tbuckley/cabot-search huggingface dataset:
The 2023 report of the Lancet Countdown on health and climate change: the imperative for a health-centred response in a world facing irreversible harms
Authors: Marina Romanello, Claudia di Napoli, Carole Green, Harry Kennard, Pete Lampard, Daniel Scamman, Maria Walawender, Zakari Ali, Nadia Ameli, Sonja Ayeb-Karlsson, Paul J Beggs, Kristine Belesova, Lea Berrang Ford, Kathryn Bowen, Wenjia Cai, Max Callaghan, Diarmid Campbell-Lendrum, Jonathan Chambers, Troy J Cross, Kim R van Daalen, Carole Dalin, Niheer Dasandi, Shouro Dasgupta, Michael Davies, Paula Dominguez-Salas, Robert Dubrow, Kristie L Ebi, Matthew Eckelman, Paul Ekins, Chris Freyberg, Olga Gasparyan, Georgiana Gordon-Strachan, Hilary Graham, Samuel H Gunther, Ian Hamilton, Yun Hang, Risto Hänninen, Stella Hartinger, Kehan He, Julian Heidecke, Jeremy J Hess, Shih-Che Hsu, Louis Jamart, Slava Jankin, Ollie Jay, Ilan Kelman, Gregor Kiesewetter, Patrick Kinney, Dominic Kniveton, Rostislav Kouznetsov, Francesca Larosa, Jason K W Lee, Bruno Lemke, Yang Liu, Zhao Liu, Melissa Lott, Martín Lotto Batista, Rachel Lowe, Maquins Odhiambo Sewe, Jaime Martinez-Urtaza, Mark Maslin, Lucy McAllister, Celia McMichael, Zhifu Mi, James Milner, Kelton Minor, Jan C Minx, Nahid Mohajeri, Natalie C Momen, Maziar Moradi-Lakeh, Karyn Morrissey, Simon Munzert, Kris A Murray, Tara Neville, Maria Nilsson, Nick Obradovich, Megan B O'Hare, Camile Oliveira, Tadj Oreszczyn, Matthias Otto, Fereidoon Owfi, Olivia Pearman, Frank Pega, Andrew Pershing, Mahnaz Rabbaniha, Jamie Rickman, Elizabeth J Z Robinson, Joacim Rocklöv, Renee N Salas, Jan C Semenza, Jodi D Sherman, Joy Shumake-Guillemot, Grant Silbert, Mikhail Sofiev, Marco Springmann, Jennifer D Stowell, Meisam Tabatabaei, Jonathon Taylor, Ross Thompson, Cathryn Tonne, Marina Treskova, Joaquin A Trinanes, Fabian Wagner, Laura Warnecke, Hannah Whitcombe, Matthew Winning, Arthur Wyns, Marisol Yglesias-González, Shihui Zhang, Ying Zhang, Qiao Zhu, Peng Gong, Hugh Montgomery, Anthony Costello
Journal: The Lancet (2023)
Deferred cord clamping, cord milking, and immediate cord clamping at preterm birth: a systematic review and individual participant data meta-analysis
Authors: Anna Lene Seidler, Mason Aberoumand, Kylie E Hunter, Angie Barba, Sol Libesman, Jonathan G Williams, Nipun Shrestha, Jannik Aagerup, James X Sotiropoulos, Alan A Montgomery, Gillian M L Gyte, Lelia Duley, Lisa M Askie, Anna Lene Seidler, Mason Aberoumand, Kylie E Hunter, Angie Barba, Sol Libesman, Jonathan G Williams, Nipun Shrestha, Jannik Aagerup, James X Sotiropoulos, Alan A Montgomery, Gillian M L Gyte, Aashim Garg, Aditi Kumar, Aidan C Tan, Amir Kugelman, Angela C Webster, Anu A George, Anu Thukral, Anup C Katheria, Arjan B te Pas, Ashish KC, Berndt Urlesberger, Bernhard Schwaberger, Carl H Backes, Catalina De Paco Matallana, Chamnan Tanprasertkul, Chayatat Ruangkit, Deepak Chawla, Douglas A Blank, Emel Okulu, Eugene M Dempsey, Govindu Ram Mohan, Graeme R Polglase, Guillermo Carroli, Heidi K Al-Wassia, Heike Rabe, Helen G Liley, Hytham Atia, Islam Nour, Jiang-Qin Liu, John Kattwinkel, Jon S Dorling, Judith S Mercer, Justin B Josephsen, Karen D Fairchild, Kedra Wallace, Kellie E Murphy, Kristy P Robledo, Manizheh M Gharehbaghi, Margarita de Veciana, Maria Goya, Martin Kluckow, Melissa I March, Michael P Meyer, Mukul K Mangla, Nahed E Allam, Nehad Nasef, Niraj K Dipak, Ola Andersson, Peter G Davis, Pharuhad Pongmee, Richard D Riley, Robert John Simes, Ronny Knol, Saadet Arsan, Shashank Shekhar, Sheila S Belk, Shigeharu Hosono, Shiraz Badurdeen, Simone Pratesi, Sofia Dias, Stuart B Hooper, Tanushree Sahoo, Thomas P A Debray, Varanattu C Manoj, Venkataseshan Sundaram, Victor Lago, Vikram Datta, Walid El-Naggar, Waldemar A Carlo, William O Tarnow-Mordi, Lelia Duley, Lisa M Askie
Journal: The Lancet (2023)
Short, medium, and long deferral of umbilical cord clamping compared with umbilical cord milking and immediate clamping at preterm birth: a systematic review and network meta-analysis with individual participant data
Authors: Anna Lene Seidler, Sol Libesman, Kylie E Hunter, Angie Barba, Mason Aberoumand, Jonathan G Williams, Nipun Shrestha, Jannik Aagerup, James X Sotiropoulos, Alan A Montgomery, Gillian M L Gyte, Lelia Duley, Lisa M Askie, Anna Lene Seidler, Sol Libesman, Kylie E Hunter, Angie Barba, Mason Aberoumand, Jonathan G Williams, Nipun Shrestha, Jannik Aagerup, James X Sotiropoulos, Alan A Montgomery, Gillian M L Gyte, William O Tarnow-Mordi, Walid El-Naggar, Waldemar A Carlo, Vikram Datta, Victor Lago, Venkataseshan Sundaram, Varanattu C Manoj, Thomas P A Debray, Tanushree Sahoo, Tanai Trongkamonthum, Stuart B Hooper, Sofia Dias, Simone Pratesi, Shiraz Badurdeen, Shigeharu Hosono, Sheila S Belk, Shashank Shekhar, Sangkae Chamnanvanakij, Saadet Arsan, Ronny Knol, Robert John Simes, Richard D Riley, Pharuhad Pongmee, Peter G Davis, Ola Andersson, Niraj K Dipak, Nehad Nasef, Nahed E Allam, Mukul K Mangla, Michael P Meyer, Melissa I March, Martin Kluckow, Maria Goya, Margarita de Veciana, Manizheh M Gharehbaghi, Kristy P Robledo, Kellie E Murphy, Kedra Wallace, Karen D Fairchild, Justin B Josephsen, Judith S Mercer, Jon S Dorling, John Kattwinkel, Jiang-Qin Liu, Islam Nour, Hytham Atia, Helen G Liley, Heike Rabe, Heidi K Al-Wassia, Guillermo Carroli, Graeme R Polglase, Govindu Ram Mohan, Eugene M Dempsey, Emel Okulu, Douglas A Blank, Deepak Chawla, Chayatat Ruangkit, Chamnan Tanprasertkul, Catalina De Paco Matallana, Carl H Backes, Bernhard Schwaberger, Berndt Urlesberger, Ashish KC, Arjan B te Pas, Anup C Katheria, Anu Thukral, Anu A George, Angela C Webster, Amir Kugelman, Aidan C Tan, Aditi Kumar, Aashim Garg, Lelia Duley, Lisa M Askie
Journal: The Lancet (2023)
Corrigendum to “Head-to-head Comparison of the Diagnostic Accuracy of Prostate-specific Membrane Antigen Positron Emission Tomography and Conventional Imaging Modalities for Initial Staging of Intermediate- to High-risk Prostate Cancer: A Systematic Review and Meta-analysis” [Eur. Urol. 84(1) (2023) 36–48]
Authors: Kit Mun Chow, Wei Zheng So, Han Jie Lee, Alvin Lee, Dominic Wei Ting Yap, Yemisi Takwoingi, Kae Jack Tay, Jeffrey Tuan, Sue Ping Thang, Winnie Lam, John Yuen, Nathan Lawrentschuk, Michael S. Hofman, Declan G. Murphy, Kenneth Chen
Journal: European Urology (2023)
MO1-3 Real-world data of first-line treatment with pembrolizumab for NSCLC with high PD-L1 expression (HOT/NJLCG2001 secondary report)
Authors: Kazunari Tateishi, Hidenori Mizugaki, Yasuyuki Ikezawa, Ryo Morita, Keiki Yokoo, Toshiyuki Sumi, Hajime Kikuchi, Yasuo Kitamura, Atsushi Nakamura, Maki Kobayashi, Mari Aso, Nozomu Kimura, Fumiaki Yoshiike, Megumi Furuta, Hisashi Tanaka, Motoki Sekikawa, Tsutomu Hashiya, Yuka Fujita, Satoshi Oizumi
Journal: Annals of Oncology (2023)
PS3-3 Pembrolizumab + chemoradiation therapy for locally advanced head and neck squamous cell carcinoma (HNSCC): KEYNOTE-412
Authors: Makoto Tahara, Jean-Pascal Machiels, Yungan Tao, Barbara Burtness, Danny Rischin, Gustavo V. Alves, Iane Pinto Figueiredo Lima, Brett G.M. Hughes, Yoann Pointreau, Sercan Aksoy, Simon Laban, Richard Greil, Martin Burian, Marcin Hetnal, Lisa Licitra, Ramona Swaby, Yayan Zhang, Behzad Bidadi, Lillian L. Siu
Journal: Annals of Oncology (2023)
PS3-2 Brexucabtagene autoleucel in relapsed/refractory mantle cell lymphoma (R/R MCL) in ZUMA-2: Durable responder analysis
Authors: Javier Munoz, Patrick M. Reagan, Andre Goy, David B. Miklos, Dan Zheng, Xiang Fang, Rhine R. Shen, Rubina Siddiqi, Ioana Kloos, Marie José Kersten, Michael Wang
Journal: Annals of Oncology (2023)
Contrasting Health Outcomes following a Severe Smoke Episode and Ambient Air Pollution in Early Life: Findings from an Australian Data Linkage Cohort Study of Hospital Utilization
Authors: Myriam Ziou, Caroline X. Gao, Amanda J. Wheeler, Graeme R. Zosky, Nicola Stephens, Luke D. Knibbs, Shannon M. Melody, Alison J. Venn, Marita F. Dalton, Shyamali C. Dharmage, Fay H. Johnston
Journal: Environmental Health Perspectives (2023)

Episodic spikes in air pollution due to landscape fires are increasing, and their potential for longer term health impacts is uncertain.Our objective is to evaluate associations between exposure in utero and in infancy to severe pollution from a mine fire, background ambient air pollution, and subsequent hospital care.We linked health records of births, emergency department (ED) visits, and hospitalizations of children born in the Latrobe Valley, Australia, 2012-2015, which included a severe pollution episode from a mine fire (9 February 2014 to 25 March 2014). We assigned modeled exposure estimates for fire-related and ambient particulate matter with an aerodynamic diameter of 2.5μm (PM2.5) to residential address. We used logistic regression to estimate associations with hospital visits for any cause and groupings of infectious, allergic, and respiratory conditions. Outcomes were assessed for the first year of life in the in utero cohort and the year following the fire in the infant cohort. We estimated exposure-response for both fire-related and ambient PM2.5 and also employed inverse probability weighting using the propensity score to compare exposed and not/minimally exposed children.Prenatal exposure to fire-related PM2.5 was associated with ED presentations for allergies/skin rash [odds ratio (OR)=1.34, 95% confidence interval (CI): 1.01, 1.76 per 240 μg/m3 increase]. Exposure in utero to ambient PM2.5 was associated with overall presentations (OR=1.18, 95% CI: 1.05, 1.33 per 1.4 μg/m3) and visits for infections (ED: OR=1.13, 95% CI: 0.98, 1.29; hospitalizations: OR=1.23, 95% CI: 1.00, 1.52). Exposure in infancy to fire-related PM2.5 compared to no/minimal exposure, was associated with ED presentations for respiratory (OR=1.37, 95% CI: 1.05, 1.80) and infectious conditions (any: OR=1.21, 95% CI: 0.98, 1.49; respiratory-related: OR=1.39, 95% CI: 1.05, 1.83). Early life exposure to ambient PM2.5 was associated with overall ED visits (OR=1.17, 95% CI: 1.05, 1.30 per 1.4 μg/m3 increase).Higher episodic and lower ambient concentrations of PM2.5 in early life were associated with visits for allergic, respiratory, and infectious conditions. Our findings also indicated differences in associations at the two developmental stages. https://doi.org/10.1289/EHP12238.
O17-2 A phase II trial of tazemetostat for patients with unresectable or metastatic epithelioid sarcoma (TAZETTA trial)
Authors: Shosuke Kita, Tatsunori Shimoi, Keigo Komine, Masashi Ando, Hiroshi Ariyama, Natsuko Okita, Ryo Sadachi, Naoko So, Satoshi Azuma, Yuki Kazumi, Kan Yonemori
Journal: Annals of Oncology (2023)
O16-5 Nivolumab for cancer of unknown primary (CUP): Initial results from an expanded access program (NivoCUP2, WJOG14620M)
Authors: Junko Tanizaki, Kan Yonemori, Yuichi Takiguchi, Kohei Akiyoshi, Keigo Komine, Yusuke Onozawa, Mariko Sato, Kenro Hirata, Takuma Onoe, Ryotaro Ohkuma, Yosuke Horita, Hironobu Minami, Kazunori Honda, Koichi Suyama, Akihiko Ito, Yasutaka Chiba, Kazuto Nishio, Hidetoshi Hayashi
Journal: Annals of Oncology (2023)
O2-5 Quality of sex in cervical cancer survivors post-treatment: A systematic review
Authors: Patricia Angel, Felix Wijovi, Rivaldo Steven Heriyanto, Natasya Reina, Gisela Meydilin Sanjaya, Angeline Tancherla, Fernando Dharmaraja, Alexy Oktoman Djohansjah, Darien Alfa Cipta
Journal: Annals of Oncology (2023)
Silencing of genes by promoter hypermethylation shapes tumor microenvironment and resistance to immunotherapy in clear-cell renal cell carcinomas
Authors: Xiaofan Lu, Yann-Alexandre Vano, Xiaoping Su, Alexandra Helleux, Véronique Lindner, Roger Mouawad, Jean-Philippe Spano, Morgan Rouprêt, Eva Compérat, Virginie Verkarre, Cheng-Ming Sun, Mostefa Bennamoun, Hervé Lang, Philippe Barthelemy, Wenxuan Cheng, Li Xu, Irwin Davidson, Fangrong Yan, Wolf Hervé Fridman, Catherine Sautes-Fridman, Stéphane Oudard, Gabriel G. Malouf
Journal: Cell Reports Medicine (2023)

The efficacy of immune checkpoint inhibitors varies in clear-cell renal cell carcinoma (ccRCC), with notable primary resistance among patients. Here, we integrate epigenetic (DNA methylation) and transcriptome data to identify a ccRCC subtype characterized by cancer-specific promoter hypermethylation and epigenetic silencing of Polycomb targets. We develop and validate an index of methylation-based epigenetic silencing (iMES) that predicts primary resistance to immune checkpoint inhibition (ICI) in the BIONIKK trial. High iMES is associated with VEGF pathway silencing, endothelial cell depletion, immune activation/suppression, EZH2 activation, BAP1/SETD2 deficiency, and resistance to ICI. Combination therapy with hypomethylating agents or tyrosine kinase inhibitors may benefit patients with high iMES. Intriguingly, tumors with low iMES exhibit increased endothelial cells and improved ICI response, suggesting the importance of angiogenesis in ICI treatment. We also develop a transcriptome-based analogous system for extended applicability of iMES. Our study underscores the interplay between epigenetic alterations and tumor microenvironment in determining immunotherapy response.
Quantifying Enteropathogen Contamination along Chicken Value Chains in Maputo, Mozambique: A Multidisciplinary and Mixed-Methods Approach to Identifying High Exposure Settings
Authors: Frederica Lamar, Hermógenes N. Mucache, Amelia Mondlane-Milisse, Kelsey J. Jesser, Courtney Victor, José M. Fafetine, Joaquim Ângelo Osvaldo Saíde, Eric M. Fèvre, Bethany A. Caruso, Matthew C. Freeman, Karen Levy
Journal: Environmental Health Perspectives (2023)

Small-scale poultry production is widespread and increasing in low- and middle-income countries (LMICs). Exposure to enteropathogens in poultry feces increases the hazard of human infection and related sequela, and the burden of disease due to enteric infection in children <5 y in particular is substantial. Yet, the containment and management of poultry-associated fecal waste in informal settings in LMICs is largely unregulated.
O16-2 Phase I trial of NY-ESO-1 TCR-T cell therapy combined with nanoparticulate vaccine but without lymphodepletion for STS
Authors: Mikiya Ishihara, Yoshihiro Nishida, Shigehisa Kitano, Akira Kawai, Naozumi Harada, Yoshihiro Miyahara, Hiroyoshi Hattori, Kohichi Takada, Makoto Emori, Shigeki Kakunaga, Makoto Endo, Yoshihiro Matsumoto, Tetsuro Sasada, Eiichi Sato, Tomomi Yamada, Akihiko Matsumine, Yasuhiro Nagata, Shinichi Kageyama, Hiroshi Shiku
Journal: Annals of Oncology (2023)
Examining Exposure Differences between Residential and Smartphone Mobility-Based Greenness in a Cohort of the Nurses’ Health Study
Authors: Grete E. Wilt, Charlotte Roscoe, Cindy R. Hu, Hari S. Iyer, Unnati V. Mehta, Brent A. Coull, Jaime E. Hart, Steven Gortmaker, Francine Laden, Peter James
Journal: Environmental Health Perspectives (2023)
MO2-2 Post-marketing observational safety study of durvalumab in Japanese patients with unresectable stage III NSCLC (PACIFIC regimen)
Authors: Terufumi Kato, Masahiro Endo, Yoshinobu Saito, Tomohisa Baba, Kayoko Tsujino, Keiko Shibuya, Yutaka Fujiwara, Hirotsugu Kenmotsu, Katsunori Oikado, Kei Sakamoto, Masahiro Nii, Mariko Hotta, Yuka Noda, Toshimitsu Tokimoto, Fumikazu Sakai, Masahiko Kusumoto
Journal: Annals of Oncology (2023)
O15-4 Outcomes of genetic aberrations and clinical features in cholangiocarcinoma: Report from the MASTER KEY Project
Authors: Yuta Maruki, Chigusa Morizane, Manabu Muto, Ichiro Kinoshita, Eishi Baba, Masanobu Takahashi, Ryo Sadachi, Hitomi Okuma Sumiyoshi, Kan Yonemori, Takushi Okusaka
Journal: Annals of Oncology (2023)
O1-1 A comparative study of TMB values in comprehensive genomic profiling assays in different gene panels
Authors: Takahiro Nishino, Kuniko Sunami, Takashi Kubo, Mio Yumura, Tomoyo Yasuda, Mayuko Kitami, Momoko Nagai, Eisaku Furukawa, Mamoru Kato, Hitoshi Ichikawa, Yushi Yatabe, Takashi Kohno
Journal: Annals of Oncology (2023)
SY03-2 Molecular imaging unveils realistic features of T cell activation signaling via TCRs, costimulatory and coinhibitory receptors and CARs
Authors: Tadashi Yokosuka, Wataru Nishi, Ei Wakamatsu, Hitoshi Nishijima, Arata Takeuchi, Ryohei Matsushima, Tetsushi Nishikawa, Yosuke Yoshida, Mamokin Maksim, Malcolm Brenner, Hiroaki Machiyama
Journal: Annals of Oncology (2023)
O1-2 Prospective study of comprehensive genomic profiling for chemotherapy-naive cancer patients (FIRST-Dx study)
Authors: Hiromichi Ebi, Junichi Matsubara, Kumi Mukai, Tomohiro Kondo, Masahiro Yoshioka, Hidenori Kage, Katsutoshi Oda, Ryo Kudo, Sadakatsu Ikeda, Ryuji Hayashi, Naomi Tokudome, Nobuyuki Yamamoto, Kei Muro, Manabu Muto
Journal: Annals of Oncology (2023)
O4-5 Circulating tumor DNA dynamics as an early predictor of recurrence in patients with radically resected colorectal cancer: GALAXY study in the CIRCULATE-Japan
Authors: Saori Mishima, Daisuke Kotani, Yoshiaki Nakamura, Hideaki Bando, Masaaki Miyo, Atsushi Hamabe, Jun Watanabe, Keiji Hirata, Naoya Akazawa, Kozo Kataoka, Kun-Huei Yeh, George Laliotis, Adham Jurdi, Minetta Liu, Hiroya Taniguchi, Ichiro Takemasa, Takeshi Kato, Takayuki Yoshino, Eiji Oki
Journal: Annals of Oncology (2023)
O3-1 Financial toxicity and cost-related experience in molecular and immune therapies: A multicenter questionnaire survey
Authors: Sena Yamamoto, Chiharu Kondoh, Hideko Nakagoshi, Mayuko Kakumen, Kana Yasuhara, Mayumi Nakai, Naoko Kodani, Kazumi Sunda, Chizuru Higashide, Megumi Katayama, Harue Arao
Journal: Annals of Oncology (2023)
Prenatal Exposure to PFAS, Associations with Preterm Birth and Modification by Maternal Estrogen Levels: The Maoming Birth Study
Authors: Xiao-Di Qin, Yang Zhou, Michael S. Bloom, Zhengmin (Min) Qian, Sarah Dee Geiger, Michael G. Vaughn, Chu Chu, Qing-Qing Li, Bo-Yi Yang, Li-Wen Hu, Yunjiang Yu, Xiao-Wen Zeng, Guang-Hui Dong
Journal: Environmental Health Perspectives (2023)

Estrogens play a critical role in parturition, and poly- and perfluoroalkyl substances (PFAS), which have estrogenic effects, have been associated with preterm birth. However, the impact of estrogens on the association between PFAS and preterm birth is unknown.The objective of this study is to investigate if estrogens modified the association between PFAS and preterm birth, using a nested case-control study design.A total of 371 preterm births and 508 controls were selected from a birth cohort study in China between 2016 and 2018. Perfluorobutanoic acid (PFBA), perfluorohexanesulfonic acid (PFHxS) and its branched isomer, perfluorooctanoic acid (PFOA), perfluorooctanesulfonic acid (PFOS) and its branched isomer, and perfluorononanoic acid (PFNA) were quantified in maternal serum (mean gestational age of 32 wk). Estradiol and estriol were quantified in cord serum. Preterm birth was defined as live delivery at <37 gestational weeks. Causal mediation analysis was used to estimate the mediation and interaction effects of estrogen on the association between PFAS and preterm birth. Latent profile analysis was used to identify important estrogen profiles. Multiple linear regression was used to estimate associations between PFAS and preterm birth and interactions between PFAS and estrogens on preterm birth.Overall, higher odds ratios (ORs) of preterm birth were associated with each 1 ln-unit PFAS increase: PFBA [1.20, 95% confidence interval (CI): 1.14, 1.26], PFNA (1.30, 95% CI: 1.21, 1.39), PFOA (1.98, 95% CI: 1.54, 2.55), and PFOS (1.91, 95% CI: 1.76, 2.07) and its branched isomer (1.91, 95% CI: 1.90, 1.92). We detected statistically significant interactions between cord estradiol and PFAS on preterm birth, while no mediation effects of cord estrogen were observed. The ORs of PFOS (4.29, 95% CI: 1.31, 8.25), its branched isomer (6.71, 95% CI: 1.06, 11.91), and preterm birth were greater for participants with high cord estrogen levels than for participants with low cord estrogen levels.Our findings suggest that estrogen modified the association between maternal PFAS exposure and preterm birth. Further studies on maternal PFAS exposure and preterm birth, taking interaction effects of cord estrogens into account, are warranted. https://doi.org/10.1289/EHP11377.
O4-3 An update analysis of the JACCRO CC-16: Ramucirumab plus FOLFIRI for RAS wild-type mCRC refractory to anti-EGFR antibody
Authors: Dai Manaka, Akihito Tsuji, Masatsune Shibutani, Keiichiro Ishibashi, Taichi Yabuno, Shu Okamura, Takumi Furuya, Chihiro Tanaka, Masato Nakamura, Tamotsu Sagawa, Takanori Watanabe, Manabu Shiozawa, Yu Sunakawa, Hirofumi Ota, Masahito Kotaka, Hiroyuki Okuyama, Yoshihiro Okita, Japan Clinical Cancer Research Organization, Wataru Ichikawa, Masashi Fujii
Journal: Annals of Oncology (2023)
PS4-4 Early tumor shrinkage and depth of response with first-line panitumumab or bevacizumab and mFOLFOX treatment in PARADIGM
Authors: Kei Muro, Jun Watanabe, Kohei Shitara, Kentaro Yamazaki, Hisatsugu Ohori, Manabu Shiozawa, Hirofumi Yasui, Eiji Oki, Takeo Sato, Takeshi Naito, Yoshito Komatsu, Takeshi Kato, Masamitsu Hihara, Junpei Soeda, Kouji Yamamoto, Kiwamu Akagi, Atsushi Ochiai, Katsuya Tsuchihara, Takayuki Yoshino
Journal: Annals of Oncology (2023)
MO1-6 Steroid-resistant and refractory irAEs requiring additional immunosuppressants to steroids in advanced NSCLC patients
Authors: Yukiko Shimoda, Tatsuya Yoshida, Masahiro Torasawa, Akiko Tateishi, Yuji Matsumoto, Yuki Shinno, Yusuke Okuma, Yasushi Goto, Hidehito Horinouchi, Noboru Yamamoto, Yuichiro Ohe
Journal: Annals of Oncology (2023)
Fiber-deficient diet inhibits colitis through the regulation of the niche and metabolism of a gut pathobiont
Authors: Peter Kuffa, Joseph M. Pickard, Austin Campbell, Misa Yamashita, Sadie R. Schaus, Eric C. Martens, Thomas M. Schmidt, Naohiro Inohara, Gabriel Núñez, Roberta Caruso
Journal: Cell Host & Microbe (2023)
O13-5 Rejuvenated BCMA-specific CD8αβ+ memory T cells to treat multiple myeloma using induced pluripotent stem cell technology
Authors: Jooeun Bae, Shuichi Kitayama, Zach Herbert, Laurence Daheron, Keiji Kurata, Nikhil Munshi, Shin Kaneko, Kenneth Anderson
Journal: Annals of Oncology (2023)
PS3-5 Futibatinib for intrahepatic cholangiocarcinoma with FGFR2 fusions/rearrangements: Japanese sub-analysis of FOENIX-CCA2
Authors: Chigusa Morizane, Yoshito Komatsu, Kunihiro Masuda, Masashi Kanai, Tatsuya Ioka, Makoto Ueno, Masato Ozaka, Takashi Mizuno, Daisuke Sakai, Masafumi Nakamura, Masashi Shimura, Goyal Lipika, Junji Furuse
Journal: Annals of Oncology (2023)
PS4-2 PD-1 blockade as curative intent therapy in mismatch repair deficient locally advanced rectal cancer
Authors: Andrea Cercek, Melissa Lumish, Jenna Sinopoli, Jill Weiss, Jinru Shia, Zsofia Stadler, Rona Yaeger, J. Joshua Smith, Leonard Saltz, Maria Widmar, Christopher Crane, Paul Romesser, Emmanouil P. Pappou, Philip Paty, Julio Garcia-Aguilar, Mithat Gonen, Martin Weiser
Journal: Annals of Oncology (2023)
PS1-2 First report of cohort 3 and mature survival data from the U31402-A-U102 study of HER3-DXd in EGFR-mutated NSCLC
Authors: Hidetoshi Hayashi, Helena A. Yu, Christina Baik, Dong-Wan Kim, Melissa L. Johnson, Makoto Nishio, James Chih-Hsin Yang, Wu-Chou Su, Kathryn A. Gold, Marianna Koczywas, Egbert F. Smit, Conor Steuer, Enriqueta Felip, Haruyasu Murakami, Sang-We Kim, Ben Kim, Xin Su, Yoshimi Tanaka, Pang-Dian Fan, Frederique Cantero
Journal: Annals of Oncology (2023)
MO2-5 Early mortality factors in immune checkpoint inhibitor monotherapy for advanced or metastatic non-small cell lung cancer
Authors: Eiji Takeuchi, Kensuke Kondo, Yoshio Okano, Seiya Ichihara, Michihiro Kunishige, Naoki Kadota, Hisanori Machida, Nobuo Hatakeyama, Keishi Naruse, Hirokazu Ogino, Hiroshi Nokihara, Tsutomu Shinohara, Yasuhiko Nishioka
Journal: Annals of Oncology (2023)
MO6-5 Tumor microenvironment and clinical efficacy of atezolizumab plus bevacizumab for hepatocellular carcinoma
Authors: Tomonao Taira, Motohiro Kojima, Shota Yamaguchi, Kanae Inoue, Hiroki Eguchi, Kei Okumura, Taro Shibuki, Tomoyuki Satake, Kazuo Watanabe, Mitsuhito Sasaki, Hiroshi Imaoka, Shuichi Mitsunaga, Genichiro Ishii, Masafumi Ikeda
Journal: Annals of Oncology (2023)
MO7-5 Clinical and genomic features of MSI-H and TMB-high pancreatic cancer: A real world data from the C-CAT database
Authors: Tomoki Sakakida, Takeshi Ishikawa, Toshifumi Doi, Ryuichi Morita, Masahiro Iwasaku, Koichi Takayama, Yoshito Itoh
Journal: Annals of Oncology (2023)