tbuckley/cabot-search huggingface dataset:
Acid-Base Imbalance in Pulmonary Edema
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cardiorespiratory Effects of Volume- and Pressure-controlled Ventilation at Various I/E Ratios in an Acute Lung Injury Model
Authors: Harald Mang, Robert M. Kacmarek, Ray Ritz, Roger S. Wilson, William P. Kimball
Journal: American Journal of Respiratory and Critical Care Medicine (1995)

Numerous approaches to the provision of mechanical ventilation during acute lung injury are currently available. Of these, pressure control inverse ratio ventilation has been considered superior to volume control ventilation with PEEP with respect to improving gas exchange and minimizing cardiovascular compromise. However, no study systematically compares volume-controlled (VC) and pressure-controlled (PC) ventilation while maintaining mean airway pressure (MAP) constant at varying I/E ratios. We studied the effect of VC and PC with PEEP at normal (1:2) and inverse I/E ratios (2:1 and 4:1) on gas exchange, lung mechanics, and hemodynamics in a sheep lung injury model. Severe lung injury was induced in 12 sheep with bilateral lung lavages using normal saline; prelavage PO2 230 ± 50 mm Hg, PEEP 5 cm H2O and postlavage, pretreatment PO2 70 ± 20 mm Hg, PEEP 10 cm H2O, both at FiO2 0.50. MAP was kept constant throughout the study at 25 ± 2 cm H2O while ventilating all animals with a Vt of 10 ml/kg and a rate of 20/min by randomized application of VC and PC with I/E ratios of 1:2, 2:1, and 4:1. Despite liberal fluid administration, all ventilatory modes depressed cardiac output compared with preinjury values. However, gas exchange and hemodynamics did not differ among ventilation modes or I/E ratios. Of all the parameters investigated, the most striking changes occurred in peak inspiratory pressure (PIP) and PEEP: PC (I/E 2:1 and 4:1) resulted in significantly (p < 0.05) lower values for PIP and applied PEEP compared with control data (VC I/E ratio 1:1), and VC (I/E 4:1) resulted in significantly (p < 0.05) lower values for applied PEEP than VC I/E ratio 1:1. Auto PEEP levels during PC (I/E ratio 2:1 and 4:1) and VC (I/E 2:1 and 4:1) were significantly higher (p < 0.05) than VC I/E ratio 1:1. When MAP remained constant, alterations in the ventilation mode (PC or VC) or I/E ratio (1:2 to 4:1) produced no significant change in hemodynamic, oxygenation, or ventilation parameters in this sheep model.
Transfusion Medicine
Authors: Colleen Gorman Koch
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Myeloid Growth Factors Clinical Practice Guidelines in Oncology
Authors: Jeffrey Crawford, Betsy Althaus, James Armitage, Douglas W Blayney, Spero Cataland, David C Dale, George D Demetri, James Foran, Mark L Heaney, Sally Htoy, Dwight D Kloth, Gary H Lyman, Laura Michaud, Susannah Motl, Saroj Vadhan-Raj, Michael K Wong
Journal: Journal of the National Comprehensive Cancer Network (2005)

Chemotherapy-induced neutropenia is the major dose-limiting toxicity of systemic cancer chemotherapy, associated with substantial morbidity, mortality, and cost. Although prophylactic colony-stimulating factors (CSFs), can reduce this complication, their routine use in all patients on myelosuppressive chemotherapy is prohibitively costly. Selective use in patients most at risk for neutropenia may enhance cost-effectiveness, but determining the actual risk is complicated by issues in reporting myelosuppression and dose intensity, among other factors. For this reason, NCCN experts developed these guidelines to assist practitioners in the appropriate prophylactic use of CSFs. For the most recent version of the guidelines, please visit NCCN.org
The Passing of the Family Doctor
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Women, children, and global public health: beyond the millennium development goals
Journal: BMJ (2015)

h1755), the millennium development goal for reducing maternal mortality was incorrectly described as goal three, when it was actually goal five.The text should have read: "Each goal had specific targets, some of which were quantified-for example, goals four and five aimed for reductions in child and maternal mortality of two thirds and three quarters, respectively, from their rates in 1990.
Trade/Brand Name Index
Authors: Cannula Caddy, Coaxial Ophthalmoscope, Welch Allyn, Carl Zeiss, Inc Magnivision, Katena Products, Keeler Loop, Keeler Panoramic C-Loop, Kimberly -Clark Drapes, Kimberly-Clark Corporation, Kimberly -Clark Lab Coats, Kimberly-Clark Surgical Gowns, Kimguard Sterile-Wrap, Bifixation Kremer, Kremer Blade Gauge, Kremer Corneometer, R Program, Trephines Kremer
Journal: Ophthalmology (1990)
Haematology
Authors: A. M. Peters, S. M. Lewis
Journal: Clinical Nuclear Medicine (1991)

Since the previous edition of this book the field of nuclear haematology has expanded considerably as a result of the introduction of new techniques for labelling blood cells, particularly platelets and leucocytes. These have led, for example, to improved methods for identifying and quantifying the causes of thrombocytopenia in the clinical setting and for understanding the normal kinetics of platelets and granulocytes in the context of clinical research.
MIGRAINE
Authors: PETER BASSOE
Journal: JAMA (1933)

Thanks to the financial support of the Josiah Macy, Jr., Foundation, Riley<sup>1</sup>has been enabled to contribute a review of 100 pages covering all important contributions from antiquity to the year 1932. Since then, a valuable article by Critchley and Ferguson<sup>2</sup>has appeared as the opening paper of a discussion at the Harveian Society of England. Riley defines migraine as "a periodic incapacitating headache culminating in nausea or vomiting, often preceded by visual disturbances, followed by sleep and occurring against a background of relatively perfect health." Riley makes the reservation that this definition is not an absolute one, since many cases fail to present any one or several of these characteristics. The history of migraine does not begin with Hippocrates but in the first century of the Christian era with a description of "heterocrania" by Aretaeus of Cappadocia. About fifty years later Galen introduced the term "hemicrania." During
LISTER
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Paclitaxel (Taxol)
Authors: Eric K. Rowinsky, Ross C. Donehower
Journal: New England Journal of Medicine (1995)

The taxanes are an important new class of anticancer agents that exert their cytotoxic effects through a unique mechanism. Paclitaxel (Taxol), the first taxane in clinical trials, is active against a broad range of cancers that are generally considered to be refractory to conventional chemotherapy. This has led to the regulatory approval of paclitaxel in the United States and many other countries for use in the palliative therapy of patients with ovarian and breast cancers resistant to chemotherapy. The challenge now is to develop strategies using paclitaxel in the initial therapy of cancers in which cure or improved survival may . . .
Viral Gastroenteritis—South Dakota and New Mexico
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract P292: Age at Menarche, Weight Change From Young Adulthood to Middle Age, and Adult Adiposity: Evidence From The Hong Kong Women’s Health Study
Authors: Yao Jie Xie, Suzanne C. Ho
Journal: Circulation (2016)

Background: Previous studies have shown that early menarche is associated with elevated adiposity in adulthood. This relationship was not well-examined in Hong Kong Chinese women. The purposes of this study were: 1) to examine the associations between age at menarche and adult body mass index (BMI) and adiposity; 2) to determine whether weight change from age 18 to middle age modifies the relationship between early menarche and adult adiposity. Methods: A life-course epidemiology study named “Hong Kong Women’s Health Study” was conducted among Chinese female nurses in Hong Kong. Three rounds of mail surveys were implemented and 1253 nurses aged 35 to 65 years were involved in this study. Age at menarche, height, weight at age 18, current weight, waist circumference and other variables were collected by a self-administered questionnaire. Weight change was calculated as current weight minus weight at age 18. The self-reported anthropometric variables have been validated in a pilot study. Results: The mean age at menarche was 12.5±1.4 years. Nearly one fourth (23.9%) of the women had early menarche (≤11 years). The mean weight change was 5.8±6.8 kg. Women with early menarche had higher body weight at age 18 (51.6 kg vs. 48.6 kg, p&lt;0.001) but lesser weight change from age 18 to current (5.0 kg vs. 6.0 kg, p&lt;0.05) than those without early menarche. Using regression analyses, after adjustment for age, height, and physical activity, one year increase in age at menarche was associated with 0.21 kg/m2 decrease in BMI (95% CI: -0.33 to -0.09, p&lt;0.001); early menarche was significantly associated with overweight/obesity (OR=1.64, 95% CI: 1.23 to 2.19, p&lt;0.01) and central adiposity (OR=1.73, 95% CI: 1.29 to 2.32, p&lt;0.001). All these associations were strengthened after further adjustment of weight change (all p&lt;0.01). In the stratified analysis, the ORs were 1.49 and 1.68 for overweight/obesity and central adiposity in weight gain group (gained weight &gt; 1 kg), and 2.85 and 1.69 in weight loss group (lost weight &gt; 1 kg), respectively (all p&lt;0.05). Conclusions: Our study indicated that early menarche predicted greater BMI and elevated adiposity in adulthood. This association could not be eliminated by weight change status, even if the women had reduced body weight from young adulthood to middle age.
Annual and Analytical Cyclopedia of Practical Medicine.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Health effects in survivors of the Chernobyl disaster
Authors: M. R. Quastel
Journal: JAMA (1996)

<h3>In Reply.</h3> —Dr Quastel and colleagues are to be commended for establishing a comprehensive research program addressing the Chernobyl health effects among immigrants to Israel. Their findings are similar to those of investigators from Japan, Belarus, Russia, Ukraine, the World Health Organization, the International Atomic Energy Agency, and the International Consortium for Research on the Health Effects of Radiation. The concept of linking the Israeli cancer registry to a registry of immigrants from the affected regions has significant promise. Given that Israel is a geographically small country with an excellent coordinated health care system and resettlement effort, researchers in Israel have a unique opportunity to monitor the long-term effects of previous exposure. While our registry in the United States has only recently begun operating, we hope it too may play a role in tracking the long-term effects and perhaps provide a mechanism for cohort identification for future studies. This is
BUG VERSUS DRUG
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"THE MODE OF PRODUCTION OF THE SO-CALLED VESICULAR MURMUR OF RESPIRATION"
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A decision analysis of alternative treatment strategies for clinically localized prostate cancer. Prostate Patient Outcomes Research Team
Authors: C. Fleming
Journal: JAMA (1993)

<h3>Objective.</h3> —To model the impact of initial therapy on outcomes for men with localized (clinical stage A or B) prostatic carcinoma. <h3>Design.</h3> —A decision analysis modeling three strategies: radical prostatectomy, external-beam radiation therapy, and watchful waiting, with delayed hormonal therapy if metastatic disease develops. We modeled the main benefit of treatment as a reduction in the chance of death or disutility from metastatic disease. These benefits were offset in the model by the risks of treatment-related morbidity and mortality. The model was used to analyze expected outcomes by tumor grade (well, moderately, and poorly differentiated) for men 60 to 75 years of age. <h3>Data.</h3> —Probabilities and rates for important clinical events, obtained through review of the literature for prostatic carcinoma and analysis of Medicare claims data. <h3>Main Results.</h3> —Several patterns emerged within the range of uncertainty about the risks and benefits of treatment for prostatic carcinoma. In patients with well-differentiated tumor grades, based on clinical staging, treatment at best offers limited benefit in terms of quality-adjusted life expectancy and may result in harm to the patient. Among patients with moderately or poorly differentiated tumors, if we use the most optimistic assumptions about treatment efficacy, then patients aged 60 to 65 years would benefit from either radical prostatectomy or external-beam radiation therapy, compared with watchful waiting. However, in most other cases, treatment offers less than a 1-year improvement in quality-adjusted life expectancy or decreases the quality-adjusted life expectancy compared with watchful waiting. Invasive treatment generally appears to be harmful for patients older than 70 years. <h3>Conclusions.</h3> —Radical prostatectomy and radiation therapy may benefit selected groups of patients with localized prostate cancer, particularly younger patients with higher-grade tumors. However, our model shows that in most cases the potential benefits of therapy are small enough that the choice of therapy is sensitive to the patient's preferences for various outcomes and discounting. The choice of watchful waiting is a reasonable alternative to invasive treatment for many men with localized prostatic carcinoma. (<i>JAMA</i>. 1993;269:2650-2658)
Erratum: “Prenatal Organophosphate Pesticide Exposure and Traits Related to Autism Spectrum Disorders in a Population Living in Proximity to Agriculture”
Authors: Sharon K. Sagiv, Maria H. Harris, Robert B. Gunier, Katherine R. Kogut, Kim G. Harley, Julianna Deardorff, Asa Bradman, Nina Holland, Brenda Eskenazi
Journal: Environmental Health Perspectives (2018)

[This corrects the article DOI: 10.1289/EHP2580.].