tbuckley/cabot-search huggingface dataset:
Physical Fitness Predicts Survival in Men with Type 2 Diabetes
Journal: Annals of Internal Medicine (2000)

Summaries for Patients18 April 2000Physical Fitness Predicts Survival in Men with Type 2 DiabetesAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-8-200004180-00035 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Type 2 diabetes mellitus, also known as adult-onset diabetes, is a common disease that interferes with the body's ability to store foods, resulting in high blood levels of sugar. Over time, high blood sugar levels can lead to such complications as blindness, kidney failure, and heart disease. Exercise helps to control blood sugar, lower blood pressure and cholesterol, and prevent weight gain. It is not known, however, whether physical fitness actually improves survival for patients with type 2 diabetes.Why did the researchers do this particular study?To ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled "Low Cardiorespiratory Fitness and Physical Inactivity as Predictors of Mortality in Men with Type 2 Diabetes.". It is in the 18 April 2000 issue of Annals of Internal Medicine (volume 132, pages 605-611). The authors are M. Wei, L.W. Gibbons, J.B. Kampert, M.Z. Nichaman, and S.N. Blair.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoLow Cardiorespiratory Fitness and Physical Inactivity as Predictors of Mortality in Men with Type 2 Diabetes Ming Wei , Larry W. Gibbons , James B. Kampert , Milton Z. Nichaman , and Steven N. Blair Metrics Cited byExercise capacity is associated with hospital readmission among patients with diabetesMechanisms of Aerobic Exercise Impairment in Diabetes: A Narrative ReviewModerate physical activity reduces 10-year diabetes incidence: the mediating role of oxidative stress biomarkers 18 April 2000Volume 132, Issue 8Page: 605KeywordsBlood sugarExerciseHabitsInsulinMortalityPhysical fitnessRenal diseasesRenal failureType 2 diabetesWeight gain ePublished: 15 August 2000 Issue Published: 18 April 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.Loading ...
Progressive Therapeutics
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Invasive pulmonary aspergillosis associated with influenza
Authors: J. J. Fischer
Journal: JAMA (1979)

Fatal invasive pulmonary aspergillosis may follow viral influenza infections. Two cases with verified influenza A infection were followed by fatal necrotizing pneumonia due to<i>Aspergillus fumigatus</i>. Both patients demonstrated cutaneous anergy and lymphocytopenia. Influenza and perhaps other viruses that depress T-cell function may result in increased susceptibility to infections in which T cells are important in host defenses. (<i>JAMA</i>241:1493-1494, 1979)
Regulation and Patterns of Endogenous and Exogenous Gene Expression during Differentiation of Embryonal Carcinoma Cells
Authors: Simonetta Astigiano, Michael I. Sherman, Patricio Abarzua
Journal: Environmental Health Perspectives (1989)

Embryonal carcinoma (EC) cells offer an interesting model system for evaluating differentiation because the cells are pluripotent, thus resembling germ cells and embryonic stem cells, and because a number of agents have been defined that are capable of promoting the differentiation of these cells. This chapter examines how EC cells might be triggered to differentiate, with emphasis on retinoic acid because this compound is a potent, naturally occurring inducer that has been studied extensively in this system. The nature of alterations in gene expression during EC cell differentiation is reviewed from the perspective of evaluating whether these changes are likely to be responsible for, or a result of, the differentiation event. Finally, we consider in molecular terms why EC cells, but not their differentiated derivatives, are refractory to the expression of many viral genomes following infection. Based upon these studies, we propose that fundamental changes in gene expression that are observed when differentiation is triggered in EC cells are likely to be due to the disappearance or neutralization of strong repressor elements.
ANTISEPSIS FOR THE HANDS.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE BRAIN AND SPINAL CORD IN HEREDITARY ATAXIA.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INTERCAPILLARY GLOMERULOSCLEROSIS
Authors: CARL L.  MAUSER, ALBERT H.  ROWE, PAUL P. E.  MICHAEL
Journal: Annals of Internal Medicine (1942)

Article1 July 1942INTERCAPILLARY GLOMERULOSCLEROSISCARL L. MAUSER, M.D., ALBERT H. ROWE, M.D., F.A.C.P., PAUL P. E. MICHAEL, M.D.CARL L. MAUSER, M.D.Search for more papers by this author, ALBERT H. ROWE, M.D., F.A.C.P.Search for more papers by this author, PAUL P. E. MICHAEL, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-17-1-101 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThis syndrome of diabetes, hypertension and nephrosis was first described in 1936 by Kimmelstiel and Wilson.3They stressed the unusual and consistent pathological changes found in the kidneys, namely, degenerative changes in the walls of the capillaries, arterioles and vasa afferentia of the glomerular tufts. These authors reported eight cases with clinical and pathological findings. More recently Anson2reported six similar cases. Newburger and Peters,1in 1939, reviewed the two former papers and presented autopsy protocols of four cases and five cases in which the pathological renal lesions were suspected. A comprehensive analysis of the clinical, laboratory and pathological findings...Bibliography1. NEWBURGERPETERS RAJP: Intercapillary glomerulosclerosis, Arch. Int. Med., 1939, lxiv, 1252-1264. CrossrefGoogle Scholar2. ANSON LJ: Intercapillary glomerulosclerosis, South. Med. Jr., 1938, xxxi, 1272-1275. CrossrefGoogle Scholar3. KIMMELSTIELWILSON PC: Intercapillary lesions in the glomeruli of the kidney, Am. Jr. Path., 1936, xii, 83-98. Google Scholar4. DEROWALTSCHULESCHLESINGER HAMDMJ: The syndrome of diabetes mellitus, hypertension and nephrosis, New England Jr. Med., 1939, ccxxi, 1012-1015. CrossrefGoogle Scholar5. Diabetes mellitus; acute intercapillary glomerulonephritis (Cabot case 26272), New England Jr. Med., 1940, ccxxiii, 32-36. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Oakland, California*Received for publication March 3, 1941. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDiabetic Kidney Disease: Past and PresentA Historical Overview of Diabetic NephropathyA history of diabetes mellitus or how a disease of the kidneys evolved into a kidney diseaseIntercapillary GlomerulosclerosisIntercapillary glomerulosclerosis 1 July 1942Volume 17, Issue 1Page: 101-105KeywordsArteriolesAutopsyCapillariesClinical laboratoriesHypertensionKidneysLesions ePublished: 1 December 2008 Issue Published: 1 July 1942 PDF downloadLoading ...
Physiology of Adolescence
Authors: Felix P. Heald, Mary Daugela, Philip Brunschuyler
Journal: New England Journal of Medicine (1963)

CardiovascularPulseThere are many reported studies of pulse rate during the period of growth, but only representative ones are chosen to illustrate the apparent changes that occur in adolescence.120 121 122 123 Comparative analysis from the studies reported over the past fifty years is difficult since the pulse was determined under basal conditions in some121 , 122 and random measurements were made in others.123 Rather than dissect the reasons for differences in the various data it would be more profitable to note the trends in pulse rate.It is clear that the pulse rate drops from a high of 135 to 140 beats per . . .
An Embedded ("Lost") Contact Lens
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A novel FXR agonist EDP-297 exerts anti-inflammatory and hepatoprotective effects in human liver 3D microtissues and rodent NASH and liver injury models
Authors: Mary Chau, Manuel Roqueta-Rivera, Guoqiang Wang, Kelsey Garlick, Bindu Ramachandran, Kevin Mongeon, Nadya Bryan, Yat Sun Or, Bryan Goodwin
Journal: Journal of Hepatology (2020)
Health insurance and mortality. Evidence from a national cohort
Authors: P. Franks
Journal: JAMA (1993)

<h3>Objective.</h3> —To examine the relationship between lacking health insurance and the risk of subsequent mortality. <h3>Design.</h3> —Adults older than 25 years who reported they were uninsured or privately insured in the first National Health and Nutrition Examination Survey, a representative cohort of the US population, were followed prospectively from initial interview in 1971 through 1975 until 1987. <h3>Participants.</h3> —Complete baseline and follow-up information was obtained on 4694 (91%) persons of the 5161 who reported not receiving publicly funded insurance at baseline. <h3>Main Outcome Measure.</h3> —The relationship between insurance status and subsequent mortality was examined using Cox proportional hazards survival analysis. The analysis adjusted for gender, race, and baseline age, education, income, employment status, the presence of morbidity on examination, self-rated health, smoking status, leisure exercise, alcohol consumption, and obesity. The effects of interactions between insurance and all other baseline variables were also examined. <h3>Results.</h3> —By the end of the follow-up period, 9.6% of the insured and 18.4% of the uninsured had died. After adjustment for all other baseline variables, the hazard ratio for lacking insurance was 1.25 (95% confidence interval [Cl], 1.00 to 1.55). The effect of insurance on mortality was comparable to that of education, income, and self-rated health. There were no statistically significant (<i>P</i>&lt;.05) interactions. <h3>Conclusions.</h3> —Lacking health insurance is associated with an increased risk of subsequent mortality, an effect that is evident in all sociodemographic health insurance and mortality groups examined. (<i>JAMA</i>. 1993;270:737-741)
Eleventh Annual Report of the State Board of Health of Ohio for the year ending Oct. 31,1896.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical ethics: Code of Medical Ethics: Current Opinions With Annotations
Authors: A. L. Caplan
Journal: JAMA (1995)

It is time to give some credit where credit has for some time been wanting. For many, many years the last place anyone with a serious interest in the ethics of health care would be tempted to look for weighty moral analysis was the Code of Medical Ethics of the American Medical Association. Nothing in the Code made it into standard anthologies of bioethics. Almost no scholarly journals, including this one, would even bother to review the document. Up until 1955 the AMA Code had far more to do with matters of etiquette and professional comportment than with substantive matters of morality. It was not until 1980 that the Judicial Council of the AMA, today the Council on Ethical and Judicial Affairs, issued a revision of the AMA Principles of Medical Ethics that went beyond the norms that ought to be followed by physicians in private practice into the much
INADEQUACIES OF ARBITRARY MILK STANDARDS IN ENGLAND—THE "APPEAL TO THE COW."
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Measurement of Cytosolic Calcium Using 19 F NMR
Authors: Elizabeth Murphy, Louis Levy, Bore Raju, Charles Steenbergen, John T. Gerig, Phirtu Singh, Robert E. London
Journal: Environmental Health Perspectives (1990)

Fluorine-19 nuclear magnetic resonance (NMR) studies of cells and perfused organs loaded with fluorinated ion chelators represent a new approach to determining cytosolic free calcium levels in 8itU.The molecular basis for this approach and the relative advantages and disadvantages of the NMR technique are discussed in this paper.Results obtained on perfused normoxic and ischemic rat hearts are presented, indicating that ischemia is associated with an elevation in the level of cytosolic free calcium before the onset of irreversible cell injury.The results are therefore consistent with this elevation playing a causative role in the mediation of myocardial cell injury resulting from ischemia.
Addendum to “Prospective study of the G20210A polymorphism in the prothrombin gene, plasma prothrombin concentration, and incidence of venous thromboembolism”
Authors: Aaron R. Folsom
Journal: American Journal of Hematology (2007)

Copper Deficiency and DietTo the Editor: Harless et al. [1] reported two women with copper deficiency of unclear etiology whose deficiency quickly resolved after supplementation with copper gluconate.They suggested that consumption of 100 oz daily of soft drinks containing sucrose or fructose may have contributed to the problem because these simple sugars have been shown to disrupt copper utilization in animal experiments.A diet low in copper also may have been contributory.The Western diet often is low in copper [2], according to pooled data of more than 900 diets analyzed chemically and summarized in several articles.Recently, 62 and 36% of diets of 80 randomly selected adults in Baltimore, MD [3], were below the recommended dietary allowance (0.9 mg/day) and the estimated average requirement for adults (0.7 mg/day).The estimated average requirement is the median of a distribution of requirements; it applies only to apparently healthy people.Although soft drinks may have increased the copper requirements of the women, it seems unlikely that with body mass indices of 17 and 21 they had eaten sufficient copper from food when drinking 1400 kcal of Mountain Dew, or equivalent, daily.Recovery in a month from 2 mg copper gluconate daily (14.0%copper) yielding only 40% of the estimated average requirement is remarkable.
Detection of circulating heart-reactive antibody in human heart transplants
Authors: R. J. Ellis
Journal: JAMA (1970)

Immunofluorescent heart-reactive antibody was demonstrated in serum samples from three patients with cardiac transplants, one of whom is herewith presented in detail. The presence of this antibody correlated well with subsequent episodes of cardiac rejection. Increasing doses of immunosuppressive therapy had a direct effect on the disappearance of the circulating antibody from the serum samples of these patients. Up to the present, all signs and tests for cardiac rejection have relied upon the detection of the signs and effects of cardiac dysfunction, which of course means that significant damage has already occurred. Assay of heart-reactive antibody may be an early and sensitive indicator of cardiac rejection in patients with cardiac allografts.