tbuckley/cabot-search huggingface dataset:
AIR CONDITIONS AND HEALTH
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Respiratory effects of lipopolysaccharide-induced inflammatory lung injury in mice
Authors: D.S. Faffe, V.R. Seidl, P.S.C Chagas, V.L Gonçalves de Moraes, V.L. Capelozzi, P.R.M. Rocco, W.A. Zin
Journal: European Respiratory Journal (2000)

The pathogenic mechanisms of lipopolysaccharide (LPS)-induced lung injury have not been classified. This study examined the physiological changes after endotoxin inhalation and related those to features of pulmonary inflammation in mice. Pulmonary mechanics, histopathology, and bronchoalveolar lavage fluid (BALF) from BALB/c mice were analysed at different occasions (3, 24, 48 and 72 h) after inhalation of saline or LPS from Escherichia coli (0.3 (L0.3) or 10 mg x mL(-1) (L10)). Mice were sedated, anaesthetized, and ventilated. After chest wall resection static (Est) and dynamic (Edyn) elastances, deltaE (Edyn-Est), resistive (deltaP1) and viscoelastic/inhomogeneous pressures (deltaP2), and deltaP1+deltaP2 (deltaPtot) were obtained by end-inflation occlusion method. Lungs were prepared for histopathology. In parallel groups, tumour necrosis factor (TNF)-alpha, neutrophils, and protein were evaluated in the BALF. L0.3 and L10 showed a time-dependent production of TNF-alpha preceding a massive neutrophil infiltration. In L10 BALF there was an increase in protein level at 24 and 48 h. Est and Edyn increased early in L0.3 (65%, 63%) and L10 (41%, 51%). In L10 deltaE, deltaP2, and deltaPtot showed a gradual rise. At 72 h all groups were similar. L0.3 showed an early increase in cellularity, which returned to normal at 72 h. L10 presented the same pattern with the cell count remaining elevated until 72 h. In conclusion, lipopolysaccharide inhalation led to elastic and viscoelastic pulmonary changes together with tumour necrosis factor-alpha production and neutrophil infiltration in mouse lung.
SUBDURAL HEMORRHAGE
Authors: Charles D. Aring
Journal: JAMA (1960)

Subdural hematoma is an adversary apt to lull the physician into a diagnosis that becomes a death warrant. It is a relievable condition when it is recognized promptly. There is justification, therefore, in repeatedly calling its multifarious syndromes to the attention of physicians. In subdural hemorrhage, blood accumulates beneath the dura; the source of the bleeding almost always is venous. Many thin-walled veins bridge the space between brain and the dura, and the force that sheers one or more of them can be relatively minor if it is delivered under proper conditions and in the right direction. In not a few cases, a blow of analogous force has been experienced many times previously without trouble. If the patient is suffering from a blood dyscrasia or is receiving anticoagulants, it is thought that there need be no trauma to produce subdural bleeding; it may then occur in the ordinary course of
The Mystic Statistic
Authors: Stanley S. Schor
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Method for evaluating function of the neurogenic bladder
Authors: A. S. Abramson
Journal: JAMA (1966)

Normal voiding is associated with a complex of reflex physiological events involving the somatic and autonomic nervous systems. Thus, detrusor contraction is accompanied by relaxation of the external urinary and rectal sphincters which ordinarily are in a state of tonic contraction. It is also accompanied by a slight rise in blood pressure and pulse rate. Neurogenic disorders, such as those produced by transverse myelopathy, result in changes in timing and intensity of these events. Single methods of examination or testing such as cystoscopy, cystometry, sphincterometry, urethrography, electromyography of the bladder wall, electromyography of striate-muscle sphincters, flowmetry, and cineradiography, when used alone, are not adequate to demonstrate the physiological or pathophysiological events in an integrated and dynamic fashion. A method, adaptable to clinical use, of simultaneous recording of intracystic pressure, indirect monitoring of the activity of the external urinary sphincter from the rectal sphincter, pulse rate, and blood pressure throughout bladder
Implicationes Psychiatric del Problemas de Adolescentes
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 1856: Transplantation of Bone-marrow Mononuclear Cells into the Infarcted Heart has Favorable Engraftment Compared to Mesenchymal Stem Cells, Skeletal Myoblasts and Fibroblasts
Authors: Koen E van der Bogt, Ahmad Y Sheikh, Sonja Schrepfer, Grant Hoyt, Feng Cao, Katie Ransohoff, Christopher H Contag, Robert C Robbins, Joseph C Wu
Journal: Circulation (2007)

Introduction: A comparative analysis of the efficacy of different cell candidates for the treatment of heart disease remains to be described. This study aimed to evaluate the therapeutic efficacy of 4 cell types in a murine model of myocardial infarction. Methods: Bone-marrow cells (MN), mesenchymal cells (MSC), skeletal myoblasts (SkMb) and fibroblasts (Fibro) were isolated from male L2G transgenic mice (FVB background) that express firefly luciferase (Fluc) and green fluorescence protein (GFP). Cells were characterized by flow cytometry, bioluminescence imaging (BLI), and luminometry. Female FVB mice (n=60) underwent LAD ligation and were randomized into 5 groups to intramyocardially receive one cell type (5 × 10 5 ) or PBS. Cell survival was measured in vivo by BLI and ex vivo by TaqMan PCR at week 6. Cardiac function was assessed by echocardiography and invasive hemodynamic measurements at week 6. Results: Fluc expression correlated with cell number in all groups (r 2 &gt;0.93). In vivo BLI revealed donor cell death of MSC, SkMb, and Fibro within 3 weeks after transplantation. By contrast, cardiac signal was still present after 6 weeks in the MN group, as confirmed by PCR (p&lt;0.01). Echocardiography showed significant preservation of fractional shortening in the MN group compared to controls (p&lt;0.05). Measurements of left ventricular end-systolic/diastolic volume revealed the least amount of ventricular dilatation occurred in the MN group (p&lt;0.05). Conclusion: This is the first study to directly compare a variety of cell candidates for myocardial therapy and indicates that MN exhibit a favorable survival pattern, which translates into preservation of cardiac function.
Mechanism of enhanced susceptibility of hypertrophied heart to acquired torsade de pointes arrhythmias Keiji Yamamoto, Dmitry O. Kozhevnikov, Dionyssios Robotis, Mark Restivo, Nabil El-Sherif. VA NY Harbor Healthacre System, Brooklyn, NY, SUNY Health Science Center, Brooklyn, NY
Journal: Journal of the American College of Cardiology (2001)
Liver
Authors: R England, D Martin, R Walmsley, M Zhao, M Hamilton, P Chapman, J Dooley, A Wakefield, C Lockwood
Journal: Gut (1996)

The accepted mnement ofMirizi's syndrome (MS) is surgical but in patients who are not fit for surgery, endoscopic and percutaneous management have been described.Our aim was to review retrospectively our experience ofendoscopic intervention for MS.ERCP reports of all patients presenting for endoscopic management of choledocholithiasis between March 1989 and June 1995 were reviewed.Those with cholangiographic evidence ofMS were selected for study.Patient records and cholangiograms were reviewed and follow-up was recorded from the notes or by telephone contact with patients, their relatives, or doctors.Between March 1989 and June 1995. 25patientshadMS dia d cholangiographically.There were 16 females and 9 males, median age 67 years (range 28-91). 10presented with painlessjaundice, 9 with pam and jaundice, 4 with cholangitis, and 2 had pain only.None presented with a clinical diagnosis ofacute cholecystitis.Cholangiographically, 15 had Mirizzi Type I and 10 had Mirizzi Type 2. 2 patients had no endoscopic therapy and were referred for surgery. 9patients had preliminary endoscopic therapy: Endoscopic sphinterotomy (ES) (6); CBD stenting (6); GB stenting (1); cystic duct stone disimpaction & ESWL ofGB (1); mechanical lithotripsy (ML) (2).These patients subsequently had surgery at median time of 15 days range (1-150) post ERCP.The remaining 14 patients had endoscopic therapy consisting ofES (13), CBD stenting (11); GB stenting (1); CBD and GB stenting (2); cystic duct stone disipaction (3).In addition to biliary drainage, ESWL, ML, and dissolution agents were used in 7 of 14. Ofthese 14, 3 were discharged with clear ducts, 9 had long-term stenting, and 1 is awaiting surgery, I awaiting ESWL GB.Complications occurred in 4/25 post ERCP: liver abscess (1), bronchopneumonia (1), secondary biliary cirrhosis (1) and acute cholecystitis (1).Endoscopic therapy ofMS is feasible, safe and efiective as a temporsing measure before surgery and can be definitive treatment for those considered unsuitable surgical candidates.
DEHYDRATED VEGETABLES
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Thymosin treatment of chronic hepatitis B: A placebo-controlled pilot trial
Authors: M Mutchnick
Journal: Hepatology (1991)

Chronic hepatitis B is a severe and frequently progressive disease. We assessed the safety and efficacy of thymosin fraction 5 and thymosin-α1 in a prospective, placebo-controlled trial in 12 patients with chronic hepatitis B. All patients had histological and biochemical evidence of active liver disease for at least 6 mo before treatment and were positive for serum hepatitis B virus DNA and HBsAg. Seven patients received thymosin fraction 5 or thymosin-α1 and five patients received placebo twice weekly for 6 mo. By the conclusion of the study (1 yr), serum aminotransferase levels had improved significantly in thymosin-treated patients, but not in the placebo group. Six (86%) of the thymosin treated patients and one (20%) patient given placebo cleared hepatitis B virus DNA from serum (p < 0.04, Fisher's exact test). After treatment, replicative forms of hepatitis B virus DNA were present in the liver specimens of four of five placebo-treated patients but in only one of seven thymosin-treated patients (p < 0.04, Fisher's exact test). Response to thymosin therapy was associated with significant improvements in peripheral blood lymphocyte and CD3 and CD4 counts and in in vitro production of interferon-γ over initial values. No significant side effects were observed in patients given thymosin or in placebo-treated patients. Clinical, biochemical and serological improvement in patients responding to thymosin were sustained during 26 ± 3 mo of follow-up. The results of this pilot trial suggest that thymosin therapy promotes disease remission and cessation of hepatitis B virus replication in patients with chronic viral infection.
THE SMEGMA BACILLUS.
Authors: OSCAR A. DAHMS
Journal: JAMA (1900)

<h3>THE SIGNIFICANCE OF THE SMEGMA BACILLUS IN THE DIAGNOSIS OF TUBERCULOSIS AND SYPHILIS.</h3> Repeated allusions have been made to the striking similarity which exists between the smegma bacillus and the bacillus of syphilis, of tuberculosis, and of lepra. It is obvious that errors in the diagnosis of these diseases, especially of tuberculosis, might lead to serious consequences, and it is further apparent that because of the close resemblance between these microscopic forms there exists a dangerous possibility of the occurrence of such mistakes whenever a diagnosis is to be based on the detection of the presence of the specific bacillus in physiologic or pathologic fluids and secretions. For these reasons it has been the aim of many experimenters to devise infallible differential stains for these organisms. Considering the comparative unimportance of a differentiation between smegma and lepra bacilli, no further attention will be devoted to that subject here, but the
Rheology of Blood in the Microvasculature
Authors: Roe E. Wells
Journal: New England Journal of Medicine (1964)

DextransNear the end of World War II a vigorous search for plasma and blood substitutes was still under way. In 1945 Grönwall and Ingelman67 suggested the use of the polysaccharide dextran, a material obtained from the breakdown of sucrose by the bacterium Leuconostoc mesenteroides. They observed that the native material caused marked aggregation of erythrocytes and appeared to produce death by generalized embolization of the capillaries. If the material was hydrolyzed, this massive aggregation did not occur. These observations led Thorsén and Hint68 to explore in detail the mechanism of the effects of dextran upon the suspension stability of . . .
Testimonial Banquet in Honor of Dr. Nathan Smith Davis
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TYPHOID FEVER IN 1923
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Trends in HIV- and STD-Related Risk Behaviors Among High School Students—United States, 1991-2007
Journal: JAMA (2008)

Persons who engage in unprotected sexual intercourse or use injection drugs are at increased risk for human immunodeficiency virus (HIV) infection and sexually transmitted diseases (STDs). Changes in HIV- and STD-related risk behaviors among high school students in the United States during 1991-2005 were reported previously. To update these analyses through 2007, CDC analyzed data from nine biennial national Youth Risk Behavior Surveys (YRBS). This report summarizes the results of that analysis, which indicated that, during 1991-2007, the percentage of U.S. high school students who ever had sexual intercourse decreased 12%, the percentage who had sexual intercourse with four or more persons during their lifetime decreased 20%, and the percentage who were currently sexually active decreased 7%. Among students who were currently sexually active, the prevalence of condom use increased 33%. However, these changes in risk behaviors were not observed in some subgroups. In addition, no changes were detected in the prevalence of sexual risk behaviors from 2005 to 2007, and many students still engaged in behaviors that place them at risk for HIV infection and STDs. Additional efforts to reduce sexual risk behaviors, particularly among black, Hispanic, and male students, must be implemented to meet the Healthy People 2010 national health objective for adolescent sexual behaviors (objective no. 25-11) and to decrease rates of HIV infection and STDs.
The Standard Medical Directory of North America, Consisting of Twelve Parts, Including Directory of Physicians of North America, Medical Colleges. Medical Service of the United States, Medical Societies, Medical Practice Acts, Medical Publications (Including Books and Periodicals), Mineral Springs, Drugs and Medicines, Medical and Surgical Products, Manufacturers and Life Insurance Companies.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal