tbuckley/cabot-search huggingface dataset:
Ulceration and Perforation of Intestine Due to Necrotizing Arteriolitis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A PLEA FOR CONCISENESS IN WRITING.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Highlights
Authors: Stephen Audio
Journal: JAMA (2018)

Comparison of Prosthetic Aortic Valves 27The mechanically expanded valve was designed to avoid malposition, paravalvular leak, and hemodynamic compromise during implantation.In a trial of 912 patients with severe aortic stenosis at high risk of mortality, Feldman and colleagues demonstrated that the mechanically expanded valve was not inferior to a self-expanding valve in safety or effi cacy.CME jamanetwork.com/learning
Pharyngeal Examination
Authors: A. L. Hovenden
Journal: CA A Cancer Journal for Clinicians (1981)

sible elevation of acid phosphataseâ€• after rectal exam should be laid to rest, how ever.Johnson et a!' found that rectal exam had no effect on tartrate labile acid phos phatase after either five minutes or 24 hoursâ€"whether the patient had BPH or cancer of the prostate.Bannerjee et al2 re ported that no significant change occurred in the formol-stable serum acid phospha tase in 200 patients with levels checked before and at intervals between five min utes and 48 hours after digital exam.
The contributions of authors to multiauthored biomedical research papers
Authors: D. W. Shapiro
Journal: JAMA (1994)

<h3>Objective.</h3> —To determine the contributions of each author to multiauthored biomedical research papers. <h3>Design.</h3> —Mailed, self-administered survey. <h3>Participants.</h3> —A total of 184 first authors from a consecutive sample of 200 papers with four or more authors published in 10 leading biomedical journals. <h3>Main Outcome Measures.</h3> —First authors' ratings of which authors had made substantial contributions to the following: initial conception of the study, design of the study, provision of needed resources, collection of data, analysis and interpretation of data, and writing the first draft of the paper or revising drafts for important intellectual content. <h3>Results.</h3> —The contributions of nonfirst authors varied greatly within and among papers. Even second and last authors—though they generally contributed more than other nonfirst authors—were markedly inconsistent in the extent and pattern of their contributions. Time spent on the research differed among authors by orders of magnitude. An appreciable number of authors made few or no substantial contributions to the research. <h3>Conclusions.</h3> —The nature and extent of contributions of nonfirst authors to biomedical research reported in multiauthored papers cannot reliably be discerned (or discounted) by authorship or order of authors. The two core purposes of scientific authorship—to confer credit and denote responsibility for research—are not adequately being met by these authorship practices. (<i>JAMA</i>. 1994;271:438-442)
Therapeutic uses of digoxin antibody
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
In the spotlight: Bioinstrumentation
Authors: Ken-ichi Yamakoshi
Journal: IEEE Reviews in Biomedical Engineering (2011)

The emergence and recent developments of the smart home have been briefly introduced in this review. Initial developments of smart homes comprised of computer-based housing to support elderly and challenged persons at home during daily living through the automatic monitoring of the usage of home infra structures. In light of the rapid growth of the aging society, which has created what might be regarded as a longevity crisis, healthcare is also one of the most serious and worldwide issues to address. From this background, the smart home with health care management has rapidly been pushed into the spotlight.
Proof-of-concept use of machine learning to predict tumor recurrence of early-stage hepatocellular carcinoma before therapy using baseline magnetic resonance imaging
Authors: Ahmet Said Kücükkaya, Tal Zeevi, Rajiv Raju, Nathan Chai, Stefan Haider, Mohamed Elbanan, Alexandra Petukhova, Mingde Lin, John Onofrey, Michal Nowak, Kirsten Cooper, Elizabeth Thomas, Bernhard Gebauer, David Madoff, Lawrence Staib, Ramesh Batra, Julius Chapiro
Journal: Journal of Hepatology (2020)
Risk of Coronary Heart Disease and Mortality for Adults With Subclinical Hypothyroidism
Authors: Noboru Takamura, Naomi Hayashida, Takahiro Maeda
Journal: JAMA (2010)

Rodondi et al. assessed the risk of coronary heart disease (CHD) and total mortality for adults with subclinical hypothyroidism. 1 In this study, they showed that the hazard ratio for CHD events was 1.00 (95% confidence interval [CI], 0.86-1.18)for a thyroid-stimulating hormone (TSH) level of 4.5 to 6.9 mIU/L, 1.17 (95% CI, 0.96-1.43)for a TSH level of 7.0 to 9.9 mIU/L, and 1.89 (95% CI, 1.28-2.80)for a TSH level of 10.0 to 19.9 mIU/L.They concluded that subclinical hypothyroidism is associated with an increased risk of CHD events and CHD mortality in those with higher TSH levels, particularly in those with a TSH concentration of 10 mIU/L or greater, and that minimal TSH elevations are not associated with an increased risk of CHD events and CHD mortality.On the other hand, they did not verify the CHD events and CHD mortality among those within the reference range of TSH levels.
Geophagia
Authors: R. G. Schipf
Journal: JAMA (1964)

<h3>To the Editor:—</h3> The report by Drs. Mengel and Carter (<i>JAMA</i><b>187</b>:955 [March 21] 1964) concerning geophagia is interesting to this geologist who once had the chance to discuss "clay eating" with an old Negro woman in North Carolina. The woman found me examining a road cut, and said the ground had "good eatin' clay." Although Mengel and Carter report that "good" clay is not gritty, my counselor insisted that the clay bed under discussion was good because it had "just the right amount of grit." When asked if clay eating had any bad effects, she replied that her daughter "always eats lots of clay and if it was bad, she'd be dead a long time ago."
TYPHOID FEVER AMONG PLUMBERS,
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis
Authors: Celine Hernandez, Peter Huebener, Jean-Philippe Pradere, Daniel J. Antoine, Richard A. Friedman, Robert F. Schwabe
Journal: Journal of Clinical Investigation (2019)

of Liverpool had data integrity concerns regarding the mass spectrometry data contributed by Daniel J. Antoine, shown in Figures 3B and 5A of this paper.The authors have also identified errors in the figure labels for Figures 5H and 6D.The authors have provided a corrected version of this article and a description of changes below.In our published work, we reported that hepatocyte-derived HMGB1 links cell death to progenitor responses and hepatocarcinogenesis in chronic liver disease (CLD).We based our conclusions on extensive animal studies, including models of chemically or genetically induced chronic cell death in mice with liver-specific knockouts of HMGB1.While hepatocyte-specific deletion of HMGB1 did not significantly alter hepatic injury levels, inflammation, fibrosis, and regeneration, it reduced hepatocyte metaplasia and ductular/progenitor expansion.Passively released HMGB1 promoted ductular reaction in a nonautonomous fashion through RAGE, but not TLR4 or TLR9, as demonstrated by in vivo studies in mice harboring global receptor knockout and further confirmed by in vitro studies using a bipotential liver progenitor cell line.Mice with liver-specific deletion of HMGB1 displayed reduced HCC development in 3 models of chronic hepatocellular death, but not in a model lacking chronic liver injury, further supporting the role of HMGB1 as a DAMP.Similarly to what we observed for CLD, we found that HMGB1 promoted a progenitor signature within tumors, a key feature of HCC aggressiveness.
THE DIABETIC CHILD
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ingestion, Inhalation, and Dermal Exposures to Chloroform and Trichloroethene from Tap Water
Authors: Clifford P. Weisel, Wan-Kuen Jo
Journal: Environmental Health Perspectives (1996)

Individuals are exposed to volatile compounds present in tap water by ingestion, inhalation, and dermal absorption. Traditional risk assessments for water often only consider ingestion exposure to toxic chemicals, even though showering has been shown to increase the body burden of certain chemicals due to inhalation exposure and dermal absorption. We collected and analyzed time-series samples of expired alveolar breath to evaluate changes in concentrations of volatile organic compounds being expired, which reflects the rate of change in the bloodstream due to expiration, metabolism, and absorption into tissues. Analysis of chloroform and trichloethene in expired breath, compounds regulated in water, was also used to determine uptake from tap water by each route (inhalation, ingestion, or absorption). Each route of exposure contributed to the total exposure of these compounds from daily water use. Further, the ingestion dose was completely metabolized before entering the bloodstream, whereas the dose from the other routes was dispersed throughout the body. Thus, differences in potential biologically effective doses depend on route, target organ, and whether the contaminant or metabolite is the biologically active agent.
MBCL-13. CORRELATION OF HISTOPATHOLOGY, CHROMOSOMAL MICROARRAY, AND NANOSTRING BASED 22-GENE ASSAY FOR MEDULLOBLASTOMA SUBGROUP ASSIGNMENT ON “HEAD START” 4 CLINICAL TRIAL
Authors: Girish Dhall, Parth Patel, Megan Blue, Jaclyn Biegel, Isabel Almiraz-Suarez, Eugene Hwang, Christopher Pierson, Daniel Boue, Jonathan Finlay
Journal: Neuro-Oncology (2020)

Abstract “Head Start” 4 (HS 4) is a prospective randomized clinical trial that tailors treatment based on medulloblastoma molecular subgroups and response to induction chemotherapy to compare efficacy of one versus three (tandem) cycles of myeloablative chemotherapy. Advances in RNA and DNA profiling have identified four molecular subgroups of medulloblastoma with prognostic significance: Sonic Hedgehog (SHH) subtype, WNT subtype, Group 3, and Group 4. In HS 4 trial, we utilize a combination of histopathology and immunohistochemistry (pathology/IHC), as well as chromosomal microarray analysis (CMA) utilizing OncoScanTM (Thermo Fisher) to classify medulloblastoma samples into either SHH, WNT, or non-WNT/non-SHH (Group 3/4) subgroups at the time of diagnosis. NanoString based 22-gene assay is performed retrospectively to test concordance. We have pathology/IHC, CMA, and NanoString data on 26 infants and young children with medulloblastoma enrolled on HS 4. Pathology/IHC was able to assign samples to SHH, WNT, and non-WNT/non-SHH subgroups in all but two cases: one case was classified as Group 3, and the second as SHH by both CMA and NanoString. CMA was indeterminate in six cases, of which, pathology/IHC was able to assign all six samples aforementioned three subgroups. NanoString was indeterminate in two cases: one case was classified as SHH by CMA and pathology/IHC, and the second case was indeterminate by CMA but was assigned as non-WNT/non-SHH on pathology/IHC. There is excellent correlation between NanoString and combination of histopathology and CMA for core medulloblastoma subgrouping on HS 4. Methylation studies are ongoing.
Serial hemodynamic measurements in well-differentiated hepatocellular carcinomas
Authors: S SAITOH
Journal: Hepatology (1995)

We performed serial hemodynamics in 15 patients with 21 well-differentiated hepatocellular carcinomas. The total length of the observation period ranged from 129 to 678 days (median, 368). We investigated both arterial and portal blood flow at intervals of at least 4 months. Arterial blood flow was measured with carbon dioxide—enhanced ultrasonography (US), and portal blood flow was measured with computed tomographic arterial portography (CTAP). None of the tumors were hypervascular on the initial study; however, by the final study nine nodules (42.9%) had become homogeneously hypervascular, two (9.5%) had become partially hypervascular, and the others did not change. Of 10 nodules without portal blood supply on any study, 8 became hypervascular by the final study. Of 11 nodules with portal blood supply on the initial study, a follow-up study showed no change in portal flow in 6 and the loss of portal flow in 5. Four of these five became hypervascular, with a documented loss of portal flow before the increase in arterial flow. The doubling time of tumors with a homogeneous increase in arterial blood flow ranged from 89 to 333 days (median, 172), whereas the doubling time of other tumors ranged from 227 to 607 days (median, 392). Thus, growth rate and vascularity in well-differentiated hepatocellular carcinoma are closely correlated. When the well-differentiated hepatocellular carcinoma has portal blood flow and is not hypervascular, it grows slowly. On the other hand, when it loses portal blood flow and becomes hypervascular, it grows rapidly.
Die Lagereflexe des Menschen. Klinische Untersuchungen über Haltungs- und Stellreflexe und verwandte Phänomene.
Journal: JAMA (1928)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fetal alcohol syndrome. Experience with 41 patients
Authors: J. W. Hanson
Journal: JAMA (1976)

Forty-one patients with the fetal alcohol syndrome, including 11 whose cases were previously reported, were studied. These children have a pattern of defects including prenatal and postnatal growth deficiency, small head size with mental subnormality, and facial abnormalities allowing for recognition of the disorder in infancy. The same pattern of abnormalities has been independently reported from France in a series of 127 offspring of chronic alcoholics. (<i>JAMA</i>235:1458-1460, 1976)
Problems in the staging of Hodgkin disease
Authors: Peter C. Raich
Journal: JAMA (1973)

<h3>To the Editor.—</h3> I agree in principle with Smith et al (224:1026, 1973) that a staging laparotomy may not be needed in all patients with Hodgkin disease, especially in those patients with stage I and II-A disease with favorable histology. To classify a patient as having clinical stage IV disease, however, on the basis of abnormal liver function studies or hepatomegaly, as was done by the authors preoperatively in four patients, is possibly a serious error. This has been demonstrated quite decisively by several studies, including those by Ultman<sup>1</sup>and Givler et al.<sup>2</sup>Ultman reported. liver biopsy studies on 120 patients who clinically had no evidence of liver involvement, four of whom were found to have Hodgkin disease in the liver. Thirty-two patients were thought to have liver involvement clinically; only three had positive liver biopsies on laparotomy. To avoid confusion in such patients it would be more
CULTIVATION OF A FILTRABLE ORGANISM FROM THE NASOPHARYNGEAL WASHINGS IN INFLUENZA
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal