tbuckley/cabot-search huggingface dataset:
Rates of avoidable hospitalization by insurance status in Massachusetts and Maryland
Authors: J. S. Weissman
Journal: JAMA (1992)

<h3>Objective.</h3> —To determine whether uninsured and Medicaid patients have higher rates of avoidable hospitalizations than do insured patients. <h3>Design.</h3> —We used 1987 computerized hospital discharge data to select a cross-sectional sample of hospitalized patients. Population estimates from the<i>Current Population Survey</i>were used to estimate rates of admission, standardized for age and sex. <h3>Setting.</h3> —Nonfederal acute care hospitals in Massachusetts and Maryland. Patients.—All patients under 65 years of age who were uninsured, privately insured, or insured by Medicaid. Hospitalizations for obstetric and psychiatric conditions were excluded. <h3>Main Outcome Measures.</h3> —Relative risk of admission for 12 avoidable hospital conditions (AHCs) identified by a physician panel. <h3>Results.</h3> —Uninsured and Medicaid patients were more likely than insured patients to be hospitalized for AHCs. Rates for uninsured patients were significantly greater than for privately insured patients in Massachusetts for 10 of 12 individual AHCs, and in Maryland for five of 12 AHCs. After adjustment for baseline utilization, the results were statistically significant for 10 of 12 AHCs in Massachusetts and seven of 12 AHCs in Maryland. For Medicaid patients, rates were significantly greater than for privately insured patients for all AHCs in each state before adjustment, and for nine of 12 and seven of 12 AHCs in each state, respectively, after adjustment for baseline utilization. <h3>Conclusion.</h3> —Our findings suggest that patients who are uninsured or who have Medicaid coverage have higher rates of hospitalization for conditions that can often be treated out of hospital or avoided altogether. Our approach is potentially useful for routine monitoring of access and quality of care for selected groups of patients. (<i>JAMA</i>. 1992;268:2388-2394)
Respiratory rate as an indicator of acute respiratory dysfunction
Authors: T. R. Gravelyn
Journal: JAMA (1980)

To assess respiratory rate as an indicator of acute respiratory dysfunction, we studied 58 consecutive patients four times daily during the postoperative period. Of 825 measurements of respiratory rate, 726 (89%) were normal (24/min or less). Elevations in respiratory rate without respiratory dysfunction were found in only 4% of all measurements. Patients without lung disease had a mean respiratory rate of 18±4/min, while patients with an abnormal respiratory rate and respiratory dysfunction had a mean of 27±5/min. Our study demonstrates that respiratory rate, if carefully measured, is a sensitive and reasonably specific marker of acute respiratory dysfunction. (<i>JAMA</i>244:1123-1125, 1980)
Naloxone for diagnosis in methadone programs
Authors: P. H. Blachly
Journal: JAMA (1973)

Naloxone hydrochloride is safe, effective, rapid, and inexpensive for the diagnosis of physical dependence on opiates. It may be used in an outpatient setting with a minimum of personnel. Unlike urinalysis, it will distinguish a person who is physically dependent from one who is an occasional user, and in 10 to 35 minutes. A significant hazard exists in creating addicts to methadone hydrochloride, since a third of those applying to a methadone clinic without prior documentation of withdrawal in an institution showed no evidence of physical dependence.
The Spleen and Hypersplenism
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A wilderness of data.
Journal: BMJ (1977)

brief periods of enthusiasm, but unpredictable relief of pain or a higher mortality rate has not encouraged their widespread use.In the frail and elderly patient with other illnesses the lesser procedure of ganglion or root destruction (by alcohol, electrical, or thermocoagulation) is the treatment of choice.But pro- longed follow-up'0 shows that 8000 of patients have a recur- rence, and thus they may need subsequent treatment.For the younger patient in his 50s or 60s who needs some form of surgical procedure, fractional rhizotomy in expert hands is the preferred method of treatment.'4The recent introduction of the operating microscope for this purpose may well lessen its surgical morbidity and perhaps offset the effects of diminishing surgical experience which has often resulted from successful medical treatment.
Quality of physicians' office-care performance. Different for elderly than for younger adults?
Authors: T. F. Lyons
Journal: JAMA (1974)

Office records of 904 patient visits during six weeks in 1970 were examined for conformance to predetermined optimal standards of physician performance in seven categories of diagnoses or conditions. No overall evidence was found that primary-care physicians performed differently for the elderly than for younger adult patients in the office setting. (<i>JAMA</i>229:1621-1622, 1974)
Guidelines on the management of tuberculosis and HIV infection in the United Kingdom. Subcommittee of the Joint Tuberculosis Committee of the British Thoracic Society.
Journal: BMJ (1992)

Increases in the incidence of tuberculosis attributed to the HIV epidemic have been reported from the United States and several countries in Africa.1-3 These increases have occurred particularly in groups who are at high risk of both infections.There is evidence from the United States that the disease is often due to reactivation of latent infection, and it has been estimated that up to 30% ofpeople with previous tuberculous infection may develop clinical tuberculosis if they become infected with HIV.4A slight increase in the number of notifications of tuberculosis in England and Wales has recently been observed, but there is no evidence that this is related to HIV.s Tuberculosis often develops before other HIV related disease and is more often extrapulmonary than in the HIV negative patients, commonly affecting lymph nodes or being disseminated.Pulmonary lesions may be less often cavitated, but
Managing the care of the difficult patient in the emergency unit
Authors: H. J. Makadon
Journal: JAMA (1984)

An approach to managing the care of "difficult" patients in emergency units is presented in both theoretical and practical terms. Understanding the conflicts these patients create and how these are exacerbated in an emergency unit setting can often lead to straightforward plans for management. These plans should emphasize consistency as a way of both setting limits and reassuring patients and should set reasonable expectations for health care providers working with these patients. Clinical examples are given to illustrate the use of these principles. (<i>JAMA</i>1984;252:2585-2588)
Council on Medical Education American Medical Association 535 N Dearborn St, Chicago, IL 60610
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The cost of continuing medical education for family physicians
Authors: M. E. Faithe
Journal: JAMA (1979)

THE QUESTION often raised is how much does it cost practicing physicians to attend various continuing medical education endeavors? Family practitioners participating in a twoweek review course at the University of Nebraska College of Medicine provided information regarding their years in practice, size of community, and type of practice in order to determine the direct and indirect costs of one kind of continuing medical education. Results indicate that this type of review course incurs considerable cost to the family physician, but may present a small investment in terms of improved patient care. Twenty-four states have passed legislation requiring participation in continuing medical education as a condition for reregistration of the license to practice medicine, and more states are drafting such legislation.<sup>1</sup>Among the questions raised herein are those relating to cost of continuing medical education, weighted against the potential value of the educational programs to practitioners and their patients.
Clinique médicale des enfants: Affections de l'appareil respiratoire.
Journal: JAMA (1931)

Clinique médicale des enfants: Affections de l'appareil respiratoire. Deuxiéme série. Par P. Nobécourt, professeur de clinique médicale des enfants à la Faculté de médecine de Paris. Second edition. Paper. Price, 60 francs. Pp. 479, with 227 illustrations. Paris: Masson &amp; Cie, 1930. Nobécourt presents a series of practical clinics in two volumes. The material is presented as a series of case reports, many of which have been previously published in French journals. They are collected into these volumes and are made the subject of interesting comments and discussions by the author. The practical subjects that are considered are of general interest. The respiratory complications of measles, whooping cough, scarlet fever and typhoid receive detailed consideration. In addition, such subjects as pleurisy, bronchopneumonia, tuberculosis and asthma are discussed at considerable length and are illustrated with appropriate clinical records and roentgenograms. Pulmonary tuberculosis in infancy and childhood is discussed at some length
Leads from the MMWR. Urine testing for detection of marijuana: an advisory
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE SANITARY INQUIRY AS TO TENEMENT-HOUSES IN NEW YORK CITY.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Table of Contents
Authors: Nino Joy, Maia Mikeladze, Lisa Younk, Donna Tate, Stephen Davis, Maria Pereira, Stanko Skrtic, Petros Katsogiannos, Niclas Abrahamsson, Cherno Sidibeh, Santosh Dahgam, Marianne Månsson, Ulf Risérus, Joel Kullberg, Jan Eriksson, Benjamin Jensen, Thomas Nielsen, Andreas Fritzen, Jacob Holm, Annette Serup, Kamil Borkowski, Steve Risis, Simone Paerregaard, Ida Søgaard, Audrey Poupeau, Michelle Poulsen, Tao Ma, Christian Sina, Bente Kiens, Lise Madsen, Karsten Kristiansen, Jonas Treebak, Xiaowen Liu, Nikolaos Perakakis, Huizhi Gong, John Chamberland, Mary Brinkoetter, Ole-Petter Hamnvik, Christos Mantzoros, Jesper Hansen, Christian Krintel, Malin Hernebring, Tatu Haataja, Sofia De Marè, Sebastian Wasserstrom, Urszula Kosinska-Eriksson, Madelene Palmgren, Cecilia Holm, Karin Stenkula, Helena Jones, Karin Lindkvist-Petersson, Heekyung Chung, Winjet Chou, Dorothy Sears, Ruth Patterson, Nicholas Webster, Lesley Ellies, Wan-Ni Zhao, Shi-Qing Xu, Jian-Feng Liang, Liang Peng, Hong-Lin Liu, Zai Wang, Qing Fang, Meng Wang, Wei-Qin Yin, Wen-Jian Zhang, Jin-Ning Lou
Journal: Metabolism (2016)
COPENHAGEN
Journal: JAMA (1946)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Association News
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 1068: How humanized mouse models could be useful for immuno-oncology research
Authors: Jean-Francois Mirjolet, Josselin Caradec, Oliver Duchamp, Francis Bichat, Damien France, Caroline Mignard, Fabrice Viviani
Journal: Cancer Research (2019)

Abstract Immunotherapy is one of the most exiting recent breakthroughs in the field of cancer treatment. Different approaches are developed such as cancer vaccines, adoptive cellular immunotherapy or immune checkpoint blockade, and a number have been regulatory approved or are currently investigated in clinic. Effective immunity against cancer involves complex interaction between the tumor, the host and the environment. The assessment of cancer immunotherapy approaches in preclinical settings requires the use of appropriate animal models that sufficiently reflect the physiological situation in humans and that must be chosen carefully to address specific mechanisms of action. In light of evaluating the therapeutic potential of different immunomodulatory agents in mice xenografted with cancer cell lines or patient-derived xenografts, we developed multiple humanization strategies on different immuno-deficient mouse strains. Either human PBMCs, Hematopoietic Stem Cells (HSCs), or specific human immune cells such as Dendritic Cells (DCs), T cells, subset of T cells (e.g. gamma9 delta2 T cells) and NK cells were used, but also the combinations of immune subpopulations such as the co-transfer of autologous T cells and DCs. We will highlight some results of our therapeutic efficacy investigation and evaluation of novel immuno-oncology therapies eg. adoptive cell therapy, bispecific T-cell engager antibody, and vaccine immunomodulatory agents in such humanized mouse models, assessing survival, tumor growth and effects on tumors and immune cells by flow cytometry and immunohistochemistry analyses. All these different humanized models can permit to evidence significant antitumor efficacy of immunomodulatory agents in vivo and might help improve the success rate in clinical trials. Citation Format: Jean-Francois Mirjolet, Josselin Caradec, Oliver Duchamp, Francis Bichat, Damien France, Caroline Mignard, Fabrice Viviani. How humanized mouse models could be useful for immuno-oncology research [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1068.
Implementation of the quality training program in Spain.
Authors: Rafael Lopez, Antonio Anton, Enrique Aranda, Alfredo Carrato, Manuel Constenla, Juan Jesús Cruz, Eduardo Diaz-Rubio, Margarita Feyjoo, Jesus Garcia-Foncillas, Pedro Gascon, Vicente Guillem, Ilse Lugo, Carlos Camps
Journal: Journal of Clinical Oncology (2019)

11 Background: The ECO Foundation is a collaboration of experts representing the major Spanish hospitals in the pursuit of excellence in cancer treatment. Since 2015, ECO has been collaborating with ASCO (American Society of Clinical Oncology) in quality initiatives in cancer care, like the QOPI (Quality Oncology Practice Initiative) program and the QOPI Certification Program (QCP). The Quality Training Program (QTP) is a 6-month course with 3 in-person learning sessions that prepares oncology teams to design, implement and lead successful quality improvement activities in their practices. In 2018, ECO reached a new agreement with ASCO to implement this program in Spain. Methods: The QTP was developed in Spain by ECO in collaboration with ASCO, following the same methodology and contents of ASCO’s program. The first session was carried out in October 2018, with 12 Spanish teams participating with diverse quality improvement projects. The program counted with ASCO and ECO faculty, constituted by experts in the quality and oncology field. Results: Each QTP Spanish team counted with 2-3 representatives from their hospitals and developed an improvement project, following the methodology of the course, including a problem statement, process map, cause and effect diagram, diagnostic data, aim statement, measures, baseline data, priority/pay-off matrix of possible changes/interventions, change data, next steps/plan for sustainability, among others. The projects were mainly focused on the waiting time reduction in the Emergency Area and from the patient’s visit to the oncologist until treatment administration, burnout reduction on oncology professionals, improvement of the identification and management of complications for cancer patients receiving immunotherapy, improvement of the uniformity in the medical records registry, among others. QTP participants presented their projects’ results on the third and last session of the program in April 2019 with positive outcomes. Conclusions: The QTP’s quality improvement approach allows Spanish teams and the ECO Foundation to enhance the goal of a quality-oriented health care system. ECO will continue pursuing excellence and quality with further initiatives like the QOPI program, the QCP and the QTP.