tbuckley/cabot-search huggingface dataset:
CAR-T Cell Therapy in First Line for High Risk Diffuse Large B-Cell Lymphoma: Review of Efficacy and Cost-Effectiveness Against Standard of Care Chemo-Immunotherapy
Authors: Usman Ali Akbar, Zaraq Rashid, Zarlish Rehman, Shehzad Alam, Zooha Altaf, Rana Usman Anwar, Adil Khan, Jafir Wakeel, Saad Farooq, Muhammad Haris Khan, Danish Safi, Arslan Inayat, Salah Ud Din Safi
Journal: Blood (2022)
Γ-Secretase Inhibitors Enhance the Potency of BCMA-Targeting T Cell Engagers Against Multiple Myeloma Cells without Adverse Impact on T-Cell Activation and Differentiation
Authors: Hailin Chen, Tengteng Yu, Liang Lin, Lijie Xing, Shih-Feng Cho, Kenneth Wen, Kimberly Aardalen, Mike Daley, Haihui Lu, Adwait Oka, Joni Lam, Nikhil C Munshi, Kenneth C. Anderson, Yu-Tzu Tai
Journal: Blood (2022)
XPO1 Overexpression Is a Mechanism of Resistance to Eprenetapopt and 5-Azacitidine Therapy That Can be Therapeutically Exploited for the Treatment of <i>TP53</i> Mutated Myeloid Malignancies
Authors: Traci L. Kruer, Ariel Quintana, Meghan Ferrall-Fairbanks, Ling Zhang, Hannah Newman, Amy F McLemore, Qin Yang, Nana Bencrentsil, Rami S. Komrokji, Sana Chaudhry, Tulasigeri M Totiger, Maria Ken E. Figueroa, Justin Taylor, David A. Sallman, Eric Padron
Journal: Blood (2022)
Engineered Stem Cell Antibody Paired Evasion 1 (ESCAPE-1): Paired HSC Epitope Engineering and Upregulation of Fetal Hemoglobin for Antibody-Mediated Autologous Hematopoietic Stem Cell Therapy Conditioning for the Treatment of Hemoglobinopathies
Authors: Nandini Mondal, Alexander Harmon, Elizabeth Budak, Kathy Zhang, Jeffrey Wong, Conrad Rinaldi, Jenny Olins, Kara Hoar, Archita Venugopal Menon, Moriah White, Faith Musenge, Adam Camblin, Adam Wolin, Brent Coisman, Tao Bai, Kangjian Qiao, Mudra Patel, Jeremy Decker, Bob Gantzer, Thomas Leete, Yi Yu, Tanggis Bohnuud, Seung-Joo Lee, Sarah Smith, Charlotte F McDonagh, Nicole M. Gaudelli, S. Haihua Chu, Adam J. Hartigan, Giuseppe Ciaramella
Journal: Blood (2022)
Sars-Cov-2 Fails to Infect Mesenchymal Stromal Cells (MSCs) - Pre-Clinical Investigations in Support of Therapeutic Use of MSCs for Severe COVID-19
Authors: Lisa-Marie Pfeffermann, Denisa Bojkova, Joshua Kandler, Sabine Huenecke, Melanie Bremm, Natascha Piede, Selim Kuci, Zyrafete Kuci, Sabine Harenkamp, Halvard Bonig, Peter Bader
Journal: Blood (2022)
Engineering Novel Multi-Cytokine Backpacks for Manufacturing Functionally Improved CAR T Cell Products
Authors: Heather Lin, A K M Nawshad Hossian, Biaggio Uricoli, Ruby Mei Freeman, Dejah A Blake, Jonathan Legier, Remya Nair, Jean L. Koff, Mala Shanmugam, Erik Dreaden, Sarwish Rafiq
Journal: Blood (2022)
Efficacy and Safety of Ibrutinib Combined with Standard First-Line Treatment or As Substitute for Autologous Stem Cell Transplantation in Younger Patients with Mantle Cell Lymphoma: Results from the Randomized Triangle Trial By the European MCL Network
Authors: Martin Dreyling, Jeanette K. Doorduijn, Eva Gine, Mats Jerkeman, Jan Walewski, Martin Hutchings, Ulrich Mey, Jon Riise, Marek Trneny, Vibeke K.J. Vergote, Melania Celli, Ofer Shpilberg, Maria Gomes da Silva, Sirpa Leppa, Linmiao Jiang, Christiane Pott, Wolfram Klapper, Döndü Gözel, Christian Schmidt, Michael Unterhalt, Marco Ladetto, Eva Hoster
Journal: Blood (2022)
Novel Observation That Trafficking of Hematopoietic Stem Progenitor Cells (HSPCs) Involves Activation of Nlrp3 Inflammasome That Provides Cholesterol and Sphingolipids for the Formation of Lipid Rafts on the Outer Cell Membrane That Are Crucial for Proper Responsiveness of HSPCs to Chemoattractant and Hematopoietic Cytokines/Growth Factors
Authors: Andrzej Ciechanowicz, Ahmed Abdelbaset-Ismail, Magda Kucia, Mariusz Z Ratajczak
Journal: Blood (2022)
Efficient Multiplex Gene Editing of CD33 and CLL-1 in Human Hematopoietic Stem Cells Enables the Potential of Next-Generation Transplants for AML Treatment
Authors: Juliana Xavier-Ferrucio, Gabriella Angelini, Sushma Krishnamurthy, Nipul Patel, Michael Pettiglio, Timothy Collingsworth, Amanda Halfond, Julia Etchin, Yonina Keschner, Guy Mundelboim, Huan Qiu, Ruijia Wang, Gary Ge, John Lydeard, Michelle I Lin, Tirtha Chakraborty
Journal: Blood (2022)
Phase 2 Study of Daratumumab (DARA) Plus Bortezomib, Cyclophosphamide, and Dexamethasone (D-VCd) in Patients with Newly Diagnosed Amyloid Light Chain (AL) Amyloidosis: Aquarius
Authors: Vaishali Sanchorawala, Michael Rosenzweig, Christopher Pericone, Sandra Y. Vasey, Xiang Qin, Sonja Marie Kotoulek, Bart Vandael, Joana Duran, Samer Khaled, NamPhuong Tran, Efstathios Kastritis
Journal: Blood (2022)
Mgta-117, an Anti-CD117 Antibody-Drug Conjugated with Amanitin, in Participants with Relapsed/Refractory Adult Acute Myeloid Leukemia (AML) and Myelodysplasia with Excess Blasts (MDS-EB): Safety, Pharmacokinetics and Pharmacodynamics Initial Findings from a Phase 1/2 Study
Authors: Peter Westervelt, Partow Kebriaei, Mark Juckett, Andrew S. Artz, Onyee Chan, Philip L. McCarthy, Sherif S Farag, Anurag K. Singh, Eytan Stein, Jeffrey Humphrey, William Baeder, Ji Hyun Lee, Alison Occhiuti, Jeanie Tang, David Santos, Kirk Bertelsen, Balaji Mahender, Nicole Henry, Shawn Rose
Journal: Blood (2022)
Study of Venetoclax Plasma Concentrations during Co-Administration with Posaconazole in Acute Myeloid Leukemia (AML) Patients
Authors: Patrizia Zappasodi, Simona De Gregori, Eleonora Gelli, Elisa Roncoroni, Marianna Rossi, Claudia Patricia Tobar Cabrera, Eugenio Santacroce, Gianluca Martini, Ludovica Calabretta, Riccardo Albertini, Luca Arcaini
Journal: Blood (2022)
Abnormal Cytotoxic T-Cell Expansion in the Bone Marrow of Patients with SASH3 Deficiency and Cytopenias
Authors: Saber Tadros, Shamik Majumdar, Ottavia Delmonte, Jenna Bergerson, Irene Cortese, David H. McDermott, Jaspal Khillan, Kyoungin Cho, Luigi D. Notarangelo, Philip M. Murphy, Katherine R. Calvo
Journal: Blood (2022)
Molecular and Clinical Features of <i>FLT3</i> Juxtamembrane Domain Point Mutations (muts) in Acute Myeloid Leukemia (AML)
Authors: Nadeen Anabtawi, Jessica Kohlschmidt, Daelynn Buelow, Shelley Orwick, Kennedy Coleman, Krzysztof Mrózek, Jonathan E. Kolitz, Bayard L. Powell, William G. Blum, Maria R. Baer, John C. Byrd, Wendy Stock, Geoffrey L. Uy, Ann-Kathrin Eisfeld, Sharyn Baker, James S. Blachly
Journal: Blood (2022)
Efficiency and Safety of Zanubrutinib Combined with R-CHOP Regimen in the Treatment of Newly Diagnosed Patients with Double Expressor Diffuse Large B-Cell Lymphoma: A Single-Center Retrospective Study
Authors: Meichen Liu, Qianxue Guo, Bin Liu, Xinning Xu, Mengdan Xu, Lili Liu, Xinxin Li, Xiaojing Xing
Journal: Blood (2022)
A Phase IV, Multicenter, Open-Label, Safety, and Efficacy Study of High-Dose, Propylene Glycol-Free Melphalan Hydrochloride for Injection (EVOMELA) As a Myeloablative Conditioning Regimen in Chinese Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation
Authors: Fengrong Wang, Zhen Cai, Dehui Zou, Wenming Chen, Yongping Song, Chengcheng Fu, Jiong Hu, Ting Yang, Xinchuan Chen, Jinsong Yan, Kaiyan Liu
Journal: Blood (2022)
Overexpression of CXCR4 Enhances the Efficacy of CAR-T Therapy for Acute Myeloid Leukemia
Authors: Marta Biondi, Stefania Galimberti, Beatrice Cerina, Chiara Tomasoni, Gianpietro Dotti, Sarah Tettamanti, Andrea Biondi, Alice Pievani, Marta Serafini
Journal: Blood (2022)
Multiple Myeloma-Derived Mir-27b-3p Facilitates Tumor Progression Via Promoting Tumor Cell Proliferation and Immunosuppressive Microenvironment
Authors: Xiaojing Wei, Zhen Yu, Hao Sun, Lixin Gong, Lanting Liu, Teng Fang, Yi He, Tingyu Wang, Weiwei Sui, Yan Xu, Gang An, Xiaoke Ma, Lugui Qiu, Mu Hao
Journal: Blood (2022)
Cumulative Organ Dysfunction and Functional Status before and after Intensive Care Unit Admission Are Strong Predictors of Mortality in Patients with Hematologic Malignancies
Authors: Ana Vagos Mata, Daniel Gomes, Pedro Mendonça, Pedro De Vasconcelos, Daniela Alves, João Santos Silva, João Ribeiro, João F Lacerda, João Raposo
Journal: Blood (2022)
Comparison of Fludarabine/Melphalan (FluMel) with Fludarabine/Melphalan/BCNU or Thiotepa (FBM/FTM) in Patients with AML in First Complete Remission Undergoing Allogeneic Hematopoietic Stem Cell Transplantation - a Registry Study on Behalf of the EBMT Acute Leukemia Working Party
Authors: Jesus Duque Afonso, Jürgen Finke, Maud Ngoya, Jacques-Emmanuel Galimard, Charles Craddock, Kavita Raj, Adrian Bloor, Emma Nicholson, Matthias Eder, Kim H. Orchard, Thomas Valerius, John A. Snowden, Eleni Tholouli, Charles Crawley, Matthew P. Collin, Keith Wilson, Alain Gadisseur, Rachel Elizabeth Protheroe, Eva Maria Wagner, Bipin Savani, Alexandros Spyridonidis, Fabio Ciceri, Arnon Nagler, Mohamad Mohty
Journal: Blood (2022)
Plasma Cell Leukemia: A Multicenter Retrospective Study of 130 Patients
Authors: Iloabueke Chineke, Betsy Wertheim, Denise Roe, Ashley Larsen, Victoria A. Vardell, Douglas W. Sborov, Damian J. Green, Michaela Liedtke, Marie Okoniewski, Mohammed Wazir, Omar Nadeem, Levanto Schachter, David Coffey, Krisstina L. Gowin, Dominique DeGraaff
Journal: Blood (2022)
Genomic and Transcriptional Profiling Stratifies Vq Myeloma Lines into Two Clusters with Distinct Risk Signatures and Drug Responses
Authors: Evan Flietner, Mei Yu, Adhithi Rajagopalan, Yun Zhou, Yubin Feng, Anthony Veltri, Terra Lasho, Zhi Wen, Yuqian Sun, Robert Burns, Mrinal M. Patnaik, Natalie Callander, Fotis Asimakopoulos, Demin Wang, Jing Zhang
Journal: Blood (2022)
EBV Dictates Lower Tumor Neoepitopes Scores and Intra-Tumoral Repertoire Diversity in NHL from Immuno-Compromized Patients
Authors: Marine Baron, Karim Labreche, Amira Bouzidi, Marianne Veyri, Nathalie Désiré, Véronique Leblond, Florence Coulet, Pierre-Yves Boelle, Fatou Seck Thiam, Damien Roos-Weil, Frédéric Charlotte, Frederic Davi, Elsa Poullot, Alice Rousseau, Corinne Haioun, Jean-Philippe Spano, Brigitte Autran, Choquet Sylvain, Amélie Guihot
Journal: Blood (2022)
Prophylactic Corticosteroid Use with Axicabtagene Ciloleucel (Axi-Cel) in Patients (Pts) with Relapsed/Refractory Large B-Cell Lymphoma (R/R LBCL): 2-Year Follow-up of ZUMA-1 Cohort 6
Authors: Olalekan O. Oluwole, Edouard Forcade, Javier Muñoz, Sophie de Guibert, Julie M. Vose, Nancy L. Bartlett, Yi Lin, Abhinav Deol, Peter A. McSweeney, Andre H. Goy, Marie José Kersten, Caron A. Jacobson, Umar Farooq, Monique C. Minnema, Catherine Thieblemont, John Timmerman, Patrick Stiff, Irit Avivi, Dimitrios Tzachanis, Yan Zheng, Saran Vardhanabhuti, Jenny Nater, Rhine R. Shen, Harry Miao, Jenny Kim, Tom van Meerten
Journal: Blood (2022)
First-Line Treatment and Outcome of T-Cell Prolymphocytic Leukemia in the Netherlands; A Nationwide Population-Based Study
Authors: Mirian Brink, Arie C. van der Spek, Koen de Heer, Sabina Kersting, Lidwine W. Tick, Hanneke M. van der Straaten, Rogier Mous, Mark-David Levin, Doreen te Raa, Michel van Gelder, Jeanette K. Doorduijn, Arnon P. Kater, Gerwin Huls, Mar Bellido
Journal: Blood (2022)
Clinical Outcomes in <i>De Novo</i> Versus Secondary <i>NPM1</i>-Mutated AML
Authors: Elliot C. Smith, Eshetu G. Atenafu, Aniket Bankar, Steven M. Chan, Marta B. Davidson, Vikas Gupta, Mark D. Minden, Guillaume Richard-Carpentier, Aaron D. Schimmer, Andre C. Schuh, Hassan Sibai, Karen Yee, Dawn Maze
Journal: Blood (2022)
Myosteatosis As a Predictor of Toxicity Among Older Adults with DLBCL Receiving CHOP-Based Regimens
Authors: Star Ye, Christian Harmon, Nadia Anabtawi, Clare Ubersax, Abigail Tucker, Gaurav Goyal, Lauren Shea, Mayur Narkhede, Amitkumar Mehta, Purnima Singh, Grant Williams, Smita Bhatia, Smith Giri
Journal: Blood (2022)
Initial Efficacy and Safety of Acalabrutinib Plus RICE in Transplant Eligible Patients with Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Authors: Neil Bailey, Tori Braun, Megumi Bailey, Tenzin Tsomo, Jennie Szeto, Sandra Benitez Kruidenier, Vanessa Dunleavy, Joanna Fesler, Gayle Funk, Sonia Glennie, Judson Hall, Julia Parker, Daniel Egan, Raya Mawad, Carol A Dean, Suzan Sullivan, Chia Lu, Heidi Hohmann, Jordan Briggs, Krish Patel
Journal: Blood (2022)
Olverembatinib (HQP1351) Overcomes Ponatinib Resistance in Patients with Heavily Pretreated/Refractory Chronic Myeloid Leukemia (CML) and Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL)
Authors: Elias Jabbour, Paul B. Koller, Vivian G. Oehler, Omer H Jamy, Sudipto Mukherjee, Anthony M. Hunter, Maria R. Baer, Joseph T. Beck, Zi Chen, Huanshan Guo, Lei Fu, Lichuang Men, Hengbang Wang, Dajun Yang, Yifan Zhai, Hagop Kantarjian, Lixin Jiang, Cunlin Wang
Journal: Blood (2022)
Dose Optimization to Mitigate the Risk of CRS with Elranatamab in Multiple Myeloma
Authors: Mohamed Elmeliegy, Andrea Viqueira, Erik Vandendries, Anne Hickman, Jennifer Hibma, Hoi-Kei Lon, Joseph Piscitelli, Pooneh Soltantabar, Diane Wang, Sibo Jiang, Gregory Finn, Akos Czibere
Journal: Blood (2022)
Daratumumab,Pomalidomide and Dexamethasone (DPd) Versus Daratumumab, Velcade and Dexamethasone (DVd) in Previously Treated Daratumumab Naïve Relapsed Refractory Multiple Myeloma Patients
Authors: Evguenia Ouchveridze, Chandandeep Singh, Shebli Atrash, Barry Paul, Meera Mohan, Omar Alkharabsheh, Aimaz Afrough, Wei Cui, Zahra Mahmoudjafari, Al-Ola Abdallah, Hamza Hashmi
Journal: Blood (2022)
Immune Response to Covid-19 Vaccination in Patients with Chronic Lymphocytic Leukaemia (CLL): An Experience from Two Italian Centres
Authors: Idanna Innocenti, Roberta Murru, Giulia Benintende, Andrea Galitzia, Antonio Mosca, Luca Barabino, Luca Stirparo, Annamaria Tomasso, Alberto Fresa, Francesco Autore, Giovanni Caocci, Giorgio La Nasa, Luca Laurenti
Journal: Blood (2022)
Hemolytic Markers, Mortality, and Thromboembolic Events in Cold Agglutinin Disease (CAD): A Retrospective Analysis of the Optum Electronic Health Record Database in the United States
Authors: Catherine M. Broome, Wilma Barcellini, Alexander Roeth, Alia Karaouni, Florence Joly, Ronnie Yoo, Augustin Terlinden, Ayo Adeyemi, Yola Moride, Quentin A. Hill
Journal: Blood (2022)
<i>Patient Characteristics, Treatment Patterns, and Cost Variations By Race/Ethnicity Among Adults with Relapsed or Refractory Acute Lymphoblastic Leukemia Initiating First Salvage Therapy</i>
Authors: Megan C Braunlin, Tingting Gong, Rebecca Payne, Chuanyu Kou, Babatunde Adedokun, Kelly Velasco, Shuling Li
Journal: Blood (2022)
Benchmarking of Whole Genome Sequencing (WGS) and Whole Transcriptome Sequencing (WTS) As Diagnostic Tools for Determining the Mutation Status of IGHV Genes in CLL
Authors: Heiko Mueller, Wencke Walter, Stephan Hutter, Niroshan Nadarajah, Frank Dicker, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach
Journal: Blood (2022)
A Phase 1/2, First-in-Human, Multicenter, Open-Label, Dose Escalation and Dose-Expansion Study of Single-Agent ISB 1442 in Patients with Relapsed/Refractory Multiple Myeloma
Authors: Hanlon Sia, Peter T. Tan, Joshua Richter, Phoebe Joy Ho, Tara Cochrane, Hang Quach, Binod Dhakal, Igor Proscurshim, Tony Jiang, Emaryn Mancino, Yacine Salhi, Sammicheli Stefano, Girish Gudi, Andrew Garton, Eric J. Feldman, Andrew Spencer
Journal: Blood (2022)
A Phase I Study of FT538, an Off-the-Shelf, Multiplexed-Engineered, iPSC-Derived NK Cell Therapy in Combination with Daratumumab in Relapsed/Refractory Multiple Myeloma
Authors: Mark Juckett, Sham Mailankody, Alireza Eghtedar, Cara Bickers, Xingyue Zong, Lilly Wong, Thomas Ly, John Byon, Sarah Cooley, Bahram Valamehr, Yu-Waye Chu, Ravi Vij
Journal: Blood (2022)
The Anti-HIV Drug Nelfinavir Exhibits Synergistic Activity with Tyrosine Kinase Inhibitors and Circumvents TKI-Resistance Conferred By T315I-Mutated BCR-ABL
Authors: Yücel Erbilgin, Christophe Desterke, Annelise Bennaceur Griscelli, Ali G Turhan
Journal: Blood (2022)
Prevention of Docetaxel (Doc)-Induced Neutropenia (DIN) with Single Agent Plinabulin (Plin) Versus (vs) Control (No-Treatment or Placebo) in Non-Small Cell Lung Cancer (NSCLC) in Two Randomized Trials
Authors: Douglas W. Blayney, Stephan Ogenstad, Gabrielle Legaspi, Stephen Duprez, Lan Huang, Ramon W. Mohanlal
Journal: Blood (2022)
Vitalize Trial: A Phase 2b, Open-Label, Multicenter, Randomized Parallel-Group, Two-Stage, Study of the Novel Immunotherapeutic, Maveropepimut-S, and Pembrolizumab with and without Intermittent Low-Dose Cyclophosphamide, in Subjects with Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Authors: Matthew J. Matasar, Eric Lee, Sophie Leitch, Melhem Solh, Jennifer Teti, Kabir Mody, Stephan Fiset, Jeremy Graff
Journal: Blood (2022)
Inotuzumab Ozogamicin (InO) Combined with UKALL-R3 Modified Chemotherapy in Pediatric Patients with B-Cell Precursor CD22+ Acute Lymphoblastic Leukemia (BCP-ALL) - Results from the ITCC-059 Phase 1B Trial
Authors: Edoardo Pennesi, Erica Brivio, Anneke C.J. Ammerlaan, Yilin Jiang, Vincent H.J. van der Velden, Berna Beverloo, Barbara Sleight, Susana Rives, Cristina Díaz de Heredia Rubio, Francisco J. Bautista Sirvent, Alba Rubio-San-Simón, Fanny Rialland, Carmelo Rizzari, Bella Bielorai, Arnaud Petit, Bénédicte Bruno, Ingrid Øra, Anna Nilsson, Gernot Engstler, Claudia Rossig, Benoit Brethon, Franco Locatelli, Christian M. Zwaan
Journal: Blood (2022)
Circulating miRNA Profiling of Plasma Samples from Patients with Newly Diagnosed Multiple Myeloma; A Biomarker Study to Predict the Response and Toxicity of Bortezomib-Containing Regimen: An Ancillary Study of JCOG1105 (JCOG1105A1)
Authors: Masaki Ri, Shimon Nakashima, Miki Nakajima, Shinsuke Iida, Dai Maruyama, Satoshi Osaga, Kensei Tobinai, Noriko Fukuhara, Kana Miyazaki, Norifumi Tsukamoto, Hideki Tsujimura, Makoto Yoshimitsu, Kenichi Miyamoto, Kunihiro Tsukasaki, Hirokazu Nagai
Journal: Blood (2022)
MIP3α As an Early Prognostic Predictor for Patients with B-Cell Malignancies Receiving CD19/CD22-Redirected CAR T-Cell Cocktail Therapy
Authors: Jin Jin, Jiali Cheng, Na Wang, Liang Huang, Xiaoxi Zhou, Liting Chen, Hui Luo, Tianjiao Liu, Jiao Meng
Journal: Blood (2022)
A Method to Estimate Whole Blood Concentration of Voxelotor in People with Sickle Cell Disease Using High Performance Liquid Chromatography and Capillary Electrophoresis
Authors: Susanna Curtis, Elana M Friedman, Caterina P Minniti, Annie Ngyuen Dang, Mira P. Pochron, Julissa Morales, Andrew Crouch, Sean Campbell
