tbuckley/cabot-search huggingface dataset:
New and Nonofficial Remedies
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Principles of Radiography.
Journal: JAMA (1923)

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Federal Income Tax Guide for Physicians
Journal: JAMA (1962)

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SPONTANEOUS GENERATION.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diet in Sinus Infections and Colds.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ASSOCIATION OF AMERICAN MEDICAL COLLEGES.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Story of the Bacteria and Their Relations to Health and Disease.
Journal: JAMA (1889)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Anatomy and Physiology of Capillaries.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
General Internal Medicine
Authors: Eric B. Larson
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cell-Mediated Immunity Directed Against a Syngeneic Plasma Cell Tumor in the Mouse. Detection by Macrophage-Migration Inhibition Test
Journal: JNCI Journal of the National Cancer Institute (1972)

The macrophase-migration inhibition test was used to detect antitumor immunity in a syngeneic system: BALB/c mice immunized against a plasma cell tumor. Migration of peritoneal exudate cells, as well as spleen cells, was assayed. Migration of both cell populations was specifically inhibited in the presence of tumor cells and specifically immunized splenic lymphocytes. This reaction was mediated by a soluble factor that was demonstrated in the supernatant from mixtures of immune lymphocytes and tumor cells. An allogeneic system was tested as a positive control.
Aortocoronary Bypass With Saphenous Vein Graft
Authors: H. Edward Garrett
Journal: JAMA (1973)

A 42-year-old man had extensive occlusive disease of the coronary artery and angina pectoris. An autogenous saphenous vein bypass from the ascending aorta to the anterior descending coronary artery was performed on Nov 23, 1964. The patient suffered an asymptomatic anterior myocardial infarction during operation but made an uncomplicated recovery. Seven years after the operation, the graft functions with normal left ventricular hemodynamics, while the occlusive process has produced obstruction of the left main coronary artery and almost complete occlusion of the right coronary artery. To our knowledge, this is the first successful case of a saphenous veincoronary artery bypass with the longest follow-up of a functioning coronary vein bypass graft.
Recurrent but Short-Lived Duplications of Centromeric Proteins in Holocentric<i>Caenorhabditis</i>Species
Authors: Lews Caro, Pravrutha Raman, Florian A Steiner, Michael Ailion, Harmit S Malik
Journal: Molecular Biology and Evolution (2022)

Abstract Centromeric histones (CenH3s) are essential for chromosome inheritance during cell division in most eukaryotes. CenH3 genes have rapidly evolved and undergone repeated gene duplications and diversification in many plant and animal species. In Caenorhabditis species, two independent duplications of CenH3 (named hcp-3 for HoloCentric chromosome-binding Protein 3) were previously identified in C. elegans and C. remanei. Using phylogenomic analyses in 32 Caenorhabditis species, we find strict retention of the ancestral hcp-3 gene and 10 independent duplications. Most hcp-3L (hcp-3-like) paralogs are only found in 1–2 species, are expressed in both males and females/hermaphrodites, and encode histone fold domains with 69–100% identity to ancestral hcp-3. We identified novel N-terminal protein motifs, including putative kinetochore protein-interacting motifs and a potential separase cleavage site, which are well conserved across Caenorhabditis HCP-3 proteins. Other N-terminal motifs vary in their retention across paralogs or species, revealing potential subfunctionalization or functional loss following duplication. An N-terminal extension in the hcp-3L gene of C. afra revealed an unprecedented protein fusion, where hcp-3L fused to duplicated segments from hcp-4 (nematode CENP-C). By extending our analyses beyond CenH3, we found gene duplications of six inner and outer kinetochore genes in Caenorhabditis, which appear to have been retained independent of hcp-3 duplications. Our findings suggest that centromeric protein duplications occur frequently in Caenorhabditis nematodes, are selectively retained for short evolutionary periods, then degenerate or are lost entirely. We hypothesize that unique challenges associated with holocentricity in Caenorhabditis may lead to this rapid “revolving door” of kinetochore protein paralogs.
Lasker Honors Discovery of Cell Adhesion Molecules
Journal: Cancer Discovery (2022)

Abstract The prestigious Albert Lasker Basic Medical Research Award went to three scientists—Richard Hynes, PhD; Erkki Ruoslahti, MD, PhD; and Timothy Springer, PhD—who discovered how adhesion molecules known as integrins mediate interactions of cells with their neighbors and their surroundings, a process critical to tumor cell migration and invasion.
Isoniazid Hepatitis
Authors: SAMUEL C. STEIN
Journal: Annals of Internal Medicine (1974)

Comments1 March 1974Isoniazid HepatitisSAMUEL C. STEIN, M.D., M.Med.sc., F.A.C.P.SAMUEL C. STEIN, M.D., M.Med.sc., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-80-3-423_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: An excellent paper by Maddrey and Boitnott in your July issue (Ann Intern Med 79:1-12, 1973) has well documented the clincal features of isoniazid hepatitis. Their data and the correlation with hepatitis in the general population are revealing and add further confirmation of the problem.The Chronic Respiratory Disease Section was alerted to the possible correlation of isoniazid ingestion with the occurrence of hepatitis in 1968. After this alert the tuberculosis controller instituted a city-wide surveillance project.The City of Philadelphia has nine districts with health centers that operate chest clinics, Protocols for therapy and prophylaxis were... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: SAMUEL C. STEIN, M.D., M.Med.sc., F.A.C.P.Affiliations: Chronic Respiratory Disease Section Division of Epidemiology, Community Health Services Philadelphia Department of Public Health Philadelphia, Pennsylvania 19146 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHazards and Complications of BCG Immunotherapy 1 March 1974Volume 80, Issue 3Page: 423-424KeywordsHepatitisIngestionIsoniazidProphylaxisPulmonary diseasesThorax ePublished: 1 December 2008 Issue Published: 1 March 1974 PDF downloadLoading ...
Another Indication for Screening and Early Intervention: Problem Drinking
Authors: David C. Parish
Journal: JAMA (1997)

The article in this issue ofTHE JOURNALon the effect of brief physician counseling on problem drinkers' intake of alcohol and use of health services<sup>1</sup>is important to primary care for 2 major reasons. First, evidence that intervention decreases alcohol intake and health problems should be a strong motivator for including alcohol screening in practice. Second, this article contributes to the literature on the powerful impact of physician counseling on behavior. Most physicians care for patients with alcohol problems. During clinical training we have all been exposed to individuals who experience recurring health problems related to alcoholism. A patient's failure to alter the course of his or her addiction, even in the face of impending death, leads to an impression that patients with alcohol problems rarely respond to treatment. This impression is even carried into texts See also p 1039. of medicine. The most recent edition of<i>Cecil</i>
Morphology of Postcapillary Venules Under Different Experimental Conditions&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;
Authors: Krüger, Gerhard
Journal: JNCI Journal of the National Cancer Institute (1968)

Journal Article Morphology of Postcapillary Venules Under Different Experimental Conditions Get access Gerhard Krüger Gerhard Krüger Laboratory of Pathology, National Cancer Institute,4Bethesda, Maryland 20014 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 41, Issue 2, August 1968, Pages 287–301, https://doi.org/10.1093/jnci/41.2.287 Published: 01 August 1968 Article history Received: 01 March 1967 Accepted: 17 April 1968 Published: 01 August 1968
No Expression of a Rous Sarcoma Virus-Induced Tumor Antigen in Mammalian Cells Infected With Retroviruses Transducing Other Oncogenes of the &lt;italic&gt;src&lt;/italic&gt; Gene Family&lt;xref ref-type="fn" rid="FN1"&gt;2&lt;/xref&gt;
Authors: Noboru Kuzumaki, Seiji Yamagiwa, Tsuneyuki Oikawa
Journal: JNCI Journal of the National Cancer Institute (1985)

Immunization with mouse and rat cells transformed by Rous sarcoma virus (RSV) or by B77 avian sarcoma virus (ASV) induced complete transplantation resistance against an RSVinduced mouse tumor (CSA1M) in syngeneic hosts. In contrast, most of the mice immunized with a Fujinami sarcoma virus-transformed rat fibroblast line (FSV-3Y1), a feline sarcoma virustransformed cat fibroblast line (FeSV-FEF), an Abelson leukemia virus-infected Balb/3T3 cell line (AbLV-3T3), or an uninfected 3Y1 cell line could not reject the CSA1M. Serologic analysis with the use of a complement-dependent cytotoxicity assay supported the results of transplantation studies. The mouse and rat cells transformed by RSV or B77 ASV expressed a common tumor-specific cell surface antigen (TSSA) detected by syngeneic antiserum against the CSA1M, whereas none of the FSV-3Y1, FeSV-FEF, and AbLV-3T3 cells expressed the TSSA. These results suggest that the common TSSA in the mouse and rat cells transformed by RSV or B77 ASV containing src gene is not shared with mammalian cells infected with retroviruses transducing other oncogenes of the src gene family (Le., fps, fes, and abl).
Migration of Steinmann Pin From Shoulder to Lung
Authors: James S. McCaughan
Journal: JAMA (1969)

<h3>To the Editor:—</h3> The migration of nails and pins from the femur into the acetabulum and bladder and various other foreign body migrations have been reported. Tristan and Daughtridge<sup>1</sup>reported on the migration of a smooth Steinmann pin into the lung, but we were not able to find any description of the migration of a threaded Steinmann pin from the shoulder into the lung. Here is such a case. <h3>Report of a Case:</h3> A 12-year-old boy sustained a birth injury involving the left brachial plexus and had a flail left shoulder. On Nov 13, 1964, in an arthrodesis of the left shoulder two threaded Steinmann pins were used (Fig 1). This healed without event until Feb 3, 1968, when the patient was admitted to the hospital with a two-day history of hemoptysis and fever. The temperature (oral) was 105 F (40.6 C), and he was coughing up gross blood.
Osteosarcoma Patients: Isolation of Serum Antibodies by Affinity Chromatography<xref ref-type="fn" rid="fn2">2</xref><xref ref-type="fn" rid="fn3">3</xref>
Authors: Kwong-Y. Tsang, H. Hugh Fudenberg, Mark J. Gnagy
Journal: JNCI Journal of the National Cancer Institute (1981)

Antibodies specific for membrane-associated antigens of human osteosarcoma cells were isolated from sera of 12 patients with osteosarcoma (OS). Affinity columns were prepared by coupling partially purified membrane antigens from cultured human as cell lines (TE-85 or LM) to CBrN-activated Sepharose 4B. The antigens were prepared by discontinuous sucrose gradient ultracentrifugation, papain digestion, and DEAE column chromatography. Diluted serum was passed over the affinity columns, and the adsorbed proteins were eluted with 2.5 M MgCI2 (pH 6.5). Immunodiffusion, indirect immunofluorescence, and complement fixation were used to assay antibody activity in the eluate. Specific anti-OS activity was found in the immunoglobulin (Ig) fraction isolated from the sera of the 12 as patients, as confirmed by blocking experiments. No anti-OS antibody activity was found in sera from healthy individuals or patients with breast carcinoma, clear cell carcinoma, liposarcoma, or leukemia in this study. The anti-OS activity of the isolated Ig from as patients was abolished after absorption with cultured human as cells from lines LM, TE-85, or G292 but not after absorption with cells from lines WI-38 (embryonic lung), TE-32 (rhabdomyosarcoma), CAMA-1 or SW527 (breast carcinoma), or M-14 (melanoma). Absorption with rabbit antihuman IgG but not with rabbit antihuman IgM immunobeads completely eliminated the antibody activity.