tbuckley/cabot-search huggingface dataset:
ALL IS NOT HONEY
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
GYNÆCOLOGICAL SOCIETY OF BOSTON.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Communications satellites in health education and health care provision. The WAMI experience
Authors: M. R. Schwarz
Journal: JAMA (1983)

Since 1971, the University of Washington School of Medicine, Seattle, has operated a four-state, medical education program covering Washington, Alaska, Montana, and Idaho. This WAMI Program involves four universities without medical schools and 15 communities. To maintain this program, communication between the sites is imperative and mandates travel. The experiments described in this article were undertaken to determine whether full-duplex audio and color-video interactions via communications satellites could replace the travel requirements of the WAMI Program. Experiments involving the administration of the program, the presentation of the undergraduate medical education curriculum, the provision of health services, and the formation of public policies were conducted. The results suggest that satellite communication has broad applicability in medical education and health care provision. (<i>JAMA</i>1983;250:636-639)
Issue Information
Authors: Daniel Solomon, Richard Bucala, New Haven, Mariana Kaplan, Peter Nigrovic, Boston Co, Karen Costenbader, David Felson, Richard Loeser, Chapel Hill, Paul Sufka, St Paul, Shervin Assassi, Adam Berlinberg, Deborah Feldman, Meenakshi Jolly, Donnamarie Krause, Las Vegas, Uyen-Sa Nguyen, Michelle Ormseth, Nashville Scofield, Oklahoma City, Jane Diamond, Atlanta Lesley, W Allen, Atlanta Ilani, S Lorber, Atlanta Barraza, Atlanta Hamilton, Emily Wehby, Atlanta Stefanie, L Mckain, Atlanta Swett, Will Galanis, Marta Alarcón-Riquelme, Heather Allore, Neal Basu, Edward Behrens, Bryce Binstadt, John Carrino, New York, Lisa Christopher-Stine, Baltimore Cope, Nicola Dalbeth, Brian Feldman, Richard Furie, Great Neck, J Kahlenberg, Ann Arbor, Benjamin Leder, Yvonne Lee, Katherine Liao, Bing Lu, Anne-Marie Malfait, Stephen Messier, Winston-Salem Janet, E Pope, Christopher Ritchlin, Rochester Robinson, Georg Schett, Sakae Tanaka, Maria Trojanowska, Betty Tsao, Fredrick Wigley, Abhishek Abhishek, Nottingham Aghayev, Tom Appleton, Joshua Baker, Bonnie Bermas, Jamie Collins, Christopher Denton, Anisha Dua, John Fitzgerald, Angeles Haroon, Monique Hinchcliff, Hui-Chen Hsu, Vasileios Kyttaris, Carl Langefeld, Winston-Salem Lories, Suresh Mahalingam, Dennis Mcgonagle, Aridaman Pandit, Kevin Winthrop, Julie Zikherman, San Francisco, American College, O Rheumatology, David Karp, Kenneth Saag, Douglas White, La Crosse, Deborah Desir, Steven Echard, Joht Chandan, Tefra Zemedikun, Rasiah Thayakaran, Nathan Byne, Samir Dhalla, Dionisio Acosta-Mena, Krishna Gokhale, Tom Thomas, Christopher Sainsbury, Anuradhaa Subramanian, Jennifer Cooper, Astha Anand, Kelvin Okoth, Jingya Wang, Nicola Adderley, Thomas Taverner, Alastair Denniston, Janet Lord, G Thomas, Christopher Buckley, Karim Raza
Journal: Arthritis & Rheumatology (2021)

in At-Risk First-Degree Relatives Cover image: The fi gure on the cover (from Yuba et al, pages 769-778) shows immunofl uorescence staining of popliteal lymph node from an arthritic BALB/c mouse after intravenous injection of DyLight 594-labeled serum albumin-fused interleukin-10 (SA-IL-10).Specimens were stained for anti-CD3 (green) and DAPI (blue).Location of SA-IL-10 appears in red.
Hepatic interferon-α gene transcripts and products in liver specimens from acute and chronic hepatitis B virus infection
Authors: K Nouri-Aria
Journal: Hepatology (1991)

In this study we have examined the localization of interferon-α in liver tissue from acute and chronic hepatitis B virus carriers to establish whether the defect in interferon-α production reported in chronic hepatitis B virus infection is at a pretranscriptional or posttranscriptional level using in situ hybridization and immunohistochemical techniques. Interferon-α messenger RNA transcripts and the immunoreactive protein were abundant in liver tissue and in particular in hepatocytes from patients with acute hepatitis B virus infection who ubsequently recovered. In contrast interferon-α polypeptide was present in a significantly lower number of sinusoidal cells, mononuclear cells and hepatocytes in chronic hepatitis B virus carriers. Although a high proportion of patients with chronic hepatitis B virus infection had cells that expressed interferon-α messenger RNA transcripts, the number of such cells was significantly less than in acute hepatitis B virus infection, indicating that the defect in the hepatic interferon-α synthesis is at the level of gene activation. Furthermore, using double immunohistochemical staining, the number of hepatocytes containing HBcAg correlated inversely with the proportion of neighboring sinusoidal cells expressing interferon-α These data support previous observations that interferon-α production is reduced in chronic hepatitis B virus infection and are consistent with the view that this cytokine is important in the clearance of the virus. (HEPATOLOGY 1991;13:1029–1034.)
Reconstructive coronary artery surgery. Venous autograft technique
Authors: W. C. Sheldon
Journal: JAMA (1970)

From May 1967 through May 1969, a total of 303 patients underwent venous autograft reconstructions for occlusive coronary artery disease, with an overall mortality of 5.6%. With subsequent experience the hospital mortality has been reduced to less than 5%. The first 100 patients have been followed-up for more than one year. Eighty-six percent of the survivors have had postoperative angiographic study, and in 86% of these the graft was demonstrated to be patent. Eighty percent had no significant residual obstruction in the artery operated upon and there was good correlation between the angiographic result and symptomatic improvement. The venous autograft technique offers immediate restoration of more effective myocardial perfusion, with attendant protection against myocardial infarction and improvement in symptoms of myocardial ischemia.
Thyroid Cancer Brain Metastasis
Authors: Joseph R. Osborne, Jessica D. Kondraciuk, Samuel L. Rice, Xiaosun Zhou, Andrea Knezevic, Daniel E. Spratt, Mona Sabra, Steven M. Larson, Ravinder K. Grewal
Journal: Clinical Nuclear Medicine (2019)

Brain metastases (BMs) in patients with differentiated thyroid cancer (DTC) are rare but associated with poor prognosis. We examined risk factors for overall survival (OS) in this population and explored the pattern of genomic alterations.Single-institution, retrospective review of all patients with DTC from January 2000 to November 2016 identified 79 patients for analysis. Multiple prognostic factors, including age, gender, distal metastasis (DM), diagnosis time, DM sites, BM diagnosis time, BM number and size, genomic sequencing data, craniectomy, external beam radiation therapy, and kinase inhibitor therapies, were evaluated. Univariate and multivariate analyses were performed.Median survival after BM was 18 months. One- and 3-year survival rates were 63% and 33%, respectively. Univariate analysis identified 4 covariates correlated with prolonged survival: time between DTC diagnosis and BM for less than 3 years (P = 0.01), time from initial DM diagnosis to BM for 22 months or less (P = 0.03), 3 BM sites or fewer (P = 0.002), and craniectomy (P = 0.05). Multivariate model revealed 3 variables associated with OS: DTC diagnosis to BM time of less than 3 years (P = 0.04), craniectomy (P = 0.06), and patients with fewer than 3 BM sites (P = 0.06). The majority of patients with BM had a telomerase reverse transcriptase promoter mutation, However, mutational status was not an independent predictor of survival.For BM from DTC, time interval between DTC diagnosis and BM, number of BM sites, and craniectomy were independently associated with OS. Further studies are needed to define the role of genomic mutations in advanced cancer.
Yerkes Primate Studies Yielding Clinical Fruit, Results Useful in Ophthalmology, Behavioral Science
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TEMPORAL TRENDS IN ISCHEMIC HEART DISEASE MORTALITY IN 21 WORLD REGIONS, 1980-2010: THE GLOBAL BURDEN OF DISEASE 2010 STUDY
Authors: Andrew Edward Moran, Mohammad H. Forouzanfar, Abraham D. Flaxman, Gregory Roth, George Mensah, Majid Ezzati, Mohsen Naghavi, Christopher JL Murray
Journal: Journal of the American College of Cardiology (2013)
Comparative Female Reproductive Tract Development and Morphology
Authors: Richard M. Hoar
Journal: Environmental Health Perspectives (1978)

A brief description of the basic pattern of mammalian organogenesis of the female reproductive tract is presented based on events as they occur in human beings. The emphasis is not on the details of this development, but rather its organization and timing. Tables of comparative development provide a comparison of similar events between man, rat, mouse, and chick.
Tricuspid Valve Replacement Examined
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reply
Authors: J Christiansen
Journal: Gut (1992)

<h3>Background</h3> Little is known about COVID-19 information-seeking experiences for culturally and linguistically diverse groups in Australia. <h3>Methods</h3> Participants were recruited using a cross-sectional survey from March 21 to July 9, 2021, translated into 11 languages, and with supporting bilingual staff. Linear regression models identified factors associated with difficulty finding easy-to-understand COVID-19 information. <h3>Results</h3> Across 708 participants (88% born overseas, 31% poor English proficiency), difficulty finding easy-to-understand COVID-19 information was rated 4.13 for English materials (95%CI: 3.85 to 4.41) and 4.36 for translated materials (95%CI: 4.07 to 4.66) (1 easy to 10 hard). Participants who were older (p&lt;0.001), had inadequate health literacy (Mean Difference (MD)=-1.43, 95%CI -2.03 to - 0.82, p&lt;0.001), or poor English proficiency (MD=-1.9, 95%CI-2.51 to -1.29, p&lt;0.001) found it harder to find easy-to-understand English-language COVID-19 information. Those who had greater difficulty finding easy-to-understand translated COVID-19 information were younger (p=0.004), had poor English proficiency (MD=-1.61, 95%CI -2.29 to -0.9, p&lt;0.001), university education (MD=0.77, 95%CI 0.00 to 1.53, p=0.05), and had spent longer living in Australia (p=0.001). They were more likely to rely on friends and family for COVID-19 information (p=0.02). There was significant variation in information-seeking experiences across language groups (p’s&lt;0.001). <h3>Conclusions</h3> Easy-to-understand and accessible COVID-19 information is needed to meet the needs of people in culturally and linguistically diverse communities. This approach should involve working alongside these communities to tailor messages and leverage existing communication channels.
Book Review Neurology . By S. A. Kinnier Wilson, M.D., D.Sc. (Edin.), F.R.C.P. Edited by A. Ninian Bruce, F.R.C.P. (Edin.), D.Sc. (Edin.), M.D., F.R.S. (Edin.). Two volumes. 8°, cloth. Vol. 1, 751 pp., with 114 illustrations and 117 plates. Vol. 2, 1085 pp., with 217 illustrations and 73 plates. Baltimore: The Williams and Wilkins Company, 1940. $21.00 for the set.
Journal: New England Journal of Medicine (1943)
PERITONEAL SUPPORTS—(LIGAMENTUM PERITONEI.)
Authors: BYRON ROBINSON
Journal: JAMA (1895)

The hepatic artery produces only a slight elevation of peritoneum until it reaches the hepato-duodenal ligament, whence it aids in giving distinct outline to the border of Winslow's foramen on the right. By opening an adult cadaver, well prepared for inspection, and then carefully incising the gastro-colic omentum, one can see with perfection the shape and form of the left opening of Winslow into the lesser omental bag. To obtain the best view of Winslow's foramen, however, the ribs on both sides should be removed and the stomach lifted well up. Winslow's foramen will then be seen to have a distinct oval form as seen from inside the lesser bag, whose circumference is nearly all produced by peritoneal folds projected by the gastric and hepatic arteries. The splenic artery, I must say, contrary to some anatomists, does not run into the gastro-splenic ligament until it nears its termination. Beginning at
Abstract 3799: Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer
Authors: Haeseung Lee, Ok-Seon Kwon, Wankyu Kim, Hyuk-Jin Cha
Journal: Cancer Research (2019)

Abstract Even when targets responsible for chemoresistance are identified, drug development is often hampered due to the poor druggability of these proteins. We systematically analyzed therapy-resistance with a large-scale cancer cell transcriptome and drug-response datasets and predicted the candidate drugs based on the gene expression profile. Our results implicated the epithelial-mesenchymal transition as a common mechanism underlying resistance to chemotherapeutic drugs. Notably, we identified ITGB3, whose expression was abundant in both drug resistance and mesenchymal status, as a promising target to overcome chemoresistance. We also confirmed that depletion of ITGB3 sensitized cancer cells to conventional chemotherapeutic drugs by modulating the NF-κB signaling pathway. Considering the poor druggability of ITGB3 and the lack of feasible drugs to directly inhibit this protein, we took an in silico screening for drugs mimicking the transcriptome-level changes caused by knockdown of ITGB3. This approach successfully identified atorvastatin as a novel candidate for drug repurposing, paving an alternative path to drug screening that is applicable to undruggable targets. Citation Format: Haeseung Lee, Ok-Seon Kwon, Wankyu Kim, Hyuk-Jin Cha. Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 3799.
General Principles in Toxicology and Toxicologic Pathology—Course
Journal: JNCI Journal of the National Cancer Institute (1985)

General Principles in Toxicology and Toxicologic Pathology—Course Get access JNCI: Journal of the National Cancer Institute, Volume 74, Issue 5, May 1985, Page 1153, https://doi.org/10.1093/jnci/74.5.1153-b Published: 01 May 1985
OCULAR SYMPTOMS OF THE LITHEMIC STATE.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Haemophilus influenzae type b disease. Incidence in a day-care center
Authors: C. M. Ginsburg
Journal: JAMA (1977)

<i>Haemophilus influenzae</i>type b (HIB) disease was observed during a 14-month period in seven of 48 infants attending a day-care center. Surveillance studies showed that 28 (58%) infants had positive nasopharyngeal cultures for HIB; four infants were colonized with HIB for nine to 12 months. Ampicillin trihydrate prophylaxis failed to reduce the HIB carrier rate.<i>Haemophilus influenzae</i>type b polysaccharide vaccine was administered to 34 of the children. Sera obtained prior to immunization showed detectable antibody in all infants. Only nine (26%) infants had twofold or greater rises in serum HIB antibody titers after vaccination. Antibody response was independent of age, preimmunization antibody concentration, and HIB carrier status. In one infant, HIB meningitis developed four months after she received polysaccharide vaccine. This outbreak emphasizes that HIB is highly contagious in closed populations of young, susceptible infants. (<i>JAMA</i>238:604-607, 1977)
HEMODYNAMIC BALANCE AND THE KIDNEY
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Viral hepatitis: an occupational hazard to surgeons
Authors: J. L. Rosenberg
Journal: JAMA (1973)

An epidemic of serum hepatitis (hepatitis-associated antigen [HAA]-positive) among surgical house staff occurred at Albert Merritt Billings Hospital in the winter of 1971. Four surgeons, who had operated on a patient in whom HAA-positive serum hepatitis subsequently developed, were affected. Arthralgia or arthritis and rash were prominent clinical features of this outbreak. Reduced synovial fluid complement level and a synovial fluid that was HAA-positive were found in one of the surgeons. A detailed evaluation of the 75 medical and allied medical personnel who cared for this patient before, during, and after surgery uncovered no additional cases of hepatitis. We believe, therefore, that the serum hepatitis virus was transmitted to the surgeons while they were operating, most likely through tissue penetration by contaminated surgical instruments or materials.