tbuckley/cabot-search huggingface dataset:
Table of Contents
Authors: Jeremy Leventhal, Michael Ross, Girish Nadkarni, Steven Coca, Christina Wyatt, Dale Abrahamson, Maria Luisa, S Sequeira-Lopez, Elena Torban, Teresa Chen, Michelle Estrella, Hamid Moradi, Hamid Said, Claudio Rigatto, Paul Komenda, Navdeep Tangri, Michael Brier, Adam Gaweda, Christiane Peuckert, Bejan Aresh, Pavlo Holenya, Derek Adams, Smitha Sreedharan, Annika Porthin, Louise Andersson, Hanna Pettersson, Stefan Wölfl, Rüdiger Klein, Leif Oxburgh, Klas Kullander, Lijun Ma, Carl Langefeld, Mary Comeau, Jason Bonomo, Michael Rocco, John Burkart, Jasmin Divers, Nicholette Palmer, Pamela Hicks, Donald Bowden, Janice Lea, Jenna Krisher, Margo Clay, Barry Freedman, Fang Zhang, Jinit Masania, Attia Anwar, Mingzhan Xue, Daniel Zehnder, Hemali Kanji, Naila Rabbani, Paul Thornalley, Bjørn Eriksen, Vidar Stefansson, Trond Jenssen, Ulla Mathisen, Jørgen Schei, Marit Solbu, Tom Wilsgaard, Toralf Melsom, David Charytan, Manisha Desai, Maya Mathur, Noam Stern, Maria Brooks, Lukasz Krzych, Gerhard Schuler, Jan Kaehler, Alfredo Rodriguez-Granillo, Whady Hueb, Barnaby Reeves, Holger Thiele, Alfredo Rodriguez, Piotr Buszman, Paweł Buszman, Rie Maurer, Wolfgang Winkelmayer, Carlo Barbieri, Manuel Molina, Pedro Ponce, Monika Tothova, Isabella Cattinelli, Jasmine Titapiccolo, Flavio Mari, Claudia Amato, Frank Leipold, Wolfgang Wehmeyer, Stefano Stuard, Andrea Stopper, Bernard Canaud, Anne Blanchard, Emmanuel Curis, Tiphaine Guyon-Roger, Diana Kahila, Cyrielle Treard, Véronique Baudouin, Etienne Bérard, Gérard Champion, Pierre Cochat, Julie Dubourg, Renaud De La Faille, Olivier Devuyst, Georges Deschenes, Michel Fischbach, Jérôme Harambat, Pascal Houillier, Alexandre Karras, Bertrand Knebelmann, Marie-Pierre Lavocat, Chantal Loirat, Elodie Merieau, Patrick Niaudet, François Nobili, Robert Novo, Rémi Salomon, Tim Ulinski, Xavier Jeunemaître, Rosa Vargas-Poussou
Journal: Kidney International (2016)
Clinical value of circulating epithelial tumor cells and circulating endothelial cells (CTCs/CECs) in patients with HER2-negative recurrent or metastatic breast cancer treated with bevacizumab in combination with paclitaxel (P) and gemcitabine (G) as first-line therapy.
Authors: L. Manso, E. M. Ciruelos, M. Codes, J. R. De la Haba, A. Galan, J. M. Baena, A. Jaen, M. Gil, A. Murias, I. Blancas, E. Gonzalez, D. Perez, J. L. Bayo, J. R. Mel, E. Garcia-Martinez, R. Cubedo, J. Salvador
Journal: Journal of Clinical Oncology (2011)

e21105 Background: Worse prognosis of the presence of CTCs in peripheral blood has been demonstrated in MBC and have potencial to influence the clinical management for pts. Bevacizumab (B) in combination with CT, improves progression free survival (PFS) of first line treatments and may modify tumor cell intravasation and CTC/CEC levels. Methods: Patients received B (10mg/kg/q2w) combined with P 150 mg/m2 and G 2,000mg/m2 d 1 y 15 q28d as first-line therapy, until disease progression, unacceptable toxicity or withdrawal. CTC/CEC were measured in 7.5ml of blood at baseline and after the first cycle of treatment and enumeration was performed by CellSearch System, Veridex LCC. Results: Median of follow-up was 12.94 months. Baseline data were available for 37 pts. We obtained post-treatment CTCs value in 28 pts. The media number of CTCs was 41.5 cells (min 0-max 845) in the 1st determination and 5.61 cells (min 0-max 99) in the 2nd determination, p=0.0075. 89% (N=25) of the pts decreased or maintained post-treatment CTCs value. >5 baseline CTCs was associted with worse PFS (8.8 months) compared to those with <5 (10.8 m), long rank p=0.83. In 36% of the pts (N=10) we found > 5 baseline CTCs and a reduction to < 5CTCs was observed in 70% in the second determination (N=7), p=0.20 (IC 34.15-93.33). 92% (N=22) of pts that had stable disease/partial response, decreased or maintained post-treatment CTCs value. The media value of baseline CECs was 130 cells (min 4- max 1407) and 60.3 cells (min 0-max 349) in second determination, p=0.02. 71% (N=15) of the pts decreased or maintained post-treatment CECs value. 74% (N=14) of pts that had stable disease/partial response, decreased or maintained post-treatment CECs value. 72% of the pts that decreased CTCs value decreased CECs value. CTC level was not correlated with CEC level, p=0.74. Conclusions: The addiction of B to first-line CT was related with high reduction of the value of baseline CTCs and CECs count. In 92% and 74% of pts with clinical benefit, a decreased or maintained post-treatment value of CTCs and CECs was observed respectively.
Monitoring Progress in Arthritis Management—United States and 25 States, 2003
Journal: JAMA (2005)

Arthritis is a chronic disease affecting an estimated 43 million (20.8%) U.S. adults and is the leading cause of disability in the United States. Arthritis results in activity and work limitations, decreased quality of life, and substantial burden to the U.S. health-care system. Promotion of arthritis self-management through weight counseling, physical activity counseling, and arthritis education can reduce pain, improve function and quality of life, and delay disability among persons with arthritis. To encourage arthritis self-management, three objectives were added to the national health objectives for 2010. To monitor progress toward achieving these objectives and assess that progress by selected characteristics, CDC analyzed data from the 2003 National Health Interview Survey (NHIS) and the state-based 2003 Behavioral Risk Factor Surveillance System (BRFSS) survey. This report summarizes the results of those analyses, which indicated no statistically significant progress toward reaching the targets for weight counseling, physical activity counseling, and arthritis education. To meet these targets by 2010, public health and health-care agencies should increase efforts to improve awareness of these three factors among both health-care providers and patients. Such interventions will enable persons with arthritis to better self-manage their disease.
American Journal of Pathology, New York
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
JAMA Reference Directories
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Is it safe to drive SUVs?
Journal: Environmental Health Perspectives (1998)

Since 1992, SREL scientists have made numerous expeditions to Ukraine to study the genetic effects of radiation on the flora and fauna within the Chornobyl Exclusion Zone, which extends 30 km from the plant in all directions.Chesser himself has made some 15 expeditions to Chornobyl.The idea for the laboratory was first raised in the summer of 1993."During my work [at Chornobyl] that summer and since," says Chesser, "I found that many of the samples were too high in radioactivity to transport, and that several important analyses and experimental designs could not be per- formed because of lack of nearby equip- ment and [the short-term nature of the] expeditions."Talks with the Ukrainian government ensued, and in 1996, the Savannah River Operations Office decided to provide fur- ther equipment to aid the research efforts at Chornobyl.Since then, through the efforts of the DOE Office of Nonpro- liferation and National Security, political and logistical arrangements were made that culminated in the agreement signed by U.S. Vice President Al Gore and Ukrainian President Leonid Kuchma.Chesser will serve as director of science programs for the laboratory, and will sit on its governing board.The lab will also employ a director, lab technicians, and field crews.The full-
Hypertension detection and follow-up
Authors: Robert B. Taylor
Journal: JAMA (1980)

<h3>To the Editor.—</h3> The report by the HDFP Cooperative Group presents important evidence in favor of SC of hypertension but raises important issues concerning the influence of life-style change. The report cites a 17% lower five-year mortality for the SC group as compared with the RC group. However, the former group received not only medication but limited counseling concerning weight control, diet, and smoking. Health promotion is a social force that promises to have profound influence on medical care in the future.<sup>1</sup>Epidemiologic studies have shown that health practices can bring a dramatic decrease in mortality. A 45-year-old American man performing six or seven specific health practices has an 11-year greater life expectancy than if he adheres to three or less; the increase in longevity for a 45-year-old woman is seven years.<sup>2</sup>By contrast, all of the new drugs and scientific advances from 1900 to 1970 have increased
MALARIA INVESTIGATION IN THE PACIFIC ISLANDS.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Polybrominated Biphenyl (PBB) Contamination of the Pine River, Gratiot, and Midland Counties, Michigan
Authors: John L. Hesse, Richard A. Powers
Journal: Environmental Health Perspectives (1978)

Michigan Chemical Corporation, St. Louis, Michigan manufactured PBB from 1970 until November 20, 1974. Studies in 1974 showed significant quantities of PBB in effluent discharged from the facility and in water, fish, ducks, and sediments from the Pine River. Fish uptake rates and bioconcentration factors were estimated. Followup surveys over the three year period since the termination of PBB production indicate a decline in PBB loadings to the river but no significant corresponding decline of PBB levels in sediments, fish and duck tissue. A Michigan Department of Public Health warning against consumption of Pine River fish from St. Louis downstream to its confluence with Chippewa River remains in effect.
The Future of Primary Care
Authors: Scott A. Shipman, Jon D. Lurie, David C. Goodman
Journal: Annals of Internal Medicine (2004)

Letters6 January 2004The Future of Primary CareScott A. Shipman, MD, MPH, Jon D. Lurie, MD, MS, and David C. Goodman, MD, MSScott A. Shipman, MD, MPHFrom Oregon Health and Sciences University, Portland, OR 97201; and Dartmouth–Hitchcock Medical Center, Lebanon, NH 03768.Search for more papers by this author, Jon D. Lurie, MD, MSFrom Oregon Health and Sciences University, Portland, OR 97201; and Dartmouth–Hitchcock Medical Center, Lebanon, NH 03768.Search for more papers by this author, and David C. Goodman, MD, MSFrom Oregon Health and Sciences University, Portland, OR 97201; and Dartmouth–Hitchcock Medical Center, Lebanon, NH 03768.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-140-1-200401060-00026 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The Annals supplement on the many challenges confronting the future of primary care was a timely and insightful review by many of the nation's opinion leaders in medicine. However, references to “primary care” in the collective risk overgeneralizing the constituent specialties, namely general internal medicine, family practice, and general pediatrics. While these specialties do share a set of core principles and are influenced by a similar set of political and social factors, their fates may not be fully intertwined. In his editorial (1), Dr. Sox mentioned the declining workforce of primary care physicians, as well as a ...Reference1. Sox HC. The future of primary care [Editorial]. Ann Intern Med. 2003;138:230-2. [PMID: 12558363] LinkGoogle Scholar2. Shipman SA, Lurie JD, Goodman DC. The general pediatrician: projecting future supply and requirements. Pediatrics [In press]. Google Scholar Author, Article, and Disclosure InformationAuthors: Scott A. Shipman, MD, MPH; Jon D. Lurie, MD, MS; David C. Goodman, MD, MSAffiliations: From Oregon Health and Sciences University, Portland, OR 97201; and Dartmouth–Hitchcock Medical Center, Lebanon, NH 03768. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe Future of Primary Care Harold C. Sox The Future of Primary Care Clifton R. Cleaveland The Future of Primary Care Clair Morud Correction: The Future of Primary Care Metrics Cited byCorrection: The Future of Primary Care 6 January 2004Volume 140, Issue 1Page: 69KeywordsForecastingPediatricsPrimary care physiciansSub-specialty care ePublished: 6 January 2004 Issue Published: 6 January 2004 Copyright & PermissionsCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Overdose of Benzodiazepines
Authors: William G. Bissell
Journal: JAMA (1982)

<h3>To the Editor.—</h3> The survey by Carl Chambers, PhD, in the MEDICAL NEWS section concerning the prescribing of minor tranquilizers (1981;246:14) reports that 7% of 150 physicians polled had at least one patient die of overdose from benzodiazepines alone or in combination with alcohol. The proportion of these deaths attributed to benzodiazepines alone is not stated. This is an important distinction in that the preponderance of evidence suggests that deaths owing to benzodiazepines alone are uncommon.<sup>1</sup> In a survey of medical examiners done by Finkle and associates (1979; 429-434), they report on 1,239 overdose deaths involving diazepam. Only two of these were attributed to diazepam alone. Most cases involved two or more substances, and the other drugs found most frequently were alcohol, propoxyphene, and morphine. In a multiple-drug overdose, it has not been determined whether benzodiazepines potentiate, add, or have little contribution to fatal outcome. Certainly the other commonly
JAMA Pediatrics
Authors: Phil Fontanarosa, Annette Flanagin, Brenda Gregoline, Tracy Frey, Shannon Sparenga, Nicole Balin, Miriam Cintron, Paul Ruich, Diane Cannon, Connie Manno, Fred Marshall, Laura Copyreaders, Catherine Adamczyk, Stephanie Alden, Jan Beckmeyer, Mary Clavey, Paula Coerver-Connolly, Roya Glitman, Laura Khatiblou, Donna King, Caroline Thordsen, Wanda Assistant, Larry Bryant, Monica Mungle, Elaine Williams, Lenette Gardner-Gullens, Fanny Brown, Paul Frank, Peter Kim, Rachell Lozano, Michaela Mark, Kathryn Muskovich, Gale Saulsberry, Michael Berkwits, Michelle Kurzynski, Eric Butkus, Will English, Christopher Hastings, Craig Mccaffrey, Reuben Rios, Ronna Henry, Joshua Bird, Karen Bucher, David Song, Deputy Livingston, Thomas Cole, Marla Hall, Deanna Willis, Yolanda Davis, Joseph Thornton, Preeti Malani, Deanna Bellandi, Jim Periodical, Thomas Easley Vice, Brian Shields, Monica Smith, Jeffery Bonistalli Manager, Kathy Russell, Mirna Monal, Tim Melroy, Thalia Moss, Mike Harvey, Susan Henning, Mark Thornbury, Tricia Castellano, Saskia Bolore, Gretchen Linder, Brian Mccartney, David Baum, Rebecca Haas, Christine Hearne, Irma Lara, Ron Marketing, Paul Gee, Matt Herron, Elizabeth Solaro, Geoffrey Flick Managers, Rick Bell, Lindsay Dawson, Michael Mcgraw, Sara Nagy, Romando Rossini, Stacy Staff, Millette Jackson-Bates, Karen Adams-Taylor, Karl Elvin, Sue Managers, David Antos, Chris Borden, Debbie Camp, Lydia Cruz, Scott Curl, Diane Darnell, Colleen Kelly, Chris Meyer, Jaye Mize, Annemarie Neff, J Neff, Sean O'donnell, Sean Ohlson, Phil O'leary, Susan Price, Denise Steinhauser, Production Services, Kim Boler, Rhonda Brown, Timothy Burke, Daniel Degroot, Jordynn Farrar, Euwanaha Joiner-Smith, Tiffany Jones, Cindy Rendlen, Ellen Yoshihara, Circulation Services, Julie Burton, Dexter Golden, Erin Hinchcliff, Maria Nienhaus, Noemi Rivera, Geneine Van, Someren Composition, New Media, Gail Barrett, Regina Brownlee, Amanda Camino, Brenda Chandler-Grayer, Emily Dunn, Amy Evers, Teri Hutchison, Mary Kuranda, Joshua Lampinen, Patricia Panek, La Son, Diggs Sledge, George Thomson Graphics, Joe Amft, Maria Duda, Fred Furtner, Carolyn Hall, Maria Kowalkowski, Proofreading Carol, Joy Farrell, Daniel James, Judith Literskis, Teresa Omiotek, James Madara, Bernard Hengesbaugh, Dimitri Christakis, Washington Joffe, Ron Keren, Debra Palazzi, Suzanne Shuey, Benjamin French, Peter Cummings, Howard Bauchner, Frederick Rivara, Samir Shah, Joyce Lee, Ann Arbor, Jay Berry, Cherrie Boyer, San Francisco, Maria Britto, John Campo, Aaron Carroll, Indiana Frank, Joseph Chaloupka, Mitchell Cohen, Kathleen Janz, Iowa City, Terry Klassen, Michigan Michelle, Huckaby Lewis, Aaron Milstone, Shawn Rangel, Martha Sola-Visner, Jean-Claude Carel, Shabir Madhi, Ben Marais, Frank Oberklaid, Susan Sawyer, Joan-Carles Surís
Journal: JAMA Pediatrics (2015)
The nationwide cancer genome screening project in Japan, SCRUM-Japan GI-screen: Efficient identification of cancer genome alterations in advanced biliary tract cancer
Authors: M. Ueno, C. Morizane, Y. Kawamoto, H. Takahashi, D. Naruge, S. Shimizu, K. Nakamura, T.E. Nakajima, T. Kato, T. Kudo, N. Mizuno, K. Ohtsubo, S. Itoh, H. Ishii, T. Sudo, S. Nomura, S. Fujii, K. Shitara, A. Ohtsu, T. Yoshino
Journal: Annals of Oncology (2017)
Distinct Nanoscale Calcium Channel and Synaptic Vesicle Topographies Contribute to the Diversity of Synaptic Function
Authors: Nelson Rebola, Maria Reva, Tekla Kirizs, Miklos Szoboszlay, Andrea Lőrincz, Gael Moneron, Zoltan Nusser, David A. DiGregorio
Journal: Neuron (2021)
Effects of Applied Pressure and of Positive Acceleration on Photic Driving in Man
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Collaborative survey of perinatal loss in planned and unplanned home births
Journal: BMJ (1996)

<h3>Abstract</h3> <b>Objective</b>: To document the outcome of planned and unplanned births outside hospital. <b>Design</b>: Confidential review of every pregnancy ending in stillbirth or neonatal death in which plans had been made for home delivery, irrespective of where delivery eventually occurred. The review was part of a sustained collaborative survey of all perinatal deaths. <b>Setting</b>: Northern Regional Health Authority area. <b>Subjects</b>: All 558 691 registered births to women normally resident in the former Northern Regional Health Authority area during 1981–94. <b>Main outcome measure</b>: Perinatal death. <b>Results</b>: The estimated perinatal mortality during 1981–94 among women booked for a home birth was 14 deaths in 2888 births. This was less than half that among all women in the region. Only three of the 14 women delivered outside hospital. Independent review suggested that two of the 14 deaths might have been averted by different management. Both births occurred in hospital, and in only one was management before admission of the mother judged inappropriate. Perinatal loss to the 64 women who booked for hospital delivery but delivered outside and to the 67 women who delivered outside hospital without ever making arrangements to receive professional care during labour accounted for the high perinatal mortality (134 deaths in 3466 deliveries) among all births outside hospital. <b>Conclusions</b>: The perinatal hazard associated with planned home birth in the few women who exercised this option (&lt;1%) was low and mostly unavoidable. Health authorities purchasing maternity care need to address the much greater hazard associated with unplanned delivery outside hospital. <h3>Key messages</h3> Only three of 134 deaths were associated with planned home birth Over three quarters of the perinatal deaths asso- ciated with planned home birth occurred in hospi- tal The hazards associated with planned home birth are quantifiable only when death is classified according to the original planned site of delivery Perinatal mortality in the few (&lt;1%) pregnancies in which home birth had been planned was less than half the average for all births, and few of these deaths were associated with substandard care