tbuckley/cabot-search huggingface dataset:
SAPS 3—From evaluation of the patient to evaluation of the intensive care unit.Part 2: Development of a prognostic model for hospital mortality at ICU admission
Authors: Rui P. Moreno, Phillip G. H. Metnitz, Eduardo Almeida, Barbara Jordan, Peter Bauer, Ricardo Abizanda Campos, Gaetano lapichino, David Edbrooke, Maurizia Capuzzo, Jean-Roger Le Gall
Journal: Intensive Care Medicine (2006)
The ultra-low molecular weight heparin (ULMWH) semuloparin for prevention of venous thromboembolism (VTE) in patients with cancer receiving chemotherapy: SAVE ONCO study.
Authors: G. Agnelli, D. J. George, W. Fisher, A. K. Kakkar, M. R. Lassen, P. Mismetti, P. Mouret, U. Chaudhari, A. G. G. Turpie
Journal: Journal of Clinical Oncology (2011)

LBA9014 The full, final text of this abstract will be available in Part II of the 2011 Annual Meeting Proceedings, distributed onsite at the Meeting on June 4, 2011, and as a supplement to the June 20, 2011, issue of Journal of Clinical Oncology.
Influenza 1981 to 1982
Authors: W. R. Barclay
Journal: JAMA (1981)

Physicians, like farmers, find their responsibilities and work load seasonal in nature. As the fall and winter seasons approach, they bring with them outbreaks of influenza caused by one of the well-recognized virus strains and possibly by a new variant, against which previous vaccination or illness will have no protective effect. Patients commonly ask about the value of influenza vaccine and its complications and about their physician's personal biases on the subject. The Immunizations Practices Advisory Committee of the Public Health Service has issued a timely and informative statement about the influenza vaccine that is available for the 1981 to 1982 season.<sup>1</sup> The committee recommends that chronically ill children and adults older than 65 years be vaccinated, for they are at high risk of serious complications and even death from influenza infection. In the 1980 to 1981 season, no outbreaks of influenza B were recorded; the predominant strain was
Book Review Sexual Health, Volume 1: Psychological Foundations; Volume 2: Physical Foundations; Volume 3: Moral and Cultural Foundations; Volume 4: State-of-the-Art Treatments and Research (Praeger Perspectives: Sex, Love, and Psychology.) Edited by Mitchell S. Tepper and Annette Fuglsang Owens. 1762 pp. total, illustrated. Westport, CT, Praeger, 2007. $425. 978-0-275-98774-9 (Vol. 1 ISBN, 978-0-275-98775-6; Vol. 2 ISBN, 978-0-275-98776-3; Vol. 3 ISBN, 978-0-275-98777-0; Vol. 4 ISBN, 978-0-275-…
Authors: Sheryl A. Kingsberg
Journal: New England Journal of Medicine (2007)
Chemical Studies on the Components of Normal and Neoplastic Tissues III. The Composition and Amphoteric Properties of the Nucleoprotein Fraction of the Jensen Rat Sarcoma
Journal: JNCI Journal of the National Cancer Institute (1940)

Journal Article Chemical Studies on the Components of Normal and Neoplastic Tissues III. The Composition and Amphoteric Properties of the Nucleoprotein Fraction of the Jensen Rat Sarcoma Get access Jesse P. Greenstein, Jesse P. Greenstein research fellow National Cancer Institute, National Institute of Health, United States Public Health Service Search for other works by this author on: Oxford Academic PubMed Google Scholar J. W. Thompson, J. W. Thompson associate pharmacologist National Cancer Institute, National Institute of Health, United States Public Health Service Search for other works by this author on: Oxford Academic PubMed Google Scholar Wendell V. Jenrette Wendell V. Jenrette junior physiologist National Cancer Institute, National Institute of Health, United States Public Health Service Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 1, Issue 3, December 1940, Pages 367–376, https://doi.org/10.1093/jnci/1.3.367 Published: 01 December 1940
REPORTS OF OFFICERS
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Guidelines for the diagnosis of rheumatic fever. Jones Criteria, 1992 update. Special Writing Group of the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association
Authors: Adnan S. Dajani, Elia Ayoub, Fredrick Z. Bierman, Alan L. Bisno, Floyd W. Denny, David T. Durack, Patricia Ferrieri, Michael Freed, Michael Gerber, Edward L. Kaplan, Adolf W. Karchmer, Milton Markowitz, Shahbudin H. Rahimtoola, Stanford T. Shulman, Gene Stollerman, Masato Takahashi, Angelo Taranta, Kathryn A. Taubert, Walter Wilson, Durack, Durack
Journal: JAMA (1992)

The Jones Criteria for guidance in the diagnosis of acute rheumatic fever were first published by T. Duckett Jones, MD, in 1944 and have been revised over the years by the American Heart Association. The current guidelines are an update of these criteria. For the first time, the guidelines are designed to establish the initial attack of acute rheumatic fever. Major manifestations, minor manifestations, and supporting evidence of antecedent group A streptococcal infection are discussed. These updated guidelines expand on the available tools to diagnose streptococcal pharyngitis and clarify the available antibody tests for detecting antecedent group A streptococcal infection. At the present time echocardiography without accompanying auscultatory findings is insufficient to be the sole criterion for valvulitis in acute rheumatic fever. Finally, this article addresses overdiagnosis of rheumatic fever and lists exceptions to the Jones Criteria, including recurrent attacks in individuals with a history of rheumatic fever.
Fatal Pancreatitis after Endoscopic Balloon Dilation for Extraction of Common Bile Duct Stones in an 80-Year-Old Woman
Authors: J. García-Cano
Journal: Endoscopy (2006)

Some studies have reported that endoscopic balloon dilation (EBD) for extracting common bile duct stones is associated with higher complication rates in comparison with endoscopic sphincterotomy (EST) [1], although EBD has been found to be a safe method in other reports [2] [3]. However, it appears that EBD should be used with extreme caution in patients aged 50 years or younger [4], since in relatively young and healthy patients, the technique has been associated with increased rates of pancreatitis, leading even to death [5]. In this group of patients, the complication rate with EBD appears to be higher than with endoscopic biliary sphincterotomy. The morbidity associated with EBD is presumed to be due to edema or spasm caused by the trauma of dilation, which can lead to transient obstruction of the pancreatic duct and trigger the inflammation cascade of pancreatitis. This effect may be more pronounced in young patients, while older ones may have a less severe inflammatory response [6].
Blood Usage Reviews
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Highlights
Journal: JAMA (2014)

To provide recent estimates of obesity prevalence in the United States, Ogden and colleagues analyzed 2011-2012 National Health and Nutrition Examination Survey (NHANES) data.The authors report that 8.1% of infants and toddlers, 16.9% of 2-to 19-year-olds, and 34.9% of adults were obese in 2011-2012.Examination of NHANES data from 5 consecutive surveys revealed no significant changes in obesity prevalence between 2003 and 2012. Medical Home-Associated Quality, Use, and Costs 815The patient-centered medical home practice model is intended to improve health care quality and efficiency.Friedberg and colleagues assessed whether these goals are achieved in an analysis of claims data from 32 primary care practices participating in a pilot medical home intervention and 29 comparison practices of similar size, specialty, and location.The authors found that practices participating in the intervention adopted new structural capabilities such as chronic disease registries and received National Committee for Quality Assurance recognition; however, the intervention was associated with very limited improvements in quality and did not reduce hospital use or costs over 3 years.In an Editorial, Schwenk discusses focused implementation of the medical home practice model.
Atypical metastasis from prostate cancer. Clinical utility of the immunoperoxidase technique for prostate-specific antigen
Authors: D. T. Tell
Journal: JAMA (1985)

We review our experience with the immunoperoxidase technique of staining tissue for prostate-specific antigen in four patients with atypical metastases from prostate cancer. Our results indicate that this test is clinically useful for the diagnosis of metastatic prostate cancer in patients with an unsuspected primary prostate malignancy. Further, application of prostatic-specific antigen testing may confirm metastatic prostate cancer in atypical sites in patients with a previously diagnosed prostate malignancy. (<i>JAMA</i>1985;253:3574-3575)
Correction
Journal: The Lancet Infectious Diseases (2015)

ENCORE1 Study Group. Efficacy and safety of efavirenz 400 mg daily versus 600 mg daily: 96-week data from the randomised, double-blind, placebo-controlled, non-inferiority ENCORE1 study. Lancet Infect Dis 2015; published online April 13. http://dx.doi.org/10.1016/S1473- 3099(15)70060-5—In this Article, the numbers of patients in the 96-week adverse events analysis were incorrect.
MELANURIA
Authors: S. N. BLACKBERG
Journal: JAMA (1933)

Melanuria has been reported as occurring in a variety of apparently unrelated pathologic conditions, such as melanotic neoplasms, wasting diseases, intestinal obstruction, lobar pneumonia, pernicious anemia, extensive liver destruction, exposure to the sun's rays, and after roentgenologic treatment. The sum of these observations might easily give the impression that melanogen in the urine is not an uncommon finding. However, a survey of fifteen cases of melanotic malignant growths treated at the Presbyterian Hospital<sup>1</sup>during the past ten years revealed the fact that melanin was found in the urine of only four of these patients. It seemed incongruous that melanuria should be reported as occurring in so many conditions unassociated with necropsy evidence of pathologic melanin formation, whereas in those diseases in which the excessive production of melanotic pigment is a characteristic feature, melanuria was demonstrated in only about 25 per cent of the Presbyterian Hospital cases. The foregoing observations
Dialysis Therapy
Authors: Stephen Pastan, James Bailey
Journal: New England Journal of Medicine (1998)

The population with end-stage renal disease (ESRD) in the United States is composed of more than 200,000 patients who undergo dialysis and 70,000 patients with functioning kidney transplants.1 With the prevalence of ESRD growing at a rate between 7 and 9 percent per year, it is projected that there will be more than 350,000 such patients by the year 2010.2 Although the overall incidence of ESRD is 242 cases per million population per year, blacks have a disproportionately high incidence (758 per million population per year), as compared with whites (180 per million population per year).1 Diabetes is the leading . . .
Narcotic dependency in pregnancy. Methadone maintenance compared to use of street drugs
Authors: B. Stimmel
Journal: JAMA (1976)

The course of pregnancy and delivery in 28 women under closely supervised methadone maintenance (group 1) was compared with that of 57 women using heroin or methadone under less controlled circumstances (group 2) and with that of 30 women free of mood-altering medications (group 3). Women in group 1 had the lowest incidence of coexisting medical problems (<i>P</i>=.025), with an incidence of fetal distress not statistically different from that of women in group 3. Infants born to women in group 2 had the highest incidence of fetal distress (<sup>P</sup>&lt;.05), with four congenital defects, one stillbirth, and one neonatal death. Symptoms characteristic of narcotic withdrawal occurred with similar frequency in group 1 and 2 infants, appearing earlier in children whose mothers were users of heroin. These findings indicate that maintenance of the pregnant addict under closely supervised methadone therapy is compatible with an uneventful pregnancy and birth of a healthy infant whose withdrawal symptoms in the neonatal period are readily controllable. (<i>JAMA</i>235:1121-1124, 1976)
A T2* MRI Prospective Survey on Heart and Liver Iron In Thalassemia Major Patients Treated with Sequential Deferipron–Desferrioxamine versus Deferasirox
Authors: Alessia Pepe, Giuseppe Rossi, Antonella Meloni, Dell'Amico Maria Chiara, D'Ascola Domenico Giuseppe, Marcello Capra, Aldo Filosa, Paolo Cianciulli, Aurelio Maggio, Cristina Salvatori, Gennaro Restaino, Massimo Lombardi, Caterina Borgna-Pignatti
Journal: Blood (2010)
Correction: Physician Emigration from Sub-Saharan Africa to the United States: Analysis of the 2011 AMA Physician Masterfile
Authors: Akhenaten Benjamin Siankam Tankwanchi, ÃaÄlar Ãzden, Sten H. Vermund
Journal: PLoS Medicine (2013)

Background:The large-scale emigration of physicians from sub-Saharan Africa (SSA) to high-income nations is a serious development concern.Our objective was to determine current emigration trends of SSA physicians found in the physician workforce of the United States. Methods and Findings:We analyzed physician data from the World Health Organization (WHO) Global Health Workforce Statistics along with graduation and residency data from the 2011 American Medical Association Physician Masterfile (AMA-PM) on physicians trained or born in SSA countries who currently practice in the US.We estimated emigration proportions, year of US entry, years of practice before emigration, and length of time in the US.According to the 2011 AMA-PM, 10,819 physicians were born or trained in 28 SSA countries.Sixty-eight percent (n = 7,370) were SSA-trained, 20% (n = 2,126) were UStrained, and 12% (n = 1,323) were trained outside both SSA and the US.We estimated active physicians (age #70 years) to represent 96% (n = 10,377) of the total.Migration trends among SSA-trained physicians increased from 2002 to 2011 for all but one principal source country; the exception was South Africa whose physician migration to the US decreased by 8% ( 2156).The increase in last-decade migration was .50% in Nigeria (+1,113) and Ghana (+243), .100% in Ethiopia (+274), and .200%(+244) in Sudan.Liberia was the most affected by migration to the US with 77% (n = 175) of its estimated physicians in the 2011 AMA-PM.On average, SSA-trained physicians have been in the US for 18 years.They practiced for 6.5 years before US entry, and nearly half emigrated during the implementation years (1984)(1985)(1986)(1987)(1988)(1989)(1990)(1991)(1992)(1993)(1994)(1995)(1996)(1997)(1998)(1999) of the structural adjustment programs. Conclusion:Physician emigration from SSA to the US is increasing for most SSA source countries.Unless far-reaching policies are implemented by the US and SSA countries, the current emigration trends will persist, and the US will remain a leading destination for SSA physicians emigrating from the continent of greatest need.
Early-onset cyclophosphamide-induced interstitial pneumonitis
Authors: J. I. Spector
Journal: JAMA (1979)

This article describes three cases of biopsy-proved interstitial pneumonitis secondary to cyclophosphamide therapy. The pulmonary reactions developed after one to three courses of combination chemotherapy in three patients with diffuse histiocytic lymphoma. Resolution of the pulmonary infiltrates and blood gas value abnormalities followed discontinuation of use of this drug without recurrence when chemotherapy regimens excluding cyclophosphamide were subsequently used. Prednisone was given to all patients after the diagnosis was made, but its role in the resolution of the toxic changes is uncertain. The potential for early onset of cyclophosphamide-induced interstitial pneumonitis has not been previously stressed, but should lead to vigorous investigation of pulmonary reactions occurring at any time after initiation of therapy with this drug. (<i>JAMA</i>242:2852-2854, 1979)
Involvement of nitric oxide and prostaglandins in gastric mucosal hyperemia of portal-hypertensive anesthetized rats
Authors: M Casadevall
Journal: Hepatology (1993)

This study investigates the effects of inhibition of nitric oxide synthesis by NG-nitro-L-arginine methyl ester (L-NAME), the inhibition of prostaglandin synthesis with indomethacin and the combined effects on gastric mucosal hyperemia of ketamine-anesthetized rats with portal hypertension induced by partial portal vein ligation. The hydrogen gas–clearance technique was used for measurement of gastric mucosal blood flow. Blood pressure increased with L-NAME administration in a similar manner in portal-hypertensive and sham-operated rats. Low doses of L-NAME (1 and 3 mg/kg, intravenously) caused a significant and dosedependent reduction in gastric mucosal blood flow in portal-hypertensive rats but had no effect on shamoperated animals. With a higher dose of L-NAME (13 mg/kg, intravenously), a significant decrease in gastric mucosal blood flow was observed in both portal-hypertensive and sham-operated rats. Indomethacin pretreatment (5 mg/kg, subcutaneously) caused a significant decrease in basal gastric mucosal blood flow of portal-hypertensive rats but did not modify this parameter in sham-operated animals. In sham-operated rats pretreated with indomethacin, the lower dose of L-NAME (3 mg/kg) did not significantly modify basal gastric mucosal blood flow. Likewise, pretreatment with indomethacin in sham-operated rats did not augment the significant reduction in gastric mucosal blood flow produced by the higher dose of L-NAME. In portal-hypertensive rats the significant dose-dependent reduction in gastric mucosal blood flow induced by L-NAME (3 and 13 mg/kg) was not significantly altered by pretreatment with indomethacin. Portal pressure was higher in portal-hypertensive than in sham-operated rats, and no significant differences were observed in this parameter between portal-hypertensive animals treated with different doses of L-NAME. These results indicate that both nitric oxide and prostaglandins may be involved in the gastric mucosal hyperemia of portal-hypertensive rats. However, no synergistic interactions between these two endogenous vasodilators could be observed in this experimental model. (HEPATOLOGY 1993;18:628–634.)
"The impact of a lung cancer computed tomography screening result on smoking abstinence." C.M. van der Aalst, R.J. van Klaveren, K.A.M. van den Bergh, M.C. Willemsen and H.J. de Koning. Eur Respir J 2011; 37: 1466-1473.
Journal: European Respiratory Journal (2011)

We regret that errors appeared in table 1 and figure 1 of the above manuscript.Corrected copies of the table and figure are presented below, along with a description of the errors.TABLE 1 Baseline characteristics of the participants of the Dutch-Belgian Randomised Controlled Lung Cancer Screening Trial (NELSON trial) and the respondents of the subcohort# Male smokers randomised in the screening arm Smoking cessation questionnaire respondents Total Test negatives Test indeterminates Age yrs 58.0¡4.9 58.0¡5.0 57.9¡5.0 58.6¡4.9Level of education
Altered distribution and synthesis of laminin-5 (kalinin) in oral lichen planus, epithelial dysplasias and squamous cell carcinomas
Authors: T. KAINULAINEN, H. AUTIO-HARMAINEN, A. OIKARINEN, S. SALO, K. TRYGGVASON, T. SALO
Journal: British Journal of Dermatology (1997)

Laminin‐5 is a glycoprotein which mediates epithelial cell adhesion to the basement membrane. This study describes the distribution and synthesis of laminin‐5 in oral lichen planus, epithelial dysplasias, squamous cell carcinomas and a lymph node metastasis using immunohistochemistry and in situ hybridization. In normal oral mucosa and lichen planus, immunoreaction to the laminin‐5 was seen as a thin continuous, delicate line in the basement membrane region, although slight irregularities in the thickness and intensity of the immunoreaction could be detected in some cases with lichen planus. In epithelial dysplasias, the laminin‐5 staining was discontinuous and more diffuse compared to lichen planus and normal mucosa. The immunoreaction was generally extracellular, although in some cases with lichen planus and epithelial dysplasia there were a few basal epithelial cells showing cytoplasmic staining. The invasive carcinomas and the lymph node metastasis showed a striking, intense cytoplasmic, staining of the carcinoma cells along the invasive border of the neoplastic islands and in individual infiltrating carcinoma cells. Using in situ hybridization, the laminin‐5 γ2 chain mRNA expression could not be detected in normal oral mucosa whereas, in non‐dysplastic lichen planus and, more strongly, in dysplasias, there was a clear increase in the expression of laminin‐5 mRNA in the basal epithelial cells. The most intensive signal was detected in the invasive front of the oral squamous cell carcinomas and the lymph node metastasis. We conclude that, in oral squamous cell carcinoma, there is altered synthesis and secretion of laminin‐5 mRNA and protein. It is also evident that in dysplastic lesions of oral epithelium the synthesis and distribution of laminin‐5 is abnormal.