tbuckley/cabot-search huggingface dataset:
Familial Risk of Lung Carcinoma in the Icelandic Population—Correction
Authors: Howard Ritter, Harvey Edmonds
Journal: JAMA (2005)

ming sperm." 1 This description is supremely felicitous, as the Veil Nebula is, in fact, the tattered remnants of a supernova-an exploding star.But there is a far deeper connection.The universe started with little other than hydrogen and helium, and none of the heavy elements of our familiar world and ourselves.The heavier elements up through iron are produced inside massive stars much heavier than the sun, by thermonuclear fusion during the stable portions of their lives.When such stars reach the end of their useable nuclear fuel, they become unable to sustain their own weight, collapse, and rebound in a titanic explosion.This blast, occupying the last few seconds of the star's existence, synthesizes the elements heavier than iron and blows the entire star, aside from the core, into free space, where the heavy elements enrich the hydrogen and helium of the pristine interstellar medium.The next generation of stars and planetary systems born of the enriched gas thereby possesses the heavy elements required for the formation of solid planets and for life.Thus are we all, as astrophysicists and songwriters are wont to say, stardust.In this sense, the supernova actually is how "life begins."The portion shown in the (much overexposed) photograph in the painting is called the Western Veil and is part of a larger complex called the Cygnus Loop, which is about 15000 years old, 2500 light years away, 4 times the apparent diameter of the full moon, but very faint.Examined at leisure through a large telescope, under dark and transparent skies, the Veil Nebula is a complex, subtle, and sublime sight.Excellent photographs of the Veil Nebula can be found at the Web site of the National Optical Astronomy Observatories.
THE SCHOOLCHILD BEFORE AND AFTER TONSIL AND ADENOID REMOVAL
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reference Omitted
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
HYDROPHOBIA.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment of primary and secondary syphilis: defining failure at three- and six-month follow-up
Authors: M. E. Guinan
Journal: JAMA (1987)

In 1985, approximately 28 000 cases of primary and secondary syphilis were reported in the United States (Centers for Disease Control, unpublished data). A large proportion of these patients were treated with the recommended therapy, 2.4 million units of penicillin G benzathine given intramuscularly in one dose.<sup>1</sup>The proportion of patients who were cured with this regimen, however, is not known. No simple test is available that determines cure of syphilis within days (or even weeks) of treatment. To assess treatment, the patient is asked to return for a repeated serological test and clinical evaluation at varying intervals after treatment, usually 3-, 6-, and 12-month visits or until the patient is seronegative. When the serological test results revert to negative, the patient is considered cured. However, when they remain positive, a clinical dilemma arises. Criteria for determining treatment failures (or possible failures) during follow-up visits include the following: (1)
Periodic ataxia
Authors: E. DeCastro
Journal: JAMA (1967)

IN 1946 Parker<sup>1</sup>described a bizarre but clearcut symptom complex consisting of acute transient general cerebellar dyssynergia, affecting all muscles of the body, including those of articulation. These attacks last no longer than a few seconds to a few minutes, and disappear just as suddenly as they come on. The patient then reverts to his former condition, normal or otherwise. He described 11 cases, six associated with some phase of multiple sclerosis. The condition in another four was due to familial cerebellar ataxia, but their periodic attacks were more violent and bitterly complained of. One unusual case was an instance of degenerative spinocerebellar ataxia. This syndrome was termed "periodic ataxia." In 1959, Andermann et al<sup>2</sup>studied two patients with multiple sclerosis who had paroxysmal attacks of dysarthria and ataxia. The cardinal features were the sudden paroxysmal occurrence and brief duration of the attacks.<sup>3</sup>The cerebellum or its connections
Diagnostic performance of three non-invasive fibrosis scores (Hepamet, FIB-4, NAFLD score) on NAFLD in a mixed Latin American population
Authors: Rommel Zambrano-Huailla, Laura Guedes, Arthur A. Arrais de Souza, Jose Tadeu Stefano, Sebastián Marciano, Erika Yvamoto, Matheus Truccolo Michalczuk, Denise Siqueira Vanni, Hernan Rodriguez, Flair Jose Carrilho, Mario Reis Álvares-da-Silva, Marco Arrese, Adrian Gadano, Adelina Lozano Miranda, Claudia Oliveira
Journal: Journal of Hepatology (2020)
Patupilone combined with carboplatin in patients (pts) with advanced solid tumors: preliminary safety and activity results
Authors: P. M. Fracasso, A. Ravaud, M. Q. Baggstrom, P. M. LoRusso, D. V. Jones, C. Sguotti, P. Urban, B. Gao, J. Medioni
Journal: Journal of Clinical Oncology (2008)

13544 Background: Patupilone is a novel microtubule targeting agent with demonstrated clinical activity in taxane-sensitive/resistant tumors and synergistic tumor activity when combined with carboplatin in preclinical models. This Phase I study aimed to determine the maximum-tolerated dose (MTD) and dose-limiting toxicity (DLT) of patupilone combined with carboplatin. Secondary endpoints included safety, pharmacokinetics (PK) and assessment of anti-tumor activity. Methods: Pts with solid advanced tumors who progressed after standard therapies received escalating doses of patupilone followed by carboplatin (AUC=6) once every 3 wks. A Bayesian logistic model with overdose control and a starting dose of 4.8 mg/m2 determined the MTD of patupilone. Results: To date, 18 pts have been enrolled into the study receiving a total of 57 cycles. Median age: 60 years (range: 37–79). Tumor types included prostate (5), colon (3), renal (1), bladder (1), endometrial (1), NSCLC (1), breast (1), thymus (1), head and neck (1), melanoma (1) and unknown primary (2). Six pts are ongoing and 12 discontinued: 1 due to toxicity (G3: diarrhea). To date the MTD has not been reached. Dose escalation levels of patupilone 4.8 mg/m2 (6 pts), 6.4 mg/m2 (3 pts), 7.0 mg/m2 (6 pts) and 7.5 mg/m2 each followed by carboplatin (AUC=6) have been administered. One DLT of G2 neutropenia lasting >14 days was reported in the patupilone 7.5 mg/m2 group, in a pt with unknown primary previously treated with paclitaxel/carboplatin/VP-16. Most frequent G3/4 adverse events (AEs) were diarrhea 28%, thrombopenia 21%, neutropenia 14% and asthenia 14%. So far 14 pts are evaluable for tumor response: 1 confirmed and 2 unconfirmed PR, 4 SD and 7 PD were reported. Updated results and PK data will be presented. Conclusion: Preliminary results suggest that patupilone doses up to 7.5 mg/m2 combined with carboplatin have an acceptable toxicity profile with evidence of anti- tumor activity. Author Disclosure Employment or Leadership Consultant or Advisory Role Stock Ownership Honoraria Research Expert Testimony Other Remuneration Novartis AstraZeneca Oncology, Genentech™ BioOncology, Pfizer Oncology, Roche, Takeda Aventis, Genentech Inc., GlaxoSmithKline, Novartis Genentech Inc., Novartis Novartis
THE ORIGIN OF LIFE.
Journal: JAMA (2007)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pre-op
Authors: Geri Rosenzweig
Journal: Annals of Internal Medicine (1996)

Ad Libitum15 July 1996Pre-opGeri Rosenzweig, RNGeri Rosenzweig, RNChappaqua, NY 10514Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-125-2-199607150-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Smocked in blue,nurses flock to my bodyas the snows of Aprilfeather the bud;wildflowers of allergiesblossom againin margins of charts,petals of blood flutterfrom a vine tappedin my arm;measuring a scar beddedlike a briar in my side,they question whyearth took father too soon,why mother still loiters on the road;the voice of my heart arrives on a flowing graph,music piped from a russet hill;snow glazes the sill when they leave me,a plot of earth swept cleanfor the hooded strangerwho comes with a keen knifeto prune the dark rootsprouting on my kidney;I'm quiet as a crocus ... Author, Article, and Disclosure InformationAffiliations: Chappaqua, NY 10514Corresponding Author: Geri Rosenzweig, RN, 44 Deerfield Road, Chappaqua, NY 10514. Previousarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byDifferences in breast carcinoma characteristics in newly diagnosed African–American and Caucasian patients 15 July 1996Volume 125, Issue 2Page: 151KeywordsAllergy and immunologyBloodChartsGlomerulonephritisHeartScars ePublished: 15 August 2000 Issue Published: 15 July 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
CONCERNING MERCURIAL EXANTHEMATA AND IDIOSYNCRASY TO MERCURY.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phase II Explorative Study of Intermittent Imatinib (IM) Treatment (INTERIM) in Elderly Patients with Ph+ Chronic Myeloid Leukemia (CML) Who Achieved a Stable Complete Cytogenetic Response (CCgR) with Standard IM Therapy
Authors: Domenico Russo, Michele Malagola, Chiara Colombi, Massimo Breccia, Miriam Fogli, Piero Galieni, Giovanni Martinelli, Salvatore Mirto, Umberto Vitolo, Elisabetta Abruzzese, Giuliana Alimena, Monica Bocchia, Angelo Michele Carella, Fabrizio Pane, Gianantonio Rosti, Giuseppe Saglio, Giorgina Specchia, Michele Baccarani
Journal: Blood (2008)
The occurrence of chlamydial and gonococcal salpingitis during the menstrual cycle
Authors: R. L. Sweet
Journal: JAMA (1986)

We evaluated 104 women hospitalized with a diagnosis of acute salpingitis to compare the relationship between the menstrual cycle and onset of acute chlamydial and/or gonococcal salpingitis and acute salpingitis associated with other facultative aerobic and anaerobic bacteria.<i>Neisseria gonorrhoeae</i>was recovered from 42 women (40%),<i>Chlamydia trachomatis</i>from 28 (27%), and nongonococcal, nonchlamydial organisms only from the upper genital tract in 48 (46%). Among 37 cases with symptoms of acute salpingitis within seven days of onset of menses, 30 (81%) had chlamydial and/or gonococcal infection. Of 35 cases with onset after 14 days postmenses, 23 (66%) had nongonococcal, nonchlamydial organisms only. Of the 28 women with chlamydial infection, 17 (57%) had the onset of disease within one week from the first day of their last menstrual period. Similarly, 23 (55%) of gonococcal infections had onset of symptoms within one week from onset of menses. However, only seven (14%) of the women with nongonococcal, nonchlamydial salpingitis reported onset of symptoms within one week. The temporal pattern of onset of chlamydial or gonococcal acute salpingitis showed significant differences when compared with the time of onset for nongonococcal, nonchlamydial acute salpingitis. (<i>JAMA</i>1986;255:2062-2064)
VALUE OF GRATUITOUS MEDICAL TREATMENT CAN NOT BE RECOVERED.
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PROGRESS IN CHILD LABOR LAWS.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Carcinoma of the mammary crease. A neglected clinical entity
Authors: J. R. Watson
Journal: JAMA (1969)

Few cases of carcinoma of the mammary crease appear in the literature. Seven such cases from a series of 402 consecutive breast carcinomas emphasize several characteristics of this disease. The lesion initially resembles a callus and its significance is usually overlooked, which leads to delayed diagnosis and therapy. Although it is frequently ulcerated with underlying fascial fixation, radical "curative" surgery in selected cases is justified.
Seventeenth Annual Report of the State Board of Health of New York.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 123: Role of Valsartan (V) Alone or in Combination with Simvastatin (S) in Reducing Inflammation of Thin Cap Fibroatheromas
Authors: Yiannis S Chatzizisis, Michael Jonas, Ahmet U Coskun, Roy Beigel, Benjamin V Stone, Charles Maynard, Ross G Gerrity, William Daley, Campbell Rogers, Elazer R Edelman, Charles L Feldman, Peter H Stone
Journal: Circulation (2007)

Objectives: We investigated the role of V alone or in combination with S on the histomorphologic characteristics of thin cap fibroatheromas (TCFAs), and tested the hypothesis that V or VS attenuate the proinflammatory effect of low endothelial shear stress (ESS). We used vascular profiling of swine coronary arteries for in vivo assessment of ESS to prospectively identify these low ESS areas that are prone to develop TCFAs. Methods: 12 diabetic hyperlipidemic swine were allocated into 3 treatment groups: placebo (P, n=4), V (n=4) and VS (n=4). Blood pressure, serum cholesterol and glucose were similar between the treatment groups. IVUS-based geometrically correct 3D reconstruction of the coronary arteries was performed at baseline (wk 23) and follow up (wk 30). Baseline ESS was calculated using computational fluid dynamics and plaque-free subsegments of interest were identified (n=109). Coronary arteries (n=31) were harvested at follow up, cryosectioned at the subsegments of interest and stained histologically. Intima/media ratio and inflammation (CD45) were quantified. Lesions were classified into atheromas without evidence of fibrous cap (n=82) and TCFAs (n=60). Results: V alone or in combination with S reduced the amount of plaque inflammation, particularly in TCFAs (Fig A ). V and VS attenuated the proinflammatory effect of local low ESS compared to P (Fig B ). Conclusion: V alone or in combination with S exerts a stabilizing effect of reducing plaque inflammation, even in high-risk regions with low ESS. These results suggest a mechanism of regional atheroprotection associated with V or VS.