tbuckley/cabot-search huggingface dataset:
A national survey of public health officers' interactions with the media
Authors: G. A. Gellert
Journal: JAMA (1994)

<h3>Objectives.</h3> —To assess the perceptions, practices, and needs of state and local health officers with respect to professional interactions with the media. <h3>Design.</h3> —A survey of 759 public health officers (56 state and 703 local) on jurisdiction demographics, frequency of media interactions, agency process for media contacts, provision and need for media training, and character of media relations. <h3>Participants.</h3> —Fifty-two state health officers and 568 US local health officers responded, for a survey response rate of 82%. <h3>Results.</h3> —Media reporting was perceived as accurate 52% to 73% of the time, although reporters were seen as needing improved technical and scientific knowledge. Media were used frequently as a component of health education. State health jurisdictions were more likely than local jurisdictions to have a media protocol and designated media contact, to internally review media releases, to interact regularly with media, and to provide staff training on media relations. Media interaction time comprised print media (63%), television (19%), and radio (17%). One third of the health officers found media relations adversarial, but most held a positive overall view of the media. Favorable evaluation of the media was associated with high frequency of media contact, high perceived accuracy of reporting, and presence of an institutional media protocol. <h3>Conclusions.</h3> —While health officers evaluated media favorably, problem areas were identified where mutual education could improve the accuracy and value of media reporting on health issues. Training capacity for both professions should be developed to increase the effectiveness of public health in media relations. (<i>JAMA</i>. 1994;271:1285-1289)
Stress-induced cortisol release in hypothalamic hypoadrenalism
Authors: A. R. Glass
Journal: JAMA (1979)

A 52-year-old woman experienced hypoadrenalism (mean 8 AM plasma cortisol level, 3.7 μg/dL) after hypothalamic surgery and radiotherapy for craniopharyngioma. Despite low plasma adrenocorticotropic hormone levels (less than 25 pg/mL), absent diurnal variation of the plasma cortisol level, and subnormal urinary 17-hydroxycorticosteroid response to metyrapone, she had normal plasma cortisol responses to insulin-induced hypoglycemia and to administration of vasopressin or synthetic adrenocorticotropic hormone. Stress-induced cortisol release may be preserved despite notable abnormalities in regulation of cortisol secretion by diurnal and feedback-mediated mechanisms. (<i>JAMA</i>241:1612-1613, 1979)
Abstract 2341: Indoleamine 2,3 dioxegenase 1 (IDO1) and T-cell infiltration in esophageal cancer
Authors: Ari J. Rosenberg, Derek A. Wainwright, Angela J. Fought, Lijie Zhai, Kristen Lauing, Victoria M. Villaflor
Journal: Cancer Research (2019)

Abstract Background: Immune checkpoint blockade is emerging as an important immunotherapeutic strategy in esophageal cancer, yet response rates remain low. IDO1 is a rate-limiting immunosuppressive enzyme that may contribute to resistance to immune checkpoint blockade in human cancer, and may be an important immunotherapeutic target. The expression pattern of IDO1 across esophageal cancer histologies remains poorly understood. Here, we utilize immunohistochemistry to characterize the expression pattern and relevance of IDO1 in esophageal cancer. Methods: Tumor microarray containing samples of surgically resected esophageal carcinoma and normal esophageal tissue were stained for IDO1 and CD3ϵ (marker of T-cell infiltration). Demographic and staging data were collected. Light microscopic immunoscoring analysis was performed. Correlations were analyzed using Fisher’s exact test. Results: 192 samples were assessed (180 esophageal carcinoma, 12 normal esophageal tissue.) Median age was 60 years (range 34-78). 69.3% of patients were male. Of the 180 esophageal carcinoma samples, 150 (83.3%) squamous cell carcinoma, 16 (8.9%) adenocarcinoma, 13 (7.2%) small cell carcinoma, 7 (3.9%) undifferentiated carcinoma, 2 (1.1%) carcinoid, 2 (1.1%) adenosquamous carcinoma, and 2 (1.1%) adenoid cystic carcinoma. IDO1 was positive in 81 samples (45.0%) overall with 52.0% in squamous cell carcinoma and 46.7% in adenocarcinoma. Positive IDO1 was associated with higher stage and nodal positivity (P=0.04). T-cell infiltration in esophageal carcinoma specimens was present in 133 samples (73.9%). IDO1 positivity correlated with increased T-cell infiltration (P&amp;lt;0.01). Conclusions: Here our study suggests that expression of IDO1 is positive in almost half of esophageal tumors, and is associated with T-cell infiltration. Additionally, positive IDO1 was associated with higher likelihood of nodal involvement and more advanced stage. These data suggest that IDO1 may play a role in adaptive immune resistance in T-cell inflamed tumors, and that incorporating IDO1 inhibition into an immunotherapeutic strategy in esophageal cancer may enhance T-cell mediated anti-tumor effect. Citation Format: Ari J. Rosenberg, Derek A. Wainwright, Angela J. Fought, Lijie Zhai, Kristen Lauing, Victoria M. Villaflor. Indoleamine 2,3 dioxegenase 1 (IDO1) and T-cell infiltration in esophageal cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 2341.
Appendicitis.
Authors: Robert T. Morris
Journal: JAMA (1898)

New York City, May 8, 1898. <h3>To the Editor:</h3> —There have been no responses in theJournalin answer to my request in a February number, asking correspondents to oppose the idea that appendicitis cases require operation as soon as the diagnosis has been made. Several references to my request have been made in other medical publications, however, and one which appeared as an editorial in the March number of the<i>Texas Medical News</i>covers the ground of the oppositionists so well that I have asked the editor of the<i>News</i>to allow me to answer in theJournal, because that was the medium which I chose originally for the discussion. (I have italicized the parts of the republished<i>News</i>editorial which are answered<i>seriatim</i>.) <h3>EDITORIAL ARTICLE.</h3> "There are always to be found men occupying<i>extreme positions</i>in every profession. This is especially so in medicine and surgery. Men, too,
El factor emocional en la etiopatogenia de la enfermedad de Basedow. El mecanismo causal analizado en 24 casos: Conclusiones, patogenicas, terapeuticas, pronosticas y profilacticas
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
5. Facilitating Behavior Change and Well-being to Improve Health Outcomes:<i>Standards of Medical Care in Diabetes—2020</i>
Journal: Diabetes Care (2019)

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes the ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, a multidisciplinary expert committee (https://doi.org/10.2337/dc20-SPPC), are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA’s clinical practice recommendations, please refer to the Standards of Care Introduction (https://doi.org/10.2337/dc20-SINT). Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC.
Interstitial high dose rate (HDR) brachytherapy for early stage breast cancer
Authors: T. Neumann, P. Anderson, R. Mark, M. Nair
Journal: Journal of Clinical Oncology (2005)

819 Background: External Beam Radiation Therapy (EBRT) has been the standard of care for breast conservation radiation therapy. Recent data indicates that Interstitial Implant and High Dose Rate (HDR) radiation afterloading compares very favorably to EBRT in selected patients. Methods: Patients with Tis, T1, and T2 tumors measuring ≤ 3 cm, negative surgical margins, and negative axillary lymph nodes were judged to be candidates for Interstitial Implant. Subsequently, patients who had, or were scheduled to receive anthracycine based Chemotherapy were excluded. Results: Between 2000 and 2004, 94 patients underwent Interstitial HDR Implant under Stereotactic Mammographic guidance with conscious sedation and local anesthesia. The implants were placed using a customized Lucite Template utilizing from 3 to 4 planes, and 8 to 26 needles. Catheters were subsequently threaded thru the needles, and the needles removed. Catheter spacing was 1.5 cm. Radiation Treatment planning was performed using CT Scanning and the Plato System. Treatment volumes ranged from 25 cm3 to 359 cm3. HDR treatment was given using the Nucletron afterloading system. The breast implant volume received 4,000 cGy in 10 fractions prescribed to the 100% Isodose line, given BID over 5 days. The procedure was well tolerated. No patient required hospital admission. With a median follow-up 35 months (range 6–56 months), local recurrence occurred in 2.1% (2/94). Cosmetic results were good to excellent in 86.1% (81/94) of the patients. Wound healing complications developed in 8.5% (8/94). Three of these patients had received anthracycline based Chemotherapy. The other five had large (> 200 cm3) implant volumes. Two patients healed after 6 months of conservative treatment. Surgery was required in six patients who developed fat necrosis. Conclusions: Breast Conservation radiation therapy utilizing Interstitial HDR Implant appears to yield local recurrence rates and cosmetic results which compare favorably to EBRT in selected patients. Longer follow-up is needed. Treatment with anthracycline based Chemotherapy and large (> 200 cm3) implant volumes appear to be relative contraindications to Interstitial HDR Implant. No significant financial relationships to disclose.
MILK CALCIUM FOR CHILDREN
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
J. M. MATHEWS, PRESIDENT.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ERADICATION OF YELLOW FEVER IN HAVANA.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CHEMISTRY IN RELATION TO THE FOOD INDUSTRY
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Preventive medicine. Components or proponents?
Authors: H. J. Magnuson
Journal: JAMA (1966)

The Section on Preventive Medicine is the American Medical Association's home of those special interests in medicine that have been identified under the American Board of Preventive Medicine —currently public health, aerospace medicine, occupational medicine, and general preventive medicine. Discontent with the term "preventive medicine," with the specialty groupings under preventive medicine, and with the emphasis of various residency programs is frequently expressed. Is this discontent purely one of semantics or are there differences in goals and purposes that preclude a unified approach? If we could agree on goals and purposes, are the means of attaining these goals so diverse that the means themselves determine widely different professional capabilities? These are issues which can be reviewed superficially at best in the space allotted. I believe examination of the major components will identify more that unite than divide us and that the jobs to be done in the years ahead call
Medical Research
Authors: John T. Flynn
Journal: JAMA (1981)

<h3>To the Editor.—</h3> The article on the cost of not doing medical research by William C. Gibson, MD, DPhil, FRCP (1980;244:1817), eloquently identifies the enormous savings in the cost of medical care that medical research has generated, but such a message is lost on our political leaders and representatives who have long since spent those savings in other directions and currently tremble on the edge of governmental insolvency. In addition, these same leaders are plagued by a confusion of realistic doubts about the escalating costs stemming from rapid advances in medical technology, particularly where in so many instances it does not advance the basic understanding of disease nor favorably influence morbidity or mortality. In addition to current financial discouragements, both the basic medical scientist and his clinical research colleague live with the threat to their individual pursuits posed by others' discoveries. In addition, there are the preoccupations with departmental administrative
Deposit and Mobility of Cadmium in a Marsh-Cove Ecosystem and the Relation to Cadmium Concentration in Biota
Authors: Theo. J. Kneip, Robert E. Hazen
Journal: Environmental Health Perspectives (1979)

The study reported here presents the results of an investigation of a marsh-cove ecosystem heavily contaminated by cadmium. The most contaminated aquatic sediments were dredged in 1972-73, but the resuspension of the sediments and recycle of water from the dredge spoil resulted in reestablishment of a large contaminated sediment bed with concentrations very similar to those observed before dredging. The stability of the sediment concentrations and shallow depth of the cadmium in the sediments indicate that the deposit is relatively stable in agreement with the expectations based on the water chemistry of the system. Uptake does occur in both marsh and aquatic plants and all species of animals tested. Significantly elevated concentrations are observed compared to noncontaminated areas; however, edible portions of most fish do not appear to present a hazard. Crabs appear to present the most likely source of a hazard to humans. This potential hazard is still under investigation. The dredging removed about 5.5 MT of cadmium, about one-fourth of that originally estimated to be present, but twice that amount is found to be in the cove sediments 3 to 4 years after dredging. No appreciable improvement in the ecosystem has been made, and more careful consideration should be given to the need for decontamination and the method of removal of contaminated aquatic sediments in any future case.
Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes
Authors: Yanfeng Wang, Rustem I. Litvinov, Xinsheng Chen, Tami L. Bach, Lurong Lian, Brian G. Petrich, Susan J. Monkley, Yasunori Kanaho, David R. Critchley, Takehiko Sasaki, Morris J. Birnbaum, John W. Weisel, John Hartwig, Charles S. Abrams
Journal: Journal of Clinical Investigation (2008)
Pediatric Nephrology
Authors: M. William Schwartz
Journal: JAMA (1975)

In assembling their first edition of<i>Pediatric Nephrology</i>, Drs Rubin and Barratt brought together in a single volume the knowledge of many leading authorities on renal disease of children. For the most part this effort was a success. The reader can now have, in one volume, most of the latest information on pediatric nephrology. The structure of the book includes the usual format of anatomy, physiology, and metabolism of the kidney. The next sections, dealing with laboratory evaluations, prepare the reader for the discussions of clinical states—maldevelopment, renal failure, nephrotic syndrome, the glomerulopathies, infections, and tubular disorders. Extensive references are included with each chapter. The chapters relating to clinical situations are the strongest features of the book. Rubin's chapter on nephrosis, glomerulonephritis, and urinary tract infection are a pleasant mixture of a personal perspective, from many years in pediatrics, and a well-written review of these topics. The chapters about complement,
Cardiac pacemaker function
Authors: R. S. Pennock
Journal: JAMA (1972)

A transtelephonic system for evaluation of implanted cardiac pacemakers has been developed. Over a 12-month period, 134 units were tested. Of the 28 pacemaker replacements, 26 were due to battery failure and were predicted. All 26 patients were electively admitted for pacemaker replacement. Catheter electrode failure occurred in two patients and was diagnosed via the transtelephonic system. This system provides a method for prolonging life expectancy of permanent cardiac pacemakers as well as drastically reducing emergency admissions for unpredicted failure.
Principles of Surgical Care, Shock and Other Problems
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal