tbuckley/cabot-search huggingface dataset:
NEW HAMPSHIRE'S VITAL STATISTICS.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Renal Disease
Authors: W. Gordon Walker
Journal: JAMA (1968)

The second edition of this book has been extensively rewritten. Much new material has been added; over half the chapters either represent new topics or have been rewritten by different authors. It remains, in the words of the editor, a "series of substantial essays on important topics" in renal disease rather than a comprehensive treatment of diseases of the kidney. However, in its attempt to present lucid and detailed accounts of important and clinically useful aspects of renal disease, the book is eminently successful. Several contributions merit special comment. The chapter on hydrogen ion and the kidney presents a lucid account of the role of the kidney in the overall hydrogen ion turnover of the body, including the endogenous sources of acid appearing in the urine and the mechanism of the hydrogen ion transport by the kidney. The section on alteration in hydrogen ion transport in various types of renal
Early Scoliosis or Curable Curvatures of the Spine
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TRANSCATHETER AORTIC VALVE REPLACEMENT IN BICUSPID AORTIC VALVE DISEASE
Authors: Darren Mylotte, Thierry Lefevre, Yusuke Watanabe, Lars Sondergaard, Stephan Windecker, Johan Bosmans, Didier Tchetche, Ran Kornowski, Thomas Modine, Jan-Malte Sinning, Crochan O'Sullivan, Marco Barbanti, Pablo Codner, Magdalena Dorfmeister, Joseph Martucci, Peter Wenaweser, Corrado Tamburino, Eberhard Grube, John Webb, Ruediger Lange, Nicolo Piazza
Journal: Journal of the American College of Cardiology (2014)
Error in Author Listing
Journal: JAMA Surgery (2018)

Jennifer Hah, MD, MS; Sean C. Mackey, MD, PhD; Peter Schmidt, MD; Rebecca McCue, BS; Keith Humphreys, PhD; Jodie Trafton, PhD; Bradley Efron, PhD; Debra Clay, BSN, RN; Yasamin Sharifzadeh, BS; Gabriela Ruchelli, BS; Stuart Goodman, MD, PhD; James Huddleston, MD; William J. Maloney, MD; Frederick M. Dirbas, MD; Joseph Shrager, MD; John G. Costouros, MD; Catherine Curtin, MD; Ian Carroll, MD, MS
Is hysterectomy a risk factor for vaginal cancer?
Authors: J. M. Herman
Journal: JAMA (1986)

Several recent case series have called attention to a possible association between previous hysterectomy and the subsequent development of vaginal cancer. To study this relationship, we compared 49 patients with vaginal cancer with 49 controls matched for age, race, and prior cervical dysplasia or neoplasia. Patients and controls were alike in terms of exposure to estrogens. Twenty-four patients (49%) had had prior hysterectomies, of which 13 (27%) were for benign disease. Similarly, 24 controls had a history of a hysterectomy. The matched-pairs odds ratio relating prior hysterectomy to vaginal cancer was 1.00 based on these data, with a 95% confidence interval of 0.47 to 2.12. In the subsample of women without a history of cervical disease, a similar odds ratio appeared. Although the study sample size did not permit exclusion of a twofold increase in risk, the statistical power to detect an actual odds ratio of 2.5 is 76%. At this level of statistical power, our data suggest that hysterectomy has a low probability of being a risk factor for vaginal cancer when age and cervical disease are controlled for. In the absence of such a relationship, screening for vaginal cancer does not appear to be necessary for women who have had a hysterectomy for benign disease. (<i>JAMA</i>1986;256:601-603)
Effects of Toxic Substances on Female Reproduction
Authors: Donald R. Mattison, Maria S. Nightingale, Kenji Shiromizu
Journal: Environmental Health Perspectives (1983)

Successful reproduction requires a complex series of interdependent physiological, cellular and molecular events. In the female many of these interdependent events are vulnerable to interruption by xenobiotic compounds. The physiological steps in the female reproductive cycle are reviewed. Selected xenobiotics which interrupt this cycle are presented and their mechanisms and site of adverse effects are discussed. Finally, a more detailed discussion of chemically induced ovarian failure in the human and an experimental animal model system is presented.
The Pathological Physiology of Surgical Diseases. A Basis for Diagnosis and Treatment of Surgical Affections.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Improving the success of catheter ablation of ventricular tachycardia: A role for ventricular pacing during ablation to stabilize catheter position Gregory T. Altemose, Luis R. Scott, Giselle Gervacio-Domingo, Mark A. Coppess, Douglas P. Zipes, John M. Miller. Indiana University School of Medicine, Krannert Institute of Cardiology, Indianapolis, IN
Journal: Journal of the American College of Cardiology (2001)
Molecular Epidemiology in Environmental Carcinogenesis
Authors: Frederica P. Perera, LaVerne A. Mooney, Christopher P. Dickey, Regina M. Santella, Doug Bell, William Blaner, Deliang Tang, Robin M. Whyatt
Journal: Environmental Health Perspectives (1996)

Molecular epidemiology has significant potential in preventing cancer and other diseases caused by environmental exposures (related to lifestyle, occupation, or ambient pollution).This approach attempts to prevent cancer by incorporating laboratory methods to document the molecular dose and preclinical effects of carcinogens, as well as factors that increase individual susceptibility to carcinogens.Recently we have carried out validation studies of biologic markers such as carcinogen-DNA and carcinogen-protein adducts, gene and chromosomal mutations, alterations in target oncogenes or tumor suppressor genes, polymorphisms in putative susceptibility genes (individual P450s, glutathione transferase Ml), and serum levels of micronutrients.This research involves adults, infants, and children exposed to varying levels of carcinogens, as well as cancer cases and controls.On a group level, dose-response relationships have frequently been seen between various biomarkers and environmental exposures such as polycyclic aromatic hydrocarbons, cigarette smoke (active and passive), and ambient indoor and workplace air pollution.However, there is significant interindividual variation in biomarkers that appears to reflect a modulating effect on biomarkers (hence potential risk) by genetic and acquired susceptibility factors.Ongoing retrospective and nested case-control studies of lung and breast cancer are examining the association between biomarkers and cancer risk.Results of these studies are encouraging; they suggest that biomarkers, once validated, can be useful in identifying populations and individuals at risk in time to intervene effectively.
Treatment of streptococcal pharyngitis revisited
Authors: J. W. Bass
Journal: JAMA (1986)

Penicillin has remained the drug of choice for treatment of patients with streptococcal pharyngitis for the past four decades. From the early 1950s into the 1970s, a single injection of intramuscular penicillin G benzathine, alone or in combination with penicillin G procaine, was the preferred treatment. Because this regimen consistently produced the highest cure rate and because compliance was assured, it evolved as the gold standard with which other treatment regimens were compared. In the late 1960s and the 1970s, studies showed that in private practice settings with counseling as to the need to take oral penicillin for a full ten days to prevent rheumatic fever, good compliance with results equal to intramuscular penicillin G benzathine could be achieved. By the early 1980s, oral treatment was preferred by most primary physicians in the United States. Oral penicillin V in a dosage of 250 mg, twice daily for ten days, affords optimal treatment for children. In areas where rheumatic fever is still prevalent, particularly in poor and crowded inner-city populations where medical care is episodic, follow-up may be lacking, and compliance in taking oral penicillin cannot be relied on, treatment with intramuscular penicillin G benzathine remains preferred. Studies now confirm that early treatment of streptococcal pharyngitis can reduce the duration of symptoms to less than 24 hours in most cases, decrease the incidence of suppurative complications, limit spread of the disease in the family and community, and permit earlier return of the child to school. Recently developed tests that permit rapid, laboratory-confirmed diagnosis of streptococcal pharyngitis directly on the throat swab at the initial clinic visit may soon guide early treatment with these inherent benefits. (<i>JAMA</i>1986;256:740-743)
T-cell chronic lymphocytic leukaemia with pulmonary involvement and relapsing BOOP
Authors: E Vaiman, M Odeh, D Attias, Y Ben-Arie, A Oliven
Journal: European Respiratory Journal (1999)

We report on a case of T-cell chronic lymphocytic leukaemia involving the lung, with clinical, radiological and histological evidence of relapsing bronchiolitis obliterans-organizing pneumonia in a 70-yr-old female. Pulmonary disease was the major clinical manifestation of this chronic lymphocytic leukaemia. The first two episodes of the patient's pulmonary disorder resolved without treatment, and the third episode was treated with cytotoxic agents as part of the leukaemia treatment regimen. Two additional episodes of the pulmonary disorder occurred; both responded to prednisone.
Carcinogenic Activity of Analogues of &lt;italic&gt;p&lt;/italic&gt;-Dimethylaminoazobenzene. VII. Effect of Two Methyl Groups in the Pyridine Series&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt;&lt;xref ref-type="fn" rid="FN3"&gt;3&lt;/xref&gt;
Journal: JNCI Journal of the National Cancer Institute (1968)

This paper completes the series of dimethyl-substituted N,N-dimethyl-4-(4′-[pyridyl-1′-oxide]azo)anilines (J Nat Cancer Inst 37: 365–367, 1966) except for the 3,5-isomer which could not be prepared. The 2′,5′ isomer was the only one of this new group to have strong activity. The remaining isomers have an activity about of the order of p-dimethylaminoazobenzene.
Emerging Neurotechnologies for Lie-Detection: Promises and Perils
Authors: Paul Root Wolpe, Kenneth R. Foster, Daniel D. Langleben
Journal: The American Journal of Bioethics (2005)

Detection of deception and confirmation of truth telling with conventional polygraphy raised a host of technical and ethical issues. Recently, newer methods of recording electromagnetic signals from the brain show promise in permitting the detection of deception or truth telling. Some are even being promoted as more accurate than conventional polygraphy. While the new technologies raise issues of personal privacy, acceptable forensic application, and other social issues, the focus of this paper is the technical limitations of the developing technology. Those limitations include the measurement validity of the new technologies, which remains largely unknown. Another set of questions pertains to the psychological paradigms used to model or constrain the target behavior. Finally, there is little standardization in the field, and the vulnerability of the techniques to countermeasures is unknown. Premature application of these technologies outside of research settings should be resisted, and the social conversation about the appropriate parameters of its civil, forensic, and security use should begin.
Immunotoxicity of PCBs (Aroclors) in Relation to Great Lakes
Authors: Helen Tryphonas
Journal: Environmental Health Perspectives (1995)

Polychlorinated biphenyls (PCBs) are among the most widespread environmental pollutants and a prominent contaminant of the Great Lakes basin.Due to their resistance to biodegradation and lipophilic properties, PCBs bioaccumulate in fish tissues and in fish-eating humans.PCBs are also known to cross the placenta and to be excreted into the mother's milk, thus predisposing the infant to potentially adverse health effects.For example, a higher incidence of bacterial infections was reported for breast-fed infants born to mothers who consumed large amounts of Great Lakes fish compared to the incidence in control infants whose mothers ingested low amounts of fish.While data regarding the PCB-induced immunotoxic effects in humans are scarce, data derived from the use of experimental animals, including nonhuman primates, indicate that the immune system is a potential target for the immunotoxic effects of PCBs.Such studies have used the commercially available PCB mixtures alone.However, PCBs have the potential of partially antagonizing the effects of other structurally related compounds including the highly toxic dioxins, which are also present in small amounts in the Great Lakes.Thus, to fully evaluate the magnitude of the immunotoxic risk PCBs pose to humans, consideration should be given to investigations in which the interactive effects of PCBs are combined with other contaminants present in the Great Lakes.Environ Health Perspect 1 03(Suppl 9):35-46 (1995)
Abstract 2716: What are the Current ICD Implant Patterns Since Expansion of Primary Indications and Support for Cardiac Resynchronization therapy? Data from a Large Multicenter Prospective Registry
Authors: Dan Goldman, Andrew Epstein, Thomas Deering, Steven Greenberg, Jeff Shafiroff
Journal: Circulation (2007)

With the publication of MADIT II in 2002 and SCD-HeFT in 2004, primary device implant indications have expanded; and with the COMPANION trial in 2005 supporting the benefit of biventricular devices, the number of ICD implants has increased further. Since these trials, data on implant patterns in a large group of patients from multiple centers has not been reported. The Advancements in ICD Therapy (ACT) prospective implant registry is a non-consecutive patient study developed to track such a group undergoing device implantation. Data on device and lead performance, arrhythmic events and mortality are tracked. Methods: Over a 19 month period from November 2004.to June, 2006, 5454 devices were implanted at 286 centers in 38 states in the United States. Patients where enrolled within 2 weeks of implant. Patients are being followed for a period of 2 years at 6 month intervals with device interrogations performed at each visit. Primary prevention patients are those who met MADIT II, SCD-HeFT or DEFINITE criteria as well as those with inheritable conditions. Results: Of the 5,454 patients, 402 had generator replacements and are excluded from this report. There where 464 device upgrades. Of the 4578 evaluable patients undergoing first implantation, 3,629 (79.3%) were for a primary prevention indication, and 20.7% for a secondary prevention indication. Biventricular devices were implanted in 1,905 patients (37.7% of total) with 135 of these being device upgrades. Male patients constitute 75.3% (n = 3,806) of the implant group and the median age at enrollment was 67 years. Median patient ejection fraction was 16%, (Interquartile Range 11% to 21%), with 88.6% having ejection fractions ≤ 35%, reflecting a fairly ill cohort. Conclusions: In a current large, multicenter ICD implant registry, the overwhelming majority of patients underwent ICD implantation for a primary prevention indication. Cardiac resynchronization therapy devices were implanted in approximately one third of the patients Even with expanded indications for implantation, this is a patient cohort with apparent advanced disease states evidenced by their low ejection fractions.
Effects of obesity and smoking on survival in non-small cell lung cancer.
Authors: Damien Mikael Hansra, Tulay Koru-Sengul, Wei Zhao, Feng Miao, Stacey L. Tannenbaum, Alicia P Monedero, David J. Lee, Jorge Antunez de Mayolo, Judith Hurley, Margaret M Byrne
Journal: Journal of Clinical Oncology (2015)

7534 Background: Obesity is an emerging leading cause of morbidity and mortality in the US & the relationship between obesity, tobacco, & survival in NSCLC is unclear. Methods: Data (n = 87,631) were obtained from linkage of the 1996-2007 FCDS & AHCA databases providing procedure and diagnoses codes. Survival time was calculated from date of diagnosis to date of death. Smoking status was categorized as never, current, and former. Obesity (yes/no) = ICD9 code BMI > 30kg/m2, cachexia = ICD9 code “wasting syndrome”, & non-obese = non-obese & non cachectic. Cox proportional regression models used to predict survival; demographic, clinical, treatment factors, & comorbidities were included in adjusted models with smoking status and obesity as the main factors. Results: The majority of patients (pts) were either former (49%) or current (40%) smokers, & non-obese (88%). 6.8% of pts were obese & 4.8% of pts were cachectic. There were significant differences between survival curves & median survival (months) for obese vs. non-obese vs. cachectic pts. (20 vs. 10 vs. 7.9; P < .001). Former & current smokers had shorter median survival than never smokers (10.8 & 9.2 vs. 11.9; P < .001). Survival rates (%) at 1-yr (60.1 vs. 45.2 vs. 37.7; P < .001), 5-yr (30.3 vs. 15.4 vs. 9.5; P < .001), 10-yr (18.1 vs. 7.6 vs. 2.7; P < .001) were better for obese vs. non-obese & cachectic pts respectively. Independent predictor of worse survival in unadjusted model was former (HR 1.08; P < .001) & current (HR 1.20; P < .001) smokers compared to never. Obese & non-obese pts had better survival vs. cachexia pts(HR 0.52; P < .001 and HR 0.80, p < .001 respectively) & obese pts had better survival than non-obese pts (HR 0.65, p < .001). In the adjusted model, controlling for extensive variables & comorbidities, former (HR 1.11; P < .001) & current (HR 1.19; P < .001) smokers still had significantly worse survival vs. never smokers. Obese pts still had better survival (HR 0.87; P < .001, & HR 0.88, p < .001) vs. cachexia & non-obese pts respectively, survival rate is not significantly different comparing non-obese & cachexia pts. Conclusions: Our results show that being a former or current smoker worsens survival while obesity improved survival when compared with cachexia & non-obese pts.
Physiology of pentathlon performance
Authors: J. Daniels
Journal: JAMA (1972)

The modern pentathlon is an Olympic event which consists of horseback riding over obstacles, épée fencing, pistol shooting, swimming, and running. As a whole, the pentathlon is a skill-oriented event that demands a high degree of general fitness and utilization of aerobic and anaerobic mechanisms. Training in the various sports must be organized in a manner such that conditioning of a physiological system common to more than one sport is not overemphasized and that training for one sport does not adversely affect adequate preparation or participation in another. Generally, this requires emphasis on technique training prior to more strenuous conditioning of energy-supplying systems. An actual pentathlon competition takes place during a five-day period and does not present the problems normally encountered in practice.
Relapse
Authors: Floyd Skloot
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal