tbuckley/cabot-search huggingface dataset:
Clinicopathologic Predictors of Hypomethylating Agent Failure in Patients with Myelodysplastic Syndromes
Authors: Kelly S. Chien, Samuel Urrutia, Ziyi Li, Rashmi Kanagal-Shamanna, Ahmed Abdelhakeem, Tareq Abuasab, Emmanuel Almanza, Georgina Gener-Ricos, Alex Bataller, Alexandre Bazinet, Guillermo Montalban-Bravo, Nicholas J. Short, Elias Jabbour, Tapan M. Kadia, Farhad Ravandi, Gautam Borthakur, Danielle E. Hammond, Mahesh Swaminathan, Koji Sasaki, Xiao Qin Dong, Sherry Pierce, Hagop M. Kantarjian, Guillermo Garcia-Manero
Journal: Blood (2023)
DEK Regulates B-Cell Proliferative Capacity and Is Associated with Aggressive Disease in Low-Grade B-Cell Lymphoma
Authors: Melissa A. Hopper, Abigail R. Dropik, Janek S. Walker, Joseph P. Novak, Miranda S. Laverty, Michelle Manske, Xiaosheng Wu, Kerstin Wenzl, Jordan Edward Krull, Vivekananda Sarangi, Matthew J. Maurer, Thomas M. Habermann, Brian K. Link, Lisa M. Rimsza, Thomas E. Witzig, Stephen M Ansell, James R. Cerhan, Dragan Jevremovic, Anne J. Novak
Journal: Blood (2023)
Sustained MYB Activity Is Necessary for Oncogenic Transcription in <i>KMT2A</i>-Rearranged Acute Lymphoblastic Leukemia through Enhancer-Promoter Interactions and Epigenetic Modifications at Enhancers
Authors: I-Jun Lau, Joe R Harman, Nicole E Jackson, Nicholas Denny, Alastair L Smith, Paresh Vyas, James Oliver Davies, Jim Hughes, Nicholas Crump, Thomas Arthur Milne
Journal: Blood (2023)
The Transcriptional Landscape of Ph+B-ALL Is Orchestrated By Long-Range Enhancer-Promoter Interactions and the Coordinated Action of Phosphorylation-Dependent and Phosphorylation-Independent Transcription Factors
Authors: Han Leng Ng, Mark E Robinson, Valeria Malysheva, Ozgen Deniz, Nicholas Crump, Kadriye Nehir Cosgun, Kaiyue Helian, Mikhail Spivakov, Markus Müschen, Niklas Feldhahn
Journal: Blood (2023)
Using Peripheral Blood (PB) Measurable Residual Disease (MRD) Levels to Predict &amp;lt;0.01% Bone Marrow Disease (BM uMRD4): Identification of Effective PB Targets for CLL Treatment Cessation in the Ibrutinib+Venetoclax Arm of the FLAIR Trial
Authors: Andy Rawstron, Nichola Webster, Surita Dalal, Ruth M de Tute, Sue Bell, David Allan Cairns, Sean Girvan, Natasha Greatorex, Anna Hockaday, Sharon Jackson, David Phillips, David Stones, David Allsup, Adrian John Clifton Bloor, Anita Sarma, Abraham Mullasseril Varghese, Talha Munir, Peter Hillmen
Journal: Blood (2023)
Acute Events Significantly Increase Risk for Long-Term End-Organ Sequelae in Sickle Cell Disease - a Retrospective Cohort Study Using Optum Electronic Health Records
Authors: Xunming Sun, Steven Arkin, Yun Gu, Stephen E Schachterle, Xiaofeng Zhou, Thomas Edwards, Sherry Xiao, Kui A Huang
Journal: Blood (2023)
Experiences with Efanesoctocog Alfa: Exit Interviews with Caregivers of Previously Treated Patients with Hemophilia A from the XTEND-Kids Phase 3 Clinical Trial
Authors: Lynn Malec, Manuel Carcao, Mary Mathias, Nana Kragh, Jennifer Dumont, Annemieke Willemze, Linda Bystrická, Amanda Wilson, Dana Dibenedetti
Journal: Blood (2023)
Risk of Central Nervous System Vs. Systemic Relapse in Patients with Diffuse Large B-Cell Lymphoma Treated with R-CHOP: What Should We Focus on?
Authors: Magdalena Klanova, Samuel Hricko, Michal Masar, David Salek, Prokop Vodicka, Natasa Kopalova, Petra Blahovcova, Katerina Benesova, Jozef Michalka, Jan Koren, Andrea Janikova, Marek Trneny
Journal: Blood (2023)
Verlen, “Very Elderly Rituximab Associated to Lenalidomide - Tafasitamab Combination in Frontline DLBCL Patients”, a Phase II Open-Label Study Evaluating Efficacy of Lenalinomide and Tafasitamab Combination Associated to Rituximab in Frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or Older from the Lysa Group
Authors: Benoit Tessoulin, Julien Depaus, Pierre Feugier, Ludovic Fouillet, Julie Abraham, Sandy Amorin, Fabrice Jardin, Franck Morschhauser, Catherine Thieblemont, François-Xavier Gros, Bertrand Joly, Hacene Zerazhi, Sophie Bernard, Adrien Chauchet, Stéphane Vigouroux, Christophe Bonnet, Sarah Bailly, Steven Le Gouill
Journal: Blood (2023)
Tislelizumab, an Anti-PD1 Antibody, in Patients with Relapsed/Refractory Classical Hodgkin Lymphoma in Tirhol Bgb-A317-210: A Prospective Multicenter Lysa Phase 2 Study Conducted in Western Countries
Authors: Herve Ghesquieres, Krimo Bouabdallah, Marc Andre, Philippe Quittet, Cecile Borel, Aspasia Stamatoulas Bastard, Michael Gilbertson, Fabien Le Bras, Catherine Thieblemont, Baptiste Delapierre, Mohamed Touati, Pierre Feugier, Julien Lazarovici, Nadine Morineau, Thomas Gastinne, Isabelle Chaillol, Rod Ramchandren, Harsh Shah, Dipenkumar Modi, Heather Allewelt, Pierre Fustier, Jianfeng Xu, Amit Agarwal, Franck Morschhauser, Cedric Rossi
Journal: Blood (2023)
Harnessing TCR/CAR Antagonism to Enhance Immunotherapeutic Precision
Authors: Taisuke Kondo, François Bourassa, Sooraj Achar, Justyn DuSold, Pablo Cespedes, Madison Wahlsten, Audun Kvalvaag, Guillaume Gaud, Paul Love, Michael Dustin, Gregoire Altan-Bonnet, Paul François, Naomi Taylor
Journal: Blood (2023)
Low Mortality from COVID-19 Infection in Patients with B-Cell Lymphoma after Bispecific CD20xCD3 Therapy
Authors: Emil Ramsø Kyvsgaard, Anna Caroline Hasselbalch Riley, Michael Roost Clausen, Mads Harsløf, Line Dam Heftdal, Carsten Utoft Niemann, Kirsten Grønbæk, Martin Hutchings, Simon Husby
Journal: Blood (2023)
Distinct Cellular, Transcriptional, and Mechanistic Properties Determine HSC Fate during Emergency Granulopoiesis
Authors: Karolina Vanickova, Mirko Milosevic, Irina Ribeiro Bas, Monika Burocziova, Asumi Yokota, Petr Danek, Srdjan Grusanovic, Mateusz Chiliński, Dariusz Plewczynski, Jakub Rohlena, Hideyo Hirai, Katerina Rohlenova, Meritxell Alberich Jorda
Journal: Blood (2023)
Bleeding Risk Factors in Thrombocytopenic Patients with Hematologic Malignancies
Authors: Jacqueline Poston, Siobhan Brown, Amy S Ginsburg, Anton Ilich, Heather Herren, Nahed El Kassar, Christopher Edward Jensen, Darrell J Triulzi, Nigel S. Key, Susanne May, Terry B Gernsheimer
Journal: Blood (2023)
Long-Term Outcomes after Unrelated Marrow Transplantation for Aplastic Anemia with Optimized Cyclophosphamide Dose (BMT CTN 0301)
Authors: Mary Eapen, Joseph Antin, Jakub Tolar, Sally Arai, Mitchell Horwitz, Jainqun Kou, Eric Leifere, John M. McCarty, Ryotaro Nakamura, Michael A. Pulsipher, Mary M. Horowitz, H Joachim Deeg
Journal: Blood (2023)
Monitoring of Hemostatic Status and Treatment Response in Von Willebrand Disease Using a Microchip Flow Chamber Assay
Authors: Elena G Arias-Salgado, Paula Acuña, Elena Monzón Manzano, Monica Martin Salces, Maria Isabel Rivas Pollmar, Pilar Lopez Gotor, Nora Butta, Cedric R. Hermans, Víctor Jiménez-Yuste, Maria Teresa Álvarez-Roman
Journal: Blood (2023)
Is Allogeneic Hematopoietic Stem Cell Transplant (HCT) in First Remission Beneficial to Acute Myeloid Leukemia (AML) Patients with Isocitrate Dehydrogenase(IDH) Mutations?
Authors: Ayman Sayyed, Taehyung Simon Kim, Silvia Park, Jae-Sook Ahn, Aly Karsan, Marie-France Gagnon, Julie Bergeron, Hyeoung-Joon Kim, Heeje Kim, David Sanford, Andre C. Schuh, Dennis Dong Hwan Kim
Journal: Blood (2023)
Measurable Residual Disease Assessment in Patients with Acute Myeloid Leukemia Aged ≥60 Years Treated with a 10-Day Decitabine Schedule Versus Intensive Chemotherapy in the AML21 Study (NCT02172872)
Authors: Adriano Venditti, Michal Kicinski, Ernesta Audisio, Mario Luppi, Gianluca Gaidano, Robin Foà, Anna Candoni, Andrea Mengarelli, Attilio Olivieri, Annalisa Imovilli, Maurizio Musso, Paolo De Fabritiis, Eliana Zuffa, Nicola Cascavilla, Agostino Tafuri, Maria Ilaria Del Principe, Stefan Suciu, Anne Giraut, Stéphanie Antunes, Pierre W. Wijermans, Michael Lübbert, Geert A. Huls, Marco Vignetti, Francesco Buccisano
Journal: Blood (2023)
Risk of Infections in Multiple Myeloma in the Era of Novel Agents, a Population-Based Study Based on 8672 Multiple Myeloma Patients Diagnosed 2008-2021 from the Swedish Myeloma Registry
Authors: Cecilie Hveding Blimark, Kristina Carlson, Christopher Day, Sigrun Einarsdottir, Gunnar Juliusson, Moshtak Karma, Dorota Knut-Bojanowska, Gunnar Larfors, Ingemar Turesson, Mariana Villegas Scivetti, Ingigerdur Sverrisdottir
Journal: Blood (2023)
Efficacy and Safety of Less Frequent/Lower Intensity Dosing of Talquetamab in Patients with Relapsed/Refractory Multiple Myeloma: Results from the Phase 1/2 MonumenTAL-1 Study
Authors: Ajai Chari, Albert Oriol, Amrita Krishnan, Maria Del Carmen Martinez Chamorro, Luciano Costa, Maria Victoria Mateos, Monique C Minnema, Michela Campagna, Tara J Masterson, Brandi W Hilder, Jaszianne Tolbert, Thomas Renaud, M. Damiette Smit, Swarna Ramanjulu, Paula Rodríguez Otero
Journal: Blood (2023)
Matching-Adjusted Indirect Comparison (MAIC) of Efficacy and Safety of Lisocabtagene Maraleucel (liso-cel) and Mosunetuzumab for the Treatment (Tx) of Third Line or Later (3L+) Relapsed or Refractory (R/R) Follicular Lymphoma (FL)
Authors: Loretta J. Nastoupil, Ashley Bonner, Pearl Wang, Lamees Almuallem, Jigar Desai, Omotayo Fasan, Thalia Farazi, Jinender Kumar, Saurabh Dahiya
Journal: Blood (2023)
Risk Factors for CD19-Targeting CAR T Manufacturing Failure and Patient Outcomes: A Report from the UK National CAR T Panel
Authors: Vaishali Dulobdas, Amy A Kirkwood, Fabio Serpenti, Brijesh Gautama, Aikaterini Panapoulou, Sumantha Gabriel, Ram Malladi, Jessica Pealing, Denise Bonney, Emma Nicholson, Caroline Besley, Sara Ghorashian, Elizabeth Davies, Jackie Chappell, Anne Black, Tobias Menne, Maeve O'Reilly, Robin Sanderson, Sridhar Chaganti
Journal: Blood (2023)
Beyond Mitigating Immune-Related Adverse Events: Glucocorticoids Ameliorate Bispecific Antibody-Mediated T-Cell Exhaustion <i>I n Vitro</i>
Authors: Amelie Muth, Nora Philipp, Anetta Marcinek, Tobias Straub, Lis Winter, Gerulf Hänel, Daniel Nixdorf, Lisa Rohrbacher, Veit L. Buecklein, Marion Subklewe
Journal: Blood (2023)
Allogeneic Hematopoietic Stem Cell Transplantation with Treosulfan -Fludarabine and Busulfan-Fludarabine Conditioning Have Similar Efficacy in Patients ≥65 Years Old or Those with Comorbidities
Authors: Israel J. Henig, Ohad Geller, Dana Yehudai-Ofir, Baher Krayem, Avraham Frisch, Hazim Khatib, Tsila Zuckerman
Journal: Blood (2023)
Intensive Induction Chemotherapy (IC) Vs Hypomethylating Agents + Venetoclax (HMA/VEN) in <i>IDH1-</i> or <i>IDH2</i>-Mutant Newly Diagnosed Acute Myeloid Leukemia (AML) - a Multicenter Cohort Study
Authors: Jan Philipp Bewersdorf, Shai Shimony, Rory M. Shallis, Yiwen Liu, Eva Johanna Schaefer, Amer M. Zeidan, Aaron D. Goldberg, Eytan M. Stein, Guido Marcucci, R. Coleman Lindsley, Evan C. Chen, Jorge Ramos, Anthony Selwyn Stein, Daniel J. DeAngelo, Donna S. Neuberg, Richard M Stone, Brian J. Ball, Maximilian Stahl
Journal: Blood (2023)
Limited Utility of Mayo 2012 Cardiac Staging System for Risk Stratification of Patients with Advanced Cardiac AL Amyloidosis - Analysis of a Uniformly Treated Cohort of 1275 Patients
Authors: Jahanzaib Khwaja, Sriram Ravichandran, Joshua Bomsztyk, Oliver Charles Cohen, Darren Foard, Ana Martinez - Naharro, Lucia Venneri, Marianna Fontana, Philip N Hawkins, Julian Gillmore, Helen J Lachmann, Shameem Mahmood, Carol Whelan, Ashutosh D. Wechalekar
Journal: Blood (2023)
Intermittent Sargramostim Administration Expands Proliferating Naïve T Cells, Tregs, HLA-DR+ PD-L1+ Monocytes and Myeloid-Derived Suppressor Cells: Results from a Randomized Placebo-Controlled Clinical Trial of GM-CSF in Patients with Peripheral Artery Disease
Authors: Alireza Rahbar, Mohammad S. Hossain, Cynthia R. Giver, Shivang Desai, Yazan Haroun, Tanveer Kauser, Kiran Ejaz, Arshed A. Quyyumi, Edmund K. Waller
Journal: Blood (2023)
Pre- and Post-Treatment Immune Contexture Correlates with Long Term Response in Large B Cell Lymphoma Patients Treated with Axicabtagene Ciloleucel (axi-cel)
Authors: Mike Mattie, Melanie Grosso, Aurelie Auguste, Denis Arnaud, Frederick L. Locke, Sattva S. Neelapu, David B. Miklos, Caron A Jacobson, Lazaros J. Lekakis, Yi Lin, Armin Ghobadi, Jenny J. Kim, Jenny Nater, Rhine R. Shen, Jerome Galon
Journal: Blood (2023)
Treatment of Molecular Relapses in Pediatric AML Saves Toxicities Prior to Hematopoietic Stem Cell Transplantation (HSCT) - Results of AMoRe2017 Trial
Authors: Amelie Polutta, Dirk Reinhardt, Andre Baruchel, Henrik Hasle, Franco Locatelli, C. Michel Zwaan, Michael Frühwald, Silke Westphal, Michael Dworzak, Heidrun Boztug, Gabriele Escherich, Thomas Lehrnbecher, Bianca F. Goemans, Brigitte Strahm, Markus Schneider, Lina Hoffmeister, Katharina Waack
Journal: Blood (2023)
A Single Centre Cohort Study of Monitoring B Cell Populations in the Bone Marrow and Peripheral Blood Post Tisagenlecleucel Therapy of Relapsed/Refractory Acute Lymphoblastic Leukaemia
Authors: Sneha Fernandes, Archana Rauthan, Macarena Oporto Epuelas, Katherine Berry, Saskia Burridge, Charlotte Twigdon-Williams, Christopher Connor, Mark Davis, Kimberly Gilmour, Rebecca Thomas, Phil Ancliff, Jack Bartram, Robert Chiesa, Giovanna Lucchini, Vesna Pavasovic, Anupama Rao, Kanchan Rao, Sujith Samarasinghe, Juliana Silva, Ajay Vora, Persis Amrolia, Sara Ghorashian
Journal: Blood (2023)
Predictors of Outcomes with Venetoclax-Based Treatment in Patients with Progressive Disease or Intolerance after Covalent BTK Inhibitors
Authors: Laura Samples, Sirin Khajaviyan, Ryan C Lynch, Mehrdad Shakib-Azar, Christine Crider, Margie Fredericks, Hania Shakalia, Stephanie Louie, David G Maloney, Christina Poh, Brian G Till, Stephen D Smith, Ajay K Gopal, Chaitra S Ujjani, Mazyar Shadman
Journal: Blood (2023)
Myelodysplasia-Related Gene Mutations for NGS-Based MRD Assessment in Acute Myeloid Leukemia
Authors: Maximilian Bader, Arba Mahmuti, Jannika Leßmann, Henri C Hupe, Razif Gabdoulline, Martin Wichmann, Letizia Venturini, Michael Stadler, Wolfram Puppe, Walter Fiedler, Jürgen Krauter, Arne Trummer, Bernd Hertenstein, Matthias Eder, Arnold Ganser, Felicitas Thol, Michael Heuser, Rabea Mecklenbrauck
Journal: Blood (2023)
Palmitoylethanolamide Modulates Gait By Targeting Purkinje Cells in the Brain of Sickle Mice
Authors: Kristen Peterson, Kendall O'Daniel, Donovan Alexander Argueta, Mya Angela Arellano, Raghda T Fouda, Graham J Velasco, Natalie Garcia, Kalpna Gupta
Journal: Blood (2023)
The Cytogenetic and Molecular Testing Landscape in Patients with Newly Diagnosed Acute Myeloid Leukemia in Routine Clinical Practices in the United States
Authors: Kimo Bachiashvili, Shuko Harada, Esprit Ma, Achal Patel, Rongrong Wang, Archibong Yellow-Duke, Melissa Montez, Vivek Chopra, Cat N. Bui, Pankit Vachhani
Journal: Blood (2023)
Diagnostic Accuracy of a Fully Automated Method of Analysing MR Images for Evaluation of Liver Iron Concentration in a Population of Thalassemia Major Patients Following Curative Stem Cell Transplantation in Lebanon
Authors: Adlette Inati, Nada Sbeiti, Evelyne Khoriaty, Suzan Koussa, Ali T Taher, Therese Abi Nasr, Tim St Pierre
Journal: Blood (2023)
Clinical Outcomes of Noninhibitor Patients with Hemophilia a Switching from Prophylaxis with Factor VIII to Emicizumab: A Meta-Analysis of Real-World Evidence Studies
Authors: Miguel A. Escobar, Qi Angela Fan, Ali G Mokdad, Michael D. Tarantino, Benjamin Burgess, Emma Hawe, Maria Fernandez, Michael Bullano
Journal: Blood (2023)
Alterations in Immune Cell Composition during First-Line Therapy with Mosunetuzumab for Follicular or Marginal Zone Lymphoma
Authors: Adam J Olszewski, Thomas Ollila, Ari Pelcovits, Anna Dorota Chorzalska, John Morgan, Jessica McMahon, Stephen Donnelly, Scott F. Huntington, Matthew Matasar, John L. Reagan, Charles Milrod, Patrycja M. Dubielecka
Journal: Blood (2023)
Deciphering the Dynamics of the B-NHL Single-Cell Landscape during BTK Inhibition
Authors: Hosna Baniadam, Tobias Wertheimer, Stefanie Reisenauer, Odit Gutwein, Thi Huong Lan Do, Marcel Pohly, Ester Cannizzaro, Lukas Rindlisbacher, Stefanie Kreutmair, Susanne Unger, Can Ulutekin, Marijne Vermeer, Colin Sparano, Andreas Moor, Wolfgang Huber, Burkhard Becher, Thorsten Zenz
Journal: Blood (2023)
Long-Term Treatment with Fostamatinib in Japanese Patients with Primary Immune Thrombocytopenia: An Open-Label Extension Study Following a Phase 3 Placebo-Controlled, Double-Blind, Parallel-Group Study
Authors: Masataka Kuwana, Tomoki Ito, Shugo Kowata, Yoshihiro Hatta, Katsumichi Fujimaki, Kensuke Naito, Shingo Kurahashi, Toshiya Kagoo, Kazuki Tanimoto, Natsuko Shichiri, So Saotome, Esteban Masuda, Yoshiaki Tomiyama
Journal: Blood (2023)
Treatment Patterns and Outcomes for Patients with Newly Diagnosed Multiple Myeloma Post-Stem Cell Transplantation Who Received Lenalidomide As First Line Maintenance Therapy (PREAMBLE)
Authors: Ravi Vij, Suvina Amin, Jin Gu, Thomas S. Marshall, Susan Fish, Sujith Dhanasiri, Gabriela Hernandez, David Cella, Hartmut Goldschmidt, Karthik Ramasamy
Journal: Blood (2023)
The Potent Dihydroorotate Dehydrogenase Inhibitor, Hosu-53, Exhibits Compelling Monotherapy Efficacy in Multiple Myeloma and Augments CD47 Targeted Therapy
Authors: Gerard Hilinski, Blaise Stearns, Sandip Vibhute, Tiffany Hughes, Susheela Tridandapani, Megan E. Johnstone, Thomas E. Goodwin, Jeffrey Patrick, Chad E. Bennett, Don Benson, John C. Byrd, Ola A. Elgamal, Erin K. Hertlein
Journal: Blood (2023)
Assessment of Ultra-Deep Mass Spectrometry Based Proteomics Compared to Flow Cytometry and RNA-Based Methods for the Discovery and Validation of Therapeutic Targets in Immune Cells
Authors: Yu-Wah Au, Gemma Rigter, Wingyan Yu, David Satijn, Martin Mehnert, Amaury Lachaud, Jakob Vowinckel, Joost Neijssen, Helene Bon
Journal: Blood (2023)
Polyamines Are Required for AML LSC Function through Their Role in Regulating eIF5A Dependent Protein Synthesis
Authors: Vincent Rondeau, Rachel Culp-Hill, Julie A Reisz, Duhan Yendi, Aarushi Gupta, Jacob Berman, Cristiana O'Brien, Tianyi Ling, Aleksandra Bourdine, Mary Shi, Jonathan St-Germain, Soheil Jahangiri, Anastasia N. Tikhonova, Andrea Arruda, Mark D. Minden, Brian Raught, Angelo D'Alessandro, Courtney L Jones
Journal: Blood (2023)
A Phase 1 Trial of OPB-111077 in Combination with Bendamustine (B) and Rituximab (R) in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL): Preliminary Results of Dose-Escalation Stage
Authors: Tomomi Toubai, Junya Kuroda, Youko Suehiro, Yuko Mishima, Kazutaka Sunami, Koji Kato, Nobuhiko Uoshima, Takahiro Kumode, Ai Ota, Kaori Mitsuki, Daisuke Yokota, Yuri Sano, Yasuhito Terui
Journal: Blood (2023)
A Miniaturized, Rapid Technique for Measuring Red Blood Cell-Mediated Microcapillary Occlusion in HbAS, HbSC, and HbSS Sickle Cell Disease Genotypes
Authors: Solomon Oshabaheebwa, Christopher A. Delianides, Zoe Sekyonda, Yusang M. Bejarano Ley, Calvin Abonga, Vivien A Sheehan, Michael A. Suster, Pedram Mohseni, Umut A. Gurkan
Journal: Blood (2023)
Pyrimidine Starvation Is a Targetable Cancer Vulnerability: Mechanisms of Nucleotide Homeostasis
Authors: Jelena Milosevic, Johannes Elferich, Kashish Chetal, Mary Ayres, Varsha Gandhi, Ruslan Sadreyev, Nikolaus Grigorieff, Shobha Vasudevan, David Sykes
Journal: Blood (2023)
Extended Follow-up of ALPINE Randomized Phase 3 Study Confirms Sustained Superior Progression-Free Survival of Zanubrutinib Versus Ibrutinib for Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (R/R CLL/SLL)
Authors: Jennifer R. Brown, Barbara F. Eichhorst, Nicole Lamanna, Susan M. O'Brien, Constantine S. Tam, Luqui Qiu, Maciej Kaźmierczak, Wojciech Jurczak, Keshu Zhou, Martin Simkovic, Jiri Mayer, Amanda L. Gillespie-Twardy, Alessandra Ferrajoli, Peter S. Ganly, Robert Weinkove, Sebastian Grosicki, Andrzej Mital, Tadeusz Robak, Anders Osterborg, Habte A. Yimer, Megan (Der Yu) Wang, Tommi Salmi, Liping Wang, Jessica Li, Kenneth Wu, Aileen Cleary Cohen, Mazyar Shadman
Journal: Blood (2023)
Biophysical Characterization of the Thermodynamic Basis and Binding Orientation for Factor VIII Membrane Association
Authors: Nathan G Avery, Kenneth C Childers, Selena Lu, Patrick Korus, Justin McGlone, Mady Jacobs, Tera Richardson, Juliet McGill, Kayla Croney, Jordan Vaughan, James McCarty, P. Clint Spiegel
Journal: Blood (2023)
Mitophagy As a Novel Cell-Protective Mechanism Against Mitochondrial Ferroptosis in Acute Myeloid Leukemia
Authors: Hiroki Akiyama, Matthew Tcheng, Priyanka Sharma, Ran Zhao, Lauren B. Ostermann, Samar Yazdani, Arman Moayed, Zdzislaw Szulc, Natalia Oleinik, Po Yee Mak, Vivian Ruvolo, Bing Z. Carter, Besim Ogretmen, Gautam Borthakur, Aaron D. Schimmer, Michael Andreeff, Jo Ishizawa
Journal: Blood (2023)
Effect of New or Worsening Anemia on Clinical Outcomes in 2233 Patients with Myelofibrosis Treated with Ruxolitinib in the Expanded-Access Jump Study
Authors: Vikas Gupta, Paola Guglielmelli, JE Hamer-Maansson, Evan M. Braunstein, Haifa Kathrin Al-Ali
Journal: Blood (2023)
Clinical Outcomes of Patients Receiving 3 Versus 4 Doses of Methotrexate with Concomitant Anti-Thymocyte Globulin; A Single Center Experience
Authors: Kittika Poonsombudlert, Sarah L Mott, Brenda Miller, Hira Shaikh, Christopher Strouse, Jonathan Lochner, Umar Farooq, Margarida Magalhaes-Silverman
Journal: Blood (2023)
Score to Guide Donor Choice in Haploidentical Stem Cell Transplant Using Post-Transplant Cyclophosphamide for Patients with Acute Myeloid Leukemia: A Study from the Acute Leukemia Working Party of the EBMT
Authors: Jaime Sanz, Myriam Labopin, Didier Blaise, Anna Maria Raiola, Alessandro Busca, Jan Vydra, Johanna Tischer, Patrice Chevallier, Stefania Bramanti, Renato Fanin, Gerard Socié, Edouard Forcade, Nicolaus Kröger, Yener Koc, Maija Itäla-remes, Marco Zecca, Arnon Nagler, Eolia Brissot, Alexandros Spyridonidis, Ali Bazarbachi, Sebastian Giebel, Simona Piemontese, Mohamad Mohty, Fabio Ciceri
Journal: Blood (2023)
Selective Targeting of TP53-Y220C Mutant AML By PC14586 Results in TP53 Wild-Type Conformation and Synergistical Apoptosis Induction By Concomitant Inhibition of Xpo-1, MDM2, or Bcl-2
Authors: Bing Z. Carter, Po Yee Mak, Baozhen Ke, Yuki Nishida, Steffen Boettcher, Andrea Bedoy, Lauren B. Ostermann, Courtney D. DiNardo, Anna Puzio-Kuter, Arnold Levine, Michael Andreeff
Journal: Blood (2023)
Polycom Group Protein Mel18 Inhibits Hematopoietic Stem Cell Self-Renewal through Repressing the Expression of Genes Important for Cellular Senescence and Proliferation
Authors: Wenjie Cai, Sisi Chen, Xicheng Liu, Xintong Chen, Sergio Barajas, Shiyu Xiao, Hongxia Chen, Rongwen Xi, Zhonghua Gao, Feng Yue, Yan Liu
Journal: Blood (2023)
Transform-1: A Randomized, Double-Blind, Placebo-Controlled, Multicenter, International Phase 3 Study of Navitoclax in Combination with Ruxolitinib Versus Ruxolitinib Plus Placebo in Patients with Untreated Myelofibrosis
Authors: Naveen Pemmaraju, Adam J Mead, Tim CP Somervaille, James K McCloskey, Francesca Palandri, Steffen Koschmieder, David Lavie, Brian Leber, Su-Peng Yeh, Maria Teresa Gómez-Casares, Emanuele Ammatuna, Ho-Jin Shin, Keita Kirito, Eric Jourdan, Timothy Devos, Hun S Chuah, Atanas Radinoff, Andrija Bogdanovic, Rastislav Moskal, Qi Jiang, Avijeet S Chopra, Elektra Papadopoulos, Jalaja Potluri, Francesco Passamonti
Journal: Blood (2023)
Real-World Treatment Patterns, Overall Survival, Healthcare Resource Utilization, and Costs Among U.S. Elderly Patients with Mantle Cell Lymphoma (MCL) after Failure of Covalent Btki Treatment
Authors: Patrick Squires, Justin T. Puckett, Katherine Elizabeth Ryland, Sachin Kamal-Bahl, Monika Raut, Jalpa A. Doshi, Scott F. Huntington
Journal: Blood (2023)
Preliminary Results from a Multicenter Phase 2/3 Study of Next-Generation HbS Polymerization Inhibitor GBT021601 for the Treatment of Patients with Sickle Cell Disease
Authors: Santosh L. Saraf, Shehu Umar Abdullahi, Adeseye Michael Akinsete, Foluke A Fasola, Modupe Idowu, Sharon Pennington, William B Ershler, Marshall Patrick Stagg, Wai Chin, Eric Zimmerman, Adeyemi Adenola, Mira Patel Pochron, Eleanor A Lisbon
Journal: Blood (2023)
Similar Efficacy of Ibrutinib Arms across ALPINE and ELEVATE-RR Trials in Relapsed/Refractory Chronic Lymphocytic Leukemia: A Matching-Adjusted Indirect Comparison
Authors: Mazyar Shadman, Alessandra Tedeschi, Leyla Mohseninejad, Keri Yang, Nicole Lamanna, Sheng Xu, Aileen Cleary Cohen, Swetha Challagulla, Mei Xue, Rhys Williams, Susan M. O'Brien, Jennifer R. Brown, Constantine S. Tam
Journal: Blood (2023)