Age at Diagnosis in U.S. Adults With Type 1 Diabetes
Authors: Michael Fang, Dan Wang, Justin B. Echouffo-Tcheugui, Elizabeth Selvin
Journal: Annals of Internal Medicine (2023)

Letters26 September 2023Age at Diagnosis in U.S. Adults With Type 1 DiabetesMichael Fang, PhD, MHS, Dan Wang, MS, Justin B. Echouffo-Tcheugui, MD, PhD, Elizabeth Selvin, PhD, MPHMichael Fang, PhD, MHSDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MarylandSearch for more papers by this author, Dan Wang, MSDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MarylandSearch for more papers by this author, Justin B. Echouffo-Tcheugui, MD, PhDDivision of Endocrinology, Diabetes, and Metabolism, Johns Hopkins School of Medicine, Baltimore, MarylandSearch for more papers by this author, Elizabeth Selvin, PhD, MPHDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MarylandSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M23-1707 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Background: Adult-onset type 1 diabetes is frequently misdiagnosed as type 2 diabetes, leading to inappropriate care (1). Emerging data suggest that up to 62% of type 1 diabetes cases develop after age 20 years (2). However, prior studies have been done in selected clinical populations. Clarifying the burden of adult-onset type 1 diabetes in the general population may help reduce misdiagnosis.Objective: To characterize the age distribution of type 1 diabetes diagnosis in the United States, overall and according to demographic and clinical characteristics.Methods: The National Health Interview Survey (NHIS) is a nationally representative survey of the noninstitutionalized U.S. ...References1. Leslie RD, Evans-Molina C, Freund-Brown J, et al. Adult-onset type 1 diabetes: current understanding and challenges. Diabetes Care. 2021;44:2449-2456. [PMID: 34670785] doi:10.2337/dc21-0770 CrossrefMedlineGoogle Scholar2. Gregory GA, Robinson TI, Linklater SE, et al; International Diabetes Federation Diabetes Atlas Type 1 Diabetes in Adults Special Interest Group. Global incidence, prevalence, and mortality of type 1 diabetes in 2021 with projection to 2040: a modelling study. Lancet Diabetes Endocrinol. 2022;10:741-760. [PMID: 36113507] doi:10.1016/S2213-8587(22)00218-2 CrossrefMedlineGoogle Scholar3. National Center for Health Statistics. 2022 National Health Interview Survey (NHIS): Codebook for Sample Adult File. 5 June 2023. Accessed at https://ftp.cdc.gov/pub/Health_Statistics/NCHS/Dataset_Documentation/NHIS/2022/adult-codebook.pdf on 3 August 2023. Google Scholar4. Fang M, Jeon Y, Echouffo-Tcheugui JB, et al. Prevalence and management of obesity in U.S. adults with type 1 diabetes. Ann Intern Med. 2023;176:427-429. [PMID: 36780652] doi:10.7326/M22-3078 LinkGoogle Scholar5. Nooney JG, Kirkman MS, Bullard KM, et al. Identifying optimal survey-based algorithms to distinguish diabetes type among adults with diabetes. J Clin Transl Endocrinol. 2020;21:100231. [PMID: 32695611] doi:10.1016/j.jcte.2020.100231 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Michael Fang, PhD, MHS; Dan Wang, MS; Justin B. Echouffo-Tcheugui, MD, PhD; Elizabeth Selvin, PhD, MPHAffiliations: Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MarylandDivision of Endocrinology, Diabetes, and Metabolism, Johns Hopkins School of Medicine, Baltimore, MarylandGrant Support: By grants K24 HL152440 (Dr. Selvin) and HL153774 (Dr. Echouffo-Tcheugui) from the National Heart, Lung, and Blood Institute of the National Institutes of Health. The funders had no role in the design or conduct of the study; collection, management, analysis, or interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M23-1707.Reproducible Research Statement: Study protocol: Not available. Statistical code: Available from Dr. Fang (e-mail, mfang9@jh.edu). Data set: Publicly available at www.cdc.gov/nchs/nhis/2022nhis.htm.Corresponding Author: Elizabeth Selvin, PhD, MPH, Johns Hopkins Bloomberg School of Public Health, 2024 East Monument Street, Baltimore, MD 21205; e-mail, eselvin@jhu.edu.This article was published at Annals.org on 26 September 2023. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics LatestKeywordsDiagnostic accuracyEndocrinologyInsulinType 1 diabetes ePublished: 26 September 2023 Copyright & PermissionsCopyright © 2023 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...