarcinomas that were extremely aggressive and easily transplantable; b) the carcinomas, microscopic and macroscopic, were localized predominantly in the proximal large intestine; c) foci of atypical early neoplastic (or so-called dysplastic) crypts as well as early carcinomas were frequently associated with the lymphoid aggregates in the intestinal wall; d) Paneth cells were commonly seen to be associated with these atypical crypts and/or early carcinomas associated with the lymphoid aggregates; and e) there was a virtual lack of the dilated, distorted, or hyperdistended crypts in noncarcinomatous epithelia. The significance of the lack of dilated, distorted, hyperdistended crypts and the similarity of this finding with the findings in the low incidence of colon cancer in the Japanese population are discussed.
Ascites and Cardiac Failure in a Diabetic Man
Authors: James G. Flournoy
Journal: JAMA (1983)

<h3>History</h3> A 55-year-old man was admitted with increasing abdominal girth and deteriorating mental status over a one-month period. His medical history included the presence of diabetes mellitus, congestive heart failure, and degenerative arthritis. No history of alcohol abuse was obtained. The history indicated that two siblings had similar, although less severe, complaints. Physical examination revealed a cachetic man, with a metallic gray color to the skin. Tense ascites was noted, but no hepatosplenomegaly. Both testicles were atrophic. Figure 1 is an anteroposterior roentgenogram of the abdomen, Fig 2 is an unenhanced computed tomographic (CT) scan, and Fig 3 is a roentgenogram of the right hand and wrist (oblique). <h3>Diagnosis</h3> Primary hemochromatosis. <h3>Comment</h3> Both Figs 1 and 2 demonstrate a dense and markedly contracted liver in association with massive ascites. Increased attenuation of the spleen also is present on the CT scan. A single calcified gallstone and adynamic ileus are additional
The Cost of Sickness and the Price of Health
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Expression of intercellular adhesion molecule 1 in human hepatocellular carcinoma
Authors: Seiya Momosaki, Hirohisa Yano, Sachiko Ogasawara, Koichi Higaki, Tohru Hisaka, Masamichi Kojiro
Journal: Hepatology (1995)

We investigated the expression of intercellular adhesion molecule 1 (ICAM-1) in ex vivo human hepatocellular carcinoma (HCC) cells and in vitro in eight liver cancer cell lines, including six HCC cell lines and two combined hepatocholangiocarcinoma (CHC) cell lines. Immunohistochemistry showed the expression of ICAM-1 on the HCC cell surface with honeycomblike appearance in most cases (96.2%). On the other hand, hepatocytes in noncancerous areas did not express ICAM-1, except those hepatocytes in the periportal and intra-acinar areas with inflammation. Immunohistochemical study on cultured cells revealed that four cultured HCC cell lines and one CHC cell line constitutively expressed ICAM-1 on the cell surface and in the cytoplasm. Flow cytometric analysis revealed that immunostain-positive cells expressed surface ICAM-1 with more than a 90% positive cell rate, and their expressions were upregulated by incubation of cells with inflammatory cytokines, such as interferon alfa, interferon gamma, tumor necrosis factor-α, and interleukin 1β. Soluble ICAM-1 was detected in supernatants of cell lines expressing cell surface ICAM-1, in addition to one HCC cell line without surface ICAM-1 expression, and was increased in amounts 2- to 20-fold by inflammatory cytokines. These findings suggest that liver cancer cells in ex vivo may express not only surface but also a soluble form of ICAM-1, differently from normal hepatocytes, and that both expressions are upregulated by inflammatory cytokines. (Hepatology 1995; 22:1708-1713).
The Microscopical Examination of Foods and Drugs. A Practical Introduction to the Methods Adopted in the Microscopical Examination of Foods and Drugs, in the Entire, Crushed and Powdered States.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
High-Dosage Intravenously Administered Methylprednisolone in Renal Transplantation
Authors: John E. Woods
Journal: JAMA (1973)

Large doses of methylprednisolone were used intravenously as the sole steroid agent in 44 transplants in 43 renal allografted patients for the first two to three weeks after operation and for all episodes of rejection. Orally administered steroids were used only at uniformly low dosage. Although significant rejection episodes occurred, they were almost universally reversible when methylprednisolone was administered intravenously in high doses, the exceptions being the hyperacute responses. The use of this drug form was associated with minimal stigmata of hypercorticism and a low incidence of complications, despite transplantation in high-risk patients.
Modern Operative Surgery.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Marriage and Divorce After Childhood and Adolescent Cancer
Authors: Julianne Byrne
Journal: JAMA (1989)

As part of a study of long-term survivors of childhood and adolescent cancer, we interviewed 2170 survivors and 3138 sibling control subjects about their marital histories. In a proportional hazards analysis, both male and female survivors were less likely to be ever married than control subjects (rate ratio [RR] for males, 0.87; 99% confidence interval, 0.76 to 0.99; RR for females, 0.86; 99% confidence interval, 0.76 to 0.97). Survivors of brain and central nervous system tumors accounted for most of the marriage deficit, which was greater in men than in women (RRs, 0.48 and 0.73, respectively). Survivors married at the same average age as control subjects, except for survivors of central nervous system tumors, who married slightly later. The average length of first marriages was shorter in survivors than in control subjects. Men who had survived central nervous system tumors diagnosed before 10 years of age and male survivors of retinoblastoma had higher divorce rates than male control subjects (RRs, 2.9 and 1.9, respectively). In this cohort (which received less intense therapy than given in current practice), altered marriage practices are substantial only among survivors of central nervous system tumors. (<i>JAMA</i>. 1989;262:2693-2699)
Editorial board and contents
Authors: Clint Kelly, Michael Jennions, Natasha Lebas, Simon Lewis, Oliver Phillips, Timothy Baker, S Wright, Paul Del Giorgio, Peter Le, B Williams, Nia Whiteley, John Crawford, Brian Mcgill, Brian Enquist, Evan Weiher, Mark Westoby, Eyal Shochat, Paige Warren, Stanley Faeth, Nancy Mcintyre, Diane Hope, Jason Kaye, Peter Groffman, Nancy Grimm, Lawrence Baker, Richard Pouyat, Anders Pape Møller, Timothy Mousseau, Anna Traveset, David Richardson, Paul Barrett, Emily Rayfield Trendsin, Katrina Lythgoe, Linsey Stapley, Lisa Norman, William Spouge, Manager Moulton
Journal: Trends in Ecology & Evolution (2006)
Poststreptococcal glomerulonephritis.
Authors: M García-Fuentes, M Arias
Journal: BMJ (1979)

Poststreptococcal glomerulonephritisChronic glomerulonephritis is the most common cause of renal failure in patients suitable for dialysis and trans- plantation.' Few of them, however, can remember an episode of acute glomerulonephritis; and how often acute post- streptococcal glomerulonephritis has long-term sequelae (renal failure or raised blood pressure) remains uncertain.In attempting to classify glomerulonephritis pathologists and physicians have struggled to find common ground, and many varieties have been identified and others reclassified.Acute poststreptococcal glomerulonephritis has survived this process to remain a definable and usually easily recog- nisable disease.It has a reasonably consistent clinical picture, a known cause, and-if textbooks are to be believed-a predictable and in most cases a benign natural history.A few patients can be recognised early on to have adverse features on clinical grounds, and in these the probability of a poor prognosis may be supported by examination of a renal biopsy specimen.In 1977 the belief that most patients with poststreptococcal glomerulonephritis have a good prognosis was challenged by Baldwin and his colleagues in New York.2They observed that patients who had shown a complete clinical recovery, with no proteinuria, no abnormality in the urine deposit, and no hypertension, could present later with sclerosed kidneys and renal failure or hypertension-but with no sign of active glomerulonephritis in biopsy specimens.The New York study suggested that after acute poststreptococcal glomerulonephritis less than half of all patients would have normal renal histology and renal function if followed up over several decades despite, in some, a period of clinical normality.Their experience, though more extensive than most other series, may have been distorted by an initial selection of the more severe cases and also by loss from follow-up of over half their patients, perhaps mostly those with milder disease.There is also the possibility (as in most such studies) that either the "seed" or the "soil" was atypical and unusually conducive to a poor long-term prognosis.The New York patients were of mixed ethnic origin-less than half Caucasian, and many came from underprivileged sections of the community.They had acute glomerulonephritis between 1959 and 1972, and the strepto- cocci present at that time may have had a greater potential for causing chronic illness than at other times or in other places.
Neuropathy and Nitrous Oxide Exposure
Authors: John F. Kreul
Journal: JAMA (1981)

