tbuckley/cabot-search huggingface dataset:
Validation of Risk Stratification for Cardiac Events in Pregnant Women With Valvular Heart Disease
Authors: Swaraj Nandini Pande, J. Yavana Suriya, Sachit Ganapathy, Ajith Ananthakrishna Pillai, Santhosh Satheesh, Nivedita Mondal, K.T. Harichandra Kumar, Candice Silversides, Samuel C. Siu, Rohan D’Souza, Anish Keepanasseril
Journal: Journal of the American College of Cardiology (2023)
Outcomes After Hybrid Palliation for Infants With Critical Left Heart Obstruction
Authors: Madison B Argo, David J Barron, Pirooz Eghtesady, Can Yerebakan, Williams M DeCampli, Bahaaldin Alsoufi, Osami Honjo, Jeffrey P Jacobs, Tharini Paramananthan, Maha Rahman, Linda M Lambert, Anusha Jegatheeswaran, Sergio A Carrillo, S Adil Husain, Karthik Ramakrishnan, Christopher A Caldarone, Tara Karamlou, Jennifer Nelson, Chelsea Mannie, Jennifer C Romano, Joseph W Turek, Eugene H Blackstone, Mark E Galantowicz, James K Kirklin, Michael E Mitchell, Brian W McCrindle
Journal: Journal of the American College of Cardiology (2023)
Expanding the Paradigm for Cardiovascular Palliative Care
Authors: Sarah Godfrey, James N. Kirkpatrick, Daniel B. Kramer, Melanie S. Sulistio
Journal: Circulation (2023)

Cardiovascular disease (CVD) is the leading cause of death worldwide. Despite medical advances, patients with CVD experience high morbidity and mortality rates, affecting their quality of life and death. Among CVD conditions, palliative care has been studied mostly in patients with heart failure, where palliative care interventions have been associated with improvements in patient-centered outcomes, including quality of life, end-of-life care, and health care use. Although palliative care is now incorporated into the American Heart Association/American College of Cardiology/Heart Failure Society of America guidelines for heart failure, the role of palliative care for non-heart failure CVD remains uncertain. Across all causes of CVD, palliative care can play an important role in all domains of CVD care from initial diagnosis to terminal care. In addition to general cardiovascular palliative care practices applicable to all areas, disease-specific palliative care needs may warrant individualized palliative care models. In this review, we discuss the role of cardiovascular palliative care for ischemic heart disease, valvular disease, arrhythmias, peripheral artery disease, and adult congenital heart disease. Although there are multiple barriers to cardiovascular palliative care, we recommend a framework for studying and developing cardiovascular palliative care models to improve patient-centered goal-concordant care for this underserved patient population.
Systematic profiling of conditional pathway activation identifies context-dependent synthetic lethalities
Authors: Liang Chang, Nancy Y Jung, Adel Atari, Diego J Rodriguez, Devishi Kesar, Tian-Yu Song, Matthew G Rees, Melissa Ronan, Ruitong Li, Paloma Ruiz, Saireudee Chaturantabut, Takahiro Ito, Laurens M van Tienen, Yuen-Yi Tseng, Jennifer A Roth, William R Sellers
Journal: Nature Genetics (2023)
APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
Authors: Zhuoran Yin, Neta Rosenzweig, Kilian L. Kleemann, Xiaoming Zhang, Wesley Brandão, Milica A. Margeta, Caitlin Schroeder, Kisha N. Sivanathan, Sebastian Silveira, Christian Gauthier, Dania Mallah, Kristen M. Pitts, Ana Durao, Shawn Herron, Hannah Shorey, Yiran Cheng, Jen-Li Barry, Rajesh K. Krishnan, Sam Wakelin, Jared Rhee, Anthony Yung, Michael Aronchik, Chao Wang, Nimansha Jain, Xin Bao, Emma Gerrits, Nieske Brouwer, Amy Deik, Daniel G. Tenen, Tsuneya Ikezu, Nicolas G. Santander, Gabriel L. McKinsey, Caroline Baufeld, Dean Sheppard, Susanne Krasemann, Roni Nowarski, Bart J. L. Eggen, Clary Clish, Rudolph E. Tanzi, Charlotte Madore, Thomas D. Arnold, David M. Holtzman, Oleg Butovsky
Journal: Nature Immunology (2023)
A new method for multiancestry polygenic prediction improves performance across diverse populations
Authors: Haoyu Zhang, Jianan Zhan, Jin Jin, Jingning Zhang, Wenxuan Lu, Ruzhang Zhao, Thomas U. Ahearn, Zhi Yu, Jared O’Connell, Yunxuan Jiang, Tony Chen, Dayne Okuhara, Stella Aslibekyan, Adam Auton, Elizabeth Babalola, Robert K. Bell, Jessica Bielenberg, Katarzyna Bryc, Emily Bullis, Daniella Coker, Gabriel Cuellar Partida, Devika Dhamija, Sayantan Das, Sarah L. Elson, Nicholas Eriksson, Teresa Filshtein, Alison Fitch, Kipper Fletez-Brant, Pierre Fontanillas, Will Freyman, Julie M. Granka, Karl Heilbron, Alejandro Hernandez, Barry Hicks, David A. Hinds, Ethan M. Jewett, Katelyn Kukar, Alan Kwong, Keng-Han Lin, Bianca A. Llamas, Maya Lowe, Jey C. McCreight, Matthew H. McIntyre, Steven J. Micheletti, Meghan E. Moreno, Priyanka Nandakumar, Dominique T. Nguyen, Elizabeth S. Noblin, Aaron A. Petrakovitz, G. David Poznik, Alexandra Reynoso, Morgan Schumacher, Anjali J. Shastri, Janie F. Shelton, Jingchunzi Shi, Suyash Shringarpure, Qiaojuan Jane Su, Susana A. Tat, Christophe Toukam Tchakouté, Vinh Tran, Joyce Y. Tung, Xin Wang, Wei Wang, Catherine H. Weldon, Peter Wilton, Corinna D. Wong, Montserrat Garcia-Closas, Xihong Lin, Bertram L. Koelsch, Nilanjan Chatterjee
Journal: Nature Genetics (2023)
From alternative conceptions of honesty to alternative facts in communications by US politicians
Authors: Jana Lasser, Segun T. Aroyehun, Fabio Carrella, Almog Simchon, David Garcia, Stephan Lewandowsky
Journal: Nature Human Behaviour (2023)

Abstract The spread of online misinformation on social media is increasingly perceived as a problem for societal cohesion and democracy. The role of political leaders in this process has attracted less research attention, even though politicians who ‘speak their mind’ are perceived by segments of the public as authentic and honest even if their statements are unsupported by evidence. By analysing communications by members of the US Congress on Twitter between 2011 and 2022, we show that politicians’ conception of honesty has undergone a distinct shift, with authentic belief speaking that may be decoupled from evidence becoming more prominent and more differentiated from explicitly evidence-based fact speaking. We show that for Republicans—but not Democrats—an increase in belief speaking of 10% is associated with a decrease of 12.8 points of quality (NewsGuard scoring system) in the sources shared in a tweet. In contrast, an increase in fact-speaking language is associated with an increase in quality of sources for both parties. Our study is observational and cannot support causal inferences. However, our results are consistent with the hypothesis that the current dissemination of misinformation in political discourse is linked to an alternative understanding of truth and honesty that emphasizes invocation of subjective belief at the expense of reliance on evidence.
Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn’s disease
Authors: Gabriela Rios Martini, Ekaterina Tikhonova, Elisa Rosati, Meghan Bialt DeCelie, Laura Katharina Sievers, Florian Tran, Matthias Lessing, Arne Bergfeld, Sophia Hinz, Susanna Nikolaus, Julia Kümpers, Anna Matysiak, Philipp Hofmann, Carina Saggau, Stephan Schneiders, Ann-Kristin Kamps, Gunnar Jacobs, Wolfgang Lieb, Jochen Maul, Britta Siegmund, Barbara Seegers, Holger Hinrichsen, Hans-Heinrich Oberg, Daniela Wesch, Stefan Bereswill, Markus M. Heimesaat, Jan Rupp, Olaf Kniemeyer, Axel A. Brakhage, Sascha Brunke, Bernhard Hube, Konrad Aden, Andre Franke, Iliyan D. Iliev, Alexander Scheffold, Stefan Schreiber, Petra Bacher
Journal: Nature Medicine (2023)

Abstract Aberrant CD4 + T cell reactivity against intestinal microorganisms is considered to drive mucosal inflammation in inflammatory bowel diseases. The disease-relevant microbial species and the corresponding microorganism-specific, pathogenic T cell phenotypes remain largely unknown. In the present study, we identified common gut commensal and food-derived yeasts, as direct activators of altered CD4 + T cell reactions in patients with Crohn’s disease (CD). Yeast-responsive CD4 + T cells in CD display a cytotoxic T helper cell (T H 1 cell) phenotype and show selective expansion of T cell clones that are highly cross-reactive to several commensal, as well as food-derived, fungal species. This indicates cross-reactive T cell selection by repeated encounter with conserved fungal antigens in the context of chronic intestinal disease. Our results highlighted a role of yeasts as drivers of aberrant CD4 + T cell reactivity in patients with CD and suggest that both gut-resident fungal commensals and daily dietary intake of yeasts might contribute to chronic activation of inflammatory CD4 + T cell responses in patients with CD.
Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan
Authors: Carolien E van de Sandt, Thi H O Nguyen, Nicholas A Gherardin, Jeremy Chase Crawford, Jerome Samir, Anastasia A Minervina, Mikhail V Pogorelyy, Simone Rizzetto, Christopher Szeto, Jasveen Kaur, Nicole Ranson, Sabrina Sonda, Alice Harper, Samuel J Redmond, Hayley A McQuilten, Tejas Menon, Sneha Sant, Xiaoxiao Jia, Kate Pedrina, Theo Karapanagiotidis, Natalie Cain, Suellen Nicholson, Zhenjun Chen, Ratana Lim, E Bridie Clemens, Auda Eltahla, Nicole L La Gruta, Jane Crowe, Martha Lappas, Jamie Rossjohn, Dale I Godfrey, Paul G Thomas, Stephanie Gras, Katie L Flanagan, Fabio Luciani, Katherine Kedzierska
Journal: Nature Immunology (2023)

Abstract CD8 + T cells provide robust antiviral immunity, but how epitope-specific T cells evolve across the human lifespan is unclear. Here we defined CD8 + T cell immunity directed at the prominent influenza epitope HLA-A*02:01-M1 58–66 (A2/M1 58 ) across four age groups at phenotypic, transcriptomic, clonal and functional levels. We identify a linear differentiation trajectory from newborns to children then adults, followed by divergence and a clonal reset in older adults. Gene profiles in older adults closely resemble those of newborns and children, despite being clonally distinct. Only child-derived and adult-derived A2/M1 58 + CD8 + T cells had the potential to differentiate into highly cytotoxic epitope-specific CD8 + T cells, which was linked to highly functional public T cell receptor (TCR)αβ signatures. Suboptimal TCRαβ signatures in older adults led to less proliferation, polyfunctionality, avidity and recognition of peptide mutants, although displayed no signs of exhaustion. These data suggest that priming T cells at different stages of life might greatly affect CD8 + T cell responses toward viral infections.
APOEε4 potentiates amyloid β effects on longitudinal tau pathology
Authors: João Pedro Ferrari-Souza, Bruna Bellaver, Pâmela C L Ferreira, Andréa L Benedet, Guilherme Povala, Firoza Z Lussier, Douglas T Leffa, Joseph Therriault, Cécile Tissot, Carolina Soares, Yi-Ting Wang, Mira Chamoun, Stijn Servaes, Arthur C Macedo, Marie Vermeiren, Gleb Bezgin, Min Su Kang, Jenna Stevenson, Nesrine Rahmouni, Vanessa Pallen, Nina Margherita Poltronetti, Ann Cohen, Oscar L Lopez, William E Klunk, Jean-Paul Soucy, Serge Gauthier, Diogo O Souza, Gallen Triana-Baltzer, Ziad S Saad, Hartmuth C Kolb, Thomas K Karikari, Victor L Villemagne, Dana L Tudorascu, Nicholas J Ashton, Henrik Zetterberg, Kaj Blennow, Eduardo R Zimmer, Pedro Rosa-Neto, Tharick A Pascoal
Journal: Nature Aging (2023)
42857 A Study of Factors Affecting Sun-Protective Behavior Change after Surgical Treatment of Keratinocyte Carcinoma
Authors: Melika Marani, Divya Manoharan, Davies Gage, Luke Zhao, Shirley Lin, Sumrah Jilani, Jenny Carpenter, Chi Trinh, Elise Ng, Kristin Bibee, Jeffrey Scott
Journal: Journal of the American Academy of Dermatology (2023)
42188 A Study Evaluating the Safety and Effectiveness of Hyaluronic Acid Filler HARES for Correction of Infraorbital Hollows (IOH, Tear Trough Study)
Authors: Melanie D. Palm, Brian Biesman, Brian Biesman, Jeremy B. Green, Rosalyn George, Carolyn Jacob, Jason D. Bloom, Derek Jones, Lisa Grunebaum, Kenneth Beer, Young Cho, John Joseph
Journal: Journal of the American Academy of Dermatology (2023)
42979 Abortive hemangiomas: a morphological study of 35 cases
Authors: Leopoldo Fernández Domper, Manuel Ballesteros Redondo, Enrico Giorgio Morales Tedone, Andrea Bernabeu Aicart, Esmeralda Silva Diaz, Jose Maria Martin Hernández, Angeles Revert Fernández
Journal: Journal of the American Academy of Dermatology (2023)
42838 A Study of Factors Affecting Time to Definitive Surgery for Keratinocyte Carcinoma
Authors: Melika Marani, Divya Manoharan, Davies Gage, Luke Zhao, Shirley Lin, Sumrah Jilani, Jenny Carpenter, Chi Trinh, Elise Ng, Kristin Bibee, Jeffrey Scott
Journal: Journal of the American Academy of Dermatology (2023)
44042 Abrocitinib Long-Term Efficacy for up to 96 Weeks in Patients With Moderate-to-Severe Atopic Dermatitis: Interim Analysis of JADE EXTEND, a Long-Term Extension Study
Authors: Kristian Reich, Jonathan I. Silverberg, Marjolein de Bruin-Weller, Mette Deleuran, Lisa A. Beck, Kim Papp, Saleem A. Farooqui, Fan Zhang, Claire Feeney, Herwig Koppensteiner
Journal: Journal of the American Academy of Dermatology (2023)
43996 A cross-sectional study to find association of VDR gene polymorphism with non-syndromic congenital ichthyosis and with vitamin D deficiency
Authors: Rahul Mahajan, Hitaishi Kaushik, Garima Dabas, Niharika Shrivastava, Raihan Ashraf, Dipankar De, Arnab Pal, Rakesh Kumar, Sanjeev Handa
Journal: Journal of the American Academy of Dermatology (2023)
42924 Treatment-Emergent Adverse Events in Patients Aged 6 Months to 5 Years With Moderate-to- Severe Atopic Dermatitis Treated With Dupilumab in an Open-Label Extension Clinical Trial
Authors: Amy Paller, Elaine Siegfried, Robert Sidbury, Michael Cork, Andreas Pinter, Jing Xiao, Sarah Stanton, Faisal Khokhar, Ashish Bansal, Randy Prescilla
Journal: Journal of the American Academy of Dermatology (2023)
41489 A Double-Blind, Split-Face, Randomized Study on the Effects and Safety of Intradermal Injection of Botulinum Toxin A in the Cheek
Authors: Dong Min Shin, Jongeun Lee, Hyungrye Noh, Donghwi Jang, Heeyeon Kim, Se Jin Oh, Ji Hye Park, Jong Hee Lee
Journal: Journal of the American Academy of Dermatology (2023)
40212 The Global Prevalence of Primary Psychodermatologic Disorders: A Systematic Reviews
Authors: Chaocheng Liu, Tarek Turk, Sebastian Straube, Marlene Dytoc, Reidar Hagtvedt, Liz Dennett, Adam Abba-Aji, Esther Fujiwara
Journal: Journal of the American Academy of Dermatology (2023)
42807 A comparative study of the efficacy of oral omega-3 polyunsaturated fatty acids vectorized in marine phospholipids to prevent the post-inflammatory hyperpigmentation in dark skin types after a non-ablative laser
Authors: Valeria Campos, Celia Kalil, Luciane Zagonel, Caroline Rocha, Clarissa Reinehr, Patricia França
Journal: Journal of the American Academy of Dermatology (2023)
43966 Targeting interleukin-13 with tralokinumab reduces S. aureus abundance in adolescents with atopic dermatitis
Authors: Lisa A. Beck, Stephan Weidinger, Campus Kiel, Hidehisa Saeki, Alan D. Irvine, Lawrence Eichenfield, Thomas Werfel, Petra Arlert, Azra Kurbasic, Mads A. Røpke, Amy Paller
Journal: Journal of the American Academy of Dermatology (2023)
42007 The eﬃcacy and safety of botulinum toxin-loaded detachable dissolvable microneedles for primary axilla hyperhidrosis: A pilot study
Authors: Jidapa Triwatcharikorn, Titiporn Sansureerungsikul, Pravit Asawanonda, Supason Wanichwecharungruang, Nunthanach Chuenboonngarm, Kornphaka Kantikosum, Natcha Chottawornsak, Thanaporn Puaratanaarunkon, Chanat Kumtornrut, Puttikorn Pukfukdee, Ratchathorn Panchaprateep
Journal: Journal of the American Academy of Dermatology (2023)
43959 Vitiligo Noticeability Scale Score Maintenance or Shift During 52 Weeks of Ruxolitinib Cream Treatment for Vitiligo: Pooled Analysis of the TRuE-V Phase 3 Studies
Authors: Khaled Ezzedine, Thierry Passeron, David Rosmarin, Amit G. Pandya, Julien Seneschal, Deanna Kornacki, Haobo Ren, Kathleen Butler, Kristen Bibeau, Seemal R. Desai
Journal: Journal of the American Academy of Dermatology (2023)
42736 Safety Assessments in the Multinational Phase 3 THRIVE-AA1 Trial with CTP-543 (Deuruxolitinib) in Adult Patients with Moderate to Severe Alopecia Areata
Authors: Brett King, Natasha Atanaskova Mesinkovska, Maryanne Makredes Senna, Arash Mostaghimi, Colleen Hamilton, James Cassella
Journal: Journal of the American Academy of Dermatology (2023)
42412 Symptoms of gastrointestinal dysfunction in inflammatory dermatosis
Authors: David Castillo-Molina, Sara Muñoz-Ordoñez, Jesus Daniel Fierro-Lozada, Sofia Bernal-Alfonso, Samanda J. Suarez-Garcia, Tatiana Solórzano-Rojas, María Paula Muñoz-McCausland, David E. Castillo-Saavedra
Journal: Journal of the American Academy of Dermatology (2023)
40532 The Risk of Skin Cancer Among Patients with Atopic Dermatitis: A Population-Based Cohort Study
Authors: Margaret Y. Huang, Kathleen L. Miao, Kathryn Lee, Paige Kingston, Danielle Yee, Edwin Korouri, Hannah Peterson, Rosario Agüero, Khristina Lung, April Armstrong
Journal: Journal of the American Academy of Dermatology (2023)
43019 Spesolimab for hidradenitis suppurativa: A proof-of-concept study
Authors: Afsaneh Alavi, Errol Prens, Alexa B. Kimball, James G. Krueger, Sutirtha Mukhopadhyay, Hui Wang, Nathalie B. Ivanoff, Ana C. Hernandez Daly, Christos C. Zouboulis
Journal: Journal of the American Academy of Dermatology (2023)
43077 Tumor Characteristics and Clinical Outcomes for Cutaneous Squamous Cell Carcinoma in Immunosuppressed Patients
Authors: Adina Greene, Blake Boudreaux, Puneet Bhullar, Jacob Kechter, Angelina Hwang, Kevin Severson, Richard Butterfield, Nan Zhang, Steven Nelson, Shari Ochoa, Aaron Mangold
Journal: Journal of the American Academy of Dermatology (2023)
41574 Tapinarof Cream 1% Once Daily (QD) for Plaque Psoriasis: Psoriasis Area and Severity Index Score by Body Region for the PSOARING 1 and 2 Trials
Authors: Linda Stein Gold, Alexandra Golant, Rocco Serrao, Anna M. Tallman, Philip M. Brown
Journal: Journal of the American Academy of Dermatology (2023)
43699 Two cases of Nicolau syndrome: an avoidable entity
Authors: Anabell Andrea Lima-Galindo, Adalberto Santana-Guitiérrez, Alejandra de la O-Escamilla, Alejandra Villarreal-Martinez, Sonia Chávez-Álvarez, Jorge Ocampo-Candiani, Jorge Ocampo-Candiani
Journal: Journal of the American Academy of Dermatology (2023)
42999 Rocatinlimab demonstrates a significant reduction in IgE concentrations in addition to clinical eﬃcacy measures in patients with moderate–severe atopic dermatitis (msAD) in a randomised, double-blind, placebo-controlled Phase 2 trial
Authors: Emma Guttman-Yassky, Camilla Chong, Ehsanollah Esfandiari
Journal: Journal of the American Academy of Dermatology (2023)
42928 The patient-reported impact of itch and sleep interference on pediatric and adolescent patients with moderate and severe atopic dermatitis: a real-world study in the United States and Europe
Authors: Lawrence Eichenfield, Vivian Shi, JiaDe Yu, Evangeline Pierce, Amber Reck Atwater, Jenny Austin, Phoebe Salmon, James Piercy, Peter Anderson, Amy Paller
Journal: Journal of the American Academy of Dermatology (2023)
43060 A dermatologist, internist, and family medicine physician walk into an eczema patient visit: Comparing systemic corticosteroid prescribing patterns between dermatologists and primary care providers for AD
Authors: Meredith Xepoleas, Kathleen Miao, Hannah Peterson, Edwin Korouri, Paige Kingston, Margaret Y. Huang, Kathryn Lee, Danielle Yee, Madison E. Jones, April Armstrong
Journal: Journal of the American Academy of Dermatology (2023)
43437 Ustekinumab for the Treatment of Metastatic Crohn Disease
Authors: Grace McKay, Alexandra Coromilas, Lynn Liu, Michael Murphy, Nina Punyamurthy, William Damsky, Karolyn Wanat, Misha Rosenbach, Avrom Caplan, Charlotte LaSenna, Bridget Shields
Journal: Journal of the American Academy of Dermatology (2023)
41943 Skin of Color Representation in Laser and Light Treatments of Cosmetic Dermatologic Conditions: A Systematic Review
Authors: Priya Manjaly, Eric Xia, Alexandra Allan, Shreya Vinjamuri, Henriette De La Garza, Mindy Szeto, Cyriac Manjaly, Shaundra Eichstadt, Mayra Maymone, Neelam Vashi
Journal: Journal of the American Academy of Dermatology (2023)
42981 Secukinumab and concomitant antibiotic use in patients with moderate-to-severe hidradenitis suppurativa: Week 16 eﬃcacy and safety results from the Phase 3 SUNSHINE and SUNRISE trials
Authors: Georgios Kokolakis, Antonio Martorell, Francisco Kerdel, Vincenzo Bettoli, Evangelos J. Giamarellos-Bourboulis, Rodney Sinclair, Torben Kasparek, Xianjun Li, Angela Llobet Martinez, Lorenz Uhlmann, Elisa Muscianisi
Journal: Journal of the American Academy of Dermatology (2023)
41464 A randomized, controlled study to assess effectiveness and safety of correction of cheek wrinkles using a biostimulatory poly-L-lactic acid injectable implant
Authors: Deirdre Hooper, Sabrina Fabi, Tiffani Hamilton, Brenda LaTowsky, Rebecca Kazin, Keith Marcus, Flor Mayoral, John Joseph, Sachin Shridharani
Journal: Journal of the American Academy of Dermatology (2023)
43067 Risankizumab for the treatment of moderate-to-severe psoriasis: Real-world data from the Czech Republic BIOREP Registry
Authors: Martina Kojanova, Jorga Fialova, Petra Cetkovska, Spyridon Gkalpakiotis, Alena Machovcova, Petr Arenberger, Jiri Stork, Tomas Dolezal, Daniela Strosova
Journal: Journal of the American Academy of Dermatology (2023)
43531 Validation of the Dermatology Life Quality Index (DLQI) in prurigo nodularis (PN) based on clinical studies of dupilumab in adults with PN
Authors: Donia Bahloul, Ryan B. Thomas, Stephanie Rhoten, Nadine Häusler, Sonja Ständer, Brian S. Kim, John T. O’Malley, Ashish Bansal, Jerome Msihid
Journal: Journal of the American Academy of Dermatology (2023)
42917 Safety and eﬃcacy of lebrikizumab in adolescent patients with moderate-to-severe atopic dermatitis: an open-label study
Authors: Amy Paller, Carsten Flohr, Lawrence F. Eichenfield, Alan Irvine, Ana Pinto Correia, Chitra R. Natalie, Evangeline Pierce, Sarah Reifeis, Renata Gontijo Lima, Vivian Laquer, Stephan Weidinger
Journal: Journal of the American Academy of Dermatology (2023)
42262 Sustained Improvement Over 52 Weeks in Patient-Reported Itch, Symptoms, and Quality of Life With Upadacitinib in Patients With Atopic Dermatitis: Results From Phase 3 Studies (Measure Up 1, Measure Up 2, and AD Up)
Authors: Jonathan I. Silverberg, Mette Deleuran, Linda S. Gold, Christopher G. Bunick, Dirk Jan Hijnen, Brian M. Calimlim, Henrique D. Teixeira, Andrew M. Platt, Ayman Grada, Xiaofei Hu, Melinda Gooderham
Journal: Journal of the American Academy of Dermatology (2023)
44103 Ruxolitinib Cream Monotherapy Use Demonstrates Maintenance of Disease and Symptom Control With Use As Needed in Adults and Adolescents With Atopic Dermatitis: Pooled Analysis From the Long Term Safety Periods of Two Phase 3 Studies
Authors: Andrew Blauvelt, Leon Kircik, Eric Simpson, Peter Lio, Daniel Sturm, Howard Kallender, Haobo Ren, Dilan Paranagama, Jessy Gao, Lawrence Eichenfield
Journal: Journal of the American Academy of Dermatology (2023)
41279 Real-World Switch Rates of Biologics and Associated Costs in Patients With Psoriasis
Authors: Jashin J. Wu, Manish Patel, Chao Li, Vishvas Garg, Monika Rao Mandava, April W. Armstrong
Journal: Journal of the American Academy of Dermatology (2023)

Background: Patients may switch therapies if they experience poor treatment outcomes such as efficacy or safety/tolerability issues. This real-world study quantifies switching rates, healthcare resource use, and treatment costs among patients with psoriasis.
42939 Remibrutinib Treatment Improves Itch and Sleep in Chronic Spontaneous Urticaria Patients: Phase 2b Study Results
Authors: Connie Hsu, Robert Snyder, Lee Clore, Vipul Jain, Ana Giménez-Arnau, Karine Lheritier, Pauline Walsh, Sibylle Haemmerle, Michael Wells, Ivan Nikolaev, Marcus Maurer
Journal: Journal of the American Academy of Dermatology (2023)