Genes and HIV Progression
Journal: Annals of Internal Medicine (2001)

Summaries for Patients6 November 2001Genes and HIV ProgressionSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-9-200111060-00004 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?There are more than 30,000 genes in a human body cell. Each gene in a pair is located in the same place on a pair of similar chromosomes. Genes have alternate forms that are known as alleles. A gene may have a few or several hundred different alleles. Different alleles account for inherited differences between individuals, such as varying eye color. Alleles may also play a part in the cause and progression of diseases. For example, individuals differ in the likelihood of developing AIDS after becoming infected with ... Author, Article, and Disclosure InformationThe summary below is from the full report titled “Effects of CCR5-Δ32, CCR2-64I, and SDF-1 3′A Alleles on HIV-1 Disease Progression: An International Meta-Analysis of Individual-Patient Data.” It is in the 6 November 2001 issue of Annals of Internal Medicine (volume 135, pages 782-795). The authors are JPA Ioannidis, PS Rosenberg, JJ Goedert, LJ Ashton, TL Benfield, SP Buchbinder, RA Coutinho, J Eugen-Olsen, T Gallart, TL Katzenstein, LG Kostrikis, H Kuipers, LG Louie, SA Mallal, JB Margolick, OP Martinez, L Meyer, NL Michael, E Operskalski, G Pantaleo, GP Rizzardi, H Schuitemaker, HW Sheppard, GJ Stewart, ID Theodorou, H Ullum, E Vicenzi, D Vlahov, D Wilkinson, C Workman, J-F Zagury, and TR O'Brien, for the International Meta-Analysis of HIV Host Genetics.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffects of CCR5-Δ 32, CCR2-64I, and SDF-1 3′A Alleles on HIV-1 Disease Progression: An International Meta-Analysis of Individual-Patient Data John P.A. Ioannidis , Philip S. Rosenberg , James J. Goedert , Lesley J. Ashton , Thomas L. Benfield , Susan P. Buchbinder , Roel A. Coutinho , Jesper Eugen-Olsen , Teresa Gallart , Terese L. Katzenstein , Leondios G. Kostrikis , Harmjan Kuipers , Leslie G. Louie , Simon A. Mallal , Joseph B. Margolick , Olga P. Martinez , Laurence Meyer , Nelson L. Michael , Eva Operskalski , Giusseppe Pantaleo , G. Paolo Rizzardi , Hanneke Schuitemaker , Haynes W. Sheppard , Graeme J. Stewart , Ioannis D. Theodorou , Henrik Ullum , Elisa Vicenzi , David Vlahov , David Wilkinson , Cassy Workman , Jean-Francois Zagury , and Thomas R. O'Brien , for the International Meta-Analysis of HIV Host Genetics Metrics 6 November 2001Volume 135, Issue 9Page: I-52KeywordsAIDSAllelesCaucasian peopleGenetic diseasesGenetic testingGeneticsHIVHIV infectionsHIV-1Infectious diseases ePublished: 6 November 2001 Issue Published: 6 November 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...