tbuckley/cabot-search huggingface dataset:
Clinical Experience with Iron-Sorbitol, a New Intramuscular Iron Medication
Journal: JAMA (1963)

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Alcohol Dependence and Use of Treatment Services Among Women in the Community
Authors: Li-Tzy Wu, Chris L Ringwalt
Journal: American Journal of Psychiatry (2004)

OBJECTIVE: This study examined the extent and characteristics of alcohol dependence and the perceived need for and use of alcohol treatment services among women compared with men in a nonclinical sample of adults 18–64 years of age. METHOD: Data were drawn from the 1999 National Household Survey on Drug Abuse. The authors calculated rates and correlates of alcohol dependence and treatment among adult alcohol users in this sample. RESULTS: About 3% of the women in the survey met criteria for DSM-IV alcohol dependence in the previous year. About 13% of these women received alcohol treatment services in the same period. Only 8% of the women who did not receive treatment perceived a need for treatment. Younger women—those who were 18–25 years of age—were more likely to be dependent on alcohol but less likely to perceive a need for treatment or to use treatment services. Among alcohol-dependent women who received no treatment, those with a family income of $75,000 or more, those who had two or more children living with them, and those who were not dependent on psychotherapeutic medications were less likely to perceive a need for help. CONCLUSIONS: There were no significant differences between men and women in use of treatment services, location of services received, and perceived need for treatment. However, correlates of treatment service use varied somewhat by gender. These findings suggest that the goal of efforts to reduce barriers to alcohol treatment services should be to change people's attitudes toward alcohol abuse and seeking professional help.
Editorial Board
Authors: Andrew Schachat, Henry Jampel, Ike Ahmed, Douglas Miami, F Tin, Aung Singapore, James Brandt Sacramento, Wiley Chambers, I Washington, Susan Day, San Francisco, William Freeman, La Jolla, David Friedman Baltimore, Mingguang He, Glenn Durham, Ronald Madison, Richard Alan, Lewis Houston, Maureen Maguire, Steven Philadelphia, New Mccormick, Joel York, Arthur Mueller, David Musch, Ann Arbor, Steven Charlottesville, Joan O'brien Philadelphia, Denis O', Day Nashville, Peter Rubin, West Beach, Refractive Matters, Roger Steinert, Richard Stone Philadelphia, Alan Sugar, M Rohit Varma, Thomas Weingeist Iowa, Richard London, Veronica Managing, Lynn Logan, Patricia Previll, Richard Zorab Vp, Ophthalmic Knowledge, Hal Straus, Franco Recchia Nashville, Debra Shetlar
Journal: Ophthalmology (2011)
Principles and Practice of Bacteriology
Journal: JAMA (1941)

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Prognosis of Occult Carcinoma of the Breast
Journal: JAMA (1963)

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An epidemic of resistant Salmonella in a nursery. Animal-to-human spread
Authors: R. W. Lyons
Journal: JAMA (1980)

A<i>Salmonella heidelberg</i>epidemic in a hospital nursery was traced to infected calves on a dairy farm where the mother of the index patient lived. The<i>Salmonella</i>isolates from all cases were resistant to chloramphenicol, sulfamethoxazole, and tetracycline. Verification of the spread of infection from the farm animals to a hospital population is unusual and raises questions about the hazards of antibiotic animal-feed preparations that may induce infection with resistant organisms in humans. (<i>JAMA</i>243:546-547, 1980)
"God and the Doctor we Alike Adore."
Authors: None C. B. W.
Journal: JAMA (1896)

Monongahela, Pa., Nov. 30, 1896. <h3>To the Editor:</h3> —R. M. W. of Brooklyn, N. Y., will find the lines, "God and the doctor we alike adore, But only when in trouble, not before. The trouble o'er, both are alike requited; God is forgotten, and the doctor slighted." in Ben Jonson's "Magnetic Lady," Act II, Scene 1.
A Hand-Book of Surgery. For Students and Practitioners.
Journal: JAMA (1904)

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Lumbosacral skin lesions as markers of occult spinal dysraphism
Authors: D. E. Hall
Journal: JAMA (1981)

Early treatment of occult spinal dysraphism may prevent progressive neurological deficits. However, diagnosis is often delayed until the onset of irreversible neurological damage. A review of data from the literature and patients at Johns Hopkins Hospital suggests that lumbosacral skin abnormalities such as tufts of hair, hemangiomas, lipomas, skin tags, or pigmented nevi should alert the physician to search for occult spinal dysraphism. In the asymptomatic patient with a skin lesion, roentgenography of the lumbosacral spine is a useful screening procedure for identifying treatable underlying problems. (<i>JAMA</i>1981;246:2606-2608)
SECTION ON PHYSIOLOGY AND DIETETICS.
Journal: JAMA (1892)

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Reply:
Authors: Ian N. Hines
Journal: Hepatology (2008)

We thank Drs. Feng and Xu for their interest in our recent article published in HEPATOLOGY. The authors bring up a very interesting point regarding the similarities in impairment of liver regeneration between steatosis and concanavalin A–induced hepatitis. Our laboratory has a strong interest both in the mechanisms of liver regeneration but also in the development and progression of fatty liver disease.1, 2 Although we did not directly observe increases in lipid accumulation by routine histopathological examination, we did not perform a systematic evaluation of this possibility in our study as Drs. Feng and Xu have done. In our recent report, we speculated that disruption in key proproliferative cytokine production (particularly interleukin-6) in conjunction with increased expression or activation of inhibitory factors such as p21 and Smad2 likely contribute to the decreased hepatocellular proliferation observed following partial hepatectomy in concanavalin A–pretreated mice, though we stopped short of defining a direct connection. This point should be clarified, because we do not believe that oval cells reduce hepatocellular proliferation but that decreased mature hepatocyte proliferation stimulates or promotes the expansion of oval cells secondarily within the regenerating liver. The inclusion of lipid accumulation as the intermediary between T cell–mediated hepatitis and inhibition of hepatocellular regeneration is novel and most interesting. There is copious evidence in the literature to suggest a connection between lipid accumulation within hepatocytes and their decreased propensity or ability for proliferation.3 Likewise, there is evidence to suggest that key proinflammatory cytokines including tumor necrosis factor α and others may modulate the development and progression of hepatosteatosis.4-6 The ability of T cells to either directly or indirectly modify lipid accumulation within hepatocytes has not been investigated, though very recent preliminary studies by our laboratory would suggest that T cells themselves may indeed contribute to the progression of hepatosteatosis. Together, the findings by Drs. Feng and Xu and our recent preliminary data provide an important and exciting connection between concanavalin A–induced, T cell–mediated liver injury and hepatocellular lipid accumulation. Future investigation into the direct mechanisms by which this occurs will provide the experimental and clinical community with important information regarding the impact of lymphocyte-mediated liver injury on the initiation or enhancement of secondary pathologies including hepatosteatosis. Ian N. Hines Ph.D.*, * Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, NC.
Walsh's Physicians' Combined Call-Book and Tablet.
Journal: JAMA (1910)

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A statewide early defibrillation initiative including laypersons and outcome reporting
Authors: B. E. Haynes
Journal: JAMA (1991)

Rapid delivery of defibrillatory shocks increases survival in patients with cardiac arrest. The automated external defibrillator interprets cardiac rhythms and delivers electrical shocks, permitting appropriate defibrillation by persons with minimal training. California initiated a program for early defibrillation by basic emergency medical technicians, using manual or automated external defibrillators, and by public safety personnel (fire fighters, peace officers, and public lifeguards), using automated external defibrillators. The program includes a system for reporting outcomes statewide. In the first 46 months under this program, 1487 patients received defibrillatory shocks; 1009 (68%) of these patients had witnessed ventricular fibrillation. Of the latter group, 191 were discharged from the hospital, representing 19% of those with witnessed ventricular fibrillation and 13% of all patients who had had shocks applied. California also implemented a framework of training and medical direction for defibrillation by laypersons using automated external defibrillators. Early defibrillation by basic emergency medical technicians and public safety personnel, encouraged by appropriate regulatory changes, results in gratifying survival rates. (<i>JAMA</i>. 1991;266:545-547)
Psychiatry
Authors: Vernon P. Williams
Journal: New England Journal of Medicine (1949)

IT IS gratifying to psychiatrists to see the importance of their specialty more and more clearly recognized and understood by medicine generally and by the public. The situation beginning with and since the war suggests that psychiatry may be approaching its heyday. The hope should be that its structure is or will be on foundations so sound that as time goes on it will not suffer through periods of questionable repute.Even at present, it may be considered, a little uneasily, if there are signs of excessive enthusiasm or fervor in some directions. In speaking of the ominously revolutionary trends . . .
LE traitement DES MALADES NERVEUX et MENTAUX. Manuel édité sous les auspices de la Société Suisse de Psychiatrie.
Journal: JAMA (1931)

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Health education for hypertensive patients
Authors: D. M. Levine
Journal: JAMA (1979)

Three educational interventions for the control of essential hypertension in ambulatory patients were based on analyses of the educational needs of patients and providers. The educational program increased reported compliance with medication, improved the proportion of patients losing weight, and improved appointment keeping. Most important, there was a favorable effect on blood pressure (BP) control. The proportion of patients with BP under control in the group assigned to all three interventions increased by 28% (from 38% to 66%), while the proportion in the control group receiving standard medical therapy with no educational interventions remained unchanged at 42%. (<i>JAMA</i>241:1700-1703, 1979)
WHAT IS DIPHTHERIA?
Journal: JAMA (1891)

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THE MOVING PHYSICIAN.
Journal: JAMA (2007)

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Health Control in Mercantile Life.
Journal: JAMA (1926)

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