tbuckley/cabot-search huggingface dataset:
Statistical Methods for Medical and Biological Students
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Awards, Appointments, Announcements
Journal: JNCI Journal of the National Cancer Institute (1995)

Journal Article Awards, Appointments, Announcements Get access JNCI: Journal of the National Cancer Institute, Volume 87, Issue 2, 18 January 1995, Pages 84–85, https://doi.org/10.1093/jnci/87.2.84 Published: 18 January 1995
Hematuria Caused by Varicella Lesions in the Bladder
Authors: Arjan D. Amar
Journal: JAMA (1966)

HEMATURIA resulting from chickenpox lesions must be rare indeed. It is not mentioned in any of several pediatric textbooks,<sup>1-3</sup>or in the current edition of<i>Viral and Rickettsial Infections of Man</i><sup>4</sup>; and I have not been able to find a report of such an event. In a patient with hematuria and varicella, bleeding per urethra may be related to chickenpox lesions in the bladder, as exemplified in the following case. <h3>Report of a Case</h3> A 5-year-old boy was admitted to the hospital because of urinary frequency, dysuria, and passage of blood clots from the urethra, of four hours' duration. The mother reported that the child had been feverish and lethargic since the outbreak of varicella rash nine days before. His temperature was normal throughout his hospital stay. Scattered over the skin were chickenpox lesions in stages of crust formation and crust separation. A lesion on the chest, with
Persistently Decreased Brain Dopamine Levels and Cocaine
Authors: Richard Jed Wyatt
Journal: JAMA (1988)

<h3>To the Editor.</h3> —For many years, cocaine abuse has been a major public health problem, yet relatively little is known about cocaine's long-term biochemical effects. In particular, does cocaine produce persistent detrimental biochemical effects in former users? An important approach to this question has been to study the effects of administration of other stimulants to animals. Other stimulants, including amphetamine and methamphetamine, produce long-lasting depletion of animals' striatal dopamine levels—a reaction that has been attributed to a neurotoxic effect on terminals.<sup>1</sup>Our experiments indicate that cocaine persistently decreases brain dopamine levels—but, unlike other stimulants, cocaine selectively produces depletion of dopamine in the frontal cortex and hypothalamus. Since cocaine is a widely abused drug, these animal findings may have important clinical implications. <h3>Study.</h3> —For seven days, two groups of rats (15 total) were given 10 mg/kg of intraperitoneal cocaine or saline solution twice daily. (Two studies, using five and ten
Tuberculous Peritonitis
Authors: H Kaźmierczyk, S Owsianiak-Gajda
Journal: New England Journal of Medicine (1970)

The authors present the clinical picture of the tuberculous peritonitis and stress the potentialities of differential diagnosis. They drew on their diagnostic experience with tuberculous peritonitis occurring in the 1978-1987 period, and on their analysis of the clinical course of the disease in 7 patients (3 were under 40 years of age). The diagnosis should make use of laparoscopy supplemented with biopsy taken from the peritoneal wall using the "hot biopsy method", which enabled to achieve exact morphological verification. Nowadays, delayed or incorrect diagnosis can result in a serious clinical course of this rare complication of the disease.
Research Ethics and the Medical Profession: Report of the Advisory Committee on Human Radiation Experiments
Authors: A. C. o. H. R. Experiments
Journal: JAMA (1996)

The Advisory Committee on Human Radiation Experiments was convened by President Clinton in January 1994 in response to allegations of unethical practices in radiation experiments involving human subjects that were sponsored by the US government between 1944 and 1974. The committee's<i>Final Report</i>was released in October 1995. In addition to analyzing the history of the ethics of medical research involving human subjects, the committee reviewed current federal policies and procedures for protection of human subjects. In this article, the committee's findings are discussed as they relate to the patient-physician relationship, the issue of trust, and the specific role of the physician-investigator in all types of human experimentation. The committee found evidence of discussion of the conduct of human research at the highest levels of the government and within the medical profession, particularly with regard to risk, during the 1940s and 1950s. However, in both federal policy and professional practice, requirements for consent were more likely to apply to "healthy volunteers" than to patient-subjects (ie, those with disease or illness). Today, consensus exists that duties to obtain informed consent apply to<i>all</i>human subjects, whether healthy or sick, regardless of the risk or potential for medical benefit from participation in the research and regardless of the nature of sponsorship or funding (eg, federal, military, or private). Based on a finding of serious deficiencies in the current system of protections for human subjects, the committee offers a number of recommendations, including changes in institutional review boards; in the interpretation of ethics rules and policies; in oversight, accountability, and sanctions for ethics violations; and in compensation for research injuries. More than public policy changes, however, the committee recommends that the medical profession intensify its commitment to the ethics of research involving human subjects.
Journal of Physiology, London
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Holt's Diseases of Infancy and Childhood: A Textbook for the Use of Students and Practitioners.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cardiac Arrhythmias. Clinical Features and Mechanism of the Irregular Heart.
Journal: Annals of Internal Medicine (1928)

that must be used for these sections of only a medium degree of thinness, leaves the problems of finer cell structure untouched.In conclusion, it is to be stated with conviction that this book, with its clear exposition of the simple technique followed, its originality in the application of this in the new fields of histotopography and direct photography, its excellent illustrative material, and its fine colour reproduction, should be on the shelves of
Effects of Dose and Schedule of Methylnitrosourea on Incidence of Malignant Lymphoma in Adult Female Mice&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;
Authors: Joshi, Vijay V., Frei, Jaroslav V.
Journal: JNCI Journal of the National Cancer Institute (1970)

Journal Article Effects of Dose and Schedule of Methylnitrosourea on Incidence of Malignant Lymphoma in Adult Female Mice Get access Vijay V. Joshi, M.D., Vijay V. Joshi, M.D. Cancer Research Laboratory and Department of Pathology, University of Western Ontario, London, Ontario Search for other works by this author on: Oxford Academic PubMed Google Scholar Jaroslav V. Frei, M.D., Ph.D. Jaroslav V. Frei, M.D., Ph.D. Cancer Research Laboratory and Department of Pathology, University of Western Ontario, London, Ontario Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 45, Issue 2, August 1970, Pages 335–339, https://doi.org/10.1093/jnci/45.2.335 Published: 01 August 1970 Article history Received: 24 February 1970 Accepted: 05 May 1970 Published: 01 August 1970
Detection of pituitary tumors
Authors: R. S. Swerdloff
Journal: JAMA (1982)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CHICAGO MEDICAL SOCIETY.
Journal: JAMA (1883)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Potential Complications of High-Dose Epinephrine Therapy in Patients Resuscitated From Cardiac Arrest
Authors: Michael Callaham
Journal: JAMA (1991)

Adults resuscitated from nontraumatic cardiac arrest who received intravenous epinephrine in doses chosen by the treating physician and who survived at least 6 hours were studied to determine if high-dose epinephrine produced more complications than standard-dose. A total of 68 patients were enrolled and evaluated for postresuscitation complications attributable to epinephrine, using a two-tailed t test, and contingency analysis. The 33 patients receiving high-dose epinephrine and 35 patients receiving standard-dose epinephrine were similar in demographics and variables known to affect outcome. There was no difference in potential complications between groups except serum calcium, which was 1.97 mmol/L (SD, 0.20) in the high-dose epinephrine group and 2.10 (SD, 0.20) in the standard-dose group. Hospital discharge rates (18% in the high-dose vs 30% in the standard-dose group) and neurological status on discharge were not significantly different. High-dose epinephrine did not produce increased direct complications in this cardiac arrest population compared with standard-dose epinephrine. (<i>JAMA</i>. 1991;265:1117-1122)
Medical Management of Patients With Angina
Authors: Kanu Chatterjee
Journal: JAMA (1984)

WILLIAM Heberden first described angina pectoris as a distinct clinical entity in the latter half of the 18th century. However, not until the second half of the 19th century was the association between anginal episodes and the events that raised blood pressure recognized by Brunton, who also experimented with amyl nitrate to lower blood pressure for the relief of angina pectoris. Although amyl nitrate produced transient relief, it did not gain popularity because of the difficulty in proper usage. In 1879, when nitroglycerin was introduced, effective and prompt relief of anginal episodes became possible. Since then, a number of other vasodilators, β-adrenergic blocking agents, and, more recently, calcium entry blocking agents have been introduced for the treatment of angina pectoris. Furthermore, reperfusion of the potentially ischemic myocardium either by revascularization surgery or by coronary artery angioplasty have been proved to be useful and effective therapeutic modalities for the treatment of
Late-Breaking Clinical Trials Abstracts
Authors: Douglas Mann, Michael Debakey, Autumn Galbreath, San Antonio, E Braunwald, M Domanski, ; Fowler, ; Geller, B Gersh, ; Hsia, M Pfeffer, M Rice, Y Rosenberg, J Rouleau, Anne Juul, Jørn Wetterslev, Allan Kofoed-Enevoldsen, Torben Callesen, Gorm Jensen, Christian Gluud, Ronald Goldberg, David Kendall, Mark Deeg, John Buse, Anthony Zagar, Jane Pinaire, Meng Tan, Mehmood Khan, Alfonso Perez, Scott Jacober
Journal: Circulation (2005)

Background: Progressive left ventricular (LV) remodeling is part of the unfavorable natural history in patients with heart failure (HF).The CorCap Cardiac Support Device (CSD) is a mesh device that is implanted around the heart to reduce wall stress and the first therapy specifically designed to address LV remodeling.Early clinical studies have shown that the CSD is safe and associated with improvements in LV structure and function and patient symptoms.Design: This multicenter prospective trial enrolled 300 patients with NYHA Class III-IV HF and dilated cardiomyopathy.193 patients underwent mitral valve repair/replacement (MVR) and were randomized to either MVR alone or MVR plus CSD.107 patients were randomized to either continued optimal medical therapy alone or with the CSD.Patients were followed to a common closing date 12 months after the last patient was enrolled (median follow up 22 months).Results: The primary endpoint was a clinical composite with patients classified as improved, same or worsened based upon the occurrence of death, a major cardiac procedure indicative of HF progression and a change in NYHA class.Compared to the control group, the CSD group had more patients "improved" (38% vs. 27%) and fewer patients "worsened" (37% vs. 45%), yielding an odds ratio of 1.73 (1.07, 2.79; p ϭ 0.02).The CSD group had fewer major cardiac procedures (e.g.transplant, LVAD) compared to controls (19 vs. 33; p ϭ 0.01), a greater reduction in LV end diastolic (p ϭ 0.009) and systolic volumes (pϭ 0.017) and a greater improvement in sphericity index (pϭ0.026).Quality of life (Minnesota Living with HF and SF 36) was significantly improved in the CSD group (pϭ0.05 and p ϭ 0.015 respectively).Repeat hospitalizations and adverse events were not different between the two groups.Summary: In patients with progressive HF who are symptomatic despite optimal medical therapy, CSD implant reverses the natural history of HF, as indicated by an improvement in LV size and shape, an improved clinical score, fewer major cardiac procedures, and improvements in quality of life.This innovative therapy represents a new and effective approach for patients with enlarged hearts.
Diseases of the Nose, Throat and Ear: A Handbook for Students and Practitioners
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Motion, not immobility, advocated for healing synovial joints
Authors: Milan Korcok
Journal: JAMA (1981)

Orthopedic surgeons who "make a fetish out of applying plaster casts" should instead look to the use of motion to heal injured or diseased synovial joints. They should also realize, says Robert B. Salter, MD, professor and head of orthopaedic surgery at the University of Toronto Faculty of Medicine, that it is possible to regenerate articular cartilage with relative comfort and little inconvenience to the patient if one is willing to set aside plaster of Paris. Speaking to the 50th annual meeting of the Royal College of Physicians and Surgeons of Canada in Toronto, Salter said that the traditional concept that tissue, including cartilage, must be rested in order to heal "really is not valid" and the concept itself "must be put to rest." Salter was reporting not only on his long-term experimental investigations on the healing of fullthickness defects in articular cartilage in animals, but also on his subsequent
Identifying Substance Abusers at Preschool Age
Authors: Thomas B. Cole
Journal: JAMA (1996)

SOME CAN BE spotted when they're only 4 or 5 years old: children with a "high potential" for substance abuse in adolescence. Consider "Billy," a hypothetical case patient based on the clinical experience of Richard B. Heyman, MD, chair of the American Academy of Pediatrics' Committee on Substance Abuse. The child "had been an irritable infant, tough to console," Heyman recalled. "As Billy grew, he slept little, obeyed less, and generally consumed most of his parents' waking hours to keep him safe." Because the child was disruptive, easily distracted, and often hostile, he was evaluated for attention-deficit hyperactivity disorder (ADHD) at a very early age. After a battery of tests, ADHD was diagnosed. He was treated and seemed to perform a little better in school. "Certainly no child is locked into substance abuse at this age," cautioned George C. Comerci, MD, professor of pediatrics at the University of Arizona College
High Cloning Efficiency of Human Lymphoid Cells in Agarose Without Feeder Layers&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;
Authors: Kathleen N. Ayres
 4
Journal: JNCI Journal of the National Cancer Institute (1982)

A protocol has been developed that consistently gives high cloning efficiencies for human lymphoid cell lines (lymphoblastoid and lymphoma) in agarose without the use of feeder layers. This procedure utilizes a cloning medium that contains horse serum, α-ketoglutarate or oxalacetate, and high levels of glutamine.