Abstract 752: Increasing cancer patient acceptance of tobacco cessation by an innovative patient-centric personal pathway to success (PPS) program
Authors: Cary A. Presant, Kimlin Ashing, Sophia Yeung, Jonjon Macalintal, Brenda Gascon, Alexis Stewart, Argiela Sandoval, Mary Cianfrocca, Ravi Salgia, Dan Raz, Loretta Erhunmwunsee, Janet Cronkhite, Khristie Davy, Yuman Fong, Steven Rosen
Journal: Cancer Research (2023)

Abstract Background: Participation in tobacco cessation programs by cancer patients (pts) is a challenge. We developed a cessation program Personal Pathway to Success (PPS) to increase diverse pts’ uptake of cessation services. Methods: City of Hope (COH) tobacco cessation program requires a tobacco use survey, and a Societal Determinants of Health Scale. 34 cessation services were offered to pts in PPS. All pts received 3 PPS services: motivational interview (MI) with a tobacco treatment specialist (TTS), a cessation educational video and brochure. Pts were classified as PPS+ (enhanced intervention) if they accepted supportive counseling by a TTS, and created their personal quit plan from PPS services. But pts classified as PPS- did not accept other services. PPS+ could add or delete services at any time. PPS- received monthly invitations to PPS+ by a TTS at each clinical visit. Early-Quit was defined as self-reported abstinence at 3 months (3monQuit). We tested this program in the preoperative clinic. Results were compared using univariate statistics. Study data collection was 9/2021 to 9/2022. Results: 55 pts were eligible. 19 (37%) pts were Caucasian (WH) while 32 (63%) pts were minority (MIN: Asian 5%, Hispanic 24%, Black 5%, and Middle Eastern [ME] 20%). Of the 55, 26 chose PPS+ (47%), while 29 chose PPS-. Patients &amp;gt;65 y.o. were more likely to choose PPS+ (70%) versus ≤65 (29%, p=0.003). 8 of 19 (42%) WH pts, 3 of 5 (60%) Black pts, 9 of 12 (75%) Hispanic pts and 3 of 10 (30%) of ME pts, became PPS+. Mean number of PPS services used tended higher in WH (16.5) versus MIN pts (12.4, p=0.11). Although non-significant, 3monQuit tended greater in MIN pts 37% compared to WH 26% (p=0.38). Overall, 3monQuit was achieved by 38% of PPS+, and 28% of PPS- pts (p=0.49). In PPS-, 0% of WH pts were 3monQuit versus 53% of MIN pts were 3monQuit (p=0.001). Among PPS+, 63% of WH pts were 3monQuit, versus 29% of MIN pts (p=0.12). Of PPS+ who did not quit, 71% reduced tobacco use. 3monQuit was not associated with age, gender or receipt of cessation support medications. Conclusions: In this initial pilot study, our patient-centric PPS intervention enhanced pts’ uptake of cessation. Overall, our PPS+ intervention increased cessation reach and 3monQuit. PPS+ was required to achieve abstinence in WH pts. But PPS- intervention (MI, video, brochure only) resulted in 3monQuit even without counseling among MIN pts only. Our findings suggest a more favorable cost-benefit outcome of tobacco cessation in MIN populations with Min pts requiring minimal intervention to achieve 41% abstinence. Thus, medical clinics even in low resource settings ought to increase offering tobacco cessation especially to MIN pts who are at greatest risk for tobacco related diseases, and who may benefit the most with the least amount of intervention. Confirmation of these results with a larger sample in other clinical settings is ongoing. Citation Format: Cary A. Presant, Kimlin Ashing, Sophia Yeung, Jonjon Macalintal, Brenda Gascon, Alexis Stewart, Argiela Sandoval, Mary Cianfrocca, Ravi Salgia, Dan Raz, Loretta Erhunmwunsee, Janet Cronkhite, Khristie Davy, Yuman Fong, Steven Rosen. Increasing cancer patient acceptance of tobacco cessation by an innovative patient-centric personal pathway to success (PPS) program [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 752.