tbuckley/cabot-search huggingface dataset:
Abstract 125: Steroid Treatment in the Acute Phase of Kawasaki Disease in Mexican Children. Are they Useful?
Authors: Miguel Garcia-Dominguez, Luis M Garrido-Garcia
Journal: Circulation (2015)

Background: Intravenous immunoglobulin (IVIG) and aspirin is the standard initial therapy in the treatment of Kawasaki disease (KD), which is proven to decrease the incidence of coronary artery aneurysms from 25% to less than 5%. There is increasing evidence for steroid therapy as adjunctive primary therapy with IVIG especially in those patients who are at increased risk of coronary artery aneurysms and in patients with risk of IVIG resistance. However, clinical trials evaluating the use of corticosteroids plus IVIG have produced confusing results. Objective: To evaluate the clinical efficacy and safety of steroids plus intravenous immunoglobulin (IVIG) combination therapy (IVIG+S) for the initial treatment of patients with KD to prevent coronary artery aneurysms (CAA) compared with the standard treatment with intravenous immunoglobulin plus aspirin (IVIG+A) in a Children’s Hospital in Mexico City. Material and Methods: An observational, comparative, retrospective and case-control study of all patients treated with IVIG for KD in our Institution from August 1995 to May 2014. The clinical presentation, laboratory results and coronary artery abnormalities in the IVIG+S and the IVIG+A groups were analyzed and compared. Results: We studied 295 patients with KD treated with IVIG, 136 (46.1%) received IVIG+A treatment and 159 (53.9%) received IVIG+S treatment. We didn’t found adverse reactions in the patients treated with steroids. The IVIG+S group were older 43.25 ± 43.04 than the non-steroid group 32.07 ± 24.51 (p &lt; 0.008). Steroids were commonly use in incomplete cases (p &lt; 0.059) and in patients with cardiac complications at diagnosis: pericardial effusion (p &lt; 0.056) and pericarditis (p &lt; 0.013). The steroid group has slightly more days of fever after the IVIG treatment 1.27 ± 1.51 days vs. 0.93 ± 0.924 days (p &lt; 0.028). We found no difference in the development of CAA in both groups. (p = 0.221) Conclusions: There were no differences in the development of CAA with the use of steroids in the initial treatment of KD. Nevertheless steroids were used more commonly in incomplete forms of KD and in more severely affected patients, which could reflect the lack of difference in the development of CAA in both groups.
Pediatric Nursing
Authors: Robert G. Frazier
Journal: JAMA (1960)

In this fourth edition of her basic textbook, the author stresses the fundamental importance to the pediatric nurse of knowledge about the child as a whole both in health and in disease, the diseases which affect children, and the basic nursing skills involved in treating sick children. It is appropriate in a textbook of this sort that greatest emphasis has been given to a careful description of basic skills and procedures that should be included among the capabilities of a pediatric nurse. Much space is devoted to an understanding of the physical and mental growth of the child and the factors that contribute to mental and emotional health. The importance of the nurse's understanding of the basic drives, needs, and fears that determine a child's behavior is eloquently shown in sections discussing the reactions and thoughts of children and of parents in various situations in a hospital or doctor's office.
Rabies Vaccine
Authors: Joan Stephenson
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Estrogen use and cancer risk
Authors: M. B. Lipsett
Journal: JAMA (1977)

DURING the last two years, the lay public and the medical profession have seen a series of reports about the safety and risk of estrogens and oral contraceptives, the toxicities attributed to diethylstilbestrol, the hazards of conjugated estrogens, and several related topics. The pressures for some sort of action have often been so intense that the Senate at one time passed legislation barring the use of a particular synthetic estrogen, diethylstilbestrol. The effects of the estrogens on cancer have been presented and interpreted by epidemiologists, biochemists, gynecologists, and endocrinologists, each with a different perspective and often with differing conclusions. The physician must be prepared to discuss these issues with patients, the public, and those who influence legislative bodies and regulating agencies. It seems worthwhile, therefore, to address some of the basic issues relating to estrogens and cancer with the intention of making the physician able to judge the worth and
Allied health education and accreditation
Authors: W. R. Burrows
Journal: JAMA (1986)

<h3>MUTUAL SUPPORT: AMA AND THE ALLIED HEALTH PROFESSIONS</h3> Allied health professionals are described in US Public Law 99-129 as persons who share in the responsibility for the delivery of health care services or related services, including services relating to the identification, evaluation, and prevention of diseases and disorders; dietary and nutrition services; health promotion services; rehabilitation services; or health systems management services. The article that follows discusses the goals and methods of various bodies that collaborate under the umbrella of the Committee on Allied Health Education and Accreditation (CAHEA) to accredit allied health educational programs in a rapidly changing health care environment. For more than 50 years, the American Medical Association (AMA) and its members have recognized the value of participating extensively in various activities to promote quality education for allied health personnel. Many physicians are involved in allied health educational programs, as well as in the accreditation review process
AGE AND CAUSE OF DEATH OF SCHIZOPHRENIC PATIENTS
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gonococcal Cultures
Authors: Jane Polkowski
Journal: JAMA (1977)

<h3>To the Editor. —</h3> After reading the article by Feng et al (237:896, 1977), Wayne County Health Department Venereal Disease Clinic did a correlation study between the urethral swab and first-voided urine methods of obtaining gonococcal cultures on some male patients. A urethral swab specimen was taken for Gram stain and culture prior to obtaining the urine specimen. A sterile cotton-tipped applicator was dipped into approximately 20 ml of first-portion urine voided into a styrofoam cup (marked with pen on the outside at about 20 ml) and plated within ten minutes of voiding. One half of the same modified Thayer-Martin (TM) plate was streaked by each method per patient. Of 154 TM culture plates, 125 were negative by both methods, 28 were positive by both, and one was positive by the urine method but negative by the urethral swab method. One hundred twelve men had Gram-stained urethral smears in addition
CONGENITAL SQUINT.
Authors: WILLIAM CAMPBELL POSEY
Journal: JAMA (1907)

Like all other phases of the muscle problem, that of which I treat in this paper can scarcely be said to be solved; indeed, it may well be doubted if a distinct discrimination is always made between this variety of strabismus and concomitant squint. It is not easy in infants and young children to detect a limitation in the movement of an eye, which is the usual diagnostic point of difference between congenital and concomitant squints, though it will be remembered that while in concomitant squint the deviation of the ocular axes persists as the eyes are moved through the different meridians of the field of fixation, the degree of the deviation remains constant, and the angle of the squint is always the same, whereas in congenital squint the degree of the deviation and the angle of the squint vary according as the eye with the defective muscle or muscles
Fate
Authors: Jason D. Eubanks
Journal: Annals of Internal Medicine (2010)

Ad Libitum1 June 2010FateJason D. Eubanks, MDJason D. Eubanks, MDFrom University Hospitals Case Medical Center, Cleveland, OH 44106.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-152-11-201006010-00029 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Maybe it is a simple roll of the diceAnd this is the number you drew,Hands and feet shackledAs they wheel you into the operating room.Five minutes before,Nakedly gowned in the preop area,Your spirit was supple in its fear,No hint of indurated, lifetime crime,A man caged behind high security walls,Escorted by guards, lineman bodies fitWith arms the diameter of my thighs …A necrotic mass ... Author, Article, and Disclosure InformationAffiliations: From University Hospitals Case Medical Center, Cleveland, OH 44106.Current Author Address: Jason D. Eubanks, MD, Department of Orthopaedic Surgery, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byConstitutional Rights in the Machine Learning State 1 June 2010Volume 152, Issue 11Page: 760KeywordsBreathingCrimeFearLungsSpineSurgeonsSurgeryWalking ePublished: 1 June 2010 Issue Published: 1 June 2010 Copyright & PermissionsCopyright © 2010 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Cohen Reintroduces Loan Deferment Bill
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Commentary
Authors: Marc Barthet
Journal: Endoscopy (2021)

This e-Video from Hashimoto et al. shows a salvage endoscopic ultrasound (EUS)-guided rendezvous technique for treatment of disconnected pancreatic duct syndrome (DPDS). The incidence of DPDS amongst patients with severe acute necrotizing pancreatitis ranges between 16% and 46.3% and may be increased by endoscopic necrosectomy procedures [1]. Endoscopic management is now a first-line treatment since percutaneous drainage and surgery have greater morbidity, with a high fistula rate. EUS-guided treatment allows transmural drainage of associated pancreatic fluid collections (PFCs) with a 90% success rate, whereas transpapillary drainage of the disrupted duct has a success rate in less than 50% of cases. The usual option is to leave two double-pigtail stents in place in the PFC to definitively drain the upstream pancreatic duct. Hashimoto et al. demonstrate a new EUS-guided rendezvous technique to treat the disrupted pancreatic duct, and as shown in the video, treatment must await for dilatation of the upstream wirsung duct. EUS offers a new potential for managing all the complications of acute necrotizing pancreatitis.
JAK1/2 and BCL2 Inhibitors Synergize to Counter-Act Bone Marrow Stromal Cell-Induced Protection of AML
Authors: Riikka Karjalalainen, Tea Pemovska, Muntasir Mamun Majumder, Bhagwan Yadav, Jing Tang, Mika Kontro, Bjørn Gjertsen, Alun Parsons, Minna Suvela, Kimmo Porkka, Tero Aittokallio, Olli Kallioniemi, Krister Wennerberg, Jonathan Knowles, Caroline Heckman
Journal: Blood (2015)
Acute exposure of cotton dust. A case of mill fever
Authors: D. L. Holness
Journal: JAMA (1982)

EXPOSURE to cotton dust may cause several syndromes, the best known of which is byssinosis.<sup>1</sup>Another syndrome occurring principally in persons unaccustomed to cotton dust exposure is mill fever, which consists of fever, chills, cough, and malaise and which may recur with further exposures until tolerance develops over weeks or months. In 1940 Trice<sup>2</sup>described the symptoms of mill fever in persons carding low-grade cotton, but no measurements were included. In 1942 Neal and co-workers<sup>3</sup>described similar symptoms in rural mattress makers and proceeded to investigate the effects of low-grade cotton on exposed subjects under experimental conditions. Despite these early reports, mill fever has received scant attention in the scientific literature, and recent studies of cotton exposure have not drawn attention to the acute effects.<sup>4,5</sup>Moreover, the important relationship of mill fever to byssinosis remains poorly defined. Following a recent visit to a cotton garnett, by
Predictors of Airborne Endotoxin in the Home
Authors: Ju-Hyeong Park, Donna L. Spiegelman, Diane R. Gold, Harriet A. Burge, Donald K. Milton
Journal: Environmental Health Perspectives (2001)

We identified home characteristics associated with the level of airborne endotoxin in 111 Boston-area homes enrolled in a cohort study of home exposures and childhood asthma, and we developed a predictive model to estimate airborne endotoxin. We measured endotoxin in family-room air and in dust from the baby's bed, family room, bedroom, and kitchen floor. Level of airborne endotoxin was weakly correlated (r < 0.3) with level of endotoxin in each of the four types of dust samples and was significantly correlated with endotoxin in family-room dust (p < 0.05). Endotoxin in family-room dust accounted for < 6% of the variability of airborne endotoxin. In a multivariate model, certain home characteristics were positively (p < 0.05) associated with airborne endotoxin. These included current presence of dog (difference in level, dog vs. no dog = 72%, partial R(2 )= 12.8%), past presence of dog (partial R(2) = 5.5%), and endotoxin level in family-room dust (partial R(2) = 5.3%). Use of a dehumidifier (partial R(2) = 6.4%) was negatively associated (p = 0.02; difference = -31%) with airborne endotoxin. Other home characteristics were identified as important determinants of increased airborne endotoxin in this model, but individual coefficients were not statistically significant (alpha = 0.05): total amount of fine dust collected in the home (partial R(2 )= 3.8%), concrete floor in family room (3.7%), water damage (3.6%), and use of cool-mist humidifier in past year (2.7%). This multivariate model explained 42% of the variability of airborne endotoxin levels, a substantial improvement over that with dust endotoxin alone. Airborne endotoxin in Boston-area homes appears to be determined by the presence of dogs, moisture sources, and increased amounts of settled dust.
Safe and effective treatment of acute liver failure by allogeneic transplantation of stem cell-derived encapsulated liver tissue without immunosuppression
Authors: Claudia Raggi, Marie-Agnès M’Callum, Quang Toan Pham, Silvia Selleri, Basma Benabdallah, Christian Beauséjour, Elie Haddad, Massimiliano Paganelli
Journal: Journal of Hepatology (2020)
Recommended method for the determination of plasma corticosteroids. Report by a Medical Research Council working party.
Authors: V James, D Mattingly, J Daly
Journal: BMJ (1971)

The determination of plasma cortisol offers a useful means of investigating adrenocortical function, and several valuable diagnostic procedures have evolved on this basis and are becoming increasingly widely used.These procedures often offer considerable advantages over methods requiring urinary steroid analysis, and thus a growing number of clinical
High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2
Authors: Giovanna Maria Pierantoni, Cinzia Rinaldo, Marcella Mottolese, Anna Di Benedetto, Francesco Esposito, Silvia Soddu, Alfredo Fusco
Journal: Journal of Clinical Investigation (2013)

It has come to our attention that multiple HMGA1 bands in the immunoblot images of Figure 1,A,B, and D, and Figure 3D have been inappropriately duplicated.In addition, the p53 blots in Figure 1, A and B, appear to represent a darker exposure of the same blot.
Can we accurately identify chemotherapy-related acute care visits in administrative data?
Authors: Monika K Krzyzanowska, Katherine Enright, Rahim Moineddin, Lingsong Yun, Mohammed Ghannam, Eva Grunfeld
Journal: Journal of Clinical Oncology (2014)

6515 Background: Administrative data is increasingly being used to study treatment related complications that lead to acute care visits such as emergency department visits or hospitalizations (ED+H). We evaluated the accuracy of billing codes for identifying chemotherapy related acute care visits (CRVs) among women with breast cancer. Methods: We prospectively developed an algorithm to identify CRVs from administrative data in women receiving adjuvant chemotherapy for breast cancer in Ontario, Canada. Sensitivity (SN) and specificity (SP) were calculated for 3 scenarios: chemotherapy related ED visit, chemotherapy related H, and febrile neutropenia (FN) related visit using the chart as the gold standard. Since there is no specific billing code for FN, three different definitions of FN were considered: liberal (defined as fever or infection or neutropenia as main reason for visit), moderate (neutropenia as main reason for visit) or strict (fever or infection plus neutropenia). The population based cohort was generated by linking several health databases to identify women who had at least one ED+H during adjuvant chemotherapy for breast cancer between 2007-2009. The validation cohort consisted of 496 randomly selected cases from this cohort. Results: The population-based cohort consisted of 8,359 patients of whom 43.4% had at least one ED+H including 1496 women who had multiple visits resulting in 6293 unique ED+H. Of these, 73.1% were considered CRVs based on our algorithm. The algorithm performed well in identifying CRVs that included an H either from ED (SN 90%, SP 100%) or directly from home (SN 91%, SP 93%) but less well for ED visits that did not result in H (SN 65%, SP 80%). Depending on which FN algorithm was used, 4.8-24% of visits were considered FN related. The liberal FN algorithm had excellent SN regardless of whether the visit involved H (94-98%) but SP was moderate (64-80%). The strict FN algorithm had good SP (79-99%) but SN was highly variable (13-89%). The moderate FN algorithm provided the best tradeoff between SN (69-97%) and SP (83-98%). Conclusions: CRVs can be identified from administrative data with reasonable confidence, obviating the need for chart abstraction to evaluate chemotherapy related serious events.
Targeted Beacopp Variants in Patients with Newly Diagnosed Advanced Stage Classical Hodgkin Lymphoma: Final Analysis of a Randomized Phase II Study
Authors: Peter Borchmann, Dennis A. Eichenauer, Annette Pluetschow, Heinz Haverkamp, Stefanie Kreissl, Michael Fuchs, Martin Soekler, Johannes C. Hellmuth, Julia Meissner, Stephan Mathas, Karolin Behringer, Markus Dietlein, Carsten Kobe, Volker Diehl, Andreas Engert
Journal: Blood (2015)
Proceedings of the Thoracic Society
Journal: Thorax (1970)

The Problem in Developed Countries JOHS HOLM A review of the problem as seen by an international medical administrator.BBTA National Mortality Survey P. D. B. DAVIES There are still over 2,000 deaths attributed to tuberculosis in England and Wales each year, and 250% of these are first diagnosed at necropsy.The Research Committee of the BTTA has therefore con- ducted an enquiry to try to determine (a) whether these deaths can be strictly attributed to active tuberculous disease or its treatment and might therefore have been preventable; and (b) the nature of any avoidable factors, both clinical and administrative, which contri- buted to these deaths.A copy of every death certificate in which tuberculosis appeared issued in England and Wales between February I and April 30 1968 was sent to the local chest physician, who was asked to carry out an enquiry into the death, to complete an extensive questionnaire and to return it to the Research Committee of the BTTA for analysis.The results of this analysis of 884 cases form the basis of this preliminary report.A Reappraisal of Control Measures I. SUTHERLAND This is a report of recent work carried out by the International Tuberculosis Surveillance Research Unit with comments on features of this work which suggest that a reappraisal of tuberculosis control measures may now be appropriate in the so-called developed countries.Surveillance in Countries with Low Prevalence J. CROFTON The apparently paradoxical situation that most tuberculous infection, for each particular cohort, occurs in childhood is not really surprising if one bears in mind the much smaller risk of infection in each succeeding cohort.One could put the paradox in another way: the older a patient is when he develops disease the younger he is likely to have been when he was first infected.Arising out of these observations there are three problems which require thought: (1) the specificity of the Heaf test, the main test now used in the U.K.;