tbuckley/cabot-search huggingface dataset:
Hypereosinophilic Syndrome
Authors: T Ishizuka, M Mori
Journal: New England Journal of Medicine (2000)

The article focuses on one of rarely occuring forms of "major eosinophilias"--hypereosinophilic syndrome (HES). Based on two observations and data from the published literature the clinical presentation of HES is described together with affection of different organs, changes in the blood and bone marrow. The article has a particular focus on differential diagnosis of HES, symptomatic and clonal eosinophilias, importance of cytogenetic investigations. The policy of managing patients presenting with the above medical problem is discussed.
THE OPEN-AIR TREATMENT OF PULMONARY TUBERCULOSIS.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pregnancy, Fitness, and Sports
Authors: Evalyn S. Gendel
Journal: JAMA (1967)

The premise of this communication is that lack of physical activity and sports since childhood —leading to underdeveloped, poor tone abdominal musculature, and weak fascial tissue—is a major contributing factor in chronic, severe, low backache following pregnancy in a group of young women. A group of patients 18 to 23 years of age was studied and followed during a period of 1 1/2 to 5 years. All of the patients were seen by the same physician. Most were supervised throughout pregnancy and the postpartal period. Others, whose babies had been delivered elsewhere, came as patients when they moved into the area. The clinical impression of these patients was compiled into a composite case history for study. Members of the Maternal Welfare Committee of the State Medical Society, board-certified obstetricians and gynecologists, and general practitioners limiting their practices to obstetrics and gynecology were asked for comments on similar findings in their
Oesophagus Posters
Authors: A. Chandra, A. Anggiansah, R. Anggiansah, W.J. Owen
Journal: Gut (2001)

Introduction: Patients who have undergone oesophageal pH studies are re-referred for a variety of reasons, after varying time intervals. The aim was to determine if repeating the pH study was likely to alter the diagnosis. Patients and methods: Data was reviewed from adult patients who were studied
Cardiopulmonary Resuscitation.
Authors: A Pades Jiménez, A M Tomás Vidal
Journal: Annals of Internal Medicine (1983)

Presented is a basic care plan that nurses should put into practice before and after cardiopulmonary resuscitation. Besides the typical resuscitation maneuvers, all health care professionals should know and be able to evaluate the possible complications that could arise so that they can detect them beforehand and plan their prevention. Also explained are details regarding ways to help the patient and his/her family cope with this physical and emotional crisis.
A Comparative Trial of Clotrimazole Troches and Oral Nystatin Suspension in Recipients of Renal Transplants
Authors: Myles E. Gombert
Journal: JAMA (1987)

An open study designed to compare the effectiveness and safety of clotrimazole troches with nystatin oral suspension in the prevention of oropharyngeal candidiasis was conducted. This study was performed as the troche form of clotrimazole was easier to administer and less costly than nystatin oral suspension. Sixty assessable patients were randomized to receive either clotrimazole troches (n = 32) or nystatin oral suspension (n = 28) for a 60-day period after receiving a renal allograft. The two groups were comparable in age, sex, type of transplant, and amount of immunosuppression. Both regimens were 100% effective in preventing the development of thrush in the patients studied. Adverse effects were infrequently seen in either group (one case of mild nausea in the clotrimazole group and three cases in the nystatin group). One patient chose to withdraw from the clotrimazole group, and eight patients withdrew from the nystatin group before completing 60 days of therapy (<i>P</i>=.002). Reasons given for withdrawal were the unpleasant taste of the drugs, or an inability to comply with the protocol. The cost of clotrimazole troches in the prophylactic doses given in this study was approximately one tenth that of nystatin oral suspension. Clotrimazole troches are effective, less expensive, and easier to self-administer than nystatin oral suspension. (<i>JAMA</i>1987;258:2553-2555)
Radiographic Diagnosis of Meckel's Diverticulum
Authors: Sidney M. Wolfe
Journal: JAMA (1968)

<h3>To the Editor.—</h3> Preoperative radiologic diagnosis of Meckel's diverticulum was established in a 21-year-old man with chronic iron deficiency anemia. This was accomplished by passage of a thin polyethylene tube and subsequent injection of colloidal barium sulfate (Microtrast [Britain]). <h3>Report of a Case:—</h3> A 21-year-old white man was admitted to the Clinical Center of the National Institutes of Health for evaluation of long-standing anemia. At 2 or 3 years of age the patient was noted by his mother to be pale and to have frequent attacks of abdominal pain. He tired more easily than his playmates but was otherwise normal. At age 14 the anemia was first documented during evaluation of possible rheumatic fever, and the patient was given a trial on orally administered ferrous sulfate. There was no response to this form of therapy. At age 18 he was admitted to a local hospital for further evaluation of the
Clinical Bacteriology and Haematology for Practitioners.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical Education, Medical Care, and Our Public
Authors: Robert L. Evans
Journal: JAMA (1973)

Frustration and disquiet with medical care is a major symptom of our present culture. The American public has been deluged with information on what fine, crisis-oriented emergency care and the episode-oriented specialty care modern medicine can provide. The public has also experienced the near impossibility of obtaining a third, and less complex care—continuing, comprehensive personal care. At times, some people we serve have not been able to gain access to any nonemergent care, yet provision of all three types of care is clearly within our abilities. Difficulty in provision of such care at acceptable cost has produced three major pressures on our system of health care and medical education. These are (1) pressure for major change in the method, control and amount of third-party payments for health care, coupled with mounting ire toward supporting biomedical research and medical education from the patient care dollar; (2) increasing public and political resistance
Making a Difference in Adolescent Health
Authors: M. Joycelyn Elders
Journal: JAMA (1993)

It has been said that a society is ultimately judged by its attention to its weakest members. While not our weakest, adolescents are perhaps the most vulnerable members of our society, as they make the transition from childhood to adulthood. Adolescence is a period of profound change. More changes take place in anatomy and physiology, mental and emotional functioning, and social development during adolescence than in any other life stage except infancy. The attitudes and behaviors molded during adolescence often determine the life-style and health habits of adulthood, creating long-term health implications. Improving the health status of adolescents is critical to improving the health status of the population. How well are we doing as a society in attending to the health needs of adolescents? Consider the leading mortalities and morbidities of today's youth: Injury and violence account for three of four adolescent deaths.<sup>1</sup> Homicide is the second leading cause of
Ability of toddlers to recognise TV images
Authors: M. Hunter
Journal: BMJ (2000)

Smoking research of the 1950s could be celebrated in UK and US stampsEditor-Tobacco Control reproduced anti-tobacco postage stamps on the covers of its first six issues. [1]2][3][4] By 1992, 43 countries had issued anti-tobacco stamps, 1 and Poland issued an antismoking postcard as far back as 1971.Sixty five countries have now issued anti-tobacco stamps or other postal items.Two of the recent issues are from Libya in 1995 and Romania in 1999 (figures).By contrast, 125 countries have
The History of Malariotherapy for Neurosyphilis
Authors: Stephanie C. Austin
Journal: JAMA (1992)

THE ACQUIRED immunodeficiency syndrome (AIDS) epidemic and the attempt to deregulate drug approval with the goal of hastening a cure have parallels with another sexually transmitted disease and the search for its cure. Syphilis and one of its dread consequences, neurosyphilis, was a disease that consumed much public health concern, and whose putative "cure," malariotherapy, earned the 1927 Nobel Prize in Medicine for the Austrian psychiatrist Julius Wagner-Jauregg. In reviewing the history of syphilis, the true benefits of malariotherapy are unknown because of the research methods used at the time. Was malariotherapy efficacious? This historical question is relevant to the present debate over drug regulations and AIDS, because abandonment of drug evaluation protocols could return us to the methodologic environment of Wagner-Jauregg's day. It seems worthwhile to review the similarities and differences between the two diseases, social climates, and searches for cures. In Europe and the United States at the
Virus Particles in SJL/J Mouse Disease&lt;xref ref-type="fn" rid="FN1"&gt;2&lt;/xref&gt;
Journal: JNCI Journal of the National Cancer Institute (1972)

Lymphatic tissues from 26 strain SJL/J mice, 1–443 days old, were examined electron microscopically. Virus particles were rare in newborn or young mice, which are apparently free from lymphomatous lesions. However, in the lymphatic tissues of animals >313 days old, type-C virus particles were abundant, and lymphoid hyperplasia and reticulum cell neoplasia were seen (Dunn's type-8 lesion). Characteristically, numerous type-C virus particles were localized between irregularly shaped cisternae in the cytoplasm of peculiarly shaped giant cells. Some budding or immature type-C particles, associated with mature type-C particles, were also in the cisternae. These abundant type-C virus particles within the lymph node may be closely related to reticulum cell neoplasia.
Alexis Carrel, the Man Unknown
Authors: Jack Moseley
Journal: JAMA (1980)

MANY American physicians may not realize that their country's first Nobel Prize for Medicine was awarded in 1912, not to an American, but to an expatriated Frenchman for work that he began in France. A look at the enigmatic French physician who started America's tradition of Nobel Prize laurels provides some insight into why his ideas found a place to grow in the United States. Alexis Carrel was born in SainteFoy-les-Lyon, a village in the prosperous Lyon region of France on June 28, 1873. His parents were descendants of well-to-do textile and linen merchants. Although his first name was originally Auguste, he was given his father's first name, Alexis, after the death of his father in 1877, as was a custom for honoring the dead. His mother, forced to raise three small children on a reduced income, turned occasionally to sewing and embroidering with a sewing circle in Lyon. The
Professional Standards Review Organizations: The Current Scene
Authors: Frank W. Sullivan
Journal: American Journal of Psychiatry (1974)

In October 1972, President Nixon signed into law Public Law 92-603, a section of which calls for mandatory utilization review of inpatient medical services rendered to Medicare and Medicaid patients and beneficiaries of Maternal and Child Health programs. This article reviews the law's history, requirements, and means ofimplementation; it also discusses the medical profession's response and activities thus far and the implications of the law for psychiatry.
Firearm Design and Firearm Violence
Authors: Richard J. Feldman
Journal: JAMA (1996)

<h3>To the Editor.</h3> —A product-oriented approach to firearm violence is fraught with pitfalls, as even Dr Wintemute admits,<sup>1</sup>and may indeed result in unintended, counterproductive effects. The banning by policymakers of a product today because of its lethality or perceived prevalence in crime may well lead to the substitution of even more lethal weapons in the future. Therein lies one of the frailties of Dr Wintemute's product-oriented focus on firearm-related crime. Despite his self-effacing denial that he is not advocating any particular product-based policy agenda, the gist of his article is clear. Because in selected studies medium- to large-caliber semiautomatic pistols appear to be more prevalent in firearm-related homicides, policymakers might do well to consider banning them. What then are policymakers to do when large-caliber revolvers become the criminals' weapon of choice? If the vast majority of homicides occur in circumstances in which long guns could be substituted for
Awards, Appointments, Announcements
Journal: JNCI Journal of the National Cancer Institute (1992)

Awards, Appointments, Announcements Get access JNCI: Journal of the National Cancer Institute, Volume 84, Issue 24, 16 December 1992, Pages 1864–1865, https://doi.org/10.1093/jnci/84.24.1864 Published: 16 December 1992
Inclusion Bodies in Measles Encephalitis
Authors: John M. Adams
Journal: JAMA (1966)

New evidence is presented for the first time to uphold the concept that the measles virus is primarily responsible for the signs, symptoms, and pathological changes in measles encephalitis. The presence of cytoplasmic or nuclear inclusion bodies, or both, in brain tissues of 15 patients from 20 cases supports the direct viral etiology of this disease. Multinucleated giant cells, an additional hallmark of the measles virus, have been found in five patients. This series of 20 fatal cases, the largest in the literature, has been collected from 12 different sources in Mexico and the United States. Greenfield<sup>1</sup>cites the earliest case of measles encephalitis in England as that reported by Lucas<sup>2</sup>in 1790 who wrote "An Account of Uncommon Symptoms Following the Measles." The original pathological descriptions of myelitis following measles were made by Barlow and Penrose in 1886.<sup>3</sup>Not until the 1920's were clear reports of
Stones Are Crushed and Many Patients Elated By Results of New ESWL Therapy
Authors: Marsha F. Goldsmith
Journal: JAMA (1986)

"LIKE A LOUD cap pistol... a staple gun... a rifle shot." Whatever the aural image, these descriptions echo the new sound of success for urologists vanquishing an age-old foe: kidney stones. The blasts—lasting a fraction of a second each but occurring up to 1800 times in the course of one usual treatment—are made by the Dornier Kidney Lithotripter, or "stone crusher," a device developed by the German aerospace corporation (and marketed by Dornier Medical Systems, Inc, Marietta, Ga) for disintegrating renal and upper ureteral calculi by means of acoustic shock waves (<i>JAMA</i>[MEDICAL NEWS] 1983;249:2434-2435). Seldom has a new medical therapy— not to speak of one requiring an outlay of nearly $2 million for equipment— gained so many satisfied adherents so fast. According to a report issued this May by the Congressional Office of Technology Assessment (OTA) (<i>Health Technology Case Study 36: Effects of Federal Policies in Extracorporeal Shock Wave</i>
Intraluminal Hematoma
Authors: DAVID J. MacFARLANE, BARRY SHULKIN
Journal: Clinical Nuclear Medicine (1995)

Radiolabeled leukocytes are used increasingly in febrile seriously ill patients to localize sites of infection. The authors describes the results of one such study of a 57-year-old man who had a massive upper gastrointestinal hemorrhage soon after injection of the labeled cells. Clotted blood within the foregut produced an unusual epigastric accumulation of labeled leukocytes in a configuration atypical for that usually associated with intraluminal bleeding. Of a total of three sites of abnormal tracer accumulation in this patient, only one represented a confirmed focus of infection. The diagnosis of an infective focus on the basis of a radiolabeled leukocyte study should be made with care in patients who have undergone invasive procedures on experienced bleeding episodes.
Aplastic Crisis or Erythroid Hypoplasia in Sickle Cell Disease?
Authors: Terence L. Chorba
Journal: JAMA (1986)

<h3>To the Editor.—</h3> A recent letter by Rosner<sup>1</sup>is critical of the use of the term "aplastic crisis" to describe the transient red cell aplasia occasionally observed in association with human parvovirus B19 infection<sup>2-5</sup>in children with sickle cell disease or other hereditary hemolytic anemias. Rosner contends that the phrase "aplastic crisis" is a misnomer because only "erythroid hypoplasia" occurs in this clinical entity. Whereas erythroid hypoplasia is the principal and most consistent hematologic manifestation in parvovirusinduced aplastic crisis, transient thrombocytopenia<sup>2-4</sup>and leukopenia<sup>3,4</sup>or neutropenia<sup>5</sup>occasionally have also been observed in association with aplastic crisis. Erythroid hypoplasia is also observed in other disease states with transient or chronic bone marrow failure, eg, in aplastic anemia or in transient erythroblastopenia of childhood. The exclusive use of the term "erythroid hypoplasia" in place of "aplastic crisis" to describe the clinical entity of transient parvovirus-induced bone marrow aplasia
Brachial Plexus Block
Authors: Wen-hsien Wu
Journal: JAMA (1971)

A new double-needle technique for brachial plexus block via the axillary route has been used in 30 patients. The results have been evaluated against those of a control group in which the classic method for the block was used. Simplicity in performance, high success rate, and a reduced chance of traumatizing the neurovascular tissue stand out as advantages of the new technique.
Improving Success Rates of Kidney Transplantation
Authors: Paul I. Terasaki
Journal: JAMA (1983)

One-year patient survival rates have improved remarkably, from 84% in 1968 to 97% in 1980 for parental donor grafts, and from 65% to 90% for cadaver donor grafts. In contrast, graft survival rates showed a steady decline from 1968 to 1975 but subsequently improved at a rate of 2.4% per year for parent donor transplants and 2.7% per year for cadaver donor transplants. During this period of improving survival rates, the pretransplant transfusion exposure rate increased from 52% in 1977 to 91% by 1981. We conclude that transplantation has now reached a new level of acceptability as a clinical treatment modality and that blood transfusion has produced its effect on graft survival when results are disseminated over a large number of transplant centers. (<i>JAMA</i>1983;250:1065-1068)
Early Diabetes Mellitus in Perspective
Authors: John B. O'Sullivan
Journal: JAMA (1966)

An epidemiologic study of the town of Sudbury, Mass, has resolved the disparity in reported prevalence rates for early diabetes mellitus. When diagnoses required elevated postprandial blood sugars and an abnormal glucose tolerance test (GTT), 0.8% of the population were found to have previously unrecognized diabetes. A substudy on a random 5% sample of the population indicated that prevalence determined by the GTT alone, without postprandial prescreening, would be 1.2%. Furthermore, the diagnostic criteria of Fajans and Conn, and of the British Diabetes Association give rates of 5.6% and 6.8%, respectively, for the same data. Moreover, diagnoses based on a single postglucose value gave figures ranging from 8.1% to 13.4%. Elevations of both postprandial and postglucose values are considered to indicate active clinical diabetes. Postglucose abnormalities alone, indicative of chemical diabetes, are considered meaningful, however, for their relationship to increased atherosclerotic vascular disease.
Man's Greatest Victory Over Tuberculosis
Journal: JAMA (1941)

The major part of this book is devoted to tuberculosis in cattle. There is recorded step by step in the single chapters the methods that have been used to diagnose, to treat and to prevent tuberculosis in cattle. The program of the veterinarian as emphasized throughout the book has been fully effective in the United States since, in 1917, veterinary science and administration made plans on a large scale to eradicate the disease in animals. The single chapters of the monograph give an excellent review of the history of tuberculosis in animals as well as in human beings. To mention only a few items: cattle as the core of civilization; diseases among animals; recognition, sacrifices and accomplishments of the veterinarians; the United States Bureau of Animal Industry; geographic distribution and prevalence of tuberculosis in cattle. There are some more chapters on the nature of tuberculosis, the tubercle bacillus, tuberculin and
Nomenclature for Mononucleosis Syndromes
Authors: Robert J. Hoagland
Journal: JAMA (1975)

<h3>To the Editor.—</h3> Dr Jordan's "Nomenclature for Mononucleosis Syndromes" (p 45) contains a statement that his use of the term mononucleosis "pertains only to those cases that meet standard clinical and hematologic criteria for infectious mononucleosis." This passage refers to my work in which I have emphasized the need for three criteria—clinical, hematologic, and serologic—for valid diagnoses. However, two paragraphs later, Dr Jordan states that Klemola<sup>1</sup>has shown that the cytomegaloviruses (CMV) can cause a form of mononucleosis that is always heterophil antibody-negative. Yet, the article by Klemola et al<sup>2</sup>concerns a disease that is<i>not</i>clinically similar to mononucleosis (and is, in fact, serologically different as well). Also, in another reference, Klemola et al reported on patients whose serologic<i>and</i>clinical manifestations were not those of infectious mononucleosis. Dr Jordan's statement: "In general, patients with CMV mononucleosis have less striking pharyngitis," is not accurate. An accurate statement