tbuckley/cabot-search huggingface dataset:
Manual of Materia Medica and Pharmacy. Specially Designed for the Use of Practitioners and Medical, Pharmaceutical, Dental and Veterinary Students.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Accelerated partial-breast irradiation using brachytherapy (APBIb) for breast cancer (BCA): Predictors of use and guideline concordance.
Authors: J. A. Hattangadi, N. Taback, B. A. Neville, J. R. Harris, R. S. Punglia
Journal: Journal of Clinical Oncology (2011)

6080 Background: APBIb is an alternative to whole breast irradiation (WBI) after breast conserving surgery (BCS). We evaluated patterns of APBIb use with respect to treatment suitability criteria defined by 2009 American Society for Radiation Oncology consensus guidelines (ASTRO-G) in a population based cohort. Methods: 138,815 patients diagnosed from 2000-2007 with non-metastatic bca who underwent WBI or APBIb after BCS were identified from the Surveillance, Epidemiology and End Results database. Patients were classified as “suitable,” “cautionary,” or “unsuitable” for APBIb according to ASTRO-G. Multivariable logistic regression analysis was applied to study APBIb use in the overall cohort and in each guideline category. Results: Overall, 2.6% of the cohort received APBIb, and use varied by ASTRO-G category: 5% of suitable patients, 3.4% of cautionary patients, and 1.6% of unsuitable patients (p<0.0001). APBIb use increased from 0.3% in 2000-2 to 5.5% in 2006-7 and varied widely with U.S. region (0% in Alaska, 7% in Atlanta, Georgia). Independent predictors of APBIb among suitable patients included white (odds ratio (OR) 2.0, p<0.001) and black (OR 1.9, p<0.01) race, region (OR 2.6-8.6, p<0.0001), later treatment year (2006-7 v 2000-2 OR 20.3, p<0.0001), lower grade disease (OR 1.3, p=0.01), and sentinel lymph node biopsy (SLNB) (OR 1.3, p<0.0001). Among cautionary patients, white race (OR 1.8, p<0.001), non-Hispanic ethnicity (OR 1.3, p<0.04), region (OR 2.6-10.2, p<0.0001), metropolitan location (OR 1.9, p=0.01), later treatment year (2006-7 OR 17.6, p<0.0001), lower grade disease (OR 1.4, p<0.0001), and SLNB (OR 1.6, p<0.0001) predicted for APBIb. Among unsuitable patients, race (p<0.0001), region (OR 3.3-21.5, p<0.0001), later treatment year (2006-7 OR 12.6, p<0.0001), estrogen receptor positive status (OR 1.3, p=0.002), lower grade disease (OR 1.3, p<0.01), type of nodal surgery (p<0.0001), and negative lymph nodes (OR 2.0, p<0.0001) predicted for use. Conclusions: APBIb after BCS has been rapidly adopted in the U.S. Its use varied by race, ethnicity, and widely by region especially among patients who may not be suitable candidates for this radiation technique.
Lymphoblastoid interferon-? with or without steroid pre-treatment in children with chronic hepatitis B: A multi-centre controlled trial 1Dept of Child Health, King's College School of Medicine and Dentistry, London, UK; 2Hospital Infantil La Paz, Madrid, Spain; 3Dipartimento di Pediatria, Universit� Degli Studi di Napoli Federico II, Naples, Italy; dClinica Medica 2, Universit� di Padova, Padua, Italy
Journal: Hepatology (1995)
Tobacco Use in Vietnam
Authors: Christopher N. H. Jenkins
Journal: JAMA (1997)

<h3>Objective.</h3> —To describe tobacco use in Vietnam and the impact of transnational tobacco corporations there. <h3>Desig.</h3> —In cities, a multistage cluster design; in communes, a systematic sample design, using face-to-face interviews in all sites. <h3>Setting.</h3> —Hanoi, Ho Chi Minh City, and 2 rural communes in Vietnam. <h3>Participants.</h3> —Random samples totaling 2004 men and women aged 18 years or older. <h3>Main Outcome Measures.</h3> —Prevalence and correlates of tobacco smoking, amount and duration of smoking, age at initiation, quitting behavior, knowledge of health hazards of and attitudes toward smoking, and cigarette brand smoked, preferred, and recognized as most widely advertised. <h3>Results.</h3> —Smoking prevalence among men (n=970) was 72.8% and 4.3% among women (n=1031). Male smokers had smoked a mean of 15.5 years; the median age at initiation was 19.5 years. Among male smokers, 16% smoked non-Vietnamese cigarettes. More than twice as many (38%), however, said that they would prefer to smoke a non-Vietnamese brand if they could afford the cost. Among those who recalled any cigarette advertising (38%), 71% recalled a non-Vietnamese brand as the most commonly advertised. Male smokers who were significantly more likely to smoke non-Vietnamese brands lived in the south, were engaged in blue collar or business/service occupations, earned higher incomes, and lived in urban areas. <h3>Conclusions.</h3> —Vietnam has the highest reported male smoking prevalence rate in the world. Unless forceful steps are taken to reduce smoking among men and prevent the uptake of smoking by youth and women, Vietnam will face a tremendous health and economic burden in the near future. Implementation of a comprehensive national tobacco control campaign together with international regulation will be the keys to the eradication of the tobacco epidemic in Vietnam and throughout the developing world.
Some Nations Still Report Polio Rise
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract P2-08-01: Results from a randomized placebo-controlled phase 2 trial evaluating exemestane ± enzalutamide in patients with hormone receptor–positive breast cancer
Authors: I Krop, V Abramson, M Colleoni, FA Holmes, L Estevez, L Hart, A Awada, C Zamagni, P Morris, L Schwartzberg, S Chan, D Wheatley, A Guculp, L Biganzoli, J Steinberg, L Gianni, M Trudeau, CM Kelly, H Uppal, IC Tudor, A Peterson, E Winer, DA Yardley
Journal: Cancer Research (2017)

Abstract This abstract was withdrawn by the authors.
Postoperative Potassium Deficit and Metabolic Alkalosis
Authors: Leonard P. Eliel, Olof H. Pearson, Rulon W. Rawson
Journal: New England Journal of Medicine (1950)

Discussion Evidence of a Tissue Potassium Deficit Hypochloremia resistant to correction by isotonic sodium chloride solution has previously been observed in postoperative patients. Ten years ago, Maddock3 described a group of patients who demonstrated a resistant hypochloremia after operation. Chloride administered as the sodium salt was either excreted in the urine or added to the body with water. These patients exhibited lethargy, depression, weakness, fatigue, anorexia, nausea, dehydration, drowsiness and stupor. Clinical improvement and rise in plasma chloride occurred when the patients started to eat. No explanation was offered. Ariel and his co-workers4 again called attention to this group of . . .
Retraction Note: The helminth product ES-62 protects against septic shock via Toll-like receptor 4–dependent autophagosomal degradation of the adaptor MyD88
Authors: Padmam Puneet, Mairi A McGrath, Hwee Kee Tay, Lamyaa Al-Riyami, Justyna Rzepecka, Shabbir M Moochhala, Shazib Pervaiz, Margaret M Harnett, William Harnett, Alirio J Melendez
Journal: Nature Immunology (2011)
Laser treatment for eye disease
Authors: A. Patz
Journal: JAMA (1983)

Within the past 15 months, the National Eye Institute (NEI) has announced that laser photocoagulation treatment can reduce the risk of blindness in patients with common eye disorders, senile macular degeneration (SMD),<sup>1</sup>and ocular histoplasmosis.<sup>2</sup>In each case, a controlled clinical trial compared vision in laser-treated and untreated patients. In the patients with macular degeneration, after 18 months, 60% of the nontreated eyes compared with only 25% of the treated eyes had progressed to severe vision loss. In the patients with ocular histoplasmosis, after 24 months, 35% of the untreated eyes compared with only 11% of the treated eyes had progressed to severe vision loss. The importance of these findings is underscored by the fact that in this country, macular degeneration is the major cause of legal blindness in the elderly, and ocular histoplasmosis is a significant cause of vision loss in the southeastern and midwestern parts of
THE NEURASTHENIC PATIENT AND THE INTERNIST
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Complications of Staphylococcic Pneumonia in Children
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"AN ABDOMINAL BANDAGE FOR PATIENTS WITH WHOOPING COUGH"
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tularemia and rhabdomyolysis
Authors: A. B. Kaiser
Journal: JAMA (1985)

Rhabdomyolysis as a complication of tularemia occurred in four patients in Tennessee over a four-year period. All patients were severely ill and had renal failure. Tularemia was not suspected initially in any of these patients. One patient died of complications of rhabdomyolysis. At autopsy, multiple abscesses were present within skeletal muscle, suggesting that rhabdomyolysis resulted from direct muscle involvement with<i>Francisella tularensis</i>. Tularemia should be considered in the differential diagnosis of patients with an acute febrile illness and rhabdomyolysis. Conversely, in patients with acute tularemia, the possibility of rhabdomyolysis should be entertained early, especially in those with evidence of myoglobinuria and/or impaired renal function. (<i>JAMA</i>1985;253:241-243)
Non-Hodgkin's lymphoma in patients with advanced HIV infection treated with zidovudine
Authors: R D Moore, H Kessler, D D Richman, C Flexner, R E Chaisson
Journal: JAMA (1991)

We wished to determine the incidence of human immunodeficiency virus—related high-grade non-Hodgkin's lymphoma (NHL) and identify factors associated with the development of NHL in patients receiving zidovudine. Data are from a 2-year prospective, observational, multisite study of 1030 patients with the acquired immunodeficiency syndrome (AIDS) and advanced AIDS-related complex who received zidovudine. Non-Hodgkin's lymphoma developed in 24 (2.3%) of 1030 patients who received zidovudine during 1463 person-years of follow-up (rate, 1.6 per 100 person-years of therapy). The relative hazard for development of NHL was stable throughout 2 years of therapy, with the risk of developing NHL 0.8% for each additional 6 months of therapy. Factors associated with development of NHL were a prior diagnosis of Kaposi's sarcoma, herpes simplex virus infection, or lower mean neutrophil count. Less strongly associated was a prior diagnosis of oral hairy leukoplakia or homosexual transmission of HIV. By Cox proportional hazards analysis, a prior diagnosis of Kaposi's sarcoma, cytomegalovirus disease, or oral hairy leukoplakia was most strongly associated with development of NHL. Our study demonstrates a relatively high incidence of NHL in patients with advanced human immunodeficiency virus disease who are undergoing antiretroviral therapy and suggests possible risk factors for development of NHL. (<i>JAMA</i>. 1991;265:2208-2211)
Genetic epidemiology of HbS in Oman: Multicentric origin for the βS gene
Authors: Shahina Daar, H. Mohamed Hussain, David Gravell, Ronald L. Nagel, Rajagopal Krishnamoorthy
Journal: American Journal of Hematology (2000)

On the basis of a sample of 117 chromosomes, we have demonstrated the multicentric origin of the sickle mutation in Northern Oman. Three major haplotypes coexist: 52.1% Benin (typical and atypicals), 26.7% Arab-India, and 21.4% Bantu. These haplotypes are not autochthonous to Oman but originated elsewhere and arrived in Oman by gene flow. The distribution of haplotypes is in excellent agreement with the historical record, which establishes clear ancient contacts between Oman and sub-Sahara west Africa and explains the presence of the Benin haplotype; contacts with Iraq, Iran, present-day Pakistan, and India explain the presence of the Arab-India haplotype. More recent contacts with East Africa (Zanzibar/Mombasa) explain the presence of the Bantu haplotype. The pattern of the Arab-India haplotype in the populations of the Arabian peninsula reinforces the hypothesis that this particular mutation originated in the Harappa culture or in a nearby population and in addition reveals that the Sassanian Empire might have been the vehicle by which this Indo-European sickle mutation migrated (gene flow) to the present-day Arabian peninsula, including Oman. Am. J. Hematol. 64:39–46, 2000. © 2000 Wiley-Liss, Inc.
Familial Hypercholesterolemia
Authors: David W. Bilheimer
Journal: JAMA (1987)

Familial hypercholesterolemia (FH) is a metabolic disorder that causes premature artherosclerosis.<sup>1</sup>It is transmitted as an autosomal dominant trait, and both heterozygous and homozygous forms of the disease are recognized. The gene frequency for heterozygous FH in the general population is estimated to be one in 500, making it one of the most common simply inherited disorders in man. The hypercholesterolemia results from the excess accumulation of low-density lipoprotein (LDL) in the plasma. The sustained elevation of the LDL-cholesterol level then promotes the development of premature atherosclerosis and xanthoma formation in the tendons and skin. Heterozygotes have LDL-cholesterol levels twofold to threefold above normal and begin experiencing myocardial infarctions in the fourth decade of life. Homozygotes are much more severely affected, having LDL-cholesterol levels sixfold to eightfold above normal and experiencing myocardial infarctions in the first or second decades of life. The pathophysiology of FH is now well understood,
Physical activity and primary cardiac arrest
Authors: D. S. Siscovick
Journal: JAMA (1982)

To explore the relationship between vigorous physical activity and primary cardiac arrest (PCA), we identified, through emergency service incident reports, 163 cases of PCA aged 25 to 75 years. Control subjects matched for age, sex, residence, and the absence of prior clinical heart disease or major comorbidity were identified from the community. Spouses of subjects were interviewed to quantify leisure-time activity (LTA) during the prior year. Energy expended in high-intensity LTA, requiring 60% of maximum oxygen intake, was determined. The risk of PCA was 55% to 65% lower in persons in the two upper quartiles of high-intensity LTA than in persons without high-intensity LTA (95% confidence interval of relative risk, 0.22 to 0.85). Because this association was demonstrated in a clinically healthy population without prior morbidity, our data support the hypothesis that high-intensity LTA protects against PCA. (<i>JAMA</i>1982;248:3113-3117)
Phocomelic Deformity and Maternal Thalidomide Administration: Report of Four Cases
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: BMJ (1924)

work on Cha-les BouchardtI is a valuable contribution to the history of the Paris Faculty of Nledicine in the last quarter of the nineteenth century and first deca(le of the twentieth.Bouchard's medical activities were many and various.In addition to a large consulting practice hewas physician in turn to the Bictre, Lariboisiere, and Charite6 hospitals, in the laicization of which he tool a prominent part.He devoted considerable attention to labora- tory work, in which he had as his assistants Chantemesse, Netter, Widal, Roger, Charrin, Balthazard, and Claude.In 1876 he succeeded Lorain in thle chair of the history of tne(licine, where lhe devote(d a series of lectures to the pro-