tbuckley/cabot-search huggingface dataset:
Buffer Omission
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Measurement of Progress Against Cancer
Journal: JNCI Journal of the National Cancer Institute (1990)

Journal Article Measurement of Progress Against Cancer Get access Extramual Committee To Assess Measures of Progress Against Cancer Extramual Committee To Assess Measures of Progress Against Cancer Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 82, Issue 10, 16 May 1990, Pages 825–835, https://doi.org/10.1093/jnci/82.10.825 Published: 16 May 1990 Article history Received: 13 October 1989 Revision received: 25 January 1990 Accepted: 29 January 1990 Published: 16 May 1990
Injury Control
Authors: M. J. Allen
Journal: British Journal of Sports Medicine (1985)

This book provides a detailed study into the aetiology and prevention of injuries.It is an American publication so understand- ably some of the statistics presented are irrelevant to the British reader.The book is some 530 pages long and has no illust- rations, which makes for quite heavy reading.There is an extensive reference section at the end of the book covering some 84 pages.There is also a comprehensive index section.The first section of the book is concerned with a general overview of the concepts, methods and problems of injury control.The second section is devoted to specific injuries, including all types of vehicular accidents, rail, water, air and home acci- dents.There is also a section on thermal injuries.The third and final section discusses the high risk groups of the population in detail.I found the book to be well written and detailed in its approach to the subject but heavy going on occasions.It is not the book for the casual reader but would provide an excellent reference book to all those involved in the field of accident prevention.
Thrombosis in Primary Myelofibrosis: Incidence and Risk Factors.
Authors: Tiziano Barbui, Alessandra Carobbio, Francisco Cervantes, Alessandro M. Vannucchi, Paola Guglielmelli, Elisabetta Antonioli, Alberto Alvarez-Larràn, Alessandro Rambaldi, Guido Finazzi, Giovanni Barosi
Journal: Blood (2009)
In-depth molecular characterization of inherently resistant African HCV genotype 1, subtype 1l, in patients failing DAA-based therapy
Authors: Slim Fourati, Christophe Rodriguez, Alexandre Soulier, Lila Poiteau, Demontant Vanessa, Melissa N Debi, Stéphane Chevaliez, Hezode Christophe, Jean-Michel Pawlotsky
Journal: Journal of Hepatology (2020)
Influence of the MCAT on Premedical curricula
Authors: H. Markel
Journal: JAMA (1982)

<h3>In Reply.—</h3> Our article did try to assure premedical students that their chances for medical school admission are not necessarily damaged by pursuing a variety of undergraduate majors, as long as premedical science courses are successfully completed. Markel et al claim that the MCAT exerts such an influence on undergraduate course selection that premedical students will disregard the humanities in favor of high-level science courses that will improve MCAT performance. The behavior that the authors attribute to premedical students is consistent with the "premed syndrome," but to my knowledge there are no data on the MCAT's impact on course selection or choice of major. There are published data, however, that imply that enrolling in all the upper-level science courses one can handle, particularly biological sciences, does not appreciably improve MCAT performance. Presumably, biological science majors and premedical majors are those most likely to behave as Markel et al suggest. Hence,
Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions
Authors: Jie Du, Xiaonan Wang, Christiane Miereles, James L. Bailey, Richard Debigare, Bin Zheng, S. Russ Price, William E. Mitch
Journal: Journal of Clinical Investigation (2004)

With trauma, sepsis, cancer, or uremia, animals or patients experience accelerated degradation of muscle protein in the ATP-ubiquitin-proteasome (Ub-P'some) system. The initial step in myofibrillar proteolysis is unknown because this proteolytic system does not break down actomyosin complexes or myofibrils, even though it degrades monomeric actin or myosin. Since cytokines or insulin resistance are common in catabolic states and will activate caspases, we examined whether caspase-3 would break down actomyosin. We found that recombinant caspase-3 cleaves actomyosin, producing a characteristic, approximately 14-kDa actin fragment and other proteins that are degraded by the Ub-P'some. In fact, limited actomyosin cleavage by caspase-3 yields a 125% increase in protein degradation by the Ub-P'some system. Serum deprivation of L6 muscle cells stimulates actin cleavage and proteolysis; insulin blocks these responses by a mechanism requiring PI3K. Cleaved actin fragments are present in muscles of rats with muscle atrophy from diabetes or chronic uremia. Accumulation of actin fragments and the rate of proteolysis in muscle stimulated by diabetes are suppressed by a caspase-3 inhibitor. Thus, in catabolic conditions, an initial step resulting in loss of muscle protein is activation of caspase-3, yielding proteins that are degraded by the Ub-P'some system. Therapeutic strategies could be designed to prevent these events.
Elektrophysiologie der Pflanzen.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reduction of blood pressure with calcium supplementation in young adults
Authors: J. M. Belizan
Journal: JAMA (1983)

Epidemiologic and animal studies have suggested an inverse relationship between calcium intake and BP. Furthermore, calcium intake seems to be inversely correlated with the incidence of eclampsia in pregnancy. In a randomized clinical trial, young adults were allocated to a calcium-supplemented group receiving 1 g/day of elemental calcium (15 men and 15 women) or a placebo group (14 women and 13 men) for a period of 22 weeks. The calcium-supplemented group showed a significant decrease in diastolic BP; this effect was stabilized after nine weeks in women and six weeks in men. The reduction in diastolic BP was 5.6% and 9% from the initial values for women and men, respectively. This study supports epidemiologic and animal evidence of the effect of calcium intake on BP and suggests the need for more research exploring the mechanisms involved in the observed effect. (<i>JAMA</i>1983;249:1161-1165)
Arterial Surgery
Authors: Geza de Takats
Journal: JAMA (1970)

This lucid monograph on arterial surgery appears at a time when the rapid and sometimes unbridled growth of the subject has reached a stable plateau and when long-time follow-up and mature indications have crystallized and standardized surgical indications and techniques. Mr. Eastcott has profusely illustrated his book with photographs, effective line drawings, and last but not least, the marvelous angiograms of Dr. David Sutton. One regrets that he does not think much of the Callander amputation and that he does not mention the prognostic value of paravertebral blocks to anticipate gangrene after sympathectomy, although he does give an excellent analysis of the possible mechanisms involved. The chapters on carotid-vertebral insufficiency, on Raynaud's syndrome, and on renal and mesenteric ischemia are especially outstanding. The advantages of single authorship are also quite evident. Throughout the volume the close familiarity and deep involvement with the subject are obvious. One can unhesitatingly and enthusiastically
Die Tuberkulosebekämpfung Grundlagen und Wege zu einer einheitlichen und erfolgreichen Durchführung
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cancer, New York
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Portal Hypertension
Authors: Hugh H. Hussey
Journal: JAMA (1974)

The current (March 1974) issue of the<i>Archives of Surgery</i>contains a series of articles—a symposium—on the subject of portal hypertension, a condition of increasing frequency consequent to the growing incidence of alcoholic liver disease in the United States. The topics presented include the following: An assessment of the current status of hemodynamic measurements of the hepatic circulation in selection of patients for portal-systemic shunt. An analysis of the systemic cardiovascular abnormalities associated with portal hypertension and comments on the treatment of these disturbances. Histologic criteria, obtained from needle biopsy of the liver, for selecting patients for portacaval shunt. Early results of a prospective, randomized comparison of therapeutic portacaval shunt and medical therapy in selected good-risk patients who have bled from esophageal varices. Emergency medical therapy of bleeding esophageal varices by selective mesenteric arterial infusion of vasopressin. Early results of new techniques of portal
<i>Announcement:</i> National Birth Defects Prevention Month and Folic Acid Awareness Week — January 2017
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

The Zika virus disease outbreak has led to renewed focus on how some birth defects are caused by infection during pregnancy. "Prevent Infections for Baby's Protection" is the theme of January 2017's National Birth Defects Prevention Month. Birth defects are common, costly, and critical, and they affect one in 33 U.S. babies annually (1). Not all birth defects can be prevented, but women can increase their chances of having a healthy baby by reducing their risk for getting an infection during pregnancy.
DS05: Two‐thirds of patients may not require review after Mohs micrographic surgery
Authors: R Lapsley, S Fenwick, T Oliphant, D Jackson, E Edmiston, S Butt, M O'reilly, A Khalid, C Fleming
Journal: British Journal of Dermatology (2021)

has increased over the last 10 years, with more fellows completing UK-based fellowships.The average number of PAs allocated for MMS has also increased from 1Á84 to 2Á87.This study provides a valuable update to the 2011 national survey outcomes and serves as a benchmark of MMS practice for individual departments. DS05Two-thirds of patients may not require review after Mohs micrographic surgery
Motivation
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
From the Centers for Disease Control and Prevention. Drug-resistant Streptococcus pneumoniae--Kentucky and Tennessee, 1993
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Images and reflections
Authors: C. B. Clayman
Journal: JAMA (1981)

