Cancer of the large intestine.
Journal: BMJ (1969)

Response to Oral Glucose Load: Strong statistical association shown between fasting glyceride Cancer of the Large Intesti e levels and response of blood glucose and plasma insulin (pp.595 and 599).Carcinoma of the large bowel is the second commonest killing cancer in Liver and the Pill: In puerperal women pure the United Kingdom, being exceeded only by carcinoma of the bronchus.oestrogen reduced bromsulphalein excretion but The Registrar General's figures for 1966 showed that carcinoma of the pure progestogen did not (p.602).Leader at colon in England and Wales accounted for some nine thousand deaths p. 592.Predicting Rh Iso-immunization: Liquor bili.and of the rectum for another five and a half thousand.'A lethal disease rubin/protein ratio found inferior to bilirubin of this magnitude presents many problems, but perhaps the most imporlevel (p.605).tant are: How can diagnosis be made at the earliest possible stage ?Haemoglobinopathies: Article from Ghana How can treatment be made more effective ?And what can be offered advocates haemoglobin typing and genetic coun-to the patient who has advanced or recurrent disease ?selling policy to reduce manifestations of sickle- A symposium at the Association of Surgeons meeting in London this cell disease (p.607).Asmoima h solto o ugosmem odntl cell dieae 60year discussed precancerous lesions of the large intestine.B. C. Morson2Bruceliosis: London outbreak of Br. melitensis stressed that, though there is no scientific proof that neoplastic polyps infection traced to Italian cheese (p. 612).inectioralIchedtn No Itaianfichse (p.r612).become malignant, there is much evidence of a circumstantial nature to Cerebral Ischaemia: No significant improve- th ment found in double-blind trial between support the generally accepted view that they do.Thus the sequence of dipyramidole and placebo (p.614).neoplastic polyp to cancer can be recognized by simple macroscopic Maturity-onset Diabetes: Failure of adipose inspection, and polyps which appear benign sometimes show areas of tissue to metabolize glucose demonstrated (p.invasive carcinoma.Conversely, evidence of residual benign tumour may 616).be seen in growths which are obviously cancerous.Some 25 0 of surgical Chicken-pox: Complicated by non-traumatic specimens removed for carcinoma show associated benign adenomatous rupture of spleen (p. 617).polyps, and in such cases second primary cancers are found twice as often Anxiety States: When to refer, and how to pre-as in those patients who have no associated polyps.Solitary adenomas, vent (p. 619).papillary adenomas, and villous papillomas do not differ in their histology Metabolic Bone Disease: Management discussed from the polyps of familial polyposis, which are undoubtedly precancerous.in " Today's Drugs " (p.621 ).Medicine in New Towns: Plans for Milton A further interesting point is that both adenomas and carcinomas are Keynes (p.628).Progress and experience at produced by carcinogenic agents in the experimental animal.Livingston New Town (p.632).Many of these polyps lie within -reach of the sigmoidoscope, but K. C. Bilharziasis: Recommendations of First African Simpkins and A. C. Young' point out that the double-contrast barium Symposium (p.634).enema enables tiny polyps to be diagnosed beyond the reach of this instru-Personal View: Lord Platt (p.636).ment.Tumours which are more than 1 cm. in diameter and are irregular in outline are likely to be malignant and should be removed.If regular Letters: On outpatient anaesthetics, Abortion an une 1cm thy anb kptndrevwby aimeea Act, anticoagulants in cardiac infarction, cer-Vocational Training: Meeting between Council cancers develop in patients who are on average about 20 years younger deputation and G.M.C. (Supplement, p,. 88).than the generality of patients with cancer of the large bowel.Factors General Medical Council: Meeting of Discithat predispose to malignant change in colitis are: long duration of the plinary Committee (Supplemtenzt, p,. 95).disease, involvement of the whole large bowel, onset in youth, chronic