tbuckley/cabot-search huggingface dataset:
ANESTHESIOLOGY
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
No link exists between exposure to benzodiazepines in pregnancy and cleft palate
Journal: BMJ (1998)

No link exists between exposure to benzodiazepines in pregnancy and cleft palateConflicting evidence exists about whether first trimester exposure to benzodiazepines increases the risk of major malformations or oral cleft.In their metaanalysis of cohort trials Dolovich et al (p 839) found that fetal exposure to benzodiazepines was not associated with major malformations or oral cleft, but a smaller pooled analysis on the basis of data from casecontrol studies found a significantly increased risk for major malformations or oral cleft.Even if the "worst case scenario" is assumed, benzodiazepines do not seem to be major human teratogens.
Teaching touch at medical school
Authors: J. Older
Journal: JAMA (1984)

The association between touch and healing is ancient and worldwide. Skilled hands are among the physician's most important diagnostic and therapeutic tools. Yet a survey of medical schools in the English-speaking world revealed that most offer no touch training in their curricula. Of 169 medical schools, only 12 give any formal instruction in the uses and meaning of therapeutic touch in medicine. The teaching modes of these 12 schools are discussed, and the program of the most touch-conscious school, the University of Otago, is described. (<i>JAMA</i>1984;252:931-933)
Back Pain Among Persons Working on Small or Family Farms—Eight Colorado Counties, 1993-1996
Journal: JAMA (1999)

In the United States, work-related back pain often results in lost wages, reduced productivity, and increased medical costs. However, national surveillance data about these injuries, such as occupationally acquired back pain among workers on small or family farms, are limited. To characterize back pain in a farming population, researchers at Colorado State University interviewed adult farmers residing in eight northeastern Colorado counties (Larimer, Logan, Morgan, Phillips, Sedgewick, Washington, Weld, and Yuma) during 1993-1996, using the Colorado Farm Family Health and Hazard Survey (CFFHHS). This report summarizes the findings of CFFHHS, which indicate that back pain is common among farmers and most frequently attributed to repeated activities (RAs) (e.g. lifting, pushing, pulling, bending, twisting, and reaching).
Rapid induction of hepatic fibrosis in the gerbil after the parenteral administration of iron-dextran complex
Authors: P Carthew
Journal: Hepatology (1991)

The parenteral administration of iron-dextran complex to gerbils caused hepatic hemosiderosis and fibrosis after 6 wk. Type I and III collagen synthesis in the liver developed from perisinusoidal stellate cells that are often referred to as myofibroblasts. Immunohistologically these cells were shown to have large intracellular deposits of ferritin. The hepatic fibrosis appeared to be associated with aggregates of these cells rather than the aggregates of Kupffer cells, which also occur in hemosiderosis in the liver. No appreciable necrosis of hepatocytes to trigger the fibrotic response was found, so that the fibrosis appeared to be related to the accumulation of ferritin in the perisinusoidal stellate cells. In contrast, rats and mice did not accumulate ferritin in their perisinusoidal cells or develop hepatic fibrosis in response to parenterally administered iron, although they accumulated similar or greater amounts of total iron in their livers. The rapid induction of hepatic fibrosis in gerbils in response to parenterally administered iron will provide a model to investigate the mechanism of induction of collagen deposition in response to iron overload and a means of quickly evaluating therapeutic treatments for iron overload–induced fibrosis in vivo using iron-chelating drugs. (HEPATOLOGY 1991;13:534–539.)
Role of foods in sporadic listeriosis. II. Microbiologic and epidemiologic investigation. The Listeria Study Group
Authors: R. W. Pinner
Journal: JAMA (1992)

<h3>Objective.</h3> —To evaluate the role of foods in sporadic listeriosis. <h3>Design.</h3> —Microbiologic survey of foods collected from refrigerators of patients with listeriosis identified through active laboratory-based surveillance. Patient and food<i>Listeria monocytogenes</i>isolates were subtyped to identify foods contaminated with the same strain of<i>L monocytogenes</i>that caused illness in the patient; samples of these foods were obtained from the retail source. <h3>Setting.</h3> —Multistate population-based study conducted between 1988 and 1990. <h3>Results.</h3> —<i>Listeria monocytogenes</i>grew from at least one food specimen in the refrigerators of 79 (64%) of 123 listeriosis patients; 11% of more than 2000 food specimens collected in the study contained<i>L monocytogenes</i>. Twenty-six (33%) of 79 refrigerators with foods that grew<i>L monocytogenes</i>contained at least one food isolate of the same strain as that in the corresponding patient, a frequency much higher than would be expected by chance (<i>P</i>&lt;.001). Multivariate analysis showed that of the food specimens that grew<i>L monocytogenes</i>, foods that were ready-to-eat, foods that grew<i>L monocytogenes</i>by a direct-plating method (a measure of the level of contamination), and foods that contained serotype 4b isolates were independently associated with an increased likelihood of containing the patient-matching strain. <h3>Conclusion.</h3> —We identified specific food and<i>L monocytogenes</i>isolate characteristics—ready-to-eat foods, foods containing higher concentrations of<i>L monocytogenes</i>, and foods containing serotype 4b—which were associated with disease-causing strains. These results can provide guidance to industry and regulatory agencies in developing strategies to prevent listeriosis. (<i>JAMA</i>. 1992;267:2046-2050)
BOOK REVIEWS
Authors: J. MAIZEL
Journal: JNCI Journal of the National Cancer Institute (1988)

Journal Article BOOK REVIEWS Get access Computer Simulation of Carcinogenic Process B. D. Silverman, ed. Boca Raton, FL: CRC Press, 1988, 176 pp. $124.95 (U.S); $149.00 (Foreign). JACOB MAIZEL, JR. JACOB MAIZEL, JR. Laboratary of Matheatical Biology, Fredrick Cancer Research Facility, National Cancer InstituteBuilding 469, Room 151 Fredrick, MD 21701 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 80, Issue 17, 2 November 1988, Page 1421, https://doi.org/10.1093/jnci/80.17.1421 Published: 02 November 1988
A molecular analysis of viral persistence in surface antigen-negative chronic hepatitis B
Authors: J KATO
Journal: Hepatology (1996)

To identify the mechanisms of viral persistence in patients with chronic hepatitis B after the acquisition of anti-hepatitis B surface antigen antibodies (antiHBs), we serially analyzed the nucleotide sequence of the envelope region in a cohort of infected patients. Four patients with histological diagnoses of chronic hepatitis B who had at least 5 years of observance by our hospital staff were studied. All but one showed normalization of serum alanine aminotransferase (ALT) concentration after clearance of the hepatitis B surface of antigen (HBsAg) and the appearance of anti-HBs. Hepatitis B virus (HBV) DNA was still detectable by polymerase chain reaction (PCR) amplification assay in serum specimens from two patients, even in the presence of circulating anti-HBs. The envelope gene was amplified by PCR in serum samples obtained both before and after seroconversion, and direct cycle sequencing of the PCR products was performed. A mutation resulting in a premature stop codon was found in the pre-S1 region of one patient just prior to clearance of HBsAg. Two years later, the stop codon was converted to a leucine codon and three mutations developed in the "a" loop. In the other patient, 16 amino acids had been deleted between amino acids 8 and 23 in the pre-S2 region before clearance of HBsAg. After the appearance of circulating anti-HBs, the pre-S2 gene reverted to the wild type but three additional mutations appeared inside the "a" loop. These results suggest that HBV mutates when HBsAg is cleared, which may contribute to viral persistence due to an evasion of the host immune surveillance.
MADRID
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The fate of the patient returned to hemodialysis after losing a renal transplant
Authors: A. J. Matas
Journal: JAMA (1983)

Previous reports have suggested that renal allograft recipients have an increased mortality rate when returned to hemodialysis. We studied the survival of patients returned to hemodialysis after losing a renal allograft and compared it with the survival of patients undergoing maintenance hemodialysis during the same period as reported by individual centers in the United States and by the European Dialysis and Transplant Association. Six-year actuarial survival of 83 patients after loss of a first transplant and of 37 patients after loss of two or more transplants compared favorably with data on survival of patients undergoing maintenance dialysis. We conclude that a transplant recipient is not at increased risk when returned to hemodialysis. (<i>JAMA</i>1983;250:1053-1056)
Transactions of the Medical Association of Central New York.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE FIRST HEART SOUND
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
FEDERAL PROTECTION OF THE PUBLIC HEALTH.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Papanicolaou smear screening and cervical cancer. What can you expect?
Authors: B. Stenkvist
Journal: JAMA (1984)

More than 90% of the total female population of three Swedish counties between the ages of 30 and 59 years, 53% of women between 60 and 69 years, and 25% of women older than 70 years were screened for cervical cancer with the Papanicolaou smear over a ten-year period. The uniqueness of the study is that in Sweden it is possible to follow up the entire population during their lifetimes via a population register, which has its roots in the 17th century, natural to Swedes but almost incomprehensible in the United States or United Kingdom. Every Papanicolaou smear taken was computer recorded and linked on an individual level to the cancer registry. There were 207,455 women followed up for ten years. No women were lost to follow-up. There was a 75% decrease in invasive cervical cancer incidence among women who had smears taken at least once during the ten-year period. Among those women who had never had smears taken, the incidence of invasive cervical cancer was four times as great as among those women who had been examined at least once. We estimate that the system proposed by Swedish Medical Board (at least one smear every three years) for cervical cancer screening can reduce the incidence of invasive cervical cancer to a level between one and five cases per 100,000 women per year in a completely screened population. (<i>JAMA</i>1984;252:1423-1426)
Randomized multicenter phase II/III study with adjuvant gemcitabine versus neoadjuvant/adjuvant FOLFIRINOX in resectable pancreatic cancer: The NEPAFOX trial.
Authors: Wael Hozaeel, Claudia Pauligk, Nils Homann, Kim Luley, Thomas Werner Kraus, Jorg Trojan, Wolf O. Bechstein, Kersten Grimm, Bettina Heise, Wolff Schmiegel, Daniel Pink, Salah-Eddin Al-Batran
Journal: Journal of Clinical Oncology (2015)

TPS4152 Background: The outcome of pancreatic cancer remains poor. Few patients (pts) can be assigned to surgery and 80% of resected pts experience a relapse. Currently, adjuvant ctx with gemcitabine is standard, but prognosis remains poor, with 5-year survival rates around 25%. FOLFIRINOX is superior to gemcitabine in the metastatic setting and may represent a valuable option in resectable stages. Therefore, we initiated this multicenter phase II/ III trial (NEPAFOX) to explore the efficacy of neoadjuvant FOLFIRINOX. Methods: This is a randomized phase II/III trial. Pts with locally limited, curatively resectable or borderline resectable adenocarcinoma of the pancreas without metastases are eligible. Eligible pts are randomized to (arm A) surgery followed by adjuvant gemcitabine (1000 mg/m2) for 6 months or (arm B) perioperative FOLFIRINOX (irinotecan 180 mg/m2, oxaliplatin 85 mg/m2, 5-FU 400mg/m² bolus, 5-FU 2400 mg/m², sodium folinate 400 mg/m2) with 6 cycles (12 weeks) pre and further 6 cycles post surgery. Staging includes CT of chest and abdomen and will be repeated after 3 cycles of neoadjuvant chemotherapy, before surgery and every 3 months after surgery. Follow-up will be two years for disease recurrence. As prophylaxis for neutropenia, pts will obtain Filgrastim (Nivestim) ( ≤ 70 kg KG 30MioU/0,5 mL and > 70 kg KG 48 MioU/0,5 mL) s.c. 1-0-0 d 5-7). The primary endpoint is median OS. Secondary endpoints are median PFS, perioperative morbidity and mortality, R0 resection rate, pathological complete remission and prevalence of iron deficiency anemia. 126 pts will be randomized 1:1. After an interims analysis, the trial can be continued as phase III (310 pts). Recruitment of the trial started in Nov 2014. Clinical trial information: NCT02172976.
Reversal of atrial natriuretic peptide resistance by increasing distal tubular sodium delivery in patients with decompensated cirrhosis*1, *2
Authors: W ABRAHAM
Journal: Hepatology (1995)

To test the hypothesis that diminished sodium delivery to the distal tubular site of atrial natriuretic peptide (ANP) action accounts for renal ANP resistance in cirrhosis, 12 cirrhotic patients with ascites were studied at baseline and during the infusion of ANP alone (0.15 μg/kg/min), mannitol alone (4 g/hr), and ANP plus mannitol for 3 hours each. Distal tubular sodium delivery, as assessed by lithium clearance, was increased during the infusion of mannitol (13.8 ± 3.4 to 23.7 ± 5.7 mL/min; P < .05) and during the ANP plus mannitol infusion (13.8 ± 3.4 to 28.5 ± 6.3 mL/min; P < .001) in 6 patients, subsequently termed “responders”. Both responders and non-responders were resistant to the natriuretic effect of ANP infused alone, and mannitol alone did not produce an increase in urinary sodium excretion. However, in responders, the mannitol-induced increase in distal tubular sodium delivery resulted in a fivefold increase in urinary sodium excretion during ANP infusion (29 ± 6 to 154 ± 40 μmol/min, P < .01). Urinary cyclic guanosine monophosphate (cGMP) excretion increased significantly and to a similar extent during ANP and ANP plus mannitol in all 12 patients, supporting the active biological responsiveness of renal ANP receptors. Unlike responders, nonresponders showed a significant decrease in arterial blood pressure and an increase in plasma renin activity during ANP plus mannitol, consistent with worsened arterial underfilling caused by ANP-induced vasodilation. Thus, the present results support the hypothesis that diminished distal tubular sodium delivery is a major factor contributing to ANP resistance in cirrhosis.
Human epidermal Langerhans cells express the ICAM-3 molecule. Immunohistochemical and immunoelectron microscopical demonstration
Authors: G. C. Manara, G. Pasquinelli, L. Badiali-De Giorgi, C. Ferrari, S. A. Garatti, D. Fasano, E. Berti
Journal: British Journal of Dermatology (1996)
Home Monitoring Service Improves Blood Pressure Control in Patients with High Blood Pressure
Journal: Annals of Internal Medicine (2001)

Summaries for Patients5 June 2001Home Monitoring Service Improves Blood Pressure Control in Patients with High Blood PressureSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-134-11-200106050-00005 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?High blood pressure (hypertension) is a common medical problem in adults. Treatments to reduce blood pressure include diet, exercise, and medicines. Lowering blood pressure helps to prevent the complications of high blood pressure, which include heart disease, kidney disease, and stroke. Unfortunately, many people with hypertension either go untreated or receive treatments that do not lower blood pressure enough. New ways of transferring information through telephone lines present opportunities for improving the delivery of health care.Why did the researchers do this particular study?To find out whether ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Home Monitoring Service Improves Mean Arterial Pressure in Patients with Essential Hypertension. A Randomized, Controlled Trial.” It is in the 5 June 2001 issue of Annals of Internal Medicine (volume 134, pages 1024-1032). The authors are MAM Rogers, D Small, DA Buchan, CA Butch, CM Stewart, BE Krenzer, and HL Husovsky.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoHome Monitoring Service Improves Mean Arterial Pressure in Patients with Essential Hypertension Mary A.M. Rogers , David Small , Debra A. Buchan , Carl A. Butch , Christine M. Stewart , Barbara E. Krenzer , and Harold L. Husovsky Metrics Cited bye-Patient Relations Eine Online-Umfrage zu “sexualmedizin.de” 5 June 2001Volume 134, Issue 11Page: I-9KeywordsBlood pressureExerciseHealth careHealth information technologyHypertensionMean arterial pressurePatientsPrimary hypertensionRenal diseasesStroke ePublished: 5 June 2001 Issue Published: 5 June 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...