tbuckley/cabot-search huggingface dataset:
Intraaortic balloon pumping improves left ventricular function but not prevents remodeling in patients with microvascular reperfusion injury after anterior wall acute myocardial infarction Satoshi Kurisu, Hikaru Sato, Takuji Kawagoe, Masaharu Ishihara, Yuji Shimatani, Kenji Nishioka, Yasuyuki Kono, Suji Nakamura, Takashi Unemura. Hiroshima City Hospital, Hiroshima, Japan
Journal: Journal of the American College of Cardiology (2001)
Associations of Blood Levels of PCB, HCHs, and HCB with Numbers of Lymphocyte Subpopulations, in Vitro Lymphocyte Response, Plasma Cytokine Levels, and Immunoglobulin Autoantibodies
Authors: Volker Daniel, Wolfgang Huber, Klausdieter Bauer, Caner Suesal, Christian Conradt, Gerhard Opelz
Journal: Environmental Health Perspectives (2001)

Pentachlorophenol (PCP), hexachlorocyclohexane-[alpha], -beta, and -[gamma] (HCH-[alpha], -beta, and -[gamma]), polychlorinated biphenyls (PCBs), and hexachlorobenzene (HCB) are widely distributed industrial chemicals. They are suspected to induce immunologic impairments in exposed individuals. We examined dose-response relationships of blood levels of these chemicals with cellular (numbers of lymphocyte subpopulations, in vitro lymphocyte response) or humoral (plasma cytokine levels, immunoglobulin autoantibodies) immunologic dysfunctions. We studied 146 patients who had been occupationally exposed primarily to PCBs for more than 6 months. Lymphocyte subpopulations, in vitro responses to mitogens and allogeneic stimulator cells, plasma neopterin, cytokines, soluble cytokine receptors, soluble adhesion molecules, anti-Ig autoantibodies, and liver transaminases were determined. Blood levels of the different compounds were strongly correlated with one another. There were only weak dose-response relationships between blood levels of PCBs with cellular immune parameters, and of HCHs and HCB with humoral immune parameters. An exception was the statistically significant negative association of HCB with interferon-[gamma] (IFN-[gamma]), indicating that HCB has a significant impact on Th1 lymphocytes. Patients with HCB blood levels above the mean of 1,109 ng/L more often had undetectable IFN-[gamma] blood levels than patients below the mean. Patients with increased PCB 138 (> 710 ng/L) had more frequently undetectable interleukin-4 blood levels than patients with PCB 138 below the mean, and patients with increased PCB 101 (> 31 ng/L) more often had low DR+ cell counts in the blood (< 190/microL) than patients with PCB 101 below the mean. To assess possible cumulative effects, we compared patients who had blood levels of all compounds below background with patients who had blood levels of all compounds above background. Patients with low or absent blood levels of the compounds studied had higher IFN-[gamma] plasma levels, providing some evidence for a cumulative effect of several weakly active compounds. In conclusion, exposure to PCBs, HCB, or HCHs is associated with weak immunologic abnormalities. These results contrast with those obtained in earlier studies of blood levels of PCP, which showed a strong dose-dependent relationship with immunologic impairments. Our data suggest that long-term exposure of patients to HCB suppresses IFN-[gamma] production.
Chicago Surgeons Not on Tour.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Processing Use, and Characterization of Shale Oil Products
Authors: Andrew W. Decora, Robert D. Kerr
Journal: Environmental Health Perspectives (1979)

Oil shale is a potential source of oil that will supplement conventional sources for oil as our needs for fossil fuels begin to exceed our supplies. The resource may be mined and processed on the surface or it may be processed in situ. An overview of the potential technologies and environmental issues is presented.
Day care for cancer patients
Authors: E. Ratkowski
Journal: JAMA (1974)

During the six years of its existence, the Hadassah University Hospital "day-care" unit has proved its value as an additional service of the Oncological Center. A total of 188 patients were treated by the service during a six-month observation period, with about 20 patient-visits each day. Sixty percent of the patients received chemotherapy. All reacted favorably to the service, which gave them the opportunity to extend their useful life. (<i>JAMA</i>230:430-431, 1974)
Industrial Exhibits
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fifty Years in Medicine
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reanalysis of the Effects of Air Pollution on Daily Mortality in Seoul, Korea: A Case-Crossover Design
Authors: Jong-Tae Lee, Joel Schwartz
Journal: Environmental Health Perspectives (1999)

We used the case-crossover design to identify any increase in mortality in Seoul, Korea, when there were higher levels of ambient air pollution on case-days than would be expected solely as a result of chance. This empirical study showed that either unidirectional retrospective (selecting only control days prior to death) or prospective (selecting only control days after death) control sampling could cause risk estimates to be confounded by seasonal waves as well as time trends in air pollution levels. In bidirectional control sampling in which exposures at death were compared with exposures both before and after death, the estimated mortality was resistant to confounding by time patterns of air pollution. Using a bidirectional control sampling approach, the results from a conditional logistic regression model controlling for weather conditions showed that the nonaccidental mortality associated with a 50-ppb increment over a 3-day moving average of SO(2) concentrations, including the concurrent day and preceding 2 days, was 1.023 [95% confidence interval (CI), 1.016-1.084]. The relative risk of death was 1.023 (CI, 0.999-1.048) per 50 ppb for 1-hr maximum O(3) and 1.010 (CI, 0.988-1.032) per 100 microg/m(3 )or total suspended particulates. In conclusion, the findings of this study were 2-fold: given the consistency of the observed association between SO(2) and daily mortality across different analysis methods, the association reported here indicates that air pollution is a probable contributor to premature death; and bidirectional control sampling is needed in a case-crossover design applied to air pollution epidemiologic studies to control confounding by seasonal patterns of air pollution as well as time trends.
SYMPOSIUM ON PULMONARY AND CARDIAC DISEASES
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Psychiatric Diagnosis
Authors: Judith S. Yongue
Journal: JAMA (1990)

Donald Goodwin and Samuel Guze, both highly effective and extremely knowledgeable, are physicians and leaders in psychiatry who have presented an excellent and concise compendium of current knowledge with abundant citations. This fourth edition of<i>Psychiatric Diagnosis</i>is a small volume but contains over 1000 references to bolster the stated goal of diagnostic clarification.<i>Psychiatric Diagnosis</i>was a forerunner of the<i>DSM-III</i>, and the authors were intimately connected with the Washington University Department of Psychiatry, which has a reputation of having a strong alliance with biology, taking a medical view of psychiatric illness, and placing heavy reliance on reproducible data. The fourth edition utilizes the<i>DSM-III-R</i>diagnostic categories as a basis of classification and conceptual organization. According to the authors, classification has two functions: communication and prediction. As psychiatry becomes more scientifically oriented it is hoped that more specific treatment can be obtained and more accurate prognosis achieved through a
BOOK REVIEWS
Authors: JOHN S. MACDONALD
Journal: JNCI Journal of the National Cancer Institute (1992)

Journal Article BOOK REVIEWS Get access Diagnostic Assays for Colon Cancer Abulkalam M. Shamsuddin . Boca Raton, Fla. : CRC Press , 1991 . 133 pp., illus. $69.95 JOHN S. MACDONALD JOHN S. MACDONALD Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 84, Issue 15, 5 August 1992, Pages 1206–1207, https://doi.org/10.1093/jnci/84.15.1206-a Published: 05 August 1992
Pancreatic Enzyme Replacement Products
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AUTHOR'S REPLY
Authors: D. Harrison
Journal: Thorax (1989)

Wegener's granulomatosis Positive (F) ANCA test Negative (F) Negative (D) Diagnostic specificity P(DIF) = 18/21 86% Diagnostic sensitivity P(IDF) = 214/219 98% Positive (D) 18 SI," s 2 1 ~~~~9 Nosological Nosological sensitivity specificity P(FID) = 18/23 P(F/D) = 214/217 78% 99%Nosological and diagnostic sensitivity and specificity of the test for antibodies to neutrophil cytoplasmic antigens (ANCA) used to assess the likelihood of disease according to the result of the test so long as the probabilities of disease in the diagnostic setting and in the patients studied for the paper are similar.On the other hand, nosological values of sensitivity and specificity are of limited direct relevance to the practising physician, who would need to convert these probabilities to the clinically relevant probabilities using Bayes's formula.This conversion is to a large extent dependent on the prior probability of disease in the clinical population studied and this is rarely known.There is a lot to be said for collecting data in a realistic clinical setting, as the authors have done, and quoting diagnostic specificity and sensitivity, rather than evaluating a new test in a group ofpatients who are known to have the disease in question and comparing this with the results in a group of normal people.In these circumstances the nosological value would be more appropriate.Taking the bright, coarsely granular pattern as positive, the authors found that the result of the test was positive in 18 patients with Wegener's granulomatosis and in three who did not have the disease.The result was negative in five patients who had active Wegener's granulomatosis and in 214 other patients, in most of whom, from the limited details given, Wegener's granulomatosis might have been initially suspec- ted but was not subsequently confirmed.On the basis ofthese figures (table) the nosological sensitivity is 78%, the nosological specificity 99%, the diagnostic sensitivity 98%, and the diagnostic specificity 86%.It would seem that the authors have quoted the nosological sensitivity with the diagnostic specificity.I would suggest that it would be more appropriate for them to have quoted the diagnostic sen- sitivity of98%-which, as an added bonus, looks even better than the quoted sensitivity of 78%.
A peculiar cutaneous reaction to repeated injections of insulin
Authors: L. Erickson
Journal: JAMA (1969)

A bizarre skin lesion consisting of a collection of brown, hyperkeratotic papules appeared on the thighs of a 51-year-old diabetic man, after repeated insulin injections into the same area over a period of two or more years. The reason for the development of this type of lesion instead of the usual lipodystrophy that follows multiple insulin injections is obscure.
Protists and Disease. Vegetable Protists; Algae and Fungi, Including Chytridiineae; Various Plassomyxineae, the Causes of Molluscum Contagiosum, Smallpox, Syphilis, Cancer and Hydrophobia; Together with the Mycetozoa and Allied Groups.
Journal: JAMA (1923)

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Use of state risk-pools in protecting the uninsured
Authors: B. R. Tresnowski
Journal: JAMA (1988)

THE COUNCIL on Medical Service report, "Protecting the Uninsured: Use of State Risk-Pools,<sup>1</sup>is a useful contribution to an unsolved national problem. We at the Blue Cross and Blue Shield Association share the American Medical Association's commitment to finding answers that will make the best use of all that the entire health care financing system can offer. The problem of the uninsured is a challenging one, and solutions will necessarily involve sharing responsibilities of both the public and private sectors. We share the American Medical Association's commitment to answers that use what we already have in place; for example, the risk pools in 15 states that afford coverage for people with chronic medical conditions that make it impossible for them to get insurance at any price. In those states the pools have been designed to provide coverage to these individuals in a manner that is compatible and not competitive with
Abstract MP68: Populations with Multiple Adverse Behavioral Factors
Authors: Thomas Eckstein, Laura Houghtaling, Mariah Quick
Journal: Circulation (2016)

Traditionally, population behavioral characteristics are reported at the individual level. However, just like diseases, the combination of multiple adverse risk factors, even though they are often highly correlated, presents a different challenge and impact on community health than examining these same behaviors in isolation. We analyzed 5 risk factors in the 2014 Behavioral Risk Factor Surveillance Survey; smoking (currently a smoker), inactivity (no physical activity outside of work), excessive alcohol consumption (for women, 4 or more drinks in one sitting or an average of greater than one drink per day; for men, 5 or more drinks in one sitting or an average of greater than two drinks per day), obesity (BMI &gt;=30), and insufficient sleep (&lt; 7 hours per night). These five measures were selected because of their strong association with heart and other disease. We studied the frequency of multiple factors by state, sex, race, urbanicity, educational attainment and income. The attached map illustrates the variation among states in the prevalence of 3 or more risk factors in the population. In Utah, Colorado, and California, less than 9% of the population has 3 or more; in Arkansas, Louisiana, Kentucky and Mississippi, 16% or more of the population has 3 or more of these risk factors. Among demographic subpopulations, differences also exist. For non-Hispanic Asian population 4.5% (CI:3.5%-5.4%) have 3 or more risk factors compared to 16% or more exhibiting 3 or more risk factors in the non-Hispanic black, non-Hispanic American Indian and Alaskan Native, and non-Hispanic multi-racial populations. The variation among these subpopulations within states was also explored. Understanding the distribution of multiple adverse risk factors within a state’s population can help guide the efforts of public health officials, policy makers, advocacy groups and others to focus on the most affected populations and develop interventions that address multiple related conditions.
Unilateral Glaucoma Following Resection of a Tumor of the Superior Fornix
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treating a Societal Malignancy—Rape
Authors: Don Riesenberg
Journal: JAMA (1987)

A RAPE occurs every six minutes in this country. The articles in this series look at what is known about this societal malignancy and the ways that physicians can help rape survivors. Statistics compiled by Women Organized Against Rape (WOAR) in Philadelphia indicate that the 1020 reported rapes in that city in 1985 represented a 12% increase from the previous year. Karen Kulp, executive director of the 13-year-old organization, says those figures don't tell the whole story: "Conservative estimates are that half of rapes are not reported. The Philadelphia community is concerned about victims getting proper treatment. We [WOAR] have pushed the process along by forming a citywide Sexual Assault Program, which convenes quarterly. Treatment for rape victims is now free in Philadelphia; this is not the case in many cities." Barbara Rohne, RN, a staff nurse at Thomas Jefferson University Hospital, where many Philadelphia rape victims are brought for