tbuckley/cabot-search huggingface dataset:
EXPERIMENTAL NEUTRALIZATION OF REDUCED RESISTANCE TO CANCER CELLS AFTER OPERATIVE STRESS
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A legislative look at heroin and medicine
Authors: B. J. Montgomery
Journal: JAMA (1978)

The political and emotional fervor surrounding the question of the medical usage of heroin is growing considerably, though it may not yet rival the laetrile issue. Even generally conservative medical societies are publically voicing their approval and disapproval of efforts to make heroin medically available in the near future. The 15,000-member American Society of Internal Medicine has endorsed the idea of making heroin available in specific cases. Last June the American Medical Association's House of Delegates took the opposite position and refused to make such an endorsement because those voting believed that there should be more investigational data first. The American Cancer Society has more or less straddled the fence. Its Board of Directors made a statement in February that declared in part: "Pain is a major health problem in this country, especially the kind of pain that is sometimes encountered in patients with cancer. According to experts the treatment
<i>The Diseases of the Nervous System.</i>A Text-Book for Physicians and Students. By Dr. Ludwig Hirt, Professor at the University of Breslau. Translated, with permission of the author, by August Hoch, M. D., formerly Assistant Physician to the Johns Hopkins Hospital, now to the McLean Hospital, Waverley, Mass., assisted by Frank R. Smith, A. M., M. D., Instructor in Medicine in the Johns Hopkins University. With an introduction by William Osler, M. D., F. R. C. P., F. R. S., Professor of …
Journal: American Journal of Psychiatry (1899)
AMA-RPS annual meeting actions
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Observations on Typhoid or Intestinal Fever: The Pythogenic Theory
Authors: W. Budd
Journal: BMJ (1861)

So the ordinary face and view of experience is many times satisfied by several theories and philosophies; whereas, to find the real truth, requireth another manner of severity and attention." (Advancement of Learning.)PART I. Pytthogenic Theory Irreconcilable with the Prolonged Absence of Typhoid Fever in Villages where Pytho- genic Comnpou0nds are rife; also, with the Low State of Fever-Sickness and Mlortality in the Population exposed to the Foul Sewaaqe Emanations of the Thames in 1858-.59.The Phenomena really those of a Contagiouts Fever dissenminated (chiefly) byLiquid Discharges.IN studying the march of scientific discovery, there are few lessons more strongly impressed upon us than this: that a theory which merely embodies an inference drawn from a single order of facts is, for that reason, almost sure to be wrong, however clear and inevitable the inference itself may at first sight seem to be.
Angiosarcoma of the liver in a rural population. Four cases diagnosed in a 29-month period
Authors: J. J. Fiechtner
Journal: JAMA (1976)

Angiosarcoma of the liver has recently been publicized because of its association with polyvinyl chloride (PVC) polymerization workers. Four cases of this rare tumor have been observed at the Marshfield Clinic within a 29-month period. There are no factories that manufacture PVC products in the immediate area, nor were any of the victims ever involved in such manufacturing work. Thus, it is possible that other factors may be related to this cluster of the disease. (<i>JAMA</i>236:1704-1706, 1976)
Respiratory symptoms, asthma, exercise test spirometry, and atopy in schoolchildren from a Lima shanty town
Authors: M E Penny, S Murad, S S Madrid, T S Herrera, A Piñeiro, D E Caceres, C F Lanata
Journal: Thorax (2001)

BACKGROUND Little is known about the associations between symptoms of asthma, pulmonary function tests, and atopy in developing countries. While asthma in children is often associated with atopy, some studies of wheezing illness have found little or no association, leading to suggestions that there are subgroups of wheezing illness. The ISAAC study recently reported that the prevalence of reported asthma symptoms in Lima, Peru was among the highest in the world, but did not report on the atopic status of the subjects. METHODS A cross sectional survey was conducted of children aged 8–10 years who had previously participated in a cohort study of respiratory and diarrhoeal illnesses in infancy. Questionnaires were administered asking about respiratory symptoms and asthma diagnoses, pulmonary function tests were performed before and after exercise on a treadmill, and atopy was determined from skin prick tests and specific serum IgE levels. RESULTS A total of 793 children participated in the survey. The prevalence of asthma related symptoms in the last 12 months was 23.2%, but only 3.8% of children reported a recent asthma attack. The mean differences in pretest percentage predicted forced expiratory volume in one second (FEV 1 ) were 8.1% (95% CI 2.4 to 13.8) between children who did and did not report an asthma attack in the last 12 months, and 5.3% (95% CI 2.8 to 7.9) in children who did and did not report respiratory symptoms. The corresponding differences in mean percentage fall in FEV 1 after exercise were 3.1% (95% CI –1 to 7.1) and 5.1% (95% CI 3.4 to 6.8). Recent asthma or respiratory symptoms were not associated with atopy in this population (odds ratios 1.29 (95% CI 0.56 to 2.97) and 0.91 (95% CI 0.61 to 1.37), respectively). CONCLUSIONS Most asthma in these children was unrecognised and mild. Asthma and asthma symptoms in this population do not seem to be related to atopy.
International consensus report urges sweeping reform in asthma treatment
Authors: T. Randall
Journal: JAMA (1992)

AN INTERNATIONAL panel of asthma experts is advising physicians to adopt a sweeping philosophical change in the way they manage asthma. Treat asthma not as an episodic, bronchospastic disorder, they suggest, but as a chronic, persistent disease with inflammation at its core. That is the word from the International Asthma Management Project, a working group of 18 physicians and scientists convened by the National Heart, Lung, and Blood Institute, Bethesda, Md, in their now-released report on the diagnosis and management of asthma. In what is termed an international consensus, the report recommends regular use of anti-inflammatory drugs, preferably inhaled corticosteroids, as first-line therapy for anything more than occasional mild asthma. β<sub>2</sub>-Agonist bronchodilators, commonly used in the United States as regularly scheduled, first-line therapy, are endorsed only for the pretreatment of exercise-induced asthma and for the symptomatic relief of acute exacerbations, or "asthma attacks," when anti-inflammatory therapy is insufficient.
Perihepatitis associated with salpingitis in adolescents
Authors: I. F. Litt
Journal: JAMA (1978)

Perihepatitis, one manifestation of complicated gonorrhea, is infrequently diagnosed and reported. This study was undertaken to examine the incidence of gonococcal perihepatitis in adolescents as well as to study the effect, if any, of this condition on tests of liver function. Accordingly, the records of 137 adolescents with salpingitis were evaluated. Right upper quadrant tenderness or hepatic enlargement was noted in 27, while amino transferase level elevations were observed in 19 of the 59 in whom these tests were performed. All findings resolved promptly following initiation of intravenous penicillin therapy. The observation of hepatic dysfunction in 27% of these adolescents suggests that perihepatitis occurs more frequently than reported in adults and should be considered in the evaluation of the conditions of adolescents with salpingitis or upper abdominal tenderness. (<i>JAMA</i>240:1253-1254, 1978)
SHOULD SYPHILITIC MEDICAL MEN CONTINUE IN PRACTICE?
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 16819: Sequencing of Genetic Loci Associated With Leukocyte Telomere Length Reveals New Intronic Variants in African Americans
Authors: Rasika Mathias, Kruthika Iyer, Margaret Taub, Lisa Yanek, Diane Becker, Lewis Becker, Dhananjay Vaidya
Journal: Circulation (2015)

Background: Shorter telomere length is associated with an increased risk of coronary artery disease (CAD). A prior genomewide association study (GWAS) on 37,684 European ancestry individuals identified seven loci determining leukocyte telomere length (LTL). A genetic risk score across all 7 loci showed an association with CAD. In this study we sequenced these loci to determine whether the same risk variants could be replicated in African admixed individuals. Methods: We used whole genome sequence data (WGS) in 127 healthy African American subjects from GeneSTAR, a family study of early-onset CAD. LTL was calculated from WGS raw bam data (&gt;30x coverage on the Illumina HiSeq platform) for 7 contiguous repeats of the telomere motif (TTAGGG or CCCTAA, Ding et al., 2014). Tests for association for LTL adjusting for age and sex were performed for a total of 55,821 called variants from ~1Mb subset regions of WGS genotype data centered on each of the 7 European peak GWAS SNPs. Results: We identified a total of 17 variants with p&lt;5x10 -4 mapping to 6 of the 7 regions examined; none of the prior European GWAS peak SNPs were significant. The peak SNP per region in the African Americans included intronic variants rs77138331 in ACYP2 (p=0.0005, MAF = 7%), rs149577640 in NAF1 (p=0.002, MAF=1%), rs35387865 in TERT (p=0.003, MAF = 1%) and rs186486116 in OBFC1 (p=0.004, MAF=1%). Additionally, novel intronic variants not previously observed in dbSNP located at chr19: 22190184 (p=0.005, MAF=1%) and chr2:62445438 (0.005, MAF=2%), mapping to ZNF208 and RTEL1 , were also identified as determinants of LTL. Discussion: This is the first study of telomere length in African Americans using a sequencing approach. We are unable to confirm the European-based GWAS variants but identify several associations mapping to genes of importance in telomere biology. Our results provide evidence that the set of SNPs to be included in calculation of a telomeric genetic CAD risk score may be different in populations of European and African ancestry.
Satisfactory remission in a case of IgD myeloma: Effectiveness of glucocorticoid treatment
Authors: Nobuo Takemori, Keiichi Kondo, Takahito Kawamura, Kiyotoshi Imai, Hiroharu Sakurai, Teiko Sato
Journal: American Journal of Hematology (2001)

IgD myeloma is an infrequent type of multiple myeloma and is characterized by an aggressive clinical behavior and a short survival time. No satisfactory treatments have thus far been established. Recently we treated a patient with IgD(λ)-type myeloma with glucocorticoids, and succeeded in achieving a complete remission. This case seems to indicate a usefulness of glucocorticoid monotherapy for treating IgD myeloma. Am. J. Hematol. 66:62–63, 2001. © 2001 Wiley-Liss, Inc.
MEDICAL AND SPIRITUAL CO-OPERATION IN RELIGIONEUROTIC CASES.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Managing passengers with stable respiratory disease planning air travel: British Thoracic Society recommendations
Authors: S. Ahmedzai, I. M. Balfour-Lynn, T. Bewick, R. Buchdahl, R. K. Coker, A. R. Cummin, D. P. Gradwell, L. Howard, J. A. Innes, A. O. C. Johnson, E. Lim, W. S. Lim, K. P. McKinlay, M. R. Partridge, M. Popplestone, A. Pozniak, A. Robson, C. L. Shovlin, D. Shrikrishna, A. Simonds, P. Tait, M. Thomas
Journal: Thorax (2011)

is possible because of proximity to others with contagious diseases (ie, resulting from direct person-to-person transmission).
Rituximab-PECC Induction Followed by 90y-Ibritumomab Tiuxetan Consolidation in Relapsed or Refractory DLBCL Patients Who Are Not Eligible for or After ASCT: Preliminary Results From a Phase II HOVON Study.
Authors: Pieternella J Lugtenburg, Josée M Zijlstra, Jeanette K Doorduijn, Lara H Böhmer, Marinus van Marwijk Kooy, Mels Hoogendoorn, Henriette W Berenschot, Aart Beeker, Fransje A Valster, Harry C Schouten, Marleen Luten, Dana A Chitu, Rolf E Brouwer, Gustaaf W van Imhoff
Journal: Blood (2012)
Comparative Toxicity of PCBs and Related Compounds in Various Species of Animals
Authors: Ernest E. McConnell
Journal: Environmental Health Perspectives (1985)

There are several basic principles that apply to the clinicopathologic syndrome produced by polychlorinated biphenyls (PCBs). They are as follows: The degree of halogenation and position of the halogen atoms determine the potency of PCB, PBB, CDD, CDF and CN; in a given species of animals, the clinicopathologic syndrome induced by PCB is comparable to that induced by polybrominated biphenyls (PBB), chlorinated dibenzo-p-dioxins (CDD), chlorinated dibenzofurans (CDF), and chlorinated naphthalenes (CN) when an equitoxic dose is achieved; The clinicopathologic syndrome is different in each species of animals; Different species of animals vary in their susceptibility to intoxication; intoxication is more readily effected in young animals that in adults; at lethal doses the time between exposure and death is prolonged (greater than 2 weeks).
Late Sequelae of Induced Abortion
Authors: Nathan Hoeldtke
Journal: Annals of Internal Medicine (2004)

Letters20 July 2004Late Sequelae of Induced AbortionNathan Hoeldtke, MDNathan Hoeldtke, MDFrom Honolulu, HI 96859.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-141-2-200407200-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:I was surprised to read the review of induced abortion by Grimes and Creinin (1). Several years ago, Dr. Grimes stated, “Traditional review articles are not just obsolete; they also are nonreproducible and of low scientific quality … [O]ne analysis … found a significant inverse relationship between adherence to scientific standards for a literature review and the self-professed expertise of an author” (2). Indeed, Grimes and Creinin's current review seems to bear this out, being crippled by selective literature citation and hyperbole.Grimes and Creinin stated that abortion has no effect on future reproductive function and cited ...References1. Grimes DA, Creinin MD. Induced abortion: an overview for internists. Ann Intern Med. 2004;140:620-6. [PMID: 15096333] LinkGoogle Scholar2. Grimes DA. Evidence-based medicine: keeping your practice from getting stale. Contemporary OB/GYN. 1999;Jan:41-54. Google Scholar3. Thorp JM, Hartmann KE, Shadigian E. Long-term physical and psychological health consequences of induced abortion: review of the evidence. Obstet Gynecol Surv. 2003;58:67-79. [PMID: 12544786] CrossrefMedlineGoogle Scholar4. Gissler M, Hemminki E, Lonnqvist J. Suicides after pregnancy in Finland, 1987-94: register linkage study. BMJ. 1996;313:1431-4. [PMID: 8973229] CrossrefMedlineGoogle Scholar5. Reardon DC, Ney PG, Scheuren F, Cougle J, Coleman PK, Strahan TW. Deaths associated with pregnancy outcome: a record linkage study of low income women. South Med J. 2002;95:834-41. [PMID: 12190217] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Nathan Hoeldtke, MDAffiliations: From Honolulu, HI 96859. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoInduced Abortion: An Overview for Internists David A. Grimes and Mitchell D. Creinin Late Sequelae of Induced Abortion William J. Stone Late Sequelae of Induced Abortion David A. Grimes and Mitchell D. Creinin Metrics 20 July 2004Volume 141, Issue 2Page: 161KeywordsExerciseForecastingMedical conditionsMedical risk factorsPatientsPregnancySuicide ePublished: 20 July 2004 Issue Published: 20 July 2004 Copyright & PermissionsCopyright © 2004 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Optimal time-point of response assessment for predicting survival is associated with tumor burden in hepatocellular carcinoma receiving repeated transarterial chemoembolization
Authors: Dongdong Xia, Qiuhe Wang, Enxin Wang, Wei Bai, Zhexuan Wang, Wei Mu, Junhui Sun, Ming Huang, Guowen Yin, Hailiang Li, Hui Zhao, Chunqing Zhang, Jing Li, Jianbing Wu, Xiaoli Zhu, Shufa Yang, Xingnan Pan, Jiaping Li, Zixiang Li, Guohui Xu, Haibin Shi, Wenjun Wang, Jing Niu, Zhanxin Yin, Jielai Xia, Guohong Han
Journal: Journal of Hepatology (2020)
Simultaneous drug reactions in the same patient. Chloroquine-Primaquine sensitivity
Authors: D. D. Stevenson
Journal: JAMA (1970)

A Negro soldier developed an acute episode of urticaria and angioedema after ingesting a chloroquine phosphate-primaquine phosphate tablet. A few days later, he also experienced an episode of hemolytic anemia due to a primaquine insult to his glucose-6-phosphate dehydrogenase-deficient red blood cells.
THE CENTER CONTROLLING INTELLECTUAL ACTIVITY.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Oral Surgery.
Authors: Daniel M. Laskin
Journal: JAMA (1963)

Soon after the publication of the first edition in 1948, this book gained recognition as one of the most comprehensive and authoritative texts on oral surgery. In this, the fourth edition, these standards have been maintained. The field of oral surgery, from routine dento-alveolar procedures to the treatment of traumatic injuries, infections, neoplasms, and congenital and acquired deformities, has been covered in an organized and thorough manner. New chapters on surgical anatomy, applied microbiology, and management of emergencies have been added, while most of the others have been considerably revised. These include the sections on treatment of diseases of the salivary glands, oral cysts and tumors, sensory and motor disturbances of the face and jaws, odontogenic diseases of the maxillary sinus, and infections of the head and neck. The references, which significantly include citations from the foreign as well as American literature, have also been brought up to date. The