tbuckley/cabot-search huggingface dataset:
ITALY
Journal: JAMA (1946)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Exhibit Wins Billings Gold Medal
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
<i>Illustrations of the Gross Morbid Anatomy of the Brain in the Insane. A Selection of Seventy-five Plates Showing the Pathological Conditions Found in Post-Mortem Examinations of the Brain in Mental Disease.</i>By I. M. Blackburn, M. D., Pathologist to the Government Hospital for the Insane, Washington, D. C., etc. (Washington: Government Printing Office, 1908.)
Journal: American Journal of Psychiatry (1909)
Northern overexposure.
Authors: D J Tenenbaum
Journal: Environmental Health Perspectives (1998)

The top of the world may look pristine, but the Arctic environment and its inhabitants contain surprisingly high levels of heavy metals, persistent organic pollutants such as pesticides, and nuclear radiation. Although the Arctic has few significant pollution sources, the contaminants are swept northward on ocean currents and winds from industrial regions. Once contaminants arrive, low temperatures and limited sunlight slow their decay, and bioaccumulation concentrates some of them to dangerous levels.
Elevated Levels of LDH, GOT, and Catalase in Infected Urine
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
High elevations of creatine phosphokinase in hypothyroidism. An isoenzyme analysis
Authors: J. Goldman
Journal: JAMA (1977)

In hypothyroidism, slight elevations of serum creatine phosphokinase (CPK) levels are common. In contrast, we describe six hypothyroid patients with extreme elevations (17- to 160-fold) of CPK levels. Enzyme analysis showed only MM isoenzyme in four cases and MM plus trace MB isoenzyme in two patients. Hypothyroidism should, therefore, be considered when elevated CPK levels, even if extreme, are found. Isoenzyme analysis in such a case will show primarily an MM pattern, although trace MB fraction can also be seen. This isoenzyme pattern suggests that the source of the CPK elevations is skeletal muscle. (<i>JAMA</i>238:325-326, 1977)
NATIONAL EXPANSION.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Measurement of DNA Repair Deficiency in Workers Exposed to Benzene
Authors: Lance M. Hallberg, Randa El Zein, Lawrence Grossman, William W. Au
Journal: Environmental Health Perspectives (1996)

We hypothesize that chronic exposure to environmental toxicants can induce genetic damage causing DNA repair deficiencies and leading to the postulated mutator phenotype of carcino- genesis.To test our hypothesis, a host cell reactivation (HCR) assay was used in which pCMVcat plasmids were damaged with UV light (175, 350 J/m2 UV light), inactivating the chloramphenicol acetyltransferase reporter gene, and then transfected into lymphocytes.Transfected lymphocytes were therefore challenged to repair the damaged plasmids, reactivating the reporter gene.Xeroderma pigmentosum (XP) and Gaucher cell lines were used as positive and negative controls for the HCR assay.The Gaucher cell line repaired normally but XP cell lines demonstrated lower repair activity.Additionally, the repair activity of the XP heterozygous cell line showed intermediate repair compared to the homozygous XP and Gaucher cells.We used HCR to measure the effects of benzene exposure on 12 exposed and 8 nonexposed workers from a local benzene plant.Plasmids 175 J/m2 and 350 J/m2 were repaired with a mean frequency of 66% and 58%, respectively, in control workers compared to 71 % and 62% in exposed workers.Conversely, more of the exposed workers were grouped into the reduced repair category than controls.These differences in repair capacity between exposed and control workers were, however, not statistically significant.The lack of significant differences between the exposed and control groups may be due to extremely low exposure to benzene (< 0.3 ppm), small population size, or a lack of benzene genotoxicity at these concentrations.These results are consistent with a parallel hprt gene mutation assay.
In treating the pathological gambler, MDs must overcome the attitude, 'Why bother?'
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contents
Authors: Vinay Kansal, Matthew Schlenker, Ike Ahmed, Thomas Oetting, Wei Zheng, Thaddeus Dryja, Zhongyuan Wei, Dongying Song, Haijun Tian, Kristijan Kahler, Anthony Khawaja, Eric Crowell, Laura Baker, Alice Chuang, Robert Feldman, Nicholas Bell, Patricia Chévez-Barrios, Lauren Blieden, Hae-Young Park, Jin Kim, Chan Park, Justis Ehlers, Yasha Modi, Paula Pecen, Jeff Goshe, William Dupps, Aleksandra Rachitskaya, Sumit Sharma, Alex Yuan, Rishi Singh, Peter Kaiser, Jamie Reese, Carmen Calabrise, Allison Watts, Sunil Srivastava, Markus Rohm, Volker Tresp, Michael Müller, Christoph Kern, Ilja Manakov, Maximilian Weiss, Dawn Sim, Siegfried Priglinger, Pearse Keane, Karsten Kortuem, Ebenezer Daniel, Wei Pan, Gui-Shuang Ying, Benjamin Kim, Juan Grunwald, Frederick Ferris, Glenn Jaffe, Cynthia Toth, Daniel Martin, Stuart Fine, Maureen Maguire
Journal: Ophthalmology (2018)
Abstract 54: Preliminary Results With The Use Of <i>Stat</i> · <i>Padz</i> Pacing Electrode For Treatment Of Symptomatic Bradycardia In Emergency Department.
Authors: Maria Margarita Gonzalez, Luis Augusto Dallan, Rogerio B Ramos, Evelinda Trindade, Sergio Timerman, Antonio P Mansur
Journal: Circulation (2007)

Background: Since the mid-1980’s transthoracic pacing has been a common temporary treatment for arrhythmias. Present external pacing technology requires the application of both multifunction defibrillation electrodes and separate leads for electrocardiogram (ECG) monitoring. Separate ECG leads are required as the current from the pacing pulse creates artifact in the signal that prevents one from distinguishing between pace-captured and non-captured rhythms when using the defibrillation electrode alone. Hypotheses: We hyothezised that Stat· padz MWP electrode, a transthoracic electrode that integrates the ECG electrodes into the defibrillation and pacing pad woud be abble to reconize captured and non-captured rhythms in a typical clinical setting of the syntomatic bradycardia. Methods: We conducted a prospective study at Emergency Department of a University Hospital. During October 2006 to April 2007, 28 patients with symptomatic bradycardia were include in the study. Comparison between monitoring by conventional electrode and Stat· padz MWP electrode was performed. After that was selected Lead II, and adjusted pacing rate and milliamps for the stimulation. Records and comparison of electrical capture was performed with the three lead conventional electrodes and Stat· padz MWP electrodes. Results: The mean electrocardiographic diagnoses was third degree atrio-ventricular block in 50% of patients, and the principal symptoms were presyncope in 82 %, symptoms of reduced cardiac output in 79% and syncope in 43%. Previous diagnoses were Hypertension in 57%, Chagas’s heart disease in 21%, Valvar heart disease in 14% and Dilated Cardiomyopathy in 18 %. Monitoring of cardiac rhythm, electrical and mechanical capture were obtained in 100 % of patients. The mean energy for capture was 69±18 milliamps. When compared the records of electrocardiographic capture with Stat· padz MWP electrode, it was equal than conventional electrodes in 46 % and better in 54 %. Conclusion: The Stat· padz MWP electrode has the feasibility of recognise capture and non-capture rhythms and to perform pacing function effectively. It presents the possibility of providing rapid treatment in patients with syntomatic bradycardia avoiding monitoring by conventional electrodes.
Active Immunization
Authors: Geoffrey Edsall
Journal: New England Journal of Medicine (1946)

InfluenzaFollowing the identification of a virus agent causing human influenza,314 efforts were made to develop vaccines effective in preventing or at least mitigating the infection. The finding of Burnet315 that the fertile hen's egg provided a favorable medium for cultivating the influenza virus led ultimately to the use of this agent as the preferred culture medium. The demonstration that at least two distinct types of virus — designated "A" and "B" — could cause influenza316 , 317 posed the necessity of producing an effective bivalent vaccine. Numerous studies, usually with monovalent preparations, gave more or less equivocal results, whether the vaccine . . .
Gastrointestinal bleeding
Authors: O. Le Moine, J. Devière
Journal: Endoscopy (2010)

Gastrointestinal bleeding is the most prevalent indication for performing unscheduled diagnostic, and if needed, therapeutic endoscopy. For decades, therapeutic endoscopy in these circumstances has decreased mortality and the need for surgery. Nowadays however, even in cases of effective hemostasis, the prognosis for patients is driven more by co-morbidities. Epidemiology, etiology, pathophysiology, and treatment of gastrointestinal bleeding have dramatically changed over the past decades, leaving many questions open, particularly regarding the multidisciplinary and transversal management of these patients. At this year’s Digestive Disease Week (DDW 2010, 1 – 5 May, New Orleans, Louisiana, USA), abstracts on gastrointestinal bleeding made up 9 % of the accepted abstracts (478/5232), underscoring the importance of this subject in routine practice. Here we discuss those abstracts that focused on human cases of gastrointestinal bleeding with important expected clinical impact.
Actinomycin and Its Effects
Authors: Larry D. Samuels
Journal: New England Journal of Medicine (1964)

(Concluded)*Inhibition of Hormone ActionAlthough an increasing body of clinical data has allowed the pharmacology of most hormones to be fairly well understood the specific metabolic mode of action of many hormones has not been known. With recent advances in biochemistry, the significant role of hormones in several important biochemical pathways has come to be appreciated. One major group of hormones has been linked with protein anabolism. Civin and Knox,98 reporting tryptophan pyrrolase induction by hydrocortisone, concluded that "hormones are primary inducers of enzymes." The mechanism of protein synthesis via mRNA was not understood at that time, but the . . .
Annual Reports
Authors: William H. Evans
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
An update on the usefulness of the intensity of <sup>18</sup>fluorodeoxyglucose uptake in positron emission tomography (FDG-PET) in distinguishing between indolent and aggressive non-Hodgkin’s lymphomas
Authors: J. Chalapud, P. Sobrevilla-Calvo, C. Cadena, G. Galvan, V. Lozano, S. Rivas-Vera
Journal: Journal of Clinical Oncology (2008)

8602 Background: FDG PET is recommended for the initial evaluation and staging of patients with non-Hodgkin’s lymphoma (NHL). There is not enough knowledge about the usefulness of PET in distinguishing different subtypes of NHL, so we investigated whether the intensity of tumor FDG uptake in NHL is different between indolent and aggressive histology. This comparison may also clarify the value ot an initial PET scan in indolent lymphoma, because of its lower and unpredictable uptake. Methods: We studied a retrospective cohort of lymphoma patients with NHL, attended at a single tertiary care center from April 2003 to November 2007 and who had not received treatment. We reviewed the initial, re-staging and/or relapse PET studies of 101 patients with diagnosis of NHL. Mean age 45 (15 to 86) years, 41 female and 60 male. We recorded the highest standardized uptake value (SUV), correlations were made with histopathology. We analyzed SUVs considering the various histologies and grades. Two sample comparisons were performed using the Wilcoxon test. Results: The histopathological diagnoses were: diffuse large B-cell lymphomas (53 patients), anaplastic large cell lymphoma (8 patients), Follicular lymphoma grade 1 and 2 (25 patients), Follicular lymphoma grade 3 (5), Burkitt (5), and other types (5 patients, 1 MALT, 1 lymphoma/CLL, 1 mycosis fungoides, 2 peripheral t cell lymphoma). FDG uptake was lower in indolent (29 patients) than aggressive lymphoma (72 patients) (SUV, mean 5.8, SD ± 2.2, mean rank 26.2, sum of ranks 768 vs 13.5 SD ± 6.9, mean rank 60.9, sum of ranks 4388; P=<.0001). Despite overlap between indolent and aggressive disease in the low SUV range (indolent 1.9 to 11; aggressive 3.2 to 33) all cases of indolent lymphoma had an SUV ≤ 11. Conclusions: These findings confirm our previous results showing that the FDG uptake is significantly lower in indolent than in aggressive lymphoma. Patients with NHL and SUV > 11 have a high likelihood for aggressive disease. These results also suggest that to follow the treatment response in indolent lymphoma is important to have an initial PET study. No significant financial relationships to disclose.
Software
Authors: T. Keith Edwards
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
NATIONAL DEPARTMENT OF HEALTH.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PS-174-Serum bile acid profiles distinguish severe alcoholic hepatitis from decompensated alcohol-related cirrhosis
Authors: Luke D. Tyson, Stephen Atkinson, Alexandros Pechlivanis, Elaine Holmes, Nikhil Vergis, Rooshi Nathwani, James Maurice, Simon Taylor-Robinson, Benjamin H. Mullish, Roger Williams, MarkJ W McPhail, Vishal Patel, Mark Thursz
Journal: Journal of Hepatology (2019)
A new view on one form of chronic hepatitis
Authors: G. A. Alt
Journal: JAMA (1982)

Researchers at the University of California, San Francisco (UCSF), have gathered evidence that challenges established views on the severity, etiology, and treatment of chronic active hepatitis (the more aggressive form of chronic hepatitis, as contrasted with chronic persistent hepatitis). Using computerized data from dozens of San Francisco Bay area physicians, a team led by gastroenterologist David Altman, MD, found that patients with chronic active hepatitis in the Bay Area are not as ill as those usually described. The team also identified far more cases that were apparently caused by hepatitis B viral infection than the literature would indicate. These findings may signal the need to reevaluate the standard treatments for chronic active hepatitis. Altman's team reported its findings at the recent meeting of the Association of American Physicians in Washington, DC. Striking more than 2,000 Americans each year, chronic active hepatitis can lead to the formation of fibrosis in the