tbuckley/cabot-search huggingface dataset:
The carrot or the stick
Authors: W. C. Bornemeier
Journal: JAMA (1973)

For many years past, the number of specialists trained in any particular field has been determined by accident or by the appeal of the specialty. To a certain extent, it has been the carrot at the end of the stick that has induced medical students to select a certain future field of endeavor. Sometimes the carrot has taken the form of a dollar sign, sometimes leisure time, sometimes prestige in diagnosis or treatment. Never has the selection been due to adequate guidance or by an attempt by organized medicine to provide an equitable balance in the product of our educational process. The needs of the sick people of this country have been completely ignored. Who should be responsible for creating a proper balance of specialists to care for the needs of our people? The federal government has told the farmer how many acres of corn or wheat or beans that
Modern Gynecology. A Treatise on Diseases of Women, comprising the results of the latest investigations and treatment in this branch of medical science.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
New England Journal of Medicine, Boston
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Metabolic control and complications in diabetic patients
Authors: R. M. Bergenstal
Journal: JAMA (1981)

In this issue we introduce a new section ofThe Journalthat will present the points of view of distinguished clinicians and researchers on topics of general medical interest. Since the articles in this section will express the personal perspectives of these clinicians, we call it CLINICAL PERSPECTIVES (p 689). In the interviews that will constitute CLINICAL PERSPECTIVES, we have invited comments and speculations concerning the future directions of medicine. Experts will present unpublished data and describe new technologies. It is an unfortunate feature of the current medical literature that many research advances are either buried or fragmented in ways that make them difficult to locate, let alone to synthesize into a unified picture. It is also difficult for practitioners who are unacquainted with the arcane details of specialized medical research areas to assess the relative importance of published findings. Yet, such assessments are important to keep one's practice current.
Self-Incompatibility Systems as Bioassays for Mutagens
Authors: David L. Mulcahy, Claire M. Johnson
Journal: Environmental Health Perspectives (1978)

Many flowering plants are unable to set seeds with their own pollen because a system known as gametophytic self-incompatibility is operating. The basis of this system is a single multiallelic locus S, and if the S allele carried by a pollen grain matches one of the two S alleles carried in the style, as it is certain to do upon self-pollination, then pollen tube growth is inhibited. Should one of the self-pollen grains carry a mutated S allele, however, it would not match either of those carried in the style and would therefore, not be inhibited. Gametophytic self-incompatibility thus provides a mechanism for discriminating between such mutant and nonmutant pollen grains. Knowing the numbers of pollen grains available to the stigma, and also the numbers of seeds produced, it becomes possible to estimate the frequency with which mutations occur at the S locus. Assay systems of mutagenesis which employ gametophytic self incompatibility will allow very large numbers of pollen grains to be screened for S allele mutants, which should indicate the mutagenicity of the environment. These systems have the added benefit that screening is done by the stylar tissues, rather than technicians. Finally, they may be used to construct largely autonomous assay systems which would provide continuous monitoring of the environment.
Chymopapain Chemonucleolysis In Lumbar Disk Disease-Reply
Authors: L. L. Wiltse
Journal: JAMA (1975)

<h3>In Reply.—</h3> Because of the demands of space, I will answer only Dr. Sussman's serious charges. 1. There has been a fairly large group of investigators in Long Beach working at the Long Beach Memorial Hospital for the past seven years. This accounts for the rather large number of patients in our series. Every patient received a very adequate trial of conservative therapy that usually included a period of traction in the hospital. The classical indications for laminectomy (or laminotomy, if you prefer) have been well established. When severe low back pain and sciatica of long duration are coupled with organic findings such as an abnormal myelogram, neurological changes, and elevation of the spinal fluid protein concentration, surgical intervention becomes necessary. Of course, at least 85% and probably as much as 95% of episodes of low back pain and sciatica will remit with or without treatment. There is, however, a
Concurrent radiation therapy and weekly docetaxel in elderly patients with oropharyngeal carcinoma
Authors: L. N. Minea, R. Anghel, L. Oprea, T. Georgescu, X. Bacinschi, I. Isacu, A. Tarlea
Journal: Journal of Clinical Oncology (2007)

16539 Background: Orofaringeal cancer is one frequent localization in developing countries like Romania. Our purpose is to evaluate the compliance and efficacy of concurrent weekly docetaxel and radiation therapy as definitive treatment for elderly patients with oropharyngeal carcinoma. Methods: 20 patients, over 65 years of age, with primary oropharyngeal cancer, who were treated with concurrent docetaxel and radiation therapy, were reported between January 2003 and December 2005. The distribution depending on stage was: stage II - 4 patients, stage III - 6 patients, stage IV - 10 patients (IV A - 7 patients and IV B - 3 patients). The total dose of radiotherapy was 70 Gy. Chemotherapy was delivered weekly and consisted in Docetaxel 20 mg/sqm. 4 more cycles of chemotherapy (docetaxel 75 mg/sqm day 1 and cisplatin 75 mg/sqm day 1 every three or four weeks according to hematologic tolerance) were administrated after concurrent radiochemotherapy. Results: Only 2 patients interrupted the radiochemotherapy due to related toxicities, especially acute grade III - IV mucositis. Grade III - IV hematological toxicities were observed in 5 patients, and grade III - IV mucositis in 4 patients. At the time of analysis 18 patients are alive and 11 of them are disease free. Conclusions: Concurrent weekly docetaxel and radiation therapy did not affect patients’ compliance to treatment; acute toxicities were in acceptable limits. Concurrent radio - chemotherapy was well tolerated and results and acute toxicities were comparable with younger patients. Elderly cancer patients should be offered optimal treatment depending on their functional status not on chronological age. No significant financial relationships to disclose.
Anticoagulant Therapy—1974
Authors: Stanford Wessler
Journal: JAMA (1974)

THE national impact of thrombosis should not be underestimated. Arterial thromboembolism is a major, if not the primary, contributor to the number 1 (acute myocardial infarction), number 3 (stroke), and the number 4 (renal) causes of death in the United States. In addition, thromboembolic episodes are frequently associated (either causally or as a complication) with rheumatic or atherosclerotic valvular diseases, arrythmias, congestive heart failure, and intimal damage in the carotid artery, the aorta-iliac region, and the arteries of the lower extremities. Some infections and severe blood dyscrasias also may be associated with arterial thrombosis. Venous thromboembolism causes approximately 300,000 patients annually to be hospitalized in the United States, of which more than 50,000 die. The cost of the hospitalization of the 250,000 survivors has been calculated to be approximately $750 million per year. These figures do not include the morbidity and cost for patients with venous thrombosis alone, nor the
Farm Worker Illness Following Exposure to Carbofuran and Other Pesticides-- Fresno County, California, 1998
Journal: JAMA (1999)

In California, suspected pesticide-related illnesses and suspected work-related illnesses and injuries are reportable conditions. On July 31, 1998, the Occupational Health Branch of the California Department of Health Services (CDHS) received a report from the California Department of Pesticide Regulation (CDPR) of a pesticide exposure incident in Fresno County involving 34 farm workers. CDHS investigated this incident by reviewing medical records of the 34 workers and interviewing 29. The findings indicated that the workers became ill after early reentry into a cotton field that had been sprayed with a cholinesterase-inhibiting carbamate pesticides
Reply
Authors: Helen A. Brough, Jean-Christoph Caubet, Angel Mazon, Diab Haddad, Marcel M. Bergmann, Jacqueline Wassenberg, Valentina Panetta, Rosalynd Gourgey, Suzana Radulovic, Maria Nieto, Alexandra F. Santos, Antonio Nieto, Gideon Lack, Philippe A. Eigenmann
Journal: Journal of Allergy and Clinical Immunology (2020)
THE INFLUENCE OF THE DWELLING IN THE DEVELOPMENT OF TUBERCULOSIS.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Trinucleotide Repeats in Neurogenetic Disorders
Authors: H. L. Paulson
Journal: Annual Review of Neuroscience (1996)

Trinucleotide repeat expansion is increasingly recognized as a cause of neurogenetic diseases. To date, seven diseases have been identified as expanded repeat disorders: the fragile X syndrome of mental retardation (both FRAXA and FRAXE loci), myotonic dystrophy, X-linked spinal and bulbar muscular atrophy, Huntington’s disease, spinocerebellar ataxia type 1, dentatorubral-pallidoluysian atrophy, and Machado-Joseph disease. All are neurologic disorders, affecting one or more regions of the neuraxis. Moreover, five of the seven (the last five above) are progressive neurodegenerative disorders whose strikingly similar mutations suggest a common mechanism of neuronal degeneration. In this article we discuss specific characteristics of each trinucleotide repeat disease, review their shared clinical and genetic features, and address possible molecular mechanisms underlying the neuropathology in each disease. Particular attention is paid to the neurodegenerative diseases, all of which are caused by CAG repeats encoding polyglutamine tracts in the disease gene protein.
La Cuenta*
Authors: J P Bramante
Journal: Annals of Internal Medicine (1994)

On Being a Doctor15 February 1994La Cuenta*John P. Bramante, MDJohn P. Bramante, MDCentral Peninsula General Hospital, Soldotna, AK 99669.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-4-199402150-00013 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail *Cuenta: a narrative or report; also a bill or the cost.“Cuentame (Tell me),” he said, and she did.She sat across from him. I sat to the side. She was 19 years old with long black frizzy hair, a sharp pointed nose, and thin painted lips. Her face betrayed the boney ridges and the labyrinth of cartilage that lay beneath. With the suppleness of youth, her floating skin was still smooth and her smile was wide and wild. She was tall for a Mapuche and her young breasts defined a proud figure beneath her one-size-too-small V-neck sweater.“Nineteen days,” ... Author, Article, and Disclosure InformationAffiliations: Central Peninsula General Hospital, Soldotna, AK 99669.Corresponding Author: Peninsula Internal Medicine, 206 Rockwell Avenue, Soldotna, AK 99669. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 February 1994Volume 120, Issue 4Page: 339KeywordsBloodCartilageFallsHappinessHeartHeart murmursHeart rateHemorrhagePregnancyStenosis Issue Published: 15 February 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
TOXICITY AND IDIOSYNCRASY.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Rheumatology
Authors: George E. Ehrlich
Journal: JAMA (1980)

When a syndrome or a disease is newly described, a question arises as to whether the disease is truly new or only newly recognized. The 1970s saw the emergence of such a disease, Lyme arthritis. No evidence suggests that it existed before 1965; it was discovered in 1975, investigated and described during the next five years, and, by the end of 1979, just about fully understood. Although the causative agent has not been isolated, the elucidation of Lyme arthritis represents one of the most fascinating pieces of detective work, by rheumatologists at Yale University.<sup>1-5</sup> A geographic clustering of children with relatively evanescent arthritis, originally thought to be juvenile rheumatoid arthritis by their physicians, drew attention to the small community of Lyme, Conn.<sup>4</sup>The attacks were recurrent and included monoarthritis, oligoarthritis, and even migratory arthritis. They seemed to leave no residua. Gradually, there emerged a history of a prior
Editorial: To lessen the impropriety
Authors: C. D. Aring
Journal: JAMA (1974)

IT IS the nature of things for a family beset with hopeless illness to seek endlessly for help. This is the more so when medical advice is lacking or relatives are uneasy about the assistance that has been proffered. The plight of patients with an incurable disease is saddening, but the milk of human kindness tends to curdle on finding them in the coils of the entrepreneur. It is disheartening to witness some of the things done to desperately ill people in the name of treatment. It is difficult for the physicians to maintain equanimity under these circumstances, and the indignity is compounded when quacks associate themselves, as they are wont to do, with heroic figures of the stamp of Semmelweis and Pasteur. To make of the dying a business requires a considerable titer of delusion or depravity. Our "Founding Father" was not referring to the desperately ill in the
Home transfusions of hemophiliacs
Authors: S. F. Rabiner
Journal: JAMA (1972)

We have had three years' experience with a home transfusion program for hemophiliacs. The group consisted of 36 patients, of which 32 had antihemophilic factor deficiency and 4 had plasma thromboplastin component deficiency. There were minimal technical problems and no serious transfusion reactions. Although there was an increase in the number of reported hemorrhages, there was a concomitant decrease in the number of hospital admissions. Of importance is the fact that there was a decrease in the number of severe orthopedic problems and days lost from school or work. Of equal importance was the psychological impact of home transfusion on patients and their families. This included a sense of self-reliance, an increase in mobility, and freedom from fear. The authors conclude that, until a prophylactic regimen is feasible, home transfusion is the treatment of choice for hemophilia.
Ureteral Tumors
Authors: V. L. Robards, Ian M. Thompson
Journal: JAMA (1964)

<h3>To the Editor:—</h3> Certainly we can offer no solution to the problem of classifying urothelial papillomas. One cannot predict in which individuals other urothelial tumors will develop. In the case mentioned by Dr. Bergman, could not the vesical lesion which occurred five years after removal of a noninvasive ureteral papilloma have been a subsequent primary lesion? Concerning the urographic findings in ureteral tumors, we wish to emphasize that the pyelographic findings are often not specific. To make a preoperative diagnosis of ureteral tumors one should have a high index of suspicion and should invariably outline the entire ureter at the time of retrograde urography. The variety of urographic findings pointed out by Dr. Bergman would appear to add support to this proposition. Certainly the prognosis in ureteral tumors is guarded; however, this should not necessarily justify nephroureterectomy on an empiric basis in every case. In our group of patients with
SPHENOID SAFETY BURR
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal