tbuckley/cabot-search huggingface dataset:
Hepatic changes in young women ingesting contraceptive steroids. Hepatic hemorrhage and primary hepatic tumors
Authors: E. T. Mays
Journal: JAMA (1976)

Primary hepatic tumors developed in 13 young women who had been ingesting contraceptive steroids. Nine tumors were benign, and four malignant. Six tumors ruptured spontaneously and caused life-threatening hemorrhage. Benign tumors were successfully resected in eight women. One woman died during hepatic resection for malignant hepatoma; in two other cases of hepatocellular carcinoma, tumors were nonresectable. In two patients, the tumor was left in situ after neoplasm had been excluded by biopsy. The increase of such tumors in women of childbearing age warrants the suspicion that these contraceptive steroid hormones play an etiologic role. (<i>JAMA</i>235:730-732, 1976)
Unilateral Ureteral Obstruction
Authors: Norman J. Nemoy
Journal: JAMA (1973)

A patient with unilateral ureteral obstruction at the ureteropelvic junction had hypertension of one year's duration. Increased activity of the renin-angiotensin system was documented by means of renal vein renin concentrations. Following relief of the obstruction, the patient became normotensive and has remained so for the last two years.
Anxiety and pain
Authors: A. S. Rose
Journal: JAMA (1969)

<h3>To the Editor:—</h3> I have always been impressed with the ingenuity displayed in the selection of cover art in color. The Aug 11 cartoon by Cruikshank tops them all. That doctors disagree, at times violently, should come as a surprise only to those who are ignorant of the history of medicine. It was a particularly fitting choice for the topic of sex education. The original of the Cruikshank cartoon is in the Huntington Library and Art Gallery in San Marino, Calif, where I live, and where there has been, over the last eight months, a great controversy over a proposed Family Life and Sex Education course. Having been a member of the committee, and having devoted a good many hours of prime time, I found it a fascinating and frustrating experience.
A randomized clinical trial of active compression-decompression CPR vs standard CPR in out-of-hospital cardiac arrest in two cities
Authors: T. M. Schwab
Journal: JAMA (1995)

<h3>Objective.</h3> —To compare the effectiveness of active compression-decompression (ACD) cardiopulmonary resuscitation (CPR) with a handheld suction device vs standard manual CPR in victims of out-of-hospital cardiopulmonary arrest. <h3>Design.</h3> —Prospective randomized clinical trial with crossover group design. <h3>Setting.</h3> —Emergency medical services (EMS) of a large (San Francisco) and medium-sized (Fresno) city in California. <h3>Patients.</h3> —All normothermic adult victims of out-of-hospital, nontraumatic cardiac arrest on whom CPR was performed by first responders. <h3>Intervention.</h3> —Patients were randomized to receive either standard manual CPR according to American Heart Association guidelines or ACD CPR, on first-responder contact. <h3>Main Outcome Measures.</h3> —Return of spontaneous circulation, admission to the intensive care unit, survival to hospital discharge, and neurological function at hospital discharge. <h3>Results.</h3> —The ACD group (n=117 in Fresno; n=297 in San Francisco) and standard group (n=136 in Fresno; n=310 in San Francisco) were similar with regard to demographic and prognostic variables, such as age, witnessed arrest and bystander CPR frequency, and initial cardiac rhythm. Average interval from 911 call activation to EMS responder arrival was 6.4 minutes in Fresno and 4.0 minutes in San Francisco. In Fresno, there was no difference between the ACD group and standard CPR group in return of spontaneous circulation (17% vs 20%;<i>P</i>=.68), hospital admission (16% vs 20%;<i>P</i>=.56), hospital discharge (5% vs 7%;<i>P</i>=.64), or cerebral performance category score at discharge (1.5 vs 1.6;<i>P</i>=.90). Similarly, in San Francisco there was no difference between the ACD group and standard CPR group in return of spontaneous circulation (19% vs 21%;<i>P</i>=.65), hospital admission (13.5% vs 14.5%;<i>P</i>=.79), hospital discharge (4.7% vs 5.5%;<i>P</i>=.80), or cerebral performance category score at discharge (2.2 vs 2.6;<i>P</i>=.31). There was no increase in significant complications associated with the use of ACD CPR. <h3>Conclusion.</h3> —There was no improvement in outcome with ACD CPR in out-of-hospital cardiac arrest in these two cities. Differences in study design, demographics, EMS systems, response intervals, training, and technique performance may contribute to the lack of improvement in initial resuscitation with ACD CPR compared with previous studies. Future research needs to control these variables to determine the reason for these differences in outcome. (<i>JAMA</i>. 1995;273:1261-1268)
Acute Focal Edema of the Brain in Children with Head Injuries
Authors: Wilfred Pickles
Journal: New England Journal of Medicine (1949)

ON MARCH 18, 1943, the very active two-and-a-half-year-old son of a surgical colleague fell from his high chair with such force that his head bounced on the floor. He seemed dazed for a moment or two but had no definite period of unconsciousness. He cried loudly for a few minutes, as one might expect, but soon seemed to forget all about the fall and was apparently as well as ever. He ate his supper with a good appetite, and was put to bed. Two hours later he began to vomit; he was very pale and his skin was moist and . . .
AMEBIC DYSENTERY
Authors: Henry E. Meleney
Journal: JAMA (1933)

<h3>To the Editor:</h3> —I wish to congratulate you on the excellence of the articles and the editorial on amebic dysentery that appeared inThe Journal, November 18. Although it is regrettable that an epidemic of amebic dysentery should have started in connection with the Century of Progress Exposition, perhaps no better method of emphasizing the importance of this condition in the country as a whole could have been found. The wide publicity given to this epidemic will undoubtedly lead to the discovery of many cases of amebiasis throughout the country and a better understanding of the disease. I think it is particularly important to emphasize, as a supplementary point in the diagnosis of amebiasis, that, in addition to Endamoeba histolytica, man is known to harbor in his intestine at least four other amebas, none of which are pathogenic. It is just as important to be able to differentiate these amebas
Guidelines for Treating Dementia-Associated Agitation
Authors: M. F. Goldsmith
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Trauma systems. Current status--future challenges
Authors: J G West, M J Williams, D D Trunkey, C C Wolferth
Journal: JAMA (1988)

The national status of regional trauma system development was evaluated by a survey sent to all state emergency medical services directors and state chairpersons of the American College of Surgeons Committee on Trauma. Eight essential components of a regional trauma system based on criteria set forth by the American College of Surgeons were listed. Only two states were found to have all components and statewide coverage. Nineteen states and the District of Columbia lacked one or more components of a regional trauma system. The remaining 29 states had yet to initiate the process of trauma center designation. In response to these shortcomings, an attempt was made to define the barriers to trauma system implementation and a step-by-step process was outlined for the development, management, and analysis of a comprehensive system of trauma care. (<i>JAMA</i>1988;259:3597-3600)
Court of Queen's Bench: Tuesday, May 25, 1841. the Society of Apothecaries v. Greenough
Journal: BMJ (1841)

APOTHECAItIES' SOCITY v. GREINOMtGII 211 tient quiet in bed, and by the adoption of various anliphiogistic measures, the effused blood was absorbed, acute inflammation was prevented, and the patient's vision so far restored that he has this day read to me, with tolerable ease, and without glasses, a portion of the former part of his case published in the sixth part of the Transactions.'l'he pupil I have made has a smooth margin, being formed, not by excising a portion of iris, but by detaching its pupillary margin froiii the staphylomatous cornea, to which it was extensively adherent; it is of good size, being neither very large nor unusually small; it is somewvhat oval in shape, and extends from the upper border of the staphyloma nearly to the corneal margin at its su- perior part where I made the incision.-Transac.
Gastroplastie endoscopique ou ballon intragastrique: efficacité, durabilité et sécurité
Journal: Endoscopy (2019)

L’obésité est devenue une pathologie épidémique et la prise en charge nutritionnelle seule est peu efficace. La chirurgie a démontré son efficacité mais elle est réservée aux malades atteints d’obésité sévère car elle est associée à une morbi-mortalité.
Erratum: Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents
Authors: Nicole E Burma, Robert P Bonin, Heather Leduc-Pessah, Corey Baimel, Zoe F Cairncross, Michael Mousseau, Jhenkruthi Vijaya Shankara, Patrick L Stemkowski, Dinara Baimoukhametova, Jaideep S Bains, Michael C Antle, Gerald W Zamponi, Catherine M Cahill, Stephanie L Borgland, Yves DeKoninck, Tuan Trang
Journal: Nature Medicine (2017)
Human CIA2A-FAM96A and CIA2B-FAM96B Integrate Iron Homeostasis and Maturation of Different Subsets of Cytosolic-Nuclear Iron-Sulfur Proteins
Authors: Oliver Stehling, Judita Mascarenhas, Ajay A. Vashisht, Alex D. Sheftel, Brigitte Niggemeyer, Ralf Rösser, Antonio J. Pierik, James A. Wohlschlegel, Roland Lill
Journal: Cell Metabolism (2018)
Junior Hospital Staff Contract
Authors: A. J. Ahmad, P. J. Barnes, V. Bentham, L. J. Blumhardt, P. G. Cleland, A. Danziger, P. Dowd, S. R. Dunn, R. F. Cledhill, H. Harrington, C. H. Howard, W. Hung, J. Jestico, S. Kahn, P. Kennedy, N. Lawton, L. M. Luxon, J. MacDermot, P. N. Maton, J. G. L. Morris, S. N. Ofole, N. Palmer, R. C. Peatfield, J. D. Pollard, J. R. Ponsford, J. W. Scadding, G. D. Schott, R. M. Sherratt, E. J. Thompson, C. P. Warlow, L. A. Wilson, P. C. W. Taylor, R. L. Zimmern
Journal: BMJ (1975)
Essais et dosages biologiques des substances médicamenteuses.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Thanksgiving
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Grapes
Authors: M. Therese Southgate
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE ATAXIC VARIETY OF ALCOHOLIC MULTIPLE NEURITIS—SO-CALLED PERIPHERAL NEUROTABES.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Germinal Centers
Authors: Gabriel D. Victora, Michel C. Nussenzweig
Journal: Annual Review of Immunology (2012)

Germinal centers (GCs) were described more than 125 years ago as compartments within secondary lymphoid organs that contained mitotic cells. Since then, it has become clear that this structure is the site of B cell clonal expansion, somatic hypermutation, and affinity-based selection, the combination of which results in the production of high-affinity antibodies. Decades of anatomical and functional studies have led to an overall model of how the GC reaction and affinity-based selection operate. More recently, the introduction of intravital imaging into the GC field has opened the door to direct investigation of certain key dynamic features of this microanatomic structure, sparking renewed interest in the relationship between cell movement and affinity maturation. We review these and other recent advances in our understanding of GCs, focusing on cellular dynamics and on the mechanism of selection of high-affinity B cells.
NAFLD is a rising cause of HCC in women in a prospective populational cohort spanning 24 years (1990–2014)
Authors: Shuna Myers, Konstantinos Gkouvatsos, Laurent Spahr, Emiliano Giostra, Francesco Negro, Jean-Louis Frossard, Evelyne Fournier, Marie-Eve Bascaron, Isabelle Neyroud, Nicolas Goossens
Journal: Journal of Hepatology (2020)
Catching cold may not be as easy as it seems
Authors: C. A. Raymond
Journal: JAMA (1986)

Colds are transmitted primarily through hand-to-hand contact, not through airborne particles, at least when rhinoviruses and respiratory syncytial viruses are involved, according to investigators at the University of Virginia (<i>Ann Intern Med</i>1978;88:463-467;<i>J Pediatr</i>1981;99:100-103;<i>Am J Epidemiol</i>1982;116:828-833). Respiratory viruses theoretically can be transmitted in three ways: small particle aerosols (primarily from coughing), large particle aerosols (coughing and sneezing), and direct or indirect contact with objects contaminated with virus. Transmission starts with viral shedding, most commonly from nasal secretions. Cold viruses are ten to 100 times more prevalent in the nasal than in the pharyngeal mucosa. Knowing this, J. Owen Hendley, MD, and Jack M. Gwaltney, Jr, MD, both of the University of Virginia, Charlottesville, began to doubt that airborne particles expelled from nasal secretions could be the primary means of transmission. They set up a series of experiments, alternately testing the three likely transmission routes (<i>J Respir</i>
Transplantation immunology
Authors: C. H. Kirkpatrick
Journal: JAMA (1987)

TRANSPLANTATION of tissues and organs is an artificial biologic event, but it has provided a means for temporary or long-term treatment for failure of a variety of organs. Corneal transplantation has restored sight to thousands of persons,<sup>1</sup>and skin grafts are regularly used to cover injured tissues in burn patients. Since the 1960s, kidney transplantation has prolonged the healthy and productive lives of many persons with chronic renal failure.<sup>2</sup>Transplantation of bone marrow is widely used for treatment of aplastic anemia<sup>3-5</sup>and is beneficial for some patients with malignant diseases such as leukemia<sup>6-9</sup>or immune deficiency syndromes.<sup>10</sup>Bone marrow transplantation is also being evaluated as a method for correction of certain genetically determined diseases.<sup>11</sup>During recent years, transplantation of the heart<sup>12-14</sup>and liver<sup>15,16</sup>has become common, and progress is being made toward successful transplantation of the lung,<sup>17</sup>pancreas,<sup>18</sup>and other organs.
Open-Heart Surgery and Hemorrhagic Necrosis
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Naturalness of Dying
Authors: Jack D. McCue
Journal: JAMA (1995)

Evidence that dying occurs as a natural, final event in the wholeness of human life is culturally, artistically, and scientifically persuasive. Very elderly patients eventually undergo a process of functional declines, progressive apathy, and loss of willingness to eat and drink that culminates in death, even in the absence of acute illness or severe chronic disease. Despite clinical resemblances to depression and dementia, aging itself and a loss of will to live are the most probable explanations for natural dying. Acceptance of the naturalness of dying, however, directly conflicts with the medicalization and legalization of death that characterizes modern society's treatment of dying elderly patients. We prefer instead to believe that dying results from disease and injury, which may yield to advances in medical technology. The progressive move of the dying out of the home and into acute and long-term care facilities suggests that medicalization may be an irreversible process. Viewing dying as an independent diagnosis in patients who are obviously undergoing terminal declines from aging and chronic diseases can facilitate communication about spiritual and palliative care needs, which tend to be neglected in the medicalized view of dying. Physicians and nurses may need to assume the role of medical stewardship to help prevent the overtreatment and overtesting of modern medicine's approach to the dying. The emotional burdens of caring for the dying elderly, however, must be addressed openly through collaborative work, institutional policies on limitation of treatment, and support building among physicians and other caregivers. (<i>JAMA</i>. 1995;273:1039-1043)
Impact of beta blocker therapy on systemic inflammation stratified by hepatic venous pressure gradient response
Authors: Mathias Jachs, Lukas Hartl, Dunja Schaufler, Christopher Desbalmes, Ernst Eigenbauer, Thomas Szekeres, Rodrig Marculescu, Rafael Paternostro, Benedikt Simbrunner, Philipp Schwabl, Theresa Bucsics, David JM Bauer, Michael Trauner, Mattias Mandorfer, Thomas Reiberger
Journal: Journal of Hepatology (2020)