tbuckley/cabot-search huggingface dataset:
Ascitic fluid mid-regional-pro-adrenomedullin (MR-pro-ADM): a novel rapid-assay sepsis biomarker to diagnose spontaneous bacterial peritonitis in cirrhotic patients
Authors: Abderrahim Oussalah, Anne-Sophie Lagneaux, Tom Alix, Pierre Filhine-Tresarrieu, Jonas Callet, Janina Ferrand, Jean Jung, Julien Broseus, Sylvain Salignac, Amandine Luc, Cédric Baumann, Philipp Schuetz, Alain Lozniewski, Katell Peoch, Hervé Puy, Jean-Louis Guéant, Jean-Pierre Bronowicki
Journal: Journal of Hepatology (2022)
MiR-122, the regulator of the immune privileged liver
Authors: Maytal Gefen, Shanny Layani, Emma Klahr, Mor Hindi, Nofar Rosenberg, Rinat Abramovitch, Nathalie Nachmansson, Adi Yehezkel, Amnon Peled, Jacob Rachmilewitz, Michal Abraham, Michael Berger, Daniel Goldenberg, Nicola Gagliani, Samuel Huber, Irm Hermans-Borgmeyer, Rebecca Haffner-Krausz, Shifra Ben-Dor, Yuval Nevo, Shrona Elgavish, Hadar Benyamini, Mathias Heikenwälder, Stefan Rose-John, Dirk Schmist-Arras, Achim Krüger, Michael Stürzl, Elisabeth Naschberger, Frank Tacke, Hilla Giladi, Eithan Galun
Journal: Journal of Hepatology (2022)
In-depth shotgun metagenomic analysis of the oral and gut microbiome identifies striking overlap in microbial community structure, virulence factors and antimicrobial resistance genes based on stage and severity of cirrhosis
Authors: Sunjae Lee, Bethlehem Arefaine, Neelu Begum, Elizabeth Witherden, Marilena Stamouli, Azadeh Harzandi, Ane Zamalloa, Eleanor Corcoran, Roger Williams, Shilpa Chokshi, Gordon Proctor, Adil Mardinoglu, Mathias Uhlen, Saeed Shoaie, Vishal C. Patel
Journal: Journal of Hepatology (2022)
Liver fibrosis burden determines risk of hepatocellular carcinoma among patients with hepatitis B surface antigen seroclearance
Authors: Lung Yi Loey Mak, Ka-Shing Cheung, Rex Wan-Hin Hui, Danny Ka-Ho Wong, Yan Yue James Fung, Man-Fung Yuen, Wai-Kay Seto
Journal: Journal of Hepatology (2022)
Polymorphic analysis of bulevirtide sequence in PreS1 of large HBsAg across HBV genotypes A-H
Authors: Roberto Mateo, Thomas Aeschbacher, Yang Liu, Simin Xu, Bin Han, Tahmineh Yazdi, Savrina Manhas, Lindsey May, Dong Han, Silvia Chang, Rishi Aryal, Ross Martin, Evguenia S Svarovskaia, Hongmei Mo
Journal: Journal of Hepatology (2022)
Orthotopic transplantation of the functional bioengineered liver prolonged survival in rats with total hepatectomy
Authors: Beibei Guo, Li Jiang, Jing Jiang, Qian Zhou, Jiaxian Chen, Jiaojiao Xin, Dongyan Shi, Keke Ren, Xingping Zhou, Genren Yang, Jun Li
Journal: Journal of Hepatology (2022)
ACG–CAG provided suggestions for periendoscopic management of anticoagulants and antiplatelets
Authors: David R. Lichtenstein, Neal D. Dharmadhikari
Journal: Annals of Internal Medicine (2022)

Source Citation Abraham NS, Barkun AN, Sauer BG, et al. American College of Gastroenterology–Canadian Association of Gastroenterology clinical practice guideline: management of anticoagulants and antiplatelets during acute gastrointestinal bleeding and the periendoscopic period. Am J Gastroenterol. 2022;117:542-58. 35297395
Substantial reduction of the diagnostic grey zone of the Baveno-VII CSPH criteria by sequential consideration of VITRO
Authors: Lukas Hartl, Mathias Jachs, Benedikt Simbrunner, David JM Bauer, Rafael Paternostro, Bernhard Scheiner, Lorenz Balcar, Georg Semmler, Albert Stättermayer, Matthias Pinter, Peter Quehenberger, Michael Trauner, Thomas Reiberger, Mattias Mandorfer
Journal: Journal of Hepatology (2022)
Are patients with Fontan-associated liver disease (FALD) appropriately screened for oesophageal varices? Queensland quaternary adult congenital heart disease referral centre experience
Authors: Anthony Bergin, Yuming Ding, Michael Christmas, Wei Lian Tan, Lei Lin, Myat Khaing, Alexandra Schlimmer, Ann Vandeleur, Hayley Thompson, Ryan Maxwell, Vishva Wijesekera, Tony Rahman
Journal: Journal of Hepatology (2022)
Most patients with advanced cirrhosis treated with bulevirtide monotherapy have a non-monophasic HDV RNA decline patterns: an interim kinetic analysis of real-life setting
Authors: Louis Shekhtman, Harel Dahari, Scott Cotler, Elisabetta Degasperi, Maria Paola Anolli, Sara Colonia Uceda Renteria, Dana Sambarino, Marta Borghi, Riccardo Perbellini, Floriana Facchetti, Ferruccio Ceriotti, Pietro Lampertico
Journal: Journal of Hepatology (2022)
Radiomics-based model for outcome prediction in primary sclerosing cholangitis
Authors: Laura Cristoferi, Marco Porta, Davide Bernasconi, Leonardi Filippo, Giacomo Mulinacci, Andrea Palermo, Alessio Gerussi, Miki Scaravaglio, Camilla Gallo, Eliana Stucchi, Cesare Maino, Davide Ippolito, Daphne D’Amato, Carlos Ferreira, Marija Mavar-Haramija, Rajarshi Banerjee, Laura Antolini, Maria Grazie Valsecchi, Stefano Fagiuoli, Pietro Invernizzi, Marco Carbone
Journal: Journal of Hepatology (2022)
Increased hospital admissions for alcohol-associated hepatitis during the COVID-19 pandemic in Alberta, Canada: a retrospective cohort study
Authors: Alexandra Frolkis, Meredith Borman, Matthew Sadler, Stephen Congly, Henry Nguyen, Samuel Lee, Mark G Swain, Kelly Burak, Carla Coffin, Alexander Aspinall, Laura Stanton, Abdel Aziz Shaheen
Journal: Journal of Hepatology (2022)
CRISPR perturbation in iPSC-derived hepatic stellate cells reveals role for TNF-driven interferon response in chronic liver disease
Authors: Kelly Haston, Navpreet Ranu, Lorn Kategaya, Eric Lubeck, Michael D. Bereket, Francesco Paolo Casale, Panagiotis Stanitsas, Alicia Lee, Owen Chen, Bobby Leitmann, Srinivasan Sivanandan, Ahmed Sandakli, Pooja Prasad, Rohit Loomba, Arun Sanyal, Stephen Harrison, Zobair Younossi, Catherine Jia, Grant Budas, James Trevaskis, Robert Myers, David Breckinridge, Ajamete Kaykas, Daphne Koller, Matthew Albert
Journal: Journal of Hepatology (2022)
A bioengineered approach to re-create and study the extracellular matrix-immune cell crosstalk in normal and fibrotic liver
Authors: Sara Campinoti, Claire McQuitty, Lorenzo Caciolli, Bruna Almeida, Lai Wei, Luca Zanieri, Antonio Riva, Alessandro F. Pellegata, Paola Bonfanti, Sara Mantero, Shilpa Chokshi, Luca Urbani
Journal: Journal of Hepatology (2022)
The protective role of dairy protein on sarcopenic obesity in middle-aged and older women: a community-based, 12-year, prospective cohort study
Authors: Jun-Hyuk Lee, Joo Hyun Oh, Sang Bong Ahn, Huiyul Park, Joo Hyun Sohn, Bo-Kyeong Kang, Mi Mi Kim, Chul-min Lee, Dae Won Jun, Eileen Yoon, Hyo Young Lee, Hyunwoo Oh
Journal: Journal of Hepatology (2022)
Safe use of hepatitis B surface antigen positive (HBsAg (+)) grafts in liver transplantation (LT): a nationwide study based on KOTRY (Korean Organ Transplantation Registry) data
Authors: Sujin Gang, YoungRok Choi, Kwang-Woong Lee, Bong Wan Kim, Dong-Sik Kim, Yang Won Nah, Jong Man Kim, Jae Geun Lee, Je Ho Ryu, Jaehong Jeong, Geun Hong, Shin Hwang
Journal: Journal of Hepatology (2022)
Development and validation of a machine learning-based model for varices screening in compensated cirrhosis (CHESS2001): an international multicenter study
Authors: Yifei Huang, Jia Li, Tian-lei Zheng, Dong Ji, Yu Jun Wong, Hong You, Ye Gu, Musong Li, Lili Zhao, Shuang Li, Shi Geng, Na Yang, Guofeng Chen, Yan Wang, Manoj Kumar, Ankur Jindal, Qin Wei, Zhenhuai Chen, Yongning Xin, Zicheng Jiang, Xiaoling Chi, Jilin Chen, Mingxin Zhang, Huan Liu, Ming Lu, Li Li, Yong Zhang, Chunwen Pu, Deqiang Ma, Qibin He, Shanghong Tang, ChunYan Wang, Shiv Kumar Sarin, Xiaolong Qi
Journal: Journal of Hepatology (2022)
Estimations of the global prevalence and clinical burden of occult hepatitis B infection (OBI): a systematic review and meta-analysis
Authors: Yu Ri Im, Rukmini Jagdish, Damien Leith, Jin Un Kim, Gibril Ndow, Kyoko Yoshida, Amir Majid, Yueqi Ge, Yusuke Shimakawa, Maud Lemoine
Journal: Journal of Hepatology (2022)
Secondary infections in hospitalizes patients with cirrhosis: epidemiology, clinical chracteristics and prognostic relevance
Authors: Gustavo Pereira, Caroline Baldin, Juliana Piedade, Nathalia Galhardi, Barbara Rodrigues, Raquel Godoy, Camila Marques de Alcanatara Barreto, Flavia Fernandes
Journal: Journal of Hepatology (2022)
Collateral benefit of Georgia national hepatitis C elimination program-improving blood transfusion safety in the country of Georgia
Authors: Maia Alkhazashvili, Evan Bloch, Shaun Shadaker, Tinatin Kuchuloria, Tamar Samadashvili, Vladimer Getia, Alexander Turdziladze, Jan Drobeniuc, Paige A Armstrong, Amiran Gamkrelidze
Journal: Journal of Hepatology (2022)
Sugar sweetened beverage consumption and liver cancer risk
Authors: Xuehong Zhang, Longgang Zhao, Mace Coday, David O. Garcia, Xinyi Li, JoAnn Manson, Katherine McGlynn, Yasmin Mossavar-Rahmani, Michelle Naughton, Melissa Lopez-Pentecost, Nazmus Saquib, Howard Sesso, Aladdin Shadyab, Michael Simon, Linda Snetselaar, Fred Tabung, Lesley Tinker, Deirdre Tobias, Trang VoPham
Journal: Journal of Hepatology (2022)
Type 2 diabetes combined with portal vein tumor thrombosis worsens prognosis in patients with hepatocellular carcinoma
Authors: Debora Angrisani, Marco Guarracino, Nunzia Farella, Filomena Morisco, Carmine Coppola, Francesco Izzo, Angelo Salomone Megna, Alessandro Federico, Vincenzo Messina, Gerardo Nardone, Guido Piai, Enrico Ragone, Luigi Elio Adinolfi, Giuseppe D’Adamo, Maria Stanzione, Giampiero Francica, Marcello Persico, Vincenzo De Girolamo, Coppola Nicola, Lucia Rocco, Giovan Giuseppe Di Costanzo, Raffaella Tortora
Journal: Journal of Hepatology (2022)
Hepatic expression of secreted calcium-binding protein 2 by hepatic stellate cells is associated with human non-alcoholic fatty liver disease progression
Authors: Frederik Larsen, Mike Terkelsen, Sofie Bendixen, Daniel Hansen, Charlotte Wernberg, Mette Lauridsen, Tina Di Caterino, Fabio Avolio, Majken Siersbæk, Vineesh Indira Chandran, Jonas Graversen, Aleksander Krag, Lars Groentved, Kim Ravnskjaer
Journal: Journal of Hepatology (2022)
Serological assessment of the collagen type III deposition predicts outcome in decompensated liver cirrhosis
Authors: Mette Juul Nielsen, Robert Schierwagen, Christian Jansen, Frank Uschner, Sabine Klein, Maximilian J Brol, Michael Praktiknjo, Chang Johannes, Morten Karsdal, Diana Leeming, Jonel Trebicka
Journal: Journal of Hepatology (2022)
A non-calorie restricted low carbohydrate high fat diet improves non-alcoholic fatty liver disease (NAFLD) activity score (NAS) and HbA1c in type 2 diabetes: a six-month randomised controlled trial
Authors: Camilla Dalby Hansen, Eva-Marie Gram-Kampmann, Johanne Kragh Hansen, Mie Balle Hugger, Bjørn Stæhr Madsen, Jane Jensen, Sara Olesen, Nikolaj Torp, Ditlev Nytoft Rasmussen, Maria Kjærgaard, Stine Johansen, Katrine Prier Lindvig, Peter Andersen, Katrine Thorhauge, Jan Christian Brønd, Pernille Hermann, Henning Beck-Nielsen, Sönke Detlefsen, Torben Hansen, Kurt Højlund, Maja Thiele, Mads Israelsen, Aleksander Krag
Journal: Journal of Hepatology (2022)
CD161 expressing CD4+ CD25hi T cells accumulate in the liver of obese patients with NASH
Authors: Rafael Kaeser, Emilia Schlaak, Franziska Engels, Saskia Killmer, Katharina Zoldan, Lukas Sturm, Lena Mayer, Gabriel Seifert, Jodok Matthias Fink, Goran Marjanovic, Thomas Longerich, Agnieszka Kabat, Edward Pearce, Dominik Bettinger, Maike Hofmann, Robert Thimme, Bertram Bengsch, Tobias Böttler
Journal: Journal of Hepatology (2022)
The efficacy of molecular targeted therapies after atezolizumab plus bevacizumab in patients with unresectable hepatocellular carcinoma (HCC) in Japan
Authors: Kaoru Tsuchiya, Yuka Hayakawa, Yutaka Yasui, Tatsuya Kakegawa, Mayu Higuchi, Kenta Takaura, Shohei Tanaka, Chiaki Maeyashiki, Shun Kaneko, Nobuharu Tamaki, Hiroyuki Nakanishi, Masayuki Kurosaki, Namiki Izumi
Journal: Journal of Hepatology (2022)
Effects of the siRNA JNJ-3989 and/or the capsid assembly modulator (CAM-N) JNJ-6379 on viral markers of chronic hepatitis B (CHB): results from the REEF-1 study
Authors: Man-Fung Yuen, Tarik Asselah, Ira M Jacobson, Maurizia Brunetto, Harry Janssen, Tetsuo Takehara, Jinlin Hou, Thomas Kakuda, Tom Lambrecht, Ronald Kalmeijer, Carine Guinard-Azadian, Cristiana Mayer, John Jerzorwski, Thierry Verbinnen, Oliver Lenz, Umesh Shukla, Michael Biermer
Journal: Journal of Hepatology (2022)
Mechanistic pharmacokinetics/pharmacodynamics modelling of the simultaneous effects of bepirovirsen on hepatitis B surface antigen and alanine transaminase changes in chronic hepatitis B patients: phase 2b analysis to inform phase 3 decision-making
Authors: Amir Youssef, Mohamed Ismail, Mindy Magee, Dickens Theodore, Melanie Paff, Robert Elston, Ahmed Nader
Journal: Journal of Hepatology (2022)
Minos: variant adjudication and joint genotyping of cohorts of bacterial genomes
Authors: Martin Hunt, Brice Letcher, Kerri M. Malone, Giang Nguyen, Michael B. Hall, Rachel M. Colquhoun, Leandro Lima, Michael C. Schatz, Srividya Ramakrishnan, Zamin Iqbal
Journal: Genome biology (2022)

There are many short-read variant-calling tools, with different strengths and weaknesses. We present a tool, Minos, which combines outputs from arbitrary variant callers, increasing recall without loss of precision. We benchmark on 62 samples from three bacterial species and an outbreak of 385 Mycobacterium tuberculosis samples. Minos also enables joint genotyping; we demonstrate on a large (N=13k) M. tuberculosis cohort, building a map of non-synonymous SNPs and indels in a region where all such variants are assumed to cause rifampicin resistance. We quantify the correlation with phenotypic resistance and then replicate in a second cohort (N=10k).
Cyclophilin inhibitor CRV431 as a potential therapy for alcohol-related liver disease
Authors: Elena Palma, Sara Campinoti, Una Rastovic, Nicola Harris, Tsin Shue Koay, Lola Ajayi, Bruna Almeida, Sandra Phillips, Daren Ure, Melissa Preziosi, Marjorie Yumol, Rosa Miquel, Yoh Zen, Andreas Prachalias, Krishna Menon, Nigel Heaton, Luca Urbani, Shilpa Chokshi
Journal: Journal of Hepatology (2022)
In vitro rescue of the bile acid transport function of some ABCB11 variants by CFTR potentiators: a targeted pharmacotherapy in progressive familial intrahepatic cholestasis type 2
Authors: Elodie Mareux, Martine Lapalus, Marion Almes, Pauline Adnot, Mounia Lakli, Amel Ben Saad, Jean-Luc Decout, Thomas Falguières, Isabelle Callebaut, Emmanuel Gonzalès, Emmanuel Jacquemin
Journal: Journal of Hepatology (2022)
Heavy alcohol intake along with ALDH2 polymorphism increases the risk of hepatocellular carcinoma and mortality in hepatitis B virus-related cirrhosis
Authors: Chih-Wen Lin, Ming Chao Tsai, Sien-Sing Yang, Chih-Che Lin, Wen-Lung Wang, Yao-Chun Hsu, Yaw-Sen Chen, Ming-Lung Yu, Jui-Ting Hu
Journal: Journal of Hepatology (2022)
Comparative risk of hepatocellular carcinoma in patients with chronic hepatitis B receiving tenofovir- or entecavir-based regimens: a meta-analysis using individual patient data
Authors: Won-Mook Choi, Terry Cheuk-Fung Yip, Grace Wong, W.Ra Kim, Leland Yee, Craig Brooks-Rooney, Tristan Curteis, Harriet Cant, Chien-Hung Chen, Chi-Yi Chen, Yi-Hsiang Huang, Young-Joo Jin, Dae Won Jun, Jin-Wook Kim, Neung Hwa Park, Cheng-Yuan Peng, Hyun Phil Shin, Jungwoo Shin, Yao-Hsu Yang, Young-Suk Lim
Journal: Journal of Hepatology (2022)
Cost- effectiveness evaluation of the hepatitis C elimination strategy in Cyprus in the era of affordable direct-acting antivirals
Authors: Ilias Gountas, Petros Katsioloudes, Ioanna Yiasemi, Evi Kyprianou, Christos Mina, Chrysanthos Georgiou, Antri Kouroufexi, Anna Demetriou, Eleni Xenofontos, Georgios Nikolopoulos
Journal: Journal of Hepatology (2022)
Portal pressure decreasing effect of beta blockers in cirrhosis with clinically significant portal hypertension, according to the components of metabolic syndrome
Authors: Anna Brujats, Berta Cuyas, Edilmar Alvarado-Tapias, Claudia Pujol, Antoni Mombiela, Cristina Roig, Maria Poca, Xavier Torras, Àngels Escorsell, Càndid Villanueva
Journal: Journal of Hepatology (2022)
Risk prediction of hepatocellular carcinoma in chronic hepatitis B patients outside current treatment criteria
Authors: Gi-Ae Kim, Seungbong Han, Young-Suk Lim, Gwang Hyeon Choi, Jonggi Choi, Dong Hyun Sinn, Yong Han Paik, Jeong-Hoon Lee, Ju-Yeon Cho
Journal: Journal of Hepatology (2022)
Safety, pharmacokinetics, and antiviral activity of the S-antigen Transport Inhibiting Oligonucleotide Polymers (STOPS) drug candidate ALG-010133 in subjects with chronic hepatitis B
Authors: Edward J Gane, Kosh Agarwal, Man-Fung Yuen, Alina Jucov, Christian Schwabe, Kha Le, Stanley Wang, Christopher Westland, Kim Steel, Qingling Zhang, Vikrant Gohil, Felix Lai, Meenakshi Venkatraman, Lawrence Blatt, Leonid Beigelman, Tse-I Lin, Sushmita Chanda, Matt McClure, John Fry
Journal: Journal of Hepatology (2022)
Understanding the dynamics of HBsAg decline through model-informed drug development (MIDD) of JNJ-3989 and JNJ-6379 for the treatment of chronic hepatitis B virus infection (CHB)
Authors: Huybrecht T’jollyn, Nele Goeyvaerts, Thomas Kakuda, Louis Sandra, Tetsuro Ogawa, Joris J Vandenbossche, Xavier Woot de Trixhe, Oliver Lenz, Ronald Kalmeijer, Michael Biermer, Juan Jose Perez Ruixo, Oliver Ackaert
Journal: Journal of Hepatology (2022)
Imaging moiety-directed co-assembly for biodegradation control with synchronous four-modal biotracking
Authors: Qingsong Liu, Ye Fu, Bin Wu, Jingyu Tang, Yaoben Wang, Yanping Wu, Man Zhang, Shen Shen, Yang Shen, Caiyun Gao, Jiandong Ding, Liangliang Zhu
Journal: Biomaterials (2022)
Hepatitis B virus-replicating transgenic mice exhibit a functional but restricted responsiveness to exogenous Tlr3 and Rig-I stimuli
Authors: Stefan Schefczyk, Xufeng Luo, Yaojie Liang, Mike Hasenberg, Bernd Walkenfort, Martin Trippler, Mengji Lu, Heiner Wedemeyer, Hartmut Schmidt, Ruth Broering
Journal: Journal of Hepatology (2022)
Simultaneous large spontaneous portosystemic shunt embolization for the prevention of overt hepatic encephalopathy after TIPS: a randomized controlled trial
Authors: Yong Lv, Hui Chen, Bohan Luo, Wei Bai, Kai Li, Zhengyu Wang, Dongdong Xia, Wengang Guo, Xiaomei Li, Jie Yuan, Zhanxin Yin, Daiming Fan, Guohong Han
Journal: Journal of Hepatology (2022)
Association of sustained virologic response with measures of direct-acting antiviral adherence in patients with Hepatitis C: data from the ASCEND and ANCHOR investigations
Authors: Sarah Kattakuzhy, Vivian Wang, Catherine Gannon, Sarah Mollenkopf, Charisse Ahmed, Sanjay Chainani, Junfeng Sun, Henry Masur, Shyamasundaran Kottilil, Elana Rosenthal
Journal: Journal of Hepatology (2022)
Restoring bone marrow hematopoietic stem cells (BM-HSC) reserve augments regression of fibrosis and regeneration in animal model of cirrhosis
Authors: Nidhi Nautiyal, Deepanshu Maheshwari, Pranshu E Rao, Sujata Mohanty, Anupama Parasar, Chhagan Bihari, Subhrajit Biswas, Rakhi Maiwall, Anupam Kumar, Shiv Kumar Sarin
Journal: Journal of Hepatology (2022)
The interplay between PCOS pathology and diet on gut microbiota in a mouse model
Authors: Valentina Rodriguez Paris, Xin Yi Denise Wong, Samantha M Solon-Biet, Melissa C Edwards, Ali Aflatounian, Robert B Gilchrist, Stephen J Simpson, David J Handelsman, Nadeem O Kaakoush, Kirsty A Walters
Journal: Gut Microbes (2022)

The gut microbiome has been implicated in polycystic ovary syndrome (PCOS) pathophysiology. PCOS is a disorder with reproductive, endocrine and metabolic irregularities, and several studies report that PCOS is associated with a decrease in microbial diversity and composition. Diet is an important regulator of the gut microbiome, as alterations in macronutrient composition impact the balance of gut microbial communities. This study investigated the interplay between macronutrient balance and PCOS on the gut microbiome of control and dihydrotestosterone (DHT)-induced PCOS-like mice exposed to diets that varied in protein (P), carbohydrate (C) and fat (F) content. The amount of dietary P, C and F consumed significantly altered alpha (α) and beta (β) diversity of the gut microbiota of control and PCOS-like mice. However, α-diversity between control and PCOS-like mice on the same diet did not differ significantly. In contrast, β-diversity was significantly altered by PCOS pathology. Further analysis identified an operational taxonomic unit (OTU) within Bacteroides (OTU3) with 99.2% similarity to Bacteroides acidifaciens, which is inversely associated with obesity, to be significantly decreased in PCOS-like mice. Additionally, this study investigated the role of the gut microbiome in the development of PCOS traits, whereby PCOS-like mice were transplanted with healthy fecal microbiota from control mice. Although the PCOS gut microbiome shifted toward that of control mice, PCOS traits were not ameliorated. Overall, these findings demonstrate that while diet exerts a stronger influence over gut microbiota diversity than PCOS pathology, overall gut microbiota composition is affected by PCOS pathology.
Antiviral treatment cessation in HBeAg negative chronic hepatitis B: clinical outcome is associated with increase in specific pro-inflammatory cytokines
Authors: Marte Holmberg, Dag Henrik Reikvam, Olav Dalgard, Hans Christian Dalsbotten Aass, Ellen Samuelsen, Niklas Björkström, Asgeir Johannessen
Journal: Journal of Hepatology (2022)
Zonated quantification of immunohistochemistry in steatotic livers
Authors: Cédric Peleman, Winnok De Vos, Isabel Pintelon, Ann Driessen, Christophe Van Steenkiste, Annelies Van Eyck, Luisa Vonghia, Joris De Man, Benedicte De Winter, Tom Vanden Berghe, Sven Francque, Wilhelmus Kwanten
Journal: Journal of Hepatology (2022)
Impact of predisposition and precipitants on the short-term prognosis among inpatients with chronic liver disease
Authors: Yan Zhang, Guohong Deng, Xian-Bo Wang, Xin Zheng, Yan Huang, Jinjun Chen, Zhong-Ji Meng, Yanhang Gao, Zhiping Qian, Feng Liu, Xiao-Bo Lu, Yu Shi, Yan Huadong, Zheng Yubao, Hai Li
Journal: Journal of Hepatology (2022)
Patients with decompensated cirrhosis and liver transplant recipients demonstrate poor humoral and cellular immune response against COVID-19 vaccine
Authors: Anand Kulkarni, Sasikala Mitnala, Sowmya Iyengar, Shashidhar Jaggaiahgari, Baqar Gora, Hardik Rugwani, Mithun Sharma, Nagaraja Rao Padaki, Nageshwar Reddy
Journal: Journal of Hepatology (2022)
Use of comedication in patients with hepatitis C and addiction or drug abuse treated with direc-acting antivirals: implication in drug-drug interactions
Authors: Juan Turnes, Antonio Garcia Herola, Ramón Morillo Verdugo, Marinela Mendez Pertuz, Cristina De Alvaro, Candido Hernández, Antoni Sicras-Mainar
Journal: Journal of Hepatology (2022)
Non-invasive tests for clinically significant portal hypertension after HCV-cure-individual patient data meta-analysis and validation
Authors: Georg Semmler, Sabela Lens, Elias Laurin Meyer, Anna Baiges, Edilmar Alvarado-Tapias, Elba Llop, Javier Martinez, Philipp Schwabl, Ezequiel Mauro, Laia Escude, Cristina Diez, Luis Ibañez, Jose Ignacio Fortea, Angela Puente, Marta Abadia, Ji-Dong Jia, Hitoshi Yoshiji, Sven Francque, Emmanuel Tsochatzis, Jaime Bosch, Rafael Bañares, Gonzalo Crespo, Thomas Reiberger, Càndid Villanueva, Xavier Forns, Juan Carlos Garcia Pagan, Mattias Mandorfer
Journal: Journal of Hepatology (2022)
The uptake of extracellular lipids promotes cholangiocarcinoma progression
Authors: Mikel Ruiz de Gauna, Francesca Biancaniello, Francisco González-Romero, Pedro Miguel Rodrigues, Ainhoa Lapitz, Beatriz Gómez Santos, Paula Olaizola, Sabina Di Matteo, Igor Aurrekoetxea, Ibone Labiano, Ane Nieva-Zuluaga, Asier Benito-Vicente, María Jesús Perugorria, Maider Apodaka-Biguri, Nuno Paiva, Diego Saenz de Urturi, Xabier Buque, Igotz Delgado, Cesar Augusto Martín, Mikel Azkargorta, Felix Elortza, Diego Calvisi, Jesper Andersen, Domenico Alvaro, Vincenzo Cardinale, Luis Bujanda, Jesus Maria Banales, Patricia Aspichueta
Journal: Journal of Hepatology (2022)
Confidence in treatment is contributing to quality of life in patients with autoimmune liver diseases. The results of ERN-RARE Liver online survey
Authors: Ewa Wunsch, Linda Krause, Tom Gevers, Christoph Schramm, Maciej K. Janik, Marcin Krawczyk, Natalie Uhlenbusch, Bernd Löwe, Ansgar W. Lohse, Piotr Milkiewicz
Journal: Journal of Hepatology (2022)