tbuckley/cabot-search huggingface dataset:
Clinical Examination of the Urine and Urinary Diagnosis. A Clinical Guide for the Use of Practitioners and Students of Medicine and Surgery.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Is Hysterectomy a Risk Factor for Vaginal Cancer?
Authors: James M. Herman
Journal: JAMA (1986)

Several recent case series have called attention to a possible association between previous hysterectomy and the subsequent development of vaginal cancer. To study this relationship, we compared 49 patients with vaginal cancer with 49 controls matched for age, race, and prior cervical dysplasia or neoplasia. Patients and controls were alike in terms of exposure to estrogens. Twenty-four patients (49%) had had prior hysterectomies, of which 13 (27%) were for benign disease. Similarly, 24 controls had a history of a hysterectomy. The matched-pairs odds ratio relating prior hysterectomy to vaginal cancer was 1.00 based on these data, with a 95% confidence interval of 0.47 to 2.12. In the subsample of women without a history of cervical disease, a similar odds ratio appeared. Although the study sample size did not permit exclusion of a twofold increase in risk, the statistical power to detect an actual odds ratio of 2.5 is 76%. At this level of statistical power, our data suggest that hysterectomy has a low probability of being a risk factor for vaginal cancer when age and cervical disease are controlled for. In the absence of such a relationship, screening for vaginal cancer does not appear to be necessary for women who have had a hysterectomy for benign disease. (<i>JAMA</i>1986;256:601-603)
Metronidazole and Transient Leukopenia
Authors: Jo Ann T. Taylor
Journal: JAMA (1965)

<h3>To the Editor:—</h3> Lefebvre and Hesseltine (<b>194</b>:15, 1965) reported a 1% incidence of transient leukopenia and neutropenia in 386 patients treated up to 14 days with metronidazole for<i>Trichomonas vaginalis</i>infections. Such findings may be less alarming than implied. While it was not the primary purpose of the writer's study to statistically analyze hematopoietic effects of the agent, over 2,000 complete blood counts and 9 bone-marrow biopsies have been done in 605 treated patients with metabolic, endocrine, or autoimmune disorders. Comparable amounts of the drug were used, but for more prolonged periods than in the above study. Twelve subjects, whose white blood cell counts ( WBCs) and peripheral smears were normal prior to therapy, showed the same transient leukopenia and neutropenia described by Lefebvre and Hesseltine. However, the circulating elements spontaneously returned to normal after the 14th day of treatment, and remained so in every case. At the same time
Recurrence of Infectious Mononucleosis
Authors: P. K. Edmunds
Journal: JAMA (1972)

<h3>To the Editor.—</h3> We are inclined to agree with Dr. Kenneth Rose (221: 195, 1972) of the University of Nebraska Health Service. In 16 years' experience with cases of infectious mononucleosis, and representing thousands of cases, usually with two to three years of follow-up study (since the majority of our cases are in the underclassmen, coming to us from out-of-state), we have not encountered a recurrence. That recurrence might be documented I would not presume to deny, since the word "never" is used very sparingly, if at all, in medicine. But I would suggest that such is, in our experience, probably very rare.
Still Disease in Adults
Authors: Michael S. Fabricant
Journal: JAMA (1973)

Two patients with adult-onset Still disease had a characteristic eruption most prominent during the febrile episodes, splenomegaly, and prolonged fever with temperature elevations to 40.6 C. Extensive investigation excluded other possible causes of fever. One patient partially responded to gold sodium thiomalate therapy. Still disease appears to be distinct from seropositive rheumatoid arthritis.
Triage of Ambulatory Patients
Authors: Stephen L. Adams
Journal: JAMA (1996)

The word triage is derived from the French verb<i>trier</i>, meaning to sort, sift, or cull. One of the original uses was applied to the sorting of beans, such as coffee, by type and size.<sup>1</sup>The first application of the concept in medicine was on the military battlefield, where triage involved the rapid determination of priority for use of limited medical resources. Injured soldiers were sorted as to those who would require immediate treatment (and likely return to battle), those who could wait for treatment, and those for whom treatment would be futile.<sup>2</sup>Today, the triage process has assumed a central role in the initial evaluation and classification of patients seeking emergency treatment and also has become increasingly used in the managed care setting for determining access and granting authorization for acute care. See also p 460. In the emergency department (ED), identification of patients who require treatment
Still `Dark Ages' for neurofibromatosis
Authors: Heather Carswell
Journal: JAMA (1982)

An estimated 80,000 Americans are believed to have neurofibromatosis (NF), which occurs in one of every 3,000 live births. Inherited as an autosomal dominant trait, the progressive disorder shows no discrimination in its sex, racial, or ethnic distribution. Approximately half the cases are new mutations, making NF possibly one of the most common mutations in man. Says geneticist Angela Obringer, PhD, of the neurofibromatosis clinic at Children's Hospital, Philadelphia: "Clinicians must now realize that NF ranks right up there with the more commonly recognized genetic disorders causing congenital anomalies and mental retardation." Although much remains<i>un</i>known about the disorder, one known is the relatively high risk of malignancy. In the pediatric population, for example, NF is considered the most common genetic condition predisposing children to the development of cancer, according to pediatric oncologist Anna T. Meadows, MD, co-director of the Philadelphia clinic. Meadows has done a survey of 5,000
Duodenal inhibition of gastric secretion by osmotic agents in normal subjects and patients with duodenal ulcer
Authors: A. S. Ward, R. A. Wilkins, R. Cockel, C. W. O. Windsor
Journal: Gut (1969)

Gastric secretion in man is inhibited by the presence in the duodenum of hyperosmolar and hypoosmolar solutions. Both acid and pepsin outputs are affected. There is no change in hydrogen, sodium, or potassium ion concentration in the gastric juice. Pepsin concentration, however, is reduced by all inhibitory stimuli. Inhibition is thought to act directly upon parietal and chief cells, and a possible basis for this mechanism is discussed. The response is similar in control subjects and duodenal ulcer patients; there is in particular no evidence of impaired inhibition in the ulcer group. An anomalous feature is the relatively small inhibition of acid output after hypertonic saline in control subjects compared with the duodenal ulcer patients.
Mandatory reporting of infectious diseases by clinicians
Authors: T. L. Chorba
Journal: JAMA (1989)

Reporting of cases of communicable disease is important in the planning and evaluation of disease prevention and control programs, in the assurance of appropriate medical therapy, and in the detection of common-source outbreaks. In the United States, the authority to require notification of cases of disease resides in the respective state legislatures. We examined the laws and regulations of health departments of all US jurisdictions to ascertain diseases and conditions currently required to be reported in each state or territory. We present herein the state reporting requirements for infectious diseases and infectious disease—related conditions. To obtain additional information regarding time frames for reporting, agencies to which reports are required, persons required to report, and specific conditions under which reports are required, the reader is referred to the statutes and health department regulations of the respective states. (<i>JAMA</i>. 1989;262:3018-3026)
Anatomy, Descriptive and Surgical
Journal: JAMA (1901)

This new century edition of "Gray's Anatomy" looks almost like a different book when compared with the older ones. It has been thoroughly revised, and about 60 new illustrations added, replacing some of the old wood-cuts. The newer processes of picture-making have enabled the publishers to produce differences in shading to represent curves, cavities and portions more remote, which art is an excellent aid in descriptive anatomy.
THE HORMONAL CONTROL OF LACTATION
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Use of Anabolic Steroids by Athletes
Authors: Dwight A. Johnson
Journal: JAMA (1984)

<h3>To the Editor.—</h3> In the Aug 1 issue of<i>Sports Illustrated</i>(pp 62-77), there was a good article on the apparent widespread use of anabolic steroids by participants in almost every American sport, but especially among weight lifters. Although I was aware that some athletes did this, I did not know that the practice was nearly so commonplace as it apparently is. Since I read that article, I have found that two of my patients were using the drugs and would not have told me about it if I had not asked about the practice specifically. Both told me that they really did not consider themselves to be taking a drug, at least not one that I would be concerned about. I believe the medical community needs to be more aware of this problem, and some effort should be put forth to control it. Although these are prescription drugs, it
Incidence of Lymphatic Leukemia and Methylcholanthrene-Induced Cancer in Laboratory Mice Subjected to Stress&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;
Authors: N. Kaliss, J. L. Fuller
Journal: JNCI Journal of the National Cancer Institute (1968)

The incidence and age at appearance of spontaneous leukemias and 3-methylcholanthrene-induced cancers were determined in mice subjected to various stressors. Leukemia incidence was followed in AKR mice subjected to electroshock or to crowded housing and in (AKR × DBA/2)F1 hybrids experiencing audiogenic seizures. The incidence of methylcholanthrene-induced tumors was followed in C57BL/6J mice subjected to electroshock and in (C57BL/6J × DBA/2)F1 hybrids experiencing audiogenic seizures. Physiological effects of the stressors were assayed in terms of body weight gain, rectal temperature, spleen weight, adrenal weight, and behavioral activity. Though the stressors affected weight gain, rectal temperature, and activity, differences between control and experimental groups in cancer incidence or time of appearance of cancer were not significant.
Функціональний стан шлунка та імунологічна резистентність у дітей перших місяців життя
Authors: S.M. Dmytriieva
Journal: GASTROENTEROLOGY (2014)

У статті подано результати дослідження функціонального стану шлунка, показників неспецифічної резистентності та мікробної колонізації кишечника в новонароджених та дітей перших місяців життя. Встановлено, що в перші місяці життя віковою особливістю є слабокислий інтрагастральний рН (4,6 ± 0,5). Цикл міжтравної моторики визначається режимом годування малюків. При повній евакуації шлункового вмісту через 2,5–3,0 години після годування дитини моторика шлункових скорочень становить (5,4 ± 0,4), внутрішньошлунковий тиск — (13,1 ± 1,3) мм рт.ст. Показано, що функціональне становлення шлунково-кишкового тракту здійснюється у взаємозв’язку з процесами формування місцевих факторів неспецифічного захисту травної системи та фізіологічної контамінації кишечника.
British Practitioners in Italy
Authors: S. Tidey
Journal: BMJ (1898)

Objective: To analyse the cost effectiveness of a national programme to screen blood donors for infection with the human T cell leukaemia/lymphoma virus.Design: Three models for calculating the costs and benefits of screening were developed.The first model analysed the cost of continuously testing all donations; the second analysed the cost of initially testing new blood donors and then retesting them after five years; the third analysed the cost of testing donors only at the time of their first donation.Patients who had received blood components from donors confirmed to be infected with the virus were offered testing.Setting: Sweden.Main outcome measures: Prevalence of infection with the virus among blood donors, the risk of transmission of the virus, screening costs, and the outcome of infection.Results: 648 497 donations were tested for the virus; 1625 samples tested positive by enzyme linked immunosorbent assay.6 were confirmed positive by western blotting.The prevalence of infection with the virus was 2/100 000 donors.35 patients who had received blood infected with the virus were tested; 3 were positive.The cost of testing every donation was calculated to be $3.02m (£1.88m); this is 18 times higher than the cost of testing new donors only, and only 1 additional positive donor would be discovered in 7 years.Regardless of the model used, screening was estimated to prevent only 1 death every 200 years at a minimum cost of $36m (£22.5m).
Editorial Board and Contents
Authors: Caryn Navarro, Danielle Loughlin, Paige Shaklee, Yvonne Philippo, Ria Otten, Patrick Scheffmann, Erik Andersen, Kirsten Bomblies, Martha Bulyk, Ling Chen, Andy Clark, Sue Clark, Susan Gasser, David Goldstein, Leonard Guarente, Yoshihide Hayashizaki, Steven Henikoff, Chris Hittinger, Laurence Hurst, Aldons Lusis, Jake Lusis, Angela Nieto, Chris Ponting, Claudio Scazzocchio, Bob Schmitz, Nicole Soranzo, Trisha Wittkopp, Joanna Wysocka
Journal: Trends in Genetics (2018)
Systemic Vasculitis With Coexistent Large and Small Vessel Involvement
Authors: Richard D. deShazo
Journal: JAMA (1977)

A patient with systemic vasculitis had the palpable purpuric lower extremity lesions of leukocytoclastic vasculitis and the renal aneurysms of polyarteritis nodosa, features thought to clearly separate these two syndromes. Questions are raised pertinent to the classification, diagnosis, treatment, and prognosis of systemic vasculitis. (<i>JAMA</i>238:1940-1942, 1977)
Chemical Carcinogenesis.
Journal: Annals of Internal Medicine (1963)

Previous studies in animals and humans have shown that selenium compounds can prevent cancer development.In this work we studied the tumor preventive effect of selenium supplementation, administrated as selenite, in the initiation, promotion and progression phases in a synchronized rat model for chemically induced hepatocarcinogenesis, the resistant hepatocyte model.Selenite in supra-nutritional but subtoxic doses (1 and 5 p.p.m.) was administrated to the animals through the drinking water.Such supplementation during the initiation phase did not have a tumor preventive effect.However, selenite treatment during the promotion phase decreased the volume fraction of pre-neoplastic liver nodules from 38% in control animals to 25 (1 p.p.m.) and 14% (5 p.p.m.) in the selenite-supplemented groups.In addition the cell proliferation within the nodules decreased from 42% in the control to 22 (1 p.p.m.) and 17% (5 p.p.m.).Immunohistochemical staining for the selenoenzyme thioredoxin reductase 1 revealed an increased expression of the enzyme in liver nodules compared with the surrounding tissue.The activity was reduced to 50% in liver homogenates from selenium-treated animals but the activity of the selenoenzyme glutathione peroxidase was essentially unaltered.Selenite treatment (5 p.p.m.) during the progression phase resulted in a significantly lower volume fraction of liver tumors (14 compared with 26%) along with a decrease in cell proliferation within the tumors (34 compared with 63%).Taken together our data indicate that the carcinogenetic process may be prevented by selenium supplementation both during the promotion and the progression phase.
Greater IUD perforation risk, lactation linked
Authors: Beverly Merz
Journal: JAMA (1983)

Women who have an intrauterine device (IUD) inserted during lactation run a tenfold greater risk of uterine perforation than do nonlactating women, according to a nine-center Women's Health Study. The study, organized to examine various complications of IUD use, was supported by the National Institute of Child Health and Human Development, Bethesda, Md. Results of this phase of the investigation were generated from a study group of 32 women hospitalized for uterine perforation necessitating transperitoneal IUD removal and a control group of 497 women, matched by age and race, who had worn IUDs uneventfully for a mean period of 15 months (<i>Obstet Gynecol</i>1983;61:31-36). Thirty-one women (97%) in the study group had given birth, compared to 337 (68% ) in the control group. Because the correlation between parity and uterine perforation was so strong, the investigators restricted further analysis to women in both groups who had borne children. They then determined
Generalized pruritus in anorexia nervosa
Authors: S. TANIGUCHI, N. YAMAMOTO, T. KONO, T. HAMADA
Journal: British Journal of Dermatology (1996)

We report a 19-year-old woman with the associated disorders of generalized pruritus, hypertrichosis and anorexia nervosa, all of which had been present for approximately 4 months. Psychotherapy induced both weight gain and resolution of the pruritus. We propose that anorexia-associated pruritus be considered one of the important cutaneous signs in anorexia nervosa.
Current Status of Predictive Animal Models for Drug Photoallergy and Their Correlation With Drug Photoallergy in Humans&lt;xref ref-type="fn" rid="FN1"&gt;1&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;
Authors: Harber, Leonard C., Armstrong, Robert B., Ichikawa, Hideyuki
Journal: JNCI Journal of the National Cancer Institute (1982)

Journal Article Current Status of Predictive Animal Models for Drug Photoallergy and Their Correlation With Drug Photoallergy in Humans Get access Leonard C. Harber, M.D., Leonard C. Harber, M.D. 3Department of Dermatology, College of Physicians and Surgeons, Columbia University, 630 West 168th St., New York, N.Y. 10032. Search for other works by this author on: Oxford Academic PubMed Google Scholar Robert B. Armstrong, M.D., Robert B. Armstrong, M.D. 3Department of Dermatology, College of Physicians and Surgeons, Columbia University, 630 West 168th St., New York, N.Y. 10032. Search for other works by this author on: Oxford Academic PubMed Google Scholar Hideyuki Ichikawa Hideyuki Ichikawa 4Laboratory of Dermatology and Toxicology, Shiseido Laboratories, Yokohama, Japan. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 69, Issue 1, July 1982, Pages 237–244, https://doi.org/10.1093/jnci/69.1.237 Published: 01 July 1982
Acceptability of Day Care Surgery
Authors: A Senapati, A E Young
Journal: Journal of the Royal Society of Medicine (1989)

Although day case surgery is recommended, its widespread feasibility in an urban environment is unclear. We studied 100 consecutive unselected patients admitted for surgical procedures considered to be suitable for day case surgery. Their age, fitness and social details were recorded and they were asked both before surgery and after discharge by a postal questionnaire, whether they would have preferred treatment as an outpatient. There were 47 men and 53 women with a mean age of 42.5 years. Ninety-six were considered to be medically fit for day case surgery but 10 patients lived alone, seven had no suitable companion, 22 had too many stairs to climb, 13 lived too far from the hospital and two could not provide a lift home. Thus 58 of the patients were unsuitable for day case surgery. Seventy-eight of the patients replied to the postal questionnaire. Before the operation 51 patients preferred the idea of day care but only 14 felt the same way afterwards. The single postoperative complication was one case of acute retention after a hernia repair. In our experience, over half the patients initially deemed suitable for day case surgery would be unsuitable.
The Surgical Assistant. A Manual for Students, Practitioners, Hospital Internes and Nurses.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal