tbuckley/cabot-search huggingface dataset:
PCB and PCDF Congeners in the Blood and Tissues of Yusho and Yu-Cheng Patients
Authors: Yoshito Masuda, Hiroaki Kuroki, Koichi Haraguchi, Junya Nagayama
Journal: Environmental Health Perspectives (1985)

Polychlorinated biphenyl (PCB) poisonings occurred in western Japan, where it is called Yusho, in 1968, and in central Taiwan, where it is called Yu-Cheng, in 1979.The average concentrations of PCBs in the adipose tissue, liver and blood of Yusho patients and in the blood of Yu-Cheng patients were 1.9 ppm, 0.08 ppm, 6.7 ppb and 99 ppb, respectively.Seven PCB congeners, such as 2,4,5,3 ',4'-pentachloro-, 2,3,4,3',4'- pentachloro-, 2,4,5,2',4',5'-hexachloro-, 2,3,4,2',4',5'-hexachloro-, 2,3,4,5,3',4'-hexachloro-, 2,3,4,5,2',4',5'- heptachloro-and 2,3,4,5,2',3',4'-heptachloro biphenyls were identified in the blood and tissues of patients with Yusho and Yu-Cheng and controls.The concentration of 2,3,4,5,3',4'-hexachlorobiphenyl was com- paratively higher in the patients than in controls.The concentrations of polychlorinated dibenzofurans (PCDFs) in the adipose tissue and liver of Yusho patients were 6 to 13 ppb and 3 to 25 ppb, respec- tively, while no PCDFs were detected in the controls.Major PCDF congeners identified in the tissues and blood of Yusho and Yu-Cheng patients were the 2, 3,6,8-tetrachloro-, 2,3,7,8-tetrachloro-, 1,2,4,7,8- pentachloro-, 2,3,4,7,8-pentachloroand 1,2,3,4,7,8-hexachlorodibenzofurans (DFs), of which the 2,3,4,7,8- pentachloro compound was predominant.The concentrations of methylthio-PCB in the liver, lung and adipose tissue of Yusho patients were 0.1 to 0.5, 0.2 to 1.4 and 0.5 to 1.0 ppb, respectively, and those of methysulfone PCBs were 0.3 to 0.7, 1.0 to 2.5 and 0.7 to 1.0 ppb, respectively.Some of the major peaks of the PCB methylthio and methylsulfone derivatives were identical in gas chromatographic reten- tion times with those of 4-methylthioand 4-methylsulfone-2,5,2',5'-tetrachlorobiphenyl PCDFs, especially 2,3,4,7,8-pentachloro DF, appear to be mainly responsible in the poisonings.
Energy Transported Across Closed Chest Wall
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
European Perspectives
Journal: Circulation (2009)

Working with Ken Bloch, MD, he cloned the gene responsible for the production of nitric oxide in endothelial cells.Since then, he has taken it from the gene to transgenic animal models-small animals, then large-to clinical trials, and then to the coronary care unit."At the time, nitric oxide was one of the most fascinating molecules that was discussed, and we sensed that it was important for the heart and for the circulation, but the gene that was responsible for the production of nitric oxide in the heart was not known," he recalls."Over the past 10 to 15 years we've been working with lots of genes involved in nitric oxide biology and how it applies to cardiac disease." "The Start of My Real Interest in Learning About What It Is That Makes People Sick, ot Just Physiology and Symptoms, but Mechanisms of Disease"Professor Janssens' decision to pursue medicine at the University of Leuven, where he received his MD in 1984, is attributable to a high school role model who had chosen it for a career path.The scientific interest came during his first year as an intern when he was supervised by Marc Decramer, MD, PhD, now chief of the hospital's pulmonary division, but at the time a young staff member who had spent a couple of years doing research training in Montreal, Canada."He was the one who inspired me to learn the science," says Professor Janssens."All of the other people I had worked with were MDs mainly focusing on clinical medicine with limited scientific interest."At that time in Europe, medical students studied physiology, with a bit of pathology and biochemistry thrown in, but little emphasis was placed on the mechanisms of disease.Molecular biology was still a new subject, and it first became established in the research laboratories in the United States.Professor Janssens says, "He [Decramer] got exposed to basic science, and that was the start of my real interest in learning about what it is that makes people sick, not just physiology and symptoms, but mechanisms of disease.
A Manual of Bandaging; Adapted for Self-Instruction.
Authors: None E. W. A.
Journal: JAMA (1885)

This is a useless little volume since it contains much discarded rubbish of obsolete names and the terminology of a past generation. It is full of references to " charpie " the "plumasseau," "Gateau," "boulette," " bourdounet," "pelote," "cataplasma carbonis," and other strange and barbaric things which modern surgery has no use for. It is evident enough where the writer's mistake occurred. In compiling his " manual " he used one or two little works on bandaging which are still extant upon the shelves of older practitioners. The book has every appearance of having been made to order by one who knew little or nothing about the subject. A little more practical experience would have taught him that more than half his elaborate bandages with their queer long names would not work in practice, in fact have been discarded long ago, if they ever were in use. It may be that they are still popular
Substance abuse and anesthesiology training
Authors: J. S. Matsumura
Journal: JAMA (1990)

<h3>To the Editor.—</h3> Although addiction in anesthesiology has serious and potentially fatal consequences, the conclusions of Menk et al<sup>1</sup>regarding reentry of the addicted anesthesiology resident are incorrect. This study is an incomplete survey of program directors whose responses may have been altered by their historical perspective or level of understanding of addictive disease. It is plausible that the inherent bias of these studies was exaggerated, in that directors with catastrophic experiences (brain injury or death) would be more likely to respond to the questionnaire than those with "minor difficulties." Over a 14-year span, 31 programs did not report a single case of substance abuse, which suggests that the study by Menk et al is missing a number of residents with a less visible expression of their disease. The validity of the recommendation by Menk et al that parenteral opioid abusers be redirected into another specialty depends on the
Journal of Neurochemistry, London
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Autoimmunity as the Consequence of a Spontaneous Mutation in Rasgrp1
Authors: Katrin Layer, Guosheng Lin, Alessio Nencion, Wei Hu, Adam Schmucker, Andrey N. Antov, Xiaoyu Li, Satoshi Takamatsu, Timothy Chevassut, Nancy A. Dower, Stacey L. Stang, David Beier, Janet Buhlmann, Roderick T. Bronson, Keith B. Elkon, James C. Stone, Luk Van Parijs, Bing Lim
Journal: Immunity (2012)
Massachusetts Medical Society
Authors: John Figgis Jewett
Journal: New England Journal of Medicine (1959)

COMMITTEE ON MATERNAL WELFARECongestive Heart Failure, with Hypertrophy of the Right VentricleA thirty-seven-year-old gravida 5, para 4, died at thirty-two weeks with convulsions and congestive heart failure. This patient had been followed for ten years because of heart disease and syncope. Fainting was diagnosed by electroencephalography as a form of epilepsy, probably aggravated by circulatory insufficiency. Extensive studies, including cardiac catheterization, revealed pulmonary hypertension, but surgery for congenital dilatation of the pulmonary artery was deferred when the earlier diagnosis of defect of the interatrial septum was discarded. Eminent consultants advised the patient against additional pregnancies after the third, . . .
Ecological Aspects of Mercury-Selenium Interactions in the Marine Environment
Authors: Karlin Beijer, Arne Jernelov
Journal: Environmental Health Perspectives (1978)

In the marine environment, mercury is accompanied by selenium in all investigated species of mam- mals, birds, and fish-possibly due to a normal homeostatic regulation.It therefore seems likely that selenium will exert its protective action against mercury toxicity in the marine environment, decreasing its detrimental effects on reproduction, behavior, growth, etc. of the organisms and thus protect the popula- tion and ecosystem.On the other hand, the increased retention of mercury caused by selenium may lead to a higher level of biomagniflcation in the food chain and a higher body burden in the individual.This might counteract the positive effect of decreased intoxication.
More Midwife Education Needed for Home Water Births
Journal: JAMA (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pediatrics, Springfield, Ill.
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
An anticancer C-Kit kinase inhibitor is reengineered to make it more active and less cardiotoxic
Authors: Ariel Fernández, Angela Sanguino, Zhenghong Peng, Eylem Ozturk, Jianping Chen, Alejandro Crespo, Sarah Wulf, Aleksander Shavrin, Chaoping Qin, Jianpeng Ma, Jonathan Trent, Yvonne Lin, Hee-Dong Han, Lingegowda S. Mangala, James A. Bankson, Juri Gelovani, Allen Samarel, William Bornmann, Anil K. Sood, Gabriel Lopez-Berestein
Journal: Journal of Clinical Investigation (2013)
Spiritual needs and patient satisfaction in multi-cultural patient population.
Authors: Alan Bennett Astrow, Gary Kwok, Rashmi Kumar Sharma, Daniel Sulmasy
Journal: Journal of Clinical Oncology (2015)

e20589 Background: We previously reported an association between unmet spiritual needs and decreased satisfaction with care among hem/onc outpatients at a Manhattan cancer center. We now report on spiritual needs in a multi-cultural group of 727 hem/onc outpatients in Brooklyn, NY using a revised instrument validated in English, Chinese, Spanish, and Russian. Methods: We administered the Spiritual Needs Assessment for Patients (SNAP) to a convenience sample of hem/onc patients from the Maimonides Cancer Center, 2 private practices, and a public hospital clinic. The SNAP is a 23-item survey that comprises psychosocial, spiritual, and religious domains. Patients were also asked to complete a demographic survey, the QUEST satisfaction with care scale, and questions about physician inquiry into their religious and spiritual needs. Results: The majority (68%) were female, with 44% non-Hispanic white, 13% Hispanic, 25% African American, 14% Asian. English was the primary language for 57%, Spanish 9%, Chinese 11%, Russian 15%. Seven percent identified as Buddhist, 32% Catholic, 7% Eastern Orthodox, 2% Muslim, 20% Jewish, 23% Protestant; 59% considered themselves “spiritual but not religious.” At least one specific spiritual need was reported by 79%. Spiritual needs not being met reported by 23%; 11% wanted help with spiritual needs. Half (51% and 48%) would feel comfortable having their physician ask about their religious beliefs or spiritual needs. Russian-speaking (p < .001), Jewish (both English and Russian-speaking) (p < .001), and Eastern Orthodox patients (p = .001) had significantly lower spiritual needs scores compared with median. Patients with a higher spiritual needs score, those whose spiritual needs had not been met, and those that needed help with their spiritual needs reported significantly lower satisfaction with care (p = .046, p < .001, p = .008) and lower perception of quality of care (p = .008, p < .001, p < .001). Conclusions: Spiritual needs are common in an ethnically, religiously, and linguistically diverse urban cancer patient population, but may differ by religious and cultural background. High levels of spiritual need are associated with lower levels of satisfaction with and perception of quality of care.
Maternity in Newcastle Upon Tyne—A Community Study
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A QUESTION OF PRIORITY.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Feeding of Infants. Home Guide for Modifying Milk.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hepatitis and hepatitis-associated antigen in 56 mother-infant pairs
Authors: I. L. Schweitzer
Journal: JAMA (1972)

Hepatitis and the hepatitis-associated antigen (HAA) were studied in 56 mothers who had acute viral hepatitis during pregnancy or within six months of delivery and their infants who were tested for HAA at least once. Twenty-six mothers were HAA-positive during the acute illness, and HAA was found in the infants of ten. In 17 of these women HAA-positive hepatitis occurred within two months of delivery, and eight of their babies were found to be HAA-positive. Hepatitis-associated antigen was found in two of 19 cord bloods tested. The antigen appeared to cross the placental barrier in three cases, and neonatal contamination at birth seemed to occur in one. Persistent antigenemia and protracted subclinical hepatitis were found in all HAA-positive babies.
Peer Review
Authors: John T. Flynn
Journal: JAMA (1973)

<h3>To the Editor.—</h3> Dr. Peterson's experience (224:884, 1973) suggests that medical students are more willing to accept peer review than are their older colleagues in residency programs or in practice. The medical student is inexperienced, is not actually responsible for the life-and-death care of the patient, and is more easily influenced by the strongly expressed opinions of his teachers and professors. Before Dr. Peterson commits himself completely to the position that peer review should be taught to medical students, he should wait several years and check with these same individuals whom he has so instructed, to determine any changes of attitude that may have occurred after they graduated, after they had assumed positions of direct responsibility for patients, and after they had matured in their judgment of professional matters. Peer review, like motherhood, is good; but do not try to sell us the idea on the basis of the reactions
The Elegant Eighties When Chicago Was Young
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Clinical Trials
Authors: Robert S. Gordon
Journal: New England Journal of Medicine (1978)

With the advent of sophisticated biostatistical methods, clinical trials have acquired scientific respectability during the past two decades. Public concern about the costs and benefits of medical care, in addition to conventional scientific scepticism, is increasingly motivating thoughtful physicians to look for controlled-trial data to justify practices that in the past have been defended as generally accepted. Another force tending to stimulate the initiation of clinical trials is the growing role of the federal government as a consumer of, and payer for, medical care. Decisions about allowable benefits or practices, made in a Professional Standards Review Organization or in the . . .