tbuckley/cabot-search huggingface dataset:
PTH-098 Are Outcomes Following Laparoscopic Resection for Inflammatory Bowel Disease in Adults and Children Comparable?
Authors: S Vickramarajah, C M McMullin, J Morton, M Brennan, C Salvestrini, F Torrente, R Heuschkel, R J Davies
Journal: Gut (2013)

<h3>Introduction</h3> Inflammatory bowel disease (IBD) has prevalence in Europe of approximately 2.2 million, with evidence of increasing incidence in the paediatric population. Up to 40% of patients will require surgery for their disease, the majority within the first year of diagnosis. Since 2007, a single surgeon whose main practise is in adults has performed laparoscopic resectional surgery for IBD in adults and children within separate dedicated adult and paediatric IBD multidisciplinary teams in a tertiary referral centre. Our aim was to assess short-term outcomes for adults and children following laparoscopic resectional surgery for IBD. <h3>Methods</h3> Analysis of a prospectively collected database was carried out to include all patients who had undergone a laparoscopic resection for IBD (excluding stoma formation alone and ileoanal pouch surgery) under the care of one surgeon between December 2007 and July2012. <h3>Results</h3> Fifty-nine patients underwent laparoscopic resections (28 children and 31 adults). Median age for children was 14 years (range 8–16 years) and adults 32 years (range 21–63 years). The median BMI for adults was 23 (range 18–38) and 19.5 for children (range 13–29.5). Operative times for adults and children were similar with a median of 210 and 165 minutes respectively (<i>p</i> =<i> 0.09</i>). Postoperative complication rates were not significantly different: 6 (19%) in the adult population and 4 (14%) in children (<i>p</i> =<i> 0.73</i>). There was 1 anastomotic leak (in the adult group). Median length of stay was 5 days in adults vs 6 days in children (<i>p</i> =<i> 0.09</i>). <h3>Conclusion</h3> Laparoscopic surgery in children is safe when performed by an experienced surgeon whose normal practise is in adults, with acceptable outcomes when compared to adults. <h3>Disclosure of Interest</h3> None Declared.
Evaluation of an oral contraceptive. Ethynodiol diacetate with mestranol (Ovulen)
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prognostic Implications of Elevated Creatine Kinase After Coronary Angioplasty
Authors: J. Aaron Herschfus
Journal: JAMA (1997)

<h3>To the Editor.</h3> —Dr Kong and colleagues<sup>1</sup>reported that elevation of CK following elective coronary artery intervention is associated with increased late cardiac mortality.<sup>1</sup>Earlier reports of placebo-controlled animal studies with pretreatment with coenzyme Q<sub>10</sub>(CoQ<sub>10</sub>)<sup>2,3</sup>found that the animals pretreated with CoQ<sub>10</sub>had less ischemia-reperfusion cardiac injury. They showed less myocardial tissue injury and lower CK and malondialdehyde release.
Caduceus
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Megavitamin Therapy
Authors: Linus Pauling
Journal: JAMA (1976)

<h3>To the Editor.—</h3> In the letter by Thomas H. Jukes (234:806, 1975) there is the statement "I did indeed mention Pauling's name in close context with the National Health Federation, but this association is tangible. Pauling appeared on behalf of the National Health Federation at the hearings that I attended on Bill S2801 before Senator Kennedy on Aug 14, 1974." I am not a member of the National Health Federation, and I did not appear on behalf of the National Health Federation at these hearings. I paid my own expenses in going to Washington to testify at the hearings. I had, together with Prof Roger J. Williams, filed suit against the Food and Drug Administration because of their regulations restricting the sale of vitamin C and other vitamins. The National Health Federation and other organizations also filed suits, and by court order the various suits were combined. I testified before Senator
Minoxidil
Authors: STUART L. LINAS
Journal: Annals of Internal Medicine (1981)

Minoxidil is an orally active vasodilator for treatment of severe hypertension. In combination with diuretics and beta-adrenergic blocking agents, it is effective treatment for more than 80% of patients whose blood pressure has been inadequately controlled with combinations of other antihypertensive drugs. Major adverse reactions include reflex activation of the adrenergic nervous system, renal sodium retention, and hypertrichosis. Despite the possibility of adverse reactions, minoxidil is indicated in patients whose blood pressure cannot be controlled with conventional therapy, in persons with major adverse reactions to other drugs, and in patients who are candidates for bilateral nephrectomy for control of hypertension.
Direct magnification lymphography
Authors: T. Ditchek
Journal: JAMA (1967)

Lymphography has j gained widespread acceptance as a method of diagnosing disease in abdominal and pelvic lymph nodes. However, the diagnostic accuracy of this procedure in neoplastic disease leaves much to be desired. Recent publications<sup>1,2</sup>have emphasized that a positive lymphographic diagnosis of neoplasm in the nodes may be confirmed histologically by 85% to 90% of cases. In cases with lymphograms not demonstrating neoplastic abnormalities, histologic examination will concur in only 65%. With regard to "false-positive" interpretations, normal variations in nodal architecture and fatty or fibrous filling defects may be misinterpreted.<sup>3</sup>With regard to "falsenegative" findings, actual neoplastic deposits in nodes may be too small for reliable detection. Because of these limitations, it was felt that a magnification technique would yield better definition of lymph node structure. Photographic enlargement of conventional x-ray films, however, fails to accomplish this because of the accompanying enlargement of penumbra effect and motion
ACTINOMYCOSIS TREATED WITH METHYLENE BLUE AND ROENTGEN RAY
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mrs Rodell
Authors: Adria Burrows
Journal: JAMA (1989)

People often ask me why I chose ophthalmology as my specialty. I state the reason quite simply: "Mrs Rodell." I met Mrs Rodell when I was in medical school. I had wanted to earn some extra money; perusing the ads in the local paper, I read: "Intelligent, blind widow needs someone to read to her a few hours a week. Special interest in topics of medicine. Excellent compensation." A few hours a week seemed reasonable and wouldn't cut into my study time too seriously. I wondered why was she interested in medicine. Was she a physician? I called and scheduled an interview. Mrs Rodell lived in a huge redbrick house in a nice section of town. A maid answered the door; she led me upstairs to a large bedroom with lace curtains and oriental rugs. Mrs Rodell sat in an immense, four-poster bed and was propped up with several plump
Reduction in motor vehicle collisions following treatment of sleep apnoea with nasal CPAP
Authors: C F P George
Journal: Thorax (2001)

BACKGROUND Patients with untreated obstructive sleep apnoea (OSA) have increased motor vehicle collisions (MVCs). When successfully treated, they report improved driving and fewer mishaps, but there are few objective data to confirm this. A study was therefore undertaken to examine actual MVC data in a large group of patients with OSA before and after treatment with continuous positive airway pressure (CPAP) compared with a control group matched for age, sex, and type of driver's licence (commercial or non-commercial). METHODS Two hundred and ten patients of mean (SD) age 52 (11) years, body mass index (BMI) 35.5 (10) kg/m 2 , apnoea/hypopnoea index (AHI) 54 (29) events/h were treated with CPAP for at least 3 years. MVC records were obtained from the Ontario Ministry of Transportation (MTO) database for patients and an equal number of randomly selected control drivers. MVC rates were compared for 3 years before and after CPAP therapy for patients and for the corresponding time frames for controls. RESULTS Untreated patients with OSA had more MVCs than controls (mean (SD) MVCs/driver/year 0.18 (0.29) v 0.06 (0.17), p&lt;0.001). Following CPAP treatment the number of MVCs/driver/year fell to normal (0.06 (0.17)) while, in controls, the MVC rate was unchanged over time (0.06 (0.17) v 0.07 (0.18), p=NS). Thus, the change in MVCs over time between the groups was very significant (change = –0.12 (95% CI –0.17 to –0.06), p&lt;0.001)). The MVC rate in untreated patients (n=27) remained high over time. Driving exposure was not different following CPAP. CONCLUSIONS The risk of MVCs due to OSA is removed when patients are treated with CPAP. As such, any restrictions on driving because of OSA could be safely removed after treatment.
Prevalence of Overweight and Obesity Among Adults With Diagnosed Diabetes—United States, 1988-1994 and 1999-2002
Journal: JAMA (2005)

Obesity in persons with diabetes is associated with poorer control of blood glucose levels, blood pressure, and cholesterol, placing persons with diabetes at higher risk for both cardiovascular and microvascular disease. Conversely, intentional weight loss is associated with reduced mortality among overweight persons with diabetes. CDC analyzed the prevalence of overweight and obesity among U.S. adults aged >/=20 years with previously diagnosed diabetes by using data from two surveys: the Third National Health and Nutrition Examination Survey (NHANES III), 1988-1994, and NHANES 1999-2002. This report summarizes the results of that analysis, which indicated that most adults with diagnosed diabetes were overweight or obese. During 1999-2002, the prevalence of overweight or obesity was 85.2%, and the prevalence of obesity was 54.8%. Encouraging patients to achieve and maintain a healthy weight should be a priority for all diabetes-care programs.
Exercise therapy in hypertensive men
Authors: J. L. Boyer
Journal: JAMA (1970)

Twenty-three essential hypertensive and 22 normotensive middle-aged men participated in a controlled exercise program for six months; the effect the program had on blood pressures (taken while the men were resting) was determined. There was no other change in therapeutic management during the exercise training period. The exercise medium used was the interval training of the walkjog type, with training intensity based on the actual heart rate expressed as percent of working capacity. A drop in mean diastolic pressure of 11.8 mm Hg and in mean systolic pressure of 13.5 mm Hg occurred in the hypertensive group. There was a mean decrease of 6 mm Hg in the diastolic pressure of the normotensive group, but no significant change in the mean systolic pressure.
Human Hypervariable Sequences in Risk Assessment: Rare Ha-ras Alleles in Cancer Patients
Authors: Theodore G. Krontiris, Nancy A. DiMartino, H. David Mitcheson, Joyce A. Lonergan, Colin Begg, David R. Parkinson
Journal: Environmental Health Perspectives (1987)

A variable tandem repeat (VTR) is responsible for the hyperallelism one kilobase 3' to the human c-Ha-ras-1 (Ha-ras) gene. Thirty-two distinct restriction fragments, comprising 3 allelic classes by frequency of occurrence, have thus far been detected in a sample size of approximately 800 caucasians. Rare Ha-ras alleles, 21 in all, are almost exclusively confined to the genomes of cancer patients (p less than 0.001). From our data we have computed the relative cancer risk associated with possession of a rare Ha-ras allele to be 27. To understand the molecular basis for this phenomenon, we have begun to clone Ha-ras fragments from nontumor DNA of cancer patients. We report here the weak activation, as detected by transfection and transformation of NIH 3T3 mouse cells, of two Ha-ras genes which were obtained from lymphocyte DNA of a melanoma patient. We have mapped the regions that confer this transforming activity to the fragment containing the VTR in one Ha-ras clone and the fragment containing gene coding sequences in the other.
Projections of hypertension-related renal disease in middle-aged residents of the United States
Authors: T. V. Perneger
Journal: JAMA (1993)

<h3>Objective.</h3> —To establish nationwide projections for hypertension-related renal disease among middle-aged residents of the United States and compare disease burden in demographic subgroups. <h3>Design.</h3> —Integrated analysis of data from the US Census, the National Health and Nutrition Examination Survey of 1976 through 1980 (NHANES II), the 1971 through 1975 NHANES I Epidemiologic Follow-up Study, the Hypertension Detection and Follow-up Program trial, and the US Renal Data System. <h3>Population.</h3> —African-American and white residents of the United States, aged 30 to 69 years. <h3>Main Outcome Measures.</h3> —Incidence rates and counts of hypertension, hypertension-related hypercreatinemia, and hypertension-related end-stage renal disease (ESRD). <h3>Results.</h3> —Each year, approximately 1.8 million middle-aged Americans develop hypertension, 140000 develop hypertension-related hypercreatinemia, and 5300 develop hypertension-related ESRD. African Americans are at increased risk for hypertension (relative risk [RR], 1.6; population-attributable risk [PAR], 5%), hypercreatinemia if hypertensive (RR, 2.4; PAR, 18%), ESRD if hypertensive with hypercreatinemia (RR, 2.7; PAR, 32%), and hypertension-related ESRD overall (RR, 8.0; PAR, 44%). Compared with women, men are at increased risk for hypertension (RR, 1.3; PAR, 13%) and hypertension-related ESRD (RR, 1.6; PAR, 23%). Most cases of hypercreatinemia in hypertensives (73%) occur among those with mild hypertension. <h3>Conclusions.</h3> —Progression to ESRD is rare in persons with hypertension-related renal disease, and factors other than blood pressure probably play an important role. A large proportion of hypertension-related renal disease cases occur among population subgroups considered to be at low risk. Interventions that favorably influence factors associated with the progression of hypertension-related renal disease in African Americans, in men, and in persons with mild hypertension, hold the greatest potential for reducing the population burden of hypertension-related ESRD. (<i>JAMA</i>. 1993;269:1272-1277)
Bilharziosis.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Microporous polysaccharide multilayer coated BCP composite scaffolds with immobilised calcitriol promote osteoporotic bone regeneration both <i>in vitro</i> and <i>in vivo</i>: Erratum
Authors: Qian Tang, Zhichao Hu, Haiming Jin, Gang Zheng, XingFang Yu, Gang Wu, Haixiao Liu, Zhenzhong Zhu, Huazi Xu, Changqing Zhang, Liyan Shen
Journal: Theranostics (2021)
Regionalized self-care hemodialysis. A solution to the increasing cost
Authors: J. P. Wauters
Journal: JAMA (1983)

To cope with an ever-increasing number of patients with end-stage renal disease, a regionalized self-care hemodialysis program was set up and combined with the existing home and center hemodialysis, peritoneal dialysis, and renal transplantation. Five years later, of a total of 105 patients treated by hemodialysis, 66 were dialyzing themselves—31 at home and 35 in seven local self-care facilities. This proportion of patients engaging in autonomous treatment (69%) was obtained without restrictive selection criteria, since we treat 210 patients per million population with hemodialysis. The annual intake of new patients could be managed without increasing the number of center dialysis beds and by only slightly increasing the specialized staff. The cost reduction obtained with this program when compared with all center dialysis treatment represents 37%, or approximately 1,200,000 US dollars per year. These results were obtained without compromising the quality of treatment. (<i>JAMA</i>1983;250:59-62)
RAILROAD CO-OPERATION IN PROPHYLAXIS.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Modulatory Effects of Neonatal Exposure to TCDD, or a Mixture of PCBs, p,p prime -DDT, and p-p prime -DDE, on Methylnitrosourea-Induced Mammary Tumor Development in the Rat
Authors: Daniel Desaulniers, Karen Leingartner, Jose Russo, Garth Perkins, Brock G. Chittim, Michael C. Archer, Michael Wade, Jack Yang
Journal: Environmental Health Perspectives (2001)
Regional Enteritis
Authors: Louis Zetzel
Journal: New England Journal of Medicine (1956)

TherapyIn the absence of a specific etiologic agent responsible for the disease, medical management is empirical and symptomatic. Spontaneous resolution is rare except in the early acute, uncomplicated stage found incidentally at operation. In this circumstance, when an acute process is recognized, in the absence of any chronic underlying disease, clinical and even pathological remission is frequent enough to warrant avoidance for the time being of any further definitive surgical treatment, such as sidetracking or resection. In most cases, however, by the time the diagnosis has become definitely established, the pathological changes have progressed beyond this early acute phase . . .
Erratum
Journal: Diabetes Care (2005)

In the section titled "In This Month's Issue of Diabetes Care" for July, the incorrect summary appears for the above-listed article.The correct summary is as follows.An interesting article in which the authors investigated the association of BMI with retinopathy and neuropathy in 592 type 1 diabetic patients.Retinopathy and neuropathy appeared to be more prevalent in overweight type 1 diabetic subjects.However, logistic regression analysis showed that diabetes duration and HbA 1c remain the main determinants for retinopathy and neuropathy.