tbuckley/cabot-search huggingface dataset:
"THE PHYSIOLOGIC AND THERAPEUTIC ACTION OF LIGHT"
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Strabismus
Authors: Sumner D. Liebman
Journal: New England Journal of Medicine (1964)

STRABISMUS is an extremely important ophthalmologic problem since it affects about 5 per cent of the population. If a person is unable to direct the line of vision of both eyes simultaneously to a given point, one eye must be deviating, and that person has strabismus. Strabismus implies an improper relation of one eye to the other. The proximity of the cornea to the inner or outer canthus is not diagnostic and may be deceiving. Thus, many children with pronounced epicanthic folds are often wrongly diagnosed as having strabismus when, in fact, they are quite capable of single binocular vision. . . .
Neurology
Authors: Maurice Van Allen
Journal: JAMA (1979)

<h3>Stroke: Its Prevention, Its Treatment</h3> Stroke, risk factors for degenerative vascular disease, and transient ischemic attacks (TIAs) continue to be major preoccupations of those in neurology. The majority of TIAs seem to be due to forward embolism from atheromatous plaques in the major vessels. Endarterectomy, anticoagulant agents, and platelet antiaggregating drugs (aspirin, sulfinpyrazone, dipyridamole) are the available modalities for treatment after cardiac and hematologic disorders have been eliminated as causes for circulatory insufficiency. Millikan and McDowell<sup>1</sup>have provided an excellent review of the subject. When angiography demonstrates an atheromatous plaque at the carotid bifurcation, many investigators prefer surgical treatment. Still, however, the risks of both angiography and surgery must be weighed, and we have as yet no consensus on the long-term advantages of surgical operation over medical treatment.<sup>2,3</sup>The frequency of TIAs can be reduced if anticoagulants such as heparin sodium and warfarin sodium are used early on,
Early Greek State Physicians
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tumors of the Breast.
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phase II study of docetaxel (DTX) and S-1 as neoadjuvant chemotherapy for potentially R0 advanced gastric cancer.
Authors: M. Watanabe, Y. Emi, Y. Kakeji, E. Oki, Y. Sakaguchi, K. Yoshida, N. Hirabayashi, T. Yamanaka, H. Baba, Y. Maehara
Journal: Journal of Clinical Oncology (2011)

106 Background: This trial sought to evaluate the efficacy and safety of preoperative chemotherapy with DTX plus S-1 for advanced gastric cancer with poor prognosis even after R0 curative resection. Methods: Preoperative staging was confirmed by laparoscopy. Eligibility criteria included 1) negative peritoneal cytology, H0, P0 and M0, 2) possible curative resection, and 3) ECOG PS 0-1. Patients received DTX (35 mg/m 2 ) on days 1 and 15, and daily oral administration of S-1 (80 mg/m 2 /day) for days 1–14 every 4 weeks of 2 courses, followed by gastrectomy with D2 lymphadenectomy. The primary endpoint was pathological response rate (pRR), which was defined as degeneration occupying more than one-third of the cross-sectional surface area of the tumor. A sample size of 45 was planned for the expected pRR of 40% and threshold value of 20%, with one-sided alpha of 0.05 and beta of approximately 0.1. This study was registered in the UMIN clinical trial registry (UMIN000000875). Results: A total of 47 patients were centrally registered between November 2007 and November 2009 from 14 centers. All patients were eligible for analysis. The median age was 63 (range 37–79); male/female: 36/11; PS0/1:41/6; and clinical stage IIIA/IIIB: 31/16. The target pRR was 47% (90% CI, 34–60%; p &lt; 0.0001). Forty six patients (98%) underwent surgery, in whom curative resection was performed in 44 patients, and 37 patients completed the protocol treatment. The response to preoperative chemotherapy was PR/SD/PD/NE in 16/24/2/5 with a response rate of 34%. The most common toxicities of neoadjuvant chemotherapy were grade 3/4 neutropenia (42%), febrile neutropenia (4%), grade 2 anorexia (21%), and fatigue (15%). Seven did not complete the neoadjuvant therapy due to 2 allergic reaction, 1 grade 3 anorexia, 2 grade 2 nausea and anorexia, 2 PD (all 7 had gastrectomy). Major operative morbidity included pancreatic fistula (9%), abdominal abscess (11%), pneumonia (2%), and anastomotic leakage (0%). No patients died due to surgical complications. Conclusions: The combination of DTX and S-1 was well tolerated and promising as a preoperative chemotherapy regimen for patients with potentially resectable advanced gastric cancer. [Table: see text]
Renal allotransplantation for bilateral renal tumors
Authors: P. R. Jochimsen
Journal: JAMA (1969)

A patient with tuberous sclerosis and renal failure secondary to bilateral multiple hamartomas and clear-cell tumors of the kidneys had renal allotransplantation performed. A second patient with the same syndrome has undergone nephrectomy for hamartomas of the right kidney and has a large tumor mass in the remaining kidney. This patient will have a renal transplant when her status requires. In spite of a systemic disorder, we consider these patients good candidates to have transplants. Clearcell renal cancers in patients with tuberous sclerosis do not appear to behave as malignancies and do not offer a contraindication to transplantation. Children with bilateral Wilm's tumors and individuals with bilateral clear-cell tumors of both kidneys or of a sole functioning kidney may also greatly benefit from having a renal transplant.
Corrigendum to “Delivery of oncolytic adenovirus into the nucleus of tumorigenic cells by tumor microparticles for virotherapy” [Biomaterials 89C (2016) 56–66]
Authors: Li Ran, Xiaohua Tan, Yanchun Li, Huafeng Zhang, Ruihua Ma, Tiantian Ji, Wenqian Dong, Tong Tong, Yuying Liu, Degao Chen, Xiaonan Yin, Xiaoyu Liang, Ke Tang, Jingwei Ma, Yi Zhang, Xuetao Cao, Zhuowei Hu, Xiaofeng Qin, Bo Huang
Journal: Biomaterials (2020)
Chest pain in patients with normal coronary arteriograms
Journal: BMJ (1984)

In rheumatoid arthritis the bone scan may antedate clinical and radiological manifestations of inflammatory synovitis.33Once a diagnosis has been established, however, a bone scan will not provide any additional information and therefore its role in the routine management of patients with rheumatoid arthritis is limited.21It has been suggested that the bone scan may prove to be an accurate means of monitoring a patient's response to treatment, but any advantage in clinical practice over simpler techniques remains to be established.Acute sacroiliitis, such as occurs in ankylosing spondylitis, will produce a positive bone scan image, and the bone scan may detect radiologically negative sacroiliitis.2'The dif- ficulty in assessing the sacroiliac joints in the bone scan is that they normally appear hotter than the surrounding pelvis and sacrum, and even more so in young patients, in whom sacroiliitis is most frequently seen.Furthermore, while sacroiliitis may be unilateral, it is often bilateral and the abnormality may be difficult to detect on subjective evaluation of a bone scan image.To overcome such difficulties a quantitative technique, using a computer, has been used to relate tracer uptake by each sacroiliac joint to that in the sacrum.4This ratio is abnormally high early in the disease when x ray findings are often minimal or absent but tends to
Postchemotherapy Ejaculatory Azoospermia: Fatherhood With Sperm From Testis Tissue With Intracytoplasmic Sperm Injection
Authors: M. N. Damani
Journal: Journal of Clinical Oncology (2002)

PURPOSE: To define the success of testis sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI) in azoospermic men with a history of chemotherapy. PATIENTS AND METHODS: In a retrospective study, 23 men with ejaculatory azoospermia and a history of chemotherapy underwent TESE in a search for usable spermatozoa. In six patients cryopreserved tissue and in nine patients fresh tissue provided sperm for an ICSI cycle. Histologic analysis of the testis was performed in all patients. The presence or absence of sperm, fertilization rates with ICSI, and final outcomes of pregnancy were recorded. RESULTS: Spermatozoa were found on TESE in 15 (65.2%) of 23 men. On histopathology, the predominant pattern observed was Sertoli cell only (47.8%), followed by hypospermatogenesis (30.4%), mixed (17.4%), and late maturation arrest (4.3%). The fertilization rate was 65.2%, and ongoing/delivered pregnancies occurred in 30.8% of cycles. Six healthy boys and four healthy girls have been born to date. CONCLUSION: Men who are azoospermic and have had prior cytotoxic therapy make up a small subgroup of males with nonobstructive azoospermia. It is important to define and characterize this subgroup and better define their true fertility potential. Approximately two thirds of these men have retrievable testis sperm, which may be used with ICSI to have healthy offspring. This exciting avenue for paternity has heretofore not been available to such patients.
PD-L1 in tumor microenvironment mediates resistance to oncolytic immunotherapy
Authors: Dmitriy Zamarin, Jacob M. Ricca, Svetlana Sadekova, Anton Oseledchyk, Ying Yu, Wendy M. Blumenschein, Jerelyn Wong, Mathieu Gigoux, Taha Merghoub, Jedd D. Wolchok
Journal: Journal of Clinical Investigation (2018)
Predicting hemodynamic data and presence of scar tissue from electromechanical mapping: Correlation with cardiac magnetic resonance imaging Emerson C. Perin, Guilherme Silva, Rogerio Sarmento-Leite, Marcus Howell, Raja Muthopillai, Brenda Lambert, Scott Flamm. Texas Heart Institute, Houston
Journal: Journal of the American College of Cardiology (2001)
Weatherman, MD
Authors: G.G. Liddle
Journal: JAMA (1972)

<h3>To the Editor.—</h3> As I sit behind my typewriter throne, I gaze out on a blizzard, a genuine blizzard, with sleet, snow, and wind of gale propertion. Our regional weatherman's 7 AM prophecy was that there was a 10% chance of snow today, and that the chill factor was 32 F. During the day, the temperature has dropped 12 F, 5 inches of hardpacked snow cover the ground; it's three o'clock in the afternoon, and things look pretty grim. But I can't sue the weatherman. Obviously, physicians should use his devices to avoid malpractice suits and public criticism that physicians know least about what medical services the people need. <h3>Counsel for the Plaintiff</h3> You told the patient he had heart disease and needed surgery! Don't deny it! <h3>Liddle:</h3> To the contrary. I told the patient there was a 26% chance he had heart disease, and a 10% chance that if
Einführung in das Studium der Nervenkrankheiten für Studierende und Aerzte.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Essentials of Pharmacology and Materia Medica for Nurses
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Editorial: Child development study.
Journal: BMJ (1974)

of this lesion is accentuated if the patient slides down and forward under the seat belt so that the full force of the belt is transmitted to the abdominal wall and the subjacent viscera because the belt is no longer anchored by the pelvis.This process, which they term "submarining," is more likely to occur if the patient is sitting in a soft seat or if the belt is applied loosely.J. Sube and his colleagues6 record a deceleration type of accident in which the mesocolon and outer layers of the sigmoid colon were torn away, only an intact mucosal tube being left.They conclude that the mechanism in such a case is that the inertia of the fluid-filled bowel is suddenly halted by the limits of its mesocolon.Recently J. Shennan7 has recorded two patients with iso- lated injury to the left colon produced by the lap strap of the seat belt.Both wore seat belts comprising lap strap and diagonal belt, both were the drivers, and both were involved in head-on collisions.These patients were able to walk away from the accident, apparently without serious harm.The first, who sustained ischaemic damage to the descending colon with a segment of gangrene, developed pain after 12 hours and had exteriorization of the damaged segment of colon performed at operation nearly 24 hours after injury.The second patient developed severe pain three hours after the accident and at laparotomy was found to have an almost completely severed descending colon.Again exteriorization was performed.Shen- nan points out that most reports ofthe "seat belt syndrome" in which either the large or small intestine is injured have stressed that delay before the patient presents himself is common.There is no doubt that delayed rupture of the bowel after traumatic ischaemia does occur.Though the rupture usually appears before the fourth day, it may be delayed for longer periods.As car seat belts come into more general use the possibility of visceral injury should be borne in mind.In particular, care- ful and continued observation, if necessary for several days, is needed to exclude ischaemic damage and delayed rupture of the intestine.
Peripheral radionuclide angiography
Authors: P. Matin
Journal: JAMA (1979)

RADIOISOTOPES have been used for the dynamic visualization of blood flow through vessels and organs since the invention of the scintillation camera in the early 1960s. Known as radionuclide angiography, scintiangiography, and nuclear flow studies, the technique is simple, safe, and relatively inexpensive. However, until recently, it was able to provide only general information about the blood flow to the extremities. Recent improvements in nuclear medicine instrumentation and techniques have permitted major improvements in the ability of radionuclide angiography to image and quantitate peripheral arterial blood flow. This article describes the technique and discusses its use in studying abnormalities such as stenosis and aneurysm of the vessels of the extremities. Because it is noninvasive and relatively inexpensive, radionuclide angioography is ideal for examination of patients both preoperatively and postoperatively. The fact that relative quantitation of blood flow is possible makes serial studies more objective and accurate. The accuracy of radionuclide
Ice Chewing
Authors: C. E. Schorer
Journal: JAMA (1971)

<h3>To the Editor.—</h3> An EDITORIAL inThe Journal(<b>207</b>:552, 1969) regarding ice chewing as a symptom of pernicious anemia brought to mind that ice is useful for patients treated with antidepressants such as imipramine. One of the commonest side effects of the tricyclic antidepressants is dry mouth. Two of my patients taking these medications have told me that a craving and increased use of ice chips have occurred, and that ice is more effective and longer acting than cold water without the loading effect, and more gratifying than mints or chewing gum. This observation also brings to mind a recent report that water-deprived animals will prefer ice to water, suggesting a different and more immediate drive satisfaction in the case of hyperosmolarity (and presumably dry mouth).<sup>1</sup>At any rate, some physicians may be glad to learn how to palliate this almost inevitable side effect of the antidepressants.
FROM INTERNAL COMBUSTION TO ELECTRICITY
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Improved survival rates among testis cancer patients in the United States
Authors: F. P. Li
Journal: JAMA (1982)

Mortality rates of testis cancer among US whites declined 34% between 1973 and 1978. The change is attributable to improved therapy for patients with disseminated testis cancer other than seminoma. Thirty-month survival rates among these patients increased from 22% in 1973 to 1976 to 56% in 1977 to 1979 in nine geographic areas monitored by the Surveillance, Epidemiology, and End Results Program of the National Cancer Institute. (<i>JAMA</i>1982;247:825-826)