tbuckley/cabot-search huggingface dataset:
Proceedings of the American Diabetes Association, First Annual Meeting, Cleveland, Ohio, June I, 1941
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Resident Burnout
Authors: Troy Madsen
Journal: Annals of Internal Medicine (2002)

Letters15 October 2002Resident BurnoutTroy Madsen, BATroy Madsen, BAJohns Hopkins University School of Medicine; Baltimore, MD 21210Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-8-200210150-00022 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:As Shanafelt and colleagues revealed (1), resident burnout is prevalent. Residents face long hours, sleepless nights, and heavy workloads, and they often find themselves frustrated with patient care responsibilities. The effects of this burnout, though, are not confined to a resident's personal life or attitude. As a third-year medical student rotating through clinical clerkships, I have found that the burnout inherent in residency extends beyond the residents' lives and into the sphere of medical education.The chief resident of my gynecology rotation described the process succinctly. “As an intern, you spend your entire year lost,” she explained. ...Reference1. Shanafelt TD, Bradley KA, Wipf JE, Back AL. Burnout and self-reported patient care in an internal medicine residency program. Ann Intern Med. 2002;136:358-67. [PMID: 11874308] LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Johns Hopkins University School of Medicine; Baltimore, MD 21210 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBurnout and Self-Reported Patient Care in an Internal Medicine Residency Program Tait D. Shanafelt , Katharine A. Bradley , Joyce E. Wipf , and Anthony L. Back Resident Burnout Anthony L. Back , Joyce E. Wipf , and Tait D. Shanafelt Resident Burnout Ira S. Nash Resident Burnout W. Robert Graham Metrics Cited BySentimentos do Estudante de Medicina quando em Contato com a PráticaEstresse na Formação Médica: como Lidar com Essa Realidade?Medical Student Distress: Causes, Consequences, and Proposed Solutions 15 October 2002Volume 137, Issue 8Page: 700KeywordsMedical educationPatientsResidencyToxicity ePublished: 15 October 2002 Issue Published: 15 October 2002 CopyrightCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Resistance rising
Authors: Laurie Goodman
Journal: Journal of Clinical Investigation (2004)

Resistance risingThe rise in the number and percentage of community-acquired Staphylococcus aureus infections that are methicillin resistant was highlighted at the 42nd annual meeting of the Infectious Diseases Society of America held in Boston in September 2004 (http:// www.idsociety.org).Methicillin-resistant S. aureus (MRSA) infections are more commonly found in individuals who are or have been in a hospital or health care facility, but findings reported in more than 25 poster presentations showed a significant increase in MRSA infections in healthy individuals who have none of the usual risk factors.Kevin Purcell, a health care consultant for Driscoll Children's Hospital in Corpus Christi, Texas, and presenter of one of the posters, told the JCI, "The rate of methicillin resistance in our Staph.aureus isolates slowly increased from 3% in 1990 to 10% in 1999 and then rapidly increased over a 4-year period to 62% in 2003."Also worth noting is that the types of infections being caused by this community-acquired MRSA (CA-MRSA) can vary significantly from population to population.Most presentations showed that CA-MRSA infections occur primarily in the skin or soft tissue, but there was also a rise in the number of cases of CA-MRSA pneumonia, and Loren Miller and colleagues recorded in Los Angeles 14 CA-MRSA cases of necrotizing fasciitis, better-known to the public as flesh-eating bacteria.These infections are particularly unusual because necrotizing fasciitis is usually caused by group A Streptococcus, not by S. aureus.In Purcell's study, 94% of the infections were localized to the skin."We had a much smaller percentage of invasive infections and only 1 case of the necrotizing fasciitis," Purcell said."Our greatest concern was that the skin infections were becoming more and more common.Furthermore, the community-acquired MRSA strains have more of an ability to cause these kinds of infections than the non-MRSA strains."Purcell believes that the data from his and the other studies suggest a real need to think carefully about how antibiotics are used now as compared to a few years ago.CA-MRSA can be treated with several currently used antibiotics but is resistant to first-generation cephalosporins, which, not long ago, were the front-line antibiotics.Most doctors now generally use clindamyo-
Gonorrhea—United States, 1998
Journal: JAMA (2000)

Neisseria gonorrhoeae infections are a major cause of pelvic inflammatory disease, infertility, and ectopic pregnancy in women and facilitate the transmission of human immunodeficiency virus (1). To characterize the epidemiology of gonorrhea in the United States, CDC examined national surveillance data on gonorrhea cases reported to CDC through state health departments in 1998 and surveyed selected states with increases and decreases in gonorrhea rates since 1996. This report summarizes the results of this analysis, which indicate that following a 13-year decline, the number of gonorrhea cases in 1998 increased by 9% compared with 1997. Although changes in gonorrhea screening and surveillance practices may have contributed to the higher reported rates, reports from states suggest that true increases in gonorrhea cases also occurred in some populations.
Oncological Nursing Sessions
Authors: Franca Manzin, G Fabbrokt, L Foghin', C Raiti, P Stlli, M Todisco, V De Pangher Manzini, Oncologia Di, Oncologia Ospedau, Dl Gor121a, E Monfalcone, " Isonttna" 'medico, Tnfermiera Ps1cologa, Francolettj Michela, Nadia Rossana Berardl, Riccardo Cappanera, Franca Cellerino, Clinica Puuta, D Ancona, Serenefta Gfni, Sotua Barb, Maunzw Canepa, Serpo Rjcci, Dip Oncotogb, Osn Ouara, Enmokrgax Oxp, S Martmo
Journal: Annals of Oncology (2001)
Lactate dehydrogenase (LDH) levels predict benefit from the continuation of bevacizumab (bev) beyond progression in metastatic colorectal cancer (mCRC): subgroup analysis of the randomized BEBYP study
Authors: F. Marmorino, C. Cremolini, F. Loupakis, L. Salvatore, G. Masi, C. Barbara, F. Dargenio, E. Miraglio, L. Ginocchi, L. Antonuzzo, R. Moretto, M. Schirripa, S. Chiara, C. Banzi, D. Amoroso, A. Bonetti, A. Martignetti, M. Paris, L. Boni, D. Tomcikova, A. Falcone
Journal: Annals of Oncology (2016)
Basic Surgery
Authors: W. G. Abel
Journal: JAMA (1987)

This 656-page paperback second edition is an updated version of the original 1977 publication. As stated by the editors, it is "prepared as a textbook and supplement for the medical student and surgical resident." For ease of reference the book has been divided into four units and comprises 35 chapters. Unit 1 discusses "Basic Considerations" and covers metabolic responses, monitoring, fluid and electrolyte balance, immune responses, tissue healing, surgical infections, and cancer. The presentations are abbreviated, but for the audience intended it serves very well. The chapters on monitoring and immune response are particularly well done. Unit 2, covering "Total Care," contains basic information and allows the student to become familiar with new terms and concepts. Units 3 and 4, on "Principles of General Surgery" and "Principles of Speciality Surgery," provide a general discussion of the various body systems, emphasizing the principles of therapy rather than detailing surgical technique. The
Communications Skills Training for Health Care Providers and Patient Satisfaction
Journal: Annals of Internal Medicine (1999)

Summaries for Patients7 December 1999Communications Skills Training for Health Care Providers and Patient SatisfactionSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-11-199912070-00026 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Many health care organizations are investing resources in communication skills training for their staff. Little is known, however, about whether this type of training actually improves patients' satisfaction with their health care.Why did the researchers do this particular study?The researchers wanted to find out whether patients being cared for by providers who had completed a special course in communication skills were more satisfied with their health care than patients whose providers did not have this special training.Who was studied?The study included 52 doctors and ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Effect of Clinician Communication Skills Training on Patient Satisfaction. A Randomized, Controlled Trial.” It is in the 7 December 1999 issue of Annals of Internal Medicine (volume 131, pages 822-829). The authors are J.B. Brown, M. Boles, J.P. Mullooly, and W. Levinson.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffect of Clinician Communication Skills Training on Patient Satisfaction Jonathan Betz Brown , Myde Boles , John P. Mullooly , and Wendy Levinson Metrics 7 December 1999Volume 131, Issue 11Page: 822KeywordsCommunication in health careHealth careHealth care providersHealth maintenance organizationsNursesPatientsPhysicians ePublished: 15 August 2000 Issue Published: 7 December 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.Loading ...
Tubercle Formation
Authors: Adolph Rostenberg
Journal: British Journal of Dermatology (1963)

Journal Article Tubercle Formation Get access Adolph Rostenberg, Jr. Adolph Rostenberg, Jr. Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 75, Issue 11, 1 November 1963, Pages 449–450, https://doi.org/10.1111/j.1365-2133.1963.tb13542.x Published: 01 November 1963
SAMIT: A phase III randomized clinical trial of adjuvant paclitaxel followed by oral fluorinated pyrimidines for locally advanced gastric cancer.
Authors: Kazuhiro Yoshida, Akira Tsuburaya, Michiya Kobayashi, Shigefumi Yoshino, Masazumi Takahashi, Nobuhiro Takiguchi, Kazuaki Tanabe, Naoto Takahashi, Hiroshi Imamura, Naokuni Tatsumoto, Akinori Hara, Kazuhiro Nishikawa, Ryoji Fukushima, Akira Kurita, Hiroshi Kojima, Yumi Miyashita, Koji Oba, Marc E. Buyse, Satoshi Morita, Junichi Sakamoto
Journal: Journal of Clinical Oncology (2013)

LBA4002 Background: Adjuvant chemotherapy with tegafur/uracil (UFT) used to be a tentative Japanese standard treatment and has been replaced by S-1 according to the result of the ACTS-GC trial, although there has been no direct comparison. Paclitaxel (PTX) has been widely used as one of the key drugs for unresectable GC. A randomized phase III trial with a two-by-two factorial design was planned to assess the survival benefit of sequential use of PTX and oral fluorinated pyrimidines (FPs) in comparison with FPs alone, and to compare UFT and S-1. Methods: Patients with serosa-invading GC who underwent R0/1 resection with extended (D2) lymph node dissection were randomized to receive either UFT 267mg/m 2 daily (arm A), S-1 80mg/m 2 daily for 2 weeks every 3 weeks (B), weekly PTX 80 mg/m 2 followed by UFT (C), or PTX followed by S-1 (D) for 24 weeks. The primary endpoint was disease-free survival (DFS). 708 patients per groups were necessary to detect a hazard ratio of 0.8 with 90% power for superiority of the sequential arms, C+D, vs. A+B (two-sided 5.0% significance level). The number of patients was set to 370 per arm (total 1480) with an 88% power for noninferiority (1.33 as the margin) of UFT vs. S-1. Results: Between August 2004 and October 2007, 1,495 patients from 232 centers were randomized with the full analysis set of 1,433. Demographics were well balanced among arm A (n=359), B (n=364), C (n=355), and D (n=355); mean age was 64, 86% were PS 0, 68% of tumors were 8 cm or greater and 85% were clinically node positive. Grade 3-4 neutropenia or anorexia occurred in 11% or 6%, 13% or 7%, 13% or 2%, and 23% or 5% for arm A, B, C, and D, respectively. Other % grade 3-4 toxicities were less than 5%. Median follow-up was 1,875 days and 728 events occurred. Difference in DFS between C+D and A+B were not statistically significant (HR=0.92, 95%CI 0.80-1.07, p= 0.273). HR of A+C vs. B+D was 1.23 (95%CI 1.07-1.43) and hence the null hypothesis was not rejected. Conclusions: There was a trend for better DFS for sequential use of PTX followed by FPs. Comparison between the FPs demonstrated that UFT was inferior to S-1. Sequential PTX/S-1 is safe and effective for locally advanced GC in an adjuvant setting. Clinical trial information: C000000082.
Sedimentation Rate
Authors: Ian Wicks
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Biliary tumor thrombus of hepatocellular carcinoma containing lipiodol mimicking a calcified bile duct stone
Authors: T. Sasaki, N. Takahara, Y. Kawaguchi, H. Takao, K. Matsusaka, K. Miyabayashi, N. Yamamoto, K. Hirano, H. Isayama, J. Kaneko, N. Kokudo, K. Koike
Journal: Endoscopy (2012)

Correction to: Biliary tumor thrombus of hepatocellular carcinoma containing lipiodol mimicking a calcified bile duct stoneEndoscopy 2012; 44(S 02): E250-E251DOI: 10.1055/s-0032-1309761
JOHN JONES (1729-1791) PHYSICIAN TO WASHINGTON AND FRANKLIN
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Psychiatry
Authors: D. X. Freedman
Journal: JAMA (1979)

Pharmacotherapies that are at least partially specific and research that delineates diagnostic subgroups instill a new purpose into careful diagnosis and treatment monitoring. Today's psychiatrist must not only perfect psychotherapeutic skills, but also must exercise vigilance in differential diagnosis and be able to use not one or two but several therapies. <h3>Diagnostic Precision</h3> From the mid-1930s to its peak in the mid-1950s, the trend in American psychiatry, except for a few centers, was to overlook the diagnosis of manic-depressive disease and to overdiagnose schizophrenia; the diagnosis of schizophrenia was made eightfold more here than in Great Britain.<sup>1</sup>Historical, cross-national, and contemporary research predict that admissions for rigorously and reliably diagnosed schizophrenia and affective disorders should be close to a 1:1 ratio. Even now there may be 100,000 people classified as chronic schizophrenics who, with systematic and rigorous rediagnosis, would be reclassified as having affective disorders. Perhaps an overdiagnosis of
Piloting when you 'should' be sleeping: what effects?
Authors: P. Gunby
Journal: JAMA (1981)

Researchers call it "circadian desynchronosis," the public calls it "jet lag," and the National Aeronautics and Space Administration (NASA) calls it a potential health hazard for anyone aboard an airliner flown by a pilot who probably should be sleeping. To "determine how irregular work schedules, disrupted sleep patterns, and frequent crossing of time zones affect airline pilot performance," NASA's Ames Research Center near San Francisco is conducting a four-part study. As a first step, the scientific literature on circadian physiology is being reviewed. This information will be summarized in nontechnical terms for the aviation community. Second, a study of rest, diet, and medication use patterns of commercial airline crews will be undertaken. Third, Ames' facility for prolonged bed rest (to simulate astronauts' weightlessness) will be used to study altered sleep and nutrition patterns. Fourth, facilities under construction (including simulated airplane cockpits) will allow volunteer airline crews to "fly" for several
Intensive care medicine/nutrition
Authors: E Tankurt, ~ Apaydin, H Guven, E Ellidokuz, D Gamli, A Chiaravalli, M Cornaggia, M Salvadore, N Sonzini
Journal: Gut (1994)

3rd UEGWOslo 1994 and without sodium solution) it has been shown that intracellular alkalisation causes activation of electric contractive activity of smooth muscle of IAS and depression of rectal myocytes.Intracellular acidification is characterized by opposite changes of functional activity of smooth muscular formations.Replacement of bicarbonate in Kreb's solution on Trisaminometan or HEPES leads to depression of excitement processes and contraction of smooth muscle, which is partially removed by tetraethylammonium and addi- tion of bicarbonate in HEPES-contained solution.Removal of Cl-ions leads to opposite effect.Removal of anion exchange have exciting effect on myocytes of rectum and depressing effect on smooth muscle of IAS.These changes are connected with modulation of pofassiom and calcium permeability of my- ocytes membrane.It has been established, that together with system of Na+/H+-exchange ClV/HCO3-exchange plays an important role in support of pH regularity in cells of smooth muscles of anorectal region.
The efficacy of aprepitant for the patients receiving FOLFOXIRI and FOLFIRINOX: A phase II study.
Authors: Tetsuji Terazawa, Masahiro Goto, Takahiro Miyamoto, Ken Asaishi, Fukutaro Shimamoto, Shin Kuwakado, Hitoshi Nishitani, Takayuki Kii, Kazuhide Higuchi
Journal: Journal of Clinical Oncology (2016)

e21600 Background: Aprepitant (APR) showed the efficacy for the prevention of chemotherapy-induced nausea and vomiting (CINV) with highly emetogenic chemotherapy. The combination chemotherapies of moderately emetoegnic agents of oxaliplatin and irinotecan are classified as moderately emetogenic risk according to ASCO guideline, but showed severe vomiting and nausea. Methods: This phase II trial evaluated the efficacy of APR (dy1;125mg, day2-3; 80mg) in patients receiving mFOLFOXIRI(oxaliplatin; 85 mg/m2, irinotecan; 150 mg/m2, leucovorin; 200 mg/m2, 5-FU infusional; 2400 mg/m2, every 2 weeks) and FOLFIRINOX (L-OHP; 85 mg/m2, CPT-11; 180 mg/m2, LV;200 mg/m2, 5-FU bolus; 400 mg/m2, 5-FU infusional; 2400 mg/m2/46hour, every 2weeks). The primary objective was the complete vomiting inhibitation rate (CVIR) during first cycle. The null hypothesis and expectation of CVIR were 30% and 60% (one-sided α = 0.05, β = 1.0), so 23 patients were needed. CVIR was assessed according to MAT (MASCC Antiemesis Tool). Results: 25 patients were enrolled. The characteristics were as follows; median age (range), 65 (39-71); male/ female, 16/9; PS0/ 1, 11/ 14; mFOLFOXIRI/ FOLFIRINOX, 20/ 5; BMI < 22/ 22 or more, 14/ 11; history of alchol yes/ no, 11/ 14. The CVIR was 92% (95%CI: 74-99) and complete response (no vomiting and no rescue medication use) rate was 72% (95%CI: 51-88%). The toxicities (all grade/ grade 3 or 4) were as follows; nausea, 17/ 2; vomiting, 3/ 0; fatigue, 16/ 2; constipation, 6/ 0. Conclusions: APR was effective for CVIR. Further prevention of nausea is expected.