tbuckley/cabot-search huggingface dataset:
CATARRHAL INFLAMMATION OF THE MIDDLE-EAR AS A FACTOR IN THE PRODUCTION OF FACIAL PALSY.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Intratracheal Instillation versus Intratracheal Inhalation: Influence of Cytokines on Inflammatory Response
Authors: M. Osier, R. B. Baggs, G. Oberdorster
Journal: Environmental Health Perspectives (1997)

Our laboratory has developed a method of particle exposure whereby anesthetized rats intratracheally inhale, at a regulated breathing rate and pressure, an aerosolized test material.This method is capable of delivering considerable doses in a short time period and, unlike the commonly used method of intratracheal instillation, does so with an even particle distribution throughout the lung.Early studies comparing the response of male Fischer 344 rats exposed to TiO2 particles of two differing primary particle sizes showed that at similar particle doses animals exposed by the two methods showed differences in response, as measured by bronchoalveolar lavage (BAL) parameters.Building on this, we sought to study the roles that macrophage inflammatory protein-2 (MIP-2) and tumor necrosis factor alpha (TNF-a), two cytokines thought to have proinflammatory roles in the lung, may play in the differences observed.Increases in MIP-2 protein levels in the lavaged cells, but not the supernatant, were observed in those groups where increased polymorphonuclear cells (PMN) in the lung lavage were found, but not in those where no increase in PMN levels was observed.BAL TNF-a levels, measured by enzyme-linked immunosorbent assay, showed no apparent correlation with cellular or biochemical BAL parameters for either particle size or dosing method.Increases in immunocytochemical staining for TNF-a, compared to unexposed controls, were observed in several particle-exposed groups.Thus, it appears that increased BAL MIP-2 protein levels, but not TNF-a, correlate well with the inflammatory response, as measured by PMN numbers in lavaged cells, for both exposure systems.
Pneumoconiosis in Animals Exposed to Poly(Vinyl Chloride) Dust
Authors: David H. Groth, Dennis W. Lynch, William J. Moorman, Lloyd E. Stettler, Trent R. Lewis, William D. Wagner, Choudari Kommineni
Journal: Environmental Health Perspectives (1981)

Rats, guinea pigs and monkeys were exposed by inhalation (6 hr/day, 5 days/week) for up to 22 months to a 13 mg/m3 concentration of PVC dust. Autopsies on rats and guinea pigs were performed after 12 months of exposure and on monkeys after 22 months after 22 months of exposure. Lung function tests were performed on monkeys after 9, 14 and 22 months of exposure. Aggregates of alveolar macrophages containing PVC particles were found in the lungs of all animals. These aggregates were more numerous in the monkey lungs. No fibrosis or significant cellular infiltrates were present in or near these cellular aggregates. No significant effects on pulmonary function could be demonstrated in the monkeys exposed to PVC. Under the conditions of this experiment, inhaled PVC produced a benign pneumoconiosis.
<i>Studies in Paranoia.</i>By N. Gieruch, M. D., and M. Friedmann, M. D. Translated and edited by Smith Ely Jelliffe, M. D. Pp. IV + 78, being No. 2 of the Nervous and Mental Disease Monograph Series published by Jour. of Nerv. and Ment. Dis. Pub. Co., 64 W. 56th St., New York
Journal: American Journal of Psychiatry (1909)
Altered hepatocellular Ca2+ regulation during hemorrhagic shock and resuscitation
Authors: S Rose
Journal: Hepatology (1997)

The present study evaluated the effect of the benzothiazepine Ca2+ channel blocker diltiazem (DZ) on altered hepatocellular Ca2+ regulation and oxidant injury during hemorrhagic shock/resuscitation. In anesthetized, male Sprague-Dawley rats, hemorrhagic shock was induced by rapid blood withdrawal and maintaining the mean arterial blood pressure at 40 mm Hg over 60 minutes. Rats were then resuscitated with 60% of shed blood and threefold the shed blood volume of Ringer's lactate. At the end of ischemia, and 60 or 300 minutes after resuscitation, hepatocytes were isolated by liver collagenase perfusion. Hepatocellular Ca2+ exchange (Ca2+ex), rate of cellular Ca2+ influx (Ca2+in), and Ca2+ membrane flux (Ca2+flux) were determined using 45Ca incubation techniques. Hepatocyte oxidant injury was evaluated by fluorometrically measuring thiobarbituric acid reactive substances and oxidized/reduced glutathione. Both hemorrhage and hemorrhage/resuscitation increased hepatocellular Ca2+in, Ca2+ex, and Ca2+flux. In contrast to control and sham-operated rats, in vitro stimulation by the Ca2+ agonist epinephrine (100 nmol/L) of hepatocytes from either hemorrhaged or resuscitated rats did not further increase Ca2+in. Administration of DZ (.8 mg/kg) with resuscitation significantly decreased cellular Ca2+ex and Ca2+flux, but did not restore impaired epinephrine-induced Ca2+in. DZ prevented hepatocyte lipid peroxidation and glutathione oxidation. These findings suggest hepatocellular Ca2+ overload and impaired Ca2+ signaling during hemorrhage/resuscitation. Increased Ca2+ uptake could be because of a receptor-gated Ca2+ influx and/or oxygen-free radical induced membrane Ca2+ leaks.
Radical toxicity of phenols: A reference point for obtaining perspective in the formulation of QSAR
Authors: Rajni Garg, Sanjay Kapur, Corwin Hansch
Journal: Medicinal Research Reviews (2001)

In this report we discuss some of the surprising ways phenols interact in vivo and how some of their toxic activity can be understood in terms of QSAR and in fact can be related via electronic terms to be similar to processes of simple chemical reactions. A simple two-term QSAR is found to be a good predictor of estrogenic toxicity. However, it is also shown that even the simplest of phenols can yield quite unexpected results than can be elucidated via QSAR. We still have a long way to go before we can predict under what conditions a phenol will produce toxic effects such as cancer and how much phytophenols one can consume before reaping a toxic reaction. © 2000 John Wiley & Sons, Inc. Med Res Rev, 21, No. 1, 73–82, 2001
Influence of Reserpine and βTM 10 on Digitalis-Induced Ventricular Arrhythmia
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Harvest
Authors: Gregory Williams
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fallacy of the roentgenologically negative appendix
Authors: W. W. Dietz
Journal: JAMA (1969)

<h3>To the Editor:—</h3> During roentgenologic consultations regarding colon studies, clinicians frequently either inquire specifically if an appendix filled with barium or state in effect that an opacified appendix may be assumed to be normal. Several facets of appendiceal anatomy and pathology invalidate such emphasis upon appendiceal opacification: (1) Appendiceal length varies enormously. Unless the precise length of an appendix is known, it cannot be regarded as opacified in its entirety. (2) Appendicitis is rarely caused by luminal obstruction at the appendiceal base, precluding the entrance of barium. <h3>Report of Cases:—</h3> Case1.—A 67-year-old man with a history of chronic dysuria and nocturia was hospitalized for a prostatectomy after the onset of anuria. The patient complained of nausea, vomiting and abdominal cramps. Physical examination revealed abdominal distention with right lower quadrant tenderness, in addition to prostatic enlargement. A preoperative excretory pyelogram disclosed an incomplete small intestine obstruction, but no urinary tract
Abstract 2514: Endovascular Imaging Causes Significant But Temporary Endothelial Injury
Authors: Willem J Van Der Giessen, Stefan C Krabbendam, Heleen M van Beusekom
Journal: Circulation (2008)

Coronary Imaging e.g. IVUS and OCT to assess vascular size, plaque morphology and composition are useful tools in clinical trials as well as in routine practice. It is unclear whether imaging catheters induce acute endothelial cell damage (ECD) and how this heals over time. Methods. Normal porcine coronary arteries were subjected to intravascular imaging (Raman, IVUS, OCT), guidewire-only placement or no manipulation (control). ECD was assessed acute or at 5 days (chronic) with an Evans Blue dye-exclusion test and planimetry followed by scanning electron microscopy (SEM). Results. Acute injury (% staining of the area exposed to imaging) was considerable, but similar for the 3 imaging catheters. Guidewire-only induced less ECD. One-way ANOVA showed that only OCT- and RAMAN induced more ECD than control. Analysis with SEM showed that staining was associated with either EC denudation or injured but present EC. At 5 days staining was reduced to background levels. Conclusion. Vascular imaging and guide wire manipulation both induce acute ECD, but this injury heals within 5 days following imaging. Planimetry of endothelial injury
Academy of Sciences, Paris: Operation for the Cure of Stuttering
Journal: BMJ (1841)

OF STtITTEIIING. 16.Has been progressing favourably since last report.The limb was placed on its outer side the day before yesterday, and is now perfectly easy.22. The leg has been placed in pasteboard splints, and laid on its fibular side.Tolerably firm union has taken place, and the wound over the fibiula is slowly filling up.He experiences scarcely any pain in the leg.Appetite anid general health good.28. Has been gradually improving since last repott; the leg is becoming very firn; he can raise it from the bed without any assistanice.Jan. 6.Progressing favourably.19.Has been up the last two days.Considerable edema appears about the litnb after he has been up a shiort time.The upper wounid is not entirely healed.There is motion, though slight, of the ancle-joint.A pasteboard splint is applied on the fibular side with a roller.Feb. 2. He is able to walk on it with much more secu- rity, and it does not swell so muclh as before.It is now strapped uniformly with strips of soap-plaster.8. Gaining strength rapidly.15.The patient has left the hospital, the leg being quite firm, and enabling him to walk very well.
Relation Between Anti-Antibodies and Gm-Agglutinins
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hospital staff, victims, families cope with life-altering effects of violence
Authors: M. F. Goldsmith
Journal: JAMA (1992)

THE WRONG PLACE at the wrong time. That's where victims of urban violence say they were when tragedy struck. If their luck changes, they may find themselves afterward in the right place to reclaim a life that has been altered forever by traumatic injury, often from a gun or a knife. This is a story about some of the staff at one of these places and a few of the victims of this country's war against itself. The Rehabilitation Institute of Chicago (RIC) is not only highly esteemed in Illinois, but the<i>U.S. News &amp; World Report </i>"America's Best Hospitals" survey rated it first in the nation (August 5, 1991). It is one of 135 rehabilitation hospitals and 672 rehabilitation units in general hospitals in the United States. Such facilities used to exist primarily to help patients of all ages who were injured in motor vehicle, diving, and other accidents.
DIABETIC NEURITIS.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CAN CARCINOMA BE CURED?
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Education
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Artery-expanding stents widen hopes for patients with atherosclerosis
Authors: M. F. Goldsmith
Journal: JAMA (1988)

"IT MAKES GOOD SENSE to try these stents," Ronald E. Vlietstra, MD, said at the annual American Heart Association meeting in Anaheim, Calif. Vlietstra, a consultant in cardiovascular disease and internal medicine at the Mayo Clinic, Rochester, Minn, was recommending consideration of the newest idea for maintaining patency in atherosclerotic coronary arteries. A stent is a small stainless steel device—about the size of a spring in the old ballpoint pens—designed to be placed permanently in an artery so that it acts as a supporting framework to keep the walls apart, permitting the blood to circulate without obstruction. Three different types of stents were described at the meeting by investigators who think the devices, still in an early stage of development, may one day be used routinely to prevent the restenosis that occurs within six months in up to 30% of some 200 000 patients with cardiovascular disease who undergo percutaneous
DOMESTIC CORRESPONDENCE.
Authors: George H. Rohe
Journal: JAMA (1893)

<h3>To the Editor of the Journal of the American Medical Association:</h3> I am not willing to allow the statements in the editorial article on "Removal of the Ovaries as a Therapeutic Measure in Public Institutions for the Insane" inThe Journalfor February 4, to pass without question. I presume the statements are made on the authority of the distinguished chairman of the Lunacy Committee, of the Pennsylvania Board of Public Charities. Now, while I cheerfully concede Dr. Morton's distinction as a surgeon and teacher and acknowledge my obligations to his many valuable contributions to surgical literature, I cannot allow his sweeping assertions upon this question to pass without a mild protest. Several years ago my attention was attracted by the statement frequently made in medical societies to the effect that many abdominal sections with removal of the uterine appendages had been done in American Insane Hospitals with a view
Hémorragie post polypectomie dans le programme national de dépistage du cancer colique anglais
Journal: Endoscopy (2017)

Le risque principal de la polypectomie est la survenue d’une hémorragie après le geste. Dans la plupart des séries ce risque est chiffré entre 2 à 5 % des gestes. Il y a peu d’études qui se sont intéressées au risque de saignement post-polypectomie dans le cadre des campagnes de dépistage actuellement largement développées en Europe.
WASHINGTON NEWS
Journal: JAMA (1964)

<h3>King-Anderson Developments.—</h3> Final settlement of the so-called Medicare issue was postponed until after the Democratic Convention following the Senate Finance Committee's rejection of three attempts to add a Social Security hospital benefit program for the aging to the House-passed bill raising Social Security cash benefits and taxes. King-Anderson backers said they would force the issue on the floor of the Senate. The Finance Committee also defeated a Housepassed provision placing self-employed physicians under the Social Security System. The Finance Committee voted down several other provisions in the House bill and added two amendments—actions which made it almost certain that the measure would go to a House-Senate Conference Committee to resolve differences in the bills. The Finance Committee, headed by Sen. Harry Byrd (D, Va), defeated 11 to 6 the Administration's King-Anderson measure that was offered by Sen Albert Gore (D, Tenn). By a 12 to 5 vote it rejected a