tbuckley/cabot-search huggingface dataset:
Vulvar Condylomata Acuminata in Prepubertal Females
Authors: D. A. Grace, J. A. Ochsner, C. R. McLain, J. P. Smith
Journal: JAMA (1967)

CONDYLOMA ACUMINATA of the vulva and periurethral regions are uncommon in children.<sup>1</sup>In general this condition tends to be misdiagnosed. Definitive diagnosis is dependent on biopsy of the lesion. We wish to report three cases seen at the Columbus Children's Hospital. <h3>Report of Cases</h3><h3>Case 1.—</h3> A 6-year-old white girl was admitted to the hospital in February 1949, with a three-month history of a small "growth" of the vulva and persistent greenish-yellow vaginal discharge. Results from the child's physical examination were normal except for several "pedunculated warty looking growths" about 0.5 cm in diameter located adjacent to the urethral meatus. Findings from a complete blood cell count (CBC), urinalysis, and vaginal culture were normal. A general anesthetic was given and the lesions were removed with electrocautery; the microscopic examination of the tissue revealed condyloma acuminata. The postoperative course was uncomplicated and the child was discharged on the fifth postoperative
Editorial board and contents
Authors: Josephine Pemberton, H Schaefer, David Wilkinson, Jessica Gurevitch, Dianna Padilla, Bryan Neff, Paul Sherman, Andrew Sih, Alison Bell, J Chadwick, Joel Cracraft, Michael Donoghue, Andy Purvis, Nils Stenseth, Geir Ottersen, James Hurrell, Andrea Belgrano, John Kocik, Paul Ehrlich, Ilkka Hanski, James Mallet, Bernard Crespi, Douglas Sheil, Anna Lawrence, John Wiens, David Rand, Robert Haney, Adam Fry, Navjot Sodhi, Lian Koh, Barry Brook, Peter Ng, Richard Mccourt, Charles Delwiche, Kenneth Trendsin, Katrina Lythgoe, Linsey Stapley, Laura Smith, Manager Moulton
Journal: Trends in Ecology & Evolution (2004)
POS0122 CENTRAL NERVOUS SYSTEM DEMYELINATING SYNDROMES IN SYSTEMIC LUPUS ERYTHEMATOSUS: RESULTS FROM “ATTIKON” LUPUS COHORT
Authors: D. Nikolopoulos, D. Kitsos, M. Papathanasiou, N. Kapsala, A. Grivas, O. Gioti, P. Garantziotis, A. Pieta, K. Voumvourakis, D. Boumpas, A. Fanouriakis
Journal: Annals of the Rheumatic Diseases (2022)

Background Central nervous system (CNS) demyelinating syndromes that occur in the context of SLE may represent a manifestation of neuropsychiatric lupus, or an overlap of SLE and multiple sclerosis (MS). The differential diagnosis between the two entities has important clinical implications, because the therapeutic management differs between the two conditions. Objectives To characterize CNS demyelinating syndromes in a large SLE cohort as neuropsychiatric SLE or SLE-MS overlap, using a multidisciplinary approach and existing diagnostic (MS) and classification criteria (SLE) Methods Patients from the “Attikon” lupus cohort (n=707) were evaluated for demyelinating syndromes. Clinical, laboratory and neuroimaging data were recorded for each patient. Following multidisciplinary evaluation and application of criteria, the demyelinating syndrome was attributed to either SLE or MS. Patients with transverse myelitis were not included in this study. Results We identified 26 patients with demyelinating syndromes (3.7%) with mean age at diagnosis 46.9 (SD 12.3) years and median disease duration at last follow-up 60 (IQR 52) months. Of them, 12 were diagnosed as primary SLE-demyelination (46.2%) and 14 as overlap SLE-MS (53.8%). The two groups did not differ with respect to rheumatologic and neurologic manifestations, or serologic findings (ANA, dsDNA, C3/C4, aPL, ENA). SLE patients with demyelination manifested mild extra-CNS disease mainly involving joints and skin, while severe non-CNS manifestations were rare. However, patients with SLE-demyelination were less likely to have elevated IgG index (OR 0.055 95% CI: 0.008-0.40) and positive oligoclonal bands (OR 0.09 95% CI: 0.014-0.56). SLE patients with primary demyelinating syndrome were less likely to exhibit brain lesions in the spinal cord, infratentorial, periventricular and juxtacortical regions. A single brain region was affected in 9 SLE-demyelination patients (75%), while all MS-SLE patients had multiple affected brain regions. MS-SLE overlap was associated with increased likelihood of neurologic relapses (OR 18.2, 95% CI: 1.76-188), while SLE-demyelination patients were less likely to exhibit neurological deficits (EDSS&gt;0) at last follow-up visit (50% vs. 78.6%in SLE-MS, respectively). Conclusion Demyelination in the context of SLE follows a more benign course compared to a frank SLE-MS overlap. Prolongation of follow-up will ascertain whether SLE-demyelination patients evolve to MS, or this is a bona fide NPSLE syndrome. Disclosure of Interests None declared
'Best Data Yet' Say Air Pollution Kills Below Levels Currently Considered Safe
Authors: Paul Cotton
Journal: JAMA (1993)

RESEARCHERS are reporting "robust" associations between premature mortality and air pollution levels that the US government currently deems safe in what appears to be the best study of its kind to date. The Harvard Six Cities Study found a 26% higher rate of premature death in the most vs the least polluted cities in which it tracked 8111 people for 14 to 16 years. "People who live in highly polluted cities die earlier. It's just that simple," says C. Arden Pope, PhD. What's more, the risk may be highest not from commonly known pollutants like ozone but from respirable particles with a diameter of 2.5 μm or less, small enough to penetrate deep into the lungs, says Pope. He is a visiting scientist at the Harvard School of Public Health, Boston, Mass, and associate professor at Brigham Young University, Provo, Utah. Particulate matter can include such things as carbon, hydrocarbon,
Cerebral Physiology in Dogs After Brain-Tumor Induction With Schmidt-Ruppin Rous Sarcoma Virus: Experiences With Radioiodinated Normal and Antiviral Immunoglobulin G&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;
Authors: Darell D. Bigner, Robert B. Fritz, Eugene D. Day
Journal: JNCI Journal of the National Cancer Institute (1969)

Brain tumors in dogs induced by the Schmidt-Ruppin strain of Rous sarcoma virus were found satisfactory as an animal model in which to study the localization of antiglioma antibodies. The effect of hydrocephalus on the distribution of antiviral and normal immunoglobulin G (IgG) in the brains of tumor-bearing and non-tumor-bearing hydrocephalic control dogs was measured. In vivo localization of antiviral IgG against the avian leukosis group-specific antigen in the brain of virus-inoculated dogs was observed. The importance of the route of injection and the necessity of both normal IgG control protein and nonvirus-inoculated hydrocephalic control dogs to detect localization were stressed.
Medical and Veterinary Entomology. A textbook for Use in Schools and Colleges as Well as a Handbook for the Use of Physicians, Veterinarians and Public Health Officials.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Independent Expression of Common and Private Tumor-Specific Cell Surface Antigens in Somatic Cell Hybrids Between Rous Sarcoma Virus-Transformed and Normal Cells&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;
Authors: Kuzumaki, Noboru, Oikawa, Tsuneyuki, Yamada, Toshiyuki
Journal: JNCI Journal of the National Cancer Institute (1984)

Journal Article Independent Expression of Common and Private Tumor-Specific Cell Surface Antigens in Somatic Cell Hybrids Between Rous Sarcoma Virus-Transformed and Normal Cells Get access Noboru Kuzumaki, Noboru Kuzumaki Search for other works by this author on: Oxford Academic PubMed Google Scholar Tsuneyuki Oikawa, Tsuneyuki Oikawa Search for other works by this author on: Oxford Academic PubMed Google Scholar Toshiyuki Yamada Toshiyuki Yamada Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 72, Issue 2, February 1984, Pages 387–393, https://doi.org/10.1093/jnci/72.2.387 Published: 01 February 1984 Article history Received: 08 April 1983 Revision received: 01 September 1983 Accepted: 06 October 1983 Published: 01 February 1984
Cell Biology/Neoplasia/Coeliac Free Papers
Authors: J.A. Eksteen, J.L. Smith, C. Tselepis, I. Perry, R.F. Harrison
Journal: Gut (2001)

tract.It has been suggested that faecal calprotectin might be a useful screening tool in distinguishing organic from functional bowel disease, especially in children.We report, for the first time, elevated faecal calprotectin in patients with diarrhoea due to pancreatic insuYciency.Method: A total of 115 patients (77 women: 38 men; age 19-85) with chronic non bloody diarrhoea were screened in this study.Both pancreatic elastase and calprotectin were assayed by ELISA in faecal samples (normal : calprotectin < 30 µg/g.elastase >150 µg/g.)Pancreatic imaging in those with low faecal elastase was carried out by a combination of CT scanning, endoscopic pancreatograms and endoscopic ultrasonography.Results: Twenty six (21%) patients had low faecal elastase.Of these, 5 were confirmed radiologically to have chronic pancreatitis.All 5 patients were shown to have abnormally high faecal calprotectin levels (90-534 µg/g).14 patients had suspected pancreatic insuYciency in the absence of other causative pathology.13 (93%) of these patients had elevated faecal calprotectin (73-799 µg/g).7 patients with low faecal elastase and 'watery' faecal samples were subsequently shown to have probably normal pancreatic function and an alternative explanation for symptoms (adenoma, Clostridial colitis, small bowel bacterial overgrowth, diverticular disease).Of these patients, 2 (29%) had abnormally high faecal calprotectin (176 µg/g=adenoma, 2670 µg/g=C.diVcolitis) (table 1). Conclusion:Pancreatic insuYciency may be associated with high faecal calprotectin in the absence of neoplastic or inflammatory intestinal disease.Low faecal elastase may also be associated with watery diarrhoea secondary to inflammatory intestinal disease, itself associated with an elevated faecal calprotectin concentration.
The Early Treatment of War Wounds
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Primary Sjögren's Syndrome After Infectious Mononucleosis
Authors: Stephen C. Pflugfelder
Journal: JAMA (1987)

<h3>To the Editor.—</h3> Primary Sjögren's syndrome is an immune disorder consisting of keratoconjunctivitis sicca and dry mucosal surfaces without an associated connective-tissue disorder.<sup>1</sup>This disease has characteristic autoantibodies, HLA association, and glandular histopathology.<sup>2-4</sup>We have examined two patients with primary Sjögren's syndrome occurring after infectious mononucleosis. <h3>Report of Cases.—Case 1.—</h3> A 5-year-old girl had parotid gland swelling, fever, and pharyngitis. Her white blood cell count was 9200/mm<sup>3</sup>(9.2×10<sup>9</sup>/L), with 7% (0.07) atypical lymphocytes. Epstein-Barr virus (EBV) titers one month after onset were as follows: viral capsit antigen (VCA) IgM, 1:40; VCA IgG, 1:320; and Epstein-Barr virus— associated nuclear antigen, 1:128. The serum IgG level was seven times normal and circulating immune complexes were present. Over the next two months, she was noted to have no tears when she cried. A Schirmer's test revealed 3 mm of wetting; 50% of the interpalpebral zone stained
The Scalp-Vein Needle
Authors: Kent Crossley
Journal: JAMA (1972)

The frequency of complications accompanying the use of the scalp-vein needle was evaluated in a prospective study of 219 needle insertions in 142 medical and pediatric patients. Significant local infection occurred in 4.2% of cases. Reactions at the venipuncture site were noted in 13.7% of the needle insertions and were usually associated with the administration of certain antibiotics. There was no evident correlation between the duration of needle use and the occurrence of local reaction or infection. In view of the risk of infection and sepsis that accompanies the use of polyethylene catheters, it is suggested that the scalp-vein needle offers an acceptable alternative to these devices.
A Text-Book of Inorganic Pharmaceutical Chemistry for Students of Pharmacy and Pharmacists.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Occupational and Environmental Medicine
Authors: Arthur L. Frank
Journal: JAMA (1992)

The past year was remarkable for two occurrences in the field of occupational and environmental medicine. The first is the role that preventive medicine, in its occupational and environmental aspects, played in protecting the health of US forces participating in Operation Desert Storm in the Middle East. Because of preventive actions taken in relation to the ambient working environment, and for the important issues of supplying necessary water and controlling infectious diseases, the half million troops participating in Operation Desert Storm experienced a remarkably low incidence of preventable illness traceable to infectious causes or dehydration. The insistence on proper fluid intake, coupled with infection control at the "worksite," led to a low casualty rate among troops. A major source of morbidity and mortality involved traditional workplace problems such as injuries, including motor vehicle accidents. While clearly nontraditional, an outstanding contribution was made to the overall effort by those who had
Ten Years of Operative Surgery in the Provinces
Authors: A. Prichard
Journal: BMJ (1861)

CASE CIXXXVI.M., aged 45, had been growing blind for nearly six years, but he had only given up work a fortnight before I saw bim.He had so sunken an eye and so overhanging a brow that it was difficult to operate.I nmade a puncture in the cornea of the right eye, and finished the section with the convex knife and scissars.He had an excellent recovery, and went away with a circular pupils and good sight.About a year afterwards, he came up to have the other eye done.I therefore extracted the left lens, and he re- covered speedily, and both his pupils were round and active.CASE CLXXXVII.M., aged about 60.I operated first on the right eye with an upper section, and extracted the lens easily; and then, also by an upper section, I ope- rated on the left eye.On the twelfth day after the ope- ration, he could see the time by my watch without a glass.He went home with circular pupils and excellent sight in eaclh eye.CASE CLXXXVIII.M., aged 67, was operated on six years before in the right eye, and recovered his sight for awhile, but it gradually was lost.I made the upper sectidn in the left eye, standing in front; and removed the lens easily.He recovered good sight, and was able to work.CASE CLXXXIX.M., aged 71.The right eye had been unsuccessfully operated on before.I made the lower section in the left eye; buit, immediately on its comple- tion, the lens and some vitreous humour started out upon his cheek.He had excessive spasmodic contrac- tion of his orbicularis palpebrarumn.Went home with im- proved siglht.CASE CxC.F., aged 70.Deeply sunken eyes and prominent brows.I operated on both eyes, making the lower section in the left eye, and upper section in the right.She recovered, with very good sight in the left eye; but in. the right it was Inot so clear.
Presence of Hepatitis B Surface Antigen Before Primary Hepatocellular Carcinoma
Authors: Abraham Nomura
Journal: JAMA (1982)

In a study of 7,498 men of Japanese ancestry in Hawaii, 18 incident cases of primary hepatocellular carcinoma were identified after a follow-up period of 13 years. Sixteen of the 18 patients had stored serum specimens available for analysis. Ten of the 16 had positive serum test results for hepatitis B surface antigen in their original specimens. None of 48 matched control subjects, whose stored serum specimens were also analyzed, had similar positive test results. This finding indicates that hepatitis B surface antigenemia preceded primary hepatocellular carcinoma in many patients. (<i>JAMA</i>1982;247:2247-2249)
What Is Adequate and Appropriate Pain Treatment?
Authors: Dan Murphy
Journal: JAMA (1996)

<h3>To the Editor.</h3> —In my work as a medical director of a methadone clinic I see how the city streets are flooded with pharmaceutical opiates. Addicts use them in times when heroin is scarce and may begin their addiction taking pharmaceuticals for one reason or another. Physicians, it goes without saying, are easily inveigled. It is a gross oversimplification for physicians to think only as Dr Hill<sup>1</sup>would advise, when patients demand adequate pain treatment for any and all types of pain. It is extremely difficult to decide exactly when and what amount of opiates should be used in each individual case, and even then appropriate caution must be exercised to minimize the disastrous results that can come with diversion and misuse of these medications.
Control of Cotton Dust Exposure
Authors: David C. Christiani
Journal: JAMA (1983)

<h3>To the Editor.—</h3> In the March 19 issue ofThe Journal(1982;247:1602), Holness and co-workers document changes in body temperature, WBC count, and ventilatory capacity in a healthy nonatopic woman exposed to cotton dust for six hours. The acute symptoms of fever, cough, chills, and malaise occurring in persons unaccustomed to cotton dust has been called "mill fever" since the 1940s and has been assumed to be unrelated to byssinosis even though the exact relationship between the two conditions remains inadequately studied. The authors suggest that mill fever and byssinosis may both be points on a continuous spectrum of cotton dust— induced effects. I agree with the authors that further study on the relationship between mill fever and byssinosis is necessary. However, I do not agree with the authors' recommendation for the use of respirators<i>alone</i>in controlling cotton dust disease. The most important method for control of cotton dust-induced
INACTIVATED MEASLES VACCINE
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The British Society of Gastroenterology
Authors: Barbara Smith, ; Mcclelland, Sheila Misiewicz, P Waller, J Anthony, M Gummer, M Marsh, J Swift, E Williams, J Ritchie, S Truelove, G Ardran
Journal: Gut (1968)

Achalasia of the cardia is associated with degeneration of the myenteric nervous plexus, but doubt exists whether the cardiac sphincter itself is denervated.1,2Earlier in vitro observations on human oesophageal muscle2 need to be interpreted in terms of ox-and ,-adrenergic receptors.