tbuckley/cabot-search huggingface dataset:
Abstract P385: My Unlimited Health Potential: Short term Effect of Participation in a Worksite Lifestyle Intervention Program on Significant Weight Loss and Eligibility Criteria for Bariatric Surgery Among High Risk Individuals
Authors: Lara L Roberson, Ehimen Aneni, Sameer Shaharyar, Ebenezer Oni, Maribeth Rouseff, Thinh Tran, Henry Guzman, Salkalp Das, Doris Brown, Joann Santiago-Charles, Teresa C Ochoa, Joseph Mora, Beatriz Castillo, Emir Veladar, Theodore Feldman, Arthur Agatston, Janisse Post, Khurram Nasir
Journal: Circulation (2014)

Background: Current recommendations support bariatric surgery among the morbidly obese as an option to mitigate future risk of cardiovascular disease, diabetes and hypertension. To date, there is little evidence on the effect of extensive lifestyle interventions among those high-risk individuals in reducing the need for such procedures. Methods: The purpose of the present study was to examine the efficacy of an intensive lifestyle workplace intervention on significant body weight and cardiovascular disease risk factors across the spectrum of obesity. Changes in BMI were measured from baseline to 12 week follow up, along with corresponding improvements in cardio-metabolic risk. In addition, the decrease in participants meeting criteria for bariatric surgery over the study period was examined. Bariatric surgery criteria were defined as BMI≥40 or BMI between 35 and 40 and at least one of the following co-morbidities: diabetes, hypertension, or high cholesterol. Results: The study population consisted of 169 individuals (49±10 years, 77% female) with BMI≥27 at baseline and complete data at follow-up. A total of 65 (39%) participants lost at least 5% of both their initial BMI and body weight. Additionally, 32% dropped an entire BMI category. Of note, 38%(18 of 48) who were classified as BMI&gt;40 were in BMI 35-39 at follow-up, respectively 37%(13 of 55) of individuals in the BMI category 35-39 successfully moved to the BMI category 30-34 at 3 months follow-up. Sixty-three participants (37% of total) initially met criteria for bariatric surgery. At 12 weeks follow-up 35% (22 of 63) of these candidates no longer qualified. Conclusions: Worksites can be effective for achieving clinically important reductions in body weight and diminish the potential need for procedures among a small proportion of morbidly obese individuals. Further follow-up is needed to ascertain whether weight loss can be sustained long-term, and if the short term gains will translate to significant improvements in cardio-metabolic risk profile.
Rudolf Magnus (1873-1927) physiology of posture
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Symbols used in the Table of Contents
Authors: Seema Sarin, Bradley Undem, Alvin Sanico, Alkis Togias, Richard Lockey, Tetsuya Ueda, Akio Niimi, Hisako Matsumoto, Masaya Takemura, Toyohiro Hirai, Masafumi Yamaguchi, Hirofumi Matsuoka, Makiko Jinnai, Shigeo Muro, Kazuo Chin, Michiaki Mishima
Journal: Journal of Allergy and Clinical Immunology (2006)
Biomarkers for Assessing Human Female Reproductive Health, An Interdisciplinary Approach
Authors: Bill L. Lasley, James W. Overstreet
Journal: Environmental Health Perspectives (1998)

Identification of environmental hazards to reproductive health and characterization of the adverse outcomes necessitate a multidisciplinary approach.Epidemiologic studies are required for the identification of adverse health effects in human populations and then to confirm that specific exposures are responsible.Clinical studies are required to develop assays for reproductive biomarkers and to validate these assays prior to their application in the field.Assays for field use must be formatted and streamlined for large-scale applications and, whenever possible, computer algorithms should be developed to interpret biomarker data.Appropriate animal models must be identified, biomarker assays validated for that model, and animal experiments conducted to identify the mode of action and target organ of a putative reproductive toxicant.Finally, in vitro studies at the level of the cell and cell organelle are essential for mechanisms of toxicity to be clearly identified and understood.In this article we describe the interdisciplinary approach that we have developed for study of the effects of environmental agents on female reproductive functions.This effort requires specific skills of toxicologists, epidemiologists, physicians, biochemists, and physiologists.
ERYTHEMA NODOSUM
Authors: J. D. Howe
Journal: BMJ (1921)

A LMzw Njs I. z)cALim A Ivy M., aged 12, was seen on September 19th with well- inarke(d niodes on both shins and a sore throat.TlThe nodes later also appeared on the extensor aspect of the arms and Joint pains were present.Ier attackwas much less severe, and she was well in about a fortnight.Phyllis M., aged 17, also developed the disease; she was seen first on October 3rd.The crop uf nodes was conifined to the shins, anid she complained of sore throat.Her attack was less severe thasn in the other two cases, the period of illness being about a fortniiglht.
US abundance of physicians and international health
Authors: R. E. Pust
Journal: JAMA (1984)

American clinicians with careers encompassing both Third World and underserved American populations would benefit both regions and bring new perspectives to foreign policy and domestic health care problems. Application of the parallel concepts of Community-Oriented Primary Care and Health for All should help contain costs and extend access to appropriate clinical care both in the United States and abroad. As American physicians weigh their short- or long-term career options in the post—Graduate Medical Education National Advisory Council era, there is an urgent need both for a specific US policy on international health and for new partnerships to facilitate careers spanning domestic and Third World areas of need. (<i>JAMA</i>1984;252:385-388)
The Development of Obesity in Young U.S. Adults, 1981–1998
Journal: Annals of Internal Medicine (2002)

Summaries for Patients18 June 2002The Development of Obesity in Young U.S. Adults, 1981–1998Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-136-12-200206180-00001 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Americans are becoming overweight at an alarming rate. In 1960, about 31% of Americans were overweight and 13% were obese. By 1999, 35% of Americans were overweight and 26% were obese. Body mass index (BMI) is a way to measure whether a person is of appropriate weight. BMI is calculated by dividing a person's weight in kilograms by the square of his or her height in meters (BMI = weight in kilograms/height in meters 2). An appropriate BMI is between 18.5 kg/m2 and 25 kg/m2. People with BMIs ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “The Natural History of the Development of Obesity in a Cohort of Young U.S. Adults between 1981 and 1998.” It is in the 18 June 2002 issue of Annals of Internal Medicine (volume 136, pages 857-864). The authors are KM McTigue, JM Garrett, and BM Popkin.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe Natural History of the Development of Obesity in a Cohort of Young U.S. Adults between 1981 and 1998 Kathleen M. McTigue , Joanne M. Garrett , and Barry M. Popkin Metrics 18 June 2002Volume 136, Issue 12Page: I-24KeywordsBirthBody mass indexHispanic peopleLongitudinal studiesObesityOverweightPrevention, policy, and public healthPrimary hypertensionWeight gainYoung adults ePublished: 18 June 2002 Issue Published: 18 June 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Omission and Error
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
成人特应性皮炎与心血管疾病及2型糖尿病的关联:一项系统综述与元分析
Authors: J.P. Thyssen, A.-S. Halling-Overgaard, Y.M.F. Andersen, G. Gislason, L. Skov, A. Egeberg
Journal: British Journal of Dermatology (2018)

特应性皮肤炎(AD)是儿童中的一种常见湿疹,在有些人身上会一直持续到成人阶段。有人认为它与其他疾病(被称为“并存病”)有关联,但是一项旨在探索它是否与2型糖尿病和心血管疾病(CVD,一组疾病/病症,包括中风、高血压、心肌梗塞、心绞痛、冠状动脉疾病和心力衰竭)有关联的研究却得出了不一致的结果。这项来自丹麦的研究分析了16项相关性最高的研究,比较了有AD和无AD的成人患者患CVD和糖尿病的风险。未发现AD与2型糖尿病、高血压、中风或心肌梗塞有关联,但发现它与心绞痛有关联,不过这项发现仅基于四项研究。作者得出的结论是,虽然在部分人群中,某些因素确实更有可能会提高患CVD的风险(如吸烟和肥胖),但是AD本身不太可能是CVD的风险因素.
Regional Enteritis
Authors: S. Power
Journal: BMJ (1938)

<h3>Abstract</h3> <b>Objective</b>: To assess effect of unemployment and early retirement on mortality in a group of middle aged British men. <b>Design</b>: Prospective cohort study (British Regional Heart Study). Five years after initial screening, information on employment experience was obtained with a postal questionnaire. <b>Setting</b>: One general practice in each of 24 towns in Britain. <b>Subjects</b>: 6191 men aged 40-59 who had been continuously employed for at least five years before initial screening in 1978-80: 1779 experienced some unemployment or retired during the five years after screening, and 4412 remained continuously employed. <b>Main outcome measure</b>: Mortality during 5.5 years after postal questionnaire. <b>Results</b>: Men who experienced unemployment in the five years after initial screening were twice as likely to die during the following 5.5 years as men who remained continuously employed (relative risk 2.13 (95% confidence interval 1.71 to 2.65). After adjustment for socioeconomic variables (town and social class), health related behaviour (smoking, alcohol consumption, and body weight), and health indicators (recall of doctor diagnoses) that had been assessed at initial screening the relative risk was slightly reduced, to 1.95 (1.57 to 2.43). Even men who retired early for reasons other than illness and who appeared to be relatively advantaged and healthy had a significantly increased risk of mortality compared with men who remained continuously employed (relative risk 1.87 (1.35 to 2.60)). The increased risk of mortality from cancer was similar to that of mortality from cardiovascular disease (adjusted relative risk 2.07 and 2.13 respectively). <b>Conclusions</b>: In this group of stably employed middle aged men loss of employment was associated with an increased risk of mortality even after adjustment for background variables, suggesting a causal effect. The effect was non-specific, however, with the increased mortality involving both cancer and cardiovascular disease.
Empire Rheumatism Council: Seventeenth Annual Report
Journal: Annals of the Rheumatic Diseases (1954)

A. Henly left to take up another appointment.His final report on his tenure of the "Roche Fellowship in Biochemistry" described the results obtained during clinical trials of ACTH, cortisone, and other steroid substances.The findings in general were consistent with the conclusion that such changes in steroid metabolism as were found were the results of metabolic abnormalities associated with the disease process and that primary adrenal dysfunction was not a causative factor in the development of rheumatoid arthritis.
Asbestos-like fibers in Duluth water supply. Relation to cancer mortality
Authors: T. J. Masson
Journal: JAMA (1974)

Asbestos-like fibers in industrial waste first entered the water supply of Duluth in 1955. In the next 14 years, no carcinogenic effect was apparent in the patterns of cancer mortality among persons of all ages, nor among children. The period of observation is short relative to the latent period for occupationally induced carcinogenesis from asbestos. (<i>JAMA</i>228:1019-1020, 1974)
Fish Zona Radiata (Eggshell) Protein: A Sensitive Biomarker for Environmental Estrogens
Authors: Augustine Arukwe, Frank R. Knudsen, Anders Goksoyr
Journal: Environmental Health Perspectives (1997)

Environmental estrogens have recently caused great concern because of their ability to mimic natural hormones and influence vital endocrine functions in humans and wildlife. The induction of vitellogenin (Vtg) synthesis by environmental estrogens in viviparous vertebrates has been proposed as an effective and sensitive biomarker of estrogenicity. Immunochemical analysis of plasma from Atlantic salmon (Salmo salar) exposed to 4-nonylphenol (NP) or to effluent from oil refinery treatment plant (ORTP), shows that NP and ORTP effluent induces Vtg and zona radiata proteins (Zrp) in a dose-dependent manner. However, Zrp-beta cross-reactive proteins are more responsive than Zrp-alpha, Zrp-gamma, and Vtg. The sensitivity of Zrp induction points to the zona radiata proteins as alternate biomarkers of estrogenicity.
Right-Sided Heart
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Urinary Phosphate Excretion in Hypoparathyroidism
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Recognizing symptom complex prevalence in an outpatient oncology patient population: A performance improvement project
Authors: E. McCreary, J. D'Olimpio, C. Meci
Journal: Journal of Clinical Oncology (2004)

8219 Background: Poly-symptomatology is a frequently observed problem in the treatment of cancer patients in both the outpatient and inpatient setting, frequently leading to poor compliance with therapy and diminished quality of life. Symptom complexes are not translated into routine clinical charts/data bases because patients frequently do not relate these symptoms unless prompted. Previous Performance Improvement Projects have demonstrated the need to capture relevant clinical information to enhance patient care. Methods: 8 common symptoms were formatted into a single questionnaire using a 0–10 analogue scale and given to ambulatory oncology patients to complete anonymously in the waiting room. Pain, nausea/vomiting, fatigue, depression, shortness of breath, numbness/tingling, constipation and diarrhea were rated on a scale of 0–10 in 2 domains: average and current symptom intensity. Each questionnaire was then reviewed by 3 observers who "voted" on the accuracy and completeness of the data. Questionnaires were discarded if not completed or legible. Patient confidentiality was not at risk since no identifiers were used. Results: 132 patients were screened and 401 symptoms were rated, ave 3.2 symptoms per patient.27 patients had no symptoms.27 patients had only pain/ fatigue/ depression as a complex.13 patients had only nausea/ vomiting/constipation/diarrhea as a complex.33 patients had numbness/tingling/constipation/diarrhea as a complex. Average symptom severity was 3.8/10. Conclusions: The discovery that patients have specific complexes of symptoms that are not routinely captured in normal day to day outpatient management charting indicated a need to monitor the incidence of these symptoms as they relate to quality of life. In this way, busy clinicians can utilize PI initiatives to improve patient care in vulnerable cancer populations. No significant financial relationships to disclose.
MEDICAL COLLEGE ENDOWMENTS.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INFANTILE TUBERCULOSIS.
Authors: LOUIS FISCHER
Journal: JAMA (1898)

A very large number of tuberculous children seen in the course of the last ten years is my excuse for attempting to bring this subject before your honorable body for discussion. This subject is handled in a masterly manner in the text-book of Professor Baginsky, and I shall therefore follow his classification. There is certainly a decided relationship existing between scrofulosis and tuberculosis, and thus most distinguished pediatrists believe the two diseases to be identical with one another. In fact, in studying the large number of cases of scrofulosis seen by me, it is more and more apparent that this disease is the stepping-stone to tuberculosis, and that one is the result of the other. In former years the textbooks speak of the scrofulosis diathesis, and this latter condition we today recognize as the pre-tuberculous condition. The infant at birth that is put on an improper food is certainly a
Chloroquine-Resistant Falciparum Malaria
Authors: W. D. Tigertt
Journal: JAMA (1967)

<h3>To the Editor:—</h3> Dr. Shookoff's timely letter brings up a question familiar to all physicians: Which of two courses of action is least hazardous to the patient? In the present instance, when faced with possible chloroquine-refractory malaria, a potentially and sometimes rapidly fatal illness, should the physician risk the time required to evaluate the response to chloroquine or should he employ a known effective drug, quinine, and accept possible toxicity? Dr. Shookoff reminds us that quinine may produce an acute hemolytic episode. While this statement appears frequently in print, there is no agreement amongst malariologists as to the frequency with which quinine is the actual precipitating factor. He advocates a trial with chloroquine, "unless the patient is in a precarious condition," and evaluation of the response over a 24- to 48-hour period. The problem here lies in the notorious lack of ability to truly evaluate the status of the falciparum