Elsewhere in this issue ofThe Journal(p 2728) is an excellent assessment of the role of ultrasonography, computed tomographic (CT) scanning, and radionuclide scintigraphy in the detection and drainage of abdominal abscesses. The accuracy of abscess detection and treatment by ultrasonography and CT scan await confirmation as use of these techniques is extended to smaller centers throughout the country. Ferrucci and vanSonnenberg report false-negative and false-positive results. Instances of misdiagnosis of lateral chest wall abscesses above or below the diaphragm, as well as misinterpretation of bowel air for abscess, have already been encountered. Emphasis on the need for careful clinical correlation of history and physical findings is reiterated. Ultrasophisticated diagnostic methods will not influence unduly a clinical decision among those whose experience and basic skills are well developed. Percutaneous drainage, the therapeutic extension of imaging diagnosis, whether by needle aspiration or by guided-wire— catheter drainage, has some attractive features.
Cost effectiveness analysis of different approaches of screening for familial hypercholesterolaemia
Journal: BMJ (2003)

depressant. 18Under normal circumstances, the interpenetration of industry and academe can be fruitful, as talent and ideas wash back and forth.Yet when drugs start earning the kind of money usually associated with the oil industry, there is potential for trouble. ConclusionsWe believe that the failure to advance the treatment of anxiety and depression is related to wrong classification.If you don't have natural disease categories, you can't develop drugs for them.If the Food and Drug Administration will accept only drugs that are effective for DSM diagnoses, and if the diagnoses are artefacts, the drugs are bound to be less valuable, even if in the short term they increase their market share.Companies must start developing drugs for mixed anxiety and depression and forget about dividing this giant illness segment into salami slices.Doctors could encourage this change by being more cynical about pitches from drug representatives claiming to have "the latest" in anxiolytic medication.Ask instead for the latest in nervousness. 19 Contributors and sources: ES has carried out research on historical aspects of psychiatry over many years, wherever possible studying documents that are key to the making of decisions by policy makers and psychiatric bodies.Most recently, he has worked in the archives of the US Food And Drug Administration and the American Psychiatric Association.PT has carried out clinical trials into the drug and psychological treatment of anxiety and depression since 1969 and has been involved in field trials for the 10th revision of the International Classification of Diseases (ICD-10).Competing interests: PT has received support from the Mental Health Foundation to evaluate the outcome of anxiety and depressive disorders.
Soluble fas in the serum of patients with non‐Hodgkin's lymphoma: Higher concentrations in angioimmunoblastic T‐cell lymphoma
Authors: Yuji Yufu, Ilseung Choi, Nobuhisa Hirase, Akihiro Tokoro, Yumi Noguchi, Tatsuro Goto, Naokuni Uike, Mitsuo Kozuru
Journal: American Journal of Hematology (1998)
Uremic Pruritus Treated With Ultraviolet Light
Authors: Bryan C. Shultz
Journal: JAMA (1980)

This study evaluated the treatment of uremic pruritus with ultraviolet B light in patients with chronic renal failure and severe pruritus not attributed to other skin or internal disease. Eight of ten patients responded with complete relief of itching. Photoinactivation of a yet unidentified substance could explain the success of this treatment. (<i>JAMA</i>243:1836-1837, 1980)
Incorrect Year.—
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Signaling commitment
Authors: Heather L. Van Epps
Journal: The Journal of Experimental Medicine (2005)

Brain-tethered T cellsOn page 1805, Kawakami et al. show that antigen-specific CD4 ϩ T cells that attack the brain become stationary within brain tissue, whereas nonspecific T cells cruise through without stopping.These intravital images-the first to capture T cells launching an autoimmune attack on the brain-suggest that antigenspecific T cells behave similarly in dense brain tissue as they do in lymph nodes.Activated CD4 ϩ T cells specific for the endogenous brain protein myelin basic protein (MBP) trigger fatal encephalomyelitis in a rat model of multiple sclerosis.These cells migrate into the central nervous system (CNS) where they become reactivated.Previous studies by this group showed that both antigen-specific and nonspecific T cells gain access to the CNS, but only specific cells become reactivated once there.Kawakami et al. now show that a subset of MBP-specific T cells-likely those that have encountered antigen-stopped moving inside the brain, appearing tethered to a fixed point.T cells specific for a control antigen kept moving, suggesting that the presence of antigen was required for T cells to stop moving and to trigger disease.The authors were surprised to find that T cells move as rapidly through the dense brain tissue as in the more aqueous environment of the lymph nodes.How they do this is not known but the authors suggest that the T cells may produce proteases that help clear a path through the compact tissue.