Cost-Effectiveness of Screening for Microsatellite Instability To Detect Hereditary Nonpolyposis Colorectal Cancer
Journal: Annals of Internal Medicine (2001)

Summaries for Patients16 October 2001Cost-Effectiveness of Screening for Microsatellite Instability To Detect Hereditary Nonpolyposis Colorectal CancerSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-8_Part_1-200110160-00004 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Colorectal cancer is cancer of the colon (large intestine) or rectum. Some colorectal cancer is caused by an inherited cancer syndrome called hereditary nonpolyposis colorectal cancer (HNPCC). People in families with HNPCC have a higher than usual risk for colorectal and some other cancers. Genetic testing to detect a predisposition for hereditary colorectal cancer is now possible, but testing for the gene abnormalities (mutations) associated with HNPCC is too expensive to be done on all patients with colorectal cancer. Consequently, the National Cancer Institute (NCI) has published guidelines ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Cost-Effectiveness of Microsatellite Instability Screening as a Method for Detecting Hereditary Nonpolyposis Colorectal Cancer.” It is in the 16 October 2001 issue of Annals of Internal Medicine (volume 135, pages 577-588). The authors are SD Ramsey, L Clarke, R Etzioni, M Higashi, K Berry, and N Urban.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCost-Effectiveness of Microsatellite Instability Screening as a Method for Detecting Hereditary Nonpolyposis Colorectal Cancer Scott D. Ramsey , Lauren Clarke , Ruth Etzioni , Mitchell Higashi , Kristin Berry , and Nicole Urban Cost-Effectiveness of Microsatellite Instability Screening as a Method for Detecting Hereditary Nonpolyposis Colorectal Cancer Scott D. Ramsey , Lauren Clarke , Ruth Etzioni , Mitchell Higashi , Kristin Berry , and Nicole Urban Metrics 16 October 2001Volume 135, Issue 8_Part_1Page: I-48KeywordsCancer screeningChildrenColorectal cancerGenetic testingHealth careHereditary nonpolyposis colorectal cancerLarge intestineMutationRectumSimulation and modeling ePublished: 16 October 2001 Issue Published: 16 October 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...