tbuckley/cabot-search huggingface dataset:
SLEEP PARALYSIS
Authors: JEROME M. SCHNECK
Journal: American Journal of Psychiatry (1952)

Sleep paralysis apparently occurs more frequently than reported cases would indicate. It has been mentioned mostly in association with narcolepsy and cataplexy. Psychodynamics involved has received relatively scant attention. The probable role of latent homosexual conflict in some instances had been reported previously by the present writer. In this report 2 cases of sleep paralysis are added to the somewhat sparse literature appearing in this country. In both these instances as well as in the writer's previous case narcolepsy and cataplexy were not part of the histories. Psychodynamics outlined now extends the items previously mentioned and indicates a parallel between the sleep paralysis and conflict over trends in the direction of over-all active, aggressive functioning and inactive, passive behavior.
Inflammatory Bowel Disease
Authors: H Herfarth, G Rogler
Journal: Endoscopy (2005)

This review summarizes important publications that have appeared during the last year dealing with imaging techniques and endoscopy, as well as the management of low-grade dysplasia and stenosis in inflammatory bowel disease. Magnetic resonance enteroclysis and capsule endoscopy are currently emerging as new imaging techniques for the small bowel in Crohn’s disease. While magnetic resonance enteroclysis is, at least in Europe, increasingly being used as a reference method, the value of capsule endoscopy for the management of inflammatory bowel disease is still being evaluated. Chromoendoscopy is being studied in patients with long-lasting ulcerative colitis and may be a promising and sensitive technique for the diagnosis of dysplasia. However, there are conflicting data regarding the appropriate management when low-grade dysplasia is diagnosed in patients with ulcerative colitis. Endoscopic dilation can often be successfully carried out in cases of intestinal stenosis. The results of long-term follow-up studies indicate that several dilation procedures are often necessary and that a relatively high percentage of patients still have to undergo surgery.
Conferences on Drug Addiction among Adolescents.
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Traumatic Surgery.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
What's new in the other general journals
Authors: Alison Tonks
Journal: BMJ (2006)

Yet more evidence has emerged that staying active in old age is linked to prolonged survival. In a study of 302 elderly US adults, burning more energy was associated with a significantly lower risk of death over a mean follow-up of six years—every extra 1.2 MJ (287 kcal) a day cutting the risk by about 30%. The most active participants were substantially and significantly less likely to die during follow-up than the least active (hazard ratio comparing top and bottom thirds of energy expenditure, 0.33 (95% CI 0.15 to 0.74)) even accounting for age, sex, race, weight, height, percentage of body fat, sleep duration, smoking habit, education, and health. Credit: JAMA The authors used doubly radiolabelled water to measure energy expenditure, then computed a figure for energy burnt during activity by subtracting the basal metabolic rate and allowing for the thermic effects of eating. The most active participants burnt 603 more “activity” calories a day than the least active. Less than half the difference was due to extra exercise. They burnt the rest simply moving around, fidgeting, and generally getting on with life. Credit: JAMA Although these results are fairly striking, they don't translate easily into specific public health messages, writes a linked editorial (pp 216-8). Next time, researchers should try to record the intensity of people's activity too, preferably using an objective method such as accelerometry. JAMA 2006296171–9 [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] Twenty years ago, most people accepted that childhood autism was a rare developmental disorder with a prevalence of about four or five per 10 000 children. Japanese researchers were the first to notice an increase in the late 1980s. Europeans and Americans followed suit a decade later, and the prevalence has continued to rise since then, with 116 per 10 000, or more than 1%, of children having an autistic spectrum disorder in … [1]: {openurl}?query=rft.jtitle%253DJAMA%26rft.stitle%253DJAMA%26rft.issn%253D0002-9955%26rft.aulast%253DManini%26rft.auinit1%253DT.%2BM.%26rft.volume%253D296%26rft.issue%253D2%26rft.spage%253D171%26rft.epage%253D179%26rft.atitle%253DDaily%2Bactivity%2Benergy%2Bexpenditure%2Band%2Bmortality%2Bamong%2Bolder%2Badults.%26rft_id%253Dinfo%253Adoi%252F10.1001%252Fjama.296.2.171%26rft_id%253Dinfo%253Apmid%252F16835422%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1001/jama.296.2.171&link_type=DOI [3]: /lookup/external-ref?access_num=16835422&link_type=MED&atom=%2Fbmj%2F333%2F7560%2F192.atom [4]: /lookup/external-ref?access_num=000238946500022&link_type=ISI
RESEARCH IN EPILEPSY
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Deutsche Medizinische Wochenschrift, Stuttgart
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Antibiotics for otitis media: a clarification
Authors: R. M. Rosenfeld
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Introduction: Methods For Environmental Quantitative Risk Assessment
Authors: Carol Redmond, Joseph Costantino
Journal: Environmental Health Perspectives (1991)

The objective ofthe organizers was to develop a program that would present recent advances in methodologies for assessing health risk for environmental exposures; provide health researchers with information useful to evaluate the impact ofenvironmental exposures; and assess the evidence for human health effects from exposures to selected environmental pollutants.To accomplish these objectives the symposium was divided into five sessions, each dealing with a specific issue relevant to quantitative risk assessment of environmental exposures.The session topics included: (1) "Methodological Issues in Quantitative Risk Assessment of Reproductive Effects"; (2) "Appraisal ofCurrent Methodologies for Measuring Exposures and Health Outcomes"; (3) "Statistical Issues in Quantitative Risk Assessment"; and (4) "Use of Biological Markers for Quantitative Risk Assessment."Individuals with particular expertise relevant to these topics were invited to be symposium presenters or discussants.The following proceedings contain the manuscripts of presentations made by these individuals.
Abstract 4287: Peroxiredoxin 2 has a crucial role in the survival of gastric cancer cells by regulating β-catenin and TNF signaling
Authors: Hee Sung Kim, Tae Hyeong Lee, Dong Hoon Kang, Peter Chang-Whan Lee, Byung Sik Kim
Journal: Cancer Research (2019)

Abstract Gastric cancer (GC) is globally the fifth most common cancer and third leading cause of cancer death. Functional activation of β-catenin is necessary for early events in gastric carcinogenesis and GC with mutation of APC gene, similar to colorectal tumorigenesis, occur during the early stages of gastric adenoma development. Mammalian 2-Cys peroxiredoxin (Prx) enzymes are overexpressed in most cancer tissues, but the effect of Prx2 expression on GC survival remains unclear. Here, we demonstrate that Prx2 deletion markedly reduces the active β-catenin levels and the expression of β-catenin target genes in GC cells. Furthermore, the TNF α-induced activation of ERK1/2 was inhibited and reciprocally, JNK phosphorylation and cleaved caspase3 was increased in Prx2-knockdown GC cells. Prx2 deletion also can suppress the viability, invasion and colony formation of GC cells. The proof-of-concept experiment using conoidinA as a Prx2 inhibitor shows it can significantly ablates the growth of 5-FU-resistant SNU620. Thus, our findings reveal that Prx2 is a key regulator of β-catenin and TNF signaling pathway in GC, and also suggest a pharmacologic strategy to effectively overcome drug-resistant GC. Note: This abstract was not presented at the meeting. Citation Format: Hee Sung Kim, Tae Hyeong Lee, Dong Hoon Kang, Peter Chang-Whan Lee, Byung Sik Kim. Peroxiredoxin 2 has a crucial role in the survival of gastric cancer cells by regulating β-catenin and TNF signaling [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4287.
Inhibition of Adrenocortical Carcinoma Cell Proliferation by Steroidogenic Factor-1 Inverse Agonists
Authors: Mabrouka Doghman, Julie Cazareth, Dominique Douguet, Franck Madoux, Peter Hodder, Enzo Lalli
Journal: Endocrine Reviews (2009)

ABSTRACT Context: Transcription factor steroidogenic factor-1 (SF-1) plays a pivotal role in the control of adrenocortical cell steroidogenesis and proliferation. SF-1 amplification and overexpression are found in most cases of childhood adrenocortical tumors (ACTs). Objective: Our objective was to investigate the effect of SF-1 inverse agonists of the alkyloxyphenol and isoquinolinone classes on the proliferation of human adrenocortical cell lines expressing SF-1 (H295R), in conditions of basal and increased SF-1 expression, or negative for SF-1 expression (SW-13). Main Outcome Measures: Proliferation assays, immunoblots, flow cytometric analyses, steroid hormone assays, and real-time quantitative PCR were used. Results: SF-1 inhibitors of the alkyloxyphenol class displayed a dose-dependent inhibitory effect on both SF-1-positive and -negative ACT cells, whereas SF-1 inverse agonists of the isoquinolinone class selectively inhibited cell proliferation elicited by SF-1 overexpression. These drugs also inhibited stimulated steroid hormone secretion and CYP21 and CYP17 mRNA expression. Conclusion: SF-1 inhibitors may represent a useful tool in the chemotherapy of ACTs.
FREAK LEGISLATION.
Journal: JAMA (2007)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ranking the Potential Carcinogenic Hazards to Workers from Exposures to Chemicals That Are Tumorigenic in Rodents
Authors: Lois Swirsky Gold, Georganne M. Backman, N. Kim Hooper, Richard Peto
Journal: Environmental Health Perspectives (1987)

For 41 chemicals there exist both reasonable data on carcinogenic potency in experimental animals and also a defined Permissible Exposure Level (PEL), which is the upper limit of legally permissible chronic occupational exposure for U.S. workers. These 41 agents are ranked by an index that compares the permitted chronic human exposure to the chronic dose rate that induces tumors in 50% of laboratory animals. This index, the Permitted Exposure/Rodent Potency index, or PERP, does not estimate absolute risks directly, but rather suggests the relative hazards that such substances may pose. The PERP values for these 41 substances differ by more than 100,000-fold from each other. The PERP does not take into account the actual level of exposure or the number of exposed workers. Nevertheless, it might be reasonable to give priority attention to the reduction of allowable worker exposures to substances that appear most hazardous by this index and that some workers may be exposed to full-time near the PEL. Ranked by PERP, these chemicals are: ethylene dibromide, ethylene dichloride, 1,3-butadiene, tetrachloroethylene, propylene oxide, chloroform, formaldehyde, methylene chloride, dioxane, and benzene.
B.M.A. Annual Meeting, Sydney, 10-16 August: Report of Proceedings
Journal: BMJ (1968)

The One Hundred and Thirty-sixth Annual Meeting of the British Medical Association was held in Sydney from 10 to 16 August jointly with the Seventh Annual Meeting of the Australian Medical Association. Both meetings were associated with the Third Australian Medical Congress. It was the second Annual Meeting of the Association to be held in Australia, the previous one having been in Melbourne in 1935. Four plenary sessions were held on successive mornings, while meetings of various sections were held in the afternoons. An account of the first part of the Meeting is given below. The remainder will be reported next week.
AN ANALYSIS OF THE STATISTICS OF FORTY-ONE THOUSAND FIVE HUNDRED CASES OF EPIDEMIC INFLUENZA
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chronic fatigue syndrome and the diagnostic utility of antibody to Epstein-Barr virus early antigen
Authors: W. C. Hellinger
Journal: JAMA (1988)

Antibody to Epstein-Barr virus (EBV) early antigen has been said to be the most specific indicator of symptomatic chronic EBV infection. We studied the clinical utility of this serologic test in the evaluation of patients with chronic fatigue. Thirty patients with chronic fatigue and highly elevated titers of antibody to early antigen (≥1:160) were compared with 30 age- and sex-matched controls with no antibody to early antigen. There were no significant differences noted between patients and controls at the initial evaluation (symptoms, physical examination, laboratory data). Follow-up information, available for 15 matched pairs, showed no differences in outcome between patients and controls. We conclude that the antibody to EBV early antigen is not helpful in the clinical evaluation of patients with chronic fatigue. (<i>JAMA</i>1988;260:971-973)
EuroQoL EQ-5D is a practical measure of population health
Journal: BMJ (1998)

Ultrasound treatment relieves pain in carpal tunnel syndromeNo effective conservative treatment exists for carpal tunnel syndrome, and surgical decompression is often performed.In a randomised, "sham" controlled study of an intensive schedule of 20 sessions of ultrasound treatment, Ebenbichler et al (p 731) found that treatment led to short and medium term relief of pain and neurological symptoms in patients with mild to moderate forms of the syndrome.Optimal schedules of ultrasound treatment used alone or in combination with other medical treatments await elucidation.Long term efficacy is yet to be determined.
Vergleichende Anatomie des Nervensystems. Erster Teil: Die Leitungsbahnen Im Nervensystem der Wirbellosen Tiere.
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal