tbuckley/cabot-search huggingface dataset:
New England Journal of Medicine,
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
F-18 FDG PET-CT in a Rare Case of Bartholin's Gland Undifferentiated Carcinoma Managed With Chemoradiation and Interstitial Brachytherapy
Authors: Alessio Imperiale, Steve Heymann, Marcelo Clariá, Sébastien Cimarelli, Dorra Ben Sellem, Christian Goetz, Alina Onea, Cyrille Blondet, André Constantinesco
Journal: Clinical Nuclear Medicine (2007)

Prognosis of patients with Bartholin's gland carcinoma (BGC) is strictly related to the nodal stage at diagnosis. Thus, it is crucial to perform reliable staging for optimal treatment planning. In spite of wide clinical utilization of F-18 FDG PET in oncological routine, its role in vulvar malignancies is not completely defined. To keep organs and preserve anal and ureteral function, a patient with advanced undifferentiated BGC (FIGO IV-A) received 50 Gy to the whole pelvis, whole vagina and bilateral inguinal lymph nodes with concomitant chemotherapy, followed by interstitial brachytherapy. F-18 FDG PET-CT was performed at staging and after treatment completion. Complete regression of the initial metabolic abnormalities was shown on posttreatment images, confirming the efficacy of the adopted conservative approach. F-18 FDG PET-CT imaging could have a role in staging and assessing treatment efficacy in aggressive BGC.
Massage and Therapeutic Exercise.
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Production and Handling of Clean Milk.
Journal: JAMA (1910)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Indwelling Peritoneal (Tenckhoff) Dialysis Catheter
Authors: Tom E. Brewer
Journal: JAMA (1972)

The temporary Tenckhoff catheter has been utilized for intermittent peritoneal dialysis in 24 patients for periods from 1 to 14 months. Control of uremia has been comparable to our past experience with the repeated trocar puncture method. Although infection remains the most significant problem, it is avoidable by strict attention to sterile dialysis procedure and careful education of the patients concerning the daily care of their catheter and appreciation of its importance. The risk of infection under these circumstances is comparable to that of external arteriovenous shunts in hemodialysis. Our experience with the temporary Tenckhoff catheter warrants the conclusion that this catheter can be safely utilized and that peritoneal dialysis is an acceptable alternative or adjunct to hemodialysis.
Should Donor Blood Be Screened for Elevated Alanine Aminotransferase Levels?
Authors: Marc D. Silverstein
Journal: JAMA (1984)

We examined the cost-effectiveness of alanine aminotransferase (ALT) screening of donor blood to prevent non-A, non-B posttransfusion hepatitis. Based on estimated costs of ALT screening, blood replacement, and medical evaluation of donors with high ALT levels, we concluded that screening at an ALT level of 45 IU would cost $3.82 per unit. In a population requiring an average of 3.7 units per transfusion, one case of hepatitis would be prevented for every 115 units screened, resulting in a cost of $439 per case prevented. With an estimated direct medical cost of $1,181 per case of non-A, non-B hepatitis, expected net savings for each case prevented would be $742. Screening at other ALT thresholds would be less cost-saving. Sensitivity analyses indicate that screening would be cost-saving for a wide range of cost estimates and number of units per transfusion. Alanine aminotransferase screening is warranted until more sensitive and specific screening tests for transmissibility of non-A, non-B hepatitis become available. (<i>JAMA</i>1984;252:2839-2845)
Blood-Pressure, Its Clinical Applications.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Combination of IFN-<b>α</b> and 5-Fluorouracil Induces Apoptosis through IFN-α/β Receptor in Human Hepatocellular Carcinoma Cells
Authors: Motoi Kondo, Hiroaki Nagano, Hiroshi Wada, Bazarragchaa Damdinsuren, Hirofumi Yamamoto, Nobuaki Hiraoka, Hidetoshi Eguchi, Atsushi Miyamoto, Tameyoshi Yamamoto, Hideo Ota, Masato Nakamura, Shigeru Marubashi, Keizo Dono, Koji Umeshita, Shoji Nakamori, Masato Sakon, Morito Monden
Journal: Clinical Cancer Research (2005)

Abstract Purpose: Several studies showed the effectiveness of combination therapy with IFN-α and 5-fluorouracil (5-FU) for advanced hepatocellular carcinoma. However, only little is known about the underlying mechanism of combination therapy. In the present study, we examined whether apoptosis through IFN-α/β receptor (IFN-α/βR) was associated with the effects of combination therapy. Experimental Design: HuH7, PLC/PRF/5, HLE, and HLF were treated with IFN- (500 units/mL), 5-FU (0.5 μg/mL), or their combination for 10 days. In addition, IFN-α/βR gene transfer with combination therapy was done. Results: Ten-day treatment by combination therapy resulted in &amp;gt;80% cell growth inhibition. Terminal deoxynucleotidyl transferase–mediated dUTP nick end labeling analysis showed synergistic effects for combination therapy on PLC/PRF/5, HLE, and HLF. Concordant results were obtained with DNA fragmentation. Moreover, there was an evidence showing that changes in the expression of Bcl-2 family lead to apoptosis. On the other hand, the expression of IFN-α/βR and up-regulation of α-phospho–signal transducer and activator of transcription 1, IFN regulatory factor-1 by combination therapy were observed in all cell lines. Furthermore, IFN-α/type 2 IFN receptor long form–transfected HuH7 cells treated with combination therapy showed strong DNA fragmentation compared with nontransfected or transfected with IFN-α- and 5-FU-treated HuH7. Conclusions: Our results showed that combination of IFN-α plus 5-FU strongly induced cell growth inhibition of human hepatocellular carcinoma cells and indicated that oneof the direct mechanisms of combination therapy may in part be attributable to alterations in induction of apoptosis through IFN-α/βR.
Medical schools in the United States
Journal: JAMA (1977)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Anatomy of the Human Orbit and Accessory Organs of Vision.
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Measles Outbreak--Netherlands, April 1999-January 2000
Journal: JAMA (2000)

On June 21, 1999, a cluster of five cases of measles was reported among the 390 students attending a religion-affiliated elementary school in The Netherlands. Persons belonging to this religious denomination routinely do not accept vaccination. Municipal health services (MHSs) investigated and found 160 suspected measles cases among children attending the school. By February 4, 2000, 2961 measles cases, including three measles-related deaths, had been reported by 35 MHSs to the national registry. This report summarizes the investigation of the measles outbreak in The Netherlands, which indicated that measles can be a severe disease among unvaccinated populations in The Netherlands.
An ethical dilemma: Medical errors and medical culture An error of omission Commentary: Learning to love mistakes Commentary: Doctors are obliged to be honest with their patients Commentary: A climate of secrecy undermines public trust
Authors: P. A Singer
Journal: BMJ (2001)

# Medical errors and medical culture {#article-title-2} A junior doctor fails to read an electrocardiogram that has been ordered and the patient dies, undiagnosed and in pain, from a myocardial infarction. We asked a professor of medical ethics, an expert in medical errors, and two clinicians to comment on the ethical implications of covering up the mistake. # An error of omission {#article-title-3} The patient, an elderly lady, was blind and deaf without speech. She had been brought in as an emergency case, clutching her abdomen and moaning. She had been like that for a couple of hours and had also vomited a few times. On examination she had some epigastric tenderness, her heart and lungs were normal, and her blood pressure was slightly low. Routine investigations were ordered; a drip was set up; and the team moved on. On the next round the patient was still in severe pain. Nothing new had turned up. Her serum haemoglobin concentration, blood biochemistry, and chest and abdominal radiographs were normal. We hesitated about whether to provide pain relief. Antispasmodic drugs had been ineffective. An ultrasound scan ruled out problems with the patient's gallbladder. Endoscopy took another day to organise and produced negative results. The patient's pain and sickness continued. On the fifth day she died: the causes undiagnosed, her suffering unrelieved. As house officer on the ward I had to prepare a case summary. Fishing in the pack of x ray films for the reports I caught the long strip of an electrocardiogram. It bore the date of admission. I had asked a nurse to do it as part of the routine work up but had not remembered to check the results. The textbook signs of an extensive acute myocardial infarction were plain even to my untrained eye. I took the tracing to the senior consultant's office. He cast a glance over it then stared … Correspondence to: S Fazel
Purine and Pyrimidine Hodgkin's Disease
Journal: JNCI Journal of the National Cancer Institute (1972)

The urinary excretion of purines and pyrimidines by 33 patients with Hodgkin's disease was correlated with clinical and histologic features. The results showed a positive relationship between high urinary levels of pseudouridine and features with a poor prognostic implication, i.e., constitutional symptoms and the predominance of atypical histiocytes and Reed-Sternberg cells in biopsy specimens. The atypical histiocytes may be responsible for the fever of noninfectious etiology in some patients with Hodgkin' s disease.
A Text-Book of the Theory and Practice of Medicine by American Teachers.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Place of Version in Obstetrics.
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Differentiation by Immunoferritin of Herpes Simplex Virion Antigens With the Use of Rabbit 7S and 19S Antibodies From Early (7-Day) and Late (7-Week) Immune Sera
Journal: JNCI Journal of the National Cancer Institute (1971)

Baby hamster kidney (BHK-21) cells infected with herpes simplex virus (HSV) were examined before and during viral morphogenesis with ferritin-conjugated early (7-day) and late (7-week) 7S and 19S rabbit anti-HSV antibodies. These 4 antibody fractions, reported elsewhere to differ in their neutralizing properties against the isologous virus and against cross-reacting herpesvirus strains, were found to differ in their reactivity with HSV virion-associated antigens. Before virus appeared, the antigens reactive with early antibodies (7S and 19S) were found in the cytoplasm and the nucleus, whereas most antigens reactive with late antibodies (7S and 19S) were restricted to the nucleus. Evidence obtained suggests that cytoplasmic antigens enter the nucleus through the nuclear pores. At early stages of infection, disrupted nucleoli reacted with early 7S antibodies. Viral cores of low density reacted with early 7S antibodies, whereas viral capsids reacted with both early 19S and late 7S antibodies. Envelopment of capsids occurred at the nuclear and tubular cytoplasmic membranes. Initial stages of envelopment were characterized by the appearance of “early” membrane-associated antigens reactive with early 7S and late 19S antibodies. As the membrane became altered structurally so that it resembled the envelope of the virus, the “early” membrane-associated antigens were no longer detectable, and antigens reactive with early 19S and late 7S antibodies appeared.
A-Like Blood Group Antigen in Gastric Cancer Cells of Patients in Blood Groups O or B&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;
Journal: JNCI Journal of the National Cancer Institute (1970)

Several samples of mucosa were prepared systematically from surgically removed stomachs of patients with peptic ulcer or gastric cancer. The appearance of A and B blood group antigens in the samples was studied immunohistologically. The material included patients belonging to the A, B, and O blood groups. The hetero-anti-A and B immune sera prepared for the present purpose were specific in serological tests, and the immunohistological localization in normal gastric mucosa demonstrated the perfect blood group specificity of the above immune sera. In four patients with gastric cancer—three in blood group B and one in O—an A-like antigen was sometimes demonstrated in tumor cells of three of them but, in the fourth, most of the tumor cells contained this antigen. The same antigen was found occasionally in areas near the border of the tumor in superficial mucous or foveolar cells. The “neo”-A antigen could not be distinguished by conventional serological means from normal A antigen. Since biosynthesis of the A antigen is genetically controlled, somatic mutation possibly is the basis for this neo-antigen. Cell clones whose transplantation antigens differ apparently can be in the same tumor.
The Anatomy of the Human Orbit and Accessory Organs of Vision.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal