AB1036 FACTORS ASSOCIATED WITH HIP INVOLVEMENT IN SPONDYLOARTHRITIS
Authors: S. Oulebsir, S. Affaf, S. Bennedjema, A. Djebbari, B. Abdelatif, M. Houbi, A. Abi Ayad, C. Makhloufi-Dahou
Journal: Annals of the Rheumatic Diseases (2023)

<h3>Background</h3> Hip involvement in spondyloarthritis determines a large part of the functional prognosis and affects negatively the patient's life. Identifying these factors could influence our management strategy by developing specific therapeutic protocols. <h3>Objectives</h3> The objective of this work is to determine the factors associated with hip involvement during spondyloarthritis. <h3>Methods</h3> The study is a single-center prospective observational study, carried out during the period extending between January 2020 and January 2022. Spa patients meeting the criteria for ASAS were included. On a patient-by-patient basis, clinical, biological, and imaging data were collected. <h3>Results</h3> In total, 259 patients with consecutive spondyloarthritis were assessed. Of these, 80 patients (30.88%) had hip involvement associated with spondyloarthritis, including 66 men and 14 women (gender ratio = 4.7), with an average age of 37.66 and 11.3 years. It was bilateral in 70% of cases, and inaugural in over half of patients (55% of cases). The biological inflammatory syndrome was observed in 72.5% of cases and HLA B 27 was found in ¾ of patients. The anatomio-radiological forms observed were: the destructive form (36.76%), the condensant constructive form (22.05%), the initial form (24.26%), and the synostotic form (16.91%). TNF alpha treatment was initiated in 85% of cases, with a third of patients receiving PTH. Factors related to hip involvement were: functional impotence (BASFI), limitation of spinal and joint mobility (BASMI, inter-malleolar distance), structural damage to the SpA (total BASRI), presence of HLA B27, and initiation of anti-TNF alpha treatment. On the other hand, the age of hip involvement and spa, gender, bilateral involvement, high scores of the BASDAI and ASDAS indices, and the presence of a biological inflammatory syndrome did not seem to be involved. <h3>Conclusion</h3> The occurrence of hip involvement during spondyloarthritis seems to be frequent in our country. Hip involvement is one of the elements of poor prognosis and its presence predicts a severe form of the disease. <h3>References</h3> [1]Ziadé N, El Hajj J, Rassi J, Hlais S, López-Medina C, Gamal SM, et al. Root joint involvement in spondyloarthritis: a post hoc analysis from the international ASAS-PerSpA study. Rheumatol Oxf Engl. 2 févr 2022;61(2):667‑78. [2]Zheng X. Differences between ankylosing spondylitis patients with and without radiographic hip involvement in china | Annals of the Rheumatic Diseases. Disponible sur: Annals of the Rheumatic Diseases 2017;76:664. [3]Jeong H, Eun YH, Kim IY, Kim H, Lee J, Koh EM, et al. Characteristics of hip involvement in patients with ankylosing spondylitis in Korea. Korean J Intern Med. janv 2017;32(1):158‑64. [4]Chen S, Deng L. Risk factors for radiological hip involvement in patients with ankylosing spondylitis. Rev Assoc Médica Bras. 19 nov 2021;67:1293‑8. <h3>Acknowledgements:</h3> NIL. <h3>Disclosure of Interests</h3> None Declared.