tbuckley/cabot-search huggingface dataset:
"THE CAUSE OF ABSCESS OF THE LUNG AFTER TONSILLECTOMY"
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
HFE Genotype in Patients with Hemochromatosis and Other Liver Diseases
Authors: Bruce R. Bacon, Robert S. Britton, John K. Olynyk
Journal: Annals of Internal Medicine (2000)

Letters1 February 2000HFE Genotype in Patients with Hemochromatosis and Other Liver DiseasesBruce R. Bacon, MD, Robert S. Britton, PhD, and John K. Olynyk, MDBruce R. Bacon, MDSaint Louis University School of Medicine; St. Louis, MO 63110-0250 (Bacon)Saint Louis University School of Medicine; St. Louis, MO 63110-0250 (Britton)Freemantle Hospital; Freemantle 6160 WA, Australia (Olynyk)Search for more papers by this author, Robert S. Britton, PhDSaint Louis University School of Medicine; St. Louis, MO 63110-0250 (Bacon)Saint Louis University School of Medicine; St. Louis, MO 63110-0250 (Britton)Freemantle Hospital; Freemantle 6160 WA, Australia (Olynyk)Search for more papers by this author, and John K. Olynyk, MDSaint Louis University School of Medicine; St. Louis, MO 63110-0250 (Bacon)Saint Louis University School of Medicine; St. Louis, MO 63110-0250 (Britton)Freemantle Hospital; Freemantle 6160 WA, Australia (Olynyk)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-3-200002010-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We thank Dr. McLaren for his thoughtful comments about our paper, which clearly described the value of HFE genotyping in patients with liver disease and possible iron overload. We agree with Dr. McLaren that the accompanying editorial by Franks and Burke (1) did not address the issue that we had described—that is, how to differentiate patients with hemochromatosis from those with liver disease and secondary iron overload or those with liver disease and abnormal serum iron measures. We believe our data clearly show the utility of HFE genetic testing in all patients with liver disease who have abnormal ...Reference1. Franks AL, Burke W. Will the real hemochromatosis please stand up? [Editorial]. Ann Intern Med. 1999;130:1018-9. LinkGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Saint Louis University School of Medicine; St. Louis, MO 63110-0250 (Bacon)Saint Louis University School of Medicine; St. Louis, MO 63110-0250 (Britton)Freemantle Hospital; Freemantle 6160 WA, Australia (Olynyk) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoWill the Real Hemochromatosis Please Stand Up? Adele L. Franks and Wylie Burke HFE Genotype in Patients with Hemochromatosis and Other Liver Diseases Gordon D. McLaren HFE Genotype in Patients with Hemochromatosis and Other Liver Diseases Lawrie W. Powell Metrics 1 February 2000Volume 132, Issue 3Page: 246KeywordsAlgorithmsGenetic testingGenotypingHemochromatosisLiver diseasesMutationPatients Issue Published: 1 February 2000 CopyrightCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Religion and Health
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Masthead: (Adv. Healthcare Mater. 8/2018)
Journal: Advanced Healthcare Materials (2018)

Citizenship: Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have focused on sharing our content with those in need, enhancing community philanthropy, reducing our carbon impact, creating global guidelines and best practices for paper use, establishing a vendor code of ethics, and engaging our colleagues and other stakeholders in our efforts.
FALLOUT AND THE PHYSICIAN
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Patient survival and instrument performance with permanent cardiac pacing
Authors: L. B. McGuire
Journal: JAMA (1977)

Among 313 patients who received cardiac pacemakers between 1961 and 1973, there was a 65% survival rate after five years, a progressive decrease in premature pulse generator failures, and a low, stable incidence of electrode malfunction. Decreased survival among more recently paced patients was attributed to an evolution of the selection for pacing that favored older patients with associated diseases. Death due to unexpected pacing failure was extremely rare. Premature pulse generator failures decreased from 0.8 per 100 pacing months among early units to 0.06 per 100 months among units implanted during 1971 to 1973, when a prophylactic replacement policy was in effect. Electrode revisions were required at a frequency of 0.5 to 0.8 per 100 months in both epicardial and endocardial systems. Electrode failures may limit the predictive value of surveillance systems, since these rely on a change of pacing frequency or pulse width to indicate battery depletion.
American Medical Association.
Journal: JAMA (1889)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hurricane Katrina Response and Guidance for Health-Care Providers, Relief Workers, and Shelter Operators
Journal: JAMA (2005)

Hurricane Katrina struck the coastal areas of Alabama, Florida, Louisiana, and Mississippi on August 29, 2005, causing substantial numbers of deaths among both humans and animals, infrastructure damage, and flooding. Affected areas continue to experience shortages of essential services, including electricity, potable water, food, and fuel; damage to health-care and public health systems; and disrupted communications. CDC/ATSDR, local and state health departments, other federal agencies, and other partners are supporting public health and medical-care functions for persons in affected areas and those displaced as a result of the hurricane.
Clofarabine administered weekly to adult patients with advanced solid tumors in a phase I dose-finding study
Authors: C. C. Cunningham, J. Nemunaitis, N. Senzer, S. Vukelja, J. Weiss, A. Ferrier, V. Vukovic, S. Weitman, D. Richards
Journal: Journal of Clinical Oncology (2004)

3115 Background: Clofarabine, a next-generation nucleoside analogue that inhibits DNA synthesis, has demonstrated activity in acute leukemia in Phase I and II trials. The agent has also shown potent cytotoxic activity in a wide range of solid tumor cell lines and therapeutic activity in murine tumor models. Methods: A Phase I dose-finding study is ongoing to determine the maximum tolerated dose (MTD) of clofarabine in patients with advanced solid tumors. To avoid the dose limiting toxicity of myelosuppression observed with the daily × 5 administration used for hematologic malignancies, clofarabine is administered IV on days 1, 8, and 15 of a 28-day cycle. Cohorts of patients are treated with escalating doses beginning with clofarabine 4 mg/m2 until MTD is determined. Results: Thirty patients have been treated in 8 cohorts; 3 each at 4, 6, 10, 14, 18, and 27.5 mg/m2, and 6 each at 22 and 34 mg/m2. MTD has not been reached and enrollment is continuing. Preliminary data are available for 21 patients who have completed at least 1 cycle of treatment in the first 6 cohorts (up to 22 mg/m2), 12 males and 9 females with a median age of 65 years (range 48 to 78). Tumor types include colorectal (5); non-small cell lung (3); squamous cell larynx, transitional cell bladder, and prostate (2 each); and adenosquamous gallbladder, bronchioalveolar, hepatocellular/cholangiocarcinoma, leiomysarcoma, melanoma, pancreas, and squamous cell esophagus (1 each). Six patients completed ≥3 cycles of treatment with 4 patients completing 4 cycles. Data on 20 of the 21 patients show that 7 had stable disease (SD) as their best response; 1 prostate cancer patient had a drop in PSA level from 7975 ng/mL at baseline to 934 ng/mL at end of study. Major toxicities include myelosuppression, nausea, vomiting, and fatigue. Conclusions: Clofarabine has been administered weekly for 3 weeks (days 1, 8, and 15) every 28 days to adult patients with solid tumors; no dose limiting toxicity has been observed, and the MTD has not been reached. Enrollment is ongoing in the 42.5 mg/m2 cohort. Author Disclosure Employment or Leadership Consultant or Advisory Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration ILEX Oncology, Inc., ILEX Products, Inc. an affiliate of ILEX Oncology ILEX Oncology, Inc., ILEX Products, Inc. an affiliate of ILEX Oncology ILEX Oncology, Inc.
Ophthalmology
Authors: Don C. Bienfang, Lisa D. Kelly, Don H. Nicholson, Robert B. Nussenblatt
Journal: New England Journal of Medicine (1990)

THIS article reviews some currently important topics in ophthalmology, chosen either because they are of general interest or because they concern the ophthalmologic expressions of systemic diseases. We obviously cannot cover the entire field of ophthalmology, nor do we attempt to cover all the details of each complicated problem.The Cornea and ConjunctivaInclusion ConjunctivitisInclusion conjunctivitis is a common, sexually transmitted disease caused by Chlamydia trachomatis serotypes D through K. There is an adult and a neonatal form of infection; in infants the eye is inoculated directly by cervical fluids during passage through the birth canal. Eye-to-eye transmission and . . .
SANITATION AND ETHICS.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reflections
Authors: Stuart Elovitz
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Declaration Of Helsinki
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Monitoring Treatment and Survival in Chronic Myeloid Leukemia
Journal: Journal of Clinical Oncology (1999)

PURPOSE: To monitor treatment results and survival in chronic myeloid leukemia after allogeneic bone marrow transplantation (alloBMT) and the introduction of interferon alpha (IFNα). PATIENTS AND METHODS: Disease course was monitored in 840 patients younger than 56 years who were registered onto prospective studies between 1984 and 1991 and were assigned to conventional chemotherapy (CHT) or IFNα therapy. One hundred twenty of these patients received allogeneic bone marrow in the chronic phase from an HLA-identical sibling without T-cell depletion (standard alloBMT). RESULTS: Patient distribution by risk and by presenting features was the same in the transplantation and nontransplantation cohorts, but age was different (median, 32 v 42 years). Results were analyzed by age and by Sokal's relative risk. Among low-risk patients, 10-year survival rates with standard alloBMT versus IFNα therapy versus CHT were 57% v 49% (P = .76) v 25% (P = .001), respectively, and among patients at higher risk, rates were 54% v 17% (P = .01) v 12% (P = .001). Among patients ≤ 32 years old, the 10-year survival rates were 65% v 35% (P = .05) v 24% (P = .001), respectively, but for patients older than 32 years, 10-year survival rates were 46% for standard alloBMT versus 31% for IFNα therapy (P = .62) versus 16% for conventional CHT (P = .05). The data did not change when the calculations were based on the transplantations that were performed within 1 year of diagnosis. CONCLUSION: Any policy of standard alloBMT was associated with significantly longer survival compared with conventional CHT, irrespective of age and risk. When the comparison was made with IFNα therapy, a policy of standard alloBMT, including early transplantation, was found to increase survival only in those patients who were younger or at intermediate or high risk.
Congenital hypotrichosis due to short anagen
Authors: M.M. Barraud-Klenovsek, R.M. Trueb
Journal: British Journal of Dermatology (2000)

Two children with congenital hypotrichosis are described. Both presented with persistent short, fine hair since birth. Evidence is provided that the short hair observed in these patients is due to a short anagen phase of the hair cycle, with a normal rate of hair growth. Shortening of the anagen phase of the scalp hair cycle leads to a decrease in the maximal hair length and an increase in the number of hairs in telogen, resulting in an increase in hair shedding. Scanning electron microscopy showed a widely spaced cuticular pattern, a finding typically seen in hair of thin calibre. One patient had affected family members with an apparently autosomal dominant mode of inheritance. The disorder appears to resolve spontaneously during puberty and adulthood.
Calculation Adjustment in Article on Waste and Savings in Health Care
Authors: Eli Cahan, Amanda Chawla, Kevin Shea, Cassandra Thiel, Leora Horwitz
Journal: JAMA (2020)

In Reply Mr Cahan and colleagues comment on our Viewpoint 1 on the importance of supply optimization in improving the value of health care delivery.We agree with the authors that reducing variability in surgical utilization can be accomplished through consolidating device vendors and integrating purchasing decisions in a way that does not inappropriately drive practice patterns.We only add a caveat that too much consolidation, for example to a single vendor, can increase risk of supply shortages and reduce the opportunity for effective price negotiations.There are many ways to increase value in health care by focusing on resource use and supply waste.Translational research that identifies and tests best practices for supply optimization in a variety of medical settings would enable more facilities to take advantage of this potential avenue for improvement.
Phase II Trial of Ofatumumab (OFA) for Older Patients and Patients Who Refuse Fludarabine-Based Regimens with Previously Untreated Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)
Authors: Ian W. Flinn, William N. Harwin, Patrick Ward, Habib H. Doss, Steven W. Papish, John D. Hainsworth, Jesus G. Berdeja, John C. Byrd
Journal: Blood (2012)
Abstracts 1-300
Authors: W Shearer, ~c Mo, Jk~ C~-~,D~-~, I Hamon, Fir_ Tan, Txfi~ Hcatslon, B Agostino, K Thompson, J Natvig, V Morrison, New Hyde, M Tristani-Firouzi, Eip Kamanga-Sollo, S Sun, A Mathur, H Jyonouchi, Minneapolis Mn, Allergens Dr, J-W Yunginger
Journal: Journal of Allergy and Clinical Immunology (1995)
Abstracts for Society of Nuclear Medicine and Molecular Imaging, Greater New York and New England Chapters, 29th Annual Northeast Regional Scientific Meeting November 6–8, 2015 Newport, RI
Journal: Clinical Nuclear Medicine (2016)

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