tbuckley/cabot-search huggingface dataset:
Biology of the Internal Secretions. The Endocrine Factor in Development, in Subnormalities, in Neoplasms and Malignancy, in Nervous and Mental Diseases and in Heredity.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Responsible and irresponsible use of very-low-calorie diets in the treatment of obesity
Authors: T. A. Wadden
Journal: JAMA (1990)

AMERICA'S most celebrated weight loss was announced on November 15,1988, when Oprah Winfrey disclosed to her 18 million television viewers that she had lost 30.5 kg (67 lb) in 4 months by consuming a medically supervised very-low-calorie diet (<i>New York Times</i>. November 24,1988:B17). Ms Winfrey's announcement sparked a frenzy of interest among the nation's dieters, reminiscent of that which greeted the appearance of the liquid protein diets in 1976 and 1977<sup>1</sup>and the Cambridge Diet in the early 1980s.<sup>2</sup>Sadly, consumption of these diets was inadequately supervised; at least 58 deaths were reported among users of liquid protein products<sup>1,3</sup>and 6 deaths in persons who consumed the Cambridge Diet.<sup>2</sup> Current very-low-calorie diets that provide essential nutrients and high-quality proteins are unquestionably safer than their liquid protein predecessors, as noted in a timely report prepared by the American Medical Association's Council on Scientific Affairs.<sup>4</sup>But the
Conjunctival Myiasis
Authors: Alfred W. Pinkerton
Journal: JAMA (1971)

<h3>To the Editor.—</h3> When an attractive 20-year-old girl presents with a chief complaint of "I've got worms in my eye," do not jump to hasty conclusions and suspect a bad lysergic acid diethylamide (LSD) trip. The following case illustrates this point. The patient was hiking in the foothills of the Alborz mountains of northern Iran when she felt "something" go into her left eye. This was followed several hours later by intense pruritus, burning, and tearing. She noted "many small worms approximately one-sixteenth of an inch long with black heads and white tails" beneath her lower eyelid. This was associated with a "crawling" sensation. She presented at the hospital with the above complaint and a swollen tearing left eye. Nothing unusual could be visualized at that time by the examining physician. Appropriate treatment was prescribed for conjunctivitis and she was informed that "the worms probably didn't exist." Upon leaving the
For Whose Benefit Do We Write?
Authors: Edward F. Wells
Journal: JAMA (1899)

<h3>My Dear Doctor:</h3> —A medical friend of mine recently mentioned in a complimentary way an article you lately read before the Chicago Society of Internal Medicine, entitled "Pulmonary Tuberculosis." I am desirous of securing a scientific clinical report on paper on the therapeutic use of —. This preparation is, as you all know, ethic and scientific, and has been used extensively in phthisis. I would like an article of about a thousand words, and am willing to pay you for your careful observation and report. Of course I want the privilege of publishing the paper in the medical press. If you have the time and inclination to do this work for me, and need literature and samples, I will take pleasure in sending them to you. Thanking you in advance for an early reply, I am, very truly yours, -. Sincerely,
10. Parenteral Aminoglycosides
Journal: JAMA (1977)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Painful Shoulder in Patients with Pulmonary Tuberculosis
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SHALL ALCOHOL BE RECOGNIZED AS A FOOD?
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Methadone Overdose
Authors: David W. Fraser
Journal: JAMA (1971)

Two cases of overdose occurred with illicit use of methadone hydrochloride, intravenously injected. Pulmonary edema, myoglobinuria, and acute renal failure were prominent in these patients. They had injected themselves with pure methadone, which suggests that the overdose syndrome is caused by the narcotic itself and not by toxic diluents.
LIGATION OF THE INFERIOR VENA CAVA IN CARDIAC DECOMPENSATION
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DNR in the operating room. Not really a paradox
Authors: S. J. Youngner
Journal: JAMA (1991)

After nearly two decades of experience, the proper circumstances and procedures for implementing do-not-resuscitate (DNR) decisions have become a standard of care throughout our nation. This standard recognizes not only that cardiopulmonary resuscitation sometimes offers no benefit and may actually harm patients, but also that competent patients have a right to refuse it. Moreover, physicians have an obligation to discuss resuscitation status with patients and their families and to document those discussions and the resulting treatment plan in the medical record. In this issue of<i>JAMA</i>, Walker<sup>1</sup>identifies one important area of clinical practice where the application of DNR policy remains problematic— the operating room. At first glance, sending a DNR patient to the operating room may seem paradoxical. Yet, as Walker points out, terminal patients sometimes require palliative surgery. Furthermore, DNR patients need not be terminal; many of them live to leave the hospital
The functioning and well-being of depressed patients. Results from the Medical Outcomes Study
Authors: K. B. Wells
Journal: JAMA (1989)

We describe the functioning and well-being of patients with depression, relative to patients with chronic medical conditions or no chronic conditions. Data are from 11 242 outpatients in three health care provision systems in three US sites. Patients with either current depressive disorder or depressive symptoms in the absence of disorder tended to have worse physical, social, and role functioning, worse perceived current health, and greater bodily pain than did patients with no chronic conditions. The poor functioning uniquely associated with depressive symptoms, with or without depressive disorder, was comparable with or worse than that uniquely associated with eight major chronic medical conditions. For example, the unique association of days in bed with depressive symptoms was significantly greater than the comparable association with hypertension, diabetes, and arthritis. Depression and chronic medical conditions had unique and additive effects on patient functioning. (<i>JAMA</i>. 1989;262:914-919)
Intracardiac Self Insertion of a Darning Needle in a Psychiatric Patient
Authors: Avra Laarakker
Journal: Clinical Cardiology and Cardiovascular Interventions (2021)

Objective: We report a case of self inserted needle into the left ventricle of the heart and a description of our surgical intervention in a psychiatric patient without decision-making capacity. We discuss issues regarding obtaining consent in this patient with a sub-acute presentation, report our operative approach, and summarize a treatment approach based on a review of current literature. Methods: A PubMed search using terms “needle, “heart”, “insertion”, “intracardiac foreign object”, yielded 69 relevant papers. 67 of these were case reports yielding 72 individual cases. Age, gender, cause of the needle entry (Accidental Plus (A+), Intravenous Drug User [IVDU], Self-inflicted (SI)), type of needle, location in heart, neuropsychiatric history, treatment, and outcome were documented. Results: Within the SI category, there were a total of 28 cases, 89.3% had a neuropsychiatric history whereas only there were only 2 such patients in both the IVDU and A+ group. The location of the needle in the heart in all 72 cases was as follows: right ventricle 40.3%, other 20.8%, left ventricle 19.4 %, ventricle and interventricular septum 16.7% and the right and left atrium were each 1.4 %. In all three groups (n=72), 77.8% of patients underwent surgery, with 92.9% having a stable outcome. Conclusion: Our case and review demonstrates that management of such cases, particularly when active mental health issues are present, requires a case-by-case evaluation and treatment as a specific standard of care has not been established. Surgical intervention appears to be the preferred management regardless of presentation with good outcomes. Running Title: Intracardiac Self Insertion of a Darning Needle in a Psychiatric Patient
Delayed communication between hospitals and general practitioners.
Journal: BMJ (1988)

patients complain of depression, this mood change often becomes one of blunting of affect characterised by loss of feelings, especially towards loved ones.Irritability is another common affective change.The authors suggest that frontal lobe premotor lesions "may give rise to symptoms and signs other than personality changes," such as seizures and speech changes.When a patient is already being treated with an antidepressant the occurrence of seizures might easily be attributed to the drug.Vocal changes such as retarded and monotonous speech are well recognised to occur in depressed patients.2Difficulty in finding words is a common manifestation of impaired concentration, which itself is characteristic of depressive illness.The authors imply that depression is not a physical disease of the brain, thereby ignoring the research that has looked for an organic substrate for the erroneously named "functional" psychoses.Their seeming ignorance of the classical signs of depressive illness is worrying, not simply for patient care but also for undergraduate training.In this department we try to ensure that medical students have a broad grounding in both neurology and psychiatry and learn that diagnosis can be a subtle challenge that requires an open, receptive mind, free of prejudices.
Table of Contents
Authors: Imari Mimura, Masaomi Nangaku, Yosuke Hirakawa, Joseph Bonventre, Filippo Massa, Andreas Schedl, Andreas Kronbichler, David Jayne, Jeffrey Kopp, Martin Wilkie, Simon Davies, Allison Tong, Braden Manns, Angela Yee, Moon Wang, Brenda Hemmelgarn, David Wheeler, John Gill, Peter Tugwell, Robert Pecoits-Filho, Sally Crowe, Tess Harris, Wim Van Biesen, Wolfgang Winkelmayer, Adeera Levin, Aliza Thompson, Vlado Perkovic, Angela Ju, Talia Gutman, Amelie Bernier-Jean, Andrea Viecelli, Emma O'lone, Jenny Shen, Michelle Josephson, Yeoungjee Cho, David Johnson, Bénédicte Sautenet, Marcello Tonelli, Jonathan Craig, Matthieu Jamme, Cédric Rafat, Samuel Gaugain, Benjamin Chousterman, Krishnaswamy Sampathkumar, Thangaraj Mukuntharajan, Andrew Rajiv, Sivaraj Anandan, Romain Arrestier, Simon Mucha, Cyril Mousseaux, Inna Mohamadou
Journal: Kidney International (2018)
TCTAP A-153 Impact of Diabetes Mellitus on 5-Year Clinical Outcomes in Patients with Significant Coronary Artery Spasm; A Propensity Score Matching Study
Authors: Seung-Woon Rha, Byoung Geol Choi, Se Yeon Choi, Shaopeng Xu, Jabar Ali, Harris Ngow, Ji Bak Kim, Cheol Ung Choi, Eung Ju Kim, Dong Joo Oh
Journal: Journal of the American College of Cardiology (2015)
Gastrointestinal Pathophysiology
Authors: A. Dawson
Journal: BMJ (1975)

circumstances certain procedures are indi- cated.By itself it is an inadequate guide, but it should find a place in the library of any children's hospital.While there are many excellent parts, the book as a whole lacks cohesion and fails to convey the wholepatient approach, though many of the authors pay lip service to this ideal.
17-18 Trisomy Syndrome
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
New Device Approved for Use by Paraplegics
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Epidemiology and Transmission of HIV-2
Authors: Kevin M. De Cock
Journal: JAMA (1993)

Although human immunodeficiency virus type 1 (HIV-1) and HIV-2 share modes of transmission, their epidemiologic characteristics differ and international spread of HIV-2 has been very limited. Recently, the prevalence of infection with HIV-1 but not HIV-2 has increased rapidly in different West African countries, where HIV-2 was probably present earlier. Among 19 701 women of reproductive age tested in Abidjan, Ivory Coast, between 1988 and 1992, the prevalence of HIV-1 infection increased from 5.0% to 9.2%, while that of HIV-2 declined from 2.6% to 1.5%. Differences in viral load may be responsible: reported results of virus culture and polymerase chain reaction assays suggest that at high CD4<sup>+</sup>T-lymphocyte counts viral load is lower in HIV-2—infected than in HIV-1—infected persons; the efficacy of heterosexual and perinatal transmission of HIV-2 is less efficient than that of HIV-1 at this stage. At low (&lt;0.20×10<sup>9</sup>/L [&lt;200/μL]) CD4<sup>+</sup>T-lymphocyte counts, virus isolation is equally successful for both viruses, and the efficacy of heterosexual transmission is similar. Differences in HIV-1 and HIV-2 natural history are reflected in differences in viral load, that for HIV-2 being lower until immunodeficiency is severe. Differences in viral load throughout most of the natural history of infection appear to correlate with lower transmissibility of HIV-2 than HIV-1 and are the likeliest explanation for their markedly different global epidemiology. (<i>JAMA</i>. 1993;270:2083-2086)
Pulmonary Hypertension
Authors: Sanjiv J Shah
Journal: JAMA (2012)

Pulmonary hypertension (PH), defined as elevated pulmonary artery pressure, is common in the general population and associated with increased mortality. Accordingly, physicians commonly encounter patients with dyspnea, exercise intolerance, and/or right heart failure who have elevated pulmonary artery systolic pressure (PASP) on echocardiography. Although pulmonary arterial vasodilators may often be considered in this setting, these drugs have been predominantly tested in the subset of PH patients with pulmonary arterial hypertension (PAH). Elevated PASP alone is not sufficient for the diagnosis of PAH, and secondary causes of PASP elevation, most commonly left heart disease, are far more prevalent than isolated PAH. Treatment of this more common group of patients with PH due to left heart disease is challenging because there are few evidence-based treatment options, and pulmonary vasodilator therapy may lead to worsening symptoms. Therefore, improving symptoms and avoiding adverse outcomes in patients with PH requires the following: (1) understanding the optimal use of echocardiography for the diagnosis of PH; (2) recognizing the utility and proper interpretation of invasive hemodynamic testing prior to starting pulmonary vasodilator therapy; (3) differentiating PAH from pulmonary venous hypertension due to left heart disease; and (4) understanding the appropriate treatment strategies for PH and resultant right heart failure.
692 NITRIC OXIDE MIMICKS TRANSCRIPTIONAL AND POST-TRANSLATIONAL REGULATION DURING α-TOCOPHEROL CYTOPROTECTION AGAINST GLYCOCHENODEOXYCHOLATE-INDUCED CELL DEATH IN HEPATOCYTES
Authors: R. González, A. Cruz, P. López-Cillero, R. Fernández-Rodríguez, J. Bricefio, M.A. Gómez, S. Rufián, M. De la Mata, A. Martínez-Ruiz, J.J.G. Marín, J. Muntané
Journal: Journal of Hepatology (2011)
CAR T-cell Therapy Yields Durable Remissions in FL
Journal: Cancer Discovery (2019)

Abstract In a phase I/II study, chimeric antigen receptor T cells produced complete remissions in 88% of patients with refractory or relapsed follicular lymphoma, all of whom remained in remission after a median of 2 years of follow-up. The treatment induced cytokine release syndrome and neurotoxicity in 50% of patients, but none developed side effects more severe than grade 2.