tbuckley/cabot-search huggingface dataset:
Acecainide for ventricular arrhythmias
Authors: J. K. Vyden
Journal: JAMA (1982)

<h3>To the Editor.—</h3> The recent editorial "Simple Tests Are Often Best" (1981; 246:1709) was a welcome voice of reason. Many physicians believe that the diagnosis of myocardial infarction must be supported by $500 worth of enzyme studies or that an ovarian cyst cannot be scheduled for surgery without expensive imaging confirmation. The clinical diagnosis is not only not stressed, but lack of extensive technological documentation may be considered poor practice of medicine. Many physicians coming from major centers believe that the daily practice of their profession should follow research protocols backed by an inexhaustible purse. Court decisions help downgrade clinical judgment. However, high technology should not replace clinical judgment but supplement it. The respectability of clinical decisions must be reestablished by the profession if we are to control the runaway costs. This is particularly valid in the light of the news that federal and state contributions to health care will
Review of Radiation Pneumonitis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
OXYGEN THERAPY
Authors: WALTER M. BOOTHBY
Journal: JAMA (1928)

Haldane,<sup>1</sup>from his investigations on carbon monoxide poisoning and other forms of oxygen deficiency, early recognized the dangers of anoxemia, especially its serious effect on the central nervous system, and called attention to many associated clinical conditions in which the administration of oxygen would be beneficial and even life-saving. During the World War he developed a portable apparatus for the administration of oxygen which was efficient in the treatment of gas casualties and also was manipulated with reasonable comfort to the patient. Barcroft,<sup>2</sup>in conjunction with his associates Hunt and Dufton, constructed three oxygen chambers in the physiologic laboratory at Cambridge, and by means of these studied the effect of prolonged oxygen treatment. Their patients were not as a rule dangerously ill but were suffering from the milder and more chronic types of disease. They were particularly interested in studying the effect of additional oxygen on the physiologic
Editor's Note: Grape Seed Proanthocyanidins Inhibit the Growth of Human Non–small Cell Lung Cancer Xenografts by Targeting Insulin-Like Growth Factor Binding Protein-3, Tumor Cell Proliferation, and Angiogenic Factors
Authors: Suhail Akhtar, Syed M. Meeran, Nandan Katiyar, Santosh K. Katiyar
Journal: Clinical Cancer Research (2018)

The editors are publishing this note to alert readers to a concern about this article (1): the IHC data presented in Fig. 5A in the two panels labeled "0.5% GSPs" appear to represent overlapping parts of the same image, even though they are labeled to represent different cell lines (A549 or H1299). Original data are not available for review.
<i>Announcement</i>: American Heart Month — February 2016
Journal: MMWR Morbidity and Mortality Weekly Report (2016)

February is American Heart Month.The leading cause of death in the United States continues to be heart disease.Although the death rate for heart disease has been decreasing (1,2), too few U.S. adults get adequate physical activity, eat a healthy diet, avoid smoking, and control their blood pressure and cholesterol.More than one in three U.S. adults have at least one type of cardiovascular disease (CVD), which includes heart disease, stroke, and high blood pressure.Nearly one in three deaths are attributed to CVD each year (1).In the United States about 17% of health care dollars are spent on CVD each year, which amounts to more than $316 billion in medical expenses and lost productivity (1).CVD and its risk factors are not distributed evenly across the U.S. population.Certain groups, defined by age, sex, race, ethnicity, or geography, have higher levels than others (1).Disproportionately high rates of avoidable CVD deaths are found among black men and among adults aged 30-74 years living in the Southeast, highlighting the need for targeted efforts to alleviate disparities and improve health (3).Black men experience a heart disease death rate twice that for white women, who have the lowest rate (4).CDC aims to reduce these disparities through increased use of clinical protocols (5), partnerships with national, state, and local organizations
"Normal-Pressure" Hydrocephalus
Authors: Lawrence Jacobs
Journal: JAMA (1976)

Analysis of 25 patients who fulfilled clinical and radiographic criteria for the diagnosis of "normal-pressure" hydrocephalus (NPH) demonstrated (1) a significant relationship between presence of motor signs with good outcome and absence of motor signs with poor outcome following ventricular shunting, (2) symptoms and signs of parkinsonism in 40% of patients in whom the diagnosis of NPH was made, and (3) no reliable relationship between radiographic measurements or cisternogram appearance and outcome following shunting. The clinical picture is the most important factor inselection of NPH patients for surgery. (<i>JAMA</i>235:510-512, 1976)
Man-made death: a neglected mortality
Authors: R. Rhodes
Journal: JAMA (1988)

HERMAN Biggs, an American pioneer in public health, identified "the reduction in the death rate" as "the principal statistical expression and index of human and social progress."<sup>2</sup>In<i>Twentieth Century Book of the Dead</i>,<sup>1</sup>a seminal but neglected 1972 study, Scottish writer Gil Elliot distinguishes between biologic death—death from natural causes directly—and man-made death—death from war, political violence, and their attendant privations. Historians and statisticians seldom have examined man-made death beyond counting the number of combatants killed, Elliot notes, although "the scale of man-made death is the central moral as well as material fact of our time."<sup>1(p6)</sup>Elliot's "nation of the dead," 100 million corpses, challenges that evasion with a powerful metaphor. Statistics on homicide and other unofficial violence locate and enumerate "private" man-made deaths for sociological examination and for comparison among political entities— cities, regions, and nations—by quality of life. By contrast, "public" man-made death is
Table of Contents
Authors: Andrea Palermo, Dario Tuccinardi, Luca Onofrio, Mikiko Watanabe, Daria Maggi, Anna Maurizi, Valentina Greto, Raffaella Buzzetti, Nicola Napoli, Paolo Pozzilli, Silvia Manfrini, Paul Richards, Sarah Ourabah, Jacques Montagne, Anne-Françoise Burnol, Catherine Postic, Sandra Guilmeau, Derek Hagman, Ilona Larson, Jessica Kuzma, Gail Cromer, Karen Makar, Katya Rubinow, Karen Foster-Schubert, Brian Van Yserloo, Peter Billing, Robert Landerholm, Matthew Crouthamel, David Flum, David Cummings, Mario Kratz, Jessica Alvarez, Elizabeth Chong, Douglas Walker, Joshua Chandler, Ellen Michalski, Ruth Grossmann, Karan Uppal, Shuzhao Li, Jennifer Frediani, Rabindra Tirouvanziam, Vilinh Tran, Vin Tangpricha, Dean Jones, Thomas Ziegler, Melania Manco, Giuseppe Nolfe, Zoltan Pataky, Lucilla Monti, Francesca Porcellati, Rafael Gabriel, Asimina Mitrakou, Geltrude Mingrone, Jaqueline Lepsch, Ilana Eshriqui, Dayana Farias, Juliana Vaz, Amanda Figueiredo, Amanda Rodrigues, Amorim Adegboye, Alex Brito, Rana Mokhtar, Lindsay Allen, Michael Holick, Gilberto Kac, Tina Brinkley, Xiaoyan Leng, Barbara Nicklas, Stephen Kritchevsky, Jingzhong Ding, Dalane Kitzman, W Gregory Hundley, Morgana Mongraw-Chaffin, Andrea Lacroix, Dorothy Sears, Lorena Garcia, Lawrence Phillips, Elena Salmoirago-Blotcher, Oleg Zaslavsky, Cheryl Anderson, Glucocorticoids Modulate, Human Brown, Adipose Thermogenesis, In Vivo, Hannah Scotney, Michael Symonds, James Law, Helen Budge, Don Sharkey, Konstantinos Manolopoulos, Charles Pickens, Lorraine Sordillo, Chen Zhang, Jenifer Fenton, Natalia Ferreira Mendes, Gisele Castro, Dioze Guadagnini, Natalia Tobar, Susana Cognuck, Lucila Leico, Kagohara Elias, Patricia Boer, Patricia Oliveira Prada, Yan Wang, Jia-Wen Shou, Xiao-Yang Li, Zhen-Xiong Zhao, Jie Fu, Chi-Yu He, Ru Feng, Chao Ma, Bao-Ying Wen, Xin-Yi Yang, Yan-Xing Han, Lu-Lu Wang, Qian Tong, Xue-Fu You, Yuan Lin, Wei-Jia Kong, Shu-Yi Si, Jian-Dong Jiang, A Synthetic, Nitraria Alkaloid, Isonitramine Protects Pancreatic Β-Cell, Attenuates Postprandial
Journal: Metabolism (2017)
The care of the patient in the teaching hospital
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effect of menstrual cycle and method of contraception on recovery of Neisseria gonorrhoeae
Authors: W. M. McCormack
Journal: JAMA (1982)

We examined the records of 5,287 women who were named as sexual contacts of men who had gonococcal urethritis in the National Gonorrhea Therapy Monitoring Study.<i>Neisseria gonorrhoeae</i>was recovered from endocervical cultures from 3,247 (61.4%) of the women. Participants who were seen during the first five days of the menstrual cycle were slightly more likely to have a positive culture (64.9%) than women who were seen on days 6 through 10 (61.3%), days 11 through 15 (60.0%), days 16 through 20 (59.8%), days 21 through 25 (60.4%), or after day 25 (61.2%). Similar data were obtained for 1,489 untreated women who presented because a recent screening culture contained<i>N gonorrhoeae. Neisseria gonorrhoeae</i>was isolated from pretreatment cultures from 231 (79.7%) of 290 such women who were examined during the first five days of their menstrual cycle and from 884 (73.7%) of 1,199 women who were examined later in their cycle. Method of contraception had no statistically significant influence on the recovery of<i>N gonorrhoeae</i>. (<i>JAMA</i>1982;247:1292-1294)
Cognitive behaviour therapy for adolescents with chronic fatigue syndrome: randomised controlled trial
Journal: BMJ (2005)

common in patients with osteoporosis compared with people with normal bone mineral density or osteopenia, stratifying for bone mineral density within the group with osteoporosis did not provide additional information.The three patients with multiple myeloma, however, all had evidence of established osteoporosis, suggesting that measurement of M component may be informative in this group.Referral patterns vary between osteoporosis clinics, depending on guidelines and the availability of bone densitometry.In our clinic, 46% of referred patients fulfilled the World Health Organization definition of osteoporosis.This agrees closely with the 41% to 53% 9 10 reported by clinics in the United Kingdom and United States. 11The most important limitation of our study was that we could not calculate the false negative rate.To do this we would have had to rule out non-secretory myeloma and light chain disease by carrying out skeletal x rays and marrow biopsies in all patients with osteoporosis referred to our clinic.It is possible, however, to estimate the number of false negative tests by extrapolating from Mayo clinic data on the distribution of multiple myeloma subtypes at diagnosis.The number of patients with multiple myeloma in our study is a conservative estimate, because we did not assess urine Bence-Jones protein.Light chain disease, however, is less common and the expense would be greater.Thus, about 600 urine analyses would be needed to diagnose a single case of light chain multiple myeloma in patients with osteoporosis if 20% 12 of cases of secretory multiple myeloma are of the light chain variant.We know from other studies that normal bone mineral density does not rule out multiple myeloma, 13 14 but owing to the low prevalence of the disease in referred patients without osteoporosis, we cannot make a strong case for vigilance for M component in the absence of osteoporosis.
Pain
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Minimally Invasive Surgery
Authors: J. Felsher, B. Chand, J. Ponsky
Journal: Endoscopy (2003)

The minimally invasive approach has become the standard of surgical care for numerous disease processes. In addition, refinements and advances in minimally invasive surgery are evolving more rapidly than ever. The growing experience of the laparoscopic surgeon and continued technical improvements are pushing the frontier of minimally invasive surgery ever forward. This review highlights the current aspects of endoscopic and laparoscopic surgery in 2001-2002 in relation to esophageal, gastric, adrenal, and pancreatic disease.
Long-Term Follow-up Results of IFM9903 and IFM9904 Trials Comparing Non Myeloablative Allotransplantation with Autologous Transplantation in High-Risk De Novo Multiple Myeloma.
Authors: Philippe Moreau, Frederic Garban, Michel Attal, Mauricette Michallet, Gerald Marit, Cyrille Hulin, Lotfi Benboubker, Chantal Doyen, Mohamad Mohty, Ibrahim Yakoub-Agha, Serge Leyvraz, Philippe Casassus, Hervé Avet-Loiseau, Laurent Garderet, Claire Mathiot, Jean-Luc Harousseau
Journal: Blood (2008)
ALBERT VON KÖLLIKER (1817-1905) WÜRZBURGER HISTOLOGIST
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Bioethics Advisory Commission holds first meeting to define governing principles of ethical research
Authors: C. Marwick
Journal: JAMA (1996)

ENSURING BETTER protection for human subjects who participate in biomedical and behavioral research and determining the appropriate use of genetic testing were 2 charges to the National Bioethics Advisory Commission at its inaugural meeting. The 18-member group met early last month at the National Institutes of Health (NIH) in Bethesda, Md, a year after President Clinton ordered its creation. Officially, the commission terminates in October 1997. But, said its chair, Harold T. Shapiro, PhD, "We're behaving as if the commission will go on for 4 or 5 years. Certainly we are designing our work for a longer horizon than 1 year." Shapiro is president of Princeton University, Princeton, NJ. <h3>Recommendations Requested</h3> The development of recommendations to ensure the well-being, autonomy, and privacy of human subjects undergoing experimental treatment, as well as recommendations for the appropriate use of genetic information, was requested of the 17-member commission by John H. Gibbons,
QLIF-18. DIGITAL PHENOTYPING: A NOVEL METHOD FOR QUALITY OF LIFE ASSESSMENT IN PATIENTS WITH BRAIN TUMORS
Authors: David Cote, Ian Barnett, Joeky Senders, Hassan Dawood, Patrick Staples, Lakshmi Nayak, J P Onnela, Timothy Smith
Journal: Neuro-Oncology (2017)

Digital phenotyping (DP) is a novel approach for moment-by-moment quantification of the individual-level human social and behavioral phenotype in-situ using data from personal digital devices. Here, we report the first application of DP in a population of patients with brain tumors. Participants installed Beiwe, a smartphone application designed for DP, on their phones. The application collects GPS, Wi-Fi, accelerometer, Bluetooth, text and call logs, voice recordings, and screen activity data, as well as daily pain surveys. Patients were enrolled only if they had radiographically- or pathologically-diagnosed brain tumors. A Generalized Estimating Equation (GEE) model was used to test for associations between pain and mobility. A total of 191 person-days of data were collected from 8 patients; 38% were men and mean subject age was 54 (range 40-68). Pathology included four pituitary adenomas, two glioblastomas, one low-grade glioma, and one meningioma. Daily survey response rate was 48.2% over a median follow-up of 28.5 days. The average daily score for pain was 4.2. Increased mobility in the 24 hours prior to taking a survey was found to be significantly associated with minor pain (as compared to no pain). Pain was significantly associated with four measures of mobility derived from GPS data. When compared to reporting no pain, mild pain (1 out of 10) was associated with a 9-fold expected increase in the distance traveled (in meters) in the previous 24 hours. Patients showed a 14-fold increase in radius of gyration traveled, a 9-fold increase in maximum diameter traveled, and an 11.5-fold increase in maximum distance traveled from home when comparing mild pain to no pain (all p<0.001). Brain tumors significantly impact patient behavior, functional status, and quality of life. DP is a novel method for evaluating those changes, and highlights associations between subjective pain and patient mobility.
Alkaline Phosphatase Activity of Polymorphs in Mongolism
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal