tbuckley/cabot-search huggingface dataset:
Treatment of Epistaxis
Authors: David L. Pierce, Werner D. Chasin
Journal: New England Journal of Medicine (1962)

THIS article presents data collected at a specialty hospital regarding epistaxis and an effective means of treating it. Our study covers the period from January, 1959, through December, 1960. During this time 1320 patients with epistaxis were treated in the Emergency Ward of the Massachusetts Eye and Ear Infirmary, and 132 of these were admitted for inpatient care.Locating the Site of BleedingFor practical purposes, the supplies needed include the following: a good source of light and a head mirror; a nasal speculum and Pilling suction tip; a cautery (we prefer small beads of chromic acid on ear wires); . . .
Sunday Mournings
Authors: Eric Pfeiffer
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Immediate early detection of urokinase receptor after partial hepatectomy and its implications for initiation of liver regeneration*1
Authors: W MARS
Journal: Hepatology (1995)

Hepatocyte growth factor (HGF), also known as scatter factor, is believed to play a primary role in liver regeneration. HGF is produced in an inactive single-chain form that can be cleaved in vitro to the active two-chain form by tissue-type and urokinase-type plasminogen (PLG) activators (tPA and uPA). We have now documented the de novo appearance of active uPA in livers from male Fischer F344 rats that underwent 70% partial hepatectomy (PHx) as early as 1 minute after surgery. Western blot analyses of protein extracts from liver remnants that were obtained immediately after surgery and periodically until 24 hours after PHx indicate that the quantity of uPA remains fairly constant in PHx samples. In contrast, the uPA receptor (uPAR) dramatically increases, beginning within 1 minute after PHx. This results in enhanced activity of uPA, as seen by direct zymography on cryostat sections. The uPA present in remnant liver homogenates from rats that underwent PHx is the primary agent that cleaves single-chain HGF to its two-chain form, because cleavage can be prevented when antibody against uPA is included in the liver homogenates. Furthermore, heterodimeric HGF, which is not present in normal liver, increases in the liver remnants from rats that underwent PHx, correlative to uPAR. The presence of active uPA is one of the earliest responses yet documented after PHx. These findings imply that both uPA and uPAR are involved in activating endogenous HGF in the regenerating livers of animals that underwent PHx.
Underage drinking
Authors: J. P. Callan
Journal: JAMA (1993)

<h3>In Reply.</h3> —Dr Callan notes that underage drinking has decreased slightly over the last 10 years (from greater than 93% of high school seniors in 1980 to 88% in 1991). Of course, any reduction is welcome. However, the author seems to have missed the landscape by looking at a leaf. Underage drinking is still a mysterious health problem shrouded in fantasy, hearsay evidence, ignorance, and indifference. Parents, educators, and medical professionals desperately require hard data to answer the many vital questions about underage drinking, especially about what beverages are consumed, the motivations for drinking, the effect of advertising, and how to craft successful interventions. We need comprehensive, accurate, and relevant information. The eight invaluable and illuminating studies by the Department of Health and Human Services Office of Inspector General,<sup>1-8</sup>conducted at the request of Surgeon General Antonia C. Novello, were designed to search out the available data, fill in
BACTERIOLOGY OF LOBAR PNEUMONIA IN TYPHOID FEVER.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hysteria and Depression: The Frequency and Significance of Hysterical Personality Features in Hospitalized Depressed Women
Authors: AARON LAZARE, GERALD L. KLERMAN
Journal: American Journal of Psychiatry (1968)

Lack of clarity of definition has contributed to the difficulty in studying the phenomena of hysteria and depression. The authors, by devising a reliable measure for the hysterical personality and by using the Hamilton Rating Scale for Depression, have attempted to study the frequency and significance of hysterical personality features in hospitalized depressed women.
Clinical decision making: theory vs practice
Journal: JAMA (1990)

<h3>To the Editor.—</h3> Dr Eddy<sup>1,2</sup>must be praised for seeking to define, or perhaps divine, a rational methodology to control and fine-tune practice policies, for patterns of practice are at the root of the inexorable and seemingly uncontrollable rise in this nation's health costs. In a private practice, fee-for-service system, it is impossible to ignore the fact that physicians will perform or request the services that maximize their income within the broad limits of legal, ethical, scientific, and clinical parameters. All practicing physicians are aware of and engage in useless and usually harmless activities, without which the patient's health would be unaffected. The litany of such practices is endless and cuts across all medical and surgical disciplines. The vast majority of such practices involves gray areas. If, using the global subjective judgment approach (Dr Eddy's term) to monitor a procedure, a panel unanimously agrees that it is unnecessary for
EXPERIMENTS ON ARTIFICIAL HEARTS
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Challenges Facing Family Practice and Primary Care
Authors: Michael L. O'Neal
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Computerized tomography of the musculoskeletal system
Authors: E. M. Levinsohn
Journal: JAMA (1980)

THE VALUE of computerized tomography (CT) in evaluating cranial, thoracic, abdominal, and pelvic abnormalities is well accepted.<sup>1</sup>The use of CT in diagnosing disorders of the musculoskeletal system is similar to its application to other regions of the body. In those anatomic areas where muscles and neurovascular structures are relatively large, CT provides an accurate tool in assessing anteroposterior relationships. The availability of the opposite extremity to serve as a control is an added advantage. The axial plane is particularly useful in assessing orthopedic disorders of the hip, thigh, shoulder, and sternoclavicular joint. Around joints, where a curving plane may not be optimally visualized on either the anteroposterior or lateral roentgenogram, the axial projection is particularly valuable.<sup>2</sup>Although plain roentgenograms provide better bony detail than CT, the medullary space is better seen with CT. Computerized tomography is more sensitive to small differences in x-ray absorption than conventional films.
Taking control of cancer: Why women are choosing mastectomy.
Authors: Andrea Marie Covelli, Nancy N. Baxter, Margaret Fitch, Frances Catriona Wright
Journal: Journal of Clinical Oncology (2013)

108 Background: Rates of both unilateral (UM) and contralateral prophylactic mastectomy (CPM) for early stage breast cancer (ESBC) have been increasing since 2003. More extensive surgery is not a benign procedure without the risk of complications. Studies suggest that the increase is due to women choosing UM and CPM; we do not know what factors are influencing the choice for more extensive surgery. Methods: We conducted a qualitative study using grounded theory to identify factors for the choice of mastectomy. Purposive sampling was used to identify women across the Toronto Area (Ontario, Canada), who were suitable candidates for breast conserving surgery (BCS) but underwent UM or CPM. Data were collected through semi-structured interviews. Constant comparative analysis identified key concepts and themes. Results: Data saturation was achieved after 29 in-person interviews. 12 interviewees were treated at academic cancer centers, 6 at an academic non-cancer center and 11 at community centers. 15 women underwent UM; 14 underwent UM+CPM. Median age was 55. ‘Taking control of cancer’ was the dominant theme. Fear of breast cancerwas expressed at diagnosisand remains throughout decision making. Fear translates into the overestimated risk of local recurrenceand contralateral cancer. Despite discussion of the equivalence of BCS and UM, patients chose UM due to fear of recurrence and misperceived survival advantage. Similarly, patients chose CPM to eliminate the risk of contralateral cancer and misperceived survival advantage. Women were actively trying to Control Outcomes, as more surgery was seen as greater control. Conclusions: Women seeking UM and CPM for treatment of their early stage breast cancer manage their fear of cancer by undergoing more extensive surgery which in turn drives mastectomy rates. It is important to understand this process so that we may improve our ability to discuss issues of importance to women and facilitate informed decision-making.
On the utility of growth curves
Authors: V. C. Vaughan
Journal: JAMA (1992)

In this issue ofThe JOURNAL, Yip et al<sup>1</sup>describe the changes that have taken place in a decade (1980 through 1989) in the birth weight and early childhood growth of children of low-income immigrant families from Southeast Asia. While Asian See also p 937. immigrant infants and young children showed a marked shift in growth status toward the reference standards of the National Center for Health Statistics (NCHS),<sup>2</sup>during this same period the status of black, white, and Hispanic subjects from the same low-income population remained essentially unchanged. Data were collected through the Centers for Disease Control Pediatric Nutrition Surveillance System, which monitors the status of children who are receiving services through certain public health and nutrition programs (in major part through the Special Supplemental Food Program for Women, Infants, and Children). The data show a fall in incidence of low birth weight (less than 2500 g)
Gerald Donaldson
Authors: P. J. Ward, E. L. Holland
Journal: BMJ (2010)

