Cocaine-Related Vasculitis Causing Upper-Limb Peripheral Vascular Disease
Authors: P. Dileep Kumar, Howard R. Smith
Journal: Annals of Internal Medicine (2001)

Letters6 November 2001Cocaine-Related Vasculitis Causing Upper-Limb Peripheral Vascular DiseaseP. Dileep Kumar, MD and Howard R. Smith, MDP. Dileep Kumar, MDHuron Hospital, Cleveland Clinic Health System; Cleveland, OH 44112 (Kumar, Smith)Search for more papers by this author and Howard R. Smith, MDHuron Hospital, Cleveland Clinic Health System; Cleveland, OH 44112 (Kumar, Smith)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-9-200111060-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Our patient had no history of chronic repetitive trauma to the hands from any occupations or hobbies. Although a hypercoagulable state is unlikely to cause vasculitis, the patient had normal levels of homocystine and antithrombin III. During one of his previous admissions, lupus anticoagulant and factor V Leiden were not detected and both protein C and protein S levels were low because of warfarin therapy.The purpose of our report was to highlight the role of cocaine in causing arterial diseases. Although vasculitis is an attractive explanation, the exact causal mechanism is unknown. The literature is sparse and ...References1. Brust JC. Vasculitis owing to substance abuse. Neurol Clin. 1997;15:945-57. [PMID: 9367974] CrossrefMedlineGoogle Scholar2. Krendel DA, Ditter SM, Frankel MR, Ross WK. Biopsy-proven cerebral vasculitis associated with cocaine abuse. Neurology. 1990;40:1092-4. [PMID: 2356010] CrossrefMedlineGoogle Scholar3. Shionoya S. Diagnostic criteria of Buerger's disease. Int J Cardiol. 1998; (66 Suppl 1):S243-5; discussion S247. [PMID: 9951826] Google Scholar4. Marder VJ, Mellinghoff IK. Cocaine and Buerger disease: is there a pathogenetic association? Arch Intern Med. 2000;160:2057-60. [PMID: 10888980] CrossrefMedlineGoogle Scholar5. Lisse JR, Davis CP, Thurmond-Anderle M. Cocaine abuse and deep venous thrombosis [Letter]. Ann Intern Med. 1989;110:571-2. [PMID: 2923390] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Huron Hospital, Cleveland Clinic Health System; Cleveland, OH 44112 (Kumar, Smith) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCocaine-Related Vasculitis Causing Upper-Limb Peripheral Vascular Disease P. Dileep Kumar and Howard R. Smith Cocaine-Related Vasculitis Causing Upper-Limb Peripheral Vascular Disease John A. Spittell Jr. and Peter C. Spittell Metrics Cited ByCocaine-related peripheral vascular occlusive disease treated with iloprost in addition to anticoagulants and antibioticsHipertensión arterial sospechosa 6 November 2001Volume 135, Issue 9Page: 843KeywordsCocaineFactor V LeidenHypertensionMedical risk factorsPathogensPeripheral vascular diseaseProteinsThrombosisVascular diseasesVasculitis ePublished: 6 November 2001 Issue Published: 6 November 2001 CopyrightCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...