tbuckley/cabot-search huggingface dataset:
Depression and abnormal endocrinologic tests
Authors: J. S. Steinberg
Journal: JAMA (1981)

<h3>In Reply.—</h3> In the evaluation of patients with presumed endocrine disorders, the presence of active major depression may, by producing falsepositive results, make the standard neuroendocrine testing protocols less useful. What may be a false-positive result for endocrinologic purposes (once ruled out) provides a reliable true-positive result for the confirmation of a psychiatric diagnosis of major unipolar depression. Psychiatric patients with major depression must be carefully evaluated for Cushing's syndrome,<sup>1,2</sup>thyroid axis dysfunction,<sup>3</sup>as well as a long list of other endocrine, medical, and neurologic illnesses. Adrenal hyperfunction is common in patients with major depression. This hyperfunction is not due to emotional distress, hospitalization, or anxiety per se but appears to be a concomitant manifestation of major depression. These depressed patients do not demonstrate clinical evidence of Cushing's disease but have diurnal cortisol and adrenocorticotropic hormone secretory abnormalities, hypersecretion, and failure to demonstrate adequate suppression in response to
By how much does dietary salt reduction lower blood pressure? I--Analysis of observational data among populations.
Authors: M R Law, C D Frost, N J Wald
Journal: BMJ (1991)

OBJECTIVE--To estimate the quantitative relation between blood pressure and sodium intake. DESIGN--Data were analysed from published reports of blood pressure and sodium intake for 24 different communities (47 000 people) throughout the world. MAIN OUTCOME MEASURE--Difference in blood pressure for a 100 mmol/24 h difference in sodium intake. Allowance was made for differences in blood pressure between economically developed and undeveloped communities to minimise overestimation of the association through confounding with other determinants of blood pressure. RESULTS--Blood pressure was higher on average in the developed communities, but the association with sodium intake was similar in both types of community. A difference in sodium intake of 100 mmol/24 h was associated with an average difference in systolic blood pressure that ranged from 5 mm Hg at age 15-19 years to 10 mm Hg at age 60-69. The differences in diastolic blood pressure were about half as great. The standard deviation of blood pressure increased with sodium intake implying that the association of blood pressure with sodium intake in individuals was related to the initial blood pressure--the higher the blood pressure the greater the expected reduction in blood pressure for the same reduction in sodium intake. For example, at age 60-69 the estimated systolic blood pressure reduction in response to a 100 mmol/24 h reduction in sodium intake was on average 10 mm Hg but varied from 6 mm Hg for those on the fifth blood pressure centile to 15 mm Hg for those on the 95th centile. CONCLUSIONS--The association of blood pressure with sodium intake is substantially larger than is generally appreciated and increases with age and initial blood pressure.
Commentaire de travail de G. P. Aithal et al., pp. 725
Journal: Endoscopy (2007)

See also: EUS-guided tissue sampling: comparison of ”dual sampling” (Trucut biopsy plus FNA) with ”sequential sampling” (Trucut biopsy and then FNA as required)Endoscopy 2007; 39(08): 725-730DOI: 10.1055/s-2007-966400
Hepatobiliary/basic
Authors: A Par, M Paal, A G6gl, B Safrany, J Szekeres, T Ber6, J Gervain, Gy Brasch, Gy First
Journal: Gut (1994)

In order to clear the role of immune system in the pathogenesis of hepatitis C virus (HCV-positive liver disease, various cellular immune parameters have been studied in 24 patients with chronic hepatitis C. Lymphocyte subset dis- tribution in peripheral blood (total B, T, CD4+, CD8+, CD16+ cell counts), as well as mitogen-induced lymphoproliferative response and natural killer (NK) cell activity, furthermore HLA A, B, C and DR phenotypes were determined.In addition, we have searched for predictors of response to interferon (IFN) treatment.Results: there was no marked difference from the normal values con- cerning the lymphocyte subsets and mitogen-induced proliferative response, but the NK-cell activity proved to be significantly decreased (p 0.02) in HCV- patients.The prevalence of HLA B8 was 33% vs 15.2% of controls, HLA DR3 occurred in 42.8% vs 12%, HLA DR4 28.5% vs 12.7%, and HLA DQw2 50% vs 18.1%, respectively.The good response to IFN was not influenced by ei- ther the pretreatment lymphocyte findings or HLA phenotype.However, dur- ing the IFN treatment, both CD4+ and CD8+ cell counts were significantly lower in responders than others, at the end of the first month of therapy, while B cell count was significantly higher in these responders after three months.Recombinant IFN-alfa given at a dose of 3 MU thrice weekly resulted in a sus- tained complete remission in 28% of patients, and enhanced both mitogeninduced proliferative response and NK-cell activity in 50-75%.Predictors of response were: 1. a female predominance, 2. a shorter du- ration of the disease, (more exactly: HCV-positive blood transfusion given within 3 years), and 3. an absence of anti-HBc antibody in the sera.Conclusion: our findings suggest the importance of immune reaction and even possibly of HLA factors in the development of chronic hepatitis C. Fur- ther studies are needed to clarify the exact nature of immune mechanisms in this disease.
Incorrect Title
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ROYAL NAVY AND ARMY MEDICAL SERVICES
Authors: Mrs Barnett
Journal: BMJ (1906)

honorary secretary of the State Children's Association, now being circulated among its members, gives an interesting account of the progress made in getting rid of the practice of herding Poor-law children in worlchouse and barrack schools.Boards of Guardians in increasing numbers are providing for rate-supported children in scattered homes, thus giving them the advantage of something like home life and saving them from the taint of the workhouses and the risks of ophthalmia, ringworm, and other institutional scourge3.Good progress is being made in forming committees of voluntary workers to look after children boarded out in cottage homes, and the movement in favour of the formation of children's conrts is also progressing favourably.A Bill authorizing the official appointment of Probation officers and the release of youthful offenders on probation has been promised by the Home Secretary, and it is increasingly common throughout the country for arrangements to be made for trying youthful offenders apart from other prisoners.There are still, however, some 21,000 children in the workhouses, and in the work of getting them into more hopeful surround- ings the association requires assistance.
SERA FOR SNAKE BITES.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Urokinase-Streptokinase Embolism Trial
Journal: JAMA (1974)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Successful treatment of acquired factor VIII inhibitors with cyclosporin
Authors: Alan G. Brox, Horace Laryea, Marc Pelletier
Journal: American Journal of Hematology (1998)

The treatment of Factor VIII inhibitors remains controversial and no standard therapy exists. We describe in this report two consecutive patients with this inhibitor that responded to cyclosporin. Clinical improvement of the bleeding diathesis, a return to normal of the PTT, a decrease in the level of the inhibitor, and a return to normal of the factor VIII level followed use of this drug. We believe that cyclosporin is effective in the treatment of factor VIII inhibitors and deserves further investigation. Am. J. Hematol. 57:87–88, 1998. © 1998 Wiley-Liss, Inc.
FELLOWSHIP AND SUBSCRIPTION DUES FOR 1927
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Former patients give mental health clients a boost
Authors: R. Voelker
Journal: JAMA (1994)

AT THE Bronx Psychiatric Center in New York, peer pressure isn't necessarily discouraged. In fact, patients treated for schizophrenia, substance abuse, and other mental health conditions posted better outcomes after participating in a demonstration program that incorporated former psychiatric patients, known as "peer specialists," as members of case management teams. "This turned out to be a more interesting and complex story than most of us originally anticipated," said David Shern, PhD, director of evaluation and services research at the State of New York Office of Mental Health in Albany. Shern's colleagues presented their findings at the annual meeting of the American Public Health Association. <h3>Is Experience the Best Teacher?</h3> The program in New York is one in a growing number of studies attempting to gauge the impact of former patients working as adjuncts to mental health professionals, said Chip Felton, MSW, the study's principal data analyst and a research scientist
In Brief
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Estrogenicity of Resin-Based Composites and Sealants Used in Dentistry
Authors: Nicolas Olea, Rosa Pulgar, Pilar Perez, Fatima Olea-Serrano, Ana Rivas, Arantzazu Novillo-Fertrell, Vicente Pedraza, Ana M. Soto, Carlos Sonnenschein
Journal: Environmental Health Perspectives (1996)

We tested some resin-based composites used in dentistry for their estrogenic activity. A sealant based on bisphenol-A diglycidylether methacrylate (bis-GMA) increased cell yields, progesterone receptor expression, and pS2 secretion in human estrogen-target, serum-sensitive MCF7 breast cancer cells. Estrogenicity was due to bisphenol-A and bisphenol-A dimethacrylate, monomers found in the base paste of the dental sealant and identified by mass spectrometry. Samples of saliva from 18 subjects treated with 50 mg of a bis-GMA-based sealant applied on their molars were collected 1 hr before and after treatment. Bisphenol-A (range 90-931 micrograms) was identified only in saliva collected during a 1-hr period after treatment. The use of bis-GMA-based resins in dentistry, and particularly the use of sealants in children, appears to contribute to human exposure to xenoestrogens.
Surgical Pathology
Authors: E. A. Gall
Journal: JAMA (1964)

To the harried surgical pathology resident, viewing the day's collection of tissue sections, come recurrent moments of doubt and indecision. With "Ackerman" at hand much of this uncertainty should be dispelled. This is a highly practical volume, its textual matter concise and pithy, its abundant photographs well selected, clear, and revealing. The writing has an authoritative flavor although occasionally appearing somewhat arbitrary. The authors and their collaborators have broad experience in the day-to-day problems of the surgical pathology laboratory. This is reflected in a keen awareness of pitfalls related to mismanagement of histological technique and problems stemming from lack of valid clinical information. These and other matters are discussed in relaxed and homely fashion. A refreshing conversational style makes for ease of reading but occasionally some jargon appears (eg, "any specimen containing pathology," "congenital thyroid gland"). Excellent chapters on disorders of the skin, central nervous system, and the eye have
Commercial hair analysis: science or scam?
Authors: George Hickok
Journal: JAMA (1986)

<h3>To the Editor.—</h3> The publication of the recent article entitled "Commercial Hair Analysis: Science or Scam?" by Dr Stephen Barrett<sup>1</sup>surely constitutes a new low for<i>JAMA</i>. Space does not permit a point by point critique, but a few comments should be mentioned: Barrett ignores the literature published since 1974 showing that laboratories have learned how to manage or use to their advantage each of the seven items listed as problems.<sup>2</sup>In fact, laboratories for commercial hair analysis in existence in 1974 had overcome these problems at that time. Sixty percent of the business of Doctor's Data Inc, the oldest and largest laboratory for hair analysis, comes from physicians—many board certified in their specialty! Barrett infers that there is great discrepancy when two results from the same laboratory vary between normal and high, or normal and low. He does not explain that this can be by only one
DELAYED WOUND HEALING
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
UTILIDAD DE LA ECOENDOSCOPIA EN EL DIAGNÓSTICO DE LAS LESIONES QUÍSTICAS PANCREÁTICAS. EXPERIENCIA EN NUESTRO CENTRO
Authors: B Merino Rodríguez, C González Asanza, O Nogales Rincón, A Huerta Madrigal, A Pacheco, J Garrido, E Cos Arregui, P Menchén Fernández Pacheco
Journal: Endoscopy (2010)

Introducción: La ecoendoscopia con PAAF tiene una gran relevancia en el diagnóstico de las lesiones quísticas pancreáticas (LQP). Lesiones de compleja filiación y que cada vez son un hallazgo más frecuente en la práctica clínica por el empleo de mejores técnicas de imagen.
P1.13 Anaplastic Lymphoma Kinase (ALK) Gene Rearrangement in Children and Young Adults with Mesothelioma
Authors: I. Mian, Z. Abdullaev, B. Morrow, S. Gao, M. Mettienen, J. Wei, J. Khan, S. Pack, R. Hassan
Journal: Journal of Thoracic Oncology (2019)
Dispensing doctors
Authors: A J Morton-Jones, M A L Pringle
Journal: BMJ (1992)

Dispensing doctorsEDITOR, -David Roberts has grossly misinter- preted the statistics from the Prescription Pricing Authority in his letter on dispensing doctors.' Closer examination of the detail provided in the authority's annual report for 1990-1 shows that savings could be made if all dispensing was undertaken by pharmacists.
Effects of inhaled salbutamol in exercising non-asthmatic athletes
Authors: C Goubault, M-C Perault, E Leleu, S Bouquet, P Legros, B Vandel, A Denjean
Journal: Thorax (2001)

BACKGROUND Beta-2 agonists such as salbutamol are used, not only by asthmatic athletes to prevent exercise induced asthma, but also by non-asthmatic athletes as a potentially ergogenic agent. We have investigated whether inhaled salbutamol enhances endurance performance in non-asthmatic athletes. METHODS A prospective double blind, randomised, three way crossover design was used to study the effects of 200 μg and 800 μg inhaled salbutamol versus a placebo in 12 trained triathletes. The treatments were compared in three identical cycle ergometer sessions at 85% of the predetermined maximal oxygen uptake. Lung function, endurance time, metabolic parameters (glucose, potassium, lactate, free fatty acid, and glycerol), and psychomotor performance were evaluated. RESULTS Neither endurance time nor post-exercise bronchodilation were significantly different between the treatments. Metabolic parameters were affected by exercise but not by treatment. CONCLUSIONS Inhaled salbutamol, even in a high dose, did not have a significant effect on endurance performance in non-asthmatic athletes, although the bronchodilating effect of the drug at the beginning of exercise may have improved respiratory adaptation. Our results do not preclude an ergogenic effect of β 2 agonists given by other routes or for a longer period.
Rigid trachea.
Authors: A. Sakula
Journal: BMJ (1968)

approach, his curve was 90'.Thus, three spines out of a group of 60 with a similar condition were distorted by a hiatus hernia box, and all three are among the small pro- portion (7 out of 60) who failed to resolve without demonstrable cause within 18 months.It is possible that prolonged " sitting " in the box acted against resolution of the curve.Whilst treating hiatus hernia in an infant one has no attractive alternative to using the box, but its use in normal children, which is becoming increasingly popular, should be watched.-Iam, etc.,
Bedside Cardiology
Authors: Raymond Harris
Journal: JAMA (1970)

<i>Bedside Cardiology</i>is an unconventional but interesting volume intended to teach elementary and advanced aspects of cardiologic physical diagnosis to the medical student, house staff officer, and practicing physicians who may or may not have available special equipment, such as a phonocardiograph and pulse amplifier. What makes this attractively designed book unorthodox is its question-answer format, a variant of programmed learning, but not true programmed learning which requires first the presentation of new information and then pertinent questions and appropriate responses. This book often presupposes knowledge on the part of the reader and proceeds to ask questions without any previous explanation or information on the subject. The unmotivated learner or the busy practitioner may find this text too time-consuming or inadequate for his immediate needs. However, this question-answer method is an excellent teaching device and challenging at the more advanced levels of training. The organization and content of the book
Advanced liver fibrosis predicts poor cardiovascular outcomes in patients with type 2 diabetes
Authors: Ho Soo Chun, Hye Yeon Chon, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Seung Up Kim
Journal: Journal of Hepatology (2020)