tbuckley/cabot-search huggingface dataset:
Incorrect Text
Journal: JAMA (2001)

To the Editor: Several US state medical boards or legislatures have begun drafting regulations that would limit surgical procedures that could be performed in physicians' offices.Although such efforts are often motivated by sensational accounts in the popular press, there are little available data on the incidence of injuries that occur in such settings. 1Methods.In February 2000, the state of Florida mandated that physicians report all office incidents that resulted in death, brain damage, or spinal damage or that included a procedure that was performed on the wrong person, a procedure to remove an unplanned foreign object left from a preceding surgical procedure, any condition that required transfer of a patient to a licensed hospital, a surgical procedure performed on wrong site, wrong surgical procedure being performed, or surgical repair of injuries or damage from a planned surgical procedure.Data collected by the Florida Agency for Health Care Administration are the source for this report.To minimize underreporting, all filed malpractice cases and spontaneous complaints are checked against the database.Physicians who do not report an incident are investigated and may face sanctions (Margaret Beck, investigation specialist for the Florida Agency for Health Care Administration, oral communication, March 2001).I contacted all offices reporting surgical incidents or deaths in the 12 months that began in February 2000, and determined physician hospital privilege and office accreditation status.Physician specialty certification status was determined via Internet sites, available at http://www.abms.org/newsearch.aspand www.abms.org/newsearch.asp.The actual incident reports, as well as a summary table, are available at www.salu .net/brettcoldiron.Results.Of the 55 reports recorded in the 12-month period, 24 neither involved a procedure nor resulted in death.These offices were not contacted.This left 31 procedurerelated complications or deaths that involved 28 physicians.Although use of local and regional anesthesia had few serious complications, 2 anaphylactic reactions were reported.No complications involving tumescent (dilute local) anesthesia were reported.There were 7 incidents during or after intravenous sedation, but no deaths occurred.One of the incidents may have been related to the intravenous sedation.Fourteen of the 31 procedural complications occurred in offices accredited by an independent accrediting agency.Two other offices were in the process of obtaining office accreditation.Twenty-seven of 28 physicians reporting incidents (3 physicians had 2 incidents each) were board certified in their respective specialty and 27 of 28 had hospital privileges.All physicians appeared to be operating within the parameters of their reported specialties.
Should prematiral syphilis serologies continue to be mandated by law?
Authors: Y. M. Felman
Journal: JAMA (1978)

ONE OF the screening tests that has been used to measure the extent of communicable syphilis in a population is the premarital syphilis serology that is mandated by law in most states. Approximately 4 million serologies are performed annually in the United States for this purpose.<sup>1</sup>In New York City, according to the Office of the City Clerk, 57,994 marriage licenses were issued in 1976. Therefore, about 116,000 premarital syphilis tests were performed. For some time, the Bureau of Venereal Disease Control of the New York City Health Department has been exploring whether this screening test has a meaningful impact on syphilis control. For a screening program to be considered cost-effective, the disease screened should be of serious or catastrophic consequence and easily preventable or treatable, and the cost of the screening test itself should be negligible. Screening for hypertension and glaucoma fulfills these requirements well. On the other
FOREIGN CORRESPONDENCE.
Authors: None G. O. M.
Journal: JAMA (1883)

London, November, 1883. By the somewhat sudden death of Sir William Siemens, the scientific world loses one of its brightest luminaries. He was by birth a German, and learned engineering at the factory of Count Stolberg, but in 1843 he came to England. Since then, his fertile brain produced invention after invention, each fresh outcome of his inventive power having some practical bearing on the arts. He received the degree of D.C.L. from Oxford University in 1869; was elected a Fellow of the Royal Society in 1862. His theory of the conservation of solar energy, published last year, won the attention of men of science all over the world. At the last meeting of the Pathological Society, Mr. Sutton, in conjunction with Dr. H. Gibbes, read a paper on " Tuberculosis in Birds." He said his attention was first attracted to the disease by a farmer in the north of Middlesex,
DEGENERACY.
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TYPES OF CHILDREN.
Authors: W. S. CHRISTOPHER
Journal: JAMA (1904)

There is a condition found in new-born babies, and usually confounded with sepsis neonatorum, which seems to me to be entirely autotoxic in character. This condition is often manifested on the first day of life, but may be delayed two or three days. The symptoms are vomiting, cardiac depression, poor circulation, frequently cyanosis, irregular and weak respiration, convulsions in the severer cases, and special symptoms on the part of the bowels and skin. The stools, which are generally frequent, do not become yellow, but remain green, and contain considerable mucus. A peculiar skin eruption appears about the third day, but may be delayed for a week or even more. This eruption consists of pustules, so small that their pustular character is often overlooked. These pustules are located principally on the upper portion of the chest, the neck and chin, and in the bends of the elbows. About each pustule is
Herpes zoster infection and use of oral anticoagulants. A potentially dangerous association
Authors: B. Blumenkopf
Journal: JAMA (1983)

ORAL ANTICOAGULANTS are currently approved for the secondary prophylactic treatment of venous thrombosis and pulmonary embolism and for the cerebral thromboembolic complications that typically result from mitral valve disease with atrial fibrillation. Hemorrhagic episodes are the main untoward effects caused by therapy with these agents. Accordingly, their usage must be carefully monitored by the determination of the one-stage prothrombin time. However, bleeding may occur even when this time is within the accepted therapeutic range. Spinal subdural hematomata are rare neurosurgical emergencies. These have been described as a complication of anticoagulant therapy, following spinal injury, or as being "spontaneous" in origin.<sup>1,2</sup>A patient receiving oral anticoagulants had development of an acute spinal subdural hematoma and subarachnoid hemorrhage during the course of a thoracic level herpes zoster infection. The clinical presentation and subsequent course suggested to us the potentially dangerous association of herpes zoster infection and anticoagulant therapy. <h3>Report of a</h3>
Medicine, Business
Authors: Michael S. Wilkes, Jerome R. Hoffman
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ultra-deep next-generation sequencing of plasma cell-free (cf) DNA from patients with advanced cancers.
Authors: Filip Janku, Kiran Madwani, Shile Zhang, Helen J. Huang, Debra L. Andrews, David S. Hong, Daniel D. Karp, Siqing Fu, Xuyu Cai, Yue Zhao, Jian-Bing Fan, Jill Waters, Jonathan Toung, Li Liu, Min-Jui Richard Shen, Gordon B. Mills, Neeraj Salathia
Journal: Journal of Clinical Oncology (2016)

11537 Background: Plasma cfDNA offers an easily obtainable source of DNA for molecular analysis, which provides an attractive alternative to tumor tissue testing. Novel ultrasensitive multiplex technologies are needed for further implementation of cfDNA testing in personalized cancer therapy. Methods: We have developed an ultra-deep next-generation sequencing method for detection of somatic alterations in up to 62 common cancer related genes in plasma cfDNA. Each cfDNA fragment was uniquely barcoded and amplified prior to Illumina target enrichment workflow, followed by ultra-deep sequencing ( > 10,000X). Proprietary data processing and analysis tools were developed to enable sensitive detection of rare mutant molecules over high wild-type background (detection of 1 in 1,000 - 10,000 molecules). Results were compared to molecular profiling of archival primary or metastatic tumor tissue obtained at different points of clinical care from a CLIA-certified laboratory. Results: Plasma cfDNA was extracted from 61 patients with advanced cancers (colorectal, n = 16; non-small cell lung [NSCLC], n = 12; breast, n = 6; melanoma, n = 4; cholangiocarcinoma, n = 3; thyroid, n = 3; ovarian, n = 3; pancreatic, n = 3; appendiceal, n = 2; cervical, n = 2; glioma, n = 2; other, n = 6) and for the presence of alterations in up to 62 common cancer related genes. Ultra-deep sequencing of plasma cfDNA detected key driver molecular alterations reported from archival tumor tissue samples in 66% (41/62) cases and absolute agreement between utra-deep sequencing of plasma cfDNA and archival tumor tissue was reported 53% (33/62) cases. There were no disagreements in samples from patients with cholangiocarcinoma, cervical, ovarian and pancreatic cancer, while none of the plasma cfDNA samples from patients with glioma revealed molecular alterations detected in the tumor tissue. Conclusions: Detecting common oncogenic alterations using ultra-deep sequencing of plasma cfDNA is feasible and should be further investigated for testing in patients with advanced cancer.
Continuing Medical Education
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pulmonary Medicine
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hypoglycaemia
Authors: Piya Sen Gupta, Andrea N Green, Tahseen A Chowdhury
Journal: BMJ (2011)

A 58 year old white man who has had type 2 diabetes for 10 years is concerned about increasingly frequent hypoglycaemic episodes, usually in the late afternoon. He has been taking a stable, once daily dose of basal insulin glargine 14 units for two years, as well as twice daily gliclazide 160 mg and metformin 1000 mg. His body mass index is 23 (weight (kg)/ (height(m)2)) and his weight is stable. He works in finance and has recently divorced. Hypoglycaemia can occur in diabetic patients treated with insulin or sulphonylureas. Most cases are caused by an imbalance between carbohydrate intake and hypoglycaemic treatment. Mild hypoglycaemia is common, although rarely problematic in people with tight glycaemic control, and can occur in people with poor glycaemic control owing to wide fluctuations in glucose concentrations. It is important to identify the underlying cause, as recurrent or severe hypoglycaemia can have serious consequences, such as injury to the patient or others, or serious cognitive dysfunction. To confirm hypoglycaemia a clear history is vital. The differential diagnosis should be considered, but diagnosing hypoglycaemia is straightforward if the three Whipple’s criteria are met:
Obstructive sleep apnea in Georgia family: is it hereditary?
Authors: J. Elliot
Journal: JAMA (1978)

A new study of obstructive sleep apnea in three adult male members of a single Georgia family adds to the growing evidence that the syndrome is controlled by a hereditary factor. The study, undertaken at the Gainesville (Fla) Veterans Administration Hospital, revealed episodic apnea, hypoventilation, and oxygen desaturation in one patient displaying classic sleep apnea as well as in his 9-year-old son and 32-year-old brother. Another brother of the index patient could not be studied, since he could not fall asleep during attempted polysomnography. Three daughters of the index patient were unavailable for evaluation. "Although we cannot prove a hereditary relationship in all instances of sleep apnea," said Robert A. Rostand, MD, formerly of the Department of Pulmonary Medicine at the Gainesville VA Hospital, "the case of this one family, where obesity, excessive snoring as well as altered neural control mechanisms have all been identified, strongly suggests a hereditary factor
Journal Amer Geriatrics Society, Baltimore
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE PUBLICATION OF PAPERS.
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Logistic regression
Authors: P. Sedgwick
Journal: BMJ (2013)

<h3>Introduction</h3> The overall trend of an increase in organ donation (OD) has not been replicated in the paediatric population. Individual units have wide variations in practice and raise the question of whether bespoke national strategies would contribute to the aim of increasing OD in this area. <h3>Method</h3> The UK has 27 paediatric intensive care units (PICU) on the potential donor audit (PDA). Individual unit data was extracted from Apr15–Mar16. Discussions were held with clinicians and specialist nursesorgan donation (SNODs) from units regarding practices. <h3>Results</h3> 93% of children &lt;16 years that met a referral criteria died in PICU, 92% of eligible donors were also in PICU. Nationally neurological determination of death (NDD) was suspected in 90 cases, 59 NDD tests performed. 111 (61%) eligible donors were approached. Non identification was the reason for non approach in 16 (22%) of cases. SNODs were involved in 76 (68%) of approaches. Consent was gained in 45 (41%) of families approached. Reasons for non consent were varied; surgery to the body was highest at 18%. The data has shown that the neurological testing rate, approach rate, SNOD involvement and the consent rate varied from 0% to 100% across the centres. <h3>Conclusion</h3> The data shows wide variation in unit processes, understanding the reasons for this variation is important in achieving potential for OD. Only 16 (6%) of the SNOD team have a paediatric qualification with 5 (31%) covering a PICU. Training SNODs in PICU processes plays a key role in unit relationships with OD teams. Demands on SNODs time with priority in areas with greater potential may reduce visibility in PICUs, potentially impacting on unit relationships. Overall data shows SNOD involvement in approach improves consent, this trend is replicated here. More research in consent for paediatrics is required to incorporate the specific needs of families in the context of these discussions. In high performing units there is a best practice culture with open team discussion regarding OD being a regular event. The benefits of embracing differences in practice, along with bespoke strategies to ensure OD is considered as a usual part of end of life care in paediatrics will be far reaching.
The physician's ethical obligation to take care of patients in times of plague
Journal: JAMA (1988)

<h3>In Reply.</h3> —I applaud Dr Clark's decision to continue to treat patients infected with the human immunodeficiency virus (HIV) and I am heartened by his statement that he considers treating patients with AIDS an obligation of a physician. That was precisely the point of my editorial. I believe that the singular duty incumbent on anyone who takes up the call of medicine is to care for patients, and that caring also encompasses those involved in teaching and research. The distinguishing feature of the medical profession as opposed to all other fields of endeavor is the absolute dedication to those in need of medical care. The essence of being a physician is the healing of the sick; any other activity is extraneous to that mission. Even if the risk of acquiring HIV from contact with patients infected with the virus was substantial, physicians would still incur the duty of treating those
Santa Maria!
Authors: L. V. Gould
Journal: JAMA (1977)

<h3>To the Editor.—</h3> A ship of the dimension given for the<i>Santa Maria</i>(236:1544, 1976) could be built and sailed, but it is extremely unlikely that the mainmast was anything like twice the length of the hull. By the mid-19th century, tall ships were relatively as well as absolutely taller than in Columbus' days, but a ship with a height to length ratio of 2:1 was impractical. To use a mast over 61 m (200 ft) in length would mean using a large hull. To illustrate my point, let me refer to the case of the<i>Great Republic</i>, designed and built by Donald McKay with such a mast. More than three centuries of progress in shipbuilding technique permitted her mainmast to be made in overlapping sections, of these dimensions<sup>1</sup>: This rig was after the design of Capt R. B. Forbes. However, the<i>Great Republic</i>did not sail with these