tbuckley/cabot-search huggingface dataset:
Table of Contents
Authors: Yunyoung Chang, Ganary Dabiri, Elizabeth Damstetter, Emily Ebot, Jennifer Powers, Tania Phillips, Molly Wanner, Fernanda Sakamoto, Mathew Avram, R Anderson, Henry Chan, Murad Alam, Zeina Tannous, Alexander Maley, Maxine Warren, Ilyse Haberman, Robert Swerlick, Bhairavi Kharod-Dholakia, Ron Feldman, Kim Papp, James Krueger, Steven Feldman, Richard Langley, Diamant Thaci, Hideshi Torii, Stephen Tyring, Robert Wolk, Annie Gardner, Charles Mebus, Huaming Tan, Yingchun Luo, Pankaj Gupta, Lotus Mallbris, Svitlana Tatulych, Bruce Strober, Robert Bissonnette, David Fiorentino, Alexa Kimball, Luigi Naldi, Neil Shear, Kavitha Goyal, Steven Fakharzadeh, Stephen Calabro, Wayne Langholff, Yin You, Claudia Galindo, Seina Lee, Mark Lebwohl, Athanassios Kolivras, Curtis Thompson, Lawrence Kuklinski, Jinah Kim
Journal: Journal of the American Academy of Dermatology (2016)
Vitamin E cannot protect myocardium against oxidative damage
Authors: H.H. Klein
Journal: Cardiovascular Research (1995)

Vitamin E cannot protect myocardium against oxidative damage H.H. Klein H.H. Klein * Abteilung für Kardiologie, Universitätsklinik Lahnberge, 35033 Marburg, Germany *Corresponding author: Tel. (+49-6781) 661546; Fax (+49-6781) 661559. Search for other works by this author on: Oxford Academic PubMed Google Scholar Cardiovascular Research, Volume 30, Issue 1, July 1995, Pages 156–157, https://doi.org/10.1016/S0008-6363(95)00003-8 Published: 01 July 1995
A Case-Control Study of Lung Cancer with Special Reference to Asbestos Exposure
Authors: M. Minowa, S. Hatano, M. Ashizawa, H. Oguro, H. Naruhashi, M. Suzuki, K. Mitoku, M. Miwa, C. Wakamatsu, Y. Yasuda, K. Shirai, H. Miura
Journal: Environmental Health Perspectives (1991)

A case-control study oflung cancer was carried out in
Questions and Answers
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue Access Provided by Korea University Medical Library JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account
Reaction Products of Aquatic Humic Substances with Chlorine
Authors: J. D. Johnson, R. F. Christman, D. L. Norwood, D. S. Millington
Journal: Environmental Health Perspectives (1982)

A major concern of the chlorination of aquatic humic materials is the ubiquitous production of trihalomethanes. A large number of other chlorinated organic compounds, however, have been shown to be formed by chlorine's reaction with humic substances. In this study, humic material was concentrated from a coastal North Carolina lake and chlorinated at a chlorine to carbon mole ratio of 1.5 at pH 12. A high pH was necessary for complete dissolution of the humic material and for production of adequate quantities of oxidation and chlorination products for extraction, separation and mass spectrometric identification. After concentration in ether, samples were methylated, separated with a 50-m OV-17 glass capillary column or a 25 m SP-2100 fused-silica column and identified. A Hewlett-Packard 5710A gas chromatograph interfaced to a VG Micromass 7070F double-focusing mass spectrometer was used. Low resolution, accurate mass measurements were made with a combined EI-Cl source. The ability to do low resolution, accurate mass measurements made possible a rapid scan function necessary for capillary column gas chromatography. Accurate mass measurements allowed increased confidence in the identification of compounds, most of which are not available as standards. The products identified in these studies were chlorinated aliphatic straight-chain acids dominated by di- and trichloroacetic acid and the chlorinated dicarboxylic acids: succinic, fumaric and maleic acids. Chlorinated and unchlorinated aliphatic mono- and dicarboxylic acids and unchlorinated polycarboxylic aromatic acids comprise the remaining bulk of the compounds identified.
Multiple Myeloma
Authors: Kenneth C. Anderson, Melissa Alsina, William Bensinger, J. Sybil Biermann, Asher Chanan-Khan, Adam D. Cohen, Steven Devine, Benjamin Djulbegovic, Edward A. Faber, Cristina Gasparetto, Carol Ann Huff, Adetola Kassim, Bruno C. Medeiros, Ruby Meredith, Noopur Raje, Jeffrey Schriber, Seema Singhal, George Somlo, Keith Stockerl-Goldstein, Steven P. Treon, Guido Tricot, Donna M. Weber, Joachim Yahalom, Furhan Yunus
Journal: Journal of the National Comprehensive Cancer Network (2011)

Multiple myeloma (MM) is a malignant neoplasm of plasma cells that accumulate in bone marrow, leading to bone destruction and marrow failure.The American Cancer Society estimates 20,520 new cases of MM will be diagnosed in the United States in 2011, including 11,400 cases in men and 9,120 in women, with an estimated 10,610 deaths. 1 The mean age of affected individuals is 62 years for men (75% older than 70 years) and 61 years for women (79% older than 70 years).The treatment of MM has dramatically improved over the past decade.The 5-year survival rate reported in the Surveillance, Epidemiology and End Results database increased from 25% in 1975 to 34% in 2003 because of newer and more effective treatment options. 2,
DENMARK
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Results and implications of the AMA-APA Physician Mortality Project. Stage II. Council on Scientific Affairs
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SCIDOT-41. NANOTHERAPEUTIC TARGETING OF TUMOR ENDOTHELIUM FOR ENHANCING DRUG DELIVERY PAST THE BLOOD-BRAIN BARRIER
Authors: Hiroto Kiguchi, Mandana Manzari, Jake Vaynshteyn, Jeffrey Gerwin, Daniel Tylawsky, Na Li, Janki Shah, Yosi Shamay, Matthew Greenblatt, Daniel Heller, G Praveen Raju
Journal: Neuro-Oncology (2019)

Abstract OBJECTIVE The Sonic Hedgehog (SHH) medulloblastoma subgroup accounts for ~25% of all cases and has an intermediate prognosis. Current conventional therapies result in devastating morbidities including intellectual disability and secondary malignancies. Although molecularly targeted agents that inhibit the SHH pathway have demonstrated clinical efficacy, recent studies have shown on-target secondary toxicities on bone development suggesting new therapeutic approaches are needed. METHODS We investigated the efficacy of the SHH pathway inhibitor, Vismodegib packaged in a fucoidan-based nanoparticle (Fi-Vis) that targets P-selectin, a protein overexpressed on vascular endothelial cells and induced by low-dose ionizing radiation (XRT) in a time- and dose-dependent manner. This P-selectin targeting nanoparticle drug delivery system shows selectivity toward tumor vasculature and not normal brain vasculature in a genetic SHH medulloblastoma mouse model as assessed by ex vivo infrared imaging and two-photon intravital imaging. RESULTS Quantitative RT-PCR analysis of SHH medulloblastoma tissue following single dose XRT and Fi-Vis treatment (10mg/kg) showed a synergistic inhibition of Gli1 expression (&gt;90% target inhibition). Furthermore, we demonstrate that very low dose XRT (0.25Gy) can induce P-selectin expression specifically within MB tumor vasculature and synergize with low dose Fi-Vis (10mg/kg) to significantly enhance mouse survival (p&lt;0.01) when compared to radiation or Fi-Vis alone. Furthermore, assessment of bone toxicity using micro-CT and histological analysis following Fi-Vis administration in postnatal (P10) mice shows no bone toxicity when compared to free Vismodegib. Finally, in vitro studies using mouse brain endothelial cells suggest at least in part a caveolin-1 mediated transcytosis mechanism of crossing the endothelial blood-brain barrier. CONCLUSIONS These data suggest applicability of combined XRT and tumor vasculature-targeted nanotherapeutic dose de-escalation strategies for SHH medulloblastoma with implications for other pediatric and adult brain tumors.
Operative Neurosurgery
Authors: A. Earl Walker
Journal: JAMA (1964)

The first edition of this work, written by Drs. Gurdjian and Webster, has been revised by the former with the assistance of Drs. E. D. Gardner, W. G. Hardy, D. W. Lindner, L. M. Thomas, and J. E. Webster. The volume retains the general format of the original work. A short introduction is devoted to the preparation of the patient, to the anesthesia and the instrumentation of operation. The surgery of the nervous system is discussed under the topical headings of head, spine, and autonomic and peripheral nerves. The description of each technique is preceded by a brief historical account of the development of the operation and the symptomatology of the condition for which the procedure is indicated. The text related to the operation is printed on the verso page with the illustrations on the recto for the convenience of the reader. This second edition has been enlarged by the
Glucorrhea revisited. Prolonged promulgation of another plastic pearl
Authors: H. F. Hull
Journal: JAMA (1975)

Glucose oxidase test strips were used to evaluate the presence of glucose in nasal secretions and tears in a group of normal children. Substantial amounts of glucose were present in 15 of 17 samples of nasal discharge and 10 of 15 samples of tears. The use of glucose oxidase test strips for diagnosis of cerebrospinal fluid rhinorrhea, therefore, is without merit. (<i>JAMA</i>234:1052-1053, 1975)
<i>Helicobacter pylori</i> Infection and the Risk for Heart Attacks in Men
Journal: Annals of Internal Medicine (2001)

Summaries for Patients7 August 2001Helicobacter pylori Infection and the Risk for Heart Attacks in MenSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-3-200108070-00006 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Heart attacks result when blockages form in the arteries that supply blood to the heart (the coronary arteries). Chronic infection with certain bacteria may be among the many factors that contribute to these blockages, possibly by causing inflammation of the blood vessel walls, which damages the walls and allows blockages to form. Chronic infections like this do not cause people to feel sick but can be detected using blood tests that tell whether the person has been exposed to the infection in the past. Helicobacter pylori (H. pylori) ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “A Prospective Study of Helicobacter pylori Seropositivity and the Risk for Future Myocardial Infarction among Socioeconomically Similar U.S. Men.” It is in the 7 August 2001 issue of Annals of Internal Medicine (volume 135, pages 184-188). The authors are PM Ridker, J Danesh, L Youngman, R Collins, MJ Stampfer, R Peto, and CH Hennekens.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoA Prospective Study of Helicobacter pylori Seropositivity and the Risk for Future Myocardial Infarction among Socioeconomically Similar U.S. Men Paul M. Ridker , John Danesh , Linda Youngman , Rory Collins , Meir J. Stampfer , Richard Peto , and Charles H. Hennekens Metrics 7 August 2001Volume 135, Issue 3Page: I-28KeywordsBacteriaBloodCardiovascular therapyForecastingHealth economicsHelicobacter pyloriHematologic testsInfectious diseasesLongitudinal studiesMyocardial infarction ePublished: 7 August 2001 Issue Published: 7 August 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Sectarian medicine
Authors: N. Gevitz
Journal: JAMA (1987)

IN<i>THE Devil's Dictionary</i>, Ambrose Bierce defined a "homeopath" as "the humorist of the medical profession."<sup>1</sup>To Bierce, this practitioner with his peculiar notions regarding the selection and administration of drugs may have been an unintentionally funny figure, but to orthodox physicians who combated these opponents through the years, homeopathy was anything but a laughing matter. Neither were other sectarian rivals who have flourished in the United States during the past 150 years. The term "sect" has been applied to those groups (whether inside or outside the orthodox medical tradition) who have challenged the legitimacy and value of accepted therapeutic principles and practices. Such groups have championed the use of alternative modes of healing based on a set of doctrines that they initially regard as laws. Given their radical beliefs and approaches, these sectarians have had to form separate institutions and associations to support their continued existence and growth.
The human, societal, and scientific legacy of cholera
Authors: William B. Greenough
Journal: Journal of Clinical Investigation (2004)

The recent history of research on cholera illustrates the importance of establishing research and care facilities equipped with advanced technologies at locations where specific health problems exist. It is in such settings, where scientific research is often considered difficult due to poverty and the lack of essential infrastructure, that investigators from many countries are able to make important advances. On this, the 25th anniversary of the founding of the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), this article seeks to recount the Centre’s demonstration of how high-quality research on important global health issues, including cholera, can be accomplished in conditions that may be considered by many as unsuitable for scientific research.
The periodontal membrane in systemic sclerosis
Authors: N.R. Rowell, F.E. Hopper
Journal: British Journal of Dermatology (1975)

Journal Article The periodontal membrane in systemic sclerosis Get access N.R. Rowell, N.R. Rowell Departments of Dermatology and Dentistry, University of Leeds Search for other works by this author on: Oxford Academic Google Scholar F.E. Hopper F.E. Hopper Departments of Dermatology and Dentistry, University of Leeds Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 93, Issue s11, 1 July 1975, Page 23, https://doi.org/10.1111/j.1365-2133.1975.tb06773.x Published: 01 July 1975
Should all casualty radiographs be reviewed?
Authors: P M Channells, J Wardrope
Journal: BMJ (1985)

The effect on the management of patients of routine reporting of casualty radiographs by radiologists was reviewed.The overall prevalence of error by casualty doctors was 6*2%.Many of these errors, however, were trivial and did not alter treatment.In only 1 1% of the cases reviewed did the report of x ray films appreciably alter the management ofthe patient.A severity score was introduced to highlight those anatomical areas in which important lesions were overlooked most often.Radiologists'
Rochalimaea henselae Infection
Authors: Jane E. Koehler
Journal: JAMA (1994)

<h3>Objective.</h3> —To determine the reservoir and vector(s) for<i>Rochalimaea henselae</i>, a causative agent of bacillary angiomatosis (BA) and cat scratch disease, and to estimate the percentage of domestic cats with<i>R henselae</i>bacteremia in the Greater San Francisco Bay Region of Northern California. <h3>Design.</h3> —Hospital-based survey of patients diagnosed with BA who also had significant exposure to at least one pet cat, as well as a convenience sampling of pet or impounded cats for prevalence of<i>Rochalimaea</i>bacteremia. <h3>Setting.</h3> —Community and university hospitals and clinics; veterinary clinics treating privately owned or impounded cats. <h3>Patients.</h3> —Patients with or without human immunodeficiency virus infection, with biopsy-confirmed BA, who had prolonged exposure to pet cats prior to developing BA. <h3>Main Outcome Measures.</h3> —Cultures and laboratory studies were performed on blood drawn from pet cats associated with patients with BA. The<i>Rochalimaea</i>species infecting pet cats and fleas and causing the BA lesions in human contacts of these cats was identified by culture, polymerase chain reaction—restriction fragment length polymorphism analysis, and DNA sequencing. The presence of<i>R henselae</i>bacteremia in pet cats was documented, and predictor variables for culture positivity were evaluated. <h3>Results.</h3> —Four patients diagnosed with BA who had prolonged contact with seven pet cats were identified. The<i>Rochalimaea</i>species causing BA lesions in these patients was determined to be<i>R henselae</i>. The seven pet cats were found to be bacteremic with<i>R henselae</i>; this bacterium was also detected in fleas taken from an infected cat by both direct culture and polymerase chain reaction. Blood samples were cultured from pet and impounded cats (N=61) in the Greater San Francisco Bay Region, and<i>R henselae</i>was isolated from 41% (25/61) of these cats. <h3>Conclusion.</h3> —We have documented that the domestic cat serves as a major persistent reservoir for<i>R henselae</i>, with prolonged, asymptomatic bacteremia from which humans, especially the immunocompromised, may acquire potentially serious infections. Antibiotic treatment of infected cats and control of flea infestation are potential strategies for decreasing human exposure to<i>R henselae</i>. (<i>JAMA</i>. 1994;271:531-535)
High Hopes
Authors: Abigail Zuger
Journal: JAMA (1989)

Jerry Silver wants to live. Propped up against his pillows, his breath rasping across his swollen belly, he makes his point once again for the doctor sitting on the side of his bed. "You mean," he says, "that suppose I get even sicker and go into a coma and have to be put on a respirator, do I want that? You mean that suppose my heart stops and they have to shock me and beat on me to start it again, do I want that?" The doctor nods, wearily. "Of course I do," says Jerry. "Suppose they find a cure, tomorrow. I want to be here." They've gone over this ground 20 times in the last three weeks, as Jerry grows weaker and the chances he ever leaves the hospital grow more and more remote. Seven years ago, during the surgery that saved his life after his heart attack, Jerry
Adult Blood Lead Epidemiology and Surveillance
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Two-Stage Model for Breast Carcinogenesis in Females
Authors: P. Emmelot, E. Scherer
Journal: JNCI Journal of the National Cancer Institute (1981)

Two-Stage Model for Breast Carcinogenesis in Females Get access P. Emmelot, P. Emmelot Division of Chemical Carcinogenesis Antoni Van Leeuwenhoek-Huis The Netherlands Cancer Institute1066 CX Amsterdam, The Netherlands Search for other works by this author on: Oxford Academic PubMed Google Scholar E. Scherer E. Scherer Division of Chemical Carcinogenesis Antoni Van Leeuwenhoek-Huis The Netherlands Cancer Institute1066 CX Amsterdam, The Netherlands Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 67, Issue 4, October 1981, Pages 743–745, https://doi.org/10.1093/jnci/67.4.743-a Published: 01 October 1981