tbuckley/cabot-search huggingface dataset:
Highlights of the NCCN Oncology Research Program
Authors: Charalambos Andreadis, Erika Cavallone, Charlie Aoun
Journal: Journal of the National Comprehensive Cancer Network (2020)

This study is being conducted as a phase Ib, open-label, nonrandomized, single-institution study to evaluate the safety and tolerability of carfilzomib in combination with bendamustine and rituximab in patients with relapsed or refractory non-Hodgkin lymphoma (NHL; lymphoplasmacytic, marginal zone, follicular, mantle cell, diffuse large B cell) and to determine the recommended phase II dose and preliminary efficacy of this combination.The study will have 2 phases: a dose-escalation phase to determine the maximal tolerated dose (MTD) of carfilzomib in this combination in which participants will be monitored for toxicity, tolerability, and response, and a dose-expansion phase that will determine the preliminary efficacy in patients with mantle cell lymphoma or any other disease subtype in which there is a preliminary efficacy signal observed.Determination of the MTD will follow standard 313 design with escalation of the carfilzomib dose only.Dose levels of carfilzomib will be 15 mg/m 2 , 36 mg/m 2 , 56 mg/m 2 , and 70 mg/m 2 intravenously administered on days 2, 9, and 16.The last 3 cohorts will have a starting carfilzomib dose of 20 mg/m 2 on days 1 and 2. Bendamustine will be administered at the well-tolerated dose of 90 mg/m 2 intravenously on days 1 and 2. A dose de-escalation of bendamustine will occur if the starting dose proves intolerable in this combination.Rituximab will be given at a dose of 375 mg/m 2 on day 9 of cycle 1 and day 1 of subsequent cycles.
Compression of pulmonary artery by aortic aneurysm
Authors: R. M. Zeit
Journal: JAMA (1981)

ANEURYSMS of the ascending aorta may involve the main pulmonary artery or its branches by compression or by rupture and formation of an aortopulmonary artery fistula. While the diagnosis may be suggested from the chest roentgenogram, large midline ascending aortic aneurysms may be present yet not radiologically detectable. Diagnosis often requires pulmonary arteriography with visualization of the levophase as described herein. <h3>Report of a Case</h3> A 67-year-old woman had severe rightsided pleuritic chest pain, dyspnea, and hemoptysis for three days. The patient had been receiving warfarin sodium (Coumadin) for phlebitis but was unreliable in taking her medications. Her history included cancer of the bladder with bone metastasis and rheumatic heart disease. During physical examination, the patient was an anxious, diaphoretic woman in severe respiratory distress with considerable splinting of the right thorax. Her respirations were 24/min and blood pressure was 170/80 mm Hg. Breath sounds at the right base were
Floorward Thinking
Authors: Brandy E. Fisher
Journal: Environmental Health Perspectives (1999)

From its creation to its disposal, there are environmental and health problems associated with polyvinyl chloride (vinyl), the major component of vinyl flooring. The production of vinyl creates toxic waste that must be dumped or incinerated. Because very little vinyl is recycled, the waste material must also be landfilled or burned. Furthermore, the heavy chlorine content of these materials result in the release of dioxins into the environment. A new flooring alternative to vinyl recently entered the market. Stratica, manufactured by Amtico Company Limited based in Coventry, United Kingdom, is made from polymer resins and offers the durability of vinyl without the environmental impact.
PRESSORECEPTOR NERVES AND THYROTOXIC CRISES
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 2706: Neurocognitive Deficits Associated with Advanced Heart Failure
Authors: J. P Ginsberg, A. T Black, F. A Laws, J. Fridriksson, L. Bonilha
Journal: Circulation (2007)

The measures of general cognition which have previously been used to demonstrate cognitive impairment in patients with congestive heart failure (CHF) provide only broad indications of what cognitive function(s) in particular are impaired. The objectives of this study are: quantify the severity of neurocognitive impairment; use specific neurocognitive subtests to identify what functions are impaired; use fMRI to identify brain regions putatively involved in neurocognitive impairments of patients with advanced CHF. Hypoperfusion associated with CHF has been thought to be the primary cause of neuropathology in this population. We tested the hypothesis, suggested by our own preliminary data, that Verbal Fluency is impaired relative to Picture Naming and pathology of frontal lobe function is involved. Veterans with NYHA class III or IV CHF from our Advanced Heart Failure Clinic were given several cognitive tests, including the Addenbrooke Cognitive Exam (ACE). The ACE is a validated indicator of dementia comprised of four indices: Verbal Fluency, Language (Naming), Orientation, and Immediate Memory. Follow-up fMRI while performing Verbal Fluency and Picture Naming tasks was conducted to localize abnormalities of brain activation. Results showed that 64.5% of the group (n = 31, age = 62.3 (11.4) years) met the ACE cut-off score criterion of probable dementia (Total Score less than or equal to 88). Significantly lower scores on Verbal Fluency (p = .01), Language (p = .02), and Immediate Memory (p = .00), but not Orientation, were found in the probable dementia subgroup compared to the cognitively intact subgroup. After partialling out dementia status, ACE Total Score significantly correlated (r(31) = .31, p = .05) with cardiac output (measured with bioimpedance plethysmograhy). The fMRI procedure was administered on 7 patients. Activation patterns revealed absence of frontal activation (Brodmann Area 46) on Verbal Fluency relative to Picture Naming. In conclusion, many advanced heart failure patients appear to be undergoing a dementing process, and neurocognitive and neuroimaging results are consistent in suggesting impairment of explicit word generation and retrieval, but not semantic knowledge, with associated frontal lobe dysfunction.
MICHIGAN COLLEGE OF MEDICINE.
Authors: None B.
Journal: JAMA (1884)

New Hartford reports only one death for the month, a child of four months old that inherited consump¬ tion.An instance of death from freezing is reported from Saugatuck.A case where a child was killed by soothing syrup is stated to have occurred in Willing- ton.An unusual number of deaths from old age are reported from all parts of the State.Bridgeport re¬ ports six over 70, four of whom were over 80.One singular feature is the unusual prevalence of diarrhoeal diseases.Should this continue it would be an intimation to look out for cholera next summer.It is a bad time to clear up filth when an epidemic is present.The time, if prevention is to be accom¬ plished, is before the appearance of the disease.
The Relationship of Fluorosis and Brick Tea Drinking in Chinese Tibetans
Authors: Jin Cao, Xuexin Bai, Yan Zhao, Jianwei Liu, Dingyou Zhou, Shiliang Fang, Ma Jia, Jinsheng Wu
Journal: Environmental Health Perspectives (1996)

Brick tea-drinking fluorosis is an unusual environmental problem. As a result of an investigation of tea-drinking habits, total fluoride intakes, dental fluorosis, and skeletal fluorosis, this disease has been found in the Sichuan Province of China in Tibetans with a long history of drinking brick tea. The dental fluorosis investigation of 375 Tibetan children (213 males, 162 females) and 161 Han children (86 males, 75 females), 8-15 years of age, was carried out in Daofu County, Sichuan Province. According to the standard of the Chinese Health Ministry, a skeletal fluorosis survey of 658 Tibetans (264 males, 394 females) and 41 Hans (20 males, 11 females), all over 16 years old, was performed. The total fluoride intake and fluorosis were determined from a question--calculation method in all participants. The morbidities of dental fluorosis in Tibetan and Han children are 51.2% and 11.05%, respectively, and the indexes of dental fluorosis are 1.33 and 0.17 (chi 2 = 75.7, p < 0.01) respectively. The morbidity of skeletal fluorosis is 32.83% for Tibetan children and zero for the Han children. The fluoride intakes of Tibetan children and adults were 5.49 mg/person/day and 10.43 mg/person/day, respectively, in this area. Of total everyday fluoride intake, 94.2% by children and 94.4% by adults was from brick tea and zanba (r = 0.99).
OSTEOPATHY IN CONGRESS.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pituitary Adenomas
Authors: Mark J. Kupersmith
Journal: Annals of Internal Medicine (1995)

