tbuckley/cabot-search huggingface dataset:
THE SURGICAL TREATMENT OF GENERAL PARALYSIS OF THE INSANE
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INFLUENZA AND GENERAL MORTALITY.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
(21) Partial lipodystrophy
Authors: B.R. Allen
Journal: British Journal of Dermatology (1978)

Journal Article (21) Partial lipodystrophy Get access B.R. Allen B.R. Allen General Hospital, Nottingham Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 99, Issue s16, 1 December 1978, Pages 48–49, https://doi.org/10.1111/j.1365-2133.1978.tb15243.x Published: 01 December 1978
Chemotherapy-induced neutropenia association with survival in metastatic colorectal cancer (MCC): Schedule dependency.
Authors: P. F. Innominato, S. Giacchetti, R. Smaaland, C. N. Focan, C. Garufi, G. A. Bjarnason, S. Iacobelli, S. Tumolo, A. Karaboué, F. Levi
Journal: Journal of Clinical Oncology (2011)

454 Background: Circadian clocks control cellular proliferation and drug metabolism over 24 h. However, circadian chronomodulated chemotherapy with 5-fluorouracil, leucovorin and oxaliplatin (chronoFLO4) offered no survival benefit as compared to the non-time stipulated FOLFOX2 in an international randomized trial involving patients (pts) with previously untreated MCC (EORTC05963). We hypothesized that treatment near maximum tolerated dose could disrupt circadian clocks thus impairing the efficacy of chronoFLO4 but not of FOLFOX2. Methods: Pts with available data (N=556) were categorized into three subgroups according to the worst grade of neutropenia experienced during treatment. Distinct multivariate models were constructed for each treatment schedule. Results: Neutropenia (all grades) occurred in 39% of the pts on chronoFLO4 as compared to 67% of those on FOLFOX2 (p&lt; 0.0001), with G3-4 being encountered in 7% and 25%, respectively (p&lt; 0.0001). In both schedules, neutropenia was more frequent and more severe in women than in men (p&lt;0.04).The occurrence (but not the severity) of neutropenia was significantly associated with improved objective response rate, progression-free and overall survival in pts on FOLFOX2 (p&lt; 0.0001), confirming previous results by others. In pts on chronoFLO4, the occurrence of neutropenia was not associated with any efficacy advantage (p=0.36), and worst survival was observed in pts developing severe neutropenia. Conclusions: Neutropenia was more frequent and severe in women than in men, and on FOLFOX2 than on chronoFLO4. Neutropenia was positively correlated with survival in pts on FOLFOX2 supporting intra-patient dose escalation to achieve toxicity for conventional chemotherapy. No survival prolongation was found in pts with neutropenia on chronoFLO4. Thus, reaching maximum tolerated dose was unnecessary to achieve optimal effectiveness of circadian-timed therapy, and should even be avoided. [Table: see text] No significant financial relationships to disclose.
MERCURIC CHLORID POISONING FROM VAGINAL INJECTIONS—TWO FATAL
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fringe Benefits on the Fringes of Civilization
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nutritive Allergie in der Pathogenese innerer Erkrankungen ALS nährschaden Erwachsener.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dietary Vitamin A Intake and Risk for Hip Fracture
Authors: Håkan Melhus, Karl Michaëlsson, Andreas Kindmark
Journal: Annals of Internal Medicine (1999)

Letters7 September 1999Dietary Vitamin A Intake and Risk for Hip FractureHåkan Melhus, MD, PhD, Karl Michaëlsson, MD, PhD, and Andreas Kindmark, MD, PhDHåkan Melhus, MD, PhDUppsala University Hospital; Uppsala, Sweden S-751 20 (Melhus)Uppsala University Hospital; Uppsala, Sweden S-751 20 (Michaëlsson)Uppsala University Hospital; Uppsala, Sweden S-751 20 (Kindmark)Search for more papers by this author, Karl Michaëlsson, MD, PhDUppsala University Hospital; Uppsala, Sweden S-751 20 (Melhus)Uppsala University Hospital; Uppsala, Sweden S-751 20 (Michaëlsson)Uppsala University Hospital; Uppsala, Sweden S-751 20 (Kindmark)Search for more papers by this author, and Andreas Kindmark, MD, PhDUppsala University Hospital; Uppsala, Sweden S-751 20 (Melhus)Uppsala University Hospital; Uppsala, Sweden S-751 20 (Michaëlsson)Uppsala University Hospital; Uppsala, Sweden S-751 20 (Kindmark)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-5-199909070-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Sigurdsson would like clarification of the covariates that made the effect of retinol significant in the multivariate analysis in the bone mineral density study. He would also like to see the results after adjustment for vitamin D intake.We tried to include the same set of covariates in both the hip fracture and bone mineral density studies (established osteoporosis risk factors). No major confounding was observed in the hip fracture study, but in the linear regression analysis of the bone density study, inclusion of possible confounders did change our estimates. Energy intake was the covariate with the ... Author, Article, and Disclosure InformationAffiliations: Uppsala University Hospital; Uppsala, Sweden S-751 20 (Melhus)Uppsala University Hospital; Uppsala, Sweden S-751 20 (Michaëlsson)Uppsala University Hospital; Uppsala, Sweden S-751 20 (Kindmark) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoExcessive Dietary Intake of Vitamin A Is Associated with Reduced Bone Mineral Density and Increased Risk for Hip Fracture Hakan Melhus , Karl Michaelsson , Andreas Kindmark , Reinhold Bergstrom , Lars Holmberg , Hans Mallmin , Alicja Wolk , and Sverker Ljunghall Dietary Vitamin A Intake and Risk for Hip Fracture Gunner Sigurdsson Metrics 7 September 1999Volume 131, Issue 5Page: 392KeywordsBone densityHip fracturesLinear regression analysisMedical risk factorsMultivariate analysisNutrientsOsteoporosisVitamin AVitamin D ePublished: 15 August 2000 Issue Published: 7 September 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Error in Abstract
Journal: JAMA Neurology (2017)

Justin C. Kao, MBChB; Bing Liao, MD, PhD; Svetomir N. Markovic, MD, PhD; Christopher J. Klein, MD; Elie Naddaf, MD; Nathan P. Staff, MD, PhD; Teerin Liewluck, MD; Julie E. Hammack, MD; Paola Sandroni, MD, PhD; Heidi Finnes, PharmD, RPh; Michelle L. Mauermann, MD
From black bag to black box: will computers improve the NHS?
Authors: L. J Donaldson
Journal: BMJ (1996)

Influenza virus infection causes seasonal epidemics and occasional pandemics, leading to huge morbidity and mortality worldwide. Vaccination against influenza is needed annually as protection from constantly mutating strains is required. Groups at high risk of poor outcomes include the elderly, the very young, pregnant women and those with chronic health conditions. However, vaccine effectiveness in the elderly is generally poor due to immunosenescence and may be altered due to “original antigenic sin”. Strategies to overcome these challenges in the elderly include high-dose or adjuvant vaccines. Other options include vaccinating healthcare workers and children as this reduces community-level influenza transmission. Current guidelines in the UK are that young children receive a live attenuated nasal spray vaccine, adults aged &gt;65 years receive an adjuvanted trivalent inactivated vaccine and adults aged &lt;65 years with comorbidities receive a quadrivalent inactivated vaccine. The goal of a universal influenza vaccine targeting conserved regions of the virus and avoiding the need for annual vaccination is edging closer with early-phase trials under way.
New Approaches to Antiarrhythmic Therapy, Part I
Journal: Circulation (2001)

Cardiac arrhythmias complicate many diseases affecting the heart and circulation, and they incorporate a multiplicity of underlying mechanisms. The evolution of scientific knowledge has made the complex changes produced by cardiovascular disease sufficiently understood at the organ, cellular, and molecular levels such that there is a diversity of therapeutic targets for pharmacological therapy and/or prevention. Moreover, the approach of rational drug design in mechanism-specific and disease-specific fashions facilitates the targeting of therapy using the methods of molecular, structural, and translational biology. Additional approaches, using similar drug design strategies but based on gene therapy and transcriptional and translational modification, are on the horizon. Hence, there is reason to be optimistic regarding the design, testing, and clinical availability of novel antiarrhythmic therapies.
THE BUSINESS INTERESTS OF AMERICA NOW DEMAND THE UNITED STATES PUBLIC HEALTH SERVICE.
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PRESCRIPTION GRAFT.
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
This Week in <EMPH>JAMA</EMPH>
Journal: JAMA (2006)

A Piece of My Mind"I knew the medicine dripping into my veins was going to make me feel bad, very bad, for weeks at a time."From "Taking My Poison." SEE PAGE 2657 Medical News & PerspectivesThe conclusion from a large multicenter study that the risk of miscarriage following amniocentesis is far lower than previously believed may reassure physicians and their patients and lead to increased prenatal screening.
Generation gap
Authors: C. D. Aring
Journal: JAMA (1972)

"Some day, maybe, there will exist a well-informed, wellconsidered, and yet fervent public conviction that the most deadly of all possible sins is the mutilation of a child's spirit; for such mutilation undercuts the life principle of trust, without which every human act, may it feel ever so good and seem ever so right, is prone to perversion by destructive forms of conscientiousness." Erik Erikson It might be that adults are the inadvertent models of noncommunication between the generations. While the succeeding generations may originate, they hardly do so in a vacuum. "Generation gap" resounds with such frequency these days that it is already a cliché; although, any break between generations, even a break in communication only, could be the swan song of humanity. The formative years are as good a place as any to examine for reasons that the generations do not communicate. Looking back to childhood—and one rarely
Magnetic Resonance Imaging Update and New Techniques: A Mini-Symposium
Journal: JNCI Journal of the National Cancer Institute (1987)

Magnetic Resonance Imaging Update and New Techniques: A Mini-Symposium Get access JNCI: Journal of the National Cancer Institute, Volume 78, Issue 6, June 1987, Page 1253, https://doi.org/10.1093/jnci/78.6.1253-e Published: 01 June 1987
Effect of topical tretinoin on non-sun-exposed human skin connective tissue: induction of tenascin but no major effect on collagen metabolism
Authors: K.-M. HAAPASAARI, M. KALLIOINEN, K. TASANEN, M. SUTINEN, A.P ANNALA, J. RISTELI, A. OIKARINEN
Journal: British Journal of Dermatology (1997)
THE " BREATHING " HOSPITAL.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effect of oral propranolol administration on azygos, renal and hepatic uptake and output of catecholamines in cirrhosis
Authors: F Bendtsen
Journal: Hepatology (1991)

Circulating catecholamines are increased in cirrhosis with portal hypertension, and increase further after propranolol. In 23 cirrhotic patients, plasma norepinephrine and epinephrine were determined in an artery, the azygos vein, the right renal vein and a hepatic vein before and after an oral 80-mg dose of propranolol. Baseline azygos and renal venous norepinephrine levels were significantly higher than arterial norepinephrine levels (+ 20%, p < 0.005; and + 28%, p < 0.001, respectively). Hepatic venous norepinephrine and all venous epinephrine values were below the arterial values (all p < 0.05). After propranolol intake, arterial norepinephrine and epinephrine increased (+ 16%, p < 0.01; and + 93%, p < 0.001, respectively). Significant increases in norepinephrine and epinephrine were found in azygos and renal veins (all p < 0.01), whereas hepatic venous norepinephrine and epinephrine remained unchanged. Azygos and hepatic blood flow decreased after propranolol intake (−27%, p < 0.05; and − 16%, p < 0.01, respectively). Azygos spillover of norepinephrine (an estimate of locally released norepinephrine delivered to the circulation) and clearance of epinephrine remained unaltered. Hepatointestinal clearance showed no significant change for norepinephrine, but showed a borderline-significant decrease for epinephrine (−23%, p = 0.08). Our results show a net production of norepinephrine in the prehepatic splanchnic area drained through superior portalsystemic collaterals and in the kidneys. The increase in circulating catecholamines after propranolol intake is probably due to a combination of further enhancement of sympathetic activity and a decrease in catecholamine degradation. (HEPATOLOGY 1991;14:237–243.)
Conference on the Interaction of Radiation Therapy and Chemotherapy
Journal: JNCI Journal of the National Cancer Institute (1986)

Conference on the Interaction of Radiation Therapy and Chemotherapy Get access JNCI: Journal of the National Cancer Institute, Volume 76, Issue 5, May 1986, Page 981, https://doi.org/10.1093/jnci/76.5.981-e Published: 01 May 1986