Effect of Patient Self-testing and Self-management of Long-Term Anticoagulation on Major Clinical Outcomes
Authors: Hanna E. Bloomfield, Brent C. Taylor, Timothy J. Wilt
Journal: Annals of Internal Medicine (2011)

Letters6 September 2011Effect of Patient Self-testing and Self-management of Long-Term Anticoagulation on Major Clinical OutcomesHanna E. Bloomfield, MD, MPH, Brent C. Taylor, PhD, MPH, and Timothy J. Wilt, MD, MPHHanna E. Bloomfield, MD, MPHFrom Minneapolis Veterans Affairs Health Care System, Minneapolis, MN 55417.Search for more papers by this author, Brent C. Taylor, PhD, MPHFrom Minneapolis Veterans Affairs Health Care System, Minneapolis, MN 55417.Search for more papers by this author, and Timothy J. Wilt, MD, MPHFrom Minneapolis Veterans Affairs Health Care System, Minneapolis, MN 55417.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-155-5-201109060-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We thank Dr. Siebenhofer and colleagues for their interest in our article. The subgroup analysis for thromboembolism comparing patient self-testing with patient self-management indicated a significant interaction (Peto odds ratio [OR] for self-testing, 0.84 [95% CI, 0.6 to 1.1]; for self-management, 0.43 [CI, 0.3 to 0.6]; P = 0.004) (1). However, because this was one of many post hoc subgroup analyses, results should be interpreted cautiously.With regard to our “major thromboembolic events” outcome, it is true that we only included strokes for the VA trial (2), even though our definition also included deep venous thrombosis, pulmonary embolism, and ...References1. Bloomfield HE, Krause A, Greer N, Taylor BC, MacDonald R, Rutks I, et al. Meta-analysis: effect of patient self-testing and self-management of long-term anticoagulation on major clinical outcomes. Ann Intern Med. 2011;154:472-82. [PMID: 21464349] LinkGoogle Scholar2. Matchar DB, Jacobson A, Dolor R, Edson R, Uyeda L, Phibbs CS, et al; THINRS Executive Committee and Site Investigators. Effect of home testing of international normalized ratio on clinical events. N Engl J Med. 2010;363:1608-20. [PMID: 20961244] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Minneapolis Veterans Affairs Health Care System, Minneapolis, MN 55417.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-2099. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoMeta-analysis: Effect of Patient Self-testing and Self-management of Long-Term Anticoagulation on Major Clinical Outcomes Hanna E. Bloomfield , Ange Krause , Nancy Greer , Brent C. Taylor , Roderick MacDonald , Indulis Rutks , Preetham Reddy , and Timothy J. Wilt Effect of Patient Self-testing and Self-management of Long-Term Anticoagulation on Major Clinical Outcomes Andrea Siebenhofer , Klaus Jeitler , and Ivo Rakovac Metrics 6 September 2011Volume 155, Issue 5Page: 336-337KeywordsConflicts of interestDeep vein thrombosisDisclosureIschemic strokePulmonary embolismStrokeThromboembolismTransient ischemic attacks ePublished: 6 September 2011 Issue Published: 6 September 2011 CopyrightCopyright © 2011 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...