Journal: Blood (2022)
Resistance to CD19 Immunotherapy in B-Cell ALL Is Associated with Loss of CD19 and CD22 and an Enhanced Vulnerability to B Cell Receptor Signaling Inhibition
Authors: Sarah Aminov, Orsi Giricz, R. Alejandro Sica, Veronika Polishchuk, Bonnie Yates, Hao-Wei Wang, Yanhua Wang, Srabani Sahu, Shanisha Gordon, Carolina Schinke, Kith Pradhan, Srinivas Aluri, Murali Janakiram, Stefan K. Barta, Beamon Agarwal, Mendel Goldfinger, Aditi Shastri, William Matsui, Ulrich Steidl, Joshua Brody, Nirali N. Shah, Samir Parekh, Amit Verma
Journal: Blood (2022)
Induction Quadruplet Therapy and Minimal/Measurable Residual Disease (MRD)-Informed Treatment Adaptation in Newly Diagnosed Multiple Myeloma (NDMM): Results from an Academic-Community Pathway
Authors: Gayathri Ravi, Smith Giri, Susan Bal, Kelly N. Godby, Vishnu V.B. Reddy, Donna Salzman, Omar Alkharabsheh, Scott A. McDaniel, Melissa Sentell, Luciano J. Costa
Journal: Blood (2022)
UBE2N Is a Druggable Target and an Essential Ubiquitin-Conjugating Enzyme in Myeloid Malignancies
Authors: Chiharu Ishikawa, Laura Barreyro, Avery Sampson, Kathleen Hueneman, Kwangmin Choi, Lyndsey C Bolanos, Andrew Volk, Kenneth D Greis, Daniel T. Starczynowski
Journal: Blood (2022)
Combination of Baseline Total Metabolic Tumor Volume Measured on FDG-PET/CT, ECOG Performance Status and β2-Microglobulin Have a Robust Predictive Value in Patients with Primary Breast Lymphoma
Authors: Peiqi Zhao, Lei Zhu, Lanfang Li, Shiyong Zhou, Lihua Qiu, Kai Fu, Huilai Zhang
Journal: Blood (2022)
Risk-Adapted Therapy Directed According to Response (RADAR, UK-MRA Myeloma XV) - Comparing MRD-Guided Treatment Escalation and De-Escalation Strategies in Patients with Newly Diagnosed Myeloma Suitable for Stem Cell Transplantation
Authors: Kwee Yong, Kara-Louise Royle, Karthik Ramasamy, Christopher Parrish, Anna Hockaday, Samir Asher, Mark T Drayson, Ruth M. de Tute, Matthew W Jenner, Martin F. Kaiser, Guy Pratt, Jonathan Sive, Ceri Bygrave, Gordon Cook, Rakesh Popat, Dean Smith, Catherine Olivier, Lorna Barnard, Doina Levinte, Bryony Dawkins, Michael A Chapman, Andrew D Chantry, Graham Jackson, Sergio A Quezada, Roger G Owen, David Cairns
Journal: Blood (2022)
<i>In silico</i> and Functional Studies for Classification of <i>EPAS1/HIF2A</i> Genetic Variants Identified in Patients with Erythrocytosis
Authors: Valéna Karaghiannis, Darko Maric, Céline Garrec, Nada Maaziz, Alexandre Buffet, Vincent Antunes, Amandine le Roy, Fabrice Airaud, Bernard Aral, Loic Schmitt, Sébastien Corbineau, Lamisse Mansour-Hendili, Valentine Lesieur, Antoine Rimbert, Fabien Laporte, Marine Delamare, Stephane Bezieau, Bruno Cassinat, Frédéric Galactéros, Anne-Paule Gimenez-Roqueplo, Nelly Burnichon, Holger Cario, Richard van Wijk, Celeste Bento, Anaise Blouet, Juliette Bouteloup, Françoise Boyer perrard, Aisha Aiko Bruce, Emilie Cayssials, Nicole Casadevall, Brieuc Cherel, Marielaure Couec, Louis Drevon, Cecile Dumesnil, Thierry Lamy De La Chapelle, Marion Gambart, Loic Garcon, Brigitte Granel, Pierre Hirsch, Agnès Lahary, Amira Mejri, Sandrine Meunier, Franck E. Nicolini, Emmanuel Raffoux, Dana Ranta, Nicolas Schleinitz, Jean Baptiste Valentin, Mathieu Wemeau, Francois Girodon, David Hoogewijs, Betty Gardie, Olivier Hermine
Journal: Blood (2022)
Safety, Tolerability, PK/PD and Preliminary Efficacy of NKTR-255, a Novel IL-15 Receptor Agonist, in Patients with Relapsed/Refractory Hematologic Malignancies
Authors: Krina Patel, Nina Shah, Alan Tan, Andrew J Cowan, Cameron J. Turtle, Craig C Hofmeister, Taewoong Choi, Hayder Saeed, Julio C. Chavez, Matthew J. Pianko, Mitul Gandhi, Sohail A. Chaudhry, Zachary Lee, Neha Dixit, Christie Fanton, Xiaoli Wang, Heng Xu, Mario Q. Marcondes, Mary A. Tagliaferri, Jonathan Zalevsky, Miguel-Angel Perales
Journal: Blood (2022)
Preliminary Results from an Observational Multicenter Study of Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm Treated with Tagraxofusp in the European Expanded Access Program
Authors: Eric Deconinck, Madhu Anant, David Manteigas, Carole Paley, Marcello Riggi, Marco Herling, Emanuele Angelucci
Journal: Blood (2022)
Shared Graft Versus Leukemia Minor Histocompatibility Antigens in DISCOVeRY-BMT
Authors: Kelly Shea Olsen, Othmane Jadi, Sarah Dexheimer, Dante Bortone, Steven Vensko, Hancong Tang, Marisa Diiorio, Tanvi Saran, David Dingfelder, Sarah Bennett, Qianqian Zhu, Yiwen Wang, Christopher A. Haiman, Loreall Pooler, Xin Sheng, Amy Webb, Marcelo C Pasquini, Philip L. McCarthy, Stephen R. Spellman, Eric T. Weimer, Theresa E. Hahn, Lara E. Sucheston-Campbell, Paul M. Armistead, Benjamin G. Vincent
Journal: Blood (2022)
Quantitative MRI Detects Multi-Organ Impairment in Patients with Chronic Myeloid Neoplasms
Authors: Oni Chowdhury, Sophie Reed, Alison Telford, Adriana Roca-Fernandez, Samiya Mahmood, Soubera Rymell, Michael Smith, Antonella Sultana, Nicole Eichert, Michele Pansini, Helena Thomaides-Brears, Bethan Psaila, Adam J Mead
Journal: Blood (2022)
A Five-Year Follow-up on Safety and Efficacy of Olverembatinib (HQP1351), a Novel Third-Generation BCR-ABL Tyrosine Kinase Inhibitor (TKI), in Patients with TKI-Resistant Chronic Myeloid Leukemia (CML) in China
Authors: Qian Jiang, Zongru Li, Ya-Zhen Qin, Ting Zhao, Bingcheng Liu, Zi Chen, Qian Niu, Lichuang Men, Hengbang Wang, Dajun Yang, Yifan Zhai, Xiao-Jun Huang
Journal: Blood (2022)
Rearrangements Involving 11q23/<i>KMT2A</i>: Mutational Landscape and Prognostic Implications - Results of the Harmony Alliance AML Database
Authors: Alberto Hernández Sánchez, Teresa González, Marta Anna Sobas, Eric Sträng, Castellani Gastone, María Abáigar, Peter JM Valk, Angela Villaverde Ramiro, Axel Benner, Klaus H. Metzeler, Jesse M. Tettero, Joaquín Martínez-López, Marta Pratcorona, Javier Martinez Elicegui, Ken I Mills, Christian Thiede, Guillermo Sanz, Konstanze Döhner, Michael Heuser, Torsten Haferlach, Amin T. Turki, Dirk Reinhardt, Renate Schulze-Rath, Martje Barbus, Jesús María Hernández-Rivas, Brian James Patrick Huntly, Gert Ossenkoppele, Hartmut Döhner, Lars Bullinger
Journal: Blood (2022)