tbuckley/cabot-search huggingface dataset:
PTOMAIN POISONING VERSUS FOOD-BORNE INFECTIONS
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ovarian Cancer
Authors: Robert J Morgan, Ronald D Alvarez, Deborah K Armstrong, Barry Boston, Lee-may Chen, Larry Copeland, Jeff Fowler, David K Gaffney, David Gershenson, Benjamin E Greer, Perry W Grigsby, Laura J Havrilesky, Carolyn Johnston, Johnathan M Lancaster, Shashikant Lele, Ursula Matulonis, David O'Malley, Robert F Ozols, Steven W Remmenga, Paul Sabbatini, Julian Schink, Nelson Teng
Journal: Journal of the National Comprehensive Cancer Network (2008)

Epithelial ovarian cancer is the leading cause of death from gynecologic cancer and the fifth most common cause of cancer mortality in women in the United States. Fewer than 40% of women with ovarian cancer are cured, and 70% of patients present with advanced disease; because of the location of the ovaries, ovarian cancer has been difficult to diagnose at earlier stages. Epidemiologic studies have identified risk factors, including family history. The NCCN guidelines discuss epithelial ovarian cancer as well as less common ovarian histopathologies, including germ cell neoplasms, carcinosarcomas (malignant mixed Müllerian tumors of the ovary), and ovarian stromal tumors. For 2008, updates include the addition of platinum-based combination therapy as a possible treatment modality for recurrence and a listing of preferred agents for acceptable recurrence modalities. New information was also added to the section on clinical presentation. For the most recent version of the guidelines, please visit NCCN.org
House Calls
Authors: Jack Coulehan
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reply
Authors: A E Gimson, A L W F Eddleston, R. Williams
Journal: Gut (1984)

Serological markers in fulminant hepatitis B SIR,-We were surprised that the interesting study of serological markers in fulminant hepatitis from King's College Hospital1 did not mention the possibility of delta infection in some patients.Delta hepatitis is more likely to result in fulminant hepatic failure than ordinary hepatitis B, as some of the authors have themselves described elsewhere.2In this unit, one third of patients with HBsAg positive fulminant hepatitis have serological markers of acute delta infection,3 and the majority of cases of fulminant delta hepatitis occur in conjunction with acute hepatitis B, as witnessed by positive hepatitis B core IgM tests, rather than in chronic hepatitis B virus (HBV) infection.Although the delta agent requires the presence of HBV to establish itself, it subsequently suppresses the production of HBV markers.This has been best observed in chronic HBV infection complicated by superinfection with delta, both in man4 5 and in chimpanzees.6It is uncertain what happens to HBV replication in acute HBV with delta infection.Patients with acute delta hepatitis are invariably HBsAg positive but the effect of simultaneous delta infection on the level and persistence of markers of acute HBV infection has, as far as we are aware, not been studied.It would be of interest to screen all the patients with fulminant hepatitis described by Gimson et all for markers of acute delta infection, including those who at presentation were already anti-HBs positive.
Interpretation of serologic tests for typhoid fever
Authors: S. A. Schroeder
Journal: JAMA (1968)

Although the incidence of typhoid fever in this country has been decreasing,<sup>1</sup>sporadic outbreaks continue to occur.<sup>2,3</sup>Increasing numbers of military personnel and private citizens are being exposed to typhoid during foreign travel to areas where the disease is endemic; consequently, the diagnosis of typhoid fever remains an important problem. The definitive diagnostic procedure is isolation of<i>Salmonella typhosa</i>from blood, stool, or occasionally, urine, but serologic tests are still widely used. This communication will briefly discuss the following aspects of serologic tests for typhoid fever: the antigens used, cross-reactivity with other salmonellae, traditional interpretive criteria of test results, serologic response in the vaccinated patient, the effect of antibiotic treatment on antibody response, and the Vi test for identifying typhoid carriers. Diagnostic tests for typhoid bacillus, such as Widal's reaction, are tube dilution tests which measure agglutinating antibodies against O and H antigens. The Vi antigen is used
L'Epilessia. Eziologia-Pathogenesi Cura.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Highlights
Journal: JAMA (2019)

To reduce the frequency of order errors, many health systems confi gure their electronic health records (EHRs) to display no more than one patient record at a time.Adelman and colleagues randomly assigned 3356 clinicians and found that a strategy of allowing only one EHR patient record to be open vs a strategy that allowed up to 4 records to be open did not reduce the proportion of wrong-patient order errors.In an Editorial, Wachter and colleagues discuss tradeoff s between safety and effi ciency in the management of clinician workfl ow.
Associations of dietary fat, regional adiposity, and blood pressure in men
Authors: P. T. Williams
Journal: JAMA (1987)

Mediterranean populations have low incidence rates of cardiovascular disease and hypertension that may be due, in part, to dietary factors, particularly a relatively high intake of monounsaturated fat as olive oil. In this study, nutritional components (as grams per 4200 kJ) (1 kcal = 4.2 kJ) from three-day food records were examined in association with resting blood pressure in a cross-sectional survey of 76 sedentary middle-aged American men, aged 30 to 55 years, with resting blood pressures below 160/100 mm Hg. Systolic and diastolic blood pressures correlated significantly and inversely with monounsaturated fat consumption. Polyunsaturated fat consumption also correlated inversely with diastolic blood pressure; however, this relationship became nonsignificant when adjusted for an index of regional adiposity that characterizes the male-type obesity pattern. Detailed analyses of specific fatty acids showed that the correlations with monounsaturates were specific to oleic acid, and the correlation with polyunsaturates was specific to linoleic acid. Multiple regression analysis suggested that 18.2% of the variance in systolic blood pressure and 23.2% of the variance in diastolic blood pressure were related to monounsaturated and polyunsaturated fat consumption and regional adiposity. Thus, increased consumption of monounsaturated fat is related inversely to resting blood pressure, although causality remains to be determined. (<i>JAMA</i>1987;257:3251-3256)
HEALTH BOARDS AND POLITICS.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Advanced Thyroid Carcinoma: Evolving Systemic Therapy Options
Authors: Lori J. Wirth
Journal: Journal of the National Comprehensive Cancer Network (2021)

Although multikinase inhibitors are established therapies in advanced thyroid cancers, treatment-related adverse events can lead to dose reductions and discontinuations, thereby limiting the effectiveness of these treatments. Gene‐specific treatments have emerged as new standard-of-care therapies, and continue to demonstrate efficacy and improved tolerability, although genotyping is needed to identify patients that would benefit from these therapies and more education is needed in regard to the optimal use of these novel agents. Additionally, the emergence of acquired resistance has become a new problem in the field.
Arterial Prostheses
Authors: Leslie W. Ottinger
Journal: JAMA (1976)

<h3>To the Editor.—</h3> In his editorial (235:848, 1976), Dr Hussey called attention to our experience with the USCI ultralightweight knitted Dacron arterial prosthesis (<i>Arch Surg</i>111:146-149,1976). I agree with his general comments concerning the safety and effectiveness of synthetic implanted devices. The unavailability of follow-up studies of the reliability of arterial substitutes is particularly distressing. It should be emphasized, however, that we reported our experience with only one of the numerous prostheses currently available. Though our observations may have general implications, they do not apply specifically to other prostheses, even other ultralightweight knitted Dacron grafts. Some of these newer prostheses will probably prove superior to their heavier predecessors, and it would be incorrect to apply our experience to any other than the single graft we identified.
Spinal Abscess
Authors: Chun C. Kao
Journal: JAMA (1971)

Six years after a back operation, a woman's long-term skin lesions and low-back pain were relieved when an abscess in the lumbar region was discovered and treated. Cutaneous erythema perstans was a cardinal manifestation in this case of spinal suppuration. In the presence of such cutaneous lesions the clinician is obligated to search for possible occult infection or malignancy.
The Stomach and its Ailments Practically Arranged
Authors: W. S. Oke
Journal: BMJ (1859)

married at thie age of 14, but never to have had a child till twenty-two months before admission.She was left in labour on that occasion for four days and iniglhts, anid ultimately delivered by craniotom.Ever since that time, shle had had complete inconltinence of urinie, and had suffered occasionally from at- tacks of inflammationi of the bladder.Slhe was kept under treatmenrt on this account for some weeks after her admission, and also from the loss of appetite and constitutional weakness under wlhich she laboured; and, when she was somewlhat im- proved in these respects, the first operation was performed on Auguist 12tlh.The cleft, having-beeni exposed, was seen to be of very large size, so as to allow the protrusion of a portion of the nmucous membrane of the bladder as large as a walnut.It Was situated at the anterior part of the base of the bladder, ex- tending forward nearly to the uretlhra.Tlhe urethra itself WaS considerably constricted; but, after some little difficculty, a fill sized catlhete was forced into the bladder.The edes were then pared, andl the cleft brought together in the usual way witlh Bozeman's button and six silver sutures, longitudinally.The operation was niecessarily a protractedl one, and she was left under chloroform for an hour, but seemed to bear it tolerably well.The cleft was examinled for the last time on September 16th.It wvas tlheni fouindI to lhave united by first intention in front to srme extent, btnt an orifice remainied behlinid, through which the mucotus membrane of the bladder protruided.Slhe wass sent out of the Hospital on1 October 17th, for the benefit of lher healtlh; and was readmitte(d in January 1859.).Slhc thieni reported that her condition hald not been improved by the operationj as all the urine still ran away.On examining the openingo, it Avas found n mulch larger than after the operation, measuring about an inch and a half iu length, and ratber more than that in breadth.The oper-ation was repeate(d on January 13th; eight silver sutures being ulsed, and the line of urnion made transverse.She was kept uinder chloroform for more than an hour.January 15th.It is noted that she wa-s low and weak, and had no appetite.She did niot complain of pain in the ab(lomcn.Januiary 24th.Slhe still remained in a low state, drowsy, and lisinclined to answver quiestions.The tongue was dry and red; the uirine copious, alkaline, containin, some mucus, but no albumen.The rlate was in positioni, and everything looking well about the wound.No cauise was discovere(d for her symp- toms.January 29lth.She had rigors, and there was said to be a puruileut discharge fiom the rectutmi.The uirine was fcetid and
Error in Key Points, Abstract, Results Section, and Table
Journal: JAMA Network Open (2019)

Estimation of 1-Year Changes in Medicaid Expenditures Associated With Reducing Cigarette Smoking Prevalence by 1%," 1 published April 12, 2019, there were errors in the estimated change in expenditures overall and by state in the Key Points, Abstract, Results section, and Table 2.The overall savings should have been $2.5 billion and the median (range) state savings, $26 million ($10 million to $52 million).This article has been corrected. 1
Is there gender bias in JAMA's peer review process?
Authors: J. R. Gilbert
Journal: JAMA (1994)

<h3>Objective.</h3> —To assess whether manuscripts received by<i>JAMA</i>in 1991 possessed differing peer review and manuscript processing characteristics, or had a variable chance of acceptance, associated with the gender of the participants in the peer review process. <h3>Design.</h3> —Retrospective cohort study of 1851 research articles. <h3>Setting.</h3> —<i>JAMA</i>editorial office. <h3>Participants.</h3> —Eight male and five female<i>JAMA</i>editors, 2452 male and 930 female reviewers, and 1698 male and 462 female authors. <h3>Main Outcome Measure.</h3> —Statistically significant gender bias. <h3>Results.</h3> —Female editors were assigned manuscripts from female corresponding authors more often than were male editors (<i>P</i>&lt;.001). Female editors used more reviewers per manuscript if sent for other review. Male reviewers assisted male editors more often than female editors, and male reviewers took longer to return manuscripts than did their female counterparts (median, 25 vs 22 days). Content reviewer recommendations were independent of corresponding author and review gender, while male statistical reviewers recommended the highest and lowest categories more frequently than did female statistical reviewers (<i>P</i>&lt;.001). Manuscripts handled by female editors were rejected summarily at higher rates (<i>P</i>&lt;.001). Articles submitted to<i>JAMA</i>in 1991 were not accepted at significantly different rates based on the gender of the corresponding author or the assigned editor (<i>P</i>&gt;.4). <h3>Conclusions.</h3> —Gender differences exist in editor and reviewer characteristics at<i>JAMA</i>with no apparent effect on the final outcome of the peer review process or acceptance for publication. (<i>JAMA</i>. 1994;272:139-142)
Lack of association between type of hepatitis C virus, serum load and severity of liver disease . Institute of Internal Medicine, University of Milan, Italy; *Epidemiology Unit, Aviano Cancer Center, Aviano, Italy; **Department of Medical Microbiology, University of Edinburgh, United Kingdom
Journal: Hepatology (1995)

A quantitative nucleic acid sequence-based amplification assay (NASBA-QT) for detection of hepatitis C virus RNA (HCV-RNA) was evaluated and compared with the HCV branched-DNA (bDNA) assay (Chiron Corporation) and the HCV MONITOR assay (Roche Diagnostic Systems). For this evaluation five panels were designed: (1) serial dilutions of genotype 1b in-vitro HCV-RNA; (2) standards of in-vitro HCV-RNA genotypes 1a, 1b, 2, 3, 4, and 5; (3) a proficiency panel consisting of 12 HCV-RNA positive plasma samples of different genotypes and HCV-RNA concentrations and a genotype 1a and 1b 3-fold dilution series; (4) a panel of 67 HCV-RNA positive plasma samples obtained from patients with HCV infection and (5) an HCV-RNA positive control sample, diluted 50-fold in 25 different HCV-RNA negative plasma samples. The quantitative detection limit was found to be 103 copies per 100 μl and the qualitative detection limit 102.3 per 100 μl. The amplification efficiency was independent of the plasma matrix, but dependent on the HCV genotype. The HCV NASBA-QT assay was more than 10 times as sensitive as the bDNA assay while the quantitative results of both assays were highly concordant. The HCV NASBA-QT assay was comparable in sensitivity with the HCV MONITOR assay, but the HCV MONITOR assay yielded consistently lower values. It is concluded that the HCV NASBA-QT assay is a reliable assay for quantitative HCV-RNA detection in various settings.
Successful treatment of middle aged and elderly patients with end stage renal disease
Authors: C S Ogg, D. Taube, D G. Williams
Journal: BMJ (1983)

Many patients over the age of 55 with end stage renal disease in the United Kingdom are denied dialysis or transplantation.Although the reasons are complex, anticipation of a poor prognosis for these patients might explain why most British renal units impose an arbitrary age limit on the acceptance of patients for treatment.A study was therefore conducted to examine the prognosis and quality of life of 64 patients (mean age 59-6 years, range 55-72) accepted into our renal replacement programme from the beginning of 1975.The five year survival of the patients was 62 0%, with 78 1% of the survivors either having successful transplants or caring for themselves using home haemodialysis or continuous ambulatory peritoneal dialysis.The results show that in terms of survival, economics, and rehabilitation it is both feasible and reasonable to Renal Unit, Guy's Hospital,
House Calls
Authors: Sandeep Jauhar
Journal: New England Journal of Medicine (2004)

In 1930, 40 percent of all doctor–patient visits were house calls. By 1980, the proportion had dwindled to less than 1 percent. Even in the 1990s, in the midst of an explosion in the home care business, the number of house calls continued to drop. At conferences, home care professionals were reported to laugh outright at the mere mention of physician involvement in home care.1 (Figure)Doctors approach house calls much as politicians approach campaign finance reforms: everyone thinks they're a good idea, but few do anything to support them. A major reason, not surprisingly, is money. Traveling to . . .
CAN MONILIA DO HARM?
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal