tbuckley/cabot-search huggingface dataset:
Postspinal Headache
Authors: William Cass
Journal: JAMA (1974)

Postspinal headache is not an uncommon complication of dural puncture. In 80% of cases, the headache resolves spontaneously within two weeks. Past treatment by empirical measures was not very successful. The epidural blood patch is a relatively new technique for treatment of postspinal headache. It has always been used within a few days of development of headache. In our patient the epidural blood patch was used successfully 11 weeks after the development of headache.
Echocardiographic predictors of abdominal aortic aneurysm: The cardiovascular health study Jonathan F. Plehn, Ellen O'Meara, Anne B. Newman, Joseph Polak, Teri A. Manolio, John S. Gottdiener. St. Francis Hospital, Roslyn, NY, National Heart, Lung and Blood Institute, Bethesda, MD
Journal: Journal of the American College of Cardiology (2001)
TREATMENT OF AMINO ACID DISORDERS
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Testing for Celiac Disease in Patients With Symptoms of Irritable Bowel Syndrome—Reply
Authors: Alexander C. Ford
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Painful questions about fibromyalgia
Journal: JAMA (1987)

<h3>To the Editor.—</h3> It was surprising to see an editorial<sup>1</sup>and review article<sup>2</sup>on "fibromyalgia" in a prestigious journal such as<i>JAMA</i>, but perhaps some discussion is better than none. It is not simply "contemporary medical prejudices" that keep many physicians from using the diagnosis of fibromyalgia. There simply has never been good evidence for it as a syndrome distinct from affective disorders. As Dr Goldenberg admits in his article, it "cannot be explained on current pathophysiologic grounds and lacks specific laboratory or other diagnostic tests." It is argued by Dr Bennett that "tender points" are an "objective abnormality" and by Dr Goldenberg that they constitute the "gold standard for diagnosis." Reference is made by the latter to the "dolorimeter," as if this quasiscientific device supports the existence of anything other than plain old aches and pains. Any medical student knows that using a stethoscope does not take
Marfan Syndrome
Authors: Reed E. Pyeritz
Journal: New England Journal of Medicine (1990)

Since nearly a century ago when the first professor of pediatrics in Paris, Antoine Marfan, described a young girl with long, spider-like fingers and other curious skeletal anomalies, understanding of the syndrome that now bears his name has expanded at an accelerating pace. There have been four distinct phases in the evolution of our knowledge, some of which are still in progress. The goal of the first phase, still incomplete, is a description of the phenotype. The cardinal ocular manifestation, ectopia lentis, was not recognized as being associated with the skeletal changes for two decades. The cardiovascular system was found . . .
Nano LC- mass spectrometry based proteomic profiling associated with significant fibrosis and collagen deposition in non-alcoholic fatty liver disease (NAFLD)
Authors: Z.M. Younossi, A. Karrar, M. Pierobon, Z. Younoszai, S. Felix, T. Jeffers, M. Stepanova, K. Jeiran, A. Hodge, F. Monge, L. Alaparthi, D. Abdelatif, A. Birerdinc, V. Chandhoke, Z. Goodman, E. Petricoin
Journal: Journal of Hepatology (2017)
Medicine in the Far East.
Authors: M. S. Caldwell
Journal: JAMA (1900)

Vienna, Austria, April 13, 1900. LUCKNOW. <h3>To the Editor:</h3> I found rather "short picking" as far as medicine is concerned, in Lucknow. There is a special hospital there for lying-in and gynecologic cases, but as everywhere in India women have a deep-rooted prejudice against allowing men to examine or treat them; they are very generally cared for by an inexperienced female. By a visit to King's Hospital. I made the acquaintance of Dr. Raham Khan Bahadur, a native physician of wide reputation, and especially noted as an operator for cataract. The Doctor has done over 7000 operations of this kind, after a manner that he claims is practiced only by himself. He uses pure cocain in powder, to render the eye insensible. He makes the usual incision before his extraction, but uses no eye speculum, and does not fix the eye with forceps while operating. After the incision is made,
Reply
Authors: J P Galmiche, C Scarpignato, S B. D. Varannes, G Shi
Journal: Gut (1996)

Letters, Note representative and even more to establish hypersensitivity to acid.Thus, these several difficulties in pH monitoring in a hetero- genous patient group do, in our opinion, prevent a new classification of oesophageal hypersensitivity to acid.A prospective and standardised study in these patients is needed to better define whether the hypersensitive oesophagus is a distinct clinical entity, or whether pH monitoring underdiagnoses gastro-oesophageal reflux disease.
The Transmission of Yellow Fever.
Authors: James Carroll
Journal: JAMA (1903)

<h3>A REPLY TO DR. AGRAMONTE.</h3> Washington, D. C., June 26, 1903. <i>To the Editor:</i>—In connection with my paper published inThe Journalof May 23 several statements made by my esteemed colleague, Dr. Aristides Agramonte, in his letter published in theJournalof June 13, call for reply, and I beg to be permitted to submit the following necessary explanations: With manifest feeling Dr. Agramonte takes exception to the omission of his name in the early part of my paper—and naturally too, in view of his lack of knowledge of the facts—and proceeds to show that I was in error in my statement that the decision to put the mosquito theory to a practical test was arrived at during a consultation between Drs. Reed, Lazear and myself. He then makes certain statements in regard to our late colleague, Dr. Lazear, with which, with one exception, I heartily agree, and
A Country Doctor
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cardiorespiratory responses to aerobic training by patients with postpoliomyelitis sequelae
Authors: D. R. Jones
Journal: JAMA (1989)

We examined the cardiorespiratory responses of 16 patients with postpoliomyelitis sequelae to a 16-week aerobic exercise program. The patients exercised at 70% of maximal heart rate. Dependent variables were resting and maximal heart rates, systolic and diastolic blood pressures, maximum oxygen consumption, maximum carbon dioxide consumption, respiratory quotient, and maximum expired volume per unit time. The exercise group was superior to the control group in watts, exercise time, maximum expired volume per unit time, and maximum oxygen consumption. No untoward events or loss of leg strength occurred as a result of the exercise regimen. We conclude that the aerobic training program employed in this study is a safe, short-term procedure and that patients with postpolio sequelae respond to training in a manner similar to healthy adults. (<i>JAMA</i>. 1989;261:3255-3258)
Synthetic Marijuana Sends Hundreds for Emergency Care in Colorado
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Overview of Preventable Industrial Causes of Occupational Cancer
Authors: Elizabeth Ward
Journal: Environmental Health Perspectives (1995)

This paper summarizes what is known about preventable causes of occupational cancer, including single agents, complex mixtures, and broad occupational associations.Epidemiologic methods have been very successful in documenting cancer risks associated with single agents.Epidemiologic data are most conclusive when an exposure-response relationship can be demonstrated.Examples of agents for which epidemiologic studies provide evidence of an exposure-response relationship include benzene and (concurrent exposure to) ortho-toluidine and aniline.Vinyl chloride and bischloromethyl ether are examples of associations between single agents and rare histologic types of cancer.It is more difficult to conduct epidemiologic studies to identify cancer risks associated with complex mixtures.Studies of diesel exhaust and lung cancer and metal machining oils are cited as having employed advanced industrial hygiene and epidemiologic methods for studies of complex mixtures.Elevated cancer risks have also been identified in broad occupational groups, including painters and dry cleaners.Epidemiologic case-control studies are often used to detect such associations but are limited in their abilities to detect the causal agents.Major gaps exist in knowledge of occupational cancer risks .amongwomen workers and workers of color.Because epidemiologic research measures illness and mortality that have already occurred, a positive study can be interpreted to represent a failure in prevention.The challenge we face in the next decade is to identify interventions earlier in the causal pathway (toxicologic testing, biomarkers of exposure or precancerous changes, institution of engineering and good industrial hygiene practices to reduce occupational exposure levels) so that occupational cancer can be prevented.
REPLANTATION CONSIDERED
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contempo '81. Physical medicine and rehabilitation
Authors: E. W. Johnson
Journal: JAMA (1981)

The United Nations has proclaimed 1981 the International Year of the Disabled, and thus the research and clinical advances in physical medicine and rehabilitation are appropriately highlighted. <h3>Diagnosis</h3> Single-fiber electromyography has emerged as a clinically useful technique to identify neuromuscular transmission defects at an earlier stage in myasthenia gravis and related diseases. It also has become helpful in the semiquantitative estimation of reinnervation after nerve regrowth and certain motor unit diseases. This technique involves the measurement of variations in latencies of transmission of clinically mediated nerve impulses across the myoneural junction within a given motor neuron. Somatosensory potentials recorded over the head and spinal cord have been useful procedures to evaluate afferent pathways in the CNS. These may have prognostic value early in the course of head and spinal cord injuries and are also being used to monitor the spinal cord in certain operations on the spinal column. <h3>Pain Management</h3>
Evaluation of potentially preventable deaths among pedestrian and bicyclist fatalities
Authors: F. P. Rivara
Journal: JAMA (1989)

The prehospital, emergency department, and in-hospital care of 84 patients who died following a pedestrain— or bicycle—motor vehicle collision in a four-county area was retrospectively reviewed using a systematic, detailed scoring system. The purpose of the study was to examine the effectiveness of an advanced paramedic—regionalized trauma care system and to examine the usefulness of a systematic evaluation tool in identifying preventable and possibly preventable deaths. Among the 84 deaths, one was judged to be preventable and 18 possibly preventable. The one preventable death occurred in the emergency department, while the possibly preventable deaths more commonly occurred after 48 hours and were due to central nervous system injury, sepsis, and multiple organ failure. Prolonged prehospital and emergency department time and failure to establish an airway were the most common problems identified as contributing to fatal outcome. The use of explicit criteria was demonstrated to be an effective addition to the analysis of trauma care systems. (<i>JAMA</i>1989;261:566-570)
Update: Influenza Activity and Vaccine Availability—United States, 1991 and 1992
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ERRATUM
Journal: Journal of Clinical Oncology (2008)

In the Results section, under Accrual by Age Group, the second sentence indicated that 80.7% of patients were accrued onto trials, whereas it should have been 37.9% as follows:"Overall, 37.9% of Maryland pediatric and adolescent incident patients with cancer were accrued onto treatment trials."In Table 3, under % Patients Accrued by Sex Within Race/Ethnic Group, 60.1% was given for White females, whereas it should have been 60.7%.The online version has been corrected in departure from the print.
AN ADVENTURE IN ATROPISM
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Durable remissions from fludarabine followed by the iodine I-131 tositumomab Bexxar therapeutic regimen for patients with previously untreated follicular non-Hodgkin's lymphoma (NHL)
Authors: J. P. Leonard, M. Coleman, L. Kostakoglu, A. Chadburn, J. M. Fiore, R. R. Furman, M. W. Schuster, S. M. Kroll, S. J. Goldsmith
Journal: Journal of Clinical Oncology (2004)

6518 Background: The sequential combination of chemotherapy and radioimmunotherapy offers a novel strategy for the initial management of NHL. Tositumomab and iodine I 131 tositumomab (Bexxar) have been demonstrated to have substantial clinical activity in both untreated and relapsed/refractory low-grade NHL. Fludarabine synergizes in vitro with unlabeled and radiolabeled antibodies and can be employed as a "debulking" agent prior to radioimmunotherapy. Methods: Patients with previously untreated, advanced low-grade NHL were treated with IV fludarabine 25 mg/m2/day for 5 days, every 5 wks for 3 cycles followed in 6 to 8 wks by Bexxar therapy. Results: Between August 1998 and June 1999, 38 pts (51% follicular mixed, 49% follicular small cleaved) were enrolled and 97% had stage III/IV disease. Thirty-five subjects received both fludarabine and Bexxar therapy. Three patients came off study before or during fludarabine therapy (one due to cytopenias, 2 unrelated to toxicity or lymphoma progression). Response to fludarabine (n=35) was 89% (3 CR, 28 PR). Following Bexxar therapy, 35 of 35 subjects (100%) had a response including 83% CR. With a median follow-up of 4.4 years, median progression-free survival has not been reached, and 72% of pts achieving a CR remain in CR. Among 35 evaluable pts, grade 4 neutropenia, thrombocytopenia, and anemia were noted in 34%, 29%, and 3% of pts, respectively. Sixteen (46%) pts received growth factor or transfusion support. There were no serious infections. Four (12%) pts developed elevated TSH and 2 (6%) pts developed HAMA. No pts have developed MDS/AML. Conclusions: Fludarabine followed by Bexxar therapy appears to be a highly effective and well tolerated regimen for the initial therapy of advanced follicular NHL, producing long-term durable complete remissions in the majority of patients. Author Disclosure Employment or Leadership Consultant or Advisory Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration Corixa Corp. Corixa Corp. Corixa Corp. Corixa Corp. Corixa Corp.
Mining Social Media Data to Assess the Risk of Skin and Soft Tissue Infections from Allergen Immunotherapy
Authors: Aidan A. Long, Maxim Topaz, Li Zhou, Tyler Harkness, Mariah Ollive, Roee Sa'adon, Ofrit Bar-Bachar, Kimberly G. Blumenthal
Journal: Journal of Allergy and Clinical Immunology (2019)
The chemistry of the immunoglobulins
Authors: H. Metzger
Journal: JAMA (1967)

The immunoglobulins are the most complex system of proteins known. They have no peers with respect to the structural diversity which they exhibit or with respect to the sophisticated mechanisms which must regulate their synthesis. On the other hand, there are few proteins which have been as thoroughly studied and about which there exists such a large body of information regarding structure, synthesis, catabolism, and function. Several detailed reviews of immunoglobulin chemistry have recently appeared<sup>1,2</sup>and several are in press.<sup>3,4</sup>In this paper, I will try to outline present concepts in a more general way. I have tried to organize the material in a logical framework so that the various levels of organization of the immunoglobulin system are highlighted. <h3>The Structure of Immunoglobulins</h3> There are three aspects of immunoglobulin structure which must be understood: All immunoglobulins have a common fundamental structure. Superimposed on this common subunit