NCCN News
Journal: Journal of the National Comprehensive Cancer Network (2023)

New Resource From NCCN Breaks the Silence on Common but Lesser-Known Cause of Cancer Deaths NCCN announced the publication of a new supportive care patient guideline focused on preventing and treating cancer-associated blood clots, also known as venous thromboembolism (VTE).Research shows that people with cancer are 9 times more likely to experience blood clots than those without cancer.Blood clots are a leading cause of death for people with cancer, second only to the direct effects of the cancer itself. 1,2 The NCCN Guidelines for Patients: Blood Clots and Cancer are available to download for free at NCCN.org/patientguidelines, or via the NCCN Patient Guides for Cancer App, thanks to funding from the NCCN Foundation.Printed versions are available for a nominal fee at Amazon.com.These guidelines are based on the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Cancer-Associated Venous Thromboembolic Disease, the gold-standard resource that synthesizes the latest evidence and expert consensus to recommend the best options for patient care.These NCCN Guidelines are regularly updated by a multidisciplinary panel that includes cardiologists, radiologists, surgeons, pharmacists, and other cancer care professionals from leading centers across the country.Their recommendations are based on more than 600 peer-reviewed research articles.This new patient guideline puts NCCN's medical recomendations into easy-to-understand terms, including images, charts, and suggested questions to ask."We don't talk about blood clots enough in oncology, but we're getting better," said Michael B. Streiff, MD, Professor of Medicine, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Chair of the NCCN Guidelines Panel for Cancer-Associated Venous Thromboembolic Disease."Not only do tumors put people at risk for blood clots, but cancer treatments can also put people at risk.These patient guidelines will educate patients and caregivers about what we can do to prevent clotting, how to recognize the symptoms, and what treatments are available if they experience pulmonary embolism or deepvein thrombosis.""Cancer is a strong risk factor for developing a blood clot, and thrombosis is the second leading cause of death in patients with cancer.Yet, despite the known link between blood clots and cancer, there is still a lack of awareness about thrombosis risk in patients with cancer," noted Aviva Schwartz, MA, Director, Content and Education, North American Thrombosis Forum."It's critical to address this knowledge gap and encourage open conversations between patients and health care providers.These guidelines are an important step forward for patients with cancer and their family members and caregivers."According to Dr. Streiff, symptoms of blood clots can sometimes be vague or surprising.He noted that people with cancer should talk to their doctor about any changes in their body, particularly if they experience swelling, redness, deep muscle aches in the legs or arms, shortness of breath, chest pain, back pain, or lightheadedness.Risk assessment tools for VTE have advanced in recent years, helping doctors to understand which patients should proactively receive medications like anticoagulants (sometimes referred to as blood thinners), and also who should avoid them.The medications are evolving to be safer and easier to take.They are often available in pill form and are less likely to be associated with unwanted bleeding.