<h3>Objective</h3> The aim of this study was to evaluate the role of pulmonary resection in the management of high-risk gestational trophoblastic neoplasia (GTN). <h3>Methods</h3> Patients who underwent pulmonary resection as part of their treatment for chemotherapy-resistant high-risk GTN from 1986 and 2014 were retrospectively analyzed. All patients had received 1 or more multiagent chemotherapy regimens preoperatively. Patient and disease characteristics were evaluated with respect to outcome. <h3>Results</h3> Fifteen (26%) of 58 patients treated for high-risk GTN underwent pulmonary resection with curative intent. Mean age of patients was 29 years (range, 19–37 years). International Federation of Gynecology and Obstetrics stage was III in 12 and IV in 3. International Federation of Gynecology and Obstetrics scores ranged from 5 to 20 (mean, 10). Antecedent pregnancy was nonmolar in 11 patients (73%). Adjuvant surgical procedures other than pulmonary resection were performed in 8 patients (53%). Preoperative chemotherapy regimens ranged from 1 to 10 (median, 4) and courses numbered from 2 to 32 (median, 14). Preoperative human chorionic gonadotropin (hCG) levels ranged from 2 to 2786 mIU/mL (median, 177 mIU/mL). Pulmonary wedge resections or lobectomies were performed via video-assisted thoracoscopic surgery (11) or thoracotomy (4). Two patients underwent pulmonary resections on 2 separate occasions. No patient had complications as a result of these procedures. Eleven patients (73%) were cured. In these 11 patients, hCG levels decreased to less than 2 mIU/mL within 6 to 52 days (mean, 22 days) postoperatively. <h3>Conclusions</h3> Pulmonary resection of chemotherapy-resistant GTN was an important component of treatment in 26% of high-risk patients, 73% of whom were cured. Ideal candidates have disease isolated to the lungs and low hCG levels.
Abdominal Surgery
Authors: Arthur W. Allen, Claude E. Welch
Journal: New England Journal of Medicine (1950)

THE great volume of literature devoted to abdominal surgery continues unabated, and it is therefore possible, in this brief survey, to include only the salient features of articles that are of great importance or of wide interest. During the past year, surgeons generally have been concerned with more accurate appraisal of the value of established procedures rather than the introduction of new operations. Of particular interest, in this respect, are the management of acute massive gastrointestinal hemorrhage, the treatment of the various lesions of the pancreas and the surgical therapy of polyps and cancer of the colon and rectum. These . . .
Corticosteroid treatment in systemic lupus erythematosus. Survival studies
Authors: J. D. Urman
Journal: JAMA (1977)

Survival rates of two groups of corticosteroid-treated patients with systemic lupus erythematosus (SLE) have been compared using life-table analysis. Group 1 consists of 209 SLE patients studied in New York City between 1957 and 1968; group 2 consists of 156 SLE patients studied in Connecticut between 1968 and 1976. A similar percentage of patients in each group was followed up closely by one of us. The five-year survival rate for group 1 was 70%, compared with 93% for group 2. The improved survival could not be explained by differences in racial composition, incidence of CNS manifestations, or incidence of severe renal disease. The markedly improved survival may be due to several factors, including a generally better understanding of the disease and the recent use of newer antibiotics. The management of the two groups was similar, except that group 2 patient's conditions were managed not only on the basis of clinical evidence of disease activity but also on the basis of the serum complement (C3) level and on the basis of the level of antibody to native DNA. The data suggest that the use of such serologic values may lead to improved survival. (<i>JAMA</i>238:2272-2276, 1977)
BOOK REVIEWS
Authors: G. WILDING
Journal: JNCI Journal of the National Cancer Institute (1992)

Journal Article BOOK REVIEWS Get access Incidental Carcinoma of the Prostate J. E. Altwein , P. Faul , W. Schneider , eds. Berlin : Springer-Verlag , 1991 , 272 pp., illus. $89.00. ISBN 3-540-53225-0 GEORGE WILDING GEORGE WILDING Department of Human Oncology University of Wisconsin Comprehensive Cancer Center K4/666 CSC600 Highland Ave. Madison WI 53792 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 84, Issue 13, 1 July 1992, Pages 1041–1042, https://doi.org/10.1093/jnci/84.13.1041-a Published: 01 July 1992
Atlas and Epitome of the Nervous System and Its Diseases.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Digitalis Intoxication
Authors: ARTHUR C. DEGRAFF
Journal: Circulation (1954)

Since 1946, when the Veterans Administration Hospital, Kingsbridge Road, Bronx, New York City, cxame under the supervision of the Deans Committee of the five medical colleges in New York City, conferences have been held each Wednesday afternoon by the Cardiovascular Service. The conference of July 22, 1953, on "Digitalis Intoxication" was recorded and transcribed for publication in this Journal. Participating in that conference were the following: DR. ARTHUR C. DEGRAFF, Senior Consultant in Medicine, DR. BERNARD STRAUS, Director of the Medical Service, DR. LOUIS A. KAPP, Chief of the Cardiovascular Service, DR. WALTER NEWMAN, Assistant Chief of the Cardiovascular Service, DR. LOUIS F. BISHOP, Attending Consultant, DR. O. ALAN ROSE, Attending Consultant, DR. J. B. SCHWEDEL, Attending Consultant, DR. FREDERICK LANDAU, Attending Consultant, DR. HARRY FEIN, Attending Consultant, DR. ARTHUR F. HEYL, guest physician, and resident physicians on the Cardiovascular Service.
Criteria for Retirement: A Report of a National Conference on Retirement of Older Workers
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal