Risks for Bleeding in Patients with Pulmonary Embolism Treated with Thrombolytic Agents
Authors: Paul D. Stein
Journal: Annals of Internal Medicine (1995)

Letters15 April 1995Risks for Bleeding in Patients with Pulmonary Embolism Treated with Thrombolytic AgentsPaul D. Stein, Russell D. Hull, and Gary RaskobPaul D. SteinUniversity of California, San Diego, Medical Center, San Diego, CA 92103-8372. Department of Veterans Affairs Medical Center, New Orleans, LA 70146. Merrithew Memorial Hospital, Martinez, CA 94553. Union Hospital, Lynn, MA 01904. Henry Ford Heart and Vascular Institute, Detroit, MI 48202-2691.Search for more papers by this author, Russell D. HullUniversity of California, San Diego, Medical Center, San Diego, CA 92103-8372. Department of Veterans Affairs Medical Center, New Orleans, LA 70146. Merrithew Memorial Hospital, Martinez, CA 94553. Union Hospital, Lynn, MA 01904. Henry Ford Heart and Vascular Institute, Detroit, MI 48202-2691.Search for more papers by this author, and Gary RaskobUniversity of California, San Diego, Medical Center, San Diego, CA 92103-8372. Department of Veterans Affairs Medical Center, New Orleans, LA 70146. Merrithew Memorial Hospital, Martinez, CA 94553. Union Hospital, Lynn, MA 01904. Henry Ford Heart and Vascular Institute, Detroit, MI 48202-2691.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-122-8-199504150-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We appreciate the thoughtful letters about our article [1]. Although a difference of opinion appears to exist, our article may have been misinterpreted. We did not imply that we favor a broader use of thrombolytic drugs for patients with acute pulmonary embolism. Our purpose was to assess the relative risks of thrombolytic therapy administered on the basis of an invasive compared with a noninvasive diagnosis. The physician must determine the indications for thrombolytic therapy.The indications that we use, hypotension or hypoxia while the patient is receiving high doses of oxygen or echocardiographic evidence of right ventricular failure, ...References1. Stein PD, Hull RD, Raskob G. Risks for major bleeding from thrombolytic therapy in patients with acute pulmonary embolism. Consideration of invasive management. Ann Intern Med. 1994; 121:313-7. Google Scholar2. Stein PD, Athanasoulis C, Alavi A, Greenspan RH, Hales CA, Saltzman HA, et al. Complications and validity of pulmonary angiography in acute pulmonary embolism. Circulation. 1992; 85:462-9. Google Scholar Author, Article, and Disclosure InformationAffiliations: University of California, San Diego, Medical Center, San Diego, CA 92103-8372. Department of Veterans Affairs Medical Center, New Orleans, LA 70146. Merrithew Memorial Hospital, Martinez, CA 94553. Union Hospital, Lynn, MA 01904. Henry Ford Heart and Vascular Institute, Detroit, MI 48202-2691. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThrombolytic Therapy for Acute Pulmonaqy Embolism: Can Mortality Be Decreased? 15 April 1995Volume 122, Issue 8Page: 630-632KeywordsAngiographyBloodEmbolectomyHemorrhagePatient advocacyPulmonary embolismRelative riskRenal diseasesRisk managementVeins ePublished: 15 August 2000 Issue Published: 15 April 1995 Copyright & PermissionsCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...