Letters15 March 1995Pituitary AdenomasMark J. Kupersmith, MD and David Kleinberg, MDMark J. Kupersmith, MDSearch for more papers by this author and David Kleinberg, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-122-6-199503150-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Siddiqui raises two important issues. First, if a patient as an apoplectic event with a pituitary adenoma, he or she might require emergent trans-sphenoidal surgery; such patients, even if they have prolactin-secreting tumors, may not be responsive to bromocriptine. However, none of our patients who had chiasmal compression during pregnancy had manifestations of hemorrhage on either magnetic resonance imaging or computed tomography scans. As is well known, microscopic examination of removed adenomas may show hemorrhage when neuroimaging has not. The second point concerns the question of why patients did not have surgical intervention during pregnancy. As shown ... Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 March 1995Volume 122, Issue 6Page: 476KeywordsAdenomasComputed axial tomographyHemorrhageMagnetic resonance imagingNeuroimagingPituitary tumorsPregnancySurgeryVision Issue Published: 15 March 1995 CopyrightCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Early PEG-interferon-related ALT flares of high magnitude lead to HBsAg decline and loss. A study of 639 chronic hepatitis B patients
Authors: Hannah S.J. Choi, Mina Farag, Willem Pieter Brouwer, Milan Sonneveld, Jordan Feld, Robert De Man, Bettina Hansen, Harry Janssen
Journal: Journal of Hepatology (2020)
MOTOR SUCTION OR VACUUM APPARATUS FOR REMOVAL OF BLOOD FROM THROAT IN TONSILLECTOMY
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Proceedings of the Thoracic Society
Journal: Thorax (1973)

in Quimper and spent much of his childhood in Nantes where his Uncle Guillaume was Head of the Faculty of Medicine.He was much influenced by his uncle and proceeded to Paris to study medicine, qualifying in 1802.His contact with Corvisart and Bayle stimulated his interest in res- piratory diseases and tuberculosis, from which he himself suffered.His clinical experience as well as his morbid anatomical studies at the Hopital Necker cul- minated in his invention of the stethoscope and his writing in 1819 de l'Auscultation mediate which may be regarded as the pioneer treatise from which modern chest medicine has developed.Despite his great success and renown in Paris, Laennec always retained a great love for his native Brittany and eventually, because of ill health, he was forced to retire there to his home at Kerlouarnec, near Quimper, where he died on 13 August 1826.A recent visit to France in search of various asso- ciations of Laennec is described.
Handbuch der normalen und pathologischen Physiologie, mit Berücksichtigung der experimentellen Pharmakologie.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE ACTION OF TUBERCULOUS TOXINS ON THE OFFSPRING OF THE TUBERCULOUS.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reestablishment of pulmonary-artery flow after prolonged complete occlusion. Studies in dogs
Authors: T. Gahagan
Journal: JAMA (1966)

The ability of the pulmonary vascular bed to accept normal blood flow after prolonged occlusion is important in corrective procedures for tetralogy of Fallot. Preparation of the pulmonary bed by systemic pulmonary shunt prior to complete correction has been considered advantageous by some. Although the final answer to this question will probably come from surgical statistics rather than laboratory experimentation, we thought it would be of interest to study pulmonary blood flow in dogs following reanastomosis of the pulmonary artery after periods of complete occlusion. <h3>Methods</h3> Direct measurement of left-lung blood flow in dogs weighing in the vicinity of 10 kg (22 lb) was obtained by individual cannulation of the three left pulmonary veins. Measurements were taken during a state of steady flow with mean systemic pressure maintained at 100 mm Hg and the blood volume kept constant by venous infusion of blood equal to that removed for measurement. Total
medical society approved plans, including blue shield, and private insurance programs
Journal: JAMA (1959)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Lymphoma biology
Authors: K Mihara, J Bhattacharyya, M Ohtsubo, Y Takihara, M Hoshi, A Kimura, T Loja, A Janikova, J Mayer, M Klabusay, P Mo ¨ller, S Bru ¨derlein, F Leitha ¨user, I Melzner, K Zimmermann, P Wiegand, M Buck, S Corbacioglu, M Malaise, A Viardot, H Shikata, Y Yakushijin, N Matsushita, A Sakai, A Sugita, N Nakamura, M Yasukawa, S Koivula, M Taskinen, R Louhimo, P Chen, J Delabie, H Holte, M Karjalainen-Lindsberg, M Bjo ¨rkholm, Ø Fluge, L Pedersen, M Jerkeman, M Eriksson, S Hautaniemi, S Leppa
Journal: Annals of Oncology (2011)
Antibody Deficiency Syndrome with Increased Gamma M (B2M) Globulins and Absent Gamma A (B2A) Globulins and Gamma2 (G) Globulins
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Das Wesen der Heilkunde.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal