tbuckley/cabot-search huggingface dataset:
&lt;TITLE&gt;Benefits of Physical Activity for the Heart&lt;/TITLE&gt;
Journal: JAMA (2001)

information and recommendations appearing on this page are appropriate in most instances, but they are not a substitute for medical diagnosis.For specific information concerning your personal medical condition, JAMA and the AMA suggest that you consult your physician.This page may be reproduced noncommercially by physicians and other health care professionals to share with patients.Any other reproduction is subject to AMA approval.
Oncology Research Program
Authors: Theodoros Teknos
Journal: Journal of the National Comprehensive Cancer Network (2012)

Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or stopping them from dividing.Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells.Giving vorinostat together with chemotherapy and radiation therapy may kill more tumor cells.This phase I trial is studying the side effects and best dose of vorinostat when given together with cisplatin and radiation therapy in treating patients with advanced laryngeal, hypopharyngeal, nasopharyngeal, and oropharyngeal squamous cell carcinoma (SCC) of the head and neck.Primary Objective:• Determine the MTD of vorinostat in combination with concurrent chemoradiotherapy for the treatment of advanced stage laryngeal, hypopharyngeal, nasopharyngeal, and oropharyngeal SCC Secondary Objective:• Determine the complete response rate, overall survival, and progression-free survival using the MTD of vorinostat Tertiary Objectives:• Assess treatment-related acute and late toxicities when combining vorinostat with chemoradiation, and correlate these toxicities to molecular markers of apoptosis in tumor and normal oral mucosa • Evaluate the effect of vorinostat on tumor immune surveillance, particularly in HPV-positive patients • Illustrate that vorinostat alters the methylation status of commonly methylated genes in laryngeal, hypopharyngeal, nasopharyngeal, and oropharyngeal SCC
Physiological Genomics Identifies Estrogen-Related Receptor α as a Regulator of Renal Sodium and Potassium Homeostasis and the Renin-Angiotensin Pathway
Authors: Annie M. Tremblay, Catherine R. Dufour, Majid Ghahremani, Timothy L. Reudelhuber, Vincent Giguère
Journal: Endocrine Reviews (2009)

Estrogen-related receptor α (ERRα) is an orphan nuclear receptor highly expressed in the kidney, an organ playing a central role in blood pressure regulation through electrolyte homeostasis and the renin-angiotensin system. Physiological analysis revealed that, relative to wild-type mice, ERRα null mice are hypotensive despite significant hypernatremia, hypokalemia, and slight hyperreninemia. Using a combination of genome-wide location analysis and expression profiling, we demonstrate that ERRα regulates the expression of channels involved in renal Na+ and K+ handling (Scnn1a, Atp1a1, Atp1b1) and altered in Bartter syndrome (Bsnd, Kcnq1). In addition, ERRα regulates the expression of receptors implicated in the systemic regulation of blood pressure (Ghr, Gcgr, Lepr, Npy1r) and of genes within the renin-angiotensin pathway (Ren1, Agt, Ace2). Our study thus identifies ERRα as a pleiotropic regulator of renal control of blood pressure, renal Na+/K+ homeostasis, and renin-angiotensin pathway and suggests that modulation of ERRα activity could represent a potential avenue for the management of hypertension.
A Review of Approaches to the Detection of Genetic Damage in the Human Fetus
Authors: Richard B. Everson
Journal: Environmental Health Perspectives (1987)

Studies in experimental animals suggest links between genetic damage to the fetus and the etiology of several disorders, including fetal loss, teratogenesis, and cancer. Methods for measuring genetic damage directly in the human fetus could provide epidemiologists and clinical researchers with powerful tools for investigating similar associations in humans. Current methods potentially available for such studies include assays for mutagenic substances in human body fluids and for measuring modifications to genetic material at the three levels of organization of genetic material: the chromosome, the gene or specific locus, and chemical DNA. Results of studies using fetal tissues to investigate each of these end points are reviewed, emphasizing studies of chemical modifications to DNA nucleotides detected in the human placenta.
SATIRE
Authors: James Ransom
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review Epilepsy and Cerebral Localization: A Study of the mechanism, treatment and prevention of epileptic seizures . By Wilder Penfield, M.D., D.Sc. (Oxon., Princeton) and Theodore C. Erickson, M.Sc., M.D., with a chapter by Herbert H. Jasper and one by M. R. Harrower-Erickson. 4°, cloth, 623 pp., with 163 illustrations and 17 tables. Springfield, Illinois: Charles C Thomas, 1941. $8.00.
Journal: New England Journal of Medicine (1942)
Biochemical Abnormalities during Renal Insufficiency
Authors: Stanley E. Bradley
Journal: New England Journal of Medicine (1946)

Calcium and Phosphorus Calcium and phosphorus are predominantly localized in bone, but both elements occur in the cell,8 phosphorus being particularly important. Inorganic phosphate is the chief anion in the intracellular fluid, and the organic phosphates of the cell appear to have considerable significance in the metabolism of fats and carbohydrates, the energetics of cellular activity and the physiology of muscular contraction. The extracellular water content of calcium and phosphorus is small in absolute amounts, but it is vital in the maintenance of normal neuromuscular irritability and bone structure. In addition, both substances play a role in acid–base regulation of . . .
The Psychiatrist's View of Reaction to Stress
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Bearing witness
Authors: Toby Elkington
Journal: BMJ (2008)

Growth of fibroblasts from bronchoalveolar lavage fluid (BALF) in patients with systemic sclerosis (SSc) has previously been described. The purpose of the present study was to characterise fibroblasts from BALF and bronchial biopsies from SSc patients with alveolitis and from controls, to analyse fibroblast proliferation, migration, stress fibres and proteoglycan production. BALF and bronchial biopsies were collected from 10 patients with SSc and alveolitis and from 15 controls. Outgrowth of fibroblasts was observed from the BALF of four patients, particularly in those with a markedly increased percentage of eosinophils in BALF, but not in any member of the control group. Increased levels of granulocyte-macrophage colony-stimulating factor, correlating with the percentage of eosinophils in BALF, were found in patients when compared with controls. Fibroblasts from BALF showed an elongated, mobile phenotype and increased proteoglycan production compared to the corresponding biopsy fibroblasts. In conclusion, outgrowth of fibroblasts with an altered phenotype is reported from bronchoalveolar lavage fluid in systemic sclerosis patients with alveolitis and an increased percentage of eosinophils in the bronchoalveolar lavage fluid. These findings indicate a possible role for eosinophil–fibroblast interaction in pulmonary fibrosis in systemic sclerosis.
Correction
Journal: British Journal of Sports Medicine (2013)

In the section 'ZINC MONOMETHIONINE ASPARTATE', the second sentence is missing in the published version.The second sentence should be:The original product is composed of Zn (∼30 mg/serving), magnesium (∼450 mg/serving) and vitamin B6 (∼11 mg/serving), with many other companies promoting their own versions with added proprietary blends that claim to improve uptake and activity.
Judicial Council
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Risk Register.
Journal: BMJ (1967)

In a recent assessment of the merits of the various con- tenders for priority, F. C. Ormerod5 considers that Brown Kelly and Paterson have the edge on their rivals.This would appear to be confirmed by the relative frequency with which doctors on both sides of the Atlantic refer to the various authors concerned.J. Waldenstrbm6 emphasized that a low level of iron in the plasma (sideropenia) rather than anaemia was a basic feature of the syndrome.He described a woman with post- cricoid dysphagia, but who was not anaemic, whose dysphagia was cured by iron.Other manifestations of iron deficiency, such as soreness of the tongue and fissures at the corners of the mouth, which were present in this patient, were also cured by the iron therapy.Waldenstr6m suggested that the formation of a postcricoid " web " (which is shown by a barium swallow) and the dysphagia were due to iron deficiency, and subsequently this association has been recog- nized frequently.For example, R. Wright' was able to show in one patient that a low level of iron in the plasma had been present for eight months before the onset of dysphagia.At p. 281 of this week's B.M.7.
JICC01.14 Efficacy and Safety of Pralsetinib in Chinese Patients with Advanced RET Fusion+ Non-Small Cell Lung Cancer after Platinum-Based Chemotherapy
Authors: Q. Zhou, Y. Wu, J. Chang, Y. Fan, J. Zhao, G. Wu, Y. Sun, X. Wang, W. Nian, K. Wang, X. Zheng, L. Qu, S. Yao, K. Liu, P. Li, J. Yang
Journal: Journal of Thoracic Oncology (2021)
Glucose-6-Phosphate Dehydiogenase Deficiency and Neonatal Jaundice in Nigeria
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Materia Medica, Therapeutics, Medical Pharmacy, Prescription-Writing, and Medical Latin. A Manual for Students and Practitioners.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Editorial Board
Authors: Daniel Cattran, P Coates, Andrew Davenport, Tilman Drueke, Paris Ckd, Associated Complications, Masaomi Nangaku, Jai Radhakrishnan, New York, Maria Rastaldi, W Reeves, San Antonio, Detlef Schlöndorff, Michael Ross, Qais Al-Awqati, York New, Christina Wyatt, Vic Hasselblad, Jacksonville Zhezhen, Joseph Kim, Yi-Ju Li, , Durham, Dorothea Nitsch, London Ramakrishnan, Anupam Agarwal, Hans Anders, Jonathan Barratt, Daniela Leicester, São Barreto, David Paulo, Tomas Basile, Francois Denver, Joseph Berthoux, Emmanuel Boston, São Burdmann, Giovambattista Paulo, Christos Napoli, Yi-Pu Paris, Erik Chen, Steven Christensen, New Coca, Terence York, London Cook, D Vivette, New Agati, Farhad York, John Danesh, Ian Chicago, Marc De Boer, Antwerp De Broe, Vikas Zurich, St Dharnidharka, Zheng Louis, Adriana Dong, Kai-Uwe Oviedo, Erlangen Eckardt, Eiam-Ong Somchai, Michael Emmett, Dallas Endre, Sydney Evan, Pieter Evenepoel, Sarah Leuven, Denver Faubel, Steven Faul, Danilo Mineola, Jürgen Homburg, Agnes Aachen, Alessia Nashville, Barry Miami, Winston-Salem Freedman, Isehara Masafumi Fukagawa, Vesna Garg, Rochester Garovic, Laguna Glassock, Glenda Niguel, David Gobe, New Goldfarb, Matthew York, Mark Griffin, Angeles Haas, John Haase, Cijiang He, Michelle Hladunewich, Thomas Hostetter, Chi-Yuan Cleveland, San Hsu, Tobias Francisco, Benjamin Huber, St Humphreys, Reiko Louis, Jula Tokyo, Dallas Inrig, Francisco Kirsten Johansen, Roberto Kamyar Kalantar-Zadeh, Iowa Kalil, Yashpal City, Chicago Kanwar, New Kaskel, Krzysztof York, York Kiryluk, Clayton Kitching, Matthias Kopp, Ann Kretzler, Christian Arbor, Christophe Bonn, Paris Legendre, Los Lemley, Adeera Angeles, Philip Levin, Hong Li, Christoph Kong, John Toronto, Rochester Lieske, Jiannong Little, Kathleen Liu, San Liu, Youhua Francisco, Zhi-Hong Liu, Nanjing Liu, Dallas Lu, Matthias Berlin, Johannes Mack, Peter Mann, Hamilton Margetts, Kunihiro Amiens, William Matsushita, Atlanta Mcclellan, Timothy Mehrotra, Palo Meyer, Jeffrey Alto, St Miner, William Louis, Houston Mitch, Jeremiah Moeller, St Morrissey, Rosa Louis, São Moysés, Rama Paulo, Peter Duarte, David Nelson, Clayton Nikolic-Paterson, Klaus Charlottesville, Juan Oliver, York Charles O'neill, Atlanta Panzer, Mark Perazella, New Haven, Janos Peti-Peterdi, Los Angeles, Laura Plantinga, Atlanta Pollak, Didier Boston, Ambra Charlottesville, Susan Pozzi, Chicago Quaggin, Jochen Reich, Giuseppe Reiser, Sharon Bergamo, Mariano Clayton, Mitchell Rodriguez, Robert Rosner, Simone Safirstein, New Sanna-Cherchi, Antonio York, Kai Santoro, New Schmidt-Ott, Kumar York, La Sharma, Edward Jolla, Katalin Siew, Philadelphia Susztak, C Sydney, Hong Tang, Ravi Kong, Joshua Boston, Jens Denver, Marcello Nashville, Frank Tonelli, Manjeri Van Der Sande, San Venkatachalam, Carsten Antonio, Joel Wagner, Ann Weinberg, Matthew Arbor, Donald Weir, Temple Wesson, Jack Westenfelder, Adam Wetzels, Myles Whaley-Connell, Keng-Thye Durham, Kwan-Dun Woo, Taiwan Wu, Yusuke Suzuki, Tokyo Zeisberg
Journal: Kidney International (2016)
Continuing Education Opportunities for Physicians March Through August 1991
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
More medical students. The need and available supply
Authors: J. L. Caughey
Journal: JAMA (1966)

It is not easy for the 25th speaker on a program devoted to medical education to add anything which is new or different from what has already been said. But it certainly is appropriate to give some attention to the number and quality of the young people from whom the future members of the medical profession are being created. Obviously, medical schools select their students from the pool of candidates who make themselves known by submitting applications. In this country, to qualify for consideration by a medical school, the candidate must have completed at least two and usually three years of college study. This is an extremely effective screening device, since a student must perform well in his "premedical" program if he is to have much chance for acceptance by a medical school. In effect, this means that access to medicine as a career is very greatly affected by the
Hypoplastic anemia associated with metolazone
Authors: K. Suh
Journal: JAMA (1979)

<h3>To the Editor.—</h3> In the article "The Interface Between Undergraduate and Graduate Medical Education" (241:1148, 1979), William D. Holden, MD, names a problem in medical education but does not define it. For my personal use, I define the interface as the transition from juvenile education to adult education. My insight was stimulated some years ago when, in another context, I heard William Griffith, of the Department of Education of the University of Chicago, make the following statement: "I think that one of our greatest problems in dealing with [teaching] adults is the fact that they have been children." There is a difference between juvenile and adult education; the difference is definable and recognizable, but the details of a medical school curriculum content, elective or required, are not much to the point. The schoolchild, college student, and medical student are fit into the juvenile education system lacking well-defined personal goals and
MEDICAL JOURNALS AND WEEKLY EDITIONS.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
08.21 Dominant b-cell receptor clones in peripheral blood predict onset of arthritis in individuals at risk for rheumatoid arthritis
Authors: Paul-Peter Tak, Marieke E Doorenspleet, Marjolein J.H. de Hair, Paul L Klarenbeek, Marjan H van Beers-Tas, Antoine HC van Kampen, Dirkjan van Schaardenburg, Danielle M Gerlag, Frank Baas, Niek de Vries
Journal: Annals of the Rheumatic Diseases (2017)