Diffuse Systemic Sclerosis
Authors: WILLIAM S. MIDDLETON
Journal: Annals of Internal Medicine (1962)

Article1 August 1962Diffuse Systemic SclerosisThe Alfred Stengel Memorial LectureWILLIAM S. MIDDLETON, M.D., M.A.C.P.WILLIAM S. MIDDLETON, M.D., M.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-2-183 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Excerpt"There are some who possess that intangible quality known as leadership, to whom all others turn for counsel, guidance, and inspiration. Such was Alfred Stengel, whose sudden and unexpected death on April 10, 1939, deprived American medicine of one of its most distinguished clinicians and robbed the American College of Physicians of a beloved and honored master as well as a loyal and ardent champion" (1).In these terms George Morris Piersol eulogized his late departed friend and long-time associate, whose professional life and activities were so intimately bound to the University of Pennsylvania School of Medicine and the American...References1. PIERSOL GM: Dr. Alfred Stengel. An appreciation. Ann. Intern. Med. 12: 1913, 1939. Google Scholar2. MIDDLETON WS: Some clinical expressions of diffuse collagen disorders. Med. Clin. N. Amer. 37: 1697, 1953. CrossrefGoogle Scholar3. DURAN-REYNALS F: Introduction—conference on the ground substance of the mesenchyme and hyaluronidase. Ann. N. Y. Acad. Sci. 52: 943, 1950. Google Scholar4. CROWLEY N: Hyaluronidase production by hemolytic streptococci of human origin. J. Path. 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Treatment of three cases of the non-calcific variety by chelation (EDTA). J. Invest. Derm. 29: 273, 1957. CrossrefMedlineGoogle Scholar39. PRICEBROWNRUKAVINAMENDELSONJOHNSON JMRRJGCSA: Scleroderma (acrosclerosis). II. Tryptophan metabolism before and during treatment by chelation (EDTA). J. Invest. Derm. 29: 289, 1957. CrossrefMedlineGoogle Scholar40. JOHNSON SA: Personal communication. Google Scholar41. ZARAFONETISLORBERHANSON CJSHSM: Association of functioning carcinoid syndrome and scleroderma. Amer. J. Med. Sci. 236: 1, 1958. CrossrefMedlineGoogle Scholar42. SCHERBELSCHMID ALEA: Effect of serotonin inhibitors on connective tissue disease. Cleveland Clin. Quart. 29: 1, 1962. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C.From the Department of Medicine and Surgery, Veterans Administration, Washington, D. C.Presented as the Alfred Stengel Memorial Lecture at the Forty-third Annual Session of The American College of Physicians, Philadelphia, Pennsylvania, April 9-13, 1962.Requests for reprints should be addressed to William S. Middleton, M.D., Department of Medicine and Surgery, Veterans Administration, Washington 25, D. C. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByImpotence in SclerodermaNANCY S. NOWLIN, M.D., JAMES E. BRICK, M.D., DANA J. WEAVER, M.D., DEBORAH A. WILSON, M.D., HOWARD L. JUDD, M.D., JOHN K. H. LU, Ph.D., HAROLD E. 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MONTGOMERY, M.D., F.A.C.P., CARL M. PEARSON, M.D., F.A.C.P., HUGH A. SMYTHE, M.D., F.R.C.P. (C), L. EMMERSON WARD, M.D., F.A.C.P., HOWARD J. WEINBERGER, M.D., F.A.C.P.Relapsing Polychondritis Clinical and Pathologic Features in Fourteen CasesRONALD L. KAYE, M.D., DONALD A. SONES, M.D. 1 August 1962Volume 57, Issue 2_Part_1Page: 183-197KeywordsHypertensionSclerodermaSurgery Issue Published: 1 August 1962 CopyrightCopyright ©, 1962, by The American College of PhysiciansPDF DownloadLoading ...