AB1763-HPR RELIABILITY AND VALIDITY OF THE TURKISH VERSION OF SCLERODERMA SKIN PATIENT-REPORTED OUTCOME IN PATIENTS WITH SYSTEMIC SCLEROSIS
Authors: F. Sarİ, Z. Bazancİr Apaydİn, H. Apaydin, M. Kayaalp, A. Erden, S. C. Güven, B. Armagan, A. Omma, O. Küçükşahin
Journal: Annals of the Rheumatic Diseases (2023)

<h3>Background</h3> Systemic sclerosis (SSc), which is characterized by fibrosis of the skin and, internal organs and vasculopathy, is an autoimmune rheumatic disease. Skin fibrosis is the most seen feature of SSc patients and affects nearly all patients with SSc at different levels and severity. Skin involvement is generally evaluated with the modified Rodnan skin score (mRSS). However, several studies have indicated that there is no relation between mRSS and appearance self-esteem. Based on evidence from previous studies that it is significant to comprehensively evaluate the effects of skin fibrosis on QoL in SSc patients. There is a need for an instrument to assess the effects of skin involvement on the quality of life of the Turkish population in SSc patients. <h3>Objectives</h3> Scleroderma Skin Patient-Reported Outcome (SSPRO) is useful scale to evaluate the skin related quality of life in SSc patients. This study purposed to translate the SSPRO questionnaire to Turkish (SSPRO-T) language and to assess its validity and reliability. <h3>Methods</h3> Fifthy-four SSc patients (female:male, 51:3) participated in the reliability and validity analysis. The translation and cross-cultural adaptation of the original version of the SSPRO were applied in accordance with the procedure described by Beaton guidelines. The SSPRO-T, the Scleroderma Health Assessment Questionnaire (SHAQ), the Health Assessment Questionnaire Disability Index (HAQ-DI), Skindex-29 and patient global skin severity were conducted to 54 patients with SSc for construct validity. The SSPRO-T was re-tested to assess its reliability after seven days. <h3>Results</h3> The SSPRO-T had a four-factor structure. The total SSPRO-T score and its subgroups correlated positively with SHAQ, HAQ, Skindex-29 and patient global skin severity. The internal consistency and reliability were excellent the SSPRO-T and physical effects subgroup, emotional effect subgroup, physical limitation subgroup and social effect (Cronbach's α = 0.94, 0.80, 0.95, 0.93 and 0.84, respectively) (Table 1). The SSPRO-T had excellent test-retest reliability (r=0.91, p&lt;0.001). In addition; it was not seen floor effect and ceiling effect related SSPRO-T. <h3>Conclusion</h3> The SSPRO-T questionnaire is an excellent a reliable and valid tool. It could be used in research and clinical studies in the Turkish patients with SSc. <h3>References</h3> [1]Hudson, M., et al., Health-related quality of life in systemic sclerosis: a systematic review. Arthritis Rheum, 2009. 61(8): p. 1112-1120. [2]Man, A., et al., Development and validation of a patient-reported outcome instrument for skin involvement in patients with systemic sclerosis. Ann Rheum Dis, 2017. 76(8): p. 1374-1380. [3]Beaton DE, Bombardier C, Guillemin F, Ferraz MB Guidelines for the process of cross-cultural adaptation of self-report measures. Spine (Phila Pa 1976), 2000. 25(24):3186-3191. <h3>Acknowledgements:</h3> NIL. <h3>Disclosure of Interests</h3> None Declared.