Update in Gastroenterology
Authors: Norton J. Greenberger
Journal: Annals of Internal Medicine (1999)

Updates from the Annual Session21 September 1999Update in GastroenterologyNorton J. Greenberger, MDNorton J. Greenberger, MDFrom University of Kansas Medical Center, Kansas City, Kansas.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-131-6-199909210-00010 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Among the most important topics attracting investigators' attention in 1998 were gastroesophageal reflux disease (GERD), the diagnosis and treatment of Helicobacter pylori infection, and how best to manage patients with nonulcer dyspepsia. Also worthy of note are reports on the treatment of gastrointestinal bleeding, several aspects of inflammatory bowel disease, chronic pancreatitis, and colonic gas.Gastroesophageal Reflux DiseaseGastroesophageal reflux disease is widely prevalent, affecting roughly 7% of the U.S. population on a daily basis. Many other people are bothered by heartburn every week or month. Perhaps one fourth of all Americans use antacids at least twice a month. Relatively ...References1. Blustein PK, Beck PL, Meddings JB, Van Rosendaal GM, Bailey RJ, Lalor E, et al . The utility of endoscopy in the management of patients with gastroesophageal reflux symptoms. Am J Gastroenterol. 1998;93:2508-12. CrossrefMedlineGoogle Scholar2. Clavé P, González A, Moreno A, López R, Farré A, Cussó X, et al . Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors. Gastroenterology. 1998;115:597-604. CrossrefMedlineGoogle Scholar3. Kuipers EJ, Lundell L, Klinkenberg-Knol EC, Havu N, Festen HP, Liedman B, et al . Atrophic gastritis and Helicobacter pylori infection in patients with reflux esophagitis treated with omeprazole or fundoplication. N Engl J Med. 1996;334:1018-22. CrossrefMedlineGoogle Scholar4. Friedman LS. Helicobacter pylori and nonulcer dyspepsia [Editorial]. N Engl J Med. 1998;339:1928-30. CrossrefMedlineGoogle Scholar5. Rockey DC, Koch J, Cello JP, Sanders MP, McQuaid K. Relative frequency of upper gastrointestinal and colonic lesions in patients with positive fecal occult-blood tests. N Engl J Med. 1998;339:153-9. CrossrefMedlineGoogle Scholar6. McLeod RS, Wolff BG, Steinhart AH, Carryer PW, O'Rourke K, Andrews DF, et al . Risk and significance of endoscopic/radiological evidence of irregular Crohn's disease. Gastroenterology. 1997;113:1823-7. CrossrefMedlineGoogle Scholar7. Greenberger NJ. Update in gastroenterology. Ann Intern Med. 1998;129:309-16. LinkGoogle Scholar8. Targan SR, Hanauer SB, van Deventer SJ, Mayer L, Present DH, Braakman T, et al . A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med. 1997;337:1029-35. CrossrefMedlineGoogle Scholar9. Yacyshyn BR, Bowen-Yacyshyn MB, Jewell L, Tami JA, Bennett CF, Kisner DL, et al . A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease. Gastroenterology. 1998;114:1133-42. CrossrefMedlineGoogle Scholar10. Fine KD, Lee EL. Efficacy of open-label bismuth subsalicylate for the treatment of microscopic colitis. Gastroenterology. 1998;114:29-36. CrossrefMedlineGoogle Scholar11. Sharer N, Schwarz M, Malone G, Howarth A, Painter J, Super M, et al . Mutation of cystic fibrosis gene in patients with chronic pancreatitis. N Engl J Med. 1998;339:645-52. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From University of Kansas Medical Center, Kansas City, Kansas.Corresponding Author: Norton J. Greenberger, MD, Department of Internal Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160; e-mail, [email protected]edu. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUpdate in Hospital MedicineFranklin A. Michota Jr, MD 21 September 1999Volume 131, Issue 6Page: 445-452KeywordsBileBismuthColonCrohn's diseaseCystic fibrosisDrugsEsophagogastroduodenoscopyGastroesophageal reflux diseaseHemorrhageInflammatory bowel disease Issue Published: 21 September 1999 Copyright & PermissionsCopyright © 1999 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...