tbuckley/cabot-search huggingface dataset:
Heat artifact simulating adenocarcinoma of fallopian tube
Authors: J. L. Cornog
Journal: JAMA (1970)

<h3>To the Editor.—</h3> In the unusual case here described, artifact caused by accidental exposure to heat of a surgical specimen from a tubal ligation led to the initial pathologic diagnosis of adenocarcinoma of the fallopian tube. Although the circumstances which occasioned this mistake are rare, awareness of this potential source of diagnostic error is worthwhile, since prior knowledge is all that is necessary for its complete avoidance. <h3>Report of a Case.—</h3> A 41-year-old married woman, gravida, para 4, was admitted for evaluation of recurrent intermenstrual spotting, which had previously occurred in 1956 and 1966; both episodes responded to dilatation and curettage. The remainder of the medical history was noncontributory. Pelvic examination showed a healthy lower genital tract, a normal uterus, and normal adnexa. A dilatation and curettage and Pomeroy tubal ligation were performed. No gross abnormalities were noted at surgery. The curettings were diagnosed histologically as early secretory endometrium. On
Host immunity contributes to the anti-melanoma activity of BRAF inhibitors
Authors: Deborah A. Knight, Shin Foong Ngiow, Ming Li, Tiffany Parmenter, Stephen Mok, Ashley Cass, Nicole M. Haynes, Kathryn Kinross, Hideo Yagita, Richard C. Koya, Thomas G. Graeber, Antoni Ribas, Grant A. McArthur, Mark J. Smyth
Journal: Journal of Clinical Investigation (2015)

An error was made during the preparation of Figure 6B, resulting in more lines on the graph than the number of samples shown.In addition, the legend for Figure 6 did not indicate that WT plus vehicle and WT plus PLX4720 samples shown in Figure 6B are also presented in Figure 6C.All samples in these panels were derived from the same set of experiments.The authors have revisited the statistical analyses to account for the number of comparisons appropriately.The corrected Figure 6 and sentences for the legend are below.
Idoxuridine in the treatment of cutaneous herpes simplex
Authors: M. B. Corbett
Journal: JAMA (1966)

Idoxuridine (0.1%) in polyvinyl alcohol (1.4%) was applied to recurrent herpes simplex lesions in human beings. Comparison by double-blind placebo control techniques revealed that idoxuridine significantly shortened the healing time of herpes lesions when the medication was applied early in the course of the disease. <h3>Background of Disease</h3> Herpes simplex virus infections have been a problem to physicians from two standpoints. Herpes simplex keratitis has been a major cause of blindness in the United States for many years, particularly since gonorrheal ophthalmia became a rarity. Recurrent herpes simplex skin infections have always been frustrating for the physician. The single attack has not usually been serious. However, the large number of people afflicted often have frequent attacks. These clinical facts, as well as research literature, force admissions that all previously available therapy, when subjected to critical, controlled evaluation, has proved ineffective. (The less common types of herpes, such as primary herpetic
STEPHEN HALES, PARSON AND PHYSIOLOGIST
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Response to deltoid muscle injection of hepatitis B vaccine after failure to respond to gluteal injections
Authors: D. J. Weber
Journal: JAMA (1986)

Resuscitation: Is It Effective?"Cummins and Eisenberg1 state: "Clinical evidence provides strong support for efforts to increase the percent of persons in cardiac arrests who receive early bystander CPR [cardiopulmonary resuscitation].These efforts do no harm and clearly save lives."We wish to report a subgroup of patients in whom early bystander-initiated CPR may be dramatically successful.Cardiac arrest induced by lightning or electricity is a unique injury because all patients may survive if CPR is promptly instituted.The potential success rate in this sub- group can be compared with success rates for resuscitation attempts in
Sporty Spots
Authors: Helena Jenkinson, Beau DiCicco
Journal: JAMA Dermatology (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
American Cancer Society National Conference—Breast Cancer-1983
Journal: JNCI Journal of the National Cancer Institute (1983)

Journal Article American Cancer Society National Conference—Breast Cancer-1983 Get access JNCI: Journal of the National Cancer Institute, Volume 70, Issue 2, February 1983, Pages 387–388, https://doi.org/10.1093/jnci/70.2.387-d Published: 01 February 1983
Error in Table 2
Authors: Shawn Rangel, Jonathan Hills-Dunlap
Journal: JAMA Pediatrics (2019)

John Bian, PhD; Kathryn K. Cristaldi, MD, MHS; Andrea P. Summer, MD, MSCR; Zemin Su, MS; Justin Marsden, BS; Patrick D. Mauldin, PhD; James T. McElligott, MD, MSCR
The hospice movement
Authors: M. Gideon
Journal: JAMA (1979)

<h3>To the Editor.—</h3> My article "Large Cell Bronchogenic Carcinoma: Prolonged Disease-Free Survival Following Chemotherapy," which was published inThe Journal(241:594, 1979), attracted considerable attention. I designated the case as a large cell carcinoma because of the following: (1) The original pathological diagnosis made in 1973 was that of an "undifferentiated carcinoma." (2) This diagnosis was confirmed in 1973 by the pathologist then in charge of the Division of Surgical Pathology at the University of Minnesota, who reviewed the tissue. (3) Elements consistent with large cell carcinoma were present. (4) The tumor was not designated by any of the original pathologists as a small cell carcinoma. After the article's publication, Dr Mary Matthews, of the National Cancer Institute-Veterans Administration Medical Oncology Branch, VA Medical Center, Washington, DC, requested that the slides be sent to her for review. It is her impression that this case represents what is currently being classified as
Cause of death. Proper completion of the death certificate
Authors: T. Kircher
Journal: JAMA (1987)

Mortality statistics derived from death certificates are the only continuously collected, population-based, disease-related information available in most parts of the world, including the United States. For this reason, every effort must be made to ensure that the most specific, accurate, and complete information regarding cause of death is registered on death certificates. This article discusses identification of the underlying and immediate causes of death, the mechanism and manner of death, and completion of the medical certification section of the death certificate. Examples are given to illustrate the appropriate sequencing of causal information and the selection of the proper underlying cause of death. (<i>JAMA</i>1987;258:349-352)
Unreviewed Reports
Authors: R Dennison, J Britton
Journal: BMJ (1984)

Penetrating anorectal injury: cautionary tale for surgeons Impalement injuries of the anorectum are difficult to manage.Depending on the dimensions of the impaling object and the force of impact, intra-abdominal organs may be damaged.During a neuro- surgical operation the stool needed adjustment.When the surgeon replaced his weight the top of his swivel stool completely separated and he impaled himself on the shaft.A partial tear of the external sphincter required repair, and a colostomy was necessary for two months to allow a periprostatic haematoma to resolve.A trivial disturbance of continence remains.Ideally theatre stools should.notcome apart and should be checked before use.
A survey of medication treatment for hyperactive/inattentive students
Authors: D. J. Safer
Journal: JAMA (1988)

Since 1971, the Baltimore County Health Department has conducted nine biannual surveys of school nurses in all of the county's public and private schools to determine the prevalence of medication treatment for hyperactivity/inattentiveness among students. The results reveal a consistent doubling of the rate of medication treatment for hyperactive/inattentive students every four to seven years such that in 1987,5.96% of all public elementary school students were receiving such treatment. Related trends from 1971 to 1987 have been that stimulants increased from 76% to 99% of the medication prescribed; methylphenidate hydrochloride rose from 40% to 93% of the total; the male-female ratio dropped from an average of 8:1 to 5:1; the rate of medication treatment for hyperactive/inattentive students rose faster in secondary than in elementary schools; and 25% of students receiving stimulant medication in 1987 were in special education classes or schools. (<i>JAMA</i>1988;260:2256-2258)
Erratum: Mapping the HLA ligandome landscape of acute myeloid leukemia: a targeted approach toward peptide-based immunotherapy
Authors: C Berlin, D J Kowalewski, H Schuster, N Mirza, S Walz, M Handel, B Schmid-Horch, H R Salih, L Kanz, H-G Rammensee, S Stevanović, J S Stickel
Journal: Leukemia (2016)
Six-Year Follow-up of the Norwegian Multicenter Study on Timolol after Acute Myocardial Infarction
Journal: New England Journal of Medicine (1985)

The original Norwegian Multicenter Study on Timolol after Myocardial Infarction was a double-blind, randomized study comparing the effect of timolol with that of placebo for up to 33 months after acute myocardial infarction. The initial results showed that the cumulated mortality rate was 39.4 per cent lower among 945 patients randomly assigned to timolol treatment than among 939 patients randomly assigned to placebo (P = 0.0003). After the end of the double-blind period the majority of participating patients in the timolol group continued to receive beta-adrenergic blockade, whereas the majority of placebo-treated patients continued without such blockade. During an extended follow-up of participating patients up to 72 months after randomization, the mortality curves of the two groups continued to rise in parallel. Cumulated mortality rates were 32.3 per cent in the placebo group and 26.4 per cent in the timolol group (P = 0.0028). We conclude that the previously observed early beneficial effect of beta-adrenergic blocking therapy is maintained for at least six years after infarction. (N Engl J Med 1985; 313:1055–8.)
Chemical Modulation of Airway Epithelial Permeability
Authors: R. C. Boucher
Journal: Environmental Health Perspectives (1980)

The mucosal surface of the conducting airways has specialized structures for respiratory defense. Glands secret mucus that may act as a barrier to particle penetration and participate in particle clearance. Intraepithelial irritant receptors aid in particle clearance through airway constriction and cough. The epithelium acts as a barrier to the penetration of inhaled material into the airway wall. Morphologic studies have identified the tight junctions adjoining respiratory epithelial cells as the principal barrier to passive solute translocation across the airway. New approaches have been used to study airway epithelial function. Use of excised canine trachea mounted in Ussing chambers has permitted quantitative estimates of probe molecule permeation, the correlation of permeability with bioelectric properties, and estimation of equivalent pore radii. Probe molecule diffusion across canine trachea [mean transmucosal electric potential difference (PD) = 33 mV, lumen negative] is directly related to conductance (2.9 mS/cm2) and is compatible with an equivalent pore radius of 7.5 nm. Direct measurement of tracheal PD in vivo (-29 mV) facilitates study of the genesis of the biopotential in intact animals. Measurement of the movement of HRP by radioimmunoassay has allowed correlation of the rate of probe flow across airway walls in vivo with ultrastructure. These approaches lend themselves to the study of pharmacologic and toxicologic effects on epithelial function. Antigen challenge, diethyl ether, and unfractionated cigarette smoke have been shown to increase epithelial permeability to HRP accompanied by ultrastructural evidence of tight junctional damage. Application of pharmacologic agents, e.g. amphotericin, ouabain, onto the respiratory epithelium induces similar changes in in vitro and in vivo PD. We conclude that techniques that have been used to measure permeability and transport in other epithelia may help elucidate modes of action of environmental agents on airways.
Abdominal Radiology
Authors: Yolanda T. Adler
Journal: JAMA (1982)

In these days of advanced technology we tend to forget that a lot of information is often present in some of the simple, less expensive procedures, if only a well-informed and conscientious radiologist takes the time to elicit it. It is therefore timely to find a comprehensive review of one of the most common examinations performed in the radiology department, the plain film of the abdomen. This book is organized according to radiological findings and anatomic structures, making it easy to look up topics such as calcifications, gas collections, and abdominal masses. It is profusely illustrated, and although the subject necessitates considerable reduction in size of the reproduced radiographs, the figures are still clear and most of the time the findings are easy to appreciate. Good anatomic drawings in many sections of the book are helpful. When necessary, the plain film is accompanied by other examinations such as barium studies,
Rating the Severity of Tissue Damage
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Wiener Medizinische Wochenschrift
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INFANTILE HYPERTROPHIC STENOSIS OF THE PYLORUS.
Authors: Frank Bunts
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Continuing Medical Education
Authors: Arthur Osteen
Journal: JAMA (1986)

<h3>ACCREDITATION</h3> The Accreditation Council for Continuing Medical Education (ACCME) completed its first five years of operation at the end of 1985. One of the Council's primary responsibilities is to directly survey and accredit sponsors of continuing medical education (CME) activities designed for a national or multistate audience of physicians. Table 1 presents information on ACCME accreditation activities for the five-year period 1981-1985. The number of applicants for accreditation is given for each of the five years as well as the various kinds of accreditation decisions made by ACCME on these applications. Two-year provisional accreditation is given only to applicants for initial accreditation. At the end of this time, the applicant is resurveyed and is usually given either accreditation or nonaccreditation. In a few instances, the provisional accreditation is extended for another two years. From the data in Table 1, it appears that the ACCME awarded provisional accreditation to fewer applicants
Shall The Journal be Removed to Washington?
Authors: T. D. Crothers
Journal: JAMA (1891)

<h3>To the Editor:</h3> — Dr. Comegys' letter in last week'sJournalwas a most agreeable surprise to me. I feel that he has given a new interest to the subject, and made in reality a most convincing plea to haveThe Journalremain where it is. One or two more letters of this character would practically fixThe Journalat Chicago for at least a generation to come. While the text of his letter seems to favor a removal to Washington, the reasons he urges are the very strongest which have been published, showing the necessity of leavingThe Journalwhere it is. The charge of conservatism and want of aggressive spirit is the highest compliment he could pay to the present management. The unwillingness of the managers to select a highly competent editor to direct things, is equally flattering; the history of medical journalism shows that only through prudent
Genotoxicity of N-Acetylarylamines in the Salmonella/Hepatocyte System
Authors: Snorri S. Thorgeirsson, Leonard C. Erickson, Carole L. Smith, Irene B. Glowinski
Journal: Environmental Health Perspectives (1983)

Coincubation of isolated, intact rat hepatocytes with Salmonella typhimurium tester strain TA 98 (Salmonella/hepatocyte system) has been employed to determine both bacterial mutagenicity and DNA damage in the hepatocytes following treatment with 2-acetylaminofluorene (AAF) and other AAF derivatives. In vivo pretreatment of rats with either 2,3,7,8,-tetrachlorodibenzo-p-dioxin (TCDD) or 3-methylcholanthrene (MC) markedly increased both DNA damage and bacterial mutation frequency upon incubation of AAF or 2-aminofluorene (AF), in this system. The increase in damage to the hepatocyte-DNA was more pronounced after AAF treatment than by that for AF, while the increase in bacterial mutation frequency was greater after AF treatment. Hepatocytes treated with paraoxon prior to exposure to N-hydroxy-2-acetylaminofluorene (N-OH-AAF) or N-acetoxy-2-acetylaminofluorene (N-OAc-AAF) partially inhibited the DNA damage caused by these agents, as well as inhibiting the bacterial mutagenicity of N-OAc-AAF (50% inhibition) and N-OH-AAF (80% inhibition). These data indicate that metabolic processes other than those involved in activating AAF and its derivatives into a bacterial mutagen(s) may contribute to the genotoxic effects of these compounds. Thus, the Salmonella/hepatocyte system may provide a useful model in which to study the relative role of the various metabolic processes associated with the carcinogenic effects of N-acetylarylamines.