tbuckley/cabot-search huggingface dataset:
Impact of vaccination on postacute sequelae of SARS CoV-2 infection in patients with rheumatic diseases
Authors: Naomi J Patel, Claire Cook, Kathleen Vanni, Xiaoqing Fu, Xiaosong Wang, Yumeko Kawano, Grace Qian, Buuthien Hang, Shruthi Srivatsan, Emily P Banasiak, Emily Kowalski, Katarina Bade, Yuqing Zhang, Jeffrey A Sparks, Zachary S. Wallace
Journal: Annals of the Rheumatic Diseases (2022)

Vaccination decreases the risk of severe COVID-19 but its impact on postacute sequelae of COVID-19 (PASC) is unclear among patients with systemic autoimmune rheumatic diseases (SARDs) who may have blunted vaccine immunogenicity and be vulnerable to PASC.
T Cell Receptor Repertoire Profiling Reveals Breadth of Cellular Responses Against Sars-Cov-2 after Natural Infection and Vaccination in Allogeneic Hematopoietic Stem Cell Transplant Recipients
Authors: Anne-Claire Mamez, Amandine Pradier, Caroline Stephan, Federica Giannotti, Stavroula Masouridi-Levrat, Sarah Morin, Dionysios Neofytos, Diem-Lan Vu, Astrid Melotti, Isabelle Arm-Vernez, Christiane S. Eberhardt, Jerome Tamburini, Laurent Kaiser, Yves Chalandon, Federico Simonetta
Journal: Blood (2022)
A Novel BTK Inhibitor Induces Cells Death and Enhances the Efficacies of Venetoclax in Acute Myeloid Leukemia Cells
Authors: Nicole K Schmalbach, Omar S Al-Odat, Weam Elbezanti, Gabriella Yao, Daniel A Guirguis, Krishne Gowda, Shantu G Amin, Tulin Budak-Alpdogan, Subash C Jonnalagadda, Manoj Kumar Pandey
Journal: Blood (2022)
Efficacy and Safety of Viral Vector Based Gene Therapy in Patients with Hemophilia a: A Systematic Review
Authors: Wajeeha Aiman, Syeda Hafsa Kazmi, Memoona Saeed, Muhammad Imran Khan, Zainab Omar, Muhammad Suleman, Taimoor Jamil, Mahak Khadija Bhatti, Sigmone Khalid Butt, Hina Zubair, A. Supraja, Maha Zafar, Yusra Arooj, Muhammad Ashar Ali
Journal: Blood (2022)
Patient-Reported-Outcomes and Safety of Autologous Stem Cell Transplantation in Multiple Sclerosis: A Single Center Experience with the "Mexican Method" in 1300 Persons
Authors: Juan Carlos Olivares-Gazca, Daniela Sánchez-Bonilla, José Antonio Fernández-Gutiérrez, Oscar A. Reyes-Cisneros, Moisés Manuel Gallardo-Pérez, Guillermo José Ruiz-Delgado, Guillermo José Ruiz-Argüelles
Journal: Blood (2022)
A Patient-Centered Communication Tool for Older Patients with Acute Myeloid Leukemia, Their Caregivers, and Oncologists: A Single Arm Pilot Study
Authors: Marissa Locastro, Chandrika Sanapala, Ying Wang, Marielle Jensen-Battaglia, Marsha Wittink, Sally Norton, Heidi Klepin, Daniel R. Richardson, Jason H. Mendler, Jane L. Liesveld, Eric J. Huselton, Kristen M. O'Dwyer, Ashley-Marie Cortes, Chrystina Rodriguez, Kah Poh (melissa) Loh
Journal: Blood (2022)
Comprehensive Analysis of Mesenchymal Cells from Myeloproliferative Neoplasm (MPN) Patients Reveals the Role of <i>HOXB7</i> in Myelofibrosis Induction
Authors: Saravanan Ganesan, Sarah Awan-Toor, Fabien Guidez, Nabih Maslah, Celine Aoun, Panhong Gou, Chloe Guiguen, Juliette Soret, Odonchimeg Ravdan, Valeria Bisio, Nicolas Dulphy, Marie-Hélène Schlageter, Michele Souyri, Stephane Giraudier, Jean-Jacques Kiladjian, Christine Chomienne, Bruno Cassinat
Journal: Blood (2022)
A Real World Experience of Combined Treatment with Romidepsin and Azacitidine in Patients with Peripheral T-Cell Lymphoma - a Bridge to Transplant and an Effective Salvage for the Unfit
Authors: Matko Kalac, Salvia Jain, Constantine S. Tam, Mendel Goldfinger, Zhengrui Xiao, Francesca Montanari, Bryan D. Huber, Jennifer A. Kanakry, Owen A. O'Connor, Enrica Marchi
Journal: Blood (2022)
Single-Cell RNA-Sequencing of 245 Tumor Samples from Patients with MGUS and Smoldering Multiple Myeloma Reveals Novel Insights into Malignant Plasma Cell Biology
Authors: Junko Tsuji, Elizabeth D. Lightbody, Romanos Sklavenitis-Pistofidis, Michael P. Agius, Mahshid Rahmat, Hadley Barr, Yoshinobu Konishi, Ankit K. Dutta, Nang Kham Su, Cody J. Boehner, Danielle T. Firer, Ting Wu, Michelle P. Aranha, Laura Hevenor, Erica Horowitz, Jacqueline Perry, François Aguet, Nicholas J. Haradhvala, Rebecca Boiarsky, Gad Getz, Irene Ghobrial
Journal: Blood (2022)
Escape from Type II JAK2 Inhibition in MPN Depends on AXL/MAPK Activation and Is Targetable
Authors: Tamara Codilupi, Jakub Szybinski, Sime Brkic, Simona Stivala, Julie Yang, Nilabh Ghosh, Katarzyna Buczak, Jakob Passweg, Anne Angelillo-Scherrer, Stefan Dirnhofer, Ross L. Levine, Richard Koche, Sara C. Meyer
Journal: Blood (2022)
Maintenance Therapy Cessation for Sustained MRD Negative Multiple Myeloma Patients
Authors: Neha Korde, Benjamin Diamond, Miranda Burge, Hani Hassoun, Heather Landau, Malin Hultcrantz, Sham Mailankody, Kylee H Maclachlan, Urvi A Shah, Andriy Derkach, Saad Usmani, Ola Landgren, Alexander Lesokhin
Journal: Blood (2022)
Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis
Authors: Jessica Roelands, Manon van der Ploeg, Marieke E Ijsselsteijn, Hao Dang, Jurjen J Boonstra, James C H Hardwick, Lukas J A C Hawinkels, Hans Morreau, Noel F C C de Miranda
Journal: Gut (2022)

Objective Biological insights into the stepwise development and progression of colorectal cancer (CRC) are imperative to develop tailored approaches for early detection and optimal clinical management of this disease. Here, we aimed to dissect the transcriptional and immunologic alterations that accompany malignant transformation in CRC and to identify clinically relevant biomarkers through spatial profiling of pT1 CRC samples. Design We employed digital spatial profiling (GeoMx) on eight pT1 CRCs to study gene expression in the epithelial and stromal segments across regions of distinct histology, including normal mucosa, low-grade and high-grade dysplasia and cancer. Consecutive histology sections were profiled by imaging mass cytometry to reveal immune contextures. Finally, publicly available single-cell RNA-sequencing data was analysed to determine the cellular origin of relevant transcripts. Results Comparison of gene expression between regions within pT1 CRC samples identified differentially expressed genes in the epithelium (n=1394 genes) and the stromal segments (n=1145 genes) across distinct histologies. Pathway analysis identified an early onset of inflammatory responses during malignant transformation, typified by upregulation of gene signatures such as innate immune sensing. We detected increased infiltration of myeloid cells and a shift in macrophage populations from pro-inflammatory HLA-DR + CD204 − macrophages to HLA-DR − CD204 + immune-suppressive subsets from normal tissue through dysplasia to cancer, accompanied by the upregulation of the CD47/SIRPα ‘don’t eat me signal’. Conclusion Spatial profiling revealed the molecular and immunological landscape of CRC tumourigenesis at early disease stage. We identified biomarkers with strong association with disease progression as well as targetable immune processes that are exploitable in a clinical setting.
Dose of IV Busulfan in Reduced Toxicity Conditioning Regimen for Older and/or Frail Patients with AML or MDS
Authors: Raynier Devillier, Edouard Forcade, Jacques-Olivier Bay, Anne Huynh, Anna Berceanu, Régis Peffault de Latour, Claude-Eric Bulabois, Mohamad Mohty, Michael Loschi, Emmanuelle Tavernier, Micha Srour, Patrice Chevallier, Amandine Charbonnier, Aline Schmidt, Didier Blaise
Journal: Blood (2022)
High Efficacy of the PARP Inhibitor Olaparib Combined with High-Dose Chemotherapy and Autologous Stem-Cell Transplant for Refractory Lymphomas
Authors: Yago Nieto, Benigno C Valdez, Peter F Thall, Jeremy L. Ramdial, Samer A Srour, Chitra Hosing, Neeraj Saini, Amin M Alousi, Muzaffar H Qazilbash, Uday R Popat, Alison Gulbis, Terri Lynn Shigle, Roland Bassett, Maria Guillermo-Pacheco, Celina Ledesma, Paolo Strati, Sairah Ahmed, Raphael Steiner, Jason Westin, Ranjit Nair, Swaminathan P. Iyer, Richard E Champlin, Elizabeth J Shpall, Borje S Andersson
Journal: Blood (2022)
Phase I/II Clinical Trials of Donor-Derived Purified Regulatory T Cells for the Treatment of Steroid-Refractory Chronic Graft Versus Host Disease
Authors: Maria VD Soares, Virginia Escamilla Gomez, Rita I Azevedo, Paulo N.G. Pereira, Teresa Caballero Velázquez, Clara B. Garcia-Calderón, Kukatharmini Tharmaratnam, Inês A Cabral, Ana C Ribeiro, Laura Mendes, Clara Juncal, Susana Roncon, Ana Teresa Pais, Ana C Alho, Alfonso Rodriguez Gil, Eduardo L Espada, Anabela Rodrigues, Ana Garção, Marie-Laure Yaspo, Hans-Jörg Warnatz, Hans Lehrach, Nuno L. Barbosa-Morais, Ana Miguel Quintas, Paulo Palmela, Cecilia Caldas, Rosa Ferreira, Luis Leite, Carlos Martins, Fernanda Lourenço, Raúl Moreno, João Raposo, Fernando Campilho, Christopher Paul Cheyne, Marta Garcia-Fiñana, António Campos, Frédéric Baron, Mario Arpinati, Matthias Edinger, Jerome Ritz, Carlos Pinho Vaz, Jose A. Perez-Simon, Joao F Lacerda
Journal: Blood (2022)
Dual Targeting of MDM2 and BCL2/Bclxl Demonstrates Potent Synergistic Activity in High-Risk Adult Acute Lymphoblastic Leukemia
Authors: Hayden L Bell, Mankaran Singh, Helen J Blair, Olaf Heidenreich, Frederik W. van Delft, Anthony V. Moorman, John Lunec, Julie Irving
Journal: Blood (2022)
A Phase 2 Study of Pembrolizumab (MK-3475) after Autologous Stem Cell Transplantation in Patients with T-Cell Non-Hodgkin Lymphoma
Authors: Mwanasha H. Merrill, Parastoo B. Dahi, Robert A. Redd, Mikaela M. McDonough, Yi-Bin Chen, Ann S. LaCasce, David C. Fisher, Alex F. Herrera, Caron A. Jacobson, Austin I. Kim, Reid W Merryman, Oreofe O. Odejide, Samuel Ng, Yago Nieto, Craig S. Sauter, Gunjan L. Shah, Jasmine Zain, Philippe Armand, Eric D Jacobsen
Journal: Blood (2022)
Replacing Procarbazine with Dacarbazine in Escalated Beacopp Dramatically Reduces the Post Treatment Haematopoietic Stem and Progenitor Cell Mutational Burden in Hodgkin Lymphoma Patients with No Apparent Loss of Clinical Efficacy
Authors: Anna Santarsieri, Emily Mitchell, Katherine Sturgess, Pauline Brice, Tobias F. Menne, Wendy Osborne, Thomas Creasey, Kirit M. Ardeshna, Sarah Behan, Kaljit Bhuller, Stephen Booth, Nikesh D. Chavda, Graham P. Collins, Dominic J. Culligan, Kate Cwynarski, Andrew Davies, Abigail Downing, David Dutton, Michelle Furtado, Eve Gallop-Evans, Andrew Hodson, David Hopkins, Hannah Hsu, Sunil Iyengar, Stephen G. Jones, Kim M. Linton, Oliver C. Lomas, Nicolas Martinez-Calle, Abhinav Mathur, Pamela McKay, Sateesh K. Nagumantry, Deirdre O'Mahony, Elizabeth H. Phillips, Neil Phillips, John F. Rudge, Nimish K. Shah, Gwyneth Stafford, Alex Sternberg, Rachel Trickey, Benjamin J. Uttenthal, Natasha Wetherall, Andrew K. McMillan, Michael Stratton, Elisa Laurenti, Peter J. Campbell, George A. Follows
Journal: Blood (2022)
Plasma Metabolomic Profiles Are Imbalanced in Adults Thalassemia Patients with Malnutrition and That Imbalance Is Alleviated By Oral Nutritional Supplements: A Prospective Randomized Controlled Trial
Authors: Rattana Weerasathain, Pokpong Piriyakhuntorn, Adisak Tantiworawit, Supawan Buranapin, Chanisa Thonusin, Piangrawee Niprapan, Nonthakorn Hantrakun, Teerachat Punnachet, Thanawat Rattanathammethee, Sasinee Hantrakool, Chatree Chai-Adisaksopha, Ekarat Rattarittamrong, Lalita Norasetthada, Nipon Chattipakorn, Siriporn C. Chattipakorn
Journal: Blood (2022)
Subcutaneous Mosunetuzumab Is Active with a Manageable Safety Profile in Patients (pts) with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphomas (B-NHLs): Updated Results from a Phase I/II Study
Authors: Elizabeth L. Budde, Nancy L. Bartlett, Pratyush Giri, Stephen J. Schuster, Sarit Assouline, Sung-Soo Yoon, Keith Fay, Matthew J. Matasar, Norma C. Gutierrez, Paula Marlton, Martin Dreyling, Dok Hyun Yoon, Georg Hess, John Radford, Volker Wiebking, Shen Yin, Eva Cybulski, David C. Turner, Huang Huang, Mingzhu Zhou, Elicia Penuel, Michael C. Wei, Laurie H. Sehn
Journal: Blood (2022)
BCR::ABL1-Positive Acute Lymphoblastic Leukemia: Different Clinical Behavior and Relevance of Prognostic Features in Typical ALL and in CML-like Disease
Authors: Jan Zuna, Lenka Hovorkova, Justina Krotka, Amelie Koehrmann, Michela Bardini, Lucie Winkowska, Eva Fronkova, Julia Alten, Rolf Koehler, Cornelia Eckert, Lisa Brizzolara, Jan Stuchly, Martin Zimmermann, Paola De Lorenzo, Maria Grazia Valsecchi, Valentino Conter, Jan Stary, Martin Schrappe, Andrea Biondi, Jan Trka, Marketa Zaliova, Giovanni Cazzaniga, Gunnar Cario
Journal: Blood (2022)
High Immunoproteasome Expression As Indicator for Sensitivity to Bortezomib-Containing Chemotherapy in Newly Diagnosed, Standard and Intermediate Risk, T-Cell Acute Lymphoblastic Leukemia Patients from Children's Oncology Group Trial AALL1231
Authors: Margot S.F. Roeten, Johan van Meerloo, Zinia Kwidama, Gaye Jenkins, Suzanne N. van Dijk, David T. Teachey, Meenakshi Devidas, Mignon L. Loh, Gertjan J.L. Kaspers, Sonja Zweegman, Gerrit Jansen, Jacqueline Cloos, Terzah M. Horton
Journal: Blood (2022)
Effect of Two Conditionings on Relapse in Myelodysplastic Syndrome and Secondary Acute Myeloid Leukemia Undergoing Allogeneic Hematopoietic Cell Transplantation
Authors: Li Xuan, Min Dai, Erlie Jiang, Yu Wang, Fen Huang, Zhiping Fan, Na Xu, Danian Nie, Xinquan Liang, Hong Chen, Jieyu Ye, Pengcheng Shi, Hui Liu, Hua Jin, Ren Lin, Chenhua Yan, Yu Zhang, Jing Sun, Mingzhe Han, Qifa Liu
Journal: Blood (2022)
Pembrolizumab and Chemotherapy in Newly-Diagnosed, Early Unfavorable or Advanced Stage Classic Hodgkin Lymphoma: The Phase 2 Keynote-C11 Study
Authors: Ranjana H. Advani, Abraham Avigdor, Anna Sureda, David Lavie, Stefan Hohaus, Jan M. Zaucha, Vu Minh Hua, Vittorio Ruggero Zilioli, Raimundo Gazitua, Muhit Özcan, Amos Odeleye-Ajakaye, Uzor C. Ogbu, Akash Nahar, Jane N. Winter
Journal: Blood (2022)
Pharmacologic Inhibition of DYRK1A Results in Hyperactivation and Hyperphosphorylation of MYC and ERK Rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition
Authors: V. S. S. Abhinav Ayyadevara, Gerald Wertheim, John Chukinas, Joseph Patrick Loftus, Sung June Lee, Anil Kumar, Rahul S. Bhansali, Srividya Swaminathan, Thierry Besson, Junwei Shi, John D. Crispino, Sarah K Tasian, Martin P. Carroll, Christian Hurtz
Journal: Blood (2022)
A Randomized Phase II Trial Comparing BeEAM with BEAM As Conditioning Regimen for Autologous Stem Cell Transplantation in Lymphoma Patients
Authors: Felix Keil, Antonia Maria Susanne Müller, Andrea Berghold, Veronika Buxhofer-Ausch, Judith Schuster, Regina Riedl, Corinne Vorburger, Alexandra Boehm, Michael Panny, Thomas Noesslinger, Richard Greil, Panagiotis Samaras, Thomas Pabst
Journal: Blood (2022)
High-Grade B-Cell Lymphoma, Not Otherwise Specified (HGBL, NOS): Central Nervous System (CNS) Involvement, Prophylaxis, and Recurrence Risk in a Multi-Institutional Series
Authors: Narendranath Epperla, Adam Zayac, Daniel J. Landsburg, Mitchell Hughes, Allison M. Bock, Grzegorz S. Nowakowski, Emily C. Ayers, Mark Girton, Marie Hu, Amy Beckman, Shaoying Li, L. Jeffrey Medeiros, Julie E. Chang, Adam Stepanovic, Habibe Kurt, Jose Sandoval-Sus, M. Ali Ansari-Lari, Shalin K. Kothari, Anna Kress, Mina L Xu, Pallawi Torka, Suchitra Sundaram, Stephen D Smith, Kikkeri N Naresh, Yasmin Karimi, David A. Bond, Umar Farooq, Mahak Saad, Andrew Matthew Evens, Karan Pandya, Seema G Naik, Manali Kamdar, Bradley M. Haverkos, Reem Karmali, Timothy S Oh, Julie M. Vose, Heather Nutsch, Paul Rubinstein, Amina Chaudhry, Adam J. Olszewski
Journal: Blood (2022)
The Dramatic Impact of the War on Access to Treatment for Lymphoma Patients. a Report from the Ukrainian Lymphoma Registry
Authors: Yana Stepanishyna, Iryna Kriachok, Nazar Shokun, Nataliia Shapovalenko, Anisiia Luchkiv, Tetiana Skrypets, Martina Manni, Massimo Federico
Journal: Blood (2022)
A Simplified Patient Care Strategy to Decrease Early Deaths in Acute Promyelocytic Leukemia (APL): Results of the ECOG-ACRIN EA9131 Trial
Authors: Anand P. Jillella, Sandra J. Lee, Jessica K. Altman, Selina M. Luger, Martin S. Tallman, James M. Foran, Lisa Y. Law, Locke J. Bryan, Abdallah Abou Zahr, Kebede Begna, Alexander Perl, Joseph Vadakara, Federico Sanchez, Raymond C. Bergan, Michael J. Fisch, Ruth C. Carlos, Lynne I. Wagner, Mark R. Litzow, Vamsi K. Kota
Journal: Blood (2022)
Genetic and Epigenetic <i>Cis</i>-Regulatory Disruptions Impacting the Canonical Wnt Signaling Repressor <i>TLE1</i> Gene Promote Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia
Authors: Brennan P. Bergeron, Jonathan D. Diedrich, Yang Zhang, Kelly R. Barnett, Qian Dong, Daniel Ferguson, Robert J Autry, Wenjian Yang, Baranda S Hansen, Colton A Smith, Kristine R. Crews, Yiping Fan, Ching-Hon Pui, Shondra Miller, Mary V. Relling, Jun J. Yang, Chunliang Li, William E. Evans, Daniel Savic
Journal: Blood (2022)
Early Breakthrough T Cell Proliferation Despite CNI/MTX Prophylaxis Is a Harbinger of Acute Gvhd (AGVHD) and Is Controlled By Abatacept: Mechanism of Success of the ABA2 Agvhd Prevention Trial
Authors: Alexandre Albanese, Alal Eran, Yvonne Suessmuth, Kayla Betz, Brandi Bratrude, Paula Keskula, Lorenzo Cagnin, Amelia Langston, Muna Qayed, John T. Horan, Bruce R. Blazar, Benjamin Watkins, Leslie S. Kean
Journal: Blood (2022)
<i>BCL6-Mediated Escape from Negative Selection Enables RAS-Driven B-Cell Transformation</i>
Authors: Lai N. Chan, Christian Hurtz, Mark E. Robinson, Etienne Leveille, Huimin Geng, Rebecca Caeser, Liang Xu, Kohei Kume, Gang Xiao, Markus Müschen
Journal: Blood (2022)
Progression Risk and Long-Term Survival Trends of 915 Patients with Asymptomatic IgM Monoclonal Gammopathy
Authors: David F. Moreno, Cristina Jiménez, Fernando Escalante Barrigón, Elham Askari, Mario Arnao, Ángela Heredia, Magdalena Alcalá, Arancha Bermúdez, Ana Saus Carreres, Maria Casanova, Luis Palomera, Cristina Motllo, Ricarda Belen Garcia Sanchez, Ramón García-Sanz, Carlos Fernández De Larrea
Journal: Blood (2022)
Longitudinal, Real-World Data Reveal Treatment Effectiveness in Idiopathic Multicentric Castleman Disease and Support Current Treatment Guidelines
Authors: Sheila K Pierson, Mateo Sarmiento Bustamante, Joshua D Brandstadter, Daisy Alapat, Adam Bagg, Mary Jo Lechowicz, Gordan Srkalovic, Megan S. Lim, Frits van Rhee, David C Fajgenbaum
Journal: Blood (2022)
Nivolumab and AVD in Early-Stage Unfavorable Hodgkin Lymphoma: Follow-up Analysis of the Randomized GHSG Phase II Nivahl Trial
Authors: Paul J Bröckelmann, Ina Bühnen, Julia Meissner, Karolin Trautmann-Grill, Peter Herhaus, Teresa V Halbsguth, Valdete Schaub, Andrea Kerkhoff, Stephan Mathas, Matthias Bormann, Andreas Dickhut, Helen Kaul, Michael Fuchs, Carsten Kobe, Christian Baues, Peter Borchmann, Andreas Engert, Bastian von Tresckow
Journal: Blood (2022)
Simultaneous Inhibition of SIRT3 and Cholesterol Homeostasis Targets AML Stem Cells By Perturbing Fatty Acid β-Oxidation and Inducing Lipotoxicity
Authors: Cristiana O'Brien, Tianyi Ling, Jacob Berman, Rachel Culp-Hill, Julie A. Reisz, Vincent Rondeau, Soheil Jahangiri, Jonathan St-Germain, Vinitha Macwan, Audrey Astori, Andy G.X. Zeng, Jun Young Hong, Meng Li, Min Yang, Sadhan Jana, John E. Dick, Hening Lin, Ari Melnick, Anastasia N Tikhonova, Andrea Arruda, Mark D. Minden, Brian Raught, Angelo D'Alessandro, Courtney L Jones
Journal: Blood (2022)
Prevalence of MGUS Is High in the Istopmm Study but the Prevalence of IgA MGUS Does Not Increase with Age in the Way Other Immunoglobulin Subtypes Do
Authors: Thorvardur Jon Love, Sæmundur Rögnvaldsson, Sigrun Thorsteinsdottir, Thor Aspelund, Elin Ruth Reed, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni Agnar Agnarsson, Margret Sigurdardottir, Ingunn Thorsteinsdottir, Signy Vala Sveinsdottir, Isleifur Olafsson, Fridbjorn Sigurdsson, Asdis Rosa Thordardottir, Elias Eythorsson, Asbjorn Jonsson, Runolfur Palsson, Olafur Skuli Indridason, Gauti Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Ingigerdur Solveig Sverrisdottir, Hlif Steingrimsdottir, Thorir Einarsson Long, Malin Hultcrantz, Brian G.M. Durie, Stephen Harding, Ola Landgren, Sigurdur Y Kristinsson
Journal: Blood (2022)
Myeloid Neoplasms with <i>MYC</i>-Positive Double Minutes, a Specific Subgroup?
Authors: Isolde Summerer, Wencke Walter, Manja Meggendorfer, Torsten Haferlach, Stephan Hutter, Niroshan Nadarajah, Constance Baer, Anna Stengel, Wolfgang Kern, Claudia Haferlach
Journal: Blood (2022)
Tazemetostat in Combination with Lenalidomide and Rituximab in Patients with Relapsed/Refractory Follicular Lymphoma: Phase 1b Results of Symphony-1
Authors: Connie Lee Batlevi, Gilles Salles, Steven I. Park, Tycel J. Phillips, Jennifer E. Amengual, David Andorsky, Philip Campbell, Pamela McKay, John P. Leonard, Manu Sondhi, Yingxue Chen, Pamela L. Slatcher, Richard Lin, Attila Szanto, Sara Abbadi, Franck Morschhauser
Journal: Blood (2022)
High Dose Methotrexate Does Not Reduce the Risk of CNS Relapse in Children and Young Adults with Acute Lymphoblastic Leukaemia and Lymphoblastic Lymphoma. Results of the Randomised Phase III Study UKALL 2011
Authors: Amy A. Kirkwood, Nicholas Goulden, John Moppett, Sujith Samarasinghe, Jon Mee, Rachael Hough, Pamela R. Kearns, Sarah Lawson, Clare J. Rowntree, Ajay Vora
Journal: Blood (2022)
A Novel IL2Rα-/- Model for CAR-T Toxicity in Acute Lymphoblastic Leukemia Recapitulates Cytokine Release Syndrome and Neutropenia
Authors: Payal Goala, Hiroshi Kotani, Zhang Yongliang, Kayla M. Reid, Justin C. Boucher, Constanza Savid-Frontera, Sae Bom Lee, Nolan Beatty, Michael D. Jain, Marco L. Davila
Journal: Blood (2022)
High Fatality CBFA2T3-GLIS2 Pediatric Acute Megakaryoblastic Leukemia Is Sensitive to BCL-XL Inhibition
Authors: Verena Gress, Mathieu Roussy, Sophie Cardin, Luc Boulianne, Furat Fatima, Louise Laramée, Emma R. Cheetham, Alexandre Rouette, Nehme Hachem, Véronique Lisi, Azer Farah, Melanie Bilodeau, Frederic Barabe, Vincent-Philippe Lavallée, Brian T. Wilhelm, Sonia Cellot
Journal: Blood (2022)
Novel Sirpα-Fc Fusion Protein IMM01 Exhibits Dual Anti-Tumor Activities By Targeting CD47/Sirpα Signal Pathway
Authors: Jifeng Yu, Song Li, Dianze Chen, Dandan Liu, Huiqin Guo, Chunmei Yang, Wei Zhang, Li Zhang, Gui Zhao, Xiaoping Tu, Liang Peng, Sijin Liu, Xing Bai, Yongping Song, Zhongxing Jiang, Ruliang Zhang, Wenzhi Tian
Journal: Blood (2022)
Additional Mutational Events at Diagnosis of CML Confer Inferior Failure-Free Survival and Molecular Response for Patients Treated with Frontline Imatinib but Not for Patients Treated with Frontline Second-Generation Tyrosine Kinase Inhibitors
Authors: Naranie Shanmuganathan, David T Yeung, Carol Wadham, Nur Hezrin Shahrin, Adelina Fernandes, Jinghua Feng, Verity A Saunders, Ming Lin, Rosalie Kenyon, Rob King, Paul Wang, David M Ross, Andreas W Schreiber, Timothy Hughes, Susan Branford
Journal: Blood (2022)
Outcomes of Non-Myeloablative HLA-Haploidentical Bone Marrow Transplant with Thiotepa and Post-Transplant Cyclophosphamide in Children and Adults with Sickle Cell Disease, a Phase II Trial: Vanderbilt Global Haploidentical Transplant Learning Collaborative (VGC2)
Authors: Adetola A. Kassim, Karina Wilkerson, Josu de la Fuente, Adriana Seber, Roseane V Gouveia, Carmem Bonfim, Belinda Pinto Simões, Erfan Nur, Biljana N. Horn, Michael Eckrich, Rabi Hanna, Nathalie Dhedin, Fahed Almhareb, Mahmoud Aljurf, Hemalatha G. Rangarajan, Katie S. Gatwood, James P Connelly, Mohsen Alzahrani, Ali Alahmari, Mark Rodeghier, Michael R. DeBaun
Journal: Blood (2022)