tbuckley/cabot-search huggingface dataset:
Patterns of Use and Impact of Post-Referral and Bridging Therapy on Outcomes in Patients Undergoing CAR T-Cell Therapy for B-Cell Lymphoma: A Single-Center Analysis
Authors: Shakthi Bhaskar, Katherine Baker, Danielle Fishman, Spencer Lessans, Bhagirathbhai Dholaria, Reena Jayani, Adetola A. Kassim, Tae Kon Kim, David Morgan, Olalekan O. Oluwole, Bipin N. Savani, Salyka Sengsayadeth, Vivek Patel
Journal: Blood (2023)
Live Lymphoma and CLL Cells inside the Bone Marrow Fibroblasts: Implication in Residual Disease Persistence
Authors: Y. Lynn Wang, Carrie Frazen, Andrey Efimov, Priyal Patel, Pin Lu, Shuo Ma, Katherine Amira Carrol, Edna Cukierman, Marcus R. Messmer, Janusz Franco-Barraza, Juehua Gao, Aldana Vistarop
Journal: Blood (2023)
Marstacimab, an Anti-Tissue Factor Pathway Inhibitor, in Participants with Hemophilia Α or B, with and without Inhibitors: An Integrated Analysis of Safety
Authors: Suchitra Acharya, Davide Matino, Johnny Mahlangu, Carrie Turich Taylor, Eunhee Hwang, Tina Hinnershitz, Eugeny Mefyod, Andrew Palladino, Francesca Biondo, Travis Gould, John Teeter
Journal: Blood (2023)
Methods of Estimating Renal Function for Use in Clinical Trial Eligibility Criteria Widely Vary in Phase II and III Clinical Trials in Acute Myeloid Leukemia
Authors: Priyanka Pullarkat, Yael Flamand, Harish Seethapathy, Meghan Sise, Andrew M. Brunner, Amir T. Fathi, Rupa Narayan
Journal: Blood (2023)
Preliminary Results of the Oral CD73 Inhibitor, Oric-533, in Relapsed/Refractory Multiple Myeloma (RRMM)
Authors: Cesar Rodriguez, Scott R. Solomon, Barry Paul, Omar Nadeem, Meenal Patel, Jian Wang, Rongda Xu, Melissa Junttila, Anneleen Daemen, Subhash Katewa, Pratik S Multani, Wilson I. Gonsalves
Journal: Blood (2023)
A Phase II Study of Clinical Efficacy of Venetoclax in Combination with Azacitidine in Patients with Therapy Related Myelodysplastic Syndrome (t-MDS)
Authors: Uma M. Borate, Kaitlyn M. Dvorak-Kornaus, Qiuhong Zhao, Kristin L Koenig, Ann-Kathrin Eisfeld, Yazan F. Madanat
Journal: Blood (2023)
Post Allogeneic Stem Cell Transplant Outcomes Following Response to Hypomethylating Agent Therapy in Myelodysplastic Syndromes Are Predicted By Persistent International Prognostic Scoring System-Molecular Risk
Authors: Stacey M Frumm, Haesook T. Kim, Amar H Kelkar, Vincent T. Ho, Mahasweta Gooptu, Christopher James Gibson, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai Shimony, Jan Philipp Bewersdorf, Tariq Kewan, Abdulrahman Alhajahjeh, Marlise R. Luskin, Jacqueline S. Garcia, Evan C. Chen, Andrew A. Lane, Martha Wadleigh, Eric S. Winer, Richard M Stone, Daniel J. DeAngelo, Amer M. Zeidan, Coleman Lindsley, Corey Cutler, Maximilian Stahl
Journal: Blood (2023)
Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) Treated with Pegcetacoplan: Real Life Experience
Authors: Carlos Vallejo, Santiago Bonanad Boix, Fernando Carnicero, Anna Gaya, Ana Pilar Gonzalez, Fernando Ataulfo Gonzalez Fernandez, Esperanza Lavilla, Eduardo José Salido, Piva Sanchez Anton, Míriam Vara
Journal: Blood (2023)
Population Pharmacokinetics (PopPK) and Exposure-Response (E-R) Analyses for Belantamab Mafodotin Monotherapy in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) Enrolled in DREAMM-2 and DREAMM-3
Authors: Geraldine Ferron-Brady, Adekemi Taylor, Josh Kaullen, Kishore Polireddy, Astrid McKeown, Neal Sule, Herbert Struemper
Journal: Blood (2023)
MRD Monitoring By Euroclonality IGH Based NGS Approach Predicts Outcome in Follicular Lymphoma Patients Lacking a Conventional BCL2::IGH Marker: A Substudy from the Fondazione Italiana Linfomi (FIL) FOLL12 Trial
Authors: Elisa Genuardi, Beatrice Alessandria, Irene Della Starza, Francesca Guerrini, Riccardo Bomben, Daniela Drandi, Martina Ferrante, Clara Bono, Roberta Soscia, Tamara Bittolo, Simone Ragaini, Salvatrice Mancuso, Emanuele Cencini, Nicola Di Renzo, Clara Mannarella, Marco Murineddu, Vittorio Stefoni, Riccardo Centurioni, Luca Baldini, Aurora Maria Civita, Valter Gattei, Sara Galimberti, Ilaria Del Giudice, Benedetto Bruno, Massimo Federico, Marco Ladetto, Christiane Pott, Stefano Luminari, Simone Ferrero
Journal: Blood (2023)
Upfront Autologous Stem Cell Transplantation in Myeloma Patients &amp;gt;65 Years: A Population-Based Study from the Nordic Myeloma Study Group
Authors: Kari Lenita Falck Moore, Anna Genell, Ain Kaare, Dorota Knut-Bojanowska, Diana Loigom, Anna Lysen, Jakob Nordberg Nørgaard, Katrin Palk, Maris Pärnat, Valdas Peceliunas, Sæmundur Rögnvaldsson, Fredrik Schjesvold, Alexander Sigurdsson, Agoston Gyula Szabo, Jonathan Thorsen, Sigrun Thorsteinsdottir, Vilmantė Vaitekėnaitė, Annette J. Vangsted, Cecilie Hveding Blimark
Journal: Blood (2023)
The Novel CDK9/CDK4/6/PI3K Triple Inhibitor LCI139 for the Treatment of <i>MYC</i>-Driven Mantle Cell Lymphoma
Authors: Dhananjaya Pal, Page Mangum Arditti, Krishnaiah Maddeboina, Cody C. McHale, Hsih-Te Yang, Bharath Yada, Hailey Lynn Dryden, David M Foureau, Donald L. Durden
Journal: Blood (2023)
Vdpace As Salvage Therapy in Triple Class Relapse/Refractory Multiple Myeloma
Authors: Priyanka Venkatesh, Sara Shatnawi, Yara Shatnawi, Hira Shaikh, Christopher Strouse, Shebli Atrash, Muhammad Umair Mushtaq, Nausheen Ahmed, Zahra Mahmoudjafari, Al-Ola Abdallah, Leyla Shune
Journal: Blood (2023)
Impact of Outpatient Administration of Cytarabine Consolidation Chemotherapy on Hospital Length of Stay in Adults with Acute Myeloid Leukemia
Authors: Nicholas Viiala, Omali Pitiyarachchi, Heather Range, Joseph Descallar, Rebecca Han Nguyen, John Dang Trinh Nguyen, Ashley Kate McEwan, Bartlomiej Getta, Lindsay Cameron Dunlop
Journal: Blood (2023)
Venetoclax Exposure Reduction in Venetoclax-Hypomethylating Agents Combination Is Feasible and Has the Same Efficacy in Patients with Acute Myeloblastic Leukemia. Experience of a Single Center
Authors: Iago Arribas, Helena Pomares, Teresa Quiñones, Jasson Villarreal Hernandez, Julia Ribes-Amoros, Clara Maluquer Artigal, Shiomara Quiñones, Maria Isabel Sotelo, María Alicia Senin, Mercedes Galiano, Enric Gamundí, Lurdes Zamora, Neus Ruiz Xiville, Anna Maria Sureda Balari, Montserrat Arnan Sangerman
Journal: Blood (2023)
Baseline 18f-Fluorodeoxyglucose PET/CT Radiomics Predicts Outcome in Newly Diagnosed Intravascular Large B-Cell Lymphoma
Authors: Shinpei Harada, Hideki Goto, Hajime Senjo, Keito Suto, Shiro Watanabe, Koh Izumiyama, Masayo Yamamoto, Kazuya Sato, Yasutaka Kakinoki, Tomoyuki Saga, Akio Shigematsu, Hiroto Horiguchi, Mutsumi Takahata, Reiki Ogasawara, Satoshi Yamamoto, Keisuke Yamaguchi, Kentaro Wakasa, Tetsuyuki Igarashi, Yoshihito Haseyama, Shinichi Ito, Katsuya Fujimoto, Junichi Hashiguchi, Masao Nakagawa, Daigo Hashimoto, Takanori Teshima
Journal: Blood (2023)
Dysregulated Alternative Splicing in Inv(16) Acute Myeloid Leukemia Via U2AF1 Deacetylation during DNA Damage Response
Authors: Lianjun Zhang, Yu-Hsuan Fu, Wei-Kai Hua, Le Xuan Truong Nguyen, Yinghui Zhu, Ying-Chieh Chen, Xin He, Man Li, Haojie Dong, Bin Zhang, Ling Li, Jeremy Stark, Guido Marcucci, Ya-Huei Kuo
Journal: Blood (2023)
Phase 2 Study of Anakinra to Prevent CRS and Neurotoxicity after Treatment with Lisocabtagene Maraleucel: Planned Interim Analysis
Authors: Emily C Liang, Aya Albittar, Andrew J Portuguese, Jennifer J. Huang, Qian Wu, Joseph De Los Reyes, Nikki Pin, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Sylvain Simon, Tony Chour, Evan W. Newell, Mazyar Shadman, Alexandre V Hirayama, Brian G Till, Erik L Kimble, Lorenzo Iovino, Aude G Chapuis, Folashade Otegbeye, Ryan D Cassaday, Filippo Milano, David G Maloney, Jordan Gauthier
Journal: Blood (2023)
Phase 1/2 First-in-Human Study of the Menin-MLL Inhibitor DSP-5336 in Patients with Relapsed or Refractory Acute Leukemia
Authors: Naval Daver, Joshua F. Zeidner, Junichiro Yuda, Justin M. Watts, Mark J. Levis, Kentaro Fukushima, Takayuki Ikezoe, Yoshiaki Ogawa, Joseph Brandwein, Eunice S. Wang, Yasushi Miyazaki, Timothy Pardee, Naoko Hosono, Takahiro Shima, Hisayuki Yokoyama, Noboru Asada, Joseph Jurcic, Hongliang Cai, Akinobu Watanabe, Matthew Hitron, Emily Brooks, Bo Xu, Jatin Shah, Hagop M. Kantarjian, Harry P. Erba
Journal: Blood (2023)
Design of an Observational Study (PROVE) to Assess the Long-Term Effects of Prophylaxis with Simoctocog Alfa or Emicizumab on Joint and Bone Health in Hemophilia a Patients
Authors: Robert Klamroth, Robert F Sidonio, Yesim Dargaud, Víctor Jiménez-Yuste, Rolf Ljung, Guy Young, Pratima Chowdary
Journal: Blood (2023)
Next Generation Sequencing and Cytogenetics in Acute Myeloid Leukemia - Therapeutic and Prognostic Impact: A Retrospective Cohort from a Private Centre of Reference in Latin America
Authors: Felipe Galvão Batista Chaves, Juliana Dall'Agnol da Rocha, Leonardo Javier Arcuri, Paulo Vidal Campregher, Fabio P. S. Santos, Carolina Perrone Marques, Jade Zezzi Martins do Nascimento, Tarcila Santos Datoguia, Amanda Inácio Dias Ennes, Rodrigo Seiti Kojima, Nelson Hamerschlak
Journal: Blood (2023)
Prognostic Value of Ferritin in ASCT MM Patients: Integration with GEP Models and ISS Series Systems
Authors: Wancheng Guo, David E. Mery, Eric Siegel, Fumou Sun, Yan Cheng, Cody Ashby, Daisy V. Alapat, Hongling Peng, Samer Al Hadidi, Sharmilan Thanendrarajan, Carolina Schinke, Maurizio Zangari, Frits van Rhee, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan
Journal: Blood (2023)
Checkpoint Immunotherapy Is Associated with Preferential Activation of Tumor-Antigen Specific CD4 + T Cells in MDS
Authors: Elizabeth A. Griffiths, Pragya Srivastava, Eduardo Cortes Gomez, Junko Matsuzaki, Kunle Odunsi, Laura W Dillon, Devdeep Mukherjee, Christopher S. Hourigan, Jacqueline Peng, Shovik Bandyopadhyay, Kai Tan, Krista Belko, Amanda C. Przespolewski, Eunice S. Wang, Prashant Singh, Jianmin Wang, Michael J. Nemeth
Journal: Blood (2023)
Addition of Acalabrutinib to Lenalidomide and Rituximab Induces High Complete Response Rates in Patients with Previously Untreated Follicular Lymphoma: Results of a Phase II Study
Authors: Paolo Strati, Lei Feng, Jason Westin, Ranjit Nair, Luis Fayad, Maria Alma Rodriguez, Dai Chihara, Luis Malpica, Jared Henderson, Mariana Gallardo, Mario L. Marques-Piubelli, Polina Turova, Aleksandr Zaitsev, Iris Wang, Christopher R. Flowers, Loretta J. Nastoupil, Sattva S. Neelapu
Journal: Blood (2023)
A New Class of Synthetic Type-B Polycyclic Polyprenylated Acylphloroglucinols (PPAP-B) Overcomes Venetoclax-Resistance in Acute Myeloid Leukemia (AML)
Authors: Leonie Elisabeth Kampa, Anton Bleisch, Philipp Peslalz, Marcus Matthias Schittenhelm, Bernd Plietker, Kerstin Maria Kampa-Schittenhelm
Journal: Blood (2023)
A First-in-Human, Open-Label, Phase I Dose Escalation Trial of Daily Oral Nmt Inhibitor Zelenirstat in Patients with Relapsed/Refractory B-Cell Lymphomas and Advanced Solid Tumors
Authors: Randeep Sangha, Rahima Jamal, Jennifer Spratlin, John Kuruvilla, Laurie H. Sehn, Michael Weickert, Luc Berthiaume, John Robert Mackey
Journal: Blood (2023)
Optimizing Siglec-8-Directed Immunotherapy for Eosinophilic and Mast Cell Disorders
Authors: Jenny Huo, George S. Laszlo, Sheryl Y. T. Lim, Frances M. Cole, Allie R. Kehret, Junyang Li, Margaret C. Lunn, Jasmyn L. Persicke, Peter B. Rupert, Roland K. Strong, Roland B. Walter
Journal: Blood (2023)
Activin-a Increases B-Cell Acute Lymphoblastic Leukemia (B-ALL) Vesiculation and Modifies the Micro-RNA Cargo: Special Focus on MiR-491-5p
Authors: Eugenia Licari, Giulia Cricrì, Francesca Raimondo, Alice Martina Giussani, Marina Pitto, Carmelo Rizzari, Andrea Biondi, Valentina Bollati, Erica Dander, Giovanna D'Amico
Journal: Blood (2023)
Using Next Generation Sequencing of Flow Cytometry CD Markers and Machine Learning As a Replacement to Flow Cytometry Analysis for the Diagnosis of Hematologic Neoplasms
Authors: Maher Albitar, Hong Zhang, Andrew Ip, Wanlong Ma, James McCloskey, Katherine Linder, Jeffrey Justin Estella, Jamie Koprivnikar, Noa Biran, David S. Siegel, Ahmad Charifa, Arash Mohtashamian, Andrew L Pecora, Andre Goy
Journal: Blood (2023)
Excellent PFS and OS of Newly Diagnosed Multiple Myeloma Patients Receiving Carfilzomib, Bendamustine, and Dexamethasone (KBD): A 6.5 Year Follow-up
Authors: Michael Sang Hughes, Siyang Leng, Rajshekhar Chakraborty, Divaya Bhutani, Markus Mapara, Shahzad Raza, Suzanne Lentzsch
Journal: Blood (2023)
LSD1 Inhibition Synergizes with Venetoclax in Acute Myeloid Leukemia By Targeting Cellular Metabolism
Authors: Kanwaldeep Singh, Emily Hartung, Christina Muhs, Islam Alshamleh, Monisha Divakaran, Anna Dvorkin-Gheva, Sara Pishyar, Pradhariny Prabagaran, Dina Khalaf, Alejandro Garcia-Horton, Stephen Ronan Foley, Brian Leber, Irwin Walker, Kylie Lepic, Harald Schwalbe, Hubert Serve, Maria Kleppe, Hugh Young Rienhoff, Tobias Berg
Journal: Blood (2023)
Cutaneous T-Cell Lymphoma and Dupilumab Use: A Retrospective Matched Cohort Study of Clinical Characteristics and Treatment Outcomes
Authors: Robert Stuver, Stephen Dusza, Zachary D. Epstein-Peterson, Paola Ghione, William Johnson, Alison Moskowitz, Patricia Myskowski, Melissa Pulitzer, Steven M. Horwitz, Shamir Geller
Journal: Blood (2023)
How Induction Cycles before Remission Influence Long-Term Survival in Acute Myeloid Leukemia
Authors: Feng Zhu, Nianci Chen, Yile Zhou, Yi Zhang, Jian Huang, Wanzhuo Xie, Haitao Meng, Wen-Juan Yu, Liping Mao, Wenyuan MAI, Chunmei Yang, Juying Wei, Yinjun Lou, Min Yang, Jiejing Qian, Gaixiang Xu, De Zhou, Liya Ma, Xingnong Ye, Yanling Ren, Hongyan Tong, Huafeng Wang, Jie Jin
Journal: Blood (2023)
Results of a Phase 1/2 Study of Lower Dose CPX-351 for Patients with Int-2 or High Risk IPSS Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia after Failure to Hypomethylating Agents
Authors: Guillermo Montalban-Bravo, Elias Jabbour, Kelly S. Chien, Gautam Borthakur, Zeev Estrov, Tapan M. Kadia, Farhad Ravandi, Naveen Pemmaraju, Graciela Nogueras-Gonzalez, Heather Schneider, Rosmy John, Meghan Anne Meyer, Hagop M. Kantarjian, Guillermo Garcia-Manero, Xiao Qin DONG
Journal: Blood (2023)
A Single Bout of Exercise Enhances the Efficacy of Rituximab Against Autologous Chronic Lymphocytic Leukaemia B Cells <i>Ex Vivo</i> By Transiently Increasing Natural Killer Cell Frequency in Blood, and Simultaneously Mobilises CD5 +CD19 +CD20 + B Cells into Blood
Authors: Harrison D Collier-Bain, Annabelle Emery, Adam J Causer, Frankie F Brown, Rebecca Oliver, David Dutton, Josephine Crowe, Daniel Augustine, John Graby, Shoji Leach, Rachel Eddy, Daniela Rothschild Rodriguez, Juliet C Gray, Mark S Cragg, Kirstie L Cleary, Sally Moore, James Murray, James E Turner, John P Campbell
Journal: Blood (2023)
Hsa-LINC02418/mmu-4930573I07Rik regulated by METTL3 dictates anti-PD-L1 immunotherapeutic efficacy via enhancement of Trim21-mediated PD-L1 ubiquitination
Authors: Zhijia Sun, Haixing Mai, Chunyuan Xue, Zhongyi Fan, Jiangbo Li, Hairui Chen, Nan Huo, Xiaofeng Kang, Chuanhao Tang, Liaoxin Fang, Hui Zhao, Yuchen Han, Chao Sun, Huanyan Peng, Yimeng Du, Jing Yang, Nan Du, Xiaojie Xu
Journal: Journal for ImmunoTherapy of Cancer (2023)

Background Limited response to programmed death ligand-1 (PD-L1)/programmed death 1 (PD-1) immunotherapy is a major hindrance of checkpoint immunotherapy in non-small cell lung cancer (NSCLC). The abundance of PD-L1 on the tumor cell surface is crucial for the responsiveness of PD-1/PD-L1 immunotherapy. However, the negative control of PD-L1 expression and the physiological significance of the PD-L1 inhibition in NSCLC immunotherapy remain obscure. Methods Bioinformatics analysis was performed to profile and investigate the long non-coding RNAs that negatively correlated with PD-L1 expression and positively correlated with CD8+T cell infiltration in NSCLC. Immunofluorescence, in vitro PD-1 binding assay, T cell-induced apoptosis assays and in vivo syngeneic mouse models were used to investigate the functional roles of LINC02418 and mmu-4930573I07Rik in regulating anti-PD-L1 therapeutic efficacy in NSCLC. The molecular mechanism of LINC02418-enhanced PD-L1 downregulation was explored by immunoprecipitation, RNA immunoprecipitation (RIP), and ubiquitination assays. RIP, luciferase reporter, and messenger RNA degradation assays were used to investigate the m6A modification of LINC02418 or mmu-4930573I07Rik expression. Bioinformatics analysis and immunohistochemistry (IHC) verification were performed to determine the significance of LINC02418, PD-L1 expression and CD8+T cell infiltration. Results LINC02418 is a negative regulator of PD-L1 expression that positively correlated with CD8+T cell infiltration, predicting favorable clinical outcomes for patients with NSCLC. LINC02418 downregulates PD-L1 expression by enhancing PD-L1 ubiquitination mediated by E3 ligase Trim21. Both hsa-LINC02418 and mmu-4930573I07Rik (its homologous RNA in mice) regulate PD-L1 therapeutic efficacy in NSCLC via Trim21, inducing T cell-induced apoptosis in vitro and in vivo . Furthermore, METTL3 inhibition via N6-methyladenosine (m6A) modification mediated by YTHDF2 reader upregulates hsa-LINC02418 and mmu-4930573I07Rik. In patients with NSCLC, LINC02418 expression is inversely correlated with PD-L1 expression and positively correlated with CD8+T infiltration. Conclusion LINC02418 functions as a negative regulator of PD-L1 expression in NSCLC cells by promoting the degradation of PD-L1 through the ubiquitin-proteasome pathway. The expression of LINC02418 is regulated by METTL3/YTHDF2-mediated m6A modification. This study illuminates the underlying mechanisms of PD-L1 negative regulation and presents a promising target for improving the effectiveness of anti-PD-L1 therapy in NSCLC.
Peptidyl Arginine Deiminase (PAD) 4 Modulates the GI Microbiome and Baseline Inflammation in Mice: Implications for Sepsis
Authors: Veronica Bochenek, Nate Levine, Anh T.P. Ngo, Samir Maarouf, Abigail E Skidmore, M. Anna Kowalska, Caroline Diorio, Zachary Martinez, Mortimer Poncz, Kandace Gollomp
Journal: Blood (2023)
Validation of an Automated, Scalable Comprehensive Genomic Profiling Assay for Hematologic Malignancies
Authors: Grant Hogg, Tong Liu, Yuanyu (Helen) Cao, Adib Shafi, Ashraf Shabaneh, John Howitt, Amanda Williamson, Rachel Dango, Xiaojun Guan, Heidi Hoffmann, Michael Mooney, John Pruitt, Scott Parker, Henry Y. Dong, Stanley Letovsky, Li Cai, Shakti Ramkissoon, Anjen Chenn, Marcia Eisenberg, Eyad Almasri, Taylor Jacob Jensen
Journal: Blood (2023)
Cutaneous squamous cell carcinoma tumor accrual rates in immunosuppressed patients with autoimmune and inflammatory conditions: A retrospective cohort study
Authors: Emily E. Granger, Morgan Groover, Catherine Harwood, Charlotte M. Proby, Emily Karn, Fadi Murad, Chrysalyne D. Schmults, Emily S. Ruiz
Journal: Journal of the American Academy of Dermatology (2023)
The Role of Radiotherapy in Patients with Refractory Hodgkin Lymphoma after Brentuximab Vedotin and -/or Immune Checkpoint Inhibitors
Authors: Ting-Bo Liu, Xiaofan Li, Rui-Zhi Zhao, Han Shao, Gui-Qing Shi, Yan-Yan Qiu, Tian-Lan Tang, Yu-Ping Lin, Si-Lin Chen, Cheng Huang, Si-Qin Liao, Jin-Hua Chen, Hai-Ying Fu, Jian-Zhi Liu, Jian-Zhen Shen, Ben-Hua Xu, Yu-jing Zhang, Yong Yang
Journal: Blood (2023)
Discovery of JNJ-88549968, a Novel, First-in-Class CALRmutxCD3 T-Cell Redirecting Antibody for the Treatment of Myeloproliferative Neoplasms
Authors: Anna Kuchnio, Elsie Samakai, Eva Hug, Meritxell Balmaña, Lut Janssen, Ricardo Amorim, Ivo Cornelissen, Andrea Majoros, Michaël Broux, Isha Taneja, Vince Torti, Azra Agic, Stefan Moritsch, Filippo Benedetti, Felix Rosebrock, Kathryn Packman, Janine Arts, Sonal Patel, Oliver Christopher Lomas, M. Phillip Deyoung, Oleh Zagrijtschuk, Yusri Elsayed, Stefan Constantinescu, Robert Kralovics, Ulrike Philippar
Journal: Blood (2023)
Efficacy and Safety of Dapsone in Primary Immune Thrombocytopenia. Results of a Randomized, Placebo-Controlled Multicenter Trial and of a Single-Arm, Emulated Trial in the Prospective, Multicenter Carmen-France Registry
Authors: Marion Larue, Guillaume Moulis, Manuela Rueter, Sylvain Audia, Louis Terriou, Jean-Francois Viallard, Brigitte Pan Petesch, Bruno Royer, Bernard Bonnotte, Lionel Galicier, Olivier Lambotte, Francois Lefrere, Stephane Cheze, Mikael Ebbo, Orianne Wagner-Ballon, Matthieu Mahevas, Bertrand Godeau, Marc Michel
Journal: Blood (2023)
Development of a New CAR-T-Cell Therapy Targeting an Immune Checkpoint for Effective Treatment of Solid and Liquid Tumors
Authors: Toshiki Ochi, Yuko Matsuoka, Tatsuya Konishi, Masaki Maruta, Yukihiro Miyazaki, Kazushi Tanimoto, Masaki Yasukawa, Masakatsu Yamashita, Katsuto Takenaka
Journal: Blood (2023)
Relative Prognostic Value of Flow Cytometric Measurable Residual Disease before Allogeneic Hematopoietic Cell Transplantation for Adults with MDS/AML or AML
Authors: Corentin Orvain, Naveed Ali, Megan Othus, Eduardo Rodríguez-Arbolí, Filippo Milano, Brenda M. Sandmaier, Bart L. Scott, Frederick R. Appelbaum, Roland B. Walter
Journal: Blood (2023)
Acute Myeloid Leukemia in Elderly, Unfit Patients: Analysis of Turkish AML Prospective Registry Database, on Behalf of Acute Leukemia Working Group of Turkish Society of Hematology
Authors: Selin Merih Urlu, Guldane Cengiz Seval, Elçin Erdogan Yücel, Ozgur Mehtap, Emel Merve Yenihayat, Merve Gokcen Polat, Umit Yavuz Malkan, Demircan Ozbalci, Sureyya Yigit Kaya, Salih Sertac Durusoy, Aydan Akdeniz, Onur Kirkizlar, Ali Dogan, Ibrahim Ethem Pinar, Murat Kacmaz, Hacer Berna Afacan Ozturk, Unal Atas, Burak Deveci, Gulten Korkmaz Akat, Zeynep Tugba Guven, Omur Gokmen Sevindik, Fatih Demirkan, Inci Alacacioglu, Volkan Karakus
Journal: Blood (2023)
Selinexor, Daratumumab and Dexamethasone for Patients with Multiple Myeloma Previously Treated with Lenalidomide at First Relapse: A Real-World Study
Authors: Yingying Zhai, Lingzhi Yan, Song Jin, Jingjing Shang, Xiaolan Shi, Weiqin Yao, Zhi Yan, Shuang Yan, De-pei Wu, Chengcheng Fu
Journal: Blood (2023)
<i>ITGB1</i>-Expressing Effector Memory CD4 + T-Cell Response Associates with Clinical Recovery in Childhood Immune Thrombocytopenia
Authors: David E. Schmidt, Katja Heitink-Pollé, Benoit P Nicolet, Leendert Porcelijn, Marrie Bruin, C. Ellen Van der Schoot, Rick Kapur, Gestur Vidarsson, Masja De Haas
Journal: Blood (2023)
Dexamethasone is Associated with a Lower Incidence and Severity of Cytokine Release Syndrome Compared with Other Corticosteroid Regimens When Given as Premedication for Glofitamab Monotherapy in Patients with Relapsed/Refractory (R/R) Large B-Cell Lymphoma (LBCL)
Authors: Lorenzo Falchi, Carmelo Carlo-Stella, Franck Morschhauser, Michael Dickinson, Emmanuel Bachy, Guillaume Cartron, Cyrus Khan, Monica Tani, Joaquin Martinez-Lopez, Nancy L. Bartlett, Antonio Salar, Joshua Brody, Sirpa Leppä, Aurelien Berthier, Martine Kallemeijn, James Relf, Saibah Chohan, Linda Lundberg, Martin Hutchings
Journal: Blood (2023)
Targeting CDK8/CDK19 to Disrupt Leukemic Stem Cell-like Population in Acute Myeloid Leukemia: Exploring RVU120 As a Promising Frontline Therapy
Authors: Milena Mazan, Urszula Pakulska, Adrianna Moszyńska, Agnieszka Sroka-Porada, Krzysztof Tomasz Szade, Michał Mikula, Magdalena Kozakowska, Przemysław Juszczyński, Katarzyna Wiklik, Kristina Göller, Marta Obacz, Camille N. Abboud, Jan Maciej Zaucha, Ewa Lech Marańda, Noemi Angelosanto, Hendrik Nogai, Tomasz Rzymski
Journal: Blood (2023)
“Hermes” - Hemophilia Related Mental Illness: A Cross-Sectional, Multicenter Study in Switzerland
Authors: Francesca Schmitt, Laura Aliena Maier, Manuela Albisetti, Alice Trinchero, Lukas Graf, Heinz Hengartner, Pierre Fontana, Nicolas von der Weid, Katrin Scheinemann, Sylvia von Mackensen, Stefan Lerch, Corinna Reichl, Ines Mürner-Lavanchy, Johanna A. Kremer Hovinga, Michael Kaess, Mutlu Kartal-Kaess
Journal: Blood (2023)
Deletion 1p at Time of Diagnosis of Multiple Myeloma Portends Inferior Outcomes
Authors: Arti Vaishnav, Abdullah Khan, Qiuhong Zhao, Naresh Bumma, Francesca Cottini, Elvira Umyarova, Nidhi Sharma, Ashley E Rosko, Don Benson, Srinivas Devarakonda
Journal: Blood (2023)
The Efficacy and Safety of Zanubrutinib, Dexamethasone and or Not Cyclophosphamide Regimen in Symptomatic Waldenstrom Macroglobulinnemia
Authors: Aijun Liu, Jin Lu, Yanping Ma, Da Gao, Luoming Hua, Yuechen Zhang, Chuanying Geng, Ying Tian, Yun Leng, Wenming Chen
Journal: Blood (2023)