tbuckley/cabot-search huggingface dataset:
Sustainable food for a sustainable planet
Authors: None The Lancet Planetary Health
Journal: The Lancet Planetary Health (2017)

In recent years, the impact that food production and consumption have had on the environment has received increasing international attention. Some food production practices and consumption behaviours are putting the environment under a great stress, contributing to climate change. The food sector accounts for around 30% of the world's total energy consumption and accounts for around 22% of total greenhouse gas emissions. With a world population expected to reach about 9 billion by 2050 and with continuing degradation of the planet's resources, how we produce and consume our food is becoming essential in the safeguarding of our planet.
The current status of tumor imaging
Authors: D. L. Lilien
Journal: JAMA (1974)

AMONG the most exciting advances in the treatment of malignant disease has been the dramatic improvement in survival of patients with lymphoma and Hodgkin disease.<sup>1</sup>This has been accomplished by the use of new drug combinations and sophisticated techniques for radiation therapy; drugs and irradiation are often given together or in sequence. Such an approach is being extended to other tumor types, particularly carcinoma of the breast and a variety of tumors originating in the pelvis. The choice of therapy for a given patient depends, to a critical degree, on accurate information on the extent of disease (staging). Many techniques exist for the assessment of the extent of malignant disease. They include clinical examination, laboratory tests, routine roentgenographic procedures, tomography, lymphography, ultrasound, angiography, and even exploratory surgery. The more sophisticated studies, however, may be hazardous, expensive, or not amenable to repetition necessary for assessment of the results of therapy.
INTESTINAL INTOXICATIONS IN INFANCY
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: BMJ (1966)

We publish below a selection of questions and answers of general interest. Siteof B.C.G.Vaccination Q.-What are the clinical disadvantages of giving B.C.G. vaccine into the buttock?A.-B.C.G. vaccine is always given by the intradermal route, and the discomfort and irritation that would be produced by a chronic superficial local lesion in the buttock, together with the probability of local secondary infection, preclude the use of this site.The optimum site for B.C.G. vaccination is in the deltoid region.When a less exposed site is required the vaccine can be given into the skin on the ventro-lateral aspect of the upper one-third of the thigh.This site should never be used in children under 2 years of age because of the risk of regional adenitis and occasionally abscess formation due to constant, mild skin infection caused by irritation from wet napkins.'2
The potent pressor effect of phenylpropanolamine in patients with autonomic impairment
Authors: I. Biaggioni
Journal: JAMA (1987)

We determined the pressor effect of phenylpropanolamine hydrochloride, a widely used sympathomimetic agent, in 14 patients with autonomic failure and orthostatic hypotension. Blood pressure was monitored every five minutes in the sitting position with an automated device. Oral administration of 25 mg of phenylpropanolamine hydrochloride in nine patients produced significant increases in systolic (32 mm Hg), diastolic (15 mm Hg), and mean (21 mm Hg) blood pressures. The pressor effect appeared within the first 60 minutes and was still present at 105 minutes. There was no change in heart rate. Blood pressure was also significantly raised by administration of 12.5 mg of oral phenylpropanolamine hydrochloride in five additional patients. We conclude that administration of 25 mg of phenylpropanolamine hydrochloride elicits a potent pressor response in patients with orthostatic hypotension and that significant hypertension may result. (<i>JAMA</i>1987;258:236-239)
Abstract 4036: The efficacy of immune checkpoint inhibitors in patients with EGFR mutated non small cell lung cancer in retrospective analysis
Authors: Tadaaki Yamada, Soichi Hirai, Akihiro Yoshimura, Satoshi Watanabe, Junji Uchino, Koichi Takayama
Journal: Cancer Research (2019)

Abstract Background The treatment with EGFR-TKIs leads to initial response in most patients with EGFR mutated non-small cell lung cancer (NSCLC). In contrast, little is known the subpopulation of NSCLC patients with EGFR mutations who had clinical outcomes to treat for immune checkpoint inhibitors (ICIs). Therefore, to seek for the eligible cases to treat with ICIs, we retrospectively analyzed the correlation between clinical feature and the efficacy of ICIs in patients with EGFR mutations. Methods/Materials and methods We analyzed a retrospective study of patients with advanced NSCLC harboring with EGFR mutations who were treated with ICIs after the resistance to EGFR-TKIs between February 2016 and April 2018 at six institutions in Japan. The association between clinical outcome and the efficacy or ICIs was investigated. Results We enrolled 27 patients who have EGFR activating mutation. The objective response and disease control rates were higher in patients with uncommon EGFR mutations than in those with common EGFR mutations (71% versus 35.7%, and 57% versus 7%, p= 0.14 and p &amp;lt; 0.01, respectively). Patients with uncommon EGFR mutations or without T790M mutations was associated with a significantly longer median progression-free survival than those with common EGFR mutations or with T790M mutations (p = 0.003, 0.03, respectively). Conclusions Patients with uncommon EGFR mutations and without T790M mutations are associated with best outcomes for the treatment with immunotherapy among EGFR mutated NSCLC in the retrospective analysis. Further research is needed to validate for the clinical biomarkers involved in ICI responders with EGFR mutation. Citation Format: Tadaaki Yamada, Soichi Hirai, Akihiro Yoshimura, Satoshi Watanabe, Junji Uchino, Koichi Takayama. The efficacy of immune checkpoint inhibitors in patients with EGFR mutated non small cell lung cancer in retrospective analysis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4036.
Editorial: aspirin and myocardial infarction: a new national cooperative trial
Journal: JAMA (1975)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
“Characterization of a Topoisomerase II Gene Rearrangement in a Human Small-Cell Lung Cancer Cell Line”
Journal: JNCI Journal of the National Cancer Institute (1993)

“Characterization of a Topoisomerase II Gene Rearrangement in a Human Small-Cell Lung Cancer Cell Line” Get access JNCI: Journal of the National Cancer Institute, Volume 85, Issue 2, 20 January 1993, Page 163, https://doi.org/10.1093/jnci/85.2.163 Published: 20 January 1993
ORGANIZATION SECTION
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
纤维母细胞注射与羊膜纤维母细胞治疗RDEB的对比
Authors: H. Moravvej, F. Abdollahimajd, M.-H. Naseh, Z. Piravar, E. Abolhasani, N. Mozafari, H. Niknejad
Journal: British Journal of Dermatology (2018)

大疱性表皮松解(EB)是一种由至少18种多变基因突变(即某些基因“出错”)引起的水疱型疾病。隐性遗传营养不良型EB (RDEB)是一种独特的EB亚型,由VII型胶原基因(COL7A1)的不同突变引起。本文考察了采用不同的纤维母细胞应用方法来治疗RDEB。本研究在伊朗开展,旨在对比通过注射纤维母细胞(被称为培养的同种异体纤维母细胞)以及在羊膜支架上接种纤维母细胞(FAMS,一类皮肤移植术)来愈合RDEB伤口的效果,或者使用凡士林纱布进行标准伤口护理(SWC)作为对照(作为对照组)。研究招募了七位患者,针对每位患者评估了七处伤口:三处伤口通过注射皮内纤维母细胞治疗,三处通过FAMS治疗,一处进行SWC。在治疗2周和12周后,研究人员评估了伤口大小的变化,并使用被称为QWS的评分系统评估了伤口严重程度。此外,研究人员还通过活检和测试检测了VII型胶原。在两种治疗部位,QWS和伤口大小均降低,而对照组没有任何变化。在治疗2周和12周后,与通过FAMS治疗的伤口相比,通过纤维母细胞注射治疗的伤口大小更小,但对照组未发现明显变化。
Serum cholinesterase is an independent predictor of hepatic encephalopathy, acute-on-chronic liver failure and mortality after transjugular intrahepatic portosystemic shunt insertion in patients with liver cirrhosis
Authors: Lena Thöle, Marie Schultalbers, Nicolas Simon, Jan Hinrichs, Svetlana Gerbel, Markus Cornberg, Michael P. Manns, Bernhard Meyer, Benjamin Maasoumy
Journal: Journal of Hepatology (2020)
BALANCE FAILURE IN SINGLE LIMB STANCE DUE TO ANKLE SPRAIN INJURY: AN ANALYSIS OF CENTRE OF PRESSURE USING THE FRACTAL DIMENSION METHOD
Authors: C Doherty, E Delahunt, C Bleakley, J Hertel, J Ryan, B Caulfield
Journal: British Journal of Sports Medicine (2014)

Background Dynamic stability is ubiquitous to fulfilling daily living activities. Instrumented postural control analysis plays an important role in evaluating the effects of injury on dynamic stability during balance tasks, and is often characterized with measures based on the displacement of the centre of pressure (COP) assessed with a force platform. However, the desired outcome of the task is frequently characterized by a loss of dynamic stability, secondary to injury. Typically, failed trials of balance tasks are discarded during research investigations. Objective To compare the COP characteristics of failed trials in participants with acute lateral ankle sprain (LAS) to successful trial data in another group with the same injury, and a non-injured control group during a single limb stance (SLS) task. Design Cross-sectional. Setting University biomechanics laboratory. Participants 29 participants with acute LAS attempted and succeeded a task of eyes closed SLS on their non-injured limb ( successful injured group ). A separate group of 28 participants with acute LAS attempted and failed the task on their injured limb ( failed injured group ). Finally a non-injured control group of 16 participants successfully completed the task on their non-dominant limb ( successful non-injured group ). Main outcome measure Fractal dimension (FD) of the COP path during the SLS task. Results There was a statistically significant difference at the level of P&lt;.05 in FD scores for the three groups: F (2, 70)=11.61, P&lt;.05 ( successful injured group =1.26±0.15= failed injured group : 1.17±0.14; successful non-injured group =1.38±0.11) with a large effect size. Conclusion Successful eyes-closed SLS is characterized by a larger FD of the COP path trajectory when compared to failed trials, indicating greater utilisation of the available base of support.
Obituary
Authors: Dennis L. Breo
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MEDICINE,
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
IAN DOUGLAS-WILSON SUCCESSOR TO FOX AND WAKLEY
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Premedication, Preparation, and Surveillance
Authors: G D Bell
Journal: Endoscopy (2000)

Once again the staggering variation in IV sedation practice between different countries is highlighted. This year the "to sedate or not sedate" debate focuses on colonoscopy. Several papers on the use of Propofol are reviewed. It remains this authors' opinion that propofol is an anaesthetic agent to be used by (or at least in the presence of) an anaesthetist. Informed consent and the question of what to do if a patient withdraws consent halfway through the procedure are discussed. Predictably further recent papers on the relative merits of midazolam and diazepam are presented plus another report on the use of flumazenil in the recovery period. The use of 3 % hydrogen peroxide solution to aid the visualization of acutely bleeding gastro-duodenal lesions is presented in two papers along with a discussion of its possible mode of action. The use of antispasmodics to aid colonoscopy is further discussed: this year concentrating on the use of hyoscyamine sulphate (as opposed to hyoscine butylbromide, the preferred agent in the UK). The patients receiving hyoscyamine sulphate had significantly shorter caecal intubation times, better sedation and easier colonic insertion. The "downside" was drug-induced tachycardia and the authors caution against the widespread use of this drug until this situation is further clarified. The subject of hypoxaemia at the time of gastroscopy, colonoscopy and ERCP was reviewed last year and further papers are presented in which the incidence of various levels of hypoxia are given. In anaesthetic circles it would be considered totally unacceptable to allow a patient's oxygen saturation to fall below 85 %, and yet we continue to have papers reporting its incidence. This level of desaturation is potential dangerous and the routine use of supplemental oxygen would greatly reduce this unneccessary risk to patients.
Some Dendritic Cells Active Inside Tumors
Journal: Cancer Discovery (2014)

Macrophages within tumors quell immune attacks on the cancer cells, but a new study shows that tumors also contain a small number of CD103+ dendritic cells that activate antitumor CD8+ T cells. The dendritic cells help shrink tumors in mouse models, and their presence might serve as a prognostic biomarker-and improve the odds of survival for patients.
A Galilean Telescope Using an Anterior Chamber Implant as Eye-Piece. A Low Visual Acuity Aid for Macular Lesions
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CEREBRAL METABOLISM AND MENTAL RETARDATION
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal