Osteopenia
Authors: I. HOLLÓ
Journal: Annals of Internal Medicine (1977)

Letters and Corrections1 November 1977OsteopeniaI. HOLLÓ, M.D., D. MED. SCI., J. SZÜCS, M.D., M. BOROSS, F. SZALAY, M.D.I. HOLLÓ, M.D., D. MED. SCI.Search for more papers by this author, J. SZÜCS, M.D.Search for more papers by this author, M. BOROSSSearch for more papers by this author, F. SZALAY, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-87-5-637_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: We have read with great interest the excellent review of Thomson and Frame, "Involutional Osteopenia: Current Concepts" (Ann Intern Med 85:789-803, 1976). We wish to describe some of our findings and our hypothesis on the pathogenesis of postmenopausal osteoporosis.1. In accord with the findings of Urist and Vincent we have found that urinary excretion of androgen metabolites is lower in patients with postmenopausal osteoporosis than in matched control subjects (1).2. Conjugated dehydroepiandrosterone in the plasma of osteoporotic patients is significantly decreased (2).3. The decreased calcitonin sensitivity in male rats after castration is well known;...References1. HOLLÓFEHÉR IT: Studies on postmenopausal osteoporosis. I. Urinary excretion of 17-ketosteroid fractions in postmenopausal osteoporosis. Acta Med Acad Sci Hung 20:233-235, 1964 MedlineGoogle Scholar2. HOLLÓFEHÉRSZÜCS ITJ: Serum dehydroepiandrosterone, androsterone and cortisol level in primary postmenopausal and other type osteoporosis. Acta Med Acad Sci Hung 27:155-160, 1970 MedlineGoogle Scholar3. HOLLÓBOROSSSZÜCS IMJ: Effect of sex hormone deficiency on calcitonin-induced hypocalcaemia. Akt Geront 8:609-616, 1975 Google Scholar4. HOLLÓSZÜCSSTECZEK IJK: Effect of norandrosterone-decanoate on calcium tolerance curves of patients with primary osteoporosis. Data on the mode of action of anabolic compounds in osteoporosis. Endokrinologie 58:326-330, 1971 MedlineGoogle Scholar5. HOLLÓSZALAYSTECZEKSZÜCS IFKJ: Terheléses serum-calciumgörbe postmenopausàs osteoporosisban. Diagnosztikai eljàràs. Magy Belorv Arch 28:194-198, 1975 Google Scholar1. RIGGSJOWSEYKELLYARNAUD BJPC: Role of hormonal factors in the pathogenesis of postmenopausal osteoporosis. Isr J Med Sci 12:615-619, 1976 MedlineGoogle Scholar2. JUDDJUDDLUCASYEN HGWS: Endocrine function of the postmenopausal ovary: concentrations of androgens and estrogens in ovarian and peripheral vein blood. J Clin Endocrinol Metab 39:1020-1024, 1974 CrossrefMedlineGoogle Scholar3. GORDANVAUGHAN GC: Clinical Management of the Osteoporoses. Acton, Massachusetts, Publishing Sciences Group, Inc., 1976, p. 94 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: First Department of Medicine and Gerontologic Research Group Semmelweis University Medical School 1083 Budapest, Korányi Sándor u 2/A Hungary PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByBifunctional group participated nitrile group hydrolyzing enzyme model systems: Hydrolysis of the nitrile group of α-aminophenylacetonitrile to phenylglycineamide and phenylglycine by various thiol compounds 1 November 1977Volume 87, Issue 5Page: 637-637KeywordsAndrogensBlood plasmaCalcitoninDehydroepiandrosteroneExcretionMetabolitesOsteopeniaOsteoporosisPathogenesis Issue Published: 1 November 1977 PDF DownloadLoading ...