tbuckley/cabot-search huggingface dataset:
Randomised controlled trial to compare surgical stabilisation of the lumbar spine with an intensive rehabilitation programme for patients with chronic low back pain: the MRC spine stabilisation trial
Journal: BMJ (2005)

menopausal soon after hysterectomy.We were therefore unable to carry out separate analyses using menopausal status.Previous studies have looked at risk of specific cancers after hysterectomy, rather than all cancer mortality.The reduced risk of ovarian cancer after hysterectomy found in one study 19 may have been due to a screening effect, as surgery provides an opportunity to detect abnormal ovaries.Such effects would persist for as long as it takes visible premalignant abnormalities to produce symptoms of cancer. 19This bias could have occurred in our study, although it is not clear how long such a protective effect might have influenced our risk estimates of all cancer mortality.Most women in our study had a hysterectomy for non-malignant reasons.They would no longer be at risk of endometrial, cervical, or ovarian cancer if they also had bilateral oophorectomy.Cancers comprise more than a third of deaths in middle aged women, with many at gynaecological sites.The observed lower risk of death (although not statistically significant) from all causes and from cancer among young women who had a hysterectomy was therefore unsurprising.Our results ignore any non-fatal, physical, psychological, and social costs to the individual after hysterectomy.The results should therefore not be used to argue that hysterectomy be used as a public health measure to reduce women's risk of death later in life.Instead, patients should be reassured that hysterectomy will not put their lives at risk later on.
Energy crisis
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nutrition Recommendations and Principles for People With Diabetes Mellitus
Journal: Diabetes Care (1994)

A historical perspective of nutrition recommendations is provided in Table 1. Today there is no ONE "diabetic" or "ADA" diet. The recommended diet can only be defined as a dietary prescription based on nutrition assessment and treatment goals. Medical nutrition therapy for people with diabetes should be individualized, with consideration given to usual eating habits and other lifestyle factors. Nutrition recommendations are then developed to meet treatment goals and desired outcomes. Monitoring metabolic parameters including blood glucose, glycated hemoglobin, lipids, blood pressure, and body weight, as well as quality of life, is crucial to ensure successful outcomes.
Non-specificity of surfactant deficiency in neonatal respiratory disorders
Authors: P A Jenkins, W O T. Mordi, J D Baum
Journal: BMJ (1984)

1383 portion of HbA, was high in carriers and nor- mal in controls.HbF determined by cellogel electrophoresis was present in three carriers.HbA, was measured by a column chromato- graphic method6 in blood samples drawn after about 12 hours' fasting and immediately tested at 23-C.The HbAj concentration in carriers of 5 thalassaemia trait was higher than that in controls (9-3 (SD 1-7)')0 v 7 1 (0 8)o; t test for unpaired data: p<0 001).This difference remained significant even when carriers with HbF were excluded from the comparison.We found no direct relation between HbA2and HbAj.The cause of our results remains a matter of speculation.Nevertheless, we think it is im- portant to be aware that the usual column chromatographic method of measuring HbAj might give high results in carriers of P thalas- saemia trait.
Zh Mikrobiol, Epidem i Immunobiol, Moscow
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hyperbilirubinemia of fasting
Authors: P. V. Barrett
Journal: JAMA (1971)

The effect of a 44- to 48-hour fast on the serum bilirubin concentration was studied in five normal subjects and in five patients with hepatic dysfunction. The total serum bilirubin (TSB) concentration increased progressively during the fasting period in all patients; expressed as a percent of the control value, it averaged 240% for the normal subjects and 194% for the patients with hepatic dysfunction at the completion of the fast (<i>P</i>&gt;0.05). One normal subject fasted for 110 hours; the TSB increased to 326% of the control value at 63 hours and then fell to approximately twice the control value for the remainder of the fast. A diurnal rhythm of the TSB was demonstrated in one patient, but was suppressed by nocturnal feedings. It was concluded that an increase in bilirubin concentration occurs as a function of fasting.
Registry for sarcoid heart disease
Authors: E. L. Kinney
Journal: JAMA (1979)

<h3>In Reply.—</h3> All of the cases in our retrospective study were chosen because they had clinical sore throat and cultures of the posterior pharynx that were positive for group A β-hemolytic<i>Streptococcus</i>; ASO titers were not obtained. Although we agree with Bisno<sup>1</sup>that the throat culture is the most effective test for differentiating streptococcal from nonstreptococcal sore throat, it is possible that some of our patients had viral sore throat with streptococcal colonization. The purpose of our study was to ascertain if the time of administration of penicillin could be shown to have an effect on the duration of the clinical illness seen in our hospital. It could not. Dr Weissbluth is correct: ours was a retrospective study. However, if no effect is shown, it seems unnecessary to use placebo controls. We are in full agreement with Komaroff's<sup>2</sup>strategy for immediate treatment.
Resident Burnout
Authors: Anthony L. Back, Joyce E. Wipf, Tait D. Shanafelt
Journal: Annals of Internal Medicine (2002)

Letters15 October 2002Resident BurnoutAnthony L. Back, MD, Joyce E. Wipf, MD, and Tait D. Shanafelt, MDAnthony L. Back, MDUniversity of Washington; Seattle, WA 98108Mayo Clinic; Rochester, MN 55905Search for more papers by this author, Joyce E. Wipf, MDUniversity of Washington; Seattle, WA 98108Mayo Clinic; Rochester, MN 55905Search for more papers by this author, and Tait D. Shanafelt, MDUniversity of Washington; Seattle, WA 98108Mayo Clinic; Rochester, MN 55905Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-8-200210150-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We appreciate the interest in our study of burnout in residents. Dr. Nash points out the need for caution in altering residency training and notes the lack of empirical evidence on which changes could be based. We agree that evidence is scant and view our study as an early step in establishing such an evidence base. Drs. Beckman and Fang speculate that our results disproportionately reflect a disaffected group of residents. This seems unlikely to us, since more than three quarters of the residents in the study met criteria for burnout and the participation rate was 76%. Dr. ...References1. Csikszentmihalyi M. Flow: The Psychology of Optimal Experience. New York: HarperCollins; 1991. Google Scholar2. Epstein RM, Hundert EM. Defining and assessing professional competence. JAMA. 2002;287:226-35. [PMID: 11779266] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: University of Washington; Seattle, WA 98108Mayo Clinic; Rochester, MN 55905 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBurnout and Self-Reported Patient Care in an Internal Medicine Residency Program Tait D. Shanafelt , Katharine A. Bradley , Joyce E. Wipf , and Anthony L. Back Resident Burnout Ira S. Nash Resident Burnout W. Robert Graham Resident Burnout Troy Madsen Metrics Cited By Burnout in Healthcare Workers: Prevalence, Impact and Preventative Strategies The well-being of physicians 15 October 2002Volume 137, Issue 8Page: 700KeywordsAcademic medicinePsychologyResidency ePublished: 15 October 2002 Issue Published: 15 October 2002 CopyrightCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Treatment of Acute Lymphoblastic Leukaemia: Effect of "Prophylactic" Radiotherapy against Central Nervous System Leukaemia: REPORT TO THE MEDICAL RESEARCH COUNCIL BY THE LEUKAEMIA COMMITTEE AND THE WORKING PARTY ON LEUKAEMIA IN CHILDHOOD
Authors: J Hutchison, R Hardisty, K Bagshawe, J Bridges, N Butler, P Deasy, D Evans, D Galton, R Guyer, F Harris, C Howarth, E Innes, H Jones, P Jones, H Kay, I Maclennan, D Mainwaring, J Martin, M Philpott, M Pike, J Stuart, E Thompson, M Till, M Willoughby
Journal: BMJ (1973)

A total of 177 patients with acute lymphoblastic leukaemia aged 1 to 13 years were entered in a trial in which one of the variables was “prophylactic” treatment against central nervous system (C.N.S.) relapse. Patients who achieved haematological remission on a standard chemotherapy regimen either received or did not receive craniospinal irradiation plus intrathecal methotrexate. Of the 80 patients who did not receive prophylactic C.N.S. treatment remission was terminated by meningeal leukaemia in 26. The corresponding figure for patients given prophylactic C.N.S. treatment was only 1 out of 75. The incidence of marrow relapse, however, is so far similar in the two groups. If the occurrence of either meningeal leukaemia or marrow relapse is taken to indicate recurrence of leukaemia then 32 out of 80 patients receiving no C.N.S. prophylaxis have so far relapsed compared with 14 out of 75 patients who received C.N.S. prophylaxis. This represents a halving of the recurrence rate in the prophylactic group: it is estimated that 75% of this group will remain free of either form of recurrence for 71 weeks after radiation treatment.
Very High Doses of Methadone May Cause Abnormal Heart Rhythm
Journal: Annals of Internal Medicine (2002)

Summaries for Patients17 September 2002Very High Doses of Methadone May Cause Abnormal Heart RhythmAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-6-200209170-00004 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?At rest, the heart usually pumps blood at a rate of 60 to 90 beats per minute. Although extra beats occasionally occur, the normal pattern (rhythm) of heartbeats is fairly regular. The heart has an electrical system that runs through the upper heart chambers (atria) and the lower heart chambers (ventricles). The electrical system controls the heart rate and rhythm. Age, diseases, and drugs can affect the electrical system and cause abnormal rhythms (arrhythmia). Some arrhythmias reduce the ability of the heart to pump blood. Some even cause ... Author, Article, and Disclosure InformationThe summary below is from the full report titled "Torsade de Pointes Associated with Very-High-Dose Methadone." It is in the 17 September 2002 issue of Annals of Internal Medicine (volume 137, pages 501-504). The authors are MJ Krantz, L Lewkowiez, H Hays, MA Woodroffe, AD Robertson, and PS Mehler.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoTorsade de Pointes Associated with Very-High-Dose Methadone Mori J. Krantz , Laurent Lewkowiez , Helen Hays , Mary Ann Woodroffe , Alastair D. Robertson , and Philip S. Mehler Metrics 17 September 2002Volume 137, Issue 6Page: I-42KeywordsArrhythmiaBloodDrug addictionDrug therapyDrugsHeartHeart ratePacemakersPotassiumShock ePublished: 17 September 2002 Issue Published: 17 September 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
THE AMERICAN FEDERATION FOR CLINICAL RESEARCH TWENTY-SECOND ANNUAL MEETING
Authors: Morton Bogdonoff, P Vassalli, R Mccluskey, G Gallo, D Baldwin, New York, Uremia Slatopolsky, L Gradowska, C Kashemsant, R Keltner, C Manley, N Bricker, St Louis, Fraction Beall, D Solomon, Thomas Fitzpatrick
Journal: Journal of Clinical Investigation (1965)
THE PILL'S GRIM (?) PROGRESS
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Immunity Against Zymotic Diseases.
Authors: W. J. Class
Journal: JAMA (1901)

Chicago, April 28, 1901. <h3>To the Editor:</h3> —InThe Journalof April 27 there appeared a letter by Dr. Corban E. Judd, relating to an article recently published by me in which I had formulated a theory in regard to acquired immunity. Dr. Judd states that Dr. O. P. Davis, of Topeka, Kan., had presented a paper before the Medical Science Club of Topeka, on Feb. 18, 1901, which, to use Dr. Judd's words, "embraced all that Dr. Class sets forth and more." As my paper was published April 13, 1901, a claim for priority is made in favor of Dr. Davis. Priority squabbles are usually not very edifying, and in this case of no particular moment; still, I would like to state my position. Dr. Judd states that Dr. Davis's theory embraced all that I set forth and more. Dr. Davis, by saying "more," made his theory different from
Women who smoke have a greater risk of myocardial infarction than men who smoke
Journal: BMJ (1998)

Women who smoke have a greater risk of myocardial infarction than men who smoke Studies of smoking and cardiovascular disease may have underestimated the risk in women because until recently women's smoking habits have differed greatly from men's.During the past few decades, however, women have taken up smoking like men.Using data from three large prospective studies in Copenhagen that included many women who were heavy smokers, Prescott et al (p 1043) found that the smoking related risk of myocardial infarction was 50% higher in women than in men.This difference may be caused by interactions between components of tobacco smoke and hormonal factors.
Psychiatry
Authors: John C. Markowitz
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
'Statins' May Offer Extra Insurance
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Severe neurological sequelae after liver transplantation for fulminant hepatitis: Role of the pretransplant condition Ph. Ichai, Ph. Chemouilly, F. Saliba, D. Azoulay, H. Bismuth. Hepatobiliary Surgery and Liver Transplantation Center, Paul Brousse Hospital, 94800 Villejuif, France
Journal: Hepatology (1995)
Consensus conference. Newborn screening for sickle cell disease and other hemoglobinopathies
Journal: JAMA (1987)

Sickle cell anemia and other hemoglobinopathies represent a major health problem in the United States. In April 1987 several federal agencies sponsored a National Institutes of Health Consensus Development Conference to discuss the issues involved in diagnosing and treating some of the major hemoglobinopathies in infants. This report summarizes the consensus panel's answers to the following questions considered by the conference participants: 1) are newborn screening programs for sickle cell anemia effective in reducing morbidity and mortality?, 2) what are the current screening techniques and their efficacies?, 3) what are the risk/benefit considerations in newborn screening programs?, 4) once infants with hemoglobinopathies have been identified, what are the optimal follow-up and management strategies?, and 5) what directions should research follow?
Rituximab Maintenance In Patients with Chronic Lymphocytic Leukemia (CLL) After Upfront Treatment with Rituximab Plus Fludarabine, Cyclophosphamide, and Mitoxantrone (R-FCM): Final Results of a Multicenter Phase II Trial On Behalf of the Spanish CLL Study Group (GELLC)
Authors: Francesc Bosch, Pau Abrisqueta, Neus Villamor, María José Terol, Eva González-Barca, Marcos González, Christelle Ferrà, Eugenia Abella, Julio Delgado, Jose A. Garcia-Marco, Yolanda Gonzalez, Felix Carbonell, Secundino Ferrer, Encarna Monzo, Isidro Jarque, Ana Muntanola, Mireia Constants, Lourdes Escoda, Emili Montserrat
Journal: Blood (2011)
Tetracycline-Reply
Authors: B. H. KEAN
Journal: JAMA (1976)

Tetracycline remains a useful drug in the treatment of amebiasis, but paromomycin sulfate is more effective gram for gram. Few patients whom my colleagues and I have treated with two grams of tetracycline daily for various diseases could tolerate the program for more than a week. Perhaps patients receiving high doses of tetracycline do not complain about their diarrhea to their dermatologists, but rather to their internists.
AIDS, zinc deficiency, and thymic hormone failure
Authors: N. Fabris
Journal: JAMA (1988)

<h3>To the Editor.</h3> —It has been proposed that thymic secretory function, as assessed by determining levels of circulating thymulin—like activity,<sup>1</sup>is greatly reduced in patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex.<sup>2,3</sup>In fact, in both young<sup>3</sup>and adult<sup>2</sup>patients, levels of circulating thymulin, as measured by the rosette inhibition bioassay, are either undetectable or below the values found in age-matched healthy subjects. These findings have been interpreted as showing human immunodeficiency virus (HIV)—induced injury of the thymic epithelial cells that synthesize and release thymic hormones.<sup>4</sup> Since thymulin is biologically active, and therefore measurable by bioassay only when the nonapeptide thymulin is bound to a zinc ion,<sup>5</sup>a reduced circulating level may depend not only on defective production by the thymus, but also on decreased zinc binding, as might occur in zinc deficiencies.<sup>6</sup>In these conditions, inactive, zinc—unbound thymulin molecules are found