Ultra-Widefield–Guided Swept-Source OCT Findings of Peripheral Vitreoretinal Abnormality in Young Myopes
Authors: Kyungmin Koh, Raimo Tuuminen, Sohee Jeon
Journal: Ophthalmology (2023)

PurposeTo evaluate the ultra-widefield fundus photography (UWF-FP)–guided swept-source OCT (SS-OCT) images of peripheral vitreoretinal abnormality (PVRA) in young asymptomatic myopes.DesignCross-sectional, single-center study.ParticipantsA total of 1966 eyes of 983 consecutive patients aged 18 to 42 years with refractive error in the spherical equivalent of < 0 diopters (D) who visited KEYE Eye Center, Seoul, Republic of Korea, for refractive surgery.MethodsThe prevalence of PVRA and their characteristics, including shape, location, presence of pigmentation, membrane, retinal breaks, and detachment, were evaluated. A logistic regression analysis was done to evaluate the risk factors of PVRA and the risk of retinal breaks or detachment among eyes with PVRA.ResultsAmong 1966 eyes, 317 (16.1%) had PVRA, and 182 (57.4%) and 135 (42.6%) had focal and linear lesions, respectively. The risk of PVRA was increased with axial length of the eyes (odds ratio [OR], 1.238, 95% confidence interval [CI], 1.112–1.379, P < 0.001), corneal astigmatism (OR, 1.320, 95% CI, 1.148–1.519, P < 0.001), presence of discrete margins of different retinal reflectivity (DMDRR; indicating outer retinal disruption from abnormal vitreoretinal traction) (OR, 1.751, 95% CI, 1.334–2.300, P < 0.001), and posterior vitreous detachment (PVD) at the posterior pole of the retina (OR, 1.833, 95% CI, 1.352–2.485, P < 0.001). Among eyes with PVRA, patient age (OR, 1.063, 95% CI, 1.008–1.121, P = 0.025), linear lesions (OR, 15.234, 95% CI, 7.891–29.407, P < 0.001), and multiple lesions (OR, 3.432, 95% CI, 1.780–6.620, P < 0.001) were independently associated with the presence of retinal breaks or detachment.ConclusionsThe follow-up for PVRA among young myopes should be personalized on the basis of their ocular characteristics, including asymmetric ocular expansion (axial length and astigmatism) and vitreoretinal interface status. The treatment plan for PVRA eyes should emphasize the greater risk of retinal breaks and detachment with increasing age and the presence of linear and multiple lesions.Financial Disclosure(s)Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article. To evaluate the ultra-widefield fundus photography (UWF-FP)–guided swept-source OCT (SS-OCT) images of peripheral vitreoretinal abnormality (PVRA) in young asymptomatic myopes. Cross-sectional, single-center study. A total of 1966 eyes of 983 consecutive patients aged 18 to 42 years with refractive error in the spherical equivalent of < 0 diopters (D) who visited KEYE Eye Center, Seoul, Republic of Korea, for refractive surgery. The prevalence of PVRA and their characteristics, including shape, location, presence of pigmentation, membrane, retinal breaks, and detachment, were evaluated. A logistic regression analysis was done to evaluate the risk factors of PVRA and the risk of retinal breaks or detachment among eyes with PVRA. Among 1966 eyes, 317 (16.1%) had PVRA, and 182 (57.4%) and 135 (42.6%) had focal and linear lesions, respectively. The risk of PVRA was increased with axial length of the eyes (odds ratio [OR], 1.238, 95% confidence interval [CI], 1.112–1.379, P < 0.001), corneal astigmatism (OR, 1.320, 95% CI, 1.148–1.519, P < 0.001), presence of discrete margins of different retinal reflectivity (DMDRR; indicating outer retinal disruption from abnormal vitreoretinal traction) (OR, 1.751, 95% CI, 1.334–2.300, P < 0.001), and posterior vitreous detachment (PVD) at the posterior pole of the retina (OR, 1.833, 95% CI, 1.352–2.485, P < 0.001). Among eyes with PVRA, patient age (OR, 1.063, 95% CI, 1.008–1.121, P = 0.025), linear lesions (OR, 15.234, 95% CI, 7.891–29.407, P < 0.001), and multiple lesions (OR, 3.432, 95% CI, 1.780–6.620, P < 0.001) were independently associated with the presence of retinal breaks or detachment. The follow-up for PVRA among young myopes should be personalized on the basis of their ocular characteristics, including asymmetric ocular expansion (axial length and astigmatism) and vitreoretinal interface status. The treatment plan for PVRA eyes should emphasize the greater risk of retinal breaks and detachment with increasing age and the presence of linear and multiple lesions.