tbuckley/cabot-search huggingface dataset:
The 'incidentaloma' of the pituitary gland. Is neurosurgery required?
Authors: M. Reincke
Journal: JAMA (1990)

We describe a series of 18 patients with an intrasellar mass incidentally discovered by computed tomography or magnetic resonance imaging. The average size of the mass was 13 mm, with a range from 5 to 25 mm. Initial ophthalmologic examination revealed bitemporal hemianopia in 2 patients. Results of routine endocrine testing showed partial hypopituitarism in 5 patients and growth hormone hypersecretion without signs and symptoms of acromegaly in 1 patient. Four patients underwent neurosurgery. Histologically, one chondroid chordoma and three pituitary adenomas were found. In the remaining 14 patients treated conservatively, repeated computed tomography and magnetic resonance imaging revealed no significant change in tumor size at the time of follow-up (median, 22 months). Our results suggest that the "incidentaloma" of the pituitary gland is a benign condition that does not necessarily require neurosurgical intervention. (<i>JAMA</i>. 1990;263:2772-2776)
Resource-based relative values. An overview
Authors: W. C. Hsiao
Journal: JAMA (1988)

Studies have been conducted over the past decade to develop a Resource-Based Relative Value Scale (RBRVS) for physicians' services. Policymakers view an RBRVS as a potential tool to pay physicians. The Physician Payment Review Commission, under a congressional mandate, has endorsed the general concept of a fee schedule based on resource costs for physician payment under Medicare. In this overview article, we present the policy context in which the RBRVS may play a role and describe the approach taken to develop this scale, specifically consultation with clinicians, researchers, and insurers and data gathering, including a national survey of physicians. We discuss underlying elements that are necessary to constructing an RBRVS, each of which is described more fully in subsequent articles: measuring the work (intraservice work) of performing medical services and procedures, estimating preservice and postservice work, comparing work across specialties, measuring practice costs, extrapolating from surveyed services, and establishing an RBRVS for evaluation/management services and for invasive procedures. Overall results are presented in a companion article. (<i>JAMA</i>1988;260:2347-2353)
Senility Reconsidered
Authors: J. Thomas Hutton
Journal: JAMA (1981)

<h3>To the Editor.—</h3> The task force sponsored by the National Institute on Aging described (1980;244:259) numerous causes of mental impairment in the elderly and identified a need to determine the frequency of reversible causes for this syndrome. The previous studies cited suffer from being retrospective and reporting potentially reversible causes rather than true outcome of therapy.<sup>1,2</sup>I would like to report the findings of a recently completed prospective study of 100 consecutive patients seen for apparent mental impairment and to relate their treatment outcomes. Standard diagnostic criteria described elsewhere were employed.<sup>3</sup>Of the 100 cases evaluated for apparent dementing illnesses, eight were found not to have mental impairment. The remaining 92 cases were diagnosed as follows: probable Alzheimer's type dementia (22); diffuse or Korsakoff's alcoholic dementia (12); functional psychiatric disorders (18); multiinfarct dementia (12); CreutzfeldtJakob disease (2); nutritional, metabolic, or endocrine disturbances (9); space-occupying lesions (4); occult hydrocephalus
Traité de physiologie, normale et pathlogique
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE PRESENT STATUS OF MEDICAL LEGISLATION IN THE UNITED STATES.
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Vincristine sulfate and cyclophosphamide for children with metastatic neuroblastoma
Authors: A. E. Evans
Journal: JAMA (1969)

Thirty-eight children with metastatic neuroblastoma were given a combination of vincristine sulfate and cyclophosphamide in addition to standard surgical and radiotherapeutic management. The two agents were given intravenously on alternating weeks for 12 weeks or longer. Results were best in eight infants under 1 year, five of whom continued to survive free of disease for 16 months. The overall response rate in patients of all ages was 32% (nine out of 28), and the mean survival was 12 months. The combination of the two agents was effective.
The diverse genomic landscape of low-risk prostate cancer.
Authors: Matthew R. Cooperberg, Nicholas Erho, June M. Chan, Felix Yi-Chung Feng, Janet E. Cowan, Kaye Ong, Mohammed Alshalalfa, Tyler Kolisnik, Jennifer Margrave, Maria Aranes, Marguerite du Plessis, Christine Buerki, Shuang Zhao, Imelda Tenggara, Elai Davicioni, Peter Carroll
Journal: Journal of Clinical Oncology (2017)

72 Background: Active surveillance (AS) is becoming standard of care for men with low-risk prostate cancer; however a need exists for better tools to assess which men are optimal candidates for AS. In this study we compare genomic expression profiles of AS candidates against higher-risk radical prostatectomy (RP) patients to characterize the genomics of clinically low-risk prostate cancer. Methods: Biopsies from 473 UCSF patients potentially suitable for AS (stage ≤ cT2N0M0, PSA ≤ 10 ng/ml, Gleason 3+3 or low-volume 3+4 ) were profiled using the Affymetrix HuEx microarray to generate RNA expression data. These cases were compared to 2043 RP cases previously profiled on the same microarray platform. Scores for 21 published prognostic signatures were calculated and pathway associated genes were summarized to provide levels of patient risk and pathway activity. Results: Of the 473 AS biopsies profiled, 408 (86%) passed quality control and were used for analysis. Based on the quartiles of average scores for 21 prognostic signature risk models, 49%, 36%, 11%, and 4%, respectively, were classified into the 1st, 2nd, 3rd, or 4th score quartiles. Considering only the clinically low-risk patients at diagnosis, 356 (87%) were low, 45 (11%) were intermediate and 7 (2%) were high risk. Genomic risk was positively associated with cell cycle related pathways (p &lt; 0.001) and negatively associated with apical junction (p &lt; 0.001), epithelial−mesenchymal transition (p &lt; 0.001), and androgen receptor (p &lt; 0.05) pathways. Clustering of patients based on the expression of 36 pathways revealed two biologic groups corresponding to putative basal and luminal subtypes. Compared to higher risk RP patients, the low risk prostate cancer tumors at diagnosis were enriched for basal-like tumors (20% vs 33%, p &lt; 0.001). Conclusions: Although only 2% of low risk AS candidates have high risk genomic characteristics, very substantial genomic heterogeneity exists in this population, and pathway activation overlaps significantly with higher-risk RP patients. These results suggest that even in potential AS candidates, genomic profiling could eventually be used to better guide management.
THE TONSILS A GATEWAY FOR INFECTION.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AMA Policy Promotion Grants
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hospital security
Authors: J. Phillips, M. Soskin
Journal: BMJ (1995)

Gains (years) in life expectancy with reduction in riskfactors.Figures are means (95% confidence intrals) For 40 year old man (coronary heart disease Intervention prevention model)' For 45 year old man (meta-analysis application)' Stopping smoking 4 9 3-84 (3-68 to 4 04) Reducing blood pressure 09 0-83 (-007 to 179) Lowering cholesterol 1-2 -0-01 (-0-78 to 0-66)
Medicinal herbs: NTP extracts the facts.
Journal: Environmental Health Perspectives (1999)

The National Toxicology Program (NTP) has announced that it will design and initiate studies to identify and characterize possible adverse health effects that may be associated with prolonged use or higher doses of some of the most popular medicinal herbs, including Ginkgo biloba, Echinacea angustifolia, and Panax quinquefolius (American ginseng). The NTP studies a large variety of substances to which the population may be exposed in the environment, occupationally, in the food supply, or elsewhere.
Leads from the MMWR. Regional variation in smoking prevalence and cessation: Behavioral Risk Factor Surveillance, 1986
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mortality and cancer morbidity in a group of Swedish VCM and PCV production workers
Authors: D Byrén, G Engholm, A Englund, P Westerholm
Journal: Environmental Health Perspectives (1976)

The cohort of workers employed in a Swedish vinyl chloride/poly(vinyl chloride) plant since its start in the early 1940's has been followed for mortality and cancer morbidity patterns.Only 21 of the 771 persons could not be traced.Difficulties in establishing ex- posure levels at different work areas in the past makes an evaluation of dose-effect relationships impossible.A four-to fivefold excess of pancreas/liver tumors was found, including two cases later classified as angiosarcomas of the liver.The number of brain tumors and suicide do not deviate significantly from expected.Cardiovascular and cerebrovascular diseases, on the other hand, differ significantly from the expected.The discrepancies between previous reports on VCM/PVC workers and this report are discussed.The possible eti- ology of the cardiovascular deaths is also discussed.A review of known health effects of VCM and PVC has been published by Holmberg et al.(1) .Monson et al.(2) found a 50% excess of deaths due to all cancer in a proportionalmortality analysis of deaths among workers in two plants using vinyl chloride.The greatest excess was observed in liver, lung, and brain cancers.There was also a twofold excess of sui- cide.A recent report by Duck et al.(3) on the age-standardized mortality rates for workers exposed to vinyl chloride did not show any ex- cess of total or cause-speCific mortality.One case of angiosarcoma of the liver was found.Baxter and Fox (4) recently reported on the proportional mortality for deaths among male plastic workers in England and Wales (1970- 1972).The only significant excess of deaths was found in stomach cancer and diseases of the urogenitary system.All cancer, cancer of the
DANIEL WHISTLER (1619-1684) THE RICKETS
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The British Olympic Association's position statement on athlete confidentiality
Journal: British Journal of Sports Medicine (2000)

The Professional Code of Conduct of medical andscientific support staff limits their freedom to report injuries, illnesses and other problems identified to anyone else other than the athlete (individual) directly concerned. The British Olympic Association recognises how important it is that coaches, managers, administrators and other team officials are fully aware of the limitations on communication imposed by this duty of confidentiality.
Infectious Diseases
Authors: Mary Bessesen
Journal: Annals of Internal Medicine (2008)

Medical Writings: Book Notes16 September 2008Infectious DiseasesMary Bessesen, MDMary Bessesen, MDFrom Veterans Affairs Medical Center University of Colorado Health Sciences Center, Denver, Colorado.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-149-6-200809160-00025 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Infectious DiseasesSecond edition. Tan JS, Tan MJ, Salata RA, File TM Jr, eds. 900 pages. Philadelphia: American Coll of Physicians; 2007. $69.95. ISBN 9781930513853. Order at www.acponline.org.Field of medicine: Infectious disease.Format: Softcover book.Audience: Primary care physicians, medical students, and other health care providers interested in the evaluation and management of common infectious diseases, as well as their underlying pathophysiology.Purpose: To provide current information on common infectious diseases encountered in primary care office practice.Content: This text, with contributions from prominent academic physicians with extensive clinical experience, begins with a concise yet thorough discussion of the ... Author, Article, and Disclosure InformationAffiliations: From Veterans Affairs Medical Center University of Colorado Health Sciences Center, Denver, Colorado. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 16 September 2008Volume 149, Issue 6Page: 440KeywordsHIV infectionsHealth care providersInfectious diseasesMicrobiologyPrimary care physiciansResearch laboratoriesSkin infectionsSoftware toolsTreatment guidelinesVeteran care ePublished: 16 September 2008 Issue Published: 16 September 2008 Copyright & PermissionsCopyright © 2008 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Health Agencies Update
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Notices
Journal: Hepatology (1991)

The course will be followed by the 42nd Annual Meeting of the American Association for the Study of Liver Diseases on November 4 and 5, 1991.The course is intended for physicians, academicians and researchers who use liver biopsy in practice or clinical research and want to update their knowledge of liver histopathology.The purpose of the meeting is to review important issues in liver biopsy interpretation, with an emphasis on how liver biopsy can elucidate problems of differential diagnosis.The course is based on syndromes and clinical presentations rather than on specific diseases.Sessions will include discussions by clinicians and pathologists and will include clinical cases.A set of slides will accompany the syllabus, which will be given to all registrants and sent to preregistrants 1 to 2 mo before the course.The course will also include some overview.Two sessions will be held on Saturday, November 2, one dealing with cholestatic syndromes and one with chronic hepatitis.Session I will focus on the differential diagnosis of chronic cholestatic syndromes such as primary biliary cirrhosis and sclerosing cholangitis, acute cholestatic syndromes such as postoperative jaundice and jaundice of sepsis and pediatric cholestatic syndromes such as biliary atresia and neonatal hepatitis.
JAMAICA-GINGER DRINKERS' AMBLYOPIA.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal