tbuckley/cabot-search huggingface dataset:
THE SIGNIFICANCE OF GRADE, RANK AND TITLE IN THEIR NAVAL MEDICAL RELATIONS.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Another viewpoint regarding periodic checkups
Authors: P. Gunby
Journal: JAMA (1987)

ACKNOWLEDGING "that the question of frequency of periodic health examinations and medical testing is controversial," the Dallas-based American Heart Association (AHA) is recommending that medical checkups for all "apparently healthy" adults begin at age 20 years, be repeated at least every five years until age 60 and every 2 1/2 years thereafter until age 75, and be performed annually after the mid-70s. These and other recommendations are in a report titled "Cardiovascular and Risk Factor Evaluation of Healthy American Adults," approved by the association's Steering Committee (the primary science policy—making body), and published in the current issue of the AHA's journal (<i>Circulation</i>1987;75: 1340A-1362A). The position statement was written by a group appointed by the Steering Committee and headed by Scott Grundy, MD, PhD, director, Center for Human Nutrition, University of Texas Health Science Center, Dallas. It concedes that some "maintain that routine screening of the population is expensive and
Thyroid Storm
Authors: Isadore N. Rosenberg
Journal: New England Journal of Medicine (1970)

Thyroid storm, or thyrotoxic crisis, generally defined as a syndrome in which life-threatening augmentation of the manifestations of hyperthyroidism occurs in association with fever, substantial tachycardia and disturbed function of the central nervous system, is a grave medical emergency. The decline in surgical treatment of diffuse toxic goiter and improved preoperative preparation with antithyroid drugs of patients still subjected to subtotal thyroidectomy have not only diminished the frequency of storm but also resulted in its occurring more often in a medical than in a surgical setting. In the past decade, improvements in the therapy of this complication and perhaps some . . .
The Senses of Taste and Smell
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Massachusetts Department of Public Health
Authors: John C. Ayres
Journal: New England Journal of Medicine (1951)

Traditional popular attitudes in regard to alcoholism emphasize primarily the act and frequency of drinking and the reactions to the quantity consumed. Rarely is there any consideration of why an individual may take to alcohol and lose control over its use. Apparently tradition has settled this point in the minds of many by the implication that alcoholism is a condition brought about by lack or perversion of will power, by dementia or by some hereditary taint. It is true that some who appear to be alcoholics are psychotic to some degree or possess a serious character disorder. However, the majority, . . .
Escaping anesthetic gases may affect neurophysiological functions
Authors: J. Elliott
Journal: JAMA (1978)

Potentially serious neurophysiological deficits may occur after on-the-job exposure to fugitive anesthetic gas emissions, according to Lt Comdr Richard A. Ilka, MC, USN, chief of environmental epidemiology at the Navy Environmental Health Center in Cincinnati. "In 100% of the samples we took at the University of Cincinnati Hospital, the level of anesthetic gases in the operating rooms exceeded the maximum level set by the National Institute of Occupational Safety and Health (NIOSH)," Ilka said. A NIOSH criteria document on anesthetic gases has set 25 ppm as the maximum level of fugitive emissions in operating rooms. In testing for nitrous oxide, the Cincinnati researchers found average levels of 400 ppm. "Our studies have shown that even at 50 ppm there can be a measurable decrement in the ability to pick up serious changes in stimuli," Ilka said. "For example, the anesthesiologist must often listen to heart tones while at the same
BIOCHEMICAL DIAGNOSIS OF NEUROBLASTOMA
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE PHYSIOLOGY OF SLEEP.
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PTU-035 Immunologic responses to hookworm infection in Crohn's disease
Authors: L Meran, D Blount, D Hooi, B Alan, V Subramanian, D Pritchard, C J Hawkey, P Fortun
Journal: Gut (2010)

<h3>Introduction</h3> Helminths such as hookworms survive by modulating host immune responses as a strategy to escape the host9s defence mechanisms.1 Hookworm infection is demonstrated by a polarised Th2 response, releasing characteristic cytokines (IL-4, IL-5, IL-10, IL-13). Conversely, Crohn9s disease is characterised by a Th1 response, releasing pro-inflammatory cytokines (TNF, IFN, IL-2)2. The reciprocal inhibition of cytokine products between distinct T helper cell responses, has led to studies of hookworms as adjuncts to immunosuppressants in Crohn9s disease.2 The Nottingham Digestive Diseases Centre recently completed a placebo-controlled trial on the effect of hookworms on disease activity in Crohn9s disease, providing an opportunity to study changes in T cell populations. <h3>Methods</h3> Blood samples were obtained at four time points during the trial. Hookworm specific IgG was measured using ELISA methodology and confirmed by Western blot analysis. Cytokine ELISAs were carried out on IL-4, IL-5, IL-10, TNF, IFN and IL17. Regulatory T cells were measured by flow cytometry utilising CD4, CD25 and Foxp3 antibodies. <h3>Results</h3> Hookworm infection was indicated by the presence of IgG–reactive 33-kDa bands on Western Blots, and was confirmed by an eosinophilia and positive faecal egg counts. Cytokine ELISAs demonstrated a statistically significant increase in IL5 in the intervention group. After 6 weeks of inoculation with hookworm larvae, the mean IL5 increase from baseline in the intervention group was 515% compared to 90% in controls. Trends of reduced levels of TNF and IL-17 were observed alongside increased levels of IL-10 in the intervention group. Patients on azathioprine and steroids were found to have significantly lower IFN and IL-10 levels compared to patients not on these drugs. <h3>Conclusion</h3> Successful establishment of hookworms in patients with active Crohn9s disease is haematologically demonstrated by a heightened eosinophilic response, and supported by Western Blot analyses and faecal egg counts. Raised IL-5 levels in patients treated with hookworms also suggest a switch to an anti-helminthic Th2 response. Insights into possible collaborative effects of hookworms and immunosuppressive drugs have been demonstrated. Individual patient cytokine profiles will be correlated against CDAI scores in order to clarify whether the Th2 response confers benefits in Crohn9s disease.
COAGULATION TIME OF BLOOD
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A HOPEFUL DECISION.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A punch-card laboratory reporting system with a cumulative summary format
Authors: J. M. Walsh
Journal: JAMA (1969)

A laboratory reporting system has been developed in a 500-bed community hospital which processes approximately 40,000 tests a month. The patient's chemistry and hematology data are updated daily in a cumulative summary format. This daily summary updates and replaces previous summaries in that calendar week. The summary format proves particularly valuable for serial determinations. This review of the daily reports permits the pathologist closer control of laboratory data while giving him a more active role with the clinician in data interpretation. The system offers many of the advantages of automated laboratory data processing for hospitals already equipped with punch-card systems. Pick-up lists, laboratory work schedules, interim ward reports, charges, and statistical reports are also produced.
Novel strategy for the prevention of recurrent hypersensitivity reactions to radiocontrast media based on skin testing
Authors: Ji-Hyang Lee, Oh Young Kwon, So-Young Park, Bomi Seo, Jin An, Yewon Kang, Ha-Kyeong Won, Woo-Jung Song, You Sook Cho, Hee-Bom Moon, Hyouk-Soo Kwon, Tae-Bum Kim
Journal: Journal of Allergy and Clinical Immunology (2019)
Do we really need more new medical schools?
Authors: R. H. Moy
Journal: JAMA (1971)

If the question were, "Do we need to expand opportunities for medical education?" there would be very little controversy. Thus, the real question is whether the need to expand opportunities is best served by the expansion of existing medical schools or by the creation of new schools. I have no categorical answer to this question, since it must be decided ultimately on the basis of local opportunities and resources. There are a number of cogent points that can be made in favor of considering the establishment of new centers of medical education, and I think that these should be considered by states, communities, and educational institutions as they look to their long-term needs. It is unfortunate that the shortage of funds at this time has made this a competitive question, since in more tranquil times the new medical schools may well be, and perhaps of necessity will be, complementary to
Examination of Adduct Formation In Vivo in the Mouse between Benzo(a)pyrene and DNA of Skin and Hemoglobin of Red Blood Cells
Authors: Lee Shugart, John Kao
Journal: Environmental Health Perspectives (1985)

We are interested in devising techniques which will allow us to measure and quantitate exposure to chemical carcinogens and which eventually can be used in risk analysis with humans. Our recent research with HPLC/fluorescence has demonstrated that we can detect, identify, and quantitate the binding of benzo(a)pyrene (BaP) with DNA of mouse skin. The technique not only allows femtomole amounts of BaPDE associated with DNA isolated from a single mouse skin to be detected using conventional instrumentation, but also establishes the stereochemical origin of the adduct, and has been employed in the investigation reported here to estimate the concomitant binding of BaP to hemoglobin in vivo. The temporal existence of BaPDE/DNA adducts in mouse skin over a 5-week period showed that at 35 days after treatment, approximately 15% of the initial adducts were still detectable even though DNA turnover would predict that they should have been deleted from the genome. The concentration of the major covalently bound adduct, anti-BaPDE/deoxyguanosine, relative to the total BaPDE/DNA adduct population remained essentially constant during the 5-week period. It is known that topically applied BaP is absorbed, metabolized, and excreted by the mouse. Examination of hemoglobin of mouse RBCs 24 hr after BaP treatment revealed covalent adduct formation exclusively via anti-BaPDE. The dose response of adduct binding to hemoglobin and DNA appeared to be similar.
Henry Orlando Marcy (1837-1924)
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Minerva Cardioangiologica, Turin
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Male fertility in hot environment
Authors: R. J. Levine
Journal: JAMA (1984)

<h3>In Reply.—</h3> We welcome the new analysis by Band and colleagues of data from the collaborative study to determine the efficacy of rifampin prophylaxis for prevention of secondary<i>H influenzae</i>disease. With the new analysis, statistical significance (<i>P</i>=.028) is achieved by combining data from children receiving the regimens of 10 mg/kg per dose and 20 mg/kg per dose. The authors changed their protocol during the study because the regimen of 10 mg/kg per dose proved unreliable in eradication of<i>H influenzae</i>colonization. Thus, it would seem inappropriate at this time to combine results from the regimen of 10 mg/kg per dose with those from children in the second phase of their study, during which the regimen of 20 mg/kg per dose was used. Was the decision to combine these data made before it was known to which group subsequent cases had been assigned and before analysis began? Would a
Clinical Features of Hemorrhage From Diverticula of the Colon
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal