tbuckley/cabot-search huggingface dataset:
Update on the genetic effects of ionizing radiation
Authors: J. V. Neel
Journal: JAMA (1991)

The genetic implications of human exposures to radiation continue to be very much on the public mind. Interest in the issue was greatly stimulated by the report of Gardner and associates<sup>1</sup>last year. In an effort to understand the excess of childhood leukemia and lymphoma reported in the vicinity of the Sellafield nuclear plant in the West Cumbria district of the United Kingdom, these investigators conducted a case-control study for environmental associations with these diseases. The study identified 52 cases of leukemia, 22 of non-Hodgkin's lymphoma, and 23 of Hodgkin's disease, all occurring under 25 years of age. For each case, up to eight controls were used. Because many of the tests for associations are overlapping, it is difficult to deduce how many independent statistical tests were performed, but it appears to be at least 70. The most significant finding was that the fathers of children who developed leukemia
Table of contents
Authors: Andreas Wollenberg, Stefanie Wetzel, Walter Burgdorf, Jürgen Haas, Rebecca Gruchalla, James Jones, Charles Hackett, You Cho, So-Yeon Park, Chang-Keun Lee, Bin Yoo, Hee-Bom Moon, Claudia Gore, G Peterson, Patricia Kissen, Bridget Simpson, Lesley Lowe, Ashley Woodcock, Adnan Custovic
Journal: Journal of Allergy and Clinical Immunology (2003)
Just a little bit more about drug lag
Authors: D. Kennedy
Journal: JAMA (1978)

IN AN article in the May 12, 1978, issue of<i>JAMA</i>, William Wardell, MD, PhD, delivered a lengthy rebuttal to an earlier article of mine on the so-called "drug lag." Because both sides of the argument have been stated in fairly extended form, I am satisfied to leave to the fair-minded reader the judgment of those issues in which we genuinely differ. I do, however, want to make a few points in an effort to limit the controversy to those areas in which real differences do exist. Dr Wardell begins his article with an extended series of quotations from articles, testimony, and other sources for the purpose of showing inconsistencies between my own stated views and those of my predecessors and colleagues at the Food and Drug Administration. These quotations and the speeches of mine that Dr Wardell cites should be compared carefully by anybody who thinks that there is really
The British Medical Association: ITS CONSTITUTION AND GOVERNMENT: AN HISTORICAL SURVEY
Authors: J. C. McVail
Journal: BMJ (1924)

MDIA JOR 9 nitrogen of the urine.Clinical commnents and dietary suggestions follow each section, and there are chapters on, diagnosis of impaired kidney function and the dietary control of disturbances of metabolism.Thelastchapter is on diabetes, and includes insulin treatment.The methods described are all standard ones, though some have been slightly modifled to meet the demands of the clinical labora- tory using relatively small quantities of blood.It is questionuble .whetherthose to whom this book is dedicated will have either the time or the inclination to perform these tests, but those who are disposed to undertake such work will find it convenient to have the methods collected into one handy book of small compass.Marriage and Syphilis: A Treatise on Euigenics,'0 by Dr. G. M. KATSAINo of' Boston, U.S.A., has been written from the point of view of the propagandist rather than that of the nyphilologist.The author believes that.syphilis, in spite of the work of public health departments, voluntary soGieties, and individual workers, has not yet received the attention that it merits, and in his book he makes a forcible, if some- 'What sentimental appeal to his readers.The sentence printed on the fly-leaf sums up his object: I If by this work of mine the procreation of even one syphilitic child is prevented my time, efforts, and expenses have not been in vain."'The TWeekly Telegraph Guide to Holiday Resorts,11 a deservedly popular annual which has now reached its twenty- ninth year, contains a brief description in alphabetical order of holiday resorts in England, the Channel Islands, Isle of Wight and Isle of Man, Wales, Scotland, and Ireland, with lists of hotels, boarding-houses, and lodgings.A few
Abstract P4-12-01: A New Resource To Accelerate Research into the Cause and Prevention of Breast Cancer: The Love/Avon Army of Women
Authors: Dr Love SM.
Journal: Cancer Research (2010)

Abstract Background: It is well established that there is a need for more research into the cause and prevention of breast cancer. While many studies are done in cell lines and laboratory animals, translation of findings to women often falters due to perceived difficulty in recruiting women for research. The Dr. Susan Love Research Foundation received a grant from the Avon Foundation to form the Love/Avon Army of Women (AOW); an online recruitment resource designed to partner women with the research community in an effort to accelerate breast cancer research. Methods: The AOW was launched in 2008 with the goal of recruiting one million women interested in participating in breast cancer research, and of encouraging researchers to submit studies for recruitment. Researchers interested in having the AOW recruit for their studies submit a proposal that will be reviewed by the AOW Scientific Advisory Committee, comprised of nominees from AACR and NBCC. If a study is accepted, a mass e-mail describing the study procedures and inclusion/exclusion criteria is sent to the entire AOW database. Women sign up at www.armyofwomen.org to join the AOW. Women aren't committing to participating in a particular study, but agree to receive AOW e-mails about breast cancer research studies. Women self select based on interest and study criteria, and undergoa secondary on-line screening before contact information is passed on to the researcher for the enrollment process. Results: Over 334,000 women have signed up, including survivors and healthy women, ranging from ages 18 to 100, representing all 50 US states and 47 countries. To date, the AOW has recruited for 31 studies, both regional and national, that vary from biomarker and circadian rhythm research to psycho-social and quality of life studies. With over 41,000 AOW members having participated in the research process, this method of recruitment has been found to be effective and efficient. The diversity of the AOW members has proved beneficial for many studies such as those needing to enroll African American women, women of varying sexual orientations, or young survivors. Many studies were closed to enrollment within the first 48 hours after accruing all subjects while others were very quickly over-enrolled by 5-10%. This overwhelming response has led many researchers to seek additional funding to increase their statistical significance and accommodate all eligible subjects. Conclusions: The Love/Avon Army of Women is a novel resource for scientists to accelerate accrual, expand the number and diversity of their subject population and to obtain exactly the type of specimens they need when they need it. This new partnership between women and scientists can revolutionize research and accelerate efforts to eradicate breast cancer. Citation Information: Cancer Res 2010;70(24 Suppl):Abstract nr P4-12-01.
Managing spinal cord compression and lung cancer.
Journal: BMJ (1991)

treated initially by aspiration,' but their conclusion that the "finding of no pleural leak should avoid unnecessary tube drainage and permit early dis- charge, whereas had these patients been treated with an intercostal drain from the outset their hospital stay would inevitably be prolonged" is clearly not sufficient justification to purchase a flame ioniser as they suggest.Few people would drain all these patients from the outset-a trial aspiration followed by repeat radiograph the next day if the lung re-expanded would be more usual.
Sweet Prince
Authors: Peter Blewett
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SI units
Authors: Patricia H. Field
Journal: JAMA (1985)

<h3>To the Editor.—</h3> You are to be commended for the Oct 12, 1984,<i>JAMA</i>theme issue on alcohol and other drugs, and for the ten recommendations in your editorial.<sup>1</sup> However, my pleasure in reading the issue was jarred by confusion about the reporting units for ethanol concentrations. Page 1886, column 1, paragraph 1, indicates that the "mean blood alcohol concentration . . . was 0.20 ± 0.08 mg/dL, or twice the level of legal intoxication (0.10 mg/dL) in Wisconsin." In fact, the ethanol level, which is illegal per se for Wisconsin drivers, is 0.10% wt, or 100 mg/dL. No doubt the mean blood alcohol concentration in the study was 0.20% wt, or 200 mg/dL. On page 1837, 0.04 mg/dL is referred to as a level that " 'has been shown to bring about measureable diminution of attention and skills,' " a statement that would be more accurate for 40 mg/dL, or 0.04% wt.
Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape
Authors: Meenakshi Hegde, Malini Mukherjee, Zakaria Grada, Antonella Pignata, Daniel Landi, Shoba A. Navai, Amanda Wakefield, Kristen Fousek, Kevin Bielamowicz, Kevin K.H. Chow, Vita S. Brawley, Tiara T. Byrd, Simone Krebs, Stephen Gottschalk, Winfried S. Wels, Matthew L. Baker, Gianpietro Dotti, Maksim Mamonkin, Malcolm K. Brenner, Jordan S. Orange, Nabil Ahmed
Journal: Journal of Clinical Investigation (2021)
Joint British recommendations on prevention of coronary heart disease in clinical practice: summary
Journal: BMJ (2001)

Patients with CHD or other major atherosclerotic diseaseFor all patients with coronary heart disease (angina, myocardial infarction) or other major atherosclerotic disease, every effort should be made to achieve the lifestyle, risk factor, and therapeutic targets given in the table.The care of coronary patients should embrace all aspects of cardiac prevention and rehabilitation. Priorities for CHD prevention in clinical practice(1) (a) Patients with established coronary heart disease (b) Patients with other major atherosclerotic disease (2) Patients with hypertension, dyslipidaemia, diabetes mellitus, family history of premature CHD, or a combination of these risk factors, which puts them at high risk of developing CHD or other atherosclerotic disease.Patients with diabetes melitus are at particularly high risk of CHD Lifestyle, risk factor, and therapeutic targets for prevention of coronary heart disease (CHD) in patients with established CHD or other atherosclerotic disease and in healthy people at high risk of developing this disease Patients with CHD or other atherosclerotic disease People without overt CHD or atherosclerotic disease at high risk (absolute CHD risk>15% over 10 years) Lifestyle targets for all patientsStop smoking, make healthier food choices, increase aerobic exercise, and moderate alcohol consumption Body mass index <25 kg/m 2 is desirable, with no central obesity
THE "ALKALINITY" OF THE BLOOD.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review The New International Clinics: Original contributions, clinics and evaluated reviews of current advances in the medical arts . Edited by George Morris Piersol, M.D. Vol. III, New Series Three. 8°, cloth, 358 pp., with 87 figures, 17 tables, and 14 charts. Philadelphia: J. B. Lippincott Company, 1940. $3.00.
Journal: New England Journal of Medicine (1941)
Human insulin crystals
Authors: D. S. Schade
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Too little control over biological research, say the British
Journal: Annals of Oncology (1999)

went to companies serving as PR agencies for the ARC.Astonishingly, for many years only about onethird of the money was used to support research.However, as Mr Crozemarie said during the trial, "There was never a single remark made at any of the meetings of the bodies of the ARC which I attended," It appears that both managers and scientists were so impressed by Mr Crozemarie's natural authority that they never suspected what was going.However, as the distinguished French daily Le Monde put it (18 June 1999), "People who donated their money are still asking questions about how this could happen."The trial seems to have been unable to provide an answer.These events are probably the main reason why cancer charities are now having major difficulties in collecting the same amounts of money as during Mr Crozemarie's better days.
Where Do We Stand? Global Ecosystem Assessments Ask the Big Question
Authors: David J. Tenenbaum
Journal: Environmental Health Perspectives (2001)

W here Do We Stand?H ow healthy are the earth's ecosystems?Will they continue to provide the food, water, shelter, and other necessities on which all life depends?These pressing questions have been receiving attention from two international collaborations: The Pilot Analysis of Global Ecosystems (PAGE) was completed in late 2000 and detailed in World Resources 2000-2001, the biennial report of the World Resources Institute (WRI), and the upcoming Millennium Ecosystem Assessment (MEA) is due for completion in 2005.The degradation of ecosystems is literally ancient history.Desertification-an enduring ecosystem degradation-gets much of the blame for the decline of ancient civilizations in the Middle East.More recently, the severe soil erosion of the Dust Bowl in the U.S. Great Plains during the 1930s started with unsustainable farming practices and was exacerbated by drought.In total, according to a 2000 report by the United Nations Environment Programme (UNEP) titled An Assessment of Risks and Threats to Human Health Associated with the Degradation of Ecosystems, desertification is now damaging 30% of irrigated areas, 47% of rainfed land, and 73% of rangelands.Other examples of broad ecosystem degradation include the hypoxic "dead zones" in the Gulf of Mexico and other waters around the world, the disastrous decline of Black Sea fisheries due to the introduction of exotic species, and intensified flooding in Bangladesh and Central America caused partly by deforestation.These and other such alterations reflect global-scale changes caused by human activities, particularly climate change and stratospheric ozone depletion.Ecosystem assessments stand traditional environmental monitoring on its head by examining an entire ecosystem, such as a watershed, mountain range, or coastline, rather than, say, a tract of land or an industrial sector.No longer, says
Stability and Effectiveness of Chlorine Disinfectants in Water Distribution Systems
Authors: Vincent P. Olivieri, Michael C. Snead, Cornelius W. Kruse, Kazuyoshi Kawata
Journal: Environmental Health Perspectives (1986)

A test system for water distribution was used to evaluate the stability and effectiveness of three residual disinfectants--free chlorine, combined chlorine, and chlorine dioxide--when challenged with a sewage contaminant. The test distribution system consisted of the street main and internal plumbing for two barracks at Fort George G. Meade, MD. To the existing pipe network, 152 m (500 ft) of 13-mm (0.5 in.) copper pipe were added for sampling, and 60 m (200 ft) of 2.54-cm (1.0 in.) plastic pipe were added for circulation. The levels of residual disinfectants tested were 0.2 mg/L and 1.0 mg/L as available chlorine. In the absence of a disinfectant residual, microorganisms in the sewage contaminant were consistently recovered at high levels. The presence of any disinfectant residual reduced the microorganism level and frequency of occurrence at the consumer's tap. Free chlorine was the most effective residual disinfectant and may serve as a marker or flag in the distribution network. Free chlorine and chlorine dioxide were the least stable in the pipe network. The loss of disinfectant in the pipe network followed first-order kinetics. The half-life determined in static tests for free chlorine, chlorine dioxide, and combined chlorine was 140, 93, and 1680 min.
Prevalence of nonpolypoid colorectal neoplasia: An Italian multicenter observational study
Authors: M. Bianco, L. Cipolletta, G. Rotondano, F. Buffoli, G. Gizzi, F. Tessari
Journal: Endoscopy (2010)

Correction to: Prevalence of nonpolypoid colorectal neoplasia: An Italian multicenter observational studyEndoscopy 2010; 42(04): 279-285DOI: 10.1055/s-0029-1244020
Humanitarian medicine
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Predictive Power of Early, Sequential MRD Monitoring in Peripheral Blood and Bone Marrow in Patients with Mantle Cell Lymphoma Following Autologous Stem Cell Transplantation with or without Rituximab Maintenance; Final Results from the LyMa-MRD Project, Conducted on Behalf of the Lysa Group
Authors: Mary B. Callanan, Elizabeth Macintyre, Marie-Helene Delfau-Larue, Catherine Thieblemont, Lucie Oberic, Emmanuel Gyan, Krimo Bouabdallah, Rémy Gressin, Gandhi Damaj, Olivier Casasnovas, Vincent Ribrag, Samuel Griolet, Bénédicte Burlet, Benjamin Tournier, Sylviane Ragot, Caroline Bodet-Milin, Olivier Hermine, Steven Le Gouill
Journal: Blood (2020)
Chirurgie des os et des articulations des membres.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Stylet injury syndrome
Authors: M. Trupp
Journal: JAMA (1977)

Failure to properly use the stylet when withdrawing a spinal puncture needle may cause aspiration of a lumbar nerve root and adjacent arachnoid, thereby fixing the nerve in the epidural space. Root fixation may cause a painful syndrome, requiring laminectomy and replacement of the nerve root within the subarachnoid space. Since laminectomy is rarely performed at the lumbar puncture site, the frequency of the syndrome remains undetermined. (<i>JAMA</i>237:2524, 1977)