tbuckley/cabot-search huggingface dataset:
Incidence of Tuberculosis in Students
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tuberculosis management in Europe Recommendations of a Task Force of the European Respiratory Society (ERS), the World Health Organisation (WHO) and the International Union against Tuberculosis and Lung Disease (IUATLD) Europe Region.
Authors: G B Migliori, M C Raviglione, T Schaberg, P D Davies, J P Zellweger, M Grzemska, T Mihaescu, L Clancy, L Casali
Journal: European Respiratory Journal (1999)

The objective of tuberculosis (TB) control is the elimination of TB by stopping the transmission of the disease [1±3].This is achieved through the rapid identification and effective treatment of infectious cases [1±3].Modern anti-TB chemotherapy is based on the principle of administering properly selected standardized therapeutic schemes at proper dosage for a sufficient duration [4].Although, in several European countries, national guidelines, have been produced to standardize diagnostic and treatment procedures, as suggested by the World Health Organization (WHO) and the International Union against Tuberculosis and Lung Disease (IUATLD) [1±3], a comprehensive document focused on TB management in Europe is not available.[1, 5±7].As TB still remains a relevant public health problem in Europe [8±11], a European Task Force was established within the European Respiratory Society (ERS), involving ERS, WHO and IUATLD experts, to produce guide-lines on TB management in Europe specifically designed for specialists treating TB patients.The guidelines, which are consistent with WHO/IUATLD documents previously published in Europe, are particularly focused on standardized anti-TB treatment, treatment result monitoring and treatment in special situations.
Atlas der Haut- und Geschlechtskrankheiten zugleich ein Lehrbuch.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fourth Annual ECP Symposium on Concepts and Theories in Carcinogenesis
Journal: JNCI Journal of the National Cancer Institute (1986)

Journal Article Fourth Annual ECP Symposium on Concepts and Theories in Carcinogenesis Get access JNCI: Journal of the National Cancer Institute, Volume 76, Issue 2, February 1986, Page 362, https://doi.org/10.1093/jnci/76.2.362 Published: 01 February 1986
Multifactorial effects of AXA1125 and AXA1957 observed on markers of metabolism, inflammation and fibrosis: a 16-week randomized placebo-controlled study in subjects with non-alcoholic fatty liver disease (NAFLD) with and without type 2 diabetes (T2D)
Authors: Stephen A. Harrison, Seth J. Baum, Nadege T. Gunn, Ziad H. Younes, Anita Kohli, Rashmee Patil, Margaret J. Koziel, Harinder Chera, Jeff Zhao, Manu V. Chakravarthy
Journal: Journal of Hepatology (2020)
Risk-Taking Behaviors Among Israeli Adolescents Exposed to Recurrent Terrorism: Provoking Danger Under Continuous Threat?
Authors: Ruth Pat-Horenczyk
Journal: American Journal of Psychiatry (2007)

Objective: This study aimed to assess 1) the relationship between risk-taking behaviors and exposure to terrorism, 2) the relationship between posttraumatic symptoms and risk-taking behaviors, and 3) gender differences in the type and frequency of risk-taking behaviors and their differential associations with posttraumatic symptoms. Method: The participants were 409 Israeli adolescents 15 to 18 years of age. Exposure to terrorism was assessed with a questionnaire developed specifically for the Israeli security situation. Posttraumatic symptoms were measured with the University of California at Los Angeles Reaction Index. Functional impairment was measured with the Diagnostic Interview Schedule for Children. Risk-taking behavior—and the adolescents’ perceptions of such behavior—was assessed with a self-report questionnaire. Results: Israeli adolescents exposed to continuous threats of terrorist attacks reported high levels of risk-taking behaviors. The severity of risk-taking was associated with greater terrorism exposure. Adolescents suffering from posttraumatic symptoms reported more risk-taking behaviors than nonsymptomatic adolescents. Although there was no gender difference in the degree of exposure to terrorism, boys reported taking more risks than girls. The association between posttraumatic symptoms and risk-taking behaviors was stronger in boys than girls. Functional impairment, gender, avoidance symptoms, level of exposure, and degree of fear predicted the severity of risk-taking behaviors. Conclusions: Clinicians and educators should be aware of the strong link between posttraumatic distress and risk-taking behaviors. Risk-taking behaviors may be a manifestation of functional impairment and posttraumatic distress, especially for boys exposed to terrorism.
PS 0793-1057
Authors: J Muñoz, M Aragones, B Hernandez, M Delgado, R Gomez, M Arias, M Zamora, A Muñoz, S Tan, L Hakkaart, M Al, C Bouwmans, M Hoogendoorn, P Spronk, J Bakker, F Meurant, G Prat, S Jaffuel, M Lefevre, A Renault, J Tonnelier, E L'her, J Boles, P Mulder, R Welte
Journal: Intensive Care Medicine (2007)
Book Review Clinical Pediatrics, Volumes 19, 20 and 21. D. Appleton &amp; Company. Vol. XIX. Diseases of the Genito-Urinary System in Infancy and Childhood . By Henry F. Helmholz, M.D., Professor of Pediatrics, University of Minnesota (The Mayo Foundation); Head of Section on Pediatrics, The Mayo Clinic, Rochester, Minn.; and Samuel Amberg, M.D., Associate Professor of Pediatrics, University of Minnesota (The Mayo Foundation); Associate, Section on Pediatrics, The Mayo Clinic, Rochester, Minn.
Journal: New England Journal of Medicine (1930)
STREAM INFECTION BY CAMPERS.
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE LYMPHATIC CONSTITUTION IN IDIOPATHIC EPILEPSY.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Laboratories may face more strict controls
Authors: C. Marwick
Journal: JAMA (1988)

CONGRESS IS DRAFTING legislation that could provide stricter controls over clinical laboratories. This follows testimony in recent weeks that included allegations of laboratories' overcharging for tests, using two fee schedules (one for third-party payers and another for physicians), giving kickbacks to increase business, and pressuring technologists to screen as many as 200 Papanicolaou smears a day (the American Society for Cytotechnology recommends that no more than 70 to 90 such slides be read in a 24-hour period) as well as allowing them to take slides home to read (a violation of the Clinical Laboratory Improvement Act and Medicare regulations). These allegations were aired in front of congressmen Ron Wyden (D-Ore) and John D. Dingell (D-Mich) and senators Carl Levin (D-Mich) and William S. Cohen (R-Me). Out of them has come at least one legislative proposal, by Congressman Wyden, that includes banning solicitations for laboratory specimens, requiring annual inspections of laboratories,
CALIFORNIA'S PLAGUE LEGISLATION.
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: BMJ (1950)

MDICAL JOURNAL Javert and Stander (1943) on the basis of 27,000 births give the high figure of just 3%, but some of the malformations included were of a relatively minor character.As pointed out by Carter (1950), however, it is possible that most series based on births in hospitals give too high a figure if, as is usual, emergency admissions are not separated from the booked cases.Taking the evidence as a whole, the figure of one in forty is probably too high if what constitutes a serious abnormality is fairly strictly interpreted and if it includes only those cases in which the malformation is apparent at birth.If, however, one includes also such errors of development, abiotrophies, and constitutional abnormalities as are manifested early in life it seems a reasonable estimate and an appropriate one to quote to parents.
Fats, Cigarets and Cholesterol Discussed at Heart Meeting
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
BERLIN
Journal: JAMA (1925)

<h3>Congress of the German Society of Internal Medicine</h3><h3>PHYSIOLOGIC TESTS OF SENSIBILITY</h3> The congress of the Deutsche Gesellschaft für innere Medizin was held in Wiesbaden, April 20-23. Professor von Frey of Würzburg presented the first paper, on sensation. While vision, hearing, odor and taste have long been thoroughly studied, we know less of the other senses. Since the researches of E. H. Weber, the specificity of various kinds of perception in relation to their organs has been assumed. Thus, we recognize the sense of warmth, the sense of cold and the sense of pressure, and also a sense of power or of weight inherent in the muscles is made probable. There may be other manifestations of the skin sense. In testing sensibility by irritation of minute areas, diverse kinds of perception may be localized. On the surface of the human body, 3,500,000 pain points, 500,000 pressure points, 250,000 points especially
The US health care system in the year 2000
Authors: J. C. Goldsmith
Journal: JAMA (1986)

PREDICTING the future in an age of rapid social change is risky business. However, one thing can be confidently said about the American health care system in the year 2000: most of its ingredients—the patients, the professionals, the strains of scientific inquiry and technological development, and much of the capital—are already present. Scientific and technological developments have been extensively reviewed elsewhere<sup>1</sup>; this article will speculate on the impact of demographics, changing financing systems, and medical care organization in shaping the future American health care provision system. <h3>Demographics</h3> Barring a major war or natural catastrophe, approximately three fourths of the population to be served at the dawn of the 21st century is already living (unpublished data, National Center for Health Statistics, 1984).<sup>2</sup>The US population currently alive may account for as much as 90% of the health care demand encountered by the early part of the next century. By
Extracorporeal shock-wave lithotripsy for upper urinary tract calculi. One year's experience at a single center
Authors: R. A. Riehle
Journal: JAMA (1986)

Four hundred sixty-seven patients with symptomatic upper urinary tract calculi underwent extracorporeal shock-wave lithotripsy (ESWL) at The New York Hospital-Cornell Medical Center during the first year. Ninety-five percent of stones were completely treated with one ESWL session. An analysis of 300 treatments revealed that the overall stone-free rate (success) three months after treatment was 75% The stone-free rate for patients with renal pelvic calculi less than or equal to 20 mm in diameter was 91%. Individual patient stone-free rates depended on stone size (burden), position, composition, and quality of disintegration. Two percent of treatments failed to disintegrate the targeted stone. Complications were minimal. Seven percent of treatments were followed by a secondary endoscopic procedure to facilitate complete stone passage, and 23% of treatments were preceded by cystoscopy with ureteral stent placement or manipulation of stones. Combined therapy utilizing percutaneous surgery or multiple sequential ESWL treatments is necessary for complex stones, and ureteroscopy or basket extraction remains the treatment of choice for distal ureteral calculi. (<i>JAMA</i>1986;255:2043-2048)
Clinical outcomes following selection of human preimplantation embryos with time-lapse monitoring: a systematic review
Authors: Daniel J. Kaser, Catherine Racowsky
Journal: Human Reproduction Update (2014)

BACKGROUNDTime-lapse monitoring (TLM) has emerged as a novel technology to perform semi-quantitative evaluation of embryo morphology and developmental kinetics in assisted reproduction. While this method has already been introduced into clinical practice in many laboratories, it is unclear whether it adds value to conventional morphology. Most studies only report blastocyst formation as the primary end-point. The aim of this systematic review is to provide a critical evaluation of the available studies that report clinical outcomes following embryo selection with TLM.
Abstract 304: Molecular Mechanisms of Electrically-induced Cardioprotection
Authors: Anne E Roessler, Kristin Luther, Xiaoping Ren, Yang Wang, Zilong Shen, Qing Miao, W. Keith Jones
Journal: Circulation Research (2017)

Ischemic preconditioning (IPC) is a well-characterized cardioprotective phenomenon involving multiple brief, non-lethal ischemic episodes to the heart. Remote ischemic preconditioning (RIPC) elicits cardioprotection via repetitive ischemia and reperfusion to a distant vascular bed, organ, or limb. A non-ischemic, nociceptive stimulus in distant tissues can result in the most powerful cardioprotection reported - an 80% decrease in infarct size - called remote nociceptor-induced cardioprotection (NIC). Electrically induced cardioprotection via electrical stimulation with electroacupuncture needles (EA) or skin patches (ES) on the abdomen may be a clinically feasible way to induce NIC. A 5 volt, 15 minute electrical stimulus applied as either preconditioning or postconditioning reduces infarct size in a mouse surgical model of myocardial infarction. This study’s objective is to determine the molecular mechanism of electrically-induced NIC. Our previous work shows that IPC requires upregulation and post-transcriptional regulation of heat shock proteins (HSPs), which act in unity to assist in protein folding, repair, and degradation following myocardial injury. However, Western blotting and PCR revealed non-significant changes in HSP mRNA and protein relative to sham, which were inconsistent with the large, significant increases in HSPs observed after IPC. Studies using mice with a genetic deletion of HSP70.1 revealed that this heat shock protein is not required for protection. The transcription factor NF-κB regulates many cardioprotective genes in the heart after IPC, including, but not limited to, heat shock proteins. Based on our work in IPC, we hypothesize that electrical stimulation of the skin is cardioprotective via a unique induction of NF-κB-dependent genes. Pharmacological and genetic inhibition of NF-κB were utilized to evaluate the role of this transcription factor in electrically-induced cardioprotection. Deep sequencing studies are in progress to delineate the presence and quantity of additional transcripts that may be involved in electrically-induced cardioprotection. Future investigations will address the neurobiology of electrically-induced cardioprotection via skin stimulation.
Abstract 4617: <i>In vivo</i> efficacy focused data collection and gaps for preclinical anticancer drug evaluation
Authors: Taiping Chen, Xiaoqin Sun, Tingting Li
Journal: Cancer Research (2019)

Abstract Even though most anticancer drugs have been initially screened, investigated, and evaluated with variety of in vitro platforms, gaps between preclinical nominated candidate and clinical acceptable approval of final drug remain a big challenge for biotech companies all over the world. It is a highly demanding task to establish various animal models which can closely mimic human tumorigenesis in preclinical drug evaluation. Here we summarize several in vivo efficacy models to discuss on various applications in the data collection and interpretation. Currently available models include traditional cancer cell derived xenograft (CDX), patient derived xenograft (PDX), immune component murine tumor models (syngeneic and human gene knock-in), and orthotopic tumor models. Based on different drug mechanisms appropriate models will be initially selected with certain rationale. In order to understand the in vivo mechanisms of action (MOA) and drug target relevance, biomarker profiling and pharmacodynamic changes will be investigated with IHC, and/or FACS analysis particularly when the test articles display clear efficacious responses. Some representative data will be presented to demonstrate that in vivo efficacy will be the key endpoint for further analysis and clinical trial support. Small and large molecules of targeted drugs, antibody drug conjugate (ADC), immune checkpoint therapeutics will be included in the discussion. In sum, the approaches of in vivo data collection here are feasible to support many drug candidates to be evaluated to fill the gaps in the clinical drug development. Citation Format: Taiping Chen, Xiaoqin Sun, Tingting Li. In vivo efficacy focused data collection and gaps for preclinical anticancer drug evaluation [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4617.