tbuckley/cabot-search huggingface dataset:
Cost containment and the physician
Authors: M. Angell
Journal: JAMA (1985)

The rapid rise in health care costs is receiving a good deal of attention these days. Proposed responses include the deliberate rationing of expensive medical technologies, such as organ transplantation, and a redirection of our efforts toward preventive care. Although preventive care may improve our health, it cannot be assumed to reduce medical costs, since a later death may be as expensive as an earlier one. I suggest that a major and rapidly growing component of medical costs stems from the widespread application of tests and procedures when they are of no demonstrated benefit and may even be harmful. Identifying and curtailing such unnecessary medical care, rather than rationing beneficial technologies, should be the thrust of cost-containment efforts. Fee schedules should be revised so that they neither encourage nor discourage the use of tests and procedures; we should undertake systematic studies to assess technologies and practices; and we should make every effort to discourage the practice of defensive medicine. The involvement of physicians in rationing is not only premature; it is also inconsistent with our role as advocates for the health of our patients. (<i>JAMA</i>1985;254:1203-1207)
Coexistence of Rheumatic Heart Disease and Sickle Cell Anemia
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CD: ADAM Interactive Anatomy The Anatomy Project
Authors: A. Hunter
Journal: BMJ (2000)

ADAM Software Harcourt Brace, £1091.49 ISBN 1 572 45099 1 Debra Hastings-Nield Parthenon Publishing, each CD £79.90 (free demonstration CD) ISBN 185070 9106 Rating: ![Graphic][1]</img>![Graphic][2]</img>![Graphic][3]</img>![Graphic][4]</img>![Graphic][5]</img> The teaching of anatomy is undergoing something of a revolution. Increasing numbers of medical schools are giving up traditional methods, such as dissection, in favour of student directed or problem based learning. Students are given access to computers as a major source of information, and are given multimedia packages when once they would have been given a cadaver and a scalpel. There is also a heavy demand for anatomical multimedia from postgraduates. This is fuelled partly by a shift in the surgical fellowship exams and a heavy reliance on distance learning, but also by a reduction in anatomy teaching in the undergraduate curriculum. The market for anatomical CD Roms is therefore booming. ADAM Interactive Anatomy provides … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif [3]: /embed/inline-graphic-3.gif [4]: /embed/inline-graphic-4.gif [5]: /embed/inline-graphic-5.gif
Uvulazation
Authors: Robert Fishbein
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Retroperitoneal Rupture of the Duodenum Due to Blunt Non-Penetrating Abdominal Trauma
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Norman Lawrence
Authors: U. Lawrence
Journal: BMJ (2013)

<b>Background:</b> Despite having similar mild-moderate airflow obstruction some individuals report a greater burden of symptoms and exacerbations. <b>Aims:</b> Explore factors associated with self-reported symptom severity and exacerbation history in mild-moderate COPD patients. <b>Methods:</b> 107 individuals with COPD were recruited from primary care in Leicestershire, UK. COPD symptoms were assessed using the COPD Assessment Test (CAT) and modified Medical Research Council (mMRC) scores. One-year exacerbation history was self-reported. The incremental shuttle walk test (ISWT) assessed exercise capacity. Moderate-to-vigorous physical activity (MVPA) and sedentary time were assessed using wrist-worn accelerometry with average activity intensity provided by vector magnitude counts per minute (VMCPM). Patients were grouped pragmatically by symptom severity. <b>Results:</b> Patients reporting CAT &gt;20 or mMRC ≥2 were more sedentary than those reporting CAT 0-10 or mMRC 0 (Δ69-81min/day). Patients reporting ≥2 exacerbations accrued less MVPA (Δ20min/day) than patients reporting 0 exacerbations. Multiple linear regression (age, gender, smoking and employment) showed that ISWT (B=-0.016±0.005, p=0.004) and years living with COPD (B=0.319±0.122, p=0.011) were associated with CAT score. ISWT (B=-0.002±0.001, p&lt;0.001) and VMCPM (B=0.0001±0.0000, p=0.011) were associated with mMRC grade. MVPA was associated with previously reported exacerbations (B=-0.034±0.012, p=0.005). <b>Conclusion:</b> Individuals with mild-moderate COPD reporting severe symptoms were less physically active, more sedentary and had worse exercise capacity but the magnitudes of these associations were weak.
Benign
Authors: Jack Coulehan
Journal: Annals of Internal Medicine (2009)

Ad Libitum1 December 2009BenignJack Coulehan, MD, MPHJack Coulehan, MD, MPHFrom Setauket, NY 11733.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-151-11-200912010-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail The snow I shoveledthe day before yesterdaysheared and pummeledthe neck of my nerve,the pincers of timeproclaiming they'e readya few years earlierthan I desired—but at leastnot a malignantflower of the brainblooming near season's end,nor multiple sclerosis,for mine is singular,thorny, deep, and dead.Words are never the clincherswe desire in describingthe jowls of pain. Reliefwill come when that ball peenhammered nerve, a snakeon a rock in the sun,molts its skin. Ageoffers hundredsof sinkholes to fall in.Jack Coulehan, MD, MPHSetauket, NY 11733 Author, Article, and Disclosure InformationAffiliations: From Setauket, NY 11733.Current Author Address: Jack Coulehan, MD, MPH, 4 Townsend Court, Setauker, NY 11733. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 December 2009Volume 151, Issue 11Page: 822KeywordsBrainFallsMultiple sclerosisNerves ePublished: 1 December 2009 Issue Published: 1 December 2009 Copyright & PermissionsCopyright © 2009 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Free Papers
Authors: N. Kermarrec, A. Karim, S. Beloucif, D. Payen, R. Waurick, M. Booke, H. G. Bone, J. Meyer, Th. Prien, H. Van Aken, P. Datta, S. Magder, A. Rosselet, L. Liaudet, M. Markert, C. Perret, F. Feihl, J. C. Preiser, D. De Backer, F. Debelle, B. Vray, R. J. Kahn, J. L. Vincent
Journal: Intensive Care Medicine (1996)
Handbook of experimental and therapeutic diets. State University of Iowa Hospital Nutrition Department.
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Embolectomy of Middle Cerebral Artery
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PWE-187 The helicobacter eradication aspirin trial (Heat): a large simple randomised controlled trial using novel methodology in primary care
Authors: JS Dumbleton, A Avery, C Coupland, FDR Hobbs, D Kendrick, MV Moore, C Morris, GP Rubin, MD Smith, CJ Hawkey
Journal: Gut (2015)

<h3>Introduction</h3> Clinical trials measuring the effect of an intervention on clinical outcomes are more influential than those investigating surrogate measures but are costly. We developed methods to reduce costs substantially by using existing data in primary and secondary care systems, to ask whether <i>Helicobacter pylori</i>eradication would reduce the incidence of hospitalisation for ulcer bleeding in aspirin users. <h3>Method</h3> The <i>Helicobacter</i>Eradication Aspirin Trial (HEAT) is a HTA-funded, CRN-supported, double-blind placebo controlled randomised trial of the effects of <i>H. pylori</i>eradication on subsequent ulcer bleeding in infected individuals taking aspirin daily, conducted in practices across the whole of England, Wales and Northern Ireland. A bespoke web-based trial management system developed for the trial (and housed within the secure NHS N3 Data Network) communicates directly with the HEAT Toolkit software downloaded at participating practices, which issues MIQUEST queries searching entry criteria (≥60 years, on chronic aspirin ≤325mg daily, not on anti-ulcer therapy or non-steroidal anti-inflammatory drugs) for GP review of eligibility. Trial participation is invited using a highly secure automated on-line mail management system that ensures patients receive an invitation within 48 h. Interested patients are seen once for consent and breath testing. Those with a positive test are randomised to eradication treatment (lansoprazole, clarithromycin, metronidazole) or placebo with drug sent by post. Events are tracked by upload of accumulating information in the GP database, patient contact, review of national Hospital Episode Statistics and ONS data. <h3>Results</h3> HEAT is the largest CRN CTIMP trial, with 105,276 invitation letters sent from 772 practices, 20,509 volunteers, and 2,847 <i>H. pylori</i>positive patients randomised to active or placebo treatment after 2.5 years of recruitment. 178 practices have performed their first follow-up MIQUEST search to identify 21 potential endpoints to date. <h3>Conclusion</h3> HEAT is important medically, because aspirin is so widely used, and methodologically, as a successful trial would show that large-scale studies of important clinical outcomes can be conducted at a fraction of the cost of those conducted by industry, which in turn will help to ensure that trials of primarily medical rather than commercial interest can be conducted successfully in the UK. <h3>Disclosure of interest</h3> None Declared.
Triple Hernia
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Assessing the clinical significance of real-time quality of life (QOL) data in cancer patients treated with radiation therapy.
Authors: M. Y. Halyard, A. Tan, M. D. Callister, J. B. Ashman, S. A. Vora, W. Wong, S. E. Schild, P. J. Atherton, J. A. Sloan
Journal: Journal of Clinical Oncology (2010)

9107 Background: The importance of patient-reported outcomes (PRO) and QOL domains have been shown to be prognostic in clinical trials, but few applications exist in practice. This study is being performed to determine if real-time patient-reported QOL can be collected and effectively used by the radiation therapy (RT) team in patient care. Methods: Atwo-arm, longitudinal design study with 132 head and neck, GI, and lung cancer patients receiving curative RT is ongoing. Data collection occurs in two phases: control and active intervention groups, 66 patients each. At baseline and weeks 1, 3, 5 and last week of RT, patients complete a web based, electronic Linear Analogue Self Assessment (LASA) tool while care providers complete a Global Satisfaction Score questionnaire. The Interpersonal Patient-Provider Relationship Scale (IPPR), and the Was it Worth It (WIWI) questionnaires are completed during the last week of RT. Control phase data collection is complete. We present the QOL data from the control phase and the strategy for implementation of real-time electronic PRO data collection. Results: Results from the control group phase revealed thatof 66 patients 92.4%, 87.9%, 77.3%, 80.3%, 72.8% had LASA data at baseline, weeks 1, 3, 5 and last week respectively; 74.2% had IPPR and 72.8% had WIWI data. Decreased LASA scores in the realms of overall QOL (p-value=0.0022), mental well being (p-value=0.0091), physical well being (p-value=0.0257), and social activity level (p-value=0.0118) occurred during RT. There was an increased LASA pain during RT (p-value=0.0498). 83% of patients felt that it was worth while to participate in this study and 96% would participate in this study again or recommend others to participate. 90% of physicians/nurse/nurse practitioners are satisfied/highly satisfied with the communication with their patient during the visit. Conclusions: This study represented the first reported use of electronic collection of real-time QOL data during weekly RT. We have demonstrated that real-time collection of QOL data is feasible, acceptable, and provides patient reported information felt useful to the clinical team. No significant financial relationships to disclose.
Signal Transducer and Activator of Transcription (STAT)-3 Activates Nuclear Factor (NF)-κB in Primary Myelofibrosis (PMF) Bone Marrow Cells
Authors: Srdana Grgurevic, Srdan Verstovsek, Zhiming Liu, Taghi Manshouri, David Harris, Ping Li, Hagop M. Kantarjian, Zeev Estrov
Journal: Blood (2011)
Probucol (Lorelco) in treatment of hyperlipemia
Authors: B. F. Murphy
Journal: JAMA (1977)

The chemical structure of probucol differs from that of other hypolipemic agents, and its mechanism of action is unknown. This agent lowers elevated serum cholesterol (and low-density lipoprotein) levels and appears to be effective when used as an adjunct to a low-cholesterol, low-saturated-fat diet for treatment of type lla hyperlipoproteinemia in adults; however, it is less effective than cholestyramine resin in patients with familial type lla disorder. Although probucol has no consistent effect on elevated triglyceride levels, it may be useful as an adjunct to other drugs that lower these concentrations in patients with types llb, III, and IV hyperlipoproteinemia when hypercholesterolemia persists. Probucol is generally well tolerated. (<i>JAMA</i>238:2537-2538, 1977)
The Gamma Globulins
Authors: Fred S. Rosen, Charles A. Janeway
Journal: New England Journal of Medicine (1966)

Secondary AgammaglobulinemiaSignificant depressions of serum gamma globulins are usually found in the serums of patients with protein-losing enteropathy, exfoliative dermatitides and the nephrotic syndrome or occasionally with severe malnutrition. Decreased serum gamma globulins due to hypercatabolic states have been reported.368 Defective synthesis of gamma globulin frequently accompanies neoplasm of the lymphoid system, particularly reticulum-cell sarcoma, lymphosarcoma, Hodgkin's disease and chronic lymphocytic leukemia. Such patients have undue susceptibility to infection, but the reasons for this may be more complex owing to their basic pathologic processes. Patients with hypergammaglobulinemia due to M-component disease, such as multiple myeloma and Waldenström's disease, may . . .
Bipolar Disorder
Authors: R.H. Belmaker
Journal: New England Journal of Medicine (2004)

Bipolar disorder, one of the most distinct syndromes in psychiatry, has been described in numerous cultures throughout history. The unique hallmark of the illness is mania, which is characterized by elevated mood or euphoria, overactivity with a lack of need for sleep, and overoptimism that impairs judgment. Periods of depression are also a feature of the disorder.
Association of blood pressure and PCB level in yusho patients.
Authors: K Akagi, M Okumura
Journal: Environmental Health Perspectives (1985)

Correlations of blood polychlorinated biphenyl (PCB) levels or PCB patterns and blood pressures were studied in 59 patients with yusho (PCB poisoning) above 40 years old. In spite of the passage of 13 years from the onset, 52.5% of these patients still have PCB levels higher than the range found in the general population. The frequency of hypertension in the patients was 16.9%, a value similar to that expected on the basis of the rate for a population of the same age and sex compositions. As an independent variable, the blood pressure of patients was not associated with blood PCB levels and PCB patterns. No PCB blood pressure association was confirmed in 20 patients with PCB levels persistently higher than 5 ppb for 9 years. On the other hand, age, obesity and habitual alcohol intake, known influencing factors for hypertension, tended to be positively associated with elevated blood pressure in these yusho patients.