tbuckley/cabot-search huggingface dataset:
Pesticides in baby food.
Journal: Environmental Health Perspectives (1995)

We all worry about the population explosion-but we don't worry about it at the right time.Arthur Hoppe, attributed ForumPesticides in Baby FoodSixteen pesticides have been detected in eight brand-name baby foods, according to a study by the Environmental Working Group and the National Campaign for Pesticide Policy Reform, two public inter- est groups based in Washington, DC.In their study, the EWG and the NCPPR collected a random sampling of 76 jars of baby food from grocery store shelves in Denver, Philadelphia, and San Francisco.The group chose fruits and vegetables babies most commonly eat during their first year of life.Of these, 53% har- bored traces of one pesticide, and 18% had two or more pesticides.Plums contained the highest amounts at 46 parts per billion and peaches contained 29 parts per billion.Pears had the highest number of multiple pesticides overall (five).The report, Pesticides in Baby Food, was published in July by the EWG and the Tides Foundation (available on the World Wide Web at: http://www.ewg.org) and indicates that all levels of pesticides found were below federal standards.While these standards are set with safety considerations for infants, children, and other sensitive populations, the actual risk assessments are based on an average adult.According to the EWG, the concern is that pesticides are not currently "tested for safety in the way babies are exposed to them," and that babies and young children "react differently than adults to many drugs and toxic substances."These findings are consistent with the conclusions of a five-year investigation by Baby beware.Samples of common baby food Philadelphia, and San Francisco revealed that 53% h pesticide and 18% had two or more pesticides.
Notices
Authors: A Gressner, I Castillo
Journal: Hepatology (1992)

This conference is cosponsored by the American College of Physicians and Rush-Presbyterian-St. Luke's Medical Center, Chicago.The course will emphasize how basic physiology, biochemistry, pathophysiology and histopathology can be used to assist the physician in understanding, evaluating and treating patients with gastrointestinal and hepatobiliary diseases.The mechanisms of disease will be considered from clinical and
Blood Pressure in Older Adults after Meals and Standing Up
Journal: Annals of Internal Medicine (2000)

Summaries for Patients3 October 2000Blood Pressure in Older Adults after Meals and Standing UpSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-133-7-200010030-00006 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Fainting (syncope) and falls are common in older persons and can result in significant health problems, disability, and even death. With aging, the heart and circulation begin to respond in ways that predispose older persons to fainting and falls, including decreases in blood pressure on standing up (orthostatic hypotension) and after eating (postprandial hypotension). While these changes are thought to be potential factors in syncope and falls in the elderly, few detailed studies of this problem have been done.Why did the researchers do this particular study?To ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Upright Posture and Postprandial Hypotension in Elderly Persons.” It is in the 3 October 2000 issue of Annals of Internal Medicine (volume 133, pages 533-536). The authors are MS Maurer, W Karmally, H Rivadeneira, MK Parides, and DM Bloomfield.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoUpright Posture and Postprandial Hypotension in Elderly Persons Mathew S. Maurer , Wahida Karmally , Harold Rivadeneira , Michael K. Parides , and Daniel M. Bloomfield Metrics 3 October 2000Volume 133, Issue 7Page: I-48KeywordsBlood pressureEatingElderlyFallsHeartHeart rateHypotensionPostural controlResearch laboratoriesSyncope ePublished: 3 October 2000 Issue Published: 3 October 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Safety and Efficacy of Sulfamethoxazole and Trimethoprim Chemoprophylaxis for Pneumocystis carinii Pneumonia in AIDS
Authors: Margaret A. Fischi
Journal: JAMA (1988)

The safety and efficacy of sulfamethoxazole and trimethoprim in the prevention of<i>Pneumocystis carinii</i>pneumonia associated with the acquired immunodeficiency syndrome (AIDS) were evaluated. Sixty patients with a new diagnosis of Kaposi's sarcoma and no history of opportunistic infections were randomly assigned to receive 800 mg of sulfamethoxazole and 160 mg of trimethoprim twice per day or no therapy. None of the 30 patients receiving sulfamethoxazole and trimethoprim developed<i>P carinii</i>pneumonia. Sixteen of the 30 patients receiving no suppressive therapy developed<i>P carinii</i>pneumonia. Development of<i>P carinii</i>pneumonia was associated with the stage of Kaposi's sarcoma, B subtype disease, and the presence of 0.20 × 109/L (200/mm<sup>3</sup>) or fewer CD4 cells at study entry. The proportion of patients surviving and the mean length of survival were significantly greater in the treatment group compared with the control group. Adverse reactions occurred in 15 patients (50%). (<i>JAMA</i>1988;259:1185-1189)
Hutchison and Rainy's Clinical Methods.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
EDITORIAL
Journal: British Journal of Sports Medicine (1976)

