tbuckley/cabot-search huggingface dataset:
Medicine and media: The role of journalism in public health education
Authors: K. K. Chan, F. A. Quereshy, W. Melnick, L. L. Siu
Journal: Journal of Clinical Oncology (2004)

6090 Background: Public dissemination of medical information via the media requires journalists' research on the subject matter and their interactions with doctors or scientists. About 70% of cancer patients search the media for information, and one-third feels that their decisions are influenced by this information (Chen and Siu, J Clin Oncol, 2001). This study aimed to understand the media's perception of its role in the dissemination of medical information. Methods: Twenty-five Canadian medical journalists from various media sources (newspaper (NP), magazine (M), radio (R) and television (TV)) were contacted. A structured telephone interview was conducted to evaluate research strategy and perception of role. Responses were analyzed qualitatively. Results: The response rate was 64% (16/25): 5 NP, 4 M, 1 R and 6 TV. Most (13/16) did not have prior health-related education. In identifying a news story, NP considered the potential to change the standard of care the most important element, whereas for TV existent public interest was the most important. Most used medical journals to identify a news story, and utilized sources including expert opinions, authors of original studies, journals, internet and textbooks for research. Internet was consistently used for background research. Most (9/16) perceived the primary role of the media as initiating public interest instead of providing comprehensive health information. Most felt that the media equipped patients to ask questions, to challenge authority and to improve communications with doctors. All but one felt that the media had a positive impact on the doctor-patient relationship. Some (6/16) commented that doctors could not simplify their language. Doctors are felt to be hesitant about communicating with the media. Timely responses from doctors and an organized forum for doctors and journalists to interact were suggested as possible ways to assist the media in public education. Conclusions: The media perceived the lack of proper communication between doctors and journalists as a barrier to the public dissemination of medical information. Future interventions should aim to improve such communication and improve public health education. No significant financial relationships to disclose.
The Resistance of Various Nerve-Cells to Anemia
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
This Week in &lt;emph&gt;JAMA&lt;/emph&gt;
Journal: JAMA (2008)

A Piece of My Mind" [H]ere was a 50-year-old woman with a wound that seemed so harsh and raw, cruelly robbing her of a vital piece of her external femininity."From "Wound Healing." SEE PAGE 1647 Medical News & PerspectivesA new online tool aims to help primary care physicians in a variety of settings better assess fracture risk in patients with low bone mass.
Preliminary Studies on the Reduction and Binding of Chromium With Skin
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effect of PDL1 expression [exp] on overall survival [OS] in patients [pts] with metastatic adenocarcinoma lung [MAC]: Illinois CancerCare [ILCC] analysis.
Authors: Allison Frey, Pankaj Kumar, Jamie Harper
Journal: Journal of Clinical Oncology (2018)

e21125 Background: Effect of PDL1 on OS in patients with MAC is controversial. This relationship has not been studied methodically in US midwestern population, a largely homogenous Caucasian group. We examined this question at ILCC, one of the largest practices in US midwest. Methods: We conducted a retrospective analysis of all MAC pts who presented at ILCC in 2016. PDL1 status was defined as: high if PDL1 was > 50%, low if 5-50% & -ve if 0-5%. High and low groups together were called +. Statistical analysis was performed using the log rank Kaplan-Meier method. Results: In 2016 there were 213 pts seen at ILCC with MAC. As of 12/2016, 121/213 [51%] pts were alive. Pt characteristics: median age 63 yrs [31-89], median PS 1 [0-3], males 50%, current/former smokers 95%, Caucasians 95%. PDL1 results were available in 79/213 [37%]. 44/79 pts [56%] received anti PDL1 antibodies Nivolumab, Pembrolizumab & Atezolizumab. 24/44 pts were PDL1+ and 20/44 were -ve. Median OS of PDL1+ pts were: high PDL1 expressers [ > 50%] 10.43 months [m] & low exp [5-50%] 18.23 m. There was no statistical difference in OS in these groups [p = 0.948]. We also evaluated this relationship between total PDL1+ pts [high and low expressers together] and PDL1- ve pts. We did not find any difference between these groups either. Median OS of PDL1+ was 12.1 m & PDL1 -ve was 12.3 m [p = 0.948]. Conclusions: Our study suggests that OS of our MAC pts is not influenced by PDL1 status. The potential influence of patient ethnic, genetic & molecular biomarker traits on OS needs to be explored further.
Mercury Exposure in a High School Laboratory— Connecticut
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Association News
Authors: Archer O'Reilly
Journal: JAMA (1923)

<h3>THE CHICAGO SESSION</h3> Section on Orthopedic Surgery To Fellows of the American Medical Association: Any Fellow who desires to present a paper before the Section on Orthopedic Surgery at the Chicago session is requested to write to the secretary before Jan. 1, 1924. The title of the paper and a brief outline of its scope must be submitted with the application in order to secure consideration. Papers to be put on the final program will be selected shortly after January 1 by the Executive Committee.
Phase II/III study of circulating tumor DNA as a predictive biomarker in adjuvant chemotherapy in patients with stage II colon cancer: NRG-GI005 (COBRA).
Authors: Van K. Morris, Greg Yothers, Scott Kopetz, Samuel A. Jacobs, Peter C. Lucas, Atif Iqbal, Patrick M Boland, Dustin A. Deming, Aaron James Scott, Howard John Lim, Norman Wolmark, Thomas J. George
Journal: Journal of Clinical Oncology (2020)

TPS4121 Background: There are currently no validated predictive biomarkers for stage II resected colon cancer (CC) after adjuvant chemotherapy. However, circulating tumor DNA (ctDNA) that is shed into the bloodstream represents a highly specific and sensitive approach for identifying microscopic or residual tumor cells. For patients (pts) with CC, the detection of ctDNA is associated with persistent disease after resection and may outperform traditional clinical and pathological features as a prognostic factor to assess risk for recurrence. We hypothesize that for pts whose stage II colon cancer has been resected and who have no traditional high-risk features, a positive ctDNA status may identify those who will benefit from adjuvant chemotherapy. Methods: In this prospective phase II/III clinical trial, pts (N=1,408) with resected stage II CC without traditional high-risk features and whom the evaluating oncologist deems suitable for no adjuvant chemotherapy will be randomized 1:1 into 2 arms: standard-of-care/observation (Arm A), or prospective testing for ctDNA (Arm B). Postoperative blood will be analyzed for ctDNA with the GuardantHealth LUNAR panel, covering CC-relevant mutations and CC-specific methylation profiling. Pts in Arm B with ctDNA detected will be treated with 6 months of adjuvant (FOLFOX) chemotherapy. For all pts in Arm A, ctDNA status will be analyzed retrospectively at the time of endpoint analysis. The primary endpoints are clearance of ctDNA with adjuvant chemotherapy (phase II) and recurrence-free survival (RFS) for “ctDNA-detected” pts treated with or without adjuvant chemotherapy (phase III). Secondary endpoints will include time-to-event outcomes (OS, RFS, TTR) by ctDNA marker status and treatment, prevalence of detectable ctDNA in stage II CC, and rates of compliance with assigned intervention. Archived normal and matched tumor and blood samples will be collected for exploratory correlative research. The trial is actively accruing towards the phase II endpoint across all US and Canadian cooperative groups. Support: U10-CA-180868, -180822; UG1CA-189867; GuardantHealth. Clinical trial information: NCT04068103 .
THE COST OF BURIAL
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Extensive hypertensive work-up: pro
Authors: J. C. Melby
Journal: JAMA (1975)

IT IS estimated that approximately 20% of the adult population in the United States has arterial hypertension, with blood pressures at or above 160/95 mm Hg on repeated examination.<sup>1</sup>It is also conceded that arterial hypertension is the most important risk factor for congestive cardiac failure, stroke, and renal failure, and it is among the most important risk factors for coronary artery disease.<sup>2-4</sup>Furthermore, it has been established that the treatment of arterial hypertension will effectively prevent complications of stroke, congestive heart failure, and renal failure. As a public health issue, it is conceded that it would be desirable to detect and to treat all hypertensive patients. Because of the epidemic proportions of the hypertension problem, thoughtful clinicians would like to reduce to an essential minimum the diagnostic evaluation, cost of workup, and inconvenience. I assume, logically, that it is to the patient's benefit to begin one of
Neuropathology: The Anatomical Foundation of Nervous Diseases.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Advances in Enzymology and Related Subjects of Biochemistry. Volume XII
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nonalcoholic Steatohepatitis
Authors: Richard H. Moseley
Journal: Annals of Internal Medicine (1997)

Letters1 September 1997Nonalcoholic SteatohepatitisRichard H. Moseley, MDRichard H. Moseley, MDAnn Arbor Veterans Affairs Medical Center; Ann Arbor, MI 48105Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-5-199709010-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:I read with interest the excellent review of NASH by Sheth and colleagues [1]. The recommendation that liver biopsy be done in all patients with abnormal liver test results and negative results on a noninvasive evaluation deserves comment. Although the ability to diagnose fatty liver without a biopsy specimen was poor, the positive predictive value of a prebiopsy diagnosis of chronic necroinflammatory disease, such as NASH, was 81% [2]. Serum aminotransferase values exceeding three times the upper limit of normal also increased the accuracy of the prebiopsy diagnosis [2]. Furthermore, there is no proven treatment for NASH, ...References1. Sheth SG, Gordon FD, Chopra S. Nonalcoholic steatohepatitis. Ann Intern Med. 1997; 126:137-45. Google Scholar2. Van Ness MM, Diehl AM. Is liver biopsy useful in the evaluation of patients with chronically elevated liver enzymes? Ann Intern Med. 1989; 111:473-8. Google Scholar3. Laurin J, Lindor KD, Crippin JS, Gossard A, Gores GJ, Ludwig J, et al. Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: a pilot study. Hepatology. 1996; 23:1464-57. Google Scholar4. Van Leeuwen DJ, Wilson L, Crowe DR. Liver biopsy in the mid-1990s: questions and answers. Semin Liver Dis. 1995; 15:340-59. Google Scholar5. Roenigk HH. Methotrexate and liver biopsies: is it really necessary? Arch Intern Med. 1990; 150:733-4. Google Scholar Author, Article, and Disclosure InformationAffiliations: Ann Arbor Veterans Affairs Medical Center; Ann Arbor, MI 48105 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 September 1997Volume 127, Issue 5Page: 410-411KeywordsBiopsyLiverMethotrexateNonalcoholic steatohepatitisOverweightPathogenesisPhosphatasesPositive predictive valueSteatosisWeight loss Issue Published: 1 September 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
OlympiAD: Phase III trial of olaparib monotherapy versus chemotherapy for patients (pts) with HER2-negative metastatic breast cancer (mBC) and a germline BRCA mutation (gBRCAm).
Authors: Mark E. Robson, Seock-Ah Im, Elżbieta Senkus, Binghe Xu, Susan M. Domchek, Norikazu Masuda, Suzette Delaloge, Wei Li, Nadine M. Tung, Anne Armstrong, Wenting Wu, Carsten Dietrich Goessl, Sarah Runswick, Pier Franco Conte
Journal: Journal of Clinical Oncology (2017)

LBA4 The full, final text of this abstract will be available at abstracts.asco.org at 7:30 AM (EDT) on Sunday, June 4, 2017, and in the Annual Meeting Proceedings online supplement to the June 20, 2017, issue of the Journal of Clinical Oncology. Onsite at the Meeting, this abstract will be printed in the Sunday edition of ASCO Daily News.
Acute gouty arthritis. The diagnostic importance of aspirating more than one involved joint
Authors: M. Abeles
Journal: JAMA (1977)

MONOSODIUM urate crystals in synovial fluid aspirated from a person with an attack of acute arthritis is the sine qua non for diagnosis of gout.<sup>1</sup>However, in an occasional patient with acute gout, urate crystals cannot be found in fluid from the aspirated joint.<sup>2</sup>A case of gout was found in a man with two nonadjacent sites of acute arthritis, one yielding synovial fluid with urate crystals, the other without urate crystals. <h3>Report of a Case</h3> A 31-year-old man was admitted to the emergency room of the University of Connecticut Health Center with complaints of pain and swelling of three days' duration in the right ankle and knee. History included a similar episode of pain and swelling in his right ankle and knee 1 1/2 years before this admission. At that time, he was told he had "arthritis or gout." Diagnostic studies were not performed, nor was aspiration
ADDITIONAL ALCOHOLIC COMPOUNDS TO BE TAXED.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal