tbuckley/cabot-search huggingface dataset:
Atypical Cough Syncope
Authors: Michael J. Strauss
Journal: JAMA (1984)

TUSSIVE or cough syncope is an uncommon but easily recognized syndrome. The typical case is benign and does not require extensive evaluation. We report an atypical case of cough syncope that was associated with marked stenoses of both common carotid arteries and that improved with surgery. We review the literature, with particular attention to cases with correctable lesions. <h3>Report of a Case</h3> A 51-year-old man complained of six months of cough syncope. During spontaneous and prolonged coughing, he would lose consciousness for seconds to minutes. His attacks occurred almost daily. He smoked but was receiving no medications. He had a medical history of hypertension, chronic alcoholism, and angina that led to a single-vessel coronary artery bypass. Physical examination of this normotensive man was remarkable for obesity and bilateral carotid bruits. Provocative maneuvers, such as forced coughing or Valsalva, could not reproduce the syncope. A chest roentgenogram was unremarkable. An ECG
Persistent Macrocytosis Following Abstinence From Chronic Alcohol Use
Authors: Martin Hasselblatt
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The coroner service
Authors: J. Pilpel, R. Charlton, M. Samuels, A. Sheikh, A R Gatrad, S. Dhami, J. Levitan, B. K Dines
Journal: BMJ (1999)

# Coroner service could indeed be improved {#article-title-2} EDITOR—I recognise the need for society and the judiciary to be able to check up on medical practitioners, but I strongly concur with Pounder's views that the coroner service could be improved.1 A 49 year old patient of the practice where I work died peacefully at home recently of cerebral metastases from lung cancer. He had been ably cared for by his wife and daughters with help from the district and hospice nurses in liaison with one of my partners and our local oncologist. I attended to confirm death, but as he had not needed to see a doctor in the last month or so the coroner would not permit me to issue the death certificate. After some negotiation and despite being sympathetic, he did consent to my partner issuing the death certificate on her return from holiday four days later, although he would not have done so had she not been due back so soon. There seemed no doubt about our patient's identity or place or cause of death, and there certainly was no hint of foul play. This case is by no means an isolated one, and I am sure that many of my general practitioner colleagues are tempted to overlook the rules in straightforward natural deaths to protect relatives from interference. I believe that the public would welcome the opportunity to express their views and am equally sure that they would support modernisation of this archaic but important service. 1. 1.↵1. Pounder D . The coroner service. BMJ 1999; 318: 1502–1503. (5 June.) [OpenUrl][1][FREE Full Text][2] # Inquests often facilitate grief {#article-title-4} EDITOR—Pounder's editorial on the coroner service fails to raise important issues in relation to bereavement and the existing coroner service.1 There is a conflict of interest between the “enforceable intrusion” of a coroner's inquest … [1]: {openurl}?query=rft.jtitle%253DBMJ%26rft.stitle%253DBMJ%26rft.issn%253D0007-1447%26rft.aulast%253DPounder%26rft.auinit1%253DD.%26rft.volume%253D318%26rft.issue%253D7197%26rft.spage%253D1502%26rft.epage%253D1503%26rft.atitle%253DThe%2Bcoroner%2Bservice%26rft_id%253Dinfo%253Apmid%252F10355984%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=FULL&journalCode=bmj&resid=318/7197/1502&atom=%2Fbmj%2F319%2F7216%2F1072.atom
Venn Diagrams in Drug Abuse Education
Authors: Richard P. Wenzel
Journal: JAMA (1972)

<h3>To the Editor.—</h3> Lipinski's lucid article, "Motivation in Drug Misuse,"<sup>1</sup>prompts my note concerning drug abuse education on this military base. Because of our interest in the epidemiology of viral hepatitis and drug usage, the command has asked us to contribute to the medical section (nine hours) of a 36-hour drug abuse course offered to higher-ranking enlisted men and officers. In the ten months of continuing education, two questions directed to the medical officer remain most urgent to our students: (1) What are some of the causes of drug abuse? (2) What are possible approaches to this problem? In an attempt to present lasting concepts in a brief period of teaching, I have used a model borrowed from set theory. Three sets are presented and illustrated by Venn diagrams: (1) the set of all men with unfavorable psychosocial factors predisposing to drug abuse; (2) the set of all men
Management of Ventricular Tachyarrhythmias
Authors: Masood Akhtar
Journal: JAMA (1982)

VENTRICULAR tachyarrhythmias represent a substantial management problem in clinical practice, frequently posing a diagnostic and therapeutic dilemma in critical, often life-threatening circumstances. In this article, the current concepts and approaches to the management of ventricular arrhythmias will be addressed. Traditionally, ventricular arrhythmias are defined as abnormal impulses originating from areas below the division of the His bundle and may take the form of isolated ventricular premature beats (VPBs) or be more sustained. A ventricular rhythm lasting for three or more complexes with a rate of 100 to 250/min is called ventricular tachycardia (VT). Although hemodynamic deterioration frequently results, an organized and effective ventricular contraction pattern is usually maintained during VT unless the rates are exceedingly fast. When ventricular activation is rapid and chaotic, it is referred to as ventricular fibrillation (VF), the hemodynamic consequences of which are catastrophic, and is therefore considered to be the most malignant of all ventricular
Regulations on registration of a fetus papyraceus need to be revised
Authors: R. F Heys
Journal: BMJ (1997)

Introducing the postoperative care team Effective postoperative care remains surgeons' roleEditor-I am concerned that the suggestions made by David R Goldhill might be taken too seriously rather than remain a point for discussion. 1 Goldhill is right in his assertion that patients can fare badly in their postoperative course because of lack of attention by their attendants and lack of understanding of common postoperative complications.I believe, however, that he has missed the opportunity to lay the blame at the correct door.Surely it is the surgeons' role to carry out preoperative assessment, surgery, and effective postoperative care.If they choose to emphasise their importance in the operating theatre, delegating their other responsibilities to their trainees, the nurse practitioners, and the anaesthetists, why should we encourage this path?Undoubtedly, anaesthetists are fast becoming the new generalists, with an increasing role outside the operating theatre.These new skills and responsibilities include pain control, intensive care, and transoesophageal echocardiography, to name but a few.Some of my professional colleagues may relish even more diversification and abhor my comments.Goldhill implies that anaesthetists and postoperative care nurses will lead the postoperative care team; indeed, this is already happening in North America, where they have been sent to run preoperative assessment clinics by surgeons based in the operating room.If the surgical ward round in your hospital has become a quick look through the laboratory results and a glance at the chest radiograph before a rush to the changing rooms then I suggest that waiting for the confidential inquiry into perioperative deaths to point out the obvious is not the solution.
The Two-Phalanged Fifth Toe
Authors: John G. Short
Journal: JAMA (1968)

<h3>To the Editor:</h3> The presence of only two phalanges in the fifth toe is a more common variant than is generally appreciated. Asin reported an incidence of 48% in 417 patients studied by roentgenograms.<sup>1</sup> <h3>Material and Methods:</h3> The foot roentgenograms of 393 patients, 12 years of age or older, were reviewed. The i. majority of patients had roentgenograms obtained of only one foot. However, 26 patients were examined bilaterally. These patients were either normal bilaterally or had only two-phalanged fifth toes bilaterally except for three patients who had normal right fifth toes and two-phalanged left fifth toes. These three patients were not considered in either group. None of the patients had any generalized or localized bone anomalies, and the majority of the roentgenograms were obtained because of trauma. <h3>Results:</h3> There were 390 patients considered and 188 patients (48.2%) demonstrated only two phalanges in their fifth toes (Fig. 1). A
The British Society of Gastroenterology
Authors: R Brown, M Langman, M Keighley, P Asquith
Journal: Gut (1974)

The spring meeting was held at the University of Nottingham on 29 and 30 March 1974.The first morning was devoted to informal discussion groups, one of which was on 'Histopathology of the alimentary tract' (Chairman: Professor Ian Dawson) and the other on 'Primary liver cancer' (Chairman: Professor Sheila Sherlock).The whole of Saturday morning, 30 March, was devoted to a symposium on 'Colonic function'.During the afternoon of both days there were sessions devoted to free papers of which abstracts follow.
Late breaking abstracts
Journal: Hepatology (2005)

Background: In a Phase IIb trial telbivudine (LdT) demonstrated greater HBV suppression and ALT normalization than lamivudine (Lai, Gastroenterology 2005).Here we report results from a large Phase III trial of LdT vs lamivudine.Methods: The GLOBE study is a randomized blinded 2-yr trial comparing telbivudine (600 mg/d PO) vs standard lamivudine (Lam, 100 mg/d PO) in an intent-to-treat population of 1,367 adults with chronic hepatitis B from 112 clinical centers internationally.Key entry criteria were HBsAgϩ, HBV DNA Ͼ6 log10 copies/mL by COBAS PCR assay, ALT 1.3-10 xULN, and compensated liver disease.Patients (pts) were stratified for HBeAg status (ϩ or -) and ALT Ͻ or Ͼ 2.5 xULN.The primary analysis is at Week 52 (W52) with later analyses at W76 and W104.Results: Treatment groups were well-matched at Baseline.Efficacy data for all pts at W52: Efficacy Results: LdT was superior to Lam (pϽ 0.01) at W52 for all virus-related efficacy parameters in both patient groups.For the primary efficacy endpoint (Therapeutic Response, defined as HBV DNA Ͻ 5 log10 with HBeAg loss or ALT normalization), LdT was superior to Lam in the HBeAgϩ group.The study drugs were similar on this endpoint in HBeAg-patients at W52, despite greater antiviral efficacy for LdT in this group.Treatment failure and resistance were more ϭcommon with Lam in both groups.Available data for 398 pts at W76 suggest that advantages for LdT may increase during the 2 nd year.At W76, for LdT vs Lam, HBeAg loss is 39% vs 28%, Therapeutic Response is 81% vs 64%, PCR-neg is 73% vs 45%, and ALT normalization is higher for LdT in both groups (no statistics on preliminary W76 data).Histology results will be available at the meeting.Safety Results: Both drugs were well-tolerated with similar adverse event profiles.ALT flares, mostly associated with resistance, were more common with Lam (5%, vs Ͻ1% for LdT).Severe ALT flares (ALTϾ10x ULN and bilirubin Ͼ2x ULN) occurred in 3 patients receiving Lam, with none in LdT recipients.Transient CK elevations, not requiring treatment modification, were more common with LdT (9% vs 3% for Lam).Conclusions: After 1 year, telbivudine demonstrated significantly greater antiviral efficacy than lamivudine in both HBeAgϩ and HBeAg-patients, with less primary treatment failure and less resistance, and with fewer and less severe ALT flares.Response HBeAg ؉ LdT Lam HBeAg -LdT Lam n 458 463 222 224 † HBV DNA never Ͻ5 log10 copies/mL (per AASLD guideline) * pϽ 0.01, LdT vs Lam, at W52Disclosures: Ching-Lung Lai -Consultant for: Idenix Pharmaceuticals, Discussion will include offlabel / investigative use of medicine(s), medical devices or procedure(s) Edward Gane -No relationships to disclose
NON-A, NON-B HEPATITIS VIRUS
Authors: Philippe Pouletty, Jean Kadouche, Philippe Lebacq, B. Seto, R.J. Gerety, W.G. Coleman, S. Iwarson, Gioacchino Angarano, Giuseppe Pastore, Laura Monno, Teresa Santantonio, Oronzo Schiraldi, Evelyn Dermott, AlfredM. Prince, Tellervo Huima, BolanleA.A. Williams, Luda Bardina, Betsy Brotman, Sten Iwarson, Zsuzsa Schaff, Freddie Mitchell, R.J. Gerety
Journal: The Lancet (1985)
Use of the Passive Voice
Authors: Nicholas P. Christy
Journal: JAMA (1985)

<h3>To the Editor.—</h3> James Ransom<sup>1</sup>has lately advised readers to "use the passive voice." If all medical writers were well-trained, skillful, and judicious verbal craftsmen and if they all cared deeply about the communicative quality and intensity of what they write, I might agree with Dr Ransom that they should use the passive where appropriate. But how will they judge where it is appropriate? Experienced readers of medical prose know that their colleagues exert no such judgment. They just use the passive voice all the time. The reasons, given in detail elsewhere,<sup>2</sup>are these: the force of tradition, the need to conform, the wish to appear formal, impersonal, and "scientific," and a craven desire to place the maximum distance between the work done and the doer of it. A little history may reveal some truths about the passive. Many commentators think its widespread use derives from the influence
Characterization of an <italic>In Vitro</italic> Strain of Ehrlich-Lettre Ascites Carcinoma Subjected to Many Periodic Mouse Passages
Authors: Charles Boone, Motomichi Sasaki, Ralph W. McKee
Journal: JNCI Journal of the National Cancer Institute (1965)

An in vitro strain of Ehrlich-Lettre ascites carcinoma, designated E, was subjected to a schedule of 7 mouse passages over a period of 17 months. In addition to retaining a degree of malignancy approaching that of the parental Ehrlich tumor, strain E developed high explantability, i.e., when it was passed through a series of mice and then explanted back into culture vessels, most cells survived in vitro and began growing exponentially within 24 hours, in contrast to the extensive degeneration accompanying explantation of the stock Ehrlich-Lettre ascites tumor cells. Solid tumors produced by strain E cells closely resembled solid tumors produced by the Ehrlich-Lettre cells. Cytogenetically, strain E was characterized by an unusually high mean chromosome number of near 120 and by the retention of marker chromosomes present in the parental Ehrlich tumor. A clone in strain E not containing the specific marker chromosome “A” characteristic of the Ehrlich-Lettre ascites tumor still produced typical ascites tumors.
MEDICAL EDUCATION IN THE UNITED STATES AND CANADA.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Postpolio Syndrome May Not Be Progressive
Authors: Charles Marwick
Journal: JAMA (1992)

THE SYMPTOMS of fatigue, weakness, and pain that characterize the so-called postpolio syndrome—which a few years ago seemed to be growing more severe among persons who have had poliomyelitis (<i>JAMA</i>. 1986;255:1397-1399,1403-1404, 1541-1546, 1547)—may not continue on a downhill course. This is the indication from the first 5-year follow-up of 10 persons in the 50-subject study of postpolio patients being conducted by the Mayo Clinic, Rochester, Minn. However, says Anthony J. Windebank, MD, professor of neurology and one of the study investigators, with only 10 patients evaluated so far, initial findings have to be taken cautiously. Nor do they shed any light on the etiology of the syndrome. Windebank reported these preliminary results at the annual meeting of the American Academy of Physical Medicine and Rehabilitation in Washington, DC. <h3>Postpolio Problems</h3> The Mayo Clinic study was started by Mary B. Codd, MD, in response to widespread interest in the physical difficulties
MS Prevalence— Genes vs Geography
Authors: Chris Anne Raymond
Journal: JAMA (1986)

OPEN ANY medical textbook, and it will tell you that multiple sclerosis prevalence varies with latitude: the further away from the equator, the greater one's risk of contracting it. This north-south gradient, noted in dozens of epidemiologic studies dating from the 1920s, traditionally has been thought to be due to some environmental factor more common in temperate climates. One investigator, using much of the same epidemiologic evidence, is questioning this dogma. He argues that the north-south gradient "at least in part, reflects ethnic migration and genetic susceptibility," rather than indicating the existence of an environmental trigger unique to northern climates. George C. Ebers, MD, is associate professor, Department of Clinical Neurological Sciences, University of Western Ontario, London. At the American Academy of Neurology meetings in New Orleans, he and co-investigator Dennis Bulman, a graduate student, presented results of an analysis of data from census surveys and studies of veterans conducted
Successful treatment of a patient with octreotide-resistant necrolytic migratory erythema
Authors: A.P. BEWLEY, J.S. ROSS, C.B. BUNKER, R.C.D. STAUGHTON
Journal: British Journal of Dermatology (1996)

We report a patient with the glucagonorna syndrome and octreotide‐resistant necrolytic migratory erythema (NME). The NME responded on two occasions to an intravenous infusion of essential fatty acids (EFA) and ammo acids (AA). A deficit of serum EFA prior to treatment was corrected following the infusion, whilst plasma AA were low before and after treatment. These findings indicate that NME, in the glucagonoma syndrome, may respond to correction of the EFA deficit, and that NME‐may be a disease of EFA deficiency.
Endoscopy International Open – recently published
Journal: Endoscopy (2014)

See also: Effect of novel bright image enhanced endoscopy using blue laser imaging (BLI)Endosc Int Open 2014; 02(04): E212-E219DOI: 10.1055/s-0034-1390707 See also: A pilot study of the endomicroscopic assessment of tumor extension in Barrett’s esophagus–associated neoplasia before endoscopic resectionEndosc Int Open 2015; 03(01): E19-E28DOI: 10.1055/s-0034-1377935 See also: In situ cooling with ice water for the easier removal of self-expanding nitinol stents Endosc Int Open 2015; 03(01): E51-E55DOI: 10.1055/s-0034-1390760
A SCIENTIFIC BACKGROUND FOR THE USE OF ARSENICAL AND MERCURIAL COMPOUNDS IN SYPHILIS
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Endoscopy International Open – recently published
Journal: Endoscopy (2016)

See also: A comparative study of grasping-type scissors forceps and insulated-tip knife for endoscopic submucosal dissection of early gastric cancer: a randomized controlled trialEndosc Int Open 2016; 04(06): E654-E660DOI: 10.1055/s-0042-105870 See also: Optical diagnosis of malignant colorectal polyps: is it feasible?Endosc Int Open 2016; 04(07): E778-E783DOI: 10.1055/s-0042-107667 See also: Temporary duodenal stenting as a bridge to ERCP for inaccessible papilla due to duodenal obstruction: a retrospective studyEndosc Int Open 2016; 04(09): E957-E963DOI: 10.1055/s-0042-107070
A Novel Approach to Anxiolytic Premedication for Day-Case Patients
Authors: J W Mackenzie
Journal: Journal of the Royal Society of Medicine (1991)

The usefulness of 10 mg timolol orally as a non-sedative anxiolytic premedicant for day-case patients was examined in a double-blind placebo-controlled study. Patients were invited to take part by letter sent the week before gynaecological (n = 40) or oral (n = 60) surgery was scheduled. Indices of anxiety and alertness were obtained prior to administration of the tablet; quality of previous anaesthetic experience was also recorded. In those patients with no previous or unpleasant previous anaesthetic experience a significant reduction in anxiety amongst those given timolol was identified. Haemodynamic differences between the groups were not clinically significant, and return of psychomotor function was not delayed by timolol. Timolol effectively reduces situational anxiety, is non-sedative, and is advocated as a premedicant for anxious day-case patients and others in whom rapid return of psychomotor function is desirable.