tbuckley/cabot-search huggingface dataset:
Plague
Authors: Chris L. Mengis
Journal: New England Journal of Medicine (1962)

THE following awesome cases are reported as a reminder to physicians the country over that the plague is still present, still as virulent as ever and a threat with grave implications if it bursts its bounds, either in normal times or in times of chaos.Case ReportsCase 1. S.D., a 38-year-old sawmill worker from Pecos, New Mexico, was admitted to St. Vincent Hospital, Santa Fe, New Mexico, on June 28, 1961. He had suddenly become very ill 4 days previously, noting a feeling of a weight in the left side of the chest, which hurt him when he breathed . . .
Surgery is Beneficial
Journal: JAMA (1976)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Papilloma virus and cervical dysplasia
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
An uncontrolled phase II study evaluating anti-tumor efficacy and safety of ortataxel (BAY 59–8862) in patients with taxane-resistant non-small cell lung cancer
Authors: J. S. Gurtler, J. Von Pawel, C. H. Spiridonidis, F. Grossi, J. L. Larriba, M. Moscovici, E. Markovitz, D. Voliotis, M. Gottfried
Journal: Journal of Clinical Oncology (2004)

7136
Neurology
Authors: William K. Jordan, H. Houston Merritt
Journal: New England Journal of Medicine (1956)

AS in other branches of medical science, the volume of the neurologic literature has increased with each succeeding postwar year, thereby making a comprehensive review difficult. A large number of American and foreign journals and monographs have been culled in preparation of this article, and an effort has been made to select for presentation material that we consider of particular interest and usefulness to the readers of this journal. Advances in the fields of neurophysiology, vascular disease of the brain, epilepsy, muscle disorders, headache and Wilson's disease, as well as in several miscellaneous areas, are described.Anatomy and PhysiologyExperimental . . .
Miles
Authors: William M. Tierney
Journal: JAMA (1985)

I grin at the thought of how my habit of putting several miles of road beneath my feet every couple of days must appear to others, especially now as I pull on a pair of running shorts and a light jersey to face the first freezing weather of the winter season. Under a gray sky promising snow, I face into the wind as it whispers and growls across the Indiana farmland and turn on to a deserted country road. In reality, I run in a cloud of memories of failures, of lost lives and abandoned hopes. As I run, I remember too well... I remember Bradley, a young leukemic patient who had failed all standard and experimental chemotherapy, whose parents had lost their only other child to another malignancy, hating having her die in the confines of a sterile hospital, now only wanting their hopelessly ill son to die at
TESTIMONY IN RAPE CASES.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Stat Bite: NCI Research Grants
Journal: JNCI Journal of the National Cancer Institute (1995)

Stat Bite : NCI Research Grants Get access JNCI: Journal of the National Cancer Institute, Volume 87, Issue 18, 20 September 1995, Page 1353, https://doi.org/10.1093/jnci/87.18.1353 Published: 20 September 1995
Influences of pre- and postnatal nutritional exposures on vascular/endocrine systems in animals.
Authors: J J Hoet, S Ozanne, B Reusens
Journal: Environmental Health Perspectives (2000)

Human epidemiological and animal studies have revealed the long-term effects of malnutrition during gestation and early life on the health of the offspring. The aim of the current review is to survey the different means of achieving fetal malnutrition and its consequences, mainly in animals, and to identify key areas in which to direct future research. We address the impact of various models of a maternal protein-restricted diet and global maternal caloric restriction (either through the reduction of nutrient supply or through mechanic devices), the influence of maternal diabetes, and other maternal causes of fetal damage (maternal infections and toxic food components). More specifically, we enumerate data on how the different insults at different prenatal and early postnatal periods affect and program the development and the function of organs involved in diabetes, hypertension, and cardiovascular disease. Particular emphasis is given to the endocrine pancreas, but insulin-sensitive tissues, kidneys, and vasculature are also analyzed. Where available, the protective effects of maternal food supplementation for fetal organ development and function are discussed. Specific attention is paid to the amino acids profile, and the preventive role of taurine is discussed. Tentative indications about critical time windows for fetal development under different deleterious conditions are presented whenever possible. We also discuss future research and intervention.
Highlights
Authors: Howard Bauchner, C Wayant, J Scott, M Vassar, Rafael Campo, Mark Doty
Journal: JAMA (2018)

Hypertension as a Global ChallengeTwo special cover illustrations were created to bridge the concepts of the systemic nature of hypertension in the individual and the global nature of hypertension as a public health issue. Research Inorganic Nitrite for Heart Failure 1764The conversion of inorganic nitrite to nitric oxide is facilitated during exercise.In a randomized trial of 105 patients who had heart failure with preserved ejection fraction, Borlaug and colleagues found that administration of inhaled inorganic nitrite for 4 weeks, compared with placebo, did not result in signifi cant improvement in exercise capacity.
William Charles Wells (1757-1817) South Carolinian Tory
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
President's report to the house of delegates
Authors: J. Z. Appel
Journal: JAMA (1966)

Before I begin my formal report to you, the members of this House of Delegates, I must pay tribute to the greatest staff of employees that any organization in the world has. Of course I refer to the some 900 employees of the AMA. Until you work with them as closely as the President of the AMA must, you do not truly appreciate the dedication and devotion with which they serve us thru AMA, and thru this service, the people of America. It would be unfair to single out by name any of this loyal group. Dr. Blasingame please convey to each and every one of your staff my most sincere appreciation for the help they have given me and the job they are doing for the AMA. One year ago I stood before the 1965 House of Delegates of the American Medical Association and presented to the House and
Acute renal failure and transient hypercalcemia in idiopathic rhabdomyolysis
Authors: C. D. Leonard
Journal: JAMA (1970)

Acute renal failure in association with idiopathic rhabdomyolysis developed in a 29-year-old man. Symptomatic hypercalcemia occurred during the diuretic period and was accompanied by hypercalciuria, elevated serum alkaline phosphatase level, decreased tubular reabsorption of phosphate, and an increased serum parathyroid hormone level. Transient hyperparathyroidism is suggested as the primary mechanism responsible for this unusual complication of acute renal failure and physicians are alerted to this potential hazard.
Directly observed therapy for hepatitis C with sofosbuvir/ velpatasvir alongside opioid substitution as a tailored microelimination strategy in PWIDs with a high risk of non-adherence - real-world data from Vienna, Austria
Authors: Caroline Schmidbauer, Raphael Schubert, Angelika Schütz, Cornelia Schwanke, Enisa Gutic, Roxana Pirker, Tobias Lang, Thomas Reiberger, Hans Haltmayer, Michael Gschwantler
Journal: Journal of Hepatology (2020)
Statistical analysis of Clewell et al. PBPK model of trichloroethylene kinetics.
Authors: F Y Bois
Journal: Environmental Health Perspectives (2000)

A physiologically based pharmacokinetic model for trichloroethylene (TCE) in rodents and humans was calibrated with published toxicokinetic data sets. A Bayesian statistical framework was used to combine previous information about the model parameters with the data likelihood, to yield posterior parameter distributions. The use of the hierarchical statistical model yielded estimates of both variability between experimental groups and uncertainty in TCE toxicokinetics. After adjustment of the model by Markov chain Monte Carlo sampling, estimates of variability for the animal or human metabolic parameters ranged from a factor of 1.5-2 (geometric standard deviation [GSD]). Uncertainty was of the same order as variability for animals and higher than variability for humans. The model was used to make posterior predictions for several measures of cancer risk. These predictions were affected by both uncertainties and variability and exhibited GSDs ranging from 2 to 6 in mice and rats and from 2 to 10 for humans.
AUTHORS' REPLY
Authors: J Crane, C Burgess, R Beasley
Journal: Thorax (1989)

Long acting sulphonamide type drugs may be associated with alveolitis more commonly than is currently realised.Minor degrees of dyspnoea may not be picked up by doctors unaware of the association.Routine three monthly spirometry and possibly chest radiography may be indicated for people taking these drugs.Two particular aspects of our patient's history are the previous dapsone reaction, suggest- ing generalised hypersensitivity to sulphur drugs, and the onset of lung disease despite her taking corticosteroids.
Translumbar Aortography: Present Indications and Technics.
Authors: Arthur C. Beall
Journal: Annals of Internal Medicine (1964)

s1 February 1964Translumbar Aortography: Present Indications and Technics.Arthur C. Beall Jr., M.D., George C. Morris Jr., M.D., Walter S. Henly, M.D., E. Stanley Crawford, M.D., Denton A Cooley, M.D., Michael E. DeBakey, M.D.Arthur C. Beall Jr., M.D.Search for more papers by this author, George C. Morris Jr., M.D.Search for more papers by this author, Walter S. Henly, M.D.Search for more papers by this author, E. Stanley Crawford, M.D.Search for more papers by this author, Denton A Cooley, M.D.Search for more papers by this author, Michael E. DeBakey, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-2-319_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptClinical experience with more than 3,000 translumbar aortograms in the Baylor University College of Medicine Affiliated Hospitals has allowed more exact delineation of the indications for this procedure and the introduction of numerous safety factors in its performance, including hyperhydration, precise needle placement, a limited dose of contrast material, and a single injection. In spite of these safeguards, the inherent toxicity of contrast materials employed in translumbar aortography remained a potential hazard. In the minds of some physicians, this potential hazard has been considered sufficient to prevent the employment of this most useful procedure in some patients in whom it... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Houston, Texas PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1964Volume 60, Issue 2_Part_1Page: 319-320KeywordsHospital medicineSafetyToxicity Issue Published: 1 February 1964 PDF DownloadLoading ...
Biosynthesis and degradation of hyaluronan by nonparenchymal liver cells during liver regeneration
Authors: D Vrochides
Journal: Hepatology (1996)

Hepatic stellate cells (HSC) and endothelial cells of the liver sinusoids synthesize and degrade hyaluronan, respectively. The roles of these cell types in the biosynthesis and degradation of hyaluronan were studied during regeneration following partial hepatectomy. Pure cultures of HSC and liver endothelial cells (LEC) were obtained from regenerating liver at different stages using a Nycodenz gradient followed by discontinuous Percoll gradient. The HSC that established 3 or 4 days after partial hepatectomy synthesized large amounts of hyaluronan when cultured in the presence of fetal calf serum (FCS) or platelet-derived growth factor B-chain homodimer (PDGF)-BB. These cells, as well as LEC, expressed active PDGF β-receptors. Furthermore, the ability of LEC to degrade hyaluronan was decreased at early stages of liver regeneration. The increased synthesis of hyaluronan by HSC and the failure of LEC to catabolize the polysaccharide resulted in elevated hyaluronan concentrations in the blood.
Immunological Diseases
Authors: Roy E. Ritts
Journal: JAMA (1966)

<i>Immunological Diseases</i>is an extraordinary book from several different aspects. Every one of its strengths is at once a weakness, although fortunately most of the latter are minor. One of the book's most unusual aspects is that, while it fulfills a great need in medicine at this time, and to a limited extent in immunology itself, any success it has will be due to its comprehensive coverage of subjects—perhaps even over-comprehensiveness—and the prestige of many of its contributors. The book is ponderously long (in excess of 900 pages) and boasts the remarkable number of 89 contributors and four section editors, in addition to the editor and associate editor. Curiously, a number of these chapters bear acknowledgments to granting agencies, so the book tends to have the appearance of a symposium, and, in fact, some chapters read like contributions to a symposium albeit without the valuable discussions at the end. Consequently,
Rheumatology
Authors: G S Alarcón, K V Straaton
Journal: JAMA (1995)

In some populations, the presence and the dose of the "rheumatoid" epitope have been associated with severe rheumatoid arthritis. Newer treatments include oral antibiotics, oral type II collagen, and a number of biological products. Identification of a mutation in the type II procollagen genes is evidence that some clinical osteoarthritis is genetically related.
Intracranial aneurysm with panhypopituitarism with associated aneurysms of thoracic and abdominal aortas
Authors: J. Curtis
Journal: JAMA (1968)

Aneurysm of the left carotid artery with resultant panhypopituitarism was seen in a patient with associated aneurysm of thoracic and abdominal aorta. Hypopituitarism is thought to have resulted from he presence of the aneurysm with atrophy of the pituitary gland.
Association of Radioactive Chromium with Various Components of Hemoglobin
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
P11.02 Health-related quality of life in meningioma patients - a systematic review
Authors: A. H. Zamanipoor Najafabadi, M. C. M. Peeters, L. Dirven, M. L. D. Broekman, W. C. Peul, M. J. B. Taphoorn, W. R. van Furth
Journal: Neuro-Oncology (2016)
EPID-21. PREDIAGNOSTIC PRESENTATIONS OF GLIOMA IN PRIMARY CARE: A CASE-CONTROL STUDY
Authors: Marthe Peeters, Linda Dirven, Margot de Waal, Mattijs Numans, Martin Taphoorn
Journal: Neuro-Oncology (2018)

Little is known about symptoms and signs of glioma patients in the year(s) before diagnosis. This study aimed to assess the prevalence of clinical symptoms glioma patients may present with to the general practitioner (GP) in the five years prior to diagnosis, and whether these can be distinguished from patients with (1) other central nervous system (CNS) disorders or (2) any other condition. Glioma patients were matched to controls based on age, sex and diagnosis date, using anonymized GP registries. Prevalences of nine prediagnostic symptoms (seizures, headaches, motor impairments, cognitive/mental impairments, visual disorders, mood disorders/fear, general symptoms, sensory complaints and metabolic/endocrine symptoms) were evaluated in the five years prior to diagnosis, and divided into three time periods: 60-24 months, 24–6 months and ‹6 months. RESULT: Thirty-six glioma patients were matched with 72 control patients. In total, 2491 (range 0–102) visits to the GP were analyzed. There were no significant differences between groups in the number of visits over 5 years (711 versus 989 versus 791 in glioma, CNS and other patients respectively; p=0.381), or in each of the three time periods (data not shown). The prevalence of motor symptoms in the period 60-24 months was significantly higher in the CNS patients as opposed to the other groups (4 versus 0 in both groups; both p=0.039). Moreover, ‹6 months prior to diagnosis CNS patients differed significantly in mood disorders/fear compared to other controls (8 versus 0, p=0.012), but not glioma patients versus CNS patients (5 versus 8, p=0.816) or glioma versus other patients (p=0.221). In this sample, glioma patients could not be distinguished from CNS or ‘other’ control patients with respect to the number of GP visits before diagnosis or prediagnostic symptoms. Nevertheless, when mood disorders occur, all CNS disorders should be considered by the GP, including glioma.