Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial
Authors: Josep M Llovet, Masatoshi Kudo, Philippe Merle, Tim Meyer, Shukui Qin, Masafumi Ikeda, Ruocai Xu, Julien Edeline, Baek-Yeol Ryoo, Zhenggang Ren, Gianluca Masi, Mariusz Kwiatkowski, Ho Yeong Lim, Jee Hyun Kim, Valeriy Breder, Hiromitsu Kumada, Ann-Lii Cheng, Peter R Galle, Shuichi Kaneko, Anran Wang, Kalgi Mody, Corina Dutcus, Leonid Dubrovsky, Abby B Siegel, Richard S Finn, Simone Strasser, Alexander Thompson, Aflah Roohullah, William Sievert, Vladimir Andelkovic, Jennifer Knox, Janine Davies, Jamil Asselah, Mayur Brahmania, Habeeb Majeed, Luis Villanueva, Patricio Yanez Weber, Marcelo Garrido, Gonzalo Ignacio Pizarro, Nicolas Yanez, Ruocai Xu, Shuangyan Ou, Zhenggang Ren, Hongming Pan, Zhiqiang Meng, Kangsheng Gu, Xi Chen, Tao Zhang, Chunyi Hao, Peiguo Cao, Yabing Guo, Shukui Qin, Juxiang Xiao, Weijia Fang, Xin Wang, Yuxian Bai, Xiaoming Chen, Dong Yan, Hong Zhao, Jieer Ying, Carlos Bonilla, Olga Urrego, Angela Zambrano, Mauricio Lema, Juan Carlos Restrepo Gutierrez, Andres Cardona, Sandra Franco Millan, Madiedo Oscar, Victor Ramos, Philippe Merle, Samuel LeSourd, Julien Edeline, Jean-Pierre Bronowicki, Marc Bourliere, Stephane Cattan, Mohamed Bouattour, Laurent Mineur, Helene Regnault, Barbara Dauvois, Kornelius Schulze, Gunnar Folprecht, Andreas Geier, Oliver Waidmann, Fabian Finkelmeier, Marino Venerito, Marie-Luise Berres, Thomas Berg, Christian Lange, Hartmut Schmidt, Dirk T Waldschmidt, Michael Bitzer, Ray McDermott, Austin Duffy, Gianluca Masi, Vittorina Zagonel, Giuseppe Tonini, Fabio Piscaglia, Stefania Gori, Mimma Rizzo, Elisa Biscaldi, Luisa Foltran, Giuseppe Cabibbo, Masafumi Ikeda, Masatoshi Kudo, Hiroshi Aikata, Kazushi Numata, Hiroyuki Marusawa, Naoya Kato, Masayuki Kurosaki, Manabu Morimoto, Tatsuya Yamashita, Hironori Koga, Tsutomu Masaki, Ryosuke Tateishi, Yoshitaka Inaba, Tomohiro Arakawa, Yoshiyuki Suzuki, Norio Akua, Masahiro Kobayashi, Tetsuya Hosaka, Makoto Nakamuta, Noriko Oza, Shunsuke Kondo, Junji Furuse, Fumio Nagashima, Masayuki Kitano, Koichi Takaguchi, Baek-Yeol Ryoo, Ho Yeong Lim, Jee Hyun Kim, Tae-You Kim, Han Sang Kim, Carlos Hernandez Hernandez, Daniel Motola Kuba, Manuel Segura Gonzalez, Jesus Cabrera Luviano, Fidel Huitzil Melendez, Francisco Ramirez Godinez, Fernando Silva-Bravo, Edward Gane, Catherine Stedman, Mariusz Kwiatkowski, Lucjan Wyrwicz, Ewa Nowakowska-Zajdel, Leszek Kraj, Ewa Janczewska, Renata Surma-Wlodarczyk, Valeriy Breder, Marina Sekacheva, Rashida Orlova, Alexander Vasilyev, Ruslan Zukov, Vladimir Vladimirov, Beatriz Minguez, Ana Matilla Pena, Javier Fernandez Castroagudin, Manuel Romero Gomez, Jose Luis Lledo, Angel Rubin, Araceli Garcia Sanchez, Jose Calleja Panero, Ming-Chin Yu, Ying-Chun Shen, Yi-Hsiang Huang, Long-Bin Jeng, Ting-Tsung Chang, Sheng-Shun Yang, Shinn-Cherng Chen, Arunee Dechaphunkul, Tawesak Tanwandee, Apinya Leerapun, Mesut Seker, Hakan Harputluoglu, Irfan Cicin, Berna Oksuzoglu, Mehmet Bilici, Sema Sezgin Goksu, Mehmet Artac, Timucin Cil, Suayib Yalcin, Tim Meyer, Debashis Sarker, Ankit Rao, Daniel Palmer, Jeff Evans, Richard Hubner, Richard Finn, Susanna Ulahannan, Ahmed Zakari, Lynn Feun, Raed Al-Rajabi, Max Sung, Aiwu He, Adel Kardosh, Lipika Goyal, Daneng Li, Lipika Goyal, Minsig Choi, Juan Posada, Jyothi Dodlapati, Rachna Shroff, Saurabh Agrawal, Srivalli Gopaluni, Mehmet Akce, Olatunji Alese, Ari Baron, Richard Dunne, Arturo Loaiza-Bonilla, Catherine Frenette
Journal: The Lancet Oncology (2023)