tbuckley/cabot-search huggingface dataset:
Interest of echocardiography in the management of acute kidney injury in cirrhotic patients with ascites. Results of the prospective pilot cirren study
Authors: Brahmia Sanaa, Wallon Grégoire, Dr Guichon Céline, Clothilde Miaglia, Domitille Poinsot, Pauline Devauchelle, Marianne Maynard, Mathieu Gazon, Serge Duperret, Frédéric Aubrun, Fabien Zoulim, Fanny Lebossé
Journal: Journal of Hepatology (2020)
THU0511 Update on the Juvenile Systemic Sclerosis Inception Cohort. www.juvenilescleroderma.com
Authors: I. Foeldvari, M. Katsicas, M. Teresa Terreri, R. Cimaz, M. Kostik, F. Sztajnbok, D. Nemcova, M. Moll, M. Jose Santos, T. Avcin, J. Brunner, S. Nielsen, T. Kallinich, K. Minden, J. Mueller, M. Janarthanan, Y. Uziel, W.A. Sifuentes-Giraldo, D. Eleftheriou, K. Torok, N. Helmus
Journal: Annals of the Rheumatic Diseases (2015)

<h3>Background</h3> Juvenile systemic sclerosis (jSSc) is an orphan autoimmune disease. Currently just retrospective data exist regarding evolvement of organ involvement. In the previous retrospective studies assessment of the organ involvement was not standardized. Our project is the first one, where data of jSSc patientes were collected prospectively and with a standardized assessment. <h3>Objectives</h3> To learn about the characteristics and evolvement of organ involvement in jSSc <h3>Methods</h3> Patients with jSSc were recruited worldwide and were prospectively assessed, using the proposed standardized patient assessment protocol. Data of the juvenile systemic sclerosis inception cohort have been contributed to the DeSScipher project which was funded by a grant of theEuropean Community9s Framework Programme 7 under grant agreement N° 305495." <h3>Results</h3> 44 centers from 24 countries aggreed to participate on the project. The assent and consent forms were translated into the local native languages. Untill now 39 patients have been enrolled with a mean disease duration of 6.1 years. Thirty (77%) of the 39 patients were females. The mean age of the onset of Raynaud9s phenomenon was 9.7 years (2-16 years), the youngest 2 years old. The mean age at the onset of the non-Raynaud presentation of jSSc was 10.3 years (3.0-16.00years). 29 (74%) of the 39 have diffuse subtype. 5 in the diffuse (17%) and 3 in the limited subtype (30%) had an overlap feature. At the time of the inclusion the mean modified Rodnan Skin Score was 16.5. 26/37 had already capillary changes and 22/37 already history of ulcerations, 9/37 had active ulcerations at the time of the inclusion. 26/39 had cardiopulmonary involvement, 11/39 presented with signs of interstitial lung disease on imaging. Two patients had pulmonary hypertension. Three had renal involvement, but no renal crisis. 16/39 had gastrointestinal involvement and 11 of them esophageal involvement. 30/38 had musculoskeletal involvement. ANA positivity occurred in 30/36 and 12/30 of them were anti-Scl 70 positive. 1/23 had anticentromere positivity. <h3>Conclusions</h3> We present the data on the first 39 patients with jSSc included in our cohort. The current recruitment data confirms that pediatric patients are different from the adult patients, with a higher proportion of diffuse subset patients with 74% and of patients with overlap features. <h3>Disclosure of Interest</h3> None declared
Notes on the Newer Remedies; Their Therapeutic Applications and Modes of Administration.
Journal: JAMA (1895)

This little book,which is dedicated to Prof. Horatio C.Wood, of Philadelphia, has a great field of usefulness. The newer remedies are described by the medical press as they are reported, from time to time, and occasionally mentioned in case reports, but the author has here gathered them together in one volume, and briefly given a definition, an account of the physical properties, solubility, physiologic action, therapeutic application and dosage of each. We are pleased to note that the decimal system of dosage has been employed. In most cases both the British and the metric dose is given. The volume is a useful one and should have a large distribution.
Rheumatological stamp
Authors: Yale Andelman
Journal: Annals of the Rheumatic Diseases (1993)

What will be the impact of this information?It is likely that more children will be labelled as having a pain syndrome, but the importance of labelling alone should certainly be open to question.Does it make a difference if these conditions are diagnosed or not?It is not yet possible to answer this question scientifically, but the answer will hopefully be yes.Chronic musculoskeletal pain in children, even in the absence of an organic cause, can result in significant physical incapacity, loss of schooling, and social disruption."6The problems may be exacerbated through an unsympathetic approach, excessive laboratory investigations, diagnostic uncertainty, and inappropriate treatment.3New approaches to diagnosis and enhanced understanding of pathogenesis, may eventually decrease the morbidity and improve the outlook for children with chronic musculoskeletal pain.
Patients' reactions to psychiatric consultation
Authors: L. M. Koran
Journal: JAMA (1979)

Physicians are often concerned that patients will resent a request for psychiatric consultation. To investigate this problem, 60 patients undergoing psychiatric consultation in a general hospital were interviewed 24 hours after the consultation. Nearly two thirds of these patients believed that the consultation was beneficial. Patients' attitudes were independent of their demographic characteristics, reason for referral, and hospital service involved. Patients with long-term illnesses more often had positive attitudes than patients with short-term illnesses. Patients who were initially hostile or ambivalent usually had positive attitudes 24 hours later. Substance abusers and patients who denied clearly recognizable psychiatric disorders often did not value the consultation. Even so, their physicians frequently believed that the consultation was useful. We attribute the positive attitudes of patients in our study largely to the referring physicians' preparing them for psychiatric consultation. (<i>JAMA</i>241:1603-1605, 1979)
Sergei Sergeivich Korsakov (1853-1900). Korsakov's psychosis
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Spontaneous Pneumothorax
Authors: Gerard Desforges
Journal: New England Journal of Medicine (1962)

SPONTANEOUS pneumothorax may present a variable symptomatology. The clinical picture of pain in the chest associated with varying degrees of shortness of breath is well known to any practicing physician. It occurs most commonly in young men between the ages of twenty and forty. Anamnesis may reveal similar occurrences in the past that the patients may have ignored because of the minor symptomatology of the episode. Confirmation of the suspected diagnosis by x-ray examination of the chest is mandatory. Although physical examination may reveal the classic signs in total pneumothorax it is often not helpful in cases with less involvement. . . .
Addition of Inadvertently Omitted Financial Disclosures
Authors: Benjamin Smith, Eric Hoffman, R Graham Barr
Journal: JAMA (2020)

In Reply Variation in human airway tree structure can take many forms.As Dr Uzoigwe points out, our research team has, to date, investigated variations in airway branch patterns and airway tree caliber and their associations with COPD. 1,2We note that these associations are complex and agree that unraveling the causal relationship between airway tree structure and COPD requires further investigation.However, we disagree that airway branch patterns and dysanapsis are one and the same phenomenon.The association between dysanapsis and incident COPD remains large and statistically significant when additionally adjusted for the airway branch patterns previously linked to COPD 2 (eg, the adjusted rate ratio for incident COPD comparing the smallest with largest airway to lung ratio in the Multi-Ethnic Study of Atherosclerosis [MESA] Lung Study is 7.81 [95% CI, 3.68-16.57;P < .001]).As Uzoigwe points out, presence of an accessory central airway has been associated with COPD.Yet this common branch variant was not associated with differences in lung volume, 2 central airway tree caliber, 2 or dysanapsis (eg, the mean difference in airway to lung ratio compared with standard anatomy in the MESA Lung Study was 0.000 [95% CI -0.0003 to 0.0004; P = .93]).These observations support the hypothesis that variation in airway branch patterns and dysanapsis may be independent risk factors for COPD.Dysanapsis was also associated with incident COPD among those who have never smoked. 1 We therefore do not think that the association between dysanapsis and COPD is due to altered deposition of tobacco smoke and other particulates, although association modifications related to environmental exposures merit further investigation.
Digitalis Glycosides
Authors: Thomas W. Smith
Journal: New England Journal of Medicine (1973)

A DECADE has passed since the clinical use of cardiac glycosides was last reviewed in these pages.1 Despite continuing uncertainty regarding fundamental mechanisms of action at the cellular and molecular level, recent progress allows a more rational approach to the clinical use of these drugs. A sound working knowledge of the actions and pharmacokinetics of the commonly used cardiac glycosides should improve the patient's chances of benefiting from the use of digitalis and allow a substantial reduction of the present alarming frequency of toxicity.Sources and Structure-Activity RelationsThe term digitalis is used generally to refer to any of the . . .
Pondering How to Squeeze Fitness Programs Into Schools' Budgetary, Time Constraints
Authors: Charles Marwick
Journal: JAMA (1992)

SOME FITNESS advocates suggest that children's exercise programs are barely jogging along. Ever-tighter budgets and increased pressures to include more academic subjects are said by exercise advocates like Judith C. Young, PhD, executive director of the National Association for Sport and Physical Education (Reston, Va), to be threatening physical education programs in schools. On the other hand, while it might seem obvious that increased physical activity—especially started early in life— would significantly reduce cardiovascular risk factors, current data are not adequate to state this conclusively, says Michael A. Nelson, MD. Nelson is chair of the American Academy of Pediatrics (Elk Grove Village, Ill) Committee on Sports Medicine and Fitness. Whatever the longer-term outcome,
Shoulder Lesions
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Exemestane for primary prevention of breast cancer in postmenopausal women: NCIC CTG MAP.3—A randomized, placebo-controlled clinical trial.
Authors: P. E. Goss, J. N. Ingle, J. Ales-Martinez, A. Cheung, R. T. Chlebowski, J. Wactawski-Wende, A. McTiernan, J. Robbins, K. Johnson, L. Martin, E. Winquist, G. Sarto, J. E. Garber, C. J. Fabian, P. Pujol, E. Maunsell, P. Farmer, K. A. Gelmon, D. Tu, H. Richardson
Journal: Journal of Clinical Oncology (2011)

LBA504 The full, final text of this abstract will be available in Part II of the 2011 Annual Meeting Proceedings, distributed onsite at the Meeting on June 4, 2011, and as a supplement to the June 20, 2011, issue of Journal of Clinical Oncology.
Map of the World Distribution of Malaria Vectors
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Simple Treatment for Tuberculosis.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PHYSICIANS AND LABOR ORGANIZATIONS.
Journal: JAMA (1902)

In organizing a physicians' protective association in California recently it appears that inquiries were made by some parties as to its possible affiliation with the American Federation of Labor. The following letter, taken from the<i>Stockton</i>(Cal.)<i>Independent</i>, explains the status of medical men in relation to that body, and will be taken, we trust, as conclusive enough to prevent any future suggestions of the kind: Washington, D. C., Nov. 26, 1902. Mr. H. M. Alexander, Organizer A. F. of L., Record Building, Stockton, Cal. <h3>Dear Sir and Brother:</h3> Your favor of November 18 at hand, and contents noted. I beg to inform you that it is against the principles of the American Federation of Labor to issue charters to professional men. The only union which is made up of men engaged in different crafts and calling is federal labor, but even in this it is stipulated that only wage
Chlamydial Infections
Authors: Joel L. Nitzkin
Journal: JAMA (1975)

<h3>To the Editor.—</h3> In a recent article (231:1252, 1975), Schachter et al discussed the high prevalence of chlamydial infections in nonvenereal disease clinics under the title, "Are Chlamydial Infections the Most Prevalent Venereal Disease?" Nowhere in their paper did they deal with the question of mode of transmission to the infection seen. If they believe that they have evidence to indicate that the chlamydial infections observed were sexually transmitted, such data should have been presented within the paper. If such data do not exist, their title is clearly inappropriate.
Genomic Priming of the Antisecretory Response to Estrogen in Rat Distal Colon throughout the Estrous Cycle
Authors: Fiona O'Mahony, Rodrigo Alzamora, Ho-Lam Chung, Warren Thomas, Brian J. Harvey
Journal: Endocrine Reviews (2009)

ABSTRACT The secretion of Cl− across distal colonic crypt cells provides the driving force for the movement of fluid into the luminal space. 17β-Estradiol (E2) produces a rapid and sustained reduction in secretion in females, which is dependent on the novel protein kinase Cδ (PKCδ) isozyme and PKA isoform I targeting of KCNQ1 channels. This sexual dimorphism in the E2 response is associated with a higher expression level of PKCδ in female compared with the male tissue. The present study revealed the antisecretory response is regulated throughout the female reproductive (estrous) cycle and is primed by genomic regulation of the kinases. E2 (1-10 nm) decreased cAMP-dependent secretion in colonic epithelia during the estrous, metestrous, and diestrous stages. A weak inhibition of secretion was demonstrated in the proestrous stage. The expression levels of PKCδ and PKA fluctuated throughout the estrous cycle and correlated with the potency of the antisecretory effect of E2. The expression of PKCδ and PKA were up-regulated by estrogen at a transcriptional level via a PKCδ-MAPK-cAMP response element-binding protein-regulated pathway indicating a genomic priming of the antisecretory response. PKCδ was activated by the membrane-impermeant E2-BSA, and this response was inhibited by the estrogen receptor antagonist ICI 182,780. The 66-kDa estrogen receptor-α isoform was present at the plasma membrane of female colonic crypt cells with a lower abundance found in male colonic crypts. The study demonstrates estrogen regulation of intestinal secretion both at a rapid and transcriptional level, demonstrating an interdependent relationship between both nongenomic and genomic hormone responses.
RESPONSIBILITY FOR RECRUITMENT
Authors: J. H. T.
Journal: JAMA (1960)

The competition for talent in the professional schools in America is a fact of life that must be accepted by the physician in today's world. This should not be a disheartening admission; rather, competition in this endeavor, as in many, should enhance the wits of the contenders and bring into sharp prospectus the ways and means of preventing dire consequences. Of great concern at the moment is the need to attract a sufficient number of intellectually and emotionally qualified high school and college students to fill the ranks of the first year classes in our medical schools each Fall. In so doing, we are obviously competing with the graduate schools of chemistry, physics, mathematics, engineering, and a myriad of others that are as interested in quality talent as are the admissions committees of the several medical schools. It is vital that there be a steady supply of apt, able, and
State-Specific Prevalence of Lapses in Health-Care–Insurance Coverage—United States, 1995
Journal: JAMA (1998)

Lack of health-care-insurance coverage has been associated with decreased use of preventive health services, delay in seeking medical care, and poor health status. In 1995, an estimated 30.5 million persons aged 18-64 years in the United States did not have health insurance. To determine state-specific estimates of the prevalence of persons aged 18-64 who reported either short-term (i.e., <12 months) or long-term (i.e., > or = 12 months) lapses in health-care coverage, CDC analyzed data from the 1995 Behavioral Risk Factor Surveillance System (BRFSS). This report summarizes the results of that analysis and indicates that among adults who reported having no health insurance in 1995, most were without insurance for > or = 1 year and that long-term lapses were more prevalent among men than women.
Dogwoods
Authors: John P Wynne
Journal: Annals of Internal Medicine (2012)

On Being a Doctor19 June 2012DogwoodsJohn P. Wynne, MDJohn P. Wynne, MDFrom Carolinas Medical Center, Charlotte, NC 28203.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-156-12-201206190-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Mrs. M. had another infection. She had blood in her urine. As she talked, she began trembling, then crying, before asking me, “Is my cancer back? Please, please tell me it's not the cancer.” I was stunned at the conversation. Stunned because Mrs. M. was obviously dying.She had a heart attack 2 weeks before our meeting, which had required stenting. She had been treated for colon cancer, bladder cancer, and pneumonia; her medical history ran on and on. She had become emaciated and too weak to use the bathroom and had to wear diapers continuously. She was developing urinary ... Author, Article, and Disclosure InformationAffiliations: From Carolinas Medical Center, Charlotte, NC 28203.Corresponding Author: John P. Wynne, MD, Carolinas Medical Center, 1000 Blythe Boulevard, Charlotte, NC 28203; e-mail, john.[email protected]org. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 19 June 2012Volume 156, Issue 12Page: 898-899KeywordsCardiopulmonary resuscitationHealth careMyocardial infarctionOxygenPneumoniaResidencySleepUrinary tract infectionsUrineVentilators ePublished: 19 June 2012 Issue Published: 19 June 2012 Copyright & PermissionsCopyright © 2012 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Massachusetts Department of Public Health
Authors: Johannes Ipsen
Journal: New England Journal of Medicine (1954)

A health department should take stock of the achievements of its programs as soon as significant data can be studied. Since 1949 the Biologic Laboratories have made available for general use in children the "triple vaccine" for immunization against pertussis, diphtheria and tetanus. Tetanus immunization was undoubtedly practiced by physicians and clinics some years before 1949, but the annual issue of over 100,000 doses of the triple vaccine for the last four years, equivalent to the number of children born annually in the Commonwealth of Massachusetts, indicates that it is now the practice to immunize the great majority of young . . .