tbuckley/cabot-search huggingface dataset:
Mammographic screening in asymptomatic women aged 40 years and older. Council on Scientific Affairs
Journal: JAMA (1989)

Currently, age-specific recommendations for screening mammograms in asymptomatic women that have been developed by professional, voluntary, and governmental organizations differ. While there is strong epidemiologic evidence that mammographic screening in asymptomatic women aged 50 years or older reduces breast cancer mortality, the evidence for mortality reduction is not as clear for women aged 40 to 49 years. However, as described in this report, findings of further mortality and survival follow-up of subjects in earlier studies, as well as observations from more recent studies, suggest reductions in mortality and better survival in younger women as well. While mammography is currently the most effective method for detecting early breast cancers, some breast cancers may develop during the intervals between screening mammograms. The costs of mammographic screening also require consideration in the process of making national screening recommendations.
Rheumatic Heart Disease Epidemiology
Authors: William E. Morton
Journal: JAMA (1967)

During an evaluation of heart-disease screening methods among 17,366 Denver parochial school children, rheumatic heart disease (RHD) epidemiologic data were collected. The RHD prevalence rate was 1.7 cases per 1,000 enrolled. A history of rheumatic fever was elicited from 12.4% of the population and from 44.8% of the RHD cases. Prevalence rates of RHD and of rheumatic fever history were higher among older students and among those from lower socioeconomic circumstances. The excess RHD prevalence at the bottom of the socioeconomic scale was due largely to cases of RHD without a history of clinical rheumatic fever. Ethnic differences in RHD prevalence were believed to be explained by differences in their socioeconomic distributions, although there were insufficient data to satisfactorily document this hypothesis. RHD prevalence in students has apparently diminished during the past 40 years.
Physician reporting of sexual abuse of children
Authors: J. James
Journal: JAMA (1978)

SEXUAL abuse of children is a growing concern nationally. Whereas incest, rape, and molestation of children were considered almost nonexistent a decade ago, current public alarm has resulted in communities throughout the country developing hot lines, treatment programs, and educational programs for victims and their families. In response to the existence of these services and improved laws, numerous sexual abuse cases are beginning to surface. Sgroi<sup>1</sup>states that the number of reported cases in Connecticut doubled between 1973 and 1974 to a total of 172. Similarly, in Santa Clara, Calif, the number of treatment cases has grown from 36 in 1971 to 180 in 1974.<sup>2</sup>From 1974 to 1976, the number of child sexual abuse cases seen annually at the Sexual Assault Center in Seattle has almost doubled and has increased in proportion from 41% to 53% of their total clientele. The reports from the two treatment units
Feedback can improve doctors' record keeping---a bit
Journal: BMJ (1999)

Women should be advised to allow adequate time after stillbirth before next pregnancy Some clinicians have argued that women need time to recover emotionally after stillbirth and before beginning the next pregnancy, but without systematic evidence to support this.In a cohort study (p 1721) Hughes et al found that in the pregnancy after stillbirth women showed significantly higher depression and state anxiety in the third trimester than control women, and that the difference was accounted for by women who conceived within 12 months after the stillbirth.These women were also more depressed 1 year after the next birth.Women who conceived more that 12 months after stillbirth were similar to their controls at all points.Women may need a year to recover after stillbirth-or perhaps those who become pregnant quickly are more vulnerable to depression and anxiety.
Adverse Effect on Bone Marrow Protection of Prechemotherapy Granulocyte Colony-Stimulating Factor Support
Authors: Ronald de Wit, Jaap Verweij, Marijke Bontenbal, Wim H. J. Kruit, Caroline Seynaeve, Paul I. M. Schmitz, Gerrit Stoter
Journal: JNCI Journal of the National Cancer Institute (1996)

Increased proliferation of endogenous bone marrow progenitor cells in response to the administration of hematopoietic growth factors, followed by reduced cell cycling or entrance of the cells into a quiescent state upon withdrawal of the growth factors, may have clinically relevant effects on the tolerance of the hematopoietic system to subsequent myelotoxic treatments. We investigated the ability of granulocyte colony-stimulating factor (G-CSF) to protect progenitor cells in the bone marrow of cancer patients from the toxic effects of subsequent treatments with chemotherapeutic agents. Thirty-six patients with histologically documented, locally advanced or metastatic breast cancer were randomly assigned to receive doxorubicin once every 3 weeks at a dose of 75 mg/m 2 and cyclophosphamide at a dose of 1000 mg/m 2 , with G-CSF administered either before and after chemotherapy (18 patients) or after chemotherapy only (18 patients). For prechemotherapy administration of G-CSF, recombinant human methionyl (r-met Hu) G-CSF was administered subcutaneously to patients twice per day for 5 days at a dose of 5 μg/kg, with the last dose given 48 hours before the start of chemotherapy. For postchemotherapy administration of G-CSF, r-met Hu G-CSF was administered subcutaneously to patients once per day for 7 days at a dose of 5 μg/kg, with the first dose given 24 hours after chemotherapy. The incidence or the duration of grade 4 neutropenia was not reduced in all patients by the use of prechemotherapy G-CSF; the incidence over all cycles of chemotherapy was 74% for patients treated with prechemotherapy and postchemotherapy G-CSF and 66% for patients treated with postchemotherapy G-CSF only (two-sided P , adjusted for dose =.21) and the median duration in both treatment arms was 3 days (two-sided P =.19). Unexpectedly, the incidence of grades 3 and 4 thrombocytopenia was much greater in patients who received prechemotherapy G-CSF compared with those who did not (54% versus 6%, respectively, over all chemotherapy cycles; two-sided P , adjusted for dose <.001). No difference in the decrease in hemoglobin level (adjusted for red blood cell transfusions) between patients in the two treatment arms was observed. No beneficial effects were associated with the administration of G-CSF to cancer patients prior to chemotherapy. The observation of more severe thrombocytopenia in patients treated with prechemotherapy G-CSF led us to conclude that the proliferation of progenitor cells was still increased 48 hours after the last dose of G-CSF and that the administration of chemotherapy at or within this time period actually worsens the toxic effects on bone marrow. This result has important ramifications for the design of clinical cancer treatment protocols, especially those that involve shortened intervals between cycles of chemotherapeutic agent administration.
Akusherstvo i Ginekologiia, Moscow
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Isolation of an Alpha Crystallin Antigen from Chick Iris
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Trimethoprim Resistance determined by R Factors
Authors: R. N. Gruneberg
Journal: BMJ (1972)

In any research study, researchers situate themselves, either explicitly or implicitly, within a variety of frameworks when studying phenomena. From a research perspective, the study will be more robust if these frameworks and the accompanying assumptions are compatible with each other; otherwise, the project may lack coherence. Ricoeur offers a methodological perspective—that is, an interpretive theory as reflected in <i>mimesis</i>, which is congruent with his ontological theory of self identity (<i>ipse</i>- and <i>idem</i>-identity). To illustrate Ricoeur’s frameworks when researching the self identities, I use examples from a research study in which I asked senior nursing students to explore their experience of becoming a nurse. I do not intend for this article to be a comprehensive research report, but I present it as an exemplar of how Ricoeur’s ideas can guide other researchers studying self identity. I labelled my study a narrative research project and assumed that becoming a nurse means developing a self identity as a nurse. While self identity is often framed in psychological terms, Ricoeur uses a philosophical perspective when exploring this concept. I conclude the paper by suggesting (a) that Ricoeur can guide any project in which researchers ask participants to describe “becoming” a person with illness, sickness or disease, and (b) that educators of healthcare professional students can improve the educative experience by purposefully considering how a student’s ontological self affects that student’s practice.
THE VALUE OF INDEXED CASE RECORDS
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
What are the optimal systemic treatments for men with metastatic, hormone-sensitive prostate cancer? A STOPCaP systematic review and network meta-analysis
Authors: C.L. Vale, D.J. Fisher, J. Carpenter, I.R. White, S. Burdett, N.W. Clarke, K. Fizazi, G. Gravis, N.D. James, M.D. Mason, M.K. Parmar, L.H. Rydzewska, C.J. Sweeney, M.R. Spears, M.R. Sydes, J.F. Tierney
Journal: Annals of Oncology (2017)
Treatment of Achalasia: Botulinum Toxin Injection vs. Pneumatic Balloon Dilation. A Prospective Study with Long-Term Follow-Up
Authors: H. D. Allescher, M. Storr, M. Seige, R. Gonzales-Donoso, R. Ott, P. Born, E. Frimberger, N. Weigert, A. Stier, M. Kurjak, T. Rösch, M. Classen
Journal: Endoscopy (2004)

Correction to:Treatment of Achalasia: Botulinum Toxin Injection vs. Pneumatic Balloon Dilation. A Prospective Study with Long-Term Follow-UpEndoscopy 2001; 33(12): 1007-1017DOI: 10.1055/s-2001-18935
Determination of right ventricular wall thickness by echocardiogram
Authors: R. Prakash
Journal: JAMA (1978)

Right ventricular wall-thickness measurements were performed by echocardiography and at necropsy in 25 patients. Correlations were made and found to be good in all subjects (<i>r</i>=.82). The echocardiographic technique was successful in separating nine patients with right ventricular hypertrophy from 16 patients without right ventricular hypertrophy at necropsy. The diagnosis of right ventricular hypertrophy by ECG correlated poorly with necropsy and echocardiographic findings. Right ventricular wall thickness can be accurately measured by echocardiography. (<i>JAMA</i>239:638-640, 1978)
Announcements
Authors: John B. Martin, R.O. Pihl, W.D. TenHouten, K.D. Hoppe, J.E. Bogen, D.O. Walter, Rishun Sinzato, Osamu Fukino, Hajime Tamai, Hitoshi Isizu, Tetsuya Nakagawa, Manfred Beutel, H.M. van der Ploeg, E.T. van Buuren, P. van Brummelen, Giovanni A. Fava, Thomas N. Wise, George Molnar, Maria Zielezny, Han Kutz, Jane Leserman, Claudia Dorrington, Catherine H. Morrison, Joan Z. Borysenko, Herbert Benson, Yujiro Ikemi
Journal: Psychotherapy and Psychosomatics (1985)
Frivolous claims
Authors: A. R. Holder
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PAMPHLEIS RECEIVED
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Al Pie de la Cuna.
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
HAVANA'S HEALTHFULNESS.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ex vivo transduced liver progenitor cells as a platform for gene therapy in mice
Authors: Sihong Song, Rafal P. Witek, Yuanqing Lu, Young-Kook Choi, Donghang Zheng, Marda Jorgensen, Chengwen Li, Terence R. Flotte, Byron E. Petersen
Journal: Hepatology (2004)

Allogeneic stem cell-based transplants may be limited by allograft rejection, as is seen with conventional organ transplantation. One way to avert such a response is to use autologous stem cells, but that may carry the risk of recurrence of the original disease, particularly in the context of a genetic defect. We investigated the potential for gene modification of autologous stem cells to avoid both problems, using recombinant adenoassociated virus vector expressing human α1-antitrypsin in murine liver progenitor cells. We showed that recombinant adenoassociated virus 1 was the most efficient vector for liver progenitor cell transduction among five different serotypes of recombinant adenoassociated virus vectors. Ex vivo infected green fluorescent protein-positive liver progenitor cells from C57BL/6 mice with recombinant adenoassociated virus 1-vector-expressing human α1 antitrypsin were transplanted into the liver of monocrotaline-treated and partial-hepatectomized C57BL/6 recipients. Using green fluorescent protein as a donor marker, we were able to determine that at 18 weeks after transplantation, approximately 40% to 50% of the regenerated liver was green fluorescent protein positive. In addition, transgene expression (serum human α1-antitrypsin) was sustained for the length of the study (18 weeks after transplantation). Immunostaining revealed approximately 5% to 10% of repopulating liver cells expressing human α1-antitrypsin. In conclusion, this study demonstrated the feasibility of long-term engraftment and stability of transgene expression form genetically modified liver progenitor cells with a recombinant adenoassociated virus vector and implies a novel approach to gene therapy for treatment of liver diseases, such as α1-antitrypsin deficiency. (Hepatology 2004;40:918–924).
ROENTGENOGRAPHY OF COLLES' FRACTURE
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal