tbuckley/cabot-search huggingface dataset:
Abstract O.65: Long-term Outcome of Patients with Giant Coronary Aneurysms caused by Kawasaki Disease: A 30-year Experience in a Single Center in Taiwan
Authors: Wan-Ling Chih, Ming-Tai Lin, Ching-Hao Chang, Chun-An Chen, Shuenn-Nan Chiu, Chun-Wei Lu, Jou-Kou Wang, Mei-Hwan Wu
Journal: Circulation (2015)

Background: Patients with coronary artery aneurysms are at risk for thrombotic and stenotic complications later in their lives. The longitudinal changes of giant coronary aneurysms caused by Kawasaki disease (KD) and their long-term outcome are still unclear in Taiwan. Methods: By retrospective chart review of patients diagnosed with Kawasaki disease complicated by giant coronary aneurysms, we analyze incidence of ischemic event, survival rates, and related risk factors. Results: Between 1984 and 2012, 28 patients (24 male and 4 female) developed giant aneurysms. The mean age at onset and observe period was 3.8 years (range from 0.41 - 10.3 years) and 12 years (0 to 36.8 years), respectively. The initial median coronary Z-score was +5.75 (+0.62 to +19.06) in left main coronary artery, +4.49 (-0.18 to +11.19) in left anterior descending artery, +6.71 (+1.79 to +14.46) in right coronary artery. None of the giant aneurysms regressed during follow-up. The 5- and 35-year survival rates were 0.92 and 0.69, respectively. Except the three deaths, four additional male patients were diagnosed with acute myocardial infarction (AMI), and 2 of these diagnoses occurred within 1 year of KD onset. The incidence of AMI or death in patients with giant aneurysms was 26%, and 67% of the AMI occurred within the first year of KD onset. Clinical evidence of ischemia as documented in nuclear medicine studies was also noted in a further 9 patients (33%), and only one was female. AMI/death-free survival rates were 76% and 69% at 10 and 20 years after KD onset, respectively. Ischemia event-free survival rates were 63% and 36% at 10 and 20 years after disease onset. Men tended to have AMI and ischemia, and only one ischemia patient was female. The hazard ratio of gender on the ischemia events was 2.70 (95% CI: 0.33 - 21.73, P = 0.38). Conclusions: The long-term survival of KD patients with giant coronary aneurysms is guarded. Ischemic heart disease is the major cause of morbidity and mortality. Male KD patients, once they had giant aneurysms, tend to have ischemic events. Other risk factors need to be validated in a larger cohort.
Obstetrics for Nurses.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Thoroughly Modern Medicine
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE JOURNAL, THE GENERAL PRACTITIONER AND MEDICAL PROGRESS.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Extreme pyrexia
Authors: H. B. Simon
Journal: JAMA (1976)

Twenty-eight cases of extreme pyrexia seen in a five-year period were analyzed retrospectively. All of the patients had temperatures between 41.1 C (106 F) and 42.2 C (108 F) with a mean maximum temperature of 41.4 C (106.6 F). Infection, thermoregulatory defects, or a combination thereof accounted for fever in these patients. There was little evidence of direct tissue damage caused by fever, and standard therapy with aspirin or acetaminophen, vigorous surface cooling, and volume expansion was generally successful. Mortality could be related to the extreme pyrexia in only 7% (2) but an additional 21% (6) of these patients later died from serious underlying diseases. (<i>JAMA</i>236:2419-2421, 1976)
Letter: Behavior therapy in anorexia nervosa
Authors: Joseph Wolpe
Journal: JAMA (1975)

<h3>To the Editor.—</h3> There is much substance in the criticisms made by Hilde Bruch; but her inferences about behavior therapy in general are incorrect. It is undeniable that the behavior therapy procedures in the cases she describes produced unsatisfactory results because they were inadequate to the patients' problems. Any system of treatment, of course, has its failures; but one should not condemn a system if it fails when it is used improperly, as it was in these cases. Behavior therapy is defined as the application of experimentally established principles of learning to overcoming unadaptive learned habits. (The expression "behavior modification" that Dr. Bruch employs has often been used as a synonym for behavior therapy, but its range of application actually goes far beyond the clinical context.) As the definition might suggest, behavior therapy is relevant in any psychiatric case whose unadaptive behavior has been acquired by learning. This means, in
John Dalton: Experimental Physiologist and Would-Be Physician.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction: One year's treatment with propranolol after myocardial infarction: preliminary report of Norwegian multicentre trial
Authors: Joseph Whitehead, Yolanda Duralde, Robert Byers, Charles Stevens, Waldo Powell
Journal: BMJ (1982)

age at successive deliveries and at last delivery (positively correlated); height and stature (weight:height) at biopsy (younger women were taller and slimmer); and concentrations of oestrogen and progesterone receptors in the tumour.4Possibly less direct indicators of age were also positively related: the number of children, how long she had nursed them, whether she had a sister with breast cancer, and the time between discovery of disease and biopsy.To separate analytically the effects of aging from other causes that alter the age at diagnosis of breast cancer, data are needed on age- matched women of similar origins who do not have cancer.We thank Dr Robert L Egan for access to his data files, which permitted independent verification of parts of our data.
Therapeutic window for ribavirin therapy in transplant recipients with chronic hepatitis E virus infection
Authors: Midas Mulder, Robert De Man, Nassim Kamar, Gülcan Durmaz, Joep de Bruijne, Thomas Vanwolleghem, Annemiek Van der Eijk, Teun Van Gelder, Dennis Hesselink, Brenda De Winter
Journal: Journal of Hepatology (2020)
Hereditary Gynecologic and Breast Cancer
Journal: JNCI Journal of the National Cancer Institute (1985)

Journal Article Hereditary Gynecologic and Breast Cancer Get access JNCI: Journal of the National Cancer Institute, Volume 74, Issue 2, February 1985, Page 542, https://doi.org/10.1093/jnci/74.2.542-c Published: 01 February 1985
Lack of Association Between Autism and &lt;char aid="99791354" id="ital"&gt;SLC25A12&lt;/char&gt;
Authors: Raquel Rabionet
Journal: American Journal of Psychiatry (2006)

Objective: Autism has a strong, complex genetic component, most likely involving several genes. Multiple genomic screens have shown evidence suggesting linkage to chromosome 2q31–q33, which includes the SLC25A12 gene. Recently, an association between autism risk and two single nucleotide polymorphisms (SNPs) in SLC25A12 was reported. This study aimed to test for association in SLC25A12 in an independent data set of 327 families with autistic offspring. Method: The authors analyzed two SNPs that were significant in the previous study group, as well as seven additional SNPs within the gene. Association analyses for individual SNPs as well as haplotypes were performed. Results: There was no evidence of an association between SLC25A12 and autism. Conclusions: These results suggest that SLC25A12 is not a major contributor to autism risk in these families.
Mistaken Identity
Authors: W. Charles O'Neill
Journal: New England Journal of Medicine (1998)

Effects of Diet and Exercise on Cholesterol LevelsTo the Editor: Stefanick et al. (July 2 issue) were unable to demonstrate a reduction in low-density lipoprotein (LDL) cholesterol levels with diet alone. 1 We believe, however, that dietary intervention alone may be effective in lowering LDL cholesterol levels.The study by Stefanick et al. was well executed, and we commend the authors on their overall design.However, there are three methodologic issues that may have influenced their negative result.First, the adherence of the study population to dietary recommendations was measured by means of two sets of five 24-hour dietary-recall questionnaires, the results of which were averaged, one at base line and the second at one year.Day-to-day diet is influenced by many factors, (e.g., daily hassles, special events, holidays, and so on). 2 Two assessments one year apart are inadequate for determining these patients' adherence to the diet.We recognize that long-term adherence to lifestyle-modification programs is generally disappointing; in fact, 43 percent of patients do not follow long-term regimens, even for the treatment of life-threatening diseases, and 75 percent are unwilling to make lifestyle changes. 3Information regarding patients' adherence to the diet throughout the trial period would provide additional support for the authors' conclusions.Second, the diet used in this study was the National Cholesterol Education Program (NCEP) Step 2 diet. 4ther dietary programs, lower in saturated fat and animal products, have produced greater changes in serum choles-terol levels and regression of coronary heart disease. 5It is important to draw a distinction between the failure of the NCEP Step 2 diet to lower cholesterol and the failure of dietary intervention alone to do so when one is advising patients with dyslipoproteinemias.Third, the study had a two-by-two factorial design, with diet and exercise as the two factors.The only comparisons made were between pairs of the four separate treatment groups.To estimate the "main effect" of diet, one could compare both groups that followed the diet with the two groups that did not.The average reduction in LDL cholesterol in the diet groups was 10.8 mg per deciliter, as compared with 4.0 mg per deciliter in the non-diet groups (the standard error for this difference was 2.9 mg per deciliter).This main effect of diet was nominally significant (P=0.019).The authors' conclusion that exercise is helpful is accurate, but they unduly discount the role of diet.
Descriptive and Longitudinal Observations on the Relationship of Borderline Personality Disorder and Bipolar Disorder
Authors: John G. Gunderson, Igor Weinberg, Maria T. Daversa, Karsten D. Kueppenbender, Mary C. Zanarini, M. Tracie Shea, Andrew E. Skodol, Charles A. Sanislow, Shirley Yen, Leslie C. Morey, Carlos M. Grilo, Thomas H. McGlashan, Robert L. Stout, Ingrid Dyck
Journal: American Journal of Psychiatry (2006)

Objective: The purpose of this study was to test whether borderline personality disorder is a variant of bipolar disorder by examining the rates of co-occurrence in both disorders, the effects of co-occurrence on a longitudinal course, and whether the presence of either disorder confers the risk for new onsets of the other. Method: A prospective repeated-measures design with reliable independent diagnostic measures and 4 years of follow-up was used to assess 196 patients with borderline personality disorder and 433 patients with other personality disorders. Results: Patients with borderline personality disorder had a significantly higher co-occurrence of bipolar disorder (19.4%) than did patients with other personality disorders. However, this co-occurrence did not appear to affect the subsequent course of borderline personality disorder. Although only 8.2% of the borderline personality disorder patients developed new onsets of bipolar disorder, this rate was higher than in patients with other personality disorders. Patients with other personality disorders with co-occurring bipolar disorder generally had more new onsets of borderline personality disorder (25%) than did patients with other personality disorders without co-occurring bipolar disorder (10%). Conclusions: A modest association between borderline personality disorder and bipolar disorder is reported.
Histological Changes Following Regional Chemotherapy
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Körper und Arbeit:
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Angiotensin II type 1 receptor A1166C polymorphism in relation to incident cardiovascular events, hypertension, and blood pressure control in elderly Caucasians and African Americans
Authors: Lucia A. Hindorff, Susan R. Heckbert, Russ Tracy, Zhonghua Tang, Bruce M. Psaty, Richard A. Kronmal, David S. Siscovick, Valle Nazar-Stewart
Journal: Circulation (2001)

P17 Objective: The C allele of the angiotensin II type 1 receptor (AT1R) A1166C polymorphism has been associated in several studies with increased risks of hypertension (HTN) and myocardial infarction (MI), and with enhanced blood pressure (BP) response to ACE inhibitors but not calcium antagonists. Most of these studies were small, and none included large numbers of African Americans. We examined these associations in the Cardiovascular Health Study, an observational cohort study of risk factors for coronary disease and stroke in men and women ≥ 65 years of age. Methods: All 771 self-identified African Americans plus 1333 randomly-selected Caucasians were genotyped for the AT1R polymorphism. BP, medication use, and HTN were assessed annually. Incident MI/coronary death (CHD, n = 125 in whites; n = 60 in blacks), incident total cardiovascular events (CVD, n = 226 in whites; n = 101 in blacks), incident congestive heart failure (CHF, n = 146 in whites; n = 55 in blacks), and incident HTN (n = 184 in whites; n = 85 in blacks) were identified during up to 8 years of follow-up. Results: Genotype frequency distributions differed between whites (AA 49%, AC 41%, CC 10%) and blacks (85%, 15%, 1%, p &lt; 0.0005). Age, gender or HTN at baseline did not differ by genotype in either group. In both whites and blacks, genotype was not associated with incident CHD (HR for AC/CC vs. AA, 95% CI in whites = 1.0, 0.7-1.5; blacks, HR = 0.7, 0.3-1.5), incident total CVD events (whites, HR = 1.0, 0.8-1.3; blacks, HR = 0.9, 0.5-1.6), incident CHF (whites, HR = 1.1, 0.8-1.5; blacks, 0.6, 0.3-1.4) or newly-identified HTN (whites, HR = 0.8, 0.6-1.1; blacks, HR = 1.1, 0.6-1.9). Among treated hypertensives, the association of genotype with controlled BP (&lt;140/&lt;90) did not differ between users of calcium channel blockers and users of ACE inhibitors in either race. Conclusion: In this large population-based elderly cohort, the AT1R A1166C polymorphism was not associated with prevalent or newly-identified HTN, incident CVD events, or BP response to antihypertensive agents in either Caucasians or African Americans.
Are Asylum Physicians Party Pensioners?
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Menstrual Disorders
Authors: Joseph Rogers
Journal: New England Journal of Medicine (1964)

Dysfunctional Uterine Bleeding (Metropathia Hemorrhagia)Dysfunctional bleeding refers to abnormalities of vaginal bleeding in which ovulation does not occur and in which pelvic, or systemic disorders are not evident. The disorder occurs most frequently at the menarche when ovulation has not yet been established and before the menopause when regular ovulation may become less frequent. It can occur, however, at any time of reproductive life. Concepts of the mechanism of the bleeding are not entirely clear. It has been widely held that the irregular acyclic bleeding is due to a normal or a decreased amount of estrogen acting for too . . .