tbuckley/cabot-search huggingface dataset:
Response
Authors: D. T. JANERICH, W. D. THOMPSON, G. P. MINEAU
Journal: JNCI Journal of the National Cancer Institute (1995)

contrast, the pregnancy estrogen hypothesis, that Janerich et al. ( 7) dismiss, provides a plausible explanation for the past association of breast cancer risk with socioeconomic class.Higher levels of pregnancy estrogens tend to be associated with higher birth size, which has been linked to breast cancer risk (9) and has also been positively associated with socioeconomic status (JO).
Pharyngeal gonorrhea
Authors: A. W. Tice
Journal: JAMA (1981)

Cultures of genital sites and pharynx were obtained from 903 prostitutes and 102 active-duty men at Clark AFB, Republic of the Philippines, during the first quarter of 1981. Slightly more than 2.2% positive pharyngeal cultures in the women and 6% in the men were noted. Both penicillinsensitive and penicillinase-producing<i>Neisseria gonorrhoeae</i>(PPNG) were recovered. Treatment and follow-up of the pharyngeal infections were available only for the men seen at the Clark Public Health Clinic. These men responded to penicillin G procaine for penicillin-sensitive<i>N gonorrhoeae</i>and to spectinomycin hydrochloride for PPNG. A retrospective review of cases of male gonococcal urethritis seen in 1980 in the Clark Public Health Clinic revealed 46 cases of probable oral-to-genital transfer of<i>N gonorrhoeae</i>among more than 2,600 cases of gonococcal urethritis. Of these 46, fifteen were PPNG. The importance of the pharynx as a source of infection is thus substantiated. (<i>JAMA</i>1981;246:2717-2719)
Coeur d'Alene
Authors: Richard B. Weinberg
Journal: Annals of Internal Medicine (2016)

On Being a Doctor6 December 2016Coeur d'AleneRichard B. Weinberg, MDRichard B. Weinberg, MDFrom Wake Forest School of Medicine, Winston-Salem, North Carolina.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M16-0258 Audio Reading - “Coeur d'Alene” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Coeur d'Alene," by R.B. Weinberg. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Despite the fact that Colossus, our new electronic health record program, had a confusing interface of unintuitive icons, dead-end click paths, and unwanted functions that could only have been designed by a cabal of computer geeks and business administrators, I did my best to adapt it to the needs of my practice. But I immediately noted a distressing problem: Using Colossus to enter even the simplest note required more of my time—a lot more. Soon I was spending as much time tending to my charts as I was talking to my patients. And Colossus was monitoring my every click, the ... Author, Article, and Disclosure InformationAffiliations: From Wake Forest School of Medicine, Winston-Salem, North Carolina.Corresponding Author: Richard B. Weinberg, MD, Wake Forest School of Medicine, One Medical Center Boulevard, Winston-Salem, NC 27157; e-mail, [email protected]edu. PreviousarticleNextarticle Advertisement Audio Reading - “Coeur d'Alene” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Coeur d'Alene," by R.B. Weinberg. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics Cited byAllocation of Physician Time in Ambulatory PracticeDavid P. Serota, MD 6 December 2016Volume 165, Issue 11Page: 822-823KeywordsChartsChildrenComputersDiarrheaMilkPathogensPatient advocacySerologySoftware toolsStroke ePublished: 6 December 2016 Issue Published: 6 December 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Carcinoid syndrome.
Authors: E Galanis, L K Kvols, J Rubin
Journal: Journal of Clinical Oncology (1998)

Article Tools Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1998.16.2.796 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 9469372 Carcinoid syndrome. E GalanisxE GalanisSearch for articles by this author , L K KvolsxL K KvolsSearch for articles by this author , J RubinxJ RubinSearch for articles by this author Show More Mayo Clinic, Rochester, MN, USA. https://doi.org/10.1200/JCO.1998.16.2.796 First Page PDF © 1998 by American Society of Clinical Oncology
The Effect of Digitalis on the Cardiac Output of the Normal Heart at Rest and During Exercise.
Authors: T. Rodman
Journal: Annals of Internal Medicine (1961)

s1 May 1961The Effect of Digitalis on the Cardiac Output of the Normal Heart at Rest and During Exercise.T. Rodman, M.D., (Assoc.), C. A. Gorczyca, M.D., B. H. Pastor, M.D., F.A.C.P.T. Rodman, M.D., (Assoc.)Search for more papers by this author, C. A. Gorczyca, M.D.Search for more papers by this author, B. H. Pastor, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-5-1039_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAlthough it is generally stated that digitalis reduces the cardiac output of the normal heart, the experimental basis for the statement is questionable. The available data are sparse and contradictory because, until recently, determinations of the cardiac output required catheterization of the pulmonary artery and application of the Fick principle, a technically difficult and time-consuming procedure which is not readily reproducible.A study was therefore undertaken utilizing a highly standardized dye dilution technic for the measurement of cardiac output. Sixteen normal young adult men were studied. The cardiac output, heart rate, stroke volume, minute ventilation, oxygen uptake, CO2production, and... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1961Volume 54, Issue 5Page: 1039-1040KeywordsCardiac outputCatheterizationExerciseHeartHeart rateOxygenPulmonary arteriesStrokeYoung adults ePublished: 1 December 2008 Issue Published: 1 May 1961 PDF downloadLoading ...
Editorial Board
Authors: P Coates, Olivier Devuyst, Tilman Drueke, Paris Ckd, Jürgen Floege, Aachen Glomerulonephritis, Agnes Fogo, T Alp Ikizler, Jai Radhakrishnan, York Kir, Germaine Wong, Pierre Ronco, Brad Rovin, Detlef Schlöndorff, New York, Qais Al-Awqati, Saulo Klahr, St Louis, Thomas Andreoli, Little Rock, Roscoe Robinson, Durham Nephrology, Christina Wyatt, Vic Hasselblad, Jacksonville Zhezhen, Joseph Kim, Yi-Ju Li, , Durham, Dorothea Nitsch, London Ramakrishnan, Anupam Agarwal, Hans Anders, Jonathan Barratt, David Basile, Francois Berthoux, Emmanuel Loire, São Burdmann, Daniel Paulo, Christos Toronto, Yi-Pu Paris, Erik Chen, Steven Christensen, New Coca, Terence York, London Cook, D Vivette, New Agati, Farhad York, John Danesh, Andrew Daugirdas, Ian Davenport, Marc De Boer, Vikas Antwerp, St Dharnidharka, Kent Louis, Zheng Doi, Adriana Dong, Kai-Uwe Oviedo, Berlin Eckardt, Eiam-Ong Somchai, Michael Emmett, Dallas Endre, Sydney Evan, Pieter Evenepoel, Sarah Leuven, Denver Faubel, Fernando Faul, Rochester Fervenza, Danilo Mineola, Alessia Homburg, Barry Miami, Winston-Salem Freedman, Isehara Masafumi Fukagawa, Vesna Garg, Rochester Garovic, Laguna Glassock, Glenda Niguel, David Gobe, New Goldfarb, Matthew York, Mark Griffin, Angeles Haas, John Haase, Cijiang He, Michelle Hladunewich, Thomas Hostetter, Chi-Yuan Cleveland, San Hsu, Tobias Francisco, Benjamin Huber, St Humphreys, Reiko Louis, Jula Tokyo, Dallas Inrig, Francisco Kirsten Johansen, Roberto Kamyar Kalantar-Zadeh, Iowa Kalil, Yashpal City, Chicago Kanwar, New Kaskel, Krzysztof York, York Kiryluk, Clayton Kitching, Matthias Kopp, Ann Kretzler, Christian Arbor, Christophe Bonn, Paris Legendre, Los Lemley, Adeera Angeles, Philip Levin, Hong Li, Christoph Kong, John Toronto, Rochester Lieske, Jiannong Little, Kathleen Liu, San Liu, Youhua Francisco, Zhi-Hong Liu, Nanjing Liu, Dallas Lu, Matthias Berlin, Johannes Mack, Peter Mann, Hamilton Margetts, New Glen Markowitz, Ziad York, Kunihiro Paris, Rajnish Matsushita, Timothy Mehrotra, Palo Meyer, Jeffrey Alto, St Miner, William Louis, Houston Mitch, Jeremiah Moeller, St Morrissey, Rosa Louis, São Moysés, Rama Paulo, Peter Duarte, David Nelson, Clayton Nikolic-Paterson, Klaus Charlottesville, Juan Oliver, York Charles O'neill, Atlanta Panzer, Mark Perazella, New Haven, Janos Peti-Peterdi, Los Angeles, Laura Plantinga, Atlanta Pollak, Didier Boston, Ambra Charlottesville, Susan Pozzi, Chicago Quaggin, Pia Maria, Milan Rastaldi, San Reeves, Heather Antonio, Jochen Reich, Giuseppe Reiser, Sharon Bergamo, Mariano Clayton, Mitchell Rodriguez, Michael Rosner, Robert Ross, Simone Safirstein, New Sanna-Cherchi, Antonio York, Kai Santoro, New Schmidt-Ott, Stephan York, Aarau Segerer, Sharma Kumar, La Jolla, Katalin Susztak, Tetsuhiro Tanaka, Tokyo Sydney, C Tang, Hong Kong, Ravi Thadhani, Joshua Boston, Jens Denver, Marcello Singapore, Frank Tonelli, Manjeri Van Der Sande, San Venkatachalam, Carsten Antonio, Joel Wagner, Ann Weinberg, Matthew Arbor, Donald Weir, Temple Wesson, Jack Westenfelder, Adam Wetzels, Myles Whaley-Connell, Keng-Thye Durham, Kwan-Dun Woo, Taiwan Wu, Yusuke Suzuki, Tokyo Zeisberg
Journal: Kidney International (2017)
Deaths of drug addicts in the United Kingdom 1967-81
Authors: H. Ghodse, M. Sheehan, C. Taylor, G. Edwards
Journal: BMJ (1985)

A search of the Home Office index of notified drug addicts identified 1499 deaths during 1967-81, of which 226 (15%) were of therapeutic addicts-that is, patients who had become addicted during medical treatment with a notifiable drug-and 1273 (85%) were of non-therapeutic addicts.The crude mortality fell from 23-5/1000/year for the period 1968-70 to 18 4/1000/year for 1978-80.Altogether 416 addicts aged under 50 at notification died after 1972, which was 16 times the number of deaths expected in a population with a similar age and sex composition.A more detailed examination of the cohorts of addicts notified each year showed little variation between them in the first two years of follow up.Nineteen addicts (16%) had died by 31 December of the year of their notification and 39 (3-3%) one year later.These figures may be an indication of the clinical course of addiction.Most deaths of non-therapeutic addicts in which a drug was implicated (939 cases (74%)) were due to medically prescribed drugs-barbiturates at first and later opiates such as dipipanone hydrochloride and dextromoramide.Heroin was implicated in only 65 (7%) of these deaths.The Home Office index is a valuable source for identifying drugs of abuse and serious problems of addiction.The fact that prescribed drugs are causing the death of so many addicts demands a response from the medical profession.
The geographic distribution of measles in the United States, 1980 through 1989
Authors: B. S. Hersh
Journal: JAMA (1992)

<h3>Objective.</h3> —To describe the geographic distribution of measles cases in the United States by county for the 10-year period from 1980 through 1989. <h3>Design.</h3> —Ecological analysis of national measles surveillance data. <h3>Methods.</h3> —Measles cases reported to the<i>Morbidity and Mortality Weekly Report</i>from 1980 through 1989 were analyzed. Data from the 1980 and 1990 US censuses were used to produce demographic profiles for each of the 3137 counties. Outcome variables examined included mean annual incidence and number of years reporting measles, with use of Spearman's rank correlation coefficients to examine the association between the demographic and the two outcome variables. <h3>Results.</h3> —A total of 56775 measles cases were reported during the decade. Of the nation's 3137 counties, 1690 (53.9%) did not report any cases; only 17 (0.5%) reported measles in all 10 years. Counties reporting measles more frequently during the decade had higher median populations, population densities, and percentage of black and Hispanic populations than those counties reporting less frequently. Population size, population density, and percentage of Hispanic population were associated with number of years reporting measles and mean annual measles incidence rate. Measles cases in counties reporting measles every year predominately occurred in unvaccinated preschoolers; cases in counties reporting less frequently predominately occurred in vaccinated school-aged children. <h3>Conclusions.</h3> —This analysis illustrates the focal nature of measles in the United States during the past decade. Most counties have not reported a single case of measles during the entire decade, and only 17 counties reported measles every year. Targeted strategies are needed to improve age-appropriate immunization levels among preschool-aged children living in large inner-city areas. (<i>JAMA</i>. 1992;267:1936-1941)
AB0132 Intra-articular glucocorticoid injections decrease the number of steroid hormone receptor positive cells in synovial tissue of patients with persistent knee arthritis
Authors: M.C. van der Goes, R.H. Straub, M.J. Wenting-Van Wijk, S. Capellino, J.W. Jacobs, Z.N. Jahangier, L. Rauch, J.W. Bijlsma, F.P. Lafeber
Journal: Annals of the Rheumatic Diseases (2013)

<h3>Objectives</h3> To explore changes in numbers of steroid hormone receptor positive cells in synovial tissue (ST) after intra-articular glucocorticoid injection, to correlate these changes to changes in clinical parameters, and to evaluate whether the number of steroid hormone receptor positive cells predicted the clinical response to the glucocorticoid injection. <h3>Methods</h3> Fourteen patients with persisting knee arthritis despite at least two previous injections in an outpatient setting received an intra-articular injection with glucocorticoids, followed by three days of admission with bed rest. Clinical efficacy was assessed at six and twelve weeks. ST biopsies were taken two weeks before and twelve weeks after injection. Presence of different cell types (T cells, macrophages, fibroblast-like synoviocytes) and numbers of glucocorticoid-, androgen-, and estrogen alpha and beta receptor positive cells were evaluated by histochemistry. <h3>Results</h3> Patients showed, despite previous failing, good clinical response to glucocorticoid injection with significant improvement in erythrocyte sedimentation rate, visual analogue scale (VAS) for pain, and joint disability score. Interestingly, the number of steroid hormone receptor positive cells decreased markedly (p&lt;0.05 for all four receptors). The decrease in estrogen receptor alpha positive cells correlated significantly with the improvement in VAS pain and joint disability score. The number of glucocorticoid-, androgen-, and estrogen alpha and beta receptor positive cells before injection did not predict the effect of this treatment. <h3>Conclusions</h3> Intra-articular glucocorticoid injections followed by bed rest for persisting arthritis are clinically effective and significantly decrease the number of steroid hormone receptor positive cells in ST. The relevance of the latter needs further study. <h3>Disclosure of Interest</h3> None Declared
Guidelines on the management of asthma. Statement by the British Thoracic Society, the Brit. Paediatric Association, the Research Unit of the Royal College of Physicians of London, the King's Fund Centre, the National Asthma Campaign, the Royal College of General Practitioners, the General Practitioners in Asthma Group, the Brit. Assoc. of Accident and Emergency Medicine, and the Brit. Paediatric Respiratory Group.
Journal: Thorax (1993)

group of respiratory and general physicians and general practitioners and modified after wide circulation and discussion within the British Thoracic Society.The guidelines were intended to be reviewed and revised after two years.Such
Extern Maternities v. Lying-In Hospitals
Journal: BMJ (1867)

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Error in Abstract
Journal: JAMA Network Open (2021)

Lauren A. Eberly, MD, MPH; Michael J. Kallan, MS; Howard M. Julien, MD, MPH, ML; Norrisa Haynes, MD, MPH; Sameed Ahmed M. Khatana, MD, MPH; Ashwin S. Nathan, MD; Christopher Snider, MPH; Neel P. Chokshi, MD, MBA; Nwamaka D. Eneanya, MD, MPH; Samuel U. Takvorian, MD, MS; Rebecca Anastos-Wallen, MD; Krisda Chaiyachati, MD, MPH, MS; Marietta Ambrose, MD, MPH, MSEd; Rupal O’Quinn, MD; Matthew Seigerman, MD; Lee R. Goldberg, MD, MPH; Damien Leri, MSEd, MPH; Katherine Choi, MD; Yevginiy Gitelman, MD; Daniel M. Kolansky, MD; Thomas P. Cappola, MD, ScM; Victor A. Ferrari, MD; C. William Hanson, MD; Mary Elizabeth Deleener, MBA, BSN, RN; Srinath Adusumalli, MD, MSc
Thousands of US Deaths From Stroke and Heart Disease Are Preventable
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pretreatment with delta-opioid receptor blockade attenuates the reduction of apoptosis associated with ischemic preconditioning or morphine-induced cardioprotection in rabbit ischemia/reperfusion model Shinji Okubo, Yujirou Tanabe, Nakaba Fujioka, Noboru Takehoski, Rakesh C. Kukreja. Kanzawa Medical University, Uchinada, Japan
Journal: Journal of the American College of Cardiology (2001)
Mitochondrial dysfunction in alcoholic patients as assessed by breath analysis
Authors: B Lauterburg
Journal: Hepatology (1993)

Mitochondria of patients with alcoholic liver disease are morphologically abnormal, and mitochondria isolated from animals exposed to ethanol exhibit functional deficiencies in vitro. Because the functional consequences of the morphological alterations and the relevance of in vitro observations to mitochondrial function in alcoholic subjects are not clear, we assessed mitochondrial function noninvasively with a breath test. Mitochondrial function was assessed by measuring the exhalation of 14CO2 after administration of 1 m̈Ci 2-keto[1-14C]isocaproic acid, the decarboxylation of which occurs in mitochondria. The results of the 2-keto[1-14C]isocaproic acid breath test in 17 alcoholic subjects were compared with the results in healthy controls and patients with nonalcoholic liver disease. The peak exhalation of 14CO2 and the fraction of the administered dose decarboxylated in 60 min were significantly lower in alcoholic patients than in healthy controls or patients with nonalcoholic liver disease. In alcoholic patients 2-keto[1-14C]isocaproic acid decarboxylation was impaired in the presence of normal conventional and quantitative liver function as assessed by aminopyrine breath test and galactose elimination capacity, indicating that 2-keto[1-14C]isocaproic acid decarboxylation does not simply reflect decreased functional liver mass. We conclude that mitochondrial function as reflected by 2-keto[1-14C]isocaproic acid decarboxylation is impaired in chronic alcoholic patients. The functional impairment is specific for excessive ethanol consumption and not a reflection of decreased global liver function or the presence of cirrhosis. 2-Keto[1-14C]isocaproic acid decarboxylation could thus be useful as a marker of excessive ethanol consumption. (HEPATOLOGY 1993;17:418–422.)
ABSTRACTS FROM THE LITERATURE
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Journals in jeopardy
Authors: M. D. O'Connell
Journal: JAMA (1979)

<h3>To the Editor.—</h3> The article by Beecham et al (241:1013, 1979), "<i>Salmonella typhimurium</i>: Transmission by Fiberoptic Upper Gastrointestinal Endoscopy," is an important reminder to endoscopists that their instruments may infect patients. However, when discussing possible sources of infection, the authors failed to mention culturing the endoscopy wash bottle, a reservoir common to all procedures. The antifoaming simethicone solution routinely placed into the wash bottle may also be source of contamination. The wash bottle should be regularly disinfected, and the simethicone solution should be discarded after its expiration date.
Erratum
Journal: BMJ (1899)

Queri, answers, and communication.relating to subjects to which special departments of the BlRMSH MEDICAL JOURNAL are devoted wiU be' found under their respective headings.A. desires to hear of an institution where the Schott treatment could be carried out in London (N.).M.B. wants information about a suitable place for a chronic inebriate who will not consent to go to any large or public home.H. J. W. will be glad if any one can inform him of some way of preventing ants getting into a house and overrunning store cupboards, etc. ?He has been much bothered with them for the last few weeks."RUSTIC " would be obliged if any country member would say if he has used an American buggy or American gig in his practice and if satis- factory.G. P. would be glad to know of any institution or home where a female, aged 25, a confirmed epileptic