tbuckley/cabot-search huggingface dataset:
THE SYMPTOMATIC VALUE OF CHANGES IN THE NAILS.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medicaid. The role of the states
Authors: T. Riley
Journal: JAMA (1995)

MEDICAID is a federal program, but because it is administered by the states, it is they who are often held directly accountable by providers and beneficiaries for the program's shortcomings, even when those shortcomings are part of federal law. For states, frustration with the federal program rests largely in three areas: (1) eligibility requirements that are cumbersome to administer and restrict coverage only to certain groups among the poor; (2) reimbursement rate protections for hospitals and nursing facilities that result in disproportionate reductions in fees paid to physicians, home care, and other provider groups when budgets must be constrained; and (3) requirements that the program must provide "cookie cutter" services statewide to any and all persons eligible for Medicaid. States point out that from 1987 through 1992, the federal government imposed no fewer than 30 new mandates on them related to program eligibility, reimbursement, and services.<sup>1</sup>Many of those
Informed consent.
Authors: O J Lehmann, D McLeod, C Dowling, R N Carroll
Journal: BMJ (1993)

EDITOR,-D D Kerrigan and colleagues report that giving patients detailed information before hernia repair did not significantly increase their anxiety but say that it would help in subsequent litigation.'Although I accept the philosophy behind their conclusion, elective hernia repair is unlikely to give rise to many cases of litigation.Anxiety may be associated with practically every operation.It is doctors' utmost duty to warn of the most serious and most common complications: the Sidaway case in the English courts is a precedent.2Lord Bridge stated that if a complication occurs in more than 10% of cases the patient must be told.In the case of specific risks, such as death, paralysis, and blindness, the patient must also be told even if the risk is less than 1%.This common law, also quoted by the NHS Management Executive's Guide to Consent for Examination or Treatment,3 is not applicable in Kerrigan and colleagues' study: complications do not occur in more than 10% of patients after elective hernia repair, nor are there specific risks of death, paralysis, or blindness.Thus the choice of this procedure for examining consent is not appropriate.The information sheets given to both groups in the study were inadequate and did not satisfy the Department of Health's guidelines3 as they did not mention possible alternatives to elective hernia repair.Doctors should make their own judgment as to how much information each patient needs.There is no point in loading patients with all possible information available.As long as the doctor has
Return
Authors: Joan Michelson
Journal: JAMA (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
An algorithm for the operational assessment of adverse drug reactions. I. Background, description, and instructions for use
Authors: M. S. Kramer
Journal: JAMA (1979)

Despite widespread clinical and epidemiologic attention to adverse drug reactions (ADRs), their clinical identification has been a nonreproducible act of unspecified subjective judgment; adequate operational criteria have not been available for diagnostic decisions about the cause of an observed untoward clinical manifestation. To improve scientific precision in the diagnosis of ADRs, we have developed an algorithm that provides detailed operational criteria for ranking the probability of causation when ADR is suspected between a drug and a clinical manifestation. The algorithm provides a scoring system for six axes of decision strategy: previous general experience with the drug, alternative etiologic candidates, timing of events, drug levels and evidence of overdose, dechallenge, and rechallenge. The sum of the scores is ordinally partitioned to rate the candidate ADR as definite, probable, possible, or unlikely. (<i>JAMA</i>242:623-632, 1979)
Fildes and "The Doctor"
Authors: G. E. Gifford
Journal: JAMA (1973)

One of the most popular paintings at the turn of the century was "The Doctor." More than a million engravings of it appeared in the United States in parlors and physicians' waiting rooms. Painted by Sir Luke Fildes, RA (Royal Academy), in 1891 for Sir Henry Tate, it still hangs in the museum Sir Henry founded, the Tate Gallery in London. Hailed as a Victorian masterpiece when it was painted, the reactions of the public and the profession, at the time and throughout the years, help us understand the patient's image of the physician and the physician's image of himself. There is little hope in this sad picture. The child is seriously ill, quite near to death. The mother is sobbing in the background, comforted by her husband. The child rests on a roughly made bed of two chairs, and the doctor sits brooding before her. There is no more
Pancreatic Adenocarcinoma
Authors: Margaret Tempero, J Pablo Arnoletti, Edgar Ben-Josef, Pankaj Bhargava, Ephraim S Casper, Paula Kim, Mokenge P Malafa, Eric K Nakakura, Stephen Shibata, Mark Talamonti, Hanlin Wang, Christopher Willett
Journal: Journal of the National Comprehensive Cancer Network (2007)

An estimated 33,370 people will die of pancreatic cancer in the United States in 2007, making it the fourth most common cause of cancer-related death among men in the United States. Although incidence is roughly equal among men and women, African Americans appear to have a higher incidence of pancreatic cancer than white Americans. The NCCN Pancreatic Adenocarcinoma Guidelines discuss risk factors, diagnosis and staging, and treatment through palliative care or surveillance for patients with tumors of the exocrine pancreas. Overall, in view of the poor outcome of patients with all stages of pancreatic cancer, the NCCN panel recommends that investigational options be considered in all phases of disease management. Specific palliative measures are recommended for patients with advanced pancreatic adenocarcinoma characterized by biliary or gastric obstruction, severe abdominal pain, or other tumor-associated manifestations of the disease. For the most recent version of the guidelines, please visit NCCN.org
Tandem Versus Single Autologous Hematopoietic Cell Transplantation for the Treatment of Multiple Myeloma: A Systematic Review and Meta-analysis
Authors: A. Kumar, M. A. Kharfan-Dabaja, A. Glasmacher, B. Djulbegovic
Journal: JNCI Journal of the National Cancer Institute (2009)

BackgroundEvidence bearing on the efficacy of tandem autologous hematopoietic transplant (AHCT) vs a single AHCT in patients with multiple myeloma (MM) is conflicting. We performed a systematic review and meta-analysis to synthesize the existing evidence related to the effectiveness of tandem vs single AHCT in patients with MM.
Eclampsia during the 16th gestational week
Authors: M. D. Lindheimer
Journal: JAMA (1974)

Eclampsia occurred in a previously normotensive nullipara, without evidence of hydatiform disease or Rh isoimmunization, during her 16th gestational week. Unawareness that this entity may occur so early in pregnancy led to diagnostic delay, and convulsions continued. Institution of specific therapy resulted in cessation of convulsions and blood pressure decreased immediately after pregnancy interruption. (<i>JAMA</i>230:1006-1008, 1974)
Leads from the MMWR. Toxic shock syndrome associated with influenza--Minnesota
Journal: JAMA (1986)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 1565: Characterization and Outcome of Patients with Severe Symptomatic Aortic Stenosis Referred for Percutaneous Aortic Valve Replacement
Authors: Samir R Kapadia, Lars Svensson, Sachin Goel, Lee Wallace, Leonardo Rodriguez, William Stewart, E M Tuzcu
Journal: Circulation (2007)

Introduction: Although severe symptomatic aortic stenosis (AS) is associated with poor long-term outcome without aortic valve replacement (AVR), many patients are considered high risk for AVR surgery. These patients are typically not referred to cardiac surgery and therefore remain ill defined. Many of these patients are now referred for possible percutaneous AVR (percAVR). We report the clinical and echocardiographic characteristics of these patients with their outcome. Methods: All patients screened for percAVR between 2/06 to 3/07 were studied. Clinical and echocardiographic characteristics of patients undergoing surgical AVR (sAVR), percAVR, balloon aortic valvuloplasty (BAV) and medical management were compared. Clinical follow-up was performed for all cause mortality. Patients that were bridged to sAVR or percAVR after BAV were included in the respective groups. Results: We screened 92 pts for consideration of percAVR at our institution in 1 year. Of these, 19 pts underwent surgical AVR, 18 patients percAVR and 36 patients had medical management without BAV. BAV was performed in 30 patients of which 8 pts underwent percAVR and 3 had sAVR. Most common reasons for medical management included death while being screened (n=10, 28%), patient not interested in the study (n=10, 28%) and questionable severity of symptoms or AS (n=9, 25%). BAV was used in patients that could not wait for percAVR to become available with an intention to bridge. This could not be accomplished in 9 (45%) pts due to death while waiting for percAVR, 4 (20%) pts doing well after BAV not wanting percAVR, and the remaining 6 (30%) pts with exclusion from the current percAVR protocol (e.g. age, bleeding, infection, etc). Conclusion: Symptomatic patients with severe AS have high mortality if AVR is not feasible in a timely manner. About one fifth of the patients referred for percAVR could undergo sAVR with good outcome. Patients managed medically or with BAV alone have unfavorable outcomes. Characteristics and Outcome of Screened Patients
EXERCISE IN DIABETES
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CLOSING THE BACK DOORS TO MEDICAL LICENSURE
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
283. HIV Protected Autologous Zinc Finger Nuclease Driven CCR5 Modified CD4 T-Cells CCR5 (SB-728-T) Reduce HIV Viral Load in CCR5 Δ32 Heterozygote Subjects During Treatment Interruption (TI): Correlates of Effect, and Effect of Cytoxan Pre-Conditioning Regimen
Journal: Molecular Therapy (2014)
Correlation Between Dopamine D<sub>2</sub> Receptors in the Ventral Striatum and Central Processing of Alcohol Cues and Craving
Authors: Andreas Heinz, Thomas Siessmeier, Jana Wrase, Derik Hermann, Sabine Klein, Sabine M. Grüsser-Sinopoli, Herta Flor, Dieter F. Braus, Hans Georg Buchholz, Gerhard Gründer, Mathias Schreckenberger, Michael N. Smolka, Frank Rösch, Karl Mann, Peter Bartenstein
Journal: American Journal of Psychiatry (2004)

OBJECTIVE: Alcohol and other drugs of abuse stimulate dopamine release in the ventral striatum, which includes the nucleus accumbens, a core region of the brain reward system, and reinforce substance intake. Chronic alcohol intake is associated with down-regulation of central dopamine D2 receptors, and delayed recovery of D2 receptor sensitivity after detoxification is positively correlated with high risk for relapse. Prolonged D2 receptor dysfunction in the ventral striatum may interfere with a dopamine-dependent error detection signal and bias the brain reward system toward excessive attribution of incentive salience to alcohol-associated stimuli. METHOD: Multimodal imaging, with the radioligand [18F]desmethoxyfallypride and positron emission tomography as well as functional magnetic resonance imaging (fMRI), was used to compare 11 detoxified male alcoholics with 13 healthy men. The authors measured the association of D2-like dopamine receptors in the ventral striatum with alcohol craving and central processing of alcohol cues. RESULTS: Activation of the medial prefrontal cortex and striatum by alcohol-associated stimuli, relative to activation by neutral visual stimuli, was greater in the detoxified alcoholics than in the healthy men. The alcoholics displayed less availability of D2-like receptors in the ventral striatum, which was associated with alcohol craving severity and with greater cue-induced activation of the medial prefrontal cortex and anterior cingulate as assessed with fMRI. DISCUSSION: In alcoholics, dopaminergic dysfunction in the ventral striatum may attribute incentive salience to alcohol-associated stimuli, so that alcohol cues elicit craving and excessive activation of neural networks associated with attention and behavior control.
THE GROWTH OF HAIR
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
International Trends in Rates of Hypospadias and Cryptorchidism
Authors: Leonard J. Paulozzi
Journal: Environmental Health Perspectives (1999)

Researchers from seven European nations and the United States have published reports of increasing rates of hypospadias during the 1960s, 1970s, and 1980s. Reports of increasing rates of cryptorchidism have come primarily from England. In recent years, these reports have become one focus of the debate over endocrine disruption. This study examines more recent data from a larger number of countries participating in the International Clearinghouse for Birth Defects Monitoring Systems (ICBDMS) to address the questions of whether such increases are worldwide and continuing and whether there are geographic patterns to any observed increases. The ICBDMS headquarters and individual systems provided the data. Systems were categorized into five groups based on gross domestic product in 1984. Hypospadias increases were most marked in two American systems and in Scandinavia and Japan. The increases leveled off in many systems after 1985. Increases were not seen in less affluent nations. Cryptorchidism rates were available for 10 systems. Clear increases in this anomaly were seen in two U.S. systems and in the South American system, but not elsewhere. Since 1985, rates declined in most systems. Numerous artifacts may contribute to or cause upward trends in hypospadias. Possible "real" causes include demographic changes and endocrine disruption, among others.
Formulary. A List of Drugs and Preparations Selected as Official for Use in Peking Union Medical College Hospital.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
After Bakke
Authors: JOHN E. MILNER
Journal: Annals of Internal Medicine (1978)

ExcerptThe supreme court's decision on 28 June inRegents of the University of California v. Bakke(1) admitted Mr. Bakke to the first-year class at the University of California, Davis, School of Medicine. That is the clearest consequence of the decision. The spokesmen of various factions have rushed to acclaim the decision, to denounce it, or to accept it as a peculiarly democratic compromise. Among the commentators was Dr. John Cooper, President of the Association of the American Medical Colleges (AAMC). His judgment was that "the only problem for the medical schools will be to find an appropriate weight for...