tbuckley/cabot-search huggingface dataset:
Abstract 19533: The Relationship Between Aortic-brachial Stiffness Mismatch and Mean Blood Pressure
Authors: Catherine Fortier, Mohsen Agharazii
Journal: Circulation (2015)

Background: Carotid-femoral pulse wave velocity (cf-PWV) is considered to be the gold standard for assessment of aortic stiffness. The impact of aortic stiffness on peripheral end-organ damage is explained by the loss or reversal of physiological impedance mismatch between aorta and medium-sized muscular conduit arteries. The main limitation of cf-PWV is its positive relationship with mean blood pressure. Recently, we have shown that assessment of aortic-brachial stiffness mismatch (PWV ratio) outperforms cf-PWV for the prediction of mortality in dialysis population. As both carotid-radial PWV (cr-PWV) and cf-PWV depend on blood pressure, we hypothesized that PWV ratio is not influenced by mean blood pressure. Method: In 310 dialysis patients (median age of 67 years [25 th -75 th percentiles: 56 - 76], 185(60%) men, 134 (43%) diabetes and 162 (52%) cardiovascular disease), cf-PWV and cr-PWV were measured using direct distance (Complior) and maximal upstroke algorithm. Mean blood pressure was obtained using arterial tonometry calibrated with brachial systolic and diastolic blood pressures in a controlled environment. In a linear regression analysis, we examined the relationship between MBP and cf-PWV, cr-PWV and PWV ratio. Results: The mean cf-PWV, cr-PWV, PWV ratio and MBP were respectively 13.52±4.06 m/s, 8.76±1.68 m/s, 1.59±0.52 and 92±16 mmHg. The linear relationships between MBP, cf-PWV and cr-PWV are shown in figures 1A-B. However, there were no relationship between MBP and PWV ratio (Figure 1C). There were no interaction between age, gender and the absence of a relationship between MBP and PWV ratio. Conclusion: As PWV ratio is mechanistically a logical parameter for explaining target organ damage and it has no significant relationship with MBP, it seems to be an ideal index for macro-circulatory disease. These findings need to be validated in independent cohorts.
Coronary Gas Endarterectomy
Authors: Martin J. Kaplitt
Journal: JAMA (1971)

Gas endarterectomy has been utilized in 14 patients to secure a complete surgical correction of the totally occluded and diffusely diseased right coronary artery. In ten patients we studied angiographically, patency was demonstrated in nine instances. In five of these patients the reopened right coronary artery was seen to be filling the left coronary tree from many branches now free of disease. It is our impression that coronary gas endarterectomy is the procedure of choice for correction of the diffusely diseased right coronary artery.
Australian Rheumatism Association: ANNUAL MEETING, 1967
Journal: Annals of the Rheumatic Diseases (1968)

patients present usually without acute crystal synovitis.We have seen only two patients, both previously suspected of having rheumatoid arthritis, with an acute attack of synovitis, although in six others there was a welldocumented history.DR. P. HOLT (London): Have you any idea what the mechanism is?What happens if you put iron into the joint in an experimental animal?DR.HAMILTON: We have no idea of the mechanism except that iron must be involved in some way; calcium pyrophosphate is normally broken down to orthophosphate and iron may perhaps inhibit the pyro- phosphates from producing its deposition in the joints.It is very difficult to produce haemochromatosis in laboratory animals, although I understand this can be done using special techniques.We have not injected iron into experimental animals.DR. SEYMOUR (London): We are proposing to do this in the rat to see if we can produce a haemochromatosis arthritis.I think the variation in the amount of iron present in the synovial tissue reported by different authors reflects the amount of venesection that the patients have had.It is easy to obtain a fall in serum iron before all the iron has come out of the tissues; if you wait awhile the serum iron will come up again as more comes out of the tissues.Our two patients had been extensively venesected and we were able to show no iron chemically or histologically.DR. L. SIMON (Montpellier): We have found four cases of arthropathy in twenty cases of primary haemochroma- tosis.In another case of diabetes mellitus with chondrocalcinosis and arthropathy, liver biopsy revealed haemo- chromatosis without skin pigmentation or hepatomegaly.The combination of isolated diabetes mellitus and chondrocalcinosis with arthropathy suggests haemo- chromatosis.Transient Idiopathic Osteoporosis of the Hip.*By M. LEQUESNE (Paris).
CANCER STATISTICS AS THEY APPEAR TO A PATHOLOGIST
Authors: H. GIDEON WELLS
Journal: JAMA (1927)

The medical scientist is not concerned with the prevailing use of statistics, as described recently by Professor Ripley: "Statistics are not intended primarily to tell the truth. They are uttered for the purpose of proving a point." The scientist wants his statistics to prove something, and especially he wants them to be unuttered when they do not "primarily tell the truth." The publication of statistics on cancer has occupied much space in the medical literature for many years, so that there is no lack of material for consideration, yet it seems not unfair to state at this time that there are few if any facts concerning cancer that can be established beyond dispute by the published statistical data. The statistics certainly fail to prove any points, even if not intentionally untruthful. No matter what the question may be, the statistics that have been published will be found to
Computer-assisted instruction in nuclear medicine
Authors: D. W. Brown
Journal: JAMA (1968)

As part of a broad project evaluating many uses of the computer in nuclear medicine, we are studying its potential role in teaching. Two computer systems are being used. One uses a teletype machine connected by telephone line to a time-sharing computer. This system is practical and relatively inexpensive. The other system is more flexible and uses a typewriter-keyboard connected on-line to a process-control computer. New computer languages have greatly simplified writing courses for these computers. We have tested ten courses designed for radiology residents and technologists and have shown that computer-assisted instruction is an effective method of teaching certain aspects of nuclear medicine. At present we are involved in trying to prove that in limited situations it offers advantages over more classic teaching methods.
Early Organotherapy and Talismans
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AMA Sponsors Conference on Blood Banking
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CHILDISH HABIT
Authors: F A KINGERY
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Surgery of the Head and Neck.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Management of the Difficult Septum
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 21357: Qt Intervals During Nighttime Sleep and Circadian Autonomic Activities in Healthy and Long Qt Syndrome (lqts) Infants
Authors: Masao Yoshinaga, Shunji Seki, Hiroya Ushinohama, Seiko Ohno
Journal: Circulation (2017)

Background: Few data were available about the QT intervals during nighttime/daytime sleep and daytime activity, and circadian autonomic nerve activities in healthy and LQTS infants. Methods: Holter ECGs were recorded in infants with 12 LQTS infants (2 KCNQ1 , 5 KCNH2 , and 5 not mutation-identified; 12±7 weeks after birth; M/F=6/6) before treatment. Ten age-matched healthy infants (M/F=4/6) were evaluated at the same period (12±3 weeks) and at 40±6 weeks. Three consecutive QT/RR intervals were measured at maximum (max), minimum, and mean heart rates (HRs) at nighttime/daytime and daytime activity and QT intervals were corrected by Bazett’s formula. The power spectral density was computed hourly as low-frequency (LF) and high-frequency (HF) components and was log-transformed. Ln(HF) and the ratio of Ln(LF)/Ln(HF) were used as surrogate markers of para-sympathetic activity and sympathovagal balance, respectively. Results: LQTS infants showed a significantly longer QTc value (490±19 ms) at max HR at nighttime sleep than that (478±20 ms, P =0.008) at max HR in daytime sleep; On the other hand, healthy infants showed no difference in the QTc values between nighttime and daytime sleep in both early and late infantile periods (439 vs 435 in early and 433 vs 423 ms in late infantile periods, respectively). LQTS infants showed a significantly decreased (or premature) parasympathetic than controls during early infancy during nighttime (Figure). In healthy controls, nighttime parasympathetic activity significantly increased at late infancy. QTc values during nighttime sleep was inversely associated with parasympathetic activity ( P =0.002) and positively associated with sympathovagal imbalance ( P &lt;0.001). Conclusions: In early infantile periods, parasympathetic activity was not fully functioned, especially in LQTS infants. A long QTc values associated with impaired autonomic activity during nighttime sleep is one of risk factors of lethal arrhythmia in LQTS infants.
WHITHER?
Journal: Annals of Internal Medicine (1942)

Article1 May 1942WHITHER?JAMES ALEXANDER MILLER, F.A.C.P.JAMES ALEXANDER MILLER, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-16-5-1003 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe question which I have posed as the subject of my address this evening is on the lips or in the hearts of millions of the population of the world today.It is obvious that I can have no intention of addressing myself to that vast audience. It is rather my purpose to suggest a searching of hearts and minds to our profession here in America and particularly to that portion of it which is represented in the Fellowship of the American College of Physicians. It was my thought that this Annual Convocation is especially timely for such introspection, inasmuch... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Convocational Oration, American College of Physicians, Twenty-fifth Annual Session, Boston, Mass., April 23, 1941. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRestraining Forced Marriage 1 May 1942Volume 16, Issue 5Page: 1003-1010KeywordsFellowshipsHeart ePublished: 1 December 2008 Issue Published: 1 May 1942 PDF downloadLoading ...
Individualization of drug therapy for the parkinsonian patient
Journal: JAMA (1975)

<b>Dr. Lamar:</b>Our discussion today will focus on the need to individualize the total management of a parkinsonian patient to assure an optimal therapeutic benefit. This approach is especially important because of the well-recognized, remarkable variation in therapeutic response that exists among parkinsonian patients and even within the same patient from day to day. Perhaps 15% of parkinsonian patients do not achieve even a modicum of desired therapeutic response from one or more of the antiparkinsonian drugs they receive, while an equal proportion of patients derive intolerable drug side-effects—sometimes at low doses. Other patients may suffer from drug-drug interactions following coadministration of two or more antiparkinsonian drugs. The objective of this round is to discuss factors that must be considered to achieve optimal therapeutic results in the management of parkinsonism. The moderator of this conference will be Dr. Joseph R. Bianchine. <b>Dr. Bianchine:</b>Dr. Gordon, will you define Parkinson disease
Malnutrition and hypernatremic dehydration in breast-fed infants
Authors: T. W. Rowland
Journal: JAMA (1982)

Despite the well-recognized advantages of breast-feeding to both mother and child, malnutrition of breast-fed infants can occur. We report two cases of breast-fed infants with cachexia, hypernatremia, and, in the one case in which it was measured, an elevated level of breast-milk sodium. These cases, along with several reported previously, emphasize the need for proper education and close and early follow-up of the nursing mother and infant, especially since a lack of parental awareness can be part of this syndrome. (<i>JAMA</i>1982;247:1016-1017)
UMBILICAL INFECTION WITH BACILLUS PYOCYANEUS IN THE NEWBORN.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Recent opinions of the Judicial Council of the American Medical Association
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Oncarnoviruses
Authors: James E. Parker
Journal: JAMA (1976)

<h3>To the Editor.—</h3> The isolation of type C virions from a normal human fibroblast strain described by Panem et al (<i>Science</i>189:297, 1975) received banner headlines in your medical news of July 28. While this ties in nicely with the extensive work performed on inbred mice over recent years and can be reconciled with the ubiquitous oncogene hypothesis of Todaro and Huebner, it might perhaps be considered in another light. Extensive work by our veterinary colleagues has demonstrated that in most species it is now recognized that there are two main groups of oncarnoviruses. In cats, for instance, feline leukemia virus, which is oncogenic, causes immunosuppression and a variety of other diseases and is transmitted horizontally. The second group comprises the endogenous feline oncarnoviruses; the latter genome has been detected in DNA and RNA of all cat-cell cultures and tissues tested. While these viruses are morphologically indistinguishable from feline leukemia
Gifts to Physicians From Industry-Reply
Authors: Richard J. McMurray
Journal: JAMA (1991)

<h3>In Reply.</h3> —Goldstein's data raise questions about the extent to which certain of the AMA's guidelines are being observed. Physicians should not be receiving cameras and tape recorders (or even stuffed animals) from drug companies. However, there is reason to believe that the guidelines are having a substantial effect on the promotional practices of industry, particularly with regard to the more egregious abuses. For example, we believe that companies have stopped their practice of paying travel expenses for physicians and their spouses to attend company-funded conferences. To ensure greater adherence to the guidelines, we are developing measures for monitoring and enforcement. We are also forwarding reports of violations, including Goldstein's letter, to the Pharmaceutical Manufacturers Association so that it can take appropriate action with respect to its member companies. LeBlond and Leung and Robson raise important concerns about physicians who serve as consultants to industry or who receive research funding