tbuckley/cabot-search huggingface dataset:
Modern Dentistry.
Journal: JAMA (1918)

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Incorrect Information in Text and Table
Authors: Daniel Cohen, Wilfred Lumbang, Alan Boyd, Jeffrey Sosman, Jeffrey Zwerner, Sosman Cohen, Sosman Boyd
Journal: JAMA Dermatology (2014)

Mackenzie R. Wehner, MPhil; Mary-Margaret Chren, MD; Danielle Nameth, BA; Aditi Choudhry, MD; Matthew Gaskins, MPH; Kevin T. Nead, MPhil; W. John Boscardin, PhD; Eleni Linos, MD, DrPH
Abstract 444: Continuous, high throughput microfluidic device to monitor circulating tumor cells in cancer patients
Authors: Kaylee Smith, Tae Hyun Kim, Costanza Paoletti, Douglas H. Thamm, Daniel F. Hayes, Sunitha Nagrath
Journal: Cancer Research (2019)

Abstract Analysis of circulating tumor biomarkers, designated “liquid biopsies” are less invasive and lower risk to the patient and might replace or complement standard tissue biopsies to determine prognosis, predict benefit from specific therapies, or monitor patients with cancer. Circulating tumor cells (CTCs) are extremely rare, with only 1-10 CTCs per mL of blood. Current technologies typically process 1-10 mL of blood ex vivo. We report an in vivo, indwelling CTC-capture device that is analogous to a Holter monitor used to interrogate cardiac rhythm abnormalities over long periods of time. The system incorporates a dual lumen intravenous catheter that directs blood from the vein into a small (~ the size of a wristwatch) capture carriage by virtue of a peristaltic pump. The carriage contains a CTC capture chip which separates CTCs from whole blood based on flow differences and solid phase anti-EpCAM capture, while the remaining whole blood is returned to the venous system via the dual lumen catheter. The chip is then removed from the carriage for further enumeration and characterization of the CTCs. In a proof of principle set of experiments, the system was placed into investigational canines into which fluorescently labeled human breast cancer cells were injected intravenously. Although the vast majority of these xeno-cancer cells were rapidly removed from circulation, the system captured “CTCs” over a 2 hour time period more successfully than was seen in simultaneous blood draws for ex vivo enumeration over the same time. No adverse effects were observed in the subjects at the time of the experiments or over the succeeding 48 hours after removal of the IV system.Our system permits interrogation of a much larger volume of blood than can be processed with standard blood draws. The larger processed volume will drastically increase the number of cells isolated which in turn increases the number of downstream assays that can be performed. This study is focused on developing a high throughput microfluidic device that can detect CTCs and implementing it in a canine model. Citation Format: Kaylee Smith, Tae Hyun Kim, Costanza Paoletti, Douglas H. Thamm, Daniel F. Hayes, Sunitha Nagrath. Continuous, high throughput microfluidic device to monitor circulating tumor cells in cancer patients [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 444.
THE TRANSPLANTATION OF GLANDULAR STRUCTURES
Journal: JAMA (1920)

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PLEURAL AND PERITONEAL PAINS
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Multicenter Survey of Diabetic Pregnancy in France
Journal: Diabetes Care (1991)

Objective To describe the medical care and outcome of diabetic pregnancy and gestational diabetes in France and study their associations with glycemic control. Research Design and Methods We performed a multicenter prospective survey with systematic collection of clinical and biological data (HbA1c analysis in a central laboratory) at five successive examinations and consecutive recruitment of women at any stage of pregnancy in 46 specialized centers from all parts of France. Pregnancies were followed to the end. There were 483 single pregnancies (232 women with insulin-dependent diabetes mellitus [IDDM], 78 with non-insulin-dependent diabetes mellitus [NIDDM], and 173 with gestational diabetes mellitus [GDM]), and 11 twin births (8 IDDM, 3 GDM). Results We observed 30 abortions (6%), 8 perinatal deaths (1.8%, 4 IDDM, 4 GDM), and 13 congenital malformations (3%). In the 11 twin pregnancies, there were 7 congenital malformations. Premature births and cesarean sections were found very frequently (42 and 61% IDDM, 29 and 55% NIDDM, 22 and 32% GDM, respectively). In the three groups, birth weight adjusted for gestational age was much &amp;gt; national reference values. HbA1c levels during the first trimester were significantly higher in women who aborted (mean ± SE 7.1 ± 0.4 vs. 5.6 ± 0.1%, P &amp;lt; 0.001) and those who gave birth to malformed infants (6.8 ± 0.4 vs. 5.9 ± 0.1%, P &amp;lt; 0.05). Conclusions Perinatal mortality was slightly higher in diabetic women than the general population (1.8 vs. 1.2%), but the prematurity rate was much higher, possibly due to an interventionist policy in some centers. Fetal loss and congenital malformations were associated with poor glycemic control.
From the National Institutes of Health. Saliva inhibits HIV infectivity
Authors: J. B. Wyngaarden
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
New Anticoagulants
Authors: John W. Eikelboom, Jeffrey I. Weitz
Journal: Circulation (2010)

T hromboembolism involving the arterial or venous circu- lation or arising from the heart is a common cause of morbidity and mortality.Rapidly acting parenteral anticoagulants, such as heparin, are used for the prevention and initial treatment of thromboembolism and during revascularization procedures, 1 whereas the slower-acting vitamin K antagonists (VKAs) are used for long-term therapy. 2 The introduction of low-molecular-weight heparin (LMWH) and fondaparinux has simplified parenteral anticoagulant therapy, and these agents have replaced heparin for many indications. 3Development of new oral anticoagulants to replace VKAs has been slower than that of parenteral agents.Ximelagatran, an oral thrombin inhibitor, was briefly licensed in Europe but was withdrawn in 2006 because of potential hepatic toxicity. 4lthough this set the field back for several years, the situation has changed with the recent introduction of dabigatran etexilate, a new oral thrombin inhibitor, and rivaroxaban, an oral factor Xa (fXa) inhibitor. 3Licensed in Europe and Canada for prevention of venous thromboembolism (VTE) in patients undergoing hip or knee arthroplasty, dabigatran etexilate and rivaroxaban streamline out-of-hospital thromboprophylaxis because the drugs can be given once daily in fixed doses without coagulation monitoring.The greater unmet medical need, however, is to find a replacement for VKAs for long-term therapy, particularly stroke prevention in patients with atrial fibrillation (AF).The results of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) trial, which compared dabigatran etexilate with warfarin for stroke prevention in patients with AF, demonstrate that the new oral anticoagulants have the potential to be more effective and safer than VKAs. 5 If these results are replicated with other agents and in additional clinical settings, then oral thrombin and fXa inhibitors will soon replace VKAs.This article (1) outlines the limitations of established parenteral and oral anticoagulants, (2) describes the potential advantages of the new agents, (3) briefly reviews the pharmacology and clinical trial results with new anticoagulants in advanced stages of development, and (4) provides perspective on the opportunities and challenges with the new parenteral and oral anticoagulants.
Oxford revisited
Authors: W. C. Gibson
Journal: JAMA (1980)

WINSTON Churchill's old school song "Forty Years On" says it all. To return to Oxford 40 years after graduation is to "wonder what we were like at our work and our play." But not solely—for Oxford, always changing is largely the same. For the sake of perspective let us proceed from what was and still is, and then look at the very recent and the proposed. Precariously, down a narrow lane, (Fig 1) thronged with bicycles and tourists, I proceeded to the original gate of New College—which despite its name celebrated its 600th anniversary last year. The strong trunk of an oak tree, rough hewn and clad with iron bands, still bars the great doors against potential mobs of students. A low portal has been cut in it to allow inspection of all strangers. The stone nearby has been scuffed by thousands of feet over six centuries—some unshod, some in
Dying
Authors: Stephen Scott
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 37: Consortium-Based Genetic Studies of Kawasaki Disease in Korea: Overview of Korean Kawasaki Disease Genetics Consortium
Authors: Jong-Keuk Lee, Young Mi Hong, Gi Young Jang, Sin Weon Yun, Jeong Jin Yu, Kyung Lim Yoon, Kyung-Yil Lee, Hong-Rang Kil, Gi Beom Kim
Journal: Circulation (2015)

In order to perform large-scale genetic studies of Kawasaki disease (KD) in Korea, the Korean Kawasaki Disease Genetics Consortium (KKDGC) was formed in 2008 with 10 hospitals. Since the establishment of KKDGC, we have collected a total of 1,198 patients’ clinical data and approximately 5 ml of blood samples per patient (for genomic DNA and plasma isolation) using standard clinical data collection forms and nation-wide networking system for blood sample pick-up. In our previous clinical risk factor analysis using collected clinical data of 478 KD patients, we found that incomplete KD, intravenous immunoglobulin (IVIG) non-responsiveness, long febrile days are major risk factors for coronary artery lesions (CALs) development, whereas low serum albumin concentration is an independent risk factor for IVIG non-responsiveness. Recently, we are re-analyzing the clinical data of all collected KD patients to evaluate the effect of age, gender, family history status, recurrence status, KD types on clinical features of KD. In addition, in our previous genome-wide association studies (GWAS) using Affymetrix SNP array 6.0 in 186 Korean KD patients and 600 healthy controls, we identified a Kawasaki disease susceptibility locus at 1p31. We also identified significant associations of coronary artery aneurysm with a variant located in KCNN2 gene and common variants in CRP gene promoter with the increased CRP levels in KD patients. Furthermore, to identify new KD susceptibility and subphenotype loci, we are performing another GWAS using Illumina Human Omni1 SNP chip with approximately 300 KD cases containing 16 cases with family history, 46 cases with recurrence, 119 cases with IVIG non-responsiveness, 52 cases with CALs (diameter &gt;5mm). Multiple subsets of KD cases will be very useful to detect loci associated with the subphenotypes of KD in GWAS data analysis. We also performed DNA microarray analysis to determine differential gene expression by in vitro immunoglobulin treatment using patient-derived B cell lines (IVIG-responders vs. IVIG-non-responders). However, we could not find any difference between B cell lines. Furthermore, a pilot study of exome sequencing of 12 KD cases was not successful in identifying causal KD susceptibility genes.
Cadaver Aortic Valve Replaces Mitral
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Bacteria Produce Hormone-Like Action
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE EMERGENCY RATION OF THE ARMY.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
FACTORS INVOLVED IN LEATHER DERMATITIS. Herman Beerman. (Arch. of Derm. and Syph., May, 1934, xxix, p. 671.)
Authors: J. M. H. M.
Journal: British Journal of Dermatology (1935)

Journal Article FACTORS INVOLVED IN LEATHER DERMATITIS. Herman Beerman. (Arch. of Derm. and Syph., May, 1934, xxix, p. 671.) Get access J. M. H. M. J. M. H. M. Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology and Syphilis, Volume 47, Issue 11, 1 November 1935, Pages 487–488, https://doi.org/10.1111/j.1365-2133.1935.tb10228.x Published: 01 November 1935
Sphygmomanometric cuff size and blood pressure recordings
Authors: G. E. Burch
Journal: JAMA (1973)

In a group of 50 adult patients, indirect blood pressure recordings were obtained with nine Velcro self-adhesive cuffs of varying widths and lengths. Ten additional patients were studied to compare direct intraarterial blood pressure recordings with recordings obtained by the auscultatory method in the same arm. The data were subjected to statistical analyses that showed that the width of the air-inflatable bladder is important and should be 12 to 14 cm. The length of the bladder contained by the cuff needs only to encircle about one half the circumference of the arm. The standard adult arm cuff with a 23 × 12.5-cm bladder is adequate for accurate indirect blood pressure determinations in an adult population. The Velcro self-adhesive cuff is preferred because of its time saving qualities and smoother application.