tbuckley/cabot-search huggingface dataset:
Tuberculin Therapy
Authors: MILES J. BREUER
Journal: Annals of Internal Medicine (1931)

Article1 May 1931Tuberculin TherapyMILES J. BREUER, M.D., F.A.C.P.MILES J. BREUER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-4-11-1447 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe controversy over the efficacy of protein extracts of tubercle bacilli in the treatment of tuberculous patients, has seemed somewhat puzzling, and without solid ground to rest upon. Successful results are ardently claimed by some, and denied with equal emphasis by others. Usually this sort of a situation means that no rational basis has as yet been arrived at for the application of the treatment.It is only very recently that we have acquired accurate knowledge of the principles underlying the reaction of the animal body to tubercle bacilli and tuberculoprotein. However, at present we have a sufficiently comprehensive conception...References1 RICHMCCORDOCK : An Enquiry Concerning the Rôle of Allergy, Immunity, and Other Factors of Importance in the Pathogenesis of Human Tuberculosis, Bulletin of the Johns Hopkins Hospital, XLIV, No. 5, pp. 273, 424, May, 1929; page 307. Google Scholar2 WILLIS : Am. Rev. of Tuberc. 1928, XVII, p. 240. Google Scholar3 KRAUSE : Am. Rev. of Tuberc. 1917, 165. Google Scholar4 PETROFFSTEWARD : Jour. Immunol. 1926, XII, 97. Google Scholar5 BREUER : Ann. Int. Med., III, Jul. 1929, p. 57. LinkGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Lincoln, Nebraska PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1931Volume 4, Issue 11Page: 1447-1451KeywordsPatientsProteinsTuberculin Issue Published: 1 May 1931 PDF DownloadLoading ...
Stalkers
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: Hepatology (2017)

Emmanuel Tsochatzis, there is a mistake in the GFR formula, which should read as follows:GFR 5 45.9 3 (creatinine 20.836 ) 3 (urea 20.229 ) 3 (INR 20.113 ) 3 (age 20.129 ) 3 (sodium 0.972 ) 3 1.236 (if male) 3 0.92 (if moderate/severe ascites)We apologize for this mistake.
Obituary
Journal: BMJ (2004)

these qualities.However, we saw no differences in previous academic performance by group (table 2).A further argument against selection bias being a serious limitation in this study is the school's selection procedure.The three elements that contribute to this process are performance in a national admission test of reasoning and problem solving in the basic sciences and humanities, performance in a previous undergraduate degree, and performance at a standardised interview that rewards evidence of self directedness, teamwork, communication skills, compassion, resourcefulness, and broad life skills.Thus, all medical students at Flinders are likely to be resourceful and talented high achievers.Other qualities that could be over-represented in students in the rural programme and Darwin groups, such as seeking adventure, interest in rural medicine as a career, being suited to rural life, and having fewer ties with the city, show only the student centred benefits of offering different environments to suit the needs of different students.There is no suggestion that such qualities inherently affect academic performance, but when a student's self perceived traits are matched to an environment that supports them, their academic performance may be enhanced.This should, however, have been equally true for students who chose to study in the tertiary centre.Our analysis accounted for the other possible biases of student age, sex, year 2 score, and cohort effect.The results cannot be explained by the Hawthorne effect as they have been sustained over five years and during this time the rural and Darwin programmes have become a routine part of the school's study options.The results may also be criticised for reflecting the effect of group size rather than location.However, on a day to day basis, students in all of the locations were allocated to practices or wards in pairs or alone, and tutorial group sizes were also similar.
Highlights
Journal: JAMA (2017)

Reevaluation of Physician-Diagnosed Asthma in Adults 269In a prospective cohort study of 613 adults with a history of physician-diagnosed asthma in the past 5 years, Aaron and colleagues assessed whether a diagnosis of current asthma could be ruled out and asthma medications stopped.Participants were assessed with peak fl ow and symptom monitoring, spirometry, and bronchial challenge tests, and daily asthma medications were gradually tapered.The authors report that current asthma was ruled out in 203 study participants (33.1%) who were not using daily asthma medications or had medications weaned.In an Editorial, Hollingsworth and O'Connor discuss diagnosis and remission of adult-onset asthma.
Assuring the quality of health care for older persons. An expert panel's priorities
Authors: A. Fink
Journal: JAMA (1987)

To select topics for quality assurance activities focusing on older patients, we convened a 14-member panel of physicians and experts in quality assurance. In two rounds of ratings, panelists rated 42 medical conditions (eg, pneumonia) in terms of their effects on patient outcomes, the availability of beneficial interventions, and the health benefits from improving current quality. They rated 27 health services (eg, adult day-care) on similar dimensions. The feasibility of doing quality assurance work on each condition and service also was rated. Using the ratings, the conditions selected for quality assurance work were congestive heart failure, hypertension, pneumonia, breast cancer, adverse effects of drugs, incontinence, and depression. Health care services selected were hospital discharge planning, acute inpatient care for the frail elderly, long-term—care facilities (intermediate-care facilities and skilled nursing facilities), home health care services, and case management. (<i>JAMA</i>1987;258:1905-1908)
Health Services for Civilian Governmental Employees
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
An Atlas of Dermatology, Showing the Appearances, Clinical and microscopical, Normal and Abnormal, of Conditions of the Skin.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The role of surgery in resectable, nonresectable, and metastatic neuroblastoma
Authors: C. E. Koop
Journal: JAMA (1968)

The neuroblastoma is a unique tumor not only because of its apparent ability to change from a clinically and pathologically malignant tumor to one of a benign nature (ganglioneuroma) but also because of the remarkable gradient in histology exhibited by this tumor, the variable response according to the age of the patient, a prognosis definitely associated with the anatomical site of the tumor, and finally and perhaps most important to this discussion, what frequently appears to be a lack of correlation between the survival of the patient and the mode of surgical therapy.<sup>18-23</sup> Because the prognosis is so much more favorable in children under the age of 1 year, surgery without adjuvant therapy is considered by many to be sufficient treatment. (Only 28% of our survivors were over 1 year of age at the time of diagnosis.) The site of origin of the tumor has a definite effect upon
Trauma, PTSD, and Substance Use Disorders: Findings From the Australian National Survey of Mental Health and Well-Being
Authors: Katherine L Mills, Maree Teesson, Joanne Ross, Lorna Peters
Journal: American Journal of Psychiatry (2006)

Objective: The aim of the present study was to examine the association between trauma and posttraumatic stress disorder (PTSD) and substance use disorders and to examine the correlates of substance use disorder plus PTSD comorbidity in the Australian general population. Method: Data were collected from a stratified sample of 10,641 participants as part of the Australian National Survey of Mental Health and Well-Being. A modified version of the Composite International Diagnostic Interview was used to determine the presence of DSM-IV anxiety, affective, and substance use disorders and ICD-10 personality disorders. Results: Substance use disorder plus PTSD was experienced by a significant minority of the Australian general population (0.5%). Among those with PTSD, the most common substance use disorder was an alcohol use disorder (24.1%), whereas among those with a substance use disorder, PTSD was most common among individuals with an opioid use disorder (33.2%). Consistent with U.S. clinical literature, individuals with substance use disorder plus PTSD experience significantly poorer physical and mental health and greater disability than those with substance use disorder alone. In contrast, individuals with PTSD alone and those with substance use disorder plus PTSD shared a remarkably similar clinical profile. Conclusions: It is important that individuals entering treatment for substance use disorder or PTSD be assessed for this comorbidity. The addition of either disorder may present complications that need to be considered for the provision of appropriate treatment. Further research is necessary to ascertain which treatments are most effective in treating comorbid substance use disorder plus PTSD.
To Oxford
Authors: Martha Harwit
Journal: Annals of Internal Medicine (1992)

Ad Libitum15 September 1992To OxfordMartha Harwit, MDMartha Harwit, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-117-6-531 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptYellow roses on stately stone wallsvenerable ivy in venerable creviceswalking by the Thames gives a vista of the townnearly the same nowso I am toldas known by generations of scholars beforehow peaceful are the duckshow close is God herein the grasstiny farmhousessunset glowing over a fieldNo wonder I became so soon fondHow far is God herefrom an eight by ten room in the hospitalwith a phone and a pageron one side a laboratory crammed to the rafterson the other a roomwhere I have... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Stanford, CA 94305 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 September 1992Volume 117, Issue 6Page: 531-531KeywordsResearch laboratoriesWalking ePublished: 1 December 2008 Issue Published: 15 September 1992 PDF downloadLoading ...
Less maligned, but cut from the same cloth, other silicone implants also have adverse effects
Authors: T. Randall
Journal: JAMA (1992)

THE CURRENT controversy over silicone runs deeper than the problem of breast implants that rupture or bleed through their silicone shells (<i>JAMA</i>. 1992;267:2439-2442). At the heart of the controversy is the body's reaction to the polymer that for three decades has been championed as inert, noncytotoxic, and biocompatible. As a class of materials, silicone polymers are considered nontoxic in both animal and tissue culture studies. Millions of patients worldwide have received silicone implants, yet many researchers say that the long-term biocompatibility of silicone has never been thoroughly established scientifically. Only recently has the Food and Drug Administration begun to require the manufacturers of silicone breast, penile, and testicular implants to submit data from rigorous trials (<i>JAMA</i>. 1992;267:2578-2579). However these scientific questions are resolved, the result is likely to influence the fate not only of breast implants, but also the entire gamut of implants and devices that contain silicone. Since the
Combination therapy in head and neck cancer
Authors: B. S. Aron
Journal: JAMA (1975)

CANCER in the head and neck area is relatively easy to diagnose and usually remains localized; few patients die from distant metastases. However, it remains an important cause of morbidity and mortality in the United States. The American Cancer Society estimates that there will be 32,400 new cases in 1975 and that 11,450 patients will die from this disease. Surgery and radiation therapy have proved effective methods of therapy; chemotherapy may be useful in the future. These three modalities have their greatest effectiveness on different portions of the tumor: surgery in removing the central core, radiationin destroying the peripheral margin, and chemotherapy in ablating microscopic metastases. Small early epithelial cancers (T<sub>1</sub>, N<sub>0</sub>[tumor-node classification according to the American Joint Committee for Cancer Staging and End Results Reporting, 1968]) in the head and neck region are adequately treated by either surgery or radiation therapy, with high local
THE EXCELLENT WORK OF THE AMERICAN ACADEMY OF MEDICINE.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hepatology highlights
Authors: Jean‐François Dufour
Journal: Hepatology (2015)

HCV Therapy Three Orders of Magnitude Cheaper?Currently, a 12-week course of sofosbuvir/simeprevir costs $150,000.Van de Ven et al. calculated the minimum costs for a hepatitis C virus (HCV) treatment.They calculated the manufacturing costs for the large-scale generic production of sofosbuvir, ledipasvir, daclatasvir, elbasvir, grazoprevir, and ribavirin to treat 5 million patients yearly.The researchers arrived at prices going from $118 for a 12-week course of grazoprevir/ elbasvir to $298 for a 24-week course of sofosbuvir/ribavirin, with other combinations falling in between these values.Of course, this approach has important limitations, such as, for example, it ignores the important and necessary investments made in research and development.Nevertheless, as with the anti-human immunodeficiency virus (HIV) drugs, whose prices decreased over the years, the anti-HCV drugs can only become cheaper.(
Update: Outbreak of Legionnaires' Disease Associated With a Cruise Ship, 1994
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hepatic Amoebiasis
Authors: Th. Doxiades
Journal: BMJ (1964)

charged between the second and the sixth day from the Jessop Hospital for Women 158 were satisfied, even enthusiastic, with the arrangements, 28 were doubtful (nearly always because of inadequate help in the home), and only 13 said they were not satisfied.One felt unable to give an opinion, having been readmitted with secondary post- partum haemorrhage.In practice, many patients specially ask to be booked for 48 hotirs, and there are a few who should be confined in hospital for medical reasons who are clearly very unwilling to come in unless short stay is promised.Unlike Sir Andrew Claye I believe that for a proportion of patients the deliberate planning for a 48-hour discharge from maternity unit is the correct thing to do, for it provides the patient with the best of both worlds; this arrangement, however, must be -planned in advance and must be supported by efficient lines of communication and a real sense of team-work among those providing maternity care.Above all, the patient's home conditions must be suitable for early discharge, and in particular there must be sufficient help to give the mother enough pro- tection from the everyday affairs that she is going to have to take up again soon enough.-
Seat belt injury and regional enteritis
Authors: M. G. Robinson
Journal: JAMA (1971)

<h3>To the Editor.—</h3> Taylor's communication (<b>215</b>:1154, 1971) raises some disturbing questions about semantics in the already obscure definition of regional enteritis. Although the patient described may well have developed ischemic disease of the terminal ileum following blunt trauma of the abdomen, it seems unfortunate to use the term "regional enteritis" in this connection. Dr. Taylor might have been better advised to follow the lead of Fagin et al who recently described a case of ischemic enteritis mimicking regional enteritis.<sup>1</sup> Crohn has already published a warning regarding the attribution of regional enteritis to preceding trauma, although he too cites instances in which true traumatic ileitis seems to have occurred.<sup>2</sup>Certainly the etiological connection suggested by Taylor could have considerable impact in future civil litigation by patients who claim compensation for regional enteritis developing after possible innocuous trauma. Furthermore, the comment that negative prior history and "normal results of
Status Change to Open Access After Publication
Authors: Douglas Johnson, Fei Ye, Anna Dewan
Journal: JAMA Oncology (2019)

Takayuki Yoshino, MD, PhD; Takeharu Yamanaka, PhD; Eiji Oki, MD, PhD; Masahito Kotaka, MD, PhD; Dai Manaka, MD, PhD; Tetsuya Eto, MD; Junichi Hasegawa, MD, PhD; Akinori Takagane, MD, PhD; Masato Nakamura, MD, PhD; Takeshi Kato, MD, PhD; Yoshinori Munemoto, MD, PhD; Shintaro Takeuchi, MD, PhD; Hiroyuki Bando, MD, PhD; Hiroki Taniguchi, MD, PhD; Makio Gamoh, MD, PhD; Manabu Shiozawa, MD, PhD; Tsunekazu Mizushima, MD, PhD; Shigetoyo Saji, MD, PhD; Yoshihiko Maehara, MD, PhD; Atsushi Ohtsu, MD, PhD; Masaki Mori, MD, PhD