tbuckley/cabot-search huggingface dataset:
FEMORAL HERNIA OF THE OVARY
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Essentials of Hospital Practice: A Guide for Students and Interns
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Child Passenger Restraint Use and Motor Vehicle-Related Fatalities Among Children— United States, 1982-1990
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE MODERN SUBJECTION OF SCIENCE AND EDUCATION TO PROPAGANDA.*
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sanitas sanitatum
Authors: Jeremy Hugh Baron
Journal: BMJ (2005)

8-Methyl-<i>N</i>-vanillyl-6-nonenamide (capsaicin) was locally applied in the tail of rhesus monkeys to evoke a nociceptive response, thermal allodynia, which was manifested as reduced tail-withdrawal latencies in normally innocuous 46°C water. Coadministration of three<i>κ</i> opioid ligands, U50,488 (3.2–100 μg), bremazocine (0.1–3.2 μg), and dynorphin A(1–13) (3.2–100 μg), with capsaicin in the tail dose-dependently inhibited capsaicin-induced allodynia. This local antinociception was antagonized by a small dose of an opioid antagonist, quadazocine; (0.32 mg), applied in the tail; however, this dose of quadazocine injected s.c. in the back did not antagonize local U50,488. Comparing the relative potency of either agonist or antagonist after local and systemic administration confirmed that the site of action of locally applied <i>κ</i> opioid agonists is in the tail. In addition, local nor-binaltorphimine (0.32 mg) and oxilorphan (0.1–10 μg) antagonist studies raised the possibility of <i>κ</i> opioid receptor subtypes in the periphery, which indicated that U50,488 produced local antinociception by acting on <i>κ</i><sub>1</sub> receptors, but bremazocine acted probably on non-κ<sub>1</sub> receptors. These results provide functional evidence that activation of peripheral κ opioid receptors can diminish capsaicin-induced allodynia in primates. This experimental pain model is a useful tool for evaluating peripherally antinociceptive actions of <i>κ</i> agonists without central side effects and suggests new approaches for opioid pain management.
The acute cardiac risk of strenuous exercise
Authors: L. W. Gibbons
Journal: JAMA (1980)

During a 65-month period, 2,935 adults (mean age, 37 years) kept computer logs of amount and intensity of exercise performed. A total of 374,798 person-hours of exercise, including 2,726,272 km of running and walking, was recorded. Two cardiac events and no deaths occurred during this period. Considered in age-specific categories, the maximum risk estimates (MREs) consistent with these data (upper 95% confidence limits) range from 0.3 to 2.7 events per 10,000 person-hours of exercise for men and 0.6 to 6.0 events per 10,000 person-hours for women. The MREs for women were higher because there were fewer women in the study. If exercise were performed three times per week for 30 minutes per session for a year, these results would lead to MREs from.002 to.027 events per person-year for men and.005 to.05 events per person-year for women. Actual risks are likely to be lower. (<i>JAMA</i>244:1799-1801, 1980)
Patriotic gore. Introduction to Civil War books by physicians
Authors: P. E. Steiner
Journal: JAMA (1967)

In 1861 the physicians of this country, North and South, contributed their patriotic ardor to the general pools. Eventually about 15,400 served as medical officers—12,000 Federal and 3,400 Confederate. Without any indoctrination in military medicine, and in some states without any examination for proficiency, they bought their uniforms, horses, and accoutrements, packed their surgical cases and medicine bags, and rode off to join their regiments in camp, field, or battle. Additional thousands enlisted as combatants. Some became medical officers; many, however, remained in the ranks or were promoted to be company or regimental officers, and at least 33 finally became combatant generals.<sup>1</sup>The two groups, the medical and nonmedical, contained a high proportion of the country's physicians. The regimental doctors were designated surgeons and assistant surgeons. One of each was assigned to a regiment, originally containing about a thousand men. The regiments were the basic, important units. They were recruited
DANGER OF INFECTION FROM CIGAR-CLIPPERS.OCULAR DEFECTS AND HEADACHE.
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Propanolol does not decrease the development of large esophageal varices in patients with cirrhosis. A controlled study Groupe Fran�ais de la Pr�vention Pr�-Primaire*
Journal: Hepatology (1995)

Background & Aims: During acute variceal bleeding, several factors may lead to elevations of hepatic venous pressure gradient (HVPG), which may precipitate further hemorrhage. Whether somatostatin can suppress these increments is unknown. This study monitored somatostatin effects on HVPG during acute bleeding and assessed whether the changes affect outcome. Methods: In 40 patients with acute variceal bleeding treated with sclerotherapy, a catheter was placed into a main hepatic vein for 24-hour serial measurements of HVPG. After baseline measurements, patients received somatostatin (N = 25) or placebo (N = 15) under double blind conditions. Results: Somatostatin but not placebo produced a sustained decrease in HVPG (from 20.7 ± 3.7 mm Hg to 17.7 ± 2.7, P < 0.01). In patients receiving placebo, HVPG increased after a test meal (P = 0.018) and after blood transfusion (P = 0.034). Somatostatin completely prevented these increments. HVPG decreased significantly only in patients without further bleeding. One of 27 patients with HVPG <20 mm Hg at baseline or decreased >10% rebled vs. 9 of 13 who had neither of these 2 criteria (P < 0.0001). Both criteria had independent prognostic value for further bleeding. Conclusions: During acute variceal bleeding, somatostatin produces a significant and sustained decrease in HVPG and prevents secondary elevations. Monitoring HVPG may stratify further bleeding risk and discriminate treatment response.
SURGICAL TREATMENT OF GENERAL PARALYSIS
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Drugs for diarrhoea.
Journal: BMJ (1969)

Virus C.N.S. Disease-Webb MEDICALTIJSNAL I.U.D.R. has some hepatotoxic effects and produces a leucopenia, and at the moment there is no convincing scientific evidence that it is beneficial in encephalitis.It is certainly an antiviral agent and from it may be developed something that is useful.There are other drugs, too, at the experimental stage in animals, such as daunomycin, which inhibits DNA synthesis and synthesis of DNA-dependent RNA.Actinomycin D, an antibiotic derived from Streptomyces antibioticus, also inhibits DNA viruses because it has an affinity for guanine.Because of this it attaches itself to the DNA, and, possibly by altering the molecular configuration of the nucleic acid, it blocks the action of DNA-dependent RNA polymerase.There is also rifampicin, which is believed to act directly on the DNA- dependent RNA polymerase enzyme.So there is some hope that there, may be an effective and safe antiviral agent in the not too distant future. Chronic EncephalomyelitidesLastly, one must consider the management of the chronic encephalomyelitides.So little is understood of the aetiological factors in these conditions that apart from symptomatic therapy the rest is guesswork.If there is a proliferative phenomenon at work, as denoted by the intense gliosis seen in many of these diseases, then it would be reasonable to try drugs such as vincristine, 6-mercaptopurine, and methotrexate, as in malig- nant disease generally.This would also apply if immuno- logical mechanisms were concerned in the slowly progressive disease.In both acute and chronic encephalomyelitis changes of personality, depression, and other psychiatric disturbances occur.They should be treated on their own merits.E.C.T. and antidepressive drugs are frequently helpful in treating depressions after a viral C.N.S. disturbance.These forms of therapy are not contraindicated even though one feels the psychiatric disturbance has been induced by organic brain damage.Treatment is frequently very helpful.I am very grateful to Dr. G.
Case-control study of risk of cerebral sinus thrombosis in oral contraceptive users who are carriers of hereditary prothrombotic conditions
Journal: BMJ (1998)

Objectives: To evaluate impact of postnatal health education for mothers on infant care and postnatal family planning practices in Nepal.Design: Randomised controlled trial with community follow up at 3 and 6 months post partum by interview.Initial household survey of study areas to identify all pregnant women to facilitate follow up.Setting: Main maternity hospital in Kathmandu, Nepal.Follow up in urban Kathmandu and a periurban area southwest of the city.Subjects: 540 mothers randomly allocated to one of four groups: health education immediately after birth and three months later (group A), at birth only (group B), at three months only (group C), or none (group D).Interventions: Structured baseline household questionnaire; 20 minute, one to one health education at birth and three months later.Main outcome measures: Duration of exclusive breast feeding, appropriate immunisation of infant, knowledge of oral rehydration solution and need to continue breast feeding in diarrhoea, knowledge of infant signs suggesting pneumonia, uptake of postnatal family planning.Results: Mothers in groups A and B (received health education at birth) were slightly more likely to use contraception at six months after birth compared with mothers in groups C and D (no health education at birth) (odds ratio 1.62, 95% confidence interval 1.06 to 2.5).There were no other significant differences between groups with regards to infant feeding, infant care, or immunisation.Conclusions: Our findings suggest that the recommended practice of individual health education for postnatal mothers in poor communities has no impact on infant feeding, care, or immunisation, although uptake of family planning may be slightly enhanced.
HUMANE OR INHUMANE PROJECTILES IN WAR.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chemical-biological warfare in Asia
Authors: R. C. Harruff
Journal: JAMA (1983)

DURING the first six months of 1980, I was involved in the Indo-Chinese refugee relief effort in Thailand as a volunteer physician at Ban Vinai camp. This camp is the principal refuge of the Laotian Hmong population, who are enemies of the Communist Pathet Lao and Vietnamese governments because of the Hmong's collaboration with the United States in the war with North Vietnam. After the war, the Hmong maintained a strong resistance to Vietnam's troops until 1979, when they were defeated at Phu Bia, Laos. Now most of the Hmong are either refugees or under control of the Vietnamese occupying force, although the resistance continues on a much reduced level. Since 1976, there have been accounts by the Hmong of chemical-biological warfare activity against their fighters and their villages and in experimentation programs. Although this was not an issue at the time I was in Ban Vinai, I had evaluated
Hospital Discharges Against Medical Advice: I. Origin and Prevention
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Year of Magical Thinking
Authors: John Quin
Journal: BMJ (2005)

R elatives. Rellies. One of the relatives wants to speak to you. Heartsink. Fair enough, we say—bring them on—but what if the daughter in bed six with the subdural had an international normalised ratio greater than four before she came in? What if said rellie has bought various textbooks on neurosurgery and checks out the New England Journal of Medicine online? What if mum is one of America's most astute and gimlet eyed commentators of modern times? What if mother is none other than the acclaimed US writer and novelist Joan Didion? Joan Didion Fourth Estate, £12.99, pp 240 ISBN 0 00 721684 X Rating:![Graphic][1]</img>![Graphic][2]</img>![Graphic][3]</img>![Graphic][4]</img> “If you want to manage this case I'm signing off.” So concludes one stressed out intensive therapy unit (ITU) medic at UCLA (the University of California, Los Angeles), and Didion brilliantly delineates here why she has provoked such a response, why relatives can often become irrational, how her reasoning “was demented, but so was I.” Didion's husband, the writer John Gregory Dunne, … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif [3]: /embed/inline-graphic-3.gif [4]: /embed/inline-graphic-4.gif
Bladder Cancer
Authors: James E. Montie, Peter E. Clark, Mario A. Eisenberger, Rizk El-Galley, Richard E. Greenberg, Harry W. Herr, Gary R. Hudes, Deborah A. Kuban, Timothy M. Kuzel, Paul H. Lange, Subodh M. Lele, Jeffrey Michalski, Anthony Patterson, Kamal S. Pohar, Jerome P. Richie, Wade J. Sexton, William U. Shipley, Eric J. Small, Donald L. Trump, Phillip J. Walther, Timothy G. Wilson
Journal: Journal of the National Comprehensive Cancer Network (2009)

Clinical Practice Guidelines, bladder
Preclinical deposition of pathological prion protein PrPSc in muscles of hamsters orally exposed to scrapie
Authors: Achim Thomzig, Walter Schulz-Schaeffer, Christine Kratzel, Jessica Mai, Michael Beekes
Journal: Journal of Clinical Investigation (2004)

Recently, pathological prion protein PrPSc, the putative key constituent of infectious agents causing transmissible spongiform encephalopathies (TSEs), was found in muscles of rodents experimentally infected with scrapie and in patients with Creutzfeldt-Jakob disease (CJD). For the assessment of risk scenarios originating from these findings (e.g., alimentary transmission of pathogens associated with bovine spongiform encephalopathy [BSE] and chronic wasting disease [CWD] via tainted beef and game or iatrogenic dissemination of CJD agent through contaminated surgical instruments) more detailed information about the time course of PrPSc accumulation in muscles at preclinical and clinical stages of incubation is needed. Here we show that PrPSc in muscles of hamsters fed with scrapie can be detected prior to the onset of clinical symptoms, but that the bulk of PrPSc was deposited late in clinical disease. Additionally, regarding the question of how muscles become invaded, we report on the intramuscular location of PrPSc and substantial indications for centrifugal spread of infection from spinal motor neurons to myofibers. Our findings in a well-established animal model for TSEs contribute to a better assessment of the risks for public health emanating from "Prions in skeletal muscle" and provide new insights into the pathophysiological spread of TSE agents through the body.