tbuckley/cabot-search huggingface dataset:
ANHYDREMIC ACIDOSIS
Journal: JAMA (1925)

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Airflow, gas deposition, and lesion distribution in the nasal passages.
Authors: K T Morgan, T M Monticello
Journal: Environmental Health Perspectives (1990)

The nasal passages of laboratory animals and man are complex, and lesions induced in the delicate nasal lining by inhaled air pollutants vary considerably in location and nature. The distribution of nasal lesions is generally a consequence of regional deposition of the inhaled material, local tissue susceptibility, or a combination of these factors. Nasal uptake and regional deposition are are influenced by numerous factors including the physical and chemical properties of the inhaled material, such as water solubility and reactivity; airborne concentration and length of exposure; the presence of other air contaminants such as particulate matter; nasal metabolism, and blood and mucus flow. For certain highly water-soluble or reactive gases, nasal airflow patterns play a major role in determining lesion distribution. Studies of nasal airflow in rats and monkeys, using casting and molding techniques combined with a water-dye model, indicate that nasal airflow patterns are responsible for characteristic differences in the distribution of nasal lesions induced by formaldehyde in these species. Local tissue susceptibility is also a complex issue that may be a consequence of many factors, including physiologic and metabolic characteristics of the diverse cell populations that comprise each of the major epithelial types lining the airways. Identification of the principal factors that influence the distribution and nature of nasal lesions is important when attempting the difficult process of determining potential human risks using data derived from laboratory animals. Toxicologic pathologists can contribute to this process by carefully identifying the site and nature of nasal lesions induced by inhaled materials.
H2O2 For Colon Lavage In Infants . . . . . A Danger?
Journal: JAMA (1966)

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Stenosis of ileum due to mesenteric laceration
Authors: C. H. Urban
Journal: JAMA (1968)

<h3>To the Editor:—</h3> May I offer a reply that disagrees with an answer given in the QUESTION AND ANSWERS section ofThe Journal(<b>202</b>:1060, 1967)? The question was: "Does exercise have an important function in weight control?" I believe it does, both in maintaining an appropriate weight and in reducing excessive fatness. For years we have seen tables that assign different caloric requirements for sedentary and for strenuous occupations; for centuries farmers have penned up livestock they wish to fatten. Sitting clearly burns up fewer calories than walking; and fatness most certainly is affected by the proportion between the calories taken in and the calories expended. It has frequently been stated that, since it takes a 35-mile walk to lose a pound of fat, exercise is of little value in the treatment of obesity. However, such a statement has no relevance to a sensible program of daily exercise. Just
Rewards and hazards of selective renal arteriography
Authors: I. L. Bunnell
Journal: JAMA (1965)

Selective renal arteriography is a necessary technic in the present-day evaluation of patients with high blood pressure. It provides a high diagnostic yield of renal-artery occlusive lesions with low morbidity. In a total series of 127 patients, 32 patients were found to have occlusive renal-artery lesions; 12 were operated upon: of these, seven were cured and three significantly improved. Selective renal arteriography, in our laboratory, is associated with no mortality and a morbidity of 6%. Glomerular filtration rate and renal plasma flow were unimpaired after selective renal arteriography.
THE SEMI-CENTENNIAL OF THE AMERICAN MEDICAL ASSOCIATION.
Journal: JAMA (1895)

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Authors' reply
Authors: N R Qureshi, N M Rahman, F V Gleeson
Journal: Thorax (2009)

in a gradual reduction in the number of radiology departmental procedures from 63 to 17 per annum.A recent audit of our activity showed that over a period of 18 months, 102 bedside TUS procedures were performed (table 1).The main indications for TUS included confirmation of the presence of a small pleural effusion, and guidance for pleural procedures.In 71 cases TUS confirmed the radiological findings, with discordant findings in the remaining 31 cases.The TUS findings were crucial in 30 cases, showing either an absent or a very small pleural effusion, not suitable for an invasive pleural procedure.In a further 10 patients TUS facilitated case monitoring.TUS provided guidance in all cases requiring a pleural procedure; 48 and 8 for chest drain insertion and needle aspiration, respectively.None of the subsequent procedures had any associated complications.Use of TUS decreases the complications associated with pleural procedures, 2 which may result in serious harm or even death. 3 Recent British Thoracic Society advice on chest drain insertion has advocated the use of ultrasound image guidance. 4 Our experience confirms that TUS can be employed by respiratory physicians both as a diagnostic aid and for guiding procedures, and not just in major centres.Cost benefits also accrue from a decrease in the number of scans performed in the radiology department, and in the time involved in waiting for them.Therefore, we would support increased use of this technique by respiratory physicians, after appropriate training, for which guidance already exists. 5 The recognition of the characteristics of malignant pleural effusion as described by Qureshi and colleagues may, however, require a higher level of expertise in the interpretation of TUS findings, as well as the use of high frequency ultrasound probes. 2This may have training implications for respiratory physicians if we wish to maximise the potential benefits of TUS in diagnosing malignant pleural effusions, rather than limit the technique to the support of diagnosis of pleural effusions and safer invasive procedures.
American Journal of Gastroenterology, New York
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Errors in Group Information and Additional Contributions
Authors: Frank Schalkwijk, David Van Bodegom, Noel Mueller
Journal: JAMA Cardiology (2019)

Judith S. Hochman, MD; Harmony R. Reynolds, MD; Sripal Bangalore, MD, MHA; Sean M. O’Brien, PhD; Karen P. Alexander, MD; Roxy Senior, MD, DM; William E. Boden, MD; Gregg W. Stone, MD; Shaun G. Goodman, MD, MSc; Renato D. Lopes, MD, PhD; Jose Lopez-Sendon, MD, PhD; Harvey D. White, MB ChB, DSc; Aldo P. Maggioni, MD; Leslee J. Shaw, PhD; James K. Min, MD; Michael H. Picard, MD; Daniel S. Berman, MD; Bernard R. Chaitman, MD; Daniel B. Mark, MD, MPH; John A. Spertus, MD, MPH; Derek D. Cyr, PhD; Balram Bhargava, MD, DM; Witold Ruzyllo, MD, PhD; Gurpreet S. Wander, DM; Alexander M. Chernyavskiy, MD; Yves D. Rosenberg, MD, MPH; David J. Maron, MD; for the ISCHEMIA Research Group
Defective corticotropin-releasing hormone mediated neuroendocrine and behavioral responses in cholestatic rats: Implications for cholestatic liver disease-related sickness behaviors*1
Authors: M SWAIN
Journal: Hepatology (1995)

Nonspecific systemic complaints are commonly encountered in patients with cholestatic liver diseases. However, the cause of these symptoms is poorly understood. Because corticotropin-releasing hormone (CRH) has been implicated as a mediator of sickness-related systemic symptoms, we examined CRH-mediated neuroendocrine and behavioral responses in rats with cholestasis due to bile duct resection (BDR) or sham resected (sham) controls. BDR and sham rats were placed individually in an open field apparatus, and the number of inner and outer squares entered, as well as the number of fecal boli produced, counted over a 5-minute period. Fecal boli production and inner squares entered are dependent on central CRH release. BDR and sham rats entered the same number of outer squares; however, BDR rats entered significantly fewer inner squares and produced fewer fecal boli than did sham rats, suggesting defective central CRH release in BDR rats. Immediately after exposure to the open field, rats were killed and blood adrenocorticotropic hormone (ACTH) levels measured. ACTH release is dependent on central CRH release. BDR rats demonstrated significantly lower plasma ACTH levels after exposure to an open field than did sham animals. To further explore the central CRH defect in BDR rats, hypothalamic CRH contents were determined in BDR and sham rats with and without exposure to restraint stress. BDR rats had significantly lower basal hypotha. lamic CRH levels than sham animals, and CRH levels did not further decrease in BDR rats with restraint stress (as normally occurs). These results are consistent with defective CRH-mediated responses in cholestatic rats. Aberrant CRH-mediated responses may contribute, at least in part, to some of the nonspecific systemic complaints in patients with cholestatic liver diseases.
Clinical Roentgenology of the Alimentary Tract
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstracts
Journal: Annals of the Rheumatic Diseases (1969)

The purpose of this study was to evaluate the effect of early ambulation in the management of children with a first attack of rheumatic fever who also received 12 weeks of prednisone therapy.The design of the investigation is very similar to previous studies by this group.It had to be a first attack of rheumatic fever of not more than 18 days' duration in a patient who had previously not re- ceived therapeutic doses of either corticosteroids or salicylates.122 patients were studied for 15 weeks and 120 for one year.They were divided into two random groups: rest in bed and activity.The former were kept in bed throughout the 12 weeks of prednisone therapy and for an additional 3 weeks after its cessation and were then progressively allowed to do more.The latter were kept in bed until the erythrocyte sedimentation rate had returned to normal, and were then allowed full activity within the hospital.Initially the two groups were comparable with regard to the presence of carditis, which was also assessed by murmurs graded from 1 to 4, polyarthritis, erythema annulare, and the minor manifestations of rheumatic fever.Both progressed similarly except that the ESR tended to be slightly higher in those patients who were treated by activity, but at 15 weeks from the onset there was no difference with regard to carditis in the group resting in bed com- pared with the activity group.Neither could any difference be detected at the end of the one year followup.The author suggests that, in patients treated with prednisone, prolonged rest in bed after the subsidence of the acute inflammatory reaction does not materially influence the amount of residual cardiac damage.
The Career of Dr. Weaver.
Journal: JAMA (1913)

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Editorial Board
Authors: Bruce Thiers, Dirk Elston, Detra Davis, Jack Lesher, Kenneth Katz, Mary Spellman, Jeffrey Weinberg, Dermatologic Surgery, Clifford Perlis, Julie Prendiville, Frcpc Dermatopathology, John Maize, Robert Dellavalle, J Smith, Editors Emeritus, Richard Dobson, Jeffrey Bernhard, Calvin Mccall, Brett Sloan, James Solomon, Stephen Tyring, George Hruza, Pediatric Dermatology, Kelly Cordoro, Dermatopathology Carlson, Tammie Ferringer, Cyberdermatology Consultant, Daniel Siegel, Clara Kim, Salvador Arias-Santiago, April Armstrong, Bryan Anderson, Trisha Beute, John Binhlam, Diana Bolotin, Markus Braun-Falco, Nooshin Brinster, Patrick Carrington, Zoe Draelos, Nananamibia Duffy, Laura Ferris, David Fivenson, Joel Gelfand, Camille Introcaso, Nathaniel Jellinek, Jonathan Kantor, Matthew Kanzler, Kevin Kia, Nikki Levin, A2 December, J Am, Acad Dermatol
Journal: Journal of the American Academy of Dermatology (2013)
The Practice of Medicine.
Journal: JAMA (1910)

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THE JOURNAL SPECIAL TRAIN TO DENVER.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phase II Study of Single Agent Cetuximab in Kras G13D Mutant Metastatic Colorectal Cancer (MCRC)
Authors: M. Schirripa, S. Lonardi, C. Cremolini, F. Loupakis, L. Salvatore, F. Bergamo, C. Antoniotti, A. Roma, R. Bertorelle, F. Marmorino, D. Rossini, G. Pasquini, F. Zoratto, G. Masi, V. Zagonel, A. Falcone
Journal: Annals of Oncology (2014)
Change of Dosing Regimen for Malaria Prophylaxis with Mefloquine
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal