tbuckley/cabot-search huggingface dataset:
Use of COVIDTests.gov At-Home Test Kits Among Adults in a National Household Probability Sample — United States, 2022
Authors: Nicole Luisi, Patrick S. Sullivan, Travis Sanchez, Heather Bradley, Mansour Fahimi, Kayoko Shioda, Kristin N. Nelson, Benjamin A. Lopman, Aaron J. Siegler
Journal: MMWR Morbidity and Mortality Weekly Report (2023)

At-home rapid antigen COVID-19 tests were first authorized by the Food and Drug Administration in late 2020 (1-3). In January 2022, the White House launched COVIDTests.gov, which made all U.S. households eligible to receive free-to-the-user at-home test kits distributed by the U.S. Postal Service (2). By May 2022, more than 70 million test kit packages had been shipped to households across the United States (2); however, how these kits were used, and which groups were using them, has not been reported. Data from a national probability survey of U.S. households (COVIDVu), collected during April-May 2022, were used to evaluate awareness about and use of these test kits (4). Most respondent households (93.8%) were aware of the program, and more than one half (59.9%) had ordered kits. Among persons who received testing for COVID-19 during the preceding 6 months, 38.3% used a COVIDTests.gov kit. Among kit users, 95.5% rated the experience as acceptable, and 23.6% reported being unlikely to have tested without the COVIDTests.gov program. Use of COVIDTests.gov kits was similar among racial and ethnic groups (42.1% non-Hispanic Black or African American [Black]; 41.5% Hispanic or Latino [Hispanic]; 34.8% non-Hispanic White [White]; and 53.7% non-Hispanic other races [other races]). Use of other home COVID-19 tests differed by race and ethnicity (11.8% Black, 44.4% Hispanic, 45.8% White, 43.8% other races). Compared with White persons, Black persons were 72% less likely to use other home test kits (adjusted relative risk [aRR] = 0.28; 95% CI = 0.16-0.50). Provision of tests through this well-publicized program likely improved use of COVID-19 home testing and health equity in the United States, particularly among Black persons. National programs to address availability and accessibility of critical health services in a pandemic response have substantial health value.
Is Appendiceal Cancer a Lynch Syndrome–Associated Cancer?
Authors: Matthew B. Yurgelun, David J. Papke, Mark S. Redston
Journal: JAMA Oncology (2023)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Oncology HomeNew OnlineCurrent IssueFor Authors Podcast Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Oncology journal
Influence of racial and ethnic identity on overall survival in patients with chronic lymphocytic leukemia
Authors: Victoria A. Vardell, Daniel A. Ermann, Lindsey A. Fitzgerald, Harsh R. Shah, Boyu Hu, Deborah M. Stephens
Journal: American Journal of Hematology (2023)

Overall survival for chronic lymphocytic leukemia (CLL) patients by race; propensity score matched by age, Charlson-Deyo comorbidity score, insurance, and income and education level of zip code of residence.
Cerebrospinal fluid: The new frontier for methylome-based diagnostic classification of brain tumors
Authors: Alexandra M Miller, Matthias A Karajannis
Journal: Neuro-Oncology (2023)

Journal Article Cerebrospinal fluid: The new frontier for methylome-based diagnostic classification of brain tumors Get access Alexandra M Miller, Alexandra M Miller Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, USADepartment of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, USA Corresponding Author: Alexandra M. Miller, MD, PhD, Department of Neurology and Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA (millera2@mskcc.org). Search for other works by this author on: Oxford Academic PubMed Google Scholar Matthias A Karajannis Matthias A Karajannis Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, USA https://orcid.org/0000-0002-7151-6528 Search for other works by this author on: Oxford Academic PubMed Google Scholar Neuro-Oncology, Volume 25, Issue 8, August 2023, Pages 1461–1462, https://doi.org/10.1093/neuonc/noad075 Published: 20 April 2023 Article history Published: 20 April 2023 Corrected and typeset: 09 May 2023
COVID-19 outbreaks among crew on commercial ships at the Port of Rotterdam, the Netherlands, 2020 to 2021
Authors: Edward Gebuis, Bruno Vieyra, Rob Slegtenhorst, Saskia Wiegmans, Bas van Dijk, Thijs Veenstra, Saskia Tejland, Ewout Fanoy, Annemieke de Raad, Marion Koopmans, René de Vries, Saskia van Leeuwen-Voerman, Jane Whelan
Journal: Eurosurveillance (2023)

BackgroundDuring the COVID-19 pandemic, international shipping activity was disrupted as movement of people and goods was restricted. The Port of Rotterdam, the largest port in Europe, remained operational throughout.AimWe describe the burden of COVID-19 among crew on sea-going vessels at the port and recommend improvements in future infectious disease event notification and response at commercial ports.MethodsSuspected COVID-19 cases on sea-going vessels were notified to port authorities and public health (PH) authorities pre-arrival via the Maritime Declaration of Health. We linked data from port and PH information systems between 1 January 2020 and 31 July 2021, derived a notification rate (NR) of COVID-19 events per arrival, and an attack rate (AR) per vessel (confirmed cases). We compared AR by vessel type (workship/tanker/cargo/passenger), during wildtype-, alpha- and delta-dominant calendar periods.ResultsEighty-four COVID-19 events were notified on ships, involving 622 cases. The NR among 45,030 new arrivals was 173 per 100,000 impacting 1% of vessels. Events per week peaked in April 2021 and again in July 2021, when the AR was also highest. Half of all cases were notified on workships, events occurring earlier and more frequently than on other vessels.ConclusionNotification of COVID-19 events on ships occurred infrequently, although case under-ascertainment was likely. Pre-agreed protocols for data-sharing between stakeholders locally and across Europe would facilitate more efficient pandemic response. Public health access to specimens for sequencing and environmental sampling would give greater insight into viral spread on ships.
ZDHHC2-mediated AGK palmitoylation activates AKT/mTOR signaling to reduce sunitinib sensitivity in renal cell carcinoma
Authors: Yan Sun, Liang Zhu, Pian Liu, Huan Zhang, Feng Guo, Xin Jin
Journal: Cancer Research (2023)

Abstract Tyrosine kinase inhibitors (TKI) that can suppress the VEGF signaling pathway and angiogenesis have been developed to impede the progression of malignant tumors and have been approved as first-line targeted agents for clear cell renal cell carcinoma (ccRCC). Dysregulation of lipid metabolism is a major driver of TKI resistance in renal cancer. In this study, we showed that the palmitoyl acyltransferase ZDHHC2 is abnormally upregulated in tissues and cell lines resistant to TKIs, such as sunitinib. Upregulation of ZDHHC2 contributed to sunitinib resistance in cells and mice, and ZDHHC2 regulated angiogenesis and cell proliferation in ccRCC. Mechanistically, ZDHHC2 mediated AGK S-palmitoylation to promote translocation of AGK into the plasma membrane and activation of the PI3K–AKT–mTOR signaling pathway in ccRCC, which modulated sunitinib sensitivity. In conclusion, these results identify a ZDHHC2–AGK signaling axis and suggest that ZDHHC2 is a targetable candidate for improving the antitumor efficacy of sunitinib in ccRCC. Significance: ZDHHC2 confers sunitinib resistance to clear cell renal cell carcinoma by catalyzing AGK palmitoylation to activate the AKT–mTOR pathway.
Suspected Suicide Attempts by Self-Poisoning Among Persons Aged 10–19 Years During the COVID-19 Pandemic — United States, 2020–2022
Authors: Rita Farah, Saumitra V. Rege, Ryan J. Cole, Christopher P. Holstege
Journal: MMWR Morbidity and Mortality Weekly Report (2023)

The World Health Organization declared COVID-19 a global pandemic on March 11, 2020 (1). As strategies to mitigate the pandemic were implemented, concerns were raised that the containment efforts through quarantine and social distancing practices were negatively affecting the mental and physical health of children and adolescents (2). Suicide is a growing public health problem in the United States. In 2020, suicide was the second leading cause of death among persons aged 10-14 years and the third leading cause among those aged 15-24 years (3). The National Poison Data System (NPDS) database was used to examine trends in suspected suicide attempts by self-poisoning among persons aged 10-19 years before and during the COVID-19 pandemic. Compared with 2019 (prepandemic), during 2021, the overall rate of suspected suicide attempts by self-poisoning increased by 30.0% (95% CI = 28.6%-30.9%), rates among children aged 10-12 years, adolescents aged 13-15 years, and females increased 73.0% (67.4%-80.0%), 48.8% (46.7%-50.9%), and 36.8% (35.4%-38.2%), respectively, and these trends continued into the third quarter of 2022. Substances most frequently involved in overdoses were acetaminophen, ibuprofen, sertraline, fluoxetine, and diphenhydramine. Acetaminophen-involved overdoses increased 71% (67.4%-74.9%) in 2021 and 58.0% (54.5%-61.6%) in 2022. Diphenhydramine-involved overdoses increased 24.2% (19.9%-28.7%) in 2021 and 35.8% (31.2%-40.5%) in 2022. A comprehensive public health approach to suicide prevention, focused on children and adolescents and involving a partnership between families, school teachers, mental health professionals, and public health leadership is needed. The 9-8-8 Suicide and Crisis Lifeline provides crisis support for persons experiencing mental health-related distress and assists community members who are concerned about persons experiencing a mental health crisis.
Epidemic intelligence data of Crimean-Congo haemorrhagic fever, European Region, 2012 to 2022: a new opportunity for risk mapping of neglected diseases
Authors: Angela Fanelli, Johannes Christof Schnitzler, Marco De Nardi, Alastair Donachie, Ilaria Capua, Gianvito Lanave, Domenico Buonavoglia, Paula Caceres-Soto, Paolo Tizzani
Journal: Eurosurveillance (2023)

BackgroundThe Epidemic Intelligence from Open Sources (EIOS) system, jointly developed by the World Health Organisation (WHO), the Joint Research Centre (JRC) of the European Commission and various partners, is a web-based platform that facilitate the monitoring of information on public health threats in near real-time from thousands of online sources.AimsTo assess the capacity of the EIOS system to strengthen data collection for neglected diseases of public health importance, and to evaluate the use of EIOS data for improving the understanding of the geographic extents of diseases and their level of risk.MethodsA Bayesian additive regression trees (BART) model was implemented to map the risk of Crimean-Congo haemorrhagic fever (CCHF) occurrence in 52 countries and territories within the European Region between January 2012 and March 2022 using data on CCHF occurrence retrieved from the EIOS system.ResultsThe model found a positive association between all temperature-related variables and the probability of CCHF occurrence, with an increased risk in warmer and drier areas. The highest risk of CCHF was found in the Mediterranean basin and in areas bordering the Black Sea. There was a general decreasing risk trend from south to north across the entire European Region.ConclusionThe study highlights that the information gathered by public health intelligence can be used to build a disease risk map. Internet-based sources could aid in the assessment of new or changing risks and planning effective actions in target areas.
Myocardial Injury Thresholds for 4 High-Sensitivity Troponin Assays in a Population-Based Sample of US Children and Adolescents
Authors: John W. McEvoy, Dan Wang, Tammy Brady, Olive Tang, Chiadi E. Ndumele, Josef Coresh, Robert H. Christenson, Elizabeth Selvin
Journal: Circulation (2023)

Myocardial injury is an important pediatric diagnosis. Establishing normative data from a representative pediatric sample is vital to provide accurate upper reference limits (URLs) for defining myocardial injury using high-sensitivity cardiac troponin.
Cryptic SARS-CoV-2 lineage identified on two mink farms as a possible result of long-term undetected circulation in an unknown animal reservoir, Poland, November 2022 to January 2023
Authors: Katarzyna Domańska-Blicharz, Bas B Oude Munnink, Anna Orłowska, Marcin Smreczak, Justyna Opolska, Anna Lisowska, Paweł Trębas, Wojciech Socha, Aleksandra Giza, Arkadiusz Bomba, Ewelina Iwan, Jerzy Rola, Marion Koopmans
Journal: Eurosurveillance (2023)

In late 2022 and early 2023, SARS-CoV-2 infections were detected on three mink farms in Poland situated within a few km from each other. Whole-genome sequencing of the viruses on two of the farms showed that they were related to a virus identified in humans in the same region 2 years before (B.1.1.307 lineage). Many mutations were found, including in the S protein typical of adaptations to the mink host. The origin of the virus remains to be determined.
Stereotactic Radiosurgery vs Conventional Radiotherapy for Localized Vertebral Metastases of the Spine
Authors: Samuel Ryu, Snehal Deshmukh, Robert D. Timmerman, Benjamin Movsas, Peter Gerszten, Fang-Fang Yin, Adam Dicker, Christopher D. Abraham, Jim Zhong, Stephen L. Shiao, Richard Tuli, Anand Desai, Loren K. Mell, Puneeth Iyengar, Ying J. Hitchcock, Aaron Max Allen, Steven Burton, Doris Brown, Hadley J. Sharp, Neal E. Dunlap, M. Salim Siddiqui, Timothy H. Chen, Stephanie L. Pugh, Lisa A. Kachnic
Journal: JAMA Oncology (2023)

Spine metastasis can be treated with high-dose radiation therapy with advanced delivery technology for long-term tumor and pain control.
Lipoprotein(a) and calcific aortic valve disease initiation and progression: a systematic review and meta-analysis
Authors: Panteleimon Pantelidis, Evangelos Oikonomou, Stamatios Lampsas, Georgios E Zakynthinos, Antonios Lysandrou, Konstantinos Kalogeras, Efstratios Katsianos, Panagiotis Theofilis, Gerasimos Siasos, Michael Andrew Vavuranakis, Alexios S Antonopoulos, Dimitris Tousoulis, Manolis Vavouranakis
Journal: Cardiovascular Research (2023)

Abstract Although evidence indicates the association of lipoprotein(a) [Lp(a)] with atherosclerosis, the link with calcific aortic valve disease (CAVD) is unclear. This systematic review and meta-analysis explores the connection between Lp(a) and aortic valve calcification and stenosis (AVS). We included all relevant studies, indexed in eight databases, up to February 2023. A total of 44 studies (163 139 subjects) were included, with 16 of them being further meta-analysed. Despite considerable heterogeneity, most studies support the relationship between Lp(a) and CAVD, especially in younger populations, with evidence of early aortic valve micro-calcification in elevated-Lp(a) populations. The quantitative synthesis showed higher Lp(a) levels, by 22.63 nmol/L (95% CI: 9.98–35.27), for patients with AVS, while meta-regressing the data revealed smaller Lp(a) differences for older populations with a higher proportion of females. The meta-analysis of eight studies providing genetic data, revealed that the minor alleles of both rs10455872 and rs3798220 LPA gene loci were associated with higher risk for AVS (pooled odds ratio 1.42; 95% CI: 1.34–1.50 and 1.27; 95% CI: 1.09–1.48, respectively). Importantly, high-Lp(a) individuals displayed not only faster AVS progression, by a mean difference of 0.09 m/s/year (95% CI: 0.09–0.09), but also a higher risk of serious adverse outcomes, including death (pooled hazard ratio 1.39; 95% CI: 1.01–1.90). These summary findings highlight the effect of Lp(a) on CAVD initiation, progression and outcomes, and support the early onset of Lp(a)-related subclinical lesions before clinical evidence.
Home is where the liver is?: Moving beyond readmissions to time at home as a patient-centered and pragmatic quality measure in cirrhosis care
Authors: Nneka N. Ufere
Journal: Hepatology (2023)

Funding/Support: American Association for the Study of Liver Diseases Clinical, Translational, and Outcomes Research Award (NNU), Massachusetts General Hospital Physician Scientist Development Award (NNU), Cambia Health Foundation Sojourns Scholar Leadership Program Award (NNU). None of the sponsors had any role in the design and conduct of the study. Correspondence Nneka N. Ufere, Liver Center, Gastrointestinal Unit, Department of Medicine Massachusetts General Hospital 55 Fruit Street, Boston, MA 02114. Email: [email protected]
Association of Mental Health Conditions, Recent Stressful Life Events, and Adverse Childhood Experiences with Postpartum Substance Use ― Seven States, 2019–2020
Authors: Andrea Stewart, Jean Ko, Beatriz Salvesen von Essen, Madison Levecke, Denise V. D’Angelo, Lisa Romero, Shanna Cox, Lee Warner, Wanda Barfield
Journal: MMWR Morbidity and Mortality Weekly Report (2023)

Most pregnancy-related deaths due to mental health conditions, which include overdose and poisoning related to substance use disorder, occur during the late (43-365-day) postpartum period (1). Adverse childhood experiences and stressful life events are associated with increased substance use during pregnancy (2,3). Pregnancy Risk Assessment Monitoring System (PRAMS) respondents in seven states with high opioid overdose mortality rates were recontacted 9-10 months after giving birth in 2019 and asked about postpartum prescription opioid misuse,* tobacco use, unhealthy alcohol use,† and use of other substances.§ Substance and polysubstance use prevalence estimates were calculated, stratified by mental health and social adversity indicators. Overall, 25.6% of respondents reported postpartum substance use, and 5.9% reported polysubstance use. The following conditions were associated with higher substance and polysubstance use prevalence in postpartum women: depressive symptoms, depression, anxiety, adverse childhood experiences, and stressful life events. Substance use prevalence was higher among women who experienced six or more stressful life events during the year preceding the birth (67.1%) or four adverse childhood experiences related to household dysfunction (57.9%). One in five respondents who experienced six or more stressful life events in the year before giving birth and 26.3% of women with four adverse childhood experiences reported postpartum polysubstance use. Clinical and community- and systems-level interventions to improve postpartum health can include screening and treatment for depression, anxiety, and substance use disorders during the postpartum period. Evidence-based strategies can prevent adverse childhood experiences and mitigate the immediate and long-term harms.¶.
Error in the Byline
Journal: JAMA Network Open (2023)

Shawniqua Williams Roberson, MEng, MD; Samuel Nwosu, MS; Erin M. Collar, MPH; Amy L. Kiehl, MA; Fiona E. Harrison, PhD; Julie Bastarache, MD, PhD; Jo Ellen Wilson, MD, MPH; Matthew F. Mart, MD, MSCI; Jonathan E. Sevransky, MD, MHS; E. Wesley Ely, MD, MPH; Christopher J. Lindsell, PhD; James C. Jackson, PsyD; VICTAS Investigators; Katherine Nugent; Christine Spainhour; Carmen Polito; Brooks Moore; Lovie Negrin; Akram Khan; Bory Kea; Olivia Krol; Ebaad Haq; Vincent Pinkert; Kelly Nguyen; Samuel M Brown; Joseph Bledsoe; Ithan Peltan; Darrin Applegate; Brent Armbuster; Quinn Montgomery; Katie Brown; Austin Daw; Michelle Gong; Michael Aboodi; Jen-Ting (Tina) Chen; Aluko Hope; Swarna Gummadi; Brenda Lopez; Jeremiah Hinson; David Hager; Erin Ricketts; Johnathan Clare; Breana McBryde; Casey M. Clements; Ognjen Gajic; Rahul Kashyap; Derek Vanmeter; Laurence Busse; Mary McBride; Adit Ginde; Marc Moss; Lani Finck; Michelle Howell; Jeffrey McKeehan; Carrie Higgins; Aaron Barksdale; Dan Kalin; Derek Kruse; Katlyn Hilz; Nida Qadir; Steven Y. Chang; Rebecca Beutler; Andrea Tam; Estelle S. Harris; Scott T. Youngquist; Elizabeth A. Middleton; Ervin Davidov; Amber Plante; Justin Belsky; Jonathan Siner; Charles Wira; Carolyn Brokowski; Jay Steingrub; Howard Smithline; Sherell Thorton-Thompson; Alpha Fowler; Stephen Miller; Kyle Narron; Michael A. Pusckarich; Matthew E. Prekker; Audrey Hendrickson; James Quinn; Jennifer Wilson; Joseph Levitt; Rosen Mann; Anita Visweswaran; Nina Gentile; Nathaniel Marchetti; Hannah Reimer; Faheem Guirgis; Lisa Jones; Lauren Black; Morgan Henson; Nuala J. Meyer; John C. Greenwood; Caroline Ittner; Emanuel Rivers; Namita Jayaprakash; Jayna Gardner-Gray; Gina Hurst; Jacqueline Pflaum; Anja Kathrin Jaehne; Jasreen Gill; Aaron Cook; David R Janz; Derek Vonderhaar; Connie Romaine; R. Gentry Wilkerson; Michael T. McCurdy; Dana Beach; Kyra Lasko; Richard Gill; Katherine Price; Lisa Dickson; Abhijit Duggal; Sharon E. Mace; R. Duncan Hite; Andrei Hastings; Jason Haukoos; Ivor Dougla; Stacy Trent; Carolynn Lyle; Alicia Cupelo; Stephanie Gravitz; Terra Hiller; Judy Oakes; Frank LoVecchio; Pedro Quiroga; Shiloh Danley; Mary Mulrow; Amanda Encinas; Andrew Goodwin; Gregory Hall; Abigail Grady; Matthew Exline; Thomas Terndrup; Sonal Pannu; Emily Robart; Sarah Karow; D. Clark Files; Lane Smith; Kevin Gibbs; Lori Flores; Stephen M. Pastores; David J. Shaz; Natalie Kostelecky; Chad Chase; Elizabeth (Liz) Wilkins; David Gaieski; Michael Baram; Daniel Schwegler; Nicole Renzi; Jarrod M. Mosier; Cameron Hypes; Elizabeth Salvagio Campbell; Michael Hooper; Joshua Sill; Kate Mitchell; Kristin Hudock; Michael Lyons; Kari Gordner; Yousef Ahmad; Autumn Studer; Jacqueline Davis; Matthew Barrett; Jason Nomura; Jennifer Knox; Pauline Park; Ivan Co ; Jakob McSparron; Robert Hyzy; Kelli McDonough; Sinan Hanna; Wesley H. Self; Matthew W. Semler; Margaret Hays; Racquel Bartz; Alexander Limkakeng; Katherine Sweeney; Rachael Woodburn; Munish Goyal; Akram Zaaqoq; Theresa Moriarty; John Oropello; Ziya Zhang
Informing a Rational Approach to Antimicrobial Prophylaxis in Open Pancreatoduodenectomy
Authors: Anthony Charles, Preeti N. Malani
Journal: JAMA (2023)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal