tbuckley/cabot-search huggingface dataset:
Biliary tract disorders
Journal: Hepatology (1995)

While various nanoparticles are being increasingly utilized in many sectors of the economy, there is growing interest in the environmental and biological safety linked to their preparation. Green nanotechnology provides tools for the transformation of biological systems to green approaches to nanomaterial synthesis, while preventing any associated toxicity. Due to the large number of toxic chemicals and extreme environments employed in the physicochemical production of these nanoparticles, green methods employ the use of biological sources. Through integrating the principles of green chemistry and engineering, green nanotechnology can produce safe and eco-friendly metal nanoparticles that do not use toxic chemicals in their synthesis. This chapter is a comprehensive study of the types of phytochemicals used in the synthesis of nanoparticles including proteins, polysaccharides, vitamins, glycosides, essential oils, and phenolic-based chemicals. It also provides the preparation methods used for different biological sources. Generally, the main role of natural plant biomolecules is involved with the bioreduction of metal salts during nanoparticle preparation. Furthermore, this chapter provides important examples of the effective use of plant extracts to obtain biosynthesized nanoparticles.
The Intervertebral Disc with Special Reference to Rupture of the Annulus Fibrosus with Herniation of the Nucleus Pulposus
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hepatocyte growth factor and c-met expression in Long-Evans Cinnamon rats with spontaneous hepatitis and hepatoma
Authors: N Nakayama
Journal: Hepatology (1996)

The Long-Evans Cinnamon (LEC) rat is characterized by the spontaneous onset of acute and chronic hepatitis, followed by occurrence of liver cancer, and is thus able to provide a unique experimental model for human genetical liver disease, Wilson's disease. Hepatocyte growth factor (HGF) is a potent hepatotrophic factor in liver regeneration, and its expression is up-regulated in response to liver injuries. We found that the plasma HGF level in LEC rats rose markedly during the fulminant hepatitis phase, fell during the phase of chronic/cholangiofibrosis, and fluctuated during the hepatoma phase. Immunohistological staining of the liver revealed that the number of HGF-positive cells increased remarkably during the fulminant hepatitis phase, and that many of these cells were localized at the portal triads. Fewer HGF-positive cells were observed during the phase of chronic hepatitis. The surface of the hepatocellular carcinoma (HCC) cells and the cytoplasm of the nonepithelial cells in cancerous liver tissues were HGF-positive. The HGF-messenger RNA (mRNA) level in the liver rose in the fulminant hepatitis phase, fell in the chronic hepatitis phase, and was intermediate or high during the hepatoma phase. The expression of c-met mRNA was strong in the tissues of LEC rats with fulminant hepatitis and, especially, in the cholangiofibrosis tissues. c-met mRNA was also detected in HCCs. These results suggest that the HGF-c-met system may play an important role in the regeneration of hepatocytes as well as in the development of HCC in paracrine or autocrine mechanisms.
Abstract 2466: Transapical Aortic Valve Implantation At One Year
Authors: Thomas Walther, Volkmar Falk, Michael A Borger, Jörg Kempfert, Jens Fassl, Yvonne Rückert, Ardawan Rastan, Axel Linke, Gerhard Schuler, Friedrich W Mohr
Journal: Circulation (2007)

Objective: To evaluate the results of minimally invasive transapical aortic valve implantation (TAP-AVI) at one year follow-up. Methods: 61 high risk patients with symptomatic aortic valve stenosis received TAP-AVI at our institution since 02/2006. A pericardial xenograft fixed within a stainless steel, balloon expandable stent (Edwards SAPIEN™ THV, Edwards Lifesciences, Irvine, CA, USA) was used. All valves were implanted in a hybrid operative theatre under fluoroscopic and echocardiographic guidance. Patient age was 82.7 ±4.5 years, 79% were female, NYHA class was 3.4 ±0.5, previous cardiac surgery had been performed in eight patients, logistic EuroSCORE risk for mortality was 28.1 ±11.9% and STS score risk for mortality was 15.9 ±8.6%. Results: TAP-AVI was performed successfully in 58 (95.1%) of the patients; three patients required early conversion due to proximal dislocation, secondary dissection of the aortic root and main stem occlusion. Two of the converted patients were discharged alive. A total of 73.7% of the patients were treated completely off-pump, secondary use of cardiopulmonary bypass was required in 3/39 (7.8%). 82% of the patients were extubated early after 80 ±17min. Echocardiography revealed good valve function; trivial to mild (1°), paravalvular incompetence was present in 41%. At thirty days four (6.6%) patients and during follow-up eight patients (15.3%) died, all with good valve function at most recent echo. Thirty day survival was 93 ±3.4%, six months survival 74.4 ±6.6% and one year survival 70.5 ±7.3%, respectively. There were no neurological events. Conclusions: Transapical aortic valve implantation is a safe, minimally invasive and off-pump technique to treat high risk patients with aortic stenosis. One year results are good, especially when considering the overall risk profile of these patients.
Tumor Epidermal Growth Factor Receptor Studies in Patients With Non-Small-Cell Lung Cancer or Head and Neck Cancer Treated With Monoclonal Antibody RG 83852
Authors: Roman Perez-Soler, Nicholas J. Donato, Dong M. Shin, Michael G. Rosenblum, Hua-Zhong Zhang, Carmen Tornos, Hanna Brewer, James C. Chan, Jin Soo Lee, Waun K. Hong, James L. Murray
Journal: Journal of Clinical Oncology (1994)

The Acknowledgment regarding the report "Tumor Epidermal Growth Factor Receptor Studies in Patients With Non-Small-Cell Lung Cancer or Head and Neck Cancer Treated With Monoclonal Antibody RG 83852" (J Clin Oncol 12:730–739, 1994) should have read as follows: "We thank Dr Chris Tarr, Rhône-Poulenc/Rorer, and Dr Jon Holmlund, National Cancer Institute, for supplying RG 83852; Trupti Shah, Lora B. Thompson, Margaret Janus, Marc Lewis, and M. Perez for skillful technical assistance; and Kevin Flynn for editorial assistance."
RUSSIAN EXPERIENCES WITH LEGALIZED ABORTION
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Health profile of adult special immigrant visa holders arriving from Iraq and Afghanistan to the United States, 2009–2017: A cross-sectional analysis
Authors: Gayathri S. Kumar, Simone S. Wien, Christina R. Phares, Walid Slim, Heather M. Burke, Emily S. Jentes
Journal: PLoS Medicine (2020)

Between 2,000 and 19,000 Special Immigrant Visa (SIV) holders (SIVH) from Iraq and Afghanistan resettle in the United States annually. Despite the increase in SIV admissions to the US over recent years, little is known about the health conditions in SIV populations. We assessed the burden of select communicable and noncommunicable diseases (NCDs) in SIV adults to guide recommendations to clinicians in the US.We analyzed overseas medical exam data in Centers for Disease Control and Prevention's (CDC) Electronic Disease Notification system (EDN) for 19,167 SIV Iraqi and Afghan adults who resettled to the US from April 2009 through December 2017 in this cross-sectional analysis. We describe demographic characteristics, tuberculosis screening results, self-reported NCDs, and risk factors for NCDs (such as obesity and tobacco use). In our data set, most SIVH were male (Iraqi: 59.7%; Afghan: 54.7%) and aged 18-44 (Iraqi: 86.3%; Afghan: 95.6%). About 2.3% of Afghan SIVH and 1.1% of Iraqi SIVH had a tuberculosis condition. About 0.3% of all SIVH reported having chronic hepatitis. Among all SIVH, 56.5% were overweight or had obesity, 2.4% reported hypertension, 1.1% reported diabetes, and 19.4% reported current or previous tobacco use. Iraqi SIVH were 3.7 times more likely to have obesity (95% CI: 3.4-4.0), 2.5 times more likely to report diabetes (95% CI: 1.7-3.5), and 2.5 times more likely to be current or former smokers (95% CI: 2.3-2.7) than Afghan SIVH. Limitations include the inability to obtain all SIVH records, self-reported medical history of NCDs, and the underdiagnosis of NCDs such as hypertension and diabetes because formal laboratory testing for NCDs is not used during overseas medical exams.In this analysis, we found that 56.5% of all SIVH were overweight or had obesity, 2.4% reported hypertension, 1.1% reported diabetes, and 19.4% reported current or previous tobacco use. In general, Iraqi SIVH were more likely to have obesity, diabetes, and be current or former smokers than Afghan SIVH. State public health agencies and clinicians doing domestic screening examinations of SIVH should consider screening for obesity-as per the CDC's Guidelines for the US Domestic Medical Examination for Newly Arriving Refugees-and smoking and, if appropriate, referral to weight management and smoking cessation services. US clinicians can consider screening for other NCDs at the domestic screening examination. Future studies can explore the health profile of SIV populations, including the prevalence of mental health conditions, after integration into the US.
The primary F.R.C.S. examination--a fresh look.
Journal: BMJ (1969)

Napoleon and the Plague-Hibbott MEDICALJOURNAL flamed and suppurate. . .If the buboes do not suppurate deterioration is rapid, and the patient dies between the third and fifth day."Rich Venetian colours fill the painting-in the robes of the Arabs and Turks, and uniforms of the officers-reflecting the artist's studies in Italy.The painting marked a turning-point in Gros's career.Previously painting in the style of David's austere classicism, he now broke away to become the pre- cursor of the French romantic school.Gros completed the painting in less than six months, work- ing alone in his studio at Versailles.He would admit no one, and had no assistance despite his increased suffering from rheumatism.The painting caused a sensation when it was exhibited at the Salon of September 1804, soon after its com- pletion.
Cluster of Tuberculosis Cases Among Exotic Dancers and Their Close Contacts--Kansas, 1994-2000
Journal: JAMA (2001)

During January 2001, the Wichita-Sedgwick County Department of Community Health (WSCDCH), the Kansas Department of Health and Environment (KDHE), and CDC investigated a cluster of tuberculosis (TB) cases that occurred from 1994 to 2000 among women with a history of working as dancers in adult entertainment clubs (i.e., exotic dancers) and persons who were close contacts of exotic dancers. This report describes the results of the investigation and illustrates the need for early identification of TB clusters through ongoing surveillance and resources for health departments to respond rapidly to TB outbreaks.
Highlights
Journal: JAMA (2015)

ICD Use In Patients With Low Ejection Fraction After MI 2433Implantable cardioverter-defi brillators (ICDs) are not recommended in the fi rst 6 weeks after myocardial infarction (MI), and uncertainties regarding eff ectiveness and procedural risks may discourage ICD use among older adults.In an analysis of 2007-2010 registry data from 10 318 Medicare benefi ciaries with low ejection fraction after MI, Pokorney and colleagues found that fewer than 1 in 10 eligible patients received an ICD in the year after MI, despite lower risk-adjusted mortality associated with ICD implants.In an Editorial, Hauser discusses underutilization of ICDs in older patients.
Surgery, Gynecology, and Obstetrics, Chicago
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Accrual of underrepresented minority women to breast cancer clinical trials in the Inland Empire, California.
Authors: Y. Yuan, P. Uppala, S. S. Lum, C. Garberoglio, H. R. Mirshahidi, R. Cassady, J. Morgan, C. Chen
Journal: Journal of Clinical Oncology (2011)

9058 Background: Ethnic minority women are currently underrepresented in cancer clinical trials. The age-adjusted incidence and mortality rates for breast cancer are higher in Riverside and San Bernardino Counties than the statewide average. During the 10 years of enrollment at Loma Linda University Cancer Center (LLUCC) between 1999 and 2009, we enrolled a total of 151 patients to breast cancer clinical trials. Among the enrolled patients, only 26.7% were ethnic minority women in contrast with the 59% of ethnic minority women living in the Inland Empire. Methods: A countywide breast cancer awareness campaign using television, radio, billboard, and print ads was combined with direct mail sent to regional physician offices and breast imaging centers. We specifically addressed previously identified barriers to participation in clinical trials, such as lack of medical insurance, time, invitation, awareness of available studies, access to the institution or doctors conducting the trial, and coordination among clinics. In addition, we utilized a culturally sensitive multidisciplinary team to address the breast cancer care for minority women. Results: During the one year period since implementation of the regional culturally sensitive breast cancer awareness campaign, we successfully enrolled 18 patients into breast cancer clinical trials. The minority breast cancer patient accrual increased from a 10 year average of 26.7% to 50%. The accrual rate of Hispanic population was increased from 10% to 16.7%. The accrual rate of the non-Hispanic black tripled from 5.3% to 16.7%. Conclusions: The use of materials specifically targeting known barriers to participation in clinical trials successfully improved accrual of minority women, and has the potential to improve the cure rate, decrease disparities in breast cancer care, and eventually decrease the breast cancer burden particularly in underserved minority groups in Inland Empire.
Knots
Authors: David O. Parrish
Journal: JAMA (1981)

<h3>To the Editor.—</h3> After reading such an interesting COMMENTARY on knots and their practical as well as symbolic meaning to the practice of medicine, I was appalled that both the author, Richard M. Ratzan, MD (1980;244:2615), and the reference staff of the West Hartford (Conn) Public Library believe the caduceus to be the symbol of the medical profession. The caduceus is mistakenly used by many, most notably the US Army, as the symbol of the medical profession. The US Army uses the caduceus for its medical personnel probably based on its use during wars by Hermes and Mercury as a symbol of neutrality.<sup>1</sup>The staff of Aesculapius is the true symbol of the medical profession historically and was adopted by the American Medical Association in 1910 as its official symbol. I hope this mistake will not go uncorrected.
Ubiquitous macrophages—in cancer, atherosclerosis
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Child and adolescent health in the digital age
Authors: None The Lancet Digital Health
Journal: The Lancet Digital Health (2020)

On 18 February, 2020, The Lancet published the report of the WHO-UNICEF-Lancet Commission, calling for a refocus of the Sustainable Development Goals (SDGs) around child and adolescent health. All sectors are responsible for children's wellbeing, with digital platforms and artificial intelligence (AI) playing an increasing role in child and adolescent health.
Erratum for the Research Article: “Somatic <i>PIK3CA</i> mutations as a driver of sporadic venous malformations” by P. Castel, F. J. Carmona, J. Grego-Bessa, M. F. Berger, A. Viale, K. V. Anderson, S. Bague, M. Scaltriti, C. R. Antonescu, E. Baselga, J. Baselga
Journal: Science Translational Medicine (2018)
Sertraline for Treatment of Depression in Acute Coronary Syndromes—Reply
Authors: Alexander H. Glassman, Christopher M. O'Connor
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Postmortem Examinations in Medico=legal and Ordinary Cases, with special chapters on the legal aspects of postmortems and on certificates of death.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tips for teaching evidence-based medicine in a clinical setting: lessons from adult learning theory. Part one
Authors: Kausik Das, Sadia Malick, Khalid S Khan
Journal: Journal of the Royal Society of Medicine (2008)

Summary Evidence-based medicine (EBM) is an indispensable tool in clinical practice. Teaching and training of EBM to trainee clinicians is patchy and fragmented at its best. Clinically integrated teaching of EBM is more likely to bring about changes in skills, attitudes and behaviour. Provision of evidence-based health care is the most ethical way to practice, as it integrates up-to-date, patient-oriented research into the clinical decision making process, thus improving patients' outcomes. In this article, we aim to dispel the myth that EBM is an academic and statistical exercise removed from practice by providing practical tips for teaching the minimum skills required to ask questions and critically identify and appraise the evidence and presenting an approach to teaching EBM within the existing clinical and educational training infrastructure.