POS0580-PARE PATIENT ADHERENCE TO OSTEOPOROSIS TREATMENT IS HIGHER WITH CAREGIVER EDUCATION
Authors: S. Samieva, J. Polyakova, L. Seewordova, E. Papichev, Y. Akhverdyan, В. Zavodovsky
Journal: Annals of the Rheumatic Diseases (2023)

<h3>Background</h3> Treatment adherence to osteoporosis treatment remains low. Additional factors: the elderly age of patients, congestive disorders, high comorbidity, fears of side effects of drugs, fear of calcium deposits in the vessels, kidneys and gallbladder, the absence of obvious clinical manifestations of the disease lead to refusal or unreasonable interruptions in therapy for osteoporosis. <h3>Objectives</h3> Еo analyze the Treatment adherence to osteoporosis therapy of single patients, patients living in a family and patients coming to an appointment with a caring relative. <h3>Methods</h3> The analysis of outpatient records of 300 patients observed in the center for the diagnosis and treatment of osteoporosis was carried out. The study included all patients who visited the center in the period from the beginning of 2020 until reaching the enrollment of 100 people according to the ranked criterion. A total of 3 groups were recruited: 1st - single patients, N=100, 2nd - living in a family N=100, 3rd - coming to an appointment with a caring relative/social worker, N=100. The following were assessed: the completeness of the examination, the frequency of subsequent visits, adherence to therapy and the result of treatment according to densitometry data and repeated fractures. The observation period is 3 years. Patients who did not come to the follow-up examination (DXA) after 3 years were excluded from the study. <h3>Results</h3> 15.7% (47 people) withdrew from the study due to non-appearance for return visits. When calling patients, it was found that 6% (18 people) were going to start treatment, but did not start for various reasons, 9.7% (29) started taking vitamin D and continued to take it until the package was over, 5% (15 people) started taking vitamin D preparations (patients from 9.7% of the above) and calcium preparations were taken from 1 to 3 months, after which they stopped taking them, considering that the course of treatment was completed. 2.3% (7 people) died within 3 years from various causes (4 out of 1 gr, 1 out of 2, 2 out of 3). The final statistical analysis included 246 people. The results are presented in Table 1. <h3>Conclusion</h3> As a result of the analysis, it was confirmed that the highest adherence to examination and therapy was in patients who applied with a caregiver. Caregivers perceive verbal information better, seek repeated clarifications more often when questions arise about therapy and examination results, help patients solve technical problems (get to the center, purchase medicine, calculate dietary calcium, find a physical education video course). As a result of higher adherence to non-pharmacological and pharmacological treatment, the increase in bone mineral density in the 3rd group of patients was maximum. In the 1st group of patients, due to low adherence to therapy and the worst arrangement of life, by the 3rd year of observation, a higher percentage of fractures (6.2%) was revealed, differences in the frequency of fractures in the 2nd and 3rd groups over 3 years observation was not detected (1.2% and 1.1%) due to the short observation period and a relatively small sample of patients. <h3>References</h3> [1]New coronavirus infection - direct and indirect effects on patients with diseases of the musculoskeletal system and connective tissue. Polyakova Yu., Papichev E., Akhverdyan Yu., et al. Modern problems of science and education. – 2021. – No. 6 – pp. 147-147. DOI 10.17513/spno.31342 [2]The level of awareness about osteoporosis as a method of improving primary prevention. Lezhenina S., Shuvalova N., Guryanova E. Annals of rheumatic diseases. 2021. Vol. 80. No. S1. p. 1482. DOI 10.1136/annrheumdis-2021-eular.3856 <h3>Acknowledgements:</h3> NIL. <h3>Disclosure of Interests</h3> None Declared.