tbuckley/cabot-search huggingface dataset:
Scheherazade
Authors: Alexandra Pârvan
Journal: Annals of Internal Medicine (2019)

Ad Libitum5 February 2019ScheherazadeAlexandra Pârvan, PhDAlexandra Pârvan, PhDUniversity of Piteâti, Pitesti, Romania (A.P.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M18-2007 Audio Reading - “Scheherazade” Audio. Virginia L. Hood, MD, reads "Scheherazade," by A. Pârvan. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail I came to you full of futureand now I carry death inside melike a fruit: my gift for youlocked safely within.Let's cut the flesh aroundthe trembling place called souland do some research, doctor:my present for your future,and all our time just veiled happening,secret ripening of a fruitimpossible to enjoy, alwaysforbidden.trees ... Author, Article, and Disclosure InformationAffiliations: University of Piteâti, Pitesti, Romania (A.P.)Current Author Address: Alexandra Pârvan, PhD; e-mail, [email protected]it. PreviousarticleNextarticle Advertisement Audio Reading - “Scheherazade” Audio. Virginia L. Hood, MD, reads "Scheherazade," by A. Pârvan. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 5 February 2019Volume 170, Issue 3Page: 209KeywordsForecastingSmell ePublished: 5 February 2019 Issue Published: 5 February 2019 Copyright & PermissionsCopyright © 2019 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Herniated disks and related disorders of the lumbar spine. Surgical treatment in the geriatric patient
Authors: J. A. Epstein
Journal: JAMA (1967)

Twenty-six patients, 65 years of age and older, were studied for symptoms of nerve root compression caused by herniated disks, spondyloarthrosis, and developmental narrowing of the lumbar spinal canal. Both primary and metastatic neoplasms present the essential problems in differential diagnosis. Myelography is mandatory. These patients tolerate decompressive laminectomy and foramenotomy with removal of disks and osteophytes with no unusual risk or morbidity. Eighty percent achieve adequate and lasting relief. Protracted periods of conservative care exhausting the patients' resources are not justified.
Deus ex machina in perspective
Authors: D. K. Harris
Journal: JAMA (1976)

In his August 16, 1976,<i>JAMA</i>editorial entitled, "Are Medical Schools Neglecting Clinical Skills?" George L. Engel, MD, suggests that the clinical acumen of recent medical school graduates suffers substantially due to reliance upon technological support mechanisms.<sup>1</sup>The debate concerning clinical and economic efficacy of technologic innovation has become intense in recent times, particularly as legislation holds the promise of transferring control over medical technology from the medical environment to governmental bureaucracy. To the debate, Dr Engel adds the concern that technology has eroded the clinician's ability to render sound, intellectual judgment. Reliance upon a computer or other mechanical contrivances to develop clinical data may portend the diminution of clinical skills, and there may be the potential for educational deficits concerning the<i>conceptual</i>determinants upon which mechanized clinical data development is predicated. However, to impute causality for these prospects to an overabundance of technology represents a non sequitur that
Possible Role of 5-Hydroxytryptamine in Toxemia of Pregnancy
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
JOSEPH PANCOAST (1805-1882) SURGEON AND ANATOMIST
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Imported Wild Poliovirus Causing Poliomyelitis—Bulgaria, 2001
Journal: JAMA (2001)

In March 2001, a 13-month-old unvaccinated Roma (i.e., gypsy) girl from Bourgas, Bulgaria, had onset of bilateral leg weakness. The National Enterovirus Laboratory in the capital city of Sofia subsequently isolated a wild type 1 poliovirus in the patient's stool. In April, a second case, with wild type 1 poliovirus isolate was found in lambol located approximately 50 mileswest of Bourgas in an unvaccinated 26-month-old Roma girl who had onset of paralysis of both legs. Subsequent analyses indicated that these viruses were related closely to a strain isolated from Uttar Pradesh, India, in July 2000. A third confirmed case with clinical and serologic evidence of poliomyelitis was diagnosed in a 3-month-old Roma boy in Bourgas who had onset of paralysis on May 7. Following the identification of the poliovirus, the Bulgarian Ministry of Health implemented contact investigations, screening of children at high risk, retrospective record review, intensified acute flaccid paralysis (AFP) surveillance, and mass vaccinations. This report summarizes the outbreak investigation and supplemental vaccination activities in response to these polio cases. High routine vaccination coverage and certification standard AFP surveillance are necessary to detect rapidly and prevent the spread of poliovirus importations in areas and countries where polio is not endemic.
THE RELATION OF GALLSTONES TO PEPTIC ULCER
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cigarette smoking in China. Prevalence, characteristics, and attitudes in Minhang District
Authors: Y. L. Gong
Journal: JAMA (1995)

<h3>Objective.</h3> —To determine the prevalence, pattern, and financial implications of cigarette smoking and the attitudes toward and knowledge of the health effects of tobacco use in a population in China. <h3>Design.</h3> —A two-stage, stratified cluster survey using door-to-door interviews. <h3>Setting.</h3> —Minhang District, China (near Shanghai), with a population of 506 000. <h3>Participants.</h3> —A total of 3423 males and 3593 females aged 15 years and older. <h3>Main Outcome Measures.</h3> —Smoking prevalence, age of initiation of smoking, reasons for smoking, knowledge of tobacco hazards, and costs of smoking. <h3>Results.</h3> —A total of 2279 males (67%) but only 72 females (2%) smoke. Many males initiate smoking in adulthood. A total of 1156 males (50.7%) began smoking between 20 and 24 years of age, and 666 (29.2%) began between 25 and 39 years of age. Among all respondents, 6202 (88.4%) believe smoking is harmful for both the smoker and those exposed passively to the smoke. Only 332 (14.1%) of all male smokers reported a desire to quit smoking. Current smokers spent an average of 3.65 yuan daily on cigarettes or 1332 yuan yearly (8.5 yuan per US dollar), which represents 60% of personal income and 17% of household income. <h3>Conclusions.</h3> —The survey reveals a dangerous health situation that in all likelihood will worsen. More than two thirds of men smoke, and people in successive age cohorts start smoking at earlier ages. Smokers spend a substantial proportion of their income on cigarettes. There is a low rate of quitting and a low desire to quit despite high awareness of the health hazards. Tobacco control measures need to be implemented urgently in China. (<i>JAMA</i>. 1995;274:1232-1234)
Abstract 374: Targeted Deletion of A <sub>2B</sub> Adenosine Receptors Attenuates the Protective Effects of Myocardial Postconditioning
Authors: Xinglin Tan, Stephen L Tilley, Thomas Krahn, Bunyen Teng, S. J Mustafa, Polly A Hofmann, R. R Morrison
Journal: Circulation (2008)

Endogenous adenosine is an important ligand trigger for the cardioprotective effects of postconditioning (PostCon). To assess the hypothesis that A 2B adenosine receptor (A 2B AR) activation contributes to PostCon-induced protection, global ischemia-reperfusion was performed with and without PostCon or the selective A 2B agonist, BAY 60 – 6583 (BAY), in isolated wild-type (WT) and A 2B AR knockout (A 2B KO) mouse hearts. In WT hearts, PostCon improved post-ischemic recovery of left ventricular developed pressure (LVDP) to 63.3±1.6 % of pre-ischemic baseline vs. 49.9±1.6 % in non-PostCon controls (CTL), lowered end diastolic pressure (EDP) to 15.8±1.5 mmHg vs. 27.9±1.6 mmHg in CTL, and reduced coronary efflux of cardiac troponin I (cTnI) to 2507±359 ng/g heart weight vs. 4693±343 ng/g in CTL (n=12 both groups, p &lt;0.05 each comparison). Treatment with BAY in the first two min of reperfusion mimicked beneficial effects of PostCon in WT hearts (LVDP: 64.7±2.0 % baseline, EDP: 16.2±2.0 mmHg, cTnI: 3311±366; n=13, not significant compared to respective PostCon values). Real-time PCR confirmed absence of A 2B AR in A 2B KO hearts and demonstrated no changes in expression of other adenosine receptor subtypes compared with WT hearts. In A 2B KO hearts, neither PostCon nor BAY improved recovery of LVDP (50.8±1.6 % baseline for CTL vs. 54.5±1.7 % with PostCon vs. 53.0±1.4 with BAY; n=6 each group), and neither affected EDP or release of cTnI. During reperfusion, both PostCon and BAY increased survival kinase signaling through Akt and ERK1/2 phosphorylation in WT but not A 2B KO hearts. In non-ischemic WT hearts, Akt and ERK1/2 phosphorylation was increased by both BAY treatment and application of the PostCon stimulus. These data demonstrate that the protective effects of PostCon are attenuated by targeted deletion of A 2B AR and are mimicked by selective A 2B AR activation, suggesting A 2B AR activation is an important trigger leading to PostCon-induced myocardial protection.
Re: Evanguelos Xylinas, Michael Rink, Eugene K. Cha, et al. Impact of Distal Ureter Management on Oncologic Outcomes Following Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2012.04.052
Authors: Hao Lun Luo, Po Hui Chiang
Journal: European Urology (2012)
The Pathology of the Eye.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hospital competition and surgical length of stay
Authors: J. C. Robinson
Journal: JAMA (1988)

The hypothesis that competitive pressures encourage hospitals to accommodate patient and physician preferences for longer lengths of stay was tested. Seven hundred forty-seven nonfederal short-term hospitals were divided in terms of the number of neighboring hospitals within a 24-km radius, and this measure of hospital concentration and competition was measured against length of stay for ten surgical procedures, using 1982 data on 498454 patient discharges. Patient, physician, and hospital characteristics associated with length of stay were controlled for. Competition-related percentage increases in length of stay were identified for all procedures, including total hip replacement (14.8%), transurethral prostatectomy (13.9%), intestinal operations (14.0%), stomach operations (14.7%), hysterectomy (6.9%), cholecystectomy (9.1%), hernia repair (10.5%), appendectomy (8.4%), cardiac catheterization (22.9%), and coronary artery bypass graft surgery (21.2%). It was concluded that there is a strong association between the number of hospital competitors in the local market and the average length of stay in US hospitals. (<i>JAMA</i>1988;259:696-700)
EPICONDYLITIS HUMERI
Authors: Lever F. Stewart
Journal: JAMA (1930)

<h3>To the Editor:</h3> —In connection with the article entitled "Epicondylitis Humeri," by Drs. K. G. Hansson and I. D. Horwich (The Journal, May 17), I would call attention to two references: Stewart, L. F., and Ross, G. A.: A Study of Sprain-Fractures, Ann. Surg. 55: 71-87, 1912. Stewart, L. F., and Ross, G. A.: A Study of Sprain-Fracture as an Essential to the Occurrence of Dislocation, Ann. Surg. 56:599-621, 1912. These two papers present considerable evidence showing the superiority in tensile strength of muscle and tendon, as well as ligament, over bone. In the light of the evidence recorded in these papers, certain of the cases of "epicondylitis humeri, or tennis elbow," should properly be recorded as sprain-fractures. Priority in scientific or experimental observations seems to me quite unimportant; but the present-day tendency of giving an unusual name to comparatively simple conditions is harmful to the patient and reflects on
Erratum: A genome-wide association study identifies susceptibility loci for Wilms tumor
Authors: Clare Turnbull, Elizabeth R Perdeaux, David Pernet, Arlene Naranjo, Anthony Renwick, Sheila Seal, Rosa Maria Munoz-Xicola, Sandra Hanks, Ingrid Slade, Anna Zachariou, Margaret Warren-Perry, Elise Ruark, Mary Gerrard, Juliet Hale, Martin Hewitt, Janice Kohler, Sheila Lane, Gill Levitt, Mabrook Madi, Bruce Morland, Veronica Neefjes, James Nicholson, Susan Picton, Barry Pizer, Milind Ronghe, Michael Stevens, Heidi Traunecker, Charles A Stiller, Kathy Pritchard-Jones, Jeffrey Dome, Paul Grundy, Nazneen Rahman
Journal: Nature Genetics (2013)
Abstract 3715: Cancer as a consequence of breaking through evolutionary constraints on longevity
Authors: Jaime F. Modiano, Aaron L. Sarver
Journal: Cancer Research (2019)

Abstract It is well known that the risk of cancer increases with age, but when viewed through a comparative lens, this risk is species specific and exists at a relatively low background in the animal kingdom. The exceptions, where cancer is a major cause of mortality, are humans and companion dogs and cats. Indeed, it is estimated that more than 50% of pet dogs that reach the age of 10-years will die from cancer. Colloquially, there is a perception that there is a “cancer epidemic” in dogs caused by exposures to real or perceived mutagens, but this hypothesis is based on presumptions for which supporting evidence is weak or absent. Here, we propose an alternative hypothesis, that replacing natural selection with artificial selection for form and function, and superimposing longevity that breaks the evolutionary constraints for that species inevitably creates cancer-prone phenotypes. Modern pet dogs have achieved a social status equivalent to human family members. With this have come better health care, reduced early mortality, and greater longevity. Although dogs were first domesticated15,000 to 20,000 years ago and breeds were derived over the last 200 to 400 years, significant gains in longevity and the recognition of cancer as a major cause of mortality in pet dogs have taken place over the past 40 to 60 years, coinciding with the transition of dogs from working animals to pets. Breaking through the evolutionary constraint on longevity comes at a price: long-lived species such as elephants, whales, mole rats, and others have acquired a diversity of cancer-protective mechanisms, achieving a balance between longevity and their reproductive and energetic investments over tens of millions of years. But no such cancer-protective mechanisms have been identified in dogs, or for that matter in humans. In both species, risk increases with age, but in dogs, risk is magnified by artificial selection. Osteosarcoma provides an example that can be generalized. The underlying causal factor is selective breeding for large size, but this is only able to manifest itself because modern pet dogs exceed their evolutionarily expected lifespan by at least 2 or 3 times. We conclude that appreciating the role of longevity as a major cause of cancer in pet dogs, as well as in other model organisms will improve our ability to design and interpret experiments that will show greater fidelity when translated to humans, where the same risk factors are operative, although they are partly masked by the influence of behavioral or occupational exposures to strong mutagens. Citation Format: Jaime F. Modiano, Aaron L. Sarver. Cancer as a consequence of breaking through evolutionary constraints on longevity [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 3715.
Expression of Concern: Inhaled Ethyl Nitrite Prevents Hyperoxia-impaired Postnatal Alveolar Development in Newborn Rats
Authors: Paul Blanc, Carrie Redlich
Journal: American Journal of Respiratory and Critical Care Medicine (2019)

Respiratory Society Statement."Indeed, those were implicit goals that led our international taskforce members to undertake this in-depth review (1).From the onset, we recognized that in focusing on selected nonmalignant respiratory conditions, there would be other occupational associations that we would not be able to address in depth.For example, Table E2 in the online supplement of Reference 1 describes a number of other pulmonary disorders associated with occupational exposures (with supporting citations in the main publication).These include acute eosinophilic pneumonia, bronchiolitis (obliterative, proliferative, and lymphocytic), cryptogenic organizing pneumonia, desquamative interstitial pneumonia, diffuse pulmonary hemorrhage, lipoid pneumonia, nonspecific interstitial pneumonia, and respiratory bronchiolitis interstitial lung disease (1).Many of these disorders fall into the interstitial lung disease group emphasized in the letter by Dr. Lee and Dr. Strek.The authors also raise the important point that autoimmune conditions such as rheumatoid arthritis may not be appreciated as occupationally triggered by silica and other workplace exposures.In that context, it is important to note that concomitant lung disease may not be overt in such syndromes (2).It is our hope that further research and in-depth reviews will continue to shed light on underappreciated occupational contributors to disease and prioritize a reduction in the burden of these preventable conditions.
Glaucoma Tests: Population Study
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"Xanthine oxidase inhibition reduces reactive nitrogen species production in COPD airways”. M. Ichinose, H. Sugiura, S. Yamagata, A. Koarai, M. Tomaki, H. Ogawa, Y. Komaki, P.J. Barnes, K. Shirato, T. Hattori.Eur Respir J2003; 22: 457–461.: Table 1
Journal: European Respiratory Journal (2004)