tbuckley/cabot-search huggingface dataset:
Prophylactic Penicillin and Postoperative Chest Infections
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum to: comparison of the three-dimensional organization of sperm and fibroblast genomes using the Hi-C approach
Authors: Nariman Battulin, Veniamin S. Fishman, Alexander M. Mazur, Mikhail Pomaznoy, Anna A. Khabarova, Dmitry A. Afonnikov, Egor B. Prokhortchouk, Oleg L. Serov
Journal: Genome biology (2016)
Solitary extramedullary plasmacytoma in the retroperitoneum
Authors: Tse‐Ching Chen, Jin‐Hou Wu, Kwai‐Fong Ng, Jau‐Min Lien, Chien‐Fu Hung
Journal: American Journal of Hematology (1998)

Solitary extramedullary plasmacytoma is an uncommon neoplasm and occurs most frequently in the upper respiratory tract. Herein, we reported a solitary extramedullary plasmacytoma in the retroperitoneum. A 28-year-old man presented with obstructive jaundice and a retroperitoneal tumor. Ultrasound-guided biopsy confirmed that the lesion was a plasma cell neoplasm. A detailed investigation showed that no other sites were involved. The tumor got a moderate reduction following local irradiation, and a complete remission was achieved after 12 courses of adjuvant chemotherapy. Therefore, the possibility of a solitary extramedullary plasmacytoma should be considered in the differential diagnosis of obstructive jaundice without a history of multiple myeloma. Am. J. Hematol. 58:235–238, 1998. © 1998 Wiley-Liss, Inc.
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Authors: Irbaz Hameed, Mario Gaudino
Journal: JAMA Internal Medicine (2020)

Carolyn J. Crandall, MD, MS; Joseph Larson, MS; Nicole C. Wright, PhD; Deepika Laddu, PhD; Marcia L. Stefanick, PhD; Andrew M. Kaunitz, MD; Nelson B. Watts, MD; Jean Wactawski-Wende, PhD; Catherine R. Womack, MD; Karen C. Johnson, MD, MPH; Laura D. Carbone, MD, MS; Rebecca D. Jackson, MD; Kristine E. Ensrud, MD, MPH
Comparison of vascular nitric oxide production and systemic hemodynamics in cirrhosis versus prehepatic portal hypertension in rats
Authors: M Niederberger
Journal: Hepatology (1996)

Nitric oxide (NO) is postulated to play a role in the pathogenesis of arterial vasodilation in chronic portal hypertension. This present study investigates the relationship between systemic hemodynamics and the vascular production of NO, as estimated by measuring cyclic guanosine monophosphate (cGMP) in aortic tissue in two models of chronic portal hypertension in the rat: the partial portal vein ligation (PVL) model and CCl4-induced cirrhosis. NOS was also examined by Western blotting in aortic and mesenteric vessels. Sham-operated rats and rats given phenobarbital were used as controls. PVL rats and rats with cirrhosis and ascites showed a typical pattern of a hyperdynamic circulatory state, when compared with their respective controls: mean arterial pressure; PVL: 113 ± 2 versus 124 ± 2, P < .01 and cirrhotics: 103 ± 5 versus 130 ± 4 mm Hg, P < .01. Cardiac index; PVL: 32 ± 2 versus 26 ± 1, P < .01 and cirrhotics: 51 ± 3 versus 30 ± 1 mL · min-1 · 100 gm-1, P < .0001. Systemic vascular resistance; PVL: 3.7 ± 0.1 versus 4.9 ± 0.2, P < .01 and cirrhotics: 2.1 ± 0.2 versus 4.4 ± 0.2 mm Hg · min-1 100 g-1, P < .0001. Aortic cGMP was markedly increased in cirrhotic rats with ascites (728 ± 83 fmol/ mg protein) as compared with phenobarbital- treated controls (244 ± 31 fmol/mg, P < .001). This increase was abolished by chronic administration of N(omega)-nitro-L-arginine methyl ester. By contrast, PVL rats had an aortic cGMP concentration similar to sham-operated controls (282 ± 16 fmol/mg vs. 274 ± 33 fmol/mg, P = not significant) and significantly lower than that found in cirrhotic rats with ascites. Expression of cirrhotic aortic endothelial nitric oxide synthase (eNOS) was increased but PVL aortic eNOS did not differ from that of controls, whereas the mesenteric eNOS was increased in both PVL and cirrhotic rats as compared with the controls. These results suggest that vascular NO production is higher in cirrhotic rats than in PVL rats. This increased production may contribute to the more marked abnormalities in systemic hemodynamics seen in experimental cirrhosis as compared with PVL.
A Comparison of Prednisolone with Aspirin or Other Analgesics in the Treatment of Rheumatoid Arthritis: Medical Research Council and Nuffield Foundation Report
Authors: W Copeman, Charles Dodds, J Duthie, J Reid, H West
Journal: Annals of the Rheumatic Diseases (1960)

In 1955 the Joint Committee initiated a controlled therapeutic trial designed to compare the value of prednisolone with that of aspirin or other analgesics in the treatment of defined cases of rheumatoid arthritis.Eight centres participated and 84 patients entered the trial, a detailed description of which was published in a previous report (1959).During the first 2 years of treatment the patients receiving prednisolone showed an early significant improvement in both clinical and laboratory indices of inflammatory polyarthritis, and less progression of radiological signs of erosive joint disease, but in many patients treated with prednisolone a rise in agglutinating titre in the sheep cell agglutination test was noted and five patients had major complications (two psychoses, three peptic ulcers).
Tobacco Control
Authors: Michael Kent Ranson
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Examining the examinations for licensure and certification in medicine
Authors: J. J. Norcini
Journal: JAMA (1994)

In this issue ofThe Journal, Dawson and colleagues<sup>1</sup>report results of a study of the performance of men and women of various racial and ethnic backgrounds on the National Board of Medical Examiners (NBME) Part I examination. Differences among all groups were largely explained by education and performance before medical school. However, these factors did not account fully for the NBME Part I performance of women and Asian/Pacific Islander men. If confirmed by further research, the findings imply that the examination either unintentionally assessed aspects of performance unrelated to biomedical science or women and Asian/Pacific Islander men were deficient in the content tested. See also p 674. Dawson et al are appropriately cautious in interpreting their results. Despite attempts to control for differences in standardized test performance by using scores on the Medical College Admission Test as well as undergraduate major, science and nonscience hours, grade point averages,
Convictions and predictions on the role of internists in medical education
Authors: L. E. Young
Journal: JAMA (1971)

The 1970s already are recognized as a decade of crises in health care. Because of their numbers and their relatively central position in health care, internists have heavy responsibilities for dealing with these crises. I shall express my views on only one of these responsibilities, that of education in the health professions. My philosophy of education of physicians, both predoctoral and postdoctoral, is very simply stated. We learn chiefly from the study of patients as we are privileged to care for them, one by one, from the earliest clerkships of medical school to the last days of our professional careers. We read in textbooks, monographs and journals to seek answers to questions raised as we study and care for individual patients. The increasing flood of literature pouring into the library and across our desks does not overwhelm us if we learn how to use it with speed and diligence appropriate
Aligemeine Konstitutionslehre in naturwissenschaftlicher und medizinischer Betrachtung
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Health Values of the Seriously Ill
Authors: Richard Letvak
Journal: Annals of Internal Medicine (1996)

Letters15 January 1996Health Values of the Seriously IllRichard Letvak, MDRichard Letvak, MDHudson Headwaters Health Network; Warrensburg, NY 12885Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-124-2-199601150-00032 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:I read with interest the article by Tsevat and colleagues [1] on health values in seriously ill patients. I agree that an assessment of individual preferences and values in health care is long overdue, especially as our medical interventions become more costly and scarce. Expensive therapies such as dialysis and mechanical ventilation should be reserved for patients who are comfortable with their intensity.I am concerned, however, about the methods the authors used to study this issue. They used a time-tradeoff utility as a measure of a person's preference for quality (rather than quantity) of life. Patients ...REFERENCE1. Tsevat J, Cook EF, Green ML, Matchar DB, Dawson NV, Broste SK, et al. Health values of the seriously ill. Ann Intern Med. 1995; 122:514-20. Google Scholar Author, Article, and Disclosure InformationAuthors: Richard Letvak, MDAffiliations: Hudson Headwaters Health Network; Warrensburg, NY 12885 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 January 1996Volume 124, Issue 2Page: 279KeywordsCardiopulmonary resuscitationHealth careLife expectancyMedical dialysisPatientsPopulation statisticsQualitative studiesQuantitative analysisResearch designVentilators ePublished: 15 August 2000 Issue Published: 15 January 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Medical marriages
Authors: Julie Sladden
Journal: BMJ (2004)

Some brave doctors shared their views and tips with Julie Sladden about how to have a thriving (rather than merely surviving) marriage “Men are from Mars. Women are from Venus. Doctors are from Krypton,” according to Dr Greg Skipper from the Alabama Physician Health Program (see further information) and he has a point. Medical marriages face many of the same stresses and strains of any marriage but there are some unique issues that face both dual-doctor and doctor/non-doctor marriages. Although there is no evidence that divorce rates among medics are higher than other occupational groups,1 studies suggest that many medical marriages may be chronically unhappy, yet stable.2 This is not helped by the well documented inability of many doctors to seek help, especially when their relationship is in trouble.3 But it's not all bad news. A group of doctors, married to doctors and non-doctors, were brave enough to tell me their opinions on the issues affecting medicine and marriage, and here they offer some tips on how to have a thriving (rather than merely surviving) marriage. ### Box 1: Tips for a successful medical marriage
Abandon Internships; Establish New 'Primary Physicians,' Commission Urges
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Error in Results Section
Authors: Rahul Jindal, Peter Learn, Eric Elster
Journal: JAMA Surgery (2018)

Vatche G. Agopian, MD; Michael P. Harlander-Locke, MPH; Daniela Markovic, MS; Wethit Dumronggittigule, MD; Victor Xia, MD; Fady M. Kaldas, MD; Ali Zarrinpar, MD, PhD; Hasan Yersiz, MD; Douglas G. Farmer, MD; Jonathan R. Hiatt, MD; Ronald W. Busuttil, MD, PhD
Retirement of Asian GPs will cause problems for recruitment
Journal: BMJ (1999)

Nicotine nasal spray with patch is effective in stopping smoking On p 285 Blondal et al evaluate the efficacy of using a nicotine patch for 5 months with a nicotine spray for 1 year in stopping smoking.After 1 year, 27% of participants using the combined treatment were abstinent compared with 11% in the patch only group.Having access to nicotine in the nasal spray probably alleviated smoking urges.Five years after stopping treatment the difference in abstinence rates was double, emphasising the benefits of the combined treatment.
Comparison of Gas-Phase Free-Radical Populations in Tobacco Smoke and Model Systems by HPLC
Authors: Thomas M. Flicker, Sarah A. Green
Journal: Environmental Health Perspectives (2001)

We used an improved method for trapping carbon-centered radicals (.R) from the gas-phase to compare radical suites trapped from various tobacco smoke and model smoke systems. Using a nitroxide trap, 3-amino-2,2,5,5-tetramethyl-1-pyrrolidinyloxy (3AP), on solid support, we trapped radicals directly from the gas phase, washed them off the support, and analyzed them with HPLC. Separation of the trapped radicals showed that each tobacco type produced a unique radical suite of 4-10 distinct peaks. Gas mixtures used to model tobacco smoke consisted of nitric oxide, air, isoprene, and methanol. The model systems produced radical suites of four major and several minor peaks, two of which matched peaks in tobacco smoke chromatograms. Quantities of radicals trapped from tobacco smoke were: 54 +/- 2 nmol .R per Marlboro cigarette, 66 +/- 9 nmol .R per Djarum clove cigarette, and 185 +/- 9 nmol .R per Swisher Sweet cigar. In these experiments oxygen competes with the nitroxide trap for gas-phase radicals. A kinetic analysis of the O2 competition shows that actual radical concentrations in the smoke were approximately 100-fold higher than measured.
TUBERCULOSIS OF THE SPINAL CORD WITH PECULIAR CHANGES
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Parallel 14: Outcomes in Cirrhosis
Authors: Vasantha Kolachala, Abramowsky Carlos, Ming Shen, Alayna Feng, Allan Kirk, Nitika Gupta, John Gaetano, Dejan Micic, Archita Desai, Andrew Aron- Sohn, Nancy Reau, Helen Te, K Reddy, Donald Jensen, ; Gastroenterology, Andrew Aronsohn, Salvatore Piano, Elisa Favaretto, Silvano Fasolato, Carla Sca- Roni, Elisabetta Gola, Alessandra Brocca, Antonietta Sticca, Filippo Morando, Marta Cavallin, Antonietta Romano, Gia- Como Zanus, Angelo Gatta, Umberto Cillo, Paolo Angeli
Journal: Hepatology (2014)

body weight (42±1.2, vs. 24.6±0.6 grams; p<0.0001) and presence of hepatic steatosis by ORO stain.Splenocytes from HFD mice undergoing IRI demonstrated significant increase in CD4+ T cell activation markers, such as PD1 (p<0.0009),CD69(p<0.01),and CD62L(p<0.001), in addition to higher levels of serum ALT and significant increase in hepatocellular necrosis.The T cell proliferation marker Ki67 (p<0.0089), was significantly higher in HFD IRI as compared to lean IRI.Expression levels of L-selectin (p<0.03) but not P or E-selectin were elevated in HFD IRI.Increased cytokines such as IFNγ, IL-1a, IL-10, IL-6 and IL-17, suggested a pro-inflammatory milieu in HFD IRI.Blockade of L-selectin, lead to a significant attenuation of hepatocellular injury.Conclusion: A steatotic liver undergoing IRI is associated with elevation of adhesion molecule L-selectin along with activation and proliferation of CD4+ T cells, and a pro-inflammatory cytokine milieu.Blocking the adhesion molecule L-selectin leads to mitigation of hepatocellular injury, thus offering an important and clinically relevant therapeutic intervention in the increasingly prevalent clinical condition of IRI of fatty liver disease.
Evaluation of dried plasma spot on the cobas(r) plasma separation card as a sample type for hepatitis B virus load quantification on the cobas(r) 6800 system
Authors: Ariadna Rando, Fernando Rodrigo-Velásquez, Paula Salmerón, Mar Riveiro-Barciela, Rafael Esteban, Maria Buti, Ed G. Marins, Francisco Rodríguez-Friás
Journal: Journal of Hepatology (2020)
SUBCUTANEOUS FAT IN SCLEREMA
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ACTION OF MAGNESIUM SULPHATE ON THE GALLBLADDER
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal