tbuckley/cabot-search huggingface dataset:
AIDS commission making its final report
Authors: C. Marwick
Journal: JAMA (1988)

THE PRESIDENTIAL Commission on the Human Immunodeficiency Virus Epidemic is sending its final report to the White House this week. Earlier, it sent an interim report that dealt with three areas of the epidemic: intravenous drug abuse, patient care, and research and drug development (<i>JAMA</i>1988;259:2195-2199). This week's report deals with the remaining topics of its charge: incidence and prevalence of acquired immunodeficiency syndrome in the United States; prevention and education; discrimination; ethics; testing; confidentiality; safety of the blood supply and in the workplace; social and legal issues; the financing of patient care; and international concerns. A month from now, under terms of the executive order that created it a year ago, the commission will be terminated. It is possible that some members of the commission might disagree sufficiently with the final recommendations and conclusions of the majority to issue a minority report. Asked about this, a commission staff member
EFFECT OF DIETARY PROTEINS AND AMINO ACIDS ON THE SUSCEPTIBILITY OF MICE TO BACTERIAL INFECTIONS
Authors: René J. Dubos, Russell W. Schaedler
Journal: The Journal of Experimental Medicine (1958)

Groups of young albino mice were fed continuously four different types of diets and were compared with regard to (1) rate of weight gain; (2) resistance to experimental bacterial infections. The protein content of the four diets was as follows: (a) pellets: a minimum of 21 per cent "crude" protein (according to the manufacturer); (b) diet 20 C: 20 per cent casein; (c) diet 8 C: 8 per cent casein; (d) diet 8 C + AA: 8 per cent casein supplemented with 12 per cent of a mixture of essential amino acids. All diets provided an adequate supply of minerals and vitamins. They were administered ad lib. Three strains of pathogens virulent for mice were used for the infection tests, namely: Staphylococcus aureus, Mycobacterium fortuitum, and Mycobacterium tuberculosis bovis. The bacteria were injected by the intravenous route. The experimental regimens were begun at different times before infection, and were continued until death of the animal, or until termination of the experiment. It was found that mice on the 8 C diet exhibited much greater susceptibility to infection than did mice on the 20 C diet; mice receiving pellets were intermediate between these two groups. The infection-enhancing effect of the 8 C diet could be entirely corrected by amino acid supplementation (diet 8 C + AA). Indeed, mice fed diet 8 C + AA proved the most resistant to infection. The fact that animals fed pellets (which contain a minimum of 21 per cent protein) consistently died faster following infection than did animals fed diets 20 C or 8 C + AA suggests that qualitative characteristics of the protein in the regimen are as important as the quantity of protein fed in determining susceptibility to infection. The differences in susceptibility exhibited by the mice on the four experimental diets were the same whatever the species of bacterial pathogen used for the infection test, the size of the infective dose, and the duration of the disease. There was no apparent relation between the effects of the diets on the weight curves of the animals, and on resistance to infection. Mice on diet 8 C (which were most susceptible) gained weight as rapidly as those on 20 C and more rapidly than those fed 8 C + AA (which were most resistant). All the tests reported in the present paper were carried out with young mice, which were placed on experimental diets within 1 to 2 weeks after weaning. Preliminary experiments suggest that the relation between dietary factors and susceptibility to infection was more difficult to bring out in older animals. There was evidence also that this relation was most apparent during the first weeks that the animals were fed the experimental diets, and became less striking after several weeks.
How ominous is an abnormal scan in bronchogenic carcinoma?
Authors: S. Gravenstein
Journal: JAMA (1979)

Bone, brain, and liver radioisotope scans as prognostic indicators were studied in a series of 162 patients with primary bronchogenic carcinoma. One or more scans positive for metastasis reliably predicted death in less than six months. An abnormal bone scan was most significant (<i>P</i>&lt;.001). Reliability in predicting less than one year's survival in abnormal liver and brain scans was<i>P</i>&lt;.05 for both. Patients with two normal scans were found to have a 50% six-month survival expectation. Brain scans added little information, as they would have predicted a different prognosis for only three of 114 patients who received them. (<i>JAMA</i>241:2523-2524, 1979)
Transactions of the American Association of Obstetricians and Gynecologists.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Seebohm Committee
Authors: M. Barrow
Journal: BMJ (1966)

<h3>Objective</h3> To evaluate the completeness of exercise prescription in randomised controlled trials (RCTs) for patellofemoral pain (PFP), identify which elements are most frequently missing and supplement recommendations based on additional data from authors. <h3>Design</h3> Systematic review. <h3>Data sources</h3> All studies included in the most recent Cochrane review were evaluated. Additionally, the Cochrane search was updated in June 2016 in Cochrane, MEDLINE, EMBASE, PEDro, CINAHL and AMED databases. Two raters independently assessed completeness of reporting using the Toigo and Boutellier mechanobiological exercise descriptors, and Template for Intervention Description and Replication (TIDieR) checklist. Authors were also contacted to provide additional information. <h3>Eligibility criteria for selecting studies</h3> RCTs of exercise interventions for PFP. <h3>Results</h3> We included 38 RCTs. The level of exercise prescription detail was low, with no study providing complete information. The most commonly reported exercise descriptors were the ’duration of the experimental period9 (n=38/38) and ’number of exercise interventions9 (n=35). From TIDieR, the most commonly reported items were the ’intervention name9 (n=38) and ’rationale9 (n=36). The least reported items from the exercise descriptors were ’volitional muscular failure9, ’temporal distribution of contraction modes9, ’time under tension9 and ’recovery between exercise sessions9 (all n=2/38). From TIDieR, the least reported item was ‘How well (fidelity and adherence)’ (n=3/38). 36 authors were contacted, with 22 replies and 13 providing additional exercise prescription details . <h3>Conclusion</h3> Exercise prescriptions in RCTs with proven efficacy for PFP are poorly reported, impairing their implementation in clinical practice. <h3>PROSPERO registration number</h3> CRD42016039138.
ERRATUM
Authors: Olufunmilayo Olopade, Gilberto Schwartsmann, Nagahiro Saijo, Charles Thomas, Daniel Haller, Carlo Garufi, Giuseppe Ettorre
Journal: Journal of Clinical Oncology (2006)

In the Results section of the Abstract, the second to last sentence was given as, "The event-free and overall survival rates were 97% (95% CI, 96.7% to 96.9%) and 97% (95% CI, 96.8% to 97.0%), respectively, at 30 months," whereas it should have read, "The event-free and overall survival rates were 97% (95% CI, 93% to 100%) and 97% (95% CI, 93% to 100%), respectively, at 30 months."However, this does not affect the validity and interpretation of the data.In the Discussion, the second sentence in the fourth paragraph was given as, "in the European Task Force on Lymphoma study, only patients with LRCHL who were previously misclassified as having LRCHL were reviewed," whereas it should have read, "In the European Task Force on Lymphoma study, only patients with LRCHL who were previously misclassified as having LPHL were reviewed."In Table 2, under Risk Factors, the second to last characteristics was given as Ͼ 3 LNAs, whereas it should have been Ն 3 LNAs.
Précis de dermatologie.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SUBSTITUTION BEFORE MEDICAL EXAMINING BOARDS.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
World Bank report says reallocate resources
Authors: C. Marwick
Journal: JAMA (1993)

IN 1990, the nations of the world spent $1.7 trillion, 8% of the total world product, on health services. But in terms of improved health they did not get as much value from this expenditure as they might have. This is the conclusion of the 1993 annual report from the World Bank, Washington, DC. Entitled<i>Investing in Health</i>, the report was prepared by a team headed by Dean T. Jamison, PhD, UCLA School of Public Health, Los Angeles, Calif. The World Bank's annual reports, issued every July, are major statements on international development policy. In the past, they have been devoted to such macroeconomic topics as debt, poverty, and the environment. This year's is the first World Bank annual report ever to be devoted to health. Its 120 000 copies, printed in eight languages, are very widely distributed, sent to the ministers of finance and central banks of every nation
Two Names Added to Additional Contributions Section
Authors: Caroline Meade, Connor Drake, Ralph Snyderman
Journal: JAMA (2016)

Gillian D. Sanders, PhD; Peter J. Neumann, ScD; Anirban Basu, PhD; Dan W. Brock, PhD; David Feeny, PhD; Murray Krahn, MD, MSc; Karen M. Kuntz, ScD; David O. Meltzer, MD, PhD; Douglas K. Owens, MD, MS; Lisa A. Prosser, PhD; Joshua A. Salomon, PhD; Mark J. Sculpher, PhD; Thomas A. Trikalinos, MD; Louise B. Russell, PhD; Joanna E. Siegel, ScD; Theodore G. Ganiats, MD
Reply:
Authors: Tito Livraghi
Journal: Hepatology (2008)

Of course we agree that the appearance of new lesions is a delayed phenomenon after radiofrequency ablation (RFA) or partial resection. We also agree that, being a delayed phenomenon, this factor is of little value in treatment planning and survival prediction. However, even in the presence of adverse prognostic parameters (high alpha-fetoprotein and des-gamma-carboxy prothrombin levels, low grading, and so forth), it is difficult to predict the individual natural history. For instance, our longest survivor presented at the baseline a 3.5-cm infiltrating hepatocellular carcinoma with alpha-fetoprotein level > 400 ng/mL. The patient, initially treated with percutaneous ethanol injection and subsequently with RFA when new lesions appeared, is currently free of desease after 19 years of follow-up. The result of our multivariate analysis simply means that even though the treatment is successful, the prognosis is dependent to the timing of appearance of new lesions. On the basis of your suggestion, we performed a new multivariate analysis with the exclusion of this factor, but the other factors as operability (0.61 instead of 0.63) remained not significant. Tito Livraghi*, * Department of Radiology, Ospedale Civil, Vimercate, Italy.
Galactorrhea and abnormal menses associated with a long-acting progesterone
Authors: R. J. Bolognese
Journal: JAMA (1967)

WE RECENTLY reported the propensity of medroxyprogesterone acetate (Depo-Provera) for causing missed abortion.<sup>1</sup>Subsequent menstrual abnormalities were noted in 15 of 22 such patients, observations also noted by others.<sup>2-4</sup>During our investigation of 58 patients treated with medroxyprogesterone, we uncovered another endocrine abnormality—persistent puerperal galactorrhea. Although other drugs have been associated with this condition, we know of no published report of abnormal lactation associated with medroxyprogresterone. This communication will present five cases in which galactorrhea developed following administration of medroxyprogesterone, as well as the menstrual response in the 36 cases not previously reported. <h3>Methods and Materials</h3> During 1964 and 1965, fifty-seven patients who received medroxyprogesterone for threatened abortion were investigated. The women ranged in age from 21 to 41 years and in parity from 0 to 10. Fifty or 100 mg weekly doses of medroxyprogresterone acetate were initiated during the first trimester in 44 patients and during the
The Risks of Abstinence
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Outcomes in Hospitalized, Organ Transplant Patients with a Penicillin Allergy Label in the United States, 2005-2014
Authors: Jared Nelson, Ismael Carrillo-Martin, Wendelyn Bosch, Lisa Brumble, Justin Oring, Miguel Park, Alexei Gonzalez-Estrada
Journal: Journal of Allergy and Clinical Immunology (2021)
Reply
Authors: Hilary A. Lavery, J.H.M. Pinkerton, M. Callendar
Journal: British Journal of Dermatology (1986)

Journal Article Reply Get access Hilary A. Lavery, Hilary A. Lavery Royal Victoria Hospital, Grosvenor Road, Belfast BT12 6BA, Northern Ireland Search for other works by this author on: Oxford Academic Google Scholar J.H.M. Pinkerton, J.H.M. Pinkerton Royal Victoria Hospital, Grosvenor Road, Belfast BT12 6BA, Northern Ireland Search for other works by this author on: Oxford Academic Google Scholar M. Callendar M. Callendar Royal Victoria Hospital, Grosvenor Road, Belfast BT12 6BA, Northern Ireland Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 114, Issue 4, 1 April 1986, Page 515, https://doi.org/10.1111/j.1365-2133.1986.tb02861.x Published: 01 April 1986
Reference Committees of the House of Delegates
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Phase I Study of the Farnesyltransferase Inhibitor Tipifarnib in a Week-On Week-Off Dose Schedule in Acute Myelogenous Leukemia.
Authors: Mark H. Kirschbaum, Anthony Selwyn Stein, Joseph Tuscano, Jasmine M. Zain, Leslie Popplewell, Margaret R. O’Donnell, Chatchada Karanes, John Wright, Bernadette Pulone, Amalia Rincon, Paul Frankel, Stephen J. Forman, Edward Newman
Journal: Blood (2007)
Neonatal and pediatric cardiovascular crises
Authors: W. Guntheroth
Journal: JAMA (1975)

CRISES of the cardiovascular system in the pediatric age group occur most often in the infant, whose size makes monitoring blood pressure difficult and the dosage of fluids and medications critical. Therefore, some general comments about monitoring and drug dosage may serve well as an introduction to the critical care of infants and children. <h3>Blood Pressure Determination</h3> The blood pressure determination is crucial to the diagnosis as well as to the treatment of circulatory shock. No matter whether auscultation or ultrasonic or other electronic methods are employed,<i>the cuff size is of enormous significance</i>. A cuff that is too small will indicate systolic pressures higher than the true value of the intra-arterial pressure, and a cuff too large will produce readings that may suggest shock in the presence of a normal circulatory state. The width of the air bladder in the cuff should be 20% to 25% wider than the
Cholesterol Agonistics
Authors: John C. LaRosa
Journal: Annals of Internal Medicine (1996)

Considerable evidence links elevated blood cholesterol levels to the development of atherosclerosis. The National Cholesterol Education Program (NCEP) has recently published revised guidelines for detecting and treating hypercholesterolemia in adults. Included in these guidelines is the recommendation that all adults older than 20 years of age know their cholesterol levels. Under the NCEP guidelines, knowledge of cholesterol levels, even if the levels are elevated, does not automatically lead to drug therapy; on the other hand, under these guidelines, adults are not automatically excluded from treatment simply on the basis of age or sex. The guidelines presented by the American College of Physicians in this issue differ from the NCEP guidelines in that they recommend only limited screening, primarily for middle-aged men. This recommendation is based in part on the assumption that overuse of cholesterol-lowering drugs will otherwise become a problem. In fact, a major current problem is underuse of cholesterol-lowering medications, even in patients at high risk for coronary events. The guidelines proposed by the College minimize large elements of the database linking cholesterol to atherogenesis and make unwarranted and unproven assumptions about physician behavior. In its rationale, its potential consequences, and the process by which it was derived, this policy is in error and should be rejected.
"A MODIFICATION OF THE Flagg ANESTHESIA APPARATUS"
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal