Body Mass Index and Risk for End-Stage Renal Disease
Authors: Micah L. Thorp
Journal: Annals of Internal Medicine (2006)

Letters2 May 2006Body Mass Index and Risk for End-Stage Renal DiseaseMicah L. Thorp, DO, MPHMicah L. Thorp, DO, MPHFrom Kaiser Permanente Northwest, Milwaukie, OR 97267.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-144-9-200605020-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Hsu and colleagues (1) found a significant correlation between body mass index (BMI) and subsequent renal replacement therapy. Perhaps because of the generous sample size, lengthy follow-up, or survival bias, the relationship was more substantial than previously reported. This finding provides an important insight in determining the significance of BMI in the development of renal disease, a relationship that is both complex and not yet fully understood.Although increased BMI may be associated with the development of renal disease (and subsequent renal replacement therapy), it is an association that may change throughout disease progression. Studies examining risk ...References1. Hsu CY, McCulloch CE, Iribarren C, Darbinian J, Go AS. Body mass index and risk for end-stage renal disease. Ann Intern Med. 2006;144:21-8. [PMID: 16389251] LinkGoogle Scholar2. Bonnet F, Deprele C, Sassolas A, Moulin P, Alamartine E, Berthezene F, et al. Excessive body weight as a new independent risk factor for clinical and pathological progression in primary IgA nephritis. Am J Kidney Dis. 2001;37:720-7. [PMID: 11273871] CrossrefMedlineGoogle Scholar3. Evans M, Fryzek JP, Elinder CG, Cohen SS, McLaughlin JK, Nyren O, et al. The natural history of chronic renal failure: results from an unselected, population-based, inception cohort in Sweden. Am J Kidney Dis. 2005;46:863-70. [PMID: 16253726] CrossrefMedlineGoogle Scholar4. Kalantar-Zadeh K, Kopple JD, Kilpatrick RD, McAllister CJ, Shinaberger CS, Gjertson DW, et al. Association of morbid obesity and weight change over time with cardiovascular survival in hemodialysis population. Am J Kidney Dis. 2005;46:489-500. [PMID: 16129211] CrossrefMedlineGoogle Scholar5. Kalantar-Zadeh K, Abbott KC, Salahudeen AK, Kilpatrick RD, Horwich TB. Survival advantages of obesity in dialysis patients. Am J Clin Nutr. 2005;81:543-54. [PMID: 15755821] CrossrefMedlineGoogle Scholar6. Chagnac A, Weinstein T, Korzets A, Ramadan E, Hirsch J, Gafter U. Glomerular hemodynamics in severe obesity. Am J Physiol Renal Physiol. 2000;278:F817-22. [PMID: 10807594] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Kaiser Permanente Northwest, Milwaukie, OR 97267.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBody Mass Index and Risk for End-Stage Renal Disease Chi-yuan Hsu , Charles E. McCulloch , Carlos Iribarren , Jeanne Darbinian , and Alan S. Go Body Mass Index and Risk for End-Stage Renal Disease Kamyar Kalantar-Zadeh and Joel D. Kopple Body Mass Index and Risk for End-Stage Renal Disease Chi-yuan Hsu , Carlos Iribarren , and Alan S. Go Metrics Cited ByUpdate in General Internal MedicineDarrell W. Harrington, MD and Mark T. Munekata, MD, MPH* 2 May 2006Volume 144, Issue 9Page: 700-701KeywordsBody mass indexEpidemiologyInflammationMalnutritionMedical risk factorsOverweightRenal diseasesRenal failureVitamin D ePublished: 2 May 2006 Issue Published: 2 May 2006 CopyrightCopyright © 2006 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...