tbuckley/cabot-search huggingface dataset:
VIOSTEROL PREPARATIONS AND GALLSTONES
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Early thrombolytic treatment.
Journal: BMJ (1989)

them with a sample of patients who had had shingles but did not develop neuralgia.One of the findings was that the area of the residual scarring was considerably larger in those with post-herpetic neuralgia than in controls (p<0O001).2We there- fore suggest that measures that reduce-the residual scarring may reduce post-herpetic neuralgia.We know that acyclovir given early enough reduces the lesions during the severe attacks of shingles.'We agree with Dr Pamela Todd and Dr John Thomson4 that further studies are needed to look at the possible benefit of acyclovir in preventing post- herpetic neuralgia.Also, we suspect that the incidence of postherpetic neuralgia is falling.This proposition is supported by a recent study that found that the incidence was 13% at six months in patients over 605 and a study from 1957 that found an incidence of 83% in patients over 70.6If this is a true picture of the incidence of the disease and not a sampling error we suspect that it has declined because of a change in the virulence of the zoster virus.
Noninvasive measurement of hemoglobin saturation by visible reflectance hyperspectral imaging during nitric oxide inhibition and inhalation Karel J. Zuzak, Michael D. Schaeberle, Mark T. Gladwin, Richard O. Cannon, III, Ira W. Levin. National Institutes of Health, Bethesda, MD
Journal: Journal of the American College of Cardiology (2001)
Visualizing the Effect of Pentoxyphyllin Infusion Therapy on the Circulation of the Hand by Tc-99m DPTA Scintigraphy
Authors: ILDIKÓ GARAI, ZOLTÁN CSIKI, GABRIELLA SZÜCS, JÓZSEF VARGA, LÁSZLÓ GALUSKA
Journal: Clinical Nuclear Medicine (2003)

Raynaud's phenomenon, manifested in episodic, vasospasm- originated, three-phase changes in the color of the fingers, is often a concomitant phenomenon of several autoimmune diseases, such as systemic sclerosis. In such patients, the circulation of the fingers can be affected in different degrees, including cases with serious disorders of the microcirculation, which lead to ulcers on the finger and possibly amputation. Pentoxifylline therapy, which improves circulation, may be effective in such cases. Tc-99m DPTA perfusion imaging of the hand can objectively visualize the circulation of the fingers and measure the effectiveness of therapy.
Traité de pathologie médicale et de thérapeutique appliquée.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Insulin Antibodies in Pregnancy
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Goulstonian Lectures on the Natural History of Pulmonary Consumption
Authors: A. B. Shepherd
Journal: BMJ (1876)

I suppose, in every young nan's life when an idea-to himself seem- ingly a fresh one-stamps itself upon his mind as true, and therefore to be worked out to its full meaning.Such a timne occurred to my- self, when, one afternoon, I accompanied into one of his wards at Guy's hIospital the late Dr. Barlow, sometime Goulstonian Lecturer and Censor of this College.I had been working clinically and micro- scopically at cases of so-called-more commonly, perhaps, in that day than this-" tubercular phthisis".I remember asking him, with the audacityof a student, not always to be reprehended, what was the differ- ence between this " tubercular phthisis" and fatal cases of acute pneumonia, except in the much slower march of the former, and the absence, to a very large extent, in it of the pungent heat of skin always present in the latter.I told him that in both I had found what seemed to me very often to be the same microscopical appearances.hlis answer-the answer of one who had been a fellow-worker with Addison-was that he recognised their great similarity.The thermometer was then un- known ; and neither of us lhad in our minds cases of acute miliary tuberculosis, but cases only of acute primary lung-affection on the one side, and, oni the other, cases of chronic primary lung-disease.It needed but little later reading to learn the existence of a discussion- at that time even by no means new, by no means even yet satisfied-
Epidemic transmission of enterically transmitted non-A, non-B hepatitis in Mexico, 1986-1987
Authors: O. Velazquez
Journal: JAMA (1990)

Outbreaks of acute hepatitis occurred in Huitzililla and Telixtac, two rural villages 70 miles south of Mexico City, Mexico, in late 1986. The first outbreak began in Huitzililla in June of that year, 1 month after the start of the rainy season. A census revealed 94 icteric case subjects, for an attack rate of 5%; two women died. Attack rates were higher for persons older than 15 years (10%) than for younger persons. A case-control study showed that illness was highly associated with water-related factors. The second outbreak began in August 1986 in Telixtac. There were 129 case subjects, for an attack rate of 6%; one woman died. Epidemiologic findings were similar to those in Huitzililla, except that most disease transmission was not linked to unsafe water sources. None of 62 case subjects in Huitzililla and only 2 of 53 case subjects in Telixtac tested had serological evidence for recent infection with hepatitis A or B. Two of eight stool samples from Huitzililla and one of eight stool samples from Telixtac were positive by immune electron microscopy for 32- to 34-nm viruslike particles similar to those seen in cases of enterically transmitted non-A, non-B hepatitis from Asia. To our knowledge, these investigations document for the first time the epidemic transmission of enterically transmitted non-A, non-B hepatitis virus in the Americas. (<i>JAMA</i>. 1990;263:3281-3285)
Abstract 68: Echocardiographic Evaluation of the Kawasaki Disease Mouse Model
Authors: Aaron Olson, Dolena Ledee, Hidemi Kajimoto, Margaret Bruce, Michael Portman
Journal: Circulation (2015)

Background: Mouse echocardiography is an established, non-invasive method to evaluate experimental cardiovascular disease. The murine Kawasaki disease (KD) model demonstrates aortic and coronary artery inflammation by histology. The clinical relevance of these pathological changes has not been confirmed. In children, KD involves coronary artery abnormalities visualized by echocardiography. However, echocardiography has not been previously applied to the mouse KD model. We hypothesized that coronary vasculitis caused the lactobacillus casei cell wall extract (LCE) causes abnormalities detectable by echo. Methods: Male mice (ages 3-4 months) were injected with LCE or vehicle. Sedated echos were performed with a VisualSonics Vevo 2100 system. Twelve mice (8 LCE and 4 vehicle) had pre-injection echos followed by serial studies for 6-10 weeks. Evaluations were blinded to treatment group. 2-D measurements were taken at consistent locations in the arteries. Aortic regurgitation was rated based upon clinical criteria. Histology was evaluated at 6 weeks post-LCE. Results: Mild aortic regurgitation (AR) was present in 6 of 8 mice injected with LCE starting at 1 week post-injection. No AR was present at baseline or vehicle injected mice. LCE mice showed increased aortic root diameter at 6 weeks compared to baseline (1.78mm±0.01 vs 1.52±0.02, p&lt;0.05). Overall left coronary artery dimensions were not changed from baseline at 6 weeks post-LCE, but coronary imaging was difficult. One mouse had a diffusely enlarged left coronary system and severely diminished left ventricular function at 10 weeks post-LCE. Histology findings were present in all LCE-injected mice including aortic valvulitis, myointimal proliferation and a single case of infarction. Conclusion: The most prominent echo findings in the mouse KD model are severe aortitis with dilation and valvular regurgitation. These features could serve as non-invasive experimental measurements. Coronary dilation was a rare finding; however the coronaries are difficult to evaluate in mice. Overall, the mouse KD model demonstrates greater aortic pathology than found in human KD. Further studies are underway to evaluate additional non-invasive measurements such as vascular strain.
Abstract 2421: Iron deficiency suppresses EMT through down-regulation of N-cadherin in esophageal cancer.
Authors: Shinichiro Watanabe, Seishi Nishitani, Kazuhiro Noma, Toshiaki Ohara, Yasuko Tomono, Yuuri Hashimoto, Hiroshi Tazawa, Toshiyoshi Fujiwara
Journal: Cancer Research (2012)

Abstract [Introduction] Epithelial-Mesenchymal-Transition(EMT) plays a great role in cancer metastasis and invasion. Mechanism of EMT still remains unclear, However E-cadherin and N-cadherin are known to have contribution to EMT. In particular, down-regulation of N-cadherin has been reported to reduce cancer metastasis and invasiveness. Iron metabolism and its relationship with cancer cell were studied for a long time. Iron overload is known to induce some kinds of cancer, and iron deficiency is also known to suppress the tumor growth in vivo study. But the correlation of iron metabolism and tumor progression isn't unclear. Recently, it was reported that iron metabolism was essential for EMT and iron deficiency down-regulated EMT differentiation. In this study, we hypothesized that iron deficiency down-regulated the expression of N-cadherin, and suppressed the ability of metastasis and invasiveness. Here we demonstrate our results. [Materials and Methods] In vitro study, TE-4 and TE-10 esophageal squamous cell carcinoma and OE19 esophageal adenocarcinoma cell line were used in this study. Cell viability was determined by XTT assay. Iron chelator deferasirox was used to simulate iron deficient condition. To determine that iron deficiency suppresses EMT and invasiveness of cancer cells, we investigated western blotting analysis, three-dimensional spheroid model analysis and migration assay. Moreover, to determine the expression N-cadherin in mRNA level, PCR assay was performed. In vivo study, iron depletion condition was made by iron deficient diet. Normal and iron deficient diet were fed for 3 weeks before implantation of TE-4 cells in athymic male nude mice(n=8/group). After implantation, each diet was fed continuously for a month. [Results] In vivo study, iron deficient diet suppressed the tumor growth(tumor volume: normal diet vs iron deficient diet = 30.7±1.1 mm3 vs 10.9±2.2 mm3). In vitro study, deferasirox reduces proliferation of all cell lines in a concentration manner. According to western blotting analysis, deferasirox induces reduction of N-cadherin protein in TE-4 and TE-10 cell lines. N-cadherin down-regulation declines invasiveness of TE-4 and TE-10 cell lines in the three-dimensional spheroid model analysis and migration assay. Real time PCR assay shows that down-regulation of N-cadherin is dependent on reduction of N-cadherin mRNA. [Conclusion] Iron controlled treatment can be a novel therapy for invasiveness of cancer under EMT. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 2421. doi:1538-7445.AM2012-2421
Neuroscience
Authors: L. Politansky, M. Orsi, L. Saligari, L. Cácercs, A. Fernández, L. Albano, Susan L. Bratton, Robert L. Davis, L. Laho, K. Kralinský, S. Dluholucký, Z. Drobová, D. Martišová, J. Nosko, A. Palomeque, J. M. Costa, F. J. Cambra, C. Luaces, M. Pons, J. M. Martin, L. Tortorolo, A. Chiaretti, M. Piastra, L. Viola, G. Polidori, V. Zh. Muskalenko, E. P. Kumapov, I. V. Esimbalistova, V. K. Litovka, R. -D. Stenger, S. Mukodzi, P. Müller, -B. Beyer, S. Schmidt, H. Abdul-Khaliq, M. Vogel, P. Ewert, N. Nagdyman, P. E. Lange, F. Berger, I. Dähnert, J. H. Nürnberg, V. Modesto, E. Ibiza, A. Abengochea, J. Arago, R. Sanchis, R. Varas, R. Calderaro, J. Tomas, E. Garcia, Sunit Singhi, Sanjoy Banerjee, Pratbha Singhi, J. Krastins, F. Bordet, J. C. Berthier, B. Contamin, C. Pondarre, A. Rousson, A. van Esch, H. A. van Steensel-Moll, I. R. Ramlal, G. Derksen-Lubsen, I. D. F. Habbema, M. Reisoglou, S. Vassiliagou, A. Vaksevanidou, S. Folgado, A. Burguet, A. Menget, E. Monnet, A. Gasca-Avanzi, C. Fromentin, H. Allemand, J. Y. Pauchard, M. L. Dalphin, S. Burja, I. Kostovic, M. Judas, H. B. M. Uylings
Journal: Intensive Care Medicine (1996)
Surgical Memoir
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Congenital rubella syndrome in late infancy
Authors: S. A. Plotkin
Journal: JAMA (1967)

A group of 109 Philadelphia infants with congenital abnormalities presumably caused by rubella was analyzed for various features. Isolation data showed that only a few infants had virus present in the throat and cerebrospinal fluid by 1 year of age (9% and 4%, respectively). Recovery of virus from lens material obtained at surgery, however, was frequent, even in patients 18 months old. The neutralizing-antibody test was found useful in the retrospective diagnosis of rubella syndrome. A titer of 1:4 or greater in infants older than 6 months was 94% accurate in identifying intrauterine infection. The complement-fixation test was less useful.
Interplay between metabolic derangement, biomarkers of collagen remodeling and macrophage activation in non-diabetic patients with non-alcoholic fatty liver disease
Authors: Chiara Rosso, Ramy Younes, Diana Leeming, Rambabu Surabattula, Gian Paolo Caviglia, Melania Gaggini, Angelo Armandi, Antonella Olivero, Maria Lorena Abate, Amalia Gastaldelli, Detlef Schuppan, Elisabetta Bugianesi
Journal: Journal of Hepatology (2020)
A latter-day Tolstoi
Authors: A. Brass
Journal: JAMA (1970)

<i>The Cancer Ward</i>is not just another novel about a hospital, despite its standard cast of "character" patients, flirtatious nurses, and dedicated doctors. Rather it mirrors the whole of life in contemporary Russia, reflected from the mind of an intelligent, highly gifted writer. And it is, perhaps, ironic confirmation of Aleksandr Solzhenitsyn's success in accurately capturing that reflection that he has recently been expelled from the Soviet Writer's Union. In his earlier books,<i>One Day in the Life of Ivan Denisovitch and The First Circle</i>, Solzhenitsyn described life first in a Siberian prison camp and second in a special prison for technological experts during Stalin's reign of terror. Both novels were based on the author's own experience in such establishments after having been indiscreet enough to criticize Stalin in personal letters. For the framework of<i>Cancer Ward</i>, Solzhenitsyn similarly uses observations made while a patient in a hospital in Tashkent,
Cancer associated thrombosis: Which lessons for the hematologist?
Authors: Simon Noble
Journal: HemaSphere (2018)

Marie Curie Palliative Care Research Centre, Cardiff University, Cardiff Wales, UK This is an open access Abstract Book distributed under the Attribution-NonCommercial-NoDerivs (CCBY-NC-ND), which allows third parties to download the abstracts and share them with others as long as they credit the author and the abstract book, but they cannot change the content in any way or use them commercially. http://creativecommons.org/licenses/by-nc-nd/4.0
Clinical Neurology
Authors: Alexander T. Ross
Journal: JAMA (1964)

This book does not purport to be a comprehensive textbook of neurology. Rather, the author emphasizes that it is written as a guide for students and practitioners faced with the need to diagnose and treat common neurological disorders, leaving the rarer and more complicated problems to the specialist. Within this context Lord Brain has provided a lucid, readable, concise, and practical volume. This second edition, with minor revisions and up-dating, is similar to the first. The book is divided into five parts. Part I discusses disorders of function, and includes history-taking, the neurological examination, the interpretation of findings, ancillary investigations, disorders of consciousness, epilepsy, migraine, and headache. Part II discusses disorders in respect to anatomical regions— the brain, spinal cord, peripheral nerves, and muscles. Part III presents the common infections of the nervous system and Part IV a discussion of disorders affecting the nervous system in a diffuse or systemic
FLIES AND TYPHOID FEVER.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Antibody to hepatitis-associated antigen. Frequency and pattern of response as detected by radioimmunoprecipitation
Authors: H. J. Lander
Journal: JAMA (1972)

Serum samples from a human population group in the Washington, DC, area and from a chimpanzee colony in Arizona were tested for antibody to hepatitis-associated antigen (anti-HAA) by the redioimmunoprecipitation technique. Anti-HAA was detected in 64 of 324 (20%) persons tested; an age-specific increase in frequency and geometric mean titer of anti-HAA was observed. There was no difference in frequency between males and females. Forty-six of 81 chimpanzees tested were found to have anti-HAA; the frequency of this antibody also increased with age. IgM and IgG anti-HAA were measured in ten patients who developed anti-HAA after what was thought to be primary exposure to HAA. IgM and IgG anti-HAA were detected in all ten patients. No specific patterns of IgM or IgG anti-HAA response were detected.
Continuing medical education
Authors: M. E. Johnson
Journal: JAMA (1983)

<h3>Physician's Recognition Award</h3> An important event in continuing medical education (CME) in 1983 was the publication and distribution of the new information booklet for the American Medical Association Physician's Recognition Award (PRA). This new edition presents an innovative rearrangement of the material by dividing it into two parts. The first part contains information for physicians who wish to complete the PRA application. The second part contains information for organizations and institutions providing CME programs. This division expedites the use of the information booklet for the physician user or a program provider that is seeking information about the policies and procedures associated with the award. Most of the material was completely rewritten to bring it up to date and to provide clarification. A valuable addition to the booklet is the inclusion of an abridged section of Report A of the Council on Medical Education, which was adopted by the AMA House