tbuckley/cabot-search huggingface dataset:
Parathyroid Cysts
Authors: Jody Ginsberg
Journal: JAMA (1978)

Two patients had asymptomatic neck masses that proved to be cystic. In each case, the lesions resolved after needle aspiration of 25 ml of clear, colorless fluid. Serum thyroid indexes and calcium levels were normal. Cyst fluid parathyroid hormone (PTH) levels were 0.56 and 1.50 ng/ml, respectively. The serum PTH level in case 1, determined at the same time, was less than 0.05 ng/ml (normal, 0 to 0.3 ng/ml). These observations indicate that (1) clear, colorless cyst fluid may indicate a parathyroid cyst, (2) serum and cyst fluid PTH levels can confirm the diagnosis, and (3) needle aspiration may be appropriate therapy for the benign, nonfunctioning parathyroid cyst. (<i>JAMA</i>240:1506-1507, 1978)
THE SHEPPARD-TOWNER BILL
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Inflammation, Cholesterol Levels, and Risk of Mortality Among Patients Receiving Dialysis
Authors: Kamyar Kalantar-Zadeh, Stefan D Anker
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"Cooling-Off" vs Immediate Revascularization for Patients With Acute Coronary Syndromes—Reply
Authors: Franz-Josef Neumann, Adnan Kastrati, Albert Schömig
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Electron-beam computed tomography permits accurate quantitation of long-term changes in myocardial perfusion: a follow-up study in comparison to intracoronary doppler ultrasound Stefan M�hlenkamp, Amir Lerman, Thomas R. Behrenbeck, Lilach O. Lerman, Patricia E. Lund, Patrick F. Sheedy, II, Erik L. Ritman. Mayo Clinic and Foundation, Dept of Physiology and Biophysics, Rochester, MN
Journal: Journal of the American College of Cardiology (2001)
In the Spotlight: Health Information Systems
Authors: Niilo Saranummi
Journal: IEEE Reviews in Biomedical Engineering (2012)

Healthcare systems deal with only a part of the health continuum as they are organized to diagnose and treat patients. The Connected Health paradigm covers the continuum and includes the healthy and at risk individuals and chronically ill patients. The current system has been characterized as health profession centric; patients seek medical care which is delivered by healthcare professionals. In Connected Health, individuals are equal partners with healthcare professionals and take part in managing their health, wellness and care. Connected Health can be construed as being made up of one vertical layer providing privacy, security and interoperability services so that the users are able to use and trust the services and of five interacting horizontal layers as follows. The bottom layer houses the communications infrastructure, data stores (e.g. EHRs and PHRs) etc. The second layer health IT applications that enable and support the services on the third layer. The third layer is the one where health services are delivered. These cover the health continuum from end-to-end. The services span, e.g., wellness, self-management, retail clinics, policlinics, surgical operations and intensive care. The users see these as one integrated and accessible bundle. The fourth layer deals with reimbursement of health services. Providers can be paid on fee for service, capitation or pay for performance basis or a combination of these. The fifth layer sets the laws, regulations and policies that govern how health services are delivered and consumed. Health systems are already costly. Changes in demographics, our lifestyles and innovations in life sciences, medicine and technology are enabling new and improved care for all, which adds pressure to increase health expenditures.
Effect of the Centers for Medicare &amp; Medicaid Services Policy About Deep Sedation on Use of Propofol
Authors: Douglas K. Rex
Journal: Annals of Internal Medicine (2011)

Letters20 September 2011Effect of the Centers for Medicare & Medicaid Services Policy About Deep Sedation on Use of PropofolDouglas K. Rex, MDDouglas K. Rex, MDFrom Indiana University Hospital, Indianapolis, IN 46202.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-155-6-201109200-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Endoscopists have traditionally administered opioids and benzodiazepines for sedation—either themselves or by assigning the task to a registered nurse under their supervision—with an excellent published safety record (1). Many state nursing boards allow the use of this model, including for administration of propofol. There is extensive evidence that this model has been used with even better safety for administration of propofol titrated to moderate as well as deep sedation (1). Dr. Hannenberg cites no evidence to the contrary; rather, he cites the 20-year-old package insert for propofol and the opinions of The Institute for Safe Medication Practices and ...References1. Rex DK. Effect of the Centers for Medicare & Medicaid Services policy about deep sedation on use of propofol. Ann Intern Med. 2011;154:622-6. [PMID: 21536938] LinkGoogle Scholar2. American Society of Anesthesiologists Task Force on Sedation and Analgesia by Non-Anesthesiologists. Practice guidelines for sedation and analgesia by non-anesthesiologists. Anesthesiology. 2002;96:1004-17. [PMID: 11964611] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Indiana University Hospital, Indianapolis, IN 46202.Disclosures: None disclosed. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-2863. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEffect of the Centers for Medicare & Medicaid Services Policy About Deep Sedation on Use of Propofol Douglas K. Rex Effect of the Centers for Medicare & Medicaid Services Policy About Deep Sedation on Use of Propofol Alexander A. Hannenberg Metrics 20 September 2011Volume 155, Issue 6Page: 405KeywordsAnesthesiaConflicts of interestGastroenterology and hepatologyMedicareNursesOpioidsSafetySedation ePublished: 20 September 2011 Issue Published: 20 September 2011 CopyrightCopyright © 2011 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
Neurology
Authors: Robert J. Joynt
Journal: JAMA (1991)

The role of neurologists in diagnosing and treating diseases of the nervous system also affords an opportunity to learn about the function of the nervous system. The advent of new imaging techniques has greatly expanded this opportunity. Precise localization of lesions by magnetic resonance imaging and delineation of disturbed function of certain brain areas by positron emission tomography have led to new ideas on brain-behavior linkages and to novel hypotheses about neural organization. One group of investigators using some of these techniques, along with extensive neuropsychological testing, has shown that specific types of memory may have quite diverse localization in the brain.<sup>1</sup>This alters the traditional view that memory is largely stored in one neural system. They also propose that neural processing takes place in convergence zones. Thus, there are a series of regions with information moving forward and backward so that final representation in the convergence zone is
Response to Letter Regarding Article, “Advanced Glycation End Products Accumulate in Vascular Smooth Muscle and Modify Vascular but Not Ventricular Properties in Elderly Hypertensive Canines”
Authors: Brian P. Shapiro, Theophilus E. Owan, Selma F. Mohammed, Donna M. Meyer, Lisa D. Mills, Margaret M. Redfield, Casper G. Schalkwijk
Journal: Circulation (2009)

Smooth Muscle and Modify Vascular but Not Ventricular Properties in Elderly Hypertensive Canines"We thank Dr Hartog and colleagues for their interest in our study 1 and agree with their conclusion that other advanced glycation end product (AGE) structures could be present in vascular (or ventricular) tissue.As acknowledged in the limitations section of the discussion, "We did not assess the presence of other AGE structures . .." (p 1008).We would have liked to have measured other AGE structures but were unable to find reliable methodologies to do so, and we emphasized that, "although CML [N ⑀ -(carboxymethyl)lysine] is commonly used as a marker of AGE accumulation, the relationship of CML content to that of other AGEs and differences in tissue deposition of CML and other AGEs throughout the body are poorly defined" (p 1008) and cited a review of the technical difficulties in assessing different AGE structures in vivo. 2 We further agree that despite our findings, this area is deserving of further study, as outlined in the final sentence of the article: "Furthermore, the potential for AGE-modifying therapies to improve vascular or ventricular properties deserves further study but should include careful attention to potential changes in vascular size.
Chirurg, Berlin
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Repair of Tetralogy of Fallot in Neonates and Young Infants
Authors: Frank A. Pigula, Philipe N. Khalil, John E. Mayer, Pedro J. del Nido, Richard A. Jonas
Journal: Circulation (1999)

Background —The timing of repair of tetralogy of Fallot (TOF) remains controversial. Advantages to early complete repair include removal of right ventricular outflow tract obstruction, alleviation of systemic hypoxia, and avoidance of palliation with an arteriopulmonary shunt. Methods and Results —This is a retrospective review of 99 children with TOF pulmonary stenosis (TOF/PS) or TOF pulmonary atresia (TOF/PA) who were &lt;90 days of age undergoing early complete repair. Fifty-nine were prostaglandin E dependent, and 91% of neonates were symptomatic at the time of repair. Univariate and multivariate analyses of patient characteristics, anatomic features, and operative management showed the diagnosis of TOF/PA and smaller body surface area to be the only independent risk factors for death. Early mortality was 3% (3 of 99), and actuarial survival rates were 94% at 1 year and 91.6% at 5 years. Freedom from catheterization was 86% at 1 year and 73% at 5 years. Patients repaired for TOF/PA had a significantly lower freedom from reoperation than did those repaired for TOF/PS. Conclusions —Early complete TOF repair can be accomplished with a low mortality. Children with TOF/PA repaired had a lower freedom from reoperation that did those with TOF/PS. Longer follow-up, with emphasis on arrhythmias and right ventricular function, is required to define the long-term benefits of early repair.
Diastolic dysfunction and inappropriate left ventricular mass Giovanni de Simone, Maurizio Galderisi, Vittorio Palmieri, Richard B. Devereux, Marcello Chinali, Carmela Romano, Aldo Celentano. Dprt Clin &amp; Experim Med, Federico II University Hospital, Naples, Italy, Weill Medical College of Cornell University, New York, NY
Journal: Journal of the American College of Cardiology (2001)
Role of HER2 status in the treatment of brain metastases arising from breast cancer by stereotactic radiosurgery.
Authors: Y. Novik, S. Kunnakkat, B. Donahue, S. Rush, J. Golfinos, E. Parker, A. Narayana
Journal: Journal of Clinical Oncology (2011)

117 Background: Overexpression of human epidermal growth factor receptor-2 (HER2) in breast cancer has been shown to be an independent risk factor of development of brain metastases (BM). However, the role of HER2 on the radiosensitivity of BM remains controversial. We investigated the efficacy of single fraction stereotactic radiosurgery (SRS) in the treatment of limited BM from breast cancer, based on the HER2 status. Methods: From 2004 to 2010, 57 patients with limited BM were treated with SRS using Leksell Gamma-Knife to a median dose of 20 Gy (range 12-20 Gy) prescribed to the 50% isodose line. The median number of lesions treated were 2 (range 1-7) and the median tumor volume was 92.8 mm 3 (range 3.4 -793.7 mm 3 ). There were 27 HER2 positive patients, with 32 ER positive and 22 PR positive patients. Six patients were triple negative. ER/PR information was not available for 4 patients. Overexpression of HER2 was defined as HER2 +++ by immunohistochemistry using the DAKO HercepTest or fluorescent in situ hybridization (FISH) analysis. Time to local recurrence, time to development of new brain metastases, progression-free survival (PFS), and overall survival (OS) were assessed from the date of SRS. Results: With a median follow-up of 11 months (range 1-66 months), 12 patients developed recurrence at the previously treated site (9 HER2 positive patients) and 30 developed new brain metastases (16 HER2 positive patients) The median PFS and OS for all patients were 8 and 16 months respectively. The median PFS for HER2 positive patients compared to HER2 negative patients were 7 and 11 months, respectively (p=0.352). HER2 positive patients had a median OS of 20 months, compared to 14 months in HER2 negative patients (p=0.086). Five patients went on to develop leptomeningeal disease, all of whom were HER2 positive. Conclusions: HER2 overexpression does not increase the risk of recurrence at the site of treatment or appearance of new BM. It does not affect PFS or OS following SRS. However, it remains a risk factor for the development of leptomeningeal disease.
Epilepsia partialis continua
Authors: D. A. Johnson
Journal: JAMA (1969)

A case of epilepsia partialis continua was caused by a subdural hematoma. Muscular contractions occurred primarily in the abdominal region. In this instance, the etiology of the syndrome is unique, and the primary involvement of the abdominal musculature is remarkable. Recent neurophysiological studies have shown the abdominal muscles to be separately represented in the cerebral cortex and to have a specific descending pathway in the spinal cord. The case reported here may be the clinical expression of activity in such a neural pathway.
Basis for a National Reclamation Plan by Special Committee to Study Health and Environmental Effects of Increased Coal Production.
Authors: H Dettmann, Anthony Dvorak, Douglas Grahn, Jerome Harper, James Lafevers, R Miller, Richard Olsen, Stephen O'connor, Jeffrey Schubert, Ralph Carter, Ray Hinchman, Donald Johnson, Andrew Sobek, Stanley Zellmer
Journal: Environmental Health Perspectives (1979)

The goal of the President's National Energy Plan to produce 1.25 billion tons of coal by 1985 may be achieved, but new legislation constraints and start-up delays may result in a production loss of 200-300 million tons.Well directed research to define the environmental consequence ofincreased coal production is underway, but it tends to be fragmented and ill coordinated.A national reclamation plan based on an achievable NEP must be developed that schedules, prioritizes, and
Dermatology
Authors: E. Dorinda Shelley
Journal: JAMA (1985)

Since 1975, when the first edition of this prestigious text appeared, many things have happened in dermatology, including the death of Donald M. Pillsbury, MD (1902-1980), the original senior author and editor. His distinguished collaborators (Dr Moschella is president-elect of the American Academy of Dermatology; Dr Hurley is the immediate past-president of both the American Board of Dermatology and the American Dermatologic Association) have successfully continued the spirit of the earlier edition while incorporating the important therapeutic advances of the late 1970s and early 1980s— psoralen-ultraviolet A (PUVA), lasers, retinoids, and antifungals. The basic organization has been retained, despite the substitution of many new chapters and the near doubling of the number of contributors (from 43 to 78). This vast book provides a sea of treasures for those willing to wade through its ponderous surf and dive for the pearls. Dermatologists should keep it handy as a standard office reference,
Klinische Electrokardiographie: Lehrbuch für Studierende und Ärzte
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Variegate porphyria in New England
Authors: J. E. Muhlbauer
Journal: JAMA (1982)

Variegate porphyria (VP) is an autosomal dominant disease characterized in adults by mechanical fragility and blistering of sun-exposed skin or acute visceral and neurological manifestations. The laboratory diagnosis of VP depends on a search for high levels of coproporphyrin and protoporphyrin in the feces. Variegate porphyria has been infrequently diagnosed in the United States. In this study of five New England families with VP, there were nine manifest, six latent, and six questionable cases among 40 individualsstudied. This report reviews the diagnostic approach to and treatment of affected individuals and their families. (<i>JAMA</i>1982;247:3095-3102)
Disseminated visceral Kaposi's sarcoma. Appearance after human renal homograft operation
Authors: J. H. Siegel
Journal: JAMA (1969)

A rare neoplasm, disseminated visceral Kaposi's sarcoma, appeared rapidly during the late rejection of a homograft kidney in a 35-year-old Negro woman. No evidence of tumor was present in the recipient prior to transplantation, and postmortem examination of the donor also revealed no neoplasia. Some features of Kaposi's sarcoma suggest its similarity to neoplasms of the Burkitt's type. It appears possible that immunosuppressant therapy may have permitted the development of this tumor in a transplant recipient.