tbuckley/cabot-search huggingface dataset:
Fragile X chromosome related to mental retardation in males
Journal: JAMA (1979)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Die Prokto-Sigmoskopie und ihre Bedeutung für die Diagnostik und Therapie der Krankheiten des Rektum und des Sigmoideum.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
8. Pharmacologic Approaches to Glycemic Treatment: <i>Standards of Medical Care in Diabetes—2018</i>
Journal: Diabetes Care (2017)

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations, please refer to the Standards of Care Introduction. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.
Explaining Variations in Hospital Death Rates
Authors: Nancy E. Gary
Journal: JAMA (1991)

<h3>To the Editor.—</h3> I read with interest the article by Park et al.<sup>1</sup>Using 6-year-old data, the authors from the RAND Corporation showed that death rates for 1126 patients with congestive heart failure and 1150 patients with acute myocardial infarction in targeted hospitals were 5 to 10.9 higher per 100 admissions than in all other hospitals studied. The report suggests that 56% to 82% of the excess deaths could result from "purely random variation." After review of patients' medical records, the authors concluded that a statistically significant difference in mortality could not be explained by the quality of the process of care. The Health Care Financing Administration (HCFA), through appropriate state agencies, inspects institutions that have shown for 2 years higher than expected death rates. The purpose of these on-site surveys is to determine compliance with Medicare's conditions of participation, and measures of quality such as infection control processes,
A Phase Ib/II Study of Ibrutinib in Combination with Obinutuzumab-Gazyva As First-Line Treatment for Patients with Chronic Lymphocytic Leukemia &gt; 65 Years Old or with Coexisting Conditions
Authors: Juliana Velez Lujan, Michael Y. Choi, Chaja Jacobs, Colin McCarthy, Alaina Heinen, Carlos Amaya-Chanaga, Thomas J. Kipps, Januario E Castro
Journal: Blood (2018)
Inappropriate drug prescribing for the community-dwelling elderly
Authors: S. M. Willcox
Journal: JAMA (1994)

<h3>Objective.</h3> —To examine the amount of inappropriate drug prescribing for Americans aged 65 years or older living in the community. <h3>Design.</h3> —Cross-sectional survey of a national probability sample of older adults. <h3>Setting.</h3> —The 1987 National Medical Expenditure Survey, a national probability sample of the US civilian noninstitutionalized population, with oversampling of some population groups, including the elderly. <h3>Subjects.</h3> —The 6171 people aged 65 years or older in the National Medical Expenditure Survey sample, using appropriate weighting procedures to produce national estimates. <h3>Main Outcome Measures.</h3> —Incidence of prescribing 20 potentially inappropriate drugs, using explicit criteria previously developed by 13 United States and Canadian geriatrics experts through a modified Delphi consensus technique. Three cardiovascular drugs identified as potentially inappropriate were analyzed separately since they may be considered appropriate for some noninstitutionalized elderly patients. <h3>Results.</h3> —A total of 23.5% (95% confidence interval [CI], 22.4% to 24.6%) of people aged 65 years or older living in the community, or 6.64 million Americans (95% CI, 6.28 million to 7.00 million), received at least one of the 20 contraindicated drugs. While 79.6% (95% CI, 77.2% to 82.0%) of people receiving potentially inappropriate medications received only one such drug, 20.4% received two or more. The most commonly prescribed of these drugs were dipyridamole, propoxyphene, amitriptyline, chlorpropamide, diazepam, indomethacin, and chlordiazepoxide, each used by at least half a million people aged 65 years or older. Including the three controversial cardiovascular agents (propranolol, methyldopa, and reserpine) in the list of contraindicated drugs increased the incidence of probably inappropriate medication use to 32% (95% CI, 30.7% to 33.3%), or 9.04 million people (95% CI, 8.64 million to 9.44 million). <h3>Conclusion.</h3> —Physicians prescribe potentially inappropriate medications for nearly a quarter of all older people living in the community, placing them at risk of drug adverse effects such as cognitive impairment and sedation. Although most previous strategies for improving drug prescribing for the elderly have focused on nursing homes, broader educational and regulatory initiatives are needed. (<i>JAMA</i>. 1994;272:292-296)
Special Study Traces Facial Growth Of Patients With Cleft Palates, Lips
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Announcement:Fungal Disease Awareness Week — August 14–18, 2017
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

In 2017, CDC initiated a national observance, Fungal Disease Awareness Week, to increase awareness about fungal diseases, which can cause severe illness but frequently go undiagnosed. Awareness is one of the most important means to reduce delays in diagnosis and treatment, which can lead to better health outcomes and save lives.
Improving Improvement
Authors: Bruce D. Agins, Clemens Steinbock
Journal: Annals of Internal Medicine (2004)

Letters16 November 2004Improving ImprovementBruce D. Agins, MD, MPH and Clemens Steinbock, MBABruce D. Agins, MD, MPHFrom AIDS Institute, New York State Department of Health, New York, NY 10001.Search for more papers by this author and Clemens Steinbock, MBAFrom AIDS Institute, New York State Department of Health, New York, NY 10001.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-141-10-200411160-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The landmark study by Landon and colleagues (1) is a rigorous evaluation of a major HIV quality improvement (QI) initiative and of large-scale QI collaboratives. Specific factors pertinent to the national network of HIV services in the United States temper the findings of this important study, particularly with respect to comparison of results between intervention and control clinics.Although the authors carefully mentioned that their results may have been contaminated because control clinics participated in another QI program, they suggested that this intervention occurred before the collaborative. In fact, it continued during the collaborative and is ongoing. ...Reference1. Landon BE, Wilson IB, McInnes K, Landrum MB, Hirschhorn L, Marsden PV, et al. Effects of a quality improvement collaborative on the outcome of care of patients with HIV infection: the EQHIV study. Ann Intern Med. 2004;140:887-96. [PMID: 15172903] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From AIDS Institute, New York State Department of Health, New York, NY 10001. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffects of a Quality Improvement Collaborative on the Outcome of Care of Patients with HIV Infection: The EQHIV Study Bruce E. Landon , Ira B. Wilson , Keith McInnes , Mary Beth Landrum , Lisa Hirschhorn , Peter V. Marsden , David Gustafson , and Paul D. Cleary Improving Improvement Bruce E. Landon , Paul D. Cleary , and Ira B. Wilson Improving Improvement Paul Batalden Metrics Cited byElectronic health information technology as a tool for improving quality of care and health outcomes for HIV/AIDS patients 16 November 2004Volume 141, Issue 10Page: 821KeywordsAIDSHIVHealth services administration and managementPatientsQuality improvement ePublished: 16 November 2004 Issue Published: 16 November 2004 Copyright & PermissionsCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Advisory Board and Contents
Authors: Fumihiro Kano, Josep Call, Christopher Krupenye, Daniel Horschler, Evan Maclean, Laurie Santos, Mariam Aly, Friedemann Pulvermüller, Luigi Grisoni, Catharina Zich, Andrew Quinn, Lydia Mardell, Nick Ward, Sven Bestmann, Jonathan Birch, Alexandra Schnell, Nicola Clayton, Patricia Lockwood, Matthew Apps, Steve Chang, Jaan Aru, Mototaka Suzuki, Matthew Larkum, Lindsey Drayton, Jessica Miles, Rolf Van Der Sanden, Patrick Scheffmann, Ralph Adolphs, Renee Baillargeon, Nick Chater, Peter Dayan, Stanislas Dehaene, Daniel Dennett, Yadin Dudai, Andreas Engel, Martha Farah, Angela Friederici, Okihide Hikosaka, Ray Jackendoff, Philip Johnson-Laird, Nancy Kanwisher, Christof Koch, Marta Kutas, Nikos Logothetis, James Mcclelland, Earl Miller, Elizabeth Phelps, Russell Poldrack, Marcus Raichle, Trevor Robbins, Anthony Wagner, Vincent Walsh
Journal: Trends in Cognitive Sciences (2020)
Migration of the elderly from high altitudes in Colorado
Authors: J. G. Regensteiner
Journal: JAMA (1985)

The reason for the reported decline in the proportion of elderly (&gt;60 years) persons at high (&gt;2,456 m) compared with low altitude (&lt;1,376 m) in Colorado was unknown. We hypothesized that adverse effects of high altitude on the elderly, particularly those with heart and lung diseases, prompted their migration to lower elevations. Colorado census data indicated that selective out-migration occurred from high to low altitude among the elderly. Interviews (n=833) in high- and low-altitude Colorado towns revealed that the elderly were unique in that they moved down for reasons of poor health and that for the majority (81%) ill health meant heart and lung diseases. Elderly migrants from high altitude reported heart and lung diseases more frequently than those remaining and cited improvement in symptoms at low altitude. We suggest that symptoms of heart and lung disease are exacerbated with advancing age at high altitude and influence choice of residence. (<i>JAMA</i>1985;253:3124-3128)
Heberden Society
Journal: Annals of the Rheumatic Diseases (1959)

KELLGREN (Manchester) presented an exhibition illus- trating a review of 29 patients considered in 1950 to have generalized osteo-arthritis.This series will form the subject of a paper to be published in a future issue of the Annals.MR.J. H. CREGAN (Buxton) presented a patient with rheumatoid arthritis complicated by cervical subluxation and paraplegia.DR.R. HARRIS (Buxton) exhibited studies on the circulation of joints, using 23Na Sodium chloride.MR.J. CHARNLEY (Manchester) demonstrated fluon ("Teflon") prostheses for use in arthroplasty of the hip.Papers.-The following papers were read by mem- bers of the
Trapped fingers
Authors: C A Hajivassiliou
Journal: BMJ (1994)

competence.Their responsibility indicates that it is not professional medical bodies that lack commitment in requiring doctors to acquire detailed knowledge of mental health law.The Royal College of Psychiatrists is currently exploring, with colleagues at the Department of Health, ways of providing such training in mental health law both for trainees and as part of continuing professional development for estab- lished consultant psychiatrists and general practitioners.
Safer motoring.
Authors: A Singh
Journal: BMJ (1973)

19Sthat some will always leach out into fluids stored or run through such plastics.What is needed is an ester of low innate toxicity such as DEHP but one for which hydrolytic esters are fairly widespread in nature.Then amounts injected into patients will not accumulate and the larger quantities from industrial waste will be rapidly degraded when they enter sewage systems.
Authors’ correction for Euro Surveill. 2018;23(5)
Journal: Eurosurveillance (2018)

© This work is licensed under a Creative Commons Attribution 4.0 International License. Closure This is a corrected article applying to the following content: Early season co-circulation of influenza A(H3N2) and B(Yamagata): interim estimates of 2017/18 vaccine effectiveness, Canada, January 2018
Correction
Journal: Circulation Research (2013)

the authors recently discovered that one mutant sample in the study was mistakenly identified.In specific, the mutant sample (TPM1 mut ) that encodes a mutation in the gene of tropomyosin (TPM1) has been previously identified as M281T (a methionine was mutated to threonine at residue 281).However, liquid chromatography-mass spectrometry with peptide mass fingerprinting (LC-MS/MS) data has revealed that the mutation in the TPM1 mut sample is consistent with I284V (isoleucine residue is mutated into a valine).This means that the mutation occurred on residue 284 (the last amino acid residue of tropomyosin), and not residue 281.The specific alteration of the TPM1 mut sample identification to I284V will not change, in any form, the message of the paper, and importantly will not affect the discussion and findings that concern the TPM1 mut sample.
Long-term integrity of renal function in cadaver allografts
Authors: W. D. Shelp
Journal: JAMA (1970)

In general, renal transplant recipients of cadaver kidneys fare less well than recipients of living related donor kidneys in regard to incidence of rejection episodes and stability of renal function. Specific renal function measurements of four cadaver recipients surviving a mean of 29 months without experiencing rejection are compared with those of seven well-matched living related donor recipients who have maintained optimal stability of renal function a minimum of one year following transplant. Renal function of the cadaver group compared favorably and in certain instances exceeded that of the living donor group. These data indicate that even without histocompatibility testing, transplantation of cadaver kidneys can occasionally result in a sustained preservation of renal function which closely parallels that seen in well-matched recipients. Excluding chance histocompatibility, the factors related to such therapeutic success are unknown.
Intravenous drug abuse and one academic health center
Authors: P. E. Dans
Journal: JAMA (1990)

Increasing reports of management problems involving intravenous drug abuse patients prompted our study. From 1983 to 1988, the recorded inpatient prevalence of diagnoses consistent with drug abuse/dependence, other than alcohol or nicotine, rose hospitalwide from 0.6% to 3.5%. Disruptive behavior was documented in the records of 38 of 71 active cocaine or heroin users admitted during 1988 vs 12 of 64 matched control subjects. Care and teaching focused principally on secondary complications of intravenous drug use. Study recommendations included (1) establishment of a comprehensive substance abuse treatment, education, and research program with a dedicated inpatient unit; (2) use of an explicit social contract between patients and care givers; and (3) staff education about legal limits in managing disruptive patients and searching for illegal substances. Primary and secondary prevention, including combating societal enabling of substance abuse, should be the institution's long-term goals. (<i>JAMA</i>. 1990;263:3173-3176)
Consumption a Curable and Preventable Disease. What a Layman Should Know About It.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Endothelial aging
Authors: R BRANDES, I FLEMING, R BUSSE
Journal: Cardiovascular Research (2005)

Aging is considered to be the major risk factor for the development of atherosclerosis and, therefore, for coronary artery disease. Apart from age-associated remodeling of the vascular wall, which includes luminal enlargement, intimal and medial thickening, and increased vascular stiffness, endothelial function declines with age. This is most obvious from the attenuation of endothelium-dependent dilator responses, which is a consequence of the alteration in the expression and/or activity of the endothelial NO synthase, upregulation of the inducible NO synthase, and increased formation of reactive oxygen species. Aging is also associated with a reduction in the regenerative capacity of the endothelium and endothelial senescence, which is characterized by an increased rate of endothelial cell apoptosis.
Infectious and serum viral hepatitis: differentiation with serum IgM and thymol turbidity as criteria
Authors: V. T. Barreto
Journal: JAMA (1972)

Serum levels of IgM and thymol turbidity were determined in 31 patients with Australia antigen-negative, documented short-incubation infections with the infectious hepatitis (IH) virus, and 65 patients with Australia antigen-positive, long-incubation serum hepatitis (SH) infections. During the acute phase, IgM and thymol turbidity levels were significantly higher in patients with IH than in those with SH infections. However, the overlap was so great that neither test clearly distinguished between the two groups. Following recovery in both groups, IgM level usually returned to normal, but the thymol turbidity level often remained elevated. Of patients with prolonged active SH hepatitis, only half had raised levels of IgM and thymol turbidity. We conclude that neither the IgM level nor the thymol turbidity level clearly distinguishes between IH and SH infections or provides a reliable index of disease activity.