tbuckley/cabot-search huggingface dataset:
Correction: The Incidence of Dementia in England and Wales: Findings from the Five Identical Sites of the MRC CFA Study
Authors: Fiona Matthews, Carol Brayne
Journal: PLoS Medicine (2005)

In the third paragraph of the section "Neglected-Disease R&D Activity," the sentence "Nearly one-third of these projects are at the clinical trial stage, including seven drugs now in Phase III trials…" should read instead "Nearly one-third of these projects are at the clinical trial stage, including six drugs now in Phase III trials…."
I have been a senior house officer (SHO) in obstetrics and gynaecology for the past 12 months and have done part 1 membership of the Royal College of Obstetricians and Gynaecologists (MRCOG). I am interested in pursuing a career in genitourinary medicine. Can you help with the following queries? I cannot take MRCOG part 2 as I have to do three more years of training in obstetrics and gynaecology. I don't want to go on to second on-call posts as I am not interested in obstetrics and gynaecology…
Authors: Phillip Kell
Journal: BMJ (2006)

Have a career or related problem that needs answering? Can9t find the right person to point you in the right direction? Log on to the Advice Zone for reliable medical careers advice. You can post a question or see if one of our 300 advisers has already answered a similar question. Here is a selection of questions and answers posted on the site. <b>www.bmjcareers.com/advicezone</b>
NEUROLOGY AND PSYCHIATRY IN AMERICA.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ANTIVISECTIONISTS AND MISREPRESENTATION.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nuclear Factor of Activated T-Cells (NFAT1): Potential Novel Target in T-Cell Acute Lymphocytic Leukemia (T-ALL)
Authors: Hongyan Lu, Shicheng Yang, Xiao Huang, Harun El Masri, Paul C Trampont, Amandeep Salhotra, James G Farmar, Alexander J Wendling, Mary J Laughlin
Journal: Blood (2011)
Hypotension.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hypoalbuminemia, Not Hyperalbuminemia
Authors: J Almeida, R Hasselback, A Ham
Journal: JAMA (1964)

Modified negative staining technique and electron micro¬ scopy were used to demonstrate fragile virus particles with a surrounding membranous sack and an internal filamentous component in the blood of two patients with acute leukemia.No particles of this type were seen in the blood of four other patients with acute leukemia or in the blood of six normal individuals.Some of the filaments in the internal components of the virus-like particles appeared to have a double helix.Since passenger viruses can be present in ma¬
Physiology of marathon running
Authors: D. L. Costill
Journal: JAMA (1972)

Like most endurance athletes, marathon runners are characterized by their highly developed aerobic capacities (V̇o<sub>2</sub>max) and an ability to tolerate high rates of energy expenditure (70% to 90% V̇o<sub>2</sub>max) without accumulating blood lactate. During marathon competition these men must alter their speed to compensate for the detrimental effects of uneven terrain, wind resistance, and thermal stress. Such factors add to the circulatory and metabolic demands of running. Heat produced in the active muscles must be transported to the body surface via the circulatory system and subsequently dissipated to the environment. Since the major responsibility of circulation is to transport nutrients and metabolic wastes, increasing the environmental heat stress will overload the circulatory system, thereby reducing performance and posing a risk to the runners' health.
<i>Announcement: </i>National Kidney Month — March 2017
Authors: Jiaquan Xu, Sherry Murphy, Kenneth Kochanek, Elizabeth Arias
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

Each year, March is designated National Kidney Month to raise awareness about the prevention and early detection of kidney disease. In the United States, kidney disease is the ninth leading cause of death (1). Approximately one in seven (15%) U.S. adults aged ≥20 years are estimated to have chronic kidney disease, most of whom are unaware of their condition (2). If left untreated, chronic kidney disease can lead to kidney failure, requiring dialysis or transplantation for survival (3).
Hypothyroidism Followed by Hyperthyroidism
Authors: Martin A. Hochstein
Journal: JAMA (1977)

THE PROGRESSION from hypothyroidism to thyrotoxicosis, although uncommon, has been documented in the past.<sup>1</sup>In most of these reports, the initial phase of hypothyroidism had been caused by primary thyroid failure. A similar sequence following Hashimoto thyroiditis is, indeed, rare. To our knowledge, there have been no reports of this phenomenon in the literature other than the patient described by Zellmann et al<sup>2</sup>in 1966. In this case, a hypothyroid patient with possible Hashimoto thyroiditis became hyperthyroid two years later. Interestingly, the patient had proptosis early in the course of the illness while he was hypothyroid. <h3>Report of a Case</h3> A 36-year-old man had been in excellent health until 1969, when he began to feel apathetic and noted that his eyes "looked queer." The symptoms progressed until June 1970, when he was first seen by a physician who believed that he was clinically hypothyroid. The pulse was 48
Primary cytomegalovirus infection in pregnancy. Incidence, transmission to fetus, and clinical outcome
Authors: S. Stagno
Journal: JAMA (1986)

We studied 16 218 pregnant women from two income groups to determine the incidence of primary cytomegalovirus (CMV) infection and its consequences for the offspring. In the high-income group, 64.5% of the women were seronegative for CMV and 1.6% had primary CMV infection. In the low-income group, only 23.4% of the women were seronegative for CMV, but 3.7% experienced a primary infection. The rate of transmission in utero was similar in the two groups (39% and 31%). Congenital infections were more frequent in the low-income group; however, primary CMV accounted for 25% of the congenital infections in this group, in contrast to 63% of the high-income cases. Infections acquired early and late in gestation had similar rates of transmission in utero, but three infants (8%) with symptomatic congenital infection and five infants (13.5%) who have developed significant handicaps were exposed in the first half of pregnancy. Primary CMV infection during pregnancy poses a 30% to 40% risk of intrauterine transmission and adverse outcome is more likely when infection occurs within the first half of gestation. (<i>JAMA</i>1986;256:1904-1908)
Trends in postneonatal mortality in the United States. 1962 through 1978
Authors: M. J. Khoury
Journal: JAMA (1984)

Trends in postneonatal mortality (PNM) rates in the United States were analyzed for the period 1962 through 1978 using National Center for Health Statistics birth and death certificate data. The PNM rates declined from 5.5 to 3.6 per 1,000 live births for whites and from 15.6 to 7.6 per 1,000 live births for blacks. Most of the decline in PNM rates could be accounted for by a drop in mortality from infectious diseases. A dramatic increase occurred in the reported rates of unexplained sudden infant death (SID), which emerged as the leading reported cause of PNM. The second leading cause of PNM was birth defects among whites and infectious diseases among blacks. Gaps in PNM continued to exist between whites and blacks, and between metropolitan and nonmetropolitan areas. These gaps suggest that further improvement in PNM may be possible by improving access to health care. The massive increase in the rates of SID, although partially explained by coding or reporting phenomena, warrants active pursuit for a better pathophysiologic and etiologic delineation of the entity. (<i>JAMA</i>1984;252:367-372)
Hospital, high schools span 'age gap'
Authors: P. Gunby
Journal: JAMA (1979)

Hospitals and high schools usually have little in common. But the Sepulveda, Calif, Veterans Administration Hospital and three nearby high schools have a good thing going. What it amounts to, said Howard F. Wallach, MD, at the recent Gerontological Society meeting in Dallas, is a spanning of at least one generation gap by bringing young visitors to the chronic care area. The mean age of the patients in the hospital's Nursing Home Care Unit is 68 years. The youngsters who come to visit them are in their midteens. Wallach, who heads the Division of Geropsychiatry at the hospital, started the project four years ago with ten students from nearby Monroe High School and ten men who were patients in the chronic care unit. Now, he says, 80 students from three high schools participate each semester, visiting at least 80 patients. The students receive school credit for their efforts, and so
Necrotic Arachnidism—Pacific Northwest, 1988-1996
Journal: JAMA (1996)

Although spider bites are common in many parts of the United States, most domestic spiders are not substantially venomous to man. The best known exceptions are widow spiders (Latrodectus spp., including the black widow L. mactans) and brown spiders (Loxesceles spp., particularly the brown recluse, Lox. reclusa). However, cases of arachnid envenomation from the hobo spider (Tegenaria agrestis) are being reported increasingly in the Pacific Northwest. This report summarizes investigations of three cases of T. agrestis bites among persons in Idaho, Oregon, and Washington; spider bites reported to U.S. poison-control centers during 1994; and emphasizes the need for physicians in the northwestern United States to consider the species as a cause of toxic arachnidism.
Satellite Broadcast on HIV Prevention
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Randomized trial comparing three different regimens of interferon alfa 2a in chronic hepatitis C
Authors: M Angelico
Journal: Hepatology (1996)

small numbers of HCC cells may be released into the man research review committee.Informed consent had been obtained from the patients involved.circulation, be it spontaneously or induced by surgicalThe results show that albumin mRNA can be demanipulation.Based on their findings, the authors sugtected in central as well as peripheral blood samples gest that, indeed, circulating tumor cells are present collected after, but not before, recipient hepatectomy.in the peripheral circulation as indicated by the PCR A semiquantitive analysis, as expressed by log mRNA technique.equivalents per milliliter of blood, reveals identical We believe that the outcome of their experiments amounts of albumin expression in blood samples colshould be interpreted more cautiously.As mentioned lected at the indicated time points within the first 24 by Carr in an editorial on this subject in 1994, the hours.Because histological examination of the hepatecassay does not actually measure cancer cells. 2 Thus, tomized livers confirmed the absence of any maligthe mRNA-PCR technique identifies a liver-specific cell nancy, we conclude that positive results of an albumin marker that also may indicate the presence of nontu-mRNA test as such has no predictive value for the presmoral hepatic cells in the circulation.However, because ence of HCC.It may well be that hepatocytes, which the authors only found a positive PCR signal for albuare released into the circulation by surgical manipulamin mRNA in isolated cells from the peripheral blood tion or by reperfusion, are the origin of the albumin of patients with advanced-stage HCC, they speculated mRNA.that it was a result of the presence of malignant cells.Our findings of positive results of an albumin mRNA The authors did not mention the time points at which assay in patients without a malignancy are in accorblood samples were obtained.The results of our studies dance with the report or Matsumura et al., 3 who using the same technique to detect albumin mRNA showed the presence of albumin mRNA in peripheral within the first 24 hours after liver transplantation blood of normal volunteers.Their results and those of show different results and cast doubt on the value of our study indicate that the consequences of positive this assay as a method to identify the presence of maligassay results for albumin mRNA should be interpreted nant cells in the circulation after liver transplantation.cautiously in relation to HCC.We have conducted a study in which peripheral and central whole blood samples were taken at regular in-JAN N. M. IJZERMANS 1 tervals (immediately before surgery and 5, 30, 60, and DIRK-JAN BAC 2 120 minutes and 24 hours after recipient hepatectomy) BERT G. M. NIESTERS 3 from five consecutive patients undergoing liver trans-Departments of 1 Surgery, 2 Hepatology, and plantation for benign liver disease.Indications for liver
Homelessness
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Corrigendum
Journal: BMJ (1937)

shown in his 1936-7 return to the dividends, etc., of himself and his wife shown in the 1937-8 return.Is that correct?*** Yes.The basis on which surtax is chargeable is laid down in Section 38 of the Finance Act, 1927, and in effect is the income of the actual year of assessment.The assessment referred to by -"Super" is for the financial year 1936-7, and as the ordina-ry income tax is assessed on the basis of the previous year's earnings the amount he entered in his income tax declaration for 1937-8 would be the statutory income of the year 1936-7.The personal allowance, whether for a single or a married man, applies only to " standard-rate" tax and not to surtax.
Diagnostic Laparoscopy: An Update
Authors: K. Saeian, K. R. Reddy
Journal: Endoscopy (1999)

With new technical advances, wider availability, and the recent proliferation of less invasive surgery, the use of diagnostic laparoscopy has expanded far beyond its traditional role in the evaluation of chronic liver disease. Short of open laparotomy, diagnostic laparoscopy is the most accurate modality for staging of intra-abdominal malignancies, and is particularly well-suited for patients who otherwise would not require surgical palliation. In addition to avoiding unnecessary laparotomy in this group, diagnostic laparoscopy has proved valuable in the assessment of abdominal trauma, acute abdomen, and ischemic bowel disease. We briefly review here some of the new developments in the field of diagnostic laparoscopy.
Baby Stealing
Authors: P. T. D'Orban
Journal: BMJ (1972)

Analysis of 13 cases of baby stealing by women distinguished four groups of cases. (1) Girls of subnormal intelligence, who stole a baby to play with. (2) Schizophrenic patients, whose offence was motivated by delusional ideas. (3) Psychopathic personalities, characterized by a previous history of delinquency, hysterical personality traits, and a preoccupation with their desire to have children. Their baby stealing seemed motivated by an attempt to compensate for their emotional deprivation, and they usually stole children whom they had previously helped to care for. (4) A "manipulative" group with a milder degree of personality disorder, in whom the motive for baby stealing was an attempt to influence a man by whom they had become pregnant and with whom their relationship was insecure. The offence was precipitated by a crisis such as a miscarriage or the threat of desertion. These women presented the stolen baby to their partner pretending that the child was his.Baby stealing seems usually to be an attempt to compensate for emotional deprivation or frustrated maternal feelings, and a real or imaginary miscarriage may be a predisposing or precipitating factor. The offence rarely seems premediated, though there was evidence of previous planning in some cases, particularly in the manipulative group. The stolen babies were well cared for and were usually quickly recovered.
Le Gonocoque.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Status asthmaticus and pancuronium bromide
Authors: N. Levin
Journal: JAMA (1972)

The use of neuromuscular blocking agents as an adjunct to accepted drug therapy in medically irreversible status asthmaticus allows time for the drug therapy to become effective. The accessory muscles of respiration are also relaxed and, therefore, a decrease in oxygen demand by the body occurs. Four cases of medically irreversible status asthmaticus occurred in which pancuronium bromide, a new nondepolarizing neuromuscular blocking agent was used. The advantages of pancuronium bromide over the other nondepolarizing agents are that it does not cause histamine release and has no significant cardiovascular effects.