tbuckley/cabot-search huggingface dataset:
Editorial board and contents
Authors: Dominic Kwiatkowski, Alejandro Sa ´nchez-Gracia, Xulio Maside, Brian Charlesworth, Jianjun Chen, Miao Sun, Laurence Hurst, Gordon Carmichael, Janet Rowley, Uwe Stra, Inbar Cohen-Gihon, Doron Lancet, Itai Yanai, Vila Carles, Jennifer Seddon, Hans Ellegren, James Birchler, Nicole Riddle, Donald Auger, Reiner Veitia, Bryan Gibbon, Brian Larkins, ´ric Austerlitz, Kenneth Hastings Trendsin, Robert Shields, Treasa Creavin, Helen Green, Manager Moulton
Journal: Trends in Genetics (2005)
Bone Density at Multiple Skeletal Sites in Amenorrheic Athletes
Authors: Monica L. Rencken
Journal: JAMA (1996)

<h3>Objective.</h3> —To determine if there is a generalized loss of bone mass at multiple skeletal sites in amenorrheic athletes compared with a group of eumenorrheic athletes. <h3>Design.</h3> —A case-control study examining the differences in bone mineral density (BMD) between amenorrheic and eumenorrheic athletes. <h3>Setting.</h3> —Seattle, Wash, and surrounding communities. <h3>Participants.</h3> —Forty-nine athletes, aged 17 to 39 years, were selected from those responding to advertisements in local sporting-goods stores and a trackand-field newsletter. Athletes were defined as amenorrheic if they had had fewer than 2 menstrual cycles in the last 12 months or none in the past 6 months, or eumenorrheic if they had had 10 to 13 cycles in the previous year. Only women who met these criteria, confirmed by tests for estradiol and progesterone levels, were enrolled in the study. <h3>Main Outcome Measures.</h3> —Bone mineral density measured by dual-energy x-ray absorptiometry. <h3>Results.</h3> —Amenorrheic athletes had significantly lower BMD (<i>P</i>&lt;.01) at the lumbar spine, femoral neck, trochanter, Ward triangle, intertrochanteric region, femoral shaft, and tibia. No difference was noted at the fibula. Body weight combined with months of amenorrhea and age of menarche predicted the BMD of the lumbar spine for amenorrheic athletes. Duration of amenorrhea and body weight of amenorrheic athletes predicted BMD at the femoral neck, trochanter, intertrochanteric region, and tibia. Weight alone predicted BMD at the femoral shaft and tibia. Age plus weight predicted lumbar BMD of eumenorrheic women. <h3>Conclusion.</h3> —Extended periods of amenorrhea may result in low bone density at multiple skeletal sites including those subjected to impact loading during exercise.
CNS Abnormalities After Hyperbilirubinemia
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Heterosexual Contact Is Not the Predominant Mode of HTLV-III Transmission Among Intravenous Drug Abusers
Authors: Umberto Tirelli
Journal: JAMA (1986)

<h3>To the Editor.—</h3> The very high prevalence of antibodies to human T-cell lymphotropic virus type III (HTLV-III) reported in the article by Clumeck et al<sup>1</sup>among groups of heterosexual Africans confirms that heterosexual contact plays a major role in the propagation of acquired immunodeficiency syndrome (AIDS), at least in Central Africa. To evaluate the role of heterosexual contact as opposed to the sharing of contaminated needles for HTLV-III transmission among intravenous (IV) drug abusers, between May and October 1985 we fully evaluated 30 couples in which both persons were IV drug abusers and 21 couples in which only one was an IV drug abuser (19 male and two female) while each had a heterosexual partner not belonging to known groups at risk for AIDS and a stable, long-term heterosexual relationship (&gt;1 year; median duration, 2.5 years). All IV drug abusers admitted frequent sharing of syringes. Sexual behavior, evaluated through
Laparoscopic cholecystectomy
Authors: V Drahonovský, J Hálek, P Smejkal, Z Oktábec
Journal: JAMA (1991)

The authors present an account of their experience assembled during one year with laparoscopic operations of the gallbladder. They indicated 248 patients for CHE incl. 237, i.e. 95.6%, for laparoscopic CHE. No deaths, no major complications, 6.5% conversions in elective indications, 23% in acute indications. Six patients with residual choledocholithiasis are in the authors' opinion a signal calling for more accurate detection of CHLDL before and during LCHE.
Recommended Adult Immunization Schedule--United States, 2003-2004
Journal: JAMA (2003)

Although the childhood immunization program in the United States has reduced the burden of vaccine-preventable disease substantially among children, substantial vaccine-preventable morbidity and mortality from diseases such as hepatitis A, hepatitis B, influenza, and pneumococcal infections continue to occur among adults. In February 2002, the Advisory Committee on Immunization Practices (ACIP) approved for the first time a schedule for the routine vaccination of persons aged > or = 19 years. The Adult Immunization Schedule has been accepted by the American Academy of Family Physicians (AAFP) and the American College of Obstetricians and Gynecologists (ACOG). ACIP will review and approve annually both the recommended adult and childhood immunization schedules. Together, these schedules provide a comprehensive summary of recommendations for prevention of vaccine-preventable diseases during the life span of persons in the United States.
Educational Council for Foreign Medical Graduates
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Effect of Filtered-Coffee Consumption on Plasma Lipid Levels
Authors: Roy E. Fried
Journal: JAMA (1992)

<h3>Objective.</h3> —To determine the effect of filtered-coffee consumption on plasma lipoprotein cholesterol levels in healthy men. <h3>Design.</h3> —Randomized controlled trial with an 8-week washout period followed by an 8-week intervention period during which men were randomly assigned to drink 720 mL/d of caffeinated coffee, 360 mL/d of caffeinated coffee, 720 mL/d of decaffeinated coffee, or no coffee. <h3>Setting.</h3> —Outpatient clinical research center in a university medical center. <h3>Participants.</h3> —One hundred healthy male volunteers. <h3>Outcome Measure.</h3> —Changes in plasma lipoprotein cholesterol levels during the intervention period. <h3>Results.</h3> —Men who consumed 720 mL of caffeinated coffee daily had mean increases in plasma levels of total cholesterol (0.24 mmol/L,<i>P</i>=.001), low-density lipoprotein cholesterol (0.17 mmol/L,<i>P</i>=.04), and high-density lipoprotein cholesterol (0.08 mmol/L,<i>P</i>=.03). No significant changes in these plasma lipoprotein levels occurred in the other groups. Compared with the group who drank no coffee, the group who drank 720 mL/d of caffeinated coffee had increases in plasma levels of total cholesterol (0.25 mmol/L,<i>P</i>=.02), low-density lipoprotein cholesterol (0.15 mmol/L,<i>P</i>=.17), and high-density lipoprotein cholesterol (0.09 mmol/L,<i>P</i>=.12) after adjustment for changes in diet. <h3>Conclusion.</h3> —Consumption of 720 mL/d of filtered, caffeinated coffee leads to a statistically significant increase in the plasma level of total cholesterol, which appears to be due to increases of both low-density lipoprotein and high-density lipoprotein cholesterol levels. (<i>JAMA</i>. 1992;267:811-815)
Pulmonary Function and Cardiopulmonary Bypass
Authors: Jawahar Ghia
Journal: JAMA (1970)

In adults and children, we measured airway resistance, compliance, alveolar-arterial oxygen gradient (100% oxygen), and dead space:tidal volume ratio early and late in anesthesia. Operations performed included cardiac bypass, and thoracic, abdominal, and surface procedures. Airway resistance increased when the pleura was opened. However, with intact pleurae even cardiopulmonary bypass had no effect on pulmonary performance. The deleterious effects of pleurotomy were alleviated by humidification of the inspired-gas mixture, and, during cardiopulmonary bypass, by providing intermittent deep breaths. We concluded that pleurotomy impairs pulmonary function primarily through retraction of the lungs and through retainment of secretions.
Elevated Creatine Kinase MB Isoenzyme Levels in Marathon Runners
Authors: Arthur J. Siegel
Journal: JAMA (1981)

Elevated serum creatine kinase MB isoenzyme (CK-MB) levels are regarded as a sensitive and specific marker for myocardial injury. Serum CK-MB was measured in male marathon runners during training and after competition. Mean serum CK-MB measured by a quantitative electrophoretic technique (normal, &lt;5 IU/L) showed borderline elevation during training with peaks 24 hours after competition. Mean CK-MB in 64 serum samples from 35 runners after competition was 130 IU/L or 8.3% of total CK activity. Levels of CK-MB averaging 26 times the upper limits of normal would usually be considered indicative of massive myocardial necrosis. Myocardial scintigraphy with technetium Tc 99m pyrophosphate was performed after competition in 12 randomly selected runners with a mean postrace serum CK-MB level of 160 IU/L or 13%. Infarct-avid ("hot-spot") scintigraphy, appropriately timed to detect underlying myocardial abnormalities, was within normal limits in all subjects. Normal results of infarct-avid scintigraphy coincident with marked serum CK-MB elevations strongly suggests that CK-MB arises from a noncardiac or skeletal muscle source in these runners. (<i>JAMA</i>1981;246:2049-2051)
Nathaniel Chapman (1780-1853), first president of the American Medical Association
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Therapy of Impetigo and Furunculosis
Authors: William C. Fritsch
Journal: JAMA (1970)

Pyoderma refers to any purulent disease of the skin, but this communication is restricted to only certain bacterial infections of the skin. Such infections can be either primary or secondary. Although "pyo-" indicates the presence of pus, certain instances of infection may not be pus-producing, for example, staphylococcal bullous impetigo.<sup>1</sup>Nonbacterial, pus-producing skin disease's, such as pustular psoriasis, are not discussed. Impetigo and furunculosis are the most significant bacterial infections of the skin. Chronic, deeper infections, termed ecthyma, probably start as impetigo. Both bacterial folliculitis and carbuncles are anatomical variants of furunculosis. Diffuse interstitial infection is termed cellulitis, and erysipelas is a superficial variant. Almost any dermatosis in which the stratum corneum is broken can become secondarily infected. colonization by pathogens ( coagulase-positive staphylococci and β hemolytic streptococci) is common, but manifest disease is relatively uncommon. There are skin diseases in which bacteria can be recovered from the lesions, but
Smoking History and Lung Cancer Survival in Women&lt;xref ref-type="fn" rid="fn2"&gt;2&lt;/xref&gt;
Authors: Hinds, M. Ward, Yang, Hong-Yi, Stemmermann, Grant, Lee, James, Kolonel, Laurence N.
Journal: JNCI Journal of the National Cancer Institute (1982)

Journal Article Smoking History and Lung Cancer Survival in Women Get access M. Ward Hinds, M.D., M.P.H., M. Ward Hinds, M.D., M.P.H. Search for other works by this author on: Oxford Academic PubMed Google Scholar Hong-Yi Yang, M.D., Hong-Yi Yang, M.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar Grant Stemmermann, M.D., Grant Stemmermann, M.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar James Lee, Ph.D., James Lee, Ph.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar Laurence N. Kolonel, M.D., Ph.D. Laurence N. Kolonel, M.D., Ph.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 68, Issue 3, March 1982, Pages 395–399, https://doi.org/10.1093/jnci/68.3.395 Published: 01 March 1982 Article history Received: 24 April 1981 Revision received: 28 October 1981 Accepted: 06 November 1981 Published: 01 March 1982
Athletic Injuries: Prevention, Diagnosis and Treatment
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Intra-arterial Administration of Procaine Hydrochloride After Arteriography
Authors: Willard J. Howland
Journal: JAMA (1967)

In spite of earlier investigator's reports, detailed oscillometric evaluation of peripheral circulation has not produced proof of a significant vasodilating effect of procaine hydrochloride in a series of 55 patients. No blood pressure alteration or other adverse effects occurred. However, prior to the intra-arterial administration of procaine, clinically significant arteriospasm was observed in 38 of 885 arteriographic procedures. After the routine use of procaine, clinical arteriospasm was observed in only two of 1,197 arteriographic procedures, and no arterial or venous thromboses complicated arteriography.
Ready Reference Handbook of Diseases of the Skin.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pathologic Features of Smooth-Muscle Tumors
Authors: Grier F. Starr
Journal: JAMA (1974)

SMOOTH-MUSCLE tumors of the intestinal tract are uncommon, but not rare. Experience indicates that the incidence is approximately 1 in 10,000 surgical specimens. The<i>Fascicle on Tumors of the Intestines</i>, edited by Wood,<sup>1</sup>indicates the relative incidence by site of these neoplasms in two previously recorded series (Table). The extensive monograph by Skandalakis et al<sup>2</sup>reviews a much larger number of cases, and shows a similar incidence of these tumors; there is a slight but insignificant predominance in men. The major age group involved is between 40 and 60 years; however, they have occurred in newborns and octagenarians.<sup>3</sup> The most common symptoms and signs produced by these tumors are melena, frequently recurrent abdominal pain, and the presence of an abdominal mass. It is of interest that several patients with smooth-muscle tumors of the small intestines have had previous explorations for upper gastrointestinal bleeding, with empiric gastric resections
The Osler Family
Authors: George T. Harrell
Journal: JAMA (1982)

William Osier became interested in descriptive biology as a schoolboy. His father was a priest, and his early university education emphasized the classics. After graduating in medicine, he taught in Canada and developed a close lifelong paternal relationship with William Francis, the son of a cousin. His practice was minimal in Montreal, Philadelphia, and Baltimore until his marriage to Grace Revere Gross. They married within months of publication of his textbook. Office practice and other consultations then generated substantial income. The pressures of practice and professional activities led to a move to Oxford, England, in hope of a more leisurely life. The Osler's home, The Open Arms, was a center of intellectual and social activity. Practice diminished, but fees increased. When World War I broke out, Sir William and Lady Osier actively joined the war effort. When their only surviving son, Revere, was killed in action, his death devastated both parents. (<i>JAMA</i>1982;248:203-209)
The Future of Stereotaxic Surgery
Authors: John E. Adams
Journal: JAMA (1966)

Stereotaxic surgery in humans was first reported in 1947<sup>1</sup>despite the fact that it has been per formed in animals since 1908.<sup>2</sup>In animals, the location of the target area in the brain could be determined from bony landmarks of the skull since the relationship between such landmarks and the various intracerebral, subcortical structures was remarkably constant. In humans, however, it became obvious that these relationships were not precise and internal landmarks, such as the anterior or posterior commissures, had to be established. By the use of such internal landmarks, it became possible to place an electrode into a predetermined, subcortical location with an error of not greater than 1 mm. Primarily because this precision<i>was</i>possible and because a properly placed stereotaxic lesion<i>could</i>abolish the rigidity and tremor of Parkinson's disease, stereotaxic techniques developed rapidly—by August, 1965, over 24,000 stereotaxic procedures had been performed in various countries.<sup>3</sup>
Age at Onset for Familial Epithelial Ovarian Cancer
Authors: Christopher I. Amos
Journal: JAMA (1992)

<h3>Objective.</h3> —To provide age-specific risks for ovarian cancer for relatives of ovarian cancer case patients. To characterize the age at onset for ovarian cancer for women with a single relative vs several relatives affected with ovarian cancer. <h3>Design.</h3> —Three previous studies were reexamined. The cumulative probability of ovarian cancer in first-degree relatives of women with histologically confirmed epithelial ovarian cancer and matched control subjects who participated in the Cancer and Steroid Hormone (CASH) Study was determined. The age of onset of ovarian cancer in women with and without relatives with ovarian cancer in a Washington, DC, case-control study was contrasted with that of women with at least two first-degree relatives studied at the National Cancer Institute (NCI). <h3>Results.</h3> —The CASH Study data showed that first-degree relatives of women with ovarian cancer had an increased risk for ovarian cancer, especially at older ages, when compared with relatives of control subjects. However, the median age at onset was the same among women in the Washington, DC, study with and without an affected relative. Among the women with an extensive family history of ovarian cancer studied at the NCI, the age at onset was considerably younger (47 years) than is typical for this disease (59 years). Of these, 17% had been diagnosed as having primary ovarian cancer by age 40 years. <h3>Conclusions.</h3> —Women who have one first-degree relative affected by ovarian cancer are at greater risk for ovarian cancer but not at an age earlier than the general population. The small proportion of women who have several affected relatives are, however, at a greater risk of early onset of ovarian cancer. Prophylactic oophorectomy may be reasonable for these women. (<i>JAMA</i>. 1992;268:1896-1899)
Awards, Appointments, Announcements
Journal: JNCI Journal of the National Cancer Institute (1995)

Journal Article Awards, Appointments, Announcements Get access JNCI: Journal of the National Cancer Institute, Volume 87, Issue 11, 7 June 1995, Pages 794–795, https://doi.org/10.1093/jnci/87.11.794 Published: 07 June 1995