Atrial Cardiopathy and Cardioembolic Stroke
Authors: Darae Ko, Emelia J. Benjamin
Journal: Annals of Internal Medicine (2022)

EditorialsJanuary 2023Atrial Cardiopathy and Cardioembolic StrokeDarae Ko, MD, MSc and Emelia J. Benjamin, MD, ScMDarae Ko, MD, MScSection of Cardiovascular Medicine, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, MassachusettsSearch for more papers by this author and Emelia J. Benjamin, MD, ScMSection of Cardiovascular Medicine, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, and Department of Epidemiology, Boston University School of Public Health, Boston, MassachusettsSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M22-3476 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Atrial fibrillation (AF) is the most common cause of cardioembolic stroke, accounting for 1 in every 4 ischemic strokes (1). According to the current paradigm, cardioembolic stroke in nonvalvular AF is caused by thrombus formation in the left atrium, most often in the left atrial appendage, from a lack of organized atrial contraction. Echocardiographic markers of blood stasis, including spontaneous echocardiographic contrast (smokelike pattern caused by swirling blood flow most often seen in the left atrium) and low left atrial appendage emptying velocity, are associated with increased risk for left atrial appendage thrombus and thromboembolism in AF (2). The presence ...References1. Tsao CW, Aday AW, Almarzooq ZI, et al. Heart disease and stroke statistics—2022 update: a report from the American Heart Association. Circulation. 2022;145:e153-e639. [PMID: 35078371] doi:10.1161/CIR.0000000000001052 CrossrefMedlineGoogle Scholar2. Goldberger JJ, Arora R, Green D, et al. Evaluating the atrial myopathy underlying atrial fibrillation: identifying the arrhythmogenic and thrombogenic substrate. 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[PMID: 35894866] doi:10.1093/europace/euac096 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Section of Cardiovascular Medicine, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, Boston, MassachusettsSection of Cardiovascular Medicine, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine, and Department of Epidemiology, Boston University School of Public Health, Boston, MassachusettsDisclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M22-3476.Corresponding Author: Darae Ko, MD, MSc, 72 East Newton Street, Boston, MA 02118; e-mail, [email protected]edu.This article was published at Annals.org on 20 December 2022. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoLeft Atrial Mechanical Dysfunction and the Risk for Ischemic Stroke in People Without Prevalent Atrial Fibrillation or Stroke Ankit Maheshwari , Faye L. Norby , Riccardo M. Inciardi , Wendy Wang , Michael J. Zhang , Elsayed Z. Soliman , Alvaro Alonso , Michelle C. Johansen , Rebecca F. Gottesman , Scott D. Solomon , Amil M. Shah , and Lin Yee Chen Metrics January 2023Volume 176, Issue 1Page: 131-132KeywordsLeft atriumStrokeThromboembolismThrombosis ePublished: 20 December 2022 Issue Published: January 2023 Copyright & PermissionsCopyright © 2022 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...