tbuckley/cabot-search huggingface dataset:
Announcement: Spotlight Issue on Mechanisms of Angiogenesis and Remodeling of the Microvasculature
Authors: Alain Tedgui, Bernard Lévy, Jean-Sébastien Silvestre
Journal: Cardiovascular Research (2007)

A Spotlight Issue on mechanisms of angiogenesis and remodeling of the microvasculature is scheduled to appear in May, 2008, that will address the cellular and molecular mechanisms involved in new vessel growth in both physiological and pathological settings.Identification and definition of these mechanisms should lead to the development of therapeutic strategies designed to promote revascularization in patients with ischemic diseases.Preliminary topics of invited review articles related to the angiogenesis and the microvasculature include:
IL-5 links adaptive and natural immunity in reducing atherosclerotic disease
Authors: A. Daugherty
Journal: Journal of Clinical Investigation (2004)

Oxidized LDL induces changes in several facets of the immune system, although the relationships between these facets and their contributions to atherogenesis have yet to be fully elucidated. A report in this issue of the JCI provides a novel demonstration of the adaptive immune system influencing the production of natural antibodies. The results demonstrate that injection of malondialdehyde-modified LDL promotes a Th2 response that in turn increases the titers of the natural antibody T15/EO6, which recognizes the oxidized phospholipid POVPC. Atherosclerotic lesion size in LDL receptor–deficient mice is reduced as a consequence of the increase in natural antibody titers, and IL-5 is identified as the link between the adaptive and natural immune systems.
Advantages of Computerized Psychiatric History Taking
Authors: John H. Greist
Journal: JAMA (1972)

<h3>To the Editor.—</h3> Two EDITORIALS, "Patient History Under Scrutiny" and "Medical Care: Acceptability and Adequacy" question whether increasingly complex and impersonal health delivery "systems" can sustain a sufficiently trusting patient-physician relationship to encourage the patient to reveal his problems (219:1208, 1972). The dilemma is this: Can a patient-physician communication be standardized to the point where "human frailties" (especially those that distort or overlook problems) can be minimized without making the process so impersonal that the relationship breaks down and communication becomes impaired? This ultimately raises questions of the usefulness and the humanity of indirect methods of information-getting such as questionnaires and structured interviews. In communication, it is important to distinguish the frailties of the human participants from the frailties inherent in the communication process itself. Humans may well be stronger than the communication bridge between them. Rejection of impersonal communication methods on the grounds of inhumanity may lose sight of
HIV Infection as Leading Cause of Death Among Young Adults in US Cities and States
Authors: Richard M. Selik
Journal: JAMA (1993)

<h3>Objective.</h3> —To describe the extent to which human immunodeficiency virus (HIV) infection has become the leading cause of death among young adults (25 to 44 years of age) in US states and cities of at least 100000 population. <h3>Design.</h3> —Analysis of underlying causes of death using national vital statistics for 1990 by state and city. Deaths caused by HIV were defined as those with underlying cause assigned a code number of 042,043, or 044, as established by the National Center for Health Statistics. <h3>Results.</h3> —Infection with HIV was the leading cause of death among young men in five states, causing 29% of their deaths in New York, 28% in New Jersey, 24% in California and Florida, and 16% in Massachusetts. Among young women, HIV was not the leading cause of death in any state. Among young men, HIV infection was the leading cause of death in 64 cities, with the proportion of deaths due to HIV ranging from 16% in Bridgeport, Conn, to 61% in San Francisco, Calif. Among young women, HIV infection was the leading cause of death in nine cities, with the proportion of deaths due to HIV ranging from 15% in Baltimore, Md, to 43% in Newark, NJ. <h3>Conclusion.</h3> —In many US communities, HIV infection is the leading cause of death among young men and women, causing a large proportion of deaths in this age group. (<i>JAMA</i>. 1993;269:2991-2994)
BELA SCHICK
Authors: I. J. Wolf
Journal: JAMA (1968)

On December 6,1967, Bela Schick died at Mount Sinai Hospital, New York. He was past his ninetieth year, and had lived in the United States for the last half of his life. Dr. Bela Schick was born on July 16, 1877, at Boglar on the shore of Lake Balaton, Hungary. Contemporary with his birth was the flare-up of the Indian Wars in this country following the Custer massacre in Wyoming. In Europe another war began between Russia and Turkey. The British entered Afghanistan and occupied the island of Cyprus. Guided and influenced by his physician-granduncle, Schick entered the field of medicine. He took his medical degree at the Karl Franz University in Graz in 1900, and after graduation began work with Escherich, whom he subsequently followed to Vienna. When the latter was appointed Professor of Children's Diseases there, Schick worked alongside von Pirquet as Escherich's assistant, leading a life of
Giardiasis
Authors: Martin S. Wolfe
Journal: JAMA (1975)

The recent near-epidemic incidence of<i>Giardia lamblia</i>infection in visitors to the Soviet Union illustrates the importance of this intestinal flagellate as a cause of diarrhea in travelers worldwide. Clinical states range from the asymptomatic cyst-passing stage, to the chronic or subacute stage mimicking gallbladder or ulcer disease, to the transient or, rarer, persistent acute stage with steatorrhea and substantial weight loss. Symptoms may be related to IgA deficiency. Secondary lactose intolerance may follow eradication of the parasite. Diagnosis is usually based on repeated stool examinations or examination of duodenal contents. Quinacrine hydrochloride is the most effective treatment, but metronidazole and furazolidone are also useful. Contaminated water is the most likely source of infection. (<i>JAMA</i>233:1362-1365, 1975)
Penicillin-resistant Bacteroides melaninogenicus
Authors: W. A. Agger
Journal: JAMA (1982)

<h3>To the Editor.—</h3> The choice of antimicrobial therapy for anaerobic lung infections remains controversial. These infections usually result from penicillin-sensitive oral flora. However, isolates of penicillin-resistant<i>Bacteroides fragilis</i>and<i>Bacteroides melaninogenicus</i>from such cases have been reported.<sup>1</sup>Despite these resistant organisms, several reports have indicated that such infections may respond as well to penicillin as to clindamycin or other antimicrobial drugs directed against the penicillin-resistant species.<sup>2</sup> We recently treated a cavitating anaerobic pneumonia that did not respond to penicillin or to ampicillin in one of our patients. Clinical response occurred only after administration of clindamycin phosphate was begun. <h3>Report of a Case.—</h3> A 68-year-old diabetic man had development of rigors, fever, and a productive cough. After seven days of illness, a chest roentgenogram disclosed a right lower lobe pneumonia. After hospitalization, intravenous (IV) administration of penicillin G sodium, 600,000 units every six hours for four days, followed by
Psychogenic Deafness
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transactions of the Academy of Stomatology.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Early detection of breast cancer. Council on Scientific Affairs
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of physical examination skills. Reliability of faculty observers and patient instructors
Authors: D. L. Elliot
Journal: JAMA (1987)

Effective teaching of physical examination skills requires an evaluation system that can identify trainees who need further instruction. To study the evaluation of physical examination skills by faculty observers and patient instructors, the reliability of their observation of medical students performing a general physical examination was measured. Faculty observers did not reliably evaluate 32% of examination skills. Faculty agreement was lowest when observing components of the head, neck, and abdominal examinations. Patient instructors, with limited faculty training, reliably evaluated 83% of those skills that were reliably assessed by the faculty. These findings demonstrate limitations in the current methods of evaluating performance and point out the need to examine systems of trainee assessment. (<i>JAMA</i>1987;258:3405-3408)
<i>Announcement</i>: U.S. Antibiotic Awareness Week — November 13–19, 2017
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

U.S. Antibiotic Awareness Week is an annual observance to raise awareness about antibiotic resistance and the importance of appropriate antibiotic prescribing and use.This year's observance coincides with the release of CDC's updated educational initiative "Be Antibiotics Aware: Smart Use, Best Care," and aims to engage health care professionals, advocacy groups, for-profit companies, state and local health departments, professional societies, the general public, the media, and others in efforts to improve antibiotic prescribing and use across all health care settings.This observance coincides with the World Health Organization's World Antibiotic Awareness Week and European Antibiotic Awareness Day on November 18.Antibiotics save lives.When a patient needs antibiotics, the benefits outweigh the risks for side effects or antibiotic resistance.However, antibiotic resistance is one of the most urgent threats to the public's health.Each year in the United States, approximately 2 million persons are infected with antibiotic-resistant bacteria, and approximately 23,000 die as a result.*Helping health care professionals improve the way they prescribe antibiotics and improving the way patients take antibiotics helps keep everyone healthy now, helps fight antibiotic resistance, and ensures that lifesaving antibiotics will be available for future generations.Preventing antibiotic-resistant infections and protecting the nation's health by improving antibiotic prescribing and use is a CDC priority.Additional information about "Be Antibiotics Aware" during U.
Anne Appleton
Authors: A. Appleton
Journal: BMJ (2015)

Background: Capecitabine is an oral prodrug of flurouracil with broad activity against various malignancies. We explored its tolerance and preliminary efficacy when given together with cisplatin in a phase I/II study preferentially enrolling gastric cancer patients. Patients and Methods: The study was a 3+3 dose escalation design and at the recommended phase II dose it included an expanded cohort of patients with upper gastrointestinal cancer. The dose of cisplatin was escalated from 40 to 50 mg/m<sup>2</sup> on day 1, and capecitabine of 2,500 mg/m<sup>2</sup>/day starting on day 2, was escalated from 5 days to 10 and then to 14 days, with the cycle repeated every 21 days. Prolonged maintenance with capecitabine was offered to selected patients completing three to six cycles. Results: A total of 34 patients were enrolled, and 27 patients were also evaluable for response. Dose limiting toxicities were palmar plantar erythrodyesthesia (PPE) and diarrhea; grade 3 and 4 neutropenia occurred in 8.8% and grade 3 PPE in 5.9%, while the most common grade 1-2 toxicities were anemia, neutropenia, fatigue and PPE (11.7% each). There were no treatment related deaths. With cisplatin at 40-50 mg/m<sup>2</sup> day 1 and capecitabine at 2,500 mg/m<sup>2</sup>/day for 5 -14 days every 21 days, 18 patients with gastric cancer were treated and 7 had partial responses. Conclusion: A regimen of capecitabine and cisplatin at the doses and schedules explored was safe and active in patients with gastric cancer. Moreover, a 6-month administration of adjuvant capecitabine proved feasible, yielding favorable results after treatment completion and surgery, and should be investigated further.
Inadequate functional health literacy
Authors: R. L. Gottesman
Journal: JAMA (1996)

<h3>In Reply.</h3> —Drs Gottesman and Kelly raise an interesting question about the root causes of low literacy. We agree that some people who have low literacy skills may have specific learning disabilities (eg, dyslexia) that prevented them from learning to read. However, we believe the vast majority of the problem stems from lack of access to education or poor-quality education during critical developmental periods. The higher prevalence of low literacy among older adults and Spanish-speaking patients, many of whom were unable to go to school or attended schools with very poor facilities, supports this explanation and argues against learning disabilities as the dominant cause. Labeling low literacy as a learning disability is also extremely dangerous because many children from racial and ethnic minorities in the United States have been cast aside into "handicapped" classes because their language abilities were behind their peers. Nevertheless, we agree that many patients with low
THE DEADLY CIGARETTE.
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pituitary Cytokine and Growth Factor Expression and Action
Authors: D. Ray
Journal: Endocrine Reviews (1997)

Introduction A. Hormone secretion 1. Tier 2. Tier II 3. Tier III II.Cytokines and growth factors A. Interleukins 1. IL-1, ␣ and ␤ 2. IL-2 3. IL-6 B. Leukemia-inhibitory factor (LIF) C. Macrophage migration inhibitory factor (MIF) D. Epidermal growth factor (EGF) E. Transforming growth factor-␣ (TGF␣) F. Fibroblast growth factors (FGFs) 1. FGF-2 2. Chondrocyte growth factor (CGF) 3. FGF-4 G. Nerve growth factor (NGF
Heroin pulmonary edema
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Injuries to JFK
Authors: David W. Mantik
Journal: JAMA (1992)

<h3>To the Editor.</h3> —The congruent skull and scalp defect described by Dr Humes was 400% larger in area than that reported in Dallas. The Dallas wound was more occipital; Humes described a chiefly parietal wound. Contemporary sketches prepared from the two sources are remarkably different. Mr Breo<sup>1,2</sup>quotes Dr M. T. "Pepper" Jenkins as retracting his 1963 viewing of the cerebellum in Dallas. In fact, Jenkins repeated this for the Warren Commission hearings. Cerebellar tissue was also seen by Drs William Kent Clark, Charles Baxter, James Carrico, Robert McClelland, and reported by Dr Malcolm Perry to the House Select Committee on Assassinations. The entrance wound, according to Humes, was near the external occipital protuberance. The Clark panel,<sup>3</sup>however, located it 100 mm (sic) superior to this site, ie, near the cowlick area. This 10-cm discrepancy was also confirmed by Dr Baden before the House Select Committee on Assassinations.
DO BACTERIA SUFFER FROM INFECTIOUS DISEASES?
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Colovesical Fistula
Authors: Akbar N Ashrafi, Rene Sotelo
Journal: New England Journal of Medicine (2019)

A 72-year-old woman presented with a 2-week history of passing gas in her urine. Cystoscopy revealed an area of edematous bladder mucosa with a central orifice that extruded gas and feculent material (shown in a video), and a diagnosis of a colovesical fistula was made.