tbuckley/cabot-search huggingface dataset:
General Pathology.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Neutrophilic urticaria
Authors: MARGOT S. PETERS, R.K. WINKELMANN
Journal: British Journal of Dermatology (1985)

Eight patients with neutrophilic urticaria were identified in a 5-year biopsy experience (1980-1984). All patients had a neutrophilic venulitis without fibrinoid necrosis, hemorrhage, or leukocytoclasia. Four patients had a history of angioedema, and two had a personal history of atopic disease. Results of laboratory studies, including complement and protein values and antibody serologic tests, were normal. All patients responded to antihistamine agents. Despite occasional clinical or histologic diagnoses of vasculitis for such cases in the past, the clinical, laboratory, and histologic features and the therapeutic course of these patients are compatible with a phase or type of chronic urticaria.
PROFESSIONAL JEALOUSY
Authors: Edwin P. Jordan
Journal: JAMA (1952)

<h3>To the Editor:—</h3> The letter on professional jealousy written by Drs. Levine, Barbour, and Stephens, and published in the correspondence section ofThe Journal(<b>148</b>:765 [March 1] 1952) raises a question that may well be expanded in various directions. Professional jealousy between physicians casts no honor on the profession and has long been recognized for what it is by those outside. There are many literary references to this unsavory trait; the thread runs all through the novel "Dr. Throne," by Anthony Trollope. "And thus Dr. Thorne became settled for life in the little village of Greshamsbury.... In doing so, he was of course much reviled. Many people around him declared that he could not truly be a doctor, or, at any rate, a doctor to be so called; and his brethren in the art of living around him, though they knew that his diplomas, degrees, and certificates, were all
Traumatic rupture of aorta; special reference to automobile accidents
Authors: R. M. Greendyke
Journal: JAMA (1966)

Forty-two cases of traumatic rupture of the aorta were encountered in 1,259 medicolegal autopsies performed in a four-year period. One of every six victims of fatal auto accidents sustained aortic rupture. This lesion was generally associated with accidents characterized by violent and sudden deceleration. Thirteen of 25 passengers and drivers sustaining aortic rupture were ejected from the automobiles. It is important to consider the possibility of aortic rupture in survivors of automobile crashes.
LETTER FROM NEW YORK.
Authors: None P. B. P.
Journal: JAMA (1889)

(FROM OUR OWN CORRESPONDENT.) Meeting of the Fifth District Branch of the New York State Medical Association—The Excursion to Milford, Pa.—Mr. Rudolph Hering's Report on the Sewage System of New York—The Suicide of Dr. Tilden Brown—The Power of an Artificial Electric Current to Destroy Life. The seventh special meeting of the Fifth District Branch of the New York State Medical Association was held at Port Jervis, Orange County, the last week in August. The place of meeting was the parlors of the Fowler House, and the session was one of interest both from a scientific and social point of view. The first paper was by Dr. W. B. Eager, of Middletown, on "The Use of Concentrated Lactic Acid." He had employed this agent with success in the case of epithelioma and other conditions, and, in fact, wherever acetic and nitric acids are generally used as escharotics. Dr. J. H. Hunt
A randomized controlled trial (RCT) of a supportive care package (SurvivorCare, SC) for survivors of colorectal cancer (CRC).
Authors: Michael Jefford, Karla Gough, Allison Drosdowsky, Lahiru Russell, Sanchia Aranda, Phyllis Noemi Butow, Jo Phipps-Nelson, Jane Young, Meinir Krishnasamy, Anna Ugalde, Dorothy King, Andrew Strickland, Michael Edward Franco, Robert helmut Blum, Catherine Johnson, Vinod Ganju, Jeremy David Shapiro, Geoffrey Chong, Julie Charlton, Penelope Schofield
Journal: Journal of Clinical Oncology (2015)

9566 Background: Colorectal cancer (CRC) and its treatments can cause distressing short and long-term side effects as well as significant functional consequences. Current models of follow-up do not adequately address these issues. We conducted a multi-center RCT of an innovative program (SurvivorCare (SC)); designed to have a beneficial effect on psychological distress, supportive care needs (SCN) and quality of life (QOL). Methods: At the end of active treatment for stage I-III CRC, eligible patients ( ≥ 18 years, adequate English) were randomized 1:1 to usual care (UC) or to UC+SC. SC comprised educational materials, needs assessment, an individualized survivorship care plan, nurse-led end-of-treatment session and three follow up (FU) phone calls. Distress (BSI-18), SCN (CaSUN) and QOL (EORTC QLQ-C30, CR29) were assessed at baseline, 2 (FU1) and 6 (FU2) months. Primary hypothesis: SC would have a beneficial effect on distress at FU1. Secondary hypotheses: SC would have a beneficial effect on (1) SCN and QOL at FU1; and (2) distress, SCN and QOL at FU2. 15 items assessed satisfaction with survivorship care. Sample size of 180 (90/arm) was based on 80% power, 2-sided alpha of 0.05, to detect a between groups difference of 3.6 on BSI-18 at FU1. Outcome analysis was ITT. Results: Of 221 patients randomized (111 UC, 110 SC), 4 were ineligible and 1 lost to FU, leaving 110 UC, 106 SC. Groups appeared well balanced. Median age was 64, 52% male, 56% colon, 35% rectal cancer, 10% overlap. Stage I 7%, II 22%, III 71%. Intervention fidelity was acceptable. Baseline distress and QOL were similar to population norms. Between groups differences in distress at FU1 (primary outcome), distress at FU2 and SCN and QOL at FU1 and FU2 were small and non-significant. SC patients were more satisfied with survivorship care than UC patients (significant differences on 10 of 15 items). Conclusions: The addition of SC to UC did not have a beneficial effect on distress, SCN or QOL outcomes but SC patients were more satisfied with survivorship care. Clinical trial information: ACTRN12610000207011.
The Kidney: Morphology, Biochemistry, and Physiology
Authors: Carl F. Anderson
Journal: JAMA (1970)

This book is the second in a proposed three-volume set dealing with selected topics concerning the kidney. Volume 2 contains seven separate monographs which include explants of the embryonic kidney, kidney and viruses, erythropoietin, experimental glomerular disease, pyelonephritis, toxic effects on the kidney, and kidney tumors. Mc-Cluskey and Vassalli's chapter on experimental glomerular disease is clear, thorough, and timely. Their description of immune complex diseases, antiglomerular basement membrane antibody diseases, and intravascular coagulation in experimental models with the possible relation to human disease is well-organized and comprehensible. Granoff's chapter concerning the kidney and viruses is stimulating, terse, and well referenced. Both volumes 1 and 2 deserve a place in larger reference libraries. Anyone interested in the kidney and its functions would benefit from a review of Rouiller's chapter in volume 1 concerned with general anatomy and histology of the kidney and the chapter in volume 2 dealing with experimental glomerular
A NEW BLOOD COAGULOMETER
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
In This Issue
Journal: JNCI Journal of the National Cancer Institute (1998)

A small but important number of all cases of cancers are inherited, and thus periodically clinicians need to have access to current information about the vari-0us inherited forms of cancer.To make this information readily accessible to busy clinicians-both primary-care physicians and specialists-who may only occasionally encounter patients with one of these diseases, Lindor, Greene, and the Mayo Familial Cancer Program (p.1039) have written their Concise Family Cancer
Correction: Medical research in Australia: Top of the pile: the institutes
Journal: BMJ (1991)

Siberia and the house divided into flats for workers on the collective farm.We made another house call to the widow of Saulietis, a writer of Latvian folk history.She is 99 years old now and has survived both Siberia, where she was sent on account of her husband's writing, and his death and that of her son in his 80th year.She received us in her decaying but still elegant summer house, Sauliesi.When the Latvians fought off the Russians in 1919 she was already 28, and she was 49 years old when on 21 July 1940 Soviet rule was installed and the deportations to Siberia began.'We returned tired to the flat where Juris lives with his wife, Solveiga, and baby son, Peter, on a wage lower than that of his chauffeur.It consists of a living room in which the family sleeps (Peter holding court from his cot), a small kitchen, a tiny bathroom festooned with nappies and offering a leaking supply of cold water, a hall used as a general store, and a balcony also used for drying clothes.Here I was hospitably entertained.During my stay, I saw an exhibition by the Latvian artist Vitolds Kucins, who paints the Latvian country- side and predicament.In one picture a shockhaired man stares at us, one blue eye concealed by his greatcoat collar.Behind him Latvian countryside stretches away-except for one piece ofit, which is half thrust into the man's pocket.The picture is entitled
Sane: insane
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Our Times: The United States, 1900-1925. II. America Finding Herself.
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract A1-09: Functional analysis of the chr13q22.1 pancreatic cancer risk locus suggests allele-specific effects on DIS3 expression with prognostic implications
Authors: Jason W. Hoskins, Abdisamad Ibrahim, Mickey Emmanuel, Sarah Manmiller, Jinping Jia, Hemang Parikh, Irene Collins, Kris Ylaya, Sean F. Altekruse, Stephen M. Hewitt, Gloria M. Petersen, Laufey T. Amundadottir
Journal: Cancer Research (2015)

Abstract A genome-wide association study (GWAS) of pancreatic cancer conducted within the NCI Cohort Consortium (PanScan I and II) identified pancreatic cancer susceptibility loci on chromosomes 1q32.1/NR5A2, 5p15.33/CLPTM1L/TERT, 9q34.2/ABO, and 13q22.1. The most significant single-nucleotide polymorphism (SNP) identified on 13q22.1, rs9543325, lies in a ~600 kb gene desert; the nearest genes are KLF5, KLF12, PIBF1, DIS3, and BORA (265–586 kb away). Imputation using the 1000 Genomes and DCEG reference datasets did not improve the GWAS signal, but produced a set of highly correlated SNPs for functional follow-up. We performed eQTL analysis to test for association between the genotypes of these functional candidate variants and expression of nearby genes. Among 64 normal derived pancreatic tissue samples, DIS3 expression showed the strongest association with a 30 bp indel variant in the risk locus (P = 4.8 × 10-4), indicating risk alleles associate with reduced DIS3 expression. Mutations in DIS3 have previously been identified in acute myeloid leukemia and multiple myeloma, and its expression has been correlated with metastatic potential in colorectal cancer, suggesting DIS3 is relevant to cancer biology. Chromosome conformation capture identified a physical interaction between the indel-containing locus and a region near the DIS3 promoter. Luciferase assay for regulatory function of this indel-containing locus revealed allele-specific silencer activity for the insertion allele. Supershift electromobility shift assay (EMSA) demonstrated binding of LEF1 specifically to the insertion allele of the indel, which contains two in silico predicted LEF1 binding elements. Finally, through immunohistochemical analysis, high DIS3 protein levels associated with better survival for pancreatic cancer patients (hazard ratio = 2.87, 95% CI = 1.49–5.53, P = 0.001). Our results suggest that at least one target gene for the pancreatic cancer risk variants on chr13q22.1 may be DIS3, and that the underlying biology may be mediated by the novel indel through a long-range repressive effect on DIS3 expression. Citation Format: Jason W. Hoskins, Abdisamad Ibrahim, Mickey Emmanuel, Sarah Manmiller, Jinping Jia, Hemang Parikh, Irene Collins, Kris Ylaya, Sean F. Altekruse, Stephen M. Hewitt, Gloria M. Petersen, Laufey T. Amundadottir. Functional analysis of the chr13q22.1 pancreatic cancer risk locus suggests allele-specific effects on DIS3 expression with prognostic implications. [abstract]. In: Proceedings of the AACR Special Conference on Translation of the Cancer Genome; Feb 7-9, 2015; San Francisco, CA. Philadelphia (PA): AACR; Cancer Res 2015;75(22 Suppl 1):Abstract nr A1-09.
THE NEED OF SANITARY LEGISLATION.
Journal: JAMA (1889)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction: Cancer in Cumbria and in the vicinity of the Sellafield nuclear installation, 1963-90
Journal: BMJ (1993)

to 385 (SD 75) ms.Their reaction time when symptomatic was also significantly longer than the repeat reaction time of the subjects who remained healthy (recruitment value 360 (SD 69) ms, repeat value 367 (SD 72) ms, second repeat value 373 (SD 124) ms) (p < 005).The subjects with influenza were 13% slower in performing the repeated numbers detection task than they had been on recruitment (recruitment value 555 (SD 79) ms, symptomatic value 627 (SD 132) ms, asymptomatic value 550 (SD 32) ms) and were significantly slower than the healthy controls (recruitment value 565 (SD 60) ms, repeat value 544 (SD 88) ms, second repeat value 549 (SD 72) ms) (p < 0 05).The infected subjects were also less accurate than the controls in the categoric search task (88% v 93%; p < 0 05).Influenza B had no effect on mood or on performance of the five choice serial response and focused attention tasks and free recall, delayed recognition memory, and logical reasoning tests.In the second study seven of 72 subjects with symptomatic infections had influenza B, and there were 14 asymptomatic controls.The subjects with influenza B showed a 19% increase in the reaction time for the 10 minute version of the variable fore period simple reaction time test when compared with the controls (symptomatic value 440 (SD 82) ms, control value 369 (SD 79) ms, p < 005).One month later the two groups had similar reaction times.As before, influenza B had no effect on the five choice serial response task or mood.
A PLAN FOR A GRADUATE COURSE IN PEDIATRICS FOR GENERAL PRACTITIONERS
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Humanism and the medical past
Authors: L. S. King
Journal: JAMA (1970)

The word "humanism" has almost as many meanings as there are people who use it. As a historical term it has many fine shadings, important for understanding the past, while in the present it has distinct meanings in different categories—theology, philosophy, education. And within each of these are further shadings. To discuss humanism in medicine we must limit ourselves sharply. In the realm of education the humanist would say that our medical teaching lays too much stress on science and not enough on a group of subjects loosely called the humanities. I will not try to define or even enumerate these but they have in common an emphasis on man as a person, as an individual who has ideals and values; who faces conflicts and disappointments; who experiences joys and fulfillment; who lives in a world of qualities and meanings, the rich real world portrayed in novels and poetry and
Modified Respirator Aids Infants
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ramucirumab Extends Survival in Advanced NSCLC
Journal: Cancer Discovery (2014)

Abstract Results from the phase III REVEL study show that ramucirumab, in combination with docetaxel, prolongs overall survival by 1.4 months for patients with relapsed stage IV non–small cell lung cancer. Ramucirumab's effects appear consistent across both squamous and non-squamous forms of the disease.