tbuckley/cabot-search huggingface dataset:
Structured early detection of compensated advanced chronic liver disease-results of the SEAL program
Authors: Christian Labenz, Anita Arslanow, Michael Nagel, Marc Nguyen-Tat, Marcus-Alexander Wörns, Matthias Reichert, Franz Josef Heil, Dagmar Mainz, Gudula Zimper, Barbara Römer, Johannes Jäger, Erik Farin-Glattacker, Urs Fichtner, Harald Binder, Erika Graf, Dominikus Stelzer, Reyn van Ewijk, Julia Ortne, Louis Velthuis, Frank Lammert, Peter Galle
Journal: Journal of Hepatology (2022)
Evidence of extensive transcriptionally active HBV integrations involving genetic regions crucial for cell proliferation in the setting of HBeAg positive infection
Authors: Romina Salpini, Luca Carioti, Arianna Battisti, Lorenzo Piermatteo, Livia Benedetti, Francesca Ceccherini Silberstein, Upkar Gill, Valentina Svicher, Patrick Kennedy
Journal: Journal of Hepatology (2022)
Dose-dependent durability of hepatitis B surface antigen reductions following administration of a single dose of VIR-3434, a novel neutralizing vaccinal monoclonal antibody
Authors: Kosh Agarwal, Man-Fung Yuen, Heiner Wedemeyer, Daniel Cloutier, Ling Shen, Andre Arizpe, Sneha V. Gupta, Marie C. Fanget, Lillian Seu, Andrea Cathcart, Audrey H. Lau, Carey Hwang, Edward J Gane
Journal: Journal of Hepatology (2022)
In silico characterization of the interactome of hepatic nonparenchymal cells reveals promising targets for antifibrotic therapy
Authors: Oleksandr Petrenko, Ksenia Brusilovskaya, Benedikt Hofer, Philipp Königshofer, Benedikt Simbrunner, Kaan Boztug, Michael Trauner, Philipp Schwabl, Thomas Reiberger
Journal: Journal of Hepatology (2022)
Reduction of intra-hepatic Z-AAT synthesis by fazirsiran decreases globule burden and improves histological measures of liver disease in adults with alpha-1 antitrypsin deficiency
Authors: Pavel Strnad, Mattias Mandorfer, Gourab Choudhury, Griffiths Bill, Christian Trautwein, Rohit Loomba, Romil Saxena, Thomas Schluep, Ting Chang, Min Yi, Bruce Given, James Hamilton, Javier San Martin, Jeffrey Teckman
Journal: Journal of Hepatology (2022)
Therapeutic suppression of HBV transcripts promotes reappearance of the SMC5/6 complex and cccDNA silencing in vivo without affecting posttranslational modifications of cccDNA-bound histones
Authors: Lena Allweiss, Moritz Calaminus, Katja Giersch, Tassilo Volz, Andrea Pirosu, Marc Luetgehetmann, Maura Dandri
Journal: Journal of Hepatology (2022)
Outcomes of a community led comprehensive HCV and HBV care provision model, including same-day “test and treat” to facilitate micro-elimination of HCV among people who inject drugs in Manipur, India
Authors: Khumukcham Lokeshwar Singh, Thangjam Dhabali, Rajkumari Rosie, Rajkumar Nalinikanta, Samurailatpam Rajesh Sharma, Sanjay Sarin, Giten Khwairakpam, Sonjelle Shilton
Journal: Journal of Hepatology (2022)
The prevalence and incidence of NAFLD worldwide: a systematic review and meta-analysis
Authors: Kiarash Riazi, Hassan Azhari, Jacob H Charette, Fox E Underwood, James A King, Elnaz Ehteshami Afshar, Mark G Swain, Stephen E Congly, Gilaad G Kaplan, Abdel-Aziz Shaheen
Journal: The Lancet. Gastroenterology & hepatology (2022)
Plasma cell-free DNA methylation as biomarker for hepatocellular carcinoma
Authors: María Gárate-Rascón, Miriam Recalde, Idoia Bilbao, Fabrice Daian, María Elizalde, María Azkona, José María Herranz, Carla Rojo, Mercedes Iñarrairaegui, Itziar Abete, María A. Zulet, Bruno Sangro, Maite G. Fernandez-Barrena, Loreto Boix, María Reig, Andrea Casadei Gardini, Matías A. Avila, Manuel F. Landecho, Carmen Berasain, Maria Arechederra
Journal: Journal of Hepatology (2022)
Everolimus combined with low-dose tacrolimus controls histological graft injury and liver fibrosis as sufficiently as high-dose tacrolimus combined with mycophenolate after liver transplantation
Authors: Fabian Dranicki, Emily Saunders, Theresa Kirchner, Bastian Engel, Björn Hartleben, Heiner Wedemeyer, Elmar Jaeckel, Richard Taubert
Journal: Journal of Hepatology (2022)
SVR4 and SVR12 monitoring by using dried blood spot test: is it the best alternative for people who use drugs?
Authors: Andrea Herranz, María Victoria Fernández-Baca, Maria Dolores Macia Romero, María Paz Díaz, Maria Carmen Gallegos Alvarez, Ricardo M Arcay, Francisco Salvà, Adoración Hurtado, Maria Buti, Àngels Vilella, Jeffrey Lazarus
Journal: Journal of Hepatology (2022)
Hepatic fat as a novel marker for high-risk coronary atherosclerosis in familial hypercholesterolaemia: a CT-based study
Authors: Gavin Huangfu, Biyanka Jaltotage, Jing Pang, Nick Lan, Arun Abraham, Jacobus Otto, Abdul Ihdayhid, Jamie Rankin, Benjamin Chow, Gerald Watts, Girish Dwivedi, Oyekoya Ayonrinde
Journal: Journal of Hepatology (2022)
In vivo CRISPR/Cas9 editing of the TTR gene with NTLA-2001 in patients with transthyretin amyloidosis- dose selection considerations
Authors: Edward J. Gane, Jörg Täubel, Björn Pilebro, Marianna Fontana, Justin Kao, Michael Maitland, Mark Stroh, Jessica Seitzer, Jonathan Phillips, Kristy Wood, Yuanxin Xu, Carri Boiselle, Adam Amaral, Adam Boyd, Jeffrey Cehelsky, David Gustein, Odelya Pagovich, Laura Sepp-Lorenzino, Liron Walsh, David Lebwohl, Gillmore Julian
Journal: Journal of Hepatology (2022)
Prognostic impact of variants in TM6SF2 and MBOAT7 in patients who have progressed to advanced chronic liver disease
Authors: Lorenz Balcar, Bernhard Scheiner, Markus Urheu, Patrick Weinberger, Rafael Paternostro, Benedikt Simbrunner, Georg Semmler, Nicole Auer, Claudia Willheim, Matthias Pinter, Michael Trauner, Thomas Reiberger, Mattias Mandorfer, Albert Stättermayer
Journal: Journal of Hepatology (2022)
Predictive survival-time modelling of Non-Alcoholic Steatohepatitis (NASH) fast progressors using real-world evidence
Authors: Nils Svangård, Christen Gray, Ally Taylor, Taylor Cohen, Bret Sellman, Claire Donoghue, Faisal Khan, Christopher Rhodes, Philip Ambery, Shameer Khader, John Dillon
Journal: Journal of Hepatology (2022)
Direct-acting antivirals and the risk of hepatitis B reactivation in hepatitis B and C coinfected patients: a systematic review and meta-analysis
Authors: Joo Hyun Oh, Sang Bong Ahn, Jeong-Ju Yoo, Dae Won Jun, Hyunwoo Oh, Huiyul Park, Joo Hyun Sohn, Hyo Young Lee, Bo-Kyeong Kang, Mi Mi Kim, Eileen Yoon, Chul-min Lee
Journal: Journal of Hepatology (2022)
Hepatocellular carcinoma and neutrophils-towards understanding positive and negative impacts on treatments and progression
Authors: João Maurício, Sandra Murphy, Misti McCain, Daniel Geh, Marcello Kadharusman, Jack Leslie, Robyn Watson, Steven Masson, Stuart Mcpherson, Alastair Burt, Ruchi Shukla, Derek A Mann, Caroline Wilson, Helen Louise Reeves
Journal: Journal of Hepatology (2022)
Hepatitis delta virus reflex testing in patients with hepatitis B improves the HDV screening cascade: 10 years of real-world experience from Avicenne University Hospital, France
Authors: Segolene Brichler, Dominique Roulot, Samira Dziri, Athenais Gerber, Frédéric Le Gal, Heloise Delagreverie, Chakib Alloui, Emmanuel Gordien
Journal: Journal of Hepatology (2022)
miR34a-5p is a target of E2F2 transcription factor in MAFLD-related HCC
Authors: Maider Apodaka-Biguri, Francisco Gonzalez-Romero, Daniela Mestre Congregado, Igor Aurrekoetxea, Beatriz Gómez Santos, Igotz Delgado, Xabier Buque, Ane Nieva-Zuluaga, Mikel Ruiz de Gauna, Idoia Fernámdez-Puertas, Ainhoa Iglesias, Ana María Aransay, Juanjo Lozano, Cesar Augusto Martín, Irantzu Bernales, Ana Zubiaga, Patricia Aspichueta
Journal: Journal of Hepatology (2022)
Impact of acute hepatic porphyria attack frequency on patient-reported outcomes: results from the porphyria worldwide patient experience research (POWER) study
Authors: Amy Dickey, Kristen Wheeden, Sue Burrell, Rocco Falchetto, Jasmin Barman-Aksözen, Alison Bulkley, Stephen Meninger, Stephen Lombardelli, Danielle Nance
Journal: Journal of Hepatology (2022)
Myosin Inhibition in Patients With Obstructive Hypertrophic Cardiomyopathy Referred for Septal Reduction Therapy
Authors: Milind Y. Desai, Anjali Owens, Jeffrey B. Geske, Kathy Wolski, Srihari S. Naidu, Nicholas G. Smedira, Paul C. Cremer, Hartzell Schaff, Ellen McErlean, Christina Sewell, Wanying Li, Lulu Sterling, Kathy Lampl, Jay M. Edelberg, Amy J. Sehnert, Steven E. Nissen
Journal: Journal of the American College of Cardiology (2022)

Septal reduction therapy (SRT), surgical myectomy or alcohol ablation, is recommended for obstructive hypertrophic cardiomyopathy (oHCM) patients with intractable symptoms despite maximal medical therapy, but is associated with morbidity and mortality. This study sought to determine whether the oral myosin inhibitor mavacamten enables patients to improve sufficiently to no longer meet guideline criteria or choose to not undergo SRT. Patients with left ventricular (LV) outflow tract (LVOT) gradient ≥50 mm Hg at rest/provocation who met guideline criteria for SRT were randomized, double blind, to mavacamten, 5 mg daily, or placebo, titrated up to 15 mg based on LVOT gradient and LV ejection fraction. The primary endpoint was the composite of the proportion of patients proceeding with SRT or who remained guideline-eligible after 16 weeks’ treatment. One hundred and twelve oHCM patients were enrolled, mean age 60 ± 12 years, 51% men, 93% New York Heart Association (NYHA) functional class III/IV, with a mean post-exercise LVOT gradient of 84 ± 35.8 mm Hg. After 16 weeks, 43 of 56 placebo patients (76.8%) and 10 of 56 mavacamten patients (17.9%) met guideline criteria or underwent SRT, difference (58.9%; 95% CI: 44.0%-73.9%; P < 0.001). Hierarchical testing of secondary outcomes showed significant differences (P < 0.001) favoring mavacamten, mean differences in post-exercise peak LVOT gradient −37.2 mm Hg; ≥1 NYHA functional class improvement 41.1%; improvement in patient-reported outcome 9.4 points; and NT-proBNP and cardiac troponin I between-groups geometric mean ratio 0.33 and 0.53. In oHCM patients with intractable symptoms, mavacamten significantly reduced the fraction of patients meeting guideline criteria for SRT after 16 weeks. Long-term freedom from SRT remains to be determined. (A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy [VALOR-HCM]; NCT04349072)
Associations between novel serum biomarkers chitinase-2-like protein (YKL-40), type IV collagen, and thrombospondin-2 (TSP-2) with fibrosis stage and clinical outcomes in patients with primary sclerosing cholangitis (PSC)
Authors: Michael Trauner, Andrew Muir, Jun Xu, Mina Khoshdeli, Bryan Downie, Andrew Billin, Chuhan Chung, Robert Myers, Zachary Goodman, Mitchell Shiffman, Harry Janssen, Aldo J Montano-Loza, Stephen Caldwell, Velimir Luketic, Michael P. Manns, Cynthia Levy, Christopher Bowlus
Journal: Journal of Hepatology (2022)
Editor's Note: Identification of Src-Specific Phosphorylation Site on Focal Adhesion Kinase: Dissection of the Role of Src SH2 and Catalytic Functions and Their Consequences for Tumor Cell Behavior
Authors: Valerie G. Brunton, Egle Avizienyte, Valerie J. Fincham, Bryan Serrels, Chester A. Metcalf, Tomi K. Sawyer, Margaret C. Frame
Journal: Cancer Research (2022)

The editors are publishing this note to alert readers to concerns about this article (1). We were informed by the authors that in Fig. 6A, the same image showing phospho-FAK tyr-925 staining was used in error in both Fig. 6M (Vector) and Fig. 6P (SrcMF).
Soluble guanylyl cyclase expression and signaling in different types of liver fibrosis
Authors: Ksenia Brusilovskaya, Philipp Königshofer, Benedikt Hofer, Oleksandr Petrenko, Kerstin Zinober, Martha Seif, Stefan Günther Kauschke, Larissa Pfisterer, Philipp Schwabl, Thomas Reiberger
Journal: Journal of Hepatology (2022)
Interleukin 10 and Interferon Gamma levels are elevated in patients with hepatocellular carcinoma showing response to treatment with atezolizumab and bevacizumab
Authors: Sabine Lieb, Aaron Schindler, Johannes Niemeyer, Rhea Veelken, Janett Fischer, Rami Al-Sayegh, Thomas Berg, Florian van Bömmel
Journal: Journal of Hepatology (2022)
Safety, pharmacokinetics and efficacy of the novel pan-phosphodiesterase inhibitor ZSP1601 in 36 NASH patients: a double-blinded, placebo-controlled, multiple-dose escalation phase Ib study
Authors: Yue Hu, Hai Jun Li, Hong Zhang, Jinjun Chen, Zhongyuan Xu, Hong You, Ruihua Dong, Xiaoxue Zhu, Hong Chen, Yun Peng, Jing Li, Xiaojiao Li, Lei Zhang, Di Cao, He Jin, Dongdong Qiu, Aruhan Yang, Jingrui Liu, Haiyan Jia, Jinfeng Lou, Junqi Niu, Yanhua Ding
Journal: Journal of Hepatology (2022)
Three-dimensional imaging of cleared human liver tissues reveals extensive fibrosis heterogeneity in non-alcoholic fatty liver disease
Authors: Buket Yigit, Ekin Ozgonul, Omer Yaman, Burge Ulukan, Yagmur Cetin Tas, Berna Morova, Musa Aydin, Yigit Uysalli, Elif Demirtas, Mert Erkan, Yasemin Gursoy Ozdemir, Sercin Karahuseyinoglu, Cihan Yurdaydin, Murat Akyildiz, Abhishek Sheth, Hale Kirimlioglu, Murat Dayangac, Onur Ferhanoglu, Alper Kiraz, Mujdat Zeybel
Journal: Journal of Hepatology (2022)
Relevance of diabetes medication on recruitment criteria for clinical studies in patients with non-alcoholic fatty disease and type 2 diabetes mellitus
Authors: Michael Holzhey, David Petroff, Valentin Blank, Florian Gerhardt, Albrecht Boehlig, Toni Herta, Florian van Bömmel, Thomas Berg, Thomas Karlas, Johannes Wiegand
Journal: Journal of Hepatology (2022)
Increased expression of programmed cell death ligand 1 and galectin 9 in transplant recipients who achieved tolerance after immunosuppression withdrawal
Authors: Nguyen Hai Nam, Kojiro Taura, Yukinori Koyama, Takahiro Nishio, Gen Yamamoto, Yusuke Uemoto, Yusuke Kimura, Li Xuefeng, Daichi Nakamura, Kenji Yoshino, Eri Ogawa, Tatsuya Okamoto, Atsushi Yoshizawa, Satoru Seo, Keiko Iwaisako, Tomoaki Yoh, Koichiro Hata, Toshihiko Masui, Hideaki Okajima, Hironori Haga, Shinji Uemoto, Etsuro Hatano
Journal: Journal of Hepatology (2022)
FOXA2 prevents hyperbilirubinemia through maintaining apical MRP2 expression in acute liver failure
Authors: Sai Wang, Rilu Feng, Shanshan Wang, Hui Liu, Chen Shao, Yujia Li, Frederik Link, Stefan Munker, Roman Liebe, Christoph Meyer, Elke Burgermeister, Matthias Ebert, Steven Dooley, Huiguo Ding, Honglei Weng
Journal: Journal of Hepatology (2022)
Clinical relevance of an animal model of non-alcoholic steatohepatitis (NASH) and digital pathology with artificial intelligence (DP-AI) analyses of hepatic fibrosis
Authors: Yishuang Wei, Mengnan Zhang, Jiliang Zhang, Xiao Teng, Qiang Yang, Alvin Leong, Gideon Ho, Henry Lu, Deming Xu
Journal: Journal of Hepatology (2022)
Genetics of liver fat and volume associate with altered metabolism and whole body magnetic resonance imaging
Authors: Shafqat Ahmad, Germán Carrasquilla, Taro Langner, Uwe Menzel, Filip Malmberg, Ulf Hammar, Jenny C. Censin, Sergi Sayols, Diem Nguyen, Andrés Martínez Mora, Jan W. Eriksson, Robin Strand, Joel Kullberg, Håkan Ahlström, Tove Fall
Journal: Journal of Hepatology (2022)
Safety and pharmacokinetics (PK) of single and multiple ascending oral doses of ALG-055009, a thyroid hormone receptor beta agonist for the treatment of non-alcoholic steatohepatitis (NASH), in healthy volunteers and subjects with hyperlipidemia
Authors: Hakim Charfi, Jean-Louis Pinquier, Benedetta Massetto, Kha Le, Christopher Westland, Kusum Gupta, Lawrence Blatt, Sushmita Chanda, John Fry, Matt McClure
Journal: Journal of Hepatology (2022)
Tumor Cells Modulate Macrophage Phenotype in a Novel In Vitro Co-Culture Model of the NSCLC Tumor Microenvironment
Authors: Josiah Voth Park, Raghav Chandra, Ling Cai, Debolina Ganguly, Huiyu Li, Jason E Toombs, Luc Girard, Rolf A Brekken, John D Minna
Journal: Journal of Thoracic Oncology (2022)
Non-invasive tools are suboptimal to predict the presence of varices needing treatment and risk of clinical decompensation in patients with autoimmune hepatitis related cirrhosis
Authors: Randeep Rana, Samagra Agarwal, Sanchit Sharma, Ujjwal Sonika, Syed Ahmed, Srikanth Gopi, Deepak Gunjan, Anoop Saraya
Journal: Journal of Hepatology (2022)
Renin/angiotensin system-coagulation-inflammation axis abnormalities: a possible explanation for susceptibility to severe COVID-19 in cirrhosis
Authors: Lukas Hartl, Mathias Jachs, Benedikt Simbrunner, David JM Bauer, Georg Semmler, Daniela Gompelmann, Thomas Szekeres, Peter Quehenberger, Michael Trauner, Mattias Mandorfer, Bernhard Scheiner, Thomas Reiberger
Journal: Journal of Hepatology (2022)
Characterization of circulating hepatitis B Virus RNAs in vitro and chronic hepatitis B patients
Authors: Doohyun Kim, Delphine Bousquet, Marie-Laure Plissonnier, Hyoseon Tak, Xavier Grand, Chloe Goldsmith, Françoise Berby, Bordes Isabelle, Alexia Paturel, Aaron Hamilton, Marintha Heil, Massimo Levrero, Barbara Testoni, Fabien Zoulim
Journal: Journal of Hepatology (2022)
Pruriceptor activating compounds in the eneterohepatic cycle in cholestatic itch
Authors: Frank Wolters, Jacqueline Langedijk, Dagmar Tolenaars, Michel van Weeghel, Rudi de Waart, Stan van de Graaf, Coen Paulusma, Wendy L. van der Woerd, Henkjan J. Verkade, Arthur Verhoeven, Ulrich Beuers, Ronald Oude Elferink
Journal: Journal of Hepatology (2022)
Effectiveness and safety of 8-week glecaprevir/pibrentasvir in HCV treatment naïve patients with compensated cirrhosis: real-world experience from Taiwan HCV registry
Authors: Chao-Hung Hung, Te-Sheng Chang, Chung-Feng Huang, Hsing-Tao Kuo, Ching-Chu Lo, Chien-Wei Huang, Lee-Won Chong, Pin-Nan Cheng, Ming-Lun Yeh, Cheng-Yuan Peng, Chien-Yu Cheng, Jee-Fu Huang, Ming-Jong Bair, Chih-Lang Lin, Chi-Chieh Yang, Sih-Ren Wang, Tsai-Yuan Hsieh, Tzong-Hsi Lee, Pei-Lun Lee, Wen-Chih Wu, Chih-Lin Lin, Wei-Wen Su, Shengshun Yang, Chia-Chi Wang, Jui-Ting Hu, Lien-Juei Mou, Chun-Ting Chen, Yi-Hsiang Huang, Chun-Chao Chang, Jia-Sheng Huang, Guei-Ying Chen, Jian-Neng Gao, Chi-Ming Tai, Chun-Jen Liu, Mei-Hsuan Lee, Pei-Chien Tsai, Chia-Yen Dai, Jia-Horng Kao, Han-Chieh Lin, Wan-Long Chuang, Chiyi Chen, Kuo-Chih Tseng, Ming-Lung Yu
Journal: Journal of Hepatology (2022)
Comparison of diagnostic performance between FIB-4 and NFS in metabolic-associated fatty liver disease era
Authors: Dae Won Jun, Eileen Yoon, Sang Bong Ahn, Huiyul Park, Hyo Young Lee, Hyunwoo Oh, Joo Hyun Sohn, Bo-Kyeong Kang, Mi Mi Kim, Chul-min Lee
Journal: Journal of Hepatology (2022)
Liver resection for single large hepatocellular carcinoma: a prognostic factors study
Authors: Giuliana Amaddeo, Vincent Nguyen-Khac, Rami Rhaiem, Vincent Leroy, Helene Regnault, Raffaele Brustia, Alexis Laurent, Françoise Roudot-Thoraval, Daniele Sommacale
Journal: Journal of Hepatology (2022)
Effectiveness of pangenotypic retreatment of HCV infection after prior failure of pangenotypic therapies
Authors: Robert Flisiak, Justyna Janocha-Litwin, Anna Parfieniuk-Kowerda, Dorota Zarębska-Michaluk, Marek Sitko, Piekarska Anna, Jolanta Białkowska, Dorota Dybowska, Witold Dobracki, Simon Krzysztof, Aleksandra Murawska-Ochab, Małgorzata Pawłowska
Journal: Journal of Hepatology (2022)
Increased expression of podoplanin, a marker of dilated lymphatic vessels in duodenal biopsies is an independent predictor of three-month mortality in patients with cirrhosis
Authors: Savneet Kaur, Pinky Juneja, S Muralikrishna Shasthry, Guresh Kumar, Dinesh Mani Tripathi, Vijayraghavan Rajan, Archana Rastogi, Shiv Kumar Sarin
Journal: Journal of Hepatology (2022)
Liver complications in greek patients with sickle cell disease: a multicenter retrospective analysis from eight thalassemia and sickle cell units across Greece
Authors: Konstantinos Manganas, Sophia Delicou, Aikaterini Xydaki, Alexandra Kourakli, Loukia Evliati, Euthimia Vlahaki, Evangelos Klironomos, Michail Diamantidis, Ioannis Lafiatis, Antonis Kattamis, Ioannis-Georgios Koskinas
Journal: Journal of Hepatology (2022)
In vivo loss-of-function studies unravel protein tyrosine phosphatase delta as a regulator of liver regeneration during metabolic liver disease
Authors: Armando Andres Roca Suarez, Laurent Mailly, Natascha Roehlen, Alessia Virzi, Nicolas Brignon, Frank Jühling, Christine Thumann, Sarah Durand, Marine Oudot, Eugénie Schaeffer, Romain Martin, Laura Heydmann, Charlotte Bach, Romain Parent, Carole Jamey, Daniel Brumaru, Nassim Dali-Youcef, Emanuele Felli, Patrick Pessaux, Atish Mukherji, Catherine Schuster, Thomas Baumert, Joachim Lupberger
Journal: Journal of Hepatology (2022)
Linear slope of serial FIB-4 measurements predicts liver-related complications and correlates with cirrhosis-associated genetic variants among patients with ALT-based NAFLD phenotype
Authors: Craig Teerlink, David E. Kaplan, Marijana Vujkovic, Benjamin Voight, Kyong-Mi Chang, Julie Lynch, Scott Duvall, Tori Anglin, Timothy Morgan, Linus Schwantes-An Tae-Hwi, Trina Norden-Krichmar, Daniel Dochterman, Poornima Devineni, Philip Tsao, Carolin Victoria Schneider
Journal: Journal of Hepatology (2022)
Liver stiffness predicts incident severe liver disease in patients with chronic liver disease
Authors: Hannes Hegmar, Axel Wester, Soo Aleman, Jens Backman, Erik Degerman, Håkan Ekvall, Katarina Lund, Åsa Lundgren, Patrik Nasr, Afshin Shahnavaz, Johan Vessby, Johan Westin, Kristina Önnerhag, Hannes Hagström
Journal: Journal of Hepatology (2022)
Circulating vesicles hold etiology-related protein biomarkers of cholangiocarcinoma risk, early diagnosis and prognosis mirroring tumour cells
Authors: Ainhoa Lapitz, Mikel Azkargorta, Ekaterina Zhuravleva, Marit M. Grimsrud, Colm O. Rourke, Ander Arbelaiz, Adelaida La Casta, Mette Vesterhus, Piotr Milkiewicz, Malgorzata Milkiewicz, Raul Jimenez-Aguero, Tania Pastor, Rocio IR Macias, Ioana Riaño, Laura Izquierdo-Sánchez, Marcin Krawczyk, Cesar Ibarra, Javier Bustamante, Felix Elortza, Juan Falcon-Perez, María Jesús Perugorria, Jesper Andersen, Luis Bujanda, Tom Hemming Karlsen, Trine Folseraas, Pedro Miguel Rodrigues, Jesus Maria Banales
Journal: Journal of Hepatology (2022)
The Comparison of tenofovir alafenamide fumarate with tenofovir disoproxil fumarate in preventing hepatitis B transmission in mothers with high viral load: a retrospective cohort study
Authors: Yunxia Zhu, Jinhua Wang, Ming Wang, Xin Zhou, Shuangxia Zhang, Shujie Zhang, Bo Yang, Ping Yang, Zhongjie Hu
Journal: Journal of Hepatology (2022)
Pretransplant changes in serum protein glycosylation relate to risk of HCC recurrence after liver transplantation and provide a potential prognostic biomarker: a proof-of-concept study
Authors: Xavier Verhelst, Heleen Engels, Anja Geerts, Aude Vanlander, Luis Abreu de Carvalho, Helena Degroote, Leander Meuris, Frederik Berrevoet, Nico Callewaert, Hans Van Vlierberghe
Journal: Journal of Hepatology (2022)
Management of hepatic sarcoidosis-multicentric approach
Authors: Janina Sollors, Andreas Teufel, Christoph Antoni, Matthias Ebert, Svetlana Hetjens, Yuquan Qian, Bernhard Schlevogt, Marcus-Alexander Woerns, Peter Galle, Cleo-Aron Weis, Raoul Bergner
Journal: Journal of Hepatology (2022)
Combination treatment of a PAPD5/7 inhibitor with an antisense oligonucleotide bepirovirsen with concurrent dosing shows additive HBsAg decreases in the AAV-HBV mouse model
Authors: Jared Delahaye, Edward Long, Chi Lau, Jacob Parsons, Bo Wen, Zhiyi Cui, Melanie Paff, Shihyun You, Martin Leivers
Journal: Journal of Hepatology (2022)
A nine-strain bacterial consortium improves portal hypertension and insulin signaling and delays non-alcoholic fatty liver disease progression in vivo
Authors: Iris Pinheiro, Aurora Barbera, Imma Raurell, Federico Estrella, Marcel de Leeuw, Selin Bolca, Davide Gottardi, Nigel Horscroft, Sam Possemiers, Maria Teresa Salcedo, Joan Genesca, María Martell, Salvador Augustin
Journal: Journal of Hepatology (2022)
Stable rates of cirrhosis diagnosed by Fibroscan despite changing trends in liver disease epidemiology: a single centre retrospective cohort study
Authors: Joan Ericka Flores, Anne Craigie, Lucy McDonald, Amy Edwards, Tim Papaluca, Michael MacIsaac, John Gough, Kate New, Susanne Glasgow, Bradley Whitton, Paul Desmond, Marno Ryan, Thai Hong, Zina Valaydon, Jacinta Holmes, Barbara Demediuk, Catherine Croagh, David Iser, Kumar Visvanathan, Swee Lin Chen Yi Mei, Alexander Thompson, Jessica Howell
Journal: Journal of Hepatology (2022)