Do Lipid-Lowering Agents Provide a Greater Reduction in Cardiovascular Events among Patients with Diabetes?
Authors: Ned Calonge
Journal: Annals of Internal Medicine (2008)

Letters2 December 2008Do Lipid-Lowering Agents Provide a Greater Reduction in Cardiovascular Events among Patients with Diabetes?Ned Calonge, MD, MPH and Diana Petitti, MD, MPHNed Calonge, MD, MPHFrom the Colorado Department of Public Health and Environment, Denver, CO 80246, and Keck School of Medicine, University of Southern California, Los Angeles, CA 90089.Search for more papers by this author and Diana Petitti, MD, MPHFrom the Colorado Department of Public Health and Environment, Denver, CO 80246, and Keck School of Medicine, University of Southern California, Los Angeles, CA 90089.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-149-11-200812020-00024 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:In making its recommendation on screening for type 2 diabetes, the USPSTF considered interventions, including lipid-lowering agents, for effects on such health outcomes as cardiovascular events. In reviewing the evidence on lipid-lowering agents, the USPSTF found that persons with diabetes do not seem to benefit to a greater extent than those without for the primary prevention of cardiovascular events, whether considering absolute or relative risk reduction. For example, in the Heart Protection Study, the absolute reduction in coronary events for participants receiving simvastatin versus placebo was similar in those with and without diabetes: 3.2% and 3.0%, respectively (calculated ...References1. Collins R, Armitage J, Parish S, Sleigh P, Peto R; Heart Protection Study Collaborative Group. MRC/BHF Heart Protection Study of cholesterol-lowering with simvastatin in 5963 people with diabetes: a randomised placebo-controlled trial. Lancet. 2003;361:2005-16. [PMID: 12814710] CrossrefMedlineGoogle Scholar2. Health Link, Medical College of Wisconsin. Calculate Your Risk of Coronary Heart Disease. Accessed at healthlink.mcw.edu/article/923521437.html on 21 October 2008. Google Scholar Author, Article, and Disclosure InformationAuthors: Ned Calonge, MD, MPH; Diana Petitti, MD, MPHAffiliations: From the Colorado Department of Public Health and Environment, Denver, CO 80246, and Keck School of Medicine, University of Southern California, Los Angeles, CA 90089.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoScreening for Type 2 Diabetes Mellitus in Adults: U.S. Preventive Services Task Force Recommendation StatementU.S. Preventive Services Task Force* Do Lipid-Lowering Agents Provide a Greater Reduction in Cardiovascular Events among Patients with Diabetes? Anil K. Gollapudi Metrics 2 December 2008Volume 149, Issue 11Page: 841-842KeywordsAspirinCardiovascular disease riskConflicts of interestDiabetes preventionHeartHypertensionLipidsLongitudinal studiesRelative riskType 2 diabetes ePublished: 2 December 2008 Issue Published: 2 December 2008 Copyright & PermissionsCopyright © 2008 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...