tbuckley/cabot-search huggingface dataset:
Prenatal and Postpartum Depression in Fathers and Mothers—Reply
Authors: James F. Paulson
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Wrong Percentage
Journal: JAMA (1982)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ritual and Belief in Morocco. Volume 1.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diffuse histiocytic lymphoma. The need for aggressive restaging
Authors: B. H. Weinerman
Journal: JAMA (1977)

Fifteen patients with stage III and IV diffuse histiocytic lymphoma were treated with combination chemotherapy: cyclophosphamide, vincristine sulfate, prednisone, and procarbazine hydrochloride (COPP). Eight achieved a complete clinical remission. Of these, five relapsed, but remission was reinduced in three of these. Median survival of partial responders was 52 weeks compared to more than 129 weeks for complete responders. Complete clinical remission in diffuse histiocytic lymphomas did not presage a long disease-free interval as has been reported in biopsy proved remission series. Biopsy and staging by pathologic examination appear necessary to document remission in this disease. (<i>JAMA</i>237:2403-2404, 1977)
The effect of gaps in health insurance on continuity of a regular source of care among preschool-aged children in the United States
Authors: M. D. Kogan
Journal: JAMA (1995)

<h3>Objective.</h3> —To estimate the prevalence and length of gaps in health insurance coverage and their effect on having a regular source of care in a national sample of preschool-aged children. <h3>Design.</h3> —Follow-up survey of a nationally representative sample of 3-year-old children in the US population by phone or personal interview. <h3>Participants.</h3> —A total of 8129 children whose mothers were interviewed for the 1991 Longitudinal Follow-up to the National Maternal and Infant Health Survey. <h3>Main Outcome Measures.</h3> —Report of any gap in health insurance for the children, the length of the gap, and the number of different sites where the children were taken for medical care as a measure of continuity of a regular source of care. <h3>Results.</h3> —About one quarter of US children were without health insurance for at least 1 month during their first 3 years of life. Over half of these children had a health insurance gap of more than 6 months. Less than half of US children had only one site of care during their first 3 years. Children with health insurance gaps of longer than 6 months were at increased risk of having more than one care site (odds ratio = 1.52; 95% confidence interval, 1.19 to 1.96). This risk further increased when an emergency treatment was discounted as a multiple site of care. <h3>Conclusions.</h3> —Having a gap in health insurance coverage is an important determinant for not having a regular source of care for preschool-aged children. This finding is of concern, given the sizable percentage of children in the United States who lacked continuous health care coverage during a critical period of development. (<i>JAMA</i>. 1995;274:1429-1435)
The Effect of Insulin and Potassium in Myasthenia Gravis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AMA diagnostic and treatment guidelines concerning child abuse and neglect. Council on Scientific Affairs
Journal: JAMA (1985)

Child maltreatment is a serious and pervasive problem. Every year, more than a million children in the United States are abused, and between 2,000 and 5,000 die as a result of their injuries. Physicians are in a unique position to detect child abuse and neglect and are mandated by law to report such cases. These guidelines were developed to assist primary care physicians in the identification and management of the various forms of child maltreatment. A brief historical introduction and specific information about vulnerable families and children are presented. The physical and behavioral diagnostic signs of physical abuse, physical neglect, sexual abuse, and emotional maltreatment are delineated. Information about specific techniques for interviewing the abused child and family, case management objectives, reporting requirements, and trends in treatment and prevention are also provided.
MENTAL ABERRATIONS.
Authors: L. T. HALL
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Selected Articles from This Issue
Journal: Clinical Cancer Research (2021)

Current treatments for diffuse lower-grade gliomas are noncurative, and patients with long-term disease control often experience disease- or treatment-related symptoms. Vorasidenib, a first-in-class, brain-penetrant dual inhibitor of mutant IDH1/2 (mIDH1/2), reduced tumor growth and levels of the oncometabolite D-2-hydroxyglutarate in an orthotopic mIDH glioma mouse model. In a phase I, first-in-human study, Mellinghoff and colleagues reported a favorable safety profile and preliminary clinical activity for vorasidenib at doses &lt;100 mg once daily in recurrent or progressive mIDH1/2 glioma. Introducing mIDH-targeted therap. during what is now the “watch-and-wait” period could potentially delay the need for more toxic treatments.Biomarkers are needed to identify patients with metastatic melanoma who will benefit from targeted therapy. Brase and colleagues analyzed biomarkers in pretreatment melanoma samples from the dabrafenib plus trametinib arm of the randomized, phase III COMBI-v trial using a large-scale digital pathology approach. High T-cell/low B-cell signatures were associated with improved overall survival compared to high T-cell/high B-cell signatures. Patients with high B-cell signatures had high tumor B-cell infiltration, decreased MAPK activity, and evidence of immunosuppression. These results suggest that B cells may serve as a prognostic marker for patients with melanoma to determine the utility of dabrafenib plus trametinib, although further validation of this work is needed.The standard of care for patients with locoregionally advanced, resectable cutaneous squamous cell carcinoma of the head and neck (CSCC-HN), is surgery followed by radiotherapy. However, this regimen is problematic for cosmetic and functional reasons, and due to recurrence. Ferrarotto and colleagues conducted a clinical trial of neoadjuvant PD-1 inhibition in patients with stage III-IVA CSCC-HN. This treatment strategy was, generally, well tolerated. Of 20 patients enrolled, the RECIST response rate was (30%), while the pathologic response rate (pCR and MPR) was 70%. Patients with pCR and MCR showed enhanced inflammation of the tumor microenvironment. These results are encouraging for the treatment of this disease, but further clinical trials are warranted.Androgen receptor (AR) inhibitors are a core treatment modality in metastatic prostate cancer, but cross-resistance between agents hinders sequential use. To explore genomic contributors to cross-resistance, Annala and colleagues analyzed 458 plasma cell-free DNA samples from 202 clinical trial patients receiving sequential AR inhibitors. Targeted and exome sequencing revealed frequent shifts in the somatic populations present in circulating tumor DNA after treatment. Acquired genomic alterations converged upon the AR gene. Recurrent acquisition of aggressive AR genotypes after multiple lines of AR inhibition treatment suggests that the AR remains a driver of resistance and a key therapeutic target.
"PYOSALPINX."
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hormonal regulation of human corticotropin-releasing hormone gene expression: implications for the stress response and immune/inflammatory reaction
Authors: N. C. Vamvakopoulos
Journal: Endocrine Reviews (1994)

Journal Article Hormonal Regulation of Human Corticotropin-Releasing Hormone Gene Expression: Implications for the Stress Response and Immune/Inflammatory Reaction Get access Nicholas C. Vamvakopoulos, Nicholas C. Vamvakopoulos 1Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health Bethesda MD 20892; and Department of Biology, University of Thessaly Medical School 412 22 Larissa, Greece *Address requests for reprints to: Nicholas C. Vamvakopoulos, Ph.D., National Institutes of Health, Building 10, Room 10N260, Bethesda, Maryland 20892. Search for other works by this author on: Oxford Academic Google Scholar George P. Chrousos George P. Chrousos 1Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health Bethesda MD 20892; and Department of Biology, University of Thessaly Medical School 412 22 Larissa, Greece Search for other works by this author on: Oxford Academic Google Scholar Endocrine Reviews, Volume 15, Issue 4, 1 August 1994, Pages 409–420, https://doi.org/10.1210/edrv-15-4-409 Published: 01 August 1994
Massachusetts Medical Society
Authors: John Figgis Jewett
Journal: New England Journal of Medicine (1965)

COMMITTEE ON MATERNAL WELFAREFatal Pancreatitis at Thirty-six WeeksA previously normal nineteen-year-old primigravida had an uneventful prenatal course until thirty-six weeks, when sudden abdominal pain and vomiting developed after dinner one evening. The symptoms then disappeared, recurring at 1 a.m. and continuing intermittently until examination at 11 a.m. disclosed moderate tenderness in the abdomen and left lumbar region, occasional mild uterine contractions and no cervical dilatation. The gestation seemed normal for thirty-six weeks, with a fetal heart rate of 140 and the vertex floating. The vital signs were normal.After admission for possible premature labor irregular contractions continued during . . .
Racial differences in survival from breast cancer. Results of the National Cancer Institute Black/White Cancer Survival Study
Authors: J W Eley, H A Hill, V W Chen, D F Austin, M N Wesley, H B Muss, R S Greenberg, R J Coates, P Correa, C K Redmond
Journal: JAMA (1994)

To examine the ability of recognized prognostic factors for breast cancer to account for the observed poorer survival in blacks compared with their white counterparts.
The 'Cured' Addict
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Negative immune regulator LNK/SH2B3 contributes to the development of autoimmune liver disease in mice under fatty-metabolic stress
Authors: Tatsuya Kanto, Taizo Mori, Sachiyo Yoshio, Hironari Kawai, Yuriko Tsutsui, Yuichi Yoshida, Shiori Yoshikawa, Yosuke Osawa
Journal: Journal of Hepatology (2020)
Duodenal Ulcer
Authors: Walter L. Palmer
Journal: JAMA (1961)

<h3>To the Editor:—</h3> InThe Journal, Aug. 6, 1960, page 1620, your consultant, in answering a question as to the amount of antacid required for the neutralization of the gastric contents in a patient with duodenal ulcer, has estimated a cost of $48.00 a month as the amount required to maintain a gastric pH at 4 for 16 hours a day. This is a fantastic amount. Calcium carbonate, as sold on prescription at our pharmacy, costs 75¢ a pound. The patient would have to use 2 lb. a day in order to spend $48.00 a month. We ordinarily prescribe 2 gm. hourly for 15 doses, or 30 gm. a day. At this rate 2 lb. should last the patient one month—$1.50 rather than $48.00. We prescribe calcium carbonate in bulk, permitting the patient to measure his own dose with a teaspoon.
Erratum for the Research Article: “A rapid triage test for active pulmonary tuberculosis in adult patients with persistent cough” by R. Ahmad, L. Xie, M. Pyle, M. F. Suarez, T. Broger, D. Steinberg, S. M. Ame, M. G. Lucero, M. J. Szucs, M. MacMullan, F. S. Berven, A. Dutta, D. M. Sanvictores, V. L. Tallo, R. Bencher, D. P. Eisinger, U. Dhingra, S. Deb, S. M. Ali, S. Mehta, W. W. Fawzi, I. D. Riley, S. Sazawal, Z. Premji, R. Black, C. J . L. Murray, B. Rodriguez, S. A. Carr, D. R. Walt, M. A. …
Journal: Science Translational Medicine (2019)
General practice audit of asthma in childhood.
Authors: M Levy, L Bell
Journal: BMJ (1984)

It has been suggested that asthma is underdiagnosed in children. We studied the records of 52 children with asthma in our group practice. Although asthma had been positively diagnosed in roughly 10% of the children aged 18 months to 11 years, to make the diagnosis required an average of 16 to 20 consultations for respiratory problems. According to the symptoms recorded before the diagnosis was made, only three quarters of the children had presented with wheeze and roughly a third had had difficulty in sleeping. We think that the doctor9s time would be better spent teaching patients about their asthma than by repeatedly treating non-existent respiratory infection.
Application of Homeostatic Principles to the Management of Nephritic Patients
Authors: Nathan B. Talbot, John D. Crawford, Gerald A. Kerrigan, Donald Hillman, Mary Bertucio, Mary Terry
Journal: New England Journal of Medicine (1956)

THE neuroendocrine-renal homeostatic mechanisms keep the water and electrolyte content of the body within physiologic limits by adjusting the urinary output of water and solutes in accordance with homeostatic needs. The functional capacity of these mechanisms normally is so large that healthy persons can vary their intake of foodstuffs and fluids over a wide range without suffering grossly perceptible metabolic disturbances. By contrast, the homeostatic capacity of patients with marked impairment of renal function may become so reduced that the intake of food and fluids must be kept within certain relatively narrow limits if water and solute intoxication and depletion . . .
A treatise on madness, by William Battie, MD, and remarks on Dr. Battie's treatise on madness, by John Monro; a psychiatric controversy of the eighteenth century.
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Secrets of inflammation only partly revealed
Authors: J. Kangilaski
Journal: JAMA (1981)

The best way to deal with inflammation and resulting pain may be to control the migration of circulating monocytic leukocytes. The key, according to Derek A. Willoughby, DSc, FRCPath, is to<i>control</i>rather than stop such migration because modern research has by no means disproved the old maxim that "inflammation is a salutary process." Since inflammation is a side effect of the efforts of leukocytes to deal with antigenic injury or insult, blocking WBC activity could well be harmful in the long run. Willoughby, who is professor of experimental pathology and director of rheumatological research at St Bartholomew's Hospital, London, was one of the speakers at a symposium on "Cellular Aspects of Inflammation" that was held in conjunction with the American Rheumatism Association meeting in Boston. Other speakers at the symposium were K. Frank Austen, MD, Theodore B. Bayles Professor of Medicine at Harvard Medical School, Boston; Christian René de