As this editorial is written, it is interrupted by televised events from Austria, as the skill and artistry of the Winter Olympic Games makes compelling viewing that seems to take precendence over any other activity.Great Britain has been represented in most events, rightly so, as the promotion of methods of travel in icy conditions into competitive sports was predominantly a venture of Empire-building Victorian gentlemen who opened up hostile terrain as a winter playground.As in most sports we developed, other nations are winning the medals, putting up magnificent performances that can only be the result of intensive and prolonged training, and using vehicles such as bob-sleighs whose cost far outstrips anything we can afford.
Rapid Responses to Avapritinib (BLU-285) in Mastocytosis
Journal: Cancer Discovery (2017)

In a phase I trial of avapritinib (formerly BLU-285), which targets D816V mutant KIT, for the treatment of advanced systemic mastocytosis, patients experienced rapid and durable disease control. The overall response rate was 72%, and 56% of patients experienced a complete or partial response. No patients discontinued treatment due to adverse events, most of which were mild to moderate in nature.
Misdiagnosis of New Bifascicular Block
Authors: John E. Madias
Journal: Circulation (1999)

Hogue et al 1 concluded: "In the hour before AF [atrial fibrillation] after CABG surgery, higher heart rate and lower heart rate complexity compared with values in control patients were independent predictors of AF." Their careful study and stochastic analyses showed that this was statistically significant, but their observations were not clinically significant for the following reasons.After CABG operations, many patients have AF for a few minutes or hours without a fast ventricular rate or emboli.Even new AF that lasts for a day or more usually disappears spontaneously without bad results.In a series of 100 consecutive patients who had cardiac operations, all patients who entered the hospital in regular sinus rhythm left the hospital in regular sinus rhythm in spite of intervening AF. 2 Predicting harmless as well as harmful AF as a single set does not influence treatment or help the patients in other ways.Concerning patients who acquire AF after acute myocardial infarction (MI), the American College of Cardiology/American Heart Association stated, "Although AF after acute MI is usually transient, heparin therapy should be given to patients not already receiving it." 3Hogue et al 1 reported 1 patient who had AF and then appeared to have a fatal cerebral embolism on postoperative day 2.There was time to give this patient heparin, and the patient probably received it.Predicting that the patient would have AF would not have helped.Predicting which patients will have persistent hazardous AF is a different matter.Such a prediction would justify vigorous treatments in these few patients to prevent AF.Such treatment would not be reasonable for all patients at risk for this arrhythmia after CABG operations.
Abstract 1489: Increased levels of systemic LPS-positive bacterial extracellular vesicles in cancer patients with chemotherapy-induced intestinal barrier dysfunction
Authors: Joeri Tulkens, Olivier De Wever, An Hendrix
Journal: Cancer Research (2019)

Abstract Bacterial extracellular vesicles (EV) are nanometer-sized membrane particles transporting nucleic acids, metabolites, proteins and endotoxins (lipopolysaccharide (LPS)). As such, bacterial EV that enter the systemic circulation may deliver and elicit a variety of immunological and metabolic responses in different organs including the brain. To date, the systemic presence and activity of bacterial EV in patients with intestinal barrier dysfunction have not been investigated. We combined size exclusion chromatography and density gradient (DG) centrifugation to fractionate plasma LPS in two dimensions to separate bacterial EV-associated LPS from other LPS products. We evaluated plasma from healthy donors asymptomatic of intestinal barrier dysfunction versus cancer patients with radiation- or chemotherapy (with or without gastrointestinal mucositis). We quantitatively measured bacterial EV-associated LPS and other LPS products by performing Limulus Amebocyte Lysate (LAL) and Toll-like receptor 4 (TLR4) reporter assays and qualitatively confirmed the results by immunoelectron microscopy. LAL analysis of DG fractions corresponding to the density of bacterial EV, demonstrated significantly increased LPS activity in patients diagnosed with therapy-induced gastrointestinal mucositis compared to respective controls. In accordance, we detected elevated amounts of microbial pattern recognition receptor (PRR) ligands by determining TLR4 agonistic activity. Immunoelectron microscopy confirmed bacterial EV-associated LPS. In conclusion, LPS-positive bacterial EV are present in plasma, and correlate with impaired barrier integrity in cancer therapy-induced intestinal mucositis. Further studies are needed to understand systemic functions of circulating bacterial EV in cancer patients and cancer therapy-induced conditions. Citation Format: Joeri Tulkens, Olivier De Wever, An Hendrix. Increased levels of systemic LPS-positive bacterial extracellular vesicles in cancer patients with chemotherapy-induced intestinal barrier dysfunction [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1489.
Slow Season
Authors: Ted McMahon
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Therapy vs no therapy for bacteriuria in elderly ambulatory nonhospitalized women
Authors: J. A. Boscia
Journal: JAMA (1987)

