tbuckley/cabot-search huggingface dataset:
Precis de Manuel Operatoire.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Issue Information
Authors: J Bousquet, C Akdis, M Jutel, C Bachert, L Klimek, I Agache, I Ansotegui, A Bedbrook, S Bosnic-Anticevich, G Canonica, T Chivato, A Cruz, W Czarlewski, S Giacco, H Du, J Fonseca, Y.-D Gao, T Haahtela, K Hoffmann-Sommergruber, J.-C Ivancevich, N Khaltaev, E Knol, P Kuna, D Larenas-Linnemann, J Mullol, R Naclerio, K Ohta, Y Okamoto, L O'mahony, G Onorato, N Papadopoulos, O Pfaar, B Samolinski, J Schwarze, S Toppila-Salmi, M.-T Ventura, A Valiulis, A Yorgancioglu, T Zuberbier, R Pawankar, M Sokolowska, Z Lukasik, D Akdis, M Akdis, W Barcik, H Brough, T Eiwegger, A Eljaszewicz, S Eyerich, W Feleszko, C Gomez-Casado, J Janda, R Jiménez-Saiz, I Kortekaas Krohn, A Kothari, J Makowska, M Moniuszko, H Morita, K Nadeau, C Ozdemir, I Pali-Schöll, O Palomares, F Papaleo, M Prunicki, C Schmidt-Weber, A Sediva, M Shamji, G Tramper-Stranders, W Van De Veen, E Untersmayr, M De, Lima Moreira, M Souter, Z Chen, L Loh, J Mccluskey, D Pellicci, S Eckle, Ige Past, P Biologics, A Guntern, C Riggioni, P Comberiati, M Giovannini, M Alves-Correia, J Antó, A Arcolaci, A Azkur, D Azkur, B Beken, C Boccabella, H Breiteneder, D Carvalho, L De Las Vecillas, Z Diamant, I Eguiluz-Gracia, W Fokkens, F Hannachi, S Johnston, A Karavelia, B Moya, R O'hehir, M Sanak, M Torres, M Van Zelm, D Wang, L Zhang, S Bonini, G Maltese, B Callejas-Díaz, G Fernandez, M Fuentes, A Martínez-Antón, I Alobid, J Roca-Ferrer, C Picado, V Tubita, A Ariza, R Fernández-Santamaría, X Meng, M Salas, M Ogese, A Tailor, G Bogas, D Naisbitt, M Aparicio-Soto, F Riedel, M Leddermann, P Bacher, A Scheffold, H Kuhl, B Timmermann, D Chudakov, S Molin, M Worm, G Heine, H.-J Thierse, A Luch, K Siewert, H Vroman, D Van Uden, I Bergen, J Van Hulst, M Lukkes, G Van Loo, B Clausen, L Boon, B Lambrecht, H Hammad, R Hendriks, M Kool, C.-L Wang, L Chen, Z.-C Pan, J Wang, Z.-A Yunis, Y Chen, S.-T Zhang, X.-Y Hu, R.-F Xu, D Zhu, Z Yu, M Suprun, R Getts, G Grishina, A Tsuang, M Suárez-Fariñas, H Sampson, A Bilò, M Corsi, E Martini, F Penza, D Grippo, E Nettis, V Patella, C Lombardo, A Detoraki, L Macchia, E Leo, M Carbonara, L Bonzano, S Sindher, S Alkotob, M Shojinaga, H Bahnson, S Chan, G Lack, D Leung, J Guo, Y Song, A Saiganesh, B Hales, A Bosco, P Le Souëf, G Zhang, A Karsonova, K Riabova, S Villazala-Merino, R Campana, V Niederberger, J Eckl-Dorna, R Fröschl, T Perkmann, Y Zhernov, O Elisyutina, E Fedenko, M Khaitov, D Fomina, E Beltiukov, M Van Hage, H Grönlund, R Valenta, A Karaulov, M Curin, G Pouessel, J Dubus, S Lejeune, H Béhal, G Noël, E Beaudouin, A Deschildre, J Corriger, P Bolcas, E Brandt, B Ruff, M Kalra, G Khurana Hershey, T Shirai, T Akamatsu, K Hirai, H Watanabe, K Tamura, Y Kishimoto, M Saigusa, D Di Bona, E Minenna, A Lovecchio, D Paolino, M Nizi, M Albanesi, E Ridolo, M Caiaffa, P Gajdanowicz, D Van Elst, S Smolińska, A Kettner, T Schmidtmann, J Bopp, K Brieger, M Abdel-Aziz, R De Vries, A Lammers, B Xu, A Neerincx, S Vijverberg, Y Dagelet, A Kraneveld, U Frey, R Lutter, P Sterk, A Maitland-Van Der Zee, A Sinha, R Jimenez-Saiz
Journal: Allergy (2020)

Effectiveness of
Better Nanoparticle Targeting with P-Selectin
Journal: Cancer Discovery (2016)

A study in mice indicates that the adhesion molecule P-selectin, which is expressed on the endothelium during inflammation, may serve as a target for the delivery of drug-filled nanoparticles to tumors. Antitumor efficacy was achieved in several mouse models of cancer, and the researchers successfully used this approach even against noninflammatory tumors, by first using ionizing radiation to trigger P-selectin's expression on the tumor vasculature.
Calcium
Authors: Marc J. Straus
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Response
Authors: ARTHUR SCHATZKIN, LAURENCE S. FREEDMAN, SANFORD M. DAWSEY, ELAINE LANZA
Journal: JNCI Journal of the National Cancer Institute (1994)

Journal Article Response Get access ARTHUR SCHATZKIN, ARTHUR SCHATZKIN Search for other works by this author on: Oxford Academic PubMed Google Scholar LAURENCE S. FREEDMAN, LAURENCE S. FREEDMAN Search for other works by this author on: Oxford Academic PubMed Google Scholar SANFORD M. DAWSEY, SANFORD M. DAWSEY Search for other works by this author on: Oxford Academic PubMed Google Scholar ELAINE LANZA ELAINE LANZA Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 86, Issue 21, 2 November 1994, Pages 1648–1649, https://doi.org/10.1093/jnci/86.21.1648-a Published: 02 November 1994
Stroke following chiropractic manipulation of the spine
Authors: R. G. Miller
Journal: JAMA (1974)

STROKE has been previously described as a complication of chiropractic manipulation of the head and neck. The reported cases are notable in two respects. First, the affected patients are predominantly young (under 40 years of age) and have no demonstrable coexisting vascular disease. Second, premonitory symptoms of vertebrobasilar ischemia during neck manipulation were simply not recognized as an absolute contraindication to further mechanotherapy. We wish to reemphasize this avoidable syndrome. <h3>Report of Cases</h3><h3>Case 1.—</h3> A 52-year-old woman complained of weakness on the left side of 24 hours' duration. One month earlier she had begun a series of chiropractic manipulations because of recurrent neck pain that had started after minor injury ten years before. During several of these treatments, she experienced transient vertigo associated with nausea, blurred vision, and scintillating scotomata without loss of vision or headache. Near the end of her last treatment, following a painful rotation of the
Myelodysplastic Syndromes
Authors: Mario Cazzola
Journal: New England Journal of Medicine (2020)

MDS are clonal hematopoietic disorders involving morphologic defects and peripheral-blood cytopenias, with a risk of progression to acute myeloid leukemia. Except for del(5q) MDS, which is responsive to lenalidomide, these disorders are largely managed with supportive care.
Phase I Study of Toremifene in Patients With Advanced Cancer
Authors: John T. Hamm, Douglas C. Tormey, Peter C. Kohler, Daniel Haller, Mark Green, Irving Shemano
Journal: Journal of Clinical Oncology (1992)

In the report entitled "Phase I Study of Toremifene in Patients With Advanced Cancer" by Hamm et al (J Clin Oncol 9:2036–2041, 1991), the chemical structure "R''' " for toremifene, N-desmethyltoremifene, and 4-hydroxytoremifene should have been "R''' = CL," and the following report should have been referenced: Kohler PC, Hamm JT, Wiebe VJ, et al: Phase I study of the tolerance and pharmacokinetics of toremifene in patients with cancer. Breast Cancer Res Treat 16:19-26, 1990
Genetic Studies on Lung Tumor Susceptibility and Histogenesis in Mice
Authors: Alvin M. Malkinson
Journal: Environmental Health Perspectives (1991)

The probability that a mouse develops a pulmonary tumor, as well as the structure of that tumor, are dependent on several genes. Three pulmonary adenoma susceptibility (pas) genes predispose some inbred strains to develop lung tumors, even in the absence of carcinogen exposure, and cause others to be resistant. One pas gene is K-ras, which may also be overexpressed in these tumors in a mutated form capable of transforming cells. Mice with activated Ha-ras transgenes override the resistant pas alleles and are born with lung cancer. Susceptible strains have a higher turnover rate of alveolar type II and bronchiolar Clara cells, those cells from which lung tumors arise, than more resistant strains. A high precursor cell turnover rate correlates with a propensity to neoplasia in other animal models as well, possibly due to low concentrations of endogenous growth regulatory molecules such as corticosterone and protein kinase C (PKC). Neoplastic lung epithelial cells are relatively resistant to glucocorticoids and have low PKC levels. A set of genes other than the pas genes governs the response to tumor modulation by butylated hydroxytoluene (BHT). The genes that determine whether lung tumor multiplicity is enhanced by chronic BHT exposure may regulate the ability to hydroxylate BHT at a tert-butyl position to form BHT-OH, a metabolite with greater tumor-promoting potency than BHT. Inbred and recombinant inbred strain variations in adenoma growth patterns indicate that another set of genes, which we have designated pah for pulmonary adenoma histogenesis, may determine which cell type becomes neoplastic and whether adenomas will undergo malignant conversion.
Expression of a rat liver phosphatidylcholine translocator in Xenopus laevis oocytes
Authors: G Kullak-Ublick
Journal: Hepatology (1996)

A phospholipid translocating protein from rat liver has been expressed in Xenopus laevis oocytes. Injection of oocytes with total rat liver messenger RNA (mRNA) resulted in the function expression of saturable uptake of the water soluble phophatidylcholine derivative L-alpha- dibutyroylglycero-3-phophatidylcholine (diC4PC), Kinetic studies revealed an apparent Km value of approximately 10 mmol/L, which is similar to the value previously obtained in isolated rat liver canalicular plasma membrane vesicles for an adenosine triphosphate (ATP)-independent phosphatidylcholine translocator. Size fractionation of total rat liver mRNA yielded an active mRNA species between 1.8 and 2.6 kb, that stimulated the expressed phophatidylcholine uptake activity approximately fivefold as compared with differently sized mRNA subfractions. This active mRNA size class is too small to code for the mdr2 P-glycoprotein, which has been suggested to function as an ATP- dependent canalicular phosphatidylcholine translocator. Hence, the data indicate that there are at least two separate polypeptides involved in phospholipid translocation from hepatocytes into bile. (Hepatology 1996 May;23(5):1254-9)
Nonalcoholic Steatohepatitis
Authors: S G Sheth, F D Gordon, S Chopra
Journal: Annals of Internal Medicine (1997)

Objective: To determine the clinical relevance of nonalcoholic steatohepatitis (NASH) and to review the available literature on the epidemiology, clinical features, histology, pathogenesis, clinical course, and management of this condition. Data Sources: Pertinent articles in English identified through a MEDLINE search (1966 to the present) and the bibliographies of relevant articles. Study Selection: All studies, including case reports, evaluating the salient features and clinical profile of NASH. Data Extraction: Data were selected from all articles that fit the study selection criteria. Data Synthesis: Nonalcoholic steatohepatitis is a distinct clinical entity characterized by elevated plasma liver enzyme levels and liver biopsy findings that are identical to those seen in alcoholic hepatitis; patients with NASH, however, do not consume alcohol in quantities known to cause liver injury. Patients with NASH are typically obese, middle-aged women with asymptomatic hepatomegaly who are diabetic or hyperlipidemic and present with an unrelated medical problem. Analysis of liver biopsy specimens is the cornerstone of diagnosis; hepatic morphologic findings range from mild fatty degeneration and inflammation to cell degeneration, fibrosis, and cirrhosis with or without the presence of Mallory hyaline bodies. Elevated levels of free fatty acids in the liver are thought to be responsible for the development of steatohepatitis. Although NASH is most often a benign disease with an indolent course, patients with this condition occasionally develop cirrhosis, portal hypertension, and hepatic failure. In some cases, NASH may be reversed with weight reduction. Conclusion: Nonalcoholic steatohepatitis is an important differential diagnosis for asymptomatic patients with chronically elevated plasma liver enzyme levels, especially if obesity, diabetes, or hyperlipidemia are present. Analysis of liver biopsy specimens is necessary for diagnosis and must be done in all patients with unexplained abnormal liver function and negative results on a noninvasive workup. Prognosis is good in most patients. The precise role of weight reduction and ursodeoxycholic acid therapy in the favorable alteration of the natural history of this disorder needs to be addressed in large, well-controlled studies.
Antibacterial Chemotherapy
Authors: Avram Goldstein
Journal: New England Journal of Medicine (1949)

Resistance Priority for demonstration of the resistance of micro-organisms to specific drugs goes to Ehrlich,153 154 155 who was able to isolate strains of trypanosomes resistant to three distinct drug classes. Resistance, in his experiments, was shown to arise by repeated passage through low concentrations in vitro or in vivo, to be permanent once established and to be specific for each class of drug. Thus, organisms made resistant to triphenylmethane dyes remained sensitive to azo dyes and organic arsenicals.Ehrlich foresaw that drug fastness was to prove a major clinical stumbling block and proposed the only two means available for avoiding the . . .
THE RÔLE OF DIET AND EXERCISE IN ANTISYPHILITIC TREATMENT
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Conversion of failed transjugular intrahepatic portosystemic shunt (TIPS) to distal splenorenal shunt (DSRS) in childs A/B cirrhotics : Departments of Surgery and Medicine, Emory University School of Medicine, Atlanta, GA
Journal: Hepatology (1995)

Background & Aims: Variceal bleeding refractory to medical treatment with β-blockers and endoscopic therapy can be managed by variceal decompression with either surgical shunts or transjugular intrahepatic portal systemic shunts (TIPS). This prospective randomized trial tested the hypothesis that patients receiving distal splenorenal shunts (DSRS) would have significantly lower rebleeding and encephalopathy rates than TIPS in management of refractory variceal bleeding. Methods: A prospective randomized controlled clinical trial at 5 centers was conducted. One hundred forty patients with Child–Pugh class A and B cirrhosis and refractory variceal bleeding were randomized to DSRS or TIPS. Protocol and event follow-up for 2–8 years (mean, 46 ± 26 months) for primary end points of variceal bleeding and encephalopathy and secondary end points of death, ascites, thrombosis and stenosis, liver function, need for transplant, quality of life, and cost were evaluated. Results: There was no significant difference in rebleeding (DSRS, 5.5%; TIPS, 10.5%; P = .29) or first encephalopathy event (DSRS, 50%; TIPS, 50%). Survival at 2 and 5 years (DSRS, 81% and 62%; TIPS, 88% and 61%, respectively) were not significantly different (P = .87). Thrombosis, stenosis, and reintervention rates (DSRS, 11%; TIPS, 82%) were significantly (P < .001) higher in the TIPS group. Ascites, need for transplant, quality of life, and costs were not significantly different. Conclusions: DSRS and TIPS are similarly efficacious in the control of refractory variceal bleeding in Child–Pugh class A and B patients. Reintervention is significantly greater for TIPS compared with DSRS. Because both procedures have equivalent outcomes, the choice is dependent on available expertise and ability to monitor the shunt and reintervene when needed.
Collected Papers on Mechano-Therapeutics.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Correction
Journal: BMJ (1921)

m -_D_ _A L_As, owing to printing difictulties, the JOURNAL mstst be sent to pres ea-lier tlhant hitherto, it is essential that commnunications intended Jor thLe current issue shouild be received by the first post on Cl 'uesday, and lenigthy docuen7leits on M11onday.
Gender Differences in Time Spent on Parenting and Domestic Responsibilities
Authors: Reshma Jagsi
Journal: Annals of Internal Medicine (2014)

Letters7 October 2014Gender Differences in Time Spent on Parenting and Domestic ResponsibilitiesReshma Jagsi, MD, DPhilReshma Jagsi, MD, DPhilFrom University of Michigan, Ann Arbor, Michigan.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L14-5019-7 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:We appreciate the insights shared by the authors of these letters and thank them for providing such rich and vivid examples from women physicians' lived experiences to complement the data that we presented. We also appreciate the editors' decision to publish these letters, which reflects their clear commitment to stimulate the sort of healthy discourse and debate that characterize the academic enterprise at its best. We, like the authors of these letters, believe that our findings are a sobering indication of powerful societal constraints on women's choices even today. However, we are heartened by growing recognition of these ... Author, Article, and Disclosure InformationAuthors: Reshma Jagsi, MD, DPhilAffiliations: From University of Michigan, Ann Arbor, Michigan.Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M13-0974. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoA Woman Physician-Researcher's Work Is Never Done Molly Cooke and Christine Laine Gender Differences in Time Spent on Parenting and Domestic Responsibilities by High-Achieving Young Physician-Researchers Shruti Jolly , Kent A. Griffith , Rochelle DeCastro , Abigail Stewart , Peter Ubel , and Reshma Jagsi Gender Differences in Time Spent on Parenting and Domestic Responsibilities Ann Danoff Gender Differences in Time Spent on Parenting and Domestic Responsibilities Toni Martin Gender Differences in Time Spent on Parenting and Domestic Responsibilities Dena E. Rifkin , Nisha Bansal , and Esther K. Choo Gender Differences in Time Spent on Parenting and Domestic Responsibilities Molly Cooke and Christine Laine Gender Differences in Time Spent on Parenting and Domestic Responsibilities Molly Cooke and Christine Laine Gender Differences in Time Spent on Parenting and Domestic Responsibilities Dena E. Rifkin , Nisha Bansal , and Esther K. Choo Gender Differences in Time Spent on Parenting and Domestic Responsibilities Toni Martin Gender Differences in Time Spent on Parenting and Domestic Responsibilities Ann Danoff Metrics Cited byOvercoming COVID-19Sex Differences in Achievement and Faculty Rank in Academic Infectious DiseasesAddressing Gender Inequality in Our Disciplines: Report from the Association of Pulmonary, Critical Care, and Sleep Division Chiefs 7 October 2014Volume 161, Issue 7Page: 534KeywordsDisclosureSexual identity ePublished: 7 October 2014 Issue Published: 7 October 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...