tbuckley/cabot-search huggingface dataset:
Smallpox vaccination
Authors: J. M. Lane
Journal: JAMA (1977)

OLD IDEAS die hard. For more than a century and a half, the medical and public health professions have Vigorously promoted smallpox vaccination. "Antivaccinator" became synonymous with anti-intellectual. Patients ask us, "I was vaccinated, my children were vaccinated, all my family have been vaccinated; why aren't you vaccinating my grandchildren?" We have dropped smallpox vaccination just when the media have been criticizing the medical profession for lack of attention to preventive medicine. Some patients, and indeed some of our medical colleagues, do not understand the rationale behind cessation of routine smallpox vaccination. <b>Where does smallpox come from?</b>While most patients understand the concept of infection or contagiousness, they frequently have not thought in terms of the source or reservoir of infectious agents. Although smallpox virus can be found for a short time in scabs and bedding from patients, for practical purposes infection results only from contact with patients in the
Carcinoembryonic antigen assay in hepatic metastases detection. An adjunct to liver scanning
Authors: W. H. McCartney
Journal: JAMA (1976)

In a double-blind study involving 377 patients, we assessed the value of the serum carcinoembryonic antigen (CEA) assay as an adjunct to the radio-nuclide liver scan for detection of liver metastases. Fifty-seven patients studied by both methods were ultimately proved to have liver metastases. In 28 instances in which the results of both tests were in agreement, these results were diagnostic with regard to presence or absence of hepatic involvement. The CEA assay suggested the presence of metastatic tumor in eight of the 12 patients with false-negative liver scans, thus proving to be a very useful adjunct to liver scanning in the detection of hepatic metastasis. (<i>JAMA</i>236:1023-1027, 1976)
Military medicine faces at least 4 more months of supporting US, other peacekeepers in Somalia
Authors: P. Gunby
Journal: JAMA (1993)

THIS YEAR'S meeting of the Association of Military Surgeons of the United States (AMSUS)—which ended just over a week ago—was held in San Antonio, Tex. But the thoughts of many of those present, whether active ser-vice personnel, reservists, or retirees, were on Somalia, where US military medicine continues to cope with appalling and often dangerous conditions. In addition to combat wounds, other injuries, and disease among US personnel, the US Army's 46th Combat Support Hospital/Medical Task Force 46 in the Somali capital of Mogadishu also provides some medical support for some of the other nations' United Nations (UN) peacekeeping troops and treats Somali civilians when circumstances dictate and permit. Although there are a great many sources of disease in Somalia, US military medical people have encountered just one case of HIV infection among the patients seen to date. That was a Somali who underwent testing before US military physicians performed
Do breast cancer treatment and imaging providers follow hereditary breast and ovarian cancer risk screening guidelines?
Authors: Katherine Y. Tossas-Milligan, Anne Marie Murphy, Christine B. Weldon, Julia Rachel Trosman, Melissa A. Simon, Betty Roggenkamp, William J. Gradishar
Journal: Journal of Clinical Oncology (2014)

207 Background: Women with personal or family history suggestive of susceptibility to hereditary breast or ovarian cancer (HBOC) should be referred to genetic assessment (USPSTF, Ann Intern Med. 2005). Women with HBOC have a 50-85% lifetime risk of breast cancer, 30-50% of breast cancer before 50 years old,15-50% lifetime risk of ovarian cancer, and 40-60% chance of developing a second breast cancer (ASCO Cancer.net HBOC 8/2013). Our goal is to examine if this almost decade old guideline is followed in breast cancer treatment and breast cancer imaging centers in a large metropolitan area. Methods: We conducted an IRB approved web survey of all 35 breast cancer treatment sites (5 academic, 21 community, 9 public or safety net) and 58 breast imaging sites (5 academic, 27 community, 26 public or safety net) in Chicago. Results were analyzed using simple frequencies and Fisher's exact test. Results: We achieved a response rate of 91% (32/35 treatment sites, 53/58 imaging sites). We found that 56% (18/32) of treatment sites have a hereditary cancer syndrome (HBOC) screening process for newly diagnosed breast cancer patients. Most of these sites, 83% (15/18), always use genetic test results in surgical decisions, as compared to 21% (3/14) of sites that do not have an HBOC screening process, p=0.0009. Only 8% (4/53) of breast imaging sites have an HBOC screening process and provide indicated patients genetic assessment information and/or referrals. While 38% (20/53) of imaging sites conduct daily internal staff discussions of hereditary risk, only 15% of them (3/20) provide genetic assessment information to indicated patients. We found no statistically significant difference between practices of academic, community, public and safety net sites. Conclusions: Breast cancer treatment sites have partial adherence to HBOC risk screening guidelines; while breast imaging sites rarely adhere to HBOC risk assessment guidelines. Consistent HBOC risk screening protocols are needed in breast cancer treatment and breast cancer imaging sites that include providing indicated patients information about, and access to, genetic assessment.
Post-transplant lymphoproliferative disease after adult liver transplantation has a higher incidence after primary sclerosing cholangitis and can be prevented by surveillance of Epstein-Barr viral load with a pre-emptive strategy - a long-term study
Authors: Mitchell Hew, Bastian Ruijter, Naftalie Francisco, Herold J. Metselaar, Ron Wolterbeek, Jeroen Dubbeld, Ann C.T.M. Vossen, Bart Van Hoek
Journal: Journal of Hepatology (2020)
Missing Lines
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Osteolysis of the mandible and maxilla
Authors: E. C. Cabal
Journal: JAMA (1978)

<h3>History</h3> A 30-year-old man had a history of intermittent pain for the past four years in the area of previous molar teeth extractions. An oroantral fistula subsequently developed, and he began losing teeth from his mandible. He had periods of remissions and exacerbations concurrent with various treatment procedures during the next three years. There was no history of metabolic disease or exposure to radiation. Roentgenograms of the mandible are shown in Fig 1. Skeletal survey did not disclose any other bone abnormality. <h3>Diagnosis</h3> Osteolysis of the mandible and maxilla secondary to chronic actinomycosis infection. <h3>Comment</h3> Figure 1 shows extensive osteolysis and thinning of the mandible, with pathological fracture of the body of the right side. Maxillary osteolysis is also present, but of lesser degree. Actinomycetes are normal flora of the mouth, but at times may be the cause of infection. There are three species implicated in human infection:<i>Actinomyces</i>
University of Prague
Authors: Rolf Oestreicher
Journal: JAMA (1965)

<h3>To the Editor:—</h3> The only possible connection of Prague University and the word "German" might conceivably be the fact that Prague, the capital of Bohemia, was, at that time, in the territory of the Holy Roman Empire. Charles I, king of Bohemia, became German Emperor only seven years after he had founded the Prague University.
RAS Pathway Mutations Are Highly Prevalent In Relapsed Childhood Acute Lymphoblastic Leukaemia, Are Frequently Relapse-Drivers and Confer Sensitivity To MEK Inhibition
Authors: Julie Irving, Elizabeth C. Matheson, Lynne Minto, Helen Blair, Marian Case, Christina Halsey, Isabella Swidenbank, Frida Ponthan, Renate Kirschner-Schwabe, Stefanie Groeneveld-Krentz, Jana Hof, James Allan, Christine J. Harrison, Josef Vormoor, Arend Stackelberg, Cornelia Eckert
Journal: Blood (2013)
Epidemiology of women with AIDS in the United States, 1981 through 1990. A comparison with heterosexual men with AIDS
Authors: T. V. Ellerbrock
Journal: JAMA (1991)

In the United States, women account for an increasing number and percentage of adults with the acquired immunodeficiency syndrome (AIDS). Overall, 51% of women with AIDS were infected through intravenous drug use and 29% through heterosexual contact; the proportion of intravenous drug users decreased, while the proportion attributed to heterosexual contact increased, between 1986 and 1990. Most women with AIDS were black or Hispanic (72%); residents of large metropolitan areas (73%), especially cities along the Atlantic coast; and of reproductive age (15 to 44 years) (85%). However, the proportion of women with AIDS reported by smaller cities and rural areas has increased from 22% in 1986 to 28% in 1990. The male-to-female ratio of heterosexuals with AIDS has remained about 2.4:1 since 1987. A comparison of women with AIDS to heterosexual men with AIDS showed that these two groups were similar by age, race, and geographic distribution. Also, survival times from AIDS diagnosis to death for women and heterosexual men with AIDS were not significantly different. (<i>JAMA</i>. 1991;265:2971-2975)
The Oncologist
Authors: Derek Raghavan
Journal: JAMA (1997)

The first few issues of a new journal are always interesting for what they reveal about the growth of research and practice in the health sciences.<i>The Oncologist</i>produces original papers, reviews, and commentaries that address the multimodality diagnosis and treatment of cancer. This new journal has been designed specifically for the "busy practicing oncologist and hematologist entrusted with caring for cancer patients." The pedigree of the editorial board also offers important clues as to how well a new journal will prosper and achieve its mission. As its subtitle indicates,<i>The Oncologist</i>aspires to be "the international peer-reviewed journal for the practicing oncologist/hematologist." Its founding editors, Drs Bruce Chabner, Gregory Curt, and H. M. Pinedo come from the Massachusetts General Hospital (Boston), the National Cancer Institute (Washington, DC), and the Free University Hospital in Amsterdam, the Netherlands. The executive editor, Martin Murphy, Jr, practices at the Hipple Cancer Research Center in
IgM gammopathy and the lupus anticoagulant syndrome in habitual aborters
Authors: N. Gleicher
Journal: JAMA (1985)

Recent reports strongly suggest an association between a laboratory picture of autoimmunity in the absence of clinical signs and symptoms and the recurrence of spontaneous pregnancy loss. This association seems particularly strong when circulating lupus anticoagulant is present and has therefore been called the<i>circulating lupus anticoagulant syndrome</i>. We present four patients with this syndrome who in addition to the asymptomatic autoimmune laboratory picture were also found to exhibit a distinct IgM gammopathy. In view of earlier reports that implicated IgM in poor pregnancy outcome, particularly in association with systemic lupus erythematosus, it is suggested that all patients with circulating lupus anticoagulant syndrome be evaluated for an IgM gammopathy. A fraction of IgM may be detrimental to development and growth of the normal fetal placental unit and may thus be implicated in repeated early pregnancy loss. (<i>JAMA</i>1985;253:3278-3281)
FOREIGN OBJECTS IN THE CIRCULATION
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pitfalls in Measuring Cytokines
Authors: Larry C. Case
Journal: Annals of Internal Medicine (1994)

Letters15 July 1994Pitfalls in Measuring CytokinesLarry C. Case, MD, PhD, Robert Balk, MD, and Roger Bone, MDLarry C. Case, MD, PhD, Robert Balk, MD, and Roger Bone, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-121-2-199407150-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Numerous assays are available to investigators for measuring cytokines, and a study by Parson and colleagues [1] shows that different assays yield different results. Which is correct? Why are there differences? The data from Dr. Mann and colleagues show that the presence of circulating soluble receptors to TNF may interfere with TNF immunoassays, depending on the assay kit. In the data presented, 500 ng/mL of the circulating soluble receptors resulted in the loss of detection of TNF by using the assay kit we used. However, the concentration of these receptors in their study was approximately 50 times higher ...REFERENCE1. Parsons PE, Moore FA, Moore EE, Ikle DN, Henson PM, Worthen GS. Studies on the role of tumor necrosis factor in adult respiratory distress syndrome. Am Rev Respir Dis. 1992; 146:694-700. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPlasma Cytokine Parameters and Mortality in Patients With Chronic Heart FailureTumor Necrosis Factor-α and Tumor Necrosis Factor Receptors in the Failing Human HeartTumor necrosis factor-α and the failing human heart-TNFα and heart failure 15 July 1994Volume 121, Issue 2Page: 149-150KeywordsAttentionBioassays and physiological analysisCellsCytokinesImmunoassaysMortalitySepsisT cell receptorsT cellsTumor necrosis factor Issue Published: 15 July 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Exfoliative Cytopathology
Authors: Tilde S. Kline
Journal: JAMA (1977)

It is a pleasure to explore the second edition of Naib's<i>Exfoliative Cytopathology</i>, now expanded from 398 to 531 pages. This authoritative volume, as in the first edition, correlates disease processes with exfoliated cells from sources throughout the body. Included are detailed descriptions of cellular morphology as well as noteworthy diagnostic pitfalls. A new feature is a unique chapter on dermatocytopathology. Here Naib demonstrates cells from infectious diseases and nonspecific inflammation as well as malignant neoplasms. Additional sections include synovial effusions and the cytology of the eye. Praiseworthy, too, is the expansion and emphasis throughout of bacterial and fungal infections as well as cell alterations secondary to viral disease. In three areas the text might have been amplified. First, despite Naib's statement in the first edition that there is no exhaustive review of the literature, the second edition is even less comprehensive, with only limited references beyond 1970. Second, there
Transposed Figures
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Results of A Phase I Study of Milatuzumab, a Humanized Anti-CD74 Antibody, and Veltuzumab, a Humanized Anti-CD20 Antibody, In Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma,
Authors: Beth Christian, Lapo Alinari, Jeffrey A. Jones, Don M Benson, Joseph M. Flynn, Pierluigi Porcu, Mark E Lustberg, Mitchell Phelps, Ming Poi, Diana Chung, Carl Quinion, John C. Byrd, William Wegener, David M Goldenberg, Robert A. Baiocchi, Kristie A. Blum
Journal: Blood (2011)
Advances in antiarrhythmic therapy. The role of newer antiarrhythmic drugs
Authors: K. Nademanee
Journal: JAMA (1982)

THE APPROACH to the management of disorders of cardiac rhythm has undergone major changes in the last ten years.<sup>1,2</sup>The early experience with surgery and with pacemakers suggests that these modes of therapy hold much promise; however, it is unlikely that they will have a major appeal for the largest numbers of patients needing antiarrhythmic therapy.<sup>1</sup>Drug therapy is therefore likely to remain the mainstay of long-term antiarrhythmic treatment for both supraventricular as well as ventricular tachyarrhythmias. Clinicians have long sought the "ideal" antiarrhythmic agent, one that has a wide spectrum of therapeutic efficacy, is potent, well tolerated by the patient while having little or no side effects, but with pharmacokinetics appropriate for long-term prophylaxis. Although the discovery of such a compound still appears elusive, many new drugs are now being evaluated in the United States.<sup>3,4</sup>Their investigational use is growing, and some are likely to be approved
Tommy
Authors: Abigail Zuger
Journal: JAMA (1987)

I'm almost sure he's dead by now; the last time I talked to the people in New York, he had sent his family away and was refusing to eat or open his eyes. He wasn't particularly unique: a skinny little drug addict with a long prison record and a fast mouth, who hadn't managed to turn his life around in time. He was, in fact, more or less indistinguishable from all the other patients in our Friday morning AIDS clinic. But we all agreed that Tommy had a certain style. His AIDS was diagnosed about two years ago. When he appeared in my examining room for the first time a month later, I learned that he was married and no longer used drugs. On his second visit he mentioned that his wife was four months pregnant. On his third visit he confided that she was also mentally retarded. Sandra couldn't
Microaeration Technique for Measurement of the Two Components of the Blood Ammonia Level
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Errors in Table 2
Authors: Cari Kitahara, Amy Berrington De González, Dale Dphil
Journal: JAMA Internal Medicine (2019)

Ian M. Kronish, MD, MPH; Nathalie Moise, MD, MS; Ying Kuen Cheung, PhD; Gregory N. Clarke, PhD; Rowena J. Dolor, MD, MHS; Joan Duer-Hefele, RN; Karen L. Margolis, MD, MPH; Tara St Onge, RN; Faith Parsons, MS; Jessica Retuerto, BA; Anusorn Thanataveerat, MPH; Karina W. Davidson, PhD, MASc
Block Grants
Authors: F. Ross Woolley
Journal: JAMA (1982)

PASSAGE of the Omnibus Reconciliation Act (OBRA) of 1981 may have the most far-reaching impact on health care provision and consumption in this country of any legislation since the Medicare and Medicaid amendments to the Social Security Act. Intending to transfer federal funds directly to states for distribution and control, the OBRA included nine block grants, four of which relate directly to the provision of health care. These grants consolidate 22 existing programs and provide for at least a 25% reduction in program funding. The general areas for these new block grants include (1) maternal and child health; (2) alcohol and drug abuse and mental health; (3) primary care, which includes The Community Health Services program; and (4) preventive health and health services. The potential impact of block grants is directly proportional to the extent to which the federal government has influenced both the supply and demand for health care
StatBite Proportion of Specific Cancers Caused by HPV
Journal: JNCI Journal of the National Cancer Institute (2010)

About 30 to 40 types of human papillomavirus (HPV) infect the genital tract.High-risk types of HPV, such as HPV16, 18, 31, and 45, are associated with anogenital cancers.While HPV causes virtually all cervical cancers, it causes about 90% of anal cancers, about half of vulvar, vaginal, and penile cancers, and about 12% of oropharyngeal cancers, which occur in the oral cavity and throat.HPV vaccines were initially approved for girls, but they may be given to boys and their use is being considered for other groups as well, such as older women (see news story, p. 838).