tbuckley/cabot-search huggingface dataset:
Guide for collaboration of physician, social worker, and lawyer in helping the unmarried mother and her child
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Art: Exodus
Authors: S. Hargreaves
Journal: BMJ (2003)

Rating: ![Graphic][1]</img>![Graphic][2]</img>![Graphic][3]</img>![Graphic][4]</img> Amid the xenophobic and hostile debate that hangs like a dark cloud over the treatment of refugees and asylum seekers arriving at British shores comes this timely exhibition. It is a welcome exposé of the intense human suffering such people face in other corners of the world on fleeing their homes, often within the very conflict zones that fuel the global migration phenomenon. And as photographer Sebastia ~o Salgado so aptly notes, “It is a disturbing story.” A Brazilian, who fled to Europe to escape military rule in 1969, Salgado has spent the past few years documenting the lives of populations on the move throughout Asia, Africa, central Europe, … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif [3]: /embed/inline-graphic-3.gif [4]: /embed/inline-graphic-4.gif
Clotting Patterns in Aqueous Humor
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Shelf Life Of Whole Blood Is Doubled
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Catecholamines
Authors: Julius Axelrod, Richard Weinshilboum
Journal: New England Journal of Medicine (1972)

THE catecholamines — dopamine, adrenaline (epinephrine) and noradrenaline (norepinephrine) — are found at specific locations in tissues. Noradrenaline is present mainly in the sympathetic nerves of the peripheral and central nervous systems and acts locally on effector cells of vascular smooth muscle, adipose tissue, liver, heart and brain as a neurotransmitter. Adrenaline is primarily located in the adrenal medulla and acts mainly as a hormone on distant target organs after its release from the adrenal gland into the bloodstream. Dopamine has two functions: it serves as a precursor of noradrenaline, and it presumably functions as a neurotransmitter in the areas . . .
Chemerin, A Novel Adipokine in the Regulation of Angiogenesis
Authors: Kiymet Bozaoglu, Joanne E. Curran, Claire J. Stocker, Mohamed S. Zaibi, David Segal, Nicky Konstantopoulos, Shona Morrison, Melanie Carless, Thomas D. Dyer, Shelley A. Cole, Harald H. H. Goring, Eric K. Moses, Ken Walder, Michael A. Cawthorne, John Blangero, Jeremy B. M. Jowett
Journal: Endocrine Reviews (2010)

ABSTRACT Context Chemerin is a new adipokine associated with obesity and the metabolic syndrome. Gene expression levels of chemerin were elevated in the adipose depots of obese compared with lean animals and was markedly elevated during differentiation of fibroblasts into mature adipocytes. Objective To identify factors that affect the regulation and potential function of chemerin using a genetics approach. Design, setting, patients and intervention Plasma chemerin levels were measured in subjects from the San Antonio Family Heart Study (SAFHS), a large family-based genetic epidemiological study including 1354 Mexican American individuals. Individuals were randomly sampled without regard to phenotype or disease status. Main Outcome Measures A genome wide association analysis using 542,944 SNPs in a subset of 523 of the same subjects was undertaken. The effect of chemerin on angiogenesis was measured using human endothelial cells and interstitial cells in co-culture in a specially formulated medium. Results Serum chemerin levels were found to be highly heritable (h2 = 0.25; P = 1.4 x 10−9). The SNP showing strongest evidence of association (rs347344; P = 1.4 x 10−6) was located within the gene encoding EDIL3, which has a known role in angiogenesis. Functional angiogenesis assays in human endothelial cells confirmed that chemerin significantly mediated the formation of blood vessels to a similar extent as VEGF. Conclusion Here we demonstrate for the first time that plasma chemerin levels are significantly heritable and identified a novel role for chemerin as a stimulator of angiogenesis.
Evaluation of beat-to-beat change in left ventricular diastolic function during atrial fibrillation by color M-mode (CMM) flow propagation velocity Peggy K. Han, Tomotsugu Tabata, Junko Watanabe, Benjamin Cheong, Neil L. Greenberg, Allan L. Klein, James D. Thomas, Richard A. Grimm. The Cleveland Clinic Foundation, Cleveland, OH
Journal: Journal of the American College of Cardiology (2001)
Sex experts and medical scientists join forces against a common foe: AIDS
Authors: M. F. Goldsmith
Journal: JAMA (1988)

NEW STRATEGIES for controlling acquired immunodeficiency syndrome (AIDS) were sought at the first national conference to focus the efforts of sexual behavior experts as well as medical scientists on the pandemic disease. A four-day symposium, "AIDS and Sex: An Integrated Biomedical and Biobehavioral Approach," held in Bloomington, Ind, was cosponsored by the Kinsey Institute for Research in Sex, Gender, and Reproduction, the National Institute of Allergy and Infectious Diseases, and the National Institute of Child Health and Human Development. Nearly 100 researchers and clinicians, including several from other countries, reported results of studies, described ongoing programs, and suggested future action. In an atmosphere heavy with a sense of mission but balanced by the ebullient oversight of cochair June M. Reinisch, PhD, professor of psychology at Indiana University and director of the Kinsey Institute, the participants shared perspectives and joined in spirited discussions aimed at reaching solutions to a problem that,
THE RELATION OF TRAUMA TO PARALYSIS AGITANS
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Primary prevention of ovarian cancer
Authors: D. A. Grimes
Journal: JAMA (1993)

Ovarian cancer remains the deadliest gynecologic malignancy in the United States, killing more women each year than cervical and endometrial cancers combined. Despite aggressive operations and intensive chemotherapy, the 5-year survival rate is less than 40%.<sup>1</sup>Complications such as bowel obstruction, inanition, ascites, and pleural effusions can make this a wretched way to die. Hence, the finding of Hankinson et al<sup>2</sup>in this issue of<i>JAMA</i>is heartening: tubal sterilization may protect against this malignancy. See also p 2813. The Nurses' Health Study is not the first to observe this protection.<sup>3-5</sup>The importance of this research, however, stems from its design: a large, prospective cohort study. Cohort studies avoid some of the vexing problems of case-control studies, such as selection of an appropriate control group. Ascertainment bias is unlikely to have accounted for these results. The respondents were knowledgeable health professionals, and medical records confirmed reported illness. While
Hepatology Highlights
Authors: Kamolyut Lapumnuaypol, Christopher J. Danford, Daryl T.Y. Lau, Joseph F. Pisa, Robert S. Brown, Angel Morales Santiago, Giorgio Roccaro, Amaia Navarro‐Corcuera, Robert E. Schwartz, Enis Kostallari, Nicholas W. Russo, Petra Hirsova, Jessica L. Maiers, Nidhi Jalan‐Sakrikar
Journal: Hepatology (2020)
Comparison of surgical repair with balloon angioplasty for coarctation and recoarctation: A twenty-three-year review Gordon H. Oron, Ronald J. Walhout, Jaco C. Lekkerkerker, Francois Hitchcock, Paul A. Hutter, Erik J. Meijboom. Wilhelmina Children's Hospital/University Medical Center, Utrecht, The Netherlands
Journal: Journal of the American College of Cardiology (2001)
XX/XY lymphoid chimerism in a boy with fatal lymphohistiocytic proliferation
Authors: G. Cividalli
Journal: JAMA (1981)

XX/XY chimerism, present in peripheral blood and bone marrow cells, but absent in other somatic tissues, was demonstrated in a 6-year-old patient. The initial clinical presentation with "butterfly" rash, pancytopenia with a hemolytic component, and hypergammaglobulinemia was suggestive of an immune disorder. Infiltration of skin, bone marrow, and lymph nodes with histiocytes, without disruption of the general configuration, was similar to the findings in familial lymphohistiocytosis. The results of specific cellular markers and of cytogenetic and immunologic studies are analyzed and the nature of the disease and origin of the chimeric state are discussed. The most likely explanations include a chronic graft-vs-host reaction induced by proliferation of foreign lymphoid cells derived from a blood transfusion that the child had received during infancy, or proliferation of neoplastic cells present in the transfused blood. (<i>JAMA</i>1981;246:1917-1920)
Judicial Executions
Authors: J. J. de Zouche Marshall
Journal: BMJ (1888)

kinds had been got together-old and modern portraits of past and present medical worthies of SheffBeld and elsewhere, and other things of local and medical interest.The graphophone (Tainher's) was exhibited, and its marvellous properties excited tlle most lively interest; and it was the centre throughouit the evening of an appreciative throng.Mr. Edmunds, the introduicer into this country of the instrument, kindly attended himself.The visitors, most of whom had assembled earlier, adjourned at 8.30 to the Hlall in Firth College, to hear Sir Aind:rew Clark's ad- dIress.The chair was occupied by Mr. W. F. Favell, in the absence of Dr. de Bartolome, the President of the School.The hiall was well filled, and Sir A. Clark's address was listened to with marked at- tention and evident appreciation.It was generally felt that it was typically the address for a mixed audienice.The lecturers of the school feel greatly indebted to Sir A. Clark, not only for his present address, but for his attendance two or three years before, to advocate the claims of a medical school to the generous assistance of the public.This point he again pressed upon his audience.Other parts of his address, dealing
"BASAL METABOLISM"—A DISCLAIMER OF RESPONSIBILITY
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Some Physicians Protest "High-Stakes" Tests
Authors: M. Mitka
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Diagnostic Value of Marrow Hemosiderin Patterns.
Authors: Robert K. Nixon
Journal: Annals of Internal Medicine (1968)

s1 May 1968The Diagnostic Value of Marrow Hemosiderin Patterns.Robert K. Nixon, M.D., F.A.C.P.Robert K. Nixon, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-68-5-1171_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMarrow hemosiderin patterns in over 500 patients 11 were analyzed to determine their diagnostic value. Marrows were prepared according to a modification of the method of Rath and Finch. Evaluation of quantity and predominant particle size of iron was made. In each type of anemia encountered (iron lack, primary or secondary refractory, hemolytic, hemorrhagic, and APA factor deficiency), consistent correlation of the hemosiderin pattern with known ferrokinetics as established by59Fe data was obtained. Confirmation of the previously reported finding of absence of marrow iron in polycythemia vera was made in all cases studied. Furthermore, a hemosiderin pattern was observed... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Detroit, Michigan PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1968Volume 68, Issue 5Page: 1171-1171KeywordsBone marrowHemolytic anemiaPolycythemia vera Issue Published: 1 May 1968 PDF downloadLoading ...
Therapeutics
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of Deep Femoral Thrombophlebitis on Circulation of Lower Extremities
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Characterization of LASEP3 as a serological and prognostic biomarker and a therapeutic target for lung cancer.
Authors: Atsushi Takano, Yusuke Nakamura, Yataro Daigo
Journal: Journal of Clinical Oncology (2015)

11088 Background: Characterization of cancer-specific oncoproteins could lead to the development of novel diagnostic/prognostic biomarkers or therapeutic targets. Methods: To develop new cancer biomarkers and therapies targeting oncoproteins, we used the strategies as follows: i) Identification of up-regulated genes in non-small cell lung cancers (NSCLCs) by means of cDNA microarray, ii) Validation of clinicopathological significance of their protein expression by tissue microarray, iv) Examination of the growth/invasive effect on cancer cells by siRNA assay, and v) Measurement of their serum protein levels by ELISA. Results: We identified a secreted protein, LASEP3 (lung cancer-associated serum protein 3) as a candidate. Immunohistochemical staining of LASEP3 showed that strong LASEP3 positivity was observed in 198 (54.8%) of 361 earlier stage NSCLCs that had undergone curative surgery. High level of LASEP3 expression was associated with poor prognosis for NSCLC patients. (P = 0.0183 by log-rank test). Serum LASEP3 levels were higher in NSCLC patients than in healthy volunteers. The proportion of serum LASEP3-positive cases was 160 (61.8%) of 259 NSCLCs (49.4% for stage I-II, 67.4% for stage III-IV), while 6 (5.5%) of 109 healthy volunteers were falsely diagnosed. Moreover serum LASEP3 levels were significantly higher in breast and colon cancer patients than in healthy volunteers. Furthermore, reduction of LASEP3 by siRNAs suppressed lung cancer cell proliferation and invasion. Flow cytometric analysis of these tumor cells transfected with siRNAs for LASEP3 revealed a significant increase of the cells at the sub G1 phase and induced the apoptosis of the cancer cells. Furthermore, subsequent microarray analysis of these cancer cells transfected with siRNAs identified several candidate downstream genes of LASEP3 that relate to cell growth/invasion signals. Conclusions: LASEP3 is a possible diagnostic and prognostic biomarker and a therapeutic target for lung and various types of solid cancer.
Efficacy of Nilotinib (formerly AMN107) in Patients (Pts) with Newly Diagnosed, Previously Untreated Philadelphia Chromosome (Ph)-Positive Chronic Myelogenous Leukemia in Early Chronic Phase (CML-CP)
Authors: Jorge Cortes, Susan O’Brien, Dan Jones, Alessandra Ferrajoli, Marina Konopleva, Gautam Borthakur, Guillermo Garcia-Manero, Laurie A. Letvak, Hagop Kantarjian
Journal: Blood (2008)