tbuckley/cabot-search huggingface dataset:
Increasing Ciprofloxacin Resistance Among US Shigellosis Outbreaks
Journal: JAMA (2015)

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Public Health Doctors' Conference
Journal: BMJ (1966)

three had grand mal attacks.More recently L. A. Swanson and T. Okada' reported the death of a 38-year-old man from cardiovascular collapse after withdrawal of mepro- bamate, of which he had previously taken up to 10 g. daily.The symptoms of the syndromes of abstinence from barbiturates or meprobamate have much in common with each other and with alcoholic delirium tremens.An initial period of up to 12 hours without symptoms after withdrawal of the drug may mislead the unwary clinician.Thereafter anxiety, insomnia, sweating, vomiting, and tremor develop, followed in severe cases by confusion, fever, hallucinations, epileptic convulsions, and hypotensive heart failure.The convulsions may fail to respond to normal doses of anticonvulsants.I. C. Wilson8 described a patient with status epilepticus after withdrawal of meprobamate and benactyzine, in whom fits were stopped only by restoration of the previous medication, other anti-epileptic measures having failed.Haizlip and
Angina of Micturition
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cryptic pulmonary lesions in workers occupationally exposed to dust containing silica
Authors: J. E. Craighead
Journal: JAMA (1980)

Fibrotic lesions associated with deposits of crystalline silica were found postmortem in the lungs of 15 granite workers who lacked radiological evidence of pneumoconiosis. All members of this occupational group had been employed in the granite quarrying and monument industry of Vermont since ambient air-dust standards were introduced in 1937. Although particulate silica was not revealed in the lesions by traditional polarization light microscopy, it was identified by scanning electron microscopy in conjunction with backscatter imaging and x-ray spectrometry. The etiologic basis of the fibrotic pulmonary disease would not have been diagnosed without the aid of these modern analytical tools. Exposure to silica-containing dust can result in cryptic pulmonary disease that is not detectable radiologically. In these retrospective postmortem studies, it was not possible to define the distribution of the lesions in the lungs. (<i>JAMA</i>244:1939-1941, 1980)
Ontario Medical Association.
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Octreotide
Authors: Steven W.J. Lamberts, Aart-Jan van der Lely, Wouter W. de Herder, Leo J. Hofland
Journal: New England Journal of Medicine (1996)

A peptide inhibiting the release of growth hormone was originally detected accidentally during studies of the distribution of growth hormone–releasing factor in the hypothalamus of rats.1 This peptide, called somatostatin, proved to be a cyclic peptide consisting of 14 amino acids.2 Subsequent work has considerably expanded this initially simple concept of somatostatin as a peptide whose main function is the regulation of growth hormone secretion.3 Today, somatostatin is best regarded as a phylogenetically ancient, multigene family of peptides with two important bioactive products: somatostatin-14 and somatostatin-28, the latter a congener of somatostatin-14 extended at the N-terminal.3,4 Like other peptide . . .
Journal Amer Dietetic Association, Chicago
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Figure Upside-Down
Journal: JAMA (1965)

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Trapped nerves.
Authors: R H Maudsley, N C Roles
Journal: BMJ (1972)

your article, were treated by radium only, and there seems little doubt that the high uterine dose necessary for a radium meno- pause is more likely to lead to later malig- nancy than the lower dose given by external irradiation.The indications for inducing a radiation menopause are few; for a radium menopause there are none.-I am, etc.,
A NATIONAL DEPARTMENT OF HEALTH
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Incorrect Spelling of Author Name, Incorrect Affiliation of Another Author, and Removal of Academic Degree
Authors: David Brent, Giovanna Porta
Journal: JAMA (2019)

The Consortium on Thyroid and Pregnancy—Study Group on Preterm Birth; Tim I. M. Korevaar, MD, PhD; Arash Derakhshan, MD, MSc; Peter N. Taylor, MRCP, PhD; Marcel Meima, PhD; Liangmiao Chen, MD, PhD; Sofie Bliddal, MD; David M. Carty, MD; Margreet Meems, MD, PhD; Bijay Vaidya, FRCP, PhD; Beverley Shields, PhD; Farkhanda Ghafoor, PhD; Polina V. Popova, MD, PhD; Lorena Mosso, MD, PhD; Emily Oken, MD, MPH; Eila Suvanto, MD, PhD; Aya Hisada, PhD; Jun Yoshinaga, PhD; Suzanne J. Brown; Judit Bassols, MD; Juha Auvinen, MD, PhD; Wichor M. Bramer; Abel López-Bermejo, MD, PhD; Colin Dayan, MD, PhD; Laura Boucai, MD, MSc; Marina Vafeiadi, PhD; Elena N. Grineva, MD, PhD; Alexandra S. Tkachuck, MD; Victor J. M. Pop, MD, PhD; Tanja G. Vrijkotte, PhD; Mònica Guxens, MD, PhD; Leda Chatzi, MD, PhD; Jordi Sunyer, MD, PhD; Ana Jiménez-Zabala, PhD; Isolina Riaño, MD, PhD; Mario Murcia, PhD; Xuemian Lu, MD, PhD; Shafqat Mukhtar, MD; Christian Delles, MD; Ulla Feldt-Rasmussen, MD, DMSc; Scott M. Nelson, MRCOG, PhD; Erik K. Alexander, MD; Layal Chaker, MD, PhD; Tuija Männistö, MD, PhD; John P. Walsh, MB, PhD; Elizabeth N. Pearce, MD; Eric A. P. Steegers, MD, PhD; Robin P. Peeters, MD, PhD
Correction of a Table Column Heading
Authors: Christy Chai, Hop Cao, Nader Massarweh, Michael Debakey, Tran Chai, Tran Cao, Rakesh Joshi, Dhirendra Shrivastava, Jaishri Ramji, Mch Finally
Journal: JAMA Surgery (2018)

Alexander Egeberg, MD, PhD; Jens Ahm Sørensen, MD, PhD; Gunnar Hilmar Gislason, MD, PhD; Filip Krag Knop, MD, PhD; Lone Skov, MD, PhD, DMSc
Epidemiology of minimal breast cancer
Authors: L. A. Brinton
Journal: JAMA (1983)

A case-control study conducted within the Breast Cancer Detection Demonstration Project allowed comparison of epidemiologic factors for benign breast diseases (n=1,404), in situ cancer (n=199), small (≤1 cm) invasive cancer (n=210), and larger invasive cancer (n=788). Control subjects consisted of program participants who were not recommended for breast biopsy. Relationships were similar for small and larger invasive tumors, both showing associations with family history of breast cancer, age at first live birth, history of bilateral oophorectomy, and obesity. In situ cancer was affected by family history and age at first childbirth but not by oophorectomy or obesity. These findings support the notion that "minimal" breast cancer is indeed cancer. In addition, the results suggest that hormonal influences early in life may initiate the carcinogenic process, while those that operate later may enhance the progression from in situ to invasive disease. (<i>JAMA</i>1983;249:483-487)
Legtures to Students on Diphtheria, Measles, Scarlatina.
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Aids to Obstetrics
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TENDON SUBSTITUTION TO RESTORE FUNCTION OF THE EXTENSOR MUSCLES OF THE FINGERS AND THUMB
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A TREATMENT FOR COLIC IN BREAST-FED INFANTS
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction
Authors: C. D. Riffkin
Journal: Neuro-Oncology (2001)

Neuro-Oncology n O C T O B E R 2 0 0 1 229 Fas (APO-1/CD95/TNFRSF6) is a member of the tumor necrosis/nerve growth factor receptor family that signals apoptotic cell death in sensitive cells.Expression of Fas and its agonistic ligand (FasL/TNFSF6) was investigated in ex vivo pediatric brain tumor specimens of various histologic types.Fas expression was identi ed in all of the 18 tumors analyzed by ow cytometry and immunohistochemistry. FasL expression was identi ed in most of the 13 tumors analyzed by both Western analysis and immunohistochemistry. Nine of these tumor specimens were treated with either the agonistic anti-Fas antibody (APO-1) in combination with protein A or FasL in shortterm cytotoxicity assays.Sensitivity to apoptosis induced by the topoisomerase II inhibitor, etoposide, was also assessed.Despite the presence of Fas, all the specimens analyzed demonstrated a high degree of resistance to Fasmediated apoptosis.These 9 specimens also showed a high degree of resistance to etoposide.Only 2 of the 9 specimens were susceptible to etoposide-induced cell death, whereas only 3 were sensitive to Fas-mediated apoptosis.One brain tumor was sensitive to both Fas ligation and etoposide treatment.This contrasted with the high degree of susceptibility to both etoposide-and Fas-induced apoptosis observed in the reference Jurkat cell line.The results suggest that Fas expression may be a general feature of tumors of the CNS and that a signi cant degree of resistance to Fas-mediated apoptosis may exist in ex vivo pediatric brain tumor specimens.
Abstract 361: Inactivation of Cardiac Foxo1 by Insulin Signaling Is Required for Cardiac Function and Suppression of β-Myosin Heavy Chain Gene Expression
Authors: Yajuan Qi, Qinglei Zhu, Kebin Zhang, Candice Thomas, Rajesh Kumar, Kenneth M. Baker, Shaodong Guo
Journal: Circulation Research (2014)

Heart failure is a leading cause of morbidity and mortality in the USA and is closely associated with diabetes mellitus. The molecular link between diabetes and heart failure is incompletely understood. We recently demonstrated that insulin receptor substrate 1, 2 (IRS1, 2) are key components of insulin signaling and their dysfunction mediates insulin resistance, resulting in metabolic dysregulation and heart failure. Loss of IRS1 and IRS2 is associated with downstream Akt inactivation and in turn activation of the forkhead transcription factor Foxo1. To determine the role of Foxo1 in control of heart failure in insulin resistance and diabetes, we generated mice lacking Foxo1 gene specifically in the heart. Mice lacking both IRS1 and IRS2 in adult hearts exhibited severe heart failure, loss of mitochondria, and a remarkable increase in the β-isoform of myosin heavy chain (β-MHC) gene expression, while deletion of cardiac Foxo1 gene largely prevented the heart failure and the loss of mitochondria, and resulted in a decrease in β-MHC expression. The effect of Foxo1 deficiency on rescuing cardiac dysfunction was also observed in db/db mice and high-fat diet (HFD) mice. Using cultures of primary ventricular cardiomyocytes, we found that Foxo1 interacts with the promoter region of β-MHC and stimulates gene expression, mediating an effect of insulin that suppresses β-MHC expression. Taken together, our study suggests that Foxo1 has important roles in promoting diabetic cardiomyopathy and controls β-MHC expression in development of cardiac dysfunction. Targeting Foxo1 and its regulation will provide novel strategies in preventing metabolic and myocardial dysfunction and influencing MHC plasticity in diabetes mellitus.