tbuckley/cabot-search huggingface dataset:
Heredity and Disease
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
High-dose penicillin therapy and pneumococcal pneumonia
Authors: A. Brewin
Journal: JAMA (1974)

Patients with pneumococcal pneumonia were studied to determine if severely ill patients benefit more from massive dosages of penicillin compared with moderate dosages. Severity of illness and response to treatment were evaluated, and sputum was monitored for pathogens. Twenty-two of the 59 patients assigned to receive 20 million units of penicillin daily and 19 of the 64 assigned to receive 1,200,000 units of penicillin G procaine daily were considered severely ill. In the high-dosage group, there were five deaths, three patients with superinfections, and 22 with pathogen colonizations, and in the moderate-dosage group, six deaths, two patients with superinfections and eight with pathogen colonizations. There was no significant difference (P &lt;.75) in outcome between the groups. We conclude that there is no advantage in treating patients with more than 1,200,000 units of penicillin G procaine daily. (<i>JAMA</i>230:409-413, 1974)
Tumor Promotion Studies in Rat Tracheal Epithelium
Authors: Vernon E. Steele, Douglas C. Topping, S. Balakrishna Pai
Journal: Environmental Health Perspectives (1983)

The tracheal epithelium of the Fischer 344 rat is histologically very similar to that of the human bronchus. Also, carcinomas of tracheal origin in F-344 rats are similar in morphology to human bronchogenic carcinomas. Tumor promotion in rat tracheal epithelium was studied by using two model systems. The first is a heterotopic transplant system in which rat tracheas are implanted subcutaneously on the backs of isogenic recipents. In the first system, the epithelium was topically exposed to pellets containing 7,12-dimethylbenz(a)anthracene (DMBA), used as the initiating agent, followed by pellets containing the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA), the promoting agent. After 98 weeks, a three- to fourfold increase in the percentage of tracheas having malignant tumors was seen in tracheal transplants receiving both DMBA and TPA compared to DMBA alone. Exposure of the tracheal grafts to TPA alone resulted in epithelial hyperplasia and inflammation, but no dysplastic lesions. The second system is an organ culture-cell culture system in which small pieces of trachea are grown in organ culture, then epithelial cells are grown from these pieces as primary cell cultures. The organ cultures were exposed to the direct alkylating agent, N-methyl-N′-nitro-N -nitrosoguanidine (MNNG) used as the initiator, then multiple short exposures to TPA were used to promote. Primary cell cultures and cell lines were then established from these explants. After 52 weeks, a five-fold increase in the percentage of explants producing tumorigenic cell lines was observed when MNNG + TPA-exposed explants were compared to MNNG-exposed explants. Tracheal explants exposed to TPA alone produced many cell lines but none tested were tumorigenic. These two systems provide a means to study tumor promotion in respiratory epithelium. The evidence more importantly suggests that airborne promoting substances may play a key role in the development of bronchogenic carcinoma.
HIV/HCV co-infected subjects show better thrombocytopenia improvement after sustained virologic response achievement than HCV mono-infected cirrhotics. Data from the hepaiCONA and PITER cohorts.
Authors: Roberto Rossotti, Alessandro Tavelli, Maria Giovanna Quaranta, Francesca Bai, Luigina Ferrigno, Antonella Cingolani, Francesco Barbaro, Marcello Dallio, Massimo Puoti, Martina Loi, Emanuela Zappulo, Antonella d’Arminio Monforte
Journal: Journal of Hepatology (2020)
PUERPERAL INFECTION IN PRIVATE PRACTICE.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Factors affecting late mortality from heart disease after treatment of Hodgkin's disease
Authors: S. L. Hancock
Journal: JAMA (1993)

<h3>Objective.</h3> —To assess the risk of death from heart disease after Hodgkin's disease therapy. <h3>Design.</h3> —Retrospective study comparing treated patients with a matched general population. <h3>Setting.</h3> —Referral center. <h3>Patients.</h3> —A total of 2232 consecutive Hodgkin's disease patients treated from 1960 through 1991. Follow-up averaged 9.5 years. <h3>Main Outcome Measures.</h3> —Relative risks (RRs), the ratio of the observed to the expected cases with 95% confidence intervals (Cls), χ tests for trends, and Kaplan-Meier actuarial risks. <h3>Results.</h3> —Of the 2232 patients, 88 (3.9%) died of heart disease, 55 from acute myocardial infarction and 33 from other cardiac diseases, including congestive heart failure, radiation pericarditis or pancarditis, cardiomyopathy, or valvular heart disease. The RR for cardiac death was 3.1 (Cl, 2.4 to 3.7). Mediastinal radiation of 30 Gy or less (n=385 patients) did not increase risk; above 30 Gy (n=1830), RR was 3.5 (Cl, 2.7 to 4.3). Blocking to limit cardiac exposure reduced the RR for other cardiac diseases from 5.3 (Cl, 3.1 to 7.5) to 1.4 (Cl, 0.6 to 2.9), but not acute myocardial infarction (RR, 3.7 vs 3.4). The RRs increased with duration after treatment (trend in acute myocardial infarction,<i>P</i>=.02; in other cardiac diseases,<i>P</i>=.004). The RR for acute myocardial infarction was highest after irradiation before 20 years of age and decreased with increasing age at treatment (<i>P</i>&lt;.0001 for trend). <h3>Conclusions.</h3> —Mediastinal irradiation for Hodgkin's disease increases the risk of subsequent death from heart disease. Risk increased with high mediastinal doses, minimal protective cardiac blocking, young age at irradiation, and increasing duration of follow-up. (JAMA. 1993:270:1949-1955)
Pentazocine-induced fibrous myopathy
Authors: S. J. Oh
Journal: JAMA (1975)

Fibrous myopathy was found in three patients who had taken pentazocine intramuscularly for years. Fibrotic induration in the quadriceps and deltoid muscles,<i>the considerable limitation of motion due to the fibrotic muscle contracture, and the minimal weakness of involved muscles</i>are the most characteristic findings in this condition. Results of animal experiments support the close relationship between myopathy and pentazocine. This serious complication emphasizes more judicious use of pentazocine. (<i>JAMA</i>231:271-273, 1975)
ERCP Topics
Authors: G. G. Ginsberg
Journal: Endoscopy (2005)

Clinical investigations aimed at enhancing efficacy, improving safety, and expanding applications of endoscopic retrograde cholangiopancreatography (ERCP) remain vital. The most compelling themes address new techniques and new technologies applied to new and old problems. While the development of endoscopic ultrasonography (EUS) and other imaging technologies has diminished the role of ERCP as a diagnostic tool, the growth in orthotopic liver transplantation and gastric bypass surgery have created new therapeutic applications and challenges. This review covers some of the highlights from this year’s Digestive Disease Week.
Erythroblastosis Fetalis
Authors: Fred H. Allen, Louis K. Diamond
Journal: New England Journal of Medicine (1957)

Technic of Exchange TransfusionAlthough we do not intend to discuss technic in detail, there are a few improvements over the previously published method that are worth mentioning. The first is the plastic infant-feeding tube (Fig. 3), which has a closed, smoothly rounded tip with holes on the sides, and a plastic connector at the proximal end that fits a plain Luer male connector, such as is found on the B-D L/S three-way stopcock. These tubes can be autoclaved if packed carefully, but it is probably better to use a new one for each transfusion, since they are sold individually . . .
Domestic Abstracts
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Intravenous Antibiotics and Genitourinary Obstruction
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
From the Centers for Disease Control and Prevention. Technical guidance on HIV counseling
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"BONDS NOT NECESSARY FOR PHYSICIANS"
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Outpatient Surgery
Authors: Yeu-Tsu N. Lee
Journal: JAMA (1974)

This book aims to help surgeons and their assistants deliver more effective care to all who come to our medical facilities, especially the outpatient clinics, emergency room, and overnight ward. Twenty-nine chapters are contributed by 26 full-time and voluntary faculty members of the University of Colorado. Besides general topics such as organization, anesthesia, infections, pain, metabolism, and endocrinology, the presentation emphasizes organ systems and subspecialities of surgery. The chapter on trauma describes the overall management of major and minor trauma (including techniques of knot-tying), while discussion of transplantation covers aspects of preoperative selection of recipients and their postoperative management. The chapter on heart and cardiac surgery gives the most balanced coverage. Other than cardiac trauma and pacemaker problems, it teaches the physician treating outpatients how to decide on the correct time for operations, such as complete preoperative evaluation and assessing the risk of operation for the patient. After surgery, drug
Metric Systems
Authors: G. G. Liddle
Journal: JAMA (1971)

<h3>To the Editor.—</h3> Now that The Journal is going metric, I am eating my heart out in grams. Wondering how anyone can demonstrate that "torr" is more understandable than mm Hg, Barry M. Austen of Cincinnati wrote in<i>Science</i>that all this useless arbitrary pedantry torr his heart out. "It hertz so much it gave me a fever," he wrote, which he will always measure in degrees centigrade, and no Kelvin or Celsius for him. But what bothers me is that your writers did not explain that the meter, which was originally supposed to 1/10 millionth part of the quadrant of the earth, did not come out right, because the 18th century precision instruments goofed off. And what about that platinum bar, which expands and contracts? The worst part about this metric business is that it does not get down to basics. When Eve ate an apple, and Adam discovered
Abstract 3300: The Impacts of Coronary Artery Calcium on the Diagnostic Accuracy in Detecting Stenoses Using 64-slice Spiral Computed Tomography
Authors: Mingming Gao, Hao Sun, Zhan-Hong Ma, Lei Zhang, Xin-Chun Yang, Yong-Li Xue
Journal: Circulation (2007)

Objective: To investigate the diagnostic accuracy of 64-slice spiral computed tomography (MSCT) to coronary artery lesions, and to analyze the impacts of coronary artery calcium to diagnostic accuracy in detecting coronary artery lesions. Methods: Sixty patients underwent 64-slice spiral CT and conventional coronary angiography(CCA). Calciumscoring was estimated with plain scans, while 2D and 3D reconstruction were done with enhanced scans. The diagnostic accuracy of MSCT to detect significant lesions was evaluated regarding quantitative coronary angiography (QCA) as the standard of reference, and to analyze the impacts of coronary artery calcium on diagnostic accuracy. Results: A total of 797 segments can be diagnosed. The overall sensitivity, specificity, positive predictive value and negative predictive value of 64-slice spiral CT were 96%(174 of 182), 98%(601 of 615), 93%(174 of 188), and 99%(601 of 609) respectively. Within a total of 591 segments with calcium score =0 (Agatston score), the specificity was 100%(498 of 499)and the positive predictive value was 99%(86 of 87). However, 49 segments had a calcium score ≥100, with specificity at 63%(12 of 19)and positive predictive value at 81%(30 of 37). Conclusions: In patients with none or moderate coronary calcification, the 64-slice spiral CT coronary angiography allows for the reliable detection of coronary artery stenoses. Severe coronary artery calcification may still degrade the diagnostic specificity and positive predictive value of 64-slice spiral CT.
Disease and the Man.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The press embargo: friend or foe?
Authors: J. Stacey
Journal: JAMA (1985)

In the history of journalism, press embargoes are remembered more in the breach than in compliance. A press embargo represents information offered reporters prior to the date and time of official release as "news." It is a system that gives each reporter an equal break on the news, along with time to develop the story through appropriate interviews and other research. The system may have been in place from time immemorial. Certainly, that is the impression of Curtis MacDougall, emeritus professor of journalism, Northwestern University. In conversation, he suggested that the system might go back to George Washington and the Revolutionary War. "They've been around ever since I started out in journalism 50 years ago," he said. Professor Charles-Gene McDaniel of Roosevelt University says that the system might have begun with the George Creel Committee on Public Information, created by President Wilson one week after the United States entered World
Preferences of Patients With Advanced Cancer for Hospice Care
Authors: R. M. Navari
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
BUENOS AIRES
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal