CORTISONE
Authors: E C KENDALL
Journal: Annals of Internal Medicine (1950)

Article1 October 1950CORTISONEEDWARD C. KENDALL, Ph.D.EDWARD C. KENDALL, Ph.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-4-787 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe name John Phillips has been remembered by the American College of Physicians on fourteen previous occasions. This afternoon I have been asked to give the fifteenth John Phillips Lecture, and at this time I wish to express my appreciation for the honor which has thus been conferred on me. Dr. Phillips spent his active life in the field of clinical medicine. It is my special pleasure to honor his memory by a report of the progress in clinical medicine which has been made possible by contributions from the field of biochemistry.During the past 20 years an unusual and...Bibliography1. ReichsteinShoppee TCW: The hormones of the adrenal cortex. In Harris, R. S., and Thimann, K. V.: Vitamins and hormones, 1943, Academic Press, Inc., Publishers, New York, vol. 1, pp. 345-413. Google Scholar2. Kendall EC: The influence of the adrenal cortex on the metabolism of water and electrolytes. In Harris, R. S., and Thimann, K. V.: Vitamins and hormones, 1948, Academic Press, Inc., Publishers, New York, vol. 6, pp. 277-327. Google Scholar3. Kendall EC: The chemistry and partial synthesis of adrenal steroids, New York Acad. Sc. 50: 540-547 (June) 1949. CrossrefMedlineGoogle Scholar4. SpragueGastineauMasonPower RGCFHLMH: Effects of synthetic 11-dehydrocorticosterone (compound A) in a subject with Addison's disease, Am. J. Med. 4: 175-185 (Feb.) 1948. CrossrefMedlineGoogle Scholar5. Sarett LH: Partial synthesis of pregnene-4-triol-17(β), 20(β), 21-dione-3, 11 and pregnene-4-diol-17(β), 21-trione-3,11, 20 monoacetate, J. Biol. Chem. 162: 601-631 (Mar.) 1946. CrossrefMedlineGoogle Scholar6. Sarett LH: A new method for the preparation of 17(α)-hydroxy-20-ketopregnanes, J. Am. Chem. Soc. 70: 1454-1458 (Apr.) 1948. CrossrefMedlineGoogle Scholar7. Hench PS: The potential reversibility of rheumatoid arthritis, Proc. Staff Meet., Mayo Clin. 24: 167-178 (Mar. 30) 1949. Google Scholar8. MattoxKendall VREC: Method for introduction of a double bond in 3-ketosteroids applied to the partial synthesis of adrenal cortical hormones. Abstracts of Papers, 115th Meeting American Chemical Society, San Francisco, March 27 to April 1, 1949, pp. 32L-33L. Google Scholar9. HenchKendallSlocumbPolley PSECCHHF: Effects of cortisone acetate and pituitary ACTH on rheumatoid arthritis, rheumatic fever and certain other conditions: a study in clinical physiology, Arch. Int. Med. 85: 545-666 (Apr.) 1950. CrossrefGoogle Scholar10. HenchKendallSlocumbPolley PSECCHHF: The effect of a hormone of the adrenal cortex (17-hydroxy-11-dehydrocorticosterone: compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis: preliminary report, Proc. Staff Meet., Mayo Clin. 24: 181-197 (Apr. 13) 1949. MedlineGoogle Scholar11. SpraguePowerMasonAlbertMathiesonHenchKendallSlocumbPolley RGMHHLADRPSECCHHF: Observations on the physiologic effects of cortisone and ACTH in man, Arch. Int. Med. 85: 199-258 (Feb.) 1950. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Presented as the John Phillips Memorial Lecture at the Thirty-first Annual Session of the American College of Physicians, Boston, Massachusetts, April 19, 1950. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThe management of glucocorticoid deficiency: Current and future perspectivesInvestigations of Glucocorticoid Action in GNThe History of Cortisone Discovery and DevelopmentCorticosteroids in Pediatric EndocrinologyDiagnosis and classification of Addison's disease (autoimmune adrenalitis)Historia de los glucocorticoidesAn historical review of rheumatoid arthritis treatment:1948 to 1952Cortisonbehandlung bei allergischem SchnupfenDie Ausscheidungen cortison�hnlicher Substanzen w�hrend Cyclus, Geburt und WochenbettTHE REVERSIBILITY OF CERTAIN RHEUMATIC AND NONRHEUMATIC CONDITIONS BY THE USE OF CORTISONE OR OF THE PITUITARY ADRENOCORTICOTROPIC HORMONE*PHILIP S. HENCH, M.D., F.A.C.P.Cortisone Therapy in Anterior-Segment Inflammation*Die Wirkungen der Therapie mit dem adrenocorticotropen Hypophysenhormon (ACTH) auf den Stoffwechsel 1 October 1950Volume 33, Issue 4Page: 787-796KeywordsBiochemistryMemory ePublished: 1 December 2008 Issue Published: 1 October 1950 Copyright & PermissionsCopyright, 1950, by The American College of PhysiciansPDF downloadLoading ...