tbuckley/cabot-search huggingface dataset:
STD clinics and the prevention of sexually transmitted diseases
Authors: Paul Cameron
Journal: JAMA (1986)

<h3>To the Editor.—</h3> Apparently speaking for the Centers for Disease Control (CDC), Dr Willard Cates<sup>1</sup>editorially scored moralistic criticisms of free sexually transmitted disease (STD) clinics. He ridiculed "moral solutions" to STD problems since "the history of public health" has demonstrated that moral approaches "actually hinder preventive health care," and, furthermore, that "controlling STDs in the future can best be accomplished through... continued public support of clinical services." The campaign of sophisticated vilification of traditional morality by Dr Cates and the CDC is without empirical merit. Our society has followed CDC sexual prescriptions for the past 40 years. Free STD clinics are now widespread, and we seldom "blame the victim" in accord with Dr Cates' guidelines. However, instead of serving "no useful purpose" (Dr Cates' interesting choice of words), historic morality helped keep STDs in check. Our recent nationwide random sexuality survey<sup>2</sup>found evidence that the fraction of
National Basketball Association Wives Take on Mammography Education
Journal: JNCI Journal of the National Cancer Institute (1992)

Journal Article National Basketball Association Wives Take on Mammography Education Get access JNCI: Journal of the National Cancer Institute, Volume 84, Issue 3, 5 February 1992, Page 147, https://doi.org/10.1093/jnci/84.3.147 Published: 05 February 1992
P04 * A RARE CASE OF PRIMARY CNS ANGIOSARCOMA PRESENTING AS AN INCOMPLETE GERSTMANN SYNDROME: A CASE REPORT AND REVIEW OF LITERATURE
Authors: K. J. L. Linay, M. C. F. Bernardo, E. Maranan
Journal: Neuro-Oncology (2014)

INTRODUCTION: Primary central nervous system angiosarcoma is a very rare malignancy, with only 22 cases reported in the literature for the past 26 years. A 60-year old Filipino woman, housewife, presented with 1 week history of difficulty performing daily mathematical equations, difficulty reading words, and difficulty writing. On neurologic exam, patient was found to be oriented to person, place, and time. There was note of dyscalculia, agraphia, and right-left disorientation. There were no finger agnosia, agraphesthesia, astereognosia, nor apraxia. Cranial MRI showed a 4 x 4 x 4.1 cm mass at the left parietal lobe. Total excision of the mass done and biopsy revealed angiosarcoma of the brain. Thorough search for another systemic lesion failed to show any other angiosarcomatous lesion. The patient refused any further radiotherapy or chemotherapy. METHOD & RESULTS: Soft tissue sarcomas comprise a small percent 1% of the malignant neoplasms, and of which only 0.5% comprise the primary brain OR spine sarcoma. In the review of literature that we did, of the 22 reported cases, the tumor was commonly located supratentorially (9/22), affecting middle to late ages with 3:1 male to female ratio. It is an aggressive tumor with a <2-year (range of survival is 4 months -3½ years) survival independent of the age, location, or whether chemotherapy or radiotherapy was given. As with the best of our knowledge, there has been no recorded case of angiosarcoma which presented with Gerstmann syndrome in the literature. CONCLUSION: We described the first reported case of primary CNS angiosarcoma in the Philippines and the 23rd worldwide. We also described the first case of angiosarcoma which presented with Gerstmann synd.
Medicine in Canada
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Polypoid Metastatic Hepatocellular Carcinoma of the Esophagus Occurring After Endoscopic Variceal Band Ligation
Authors: K. Kume, I. Murata, I. Yoshikawa, K. Kanagawa, M. Otsuki
Journal: Endoscopy (1999)

This report describes a rare case of metastatic hepatocellular carcinoma (HCC) presenting as a polypoid mass in the lower esophagus after endoscopic variceal band ligation (EVL). A 56-year-old man underwent EVL for variceal bleeding in September 1993. He presented with dysphagia and tarry stool in December 1993. An endoscopic examination revealed a semipedunculated polypoid mass at the lower part of the esophagus, where EVL had been performed 3 months previously. The histologic examination at autopsy revealed that the polypoid mass consisted of metastatic HCC that had spread via the retrograde portal flow.
Medizinisch-Chemisches Laboratoriums-Hilfsbuch.
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Die physikalische Therapie des praktischen Arztes. Herleitung allgemein gültiger Behandlungsregeln.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Terminal Life
Authors: Justine V. Cohen
Journal: JAMA Oncology (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Oncology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Oncology journal
The Cover
Authors: Bennard B. Perlman
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
EXHAUSTION PARALYSIS IN EPILEPSY.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Endocrine Aspects of Sarcoidosis
Authors: John L. Winnacker, Kenneth L. Becker, Sol Katz
Journal: New England Journal of Medicine (1968)

SOME of the endocrine aspects of sarcoidosis have been discussed in separate reports, but never in a comprehensive review. The purpose of this communication is to emphasize the diversity of clinical manifestations that may result from sarcoidosis of the endocrine and genital organs, and to review current concepts of the calcium metabolism in sarcoidosis. The pathogenesis of hypercalcemia and the problems encountered in its diagnosis and treatment are discussed in detail. The present review is based on a survey of the pertinent literature and on our own experience with endocrine disorders in patients with sarcoidosis.Hypercalcemia and Calcium MetabolismThe . . .
Effect of Neonatal Exposure to Estrogenic Compounds on Development of the Excurrent Ducts of the Rat Testis through Puberty to Adulthood
Authors: Jane S. Fisher, Katie J. Turner, Dennis Brown, Richard M. Sharpe
Journal: Environmental Health Perspectives (1999)

Neonatal exposure to diethylstilbestrol (DES) can alter the structure of the testicular excurrent ducts in rats. We characterized these changes according to dose and time posttreatment and established whether potent estrogens (ethinyl estradiol), environmental estrogens (genistein, octylphenol, bisphenol A, parabens), and tamoxifen induce such changes. Rats were administered these compounds neonatally and assessed at several time points during (day 10, or day 18 for some treatments) and after (days 18, 25, 35, and 75) the treatment period to detect any changes in testis weight, distension of the rete testis and efferent ducts, epithelial cell height in the efferent ducts, and immunoexpression of the water channel aquaporin-1 (AQP-1). Treatment with DES (10, 1, or 0.1 microg/injection; equivalent to 0.37, 0.037, or 0.0037 mg/kg/day, respectively) induced dose-dependent changes in testis weight and all parameters. These effects were most pronounced at days 18 and 25 and appeared to lessen with time, although some persisted into adulthood. Neonatal treatment with ethinyl estradiol (10 microg/injection; equivalent to 0.37 mg/kg/day) caused changes broadly similar to those induced by 10 mg DES. Administration of tamoxifen (2 mg/kg/day) caused changes at 18 days that were similar to those induced by 1 microg DES. Treatment with genistein (4 mg/kg/day), octylphenol (2 mg/injection; equivalent to 150 mg/kg/day), or bisphenol A (0.5 mg/injection; equivalent to 37 mg/kg/day) caused minor but significant (p<0.05) decreases in epithelial cell height of the efferent ducts at days 18 and/or 25. In animals that were followed through to 35 days and/or adulthood, these changes were no longer obvious; other parameters were either unaffected or were affected only marginally and transiently. Administration of parabens (2 mg/kg/day) had no detectable effect on any parameter at day 18. To establish whether these effects of estrogens were direct or indirect (i.e., resulting from reduced follicle-stimulating hormone/luteinizing hormone secretion), the above end points were assessed in animals in which gonadotropin secretion was suppressed neonatally by administration of a gonadotropin-releasing hormone antagonist. This treatment permanently reduced testis weight, but did not affect any of the other end points, apart from a minor transient reduction in efferent duct epithelial cell height at 18 days. This study suggests that structural and functional (expression of AQP-1) development of the excurrent ducts is susceptible to impairment by neonatal estrogen exposure, probably as a consequence of direct effects. The magnitude and duration of adverse changes induced by treatment with a range of estrogenic compounds was broadly comparable to their estrogenic potencies reported from in vitro assays.
Error in Affiliation
Authors: Katharine Harding, Emma Tallantyre, Neil Robertson
Journal: JAMA Neurology (2019)

those patients with the most active disease compared with treated cohorts in other western countries.However, alemtuzumab has been available in our center off-license since 2005, and our study's long-term outcomes 4 mirror those reported in another alemtuzumab-treated cohort. 5 The expansion in DMTs in the last decade has led to the development of several options to treat relapsing MS but a lack of data or consensus on DMT sequencing choices.We agree with the authors that RCT data are urgently needed 6 and, anticipating this, used the results from this observational study as preliminary data to inform the development of the Determining the Effectiveness of Early Intensive vs Escalation Approaches for the Treatment of Relapsing-Remitting Multiple Sclerosis (DELIVER-MS) trial.DELIVER-MS is a pragmatic parallel group, randomized clinical trial designed to compare outcomes of people treated with an early intensive approach vs an escalation approach.In 24 centers (12 in the United States and 12 in the United Kingdom), we aim to recruit 400 randomized and 400 observational patients with a definite diagnosis of MS, onset in the last 5 years, who are treatment naive, to receive either an escalation approach or an early intensive treatment approach.The primary end point is brain volume loss at 36 months and secondary end points include the accumulation of disability and health-related quality of life.We look forward to the results of this trial and hope that it will provide a more definitive answer to the question of the effect of initial treatment approaches on long-term outcomes in MS.
Replacement of operative blood loss of more than 1 liter with Hartmann's solution
Authors: B. Rigor
Journal: JAMA (1968)

A hundred patients each lost over 1,000 ml of blood while undergoing surgery and received two to three times that volume of Hartmann's solution. Postoperative mortality and morbidity were not affected by the lack of blood in the replacement regimen. Age group and physical condition of these patients were representative of the hospital population, and patients over 60 years old in American Society of Anesthesiologists (ASA) risk classifications 3 and 4 were included. Eighty-six percent of the group lost from 1 to 1.5 liters of blood; only 14% lost a larger amount. Serum electrolyte levels were unaffected. Hematocrit readings and total protein concentrations decreased but remained within physiologic limits. No unexpected complications were encountered in the postoperative period, and hospitalization was not prolonged. Only four patients required subsequent transfusions postoperatively.
Urologische Operationslehre.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 5125: A novel method for isolating high-quality UHMW DNA from 10 mg of freshly frozen or liquid-preserved animal and human tissue including solid tumors
Authors: Yang Zhang, James Broach
Journal: Cancer Research (2019)

Abstract High-quality UHMW DNA is key to success in optical mapping of long genomic DNA using Bionano Genomics Saphyr® system for de novo genome assembly and structural variation detection. Ideally, ~100 mg of tissue is frozen immediately upon collection using liquid nitrogen or dry ice, and stored at -80°C before DNA isolation. Practically, tissue amounts may be limited and collection often occurs at sites where low temperature preservation for storage and shipping may be unavailable. Here we present a novel method to isolate UHMW DNA from 10 mg of either freshly frozen or room temperature preserved animal and human tissue for subsequent enzymatic labeling using direct labeling and staining (DLS) to generate Bionano maps. With a TissueRuptor, 10 mg tissue is homogenized followed by a three-step purification process before embedding the purified nuclei in agarose gel plugs. This process takes less than 3 hours for a batch of 6 samples. Using this method, we have successfully isolated high quality UHMW DNA from various tissue types of rat and human including solid tumors. The method is very attractive compared to other protocols because: 1) tissue preservation, shipping and handling can be done at room temperature, 2) uses very small amount of tissue - possible application for rare samples and human tissue biopsy tests, and 3) the length and quality of the resulting single molecules generate high quality optical maps for genome finishing and SV calling. Citation Format: Yang Zhang, James Broach. A novel method for isolating high-quality UHMW DNA from 10 mg of freshly frozen or liquid-preserved animal and human tissue including solid tumors [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 5125.
Developmental Med &amp;amp; Child Neurology, London
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal