tbuckley/cabot-search huggingface dataset:
Progress Toward Elimination of Measles From the Americas
Journal: JAMA (1998)

From the Centers for Disease Control and PreventionLeads From the Morbidity and Mortality Weekly Report Atlanta, Ga pected measles cases were reported from the countries.Of these, 27,635 (31%) have been confirmed, 33,120 (37%) have been discarded, and 27,730 (31%) are under investigation.Of the 27,635 confirmed cases in 1997, a total of 26,919 (97%) were confirmed by laboratory testing or linked epidemiologically to a laboratory-confirmed case, and 716 (3%) were confirmed clinically, without laboratory investigation.Brazil (26,348 confirmed cases) and Canada (570 confirmed cases) accounted for 97% of the total confirmed cases in the region.The United States (135 cases), Paraguay (198), Guadeloupe (116), Argentina (96), Chile (59), Venezuela ( 27), and Costa Rica (15) all reported Ͼ10 confirmed measles cases during 1997. BrazilOf the 26,348 confirmed cases reported from Brazil, 20,186 (77%) were reported from Sa ˜o Paulo, the only state that did not conduct a follow-up measles vaccination campaign in 1995.Most cases during this outbreak occurred in persons residing in the greater Sa ˜o Paulo metropolitan area.Of the 19,322 confirmed measles cases reported from Sa ˜o Paulo for which patient age was known, 9938 (51%) occurred in persons aged 20-29 years.The highest age-specific incidence rates were reported for infants aged Ͻ1 year (456 cases per 100,000 population), young adults aged 20-29 years (156), and children aged 1-4 years (45).Many cases occurred among young adults who were members of groups congregating in enclosed environments, including male migrant workers from rural areas, students, health-care workers, tourist industry workers, and military recruits.Twenty measles-related deaths were reported; 17 (85%) occurred among infants aged Ͻ1 year.Genomic sequencing of virus isolates from Brazil, performed by CDC's Respiratory and Enteric Viruses Branch, demonstrated that the virus circulating in Sa ˜o Paulo was similar to virus isolates recently obtained from Western Europe, suggesting that the virus responsible for the outbreak may have been im-
Procedure for obtaining THC for cancer patients
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment options in advanced castration-resistant, docetaxel-resistant prostate cancer (ACRDRPC). Final results of a network meta-analysis
Authors: C. Cherubini, E. Bianchi, E. Tamburini, F. Drudi, L. Stocchi, S.V.L. Nicoletti, F. Perini, A. Venturi, F. Montanari, D. Tassinari
Journal: Annals of Oncology (2016)
A cluster of young patients with Burkitt's lymphoma and nasopharyngeal carcinoma in central Texas
Authors: L. P. Boss
Journal: JAMA (1985)

During a five-month period in 1982, diagnoses were made of Burkitt's lymphoma in three children and nasopharyngeal carcinoma in three teenagers who were residents of a small geographic area of central Texas. The observed number of these two Epstein-Barr virus-related cancers was significantly greater than the number expected in young patients based on Surveillance, Epidemiology, and End Results incidence rates. No epidemiologic associations were found linking any of the patients. Environmental studies including serological assays to determine a specific viral etiology were unrevealing. A search for new agents and the preservation of materials for future studies should continue to be a high priority in the evaluation of cancer clusters. (<i>JAMA</i>1985;253:2843-2846)
Echocardiographic and histopathological characterization of young and old transgenic mice over-expressing the human β1-adrenergic receptor
Authors: J.D. Port, H.D. Weinberger, J.D. Bisognano, O.A. Knudson, T.J. Bohlmeyer, A. Pende, M.R. Bristow
Journal: Journal of the American College of Cardiology (1998)
Dendritic Spines: Cellular Specializations Imparting Both Stability and Flexibility to Synaptic Function
Authors: K Harris
Journal: Annual Review of Neuroscience (1994)

The brain's default mode network consists of discrete, bilateral and symmetrical cortical areas, in the medial and lateral parietal, medial prefrontal, and medial and lateral temporal cortices of the human, nonhuman primate, cat, and rodent brains. Its ...Read More
M-Components
Authors: Neil Abramson
Journal: JAMA (1973)

Of 59 hospitalized patients with a monoclonal (M)-component, 15 had myeloma and 3 had macroglobulinemia. M-component was associated with other disorders in 24 of the patients and with no underlying disease in 17 of the patients. Bone marrow aspirates from patients with myeloma and macroglobulinemia contained more than 10% plasma cells; one half of other patients had more than 10% plasma cells. Clumps of plasma cells were unique for myeloma and macroglobulinemia but were present in only half of the cases. Generally, M-component was greater than 2.5 gm/100 ml with relative hypogammaglobulinemia. In four patients with hepatitis, the M-component disappeared. Precise differentiation between categories of M-components was difficult on the basis of laboratory findings alone. Specific clinical criteria for diagnosis of multiple myeloma and Waldenström's macroglobulinemia permitted separation from other causes of M-components.
Management of focal nodular hyperplasia and hepatocellular adenoma in young women: A series of 41 patients with clinical, radiological, and pathological correlations
Authors: D CHERQUI
Journal: Hepatology (1995)

Preoperative distinction between focal nodular hyperplasia (FNH) that should be managed conservatively and hepatocellular adenoma (HA) that should be resected remains difficult. The result is controversial management of these patients. The aims of this study were to report the value of modern imaging procedures for noninvasive diagnosis of these lesions, to assess the value of intraoperative frozen section studies, and to propose a management strategy in those patients. Fortyone consecutive women with FNH (35 cases) or HA (6 cases) treated at our institution between 1985 and 1992 were studied. New imaging techniques, including enhanced magnetic resonance imaging (MRI) and color Doppler ultrasonography (US), were prospectively appraised in addition to usual techniques. Histological examination of surgical specimens was obtained in all cases. A sixfold increase in the number of patients with FNH was observed during this study, whereas the number of patients with HA did not change. FNHs were incidental US findings in 74% of the cases. The best imaging procedure in the diagnosis of FNH was enhanced MRI with a sensitivity of 70% and a specificity of 98%. Color Doppler US was a useful adjunct. Intraoperative frozen section studies were performed in 16 patients with 19 tumors with a sensitivity of 89% and a specificity of 100%. From this study, we have come to the following conclusions: (1) in women, FNH is now much more often detected than HA; (2) using enhanced MRI, a preoperative diagnosis of FNH is possible in 70% of the cases, avoiding unnecessary surgery; (3) when clinical, biochemical, or imaging data are not typical of FNH, histological diagnosis is mandatory and can be safely and consistently made on large surgical biopsy specimens; (4) during surgery, a decision to resect or not resect a lesion can be efficiently assisted by frozen-section studies. (Hepatology 1995; 22:1674-1681).
Abstract 2612: Roles of USF1 in breast tumorigenesis and disease progression
Authors: Jessica Lewis, Iqbal Mahmud, Guimei Tian, Daiqing Liao
Journal: Cancer Research (2019)

Abstract Breast cancer accounts for nearly one-quarter of all cancer diagnoses and is the principal cause of cancer-related mortality in women worldwide. Triple negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer commonly resistant to therapeutics that have been successful in increasing survival in patients with ER+, PR+ and HER2+ breast cancer subtypes. As such, identifying factors that contribute to poor patient outcomes and mediate the growth and survival of TNBC cells remain important areas of investigation. USF1 (upstream stimulatory factor 1), a gene linked to drive lipogenesis and cellular proliferation, is overexpressed in human malignancies, yet its contribution to cancer remains unclear. In analyzing large number of genomic datasets including The Cancer Genome Atlas (TCGA), we found that USF1 expression is significantly higher in TNBC patient samples. Also, USF1 gene expression positively correlates with key lipogenic enzymes. Significantly, we found that high expression of USF1 in breast cancer correlates with decreased patient survival. We therefore hypothesize that USF1 promotes breast tumorigenesis and progression by activating lipogenic gene expression. We conducted pilot in vitro studies to determine the influence of USF1 expression and cell proliferation. It was demonstrated that knockdown of USF1 decreased cellular proliferation in 2D cell culture of the TNBC cell line MDA-MB-231. We also assessed the effects on USF1 expression levels on in vivo tumor growth. We found that USF1 overexpression and knockdown enhanced and reduced tumor growth in vivo, respectively. Further studies are underway to determine the mechanisms by which USF1 promotes TNBC tumorigenesis and metastatic progression. Our studies will shed lights on roles of USF1 in breast cancer tumor biology. (Supported by McKnight Foundation, Bankhead-Coley Cancer Research Program and James and Esther King Biomedical Research Program, Florida Department of Health.) Citation Format: Jessica Lewis, Iqbal Mahmud, Guimei Tian, Daiqing Liao. Roles of USF1 in breast tumorigenesis and disease progression [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 2612.
Fundamental Virology
Authors: Robert F. Betts
Journal: JAMA (1987)

This book, published in June 1986, is exactly what the editors describe it to be: "... it consists of a set of chapters excerpted from<i>Virology</i>[an earlier text published in 1985]. Its goal is to provide a text for graduate and upper level undergraduate students, researchers, scientists and investigators." There are approximately one half of the pages in the original and 33 rather than 63 chapters, including 17 introductory chapters covering aspects such as structure, taxonomy, viral membranes, and viral genetics. The only topic from the original missing here is diagnostic virology. Many chapters are excellent; for example, the chapter focusing on defective genomes is as inclusive as any I have seen on that subject. Virtually all of the chapters from the original of clinical relevance and several chapters on uncommon virus types have not been included. The remaining sections covering specific viruses focus on structure and replication, with little
A digital (r)evolution: introducing The Lancet Digital Health
Authors: None The Lancet Digital Health
Journal: The Lancet Digital Health (2019)

The digital future is rooted in our analogue past. It is therefore no surprise that The Lancet archives provide inspiration for this new journal's first Editorial. A 1959 article describes the potential uses of a computer in health care and rather charmingly states, “If it be objected that the machine is doing no more than imitate the mental processes of the medical practitioner, it can be pointed out that the machine needs less training, and is subject to fewer aberrations, than the doctor.” Fast forward 60 years: although computers can be found in virtually every room of a hospital—and in every doctor's pocket—technological advances in health care have not yet aligned with human expectations.
The Challenge of Childhood. Studies in Personality and Behavior.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Conference on Cellular Control Mechanisms and Cancer
Journal: JNCI Journal of the National Cancer Institute (1963)

Journal Article Conference on Cellular Control Mechanisms and Cancer Get access JNCI: Journal of the National Cancer Institute, Volume 30, Issue 5, May 1963, Page 1092, https://doi.org/10.1093/jnci/30.5.1092-a Published: 01 May 1963
Front &amp; Back Matter
Authors: Elena Tomba, Per Bech, Carlotta Belaise, Alessia Gatti, Virginie-Anne Chouinard, Guy Chouinard, Piero Porcelli, Domenico Laera, Domenico Mastrangelo, Angelo Di Masi, Christian Fazekas, Anton Leitner, Antonio Tundo, Andrea Murru, Isabella Pacchiarotti, Alessandra M.A. Nivoli, Francesc Colom, Eduard Vieta, Giovanni Castellini, Lorenzo Lelli, Carolina Lo Sauro, Linda Vignozzi, Mario Maggi, Carlo Faravelli, Anton J.L.M. van Balkom, Paul M.G. Emmelkamp, Merijn Eikelenboom, Adriaan W. Hoogendoorn, Johannes H. Smit, Patricia van Oppen, Gerhard Andersson, Björn Paxling, Pie Roch-Norlund, Gunnar Östman, Anna Norgren, Jonas Almlöv, Lisa Georén, Elisabeth Breitholtz, Mats Dahlin, Pim Cuijpers, Per Carlbring, Farrell Silverberg, Umberto Albert, Andrea Aguglia, Filippo Bogetto, Luca Cieri, Marinella Daniele, Giuseppe Maina, Roberta Necci, Anita Parena, Loretta Salvati, Valdo Ricca, Elena Tomba, Emanuela Offidani, Stefan Priebe, Nyla Bhatti, Kirsten Barnicot, Stephen Bremner, Amy Gaglia, Christina Katsakou, Iris Molosankwe, Paul McCrone, Martin Zinkler, Sarah E. Kirby, Lucy Yardley, Andreas Joos, Barbara Saum, Armin Hartmann, Oliver Tüscher, Ludger Tebartz van Elst, Almut Zeeck, Mark Zimmerman, Satz Mengensatzproduktion, Druck Reinhardt Druck Basel, Druck Reinhardt Druck Basel
Journal: Psychotherapy and Psychosomatics (2012)
Medicine over there
Authors: A. Brass
Journal: JAMA (1970)

Can any good thing come out of Indochina except half a million Americans on their way home? Ironically, yes: advances in medical knowledge and, for those physicians who have spent time there, a world of experience they could never have gained at home. This paradox is brought out in two fine new books<sup>1,2</sup>by physicians who are Vietnam veterans. But though Dr. Bourne and Dr. Eccles Smith both write as medical specialists— Bourne as a psychiatrist with a team studying stress from the Walter Reed Army Institute of Research, Eccles Smith the surgeon in charge of a civilian hospital in a battered coastal province—the scope of their reporting goes beyond the clinical. Their stories will give scant comfort to those who believe that the "battle for the hearts and minds" of the Vietnamese is being won by the government of the South and its allies, and that without peace
Erratum
Journal: JNCI Journal of the National Cancer Institute (1968)

In “Oxygenation Status of a Transplantable Tumor During Fractionated Radiation Therapy” by L. M. van Putten and R. F. Kallman, volume 40, number 3, March 1968, table 2 on page 447 is incorrect and should be replaced by: Table 2Open in new tabDownload slideAnoxic cell fractions calculated from paired observations of tumor irradiation in living and dead miceTable 2Open in new tabDownload slideAnoxic cell fractions calculated from paired observations of tumor irradiation in living and dead mice
Bronchial neoplasms and hormonal secretions.
Journal: BMJ (1967)

would be detected at a very early stage and the appropriate treatment could be instituted.In general, the earlier the diagnosis the more effectual the treatment.7The approach seems at the moment to stand a better chance of improving recurrence and survival rates than is likely to be accomplished by any foreseeable changes in treatment.If used on a national scale, with the original methods, this scheme of early detection would require vast resources.The new simplification may overcome this difficulty and make a development of this nature more probable.
Improvement of nutritive quality of foods
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Comparison of Three Mechanical Ventilators
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE PROGNOSIS OF INFANTILE TUBERCULOSIS
Journal: JAMA (1929)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Some new twists to one of most common procedures in US general surgery
Authors: M. F. Goldsmith
Journal: JAMA (1989)

CHANGES IN performing one of the most common procedures in general surgery were presented at the annual meeting of the American College of Surgeons, in Atlanta, Ga, by two innovators in the area of inguinal hernia repair. The techniques they describe are aimed at decreasing the pain, length of recovery time, and 20% recurrence rate heretofore often associated with this operation. Ralph Ger, MD, chair, Department of Surgery, Winthrop University Hospital, Mineola, NY, professor of surgery at the State University of New York, Stony Brook, and professor of anatomy at Albert Einstein College of Medicine, Bronx, NY, has perfected a technique using a laparoscope and a new stapling device. In Ger's hands, the minimally invasive technique routinely used for ligation of fallopian tubes to effect sterility in women is used to close the hernial opening in the abdominal wall while preserving fertility in men. Another aspect of hernia surgery was
Predicting Biological Effect as a Function of the Chemical Structure and the Primary Physical and Chemical Properties of Organic Compounds
Authors: N. G. Andreyeshcheva
Journal: Environmental Health Perspectives (1976)

The dependence of biological parameters on chemical structure was studied for a series of compounds with similar chemical structures. Computational formulas were developed on the basis of correlation and regression analysis. These formulas make it possible to predict the biological effect thresholds for a great number of organic compounds on the basis of their primary physical and chemical properties.