tbuckley/cabot-search huggingface dataset:
A Manual of Bacteriology, Medical and Applied.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE INTERPRETATION OF EDEMA
Journal: JAMA (1925)

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Abstract P127: Gender and Fitness Status Influence Age-related Decline in Peak Heart Rate Achievement: Insight From the FIT Cohort
Authors: Haitham Ahmed, Di Zhao, Eliseo Guallar, Michael J Blaha, Clinton A Brawner, Steven J Keteyian, Mouaz H Al-Mallah, Erin D Michos
Journal: Circulation (2016)

Background: The declines in peak heart rate (HR) and fitness level with age are related; however, whether this association differs based on gender is not well appreciated. In a large cross-sectional cohort of women and men referred for a clinically indicated exercise treadmill test (ETT), we set out to determine whether the decrease in peak HR by age varied by gender (and fitness) in the Henry Ford Exercise Testing (FIT) project. Methods: We analyzed data on 38,196 apparently-healthy patients aged 18-96 [mean age 51 ± 12 yrs, 25% black, 48% women] who completed an ETT. Those with history of coronary heart disease, congestive heart failure, diabetes on medications, atrial fibrillation or flutter, or taking AV nodal blocking medications were excluded. Being “fit” was defined as achieving ≥ the median MET level for each sex/age-decile group. Peak HR vs age was plotted, and regression lines were used to determine the intercept and slope for each group. Results: Men had higher peak HR than women but with a greater decline over time; the respective intercepts and slopes for peak HR estimates were 202.9 and 0.90 for men and 197.3 and 0.80 for women, (p-interaction = 0.023). Fit people also started out with higher peak HR but approached unfit people at higher age groups; respective intercept and slope by fitness status were 203.0 and 0.87 for fit and 194.7 and 0.83 for unfit (p-interaction &lt;0.001). Separate regression lines were generated for categories of fit men/unfit men, fit women/unfit women ( Figure ). Fit and unfit men had similar declines in peak HR with increasing age (slope=0.92); whereas fit women (slope=0.81) had a slightly greater decline in peak HR with increasing age than unfit women (slope=0.73). However, peak absolute HR for fit people still remains higher than for unfit people even into elderly ages. Conclusion: In this cross-sectional cohort of patients referred for a clinical ETT, we found that the age-related decline in peak HR is influenced by both gender and fitness status.
Editorial: Clinical diagnosis of cutaneous malignant melanoma
Authors: W. H. Clark
Journal: JAMA (1976)

Proper management of the cutaneous pigmented lesion is of concern to virtually every clinician. The initial step, and one of the most important steps, in the management of pigmented lesions is clinical diagnosis. Paramount among the various possible diagnoses, because of its potential life threat, is malignant melanoma. Probably the majority of physicians are unaware that primary cutaneous malignant melanomas, even in their initial stages of development, usually have a distinctive appearance that should result in considerable accuracy in clinical diagnosis. Proper clinical diagnosis in the early developmental stages of the various forms of cutaneous malignant melanoma should result in a series of diagnostic and therapeutic procedures that should result in a high cure rate for this disease (a disease once regarded as one of the more formidable neoplasms to affect man, a reputation undeserved in the light of recent studies<sup>1,2</sup>). Kopf et al, in a recent article,<sup>3</sup>
The Enigma of the Human Voice
Journal: JAMA (1963)

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Pielografia ASCENDENTE e PIELOGFRAFIA discendente CON SPECIALE RIGUARDO ALLA nefropieloureterografia PER VIA ENDOVENOSA.
Journal: JAMA (1931)

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Fiction
Journal: JAMA (2002)

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Pediatrics
Authors: Gilbert B. Forbes
Journal: JAMA (1978)

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Formula Term.
Journal: JAMA (1963)

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Update on Vaccine-Derived Polioviruses — Worldwide, January 2016–June 2017
Authors: Jaume Jorba, Ousmane M. Diop, Jane Iber, Elizabeth Henderson, Roland W. Sutter, Steven G.F. Wassilak, Cara C. Burns
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

In 1988, the World Health Assembly launched the Global Polio Eradication Initiative (GPEI) (1). Among the three wild poliovirus (WPV) serotypes, only type 1 (WPV1) has been detected since 2012. Since 2014, detection of WPV1 has been limited to three countries, with 37 cases in 2016 and 11 cases in 2017 as of September 27. The >99.99% decline worldwide in polio cases since the launch of the GPEI is attributable to the extensive use of the live, attenuated oral poliovirus vaccine (OPV) in mass vaccination campaigns and comprehensive national routine immunization programs. Despite its well-established safety record, OPV use can be associated with rare emergence of genetically divergent vaccine-derived polioviruses (VDPVs) whose genetic drift from the parental OPV strains indicates prolonged replication or circulation (2). VDPVs can also emerge among persons with primary immunodeficiencies (PIDs). Immunodeficiency-associated VDPVs (iVDPVs) can replicate for years in some persons with PIDs. In addition, circulating vaccine-derived polioviruses (cVDPVs) can emerge very rarely among immunologically normal vaccine recipients and their contacts in areas with inadequate OPV coverage and can cause outbreaks of paralytic polio. This report updates previous summaries regarding VDPVs (3). During January 2016-June 2017, new cVDPV outbreaks were identified, including two in the Democratic Republic of the Congo (DRC) (eight cases), and another in Syria (35 cases), whereas the circulation of cVDPV type 2 (cVDPV2) in Nigeria resulted in cVDPV2 detection linked to a previous emergence. The last confirmed case from the 2015-2016 cVDPV type 1 (cVDPV1) outbreak in Laos occurred in January 2016. Fourteen newly identified persons in 10 countries were found to excrete iVDPVs, and three previously reported patients in the United Kingdom and Iran (3) were still excreting type 2 iVDPV (iVDPV2) during the reporting period. Ambiguous VDPVs (aVDPVs), isolates that cannot be classified definitively, were found among immunocompetent persons and environmental samples in 10 countries. Cessation of all OPV use after certification of polio eradication will eliminate the risk for new VDPV infections.
The City.
Journal: JAMA (1926)

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Les syphilis viscérales tardives.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE DETERMINATION OF SEX.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Radiation therapy for "wet" type macular degeneration shows promise in early trials
Authors: A. A. Skolnick
Journal: JAMA (1997)

EARLY clinical trials of an experimental treatment for the leading cause of blindness in developed countries have yielded encouraging although not yet convincing results. In the trials, a majority of patients with age-related macular degeneration of the "wet" type, who received lowdose external beam radiation to halt the proliferation of blood vessels beneath their retinas, experienced stabilized or improved vision. However, some ophthalmologists and others are not yet convinced that the improvement and stabilization of vision reported was a result of the treatment. Because the vision of patients with macular degeneration often stabilizes or improves without treatment, at least for a while, randomized controlled trials are necessary, they say, before this therapy can be considered effective. <h3>2 Types of Disorder</h3> There are 2 kinds of age-related macular degeneration, and the causes of both are unknown. The "wet" type is marked by a proliferation of blood vessels beneath the retina that
The Gulstonian Lectures on Pulmonary Cavities: Their Origin, Growth, and Repair
Authors: W. Ewart
Journal: BMJ (1882)

its own definite and well marked pathological processes, but in simu- lating others, from the stupor of typhus, the collapse of cholera, the high temperature of insolation, the sickness of an irritant poison, to the convulsions of epilepsy or of dentition, which may occur in the per- nicious forms.It induces anaemia and general cachexia, with structnral changes in the liver, spleen, or other viscera.Neuralgia, asthma, and various other symptoms of disturbed innervation and sanguification; and, as I have before said, appears to be in close etiological relation with dysentery, cholera, diarrhoea, beri-beri, hydrocele, ele- phantiasis, bronchocele, and hepatic disease.Whatever its naturemay be, the action ofmalariaon the human economy is very striking; it affects the central nervous system, causing disturbance of vaso-motor action, paroxysms of fever, and congestion of the abdo- minal viscera, which become periodic in recurrence, or pass on to struc- tural changes in the liver and spleen, or intestinal mucous membrane.No one can have resided long in a malarious climate, like Assam, without observing the cachectic, deteriorated aspect of the people, who, although they may never have had a single attack of fever, and do not feel ill, and would resent being told so, are yet victims to the in- sidious action of the poison, and present evidences of anzemia, degenerate tissues, and chronic visceral disease.In my next lecture, I shall describe intermittent fever as it occurs in India.
Apoptosis and hepatobiliary disease*1
Authors: T PATEL
Journal: Hepatology (1995)

In this review we have attempted to summarize recent information on the role of apoptosis in normal liver biology and as a pathophysiological mechanism of cell death during hepatobiliary disease. Apoptosis is an important mechanism of cell injury and death in pathogenic settings as diverse as cell-mediated cytotoxicity, drug and chemical toxicity, carcinogenesis, viral disease, and autoimmune disease. Several factors account for the widespread attention and flurry of investigative activity into the phenomenon of apoptosis including the following: (1) realization that apoptosis is an important component of the behavior of all cells; (2) increasing evidence supporting a role for apoptotic cell death in diverse pathological settings; (3) elucidation of the biochemical pathways and insight into the genetic and molecular regulation of the process; and (4) development of new techniques to identify cells undergoing apoptosis. Recognition of the importance and role of apoptosis in hepatobiliary disease should stimulate interest and promote basic research toward understanding the mechanisms involved. Subsequent investigation into defining the cellular regulatory mechanisms and biochemical processes involved will be fertile ground for future research that may ultimately lead to novel therapeutic approaches for autoimmune diseases, malignancies, and viral disease.