tbuckley/cabot-search huggingface dataset:
William T.G. Morton (1819-1868), demonstrator of ether anesthesia
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chest pain in users of video display terminals
Authors: T. M. Schnorr
Journal: JAMA (1987)

<h3>To the Editor.—</h3> Haynes<sup>1,2</sup>and LaCroix<sup>3</sup>have reported that office workers who used video display terminals (VDTs) experienced a fourfold increase in angina pectoris compared with nonusers. These findings were reported to the membership of the union that requested the study,<sup>4</sup>but are as yet unpublished in a peer-reviewed forum. The resulting publicity (<i>Washington Post</i>, Jan 31, 1985) linking VDTs to cardiovascular morbidity has caused concern among office workers as well as skepticism in the scientific community. Public concern over potential cardiac hazards of VDT exposure joins other health concerns associated with VDT use, such as visual/musculoskeletal disturbances and reproductive effects.<sup>5</sup> The Communications Workers ofAmerica, the union representing the study population, requested that we further investigate this excessively high frequency of reported chest pain. We first attempted to confirm the reported excess by reanalyzing the data provided to us by the union.<sup>6</sup> We found
Horses, Women and Children
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Emergency management of the obstructed airway
Authors: D. S. Gann
Journal: JAMA (1980)

THE REPORT to the American Red Cross on emergency management of the obstructed airway by the Committee on Emergency Medical Services (EMS) of the National Academy of Sciences (NAS) has been challenged. Specifically, Henry Heimlich, MD, and Edward A. Patrick, MD, charge that, in the sequence of maneuvers recommended by the NAS, ie, rapid and vigorous backslaps followed by manual thrusts, the backslaps can drive an object deeper into the throat and thus cause death.<sup>1-3</sup>Dr Heimlich contends that only the manual thrusts should be used. Since disagreement has resulted in confusion in the minds of the medical profession as well as the public, it seems appropriate to present a summary of the basis for the committee's recommendations. It must be understood that the disagreement is of a type that frequently occurs in science when data are inadequate to definitively prove or disprove strongly held opinions on an issue,
Efficacy of eplerenone (Epe) in the management of mineralocorticoid excess (MCE) in men with metastatic castration-resistant prostate cancer (mCRPC) treated with abiraterone (AA) without prednisone (P).
Authors: David Michael Gill, David Gaston, Andrew W. Hahn, Erin B. Bailey, Tyler Howard Buckley, Eric Johnson, Julia A. Batten, Anitha Alex, Kenneth M. Boucher, David D. Stenehjem, Neeraj Agarwal
Journal: Journal of Clinical Oncology (2017)

261 Background: AA is approved for Mcrpc with co-administration with P to prevent MCE toxicity such as hypertension, hypokalemia and edema. However, use of P is often not desirable by the relatively asymptomatic patients because of potential for detrimental effects of long term corticosteroid therapy. Epe is a non-steroidal mineralocorticoid antagonist demonstrated to abrogate MCE. Here we report real world experience of use of Epe with AA in men with mCRPC who wished to avoid concomitant P. Methods: Incidence and grade (CTCAE v4) of MCE, along with baseline demographics, disease characteristics, and progression free survival (PFS) in men with mCRPC treated with AA (1000 mg daily), not willing to be treated with P (and thus received treatment with Epe 50 mg daily) were collected retrospectively, and compared with those treated with AA + P (10 mg daily) during the same time period (Table). Continuous variables were assessed by Wilcoxon rank sum or student t-test, and categorical variables were assessed by Fischer’s Exact test or chi-square as appropriate. PFS was compared by Kaplan-Meier. Results: Baseline and disease characteristics, median PFS, and toxicities of all grades were similar in both cohorts (Table). Conclusions: In real world population of men with mCRPC treated with AA, corticosteroids may be avoided by concomitant treatment with Epe. Data need further validation in a larger cohort. [Table: see text]
Migration of plasticizer from hemodialysis blood tubing. Preliminary report
Authors: K. Ono
Journal: JAMA (1975)

Di-2-ethylhexyl phthalate was found to be migrating from polyvinyl chloride blood tubing into human blood during hemodialysis in 16 patients with end-stage renal failure. Although toxic effects have not yet been observed, we believe plastic tubing that does not contain extractable materials should be developed. (<i>JAMA</i>234:948-949, 1975)
Masthead: (Adv. Healthcare Mater. 13/2016)
Journal: Advanced Healthcare Materials (2016)

Citizenship: Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have focused on sharing our content with those in need, enhancing community philanthropy, reducing our carbon impact, creating global guidelines and best practices for paper use, establishing a vendor code of ethics, and engaging our colleagues and other stakeholders in our efforts.
Abstract 59: New findings implicated in Coronary calcification in Chronic phase Kawasaki disease
Authors: Tomoyo Yahata, Kazuyuki Ikeda, Akiko Hamaoka, Chinatsu Suzuki, Ayako Yoshioka, Yuki Kuchitsu, Kenji Hamaoka
Journal: Circulation (2015)

Background: Kawasaki disease (KD) is a systemic vasculitis prevalent in infants and sometimes complicates coronary artery lesions (CALs). It has been well known that CALs gradually develop endothelial dysfunction, post-inflammatory arteriosclerotic changes, and finally coronary calcification. It has been also reported, recently, that vascular calcification is an active cell-driven process characterized by osteogenic differentiation of vascular smooth muscle cells, relating to the chronic inflammation and oxidative stress. In this study, in KD, we evaluated the possible implication of significant calcification prevalent in CALs to the long-term prognosis. Methods: We included 42 patients with a history of KD (age:18.3±6.7 year-old). The breakdown was 17 patients without CALs and 25 with CALs; 12 without calcification and 13 with calcification on multi-detector computed tomography. We measured %FMD as an endothelial function marker and hs-CRPs as an inflammatory marker, serum hydroperoxide and urinary 8-OHdG as oxidative stress markers, and the bone mineral density (BMD). Patients in CALs(-) group took no medicine and those in CALs(+) group were under antiplatelet and/or anticoagulant therapy, particularly, those with calcification were additionally administrated statin or ARB. Results: Values of %FMD in CALs(+) group were significantly lower compared with those in CALs(-) (p&lt;0.05), and values in those with calcification were still lower than those without calcification (p&lt;0.05). Values of hs-CRPs in CALs(+) group were significantly lower than those in CALs (p&lt;0.05). 8-OHdG values as oxidative stress marker in CALs(+) group were significantly lower than those in CALs(-) (p&lt;0.05). The BMD in CALs(+) group tended to be lower compared with the age-matched reference values (88.9±7.0% of normal). Conclusions: In KD chronic stage, the decreased %FMD may be an essential condition to occur coronary calcification. Decreased BMD in patients with coronary calcification suggested the possible existence of the skeletal and the vascular system in KD, similar to the mechanism of common vascular calcification.
Freon and hypertension
Authors: W. E. Morton
Journal: JAMA (1992)

<h3>In Reply.</h3> —Drs Davis and Samet make an appropriate point regarding the need to determine if there is a reduced risk in former smokers as compared with current smokers. We chose to report smoking status as reported at the time of HIV serologic testing when we asked only if patients had ever smoked. A potential problem with the analyses proposed by Davis and Samet is the uncertain time of HIV infection. The HIV infection could have occurred before a smoker's quitting, thus diluting any association between smoking status and HIV infection. Prospective cohort studies of women at risk would be the best way to evaluate this association and any possible decrease in risk following cessation of smoking. As implied by Drs Phillips and Davey Smith, unprotected sexual intercourse with an HIV-infected man is undoubtedly the key factor in the acquisition of HIV infection in women. Our detailed histories of sexual
Allergic Pruritus: Its Dermatologic Management.
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of the male partner of an infertile couple. An algorithmic approach
Authors: R. S. Swerdloff
Journal: JAMA (1982)

THE FIRST and most important rule in the evaluation of infertility is to consider the problem from the standpoint of both members of the couple. Too often a woman is extensively investigated only to discover later that her husband is azoospermic, and, likewise, a man undergoes lengthy treatment for oligospermia while his wife has undiagnosed tubal obstruction or has anovulatory cycles. The evaluation of both the man and woman should proceed in parallel until a significant problem is uncovered. Ideal management is attained in a clinical setting where the couple is seen by a team of physicians. In the usual case, where the man is under the care of either an endocrinologist or a urologist and the woman is under the care of a gynecologist, communication between physicians must be ongoing. The male partner should undergo a complete history and physical examination with special emphasis on the reproductive system. The
Guidelines for development of new health occupations
Authors: T. C. Points
Journal: JAMA (1970)

One approach to increasing the supply of health services is rational delegation of some of the physician's traditional functions in delivery of health care. Such an approach involves reallocating duties between the physician and other health personnel to achieve the best use of skills at each level, and often results in reducing the time input in education required to perform a given health service. This reallocation of duties can take place in two ways: by expanding the medical service role of existing health occupations, or by creating and recruiting for new career roles to assist the physician. Neither of these methods is in itself new. Physicians have been delegating tasks to allied workers and training their own "assistants" for many years. Many physicians, within their office settings, have been highly successful in training persons to perform specific functions previously associated solely with the physician's role. The duties of these assistants
Cocaine
Authors: Sid Schnoll
Journal: JAMA (1975)

<h3>To the Editor.—</h3> The article by Dr. Sidney Cohen (231:74, 1975) on cocaine certainly is important. There has been a great upsurge in the use of this drug. However, Dr. Cohen fails to talk about one of the important patterns of abuse most likely to be seen by the physician. Cocaine is being used by people who often abuse other drugs, but is, in fact, used infrequently by this group because of its expense. On the other hand, there has been a large increase in the use of cocaine by young, middle-class professionals. This latter group is made up of fairly affluent people, usually in their early to mid-30s; previous experience with drugs has been limited to marihuana and the occasional use of an hallucinogen. Cocaine has recently become a very fashionable drug with these people. Large quantities are usually found at parties, and one way of displaying one's wealth
NEWS AND NOTES
Journal: British Journal of Dermatology (1967)

British Journal of DermatologyVolume 79, Issue 1 p. 72-72 NEWS AND NOTES First published: January 1967 https://doi.org/10.1111/j.1365-2133.1967.tb11404.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume79, Issue1January 1967Pages 72-72 RelatedInformation
<i>Circulation</i> : Clinical Summaries
Journal: Circulation (2015)

Fibrillation and Valvular Heart Disease: Findings From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) TrialThe coexistence of atrial fibrillation and valvular heart disease (VHD) is associated with a higher risk of thromboembolic events and bleeding.There is a lack of available data evaluating new oral anticoagulants in patients with VHD and atrial fibrillation.We compared the effect of apixaban and warfarin on rates of stroke or systemic embolism, major bleeding, and death in 4808 patients with and without moderate or severe VHD, from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) study.Apixaban, in comparison with warfarin, had similar relative and larger absolute benefits in reducing stroke or systemic embolism, causing less bleeding, and reducing mortality in patients with VHD in comparison with those without VHD.The current analysis provides a reliable evaluation of the efficacy and safety of apixaban in patients with VHD, and the results will potentially improve the cardiovascular burden of atrial fibrillation in VHD.See p 624.
Unspecified reform tops agenda
Authors: P. Cotton
Journal: JAMA (1993)

THOSE WHO SAY managed competition is the wave of the future like to count newly inaugurated President Bill Clinton as one of their own. However, the new President, while repeatedly saying that health care reform is at the top of his agenda, has made no commitments on how to do it. Clinton has said he leans toward a market-based approach like managed competition. This new buzzword describes proposals in which health insurance purchasing cooperatives would broker and referee insurance coverage, with the goal of giving everyone the benefit of large-group rates while trying to promote competition among networks of health care providers. These purchasing cooperatives in theory would promote improved quality and lowered costs by rewarding those insurance plans with the best quality and lowest costs with more subscribers (<i>JAMA</i>. 1991;265:2532-2536). Most versions of such a plan also call for taxing health insurance benefits that go beyond a "basic" level
1933 DUES PAYABLE
Journal: JAMA (1933)

Several weeks ago, the bills for 1933 dues were mailed to each Fellow and subscriber ofThe Journal. The readiness with which payments have been made is not only gratifying but significant. The number of remittances received actually exceeds those of last year at this time, a fact which indicates the esteem in which physicians hold Fellowship in the Association and the value they attach toThe Journal. For the convenience of those who have not yet paid their 1933 dues, a colored slip is enclosed in this issue. It is a statement, cut in such a form and glued so that when folded a convenient "business reply" envelop is formed, requiring no addressing nor stamps. ThatThe Journalwill be as vitally necessary to the physician during the coming year as during the past is indicated by the fact that already more than a hundred articles of great importance
Shut its Doors and Closed its Blinds.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Terminating the physician-patient relationship in primary care
Authors: R. B. Freidin
Journal: JAMA (1979)

Primary care and family practice training programs stress the importance of establishing and maintaining the physician-patient relationship in providing longitudinal health care. However, the limited duration of these three-year programs builds discontinuity into the relationship. To our knowledge, the process of terminating the physician-patient relationship in primary care practice has not been addressed in the medical literature. We studied eight different patterns of patients' responses to learning of the departure of their primary care physicians. We have developed a set of guidelines for terminating the physician-patient relationship in an ambulatory, primary care setting. (<i>JAMA</i>241:819-822, 1979)
Left Atrial Mural Thrombus Secondary to Transseptal Left Heart Catheterization
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
More drug trials end early hiding potential problems
Journal: BMJ (2005)

experts agree that the obesity epidemic is environmental, but the research has largely ignored this factor. 24It is time to be realistic with individuals about the limited effectiveness of lifestyle interventions and obesity drugs, and to focus on public health interventions rather than individual treatments to halt the obesity epidemic.This article is based on the monograph "What works for obesity?A summary of the evidence behind obesity interventions," which was published in association with Clinical Evidence by the BMJ Publishing Group and commissioned, funded, and distributed by the United Health Foundation..I thank Matt M Davis and Boyd Swinburn for reviewing earlier versions of this manuscript and offering helpful comments.