Oophorectomy at the Time of Hysterectomy: The Debate Continues
Authors: Elizabeth Casiano Evans, Deslyn T.G. Hobson
Journal: Annals of Internal Medicine (2023)

EditorialsMay 2023Oophorectomy at the Time of Hysterectomy: The Debate ContinuesElizabeth Casiano Evans, MD, Deslyn T.G. Hobson, MDElizabeth Casiano Evans, MDUniversity of Texas Health Science Center San Antonio, San Antonio, TexasSearch for more papers by this author, Deslyn T.G. Hobson, MDWayne State University School of Medicine, Detroit, MichiganSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M23-0756 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Hysterectomy is a common surgical procedure in women. According to a 2018 National Health Interview Survey from the United States, 31.8% of women aged 50 years or older have had a hysterectomy (1). The question of removing ovaries at the time of benign hysterectomy to prevent ovarian cancer in low-risk women has been widely debated. Incidence rates of unilateral and bilateral oophorectomy have varied over time, partly because of this debate. In a longitudinal study (2), rates varied over a 69-year period and more recent trends were affected by evidence against the practice of oophorectomy starting in 2005 to 2006. According ...References1. QuickStats: percentage of women aged ≥50 years who have had a hysterectomy, by race/ethnicity and year - National Health Interview Survey, United States, 2008 and 2018. MMWR Morb Mortal Wkly Rep. 2019;68:935. [PMID: 31622285] doi:10.15585/mmwr.mm6841a3 CrossrefMedlineGoogle Scholar2. Erickson Z, Rocca WA, Smith CY, et al. Time trends in unilateral and bilateral oophorectomy in a geographically defined American population. Obstet Gynecol. 2022;139:724-734. [PMID: 35576330] doi:10.1097/AOG.0000000000004728 CrossrefMedlineGoogle Scholar3. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin. 2018;68:7-30. [PMID: 29313949] doi:10.3322/caac.21442 CrossrefMedlineGoogle Scholar4. Finch AP, Lubinski J, Møller P, et al. Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation. J Clin Oncol. 2014;32:1547-53. [PMID: 24567435] doi:10.1200/JCO.2013.53.2820 CrossrefMedlineGoogle Scholar5. Xiao YL, Wang K, Liu Q, et al. Risk reduction and survival benefit of risk-reducing salpingo-oophorectomy in hereditary breast cancer: meta-analysis and systematic review. Clin Breast Cancer. 2019;19:e48-e65. [PMID: 30470623] doi:10.1016/j.clbc.2018.09.011 CrossrefMedlineGoogle Scholar6. Erickson BK, Conner MG, Landen CN. The role of the fallopian tube in the origin of ovarian cancer. Am J Obstet Gynecol. 2013;209:409-14. [PMID: 23583217] doi:10.1016/j.ajog.2013.04.019 CrossrefMedlineGoogle Scholar7. Evans EC, Matteson KA, Orejuela FJ, et al; Society of Gynecologic Surgeons Systematic Review Group. Salpingo-oophorectomy at the time of benign hysterectomy: a systematic review. Obstet Gynecol. 2016;128:476-85. [PMID: 27500347] doi:10.1097/AOG.0000000000001592 CrossrefMedlineGoogle Scholar8. Rush SK, Ma X, Newton MA, et al. A revised Markov model evaluating oophorectomy at the time of hysterectomy for benign indication: age 65 years revisited. Obstet Gynecol. 2022;139:735-744. [PMID: 35576331] doi:10.1097/AOG.0000000000004732 CrossrefMedlineGoogle Scholar9. Gottschau M, Rosthøj S, Settnes A, et al. Long-term health consequences after ovarian removal at benign hysterectomy. A nationwide cohort study. Ann Intern Med. 2023;176:596-604. doi:10.7326/M22-1628 Google Scholar Author, Article, and Disclosure InformationAuthors: Elizabeth Casiano Evans, MD; Deslyn T.G. Hobson, MDAffiliations: University of Texas Health Science Center San Antonio, San Antonio, TexasWayne State University School of Medicine, Detroit, MichiganDisclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M23-0756.Corresponding Author: Elizabeth Casiano Evans, MD, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229; e-mail, casianoe@uthscsa.edu.This article was published at Annals.org on 18 April 2023. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoLong-Term Health Consequences After Ovarian Removal at Benign Hysterectomy Mathilde Gottschau , Susanne Rosthøj , Annette Settnes , Gitte Lerche Aalborg , Jakob Hansen Viuff , Christian Munk , Allan Jensen , Susanne K. Kjær , and Lene Mellemkjær Metrics May 2023Volume 176, Issue 5Page: 723-724KeywordsBreast cancerCancer preventionCardiovascular diseasesHysterectomyMenopauseOophorectomyOvarian cancer ePublished: 18 April 2023 Issue Published: May 2023 Copyright & PermissionsCopyright © 2023 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...