<h3>To the Editor.—</h3> Michael A. Nevins, MD (1980;244:2264), recently described two patients who experienced peripheral neuropathy after chronic nitrous oxide abuse. His report adds further emphasis to recent Food and Drug Administration warnings concerning the short-term and long-term hazards of nitrous oxide abuse.<sup>1</sup>Frequently, medical and dental students as well as health professionals who have easy access to the drug are involved with its abuse.<sup>2</sup>However, even among nonabusers, a potential risk is present. As Nevins pointed out, "occupational long-term low-level exposure [has been] implicated" in some dentists with myeloneuropathy. In addition to such case reports, Cohen et al<sup>3</sup>in an extensive survey showed that dentists and chairside assistants who employed nitrous oxide had a 1.8-fold to 4.4-fold increase in nonspecific neurological disease (tingling, numbness, and muscle weakness) as compared with colleagues who were not chronically exposed to subanesthetic levels of nitrous oxide. While such epidemiologic surveys
Is glucuronidation truly preserved in patients with liver disease?
Authors: Anastacio M. Hoyumpa, Steven Schenker
Journal: Hepatology (1991)

The burden of degrading pharmacological agents falls heavily on the liver.It accomplishes this important task with its vast array of enzymes.The principal metabolic reactions involved are oxidation and conjugation.These routes of drug biotransformation may differ from each other in a number of ways as discussed below.areas for the synthetic or conjugative phase of drug metabolism.P-450 (UP to 100-fold) (13).
LECTURES ON GENERAL ETIOLOGY.Delivered at the Chicago Medical College.
Authors: H. GRADLE
Journal: JAMA (1892)

LECTURE IV. One of the conditions determining the occurrence of certain infections is the act of "taking cold." The dread of this event has such a hold on public belief, that it is difficult to sift the truth out of the immense array of alleged instances in which patients attribute diseases to "cold." Chilling of the body is such a common occurrence, and is followed by disease in but so small a proportion of cases, that we can infer a causal relation to the subsequent malady only when we can obtain, with some regularity and precision, the history of cooling of the surface preceding a given form of disease in numerous instances, and within a definite period of time. This is the case in acute nasal catarrh. On the basis of its pathology and clinical history, we must regard acute suppurative rhinitis as an infection, although the virus has not
Karyotype Studies on Human Leukemic Lymphoblasts &lt;italic&gt;In Vitro&lt;/italic&gt; and as Serial Transplants in Neonatal Syrian Hamsters&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;
Authors: Krishan, Awtar, Raychaudhuri, Ratna, Flowers, Arlene
Journal: JNCI Journal of the National Cancer Institute (1969)

Journal Article Karyotype Studies on Human Leukemic Lymphoblasts In Vitro and as Serial Transplants in Neonatal Syrian Hamsters Get access Awtar Krishan, Awtar Krishan The Children's Cancer Research Foundation, and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115 Search for other works by this author on: Oxford Academic PubMed Google Scholar Ratna Raychaudhuri, Ratna Raychaudhuri The Children's Cancer Research Foundation, and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115 Search for other works by this author on: Oxford Academic PubMed Google Scholar Arlene Flowers Arlene Flowers The Children's Cancer Research Foundation, and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 43, Issue 6, December 1969, Pages 1203–1214, https://doi.org/10.1093/jnci/43.6.1203 Published: 01 December 1969 Article history Received: 07 August 1967 Revision received: 03 August 1969 Accepted: 11 August 1969 Published: 01 December 1969