tbuckley/cabot-search huggingface dataset:
JAMA Pediatrics
Authors: Phil Fontanarosa, Annette Flanagin, Brenda Gregoline, Tracy Frey, Shannon Sparenga, Nicole Balin, Miriam Cintron, Paul Ruich, Diane Cannon, Connie Manno, Fred Marshall, Laura Copyreaders, Catherine Adamczyk, Stephanie Alden, Jan Beckmeyer, Mary Clavey, Paula Coerver-Connolly, Roya Glitman, Laura Khatiblou, Donna King, Caroline Thordsen, Wanda Assistant, Larry Bryant, Monica Mungle, Elaine Williams, Lenette Gardner-Gullens, Fanny Brown, Paul Frank, Peter Kim, Rachell Lozano, Michaela Mark, Kathryn Muskovich, Gale Saulsberry, Michael Berkwits, Michelle Kurzynski, Eric Butkus, Will English, Christopher Hastings, Craig Mccaffrey, Reuben Rios, Ronna Henry, Joshua Bird, Karen Bucher, David Song, Deputy Livingston, Thomas Cole, Marla Hall, Deanna Willis, Yolanda Davis, Joseph Thornton, Preeti Malani, Deanna Bellandi, Jim Periodical, Thomas Easley Vice, Brian Shields, Monica Smith, Jeffery Bonistalli Manager, Kathy Russell, Mirna Monal, Tim Melroy, Thalia Moss, Mike Harvey, Susan Henning, Mark Thornbury, Tricia Castellano, Saskia Bolore, Gretchen Linder, Brian Mccartney, David Baum, Rebecca Haas, Christine Hearne, Irma Lara, Ron Marketing, Paul Gee, Matt Herron, Elizabeth Solaro, Geoffrey Flick Managers, Rick Bell, Lindsay Dawson, Michael Mcgraw, Sara Nagy, Romando Rossini, Stacy Staff, Millette Jackson-Bates, Karen Adams-Taylor, Karl Elvin, Jaye Mize, Sean O'donnell, Sue Managers, David Antos, Chris Borden, Debbie Camp, Lydia Cruz, Scott Curl, Diane Darnell, Colleen Kelly, Chris Meyer, Annemarie Neff, J Neff, Sean Ohlson, Phil O'leary, Susan Price, Denise Steinhauser, Production Services, Kim Boler, Rhonda Brown, Timothy Burke, Daniel Degroot, Jordynn Farrar, Euwanaha Joiner-Smith, Tiffany Jones, Cindy Rendlen, Ellen Yoshihara, Circulation Services, Julie Burton, Dexter Golden, Erin Hinchcliff, Maria Nienhaus, Noemi Rivera, Geneine Van, Someren Composition, New Media, Gail Barrett, Regina Brownlee, Amanda Camino, Brenda Chandler-Grayer, Emily Dunn, Amy Evers, Teri Hutchison, Mary Kuranda, Joshua Lampinen, Patricia Panek, La Son, Diggs Sledge, George Thomson Graphics, Joe Amft, Maria Duda, Fred Furtner, Carolyn Hall, Maria Kowalkowski, Proofreading Carol, Joy Farrell, Daniel James, Judith Literskis, Teresa Omiotek, James Madara, Bernard Hengesbaugh, Dimitri Christakis, Washington Joffe, Ron Keren, Debra Palazzi, Suzanne Shuey, Samir Shah, Howard Bauchner, Frederick Rivara, Joyce Lee, Ann Arbor, Jay Berry, Cherrie Boyer, San Francisco, Maria Britto, John Campo, Aaron Carroll, Indiana Frank, Joseph Chaloupka, Mitchell Cohen, Kathleen Janz, Iowa City, Terry Klassen, Michigan Michelle, Huckaby Lewis, Aaron Milstone, Shawn Rangel, Martha Sola-Visner, Jean-Claude Carel, Shabir Madhi, Ben Marais, Frank Oberklaid, Susan Sawyer, Joan-Carles Surís
Journal: JAMA Pediatrics (2015)
Gastric Cancer Clinical Practice Guidelines in Oncology
Authors: Jaffer Ajani, Thomas A D'Amico, James A Hayman, Neal J Meropol, Bruce Minsky
Journal: Journal of the National Comprehensive Cancer Network (2003)

Carcinomas originating in the upper gastrointestinal tract constitute a major health problem around the world. In fact, experts estimate that approximately 34,700 new cases of upper gastrointestinal carcinomas and 25,000 deaths will have occurred in the United States in 2002. This article summarizes the NCCN clinical practice guidelines for managing gastric cancer, which portray uniformity in the systemic approach to cancer in the United States. The article also discusses anticipated future advances in the treatment of gastric carcinoma. For the most recent version of the guidelines, please visit NCCN.org
Iatrogenic collapse.
Authors: K M Huntington
Journal: BMJ (1979)

Surely the classical process is from the general to the particular, and by going from the particular to the general they have got the process upside down.Either disease is a "unified concept" or it is not a concept at all.To end with I will ask two questions.How do they define the corresponding concept health?Is it possible that we are all, lay and professional alike, pursuing a mirage in our National Health Service ?
Questioning Protocol
Authors: Randi Redmond Oster
Journal: JAMA Internal Medicine (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Wound Healing
Authors: G. A. Stephens
Journal: BMJ (1941)

Thank you for your interest in spreading the word about The BMJ.NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Username * Your Email * Send To * You are going to email the following Wound Healing Your Personal Message CAPTCHA This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
'Melanoma? It can't be melanoma!' A subset of melanomas that defies clinical recognition
Authors: W. K. Andersen
Journal: JAMA (1991)

We diagnosed histologically 178 cases of malignant melanoma in 1990. Thirteen cases were recorded in which the diagnosis of malignant melanoma was not considered by the clinician prior to biopsy or, in retrospect, following pathologic diagnosis. Eight of the 13 lesions were amelanotic. The majority were deeply invasive at the time of biopsy, implying poor prognosis. Despite improvements in early detection of malignant melanoma, a significant subcategory of melanomas escapes clinical diagnosis. (<i>JAMA</i>. 1991;266:3463-3465)
Preoperative biochemical screening.
Journal: BMJ (1988)

was plainly evident that enalapril had considerably improved the quality of life and possibly prolonged it in many seriously ill patients" but give no data to support this observation.Every method of assessing the benefit risk profile of a new chemical entity has its drawbacks, but we believe that the yellow card reports, prescription-event monitoring, and properly conducted postmarketing studies each contribute to our knowledge, albeit in different ways.In attempt- ing to compare different methods care must be exercised to ensure legitimacy of the conclusions.
CALCIUM IN THE BLOOD
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Everolimus in patients with advanced pancreatic neuroendocrine tumors (pNET): Updated results of a randomized, double-blind, placebo-controlled, multicenter, phase III trial (RADIANT-3).
Authors: J. R. Strosberg, J. Lincy, R. E. Winkler, E. M. Wolin
Journal: Journal of Clinical Oncology (2011)

4009 Background: In the RADIANT-3 trial, everolimus, an oral inhibitor of mTOR, significantly prolonged progression-free survival (PFS) in pts with advanced pNET (ESMO 2010, Abstract #LBA9). Updated safety and exploratory biomarker analyses from this trial are presented. Methods: Pts with progressive, advanced low- or intermediate-grade pNET were randomized to everolimus 10 mg/d orally (n=207) or placebo (n=203); both arms received best supportive care. The primary endpoint was PFS (RECIST v1.0). Results: Median PFS by investigator assessment with everolimus was 11.0 mo vs with 4.6 mo with placebo (HR=0.35; 95% CI, 0.27-0.45; p<0.0001), resulting in a 65% reduction in the risk for progression. Everolimus compared with placebo resulted in a rapid and significant (p<0.001) reduction in baseline biomarkers, including chromogranin A, neuron-specific enolase, gastrin, and glucagon. Treatment arms were well balanced with respect to on-study somatostatin analog (SSA) use (39%, everolimus arm; 40%, placebo arm). An improvement in median PFS was observed with everolimus vs placebo in pts who received on-study SSA (11.4 mo vs 3.9 mo; HR=0.40; 95% CI, 0.29-0.56) and those without on-study SSA (10.8 mo vs 4.6 mo; HR=0.35; 95% CI, 0.24-0.50). Median safety follow-up is now 20.1 mo. Most common drug-related adverse events (AEs) with everolimus vs placebo were stomatitis (52.9% vs 12.3%), rash (48.5% vs 10.3%), diarrhea (34.3% vs 10.3%), and fatigue (32.4% vs 14.3%). The most common grade 3-4 AEs were anemia (5.9% vs 0%), hyperglycemia (5.9% vs 2.5%), stomatitis (4.9% vs 0%), and thrombocytopenia (3.9% vs 0%). Conclusions: In the RADIANT-3 trial, the largest randomized controlled trial ever completed in pts with progressive advanced pNET, everolimus provided a significant increase in median PFS, irrespective of SSA use, and significant reductions in tumor and secretory biomarkers. Oral stomatitis represented the most common drug-related AE; however, grade 3-4 somatitis was rare. These emerging data, including longer follow-up safety data, support the use of everolimus as a standard of care for pts with progressive, advanced pNET.
The influence of cholestyramine on thyroxine absorption
Authors: R. C. Northcutt
Journal: JAMA (1969)

Cholestyramine resin, an anionic exchange resin, currently being investigated as an agent for lowering serum cholesterol levels, has been shown to interfere with the absorption of ingested thyroid hormone. A small quantity of the resin is capable of binding thyroxine under the conditions encountered in the gastrointestinal tract. Interference with thyroid hormone absorption by cholestyramine can be minimized by allowing a time interval of at least four hours between the ingestion of the two agents. Hypothyroid patients receiving cholestyramine should be examined periodically for evidence of hypothyroidism, and adjustments in dose and time interval between the two agents should be made if malabsorption of thyroid hormone is significant.
THE ARMY MEDICAL DEPARTMENT OF THE FUTURE.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
QUARANTINE AND ISOLATION IN INFLUENZA
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Incorrect Age for Screening Reported in: Direct-to-Consumer Cardiac Screening and Suspect Risk Evaluation
Authors: Dario Giugliano, Katherine Esposito
Journal: JAMA (2011)

ter outcomes, even in terms of reduction of unnecessary inertia.Treatment intensity may therefore range from the most intensive (HbA 1c target Յ6.5%) to the least intensive (~8%) depending on a variety of clinical and psychosocioeconomic factors, including although not limited to age, stage of disease, propensity to hypoglycemia, and living situation. 3 Our Commentary was not was an apologia of inaction.We realize that inadequate treatment may occur and for many reasons, including those indicated by Mohan and Phillips.However, current uncertainty in medicine may amplify clinical inertia.William Osler affirmed more than a century ago that "medicine is a science of uncertainty."The Institute of Medicine acknowledges the existence of conditions of uncertainty regarding optimal individual treatment decisions. 4As irreducible uncertainty is a fact of life, "physicians will always need to extrapolate beyond available evidence in their attempts to tailor treatments to individual patients." 5Clinical inertia is at the crossroads between the perils of excessive medical care and the danger of clinical inaction.The art of medicine (a mixture of clinical experience, knowledge, and skill) may help overcome unnecessary clinical inertia.
Steatorrhea in Addison's Disease
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Description of the Johns Hopkins Hospital.
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Obstetrics as a Branch of Education
Authors: R. J. Kinkead
Journal: BMJ (1878)

GENTLEMEN,-Before commencing this course of lectures, a little time will be well spent in considering, not only what it is we shall have to study during the ensuing term, but also the position our subject occupies in medical science, its history, and its importance.On its importance to your future patients should, on its importance to you as studeats now, as practitioners hereafter, will, in a great measure, depend the amount of study and attention you will bestow on it.Our study is the generative system of the female the changes produced therein by pregnancy and morbid processes the phenomena of labour, both normal and abnormal ; and the duties of the physician in connection therewith.Everything connected with pregnancy and labour comes under the domain of midwifery; with departure from the normal standard in the unimpregnated under that of diseases of women.The scientific synonyms are obstetrics and gyneecology.To teach you their physiology and pathology, diagnosis and treat- ment, would require not one, but many courses of lectures.Unfortunately, it is too much the habit now, as it was altogether formerly, to
More Health Advice Needed to Cut US Sodium Intake
Journal: JAMA (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SHOULD PHYSICIANS STUDY LATIN?
Journal: JAMA (1891)

In the day when medicine was held to be one of the learned professions, and Latin an essential part of a gentleman's education, this would have seemed a superfluous question. Times have changed since then. The physician of the present time knows many things of which his predecessor of a century or two ago was ignorant, that are of more importance to his patients tnan a dead language, but even when liberally educated it is apt to be the case that he is less of what is called a scholarly man than those of corresponding standing in times when the requirements of strictly professional education were less exacting. That the gain has been, on the whole greater than the loss, there can be no doubt, and the question becomes more and more a serious one, which, among the ever increasing multitude of things that it is desirable for a physician
A rat model of acute liver necrosis induced by a monoclonal antibody to liver-specific antigen and complement
Authors: T Ikeda
Journal: Hepatology (1991)

Acute massive hepatic injury was induced in rats by a monoclonal antibody against a rat liver–specific membrane antigen, and its histological characteristics were investigated. A single intravenous injection of murine ascites containing a monoclonal antibody produced numerous hemorrhagic foci of degenerated and necrotic liver cells predominantly in zones 1 (the periportal area) and 2 (the area of transition between the periportal zone and the perivenular zone) of the liver lobule within 10 min. Massive hepatocellular necroses were observed 1 hr later, but no inflammatory cell infiltration occurred in and around the necrotic foci. Immunohistological study demonstrated marked deposition of the third component of the complement system in the necrotic area. Serum complement activity was sharply decreased immediately after the injection of the antibody, suggesting that the hepatic necrosis is ascribable to a complement-mediated immune attack on the liver cell membrane induced by the antigen-antibody reaction. The hepatic necrosis in response to monoclonal-antibody injection did not progress to a chronic disease and healed almost completely, changing to scar tissues within 2 wk. Although it is not clear whether this hepatic injury has any clinical relevance, this antibody/complement model may be useful for investigating the cause and therapy of hepatic diseases such as fulminant hepatitis. (HEPATOLOGY 1991;13:1152–1157.)
Toward suicide prevention in medical practice
Authors: J. A. Motto
Journal: JAMA (1969)

Current developments in health care place the nonpsychiatric physician more and more in a pivotal position regarding the identification and management of depressed and suicidal persons. It is essential that the physician resolve his own anxiety about suicide in order to function most efficiently in this role. Only when this is achieved will principles of management and treatment have value. An active case-finding approach, comparable to the routine chest x-ray film, serology, or Papanicolaou smear, is needed to effectively modify these suicidal states before they develop to crisis proportions. To further this goal, it is suggested that inquiry about depressive and suicidal states be made an essential part of every routine medical examination.