This prospective randomized study was undertaken to determine the efficacy of antimicrobial therapy compared with no therapy for bacteriuria in elderly ambulatory nonhospitalized women. Sixty-one women (mean age, 85.8 years) with bacteriuria were in the no therapy control group and 63 women (mean age, 85.8 years) with bacteriuria were in the therapy group; none had symptoms of urinary tract infection. One short course of antimicrobial therapy achieved a cure rate of 68.3% (43 of 63 women cured) two weeks after treatment. During the six-month follow-up period, ten (16.4%) of 61 women in the no therapy group and five (7.9%) of 63 women in the therapy group developed symptomatic urinary tract infection. At the time of six-month follow-up, 19 (34.5%) of 55 women in the no therapy group and 35 (63.6%) of 55 women in the therapy group did not have bacteriuria. We conclude that for asymptomatic bacteriuria in elderly ambulatory nonhospitalized women, short-course antimicrobial therapy is effective at two-week follow-up and that antimicrobial therapy can eliminate bacteriuria in most of these women for at least a six-month period. (<i>JAMA</i>1987;257:1067-1071)
Opinion Leaders vs Audit Feedback to Implement Practice Guidelines-Reply
Authors: Jonathan Lomas
Journal: JAMA (1991)

<h3>In Reply.</h3> —Dr Ellerbeck suggests that only the opinion leaders generated the changes seen in the OLE group and, in any event, the information provided to the OLE group may have improved compliance without the use of opinion leaders. Both are potentially valid criticisms of opinion leader strategies; neither, however, appears to apply to this study. The opinion leaders managed only 30.4% of the eligible cases and, as stated in the article, "in no community did the opinion leader have the highest compliance rates." If the opinion leaders are removed from the analysis, the trial of labor and vaginal birth rates in the OLE group are, respectively, 33.1% and 21.6%—clearly, therefore, a community-wide phenomenon. The design of the OLE intervention was based on existing research demonstrating that the isolated provision of even nontraditional educational material fails to improve practice.<sup>1-3</sup>We see no reason why our study would have been
Health Law
Authors: Lawrence O. Gostin
Journal: JAMA (1992)

A 19th-century writer noted that "the science of legislation is like that of medicine in one respect: that it is far more easy to point out what will do harm than what will do good."<sup>1</sup>The continued retrenchment of the constitutional right to medical privacy for physicians and their patients emerged last year as distinctly harmful. The US Supreme Court has, case by case, limited the scope of medical privacy in the area of reproductive rights. Since<i>Roe v Wade</i>, the Court has upheld the authority of the state to withhold public funds<sup>2</sup>and to restrict the use of public employees and facilities for the performance of nontherapeutic abortions.<sup>3</sup>The right to privacy in other fields has been undermined as well.<sup>4</sup> The Supreme Court in<i>Rust v Sullivan</i><sup>5</sup>upheld a Department of Health and Human Services (DHHS) regulation prohibiting federally funded family planning clinics from
There's no free lunch. The benefits and risks of technologies
Authors: W. R. Hendee
Journal: JAMA (1991)

Nuclear energy and ionizing radiation are technologies that frequently are viewed with special concern by the public. Alarm often is expressed when these technologies are used for purposes such as generation of electrical power, exploration of material properties, and development of military weapons. Exposure to ionizing radiation is particularly troublesome because the risks are due to forces outside the range of the human senses. Radiation frequently is portrayed by the entertainment and news media as a technology that causes horrific effects as a result of exposure. We have all experienced this portrayal in movies, on television, and in popular literature.<sup>1</sup>As a consequence, few (if any) of us are totally objective in evaluating radiation, irrespective of our scientific and medical understanding. Certainly the average person does not view this technology objectively. Of course, exposure to ionizing radiation does entail risks. We have known about the adverse consequences of exposure
CHOLERA PREVENTION.
Authors: C. C. Fite
Journal: JAMA (1883)

Nashville, August 10, 1883. <h3>Editor Journal of American Medical Association,</h3><h3>My Dear Doctor:</h3> The Journalof July 28 has an excellent letter on cholera from Dr. H. Raymond Rogers, of Dunkirk, N. Y.; but I beg leave to insist on it that such expressions as the following should be omitted from cholera articles: " We know this disease laughs at cordon sanitaire or quarantine." Now, it is time the profession had gotten over such free and easy statements. His excellent ideas on the pathology and treatment of cholera are marred by such a statement. Cholera is, in a broad sense, a contagious and infectious disease, and the world should be taught to admit it, and act accordingly. It is communicable by persons, by traps of all kinds, by water, through the mails, and perhaps through the air for short distances. It is useless to cite authorities to prove this; it is
Chirurg, Berlin
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
VITAMIN C AND AMINO ACID METABOLISM
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Library Services
Authors: P. J. BISHOP
Journal: Annals of Internal Medicine (1974)

Comments1 June 1974Library ServicesP. J. BISHOPP. J. BISHOPSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-80-6-781_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: In his valuable article, "Searching the Literature Comes Before Writing the Literature" (Ann Intern Med 79:917-924, 1973), Beatty has given readers a masterly survey, and by producing such an admirable chart of what are now the rather crowded waters of medical bibliography and indexing, he has placed all users of medical libraries (both readers and librarians) in his debt.I would, however, like to mention one aspect of the problem he did not mention. This is the importance of the reader ascertaining if the library he is using undertakes any documentation, or recording of references, either in... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cardiothoracic Institute British Postgraduate Medical Federation University of London Brompton, London SW3 6HP PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 June 1974Volume 80, Issue 6Page: 781-781KeywordsChartsLibraries Issue Published: 1 June 1974 PDF DownloadLoading ...