tbuckley/cabot-search huggingface dataset:
Occupational Disease Surveillance: Carpal Tunnel Syndrome
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Drüsen
Authors: David Goldblatt
Journal: Annals of Internal Medicine (2005)

Ad Libitum3 May 2005DrüsenDavid Goldblatt, MDDavid Goldblatt, MDFrom Penn Yan, NY 14527.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-142-9-200505030-00010 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail My maculae—those spotswhere life comes into focus—are not immaculate.Before their senescence startedto parallel mine,they were my infinitesimallink with the infinite,evidential as stones.Their circular reasoningproved the realityof the visibleby the visibility of the real.They awarded their testamursto linearities, intentional andunintentional:a doorframe, say,or from a black skya sunbeamat 6 p.m.David Goldblatt, MDPenn Yan, NY 14527 Author, Article, and Disclosure InformationAffiliations: From Penn Yan, NY 14527.Current Author Address: David Goldblatt, MD, 232 East Lake Road, Penn Yan, NY 14527. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 3 May 2005Volume 142, Issue 9Page: 750KeywordsAgingReasoning ePublished: 3 May 2005 Issue Published: 3 May 2005 Copyright & PermissionsCopyright © 2005 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Aspects of Prostaglandin Function in the Lung
Authors: Aleksander A. Mathé, Per Hedqvist, Kjell Strandberg, Crystal A. Leslie
Journal: New England Journal of Medicine (1977)

The functions of the lung can be divided into those directly involved with respiration and those that, although perhaps having a secondary effect on respiration, are not its primary concern. It has been recognized that these functions are influenced by several classes of substances, including autacoids, catecholamines and steroids. The purpose of this report is to review the effects of one autacoid, the prostaglandins (PG's), on both respiratory and nonrespiratory functions of the lung.PG's, a group of 20-carbon unsaturated fatty acids, were discovered by von Euler1 and Goldblatt2 almost half a century ago. The eight known PG families are . . .
Carcinogenic Activity of Analogues of &lt;italic&gt;p&lt;/italic&gt;-Dimethylaminoazobenzene. IV. Activity of the Quinoline Analogues&lt;xref ref-type="fn" rid="FN1"&gt;2&lt;/xref&gt;
Journal: JNCI Journal of the National Cancer Institute (1961)

Thirteen isomers of the p-dimethylaminophenylazoquinolines and their corresponding N-oxides were investigated for hepatic carcinogenic activity in Sprague-Dawley rats. The dyes were all fed at the 0.03 percent level, and the more active isomers were also examined at the 0.01 percent level. The isomers are listed in order of decreasing activity, with semiquantitative values based on p-dimethylaminoazobenzene as 6: 6- (p- dimethylaminophenylazo)quinoline, 200+ ; 5-(p-dimethylaminophenylazo)quinoline-1-oxide, 200+; 5-(p-dimethylaminophenylazo)quinoline, 150; 6-(p-dimethylaminophenylazo)quinoline-1-oxide, 100; 4-(p-dimethylaminophenylazo)quinoline-1-oxide, 22; 4-(p-dimethylaminophenylazo)quinoline, 15; 3- (p-dimethylaminophenylazo)quinoline-1-oxide, 3-(p-dimethylaminophenylazo)quinoline, 7-(p-dimethylaminophenylazo)quinoline-1-oxide, 7-(p-dimethylaminophenylazo)quinoline, 8-(p-dimethylaminophenylazo)quinoline-1-oxide, 8-(p-dimethylaminophenylazo)quinoline, and 2-(p-dimethylaminophenylazo)quinoline-1-oxide, with all the latter less than 2.
Blacks Still Trail in HIV Care
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Midostaurin + Chemo Ups AML Survival
Journal: Cancer Discovery (2016)

In a phase III clinical trial, previously untreated patients with acute myeloid leukemia and FLT3 mutations received either the FLT3 inhibitor midostaurin or a placebo during chemotherapy. Patients who received midostaurin had a 5-year survival rate of 50.9% compared with 43.9% for the placebo group, as well as remissions that lasted nearly a year longer.
Placental transfer of theophylline
Authors: J. Dasta
Journal: JAMA (1979)

<h3>To the Editor.—</h3> As a practicing pharmacist, I particularly enjoyed reading the COMMENTARY inTHE JOURNAL, "Child-Resistant Containers for the Elderly." As primary dispensers of prescription medications, pharmacists were directly affected by the passage of the Poison Prevention Packaging Act of 1970 and 1972. I agree with the authors that pharmacists should offer their elderly patients the option to have a non-child-resistant container. Elderly patients have related many instances to me describing their dilemma in trying to open their prescription containers and the variety of instruments they have used in the process: pliers, hammer, screwdriver, hand-operated canopener, and feet—one patient claimed that stomping on his bottle worked at freeing its contents. Another patient stated that her 7-year-old granddaughter could open her bottle when she, herself, could not. The stories are numerous, much to the dismay of the elderly involved. As a solution to this problem in our hospital, the pharmacists
Symposia and Surveys
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Antibody response to core, envelope and nonstructural hepatitis C virus antigens: Comparison of immunocompetent and immunosuppressed patients
Authors: A Lok
Journal: Hepatology (1993)

Some immunosuppressed patients with hepatitis C virus infection do not have detectable levels of antibody to hepatitis C virus on second-generation enzyme immunoassay. Antibodies to the envelope and nonstructural region 5 proteins have not been examined. Four groups of patients with hepatitis C virus infection were studied: (a) 20 immunocompetent patients, (b) 15 hemodialysis patients, (c) 17 kidney transplant recipients and (d) 3 acute leukemia patients who underwent bone marrow transplantation. Serum samples were tested for antibody to hepatitis C virus with a second-generation enzyme immunoassay and multiantigen enzyme immunoassays and for hepatitis C virus RNA with a nested polymerase chain reaction assay. All the immunocompetent patients reacted to C25, C22 and C33C; 90% reacted to nonstructural region 5 antigen and 80% reacted to C100-3. Only 55% reacted against yeast-derived e1 and e2 antigens, but all reacted against vaccinia virus-expressed N e1 and e2 antigens, indicating that the envelope epitopes are conformational and glycosylated. Sixty-five percent to 90% of dialysis and kidney transplant patients reacted to C25, C22 and N e1 and e2, but only 12% to 60% reacted to C100-3, C33C and nonstructural region 5 antigen. Diminution or loss of reactivity to hepatitis C virus antigens was observed after kidney and bone marrow transplantation, with C25 and N e1 and e2 less affected. Our data suggest that incorporation of C25 and N e1 and e2 antigens in the assay for antibody to hepatitis C virus would improve the detection of hepatitis C virus infection in immunosuppressed patients. (HEPATOLOGY 1993;18:497–502.)
John Chapman (1822-1894), sponsor of George Eliot
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A CLERGYMAN'S DEFENSE OF ANIMAL EXPERIMENTATION.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
La suture endoscopique en bourse de l’anastomose gastrojéjunale après gastric bypass entraîne une perte de poids et une amélioration des comorbidités métaboliques
Journal: Endoscopy (2018)

Le gastric bypass en Y (GBP) est un traitement chirurgical efficace de l’obésité morbide. Néanmoins, certains malades reprennent du poids à distance (2 à 20 ans après l’intervention). Cette reprise de poids, concernant près de 30 % des malades, est multifactorielle. La dilatation de l’anastomose gastrojéjunale et de la poche gastrique sus jacente est le seul facteur anatomique associé à cette reprise de poids. La réfection chirurgicale de l’anastomose gastrojéjunale est une intervention relativement complexe associée à une morbidité chirurgicale significative pouvant grever le résultat pondéral. Le dispositif de suture endoscopique Overstitch, distribué par Apollo Endosurgery (USA), est approuvé par la Food and Drug Administration. Il possède de nombreuses applications endoscopiques, notamment bariatrique. Depuis 2004, plusieurs études ont montré l’intérêt de l’Overstitch pour la réduction des anastomoses gastrojéjunales après GBP (Fig. 1).
Leads from the MMWR. Severe neutropenia during pentamidine treatment of Pneumocystis carinii pneumonia in patients with AIDS
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Synopsis of the Practice of Medicine for Practitioners and Students.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nicotine patches
Authors: N. L Benowitz
Journal: BMJ (1995)

Geometric mean lead content in house dust and soil samples in Britain in 1982* and estimated proportions of children aged under 6years with raised blood lead concentrations Estimated % of children with blood lead House dust Soil Location (,ug/g) (,ug/g) >10 I g/dl >25 jig/dI Mean value in national surveyt
Fifth Annual Symposium on Advances In Cancer Treatment Research
Journal: JNCI Journal of the National Cancer Institute (1980)

Journal Article Fifth Annual Symposium on Advances In Cancer Treatment Research Get access JNCI: Journal of the National Cancer Institute, Volume 64, Issue 1, January 1980, Page 207, https://doi.org/10.1093/jnci/64.1.207-a Published: 01 January 1980
Cholestasis and cholangitis.
Journal: BMJ (1968)

As early as 1939 S. Z. Levine and his co-workers'4 showed that premature infants fed on a high-protein diet excreted p-hydroxyphenylpyruvic acid and p-hydroxyphenylactic acid in their urine.It is now well known that raised levels of tyrosine in the serum, together with tyrosyluria, occur frequently in newborn infants, especially if they are premature (neonatal tyrosinaemia, hypertyrosinaemia of premature infants).In a study'5 of 15,000 infants severe tyrosinaemia was detected in 30% of the premature and mild tyrosinaemia in 10% of the full-term infants.This type of tyrosinaemia is more likely to arise when the infant's intake of protein is high; and it usually responds dramatically to a reduction in protein or the addition of ascorbic acid to the diet.In any case it usually clears spontaneously a week or so after birth.It is known that p-H.P.P.A. oxidase is only minimally active in foetal liver, the activity increasing fivefold at term and
Progress in behavior therapy.
Journal: BMJ (1972)

patients who develop influenza, or are exposed to it, necessarily be vaccinated.Though the influenza vaccine used in Britain contains killed influenza virus it may also contain active or latent members of the avian-leucosis group of viruses.Doctors would do well to bear in mind that the protection from available vaccines is far from complete, and that any reduction in the risk of subsequent leukaemia would be very small.The local and other reactions of vaccination in fact probably outweigh the benefits.At the same time it seems reasonable to add influenza to rubella as an illness which should wherever possible be kept away from pregnant women.
Arteritis, myocardial infarction, and rheumatoid arthritis
Authors: I. Karten
Journal: JAMA (1969)

During a four-year period, diffuse vasculitis developed in six of 102 patients with rheumatoid arthritis. Two of these six patients also sustained myocardial infarctions. Coronary arteritis was found at autopsy in one patient; it was also suspected as the cause of the infarction in the patient who survived. The autopsy protocols of an additional 95 rheumatoid patients were examined. For seven patients with myocardial infarctions, no examples of coronary arteritis were found in the available histological sections. The present study does not support the hypothesis that coronary arteritis is a common cause of myocardial infarction in rheumatoid arthritics. However, occasionally, in the presence of widespread vasculitis, coronary arteritis may lead to myocardial infarction.
EXAGGERATION IN REPORTING MEDICAL ADVANCES
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Role of DNA Repair Inhibition in Lead- and Cadmium-Induced Genotoxicity: A Review
Authors: Andrea Hartwig
Journal: Environmental Health Perspectives (1994)

Compounds of lead and cadmium have been shown to be carcinogenic to humans and experimental animals.However, the underlying mechanisms are still not understood.In mammalian cells in culture, lead(lIl) is weakly mutagenic after long incubation times and generates DNA strand breaks only after treatment with high, toxic doses.Cadmium(ll) induces DNA strand breaks and chromosomal aberrations, but its mutagenic potential is rather weak.However, both metals exert pronounced indirect genotoxic effects.Lead(ll) is comutagenic towards UV and N-methyl-N-nitro-Nnitrosoguanidine (MNNG) and enhances the number of UV-induced sister chromatid exchanges in V79 Chinese hamster cells.With regard to DNA repair, lead(ll) causes an accumulation of DNA strand breaks after UV-irradiation in HeLa cells, indicating an interference with the polymerization or ligation step in excision repair.Cadmium(ll) enhances the mutagenicity of UV light in V79 Chinese hamster cells and an increased sensitivity toward UV light is observed in various rodent and human cell lines.Furthermore, an inhibition of unscheduled DNA synthesis after UV-irradiation and a par- tial inhibition of the removal of UV-induced DNA lesions has been shown.For both metals, the indirect genotoxic effects are observed at low, non- toxic concentrations, suggesting that an interference with DNA repair processes may be predominant at biologically relevant concentrations.This might also explain the conflicting results of epidemiological studies obtained for both metals.Possible mechanisms of repair inhibiton are discussed.