tbuckley/cabot-search huggingface dataset:
Controversy over Multiple Chemical Sensitivities
Authors: Jacqueline Krohn
Journal: Annals of Internal Medicine (1994)

Letters1 February 1994Controversy over Multiple Chemical SensitivitiesJacqueline Krohn, MD, Jill Ryan, BA, and Julie Jacobson, PhD, MS, RNJacqueline Krohn, MDLos Alamos Medical Center; Los Alamos, NM 87544Search for more papers by this author, Jill Ryan, BALos Alamos Medical Center; Los Alamos, NM 87544Search for more papers by this author, and Julie Jacobson, PhD, MS, RNLos Alamos Medical Center; Los Alamos, NM 87544Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-3-199402010-00025 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Simon and colleagues [1] appear to present a case–control study comparing chemically sensitive patients with controls without specific and measurable prestudy hypotheses. The results are useful only to develop recommendations for future studies, and only if the study was done adequately. However, flaws in participant selection and the information collected probably biased their results.Simon and colleagues selected patients with a computer billing code of multiple allergy, and then screened for illness lasting 3 months or more, multisystem involvement (including the central nervous system), and self-report of sensitivity to chemicals. With no screening for length, type or ...References1. Simon GE, Daniell W, Stockbridge H, Claypoole K, Rosenstock L. Immunologic, psychological, and neuropsychological factors in multiple chemical sensitivity: a controlled study. Ann Intern Med. 1993; 19:97-103. Google Scholar2. Bell IR, Schwartz GE, Peterson JM, Amend D. Self-reported illness from chemical odors in young adults without clinical syndromes or occupational exposures. Arch Environmental Health. 1993; 48:6-13. Google Scholar3. Robin LN, Helzer JE, Croughan J, Ratcliff KS. National Institute of Mental Health Diagnostic Interview Schedule. Its history, characteristics, and validity. Arch Gen Psychiatry. 1981; 38:381-9. Google Scholar4. Fledler N, Maccia C, Kipen H. Evaluation of chemically sensitive patients. J Occup Med. 1992; 34:529-38. Google Scholar5. Morrow LA, Callender T, Lottenberg S, Bucshsbaum MS, Hodgson MJ, Robin N. PET and neurobehavioral evidence of tetrabromoethane encephalopathy. J Neuropsychiatry Clin Neurosci. 1990; 2: 431-5. Google Scholar Author, Article, and Disclosure InformationAffiliations: Los Alamos Medical Center; Los Alamos, NM 87544 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1994Volume 120, Issue 3Page: 249-251KeywordsAllergy and immunologyAnxietyBrain damageCentral nervous systemComputersEmotionsForecastingMemoryMusculoskeletal injury ePublished: 15 August 2000 Issue Published: 1 February 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Table Errors
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Innovations
Authors: M. Arvanitakis, J. Devière
Journal: Endoscopy (2007)

Since the introduction of flexible endoscopy over 40 years ago, numerous technical achievements have contributed to further development in diagnostic as well as therapeutic applications. This expansion continues as medical centers across the world are now devoting substantial resources to research and technical innovation in endoscopy. The present review summarizes five pertinent papers published in the past year concerning novel technologies in endoscopy; three regard advances in diagnosis [1] [2] [3] and two consider new therapeutic techniques [4] [5].
Closing the gap: the burden of unnecessary illness
Authors: J. Carter
Journal: JAMA (1985)

Improvements in medical technology and health care have led most Americans to expect long and healthful lives. In part, these expectations have been realized. Nevertheless, despite remarkable accomplishments by the American medical community, there exists a gap between what is and what could be the health of the American people. Hundreds of thousands of illnesses and deaths occurring each year are unnecessary in light of currently available medical knowledge. Such occurrences pose a double burden for our nation: the impact on the victims themselves, and the diversion of medical resources from unavoidable health problems. Recognizing this condition, I directed The Carter Center (established at Emory University shortly after I left the White House) to determine the factors most responsible for unnecessary morbidity and mortality in the United States, and to recommend intervention strategies to reduce or eliminate those factors. The Carter Center consultants analyzed the burden imposed by cancer, heart
Floaters
Authors: David Weinstock
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Error in Results
Authors: Katharina Dohm, Dario Zaremba, Udo Dannlowski
Journal: JAMA Psychiatry (2018)

Max Lam, PhD; Jimmy Lee, MD; Attilio Rapisarda, PhD; Yuen Mei See, BPsych; Zixu Yang, MSocSci; Sara-Ann Lee, BSocSci; Nur Amirah Abdul-Rashid, BPsych; Michael Kraus, MSc; Mythily Subramaniam, MD; Siow-Ann Chong, MD; Richard S. E. Keefe, PhD
Highlights from this issue
Authors: The Triumvirate
Journal: Thorax (2019)

Stravinsky's ballet score details a pagan ritual in which a sacrificial virgin dances herself to death.This is a far step away from the clinical trial performed by Carmen Houben and colleagues (see page 328) which investigated nurse-led advanced care planning in patients with advanced COPD and their loved ones.This multicentre cluster randomised-controlled trial delivered a structured 90 min advanced care planning session to patients and their loved ones.165 patients were randomised with quality of patient-physician end-of-life care communication higher in the intervention group.In addition, anxiety symptoms were lower in loved ones and similar in the patients in the intervention and control group at 6 month follow-up.Depression in both patients and loved ones were similar.So, a nurse-led ACP-intervention session improves end-oflife care communication without causing psychosocial distress in both patients and loved ones.Now that is something to dance about.
TV report on DTP galvanizes US pediatricians
Authors: E. R. Gonzalez
Journal: JAMA (1982)

Television viewers were terrified. Physicians' phones were ringing off the hook. To Harry Jennison, MD, executive director of the American Academy of Pediatrics (AAP), Evanston, Ill, it was reminiscent of the polio scare in the early 1950s. "Parents were hysterical," he says. In the Cleveland, Ohio area, "it was devastating in every pediatrician's office," according to Shaker Heights pediatrician Leonard P. Rome, MD, chairman of the AAP's Chapter Chairmen's Committee. "Doctors were calling each other and saying, 'Are you still giving pertussis [vaccine]?' " (Some physicians actually did halt pertussis immunizations temporarily.) In the mountains of northern New Mexico, "inquiries about the vaccine have increased 25%," estimates Española pediatrician James D. Waltner, MD. And as far west as the Pacific coast, "we have had a lot more explaining to do," says Robert Meechan, MD, professor of pediatrics at the Oregon Health Sciences University in Portland and director of the university's pediatric
Caution of Conclusions of a Meta-analysis Including Problematic Trials
Authors: Michael Schatman, David Dibenedetto, Ronald Kulich, Beth Darnall, Maisa Ziadni, Richard Stieg
Journal: JAMA Internal Medicine (2018)

Sarah Cockayne, MSc; Joy Adamson, PhD; Susan Lanham-New, PhD; Martin J. Shearer, PhD, MRCPath; Simon Gilbody, DPhil; David J. Torgerson, PhD
瘢痕瘤病中的CD45RO+记忆T淋巴细胞的特征
Authors: Z. Chen, L. Zhou, T. Won, Z. Gao, X. Wu, L. Lu
Journal: British Journal of Dermatology (2018)

Summary 瘢痕瘤是一种类似于蔓生伤疤的疤痕,甚至会比原始的伤口更大或更明显。这种疾病在深色皮肤中最为常见。尽管瘢痕瘤的确切原因尚属未知,但我们知道其中涉及免疫系统。记忆T淋巴细胞可以针对病原体(有害细菌或病毒)提供快速高效的免疫反应并且可以辨认多种抗原(身体里的毒素或外来物质)。在本研究中,作者旨在通过分析血液和组织样本来研究瘢痕瘤中的一种名为CD3+CD45RO+的特异性记忆T细胞的异常现象。来自中国上海的作者发现,瘢痕瘤疤痕中的大部分T淋巴细胞都是CD3+CD45RO+记忆T细胞,并且他们还说明了区分这种类型的细胞与另一种名为FOXP3-CD8-mT的记忆T细胞的方法。作者们还发现,在拥有多个瘢痕瘤疤痕的患者中,名为CD4+CD25highFOXP3+调节性T细胞的数量显著减少,而瘢痕瘤疤痕中的CD8+CD103+记忆T细胞的数量则明显增加。作者们总结道,瘢痕瘤疤痕中的CD45RO+记忆T细胞子集存在明显的异常现象,这可能意味着T细胞反应的调节异常可能在瘢痕瘤的疤痕形成中起着作用。还需要进一步研究。
NATURE'S FOOD.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Surgical specialties in the medical curriculum. Their pertinent and impertinent purposes
Authors: C. R. Hanlon
Journal: JAMA (1967)

It is a custom of speakers afflicted with a difficult topic to spend considerable time in analyzing the title of their troublesome assignment and follow this with a disclaimer of responsibility for the title. In adopting this custom, I might characterize my assigned title as illegitimate and immediately and steadfastly deny paternity. Alternatively, I could have diminished its tendentious character by changing it to some pleasant banality, such as, "Surgical Specialties in the Significant Sixties." Ultimately, I recognized that I must face up to the challenge. The title states quite baldly that there<i>are</i>impertinent purposes in the relation of the surgical specialties to the medical curriculum. I am charged with determining what these presumed impertinences are, stating them here publicly, and thereafter rendering judgment on those responsible for their inclusion in the curriculum—flogging them, forgiving them, or congratulating them as fancy dictates. Let me say at once that I
Phylogenesis of the Ear
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gastrointestinal Hormones
Authors: Frank P. Brooks
Journal: JAMA (1975)

ALL known gastrointestinal hormones are polypeptides rather than amines or steroids.<sup>1</sup>They fall into two groups, gastrin and cholecystokinin-pancreozymin (CCK-PZ), according to their chemical structure. Both are straight-chain peptides that share the same four amino acids at the ends of amide groups (C-terminal tetrapeptide); probably as a consequence of their structure, they act (although often in opposite directions) on the same tissues. The amide end of the molecule has all the actions of the complete hormone. The primary mission of gastrin is to stimulate gastric acid secretion, whereas CCK-PZ chiefly stimulates pancreatic secretion and contraction of the gallbladder. These hormones have a wide spectrum of additional actions. The CCK-PZ group is a series of polypeptides with similar amino acid sequences extending throughout the length of the peptide chain. Secretin, the prototype, has a helical structure; possibly as a result, virtually the entire sequence is necessary for biological activity. Secretin
ANOTHER STEP IN THE RISE OF SURGICAL PHYSIOLOGY.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prognostic relevance of early response to induction chemotherapy (IC) in locally advanced NSCLC by 18FDG positron emission tomography (PET)
Authors: C. Hoekstra, E. Smit, J. Vansteenkiste, S. Stroobants, H. V. Tinteren, P. Postmus, A. Lammertsma, O. Hoekstra
Journal: Journal of Clinical Oncology (2004)

7001 Background: In locally advanced NSCLC the performance of response monitoring after combined modality treatment (CMT) using standard CT criteria is limited. Identifying patients with a response to IC in a more reliable way at an early stage of treatment could have major clinical implications. 18FDG PET may be used to assess the effect of IC. The objective of this study was to determine the accuracy of early response measurements using 18FDG PET with respect to survival of stage IIIA-N2 NSCLC patients undergoing CMT. Methods: Consecutive stage IIIA-N2 NSCLC patients who received 3 cycles of platinum based IC were included. A dynamic PET scan was performed prior to the start of IC and after course 1 and 3. CT scan of thorax and upper abdomen was performed before and at the end of IC. PET analysis of the primary tumor was performed by Patlak graphical analysis at 10–60 minutes post injection. The mediastinal lymphnode (MLN) status was assessed visually, and analysed using Kaplan Meier plots and the logrank test (p < 0.05). Cox proportional hazard regression analysis was used to assess the prognostic value of the baseline and %change in 18FDG PET-uptake (MRglu) with respect to survival time. Results: 47 patients (33 men, 14 women, mean age 63 (range 30–81) years) were included. Median follow up is 28 months. MLN status by PET after 1 cycle of IC did not show a significant relation with survival (p=0.74). Baseline Mrglu-value together with the percentage decrease in uptake after one course was related to survival (p=0.05 and p=0.02 respectively in the combined model). The percentage decrease after 3 courses was even more predictive for survival. Conclusions: Response assessment to CMT in stage IIIA-N2 NSCLC using the %change in uptake of 18FDG with PET after 1 and 3 courses of IC is correlated with survival. No significant financial relationships to disclose.
Discovery of new adverse drug reactions. A review of the Food and Drug Administration's spontaneous reporting system
Authors: A. C. Rossi
Journal: JAMA (1984)

Recently, several studies of spontaneous reporting systems (SRSs) have reported on the published literature's role in producing first reports of new adverse drug reactions. In order to provide further information on other components of SRS, the Food and Drug Administration's SRS was examined with regard to its effectiveness and efficiency in identifying new adverse drug reactions and the form, consistency, and timeliness of its communication of new adverse drug reactions to the medical community. While there was evidence that the literature was more effective in producing first reports of new adverse drug reactions for the years compared, there was reason to conclude that FDA's SRS was capable of making a contribution to the alerting process. Moreover, direct participation by practitioners in FDA's SRS was found to be the most efficiently obtained FDA source of new adverse drug reaction reports. (<i>JAMA</i>1984;252:1030-1033)
THE MEDICAL SOCIETY OF THE DISTRICT.
Journal: JAMA (1896)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE TREATMENT OF OTITIS EXTERNA WITH ACRIFLAVINE
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Patients are more satisfied with a patient centred approach
Journal: BMJ (2001)

Thyroxine does not benefit euthyroid people with symptoms of hypothyroidism Thyroxine is no more effective than placebo in improving cognitive function and psychological wellbeing in patients with symptoms of hypothyroidism but with thyroid function tests within the normal range.In addition, thyroxine does not improve cognitive function and psychological wellbeing in healthy adults.Pollock and colleagues (p 891) conducted a randomised, double blind, placebo crossover trial on 22 patients with symptoms of hypothyroidism, but biochemically euthyroid, and 19 healthy controls.They also found that there was no significant changes in clinical measurements such as blood pressure, pulse rate, or weight during the study. Metered dose inhalers are most cost effective for asthma drugsPressurised metered dose inhalers are the most cost effective method for delivering 2 agonists and corticosteroids in patients with stable asthma.In two systematic reviews (pp 896 and 901), the National Health Technology Assessment Inhaler Review Group found no significant differences between pressurised metered dose inhalers and other inhaler devices.These included dry powder inhalers, breath actuated devices, and hydrofluoroalkane devices.Use of a spacer device did not affect the results.Since pressurised metered dose inhalers are usually the cheapest form of treatment, they should be used as first line treatment unless there are specific contraindications.