tbuckley/cabot-search huggingface dataset:
60th Annual Congress on Medical Education
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Immunoparesis Recovery As Predictor Marker of Progression after Autologous Stem Cell Transplantation in Multiple Myeloma
Authors: Veronica Gonzalez De La Calle, Eduardo Sobejano, Julio Davila, Enrique M Ocio, Noemi Puig, Norma C Gutierrez, Ramon Garcia-Sanz, Alfonso Garcia de Coca, Jose Mariano Hernandez, Roberto Hernandez, Abelardo Bárez, Jose M. Alonso, Carmen Aguilera, Fernando Escalante, Guillermo Martin, Rosa Lopez, Pilar De la Fuente, Jorge Labrador, Carlos Aguilar, Maria-Victoria Mateos
Journal: Blood (2015)
Hospitalization for congestive heart failure. Explaining racial differences
Authors: M. Alexander
Journal: JAMA (1995)

<h3>Objective.</h3> —To determine whether the higher rate of hospitalization among African Americans for congestive heart failure (CHF) could be explained by racial differences in the prevalence of clinical risk factors for CHF. <h3>Design.</h3> —Retrospective cohort study. <h3>Setting.</h3> —A large health maintenance organization (HMO). <h3>Patients.</h3> —A sample of 64877 enrollees (27% African American and 73% white) of the Northern California Kaiser Permanente Medical Care Program who took at least one multiphasic health checkup (MHC) at or after the age of 40 years and were free of CHF at that time. <h3>Main Outcome Measures.</h3> —First hospitalization with a principal diagnosis of CHF. <h3>Results.</h3> —Among cohort members younger than 60 years at baseline MHC, the age-adjusted risk ratio (RR) (African American/white) for CHF hospitalization was 2.14 for men and 2.73 for women, while for persons 60 years of age and older at MHC, the age-adjusted RR was 1.48 for both sexes. Cox proportional hazards models were used to adjust for risk factors and length of follow-up. In persons aged 60 years and older, the race difference was explained by greater prevalence of hypertension and diabetes in African Americans (RR=1.12; 95% confidence interval [Cl], 0.94 to 1.34 after adjustment for hypertension and diabetes). In those younger than 60 years, findings differed by sex. For men, African-American race was no longer a significant predictor of CHF after adjusting for hypertension, diabetes, left ventricular hypertrophy on electrocardiogram, and body mass index (adjusted RR=1.16; 95% Cl, 0.86 to 1.56). However, among younger women, African Americans continued at increased risk despite adjustment for these variables as well as smoking, plasma cholesterol, renal function, alcohol use, and myocardial infarction (adjusted RR=1.49; 95% Cl, 1.00 to 2.21). <h3>Conclusions.</h3> —In this HMO population, the race differences in first hospitalization for CHF are largely explained by known clinical and behavioral risk factors, although in younger women these risk factors do not completely explain the excess risk among African Americans. These findings highlight the role of hypertension and diabetes in the development of CHF, particularly among African Americans. (<i>JAMA</i>. 1995;274:1037-1042)
Editorial: Hard put for a silver lining
Authors: S. Vaisrub
Journal: JAMA (1975)

Tobacco is an enemy whose crimes are admitted even by its devotees. Its only defense is the claim that the alternatives to smoking—depression, excessive appetite, and nervous tension—may outweigh its dangers. There are, however, circumstances under which smoking may be beneficial. In a study of risk factors for deep vein thrombosis complicating myocardial infarction, Handley and Teather<sup>1</sup>found, to their surprise, that this complication occurred more often in nonsmokers than in cigarette smokers. Deep vein thrombosis was diagnosed by<sup>125</sup>I-labelled fibrinogen scanning in 17 (28%) of the 61 cigarette-smoking patients seen in the coronary care unit of Queen Mary's Hospital, Roehampton, England, as compared with 19 (51%) of their 37 nonsmoking counterparts. The difference became even more significant after high-risk cases, ie, patients aged 70 years or more and those with varicose veins or a history of previous thromboembolism, had been excluded. In the narrowed sample, 9 (41%)
Observations on Plague.The Plague Pandemic.
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical Department, United States Army; Organization and Administration in World War II.
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
BEHAVIOR CHANGES IN CHILDREN SUBJECTED TO TONSILLECTOMY
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
P3.01-28 The Clinical Impact of Comprehensive cfDNA Genomic Testing in Lung Cancer
Authors: S. Geva, A. Belilovski Rozenblum, T. Twito, R. Grinberg, A. Dvir, L. Soussan Gutman, L. Roisman, M. Ilouze, E. Dudnik, A. Zer, O. Rotem, R. Lanman, N. Peled
Journal: Journal of Thoracic Oncology (2018)
Hungry irony
Authors: Nancy C. Andrews
Journal: Journal of Clinical Investigation (2015)

Iron-deficient individuals experience a loss of appetite that can be restored with iron supplementation. It has been proposed that iron influences the satiety hormone leptin; however, a direct link between iron and leptin has remained elusive. In this issue of the JCI, Gao and colleagues demonstrate an inverse relationship between adipocyte iron and leptin that is mediated by iron-dependent activation of cAMP-responsive element binding protein (CREB), the transcription factor that represses leptin transcription. Together, the results of this study provide a mechanistic connection between dietary iron and the appetite-regulating hormone leptin.
Dual role of α-defensin-1 in anti–HIV-1 innate immunity
Authors: Theresa L. Chang, Jesus Vargas, Armando DelPortillo, Mary E. Klotman
Journal: Journal of Clinical Investigation (2005)

α-Defensins are abundant antimicrobial peptides in polymorphonuclear leukocytes and play an important role in innate immunity. We have previously shown that α-defensin-1 can inhibit HIV-1 replication following viral entry. Here we examined the molecular mechanism(s) of α-defensin-1–mediated HIV-1 inhibition. α-Defensin-1 had a direct effect on HIV-1 virions at a low MOI in the absence of serum. The direct effect on HIV-1 virions was abolished by the presence of serum or an increase in virus particles. Studying the kinetics of the HIV life cycle revealed that α-defensin-1 inhibited steps following reverse transcription and integration. Analysis of PKC phosphorylation in primary CD4+ T cells in response to α-defensin-1 indicated that α-defensin-1 inhibited PKC activity. Pretreatment of infected CD4+ T cells with a PKC activator, bryostatin 1, partially reversed α-defensin-1–mediated HIV inhibition. Like α-defensin-1, the PKC isoform–selective inhibitor Go6976 blocked HIV-1 infection in a dose-dependent manner. Furthermore, kinetic studies and analysis of HIV-1 products indicated that α-defensin-1 and Go6976 blocked HIV-1 infection at similar stages in its life cycle, including nuclear import and transcription. Taken together, our studies demonstrate that, in the absence of serum, α-defensin-1 may act directly on the virus, but, in the presence of serum, its effects are on the cell, where it inhibits HIV-1 replication. At least 1 of the cellular effects associated with HIV inhibition is interference with PKC signaling in primary CD4+ T cells. Studying the complex function of α-defensin-1 in innate immunity against HIV has implications for prevention as well as therapeutics.
Error in Figure 3
Authors: William Silverstein, Yulia Lin, Matthew Cheung
Journal: JAMA Internal Medicine (2019)

Pranita D. Tamma, MD, MHS; Anna T. Conley, BA; Sara E. Cosgrove, MD, MS; Anthony D. Harris, MD, MPH; Ebbing Lautenbach, MD, MPH, MSCE; Joe Amoah, MD; Edina Avdic, PharmD, MBA; Pam Tolomeo, MPH; Jacqueleen Wise, BA; Sonia Subudhi, BA; Jennifer H. Han, MD, MSCE; for the Antibacterial Resistance Leadership Group
THE MEDICAL DEPARTMENT OF THE NATIONAL GUARD AND OF THE ARMY.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nutrition
Authors: C. Wayne Callaway
Journal: JAMA (1984)

In 1980, the US Department of Agriculture and the Department of Health, Education, and Welfare jointly published the "Dietary Guidelines for Americans," which stated: eat a variety of foods, maintain ideal weight, avoid too much fat, saturated fat, and cholesterol, eat foods with adequate starch and fiber, avoid too much sugar, avoid too much sodium, and if you drink alcohol, do so in moderation. Subsequent reports of research,<sup>1,2</sup>symposia,<sup>3</sup>and expert panels<sup>4,5</sup>have tended to support the overall message of the guidelines. The most controversial guideline was to avoid fat and cholesterol. There was general agreement that elevated serum cholesterol concentrations (in particular, low-density lipoprotein-bound cholesterol) were associated with increased risks for premature coronary artery disease, but it had not been demonstrated adequately whether interventions designed to lower serum cholesterol levels could improve outcome. Several reports have now shown this to be the case—both in reducing myocardial
Training in accident and emergency.
Journal: BMJ (1990)

stung region.In the case of stone fish poisoning, however, it is best that the concentrated necrotising venom is allowed to diffuse freely away from the region.Deaths due to the svstemic effects of the venom are extremely rare, with onlv a couple recorded in published work.Infection often occurs with this type of injury.It should be remembered that marine bacteria comprise a wide range of organisms, and many are resistant to common antibiotics and also may require saline media for culture.It follows that debridement should be assisted by washing the wound well with fresh or preferably sterile water.The drug of first choice is trimethoprim-sulpha- methazole.Tetanus prophvlaxis should also receive attention.
Use and Abuse of Cotton Buds
Authors: Jonathan C Hobson, Jeremy A Lavy
Journal: Journal of the Royal Society of Medicine (2005)

Ear injuries caused by cotton buds are commonly seen in ear, nose and throat (ENT) practice. We asked 1000 patients attending an ENT referral clinic whether they used cotton buds to clean the ear canal. Of the 325 who responded, 171 said they did. The frequency of use was no higher in those with ear complaints than in those with nose and other complaints. 15-20% of respondents disagreed with the statements that cotton buds can cause infections, wax impaction or perforations. On the evidence of this survey, manufacturers' warnings need to be fortified.
Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells
Authors: Hilary J. McKenna, Kim L. Stocking, Robert E. Miller, Kenneth Brasel, Thibaut De Smedt, Eugene Maraskovsky, Charles R. Maliszewski, David H. Lynch, Jeffrey Smith, Bali Pulendran, Eileen R. Roux, Mark Teepe, Stewart D. Lyman, Jacques J. Peschon
Journal: Blood (2000)
Reply
Authors: Tammy Kuang, Chunwei Zhang, Linda M. Zangwill, Robert N. Weinreb, Felipe A. Medeiros
Journal: Ophthalmology (2016)

We thank Professor Sommer for his interest in our article. We certainly recognize his pioneering work in demonstrating the importance of retinal nerve fiber layer assessment in detecting early glaucomatous damage. Professor Sommer's work has certainly inspired the development of technologies for better assessment of the retinal nerve fiber layer in the decades that followed his publications. We have previously cited his work in many of our publications, including a recent comprehensive review.1Medeiros F.A. Evaluating the optic nerve for glaucomatous progression.in: Schacknow P.N. Samples J.R. Glaucoma book: a practical, evidence-based approach to patient care. Springer, New York2010: 203-207Crossref Scopus (1) Google Scholar, 2Medeiros F.A. Zangwill L.M. Bowd C. et al.Comparison of scanning laser polarimetry using variable corneal compensation and retinal nerve fiber layer photography for detection of glaucoma.Arch Ophthalmol. 2004; 122: 698-704Crossref PubMed Scopus (57) Google Scholar, 3Tatham A.J. Miki A. Weinreb R.N. et al.Defects of the lamina cribrosa in eyes with localized retinal nerve fiber layer loss.Ophthalmology. 2014; 121: 110-118Abstract Full Text Full Text PDF PubMed Scopus (78) Google Scholar, 4Tatham A.J. Weinreb R.N. Zangwill L.M. et al.Estimated retinal ganglion cell counts in glaucomatous eyes with localized retinal nerve fiber layer defects.Am J Ophthalmol. 2013; 156: 578-587Abstract Full Text Full Text PDF PubMed Scopus (30) Google Scholar However, owing to space limitations and the recent insistence by journals to limit the number of cited references, we did not cite this important reference. Given the fact that assessment of the retinal nerve fiber layer by photographs is currently rarely used in clinical practice, we have refrained from comparing our results to those of Sommer et al.5Sommer A. Miller N.R. Pollack I. et al.The nerve fiber layer in the diagnosis of glaucoma.Arch Ophthalmol. 1977; 95: 2149-2156Crossref PubMed Scopus (369) Google Scholar Re: Kuang et al.: Estimating lead time gained by optical coherence tomography in detecting glaucoma before development of visual field defects (Ophthalmology 2015;122:2002-9)OphthalmologyVol. 123Issue 6PreviewAlthough digital platforms make it extraordinarily easy to search the world's literature, I have noted a disconcerting laziness on the part of modern authors when it comes to searching out published data on subjects on which they are working. The most recent case in point is the interesting article by Kuang et al in the October 2015 issue of Ophthalmology.1 They followed 75 patients suspected of having glaucoma with periodic optical coherence tomography until the time they first developed confirmed visual field defects on automated perimetry and were able to demonstrate that 35% had abnormal retinal nerve fiber layer thickness measurements 4 years previously. Full-Text PDF
THE CHANGES IN NERVE CELLS DUE TO FUNCTIONAL ACTIVITY.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
National Symposium on Head and Neck Cancer
Journal: JNCI Journal of the National Cancer Institute (1977)

Journal Article National Symposium on Head and Neck Cancer Get access JNCI: Journal of the National Cancer Institute, Volume 58, Issue 5, May 1977, Page 1543, https://doi.org/10.1093/jnci/58.5.1543-d Published: 01 May 1977
Nonhuman primate-associated viral hepatitis type A. Serologic evidence of hepatitis A virus infection
Authors: J. L. Dienstag
Journal: JAMA (1976)

Since 1961, viral hepatitis has been recognized as an occupational hazard among handlers of newly imported chimpanzees and other nonhuman primates. To determine whether previously reported cases were caused by human viral hepatitis type A, we tested paired serum samples from two outbreaks for antibody to hepatitis A antigen (anti-HA) by immune adherence hemagglutination (IAHA), a recently available test. In both outbreaks, one of hepatitis transmitted from chimpanzee to man (Michigan, 1964), the second from chimpanzee to chimpanzee, man, and woolly monkey (Connecticut, 1971), serologic data documented recent hepatitis A virus infection among contacts—human and nonhuman primate—of implicated chimpanzees. This confirms serologically a previously noted epidemiologic association between nonhuman primate-associated hepatitis and human viral hepatitis, type A. (<i>JAMA</i>236:462-464, 1976)
Persistence of Treponema pallidum following penicillin G therapy. Report of two cases
Authors: E. C. Tramont
Journal: JAMA (1976)

The isolation of<i>Treponema pallidum</i>from cerebrospinal fluid (CSF) obtained from two adult patients, both of whom had normal CSF values except for positive fluorescent treponemal antibody-absorption (FTA-ABS) tests and both of whom had received currently recommended courses of penicillin, raises important considerations in the treatment of neurosyphilis in adults. (<i>JAMA</i>236:2206-2207, 1976)