tbuckley/cabot-search huggingface dataset:
Seat belts in pregnancy.
Authors: M. Pearce
Journal: BMJ (1992)

of heavy and light chains were scrambled to create new, artificial antibodies not represented in the population of human B cells from which the genes were derived.At first sight this may seem to be a disadvantage, but these artificial antibodies may be more likely to recognise human "self' components, as B cells with this property are generally deleted or suppressed by the intact immune system.Many cancer "antigens" and most targets for antibody mediated immunosuppression (lymphocyte surface markers and circulating cytokines) fall into the category of self.The random combinatorial phage library may therefore be a richer source of therapeutically useful antibodies than one that faithfully reproduces the human immune system from which it was derived.Antibodies to human tumour necrosis factor and human immunoglobulin have already been fished out of the library, suggesting that the artificial pairing of antibody variable domains on phage particles really does 1 Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity.
B-Cell Receptor Driven MALT1 Activity Regulates MYC Signaling in Mantle Cell Lymphoma
Authors: Beiying Dai, Michael Grau, Mélanie Juilland, Pavel Klener, Elisabeth Höring, Jan Molinsky, Gisela Schimmack, Sietse M Aukema, Niklas Vogt, Annette M. Staiger, Tabea Erdmann, Wendan Xu, Kristian Erdmann, Wolfgang E Berdel, Marek Trneny, Martin H. Dreyling, Korinna Jöhrens, Peter Lenz, Andreas Rosenwald, Reiner Siebert, Alexandar Tzankov, Wolfram Klapper, Ioannis Anagnostopoulos, Daniel Krappmann, German Ott, Margot Thome, Georg Lenz
Journal: Blood (2016)
Current Status of Marijuana Research
Authors: Gabriel G. Nahas
Journal: JAMA (1979)

REPORTS of the current status of marijuana research were presented at a symposium on marijuana held in July 1978 in Reims, France, under the aegis of the Seventh International Congress of Pharmacology.<sup>1-2</sup>More than 100 scientists from 14 countries attended the meeting sponsored by the National Institute on Drug Abuse (NIDA), The French Ministry of Health, the French National Institute for Health and Research (INSERM), and the International Medical Council on Drug Use. Organizers of the symposium were Gabriel G. Nahas (Columbia University), W. D. M. Paton (Department of Pharmacology, Oxford University), and Monique Braude (NIDA). Analysis, metabolism, cellular responses, and effects on reproduction and on the brain were the topics discussed during the two-day meeting. <h3>Pharmacokinetics</h3> The pharmacokinetics (absorption, distribution, biotransformation, and elimination) of the psychoactive substance of marijuana—Δ<sup>9</sup>-tetrahydrocannabinol, or THC—and of its byproducts (metabolites) were described by E. R. Garrett (University of Florida). Unlike water-soluble
Opiate withdrawal using clonidine. A safe, effective, and rapid nonopiate treatment
Authors: M. S. Gold
Journal: JAMA (1980)

Clonidine hydrochloride was administered to ten patients in an inpatient setting after abrupt discontinuation of chronic methadone hydrochloride administration. Clonidine produced a rapid and statistically significant decrease in opiate withdrawal signs and symptoms. Clonidine administration for 14 days enabled all patients to be successfully detoxified from chronic opiate administration. In all patients studied, clonidine was a safe and effective nonopiate treatment of opiate withdrawal that suppressed the affect, signs, and symptoms of opiate withdrawal. These data support the hypothesis that the α<sub>2</sub>-adrenergic agonist, clonidine, has substantial antiwithdrawal effect by replacing opiate-mediated inhibition with α2-mediated inhibition of brain noradrenergic activity. (<i>JAMA</i>243:343-346, 1980)
Acute Liver Injury by Vinyl Chloride: Involvement of Endoplasmic Reticulum in Phenobarbital-Pretreated Rats
Authors: Edward S. Reynolds, Rudolph J. Jaeger, Sheldon D. Murphy
Journal: Environmental Health Perspectives (1975)

A single 6-hr exposure to vinyl chloride monomer (5%) produces extensive vacuolization of centrolobular liver parenchyma and focal midzonal necrosis in the hepatic lobuole in phenobarbital-pretreated rats. Ultrastructurally, vacuolization consists of dilation of cysternae of rough endoplasmic reticulum and in the same cells smooth endoplasmic reticulum coalesces into discreet aggregates resembling denatured membranes. The findings support the hypothesis that vinyl chloride is hepatotoxic because it is converted into a toxic metabolite by components of the mixed function oxidase system of liver endoplasmic reticulum.
The New Crisis of Confidence in Psychiatric Diagnosis
Authors: Markus Donix
Journal: Annals of Internal Medicine (2013)

Letters19 November 2013The New Crisis of Confidence in Psychiatric DiagnosisMarkus Donix, MDMarkus Donix, MDFrom University Hospital Carl Gustav Carus, Dresden, Germany.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-159-10-201311190-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Frances (1) is correct that changes in diagnostic systems can lead to overdiagnosis and everyday life problems could be misclassified as illnesses. Physicians and patients do not like diagnostic uncertainty, the possibility of inaccurate diagnoses, and unnecessary or harmful "treatment." We also know how the media can echo these sentiments. Readers should consider several aspects.Revising a diagnostic manual is not unique to psychiatry. The definition of and treatment recommendations for various diseases, such as hypertension, have been adjusted numerous times. Recent discussion on obesity shows that even having a biological measure does not always allow for ...References1. Frances A. The new crisis of confidence in psychiatric diagnosis. Ann Intern Med. 2013;159:221-2. [PMID: 23685989] LinkGoogle Scholar2. Ahima RS, Lazar MA. Physiology. The health risk of obesity—better metrics imperative. Science. 2013;341:856-8. [PMID: 23970691] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Markus Donix, MDAffiliations: From University Hospital Carl Gustav Carus, Dresden, Germany.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe New Crisis of Confidence in Psychiatric Diagnosis Allen Frances The New Crisis of Confidence in Psychiatric Diagnosis Allen Frances Metrics Cited byVulnerability as practice in diagnosing multiple conditions 19 November 2013Volume 159, Issue 10Page: 720KeywordsAgingBrainConflicts of interestDementiaDiagnostic and Statistical Manual of Mental Disorders fifth editionDrugsHealth care providersHypertensionMemoryObesity ePublished: 19 November 2013 Issue Published: 19 November 2013 Copyright & PermissionsCopyright © 2013 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Pubertad: Diario de una colegiala
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Table of Contents
Authors: S Dhami, U Nurmatov, S Arasi, T Khan, M Asaria, H Zaman, A Agarwal, G Netuveli, G Roberts, O Pfaar, A Muraro, I Ansotegui, M Calderon, C Cingi, S Durham, R Gerth Van Wijk, S Halken, E Hamelmann, P Hellings, L Jacobsen, E Knol, D Larenas-Linnemann, S Lin, P Maggina, R Mösges, H Oude Elberink, G Pajno, R Pawankar, E Pastorello, M Penagos, C Pitsios, G Ro Ro, F Timmermans, O Tsilochristou, E.-M Varga, C Schmidt-Weber, J Wilkinson, A Williams, M Worm, L Zhang, A Sheikh, A Carsin, T Romain, S Ranque, M Reynaud-Gaubert, J.-C Dubus, J.-L Mège, J Vi, I Pali-Schöll, M De Lucia, H Jackson, J Janda, R Mueller, E Jensen-Jarolim, L Klimek, I Agache, C Akdis, C Bachert, J Bousquet, P Demoly, P Gevaert, V Hox, C Hupin, L Kalogjera, F Manole, J Mullol, N Muluk, N Papadopoulos, C Rondon, M Rundenko, S Seys, E Toskala, L Van Gerven, N Zhang, W Fokkens, D Smiljkovic, K Bla, G Stefanzl, Y Dorofeeva, C Skrabs, M Focke-Tejkl, W Sperr, U Jaeger, R Valenta, P Valent, J Caubet, J Lin, B Ahrens, G Gimenez, L Bardina, B Niggemann, H Sampson, K Beyer, S Koch, T Stroisch, J Vorac, N Herrmann, N Leib, S Schnautz, H Kirins, I Förster, H Weighardt, T Bieber, V Kopfnagel, S Wagenknecht, L Brand, J Zeitvogel, J Harder, K Hofmann, M Kleine, T Werfel, J.-M Xue, L.-T Yang, G Yang, X.-R Geng, Z.-Q Liu, S Wang, H.-L Zhao, Z.-G Liu, C.-Q Zhao, P.-C Yang, J.-F Stalder, H Aubert, E Anthoine, M Futamura, D Marcoux, M.-A Morren, M Trzeciak, Z Szalai, K Veres, M Deleuran, C Vestergaard, F Boralevi, C.-Y Chu, L De Raeve, Å Svensson, R Fölster-Holst, M Buchner, R Takaoka, V Aoki, P Chernyshov, L Chernyshova, D Murrell, C Mckinster, L Kobyletzky, L Eichenfi Eld, C Totri, P Lio, J Seneschal, L Moret, S Barbarot, T Fujimura, T Aki, T Isobe, A Matsuoka, T Hayashi, K Ono, S Kawamoto, T Kristensen, H Vestergaard, C Bindslev-Jensen, C Mortz, H Kjaer, M Ollert, M Møller, S Broesby-Olsen, N Rodriguez-Perez, E Schiavi, R Frei, R Ferstl, P Wawrzyniak, S Smolinska, M Sokolowska, N Sievi, M Kohler, P Schmid-Grendelmeier, D Michalovich, K Simpson, E Hessel, M Jutel, M Mar N-Fontecha, O Palomares, L O'mahony, A James, C Janson, A Malinovschi, C Holweg, K Alving, J Ono, S Ohta, A Ek, R Middelveld, B Dahlén, B Forsberg, K Izuhara, S.-E Dahlén, P Ntontsi, S Loukides, P Bakakos, K Kos, G Papatheodorou, E Papathanassiou, G Hillas, N Koulouris, S Papiris, A Papaioannou, L Overgaard, K Main, H Frederiksen, S Stender, P Szecsi, H Williams, J Thyssen, A Giménez-Arnau, L Curto-Barredo, L Nonell, E Puigdecanet, J Yelamos, R Gimeno, S Rüberg, L Santamaria-Babi, R Pujol, S Toppila-Salmi, A Luukkainen, R Lemmetyinen, J Karjalainen, H Huhtala, R Renkonen, D Wang, M Mäkelä, J Pekkanen, K Hasegawa, J Mansbach, N Ajami, J Petrosino, R Freishtat, S Teach, P Piedra, C Camargo, M Wi, M Nassiri, W Francuzik, K Lehmann, M Babina, Y Shahali, J.-P Sutra, C Hilger, K Swiontek, I Haddad, J Vinh, L Guilloux, D Charpin, H Sénéchal, P Poncet, M Ketelaar, K Van De Kant, F Dijk, E Klaassen, N Grotenboer, M Nawijn, E Dompeling, G Koppelman, B Remington, J Westerhout, D Campbell, P Turner
Journal: Allergy (2017)
CAUSE OF LAMP EXPLOSIONS.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Checklists for analyzing a community's emergency medical services
Authors: J. K. Owen
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Developmental Med &amp;amp; Child Neurology, London
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
JAAD Case Reports Article List
Authors: Heather Schopper, Nicholas Bontumasi, Mohammed Milhem, Karolyn Wanat, Swapna Reddy, Jayson Baman, Clinton Morrison, Glynis Scott, Vijay Krishna, Nisha Parmar, Satyaki Ganguly, Sheela Kuruvila, Divya Khosla, Roberto Novoa, Miesha Merati, Kord Honda, Meg Gerstenblith, Heather Holahan, Ronda Farah, Nkanyezi Ferguson, Amy Paller, Allison Legler, Romidepsin-Induced Neutrophilic Urticaria, Brian Scott, Heather Wickless, Kathleen Suozzi, Maximilian Stahl, Christine Ko, Anne Chiang, Scott Gettinger, Mark Siegel, Christopher Bunick, Amy Kalowitz Bieber, David Cohen, Jennifer Stein, Charlene Oldfield, Linda Heffernan-Stroud, Tara Buehler-Bota, Judith Williams, Joy Wan, Evan Piette, Misha Rosenbach, Jameson Loyal, Michael Romano, Joseph Pierson
Journal: Journal of the American Academy of Dermatology (2016)
The Young Physician.
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Poisoning from ingestion of asthma "powders"
Authors: M. Koff
Journal: JAMA (1966)

<h3>To the Editor:—</h3> The article "Postural Augmentation of Plasma Renin Activity" by Cohen, Rovner, and Conn (<b>197</b>:973, 1966) is an important exposition of the relationship of postural changes to the vagaries of renovascular hypertension. Their work would support our observations and those of other workers who have related changes occurring in the upright position to the production or exacerbation of hypertension of renal origin (<i>JAMA</i><b>187</b>:977, 1964). In this article and another on the subject (<i>Surgery</i><b>53</b>: 736, 1963) we have emphasized the association of renal ptosis to diminished renal blood flow both in the presence of stenosing lesions of the renal artery and in subjects whose vessels are otherwise normal. Some patients who have fibromuscular dysplasia of the renal artery may be normotensive in the recumbent position and hypertensive in upright postures. We have postulated that when the patient assumed an upright position, the kidney descended and
THE WAR AND MEDICAL EDUCATION. II
Authors: W. H. B.
Journal: Annals of Internal Medicine (1943)

Editorial1 December 1943THE WAR AND MEDICAL EDUCATION. IIW. H. B.W. H. B.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-19-6-1035 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptOne year ago this column1 was devoted to a discussion of the various problems in medical education that had arisen as a result of the war. At that time, the majority of medical schools in this country had already adopted an accelerated program with the admission of a new class every nine months and continuous instruction the year around, thus making it possible for the medical student to obtain the degree of Doctor of Medicine in three calendar years.As potential disadvantages of this accelerated program, it was pointed out that the students—not to mention the depleted and overworked faculties—might...1 The war and medical education, Editorial, ANN. INT. MED., 1942, xvii, 874-876. Google Scholar2 Plan for the allocation of interns and residents in hospitals, 1944, Jr. Am. Med. Assoc., 1943, cxxiii, 98. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 December 1943Volume 19, Issue 6Page: 1035-1038KeywordsMedical education Issue Published: 1 December 1943 PDF downloadLoading ...
Acute lung injury following lung resection: is one lung an-aesthesia to blame?
Authors: Mark Slade, Keith Burgess
Journal: Thorax (1996)

Lung disease induced by drug addictionIn their editorial on the pulmonary con- sequences ofillicit drug use (November 1995; 50:1125-7) Benson and Bentley draw at- tention to barotrauma as a complication of cocaine inhalation.Pneumothorax, pneumomediastinum, and pneumopericardium have also been described, however, in association with the use of marijuana,12 a drug that is more widely used in England and Australia than cocaine.The mechanism of injury is thought to be by coughing while breath- holding in inspiration, or by performance of a Valsalva manoeuvre.The latter has been recognised as a cause of spontaneous pneumo- mediastinum since the 17th century.3We have found it rewarding to seek a history of illicit drug use in young adult patients presenting with spontaneous pneumothorax.
Correction
Journal: Circulation (2005)

deleted. 2. On page 2063, in the footnotes to Table 3, footnote ‡ should read: "Milk listed is fat-free (except for children under the age of 2 years).If 1%, 2%, or whole-fat milk is substituted, this will utilize, for each cup, 19, 39, or 63 kcal of discretionary calories and add 2.6, 5.1, or 9.0 g of total fat, of which 1.3, 2.6, or 4.6 g are saturated fat." 3. On page 2063, in the footnotes to Table 3, footnote ¶ should read: "For 1-year-old children, calculations are based on 2% fat milk.If 2 cups of whole milk are substituted, 48 kcal of discretionary calories will be utilized.The American Academy of Pediatrics recommends that low-fat/reduced-fat milk not be started before 2 years of age." 4. On page 2064, in Figure 1, panel A represents females and panel B represents males.This information has been appended to the y-axis of each panel.5. On page 2067, in the second full paragraph, the first sentence should read: "The period from weaning to consumption of a mature diet, from 4 to 6 months to Ϸ2 years of age, represents a radical shift in pattern of food consumption (Figure 2), 17,126,126a,129,130 but there has been very little research on the best methods to achieve optimal nutritional benefit during this transition."The third sentence should read, "Transition to other sources of nutrients should begin at 4 to 6 months of age to ensure sufficient micronutrients in the diet, but the best methods for accomplishing this task are essentially unknown. 15,
OTOLARYNGOLOGY
Authors: Francis I. Catlin
Journal: JAMA (1966)

<h3>Major Reference Works</h3> A new edition of a major reference work has just become available:<i>Diseases of the Ear, Nose and Throat</i>(edited by Scott-Brown, Ballantyne, and Groves, ed 2; 2 vols, Butterworth, 1965, $70). This is a comprehensive textbook, with recent revisions in physiology, endoscopy, and diseases of the ear. Revision of the general index and inclusion of a new symptom index will assist the advanced student as well as the general practitioner. This edition is highly recommended to the otolaryngologist, as it amply discusses the management and diagnosis of major problems in this field. A new major reference work in plastic surgery,<i>Reconstructive Plastic Surgery</i>(Converse, J.M. [ed.], 5 vols, Saunders, 1964, $30 per vol) discusses seven topics. The first three volumes—1, General Principles; 2 and 3, The Head and Neck —will be of special interest to those who perform plastic procedures of the head and neck. These