tbuckley/cabot-search huggingface dataset:
Les thérapeutiques nouvelles: Exposé critique et synthétique applications.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Native American Physician Incorporates Tradition Into Mainstream Medical Care
Authors: L. Lamberg
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Future Research Needs Associated with the Assessment of Potential Human Health Risks from Exposure to Toxic Ambient Air Pollutants
Authors: Lennart Moller, Dennis Schuetzle, Herman Autrup
Journal: Environmental Health Perspectives (1994)

This paper presents key conclusions and future research needs from a Workshop on the Risk Assessment of Urban Air, Emissions, Exposure, Risk Identification, and Quantification, which was held in Stockholm during June 1992 by 41 participants from 13 countries.Research is recommended in the areas of identification and quantification of toxics in source emissions and ambient air, atmospheric transport and chemistry, exposure level assessment, the development of improved in vitro bioassays, biomarker development, the development of more accurate epidemiological methodologies, and risk quantification techniques.Studies are described that will be necessary to assess and reduce the level of uncertainties associated with each step of the risk assessment process.International collaborative research efforts between industry and government organizations are rec- ommended as the most effective way to carry out this research.-
Editorial Board
Authors: Donald Leung, Stanley Szefler, Colo Associate, Cezmi Akdis, Davos Switzerland, Andrea Apter, Pedro Philadelphia, Chicago Avila, Bruce Bochner, Joshua Boyce, David Broide, M Chb, La Jolla, Robert Calif, Madison Bush, Fred Finkelman, Dennis Ledford, Tampa Fla, Deborah Meyers, David Peden, Marc Rothenberg, Cincinnati Ohio, William Shearer, Scott Sicherer, New York, Donata Vercelli, Erika Von Mutius, Statistics Editor, Vernon Chinchilli
Journal: Journal of Allergy and Clinical Immunology (2011)
How representative are the weights of insured men and women?
Authors: C. C. Seltzer
Journal: JAMA (1967)

The weights of insured persons are not representative of the weights of the general population; they appear to be appreciably lower. This is particularly marked in the case of women. The trend toward decreasing weight in insured women is contrary to the actual trend toward increasing weight of women in the general American population. The reason for these differences may be sought in part in the self-selection of persons applying for insurance under ordinary policies, and in part in the selective process applied by life insurance companies in the issuance of these policies.
THE GLUCOSE CONTENT OF NORMAL URINE
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Why Are On-the-Job Fatalities So High Among Oil and Gas Industry Workers?
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 5100: Optimization of amplicon design for polymerase chain reaction
Authors: Bolong He, Hao Qin, Fugen Li, Hanyan Yang
Journal: Cancer Research (2019)

Abstract Amplicon design is critical important in DNA sequencing technology. Previously the amplicon designer uses exhaustive trial and error method, relying on the individual experience to compare the cost of different amplicon combinations. However, optimization of amplicon design has remained challenging due to the lack of a systematic method. As the magnitude of target DNA region and amplicon combination increases, the complexity of manual calculation and judgment will grow exponentially. In this study, our aim was to design a mathematical model to minimize the cost of amplicon combination. For given amplicon design problem, a linear integer programming model is constructed according to the optimization target and the restrictions. Let’s denote our target regions by R_1⋯ R_M, and amplicon by A_1,⋯, A_N, and conflict value c_ij for the amplicon pair A_i and A_j. The model’s restriction is to find a set of amplicons that could cover the target regions as much as possible, and for each R_i we have at most two A_j which will cover it simultaneously. The model’s optimization target is to minimize the total conflict value. The model is implemented by Python programming and uses Gurobi optimization software. In a project to design amplicon for DNA sequencing, the target regions consist of about 90,000 bits, and there are about 35,000 amplicon available. The above optimization method running on the personal computer with 8GB and 2.2GHz Intel i5-5200 CPU, take about 24 hours and produce total conflict value of 1374. The best trial and error practice took more than one week and produced total conflict value of 4527. Optimization of amplicon design for polymerase chain reaction proves to be more precise and efficient than the exhaustive trial and error method. Using optimization method will help standardize the product design for DNA sequencing. Citation Format: Bolong He, Hao Qin, Fugen Li, Hanyan Yang. Optimization of amplicon design for polymerase chain reaction [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 5100.
Methadyl acetate and methadone. An open comparison
Authors: E. C. Senay
Journal: JAMA (1977)

Heroin addicts were recruited for a 14-week open clinical comparison of methadone hydrochloride and methadyl acetate. Patients were randomly assigned to a methadyl acetate clinic in which methadyl acetate was dispensed to patients three times per week or to a methadone clinic in which methadone was dispensed six days per week. No statistically significant differences were observed between groups in retention rates, illicit drug use, employment rates, or arrest rates. The group treated with methadyl acetate had more dropouts in the first seven weeks than the second seven weeks: this pattern was reversed for the methadone-treated group. The differences were significant (<i>P</i>=.01). Spontaneously reported symptoms suggest that induction with methadyl acetate may be a more clinically variable phenomenon than induction with methadone. The reduction of number of clinic visits in the group treated with methadyl acetate was not a source of variance in treatment effectiveness. (<i>JAMA</i>237:138-142, 1977)
Cardiac Auscultation Skills of Physicians in Training
Authors: Wolffe Nadoolman
Journal: JAMA (1997)

<h3>To the Editor.</h3> —While I strongly believe that cardiac auscultation is a skill worth honing, I disagree with the conclusions of Drs Mangione and Nieman<sup>1</sup>that a deficiency in the skills they tested might be a serious problem and that board-certification examinations for primary care specialties should include evaluation of these skills. Any physician practicing rural medicine or who has visited Third World physicians knows the value of keen physical examination skills—especially auscultation. However, where most physicians in the United States practice, the rules are different. While this study examined the ability of residents to identify specific cardiac sounds, it did not show what proportion of those residents tested either did not notice any abnormality or did not generally recognize a pathologic sound. This ability to identify the presence of an abnormality is much more important that the ability to identify what the abnormality is. Even presuming the auscultation
Renal Damage Associated with Chronic Phenacetin Overdosage
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"FOUND: A ONE DAY CURE FOR SYPHILIS"
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Utilization of the Posterior Sinus of Valsalva for the Creation of a Third Coronary Artery
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical pests
Authors: J. R. Harnes
Journal: JAMA (1976)

RECENTLY, a group exchanged our personal experiences with zealots intent on converting us to their religions. We understood their motivation and admired their devotion to their church and its tenets. Nevertheless, we agreed that when such individuals persisted in conversion attempts in the face of polite but firm disinterest, they became pests. Later, I read that some physicians were proposing that doctors who smoke cigarettes should lose their hospital privileges and perhaps their licenses to practice medicine. I realized then that physician proselytizers, like religious proselytizers, were pests. Like the religious zealot, the medical zealot refuses to admit that others are aware of his or her beliefs. The zealot also refuses to admit that others may have weighed the pros and cons of conversion and have decided to risk damnation by continuing their sinful ways. Smoking, lack of exercise, and high-fat diets are the major targets of our current medical
Sixth Integrated Latin-American Congresses of Cancerology
Journal: JNCI Journal of the National Cancer Institute (1975)

Sixth Integrated Latin-American Congresses of Cancerology Get access JNCI: Journal of the National Cancer Institute, Volume 54, Issue 6, June 1975, Page 1498, https://doi.org/10.1093/jnci/54.6.1498c Published: 01 June 1975
Diagnosis of Intra-amniotic Infection by Proteomic Profiling and Identification of Novel Biomarkers
Authors: Carmela Balistreri, Giuseppina Candore, Giuseppina Colonna-Romano, Domenico Lio, Marco Caruso, Enrico Hoffmann, Calogero Caruso
Journal: JAMA (2004)

PϽ.001), with intermediate values in healthy young controls (TABLE).After adjustment for risk factors, significant differences in SNP frequency persisted between patients with AMI and oldest old men (P=.002) and between young controls and oldest old controls (PϽ.001).Comment.Some studies have shown that individuals with the Asp299Gly TLR4 SNP have a lower risk of atherosclerosis and a decreased risk of acute coronary events independent of the standard coronary risk factors.However, discordant results have been reported.The causes of the discrepancies are not clear, but the inclusion criteria, the study populations, and the measured end point differed substantially among the studies. 3,5However, our results support a role of the innate immune defense system and particularly TLR4 in CVD.These results fit well with a recent study supporting a role of TLR4 in atherogenesis 3 and with the largest epidemiologic evaluation so far, 6 which showed lower levels of C-reactive protein with concomitant reduction in risk of coronary artery disease in patients carrying the studied SNP.Our comparison with the oldest old may help elucidate the role of genetics in age-associated diseases characterized by a multifactorial etiology.Finally, TLR4 polymorphisms, which attenuate receptor signaling, enhance the risk of infections 5 but decrease that of atherogenesis, presumably by limiting inflammatory responses.Hence, the mutation might result in an increased chance of longevity in a modern environment with reduced pathogen load and improved control of severe infections by antibiotics.
Endemic pleural calcification and mesothelioma
Authors: A. M. Langer
Journal: JAMA (1988)

<h3>To the Editor.—</h3> A recent case report by Sichletidis et al<sup>1</sup>and a letter on the case by Dr Germine<sup>2</sup>merit comment. In 1985, we reported the occurrence of endemic pleural calcification and mesothelioma in northwestern Greece.<sup>3</sup>Although an earlier report had described widespread pleural calcification observed during a tuberculosis survey in the region, we found that mesothelioma had occurred as well.<sup>3</sup>No occupational or infectious agent could be found to explain this pattern, referred to as<i>Metsovo lung</i>. The number of pleural mesotheliomas observed, five among 5000 people in two years, was striking considering there was no commercial asbestos industry within 80 km of the area. We reported that asbestiform tremolite was found in five of the eight transbronchial biopsy specimens obtained from people with Metsovo lung. We suggested that this was the agent responsible for both Metsovo lung and the pleural mesotheliomas, although the
Preoperative Screening for Sickle Cell Trait
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: BMJ (1963)

The occurrence of autoantibodies in infectious hepatitis may be an example of autoantibody formation following intracellular infection (Davis, 1944).The patient with thymoma and aplastic anaemia who gave a positive antinuclear factor test was of particular interest.The association of thymoma with myasthenia gravis in which antibodies to muscle occur (Strauss, Seegal, Hsu, Burkholder, Nastuk, and Osserman, 1960) suggests that the thymus may play a part in autoimmune disease.The occurrence of antinuclear factor in a patient with thymoma provides circumstantial evidence for this view.Hijmans et al. ( 1961) and others have shown that anti- nuclear factor is nearly always present in systemic lupus erythematosus.Our finding that it is usually absent in blood and liver disorders underlines the value of the antinuclear factor test in the diagnosis of systemic lupus erythematosus. SummaryTests for antibodies commonly associated with autoimmune disease were carried out on sera from patients with blood and liver disorders.Antinuclear factor was definitely present in one case of scleroderma with agranulocytosis, one case of thymoma with aplastic anaemia, and one case of infectious mononucleosis.Complement-fixing antibodies against rat liver and kidney were significantly raised in 7 of the 13 patients with infectious hepatitis and in two of the seven patients with glandular fever.The latex test for rheumatoid factor was positive in 10 of the 22 patients with liver disease.We would like to thank the consultants of Guy's Hospital and Dr. C. W. H. Havard and Dr. R.