tbuckley/cabot-search huggingface dataset:
Large cell bronchogenic carcinoma. Prolonged disease-free survival following chemotherapy
Authors: G. J. Vosika
Journal: JAMA (1979)

INCREASINGLY, reports of effective multidrug chemotherapy programs for small cell carcinoma of the lung are describing remission rates of 60% to 90%, prolonged survival,<sup>1</sup>and possible cure.<sup>2</sup>Results of such multidrug regimens for patients with lung carcinoma of types other than small cell have been less encouraging, with only modest overall response rates and increase in survival.<sup>3,4</sup>I treated a patient who was originally seen in March 1973 for metastatic large cell carcinoma of the lung with chemotherapy only. At this time, four years later, and after two years without specific antitumor therapy, he is free of detectable disease. A recent thoracotomy showed only scar tissue that was the result of healing atypical mycobacterial infection. <h3>Report of a Case</h3> A 47-year-old man noted a right inguinal mass 11 months prior to his first hospital admission. Several weeks previously, he noticed a right preauricular cutaneous lesion. Physical examination
False elevation in serum creatinine levels
Authors: D. Herrington
Journal: JAMA (1984)

<h3>To the Editor.—</h3> Flucytosine causes a falsely elevated serum creatinine measurement when an analytic method using creatinine iminohydrolase is employed.<sup>1</sup>This enzymatic assay is being introduced into many hospital laboratories, replacing systems with which flucytosine did not interfere. <h3>Report of a Case.—</h3> A 53-year-old man with alcoholic cirrhosis and cryptococcal meningitis was receiving therapy with amphotericin B (0.3 mg/kg/day) and flucytosine (150 mg/kg/day). His serum creatinine level, which was 1.0 mg/dL prior to drug therapy, rose to 3.2 mg/dL on the fourth day of therapy. The dosing regimen was altered because of the possibility of amphotericin-related renal dysfunction and the consequent possibility of bone marrow toxic reaction from flucytosine. Serum creatinine values then fluctuated on a daily basis, with a high of 6.3 mg/dL, a low of 1.1 mg/dL, and a mean of 3.5 mg/dL. It was discovered that creatininemeasurements were being determined on a Kodak Ektachem 400
Transplant problems
Authors: A. R. Holder
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Full-text medical literature retrieval by computer. A pilot test
Authors: M. F. Collen
Journal: JAMA (1985)

A pilot test of a full-text, medical literature retrieval service demonstrated its capabilities for on-line search and retrieval of references, abstracts, and/or full-text journal articles. During a three-month test period, more than 500 health care professionals conducted 9,377 searches using computer terminals located in seven different health care sites. Searches were initiated for purposes of patient care, medical education, research, or for browsing. The majority of responders to a questionnaire given during the test period said they would continue to use the service during the pilot test, and only about 1% reported the search process difficult to use or not "user-friendly." It is predictable that with a comprehensive data base, full-text medical literature retrieval can be very useful for medical practice, medical education, and research. (<i>JAMA</i>1985;254:2768-2774)
From the National Institutes of Health
Authors: James B. Wyngaarden
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Rapidly progressive glomerulonephritis superimposed on diabetic glomerulosclerosis. Recognition and treatment
Authors: S. A. Carstens
Journal: JAMA (1982)

Two patients with long-standing diabetes mellitus and diabetic retinopathy were evaluated for declining renal function and heavy albuminuria. Initially, diabetic glomerulosclerosis was suspected as the cause of progressive glomerulopathy. However, in both patients the rate of loss of glomerular filtration rate was greater than that usually seen in diabetic glomerulosclerosis, and the urine sediment contained many RBC casts. These findings led to renal biopsy, which demonstrated crescentic glomerulonephritis superimposed on diabetic glomerulopathy. Both patients were treated with prednisone and cyclophosphamide and both experienced substantial improvement in renal function. These experiences demonstrate the importance of searching for evidence of a superimposed treatable glomerulopathy in the diabetic patient with glomerulopathy and advancing renal insufficiency. (<i>JAMA</i>1982;247:1453-1457)
Fourth Annual Symposium on Diagnostic Imaging
Journal: JNCI Journal of the National Cancer Institute (1983)

Journal Article Fourth Annual Symposium on Diagnostic Imaging Get access JNCI: Journal of the National Cancer Institute, Volume 70, Issue 5, May 1983, Page 988, https://doi.org/10.1093/jnci/70.5.988-c Published: 01 May 1983
Editorial: Why do we let dogs foul our streets?
Journal: BMJ (1976)

Disseminated intravascular coagulation (DIC) is an important feature of pre-eclampsia and eclampsia, but its correction with a low-dose heparin regimen has not been reported to reduce the incidence of hypertension, proteinuria, or oedema.12Since, however, convulsions may be a manifestation of rapid DIC,'3 heparin treatment in severe pre-eclampsia may prevent their onset; but in eclampsia cerebral haemorrhage is a serious hazard and anticoagulant therapy would be highly dangerous.Despite the reductiorn in the maternal mortality rate, the perinatal mortality rate remains about 15%, usually as a result of prematurity.Future progress will depend on the more efficient detection and treatment of pre-eclampsia, so enabling pregnancy to remain uninterrupted for longer, even in severe cases.
Streptococcal pharyngitis and acute rheumatic fever in Rhode Island
Authors: S. D. Holmberg
Journal: JAMA (1983)

A comprehensive survey of physicians, laboratories, and hospital records in Rhode Island showed that more than 157,000 throat cultures for a population of 930,000 people were done in 1980. Eighty-seven percent of primary care physicians prescribed antibiotic therapy before culture results were known, and almost 40% continued antibiotic therapy for ten days regardless of culture results. The throat culture positivity rate for β-hemolytic<i>Streptococcus</i>was 17% statewide in 1980. Only three definite and seven possible cases of acute rheumatic fever were identified by hospital chart reviews and a physician survey covering the five years 1976 through 1980. Current throat culture practices probably have little influence on treatment of streptococcal pharyngitis and control of rheumatic fever in the state. (<i>JAMA</i>1983;250:2307-2312)
Investigations of Factors Influencing Exposure and Response to Lead, Mercury, and Cadmium in Man and in Animals
Authors: Harry A. Roels, Jean-Pierre Buchet, Alfred Bernard, Gerard Hubermont, Robert R. Lauwerys, Pierre Masson
Journal: Environmental Health Perspectives (1978)

The susceptibility of the heme biosynthetic pathway to lead, as reflected by increased free erythrocyte porphyrin (FEP) concentration, is in humans as well as in rats in the order of young greater than or equal to female greater than male. The difference between adult male and female rats can be explained at least partially by the interaction of estradiol and progesterone with the FEP response to lead; the hormonal influence on FEP does not seem to be mediated through changes in plasma iron. The classical "tubular type" proteinuria in workers chronically exposed to cadmium has two not necessarily concomitant components, namely, a tubular type and a glomerular type component characterized by increased excretion of low and high molecular weight proteins, respectivley. No synergistic effect of cadmium and lead on the proteinuria of workers simultaneously exposed to both metals was observed. Mercury (most likely methylmercury) is freely transferred from the mother to the fetus; there is only a slight placental barrier for lead and a rather strong one for cadmium. Compared to maternal blood, placenta does not accumulate lead or mercury but concentrates cadmium about 10-fold.
Tenth Annual Report of the State Board of Health and Vital Statistics of the Commonwealth of Pennsylvania for the year 1894.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Highlights
Journal: JAMA Oncology (2017)

In Li-Fraumeni syndrome, a germline TP53 mutation predisposes carriers to multiple types of cancers.An effective way to screen them for early-stage cancers is needed.Ballinger et al performed a meta-analysis of 578 screening participants showing that whole-body magnetic resonance imaging (MRI) for screening patients with Li-Fraumeni syndrome is feasible.Of 42 cancers identified, 35 were treated with curative intent.Long-term studies will need to determine whether whole-body MRI screening increases patient lifespan, but early results seem promising.Asdahl et al provide an Invited Commentary.
The Dyslipidoses
Authors: Edward Bigg
Journal: JAMA (1961)

The increasing interest in disturbances of lipid metabolism (designated by Fleischmajer as "the dyslipidoses") makes this book particularly timely. Although it would appear unusual for such a work to emanate from a department of dermatology, the author rightly points out that historically the earliest descriptions of altered fat metabolism were contributed by those observing skin manifestations of these diseases. Beginning with a remarkably clear succinct survey of the biochemistry and metabolism of lipids, the author proceeds to a description of the cutaneous and tendon xanthomas and thereupon to an interesting classification of the dyslipidoses based on biochemical and clinical grounds. This is followed by chapter length discussions of the various diseases and syndromes listed in the classification. A rewarding aspect is the attempt to integrate our known histochemical, physiologic, biochemical, and genetic knowledge with clinical observations and treatment of the diseases described. Dermatologic manifestations are perhaps overemphasized in a work
STATE SCIENTIFIC AID TO CRIMINAL JUSTICE
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Decreased secondary hyperparathyroidism in diabetic patients receiving hemodialysis
Authors: F. Vincenti
Journal: JAMA (1981)

Biochemical and bone scintigraphic studies were performed in nondiabetic and diabetic patients receiving hemodialysis at the time of kidney transplantation to assess the degree of secondary hyperparathyroidism. Despite lower serum calcium concentrations, diabetic patients had significantly lower parathyroid hormone (PTH) levels than nondiabetic patients. In addition, diabetic patients had lower graded total-skeletal scintigraphic scores than nondiabetic patients. The PTH levels showed positive correlations with bone scan scores and with alkaline phosphatase in nondiabetic patients but not in diabetic patients. Avascular necrosis occurred in 17% of nondiabetic patients and in only 2% of diabetic patients. Patients with avascular necrosis had significantly higher PTH levels than patients without avascular necrosis. Diabetes mellitus seems to confer a protective effect from the skeletal manifestations of secondary hyperparathyroidism, including avascular necrosis. (<i>JAMA</i>1981;245:930-933)
Newly licensed hepatitis B vaccine. Known safety and unknown risks
Authors: R. J. Gerety
Journal: JAMA (1983)

THE RECENTLY licensed subunit hepatitis B vaccine (HEPATAVAX-B) is unique among vaccines in that it is manufactured solely from human plasma obtained from asymptomatic individuals with chronic hepatitis B. Plasma from donors selected for manufacturing this vaccine contains high concentrations of noninfectious hepatitis B surface antigen (HBsAg) particles and lower concentrations of infectious hepatitis B virus (HBV). The ratio of HBsAg to HBV can be as great as 10,000:1.<sup>1</sup>From the starting plasma, 22-nm spherical HBsAg particles are separated from HBV by ultracentrifugation. The 22-nm particles are then further purified by digestion with pepsin followed by the addition of 8M urea. Finally, the vaccine is treated with formaldehyde. <h3>Vaccine Plasma Donors</h3> Vaccine plasma donors are selected for their high titers of HBsAg. By federal regulation, they must be asymptomatic and in apparent good health.<sup>2</sup>They must meet all federal requirements for acceptable plasmapheresis donors, except that their serum
ACKNOWLEDGING REPRINTS
Authors: None H. C.
Journal: JAMA (1931)

<h3>To the Editor:</h3> —For the first time in my life I have done the particular kind of thing I am about to describe and in view of what has happened my New England conscience pricks me. The "particular kind of thing" to which I refer was to order as many as 750 reprints of a recent article and to request the publishers to send them out to the addresses I submitted—"With the author's compliments." The addresses were to be found in certain society-membership lists obtainable in any medical library. Now I have never heretofore ventured to order more than a modest number of reprints of any paper, and though I would perhaps be glad to have a few copies of some ancient ones that have run out, this is far outbalanced by the apparent impossibility of getting rid of great bundles of others which encompass and encumber me and which
Infantile diarrhea
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The diagnosis and management of aortic dissection
Authors: E S Crawford
Journal: JAMA (1990)

Aortic dissection is a severe disease. Most untreated patients with types I and II (proximal) dissection and over half of those with type III (distal) dissection die within 1 year. Most of the deaths occur within 2 weeks and are caused by rupture, aortic insufficiency, and branch vessel obstruction. Aortic dissection is suspected in patients with anterior chest and back pain that progresses downward. Diagnosis is confirmed by computed tomography, aortography, or echocardiography. Appropriate medical treatment and corrective surgery, including total aortic replacement, performed in the acute and chronic stages, are now successful in over 90% of the cases; long-term results of treatment are steadily improving and are expected to exceed 50% at 10 years. The keys to a successful outcome are being aware of the symptoms of dissection, early diagnosis, and prompt application of appropriate treatment; diligent follow-up includes controlling blood pressure, decreasing the velocity of left ventricular contraction, monitoring the size of the residual aorta, and taking appropriate action if redissection, aneurysmal formation, or rupture occurs.
Diastrophic Dwarfism
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Haemorrhagic Diatheses
Authors: M. C. G. Israels
Journal: BMJ (1970)

Thank you for your interest in spreading the word about The BMJ.NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Username * Your Email * Send To * You are going to email the following Haemorrhagic Diatheses Your Personal Message CAPTCHA This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Book Listings
Journal: Annals of Internal Medicine (2002)

Book Listings18 June 2002Book ListingsSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-136-12-200206180-00004 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail CardiologyAuscultation Skills: Breath and Heart Sounds2nd edition. Springhouse. 268 pages. Springhouse, PA: Springhouse Corporation; 2002. $50.00. ISBN 1582551588. Order phone 800-588-7738.Cardiac Arrhythmias 2001A Raviele, ed. 657 pages. New York: Springer-Verlag; 2002. $109.00. ISBN 8847001609. Order phone 800-777-4643.Cardiology: Current PerspectivesG Jackson, ed. 404 pages. Philadelphia: Taylor & Francis; 2002. $99.00. ISBN 185317629X. Order phone 800-821-8312.Catheter Ablation of Arrhythmias2nd edition. DP Zipes and M Haissaguerre, eds. 432 pages. Armonk, NY: Futura; 2002. $98.00. ISBN 0879934980. Order phone 800-877-8761.Congenital Heart Disease in the AdultWM Gersony and MS Rosenbaum. 304 pages. New York: McGraw-Hill; 2002. $99.00. ISBN 0070329095. Order ... Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 18 June 2002Volume 136, Issue 12Page: I-38-I-42KeywordsComputed axial tomography ePublished: 18 June 2002 Issue Published: 18 June 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...