tbuckley/cabot-search huggingface dataset:
Last Call for AMA-RPS Interim Meeting
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Antioncogenes and Human Cancer
Authors: D. Carbone
Journal: Annual Review of Medicine (1993)

Multiple genetic lesions are thought to transform a normal cell into a malignant one, and both dominant and recessive genetic effects have been identified in this process. Antioncogenes (or tumor suppressor genes) act in a recessive manner, in which both maternal and paternal alleles need to be inactivated to abrogate normal function. The identification of these lesions is giving us insight into the regulatory pathways in the cell and may translate into future improvements in prevention, diagnosis, prognosis, and therapy of human cancer.
CORRESPONDENCE SCHOOLS FOR NURSES.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cardiac effects of a cocktail
Authors: L. Gould
Journal: JAMA (1971)

The hemodynamic effects of a cocktail in cardiac disease have not been previously studied, to our knowledge. Ten patients with cardiac disease and four normals underwent cardiac catheterization. Hemodynamic measurements were obtained prior to and 30 minutes after oral ingestion of 2 oz of Canadian whiskey. With alcohol, all of the patients with cardiac disease demonstrated a fall in the cardiac index and stroke index. Alcohol produced in the normals an increase in these measurements. The cardiac rate, systemic blood pressure, and pulmonary artery pressure were essentially unchanged in both groups. Small amounts of alcohol can impair cardiac function in patients with cardiac disease.
Third International Symposium: Cancer Therapy by Hyperthermia, Drugs, and Radiation
Journal: JNCI Journal of the National Cancer Institute (1979)

Journal Article Third International Symposium: Cancer Therapy by Hyperthermia, Drugs, and Radiation Get access JNCI: Journal of the National Cancer Institute, Volume 63, Issue 3, September 1979, Page 876, https://doi.org/10.1093/jnci/63.3.876-b Published: 01 September 1979
A NATIONAL QUARANTINE LAW.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Comment on “ <i>Aggregatibacter actinomycetemcomitans</i> –induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis”
Authors: Mikhail Volkov, Jacqueline Dekkers, Bruno G. Loos, Sergio Bizzarro, Thomas W. J. Huizinga, Helle A. Praetorius, René E. M. Toes, Diane van der Woude
Journal: Science Translational Medicine (2018)

The link between rheumatoid arthritis and exposure to a bacterial toxin was not found in a population of rheumatoid arthritis patients from Netherlands.
Transient oculomotor nerve palsy. Association with thiazide-induced glucose intolerance
Authors: N. R. Miller
Journal: JAMA (1978)

ISOLATED oculomotor nerve palsy frequently occurs in patients with diabetes mellitus. Most patients affected are aged 50 to 70 years and have mild adult-onset diabetes that is often under control at the time the palsy begins. The onset of diabetic oculomotor nerve palsy is usually sudden and may be associated with considerable homolateral ocular, retrobulbar, or cephalic pain. The palsy generally persists for several months before resolving spontaneously. In most instances, the pupil remains normal; however, when the pupil is paralyzed, the major differential diagnosis is between an intracranial aneurysm and diabetes.<sup>1</sup>The sudden onset of a painful, complete oculomotor nerve palsy developed in a patient while he was taking chlorothiazide. The patient's workup showed an elevated fasting blood glucose level and abnormal findings of a glucose tolerance test. After he discontinued therapy with the diuretic, the blood glucose abnormalities disappeared, and the oculomotor nerve palsy resolved. <h3>Report of</h3>
Combined Disruption of Both the MEK/ERK and the IL-6R/STAT3 Pathways Is Required To Induce Apoptosis of Multiple Myeloma Cells in the Presence of Bone Marrow Stromal Cells.
Authors: Manik Chatterjee, Thorsten Stuehmer, Pia Herrmann, Kurt Bommert, Bernd Dorken, Ralf C. Bargou
Journal: Blood (2004)
Cataract Extraction an Office Operation. Reply to Dr. T. E. Murrell by Dr. Charles W. Kollock, Charleston, S. C.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Airway function at one year: association with premorbid airway function, wheezing, and maternal smoking
Authors: C Dezateux, J Stocks, A M Wade, I Dundas, M E Fletcher
Journal: Thorax (2001)

