tbuckley/cabot-search huggingface dataset:
Death of Diana, Princess of Wales
Authors: E. R L Williams, J. Meadows, J. Catal, M. Shevlin, V. Brunsden, S. Walker, M. Davies, T. Ramkalawan
Journal: BMJ (1997)

Progress in reducing inpatient mortality from acute myocardial infarction is slowEditor-Brown et al report a substantial increase in the use of beneficial interventions for patients admitted to hospital with acute myocardial infarction in Nottingham from 1982 to 1992. 1 However, they found no change in inpatient mortality adjusted for age and sex.This contrasts with findings in Ontario, Canada, where hospital discharge abstracts show that inpatient mortality fell from 1981 to 1991 2 and has since fallen further (data on request).Brown et al suggest that the disparate results may reflect coding errors in the Ontario administrative data.Our group has assessed the classification of deaths from acute myocardial infarction in inpatients in the Ontario discharge abstracts.Matching Ontario administrative data to data from the GUSTO-I and LATE trials, we found the specificity of the administrative data to be 100% (1403/1403 alive), with overall sensitivity of 94% (104/111 deaths detected). 3he classification of acute myocardial infarction itself is more problematic.The sensitivity of the primary diagnosis of acute myocardial infarction is high, but specificity varies. 4 5There are two common reasons for false positive coding.Firstly, patients may be admitted to a coronary care unit with possible acute myocardial infarction but this diagnosis is ruled out and they are sent home quickly.Alternatively, patients recently admitted to hospital with acute myocardial infarction are readmitted for coronary angiography or with complications other than overt reinfarction, and the code for acute myocardial infarction is wrongly used again.Thus the analysis of outcomes in Ontario excluded both patients with a primary diagnosis of acute myocardial infarction who were discharged in under four days and patients who had been admitted to hospital for acute myocardial infarction in the preceding three months. 2t is therefore doubtful that imprecise coding explains the improving outcomes of acute myocardial infarction in Ontario.Indeed, only systematic coding errors could explain the observed trends in inpatient mortality, and we have found neither evidence nor a rationale for this.Ontario's administrative data do mirror the findings of Brown et al in two respects 2 : admissions for acute myocardial infarction, particularly among elderly patients, increased over the period studied, and inpatient mortality ranged from 16% to 21%, which is much higher than in the large randomised trials of thrombolytic treatment.Thus while the trends in Ontario are more positive than those in Nottingham, we agree with Brown et al that the cardiovascular megatrials have been enrolling skewed patient populations 3 and that progress in the battle to reduce inpatient mortality from acute myocardial infarction remains slow.
Mall de Pott
Authors: TAMER ATASEVER, AYFER SOYLU, MELIHA KORKMAZ, GULSEREN ARAS, MEHMET DEMIRTAS, GUNER ERBAY
Journal: Clinical Nuclear Medicine (1993)

Tc-99m hexamethylpropylene amineoxime (HMPAO) leukocyte and bone images were taken of a 25-year-old man who complained of lower back pain for 2 years. Severe vertebral body destruction was found during the subsequent operation. Tuberculosis was reported as a result of histopathologic examination.
Outlines of Industrial Medical Practice
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Оснащення ультразвуковими апаратами лікувальних закладів України та його вплив на показники захворюваності на хвороби біліарної системи
Authors: І.Yu. Skyrda, O.P. Petishko, T.I. Panteleyeva
Journal: GASTROENTEROLOGY (2014)

У статті наведено дослідження впливу оснащення ультразвуковим обладнанням на показники захворюваності на хвороби біліарної системи із застосуванням методів кореляційного та регресійного аналізів. У дослідженні проаналізовано ресурсні показники ультразвукової діагностики, а також захворюваності на жовчнокам’яну хворобу, хронічний холецистит і холангіт, гострий холецистит згідно з офіційними даними Центру медичної статистики МОЗ України в 25 областях України протягом 7 років (2006–2012). Загальна кількість об’єктів дослідження дорівнювала 175.У рамках дослідження вивчено вплив фондоозброєності на показники захворюваності на гострий холецистит. Фондоозброєність праці медичного персоналу — показник, що характеризує рівень технічної оснащеності трудових процесів, величину основних виробничих фондів, що розраховуються на одного медичного працівника. Приріст показника фондоозброєності ультразвуковими апаратами за досліджуваний період у цілому в Україні становив 70,1 %. Такий приріст спричинювало зростання балансової вартості медичного обладнання через збільшення обсягу закупівель медичної техніки при відносно стабільній штатній чисельності лікарів. Коефіцієнт використання парку ультразвукових апаратів за останні 7 років збільшився з 0,82 до 0,86.Поширеним ускладненням жовчнокам’яної хвороби залишається гострий холецистит, що в екстреній хірургії за частотою займає друге місце після гострого апендициту. За останні 7 років в Україні відзначається збільшення кількості випадків цього захворювання в 1,3 раза. Встановлено статистично значущий вплив фондоозброєності лікаря ультразвуковим устаткуванням на кількість випадків гострого холециститу.
IMPACT OF BIFURCATION ANGLE ON MAJOR CARDIAC EVENTS AFTER CROSS OVER SINGLE STENT STRATEGY IN UNPROTECTED LEFT MAIN BIFURCATION LESION: 3-DIMENSIONAL QUANTITATIVE CORONARY ANGIOGRAPHIC ANALYSIS
Authors: Amamiya Kisaki, Takenori Domei, Masashi Iwabuchi, Masakiyo Nobuyoshi
Journal: Journal of the American College of Cardiology (2012)
Vulvodynia Common
Authors: Brian Vastag
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Risperidone and Neuroleptic Malignant Syndrome
Authors: Daniel Tarsy
Journal: JAMA (1996)

<h3>To the Editor.</h3> —Risperidone is a relatively new antipsychotic drug that differs from traditional neuroleptic medications in several important ways. It is a benzisoxazole derivative that blocks dopamine D<sub>2</sub>and serotonin type 2 receptors and binds to α-adrenergic and histamine H<sub>1</sub>receptors.<sup>1</sup>The incidence of extrapyramidal side effects appears to be dose dependent and has been only slightly higher than placebo in the recommended dose of 6 mg/d or less.<sup>1</sup>We report a case of neuroleptic malignant syndrome that appeared within several days of initiation of risperidone. <h3>Report of a Case.</h3> —A 43-year-old woman with chronic schizophrenia and depression was hospitalized for increasing depression, withdrawal, and paranoid ideation. She had been hospitalized and treated in the past with antipsychotic and antidepressant medications without adverse neurologic effects. Recent treatment with clozapine and sertraline hydrochloride was ineffective, and she was admitted for electroconvulsive therapy. She received two unilateral
Current Medical Literature
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Highlights of This Issue
Journal: Clinical Cancer Research (2013)

KRAS hyperactivation can occur through mutation or genomic amplification and defines a subset of lung tumors with poor prognosis and fewer therapeutic options.McCleland and colleagues utilize both functional and genomic techniques to identify genes that functionally cooperate with KRAS.These integrative approaches identify lactate dehydrogenase B (LDHB) as overexpressed and necessary for cell growth in the context of KRAS-hyperactive lung cancers.Consistent with a role for LDHB in glycolysis and tumor growth, lung cancers with high LDHB show an increased dependence on glycolysis and a worse patient outcome.These findings warrant further investigation of LDHB as a metabolic driver in KRAS-dependent lung cancer.
Some Canadian Contributions to Medicine
Authors: William C. Gibson
Journal: JAMA (1967)

In this special issue ofThe Journaldedicated to Canada's 100 years of confederation, certain special fields are discussed. The remaining areas of interest cannot be encompassed in a single paper by a single author, but in this communication, a broad spectrum of Canadian contributions will be reviewed. <h3>Exports</h3> Canada's position as a world trader has not been achieved by exporting lumber, fish, and minerals alone. For the past century, Canada has been exporting trained men, and the field of medicine has been no exception. In many cases, Canadian physicians found opportunities abroad to develop, in metropolitan centers, ideas which they had generated under relatively frontier conditions. Perhaps out of sheer necessity, Canadians have developed organizational talents through having to cover large fields unaided. Often, no division of labor could be afforded so that Canadians were more likely to be all-embracing generalists than narrow specialists. As individuals, their horizons were
Long-term Eradication of Chlamydia trachomatis Genital Infection After Antimicrobial Therapy
Authors: Kimberly A. Workowski
Journal: JAMA (1993)

<h3>Objective.</h3> —To determine whether<i>Chlamydia trachomatis</i>urogenital infections persist or relapse after antimicrobial therapy by serial measurement of chlamydial-specific DNA using the polymerase chain reaction (PCR), cell cultures, and serological studies. <h3>Design.</h3> —Prospective evaluation of an inception cohort. <h3>Setting.</h3> —University student health clinic. <h3>Participants.</h3> —Twenty women with culture-proven and PCR-proven<i>C trachomatis</i>urogenital infections. <h3>Measurements.</h3> —Incidence of persistent infection as determined by PCR, culture, and serial measurement of local and systemic antibody to<i>C trachomatis</i>for 5 months after doxycycline therapy. <h3>Results.</h3> —Prior to therapy,<i>C trachomatis</i>was isolated in cell culture from the cervix in 19 of 20 women, from the urethra in 13 women, and from the rectum in 13 women. All culture-positive specimens were also PCR-positive. Immediately after completion of antimicrobial therapy, all women had negative cell cultures for chlamydia. Ten of 20 culture-negative cervical specimens and two culture-negative urethral specimens had chlamydial DNA present immediately after treatment. In addition, three women had detectable DNA from cervical specimens 1 week after treatment. The presence of cervicitis (<i>P</i>=.01), high inclusion counts (<i>P</i>=.004), and serological evidence of recent infection (<i>P</i>=.0004) were each significantly associated with PCR positivity after treatment. All 384 subsequent cervical, rectal, and urethral specimens collected over 5 months were negative by both PCR and culture with the exception of one woman who was reinfected. Serum immunoglobulin M (IgM) titers, geometric mean serum immunoglobulin G (IgG) titers, and prevalence of local antibody to chlamydia progressively declined after treatment. <h3>Conclusions.</h3> —Standard antimicrobial therapy is effective in the long-term microbiologic eradication of uncomplicated<i>C trachomatis</i>urogenital infections. The presence of chlamydial DNA after antimicrobial therapy is of short duration and reflects excretion of nonviable organisms rather than persistent infection. (<i>JAMA</i>. 1993;270:2071-2075)
Handbuch der Experimentellen Pharmakologie.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Awards, Appointments, Announcements
Journal: JNCI Journal of the National Cancer Institute (1992)

Awards, Appointments, Announcements Get access JNCI: Journal of the National Cancer Institute, Volume 84, Issue 13, 1 July 1992, Pages 1006–1007, https://doi.org/10.1093/jnci/84.13.1006 Published: 01 July 1992
HOSPITAL FORMULARY SYSTEM
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Patients' Acceptance of Physician's Assistants
Authors: Eugene C. Nelson
Journal: JAMA (1974)

Patients of physicians using physician's assistants in their practices were surveyed to determine attitudes toward these assistants. Fifty-four percent of the patients responded and 12% of the nonrespondents were interviewed to insure that respondents were representative of the sample. Patients rate the physician's assistants highly in terms of technical competence (89%), professional manner (86%), and report improvements in the quality of care (71%) and access to services (79%), since the physician's assistants began working. Eighty-seven percent of the patients who received physical examinations from physician's assistants were very satisfied. Patient's age, social class, and access to medical services are significantly related to certain attitudes toward physician's assistants. (<i>JAMA</i>228:63-67, 1974)
Possible platelet syndrome suggested in early stroke
Authors: William A. Check
Journal: JAMA (1984)

Neurologists in Detroit have found a group of young patients with stroke whose ischemic events seem to be caused by platelets that aggregate too easily. Some of these patients also have a history of migraine headaches and most come from families with histories of migraine headaches or early heart attacks and stroke. Treating these patients with a drug regimen that inhibits platelet aggregation and having them stop smoking cigarettes has proved to be successful therapy so far for preventing further strokes. <h3>Young Patients and Sticky Platelets</h3> These findings were reported at the Ninth International Joint Conference on Stroke and Cerebral Circulation, Tampa, Fla, by neurology resident Patti L. Holliday, MD, of the Wayne State University School of Medicine, Detroit. Holliday, fellow neurology resident John Buday, MD, and John Gilroy, MD, chair, Department of Neurology, have identified 15 persons between the ages of 9 and 47 years (mean age, 26 years)
Lead Thirteen Electrocardiography
Authors: U. R. Shettigar
Journal: JAMA (1973)

<h3>To the Editor.—</h3> In a LETTER TO THE EDITOR (224:1533, 1973) entitled " `Lead Thirteen' Electrocardiography," Dr. Sanford Lewis makes a plea for the routine recording of lead III during deep inspiration to differentiate between abnormal Q waves indicating diaphragmatic infarction and benign Q waves. Q waves persisting during inspiration are regarded as due to diaphragmatic infarction. We disagree with this recommendation. In our experience this maneuver has not been helpful in distinguishing abnormal Q waves due to diaphragmatic myocardial infarction from benign Q waves. A Q wave is considered abnormal if it is 0.04 seconds or more in duration and at least 25% of the QRS voltage (amplitude) It is true that in many individuals a Q wave in lead III may disappear or become insignificant on deep inspiration. This, however, does not always establish the benign nature of the Q wave, since a marked number of patients with well-established
'Venice' Is Not Sinking (The Water Is Rising)
Authors: Donald S. Fredrickson
Journal: JAMA (1982)

<h3>Scientific Freedom and Public Interest</h3> In a country like the United States with a highly educated population, an active press, and diversity of culture and opinion, openness is both possible and indispensable in considering the implications of a subject like biomedical research. This is illustrated in the recent, but now cooling, debates over the use of technology for genetic recombination. The results can be extrapolated to other kinds of highly charged scientific and medical dilemmas that face society. The National Institutes of Health (NIH) was the primary focus of the recombinant DNA debate, but other federal agencies, Congress, many communities, public interest groups, and industry were all involved. In our deliberations at the NIH, we actively sought all information that might bear on the putative future hazards of recombinant DNA research. We learned many things. These did not include new scientific data that made the hypothetical risks more likely than
THC or analogues may alleviate some tremors
Authors: Phyllis Gapen
Journal: JAMA (1982)

Tetrahydrocannibinol (THC), a major active ingredient of marijuana, suppressed tremors in two of eight patients with multiple sclerosis (MS), reported neuropharmacologist David Clifford, MD, at the recent annual meeting of the American Neurological Association in Washington, DC. In a study conducted at Washington University School of Medicine in St Louis, where Clifford is assistant professor of neurology, 5 mg of Δ<sup>9</sup>-THC was administered orally to eight MS patients suffering from disabling tremors and ataxia. The ages of the four men and four women ranged from 21 to 49 years. The dosages were increased by 5-mg increments everysix hours until therapeutic responses or adverse effects occurred. Samples of THC were obtained from the National Institute on Drug Abuse, Rockville, Md. Subjective and objective improvement were reported in two of the eight patients; this did not occur when a placebo was used in the single-blinded experiment. Clifford said the most