tbuckley/cabot-search huggingface dataset:
A Critical Review of Studies of the Association between Demands for Hospital Services and Air Pollution
Authors: Frederick W. Lipfert
Journal: Environmental Health Perspectives (1993)

Studies of the associations between air pollution and hospital admissions and emergency room use are reviewed, including studies of air pollution episodes, time-series analyses, and cross-sectional analyses.These studies encompass a variety of methods of analysis and levels of air quality.Findings from all three types of studies were generally consistent in that almost all of the studies reviewed found statistically significant associations between hospital use and air pollution; this unanimity may have resulted in part from publication bias.These associations were characterized by elasticities of the order of 0.20; i.e., a 100% change in air pollution was associated with a change in hospital use of about 20%, for specific diagnoses.Respiratory diagnoses were emphasized by most studies; cardiac diagnoses were included in five ofthem.The air pollutants most often associated with changes in hospital use were particulate matter, sulfur oxides, and oxidants.Apart from the major air pollution episodes, there was no obvious link between air pollution level and the significance or magnitudes of the associations.Long-term indicators of hospitalization appeared to also be influenced by medical care supply factors, including the numbers of beds and physicians per capita.These nonpathological causal factors could also have influenced the findings of the time-series studies by introduc- ing extraneous factors in the patterns of admissions.Although consistent associations have been shown between hospital use and air pollution, further research is required to distinguish among potentially responsible pollutants and to deduce specific dose-response relationships of general utility.
A pilot study of recombinant interleukin-2 for treatment of chronic hepatitis C.
Authors: M Pardo
Journal: Hepatology (1997)

The optimal and safer interleukin-2 (IL-2) dose for treatment of chronic hepatitis C virus (HCV) infection has been studied in 33 HCV-RNA positive patients with chronic hepatitis C. Patients were randomly allocated to receive 5 days per week during 12 weeks IL-2 doses of: 0.9 MIU (n = 10), 1.8 MIU (n = 10), or 3.6 MIU (n = 13). After 12 weeks, responder patients stopped treatment, whereas nonresponders received 12 additional weeks of IL-2 at the next higher dose: 1.8, 3.6, or 5.4 MIU. As a whole, after the first 12 weeks of IL-2 alanine aminotransferase (ALT) levels significantly decreased (P < .001) with respect to the baseline values (140 +/- 63 vs. 70 +/- 30 IU/L). At the end of treatment (24 weeks), the mean ALT level (80 +/- 50 IU/L) continued significantly lower (P < .001) than the baseline one, and 24% of patients normalized ALT levels; according to dosage, ALT normalization was: 0% for 0.9 MIU, 25% for 1.8 MIU, 5% for 3.6 MIU, and 18% for 5.4 MIU. HCV-RNA levels decreased during treatment, but in none of the patients became undetectable. All patients had a local reaction at the injection site with induration, erythema, and swelling, which was dose- related. The dose of 5.4 MIU was poorly tolerated and was reduced to 3.6 MIU in 4 of 11 patients. No changes in hematological parameters were observed. At the end of follow-up (6 months) four of eight responder patients continued with normal ALT. In conclusion, IL-2 treatment for chronic hepatitis C induced a biochemical response in 8 of 33 (24%) patients at the end of therapy while at the end of follow-up, 4 of 33 (8%) patients remained with normal ALT. The dose of 1.8 MIU is well tolerated and seems to be the most efficacious. (Hepatology 1997 Nov;26(5):1318-21)
INHERITANCE OF CIRCUMCISION EFFECTS.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE RELATION OF CARDIAC IRREGULARITIES TO TREATMENT
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Skating or Surgery, Goal Is Perfection
Journal: JAMA (1976)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The American and His Food: A History of Food Habits in the United States
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Symposium on Cancer of the Skin and Mouth
Journal: JNCI Journal of the National Cancer Institute (1974)

Journal Article Symposium on Cancer of the Skin and Mouth Get access JNCI: Journal of the National Cancer Institute, Volume 52, Issue 5, May 1974, Page 1679, https://doi.org/10.1093/jnci/52.5.1679 Published: 01 May 1974
The Mind: First Steps.
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Zellaufbau der Grosshirnrinde des Menschen.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
成人和儿童银屑病诊断标准系统论述:主要目的是为制定或验证诊断标准的研究而得出的证据
Authors: E. Burden-Teh, R.C. Phillips, K.S. Thomas, S. Ratib, D. Grindlay, R. Murphy
Journal: British Journal of Dermatology (2018)

银屑病是一种皮肤和关节疾病。它会导致身体任何部位的皮肤发生红肿和剥落,并且使关节肿胀。在全球范围内,100名成人中有8名银屑病患者,100名儿童中有2名银屑病患者。该评述的研究人员居住在英国诺丁汉和谢菲尔德。评述目的在于找到制定银屑病诊断标准的所有研究,并收集有关标准对诊断银屑病的有效性的结果。诊断标准一词是指在同时存在的情况下可确诊银屑病的一系列项目。为了完成这项评述,研究人员搜索了在线研究数据库、总结了相关发现并检验了研究质量。发现有二十三项研究制定了诊断标准。这些标准包括基因和实验室标准、使用皮肤成像技术的标准、基于皮肤活检发现的微观变化的标准、使用计算机算法的标准、基于调查问卷的标准以及中医使用的标准。这23项研究中的标准大部分能够有效诊断银屑病,但通常需要以检验作为依据,还需要配合医疗咨询。基于检验的标准通常需要特定设备或皮肤/血液采样。23项诊断标准均不涉及在体检中观察皮肤,这最能够反映当前的医疗实践且可用于其他皮肤病。此类标准将对医疗专业人士和研究人员有帮助。
Proteostasis improvement in cystic cholangiocytes alleviates endoplasmic reticulum stress and halts polycystic liver disease
Authors: Alvaro Santos-Laso, Laura Izquierdo-Sánchez, Pedro Miguel Rodrigues, Bing Q Huang, Mikel Azkargorta, Ainhoa Lapitz, Patricia Munoz-Garrido, Ander Arbelaiz, Francisco J. Caballero, Maite G Fernandez-Barrena, Raul Jimenez-Aguero, Josepmaria Argemi, Tomas Aragon, Felix Elortza, Marco Marzioni, Joost Ph Drenth, Nicholas Larusso, Luis Bujanda, Mariá Jesús Perugorria, Jesus M. Banales
Journal: Journal of Hepatology (2020)
Impact of Additional Cytogenetic Alterations At Diagnosis on Prognosis of CML: Long-Term Observation From 1151 Patients of the Randomized CML Study IV
Authors: Alice Fabarius, Armin Leitner, Andreas Hochhaus, Martin C Müller, Claudia Haferlach, Gudrun Göhring, Brigitte Schlegelberger, Martine Jotterand, Andreas Reiter, Susanne Jung-Munkwitz, Ulrike Proetel, Juliana Schwaab, Wolf-Karsten Hofmann, Joerg E. A. Schubert, Hermann Einsele, Anthony D. Ho, Christiane Falge, Lothar Kanz, Andreas Neubauer, Michael Kneba, Frank Stegelmann, Michael Pfreundschuh, Cornelius F. Waller, Wolfgang Hiddemann, Gabriela M. Baerlocher, Michael Lauseker, Markus Pfirrmann, Susanne Saussele, Rüdiger Hehlmann, Joerg Hasford
Journal: Blood (2011)
Endocrine Physiology
Authors: Maria I. New
Journal: JAMA (1986)

Review of Constance Martin's book finds it to be an excellent, comprehensive work on steroid and peptide hormones. The book is organized in an interesting way: systems are discussed according to function. Most endocrine systems are well described. This includes a clear and complete discussion of the current knowledge of neuroendocrinology and the role of the autonomic nervous system in hormonal regulation. New roles for peptides in mediating hormone action and current information about newly discovered peptides and nonsteroidal hormones important to endocrine systems are presented. One of the outstanding features of this book is that it provides the endocrinologist with an excellent basic test on peptides and steroid biochemistry and cell physiology. These chapters are well written and replete with easily comprehended diagrams and illustrations. Another great strength is the comparative approach to an in-depth description of endocrine systems in mammals other than man. Although the book only touches
Acute hepatic and renal toxicity from low doses of acetaminophen in the absence of alcohol abuse or malnutrition: Evidence for increased susceptibility to drug toxicity due to cardiopulmonary and renal insufficiency
Authors: H Bonkovsky
Journal: Hepatology (1994)

A 67-yr-old man with chronic cardiopulmonary disease exhibited severe hepatic and moderately severe renal injury after short-term ingestion of therapeutic doses of acetaminophen (1 to 3 gm/day for 3 days). Drug metabolism and other studies, performed 5 mo after recovery from the acute insult, indicated that the patient had decreased rates of hepatic metabolism of acetaminophen to its primary, nontoxic metabolites and decreased kidney function that was compromised further by acetaminophen ingestion. He also had abnormally low concentrations of hepatic and plasma reduced glutathione. Alcohol abuse and malnutrition could not be implicated in the pathogenesis of injury; rather it appeared that advancing age with chronic renal, cardiac and pulmonary insufficiency contributed to acetaminophen toxicity in this patient. (HEPATOLOGY 1994;19:1141–1148.)
Cellular Responses to DNA Damage
Authors: Graham C. Walker, Lorraine Marsh, Lori Dodson
Journal: Environmental Health Perspectives (1985)

For many years, the study of the regulation of the SOS network was complicated by both the complexities of the responses and the interrelationships of the key regulatory elements. However, recently the application of powerful genetic and molecular biological techniques has allowed us to gain a detailed picture of the regulation of this complex network. The network is now known to consist of more than 17 genes, each of which is repressed by the LexA protein. Induction of the genes in the SOS network occurs when the RecA protein becomes activated in response to a signal generated by DNA damage. Two of the genes in this network, umuD and umuC, are absolutely required for mutagenesis by UV and various carcinogens. The umuD and umuC genes have molecular weights of 16,000 and 45,000 daltons, respectively, and are organized in an operon repressed by LexA. The mutagenesis-enhancing plasmid pKM101 carries two genes mucA and mucB, which are analogs of the umuD and umuC genes, respectively.
Comparison of adenoma detection and miss rates between a novel balloon colonoscope and standard colonoscopy: a randomized tandem study
Authors: Zamir Halpern, Seth Gross, Ian Gralnek, Beni Shpak, Mark Pochapin, Arthur Hoffman, Meir Mizrahi, Yosef Rochberger, Menachem Moshkowitz, Erwin Santo, Alaa Melhem, Roman Grinshpon, Jorge Pfefer, Ralf Kiesslich
Journal: Endoscopy (2015)

<b>Background and study aims:</b> Although colonoscopy is the "gold standard" for colorectal cancer screening, a significant number of adenomas are still missed during standard colonoscopy, often because they are hidden behind colonic folds and flexures. The aim of this study was to assess the ability of a novel balloon colonoscope (G-EYE endoscope; Smart Medical Systems, Ra'anana, Israel) to increase adenoma detection and reduce the miss rate compared with standard colonoscopy. <b>Patients and methods: </b>This was a multicenter, randomized, prospective, controlled study in patients (age ≥ 40 years) undergoing colonoscopy for screening or diagnostic work-up (including surveillance). Patients underwent same-day, back-to-back tandem colonoscopy. Patients in Group A underwent standard colonoscopy followed by balloon colonoscopy, and patients in Group B underwent balloon colonoscopy followed by the standard technique. The adenoma detection and miss rates were compared between the two colonoscopy procedures. <b>Results:</b> A total of 126 patients were enrolled and randomized into Group A (n = 60) or Group B (n = 66). The adenoma miss rate of balloon colonoscopy was significantly lower than that of standard colonoscopy (7.5 % vs. 44.7 %; <i>P</i> = 0.0002). The detection of additional adenomas by balloon colonoscopy was significant (81.0 %; P = 0.0002), in particular, the relative amount of adenomas detected in the ascending colon by balloon colonoscopy was 41 % versus 14 % for standard colonoscopy. <b>Conclusions:</b> A novel balloon colonoscopy technique detected significantly more adenomas than standard colonoscopy, and missed fewer adenomas. Balloon colonoscopy has the potential to increase the effectiveness of colorectal cancer screening and surveillance colonoscopy.
Chronic Bronchitis
Authors: Sanford Chodosh, Maurice S. Segal
Journal: New England Journal of Medicine (1964)

THE most common cause of inadequate therapy of chronic bronchitis is failure of recognition. There has been a reluctance to consider that the symptoms of chronic cough and phlegm production may add up to a disease worthy of concern. Persons manifesting these symptoms may be diagnosed as being normal subjects, or as having "smoker's cough," mild bronchitis, chronic bronchitis or bronchiectasis. This variability of interpretation by different physicians led investigators in this field to try to standardize the nosology so that chronic bronchitis — and other chronic bronchopulmonary diseases — would be properly diagnosed. However, even when the proper diagnosis . . .
Planning and preparing scientific exhibits
Authors: A. H. Bulbulian
Journal: JAMA (1965)

This exhibit presents certain basic principles in the preparation of a good scientific exhibit and demonstrates the various media and techniques that may be used to produce an exhibit that has maximal teaching value. The author has chosen a number of previously prepared exhibits, representing various categories of subjects, and has made an analysis of the way in which each subject was handled so as to achieve the most effective form of presentation. <h3>In Planning A Scientific Exhibit Keep In Mind That</h3> Your Audience... ...is not captive, as in a lecture, but is free to move on to another exhibit that is simultaneously competing for attention. Have your exhibit contain an arresting feature directly related to your subject matter and convince your audience initially and forcefully that you have a worthwhile message. ... will first see the total exhibit as a unit and is prone to be affected by its overall
Liver Disease in Patients Receiving Home Intravenous Feeding
Journal: Annals of Internal Medicine (2000)

Summaries for Patients4 April 2000Liver Disease in Patients Receiving Home Intravenous FeedingSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-7-200004040-00037 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Some people with diseases of the digestive tract (particularly those with diseases that require surgery to remove a large part of the intestine) require permanent feeding through a small tube inserted into a vein (intravenous feeding). Liver damage can be a side effect of intravenous feeding. That complication is not uncommon, but its exact frequency is not known. The liver damage may involve only a mild backup of bile (known as chronic cholestasis), which does not keep the liver from functioning. In other instances, the damage is more ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Prevalence of Liver Disease and Contributing Factors in Patients Receiving Home Parenteral Nutrition for Permanent Intestinal Failure.”. It is in the 4 April 2000 issue of Annals of Internal Medicine (volume 132, pages 525-532). The authors are M. Cavicchi, P. Beau, P. Crenn, C. Degott, and B. Messing.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPrevalence of Liver Disease and Contributing Factors in Patients Receiving Home Parenteral Nutrition for Permanent Intestinal Failure Maryan Cavicchi , Philippe Beau , Pascal Crenn , Claude Degott , and Bernard Messing Metrics 4 April 2000Volume 132, Issue 7Page: 525KeywordsBiopsyFatsHematologic testsLiverLiver diseasesLiver transplantationNutritionSurgeryUltrasound imagingVeins ePublished: 15 August 2000 Issue Published: 4 April 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.Loading ...
Abstracts Pt.36
Authors: Naga Grandhe, Anil Bhansali, Sunil Dogra, Carlos Serra-Guille ´n, Alberto Alfaro-Rubio, Manuel Velasco, Enrique Gimeno, Agustin Martin-Clavijo, Binh Ngo, Miroslaw Smogorzewski, David Woodley, Marc Rendell, Aerlyn Dawn, Amy Devore, Gil Yosipovitch, Gokhan Okan, Umit Ince
Journal: Journal of the American Academy of Dermatology (2006)