POS1590-HPR ASSOCIATION OF SELF-PERCEIVED ORAL HEALTH STATUS WITH ESSPRI REPORTED BY PATIENTS WITH SJÖGREN’S SYNDROME
Authors: O. E. Alvarez-González, E. Quintana-Aguilar, H. Guerra, J. A. Cardenas-de la Garza, J. C. Riega-Torres, L. R. Aguilar Rivera, C. M. Skinner Taylor, D. Á. Galarza-Delgado
Journal: Annals of the Rheumatic Diseases (2023)

<h3>Background</h3> Salivary gland hypofunction, manifested as xerostomia in Sjögren's syndrome (SS), causes dental, language, and nutritional problems, leading to a detriment in oral health [1]. The Geriatric/General Oral Health Assessment Index Spanish Version (GOHAI-SP) is a useful tool that has been used to assess the self-perception of oral status in SS patients [2]. <h3>Objectives</h3> To describe oral health status using the GOHAI-SP in patients with primary (pSS) and secondary (sSS) Sjögren's syndrome and correlate it with EULAR SS Patient Reported Index (ESSPRI), Schirmer's test for both eyes and unstimulated salivary flow (USF). <h3>Methods</h3> A cross-sectional and observational study was conducted from October to December 2022 in the rheumatology service of the Hospital Universitario "Dr. José Eleuterio González", Mexico. Patients meeting ACR/EULAR criteria for pSS and sSS were included and assessed with ESSPRI and GOHAI-SP during their follow-up appointment or contacted by telephone. The latter index consists of 12 questions on a 1 to 5 Likert-type scale. The lowest obtainable score is 12 and the maximum 60. Scores ≤ 44 were classified as poor oral health, moderate from 45 to 50, and good ≥ 51. Questions 1-4 assesses oral functionality, 6, 7, 9-11 psychosocial status; 8 and 12 for pain. Objective data such as Schirmer's test and USF/15 minutes were obtained from patients' charts. <h3>Results</h3> A total of 41 patients were included: 31 (75.6%) with pSS and 10 (24.4%) with sSS most of whom were woman (n=40, 97.6%) with a mean age of 53.41 (SD: 12.58). The median score of GOHAI-SP was 50 [IQR 43.5-52], medians for dryness, fatigue, and pain reported in ESSPRI domains were: 3 [0-7], 2 [0-6.5] and 1 [0-5]; for Schirmer test 5 [1-16] and 10 [3-17.5] in right and left eyes respectively and USF 1.5 [0.5-2.25]. The self-perceived health status was classified as good in 19 (46.3%), moderate and poor both in 11 (26.8%). We found that the worse the self-perceived oral condition, the higher ESSPRI medians for dryness (p &lt;0.001), fatigue (p 0.003) and pain (p 0.002) were reported. No significant differences were found when compared to Schirmer and USF tests. Results for Spearman's correlation model are shown in Table 1. No significant differences were found between pSS and sSS groups. <h3>Conclusion</h3> The greater the severity of dryness, fatigue and muscular or joint pain, the greater the functional impairment of mouth and oral pain; as well as the worse the psychosocial aspect manifested as concern, nervousness, discomfort and limitation of interaction with people due to the dental appearance. <h3>References</h3> [1]Rusthen, S, Young, A, Herlofson, BB, Aqrawi, LA, Rykke, M, Hove, LH, Palm, Ø, Jensen, JL, Singh, PB. Oral disorders, saliva secretion, and oral health-related quality of life in patients with primary Sjögren's syndrome. <i>Eur J Oral Sci</i> 2017; 125: 265– 271. © 2017 Eur J Oral Sci [2]Leung KC, McMillan AS, Wong MC, Leung WK, Mok MY, Lau CS. The efficacy of cevimeline hydrochloride in the treatment of xerostomia in Sjögren's syndrome in southern Chinese patients: a randomised double-blind, placebo-controlled crossover study. <i>Clin Rheumatol</i>. 2008;27(4):429-436. doi:10.1007/s10067-007-0723-x <h3>Disclosure of Interests</h3> None Declared.