tbuckley/cabot-search huggingface dataset:
Investigation results in disciplinary action against researchers, retraction of articles
Authors: J. W. Zylke
Journal: JAMA (1989)

QUESTIONABLE ETHICAL practices seem to infect many sectors of society, with the current antidote being to get rid of the offender. Congress sweeps out its own speaker of the house. Wall Street executives are prosecuted. And the scientific community investigates its researchers. In the latter category, inquiry into a controversial case has just been completed by the National Institute of Mental Health (NIMH), Rockville, Md, resulting in disciplinary action against two researchers and the retraction of a number of papers, two in American Medical Association journals. The saga began in the summer of 1986, when Stanford (Calif) University received a formal complaint about possible fiscal and professional misconduct on the part of the director of its Mental Health Clinical Research Center (MHCRC), Philip Berger, MD. Berger was also the principal investigator for the NIMH grant that funded the center. A university investigation found not only that money had been improperly
Cancer Mortality After Nonmelanoma Skin Cancer
Authors: John S. Spratt
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Impaired Glucose Tolerance of Pregnancy Is a Heterogeneous Metabolic Disorder as Defined by the Glycemic Response to the Oral Glucose Tolerance Test
Authors: R. Retnakaran
Journal: Diabetes Care (2006)

OBJECTIVE—Gestational diabetes mellitus (GDM), defined by two abnormal glucose values on a 3-h oral glucose tolerance test (OGTT), is associated with insulin resistance and a low serum concentration of adiponectin. The metabolic implications of impaired glucose tolerance (IGT) of pregnancy (i.e., a single abnormal value on an OGTT), however, are not well established. We sought to evaluate the metabolic phenotype of pregnant women with IGT in relation to the timing of their isolated hyperglycemia.
LETTER FROM LONDON.
Authors: None G. O. M.
Journal: JAMA (1889)

(FROM OUR OWN CORRESPONDENT.) The Notification of Infectious Diseases Act—Dr. Jules Simon and the Treatment of Diphtheria— The Pasteur Institute Fund—Hydrochlorate of Pilocarpine in Hystero-Epileptic Attacks—Report of the Royal Commission on Vaccination—Miscellaneous Items. The Notification of Infectious Diseases Act has now come into operation, compulsorily as regards the metropolis and permissively as regards provincial authorities. Under the provisions of the Act notification must be given, in the case of certain infectious maladies occurring, both by the head of the household (or in his default by various other persons who are enumerated, including finally the occupier of the building), and also by the medical practitioner attending the patient. As the doctor is under a legal compulsion to do his duty in this respect he need not fear that he will give offense to a foolish employer by disclosing family secrets, and moreover, his diligence will be sharpened by the receipt of
PWE-050 A protocol to avoid corticosteroid exposure prior to crohn’s disease requiring luminal surgery
Authors: KV Patel, EL Johnston, SC Fong, I Nasr, C Amadi, E Westcott, A Williams, A Darakhshan, JM Dunn, S Anderson, PM Irving, JD Sanderson
Journal: Gut (2015)

<h3>Introduction</h3> Corticosteroids (CS) are prescribed to control inflammatory and obstructive symptoms in Crohn’s disease (CD). Preoperative CS are associated with higher risk of all complications post-operatively including sepsis, anastomotic breakdown and venous thromboembolic disease.High doses of CS also preclude a primary anastomosis. In our institution, we have implemented a protocol to prevent CS administration or permit a rapid wean in patients requiring ileal/ileocaecal resection, maximising the use of exclusive enteral nutrition (EEN) or parenteral nutrition (PN). This study aimed to determine the achievability of CS avoidance in this setting. <h3>Method</h3> In patients selected for ileal/ileocaecal resection, EEN (with either Modulen IBD Nestle or Fortisip Nutricia, as tolerated) was prescribed to a target dose of 30 kcal/kg. Acute sepsis was controlled with intravenous and/or oral antibiotics. If EEN was not tolerated because of obstructive symptoms, PN was instituted or surgery expedited. Patients were not offered this protocol if they had minimal symptoms, adequate nutritional status and no CS exposure. <h3>Results</h3> In total, 39 patients with CD had IC resection over a period of 20 months from January 2013. 9 of these underwent urgent surgery due to symptom severity (severe obstruction or suspected cancer where delay not possible [4 of 9 on CS (45%)]. 8 patients with stable symptoms secondary to fibrotic stricture (4 on biologic, 4 on immunomodulator), adequate nutritional status and CS free were not suitable for the protocol. 22 patients with acute symptoms were therefore included. All had penetrating and/or stricturing disease. 8 patients were receiving CS of whom 7 (88%) successfully weaned off CS for greater than 4 weeks using EEN. 1 did not tolerate EEN and proceeded to surgery on CS. A further 11 of 22 patients successfully treated via protocol to avoid CS (EEN n = 7, PN n = 4) 3 patients did not tolerate/declined EEN/PN and proceeded to expedited surgery. Hence, in all patients suitable for the protocol, CS were successfully avoided (14/14 patients, 100%) and wean &gt;4 weeks successful in majority (7/8 patients, 87.5%). CS exposure was successfully avoided in 21 patients via protocol (95.5%). <h3>Conclusion</h3> Aggressive use of EEN or PN provides an effective approach to avoid CS exposure, optimise nutrition and control acute symptoms in patients selected for IC resection. The implementation of the protocol requires close liaison between gastroenterologists, colorectal surgeons and dieticians. The protocol does not delay emergency surgery. <h3>Disclosure of interest</h3> None Declared.
LINNÆUS AS A PHYSICIAN.
Authors: LUDVIG HEKTOEN
Journal: JAMA (1902)

<h3>INTRODUCTION.</h3> Among physician-scientists who achieved their greatest renown in some department of learning other than medicine Carl von Linné, better known as Carolus Linnæus, must be placed in the front rank. This great naturalist made for himself a permanent name in medicine also, but the extent and significance of his work and interest in medicine seem to have been more or less overshadowed by the fundamental importance of his work in natural science, especially botany. The principal sources of the information in this article have been Richard Pulteney's excellent work on the writings of Linnæus, † in which the medical writings also are fully considered, and Hjelt's special work concerning Linnæus as a physician, ‡ based upon personal study of the writings and correspondence of Linnæus and of the records in the archives of the University of Upsala. Both these books appear to give altogether thorough and sympathetic reviews of
CASE OF SUSPECTED RABIES WITH ISOLATION OF BACILLUS DIPHTHERIA FROM THE CENTRAL NERVOUS SYSTEM.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The usefulness of preoperative laboratory screening
Authors: E. B. Kaplan
Journal: JAMA (1985)

We assessed the usefulness of routine laboratory screening of preoperative patients. Computer-readable laboratory, demographic, and discharge diagnostic data were assembled for 2,000 patients undergoing elective surgery over a four-month period, and randomly selected samples of patients were studied. Several tests ordered by protocol and performed by the laboratory at the time of admission were examined in these samples, including complete blood cell count, differential cell count, prothrombin time, partial thromboplastin time, platelet count, six-factor automated multiple analysis, and glucose level. Sixty percent of these routinely ordered tests would not have been performed if testing had only been done for recognizable indications, and only 0.22% of these revealed abnormalities that might influence perioperative management. Chart review indicated that these few abnormalities were not acted on nor did they have adverse surgical or anesthetic consequences. In the absence of specific indications, routine preoperative laboratory tests contribute little to patient care and could reasonably be eliminated. (<i>JAMA</i>1985;253:3576-3581)
Abstract P215: Trends in Hemorrhagic Stroke in Japan, from 1986 to 2010: Circulatory Risk in Communities Study (CIRCS).
Authors: Eri Eguchi, Tetsuya Ohira, Hironori Imano, Akihiko Kitamura, Masahiko Kitamura, Takeo Okada, Kazumasa Yamagishi, Tomoko Sankai, Mitsumasa Umesawa, Renzhe Cui, Minako Maruyama, Takeshi Tanigawa, Yoshinori Ishikawa, Hiroyasu Iso
Journal: Circulation (2013)

Background: The incidence of hemorrhagic stroke has substantially decreased nearly to a quarter over years from 1960s to 1980s in Japan. However, there is little evidence on the trends after 1980, or whether subtypes of hemorrhagic stroke have decreased. We examined trends in the incidence of hemorrhagic stroke and its subtypes. Hypothesis: Hemorrhagic stroke have decreased after 1980s. For intraparenchymal hemorrhage (IPH), lobar and cerebellar intraparenchymal hemorrhage has not decreased. Methods: All residents aged 30 to 84 years in two communities (Akita and Osaka, census population: 18,998 in 2000) in Japan was surveyed. The incidence of IPH and subarachnoid hemorrhage (SAH) from 1986 to 2010 was ascertained by systematic surveillance of hospital records and confirmed by physicians with CT or MRI images. The implementation rate of CT or MRI has not changed materially over years (78.9~97.4%). IPH was further categorized to lobar and cerebellar IPH, and deep IPH (thalamus, basal ganglia or brainstem). The respective age-adjusted incidence rates per 100,000 person-years were calculated by each 5 years of time periods: 1986-1990, 1991-1995, 1996-2000, 2001-2005, and 2006-2010. Results: Age-adjusted incidence of SAH has decreased in 1996-2000 but increased after 2000. Respective age-adjusted incidence rates (per 100,000 person-years) of SAH for 5 time periods were 46.2, 46.5, 14.5, 23.0, and 23.7 (p for trend=0.23). Age-adjusted incidence of all IPH has decreased from 1986-1990 to 2006-2010. Respective incidence rates of IPH were 56.8, 53.7, 48.7, 29.0, and 26.5 (p for trend=0.01). For the subtypes of IPH, incidence of lobar and cerebellar IPH has not decreased from 1986-1990 to 2006-2010, while it have decreased for deep IPH. Respective incidence rates for lobar and cerebellar IPH were 13.1, 7.6, 16.6, 10.9, and 10.3 (p for trend=0.85) and those of deep IPH were 52.0, 53.1, 49.8, 40.8, and 29.5 (p for trend=0.03). Conclusion: The age-adjusted incidence of IPH after 1980s has decreased over years, although such trend was not clear for SAH. Among IPH, the incidence of lobar and cerebellar IPH has not decreased, while the incidence of deep IPH has decreased.
Mainstreaming genetic counselling for genetic testing of BRCA1 and BRCA2 in ovarian cancer patients in Malaysia (MaGiC study)
Authors: S.Y.Y. Yoon, N.S. Ahmad Bashah, S.W. Wong, S. Mariapun, H. Padmanabhan, T. Hassan, J. Lim, S.Y. Lau, N. Rahman, M.K. Thong, G.S. Ch'Ng, S.H. Teo, E. Bleiker, Y.L. Woo
Journal: Annals of Oncology (2018)
THE FAILURE OF THE ERYSIPELAS TOXINS.
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A DIETARY QUACK DISCUSSES DYSENTERY
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MORE TO COME
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Paul Ehrlich-Ludwig Darmstaedter Prize
Journal: JNCI Journal of the National Cancer Institute (1977)

Paul Ehrlich-Ludwig Darmstaedter Prize Get access JNCI: Journal of the National Cancer Institute, Volume 59, Issue 2, August 1977, Page 544, https://doi.org/10.1093/jnci/59.2.544 Published: 01 August 1977
Undergraduate Medical Education
Authors: Anne E. Crowley
Journal: JAMA (1983)

<h3>MEDICAL SCHOOLS</h3><h3>Accreditation</h3> The official accrediting body for educational programs leading to the MD degree is the Liaison Committee on Medical Education (LCME), which is listed for this purpose by the US Secretary of Education and recognized by the Council on Postsecondary Accreditation. (For membership in the LCME, see Appendix I). The criteria by which the LCME accredits such programs in the United States, and in Canada in cooperation with the Committee for the Accreditation of Canadian Medical Schools (CACMS), are published in two separate but related documents: "Functions and Structure of a Medical School" and "Special Criteria for Programs in the Basic Medical Sciences." Copies of these documents are available from the LCME Office, 535 N Dearborn St, Chicago, IL 60610, or 1 Dupont Circle NW, Washington, DC 20036. <h3>Accredited Programs in Medical Education</h3> As of Sept 1, 1983, there were 124 US programs and 16 Canadian programs fully
Endocrine Control of the Thymus and Other Lymphoid Organs
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
International Journal of Epidemiology
Authors: F. J. Ingelfinger
Journal: New England Journal of Medicine (1973)

Background Several countries have reported an increase in life expectancy at advanced ages.This paper analyses recent changes in life expectancy at age 60 and 85 in The Netherlands, a low mortality country with reliable mortality data. MethodsWe used data on the population and the number of deaths by age, sex and underlying cause of death for 1970-1994.Life expectancy at age 60 and 85 was estimated using standard life-table techniques.The contribution of different ages and causes of death to the change in life expectancy during the 1970s (1970/74-1980/84) and the 1980s (1980/84-1990/94) were estimated with a decomposition technique developed by Arriaga. ResultsLife expectancy at age 60 increased in the 1970s and 1980s, whereas life expectancy at age 85 decreased (men) and stagnated (women) in the 1980s, and has decreased in both sexes since 1985/89.The decomposition by age showed that constant mortality rates in women aged 85-89, and increasing mortality rates at ages 85+ (men) and 90+ (women) have caused this lack of increase in life expectancy.The decomposition by cause of death showed that smaller mortality reductions from other cardiovascular and cerebrovascular diseases, which contributed most to the increase in life expectancy at age 85 in the 1970s, and mortality increases from, amongst others, chronic obstructive pulmonary disease (COPD), mental disorders and diabetes mellitus produced the decrease (men) and plateau (women) in life expectancy at age 85.Conclusions Life expectancy at advanced ages stopped increasing during the 1980s in The Netherlands due to mortality increases at ages 85+ (men) and 90+ (women).Cause-specific trends suggest that, in addition to (past) smoking behaviour in men, changes in the distribution of morbidity and frailty in the population might have contributed to this stagnation.
Myasthenia Gravis
Authors: Henry R. Viets
Journal: New England Journal of Medicine (1954)

TreatmentMyasthenic CrisesRandt50 summarizes the treatment of myasthenia gravis, particularly the handling of patients with myasthenic crises. This he describes as an inability to maintain pulmonary ventilation in spite of increasingly large doses of neostigmine, owing to weakness of the respiratory muscles, obstruction of the airway from weakness of the laryngeal or pharyngeal musculature or atelectasis and pneumonia from inability to expel secretions. States of this type may be precipitated or contributed to by overdosage with neostigmine, which is known to have a curarizing effect, with directly opposite results from those desired to maintain life. Randt believes that patients . . .
LEMON JUICE AND TYPHOID FEVER BACILLI.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal