tbuckley/cabot-search huggingface dataset:
Death delusion
Authors: Anders Helldén, Ingegerd Odar-Cederlöf, Kajsa Larsson, Ingela Fehrman-Ekholm, Thomas Lindén
Journal: BMJ (2007)

Objective To assess the evidence for a genetic basis to magic.Design Literature review.Setting Harry Potter novels of J K Rowling.Participants Muggles, witches, wizards, and squibs.Interventions Limited.Main outcome measures Family and twin studies, magical ability, and specific magical skills.Results Magic shows strong evidence of heritability, with familial aggregation and concordance in twins.Evidence suggests magical ability to be a quantitative trait.Specific magical skills, notably being able to speak to snakes, predict the future, and change hair colour, all seem heritable.Conclusions A multilocus model with a dominant gene for magic might exist, controlled epistatically by one or more loci, possibly recessive in nature.Magical enhancers regulating gene expression may be involved, combined with mutations at specific genes implicated in speech and hair colour such as FOXP2 and MCR1. IntroductIonGenetic factors that underlie traits such as height 1 and weight 2 are currently under scrutiny using genome wide association methods, yet the detection of genes predisposing to magic has been given relatively short shrift.Using the books by J K Rowling about Harry Potter, a schoolboy wizard, to gain an insight into humans with magical abilities, one study suggested that magic is the result of a single gene. 3This assertion has been contentious, however, with another study questioning whether magic is heritable. 4We assessed the heritability of magic now that the Harry Potter series is complete with the publication of the seventh and final book. 5 According to the Harry Potter books [5][6][7][8][9][10][11] most people in the world are muggles-that is, possess no magical ability-whereas a minority are witches and wizards with magical abilities.Rarely we are introduced to squibs, offspring resulting from the non-transmission of magic within a family with magical abilities.Compared with muggles squibs have some magical ability, as they can see and interact with the magical world.When considering the genetics of magic we need to be able to explain several observations.Firstly,
Dr. Frank Cregor Retires at Indiana
Journal: JAMA (1942)

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Plenary posters 168-197
Authors: S Parry, J Barton, M Welfare, I Mohammed, L Cherkas, S Riley, T Spector, N Trudgill, S Lal, J Mclaughlin, G Giampaolo, G Dockray, A Varro, D Thompson, J Jones, D Kendall, P Millns, C Hawkey, S Dunlop, D Jenkins, R Spiller, L Gregory, L Yaguez, S Coen, E Amaro, S Smale, A Hobson, S Williams, Q Aziz, V Chudleigh, E Brennan, S Tarry, S Myers, S Lewis, G Smith, K Palmer, Z Khan, E Simpson, A Cole, I Macdonald, D Pye, A Austin, J Freeman
Journal: Gut (2002)

Introduction: Previous studies, many uncontrolled, suggest 4 to 32% of people develop irritable bowel syndrome (IBS) after ID.Little information is available on the development of other FGIDs after ID.Aim: To determine if patients with stool culture confirmed bacterial diarrhoea were more likely to develop gut symptoms consistent with a diagnosis of IBS, functional dyspepsia or functional diarrhoea at 3 and 6 month follow up compared with community controls.Methods: A prospective community-based case-control study over one year.Subjects with stool positive bacterial infectious diarrhoea and control subjects from the same primary care practice were invited to participate.The presence or not of IBS, functional dyspepsia or functional diarrhoea was diagnosed at the start and at follow up using self-complete Rome II modular questionnaires.The diagnosis of a baseline FGID excluded subjects from continuing.There were 128 cases and 219 community controls eligible and who consented to participate.Results: At follow up there was a higher incidence of FGIDs in the cases compared with controls, mainly due to a higher incidence of IBS (see table ).There was no difference in the incidence of functional dyspepsia between cases and controls.Conclusions: IBS and functional diarrhoea is diagnosed more frequently in people at three and six-month follow up after an episode of stool positive bacterial diarrhoea compared with community controls despite careful exclusion of people with pre-existing FGIDS and adds further support for the concept of post-infectious IBS.
THE RELATION OF DRESS TO PELVIC DISEASE
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Officers' Guide: A Ready Reference on Customs and Correct Procedures Followed Within the Army Which Pertain to Commissioned Officers
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The association of skin color with blood pressure in US blacks with low socioeconomic status
Authors: M. J. Klag
Journal: JAMA (1991)

To determine the association of skin color, measured by a reflectometer, with blood pressure in US blacks, we studied a community sample of 457 blacks from three US cities. Persons taking antihypertensive medications were excluded. Both systolic and diastolic blood pressure were higher in darker persons and increased by 2 mm Hg for every 1-SD increase in skin darkness. However, the association was dependent on socioeconomic status, whether measured by education or an index consisting of education, occupation, and ethnicity, being present only in persons with lower levels of either indicator. Using multiple linear regression, both systolic and diastolic blood pressure remained significantly associated with darker skin color in the lower levels of socioeconomic status, independent of age, body mass index, and concentrations of blood glucose, serum urea nitrogen, serum uric acid, and urinary sodium and potassium. The association of skin color with blood pressure only in low socioeconomic strata may be due to the lesser ability of such groups to deal with the psychosocial stress associated with darker skin color. However, these findings also are consistent with an interaction between an environmental factor associated with low socioeconomic status and a susceptible gene that has a higher prevalence in persons with darker skin color. (<i>JAMA</i>. 1991;265:599-602)
Neonatal Hirschsprung's Disease: Treatment of Complete Aganglionosis of the Colon by the Duhamel Operation
Journal: JAMA (1963)

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THE PANAMA CANAL COMMISSION'S SANITATION PROBLEM.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The oncology prognosis and informed consent: Presentation of a new model to best inform patients.
Authors: Benjamin Garmezy, Francis P. Worden, Jennifer Blumenthal-Barby
Journal: Journal of Clinical Oncology (2017)

e18286 Background: Receiving a malignant diagnosis is challenging and patients must be properly informed of their prognosis to make the best decisions for themselves and their families. The general population has a low degree of statistical literacy and therefore approximations should be considered favorable. However, given that half of patients desire quantitative data, physicians must provide this information within a context that is relevant and comprehensible. Single-point median survival data is less meaningful for patient decision-making. What is preferable is that physicians give experience-based estimations on how a patient might compare to the ‘average’. Including this information leads to more informed consent and best follows the ethical principle of autonomy. Methods: This is a novel framework for providing a prognosis that builds upon the multiples-of-the-mean model established in 2010 by Kiely, Tattersall, and Stockler. This framework was derived from original ethics research involving patient preferences, statistical comprehension, healthcare communication, and medical decision-making. Results: Graphical representation of Kiely’s model provides an intelligible view of quantitative data and allows for the physician to include an experience-based estimation. Steps: (1) Draw a Horizontal line, (2) Calculate from median survival data by using five multiples: 0.25 (Worst-Case, 10% of patients), 0.5 (Lower-Typical, 25%), 1 (Median, 50%), 2 (Upper-Typical, 75%), and 3 (Best-Case, 90%), (3) Label the chart using simple time points in months or years (4) Draw a circle over the region that best represents the patient’s expectation, (5) Provide the diagram alongside easy-to-understand language that clarifies the meaning of the numerical data with written likelihood of the occurrence, such as “almost no chance”, “not likely”, “even chances”, “likely”, and “fairly confident”. Conclusions: Kiely’s model has proven an accurate estimation in colorectal, castration-resistant prostate, non-small-cell lung, and metastatic breast cancer. A graphical representation should provide physicians an easy tool to strengthen informed consent and better aid their patients in decision-making.
High prevalence of hepatitis C virus infection in patients with B-cell lymphoproliferative disorders in Italy
Authors: Gennaro De Rosa, Maria Luisa Gobbo, Amalia De Renzo, Rosario Notaro, Salvatore Garofalo, Maria Grimaldi, Aurora Apuzzo, Federico Chiurazzi, Marco Picardi, Margherita Matarazzo, Bruno Rotoli
Journal: American Journal of Hematology (1997)
Medicine
Journal: JAMA (2001)

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LETTER FROM NEW YORK.
Authors: None P. B. P.
Journal: JAMA (1889)

(FROM OUR OWN CORRESPONDENT.) Meeting of the New York Academy of Medicine —Paper by Dr. T. Gaillard Thomas, on Mania and Melancholia following Gynecological Operations—Six Cases reported. One of the largest audiences of the season assembled at the first meeting of the Academy of Medicine, in April, to hear a paper by Dr. T. Gaillard Thomas on<i>Acute Mania and Melancholia or Sequelæ of Gynecological Operations</i>. The object of the paper, he said, was to place on record what he thought must be a rather remarkable experience as regards the matters in question. He desired to call attention at the outset to the fact that he did not announce these peculiar and alarming states as complications, or necessarily as results of operative procedure, but merely as sequels, which might or might not, be dependent upon it. Further, in this connection, he wished to disclaim the position that the operations performed
Officials of the Association—1964-1965
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MRI findings in chronic hepatic encephalopathy: Results of a randomized trial comparing transjugular intrahepatic portosystemic shunt and sclerotherapy . (1) Dept. of Gastroenterology, (2) Dept. of Neurology, (3) Dept. of Neuroradiology, (4) Dept. of Psychiatry of the Reprecht-Karls University of Heidelberg, FRG
Journal: Hepatology (1995)
Induction of Arsenite Tolerance and Thermotolerance by Arsenite Occur by Different Mechanisms
Authors: Zaolin Wang, Guoying Hou, Toby G. Rossman
Journal: Environmental Health Perspectives (1994)

Both V79 and As/R28A cells (an arsenite-resistant Chinese hamster V79 cell variant) show increased resistance to toxic concentrations of arsenite after pretreatment with a nontoxic concentration.The induced tolerance can be completely inhibited by actinomycin D or cycloheximide.Pretreatment with a nontoxic heat shock (45°C, 10 min) resulted in a clear increased thermotolerance in both cell lines but failed to induce arsenite tolerance in either cell line.Pretreatment with arsenite induced a thermotolerance in V79 cells but not in As/R28A cells.These results are consistent with a model whereby the signal for induction of arsenite tolerance involves binding of arsenite to a protein effector which is amplified in the As/R28A line, thereby preventing action of arsenite in the regulation of heat shock factor which induces the heat shock response.
BCL6 Is Regulated by p53 through a Response Element Frequently Disrupted in B-Cell Non-Hodgkin’s Lymphoma.
Authors: Ofer Margalit, Hila Amram, Ninette Amariglio, Amos J. Simon, Galit Granot, Neri Minsky, Sigal Shaklai, Avichai Shimoni, Alon Harmelin, David Givol, Mordechai Shohat, Moshe Oren, Gideon Rechavi
Journal: Blood (2005)
The patient with acute diarrhea. An algorithm for diagnosis
Authors: T. K. Satterwhite
Journal: JAMA (1976)

DIARRHEAL illness is one of the most common disorders of man. In most instances, enteric infection is self-limiting, but in some cases, appropriate specific therapy can shorten the illness, and in a smaller number, similar treatment may be lifesaving. This algorithm is one current approach to the management of acute diarrhea. <h3>Hospitalization vs Outpatient Management</h3> Whether the patient should be hospitalized or treated as an outpatient depends on a number of factors, including the nature of the underlying disease and the age of the patient as well as the degree of systemic toxicity, fever, and state of hydration. The following criteria usually should be followed in selecting those patients who should be admitted to the hospital: (1) the very young or elderly with severe diarrhea or (2) patients of any age with diarrhea and pronounced systemic toxemia, hyperpyrexia, or dehydration. While hospitalized, the patient's condition can be closely monitored and
Trimethoprim-sulfamethoxazole: another cause of recurrent meningitis
Authors: E. J. Haas
Journal: JAMA (1984)

<h3>To the Editor.—</h3> Recurrent meningitis usually suggests an incompletely healed fracture of the cribriform plate of the skull. It can also be seen with Behçet's disease, Mollaret's meningitis, familial Mediterranean fever, and with various immunodeficiencies such as complement deficiency, agammaglobulinemia, and asplenia.<sup>1</sup>We recently encountered another cause that might be of interest to practicing physicians. <h3>Report of a Case.—</h3> A 52-year-old woman was referred on May 13, 1983, for evaluation of recurrent meningitis. The results of analysis at the beginning of her previous attacks are listed in the Table. All cultures were sterile. The May 6, 1983, lumbarpuncture was done soon after the onset of symptoms; the attack itself was clinically indistinguishable from her other episodes. She was receiving cefotaxime sodium at the time of referral. The patient complained that severe sinus congestion had preceded many of her attacks of meningitis. She remembered taking Septra for symptoms of
Innocence Abroad
Authors: Sean Stitham
Journal: JAMA (1992)

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