tbuckley/cabot-search huggingface dataset:
"THE FLY IN COURT"
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Coarctation of the aorta with poststenotic aneurysm in a 71-year-old man
Authors: J. R. Stone
Journal: JAMA (1965)

AT AUTOPSY, a 71-year-old man who had died of pneumonia was found to have severe coarctation of the aorta, with concomitant hypertrophy of the collateral vessels and a poststenotic aneurysm. Since there have been very few recorded cases of coarctation of the aorta in patients surviving to this age, this case was thought to be worth reporting. <h3>Report of a Case</h3> A 71-year-old Mexican man was admitted to the hospital for the first time with complaint, by relatives, of extreme weakness of two years' duration and fever of recent onset. History from the patient was unobtainable as he was moribund. His temperature was 103 F (39.4 C) and blood pressure, 200/80 mm Hg. Rales were heard bilaterally. A chest film taken with a portable unit showed a mass in the region of the thyroid, a calcified mass in the left hilum, and rib notching. He died, in spite of receiving
Electrocardiographic ORS axis shift with left anterior hemiblock
Authors: A. A. Deliyannis
Journal: JAMA (1971)

<h3>To the Editor.—</h3> In response to the paper of Ewy et al (<b>215</b>:429-432, 1971), we wish to report a case of intermittent left anterior hemiblock that seems to be related to metabolic factors other than hyperkalemia. <h3>Report of a Case.—</h3> A 19-year-old boy was admitted to the hospital with severe renal failure secondary to chronic glomerulonephritis. He had been receiving lanatoside C intravenously in doses of 0.4 mg every other day. On admission he was confused, oliguric (300 mg/24 hr), and was vomiting. The blood pressure was 140 mm Hg systolic and 80 mm Hg diastolic, and remained within normal limits during his hospitalization. The ocular fundi were normal. An ejection systolic murmur was heard over the base and the apex of the heart. Examination of the roentgenogram revealed the cardiac silhouette to be within normal limits. The blood urea nitrogen (BUN) level was 660 mg/100 ml; hemoglobin level,
Book Review The Tennis Partner: A doctor's story of friendship and loss By Abraham Verghese. 347 pp. New York, HarperCollins, 1998. $25. 0-06-017405-6 Darwin's Audubon: Science and the liberal imagination By Gerald Weissmann. Approximately 309 pp. New York, Plenum, 1998. $28.95. 0-306-45981-7 The Power of Hope: A doctor's perspective By Howard Spiro. Approximately 289 pp. New Haven, Conn., Yale University Press, 1998. $35. 0-300-07632-0
Authors: Robert S. Schwartz
Journal: New England Journal of Medicine (1999)
Truth Behind Death Certificates
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"40 Million Get Checks From U.S. Treasury"
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Biological Photographers Honor Winning Entries
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Increasing reflux study duration progressively improves diagnostic consistency: a prospective study with 96 h wireless pH recordings
Authors: M. R. Fox, R. Sweis, D. Menne, A. Anggiansah, T. Wong
Journal: Gut (2011)

<h3>Introduction</h3> Previous studies suggest that prolonged ambulatory reflux monitoring can improve measurement consistency; however, previous reports were not analysed appropriately or adequately powered to determine the impact on key clinical parameters. The aim of this study was to assess measurement consistency for acid exposure time (AET) and symptom association with reflux events used to establish the diagnosis of GORD. <h3>Methods</h3> Acid reflux (pH) and symptom data were acquired by prolonged, 4 day, wireless pH recording (Bravo, Given Imaging). 163 consecutive patients presenting with predominantly typical reflux symptoms (heartburn, regurgitation) studied 2006–2009 with a record duration of &gt;3.7 days were studied (636 days). Data were exported in XML format, redundant symptom markers were removed in one pass with reflux detection. A cross-validation procedure assessed measurement variability (standard deviation (SD)) and diagnostic consistency of AET, symptom index (SI) and symptom association probability (SAP). The 4-day records were divided into 1-day sections and re-assembled as all possible subsets. Index parameters were computed for all subsets and labelled with a sequence identifier in the database. Bias due to self-referential comparisons was excluded (i.e., day 1 was not compared with day 123) and, also, no comparisons with 4-day results are given. Standard diagnostic thresholds were applied. In addition, the effect of varying threshold pH value used for reflux detection on diagnostic consistency was assessed. <h3>Results</h3> Measurement variability: There was no change in AET or SI over time; however, SAP increased progressively with study duration. Standard deviation (SD) was higher for 1-day than 3-day records for AET (+50% (confidence interval (CI): 10%…120%)) and SI (+100% (CI 120%…270%)) with no important difference across the observed range. Results for 2 days were intermediate. Similar findings were present for SAP (1 day vs 3 days at 95% SAP (+100% (CI 10%…700%); however, for this parameter measurement variability increased exponentially as SAP approached 100%. Diagnosis: Consistency for GORD diagnosis increased with study duration (table 1) for all parameters studied. <h3>Conclusion</h3> Increasing the duration of reflux studies progressively improves diagnostic consistency for GORD based on both AET and reflux-symptom association analysis independent of diagnostic threshold applied.
Duodenal Ulcer
Authors: Randolph A. Rovelstad
Journal: JAMA (1971)

This collection of papers, totaling 200 pages, for the most part reviews experimental and clinical research on psychosomatic factors related to gastric and duodenal ulcers. Except for a surgeon and gastroenterologist, the authors are oriented primarily toward psychological considerations. Of the ten chapters, one is written by a group from Homberg, Germany, another from Eisernhaugen, Germany. As with most books, the bibliography reflects a lag of approximately five or more years between the original date of publication and its incorporation into this volume. The physiologist will be disappointed with the sections on gastroduodenal physiology. These chapters provide good summary reviews but require supplementation from more current literature, particularly in considering inhibitory mechanisms influencing gastric secretion. The basic scientist will read with considerable skepticism the reviews of psychological characteristics of ulcer patients, and research in the psychiatric treatment of peptic ulcer. The clinical gastroenterologist will be more sympathetic, however. Few of
THU0037 Immune complex-induced inhibition of osteoclastogenesis is mediated via activating, but not inhibitory FCGAMMA receptors on myeloid precursor cells
Authors: L.C. Grevers, P.L. van Lent, T.J. de Vries, V. Everts, W.B. van den Berg
Journal: Annals of the Rheumatic Diseases (2013)

<h3>Background</h3> Rheumatoid arthritis is characterized by osteoclast-mediated bone loss. Co-stimulatory signalling via ITAM- and ITIM-coupled receptors is essential for osteoclast formation and function. The ITAM- and ITIM-coupled Fcγ receptors (FcγR) are known to play a crucial role in mediating inflammation and cartilage destruction in experimental arthritis, but their role in osteoclast-mediated bone loss is unknown. <h3>Objectives</h3> To investigate the role of FcγRs in osteoclastogenesis and osteoclast function. <h3>Methods</h3> Bone destruction was analyzed in arthritic knee joints of FcγRIIB-deficient, FcRγ-chain<sup>-/-</sup> (lacking expression of activating FcγRs), and wild type mice. Bone marrow-derived osteoclast precursors were differentiated <i>in vitro</i> towards osteoclasts in the absence or presence of immune complexes (ICs), and stimulated thereafter for 24 hrs with or without TNFα or LPS. Additionally, mature osteoclasts were stimulated with ICs. Experiments were analyzed for osteoclast formation, bone resorption, and the expression of FcγRs and osteoclast markers. <h3>Results</h3> Bone erosions and cathepsin K-positive osteoclast numbers were significantly increased during antigen-induced arthritis in the knee joints of FcγRIIB-deficient mice. All FcγR classes were highly expressed on bone marrow-derived osteoclast progenitors. On mature osteoclasts, as compared to macrophages, expression of the inhibitory FcγRIIB was similar, whereas expression of activating FcγRs was significantly lower. IC stimulation of mature osteoclasts neither affected their number nor their bone resorptive capacity. Differentiation of bone marrow-derived precursors in the presence of ICs significantly inhibited osteoclast formation, bone resorption, and expression of the osteoclast markers cathepsin K, CTR, DC-STAMP, and NFATc1. In the presence of ICs, osteoclastogenesis of FcγRIIB<sup>-/-</sup> precursors and bone resorption remained inhibited. In contrast, ICs could not inhibit osteoclast formation or bone resorption of FcRγ-chain<sup>-/-</sup> precursors. When IC-inhibited osteoclastogenesis was followed by stimulation with TNFα or LPS, the inhibitory effects of ICs were overruled. <h3>Conclusions</h3> Activating FcγRs, but not the inhibitory FcγRIIB, mediate IC-induced inhibition of osteoclastogenesis. In the presence of pro-inflammatory mediators like TNFα and LPS the inhibitory effect might be overruled. This suggests that the balance of FcγR-mediated induction of inflammation, through pro-inflammatory cytokine production, as well as the direct inhibitory effect of ICs on osteoclastogenesis determines the net effect on bone loss. <h3>Disclosure of Interest</h3> None Declared
Cardiopulmonary Resuscitation
Authors: Henry Turkel
Journal: JAMA (1986)

<h3>To the Editor.—</h3> The publication of the "Standards and Guidelines for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiac Care (ECC)" lucidly explains and illustrates the advances in this area.<sup>1</sup>It was encouraging to note that the technique of pediatric intraosseous infusion is discussed, since this method of gaining vascular access has often been overlooked.<sup>2,3</sup>Intratibial access can be obtained by use of a spinal needle with a stylet; however, it is much safer to use a proper bone marrow needle for any form of intraosseous infusion. Removing a plug of cortical bone rather than driving it inward by use of a trephinated tip reduces the threat of embolism.<sup>4</sup>Physicians often fail to consider the intrasternal route, which was safely used by so many medics and paramedics during and immediately following World War II, and which is particularly effective in the treatment of adults when the intravenous route is
PARENTAL CO-OPERATION IN THE MEDICAL INSPECTION OF SCHOOLS.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Studies in Adaption to Ambient Oxidant Air Pollution: Effects of Ozone Exposure in Los Angeles Residents vs. New Arrivals
Authors: Jack D. Hackney, William S. Linn, Ramon D. Buckley, Helen J. Hislop
Journal: Environmental Health Perspectives (1976)

To test the hypothesis that adaptation protecting against acute effects of ambient ozone (O3) exposures develops in Los Angeles residents, human volunteers were exposed to 0.4 ppm O3 under conditions simulating ambient pollution exposures. Blood biochemical, pulmonary physiological, and clinical responses were assessed. Los Angeles residents (N = 6) showed only minimal clinical or physiological response to O3, while new arrivals (N = 9) showed significant losses in pulmonary function and a tendency toward increased symptoms. Most biochemical responses did not differ significantly between residents and new arrivals. These results agree with others in suggesting that exposures to elevated ambient concentrations of O3 produce adaptation in a least some residents of photochemical pollution areas. The underlying mechanisms and long-term consequences of such adaptation are unknown.
A mirror-image relationship between temperature and pulse
Authors: B. S. Shah
Journal: JAMA (1979)

<h3>In Reply.—</h3> Drs Silverman and Wolff challenge the statement in our article that acanthocytosis is a feature of anorexia nervosa and state that none of their 88 cases were found to have acanthocytosis. On review of the literature referenced in our article, seven patients with anorexia nervosa and acanthocytosis were described.<sup>1,2</sup>In addition, we have subsequently seen a second case of anorexia nervosa with acanthocytosis. We are convinced that acanthocytosis is associated with some cases of anorexia nervosa. Mant and Faragher<sup>2</sup>state that acanthocytosis is transient and disappears after therapy is started. Perhaps the failure to report the finding in the series by Silverman and Wolff is due to the presence of mild disease or ongoing treatment.
Cecil Textbook of Medicine
Authors: Frank D. Gray
Journal: JAMA (1982)

<b>Review of General Internal Medicine: A Self-Assessment Manual,</b>edited by Lloyd H. Smith, Jr, and James B. Wyngaarden, 326+ pp, with illus, paper, $19.50, Philadelphia, WB Saunders Co, 1982. The latest edition of<i>Cecil</i>meets students' needs for medical science and technology admirably, and in deference to the feeling that our culture and general education have not done their jobs well, a humanistic tone is established by four excellent prefatory essays. A textbook of medicine must meet the needs of students before anything else, and one of these needs is consideration for the wants of patients. It is not reasonable, however, to expect that a textbook can help the student satisfy all patient wants. In Dr Smith's introductory essay he describes five of these wants, and four are related to humanistic attributes that make social intercourse a rewarding feature of our culture. These attributes are better molded by society and
Studien ueber die Anzahl der Blutplättschen beim Menschen.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
(5) Dyskeratosis congenita
Authors: M.J. Cheesbrough for, P.D.C. Kinmont
Journal: British Journal of Dermatology (1978)

Journal Article (5) Dyskeratosis congenita Get access M.J. Cheesbrough for, M.J. Cheesbrough for Children's Hospital, Nottingham Search for other works by this author on: Oxford Academic Google Scholar P.D.C. Kinmont P.D.C. Kinmont Children's Hospital, Nottingham Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 99, Issue s16, 1 December 1978, Pages 29–30, https://doi.org/10.1111/j.1365-2133.1978.tb15227.x Published: 01 December 1978
News from the American Heart Association
Authors: Mary Engle
Journal: Circulation Research (1965)

A record total of 235 papers will be presented at the American Heart Association's 1965 Scientific Sessions, selected from abstracts submitted for consideration.The sessions will be held from October 15-17 at the Hotel Americana, Bal Harbour, Fla.Advance programs will be sent to registrants who hold confirmed hotel reservations by September 30.The program booklet, which contains full details of each session, including the titles of papers and lectures to be presented, may also be obtained on request from local Heart Associations.Abstracts of the papers to be presented and others selected by the Committee on Scientific Sessions Program will be published in Circulation, Supplement No. 2, October 1965.Included in the same issue will be abstracts of papers presented at the Arteriosclerosis Council meeting.Covering a wide range of subjects of interest both to the clinician and the basic scientist, the papers will be presented at the Clinical Sessions, at concurrent sessions on various aspects of cardiovascular medicine and research, and at panels, lectures and symposia.A special event in the 3-day program will be the premiere screening of a new AHA medical film: "Cardiac Failure in Infancy-Manifestations and Management."The film, in color and running 30 minutes, will be introduced by Campbell Moses, M.D.,
Expectoration of bronchogenic tumor tissue
Authors: A. R. Goldstein
Journal: JAMA (1976)

BRONCHOGENIC carcinoma can present itself in a variety of ways. Some patients with this disease may have an abnormal chest roentgenogram but no symptoms. Others may have manifestations of metastatic disease. Although cough and hemoptysis are common, expectoration of tumor tissue as a part of the presenting complaint is extremely rare. <h3>Report of a Case</h3> A 78-year-old man came to the emergency room complaining of hemoptysis for the past 12 hours. Bleeding was initially brisk but had steadily decreased in amount. He had noted an irritative cough for about three months that did not respond to antibiotics, expectorants, or bronchodilators. The patient denied any acute dyspnea, sputum production, orthopnea, paroxysmal nocturnal dyspnea, angina, ankle edema, pleuritic pain, bone pain, or weight loss. He had a myocardial infarction at 51 years of age. He was being treated for chronic atrial fibrillation, with digoxin, 0.25 mg daily. He worked 42 years in