tbuckley/cabot-search huggingface dataset:
HEALTH AND HIGHER EDUCATION.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Recommended Childhood and Adolescent Immunization Schedule—United States, January–June 2004
Journal: JAMA (2004)

S ADVISORY COMMITtee on Immunization Practices (ACIP) reviews the recommended childhood and adolescent immunization schedule to ensure that it is current with changes in manufacturers' vaccine formulations and reflects revised recommendations for the use of licensed vaccines, including those newly licensed.The recommended childhood and adolescent immunization schedule for January-June 2004 (Figure ), recommendations, and format have been approved by ACIP, the American Academy of Family Physicians, and the American Academy of Pediatrics. Catch-Up Childhood and Adolescent Immunization Schedule
Clinical Journal of Sport Medicine
Authors: William P. Hamilton
Journal: JAMA (1992)

Sponsored by the Canadian Academy of Sport Medicine, "the<i>Clinical Journal of Sport Medicine</i>is an international, refereed journal published for clinicians with a primary interest in sports medicine practice." The journal includes articles in "(1) diagnosis, treatment, and rehabilitation of sport- and exercise-related injuries; (2) medical illnesses induced by or exacerbated by exercise; (3) relationship between exercise and health, and the exercise prescription; and (4) the medical care of physically active individuals." While there are similarities with the<i>American Journal of Sports Medicine</i>, the<i>Clinical Journal of Sport Medicine</i>contains features that make it uniquely useful. As the title implies, articles are primarily of a clinical nature and appropriate for professionals in any discipline. Typically, they are short and easily read. Some of the articles, such as that on dealing with the asthmatic athlete, will have a practical use for team physicians and orthopedists alike. The journal has published
Mutagenic and Carcinogenic Properties of Polycyclic Aromatic Hydrocarbons
Authors: Yu. V. Pashin, L. M. Bakhitova
Journal: Environmental Health Perspectives (1979)

The rapid development of the chemical industry, combustion of fossil fuels, and smoking of tobacco have resulted in contact of the general population with benzo(a)pyrene and other carcinogenic aromatic hydrocarbons. Persons especially at risk occupationally are those engaged in thermal processing of oil shale, coal, and heavy residual petroleum. It has been shown that polycyclic aromatic hydrocarbons require metabolic activation before they can act as mutagens or carcinogens. This metabolic activation results from interaction with microsomal enzymes present in many body cells, yielding reactive epoxides which react with DNA and produce mutations in the count frame shift or participate in covalent bounding. While opinions differ regarding the relative role of these processes in mutagenesis, considerable evidence exists which links mutagenesis and carcinogenesis. Metabolites of the polycyclic aromatic hydrocarbons which are carcinogenic are usually mutagenic, which supports the hypothesis that damage to chromosomes plays an important role in carcinogenesis. These facts open the possibility to monitoring the spread of carcinogenic substances in the biosphere by relatively simple tests whose endpoint is mutagenesis.
Correction: Camplylobacter colitis
Journal: BMJ (1979)

abdomen was closed.A mesenteric biopsy specimen contained fibroblastic and collagenous connective tissue.Postoperatively the patient's symptoms slowly regressed, and after one week he was able to take solids.The haemoglobin concentration was 12-6 g/dl, erythrocyte sedimentation rate 33 mm in the first hour (Westergren), and blood urea concentration 4-9 mmol/I (29-5 mg/100 ml).Tests were positive for antinuclear factor (1/1000) and rheumatoid factors (sheep cell agglutination test 1/1256; latex test 1/640).Chest radiography showed bilateral lower zone reticular shadowing consistent with pulmonary fibrosis.Results of barium studies several months after laparotomy were compatible with PSS.1 Barium meal and follow-though examination showed a widened, atonic oesophagus 7 cm diameter at its lower end.The duodenal loop and proximal two-thirds of the small bowel were severely dilated, and transit was delayed.Barium enema disclosed a voluminous rectum and sigmoid colon, which were atonic and smooth in outline.Reduced xylose excretion (3-2 g 45 min after a 25 g load) and increased three-day faecal fat excretion (128 mmol; 36-4 g) were also compatible with gastrointestinal PSS.The patient was treated with penicillamine and tetracycline and showed modest improvement.
The Essentials of Pathology
Journal: JAMA (1883)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Computer Fair
Authors: HAROLD M. SCHOOLMAN
Journal: Annals of Internal Medicine (1984)

Editorials1 January 1984Computer FairHAROLD M. SCHOOLMAN, M.D., EDWARD H. SHORTLIFFE, M.D., PH.D.HAROLD M. SCHOOLMAN, M.D.Search for more papers by this author, EDWARD H. SHORTLIFFE, M.D., PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-100-1-148_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe American College of Physicians, recognizing the increasing role that computer-assisted data management is playing in office operations, patient care, and continuing education, initiated at its last annual session a workshop on "computer literacy." At the 1984 Annual Session (26-29 April in Atlanta) the College is planning a "computer fair" in which major hardware, software, and information vendors will exhibit their products. The fair will also offer attendees an opportunity to experiment with the programs and equipment being shown. In addition, eight sessions are planned on various aspects of the use of computers in medicine (beginning and intermediate computer literacy... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Telecommunications Subcommittee American College of Physicians PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 January 1984Volume 100, Issue 1Page: 148-148KeywordsComputer softwareComputersData managementLiteracyPatients Issue Published: 1 January 1984 PDF downloadLoading ...
Impact of Closure of a Sexually Transmitted Disease Clinic on Public Health Surveillance of Sexually Transmitted Diseases--Washington, D.C., 1995
Journal: JAMA (1999)

In April 1995, a public sexually transmitted disease (STD) clinic in the northwest (NW) ward of the District of Columbia closed, leaving one public STD clinic in the southeast (SE) ward to provide public STD services for the entire city. This report summarizes an investigation by CDC following a request from the District of Columbia Department of Health's STD program to evaluate the impact of the NW STD clinic closure on STD case reports. The findings of this investigation indicate that the clinic closure resulted in a marked decrease in reported syphilis in the NW ward, and suggest that NW ward residents with syphilis and their partners may not have received proper diagnostic testing, therapy, and counseling.
Pacemaker Mania
Authors: John A. Kastor
Journal: New England Journal of Medicine (1988)

All doctors can be divided into three groups: those who never think about pacemakers, those who always think about pacemakers, and the rest, who think about pacemakers for the right patients at the right time. The first group occasionally undertreats the patient with lightheadedness or syncope and a bradyarrhythmia; the second group may overtreat such a patient; but most physicians apply the principles of pacemaker treatment properly and thoughtfully.It is to the customs of one variety of the second group, the overzealous Philadelphia "pacerologist," that Greenspan and his colleagues have directed our attention in this issue of the Journal . . .
&lt;TITLE&gt;Depression&lt;/TITLE&gt;
Authors: Mi Hwang, Richard Glass, Jeff Molter
Journal: JAMA (1998)

BLUESin physical performance was most pronounced in older adults with severe depressed mood, but similar effects were also found among the less severely depressed elderly people.The researchers believe the findings of this and other studies suggest that depression and poor physical function are mutually reinforcing and cause a downward spiral in the physical and psychological health of older people.They suggest that prevention or reduction of depressed mood could play a role in reducing functional decline in the elderly.A diagnosis of major depression is made when at least 5 of the typical symptoms persist for at least 2 weeks.However, having even a few of these symptoms can cause suffering and impairment.Anyone who experiences persisting symptoms of depression should be evaluated by a physician.Fortunately, several forms of treatment have been shown to be effective for depression.
Wilhelm C. Hueper, M.D.: A tribute
Journal: JNCI Journal of the National Cancer Institute (1979)

Journal Article Wilhelm C. Hueper, M.D.: A tribute Get access JNCI: Journal of the National Cancer Institute, Volume 62, Issue 4, April 1979, Page 713, https://doi.org/10.1093/jnci/62.4.713 Published: 01 April 1979
Investigations of AIDS patients with no previously identified risk factors
Authors: K. G. Castro
Journal: JAMA (1988)

Through Sept 30,1987, two thousand fifty-nine patients with acquired immunodeficiency syndrome (AIDS) and no recognized risk factors were reported to the Centers for Disease Control. Risk history was incomplete or unobtainable for 921 (45%) of them. Risk factors were ultimately identified for 825 (72%) of the remaining 1138. Another 32 persons (3%) did not meet the case definition for AIDS. Risk factors could not be identified for the remaining 281 patients (25%), despite additional information. Of these, 178 (63%) were interviewed with standard questionnaires; 38% reported sexually transmitted diseases and 34% of the men reported sexual contact with prostitutes. There was no evidence for new transmission modes. Although the proportion of AIDS patients with undetermined risk factors has increased significantly during the past year, the adjusted proportion shows no significant change over time. Thus, follow-up of AIDS patients with no apparent risk factors suggests that modes of transmission for human immunodeficiency virus have remained stable. (<i>JAMA</i>1988;259:1338-1342)
PEPI in Perspective
Authors: Bernadine Healy
Journal: JAMA (1995)

Estrogen is good for a woman's heart. While generally accepted when the estrogen is produced naturally, this theory has been a matter of great controversy when the estrogen is administered "artificially" in hormone replacement therapy (HRT) for women during and after menopause. After a half century of conflicting data, we can affirm with growing confidence that, at the very least, estrogen reduces key cardiovascular risk factors in women at a time when they become especially vulnerable to heart disease, namely, after 50 years of age. See also p 199. In this issue ofThe Journal, the Postmenopausal Estrogen/Progestin Interventions (PEPI) investigators report on one aspect of the many findings that we can expect to learn over the next few years from their important National Institutes of Health (NIH)-supported multicenter efforts.<sup>1</sup>Their report focuses on the effect of HRT, given in four different formulations, compared with short-term use of placebo
Peripheral Vascular Diseases
Authors: Charles V. Menendez, Robert R. Linton
Journal: New England Journal of Medicine (1954)

SINCE 1949, when the last progress report was published,32 important advances have been made in the surgical treatment of peripheral vascular diseases, especially in the replacement of injured and diseased arteries by some type of blood-vessel graft. This does not mean that sympathetic neurectomy and other methods in use for many years have been supplanted, but that the restoration of continuity of a major artery with vascular grafts is a supplement to the older and more established procedures.Diseases of ArteriesPeripheral ArteriosclerosisThe problem of arteriosclerosis is an ever-growing one because of the increasing longevity of the general population. . . .
Snoring.
Authors: J Rees
Journal: BMJ (1991)

Institute for Fiscal Studies estimates that this will result in a 46% increase in the volume of alcohol drunk in each household.4As a participant in the WHO Health for All by the Year 2000 project Britain is also committed to make "significant decreases in health damaging behaviour such as the use of alcohol."At the moment these two commitments seem irreconcilable.What is needed is an energetic political campaign on alcohol problems.At the centre should be an organisation equivalent to ASH, which has campaigned so successfully against smoking.It will need active support from organisations like the BMA and other professional associations.The ministerial committee should be resuscitated and given objectives and teeth.If the government is serious about setting targets to improve the nation's health its forthcoming green paper should include plans to reduce alcohol consumption.A united front is needed.Half hearted attempts at tackling the problem of alcohol abuse will get nowhere.
Editor's audit report for 1999
Journal: British Journal of Sports Medicine (2000)

Warm upWhere we are, how we do it, where we are going, and what others do.This issue sets out to create a benchmark in education.With many important recent developments in sports medicine education in the UK, we invited experts to address some of the current issues, look at methods of delivery, and give a vision of the future.To put these developments in context we present snapshots from Finland, Canada, Germany, and Australia (pages 235-244).The final stage of our educational odyssey is a survey of teaching in undergraduate medical schools (page 244) and a short paper describing the qualities required in a sports medicine specialist (page 243).Elsewhere in this issue, we look at common sporting topics from unusual angles.Running and relaxation seem to fit well together but research into runners who practise relaxation techniques is unexpected (page 268).Osteoporosis and oestrogen are often linked but examining bone mineral density and testosterone in male runners is a new
PARATYPHOID CARRIED IN HEAD CHEESE
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Leads from the MMWR. Human rabies--Texas
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Questions and Answers
Journal: JAMA (1980)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Molecular Conformation, Receptor Binding, and Hormone Action of Natural and Synthetic Estrogens and Antiestrogens
Authors: W. L. Duax, J. F. Griffin, C. M. Weeks, K. S. Korach
Journal: Environmental Health Perspectives (1985)

The X-ray crystallographic structural determinations of synthetic estrogens and antiestrogens provide reliable information on the global minimum energy conformation of these molecules or a local minimum energy conformation that is within 1 or 2 kcal/mole of the global minimum. In favorable cases, state-of-the-art molecular mechanics calculations provide quantitative agreement with X-ray results and information on the relative energy of other local minimum energy conformations not observed crystallographically. Because the conformation of diethylstilbestrol (DES) observed in solvated crystals has an overall conformation and dipole moment more similar to estradiol it is the form more likely to bind to the receptor and produce hormone activity. Either phenol ring of DES can successfully mimic the estradiol A-ring in binding to the receptor. Indenestrol A (INDA) and indenestrol B (INDB) have nearly identical fully extended planar conformations. Either the alpha or gamma rings of these compounds may mimic the A ring of estradiol and compete for the estrogen receptor. Although there are eight distinct ways in which molecules of a racemic mixture of INDA or INDB can bind to the receptor, not all of them may be able to elicit a hormonal response. This may account for the reduced biological activity of the compounds despite their successful competition for receptor binding. The minimum energy conformations of Z-pseudodiethylstilbestrol (ZPD) and E-pseudodiethylstilbestrol (EPD) are bent in a fashion similar to that of indanestrol (INDC). These molecules have good binding affinity suggesting that the receptor does not require a flat molecule. Therefore these conformations would appear to be compatible with receptor binding, but only the Z isomer has an energetically allowed extended conformation that accounts for its observed biological activity relative to DES.
Technology for Automated Analysis of Maize Pollen Used as a Marker for Mutation: 1. Flow-Through Systems
Authors: Harry W. Tyrer
Journal: Environmental Health Perspectives (1981)

Maize pollen is used as a monitor for environmental pollutants. Mutant pollen grains (induced by environmental pollutants) are detectable above a background frequency of 5 or less in 10(5). To enumerate a satisfactory number of mutant grains, it is necessary to count 10(6) grains in a sample, a laborious, time-consuming process which should be amenable to automated analysis techniques. High resolution image analysis technology has been used in the morphologic assessment of rare cells in a sample, provided a suitable training set could be devised to instruct the computer on the characteristics of the rare cells. On the other hand, flow cytometry uses primarily cytochemical means for detection and has been shown to detect rare events. Hence, the two technologies, which may be viewed as complementary, are suitable for the task. Alternatively, a hybrid technology employing both cell sorter and image analysis techniques may be extremely desirable for this problem. The potential for archival storage of analyzed samples is very attractive when considering the possibility of an adversary relationship between a putative regulator and polluter.