tbuckley/cabot-search huggingface dataset:
Abstract 456: Increasing the Compression Velocity and Acceleration Improved the Quality of Simulated Chest Compression Under the Direction of Real Time Visual Feedback Device
Authors: Yu Cao, Yarong He, Peng Yao
Journal: Circulation (2019)

Background: To investigate whether a real-time visual feedback device could improve the quality of chest compression (CC), and, if so, whether the mechanism is associated with dynamic indexes such as velocity and acceleration. Methods: A self-control trial of 2-minutes CC on a manikin by trained rescuers compared the quality of CC without or with a visual feedback device. Demographic characteristics were recorded and CC metrics for the two tests were computed. Multivariable linear regression analyses were performed to examine the impact of variables on rate of qualified chest compression (RQCC). Multivariable logistic regression was performed to determine independent risk factors for achieving qualified chest compression (QCC) in the second test. Results: A total of 159 participants (average age: 29.36±9.0 years, 80 (50.3%) men) were recruited. RQCC of the second test was significantly greater than that of the baseline test. Multivariable linear regression analysis showed that maximum compression velocity (V compression ) and maximum compression velocity (a compression ) were independent risk factors for RQCC for both tests. The mean V compression and a compression of the second test were significantly greater than those of the baseline test. However, V compression was the only independent risk factor predicting QCC achievement during the second test. ROC curve analysis showed the area under curve (AUC) was0.84,and the optimal cut-offvalue ofV compression was 39.48 cm/s. Conclusions: Increasing the V compression and a compression might improve the quality of simulated CC and should be recommended to improve QCC. Only V compression was an independent risk factor for achieving QCC during CC with a visual feedback device.
Table of Contents
Authors: Kamyar Kalantar-Zadeh, Kam-Tao Li, Ekamol Tantisattamo, Latha Kumaraswami, Vassilios Liakopoulos, Siu-Fai Lui, Ifeoma Ulasi, Sharon Andreoli, Alessandro Balducci, Sophie Dupuis, Tess Harris, Anne Hradsky, Richard Knight, Sajay Kumar, Maggie Ng, Alice Poidevin, Gamal Saadi, Hans-Joachim Anders, Yutian Lei, Brad Rovin, Alessandro Luciani, Massimiliano Stagi, Ellen Ginzler, Katherine Tuttle, David Cherney, Jonathan Hogan, Dan Vogl, Alastair Rankin, Patrick Mark, James Burton, John Mahan, Mahmoud Kallash, William Smoyer, Antonio Gargiulo, Laura Massella, Barbara Ruggiero, Lucilla Ravà, Marta Ciofi, Marco Atti, Francesca Materassi, Elisa Lugani, William Benetti, Daniela Morello, Francesca Molino, Marco Mattozzi, Silvio Pennesi, Andrea Maringhini, Bruno Pasini, Carmine Gianoglio, Giovanni Pecoraro, Luisa Montini, Gian Murer, Paola Ghiggeri, Marina Romagnani, Francesco Vivarelli
Journal: Kidney International (2021)
Double-Blind, Placebo-Controlled Comparison of Imipramine and Paroxetine in the Treatment of Bipolar Depression
Authors: C. B. Nemeroff
Journal: American Journal of Psychiatry (2001)

OBJECTIVE: This study compared the efficacy and safety of paroxetine and imipramine with that of placebo in the treatment of bipolar depression in adult outpatients stabilized on a regimen of lithium. METHOD: In a double-blind, placebo-controlled study, 117 outpatients with DSM-III-R bipolar disorder, depressive phase, were randomly assigned to treatment with paroxetine (N=35), imipramine (N=39), or placebo (N=43) for 10 weeks. In addition to lithium monotherapy, patients may have received either carbamazepine or valproate in combination with lithium for control of manic symptoms. Patients were stratified on the basis of trough serum lithium levels determined at the screening visit (high: >0.8 meq/liter; low: ≤0.8 meq/liter). Primary efficacy was assessed by change from baseline in scores on the Hamilton Rating Scale for Depression and the Clinical Global Impression illness severity scale. RESULTS: Differences in overall efficacy among the three groups were not statistically significant. For patients with high serum lithium levels, antidepressant response at endpoint also did not significantly differ from placebo. However, both paroxetine and imipramine were superior to placebo for patients with low serum lithium levels. Compared to imipramine, paroxetine resulted in a lower incidence of adverse events, most notably emergence of manic symptoms. CONCLUSIONS: Antidepressants may not be useful adjunctive therapy for bipolar depressed patients with high serum lithium levels. However, antidepressant therapy may be beneficial for patients who cannot tolerate high serum lithium levels or who have symptoms that are refractory to the antidepressant effects of lithium.
Reports of the Committee Upon the Physiology of Vision. XI. Individual Differences in Normal Colour Vision: A Survey of Recent Experimental Work (1910-31).
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Outbreak of Mycobacterium chelonae infection associated with use of jet injectors
Authors: J. D. Wenger
Journal: JAMA (1990)

Between January 1 and May 15, 1988, foot infections due to<i>Mycobacterium chelonae</i>subspecies abscessus were diagnosed in eight persons who had undergone invasive procedures at a podiatry office. A cohort study was performed to evaluate risk factors for disease. Persons who underwent procedures before 10:30 AM were more likely to have developed infection than those with procedures after that time (relative risk, 5.6). In addition, procedures involving any of the second through fourth toes were more likely to have resulted in infection than procedures involving only the first and/or fifth toes (relative risk, 4.4). Persons with 0, 1, or 2 risk factors had attack rates of 5%, 14%, and 60%, respectively.<i>Mycobacterium chelonae</i>subspecies abscessus organisms of the same antimicrobial resistance pattern as the patients' strains were cultured from distilled water in a reusable, nonsterilized container. A jet injector used to administer lidocaine was held between procedures in a mixture of the distilled water and a disinfectant as recommended by the manufacturer. Inoculation of patients with mycobacteria by the jet injector may have only occurred early in the day due to slow killing of the bacteria by the disinfectant. The outbreak emphasizes the pathogenicity of this water-associated organism and the need for high-level disinfection of jet injectors. (<i>JAMA</i>. 1990;264:373-376)
Conference on Breast Cancer: A Report to the Profession, 1976
Journal: JNCI Journal of the National Cancer Institute (1976)

Journal Article Conference on Breast Cancer: A Report to the Profession, 1976 Get access JNCI: Journal of the National Cancer Institute, Volume 57, Issue 2, August 1976, Pages 459–460, https://doi.org/10.1093/jnci/57.2.459-d Published: 01 August 1976
Contents
Authors: M Brunetto, P Marcellin, B Cherubini, C Yurdaydin, P Farci, S Hadziyannis, V Rothe, L Regep, F Bonino, S Lejamtel, B Battaglia, B Testoni, C Benassi, L Gondeau, C Perrin-Cocon, V Desterke, D Thiers, M Samuel, C Levrero, M.-F Bre, S Petta, G Marchesini, L Caracausi, F Macaluso, C Camma, S Ciminnisi, D Cabibi, R Porcasi, A Craxı, V Di, G Van Rijckevorsel, J Whelan, M Kretzschmar, E Siedenburg, G Sonder, R Geskus, R Coutinho, A Van Den Hoek, M Simo ´n-Talero, R Garcı ´a-Martı ´nez, M Torrens, S Augustin, S Go ´mez, G Pereira, M Guevara, P Gine, G Soriano, E Roma ´n, J Sa ´nchez-Delgado, R Ferrer, J Nieto, P Sunye, I Fuentes, R Esteban, J Co ´rdoba, M Rodrı ´guez-Pera ´lvarez, E Tsochatzis, M Naveas, G Pieri, C Garcı ´a- Caparro, J Oõbeirne, A Poyato-Gonza ´lez, G Ferrı ´n-Sa ´nchez, J Montero- A ´lvarez, D Patch, D Thorburn, J Bricen, M De La Mata, A Burroughs, B Ke, X.-D Shen, Y Zhang, H Ji, F Gao, S Yue, N Kamo, Y Zhai, M Yamamoto, R Busuttil, J Kupiec-Weglinski, M Jime ´nez-Castro, A Casillas-Ramı ´rez, M Mendes-Braz, M Massip- Salcedo, M Elias-Miro, J Kim, C Kwon, J.-W Joh, E.-S Kang, J Park, J Lee, S Kim, S Paik, S.-K Lee, D Kim, L Barbier, S Garcia, J Cros, P Borentain, D Botta-Fridlund, V Paradis, Y.-P Le Treut, J Hardwigsen, C Verhoeven, W Farid, P De Ruiter, B Hansen, H Roest, J De Jonge, J Kwekkeboom, H Metselaar, H Tilanus, G Kazemier, L Van Der Laan, T Kawaguchi, T Kodama, H Hikita, S Tanaka, M Shigekawa, T Nawa, S Shimizu, W Li, T Miyagi, N Hiramatsu, T Tatsumi, T Takehara, M Kohjima, T.-H Tsai, B Tackett, S Thevananther, L Li, J Chang, L Chan, D.-X Guan, J Shi, H Gao, J.-J Li, J.-S Zhao, L Qiu, J Liu, N Li, W.-X Guo, J Xue, F.-G Zhou, M.-C Wu, H.-Y Wang, D Xie, S.-Q Cheng, M Ziol, A Sutton, J Calderaro, N Barget, M Aout, V Leroy, J.-F Blanc, N Sturm, P Bioulac-Sage, P Nahon, J.-C Nault, N Charnaux, G Nõkontchou, J.-C Trinchet, M Delehedde, O Seror, M Beaugrand, E Vicaut, N Ganne-Carrie, R Finn, R Poon, T Yau, H.-J Klu ¨mpen, L.-T Chen, Y.-K Kang, T.-Y Kim, C Gomez-Martin, C Rodriguez-Lope, T Kunz, T Paquet, U Brandt, D Sellami, J Bruix, A Wannhoff, J Hov, T Folseraas, C Rupp, K Friedrich, J Anmarkrud, K Weiss, P Sauer, P Schirmacher, K Boberg, W Stremmel, T Karlsen, D Gotthardt, G Cheng, S.-M Tang, .-M Wong, -C Cheng, M.-T So, X Miao, R Zhang, L Cui, X Liu, -W Ngan, -H Lui, -Y Chung, -Y Chan, W Zhong, H Xia, J Yu, X Qiu, X.-Z Wu, B Wang, X Dong, J Tou, L Huang, B Yi, H Ren, -W Chan, K Ye, P O¢reilly, -Y Wong, P.-C Sham, S Cherny, -H Tam, M.-M Garcia-Barcelo, K Chaudhary, C Liedtke, S Wertenbruch, C Trautwein, K Streetz, Y Cao, Y Xue, L Xue, X Jiang, X Wang, Z Zhang, J Yang, J Lu, C Zhang, W Wang, G Ning, N Nativ, G Yarmush, A Chen, D Dong, S Henry, J Guarrera, K Klein, T Maguire, R Schloss, F Berthiaume, M Yarmush, A Moschen, V Wieser, R Gerner, A Bichler, B Enrich, P Moser, C Ebenbichler, S Kaser, H Tilg, M Romero-Go ´mez, M Berenguer, E Molina, J Calleja, M Zeybel, D Mann, J Mann, A Sehgal, K Vaishnaw, T Fujita, A Zignego
Journal: Journal of Hepatology (2013)
<i>QuickStats:</i> Birth Rates* for Teens Aged 15–19 Years, by State — National Vital Statistics System, United States, 2018
Journal: MMWR Morbidity and Mortality Weekly Report (2019)

4 7.2-12.9DC Abbreviation: DC = District of Columbia.* Births per 1,000 females aged 15-19 years.The 2018 U.S. rate was 17.4 births per 1,000 females aged 15-19 years.In 2018, the U.S. birth rate for teens aged 15-19 years was 17.4 births per 1,000 females, with rates generally lower in the Northeast and higher across the southern states.Teen birth rates ranged from 7.2 in Massachusetts, 8.0 in New Hampshire, 8.3 in Connecticut, and 8.8 in Vermont to rates of 30.4 in Arkansas, 27.8 in Mississippi, 27.5 in Louisiana, 27.3 in Kentucky, and 27.2 in Oklahoma.
Melioidosis.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contents of Volume 91, Numbers 1-6
Authors: Michael Lemp, H Blackman, Louis Wilson, Albert Leveille, Richard Forster, Toxoplasmic Papillitis, James Folk, Louis Lobes, John Keltner, Chris Johnson, Serge De Bustros, Robert Welch, Jean Holt, G Holt, Marion Kirk, Fasclocutaneous Flap, Bahman Guyuron, Harold Labandter, A Berlin, Joseph Mauriello, Joseph Flanagan, Robert Peyster, J Rathbun, Kenneth Noble, Paul Henkind, Robert Feder, Jay Krachmer, Mark Haimann, Gary Abrams, George Blankenship, Mark Blumenkranz, Eleut Hernandez, Avinoam Ophir, Edward Norton, Walter Stern, Alan Cruess, James Augsburger, Jerry Shields, Larry Donoso, Jonathan Amsel, Frederick Jakobiec, Mary Depot, John Kennerdell, William Shults, Richard Anderson, Melvin Alper, Charles Citrin, Edgar Housepian, Stephen Trokel, In Detachment, Gholam Peyman, Mahmood Mafee, Joel Schulman, David Knox, Andrew Schachat, Eila Mustonen, Robert Coles, Lawrence Hirst, Evan Farmer, W Green, Allan Silver, Frank Walsh, Lars Fris{m, Christian Blomstrand, Roy Beck, Robert Sergott, Charles Barr, William Annesley, James Wise, Joe Hollyfield, Jeanne Frederick, Gareth Tabor, Robert Ulshafer
Journal: Ophthalmology (1984)
Conventional RIA underestimates cortisol suppression in the presence of prednisolone
Authors: B J Lipworth
Journal: Thorax (2002)

GM-CSF therapy in pulmonary alveolar proteinosisTreatment with granulocyte-macrophage colony stimulating factor (GM-CSF) has been shown to benefit a subset of patients with adult pulmonary alveolar proteinosis (PAP).A 47 year old woman with PAP, confirmed by lung biopsy, and severe physiological and symptomatic disturbances was not improved by repeated unilateral whole lung lavages.Six months after the last lavage we started treatment with daily subcutaneous GM-CSF in increasing doses beginning at 3 µg/kg.When a daily dose of 6 µg/kg was reached a haematological response was detected and dose escalation ceased.After 4 weeks at this dose the patient began to improve.By week 11 at a dose of 6 µg/kg/day the treatment was stopped and after a further 3 weeks without treatment she attained maximal clinical, radiological, and physiological improvement (from arterial oxygen tension (PaO 2 ) 6.1 kPa, alveolar-arterial oxygen gradient ((A-a)O 2 ) 8.2 kPa, total lung capacity (TLC) 63.3%, and carbon monoxide transfer factor (TLCO) 58.7% at diagnosis to 10.9 kPa, 2.6 kPa, 99%, and 101.1%, respectively).At that point, as the haematological parameters were normal, we decided empirically to restart treatment at a maintenance dose of 3 µg/kg/day twice a week to avoid relapse.Five months later, with no evidence of clinical deterioration or haematological response, treatment was stopped and after a further 18 months the patient remains symptom free.The successful remission of our patient, the seven published cases of GM-CSF in the treatment of PAP, 1-3 and the low incidence of side effects compared with the whole lung lavage technique prompt us to recommend GM-CSF as a first line treatment option in these patients.
Cost-containment efforts
Authors: R. C. Bryant
Journal: JAMA (1981)

<h3>To the Editor.—</h3> The effects of a voluntary cost-containment effort on the use of high-cost laboratory tests, roentgenograms, medications, and supplies in the emergency department of a community hospital have been described recently by Stephen Karas, Jr, MD (1980;243:1356). He reported a 10.2% reduction in aggregate charges for laboratory and radiology services. For each item in Karas' table, we looked at the percentage change frombaseline. Such values apply equally, of course, to either frequencies or costs, given constant unit cost. Certain items in Karas'study were "specifically emphasized as potential cost-cutting items." The Table shows, for laboratory and radiology items, the results of our analysis comparing these items with the remaining items (the reduced use of which had been stressed but not so strongly). An appreciable overall decrease for specifically emphasized items was countered by an overall increase for other items. Specific emphasis on a limited number of items was
Role of Cytochrome P-450 and Related Enzymes in the Pulmonary Metabolism of Xenobiotics
Authors: Richard M. Philpot, Brian R. Smith
Journal: Environmental Health Perspectives (1984)

The lung metabolizes a wide variety of xenobiotics and, in the process, forms products that may be more or less toxic than the parent compound. The consequence of metabolism, activation or detoxication, is a function of the nature of the substrate and of the characteristics and concentrations of the enzymes involved. As a result, the biotransformation of xenobiotics can lead to their excretion or to the formation of reactive products that produce deleterious effects by binding covalently to tissue macromolecules. Among the enzymes that metabolize xenobiotics, those associated with the cytochrome P-450-dependent monooxygenase system are probably the most important. The route by which a given substrate is metabolized in a tissue or cell is, to a great extent, determined by the types and concentrations of cytochrome P-450 isozymes present. We are just beginning to understand the distribution of these enzymes in lung and to appreciate the species and cellular differences that exist.
THE REGENERATION OF LIMBS.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
<i>Die Trinkerasyle Englands und die projectirte Trinkeranstalt fuer Niederoesterreich vom Standpunkte der Administration.</i>Von Fedor Gerenyi, Inspector beim niederoesterreichischen Landesausschuss. [English Inebriate Asylums, and the proposed Inebriate Asylum of Nether-Austria. By Fedor Gerenyi.]
Journal: American Journal of Psychiatry (1893)
Transactions of the New York Pathological Society for 1891.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Thyroid Gland in Pregnancy
Authors: Irwin M. Freedberg, Milton W. Hamolsky, A. Stone Freedberg
Journal: New England Journal of Medicine (1957)

THE purpose of this progress report is to review the present status of knowledge of thyroid-gland function in pregnancy; to discuss recent studies utilizing newer investigative technics to refocus interest in, and advance understanding of, the interrelation of normal and abnormal thyroid-gland function in pregnancy; and to evaluate the possible contribution of such observations of nature's "grandest experiment" to the knowledge of thyroid physiology and disease.Thyroid Function in Normal and Abnormal PregnanciesAnatomic and Histologic StudiesA relation between the thyroid gland and the female sex glands was appreciated by the ancients, who noted an increase in goiter formation . . .
Understanding the Core Result of the National Lung Screening Trial
Authors: Sumeet Asrani, A Carole, S Patrick
Journal: New England Journal of Medicine (2013)

notices(chemoembolization). Liver transplantation is limited by cardiac function (hypoxemia, pulmonary hypertension, and elevated right atrial pressure).Combined heart and liver transplantation may be feasible, but experience in such cases is limited. 5Since corrective surgery for patients with univentricular physiology has substantially reduced childhood mortality associated with complex cyanotic congenital heart disease, urgent attention and vigilance are needed to avoid a similar premature fate in early adulthood.