tbuckley/cabot-search huggingface dataset:
Accelerated inhibition of platelet activation and aggregation after administration of clopidogrel compared to ticlopidine in patients undergoing coronary intervention Christoph Altmann, Michael Haude, Dirk Welge, Judith Vonnahme, Judith Vonnahme, Heinrich Wieneke, Lothar Volbracht, Raimund Erbel. University Hospital Essen, Essen, Germany
Journal: Journal of the American College of Cardiology (2001)
Effects of 50- or 60-Hertz, 100 mT Magnetic Field Exposure in the DMBA Mammary Cancer Model in Sprague-Dawley Rats: Possible Explanations for Different Results from Two Laboratories
Authors: Larry E. Anderson, James E. Morris, Lyle B. Sasser, Wolfgang Loscher
Journal: Environmental Health Perspectives (2000)

In line with the possible relationship between electric power and breast cancer risk and the underlying melatonin hypothesis, 50-Hz magnetic field (MF) exposure at microtesla flux densities for either 13 or 27 weeks significantly increased the development and growth of mammary tumors in a series of experiments from Löscher's group in Germany.Löscher's group used the 7,12dimethylbenz[a]anthracene (DMBA) model of breast cancer in Sprague-Dawley rats.The finding could not be replicated when a similar experimental protocol was used in a study conducted by Battelle in the United States.In the present paper, investigators from the two groups discuss differences between their studies that might explain the apparent discrepancies between the results.These differences include the use of different substrains of Sprague-Dawley rats (the U.S. rats were more susceptible to DMBA than the European rats), different sources for diet and DMBA, differences in environmental conditions, and differences in MF exposure metrics.Furthermore, the effects of MF exposure reported by Löscher's group, albeit significant, were weak.We also discuss the general problem of replicating such weak effects.
SUCCESSFUL REMOVAL OF AN ENTIRE LUNG FOR CARCINOMA OF THE BRONCHUS
Authors: EVARTS A. GRAHAM
Journal: JAMA (1933)

Carcinoma of the bronchus in recent years has become a problem of major importance. It is now known that primary carcinoma of the lung, which almost always arises in a bronchus, constitutes between 5 and 10 per cent of all carcinomas.<sup>1</sup>In frequency, therefore, it is comparable with carcinoma of the large intestine, and it is much more frequent than the malignant tumors of some other organs that have received much more comment. The problem of primary carcinoma of the lung is of special importance, since up to the present time at least the prognosis has been almost uniformly bad because of the complete futility of any methods of treatment other than surgical excision. There is no record in the literature of the successful treatment by radiotherapy of a single case in which the pathologic evidence has been incontrovertible and in which a five year interval without recurrence has
Vibrio parahaemolyticus in Brazilian coastal waters
Authors: S. M. Franca
Journal: JAMA (1980)

<i>Vibrio parahaemolyticus</i>has been increasingly recognized as an important cause of acute diarrheal illness in Asia, Europe, Africa, Australia, and North America. We investigated whether this pathogen was also present in Brazil and found that 10% of the fish samples studied were contaminated with this halophilic vibrio. Positive cultures were obtained in three of 64 fish (5%) and in seven of 36 shellfish (19%). (<i>JAMA</i>244:587-588, 1980)
Paraproteinemic Maculopathy
Authors: Ahmad M. Mansour, J. Fernando Arevalo, Josep Badal, Ramana S. Moorthy, Gaurav K. Shah, Hernando Zegarra, Jose S. Pulido, Abdulrazzak Charbaji, Luis Amselem, Alejandro Jose Lavaque, Antonio Casella, Baseer Ahmad, Joshua G. Paschall, Antonio Caimi, Giovanni Staurenghi
Journal: Ophthalmology (2014)
Community Report Cards—United States, 1996
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Catgut Preparation.
Authors: Walter L. Hunt
Journal: JAMA (1903)

Bangor, Me., April 4, 1903. <h3>To the Editor:</h3> —As soon as Claudius' method of preparing catgut appeared I carefully prepared some imported gut, Nos. 0, 1 and 2. On trial the gut was brittle and absolutely worthless. The solution is also offensive and black. The same lot of gut was prepared by Hofmeister's method, and is as good as gut can be. The solution is clear and sparkling, and the gut can be boiled without injury. It lasts too long in the tissues, which is a good fault and can be remedied by using the smaller sizes
Letter: Nomenclature for mononucleosis syndromes
Authors: S. C. Cowdrey
Journal: JAMA (1976)

<h3>To the Editor.—</h3> An article with a Latin title "Morituri Te Salutamus" (233:1356, 1975) deserves, I think, correct Latin. However, I am afraid Dr Goldman's Latin is a little rusty in several points: The title, as he had put it, was used by the gladiators to Caesar ("[We], who will die, salute thee, [Caesar]"); since he means to salute the gladiators, it should have been Morituri vos salutamus. In his phrase Ave et atque non vale, either the "et" or the "atque" is repetitious since "et" means the same as "atque." The classical version Ave atque vale meant "Hail and be healthy" (not "hail and farewell"), unless one would use "farewell" not with the meaning of separation, but as "fare [be] well." Ave atque vale, Doctore Leone Aure!
Antagonism of levodopa by papaverine
Authors: R. C. Duvoisin
Journal: JAMA (1975)

PAPAVERINE, the isoquinoline alkaloid, is widely employed in various formulations in the treatment of patients believed to be suffering from cerebral arteriosclerosis. Patients with Parkinson disease may thus be given papaverine preparations when symptoms are suggestive of cerebral vascular insufficiency or appear to represent instances of arteriosclerotic parkinsonism. It seems important, therefore, to call attention to an antagonistic effect of papaverine on the therapeutic response to levodopa recently observed in several patients. The clinical features of this unexpected interaction are illustrated by the first patient in which they were recognized. <h3>Report of a Case</h3> A 71-year-old woman with Parkinson disease of 20 years' duration had responded extremely well to levodopa therapy when it was started in 1968. Subsequently she enjoyed further, sustained improvement despite moderate choreiform dyskinesia on a combined regimen of levodopa and carbidopa from 1971 through May 1974. Then she began to complain of difficulty concentrating, a sense
Acute suppurative thyroiditis caused by Bacteroides melaninogenicus
Authors: R. K. Sharma
Journal: JAMA (1974)

ACUTE suppurative thyroiditis is rare in children. We report here the first case, to our knowledge, caused by<i>Bacteroides melaninogenicus</i>. <h3>Report of a Case</h3> A 2-year-old boy was admitted to Children's Hospital of Newark for sore throat, fever, swelling in the neck, and dysphagia of 24-hours' duration. Four weeks before admission, the child had had fever, accompanied by cough. He had been treated with antibiotics and a cough mixture. On the day before admission, swelling in the neck was noticed, and dysphagia followed. The medical history was normal, and birth, growth, and development had been normal. Temperature was 102.4 F (39.1 C); pulse rate, 160 beats per minute; blood pressure, 94/60 mm Hg; and respiratory rate, 32/min. There was a diffuse swelling in the anterior midcervical region that measured 8 cm at the greatest diameter (from right to left sternocleidomastoid muscles). The mass was tender, moveable with swallowing, and nonfluctuant.
Letter: Jaundice after halothane.
Authors: W Parker, P Shave, B Thom, T Andersson
Journal: BMJ (1974)

Outbreak of Giardiasis SIR,-In April 1971 a group of Swedish students visited Leningrad and subsequently 90% were found to be suffering from Giardia lamblia infestation with associated symptoms in the majority.This outbreak was reported by Andersson et al.,1 who referred to pre- vious outbreaks in similar circumstances.Recently, in November and December 1973, 227 people went on two four-day trips from the Brighton area to Leningrad.A considerable number have suffered from protracted diarrhoea, abdominal pain, nausea, or vomiting since their return.Investigations are proceeding.To date G. lamblia cysts, often in large numbers, have been found in specimens from 27 out of 47 people ex- amined, all of whom have had symptoms sufficient to take them to their family practitioner.We are making this preliminary report in view of the fact that G. lamblia infestation is often regarded as being innocuous in adults and because we are beginning to learn of cases in persons who were not involved in either of these trips, though a visit to Leningrad has remained a common factor.We should like to a-knowledge the interest shown by
Diagnostic medicine gains from DNA probes
Authors: K. Simmons
Journal: JAMA (1985)

Although they've been in use for nearly a decade, deoxyribonucleic acid (DNA) probes are now becoming a research tool with seemingly endless applications for medicine. Among their uses are prenatal diagnosis, detection of pathogens, and diagnosis and typing of viral infections. Referring to their ability to identify one molecule from hundreds of thousands of messenger ribonucleic acid (RNA) strands, one investigator has called the use of DNA probes "the magnet to pull the needle out of the haystack." DNA probes are specific, single-stranded nucleic acid sequences that are used to search for complementary sequences from a pool of single-stranded DNA. Their construction takes advantage of recombinant DNA technology, and as such they are manipulatable laboratory tools. A recent review article on DNA in medicine (<i>Lancet</i>1984;II:908-911) outlines three ways to obtain a probe. The first is used when the amino acid sequence of a gene product (a protein) is known.
Carcinoma of bronchus presenting with Henoch-Schonlein purpura.
Journal: BMJ (1978)

animals revealed renal changes similar to those already described for other acute infective diseases.4Human subjects and higher mammals vary more in their response to bacterial toxins than smaller experimental animals.Hence gross renal changes do not always occur in acute infections or severe endotoxaemia, although albuminuria with a few red cells is surely not uncommon.
Syphilis in the Innocent, Clinically and Historically Considered, with a Plan for the Legal Control of the Disease.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Activin receptors and cellular signaling by the receptor serine kinase family
Authors: L. S. Mathews
Journal: Endocrine Reviews (1994)

AN EMERGING theme in cell signaling research is the multifunctional nature of many growth factors and cytokines. Proteins purified based on distinct activities are often found to have identical structures; furthermore, different members of large growth factor families have similar, although subtly distinct, effects on diverse sets of cells. Such related factors often have related receptors, activation of which turns on common cellular signaling pathways. Understanding both the specificity and the overlap of growth factor signaling will involve elucidation of the unique and shared features of those receptors and their intracellular targets. The activins are growth and differentiation factors that are produced by, and exert effects on, a broad range of cells and tissues (reviewed in Refs. 1–5). With the cloning of several activin receptors, as well as the development of biological models for assessing activin and activin receptor function, substantial progress has been made in understanding the mechanism of action of these potent molecules.
A Resource of Cre Driver Lines for Genetic Targeting of GABAergic Neurons in Cerebral Cortex
Authors: Hiroki Taniguchi, Miao He, Priscilla Wu, Sangyong Kim, Raehum Paik, Ken Sugino, Duda Kvitsiani, Yu Fu, Jiangteng Lu, Ying Lin, Goichi Miyoshi, Yasuyuki Shima, Gord Fishell, Sacha B. Nelson, Z. Josh Huang
Journal: Neuron (2011)
Maternal Smoking during Pregnancy and Postnatal Exposure to Environmental Tobacco Smoke as Predisposition Factors to Acute Respiratory Infections
Authors: Wieslaw Jedrychowski, Elzbieta Flak
Journal: Environmental Health Perspectives (1997)

This study compared susceptibility to respiratory morbidity in a cohort of 9-year-old children exposed congenitally and postnatally to environmental tobacco smoke (ETS) to susceptibility in a cohort of unexposed children. The epidemiologic study included 1129 children: 594 boys and 535 girls attending the second grade of grammar schools in Kraków, Poland. We found strong evidence that children exposed to ETS in their homes were more susceptible to acute respiratory tract illnesses than unexposed children. A dose-response relationship between degree of exposure [for lower ETS exposure, odds ratio (OR) = 1.32; for higher ETS exposure, OR = 1.74] supports a causal explanation for the association observed. The significant trend of increased risk of respiratory infections due to ETS level in nonatopic children whose mothers did not smoke cigarettes during pregnancy suggests a direct effect of ETS exposure on the child's respiratory health. ETS combined with allergy nearly tripled the risk of acute respiratory tract illness (OR = 3.39; 95% CI, 1.93-5.93), and maternal smoking during pregnancy had a modifying effect on the risk of respiratory illnesses due to ETS after accounting for atopy. The stronger effect of ETS in atopic children and in those whose mothers smoked during pregnancy may be result of biologic interaction of endogenous and environmental factors. The results of this study are of relevance to public health policy, as children with higher risk of respiratory infections may be more susceptible to environmental hazards later in adolescence or in adulthood. Respiratory infections also increase demands for medical interventions in terms of outpatient services and hospital administrations. In addition, respiratory illnesses cause missed school days, and caring for a sick child may lead to absenteeism from work.
Incorrect Table Title
Authors: Alexandra Gangi, Galinos Baramparas, Farin Amersi, John Kim
Journal: JAMA Surgery (2015)

Timo W. Hakkarainen, MD, MS; Scott R. Steele, MD; Amir Bastaworous, MD, MBA; E. Patchen Dellinger, MD; Ellen Farrokhi, MD, MPH; Farhood Farjah, MD, MPH; Michael Florence, MD; Scott Helton, MD; Marc Horton, MD; Michael Pietro, MD; Thomas K. Varghese, MD; David R. Flum, MD, MPH
Brain Tumors
Authors: Lisa M. DeAngelis
Journal: New England Journal of Medicine (2001)

The term “brain tumor” refers to a collection of neoplasms, each with its own biology, prognosis, and treatment; these tumors are better identified as “intracranial neoplasms,” since some do not arise from brain tissue (e.g., meningiomas and lymphomas) (Table 1). However, for most intracranial tumors, the clinical presentation, diagnostic approach, and initial treatment are similar. This article will focus on general presentation, diagnosis, and specific treatment.EpidemiologyThe American Cancer Society estimates that 16,800 new intracranial tumors were diagnosed in 1999, more than double the number of diagnosed cases of Hodgkin's disease and over half the number of cases of . . .
Colonic taeniasis
Authors: F. Francois, I. Cho
Journal: Endoscopy (2008)

A 52-year-old Tibetan male was referred for evaluation of rectal bleeding and intermittent mid abdominal pain. He reported frequent loose stools but no associated fever or weight loss. Results from physical exam were within normal limits. Hemoglobin level was 13.1 g/dL (normal range 14 – 18 g/dL), and white-cell count was 5100/mm3 (normal 4800 – 10 800/mm3) with 13 % eosinophils (normal 1 % – 4 %). Colonoscopy revealed small nonbleeding internal hemorrhoids, and a white ribbon-like structure protruding from the ileocecal valve ([Fig. 1]) and extending throughout the entire colon ([Fig. 2]). A segment of the mobile worm was successfully removed using biopsy forceps, and histologic evaluation demonstrated parasite eggs morphologically consistent with Taenia spp. ([Fig. 3], [Video 1]).
Editorial Board
Authors: Paul Atkins, Thomas Casale, Leslie Grammer, Donald Hoffman, Grcen~~ille Nc, Robert Lemanske, Mudison Wi, Diana Marquardt, San Ca, Stephen Peters, Philadelphia Pa, Gary Rachelefsky, Los Angeles, Daniel Stechschulte, Kansas Ks, Stanley Szefler, Denver Co, Jean Bousquet, Martin Chapman, Churlottesville Va, Donald Cockcroft, Stephen Holcate, Southampton Englund, Manuel Lopez, New La, F Estelle, R Simons, Robert Bush, H Madison, London England, Henning Lowenstein, Horsholm Denmark, Jean-Luc Malo, Dennis Ownby, Robert Schleimer
Journal: Journal of Allergy and Clinical Immunology (1993)
Explained unexplained anisocoria
Authors: W. V. Delaney
Journal: JAMA (1980)

UNEQUAL pupils, loss of accommodation, inconsistent field loss, and double vision in near gaze prompted neurological evaluation of a patient. Discontinuation of diphenhydramine hydrochloride therapy for allergies resulted in immediate and permanent reversal of all symptoms and signs. The atropine-like effect of antihistamines needs reemphasis. <h3>Report of a Case</h3> In December 1978, a 14-year-old girl was referred by a neurosurgeon because of persistent complaints about her vision in the left eye. She had had difficulty reading in school throughout the previous year and had not done well academically. In July 1978, she had "passed out" while at school, without any incontinence or convulsion. The episode was brief and associated with a headache. She was subsequently examined by two ophthalmologists, who found an inferior nasal field defect in both of her eyes and a possible superior temporal defect in the left. She described blurred vision in the left eye and was
The Swimmer
Authors: M. Therese Southgate
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Rickettsialpox. Case report and epidemiologic review
Authors: B. Wong
Journal: JAMA (1979)

In recent years, rickettsialpox was infrequently reported: one case per year was recorded by the Public Health Service during the past 15 years. We observed a case of rickettsialpox in New York City and reviewed the clinical, diagnostic, and epidemiologic features. Records of the New York City Health Department showed that serum samples from only six patients were submitted for serological testing for rickettsialpox during the past ten years, suggesting that although the disease is uncommon now, clinicians may be failing to recognize and diagnose rickettsialpox, as it may occur more frequently than is presently recognized. (<i>JAMA</i>242:1998-1999, 1979)
Picture Quiz
Authors: Christos Zipitis
Journal: BMJ (2001)

A 30 year old student presented to an accident and emergency department with peluritic chest pain of six days' duration. He was previously well with no medical or surgical history. He was on no medication. Examination was unremarkable. An electrocardiogram was performed and this was normal. Figures 1 and 2 show the chest x ray film and the computerised tomography scan that were subsequently performed.
THE ROSE SPOTS OF TYPHOID FEVER.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal