tbuckley/cabot-search huggingface dataset:
An untoward reaction to accidental ingestion of LSD in a 5-year-old girl
Authors: D. H. Milman
Journal: JAMA (1967)

A 5-year-old girl with an apparently normal premorbid personality and adjustment became acutely psychotic following a single accidental ingestion of 100μg of d-lysergic acid diethylamide (LSD), with agitation, panic, depression and flattening of affect, disorientation, feelings of depersonalization, distortion of body image, and depression of intellectual functioning. In addition she displayed evidences of organic brain dysfunction: impaired visual-motor and visual-perceptual functions, and abnormality of the electroencephalogram. Within days the most florid evidences of disturbance had disappeared but the thinking disorder, distortion of body image, and depression of intelligence quotient persisted for several months. At the end of five months the only residua were the abnormal EEG and disorganization of visual-motor functions. At the end of nine months only the visualmotor functions remained impaired.
Anesthesiology, Philadelphia
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Clinical challenges in pediatric renal transplantation. Proceedings of 2nd North American Pediatric Renal Transplantation Cooperative Study (NAPRTCS) Workshop. Boston, April 17-18, 1991.
Journal: Journal of the American Society of Nephrology (1992)

Journal of the American Society of Nephrology : JASN 2(12):p S213, June 1992. | DOI: 10.1681/ASN.V212s213
Correction
Journal: BMJ (1966)

We publish below a selection of questions and answers of general interest.Blood Levels of Tetracycline Q.-Does tetracycline given in dragees in doses of 500 mg. at 12-hourly intervals pro- vide adequate blood levels throughout the day, and is such a dosage effective clinically ?A.-Kunin, Dornbush, and Finland' cal- culated the half-life of chlortetracycline to be 5.6 hours, tetracycline 8.5 hours, and oxy-
About the Cover...
Journal: JAMA (1975)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Are reflectance meters necessary for home blood glucose monitoring?
Authors: S D Ferguson, I A Hughes
Journal: BMJ (1980)

One explanation of these anomalies is that talc may be acting as a particulate adjuvant, promoting cell-mediated hypersensitivity reactions to polysaccharide antigens of starch in susceptible individuals.For these reasons we would support efforts to eliminate talc, which although not directly pathogenic in low con- centration, may facilitate cell-mediated re- action to other agents on the surface of surgical gloves.
Abstracts of the 21st Annual Northeast Regional Scientific Meeting, Greater New York and New England Chapters of the Society of Nuclear Medicine, Oct 26–28, 2008, Stamford, Connecticut
Journal: Clinical Nuclear Medicine (2009)

Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy. Subscribe to eTOC Secondary Logo Journal Logo All Articles Images Videos Podcasts Blogs Advanced Search Toggle navigation Subscribe Register Login Articles & Issues Current IssuePrevious IssuesPublished Online First Collections ACNM MeetingsCMECommunication in OrganizationCOVID-19Feedback and RewardsFrom the American College of Nuclear MedicineHighly Cited and Frequently Read ArticlesPlanning and Conducting Meetings EffectivelyQuality and Safety in Health CareRecruitment of New PhysiciansTips for Giving a Memorable PresentationTips for LeadersTips for Physicians in Getting the Right Job ACNM ArticlesACNM Website For Authors Submit a ManuscriptInformation for AuthorsLanguage Editing ServicesAuthor Permissions Journal Info About the JournalEditorial BoardAdvertisingOpen AccessSubscription ServicesReprintsRights and Permissions All Articles Images Videos Podcasts Blogs Advanced Search
Results of the Prospective Evaluation of Radial Keratotomy (PERK) Study 4 years after surgery for myopia. Perk Study Group
Authors: G. O. Waring
Journal: JAMA (1990)

The Prospective Evaluation of Radial Keratotomy Study is a nine-center clinical trial of a surgical technique to reduce simple myopia by making incisions in the cornea. There were 435 patients (one eye per patient is reported) enrolled in the study with a 91% follow-up rate at 4 years after surgery. After surgery, uncorrected visual acuity was 20/40 or better in 76% of eyes. Fifty-five percent of the eyes had a refractive error within ± 1.00 diopter; 28% were undercorrected, and 17% were overcorrected by more than 1.00 D. The width of the prediction 90% interval for the refractive change was 4.42 D, indicating a lack of predictability. The refractive error was not stable in some eyes; between 6 months and 4 years after surgery, 23% of eyes had a continued effect of the surgery of more than 1.00 D. For 323 patients with both eyes operated on, 64% stated they wore no optical correction. There were few serious complications. Eleven eyes (3%) lost two or three lines of best corrected visual acuity. Two eyes developed delayed bacterial keratitis without significant loss in best corrected visual acuity. (<i>JAMA</i>. 1990;263:1083-1091)
The Consultation
Authors: Vernon J. Louw
Journal: Annals of Internal Medicine (2012)

Ad Libitum1 May 2012The ConsultationVernon J. Louw, MBChB, MMed, PhDVernon J. Louw, MBChB, MMed, PhDFrom University of the Free State, Bloemfontein 9301, South Africa.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-156-9-201205010-00005 Audio Reading - “The Consultation” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "The Consultation," by V.J. Louw. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail i came closedyou saw the coverturned me upside downquickly ran the pagesthe essence of my beingflittingly fingeredby your practiced handsi found myselffacing judgmenton words you never readon stories you'd never knowbut you're sad to sayyou see clearly nowwho i amwhat i'm likeyou knowand you tell me your truthand send me awaywith pages torna book full of tearsunreadi leave exposedVernon J. Louw, MBChB, MMed, PhDUniversity of the Free StateBloemfontein 9301, South Africa Author, Article, and Disclosure InformationAffiliations: From University of the Free State, Bloemfontein 9301, South Africa.Current Author Address: Vernon J. Louw, MBChB, MMed, PhD, Division of Clinical Haematology, Department of Internal Medicine, University of the Free State, PO Box 339(G73), Bloemfontein 9301, South Africa. PreviousarticleNextarticle Advertisement Audio Reading - “The Consultation” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "The Consultation," by V.J. Louw. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 1 May 2012Volume 156, Issue 9Page: 634KeywordsHematology and oncology ePublished: 1 May 2012 Issue Published: 1 May 2012 Copyright & PermissionsCopyright © 2012 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Effect of warfarin on survival in small cell carcinoma of the lung. Veterans Administration Study No. 75
Authors: L. R. Zacharski
Journal: JAMA (1981)

In a controlled, randomized study, survival of patients with small cell carcinoma of the lung (SCCL) was prolonged on addition of warfarin sodium to combination chemotherapy plus radiation therapy. Median survival for 25 control patients was 24 weeks and for 25 warfarin-treated patients was 50 weeks. This difference could not be accounted for by differences between groups in performance status, extent of disease, age, or sex. The survival advantage associated with warfarin administration was observed both for patients with extensive disease and for those who failed to achieve complete or partial remission. The warfarin-treated group also demonstrated a significantly increased time to first evidence of disease progression. These results suggest that warfarin may be useful in the treatment of SCCL and also support the hypothesis that the blood coagulation mechanism may be involved in the growth and spread of cancer in man. (<i>JAMA</i>1981;245:831-835)
Human Physiology.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Human values in medicine: some helping organizations
Authors: M. O. Kepler
Journal: JAMA (1973)

Medical education is currently reflecting the general unrest and anxiety displayed by society in general, and it is critically examining its traditional curricular subjects and methods. There is some urging from students and a few educators for more emphasis on the humanistic aspects of medicine to help balance the customary stress on medical science. However, progress has been slow, and the means uncertain. In this somewhat discouraging atmosphere, there are some hopeful signs in the form of several national organizations actively seeking ways to implement programs in ethics and other human values in medical schools. These organizations and their objectives are described. The importance for human values in medical education is essentially to train physicians better equipped to care for the totality of man.
Abstract 1701: Deletion of β PDGF Receptor Dependent PI-3 Kinase and PLCγ Signaling Attenuates Vascular Smooth Muscle Cell Proliferation and Inhibits Neointima Formation in Mice
Authors: Evren Caglayan, Marius Vantler, Olli Leppanen, Lenard Mustafov, Felix Gerhardt, Margarete Odenthal, Kai Kappert, Stephan Rosenkranz
Journal: Circulation (2008)

Platelet-derived growth factor β-receptor (βPDGFR)-mediated proliferation of vascular smooth muscle cells (VSMC) plays a pivotal role in the development of restenosis. The βPDGFR binds and activates cytoplasmic signaling molecules such as Src, PI 3-kinase (PI3K), RasGAP, SHP-2 and phospholipase C-gamma (PLCγ). However, the βPDGFR-induced signaling pathways leading to cell cycle progression are largely unknown. In order to characterize the signaling molecules, which are important for βPDGFR-induced VSMC proliferation, we generated several stable VSMC lines with mutated βPDGFRs which were unable to bind/activate each individual signaling molecule. BrdU incorporation assays revealed PI3K and PLCγ as the main mediators of βPDGFR-mediated VSMC proliferation. Deletion of the binding sites for PI3K or PLCγ diminished DNA-synthesis about 47 ± 6% and 54 ± 5%, respectively, whereas the deletion of Src, RasGAP, or SHP-2 binding to the βPDGFR had no influence on the mitogenic response. Mutant cell lines which were only able to bind/activate PI3K or PLCγ induced 43 ± 4% and 52 ± 5% of the WT response, respectively. We further investigated the influence of PI3K and PLCγ on the distinct expression of the key players of cell cycle progression. Western blot analysis revealed that βPDGFR-activated PI3K mainly mediated the up-regulation of cyclin D1, whereas activation of PLCγ mediated the down-regulation of the cyclin-dependent kinase-inhibitor p27 kip1 . Consistently, βPDGFR-dependent phosphorylation of the retinoblastoma protein which is important for the G1/S transition was attenuated when either the binding of PI3K or PLCγ to the βPDGFR was abolished. Moreover, we confirmed our in vitro results in an in vivo model of balloon-induced carotid artery neointima formation. Mice lacking binding of PI3K and PLCγ to the βPDGFR (F3 mice) developed ~50% less neointima formation after balloon angioplasty compared to control WT mice after 3 weeks (p &lt; 0.05). These results indicate that the mitogenic signal of the β PDGFR is mediated by PI3K and PLCγ affecting distinct targets of cell cycle progression. Targeting specific downstream molecules of the βPDGFR in VSMCs might provide a novel approach to reduce neointima formation in patients undergoing balloon angioplasty.
Reply to Francesco Montorsi, Giorgio Gandaglia, Christoph Würnschimmel, Markus Graefen, Alberto Briganti, and Hartwig Huland's Letter to the Editor re: Paolo Afonso de Carvalho, Joāo A.B.A. Barbosa, Giuliano B. Guglielmetti, et al. Retrograde Release of the Neurovascular Bundle with Preservation of Dorsal Venous Complex During Robot-assisted Radical Prostatectomy: Optimizing Functional Outcomes. Eur Urol 2020;77:628–35. Incredible Results for Robot-assisted Nerve-sparing Radical Prostatectomy …
Authors: Vipul Patel
Journal: European Urology (2020)
Deaths related to coffee enemas
Authors: J. W. Eisele
Journal: JAMA (1980)

NATUROPATHIC therapies are increasing in popularity in the United States, and many of them rely primarily on alterations in diet. Although diet and nutrition are recognized as important adjuncts in cancer therapy,<sup>1</sup>conventional medicine rejects the concept of cancer therapy relying solely on dietary changes, and unlicensed practitioners of such therapy have been discouraged or prevented from practicing in the United States. Although these therapies may be of questionable therapeutic value, they are usually considered harmless. One regimen that relies primarily on a diet of natural foods combined with the ingestion of mixed potassium salts, Lugol's solution, thyroid extract, niacin, and pancreatin also includes coffee enemas administered as often as every two hours. This therapy has been recommended not only to patients with cancer but also to those with chronic, degenerative diseases. In the last two years we have noted two deaths in which the common factor was the
Domiciliary consultations.
Journal: BMJ (1988)

Domiciliary consultationsAs the domiciliary consultation service is specifically for patients who are unfit to attend hospital it is hardly surprising that Drs John Fry and Gerald Sandler found the highest rates of consultation in geriatric medicine (30 July, p 337).Some geriatric units have, however, abandoned domiciliary visits altogether, regarding them as a barrier to ad-
Incomplete Sentence in: Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and Adolescents
Authors: M Sirajul Islam, Stanley Midzi, Alejandro Cravioto, Hubert Endtz, Munirul Alam, Mohammad Ansaruzzaman, Pra- Dip Bardhan, Shah Faruque, Anwarul Iqbal, M Shafiqul Islam, Azharul Khan, Zahid Mahmud, Ramendra Mazumder, Firdausi Qadri, Kaisar Talukder
Journal: JAMA (2009)

disk diffusion) may fail to detect strains with reduced susceptibility.Longitudinal surveillance of antimicrobial susceptibility of V cholerae O1 using quantitative (MIC) methods is therefore recommended for early detection of emergence of resistance.
Development of a Virtual Benign Hematology Consultation Service: Results of a Pilot Project Involving 5 Medical Centers
Authors: Ashok Pai, Dinesh Kotak, Nancy Facher, Kyle Reader, Kevin Kong, Natalya Greyz, Jahan Tavakoli, Alfredo R. Lopez, Jerome G. Kim, Daniel Maloney, Raymond Liu, Tatjana Kolevska
Journal: Blood (2018)
PROTEIN KINASE CK1 ALPHA INACTIVATION CAUSES MANTLE CELL LYMPHOMA GROWTH ARREST AND SYNERGISTICALLY ENHANCES IBRUTINIB CYTOTOXICITY
Authors: S. Manni, M. Carrino, A. Fregnani, Quotti L. Tubi, A. Visentin, L. Trentin, G. Semenzato, F. Piazza
Journal: HemaSphere (2019)
American College of Cardiology/American Heart Association Expert Consensus Document on Electron-Beam Computed Tomography for the Diagnosis and Prognosis of Coronary Artery Disease
Authors: Robert A. O’Rourke, Bruce H. Brundage, Victor F. Froelicher, Philip Greenland, Scott M. Grundy, Rory Hachamovitch, Gerald M. Pohost, Leslee J. Shaw, William S. Weintraub, William L. Winters, James S. Forrester, Pamela S. Douglas, David P. Faxon, John D. Fisher, Gabriel Gregoratos, Judith S. Hochman, Adolph M. Hutter, Sanjiv Kaul, Robert A. O’Rourke, William S. Weintraub, William L. Winters, Michael J. Wolk
Journal: Circulation (2000)
Colon and rectal surgery
Authors: G. C. Oliver
Journal: JAMA (1989)

The rapid pace of technological advance requires monitoring and evaluation of the proposed application. Within colon and rectal surgery, at least seven new means to treat internal and external hemorrhoids or combinations thereof have been introduced recently. Indications for these newer treatments and an assessment of their utility were recently reviewed by Salvati.<sup>1</sup>The vast majority of hemorrhoidal problems can be managed in an ambulatory setting. Laser technology, including neodymium:yttrium-aluminum-garnet (Nd:YAG), argon, and carbon dioxide, has been been reported to be of use in the treatment of primarily internal hemorrhoidal disease. Early efforts to treat internal hemorrhoids using air transmission Nd:YAG via endoscopes or handheld probes have progressed to coagulation, coaptation, and excision by contact Nd:YAG scalpel.<sup>2</sup>Argon laser has been employed to treat internal hemorrhoids.<sup>3</sup>The wavelength of argon is selectively absorbed by certain pigments, of which hemoglobin is one. Theoretically, hypervascular tissues such as hemorrhoids
I-RAYS AND N-RAYS.
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cause of Diabetes . . . Helping Patients Stop Smoking
Journal: JAMA (1979)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Water Content and Proton Spin Relaxation Time for Malignant and Nonmalignant Tissues From Mice and Humans: Reply
Journal: JNCI Journal of the National Cancer Institute (1974)

Journal Article Water Content and Proton Spin Relaxation Time for Malignant and Nonmalignant Tissues From Mice and Humans: Reply Get access JNCI: Journal of the National Cancer Institute, Volume 52, Issue 2, February 1974, Page 626, https://doi.org/10.1093/jnci/52.6.626 Published: 01 February 1974