BACKGROUND Impaired growth and development of the respiratory system during fetal and early postnatal life may have important implications for lung development and later lung health. The aim of this study was to examine the association of diminished premorbid airway function, prior wheezing, and maternal smoking with airway function at 1 year of age. METHODS Respiratory function was measured at the end of the first year in 100 of 108 healthy term infants (93%) in whom similar measurements had been undertaken prior to any respiratory illness at 8 weeks. Physician diagnosed wheezing episodes were identified retrospectively from medical records. RESULTS At 1 year specific airway conductance during end expiration (sGaw ee ; /s/kPa) was significantly diminished in those infants with prior wheezing (95% CI wheeze/no wheeze –0.76 to –0.14), mothers who smoked (95% CI smoke/no smoke –0.81 to –0.27), a family history of asthma (95% CI family history/no family history –0.62 to 0.00), or diminished premorbid sGaw ee (95% CI –0.13 to –0.43/s/kPa per unit reduction sGaw ee at 8 weeks). In a multivariate model only maternal smoking and diminished premorbid sGaw ee were independently associated with diminished sGaw ee at 1 year. CONCLUSIONS Diminished airway function at the end of the first year appears to be mediated by impaired airway development during early life as well as by exposure to maternal smoking. These findings are consistent with the hypothesis that, at a population level, diminished premorbid airway function provides the link between wheezing lower respiratory illness and diminished airway function at 1 year. Maternal smoking remains an important and avoidable cause of impaired airway development and function in infancy.
Tuberculosis in Patients with Human Immunodeficiency Virus Infection
Authors: Peter F. Barnes, Alan B. Bloch, Paul T. Davidson, Dixie E. Snider
Journal: New England Journal of Medicine (1991)

THE number of cases of tuberculosis reported annually in the United States declined steadily from 84,304 in 1953 to 22,255 in 1984.1,2 In a dramatic reversal of this trend, the number rose by 3 percent in 1986, by 5 percent to 23,495 in 1989, and by a provisional 6 percent in 1990.1 2 3 4 This unprecedented resurgence of tuberculosis is largely related to the human immunodeficiency virus (HIV) epidemic.1 2 3 Among the diseases associated with HIV infection, tuberculosis is of particular importance because it is contagious by the respiratory route, readily treatable, and potentially preventable with chemoprophylaxis. Physicians must be familiar with the . . .
CONSERVATIVE THERAPEUTICS
Authors: THOMAS ORDWAY
Journal: JAMA (1926)

Notwithstanding the advance in medical science and the great improvement in medical education during the last twenty years, it is obvious that from the standpoint of the general public medical practice is not satisfactory. During the last few years, heated and conflicting criticisms of medical education by those in positions of authority have been factors in the formation of a commission on medical education to make a thorough survey of present requirements of medical practice. A not inconsiderable number of the people, including many otherwise intelligent persons, because of dissatisfaction with medical practice, go to the so-called cults, seeking relief from physical and mental difficulties. In 1834, in a discourse on quackery, Dr. Zadok Howe pointed out the danger of the irregular practitioners whose energy at this time was devoted largely to the sale of "patent" vegetable remedies. He made interesting suggestions to check this evil, such as the diffusion
Abstract 4400: Comprehensive Open Reading Frame Mutational Analysis of the <i>RYR2-</i> Encoded Ryanodine Receptor/Calcium Channel in Patients Diagnosed Previously with Either Catecholaminergic Polymorphic Ventricular Tachycardia or Genotype Negative, Exercise-Induced Long QT Syndrome
Authors: Argelia Medeiros-Domingo, David J Tester, Michael J Ackerman
Journal: Circulation (2008)

Pathogenic mutations in the RYR2 -encoded cardiac ryanodine receptor cause type 1 catecholaminergic polymorphic ventricular tachycardia (CPVT1), a cardiac channelopathy with increased propensity for lethal ventricular dysrhythmias. Most RYR2 mutational analyses target three canonical domains encoded by &lt; 40% of the translated exons. The extent of mutations localizing outside of these domains remains unknown as RYR2 has not been examined comprehensively in most patient cohorts. Mutational analysis of all 105 RYR2 exons was performed using PCR, DHPLC, and DNA sequencing on 108 unrelated patients (57% females, 96% white, age at diagnosis 18 ± 13 years, mean QTc 424 ± 26 ms) with either an explicit referral diagnosis of CPVT (N = 60) or an initial diagnosis of exercise-induced long QT syndrome (LQTS) but with QTc &lt; 480 ms and a subsequent negative LQTS genetic test (N = 48). Two hundred healthy individuals from the Human Genetic Cell Repository were examined to assess allelic frequency for all non-synonymous variants detected. Thirty-eight (15 novel) possible CPVT1-associated mutations absent in 400 reference alleles, were detected in 44 unrelated patients (41%). Three cases (7%) had &gt;1 RYR2 mutation. Besides the 25 exons known previously to contain causative mutations, eight new mutation-containing exons were identified: 10, 12, 13, 21, 26, 40, 42, and 48. Nearly two-thirds of the CPVT1-positive patients had mutations that localized to one of only 7 exons: 8, 14, 47, 90, 93, 100, and 101. In addition, 5 (2 novel) common non-synonymous single nucleotide polymorphisms were identified. This study represents one of the largest cohorts of patients for which RYR2 was examined in its entirety. Possible CPVT1 mutations in RYR2 were identified in approximately 41% of both CPVT referrals and LQTS gene-negative patients with exercise-induced syncope and QTc &lt;480 ms. Including the eight new exons hosting mutations in this study, 33 of the 105 translated exons are now known to host possible mutations. Considering that two-thirds of CPVT1-positive cases would be discovered by selective analysis of &lt;10 exons, a tiered targeting strategy for mutation discovery may afford a more cost-effective approach to CPVT genetic testing.
CONCERNING INDEXES OF MEDICAL JOURNALS.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Special Announcement
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Policy Change
Authors: Chris Anne Raymond
Journal: JAMA (1988)

THE AMERICAN FERTILITY Society is recommending that physicians no longer use fresh semen for artificial insemination (<i>JAMA</i>1987;258:2025). The change in policy arises from concern about the potential for unwittingly transmitting human immunodeficiency virus (<i>JAMA</i>1988;259:1301). The society now recommends that all specimens be frozen and quarantined for 180 days. At the end of that period, the donor should be retested and confirmed as seronegative. The complete revised guidelines appear in the February issue of<i>Fertility and Sterility</i>.
Controlled Trial of Azathioprine and Prednisone in Chronic Renal Disease
Journal: BMJ (1971)

Patients with various forms of glomerulonephritis, but excluding those with minimal glomerular changes, were admitted to a controlled trial of a regimen which combined azathioprine in a dosage of 2·5 mg/kg/day with prednisone in a dosage of 20 mg/day (adults) or 0·5 mg/kg/day (children). Of 149 patients included, 32 of them under the age of 15, 72 were randomly allocated to the “treatment” group and 77 to the “control” group. There was no evidence of benefit from the treatment group as a whole; and the mortality was in fact higher in the treated group.
I am a 58 year old retired clinical oncologist. I took early retirement at age 55 and subsequently underwent open heart surgery, from which I have recovered. I am now anxious to return to some sort of patient care, although not in oncology. I am willing to retrain. I understand the DoH/NHS is trying to attract back retirees but I am finding it difficult to obtain specifics. Can someone point me in the right direction?
Authors: Trevor Pickersgill
Journal: BMJ (2005)

<b>www.bmjcareers.com/advicezone</b> Have a career or related problem that needs answering? Can9t find the right person to point you in the right direction? Log on to the Advice Zone for reliable medical careers advice. You can post a question or see if one of our 300 advisers has already answered a similar question. Here is a selection of questions and answers posted on the site.
FAMILY PRACTICE, A CONCEPT OR REALITY?
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Results of Surgical Therapy of Severe Stasis Ulceration of the legs
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AMALGAMATION OF MEDICAL SCHOOLS.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal