tbuckley/cabot-search huggingface dataset:
Effect of Delayed Cell Infusion in Patients with Large B-Cell Lymphoma Treated with CAR T-Cell Therapy
Authors: Andrew Jallouk, Lei Feng, Mansoor Noorani, Kaberi Das, Raphael E Steiner, Loretta J. Nastoupil, Misha Hawkins, Ranjit Nair, Jason Westin, Luis Fayad, Dai Chihara, Luis Enrique Malpica Castillo, Swaminathan P. Iyer, Sairah Ahmed, Elizabeth J Shpall, Partow Kebriaei, Sattva S. Neelapu, Paolo Strati
Journal: Blood (2022)
Treatment of Primary Plasma Cell Leukemia with Carfilzomib and Lenalidomide-Based Therapy: Results of the Final Analysis of the Prospective Phase 2 EMN12/HOVON-129 Study for Patients Aged 18-65 Years
Authors: Niels W.C.J. Van De Donk, Monique C. Minnema, Bronno van der Holt, Fredrik Schjesvold, Ka Lung Wu, Andrea Capra, Annemiek Broijl, Wilfried W.H. Roeloffzen, Alain Gadisseur, Giuseppe Pietrantuono, Ludek Pour, Vincent H.J. van der Velden, Thomas Lund, Massimo Offidani, Mariella Grasso, Luisa Giaccone, Michele Cavo, Trine Silkjaer, Jo Caers, Sonja Zweegman, Roman Hájek, Reuben Benjamin, Annette Juul Vangsted, Mario Boccadoro, Francesca Gay, Pieter Sonneveld, Pellegrino Musto
Journal: Blood (2022)
Combination of Ibrutinib and Nivolumab Overcomes Ibrutinib Resistance in a Novel Patient-Derived Mantle Cell Lymphoma 3D Model
Authors: Ferran Araujo-Ayala, Cèlia Dobaño-López, Juan G Valero, Ferran Nadeu, Fabien Gava, Carla Faria, Marine Norlund, Renaud Morin, Pascale Bernes-Lasserre, Neus Serrat, Heribert Playa-Albinyana, Rubén Giménez, Elías Campo, Jean Michel Lagarde, Armando López-Guillermo, Eva Giné, Dolors Colomer, Christine Bezombes, Patricia Pérez-Galán
Journal: Blood (2022)
Chronic Myeloid Leukemia in Adolescents and Youngadults: Clinicopathological Variables and Outcomes
Authors: Mohammad Abdul-Jaber Abdulla, Mahmood B Aldapt, Prem Chandra, Susanna Jane Akiki, Liam Fernyhough, Sundus Sardar, Ammar Chapra, Abdulqadir Jeprel Nashwan, Mohamed A Yassin
Journal: Blood (2022)
Effect of MRD Level after Induction Therapy and Post-Remission Treatment on Prognosis of ALL Patients
Authors: Xue Sun, Xiaosheng Fang, Xiaoqian Liu, Ying Li, Xue Shi, Yahan Li, Ran Tan, Yujie Jiang, Xiaohui Sui, Xueling Ge, Hongzhi Xu, Xin Wang
Journal: Blood (2022)
Mutational Analysis of <i>DNMT3A</i> Improves the Prognostic Stratification Using <i>NPM1</i>/<i>FLT3</i>-ITD Genotypes in Patients with Acute Myeloid Leukemia
Authors: Atsushi Marumo, Satoshi Wakita, Kaoru Morita, Shinichi Kako, Takashi Toya, Yuho Najima, Noriko Doki, Junya Kanda, Junya Kuroda, Shin-Ichiro Mori, Atsushi Satake, Kensuke Usuki, Toshimitsu Ueki, Nobuhiko Uoshima, Yutaka Kobayashi, Eri Kawata, Kazutaka Nakayama, Yuhei Nagao, Katsuhiro Shono, Motoharu Shibusawa, Jiro Tadokoro, Masao Hagihara, Hitoji Uchiyama, Naoyuki Uchida, Yasushi Kubota, Shinya Kimura, Hisao Nagoshi, Tatsuo Ichinohe, Saiko Kurosawa, Sayuri Motomura, Hashimoto Akiko, Hideharu Muto, Eriko Sato, Masao Ogata, Kenjiro Mitsuhashi, Jun Ando, Haruko Tashiro, Masahiro Sakaguchi, Shunsuke Yui, Kunihito Arai, Tomoaki Kitano, Miho Miyata, Takahiro Fukuda, Yoshinobu Kanda, Hiroki Yamaguchi
Journal: Blood (2022)
Concerns about Prognostic Meaning of Quantitative PET Analysis in Classical Hodgkin Lymphoma
Authors: Fernanda Maria Maria Santos, Jose Flavio Gomes Marin, Marcos Santos Lima, Wellington F Silva, Rodrigo D Velasques, Ana Carolina Arrais Maia, Marcelo Junqueira Atanazio, Lucas Bassolli de Oliveira Alves, Frederico Rafael Moreira, Carlos Alberto Buchpiguel, Valeria Buccheri, Vanderson Rocha
Journal: Blood (2022)
Incremental Clinically Relevant Information in 70 CLL Cases with Optical Genome Mapping: Going Beyond Karyotype and FISH
Authors: Nikhil Sahajpal, Anand P. Jillella, Ashis Mondal, Harmanpreet Singh, Ashutosh Vashisht, Huidong Shi, Vamsi K. Kota, Ravindra Kolhe
Journal: Blood (2022)
Geographical CAR-T Unmet Needs for Patients with Large B-Cell Lymphoma in the Province of Quebec
Authors: Maria Murphy, Mathilde Fromentin, Julie Campeau, Michael Sebag, Félix Couture, Jean-François Larouche, Christopher Lemieux, Silvy Lachance, Sandra Cohen, Luigina Mollica, Olivier Veilleux, Isabelle Fleury
Journal: Blood (2022)
Epidemiology of Non-Hodgkin Lymphoma: Global Patterns of Incidence, Mortality, and Trends
Authors: Ephrem Sedeta, Nosakhare Ilerhunmwuwa, Mustafa Wasifuddin, Ifeanyi Uche, Narek Hakobyan, Jamal Perry, Henry Aiwuyo, Hesham Abowali, Boris Avezbakiyev
Journal: Blood (2022)
Presence of Measurable Residual Disease in NPM1 Positive AML in Remission Pre-Transplant Does Not Impact on Survival after Allogeneic Hematopoietic Stem Cell Transplantation
Authors: Alessia Fraccaroli, Elena Stauffer, Katrin Koch, Klaus Hirschbühl, Stephan Breitkopf, Frank Ziemann, Heidrun Drolle, Maja Rothenberg-Thurley, Annika Maria Dufour, Klaus H. Metzeler, Michael von Bergwelt, Karsten Spiekermann, Andreas Hausmann, Christoph Schmid, Mareike Verbeek, Tobias Herold, Johanna Tischer
Journal: Blood (2022)
A Phase 1/2, Dose and Schedule Evaluation Study to Investigate the Safety and Clinical Activity of Belantamab Mafodotin Administered in Combination with Lenalidomide and Dexamethasone in Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma
Authors: Evangelos Terpos, Maria Gavriatopoulou, Ioannis Ntanasis-Stathopoulos, Panagiotis Malandrakis, Despina Fotiou, Nikolaos Kanellias, Magdalini Migkou, Foteini Theodorakakou, Vasiliki Spiliopoulou, Rodanthi Syrigou, Evangelos Eleutherakis Papaiakovou, Stavros Gkolfinopoulos, Kyriaki Manousou, Efstathios Kastritis, Meletios A. Dimopoulos
Journal: Blood (2022)
Absolute Lymphocyte Count and Outcomes of Multiple Myeloma Patients Treated with Idecabtagene Vicleucel: The U.S. Myeloma CAR T Consortium Real World Experience
Authors: Jack Khouri, Hong Li, Doris K. Hansen, Surbhi Sidana, Leyla O. Shune, Shaun DeJarnette, Faiz Anwer, Douglas W Sborov, Charlotte B Wagner, M. Hakan Kocoglu, Shebli Atrash, Peter M. Voorhees, Jason Valent, Lauren C. Peres, Vanna Hovanky, Gary Simmons, Danai Dima, Nilesh Kalariya, Aimaz Afrough, Gurbakhash Kaur, Aishwarya Sannareddy, Christopher J. Ferreri, James Davis, Joseph P. McGuirk, Frederick L. Locke, Rachid C. Baz, Betty K. Hamilton, Melissa Alsina, Craig S. Sauter, Hamza Hashmi, Krina Patel
Journal: Blood (2022)
Initial Results of a Phase 1 Study of Daratumumab, Ixazomib, and Dexamethasone in Newly Diagnosed and Previously Treated AL Amyloidosis
Authors: Hans C. Lee, Gregory P. Kaufman, Lei Feng, Astrid Murga, Ralph J. Johnson, Donna M. Weber, Sheeba K Thomas, Qaiser Bashir, Muzaffar H Qazilbash, Swaminathan P. Iyer, Krina Patel, Melody R. Becnel, Elisabet E. Manasanch, Robert Z. Orlowski
Journal: Blood (2022)
TP53 CRISPR/Cas9 Reveals Strict BAX Dependence in the Response to BH3 Mimetic Targeting MCL1
Authors: Romane Durand, Domitille Costes-Tertrais, Geraldine Descamps, Christelle Dousset, Sophie Maïga, Jean-Baptiste Alberge, Elise Douillard, Jennifer Derrien, Celine Bellanger, David Chiron, Stephane Minvielle, Cyrille Touzeau, Philippe Moreau, Martine Amiot, Patricia Gomez-Bougie, Agnes Moreau-Aubry, Catherine Pellat-Deceunynck
Journal: Blood (2022)
Rapamycin Inhibits Cytotoxic T Lymphocytes-Mediated Platelet Destruction in Immune Thrombocytopenia
Authors: Xiaofei Ni, Yajing Zhao, Tianshu Yu, Haoyi Wang, Lingjun Wang, Pengcheng Xu, Hai Zhou, Yanfeng Liu, Xinguang Liu, Yu Hou, Jihua Qiu, Ming Hou
Journal: Blood (2022)
Efficacy and Safety of Tyrosine Kinase Inhibitors in the Treatment of Relapsed/Refractory Immune Thrombocytopenia
Authors: Muhammad Ashar Ali, Memoona Saeed, A. Supraja, Maha Zafar, Ashish Nepal, Muhammad Suleman, Rooma Habib, Sana Rashid, Sumaiya Asfund, Muhammad Abdul Basit, Hafsa Zahoor, Sviatoslav Kosach, Aqsa Anwar, Wajeeha Aiman
Journal: Blood (2022)
Treatment and Disease Characteristics of Chronic Myeloid Leukemia in Blast Crisis: The European Leukemianet Blast Crisis Registry
Authors: Annamaria Brioli, Elza Lomaia, Christian Fabisch, Tomasz Sacha, Hana Klamová, Elena Morozova, Aleksandra Golos, Philipp Ernst, Ulla Olsson-Strömberg, Jiri Mayer, Franck E. Nicolini, Han Bao, Fausto Castagnetti, Elzbieta Patkowska, Klaus Hirschbühl, Edyta Paczkowska, Anne Parry, Astghik Voskanyan, Susanne Saussele, Georg-Nikolaus Franke, Alexander Kiani, Edgar Faber, Krzysztof Lewandowski, Stefan W. Krause, Elke Dammann, Peter Anhut, Justyna Gil, Thomas Südhoff, Sonja Heibl, Markus Pfirrmann, Andreas Hochhaus, Michael Lauseker
Journal: Blood (2022)
Representative oral microbiome data for the US population: the National Health and Nutrition Examination Survey
Authors: Emily Vogtmann, Anil K Chaturvedi, Martin J Blaser, Nicholas A Bokulich, J Gregory Caporaso, Maura L Gillison, Xing Hua, Autumn G Hullings, Rob Knight, Vaishnavi Purandare, Jianxin Shi, Yunhu Wan, Neal D Freedman, Christian C Abnet
Journal: The Lancet Microbe (2022)
Liposome-based nanoparticles impact on regulatory and effector phenotypes of macrophages and T cells in multiple Sclerosis patients
Authors: Maria Tredicine, Francesco Ria, Noemi Poerio, Matteo Lucchini, Assunta Bianco, Federica De Santis, Mariagrazia Valentini, Valeria De Arcangelis, Mario Rende, Anna Maria Stabile, Alessandra Pistilli, Chiara Camponeschi, Viviana Nociti, Massimiliano Mirabella, Maurizio Fraziano, Gabriele Di Sante
Journal: Biomaterials (2022)
Hematopoietic Cell Transplantation in First Remission in AML in Mexico: Very Low Rates Derived from Early Relapses and Lack of Access
Authors: Ruben Solis-Armenta, Andrea Priscila Hernandez Perez, Nidia Paulina Zapata, Nancy Delgado, Efreen H Montano Figueroa, Faustino . Leyto, Juan Carlos Solís-Poblano, Andres Gomez-De Leon, Lauro Fabian Amador, Carolina García-Castillo, Ramon Martinez Hernandez, Hugo Alexis Saldaña Velázquez, Espinoza Ramiro, Victor Itaí Urbalejo Ceniceros, Valentín Lozano-Zavaleta, Eduardo Terreros, Mark A. Jiménez, Andrea Milan Salvatierra, Perla Rocio Colunga Pedraza, David Gomez-Almaguer, Luisa M Alcivar, Elia Apodaca Chavez, Mario Meza, Fabiola Yocupicio, Susana Sánchez-Díaz, Rafael Lope-Herrera, Roberta Demichelis
Journal: Blood (2022)
Mosunetuzumab Monotherapy Continues to Demonstrate Promising Efficacy and Durable Complete Responses in Elderly/Unfit Patients with Previously Untreated Diffuse Large B-Cell Lymphoma
Authors: Adam J. Olszewski, Abraham Avigdor, Sunil Babu, Itai Levi, Herbert Eradat, Uri Abadi, Houston Holmes, Matthew McKinney, Dariusz Woszczyk, Krzysztof Giannopoulos, Wojciech Jurczak, Diana Dunshee, Annie Yang, Mingzhu Zhou, Naseer Qayum, Gila Sellam, Netanel A. Horowitz
Journal: Blood (2022)
The CAR-Hematotox Score Identifies Patients at High Risk for Hematological Toxicity, Infections and Poor Clinical Outcomes Following Brexucabtagene Autoleucel in Relapsed/Refractory Mantle Cell Lymphoma
Authors: Kai Rejeski, Yucai Wang, Omar Albanyan, Javier L Munoz, Pierre Sesques, Gloria Iacoboni, Lucía López Corral, Razan Mohty, Martin Dreyling, Frederick L. Locke, Pere Barba, Emmanuel Bachy, Yi Lin, Marion Subklewe, Michael D. Jain
Journal: Blood (2022)
Prognostic Value of Translocation 11;14 in Patients with Relapsed/Refractory Myeloma Receiving Anti-CD38 Therapy
Authors: Ghulam Rehman Mohyuddin, Rajshekhar Chakraborty, Gregory Calip, Mustafa S Ascha, Xiaoliang Wang, Samuel Rubinstein, Sascha A. Tuchman, Luciano J. Costa, Benjamin Haaland, Smith Giri, Hira S Mian, Rafael Fonseca, Douglas W. Sborov
Journal: Blood (2022)
Trial in Progress: An Open-Label Phase II Study of Relatlimab with Nivolumab in Combination with 5-Azacytidine for the Treatment of Patients with Relapsed/Refractory and Elderly Patients with Newly Diagnosed Acute Myeloid Leukemia (AARON)
Authors: Veit L Buecklein, Maximilian Warm, Karsten Spiekermann, Christian Schmidt, Michael Unterhalt, Naval Daver, Marion Subklewe
Journal: Blood (2022)
Early Relapse within 24 Months after Frontline Systemic Therapy (POD24) Is Associated with Worse Survival in Patients with Marginal Zone Lymphoma: A US Multisite Study
Authors: Narendranath Epperla, Rui Li, Pallawi Torka, Lauren Shea, Reem Karmali, Andrea Anampa-Guzman, Timothy Seijung Oh, Kathryn Lindsey, Irl Brian Greenwell, Sayan Mullick Chowdhury, Kaitlin Annunzio, Beth Christian, Geoffrey Shouse, Alex F. Herrera, Nancy L. Bartlett, Natalie S. Grover, Adam J. Olszewski
Journal: Blood (2022)
Population Pharmacokinetics of Mycophenolic Acid in Haploidentical Transplant Recipients Receiving Post-Transplant Cyclophosphamide Based GvHD Prophylaxis
Authors: Aswin Anand PAI, Uday Kulkarni, Binu Susan Mathew, Nayanthara KB, John C Panetta, Sujith Karumathil, Aby Abraham, Vikram Mathews, Biju George, Poonkuzhali Balasubramanian
Journal: Blood (2022)
Expanding access to biotherapeutics in low-income and middle-income countries through public health non-exclusive voluntary intellectual property licensing: considerations, requirements, and opportunities
Authors: Sébastien Morin, Giulia Segafredo, Manuele Piccolis, Aditi Das, Meghmala Das, Nicola Loffredi, Amina Larbi, Kim Mwamelo, Elena Villanueva, Sandra Nobre, Esteban Burrone
Journal: The Lancet Global Health (2022)
Quadruplet Induction, Autologous Transplantation and Minimal Residual Disease Adapted Consolidation and Treatment Cessation in Older Adults ≥70y with Newly Diagnosed Multiple Myeloma: A Subgroup Analysis of the Master Trial
Authors: Smith Giri, Saurabh Chhabra, Eva Medvedova, Bhagirathbhai Dholaria, Timothy Martin Schmidt, Kelly N. Godby, Rebecca Silbermann, Binod Dhakal, Susan Bal, Anita D'Souza, Aric C. Hall, Pamela Hardwick, Jim Omel, Robert Frank Cornell, Natalie Callander, Parameswaran Hari, Luciano J. Costa
Journal: Blood (2022)
Cerebral Palsy and Maternal Injury During Pregnancy
Authors: Zeyan Liew, Haoran Zhuo
Journal: JAMA Pediatrics (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Pediatrics HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Pediatrics journal
Sex disparity in childhood cancer in India: a multi-centre, individual patient data analysis
Authors: Kanu Priya Bhatia, Shuvadeep Ganguly, Archana Sasi, Vivek Kumar, Suryanarayana Deo, Sandeep Agarwala, Venkatraman Radhakrishnan, Rajaraman Swaminathan, Gauri Kapoor, Nalliah Manoharan, Sumit Malhotra, Deepam Pushpam, Sameer Bakhshi
Journal: The Lancet Oncology (2022)
Analysis of Failure Rates for COVID-19 Entrance Screening at a US Academic Medical Center
Authors: Scott C. Roberts, Ridwan N. Faruq, Anne K. Wilkinson, Dinesh S. Pashankar, Mark Russi, Babar Khokhar, Richard A. Martinello
Journal: JAMA Internal Medicine (2022)

This quality improvement study analyzes the rate of failures in entrance screening for COVID-19 among individuals entering a large academic medical center.
Autoimmune Encephalitis—Misdiagnosis, Misconceptions, and How to Avoid Them
Authors: Josep Dalmau, Francesc Graus
Journal: JAMA Neurology (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Neurology HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Neurology journal
Frequency of Approval and Marketing of Biosimilars With a Skinny Label and Associated Medicare Savings
Authors: Alexander C. Egilman, Victor L. Van de Wiele, Benjamin N. Rome, Jonathan J. Darrow, S. Sean Tu, Aaron S. Kesselheim, Ameet Sarpatwari
Journal: JAMA Internal Medicine (2022)

This cohort study assesses the frequency of approval and marketing of skinny-label biosimilars and their savings to Medicare.
Loss of neuromuscular junction integrity and muscle atrophy in skeletal muscle disuse
Authors: Giuseppe Sirago, Maria A. Pellegrino, Roberto Bottinelli, Martino V. Franchi, Marco V. Narici
Journal: Ageing Research Reviews (2022)

Physical inactivity (PI) is a major risk factor of chronic diseases. A major aspect of PI is loss of muscle mass and strength. The latter phenomenon significantly impacts daily life and represent a major issue for global health. Understandably, skeletal muscle itself has been the major focus of studies aimed at understanding the mechanisms underlying loss of mass and strength. Relatively lesser attention has been given to the contribution of alterations in somatomotor control, despite the fact that these changes can start very early and can occur at multiple levels, from the cortex down to the neuromuscular junction (NMJ). It is well known that exposure to chronic inactivity or immobilization causes a disproportionate loss of force compared to muscle mass, i.e. a loss of specific or intrinsic whole muscle force. The latter phenomenon may be partially explained by the loss of specific force of individual muscle fibres, but several other players are very likely to contribute to such detrimental phenomenon. Irrespective of the length of the disuse period, the loss of force is, in fact, more than two-fold greater than that of muscle size. It is very likely that somatomotor alterations may contribute to this loss in intrinsic muscle force. Here we review evidence that alterations of one component of somatomotor control, namely the neuromuscular junction, occur in disuse. We also discuss some of the novel players in NMJ stability (e.g., homer, bassoon, pannexin) and the importance of new established and emerging molecular markers of neurodegenerative processes in humans such as agrin, neural-cell adhesion molecule and light-chain neurofilaments.
Ominous T-Wave Changes in an Older Adult With Chest Pain
Authors: Zhiqiang Zhao, Ziheng Jia, Tong Liu
Journal: JAMA Internal Medicine (2022)

This case report describes a patient in their 60s who presented to the emergency department with acute, severe precordial chest pain radiating to their left arm at night, accompanied by dyspnea, dizziness, and sweating.
Mortality Among Pediatric Patients With Acute Lymphoblastic Leukemia in Sweden From 1988 to 2017
Authors: Thomas Björk-Eriksson, Martina Boström, Ing-Liss Bryngelsson, Päivi M. Lähteenmäki, Marianne Jarfelt, Marie Kalm, Daniel S. Olsson
Journal: JAMA Network Open (2022)

Acute lymphoblastic leukemia (ALL) constitutes 20% to 30% of all pediatric cancers. The 5-year overall survival among pediatric patients with ALL in high-income countries such as Sweden is currently more than 90%, but long-term unselected nationwide mortality data and mortality data in relation to the general population are lacking.To compare mortality between pediatric patients with ALL and the general population during a 30-year period in Sweden and to assess the incidence of ALL in Sweden.This cohort study included pediatric patients (aged <18 years) with a morphologically verified ALL diagnosis in the Swedish Cancer Register and/or at least 2 ALL diagnoses in the Swedish National Patient Register between January 1, 1988, and December 31, 2017. Data were cross-linked to the Swedish Cause of Death Register. Data were analyzed from May 2019 to January 2022.The main outcomes were mortality among patients with ALL compared with that in the general population and mortality in different subgroups within the cohort. Standardized mortality ratios (SMRs) were calculated using the general Swedish population as a reference. Within-cohort survival analyses were performed.A total of 2397 patients (1354 [56%] male; mean [SD] age at diagnosis, 6.1 [4.7] years) were included in the study. The mean (SD) incidence of pediatric ALL during the study period was 4.11 (0.60) cases per 100 000 persons per year (females, 3.68 [0.65] cases per 100 000 persons per year; males, 4.52 [0.81] cases per 100 000 persons per year; P < .001). The observed number of deaths among pediatric patients with ALL was 409 vs the 9.5 deaths expected in the general population, resulting in an overall SMR of 43.1 (95% CI, 39.0-47.5); females had a higher SMR than males (57.8 [95% CI, 49.5-67.2] vs 34.5 [95% CI, 32.0-41.4]; P < .001). Analysis within the cohort showed a continued decrease in survival throughout the 30-year follow-up. The association between calendar year of ALL diagnosis, corresponding with different ALL treatment protocols, and mortality showed the lowest survival for the 1988-1991 group and the highest for the 2008-2017 group (χ2 = 20.3; P < .001).In this cohort study, a consistently high SMR was seen among pediatric patients with ALL. Within the ALL cohort, survival evolved to a similar extent as in the young general population of Sweden. Furthermore, survival among patients with ALL decreased throughout the whole follow-up period without any trend difference after the 5-year follow-up time point. The changes in ALL treatment protocols were associated with overall improved absolute survival over time.