tbuckley/cabot-search huggingface dataset:
The hospice movement
Authors: S. A. Lack
Journal: JAMA (1979)

<h3>To the Editor.—</h3> The EDITORIAL "The Hospice Movement" by John P. Callan, MD (241:600, 1979), inThe Journaladdresses relevant issues but contains inaccuracies and reflects misconceptions. The hospice movement does not want "care of the dying... [to] be excluded from the mainstream of medicine." In fact, our ultimate goal is reincorporation of timeless values and accepted methods into general medical care. Technologically specialized curative medicine has catalyzed the growth of hospice medical care as a natural balance. Part of our responsibility and commitment is to educate health professionals that a "care system" can coexist with the "cure system." This requires fundamental changes in attitude; to this end, the Hospice Education, Training, and Research Foundation has been incorporated in New Haven, Conn. Until these ultimate goals are realized, hospice care remains the only way to get competent and compassionate terminal medical care from a multidisciplinary team of paid and volunteer
The Heimlich maneuver and the resuscitation of near-drowning victims
Authors: Joseph P. Ornato
Journal: JAMA (1986)

<h3>In Reply.—</h3> The new standards and guidelines for cardiopulmonary resuscitation and emergency cardiac care<sup>1</sup>restrict the use of the Heimlich maneuver in the management of near-drowning victims to only those circumstances in which the rescuer suspects that foreign (particulate) matter is obstructing the airway. If the victim does not respond appropriately to mouthto-mouth ventilation, the rescuer is permitted to try a Heimlich maneuver on the grounds that a foreign-body obstruction may have been overlooked. The standards specifically state that "any attempt to remove water from the breathing passages by any means other than suction may be unnecessary and dangerous because it could eject gastric contents and cause aspiration" (p 2929). The reason for the restriction is that there is inadequate scientific evidence to support the safety or efficacy of the Heimlich maneuver in this setting. Controlled studies have not shown that the Heimlich maneuver is useful in freshwater near-drowning.
Reducing high blood cholesterol level with drugs. Cost-effectiveness of pharmacologic management
Authors: K. A. Schulman
Journal: JAMA (1990)

We performed a cost-effectiveness analysis of pharmacologic treatment of high blood cholesterol levels. Agents modeled were cholestyramine, colestipol, gemfibrozil, lovastatin, niacin, and probucol. Pharmacologic effectiveness was estimated from reported studies. Cost estimates reflect societal resource consumption. Annual costs for therapy ranged from $327 (niacin) to $1881 (lovastatin, 80 mg/d). Niacin was the most efficient agent for reducing low-density lipoprotein cholesterol levels, having an average cost over 5 years of $139 per percent reduction in low-density lipoprotein cholesterol level. Lovastatin (20 mg/d) was also efficient ($177 per percent reduction). Cholestyramine was least efficient at $347. For high-density lipoprotein cholesterol, niacin was most efficient, at $116 per percent increase in high-density lipoprotein cholesterol level, followed by gemfibrozil at $271. Analyses combining low-density lipoprotein cholesterol and high-density lipoprotein cholesterol effects suggest that niacin and lovastatin (20mg/d) were most efficient for reducing cardiovascular risk. (<i>JAMA</i>. 1990;264:3025-3033)
Abstract 13267: Advanced Heart Failure With Reduced Ejection Fraction and Severe Mitral Insufficiency Compensate With a Higher Oxygen Peripheral Extraction to a Reduced Cardiac Output vs Oxygen Uptake Response to Maximal Exercise
Authors: Greta Generati, Francesco Bandera, Marta Pellegrino, Valentina Labate, Francesco Carbone, Eleonora Alfonzetti, Marco Guazzi
Journal: Circulation (2015)

Background: in heart failure (HF) the mitral regurgitation (MR) is clinical and prognostic relevant. Cardiopulmonary exercise testing (CPET) allows evaluating functional capacity and provides indexes for HF risk stratification such as peak oxygen consumption (VO2). Since MR determines a severity-related backward flow to left atrium, it may result in an unfavorable central blood flow exercise redistribution that is physiological relevant to VO2 increase. Aim: To evaluate the cardiac output (CO) and VO2 exercise-response in HF reduced ejection fraction (HFrEF) patients according to MR severity to dissect what mechanism may be predominant in the VO2 increase. Methods: 104 HFrEF patients (mean age 64±11 y, male 72%, ischemic etiology 68%, mean LVEF 34±9%) underwent a maximal CPET (incremental ramp protocol) combined with exercise-echo. CO was non-invasive estimated by echo. Results: Population was divided into 2 groups according to the rest MR: group A (n=80) non-severe MR and B (N=24) severe MR. Despite the groups did not differ in rest CO (A vs B 3.8±1 vs 3.4±1.8 L/min, p=ns) and VO2 (0.27±0.06 vs 0.28±0.09 L/min, p=ns) group B showed higher peripheral extraction (C(a-v)O2 8±2 vs 9±4 mL/100 mL, p=0.036) already at rest (Figure). At peak exercise group B had an impaired increase both in CO (7,0±2,0 vs 5,2±3,3 L/min) and VO2 (1,0±0,3 vs 0,8±0,3 L/min, p=0.001) partially compensated by a greater C(a-v)O2 contribution (15±4 vs 18±5 for A vs B, p=0.047). Conclusions: Severe MR and consequent partial abnormal CO redistribution to the pulmonary circulation seems a relevant pathophysiological mechanisms that limits overall exercise performance in HFrEF. In this high risk subset of patients peripheral extraction compensates for the reduced CO and makes the basis for novel perspectives in these patients.
Methylenedioxyphenyl Insecticide Synergists as Potential Human Health Hazards
Authors: Michael R. Franklin
Journal: Environmental Health Perspectives (1976)

The effects of methylenedioxyphenyl insecticide synergists on human health arise, not from their intrinsic toxicity which is relatively low, but from their dual effect on the oxidative detoxication or intoxication processes of the body. They are able to inhibit these reactions by two mechanisms. They are substrates for mixed function oxidation and, thus, compete with other xenobiotics for available enzyme, and an intermediate in their metabolism is able to bind with cytochrome P-450 to form an inactive complex which absorbs maximally at 455 nm. In addition, they are able to activate xenobiotic metabolism by induction (the increased synthesis and retention) of microsomal oxidative enzymes. Evidence for these effects is presented, including spectroscopic and enzyme kinetic data. Correlations with existing in vivo observations are outlined. The inhibition and induction of cytochrome P-450, the central enzyme in the metabolism of xenobiotics, thus provides the focus for consideration of methylenedioxyphenyl synergists as potential hazards.
Loiasis
Authors: Sven Kalbitz, Thomas Grünewald
Journal: New England Journal of Medicine (2021)

A 36-year-old woman presented with a moving wormlike structure in her left eyelid (shown in videos). Microscopic examination of a fresh-blood wet smear revealed fast-moving worms, and Giemsa-stained blood films confirmed the presence of microfilaria consistent with Loa loa.
THE QUESTION OF PHYSICAL EXAMINATION.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Noxious Fumes
Authors: M. R. Zavon
Journal: JAMA (1961)

<h3>To the Editor:—</h3> InThe Journal, Nov. 5, 1960, page 1358, Dr. Andrew L. Banyai, in replying to a question regarding the treatment of a feeling of recurrent suffocation in a refrigerator installer, suggested the use of certain specific medicaments. I would have no quarrel with the treatment indicated, but I do question the implication in the reply that treatment of the complaint is by means of drugs. The primary treatment in such a situation is control of the exposure, which is not necessarily by discontinuation of the man's occupation. Inasmuch as all refrigerator installers do not have this same complaint, it would seem that exposure to the material mentioned in the original question is not a necessary part of this job and that methods of control can be established. This is the primary treatment of the complaint. Drug treatment can only be palliative.
Infections Involving Implantable Cardiac Devices
Journal: Annals of Internal Medicine (2000)

Summaries for Patients17 October 2000Infections Involving Implantable Cardiac DevicesSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-133-8-200010170-00006 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Implantable cardiac devices are electronic instruments placed under the skin, from which wires (called “leads”) go into the heart. These devices include pacemakers and cardioverter defibrillators, which are used to treat abnormal heart rhythms. Implantable cardiac devices, like any device that is placed in the body, can become infected. Infections involving implanted devices usually do not get better unless the device is removed. Removing the leads for pacemakers and cardioverter defibrillators can create problems, however, so the best approach to treatment when those devices become infected is not ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Diagnosis and Management of Infections Involving Implantable Electrophysiologic Cardiac Devices.” It is in the 17 October 2000 issue of Annals of Internal Medicine (volume 133, pages 604-608). The authors are JD Chua, BL Wilkoff, I Lee, N Juratli, DL Longworth, and SM Gordon.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoDiagnosis and Management of Infections Involving Implantable Electrophysiologic Cardiac Devices Jimmy Dy Chua , Bruce L. Wilkoff , Irene Lee , Nour Juratli , David L. Longworth , and Steven M. Gordon Metrics 17 October 2000Volume 133, Issue 8Page: I-51KeywordsAntibioticsCardiac electrophysiologyHeartHospitalsPacemakersPatientsSkin infections ePublished: 17 October 2000 Issue Published: 17 October 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
THE CHEMIST A PROFESSIONAL MAN.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Education About Drug Abuse in Medical Schools
Journal: JAMA (1972)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Growth hormone neurosecretory dysfunction. A treatable cause of short stature
Authors: B. E. Spiliotis
Journal: JAMA (1984)

Pulsatile growth hormone (GH) secretion was assessed in a subgroup of short children to determine whether they had GH secretory abnormalities, and these results were compared with those of normal and GH-deficient children. This subgroup of children was defined as having GH neurosecretory dysfunction and met the following criteria: height, less than first percentile; growth velocity, 4 cm/yr or less; bone age, two or more years behind chronological age, normal findings from provocative GH tests (peak, ≥10 ng/mL), low somatomedin-C level, and abnormal 24-hour GH secretory patterns. When compared with controls, both children with GH neurosecretory dysfunction and GH-deficient patients had a significant decrease in parameters relating to the total GH secretion during the 24-hour period. As with GH-deficient children, the group with GH neurosecretory dysfunction more than doubled their growth velocity after replacement therapy with exogenous human GH during the first year of treatment. As a result of these detailed studies on pulsatile GH secretion, we suggest that there is a spectrum of GH secretory abnormalities from absolute deficiency to an intermittent irregularity in GH secretion. (<i>JAMA</i>1984;251:2223-2230)
Hepatic Amoebiasis
Authors: M. Thomas
Journal: BMJ (1964)

Feet and FashionSiRs-In connexion with your leading article " Feet and Fashion " (21 November, p. 1282), some figures concerning the epidemiology of fashion may be of interest to your readers.During school medical inspection in 1964 I have recorded the footwear of children in infant, junior, and secondary modern schools in Lancashire.The following Table shows the results.The figures are
A Union Meeting of the District Medical Societies of Northern Ohio.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fashions in infant feeding.
Journal: BMJ (1973)

Fashions in Infant FeedingIs malnutrition affecting the health of British babies?The severe undernutrition that stunts the growth of so many children in the world is now a matter of growing international concern, not least because undernutrition during infancy can permanently affect the rapidly growing brain.'But there are those who would argue that our babies are now being overfed.Malnutrition is not synonymous with undernutrition.Recent surveys from Worcestershire2 and South York- shire3 show that babies are growing more rapidly than 20 years ago, but there is, of course, no a priori reason for assuming that infant growth was then optimal.The national standard against which we at present judge the growth of preschool children4 was based on a random sample of 80 children of each sex who were taken into a longitudinal survey in central London during 1949-1954.5It would seem that more than 40% of healthy babies now weigh over 7 kg (151 l,b) at 3 months whereas less than 10% weighed as much as this 20 years ago.But there is no sustained increase in the rate of skeletal growth in these babies after 3 months, so the increase in weight is not accompanied by any lasting increase in height.2Sometimes the babies who
Audits of antimicrobial usage. 2. Nonsurgical prophylaxis
Journal: JAMA (1977)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Environment
Authors: J. H. Lehmann
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Probable herpes simplex pneumonia after aortic valve replacement
Authors: R. H. Breyer
Journal: JAMA (1983)

Herpesvirus pneumonia developed in a 68-year-old man after aortic valve replacement and two-vessel aortocoronary bypass. The complication was fatal, and the diagnosis was made only after death. The source of the herpesvirus could not be determined. (<i>JAMA</i>1983;249:1319-1322)
Treatment of Herpesvirus Infections
Authors: Jan Koch-Weser, Martin S. Hirsch, Robert T. Schooley
Journal: New England Journal of Medicine (1983)

CytomegalovirusCytomegalovirus is a major cause of congenital malformations and an important opportunistic pathogen in immunocompromised hosts.112 In transplant recipients, it may cause interstitial pneumonitis, fever–leukopenia syndromes, hepatitis, glomerulopathy, retinopathy, and other disorders, and may enhance susceptibility to superinfection with fungi, protozoa, and bacteria.113 , 114 It also causes a heterophil-negative mononucleosis syndrome in both immunocompetent and immunosuppressed hosts.115 , 116 No agent has shown clinical usefulness in the therapy of cytomegalovirus infection. Therapeutic trials in ongoing cytomegalovirus pneumonia have been carefully conducted in bone-marrow–transplant recipients in Seattle.117 , 118 Treatment with vidarabine, alpha interferon, acyclovir, and combinations of vidarabine and alpha interferon or of acyclovir . . .