tbuckley/cabot-search huggingface dataset:
Tax deduction of auto expenses
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Methods for Predicting Chronic Toxicity Parameters of Substances in the Area of Water Hygiene
Authors: S. S. Shigan
Journal: Environmental Health Perspectives (1976)

The development of rapid methods for determining chronic toxicity parameters of chemical compounds introduced by the oral route into an organism with water was studied. Formulas are verified with which threshold values and no-effect toxicity doses for substances can be obtained on the basis of various toxicologic parameters. For the example of organophosphates, a methodological scheme was developed for conducting an accelerated experiment for predicting the chronic toxicity of low and average cumulative compounds. Results are presented indicating the inadvisability of using lower animals as test subjects with the aim of predicting toxicity for higher animals. It is pointed out that patterns of homology and isomerism are observed in the comparison of chronic intoxication threshold doses as well as in acute toxicity values of substances.
Pianist's cramp to stage fright: the medical side of music-making
Authors: T. Ziporyn
Journal: JAMA (1984)

Music may soothe the savage breast, but it may not always soothe the musician. The same fingers producing those ethereal tones may be straining painfully as they reach across a string, and the same artistic temperament fiercely striking a chord may have been stricken with nearly incapacitating terror only moments earlier. A handful of physicians, many of whom play instruments themselves or have musical family members, are becoming aware of these unique medical problems. Although the ranks are still too small to call "music medicine" a full-fledged entity akin to sports medicine, communication between musicians and medical practitioners over the past few years is leading to consolidation of isolated experiences into a coherent body of knowledge. Early this summer, for example, Northwestern University in the Chicago suburb of Evanston, Ill, and the American String Teachers Association (ASTA) sponsored a conference on "The String Player's Stress Points—and Their Relief." Here, physicians
ANATOMY AND PHYSIOLOGY.
Journal: JAMA (1883)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Trial Protocol and Data Sharing Statement Missing From Supplements
Authors: Christine Jones
Journal: JAMA Internal Medicine (2019)

Krisda H. Chaiyachati, MD, MPH, MSHP; Judy A. Shea, PhD; David A. Asch, MD, MBA; Manqing Liu, MHS; Lisa M. Bellini, MD; C. Jessica Dine, MD, MSHP; Alice L. Sternberg, ScM; Yevgeniy Gitelman, MD; Alyssa M. Yeager, MD; Jeremy M. Asch, BA; Sanjay V. Desai, MD
Vasovagal Pseudohemorrhage
Authors: George L. Engel
Journal: JAMA (1977)

<h3>To the Editor.—</h3> It comes as a surprise to find as the title for an article such a curiosity as, "Vasovagal Pseudohemorrhage: Complication of Percutaneous Renal Biopsy" (23:1359-1360, 1977). Careful reading of the case protocol by Bolton et al suggests this to have been an instance of a prolonged vasopressor syncopal reaction, as occasionally occurs during minor injury or threat of injury, especially among subjects fearful of the experience. We have reported subjects who have remained syncopal, with bradycardia and postural blood pressure falling for more than two hours, in response to as trivial a threat as a venipuncture; recovery took place promptly on withdrawal of the threat.<sup>1</sup>Percutaneous renal and hepatic biopsy, indeed any invasive diagnostic procedure, provide almost paradigmatic conditions for the precipation of vasodepressor reactions in psychologically vulnerable subjects, reactions that may be prolonged in response to the alarmed (and alarming) behavior of the staff. These
Obstetrics and Gynecology
Authors: Edward C. Hill
Journal: JAMA (1986)

Of the various gynecologic concerns that will most directly influence interaction between the primary care physician and patient during the next few years, three have been selected for review as most timely and relevant. The incidence of invasive cancer of the cervix and the death rate from this malignancy have been steadily declining during the past 25 years. This trend is due, in large measure, to the early detection and treatment of cervical dysplasia and carcinoma in situ. These precursor lesions, being invisible to gross inspection, are discovered primarily by means of regular, routine Papanicolaou-Traut smears of the cervix. In the past, annual Papanicolaou smears have been routine, this interval having been chosen rather arbitrarily. Whenever such regular examinations are widely used, drastic reductions in cervical cancer mortality rates occur.<sup>1,2</sup> In 1980, the American Cancer Society,<sup>3</sup>on the basis of a report of a Canadian task force on
A MISAPPREHENSION.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Environmental Fate of Five Radiolabeled Coal Conversion By-Products Evaluated in a Laboratory Model Ecosystem
Authors: Po-Yung Lu, Robert L. Metcalf, Elaine M. Carlson
Journal: Environmental Health Perspectives (1978)

Anthracene, fluorene, carbazole, dibenzofuran, and dibenzothiophene are five typical by-products of coal conversion which are likely to be environmental pollutants.These were radiolabeled to high specific activity and purity by simple tritium exchange and evaluated for environmental fate in laboratory model ecosystems.Anthracene and fluorene were biologically converted to hydroxy and keto analogs.Carbazole was N-methylated and N-acetylated.Dibenzothiophene was microsomally oxidized to the sulfoxide and sulfone.Dibenzofuran was relatively inert to biodegradation.The octanol/water partition coefficient for the parent compounds was well correlated with ecological magnification indicating the possibility of predicting environmental behavior from physicochemical parameters.
Newborn screening: spotting for more
Authors: None The Lancet
Journal: The Lancet (2015)

Newborns are screened for rare, but serious, long-term disorders, before symptoms present, when an early diagnosis and appropriate treatment can be life-changing. As of Jan 5, 2015, the UK National Health Service's (NHS) Newborn Blood Spot Screening Programme will now screen for nine diseases by including an additional four rare genetic diseases: maple syrup urine disease (MSUD), isovaleric acidaemia (IVA), glutaric aciduria type 1 (GA1), and homocystinuria (pyridoxine unresponsive; HCU). If left untreated, these conditions can result in serious neurological outcomes and disability.
Human liver transplant perfusate: An abundant source of donor liver- associated leukocytes.
Authors: J Jonsson
Journal: Hepatology (1997)

In vitro studies designed to examine the mechanisms of immune tolerance after liver transplantation in humans have been hampered by the difficulty in obtaining sufficient numbers of donor liver-associated leukocytes (LALs). We have investigated whether the ex vivo perfusion of donor livers releases a population of LALs that can be readily retrieved from the waste fluid. The mean number of cells recovered after Ficoll-Hypaque density-gradient separation was 2.6 +/- 0.5 x 108 cells, with a viability of 94% +/- 2%. The perfusate lymphocytes comprised mainly T cells (39% +/- 2%) with a very low CD4/CD8 ratio and natural killer (NK) cells (56% +/- 6%) with an increase in the proportion of the CD3-CD56+CD16- subset. The activation marker CD69 was present on the majority of the perfusate lymphocytes. These are the phenotypic characteristics that have been previously reported for lymphocytes isolated from hepatic sinusoids. In mixed lymphocyte reactions, the perfusate cells showed a marked increase in the ability to stimulate allogeneic responder cells, resulting in 353% +/- 78% (P = .003) greater incorporation of [3H]thymidine in responder cells when compared with stimulation by donor peripheral blood mononuclear cells. The results show that large numbers of viable donor lymphocytes can be readily isolated from the liver perfusate solution. These cells have the characteristics of liver-associated lymphocytes with a predominance of activated NK and CD8+ T cells. This population can now be used in in vitro assays to elucidate the influence of donor leukocytes on the development of graft acceptance. (Hepatology 1997 Nov;26(5):1111-4)
<i>The Nervous System and its Diseases; a practical treatise on Neurology for the use of Physicians and Students.</i>By Charles K. Mills, M. D., Professor of Mental Diseases in the University of Pennsylvania; Clinical Professor of Neurology in the Woman's Medical College of Pennsylvania. Diseases of the brain and Spinal nerves, with a general introduction on the study and treatment of nervous diseases. With 459 illustrations. J. B. Lippincott Co., Philadelphia. 1898
Authors: G. J. P.
Journal: American Journal of Psychiatry (1898)
Prevalence of reflex anal dilatation
Authors: C J Hobbs, J. M Wynne
Journal: BMJ (1989)

The implications of these alterations in the most basic aspects of cardiovascular physiology are not clear, but they may need to be taken into account in the development ofnew treatments for the critically ill.Prospective studies have indicated that treat- ment based on some understanding of the pathophysiology of critical illness is associated with considerable improvements in survival.6Preventing gross errors in the management of acute critical illness is essential, but the ways to achieve this are not evident.Even with good treatment many patients go on to succumb to multiple organ failure, and research effort must now be directed to developing scientifically based treatments for this poorly understood condition.Unfortunately, research into shock, trauma, and critical illness does not fall cleanly within the remit of any of the principal charities or specialties with existing research infrastructures.Given the associated difficulty of research funding, I would hope that the national bodies like the Medical Research Council and the Department of Health have the foresight to encourage such research.With such scope for worthwhile advance it is regrettable that more funding is not forthcoming.
Investigation of the Biodurability of Wollastonite and Xonotlite
Authors: Bernd Bellmann, Hartwig Muhle
Journal: Environmental Health Perspectives (1994)

The in vivo durability of wollastonite materials, coated and uncoated, and of xonotlite was tested.Wollastonite is an anhydrous natural silicate and xonotlite is a hydrated synthetic calcium silicate.UICC crocidolite was used as a positive control with high durability.Using a dry-sizing technique, fractions from the stock materials were prepared according to the definition of "thoracic particulate mass" and "respirable particulate mass" of the American Conference of Governmental Industrial Hygienists.Fibers were instilled intratracheally into female Wistar rats, and the evenness of their distribution in the lung was checked by scanning electron microscopy (SEM).After serial sacrifices at 2 and 14 days, 1, 3, and 6 months, and low temperature ashing of the lung, the fibers were analyzed by SEM.The number and size distribution of fibers were investigated.The total number of crocidolite fibers decreased with a half-time of 240 days, but the number of fibers >5 pm in length was unchanged after 6 months.The elimination kinetics of wollastonite fibers from the lung were relatively fast, with half-times of 15 to 21 days.The coating of wollastonite in Wollastocoat had no effect on this elimination process.For the thoracic fraction of wollastonite, the elimination from the lung was as fast as for the respirable particulate fraction.The elimination kinetics of xonotlite from the lung was very fast.This material consisted of single crystals of acicular morphology with a median length of 1.3 pm and of agglomerates of these crystals.More than 99% of single crystals and about 85 to 89% of the agglomerates were already eliminated 2 days after instillation.
Michael Langman
Authors: A. Geddes
Journal: BMJ (2014)

Neural plasticity induced by stroke can mediate positive outcomes, such as recovery of function, but can also result in the formation of abnormal connections with negative consequences for perception and cognition. In three experiments using blood-oxygen level dependent (BOLD) functional magnetic resonance imaging, we examined the neural substrates of acquired auditory-tactile synesthesia, in which certain sounds can produce an intense somatosensory tingling sensation in a patient with a thalamic lesion. Compared with nine normal controls, the first experiment showed that the patient had a threefold greater BOLD response to sounds in the parietal operculum, the location of secondary somatosensory cortex. We hypothesized that this abnormal opercular activity might be the neural substrate of the patient9s synesthesia. Supporting this hypothesis, the second experiment demonstrated that sounds that produced no somatosensation did not evoke a BOLD response in the operculum, while sounds that produced strong somatosensations evoked large BOLD responses. These abnormal responses may have resulted from plasticity induced by the loss of somatosensory inputs. Consistent with this idea, in the third experiment, BOLD responses to somatosensory stimulation were significantly weaker in the patient9s operculum than in normal controls. These experiments demonstrate a double dissociation in the patient9s secondary somatosensory cortex (increased responses to auditory stimulation and decreased responses to somatosensory stimulation), and suggest both that stroke-induced plasticity can result in abnormal connections between sensory modalities that are normally separate, and that synesthesia can be caused by inappropriate connections between nearby cortical territories.
Medical Legislation
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pesticide-Related Illnesses Associated With the Use of a Plant Growth Regulator--Italy, 2001
Journal: JAMA (2001)

During January-February 2001, eight cases of acute illness in the county of Ragusa, Italy, were reported to the Italian National Institute for Health (INIH) by the Milan Poison Control Center (MPCC) and were attributed to exposure to Dormex, a plant growth regulator with hydrogen cyanamide as the active ingredient. These cases were identified during a pilot project for acute pesticide-related illness surveillance. Subsequent active case finding at health-care clinics by the Ragusa Occupational Health Unit identified six additional cases. MPCC identified nine cases in other areas of Italy. Of the 23 cases of acute illness, 22 resulted from occupational exposure during mixing and/or applying of Dormex, and one was from unintentional ingestion. This report summarizes the investigation of these cases, which implicates a pesticide as the causative agent and demonstrates the usefulness of surveillance for detecting pesticide-related illnesses.
An inactivated mycoplasma pneumoniae vaccine
Authors: K. E. Jensen
Journal: JAMA (1965)

An experimental vaccine was prepared with<i>Mycoplasma pneumonia</i>, the agent of primary atypical pneumonia. Its injection elicited antibody in rabbits and monkeys and induced resistance to multiplication of myoplasma in lungs of vaccinated hamsters. The vaccine was well tolerated in preliminary studies with 36 human subjects, and encouraging evidence of antigenicity was obtained when 25 of 30 developed significant rises in mycoplasma growth-inhibiting antibody titers. The response was best (17 of 19) in men in whom prevaccination antibody was absent or low. The vaccine was prepared with a new culture medium in which chloroform extract of egg yolk and a chemically defined salt-amino acid-vitamin solution was substituted for the allergenic horse serum and beef infusion components of standard medium.
Oral Ondansetron
Authors: Martin W. Oster
Journal: Annals of Internal Medicine (1991)

Letters1 August 1991Oral OndansetronMartin W. Oster, MDMartin W. Oster, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-115-3-233_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors:The new anti-emetic agent, ondansetron (Zofran; Glaxo Inc., Research Triangle Park, North Carolina) appears to be a major step forward in eliminating cancer chemotherapy-induced nausea and vomiting (1). However, a problem with ondansetron has been its recommended method of administration, which is 0.15 mg/kg body weight by intravenous infusion every 4 hours for three doses, starting 30 minutes before the chemotherapy is given. This method of administration is inconvenient for outpatients whose chemotherapy may only take 30 to 60 minutes to administer. For that reason, I wish to report that I have found a more convenient method...Reference1. CubedduHoffmanFuenmayorFinn LINA. Antagonism of serotinin S3 receptors with ondansetron prevents nausea and emesis induced by cyclophosphamide-containing chemotherapy regimens. J Clin Oncol. 1990;8:1721-7. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Columbia-Presbyterian Medical Center New York, NY 10032 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByRolling review: gastrointestinal malignancyOndansetron for patients given abdominal radiotherapy 1 August 1991Volume 115, Issue 3Page: 233-233KeywordsBody weightCancer chemotherapyChemotherapyNauseaOutpatientsVomiting Issue Published: 1 August 1991 PDF DownloadLoading ...
Questions and Answere
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal