tbuckley/cabot-search huggingface dataset:
“Report Card” Grades for Hospitals Depend on the Methods Used for Reporting
Journal: Annals of Internal Medicine (2000)

Summaries for Patients4 July 2000“Report Card” Grades for Hospitals Depend on the Methods Used for ReportingSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-133-1-200007040-00024 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?A growing number of “report cards ” try to grade the quality of care provided by hospitals by assessing patients' outcomes (for example, death rates). It is hard to develop report card grades that reflect the true quality of care delivered at a particular hospital, however, partly because patients at some hospitals are sicker to begin with, and thus are more likely to have bad outcomes, than those at other hospitals. To deal with this problem, report cards can take patients' level of sickness into account by using ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Results of Report Cards for Patients with Congestive Heart Failure Depend on the Method Used To Adjust for Severity.” It is in the 4 July 2000 issue of Annals of Internal Medicine (volume 133, pages 10-20). The authors are R.M. Poses, D.K. McClish, W.R. Smith, E.C. Huber, F.L.W. Clemo, B.P. Schmitt, D. Alexander, E.M. Racht, and C.C. Colenda III.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoResults of Report Cards for Patients with Congestive Heart Failure Depend on the Method Used To Adjust for Severity Roy M. Poses , Donna K. McClish , Wally R. Smith , Elizabeth C. Huber , F. Lynne W. Clemo , Brian P. Schmitt , Donna Alexander , Edward M. Racht , and Christopher C. Colenda III Metrics 4 July 2000Volume 133, Issue 1Page: 10KeywordsDeath ratesEmergency departmentHealth care qualityHeart failureHospital medicineLongitudinal studiesMedical conditionsMyocardiumResearch quality assessmentRisk management ePublished: 15 August 2000 Issue Published: 4 July 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.Loading ...
Expression and localization of the small and large delta antigens during the replication cycle of hepatitis D virus
Authors: J Wu
Journal: Hepatology (1992)

To study the expression and localization of delta antigen during the replication cycle of hepatitis D virus, we cotransfected HuH-7 hepatoma cells with a hepatitis B virus expression plasmid and plasmids expressing the small or large delta antigen or the entire HDV genome. The transfected cells and culture medium were analyzed on double immunofluorescence staining for delta antigen and HBsAg, on Western blotting and on Northern-blot hybridization from 4 hr to 9 days after transfection. In cells transfected with the expression plasmid carrying the small delta antigen open reading frame, only the small delta antigen was expressed; it was localized in the nucleolus and was not released into the medium during the culture period. In cells transfected with the large delta antigen expression plasmid, the large delta antigen expressed was localized in the nucleolus at the initial stage; this was followed by relocalization in nucleoplasm. Finally, large delta antigen was released in HBsAg-enveloped particles within 1 day of transfection. In cells cotransfected with hepatitis B virus and hepatitis D virus expression plasmids, the small delta antigen was expressed 4 hr after transfection, whereas the large form was expressed 3 days after transfection. Expression of the large delta antigen coincided with the localization changes from nucleolar to mixed stage and, finally, to nucleoplasm and release of the hepatitis D virus particles. The large delta antigen appears to play a key role in relocalization of the delta antigen and packaging of the hepatitis D virus virions. However, early expression of the large delta antigen suppressed hepatitis D virus replication, resulting in the release of defective particles containing an excess amount of the large delta antigen devoid of hepatitis D virus RNA. (HEPATOLOGY 1992;16:1120–1127.)
Late Outcome After Arterial Switch Operation for Transposition of the Great Arteries
Authors: J. Losay, A. Touchot, A. Serraf, A. Litvinova, V. Lambert, J.D. Piot, F. Lacour-Gayet, A. Capderou, C. Planche
Journal: Circulation (2001)

Background Early and midterm results of the arterial switch operation (ASO) in transposition of the great arteries (TGA) are good, but late outcome data in large populations are still few. Methods and Results Twelve hundred patients had an ASO for TGA between 1982 and 1999, with prospective follow-up of 1095 survivors. Outcome measures included late death, reoperation, aortic insufficiency (AI), pulmonary stenosis (PS), and coronary anomaly. Median follow-up was 4.9 years (range 0.5 to 17 years). Late death occurred in 32 patients; survival was 88% at both 10 and 15 years. The hazard function for death declined rapidly, with no deaths after 5 years. Late mortality was correlated with reintervention and major events in the intensive care unit. Reoperation was performed in 103 patients, more often in complex TGA; the cause was mainly PS. Freedom from reintervention was 82% at 10 and 15 years, with a hazard function that declined rapidly but slowly increased after 3 years. At the last follow-up, PS was present in 3.9% of patients, and grade II or more AI was present in 3.2%, with a cumulative incidence of 9% at 15 years. Among the 278 patients who had a coronary arteriography, 8% had coronary lesions. Normal left ventricle and sinus rhythm were seen in 96.4% and 98.1%, respectively. Conclusions Fifteen years after ASO, late mortality was low, with no deaths after 5 years; reoperation, mainly owing to PS, occurred throughout the follow-up. AI and coronary obstruction are rare but warrant further follow-up. Good left ventricular function and sinus rhythm are maintained.
ACUTE PNEUMONITIS
Authors: WILLIAM H.  ALLEN
Journal: Annals of Internal Medicine (1936)

Article1 October 1936ACUTE PNEUMONITISWILLIAM H. ALLEN, M.D., F.A.C.P.WILLIAM H. ALLEN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-10-4-441 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIt is doubtful if there is anything in medicine presenting greater difficulty in classification than the so-called respiratory diseases. In every outbreak the problem arises when to cease the use of such terms as nasopharyngitis and acute bronchitis in order to adopt the equally indefinite one of influenza. One is confronted with the same difficulty in placing the pneumonias, though some progress is being made toward adoption of an etiological classification. It is with no wish to add to the prevailing confusion that we have found it useful to classify as acute pneumonitis a group of cases characterized by signs...Reference1. BOWEN A: Acute influenzal pneumonitis, Am. Jr. Roent. and Radium Therap., 1935, xxxiv, 168-174. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Fort Sam Houston, Texas*Read by invitation before the Texas Club of Internists, San Antonio, Texas, February 21, 1935. Received for publication April 15, 1936.From the Medical Service, Station Hospital, Fort Sam Houston, Texas. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDie Bedeutung der Mycoplasmen für den Menschen unter besonderer Berücksichtigung der Erkrankungen des Respirationstraktes durch Mycoplasma pneumoniaeUnspezifische Entzündungen der LungeQ-FieberQ-FieberMycoplasma and Adenovirus Pneumonias Comparison with Other Atypical Pneumonias in a Military PopulationRONALD B. GEORGE, M.D., MORTON M. ZISKIND, M.D., F.A.C.P., JAMES R. RASCH, WILLIAM J. MOGABGAB, M.D., F.A.C.P.Respiratorische VirenDie PneumonienPneumonia seen in Infantile ParalysisGebräuchliche Methoden zur Untersuchung der Ausgangsmaterialien und Hilfsmittel für die Herstellung der Plast-RohstoffeKlinik der RickettsiosenKlinik der RickettsiosenFamily Epidemic of Primary Atypical PneumoniaAtypical PneumoniaPRIMARY ATYPICAL PNEUMONIAPrimary Atypical PneumoniaMEASURING UP THE MISFITSATYPICAL PNEUMONIAAcute Diseases of the Respiratory System: Differential Diagnosis of the Pneumonias and Other Common Acute Pulmonary ConditionsThe Chronic Pneumonias 1 October 1936Volume 10, Issue 4Page: 441-446KeywordsBronchitisCommon coldMedical servicesPneumoniaPneumonitisPulmonary diseases ePublished: 1 December 2008 Issue Published: 1 October 1936 PDF downloadLoading ...
Coronary Artery Calcium Score Combined With Framingham Score for Risk Prediction in Asymptomatic Individuals
Authors: Diego Ize-Ludlow, Sean Ragone, Jeffrey Bernstein, Michael Duchowny, Barbara Pen ˜a
Journal: JAMA (2004)

Analysis by LC-MS of the sesquiterpene lactone fraction of each sample was performed to determine the presence of anisatin, neoanisatin, and veranisatins A, B, and C. Anistatin and neoanisatin are potent neurotoxins found in I anisatum. 4Although I verum is considered safe for consumption, this species also contains the toxic compounds, veranisatin A, B, and C. 7 Anisatin compounds are thought to act as picrotoxin-like noncompetitive ␥-aminobutyric acid (GABA) antagonists. 8The mass spectral pattern of each sample was similar in the number, type, and concentration of these compounds.Extracts from the third case, however, suggested the presence of an Illicium species other than I verum.Comment.Given our laboratory findings, the symptoms we have described may be attributed to an overdose of I verum, contamination with I anisatum, or a combination of both.Illicium verum has been considered safe because it contains veranisatins in low concentrations. 7However, relatively small quantities in infants may be sufficient to produce adverse neurologic reactions. 9ngestion of star anise should be considered in the differential diagnosis of infants presenting with acute-onset irritability, vomiting, and seizures.Based on these cases and the finding of I verum contamination, we recommend against administering star anise to infants.Stricter regulation may also be warranted.
Annual Reprint of the Reports of the Council on Pharmacy and Chemistry of the American Medical Association for 1924.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
High-Throughput Sequence Analysis of the Tyrosine Kinome in Acute Myeloid Leukemia.
Authors: Marc Loriaux, Ross Levine, Jeffrey Tyner, Stephan Frohling, Claudia Scholl, Eric Stoffregen, Gerlinde Wernig, Heidi Erickson, Chris Eide, Roland Berger, Olivier Bernard, James Griffin, Richard Stone, Matthew Meyerson, Michael Heinrich, Michael Deininger, Gary Gilliland, Brian Druker
Journal: Blood (2007)
PP65. LOW-GRADE GLIOMA WITH FOCI OF EARLY TRANSFORMATION BEHAVING IN AN INDOLENT FASHION FOLLOWING EXTENSIVE SURGICAL RESECTION
Authors: Mr Yahia Al-tamimi, Dr Martin Palin, Dr Stuart Currie, Dr Daniel O’hara, Dr Tufail Patankar, Dr Jeremy Macmullen-price, Dr Carmel Loughrey, Dr Azzam Ismail, Dr Arundhati Chakrabarty, Dr Paul Roberts, Mr Ryan Mathew, Prof Hugues Duffau, Mr John Goodden, Mr Paul Chumas
Journal: Neuro-Oncology (2017)

BACKGROUND: Low-grade glioma (LGG) is a slow-growing tumour often found in young adults. Most present with epilepsy, but others can have minimal or no symptoms. LGG is a heterogenous term applied to WHO Grade 1 tumours and WHO Grade 2 gliomas (G2G). As opposed to true ‘low-grade’ lesions like dysembryoplastic neuroepithelial tumours (DNET), G2G are associated with continuous growth and malignant transformation. METHOD: Prospective database analysis of patients treated for LGG at Leeds General Infirmary from 2010–2015 (5.5 years). Inclusion criteria: patients where pathological analysis of excised tumour showed small isolated foci of high-grade transformation within a background of G2G. RESULTS: Since 2010, 130 LGG resections were undertaken in Leeds (77 awake, 53 asleep). Six patients were identified with foci of transformation within a background G2G. These patients were offered a choice between the conventional strategy of upfront adjuvant therapy or an alternative strategy of close monitoring with serial MRI scans. Three patients have had repeat surgery (two to complete the resection, one for tumour growth after 3-years). To date, none have exhibited further high-grade change within the residual tumour or surrounding area. CONCLUSION: We describe a small subset of patients with LGG that have foci of high-grade glioma but exhibited behaviour and growth tendencies similar to G2G. So far, surgical excision alone has been sufficient to control tumour growth without adjuvant therapy. This finding supports the use of early aggressive surgical treatment of G2G. It also throws into question the optimal timing of adjuvant therapy after resection of these tumours. This also confirms that these tumours are pre-malignant and should be made distinct in classification and name from true low-grade (Grade 1) tumours. Therefore we suggest changing the nomenclature of G2G from LGG to Pre-Malignant Glioma whilst reserving the term LGG for Grade 1 lesions.
Emerging Bacterial Zoonotic and Vector-Borne Diseases
Authors: David H. Walker
Journal: JAMA (1996)

Among the etiologic agents of emerging infectious diseases are several bacterial organisms that naturally reside in animal and arthropod hosts. The most compelling emerging bacterial zoonotic and vector-borne diseases in the United States are Lyme disease; a Southern erythema migrans—like illness; human monocytic ehrlichiosis; human granulocytic ehrlichiosis; a novel cat flea—associated typhus group rickettsiosis; bartonelloses of immunocompetent and immunocompromised persons, particularly with AIDS; and sylvatic plague. Some of these antimicrobial-treatable infections are life threatening. During the acute stage of illness when antimicrobial agents are most effective, the flulike clinical signs and symptoms and available laboratory tests frequently do not point to a particular diagnosis. Epidemiological factors determined by the ecology of the bacteria are often the most useful diagnostic clues. The recognition of these evolving problems emphasizes the need for development of better laboratory diagnostic methods, for surveillance for and tracking of disease, and for continued research into factors contributing to transmission of the organisms. The continual appearance of previously unidentified bacterial infections requires prospective national strategies for timely recognition of the syndrome, identification of the agent, establishment of criteria and methods for diagnosis, optimization of the treatment regimen, and determination of successful approaches to prevention and control. (<i>JAMA</i>. 1996;275:463-469)
SUBACUTE SPASTICITY
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Bar soap and liquid soap
Authors: J. E. Heinze
Journal: JAMA (1984)

<h3>To the Editor.—</h3> The article by Durack et al reports 52 cases of apparent endocarditis prophylaxis failure. Two of their conclusions we found particularly interesting. First, endocarditis prevention failures are not rare. Second, failure of attempted endocarditis prophylaxis may occur even when the organism is sensitive in vitro to the antibiotic used. In 63% of their reported cases for which antimicrobial susceptibility data were available, the infecting organism was susceptible to the antibiotic used for prophylaxis. While most patients received prophylaxis regimens now regarded as inadequate, five patients infected with viridans streptococci received a recommended American Heart Association antibiotic regimen as prophylaxis. Four of those strains were susceptible to the antibiotic given. In one strain, the sensitivity pattern was unknown. It is not clear, however, by which method susceptibility was determined. This becomes very important when considering the concept of tolerance. Tolerant organisms are those that are inhibited at standard
Patent ductus arteriosus. Study of two families
Authors: H. T. Lynch
Journal: JAMA (1965)

Patent ductus arteriosus (PDA) has been found in several members in consecutive generations of two families. In one family the proband's father had affected children through two matings with unrelated wives. In both families, operation confirmed the PDA in each case in two generations. However, in the second family, a maternal great aunt of the proband had characteristic clinical findings, thus making three generations affected. This sequence is best explained by autosomal dominant inheritance with a high degree of specificity. Two other mechanisms for production of PDA seem well established by other studies: (1) maternal rubella and (2) a recessive characteristic. Further family studies are needed to clarify the exact mode of inheritance.
Authors’ Reply
Authors: Pablo E. Pergola, David P. Rosenbaum, Yang Yang, Glenn M. Chertow
Journal: Journal of the American Society of Nephrology (2021)

We thank Dr. Kulkarni for the insightful comments about our manuscript. The randomized trial of tenapanor and phosphate binders as a dual-mechanism treatment for hyperphosphatemia in patients on maintenance dialysis[1][1] evaluated the effect of addition of the intestinal phosphate absorption
THE PHYSICIAN AND THE HOSPITAL.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MUMPS MENINGITIS
Authors: JULIUS KAUNITZ
Journal: JAMA (1918)

The most frequent complication seen in mumps is orchitis. The rarer complications are meningitis, encephalitis, neuritis, ovaritis, endocarditis, arthritis, nephritis, mastitis and vulvovaginitis. The complications appear in most instances in from four to seven days. The meningitis of mumps is very little known. There is mention of 150 cases, although I have not been able to find more than thirty described, most of them appearing in an article by Acker,<sup>1</sup>in which two of his own cases are reported. During some epidemics, there appear to be more meningeal complications than in others. As most patients recover after a few days' illness, it is very probable that the meningeal condition is lost sight of, particularly in the milder cases. This very likely accounts for the fact that so few cases are on record and that so little is known of this complication. The pathology, as found in the necropsies compiled
The Public and Public Health.
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal