tbuckley/cabot-search huggingface dataset:
Spemanns Historischer Medicinal-Kalendar, bearbeitet von Prof. Dr. J. Pagel und Prof. Dr. J. Schwalbe in Berlin.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MASSIVE INFECTION OF A VACCINATED PERSON WITH BACILLUS TYPHOSUS
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ANOTHER WELL-INTENDED LAW IS FOUND INVALID.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CORRECTION
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Molecular Basis of Neural-Specific Gene Expression
Authors: M. Gail Mandel and David
Journal: Annual Review of Neuroscience (1993)

The brain's default mode network consists of discrete, bilateral and symmetrical cortical areas, in the medial and lateral parietal, medial prefrontal, and medial and lateral temporal cortices of the human, nonhuman primate, cat, and rodent brains. Its ...Read More
A comparison of the safety and efficacy of alefacept 30 mg IM weekly for 12 weeks with alefacept 30 mg IM weekly for 6 weeks followed by alefacept 15 mg IM weekly for 6 weeks in patients with chronic plaque psoriasis
Authors: Metronidazole 75%, A Meta-, James Campbell
Journal: Journal of the American Academy of Dermatology (2005)
Progress Toward Poliomyelitis Eradication — Afghanistan, January 2015‒August 2016
Authors: Chukwuma Mbaeyi, Hemant Shukla, Philip Smith, Rudolf H. Tangermann, Maureen Martinez, Jaume C. Jorba, Stephen Hadler, Derek Ehrhardt
Journal: MMWR Morbidity and Mortality Weekly Report (2016)

Only 74 cases of wild poliovirus (WPV) were reported globally in 2015, the lowest number of cases ever reported worldwide (1,2). All of the reported cases were WPV type 1 (WPV1), the only known WPV type still circulating; WPV type 2 has been eradicated, and WPV type 3 has not been detected since November 2012 (1). In 2015 in Afghanistan, WPV detection also declined from 2014, and trends observed in 2016 suggest that circulation of the virus is limited to a few localized areas. Despite the progress, there are concerns about the ability of the country's Polio Eradication Initiative (PEI) to meet the goal of interrupting endemic WPV transmission by the end of 2016 (3). The deteriorating security situation in the Eastern and Northeastern regions of the country considerably limits the ability to reach and vaccinate children in these regions. Furthermore, because of frequent population movements to and from Pakistan, cross-border transmission of WPV1 continues (4). Although the national PEI has taken steps to improve the quality of supplementary immunization activities (SIAs),* significant numbers of children living in accessible areas are still being missed during SIAs, and routine immunization services remain suboptimal in many parts of the country. This report describes polio eradication activities and progress in Afghanistan during January 2015‒August 2016 and updates previous reports (5,6). During 2015, a total of 20 WPV1 cases were reported in Afghanistan, compared with 28 cases in 2014; eight cases were reported during January‒August 2016, compared with nine cases reported during the same period in 2015. To achieve interruption of poliovirus transmission in Afghanistan, it is important that the 2016-2017 National Emergency Action Plan† for polio eradication be systematically implemented, including 1) improving the quality of SIAs and routine immunization services, 2) ensuring ongoing dialogue between PEI leaders and local authorities, 3) adopting innovative strategies for reaching children in security-compromised and inaccessible areas, and 4) strengthening cross-border coordination of polio vaccination and surveillance activities with Pakistan.
Cost of antimicrobial drugs in a hospital
Authors: H. A. Reimann
Journal: JAMA (1968)

<h3>To the Editor:—</h3> A report published in 1966 listed what patients paid for antimicrobial drugs in a number of hospitals. In one 550-bed hospital, the cost to inpatients for one month was $15,273 or about $183,000 per year.<sup>1</sup>For the year 1967-1968, the cost had more than doubled to about $400,000, which accounted for 60% of the total bill for all drugs. The Table lists the percentages of the usual "mark-up" prices for various antimicrobial drugs dispensed last year by the hospital pharmacy. Antimicrobial usage increased despite admonition of numerous authorities for restraint in a therapy because of a rising incidence of iatrogenic sequels and of resistant microbes. Penicillin, still prescribed most often, was far exceeded in cost by cephalothin sodium and ampicillin sodium (Table). More ampicillin than cephalothin was dispensed, but the cost of cephalothin, which has no particular advantage over other agents,<sup>2</sup>was more than threefold
The Men from U. C. L. A.
Authors: E. J. H.
Journal: Annals of Internal Medicine (1966)

Editorials1 January 1966The Men from U. C. L. A.E. J. H.E. J. H.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-1-216 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe population center of the United States now lies somewhere in the prairies. Many years have passed since we were a nation of eccentric Anglo-Saxons confined to the Atlantic watershed of the Appalachians. The center of medical gravity, too, has shifted westward. Dr. Irvine Page (1), for one, will agree that in these days the medical muses do not all receive their mail in ZIP zones 02101 to 02193. Without choosing a fulcrum, we must note that Boston, Baltimore, and assorted satellites are balanced by schools of great substance between San Diego and Seattle.Among the fine schools west of...References1. PAGE IH: Editorial: Humbug in the humble hub. Modern Med. October 11, 1965, p. 137. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 January 1966Volume 64, Issue 1Page: 216-216 ePublished: 1 December 2008 Issue Published: 1 January 1966 PDF downloadLoading ...
Pneumothorax During Surgery
Authors: Jack Moyers
Journal: JAMA (1967)

<h3>To the Editor:—</h3> We are delighted to receive Dr. Gilbert's comments and questions; the success of this new series will be enhanced by such inquiry and response. The decision to continue or discontinue operative treatment of the patient following relief of the pneumothorax was obviously a matter of judgment. Our decision to continue was based on the following: The initial incision and dissection had been fashioned to accommodate both tracheostomy and definitive surgery and was not for a simple tracheostomy. After treatment of the pneumothorax, the patient appeared to be in satisfactory condition, and the considered opinion of those present was that further surgery did not constitute more risk than would a second induction of anesthesia and surgery at a later date. It was also the opinion of the surgeons involved that better cancer therapy was offered by doing operations in one stage rather than two. The decision to continue
Erratum: Reassessing the Safety Concerns of Utilizing Blood Donations from Patients with Hemochromatosis
Authors: Adam C. Winters, Douglas Tremblay, Suzanne Arinsburg, John Mascarenhas, Thomas D. Schiano
Journal: Hepatology (2017)

Hereditary hemochromatosis (HH) is a genetic disorder of iron metabolism that may lead to iron overload. Clinical penetrance is low, however those afflicted may develop cirrhosis, hepatocellular carcinoma, diabetes mellitus, and cardiomyopathy. Treatment of HH involves regular phlebotomy to reduce the systemic iron burden. In many countries—including the United States—numerous blood centers do not accept donated blood obtained from HH patients during therapeutic phlebotomy and there are inconsistent positions regarding this globally. This refusal of blood is borne out of a few concerns. First, there is a theoretical increase in the infectious risk of these blood products, particularly by siderophilic organisms such as Yersinia enterocolitica. Second, given the increased incidence of hepatitis C infection from nonvoluntary donors in the 1970s, there is a concern that blood units from HH donors may harbor additional risk given the nonvoluntary nature of their presentation. In this review, we examine the existing biological and clinical data concerning infectious risk and summarize clinical experience from centers allowing HH donors, and demonstrate that blood from HH patients is safe and should be allowed into the donor pool. We conclude that there is no convincing evidence to exclude this population from serving as blood donors. (Hepatology 2018;67:1150–1157)
Heat-Related Deaths—United States, 1993
Journal: JAMA (1993)

From July 1 through July 13, 1993, the heat wave in the eastern United States has been implicated as the direct cause of or a contributing factor to 84 deaths among persons residing in the Philadelphia area. In Philadelphia County, the medical examiner (ME) lists hyperthermia as a contributing factor leading to death if a decedent is elderly or infirm and was exposed to a hot environment. However, reporting of hyperthermia on a death certificate depends on the criteria of individual MEs or coroners. This article describes three case reports of heat-related deaths in other parts of the United States in 1993, summarizes risk factors for this problem, and reviews measures to prevent heat-related illness.
Blood money
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Clinical variables associated with overall survival in metastatic castration resistant prostate cancer (mCRPC) patients treated with sipuleucel-T immunotherapy.
Authors: Xiao Wei, Jaselle Perry, Emily Chang, Li Zhang, Robert A. Hiatt, Lawrence Fong
Journal: Journal of Clinical Oncology (2017)

e16565 Background: Sipuleucel-T (Sip-T) is a cellular-based cancer immunotherapy for men with asymptomatic or minimally symptomatic mCRPC. Its approval was based on overall survival (OS) benefit in randomized placebo-controlled phase 3 trials. However, treatment was associated with PSA decline in only a small minority of pts. Understanding clinical factors predictive of OS may help to guide treatment decisions, including pt selection and timing of Sip-T relative to other therapies. Methods: This is a retrospective chart review of mCRPC pts treated with Sip-T at UCSF between April 2010 and April 2016. All pts completed 3 Sip-T infusions. Patients with localized prostate cancer treated with neoadjuvant Sip-T (NCT00715104) and pts with mCRPC treated with an ongoing phase 2 Sip-T/Ipilimumab trial (NCT01804465) were excluded. Kaplan-Meier method was used to estimate OS. The predictive value of candidate variables – including age, ECOG performance status (PS), Gleason score, metastatic volume, baseline PSA, baseline PSADT, prior abiraterone or enzalutamide, and prior chemotherapy – was assessed using univariate and multivariate Cox proportional hazard model. Results: Of 43 patients evaluated to date, 74.4% had ECOG PS 0, 88.4% had bone +/- nodal metastasis, 81.4% had low metastatic volume, 9.3% had prior abiraterone, 2.3% had prior enzalutamide, and 9.3% had prior chemotherapy. The median age was 69 years (range 53-85), median baseline PSA was 8.3 ng/mL (range 0.05-227.9) and median PSA doubling time (PSADT) was 3.9 mo (range 1.4-15.1). At a median follow-up of 21.4 mo, the median OS was 34.1 mo (95% CI 25.7-41.4). Univariate analysis showed that ECOG PS (HR 6.66, p &lt; 0.001) and PSA (log-transformed) (HR 3.36, p = 0.002) were significantly associated with OS. There was a trend towards worse OS with faster baseline PSADT (log-transformed) (HR 0.16, p = 0.11) and prior chemotherapy (HR = 4.13, p = 0.11). By multivariate analysis, ECOG PS, baseline PSA and baseline PSADT were statistically significant (p &lt; 0.05). Conclusions: In this ongoing retrospective cohort, ECOG PS, baseline PSA and baseline PSADT were associated with OS in mCRPC patients treated with Sip-T.
Medizinische Anwendungen der Elektrizität von M. U. Dr. S. Jellinek.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Occupational Medicine
Authors: Jermyn F. McCahan
Journal: JAMA (1980)

<h3>Occupational Safety and Health Act</h3> Frustrations and conflicting views of priorities in occupational medicine characterize the past decade. The Occupational Safety and Health Act (OSHAct) of 1970 set the stage for much of the turmoil that evolved, and it affected an estimated 60 million employees in approximately 5 million establishments. The Department of Labor under the OSHAct was charged with the responsibilities of setting standards and enforcing them; the Occupational Safety and Health Administration (OSHA) was created for this purpose. The then Department of Health, Education, and Welfare (DHEW) inherited new tasks in safety and health research, training, and employee education. The federal courts were granted jurisdiction in enforcement proceedings brought under the act. For all employers throughout the country, there were problems in determining what the act required and how they could remain in compliance. New agencies were created to perform specific functions. The Occupational Safety and Health Review
News and Notices
Journal: British Journal of Dermatology (2015)

British Journal of DermatologyVolume 172, Issue 6 p. 1689-1689 News and Notices News and Notices First published: 02 June 2015 https://doi.org/10.1111/bjd.13891Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume172, Issue6June 2015Pages 1689-1689 RelatedInformation
Sublethal exposure to microwave radar
Authors: Samuel A. Forman
Journal: JAMA (1988)

<h3>To the Editor.</h3> —I read with interest the letter by Drs Castillo and Quencer<sup>1</sup>that describes a 42-year-old man with coagulation necrosis of the vallecula and the sternocleidomastoid muscle and psychological symptoms following short-term exposure to microwave radar. The case report describes accidental exposure for five minutes to military radar. There are no data concerning the wavelength, pulse characteristics, and field intensity of the radar source. Just as we expect a case report of a drug overdose to state the pharmacologic agent, the dose, and the route of entry, an adequate description of an environmental microwave exposure includes wavelength, source characteristics (continuous or intermittent), and field intensity. Microwave field intensity is described by both electric field strength (volts per minute) and power density (milliwatts per square centimeter). Microwaves encompass a range of electromagnetic nonionizing radiation whose energy levels and tissue penetration depend on wavelength. All radar systems, microwave ovens,
The Use of Protein Adducts to Investigate the Disposition of Reactive Metabolites of Benzene
Authors: S. M. Rappaport, T. A. McDonald, K. Yeowell-O'Connell
Journal: Environmental Health Perspectives (1996)

Benzene is metabolized to a number of electrophilic species that are capable of binding to both DNA and proteins.We used adducts of hemoglobin (Hb) and bone marrow proteins to study the disposition of three benzene metabolites (benzene oxide [BO], 1,2-benzoquinone [1,2-BQI, and 1,4-benzoquinone [1,4-BQO) in F344 rats and B6C3F1 mice following a single oral dosage of [13C6lbenzene and/or [14C]benzene.Our assays focused upon cysteine adducts that accounted for 38 to 45% of protein binding to Hb and 63 to 81 % of protein binding to bone marrow.Although both mice and rats showed dose-related increases in Hb and bone marrow protein adducts of BO and of the two benzoquinones, large intertissue and interspecies differences were noted, suggesting different preferences in metabolic pathways.The highest levels of adducts in mice were of 1,4-BQ (10-27% of all cysteine adducts), while in rats, BO adducts predominated in Hb (73% of all cysteine adducts) and 1,2-BQ adducts predominated in the bone marrow (14% of all cysteine adducts).High background levels of 1,2-BO and 1,4-BQ adducts were also detected in both species, indicating that the toxic effects of quinone metabolites may only be important at high levels of benzene exposure.