tbuckley/cabot-search huggingface dataset:
Errors in Drug Dosages.
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diabetes can be managed as well in primary care as in hospital
Journal: BMJ (1998)

Changed criteria for diabetes need further researchIn 1997 the American Diabetes Association changed the diagnostic fasting plasma value for glucose from 7.8 to 7.0 mmol/l.For screening and epidemiological studies they no longer recommended the standard 75 g oral glucose tolerance test recommended by the WHO.The DECODE Study Group's reanalysis of epidemiological studies in eight European countries-more than 26 000 patients-found that the two diagnostic criteria agreed in only 431 of 1517 people classified as diabetic (p 371).Because of this reclassification the group says that the WHO should wait for results of further reanalyses, with focus on prognostic impact, before it considers adopting the ADA criteria.
Back down the Ridge.
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Epithelial Na+ Channel: Cell Surface Insertion and Retrieval in Na+ Homeostasis and Hypertension
Authors: P. M. Snyder
Journal: Endocrine Reviews (2002)

The epithelial Na+ channel (ENaC) forms the pathway for Na+ absorption in the kidney collecting duct and other epithelia. Dominant gain-of-function mutations cause Liddle's syndrome, an inherited form of hypertension resulting from excessive renal Na+ absorption. Conversely, loss-of-function mutations cause pseudohypoaldosteronism type I, a disorder of salt wasting and hypotension. Thus, ENaC has a critical role in the maintenance of Na+ homeostasis and blood pressure control. Altered Na+ absorption in the lung may also contribute to the pathogenesis of cystic fibrosis. Epithelial Na+ absorption is regulated in large part by mechanisms that control the expression of ENaC at the cell surface. Nedd4, a ubiquitin protein ligase, binds to ENaC and targets the channel for endocytosis and degradation. Liddle's syndrome mutations disrupt the interaction between ENaC and Nedd4, resulting in an increase in the number of ENaC channels at the cell surface. Aldosterone and vasopressin also regulate Na+ absorption to defend against hypotension and hypovolemia. Both hormones increase the expression of ENaC at the cell surface. The goal of this review is to summarize recent data on the regulation of ENaC expression at the cell surface.
Ineffectiveness of isoxsuprine on intermittent claudication
Authors: D. E. Strandness
Journal: JAMA (1970)

The usefulness of isoxsuprine hyldochloride for the treatment of intermittent claudication was studied in 20 patients with arteriosclerosis obliterans. The study consisted of two four-week periods during which the patient was treated with both drug and placebo, the order of which was randomly assigned. The pattern of the postexercise hyperemic response was measured by the ankle systolic blood pressure response to exercise. A comparison of the drug and placebo treatment periods indicated that isoxsuprine did not improve the hyperemic response to exercise. On the basis of these data, it was not possible to demonstrate that isoxsuprine was useful in the treatment of intermittent claudication.
Highlights
Journal: JAMA Dermatology (2016)

Polycystic Ovary Syndrome Cutaneous and Systemic Associations 391Polycystic ovary syndrome (PCOS) aff ects 2% to 7% of women, and many of these women experience some of the classic cutaneous fi ndings of acne, hirsutism, and androgenic alopecia.In this retrospective cross-sectional study, Schmidt et al demonstrate that, although acne is common in women with PCOS, it did not distinguish between women suspected of having PCOS and those meeting the diagnostic criteria.Hirsutism and acanthosis nigricans were the most useful cutaneous indicators to distinguish those most at risk among a suspected PCOS population.
Contents: (Adv. Healthcare Mater. 15/2015)
Journal: Advanced Healthcare Materials (2015)

Effi cient penetration and uniform distribution of nanoparticles inside solid tissues and tumors is paramount to their therapeutic and diagnostic success.Here we report that disk-like, low aspect-ratio poly(ethylene glycol)-based anionic nanocylinders, as compared to corresponding high-aspect ratio nanorods, are more effi cient carriers for biomolecule delivery inside spheroids, a model representing the intervascular region of solid, tumor-like tissues.
Arterial Hypertension and Irradiation Damage to the Nervous System
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Genetic and Environmental Contributions to Childhood Growth in Stature and Lifetime Overweight Risk.
Authors: Stefan A Czerwinski, Jeff T Williams, Wayne Wisemandle, Bradford Towne, Ellen W Demerath, Shumei S Guo, Wm. Cameron Chumlea, Roger M Siervogel
Journal: Circulation (2001)

P09 The prevalence of childhood overweight and obesity in the US continues to increase. Epidemiological studies have shown that children who mature earlier tend to have an increased risk of being overweight in adulthood. Acknowledging that measures of overweight and patterns of human growth are under moderate to strong genetic control, we examined the nature of these associations using a bivariate variance components approach to estimate the genetic and environmental correlations between lifetime overweight status and parameters of the adolescent growth spurt. Serial stature data from 490 participants in the Fels Longitudinal Study were used to derive three adolescent growth curve parameters: peak height velocity (PHV), age at PHV, and height at PHV. Three categories of lifetime overweight status were determined from over 16,000 serial observations according to age at onset of overweight: early-onset overweight (BMI &gt;25 kg/m 2 before age 25 y), late-onset overweight (BMI &gt;25 kg/m 2 after age 25 y), and never overweight (never having a BMI measurement &gt;25 kg/m 2 ). Those classified as overweight also needed to meet certain criteria (i.e., maintenance of BMI &gt;25 kg/m 2 in 80% of all subsequent visits following the first presentation). Heritability estimates (h 2 ) for the adolescent growth parameters are h 2 =0.54 for PHV, h 2 =0.74 for age at PHV, and h 2 =0.92 for height at PHV. Heritability estimates for lifetime overweight status range from 0.52-0.57 depending upon the age at onset categorization. Although all of the traits examined are highly heritable, preliminary analyses reveal little effect of shared genes between the adolescent growth curve parameters and the lifetime overweight status categories; the genetic correlations are low and insignificant. There is, however, a statistically significant negative environmental correlation (ρ e =-0.40) between age at PHV and the lifetime overweight status category contrasting never overweight with early/late overweight. These results suggest that environmental influences on the timing of the adolescent growth spurt may be more influential in predicting adult risk of overweight than shared genetic factors.
A Report on the Biliary Secretions of the Dog: with Reference to the Action of Cholagogues
Authors: W. Rutherford
Journal: BMJ (1879)

Benzoic acid is said to act as a stimulant of the system generally, and particularly of the kidneys, mucous membrane of the bladder, and bronchial glands.It is nowhere stated to be a cholagogue.Yet it is sometimes ved 'empirically in hepatic affections.-Tanner, in his Prac-
Left ventricular pseudoaneurysm. Its recognition and significance
Authors: A. H. Dachman
Journal: JAMA (1981)

CARDIAC rupture is a major cause of mortality after myocardial infarction.<sup>1,2</sup>In a small percentage of patients, cardiac rupture is not a catastrophic event, but, rather, results in the formation of a pseudoaneurysm. Pseudoaneurysm is the result of ventricular rupture contained by adherent pericardium and fibrotic tissue. Pseudoaneurysm is thus characterized by the absence of myocardial tissue in its wall and a relatively narrow ostium between the ventricle and the paraventricular chamber (Fig 1). The plain-film finding of a paracardiac mass in a diaphragmatic or posterolateral location (Fig 2) in conjunction with a history of previous myocardial infarction is highly suggestive of pseudoaneurysm and is sufficient indication for angiographic studies.<sup>3,4</sup>Left ventriculography will show a paraventricular chamber filling via a relatively narrow ostium. The diagnosis is confirmed by demonstrating an avascular wall on coronary arteriography.<sup>4</sup> <h3>Report of a Case</h3> A 62-year-old man was admitted for syncope and
THE METABOLISM OF CALCIUM AND PHOSPHORUS IN RICKETS
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
NEW LIFE MEMBERS
Journal: Annals of Internal Medicine (1959)

College News Notes1 March 1959NEW LIFE MEMBERSAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-50-3-clxv SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe College acknowledges with pleasure the following new Life Members:Dr. Charles Bohnengel, Toledo, OhioDr. Marvin B. Day, Hartford, Conn.Dr. Charles F. Downing, Decatur, Ill.Dr. Arthur F. Edwardes, Los Angeles, Calif.Dr. Lawrence H. Gahagan, New York, N. Y.Dr. Samuel B. Hadden, Philadelphia, Pa.Dr. John D. Hallahan, Media, Pa.Dr. Irving I. Lasky, Beverly Hills, Calif.Dr. Irene F. Laub, Easton, Pa.Lt. Col. William H. Meroney, (MC), USADr. C. Edward Rankin, Lexington, Ky.Dr. Albert Segaloff, New Orleans, La.Dr. David C. Thurber, Rochester, N. Y.Dr. Harry F. Zinsser, Philadelphia, Pa.BOOKS This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 March 1959Volume 50, Issue 3Page: clxv-clxxxii ePublished: 1 December 2008 Issue Published: 1 March 1959 PDF downloadLoading ...
Cardiorespiratory complications in a cardiovascular laboratory. Anesthesiologists' view
Authors: R. O. Lundborg
Journal: JAMA (1967)

An analysis was made of 1,554 patients over a two-year period. Procedures performed included cardiac catheterization, angiocardiography, arteriography, cardioversion, and catheter-electrode placement. Of the 72 significant complications that developed, 59 (82%) were circulatory in origin. Four patients died (0.3%), three of whom were less than 2 months of age. Nine procedures were discontinued because of complications.
Correction
Journal: BMJ (1960)

ANY QUESTIONS?MDICJOR Of these the toxic effects of triorthocresyl phosphate are best known.If ingested it causes peripheral neuritis, and it is the substance responsible for the recent tragic outbreak in Morocco.2Cases of poisoning due to inbalation have also been reported,3 and it is believed that sufficient triorthocresyl phosphate can be absorbed through human skin to constitute a real hazard in processes in which this compound is used repeatedly.'Carbon tetrachloride is probably the best known of the three substances as an industrial poison.The dangers of inhalation are less well recognized than those of ingestion.A concentration of 1 part of carbon tetrachloride in 1,000 parts of air is said to be the upper limit of safety, and this may easily be exceeded if solutions containing carbon tetra- chloride are in frequent use in a poorly ventilated room.Small doses may give rise to drowsiness, headache, nausea, *and vomiting, and chronic poisoning may result in acute nephritis, toxic hepatitis, jaundice, and aplastic anaemia.Straus' reported three fatal cases of aplastic anaemia occur- ring in patients whose work had involved the use of carbon tetrachloride as a cleaning fluid in premises with poor ventilation, and the writer has recently seen a case of acute renal failure, fortunately not fatal, which followed the inhalation of fumes of carbon tetrachloride when a bottle containing cleaning fluid broke in a small ship's cabin.This will give some idea of the possible dangers which may arise as a result of the use of these substances.Fortunately, although photocopying is now a common procedure, it is in only special circumstances that the process which may involve the use of these chemicals is required.This is the process of " transparentizing," in which a solution is applied to a document which has become opaque through age or handling so that it has to be made more transparent before copying.Although these toxic agents may be used in transparentizing fluids their use for this purpose is apparently uncommon.'It is obvious that if they are to be used then the strictest precautions should be taken.The premises should be adequately ventilated, the solutions used should be clearly labelled and marked "poison," and the personnel employed on the work should be fully aware of the hazards involved.Provided this is done the risks are not any greater than those run in many modern industrial processes which involve the use of such potentially toxic chemical agents.
Highlights
Journal: JAMA Internal Medicine (2015)

LESS IS MORE Dual Use of VA and Medicare Benefits and Use of Test Strips 26Veterans with dual VA and Medicare benefits have access to glucose test strips through both systems, raising the potential for overuse.Gellad and colleagues examined a national cohort of 363 996 VA patients 65 years and older with diabetes who received glucose test strips in 2009.Overall, 71.6% received test strips from the VA only, 22.8% from Medicare only, and 5.6% from both VA and Medicare (dual users).Dual users received 3 times as many test strips in a year as those receiving from VA only and 1.5 times as many as those receiving from Medicare only.Among patients taking no diabetes medications, for whom daily self-monitoring is rarely indicated, 55.4% of dual users received more than 1 test strip daily compared with 15.8% of VA only users.The odds of overuse were greater for dual users compared with both Medicare only and VA only users across all medication groups.
Triamterene, a New Diuretic Drug
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Force of Habit
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PROPOSED HEALTH DEPARTMENT FOR THE GREATER NEW YORK.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Errors in Dosage Equivalents
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal