tbuckley/cabot-search huggingface dataset:
Contents: (Adv. Healthcare Mater. 3/2016)
Journal: Advanced Healthcare Materials (2016)

Advanced Materials has been bringing you the best in materials research for over twenty-five years.With its increased ISI Impact Factor of 17.493, Advanced Materials is one of the most influential journals in the field.Publishing every week, Advanced Materials now brings you even more of the latest results at the cutting edge of materials science. www.advmat.de Controlled Release"On-demand" release of genetic material for regulation of cell gene expression to control cell behavior is an innovative strategy for disease therapeutics and tissue regeneration.On page 305, E. Alsberg and co-workers explore a photolabile hydrogel system that can be used to actively tune the release of siRNA via the application of external UV light.The cover image illustrates how external UV light drives hydrogel degradation, and this accelerates the release of siRNA to ultimately alter gene expression of recipient cells.
Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells
Authors: Anna M. Schulz, Susanne Stutte, Sebastian Hogl, Nancy Luckashenak, Diana Dudziak, Céline Leroy, Ignasi Forné, Axel Imhof, Stephan A. Müller, Cord H. Brakebusch, Stefan F. Lichtenthaler, Thomas Brocker
Journal: The Journal of Experimental Medicine (2015)
Breathe
Authors: C. Alessandra Colaianni, Kim Knoper, Natalie Koscal
Journal: New England Journal of Medicine (2021)

It's Dr. C.'s first weekend taking call at her new hospital, only weeks after graduating from residency. Called in to "level" a patient with laryngeal cancer and a closing airway, she's suddenly disorientingly aware that she's in charge now. Does she have what it takes?
Protein conjugate pneumococcal vaccines
Journal: BMJ (2002)

tion strategies. 16Over the 12 months after randomisation, the total cost of consultations, referrals, investigations, and treatment was on average £404.31 in the endoscopy group compared with only £205.67 in the non-invasive H pylori testing group.Two smaller studies have compared H pylori testing with endoscopy in subgroups of patients with dyspepsia referred for endoscopy. 4 6No differences were found between the two investigation strategies with respect to resolution of dyspepsia, use of drugs, or visits to the general practitioner.Use of endoscopy was reduced by 83% over the two year follow up.
Coordination of Intrinsic, Extrinsic and Endoplasmic Reticulum-Mediated Apoptosis by Imatinib Mesylate Combined with Arsenic Trioxide in Chronic Myeloid Leukemia.
Authors: Ji Zhang, Yanzhi Du, Kankan Wang, Hai Fang, Junmin Li, Dakai Xiao, Peizheng Zheng, Yulong Chen, Huiyong Fan, Qinghua Zhang, Jing Fang, Charles Auffray, Saijuan Chen, Zhu Chen, Ji Zhang
Journal: Blood (2005)
BOOK REVIEWS
Authors: M. A. WEINER
Journal: JNCI Journal of the National Cancer Institute (1989)

Journal Article BOOK REVIEWS Get access Hodgkin's Disease in Children: Controversies and Current Practice. W. A. Kamps, G. B. Humphrey, S. Poppema, eds. Dordrecht, The Netherlands: Kluwer Academic Publishers, 1989, 334 pp. $110. MICHAEL A. WEINER MICHAEL A. WEINER Tomorrows Children's Institute One Link South30 Prospect Ave. Hackensack, NJ 07601 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 81, Issue 15, 2 August 1989, Pages 1186–1187, https://doi.org/10.1093/jnci/81.15.1186-a Published: 02 August 1989
Errors in the Results Section of the Abstract
Journal: JAMA Network Open (2021)

Antonio Caycedo-Marulanda, MD, MSc; Lawrence Lee, MD, PhD; Sami A. Chadi, MD, MSc; Chris P. Verschoor, PhD; Jordan Crosina, MD; Shady Ashamalla, MD, MSc; Carl J. Brown, MD, MSc; Canadian taTME Expert Collaboration
Carvedilol increases plasma vascular endothelial growth factor (VEGF) in patients with chronic heart failure Rudolf A. De Boer, Hans-Marc J. Siebelink, Rene A. Tio, Dirk J. Van Veldhuisen. University Hospital, Thoraxcenter, Department of Cardiology, Groningen, The Netherlands
Journal: Journal of the American College of Cardiology (2001)
Modern Medicine. Its Theory and Practice in Original Contributions by American and Foreign Authors. Volume I. Bacterial Diseases— Non-Bacterial Fungus Infections—The Mycoses.
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Enhancing safety and delivery of oral chemotherapy utilizing lean methodology.
Authors: Debbie Fernandez, Kathy Hulen, Leigh Anne Scott, Kelsey Bambara, Gayle Creamer, Jeff Wright, Terry Tsue, Adam Neiberger, Marc Steven Hoffmann
Journal: Journal of Clinical Oncology (2018)

266 Background: An oral chemotherapy safety event prompted analysis of related workflows utilizing lean quality improvement methodology. This analysis identified high variation in prescription processing, lack of standardized safety checks, inefficient use of pharmacy time, and inadequate data collection. Our goal was to create an oral chemotherapy protocol that could ensure patients have the right oral chemotherapy agent, at the right dose, at the right time, with independent and efficient safety checks by nursing, pharmacy, and providers. Methods: Multidisciplinary teams participated in two kaizen workshops. utilizing lean methodology. Primary workshop objectives were (1) develop safety standards for oral chemotherapy similar to those for intravenous chemotherapy; (2) make workflows more efficient; and (3) have workflows that enable data collection and process control. The first workshop standardized oral chemotherapy prescription processing though a single workflow in the EMR. This enabled robust data collection and established a platform for safety interventions. The second workshop developed standardized safety checks for and integrated those into the EMR workflow. Given the rarity of serious safety events, a validation measurement was not feasible to track in 30-day PDCA cycles. Consequently, surrogate measures of utilization of the EMR prescribing algorithm and reduction of non-clinical pharmacy interventions were used to assess progress. Safety data were collected and correlated to surrogate outcomes for long-term impact assessment. Results: Interventions resulted in the following outcomes: 100% reduction in oral chemotherapy order defects reaching pharmacy; 97% improvement processing oral chemotherapy though a single EMR workflow; 23% reduction in oral chemotherapy processing time; In spite of a 51% increase in oral chemotherapy volume, no serious safety events have occurred in the last year. Conclusions: Comprehensive quality improvement in our oral chemotherapy process increased safety and efficiency while developing data collection systems for continuous improvement. Multidisciplinary workshops with key stakeholders using established lean methodology were critical to success.
The Blight and the Plight
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Liquid protein diets and torsade de pointes
Authors: B. N. Singh
Journal: JAMA (1978)

Three women, aged 27, 33, and 35 years, experienced recurrent syncope five months after losing 36 to 41 kg using liquid protein diets. No abnormalities were noted during physical examination except in one who was hypothyroid. Serum potassium levels varied between 2.9 and 3.9 mEq /liter. The ECGs demonstrated prominent U waves, QU<sub>c</sub>prolongation, and ST and T wave abnormalities, with left axis deviation in two patients. Syncopal episodes were due to ventricular tachycardia and fibrillation, which were not responsive to conventional antiarrhythmic agents used in two patients. Patients using liquid protein diets may thus experience reversible QU<sub>c</sub>prolongation giving rise to serious arrhythmias that are probably best treated with drugs that shorten the QT<sub>c</sub>interval. Caution should be exercised in the use of liquid protein diets for weight reduction in obesity. (<i>JAMA</i>240:115-119, 1978)
Biomaterial-centered sepsis and the total artificial heart. Microbial adhesion vs tissue integration
Authors: A. G. Gristina
Journal: JAMA (1988)

The principal barrier to the extended use of the total artificial heart is infection that is centered on the biomaterial constituting the prosthetic device and exacerbated by the surrounding damaged tissue. Ultrastructural studies of total artificial hearts removed from two patients indicate a failure of true tissue integration and diffuse, adhesive bacterial colonization of biomaterial surfaces. Biomaterials are, in part, susceptible to infection because, at the present state of the art, they are usually not well integrated with host tissue or, if hemodynamic, not optimally biocompatible or antiadhesive. (<i>JAMA</i>1988;259:870-874)
Adolescent Medicine
Authors: Jonathan D. Klein
Journal: JAMA (1993)

Two health care policy areas precipitated by the political events of 1992 will have major impact on adolescents. The first, the proposed health care reform, will likely affect adolescents' access to health care and may change our country's approach to reproductive health issues and to human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) prevention. Second, comprehensive Guidelines for Adolescent Preventive Services (GAPS) were developed to establish multispecialty, interdisciplinary guidelines for a package of clinical preventive services addressing both the traditional physical problems as well as the behavioral and emotional problems experienced by today's youth. GAPS advocates a major expansion of the role of primary care health providers in health promotion and in the prevention of adolescent morbidity and mortality. The potential for optimizing adolescents' physical, psychological, and social health status, and our ability to provide necessary services toward these goals are highly dependent on the political climate. Adolescents' access to care, the
&lt;TITLE&gt;Feeding your newborn&lt;/TITLE&gt;
Journal: JAMA (2000)

Feeding your newbornThe JAMA Patient Page is a public service of JAMA and the AMA.The information and recommendations appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis.ForThe JAMA Patient Page is a public service of JAMA and the AMA.The information and recommendations appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis.ForThe JAMA Patient Page is a public service of JAMA and the AMA.The information and recommendations specific information concerning your personal medical condition, JAMA and the AMA suggest that you consult your appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis.For specific information concerning your personal medical condition, JAMA and the AMA suggest that you consult your appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis.For physician.This page may be reproduced noncommercially by physicians and other health care professionals to share specific information concerning your personal medical condition, JAMA and the AMA suggest that you consult your physician.This page may be reproduced noncommercially by physicians and other health care professionals to share specific information concerning your personal medical condition, JAMA and the AMA suggest that you consult your with patients.Any other reproduction is subject to AMA approval.To purchase bulk reprints, call 212/354-0050.physician.This page may be reproduced noncommercially by physicians and other health care professionals to share with patients.Any other reproduction is subject to AMA approval.To purchase bulk reprints, call 212/354-0050.
'Uncle George' Resurrected
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Multiparametric Magnetic Resonance Imaging for the Detection of Clinically Significant Prostate Cancer: What Urologists Need to Know. Part 3: Targeted Biopsy
Authors: Wulphert Venderink, Joyce G. Bomers, Christiaan G. Overduin, Anwar R. Padhani, Gijs R. de Lauw, Michiel J. Sedelaar, Jelle O. Barentsz
Journal: European Urology (2019)

After a lesion has been assessed adequately on multiparametric magnetic resonance imaging (mpMRI), magnetic resonance (MR)-guided biopsy (MRGB) is the logical next step. The choice of the MRGB technique, however, is difficult.To show the advantages and disadvantages of the three commonly used MRGB techniques-MRI-ultrasound fusion MRGB (fus-MRGB), direct in-bore MRGB (inbore-MRGB), and cognitive MRGB (cog-MRGB), and to determine when each of the techniques can be used.Based on expert opinion and literature overview, the advantages, disadvantages, and challenges of fus-MRGB, inbore-MRGB, and cog-MRGB are evaluated. Further, the clinical setting of each biopsy strategy is assessed.Based on expert opinion and literature data, the three biopsy procedures are evaluated, and the important pros and cons are determined.The basic concept of each biopsy technique is reviewed, which would result in a clinical recommendation. This will be shown in individual patients.The accompanying video shows how fus-MRGB and inbore-MRGB are performed in our hospital. An important advantage of fus-MRGB is its generally availability; however, it has fusion-error limitations. Although not supported by evidence, inbore-MRGB seems to be better suited for smaller lesions, but is rather expensive. Cog-MRGB is easy to use and inexpensive, but is more operator dependent as it requires knowledge about both ultrasound and MR images. Readers should be aware that our MRGB approach is largely based on expert opinion and, where possible, supported by evidence.This article and the accompanying video show different MRGB techniques. The advantages and disadvantages of the three biopsy techniques, as well as the clinical setting in which each biopsy strategy is being used in our hospital, are discussed. Fus-MRGB is our first choice for prostate biopsy. Direct inbore-MRGB is used in difficult lesions but is mainly used as a "problem solver" (eg, a negative biopsy with a high suspicion for clinically significant prostate cancer). In our opinion, cog-MRGB is best for sampling larger and diffuse lesions.This third surgery in motion contribution shows our approach in magnetic resonance (MR)-guided biopsy (MRGB). Fusion MRGB is our first choice for prostate biopsy. In-bore MRGB is used in selected, difficult cases, mainly as a problem solver. In our point of view, cognitive MRGB seems to be best for sampling larger lesions and diffuse processes.
THE USE OF A MYDRIATIC AFTER THE AGE OF FORTY-FIVE.
Authors: HORACE M. STARKEY
Journal: JAMA (1903)

<h3>THE THEORY AND PRACTICE OF PROMINENT OPHTHALMOLOGISTS.</h3> In the letters sent out the following questions were asked: 1. What is your practice in regard to the use of mydriatics or cycloplegics in refraction work in patients beyond 45 years? 2. If they are used frequently, what advantages and what disadvantages or dangers, if any, do you find in such use? 3. If they are used infrequently or not at all is their omission due to disbelief in their utility or to fear of bad effect? 4. Is the belief in these advantages and disadvantages theoretical or the result of your own experience? 5. Can you cite cases in your own practice in which glaucoma has seemed to be caused or aggravated by the use of these drugs? Ninety of the 100 to whom letters were sent replied. These replies are classified as well as may be according to the
Rheumatology
Authors: William J. Koopman
Journal: JAMA (1991)

The most prevalent form of arthritis, osteoarthritis (OA), is characterized by progressive disintegration of articular cartilage, generally accompanied by new bone formation at joint margins and beneath involved cartilage. In some cases, the disease is a clear sequel to environmental insults (eg, posttraumatic OA) or metabolic disorders (eg, ochronosis), but, more commonly, the underlying origin is not apparent (primary OA). Efforts to identify inherited structural abnormalities in cartilage as a basis for primary OA have been prompted by impressive advances in molecular characterization of the structural components of cartilage coupled with evidence of familial forms of the disease. Pursuing this approach, Knowlton and colleagues<sup>1</sup>studied a family with multiple cases of precocious primary OA associated with mild chondrodysplasia. Ten members of the family, encompassing three generations, exhibited the disease. Using a labeled DNA fragment containing the type II procollagen gene, genomic DNA from multiple family members was examined for
THE MENSTRUAL FEVER OF CONSUMPTIVES.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Head to head comparison of liver stiffness measurement using transient elastography, 2D-shear wave elastography and magnetic resonance elastography for non-invasive evaluation of clinical significant portal hypertension
Authors: Filipe Andrade, Philippe Garteiser, Maxime Ronot, Laure Elkrief, Riccardo Sartoris, Marco Dioguardi Burgio, Magaly Zappa, Olivier Roux, Payance Audrey, Clement Lejealle, Didier Lebrec, Mohamed Bouattour, Olivier Soubrane, Dominique Valla, François Durand, Valérie Vilgrain, Castera Laurent, Bernard Van Beers, Pierre-Emmanuel Rautou
Journal: Journal of Hepatology (2020)
The Shrinking Man
Authors: Mayer L. Horensten
Journal: JAMA (1980)

A 37-year-old man, who had been undergoing hemodialysis for nine years, had severe osteodystrophy with a consequent 28-cm loss in height. This shrinkage in size is probably secondary to tertiary hyperparathyroidism. In spite of two previous explorations, there is still evidence of hyperparathyroidism and his present condition precludes surgical intervention. (<i>JAMA</i>244:267-268, 1980)
LETTER FROM NEW YORK.
Authors: None P. B. P.
Journal: JAMA (1891)

present under observation. All the remaining 36 could be set down as completely cured; and of these, 27 had one injection, 4 had two injections, and 5 had three injections. In no case did sloughing occur, and not one of the patients lost more than 24 hours from business. In the case of laboring men he generally made the injection on Saturday afternoon, so that the patient could go to his work, as usual, on Monday morning. From his experience he had reached the following conclusions: Carbolic injection is a safe method for the cure of hydrocele. It is practically painless. The patient can attend to business without more than one day's delay. The disagreeable effects of an anæsthetic are avoided. In the discussion on the paper Dr. John Murphy spoke of a case he had seen in which he believed that fatal carbolic poisoning resulted from injection of a
Chorionic gonadotropin in weight control. A double-blind crossover study
Authors: R. L. Young
Journal: JAMA (1976)

Two hundred two patients participated in a double-blind random crossover study of the effectiveness of human chorionic gonadotropin (HCG) vs placebo in a weight reduction program. Serial measurements were made of weight, skin-fold thickness, dropout rates, reasons for dropping out, and patient subjective response. There was no statistically significant difference between those receiving HCG vs placebo during any phase of this study (<i>P</i>&gt;.1). (<i>JAMA</i>236:2495-2497, 1976)