tbuckley/cabot-search huggingface dataset:
Recovery of hypoxic neonatal hearts after cardioplegic arrest
Authors: M. SAMAJA, A. CORNO
Journal: Cardiovascular Research (1993)

Journal Article Recovery of hypoxic neonatal hearts after cardioplegic arrest Get access MICHELE SAMAJA, MICHELE SAMAJA Search for other works by this author on: Oxford Academic PubMed Google Scholar ANTONIO CORNO ANTONIO CORNO Search for other works by this author on: Oxford Academic PubMed Google Scholar Cardiovascular Research, Volume 27, Issue 11, November 1993, Pages 2083–2084, https://doi.org/10.1093/cvr/27.11.2083a Published: 01 November 1993
TEMPORAL CHANGES IN SECONDARY PREVENTION AND CARDIOVASCULAR OUTCOMES AFTER REVASCULARIZATION FOR PERIPHERAL ARTERIAL DISEASE IN DENMARK: NATIONWIDE COHORT STUDY
Authors: Peter Brønnum Nielsen, Flemming Skjøth, Nikolaj Eldrup, Torben Bjerregaard Larsen, Mette Søgaard
Journal: Journal of the American College of Cardiology (2020)
SOCIETY NEWS.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Booknote
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reduction in Alcohol-Related Traffic Fatalities—United States, 1990-1992
Journal: JAMA (1994)

Alcohol-related traffic crashes are a leading cause of unintentional injury deaths and a substantial contributor to health-care costs in the United States. Approximately 40% of persons will be involved in an alcohol-related crash during their lifetime. In 1992, alcohol was involved in an estimated 17,700 traffic fatalities and 355,000 traffic injuries. In 1990, alcohol-related crashes cost $46.1 billion, including $5.1 billion in medical expenses. This report summarizes data regarding alcohol-related traffic fatalities (ARTFs) from the National Highway Traffic Safety Administration's (NHTSA) Fatal Accident Reporting System (FARS) during 1982-1992.
From the Food and Drug Administration
Authors: S. L. Nightingale
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
OPEN SAFETY PIN SUCCESSFULLY REMOVED FROM THE ESOPHAGUS BY PERORAL ENDOSCOPY
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Agranulocytosis
Authors: D. G. Wraith, F. D. Hart
Journal: BMJ (1955)

A 58-year-old man underwent upper gastrointestinal surveillance endoscopy for Barrett’s oesophagus. This showed a possible gastric ulcer, although histological examination was normal. Follow-up endoscopy showed white ridges in the distal duodenum and these were subjected to biopsy. Histological examination of the biopsy specimens showed polypoid duodenal mucosa showing features similar to those of a hyperplastic polyp of the colon. In addition, the mucosal surface was focally of gastric surface type. The features were interpreted overall as most likely to represent an unusual form of regenerative change in the setting of previous chronic inflammatory mucosal damage. The case is presented as an unusual histological phenomenon at this site; it would be important not to overdiagnose neoplasia in this situation.
Therapeutic approaches to allergic rhinitis: Treating the child
Authors: P FIREMAN
Journal: Journal of Allergy and Clinical Immunology (2000)

Allergic rhinitis is currently the most common of all chronic diseases in children. However, children frequently lack the ability to verbalize their symptoms, with the result that the condition may go undiagnosed and untreated. Unfortunately, untreated allergic rhinitis not only detrimentally affects children's physical and psychosocial well-being, quality of life, and capacity to function and learn, but it is also associated with and may contribute to potentially serious sequelae, including asthma, sinusitis, and otitis media. Because children may not accurately describe their symptoms, the classic signs of allergic rhinitis in the pediatric population, including the allergic shiner, the allergic crease, and the allergic salute, are particularly important in enabling the clinician to recognize those children who may have this condition; other significant signs include mouth breathing, snoring, chronic cough, and continual throat clearing. The options for treating allergic rhinitis in the child are the same as those for the adult, and the clinician can expect the same level of efficacy. Environmental control for allergen avoidance is an important goal, but the clinician must prescribe it within the context of the family's lifestyle to obtain compliance. Complete avoidance of inhalant allergens is not always feasible, and medications are necessary. Oral antihistamines remain the mainstay of initial treatment for allergies. Given evidence of the significant deleterious effects of the sedating antihistamines on learning, the clinician should prescribe nonsedating second-generation agents whenever possible. Decongestants may be needed. Intranasal corticosteroids are a most effective option, and these agents lack the systemic side effects associated with orally administered steroids. In persistent disease, allergen immunotherapy injections may be considered. In all cases, the clinician should consider issues that are likely to influence compliance in the pediatric population. (J Allergy Clin Immunol 2000;105:S616-21.)
Comments on Extrapolation of Cancer Response from High Dose to Low Dose
Authors: Norton Nelson
Journal: Environmental Health Perspectives (1978)

In making judgments as to the cancer risk from low level exposure to carcinogens it is generally necessary to base these judgments on high dose or high incidence data from laboratory or epidemiological studies. The biological considerations involved in making such extrapolations are discussed, as well as some of the mathematical procedures. The difficulties presented by moving from species to species, or from differently acting carcinogenic agents is considered.
Treatment of Fever in Hospitalized Patients with Low White Blood Cell Counts
Journal: Annals of Internal Medicine (2002)

Summaries for Patients16 July 2002Treatment of Fever in Hospitalized Patients with Low White Blood Cell CountsSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-2-200207160-00001 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Types of cancer, such as leukemia, and the therapies used to treat them (for example, chemotherapy and bone marrow transplants) often decrease the numbers of white blood cells in the body. White blood cells fight bacterial, fungal, and viral infections. Most patients with cancer who have few white blood cells have very weak immune systems and can't fight infections well. They get infections easily and, as a result, can die, particularly if the infections are not recognized early and treated. Fever is usually one of the earliest signs ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Ciprofloxacin plus Piperacillin Compared with Tobramycin plus Piperacillin as Empirical Therapy in Febrile Neutropenic Patients. A Randomized, Double-Blind Trial.” It is in the 16 July 2002 issue of Annals of Internal Medicine (volume 137, pages 77-86). The authors are JE Peacock Jr, DA Herrington, JC Wade, HM Lazarus, MD Reed, JW Sinclair, DC Haverstock, SF Kowalsky, DD Hurd, DA Cushing, CP Harman, and GR Donowitz.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCiprofloxacin plus Piperacillin Compared with Tobramycin plus Piperacillin as Empirical Therapy in Febrile Neutropenic Patients James E. Peacock Jr. , Deirdre A. Herrington , James C. Wade , Hillard M. Lazarus , Michael D. Reed , Jane W. Sinclair , Daniel C. Haverstock , Steven F. Kowalsky , David D. Hurd , Deborah A. Cushing , Colleen P. Harman , and Gerald R. Donowitz Metrics 16 July 2002Volume 137, Issue 2Page: I-20KeywordsAntibioticsAntifungalsBlood countsBone marrowDrugsFeversPatientsSafetyVeinsWhite blood cells ePublished: 16 July 2002 Issue Published: 16 July 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
SURGERY AND FATAL PULMONARY EMBOLISM
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hepatic biochemical changes as a result of acute cocaine administration in the mouse
Authors: C Boyer
Journal: Hepatology (1991)

The biochemical mechanism of cocaine hepatotoxicity is thought to involve enzymatic formation of reactive metabolites. The exact hepatocellular effects of these metabolites have yet to be established. This study was designed to monitor, in a time course after an acute cocaine dose, biochemical parameters that are important in cellular defense and homeostasis in vivo. The hepatic parameters measured were ATP as an indicator of cellular energetic status, reduced and oxidized glutathione, NADH and NADPH as measures of redox changes, and thiobarbituric acid–reactive products and microsomal conjugated dienes to determine the extent of lipid peroxidation. In addition, serum ALT levels were determined at each time point to assess the extent of toxicity. Inbred mouse strains selected for their relative sensitivity (male DBA/2Ibg) and resistance (male C57BL/6Ibg) to cocaine-mediated hepatotoxicity were used in this study. Animals were given an acute 50 mg/kg intraperitoneal dose of cocaine, and at various times after administration the hepatic and serum determinations were made. The results of this study confirm the strain difference in cocaine-induced hepatotoxicity and also indicate that there are changes in the biochemistry of the liver that are brought about by acute cocaine administration. In particular, depletions of hepatic GSH, NADH, NADPH and ATP coupled with significant increases in oxidized glutathione were observed in the DBA mouse. C57BL mice showed similar decreases in reduced glutathione, NADH and NADPH but exhibited no significant depletion of hepatic ATP. A similar extent of lipid peroxidation was seen in both mouse strains after cocaine administration. Differences in oxidized glutathione levels after cocaine administration were observed, indicating that an oxidative stress may occur in the DBA mouse to a significantly greater extent than the C57BL mouse. In addition, differences in the extent of ATP depletion suggest that cocaine-mediated disruption of cellular bioenergetics may be an important determinant of hepatotoxicity. (HEPATOLOGY 1991;14:1209–1216.)
Gastrointestinal bleeding
Authors: T. Marek
Journal: Endoscopy (2011)

Gastrointestinal bleeding remains one of the most important emergencies in gastroenterology. Despite this, only about 100 abstracts concerning gastrointestinal bleeding (excluding bleeding complicating endoscopic procedures) were presented at this year's Digestive Disease Week (DDW; 7 – 10 May 2011; Chicago, Illinois, USA), accounting for less than 2 % of all presented lectures and posters. It seems that the number of such abstracts has been decreasing over recent years. This may be due in part to the high level of medical care already achieved, especially in the areas of pharmacotherapy and endoscopic treatment of gastrointestinal bleeding. In this review of gastrointestinal bleeding, priority has been given to large epidemiological studies reflecting "real life," and abstracts dealing more or less directly with endoscopic management.
What is the Rationale of Traction and Counter-Traction in the Treatment of Hip-Disease.
Journal: JAMA (1883)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pulmonary Carcinogenicity of Inhaled Particles and the Maximum Tolerated Dose
Authors: G. Oberdorster
Journal: Environmental Health Perspectives (1997)

Chronic inhalation bioassays in rodents are used to assess pulmonary carcinogenicity for purposes of hazard identification and potentially for risk characterization.The influence of high experimental doses on tumor development has been recognized for some time and has led to the concept of maximum tolerated dose (MTD) for dose selection, with the highest dose being at the MTD.Exposure at the MTD should ensure that the animals are sufficiently challenged while at the same time the animal's normal longevity is not altered from effects other than carcinogenicity.A characteristic of exposure-dose-response relationships for chronically inhaled particles is that lung tumors are significantly increased only at high exposure levels, and that lung tumors are seen in rats only but not in mice or hamsters.This lung tumor response in rats is thought to be secondary to persistent alveolar inflammation, indicating that the MTD may have been exceeded.Thus, mechanisms of toxicity and carcinogenicity may be dose dependent and may not operate at lower doses that humans normally experience.Despite awareness of this problem, carcinogenicity bioassays that evaluate particulate compounds in rodents have not always been designed with the MTD concept in mind.This is due to several problems associated with determining an appropriate MTD for particle inhalation studies.One requirement for the MTD is that some toxicity should be observed.However, it is difficult to define what degree of toxic response is indicative of the MTD.For particle inhalation studies, various noncancer end points in addition to mortality and body weight gain have been considered as indicators of the MTD, i.e., pulmonary inflammation, increased epithelial cell proliferation, increased lung weight, impairment of particle clearance function, and significant histopathological findings at the end of a subchronic study.However, there is no general agreement about quantification of these end points to define the MTD.To determine whether pulmonary responses are indicative of the MTD, we suggest defining an MTD based on results of a multidose subchronic and chronic inhalation study with a known human particulate carcinogen, e.g., asbestos or crystalline silica.Quantification of effects in such a study using the noncancer end points listed above would identify a dose level without significant signs of toxicity at the end of the subchronic study.If this dose level still results in significant lung tumor incidence at the end of the chronic study.We will have a sound basis for characterizing the MTD and justifying its use in future particle inhalation studies.Also, a better understanding of cellular and molecular mechanisms of particle-induced lung tumors is needed to support the MTD concept.
Factors predicting the success of intradetrusor onabotulinum toxin-a treatment in children with neurogenic bladders due to myelomeningocele: The outcomes of a large cohort
Authors: Y.O. Danacioglu, F. Keser, C. Ersoz, S. Polat, A.E. Avci, S. Kalkan, M.S. Silay
Journal: European Urology (2021)
Adverse prenatal and perinatal factors are associated with schizophrenia of early onset
Journal: BMJ (1999)

Adverse prenatal and perinatal factors are associated with schizophrenia of early onsetIn order to investigate the role of prenatal and perinatal risk factors in the development of schizophrenia and affective and reactive psychosis in early adult life, Hultman et al (p 421) carried out three population based, case-control studies using the Swedish birth and inpatient registries.Adverse prenatal and perinatal factors were more common in patients with schizophrenia than in controls and seemed more important in the aetiology of early onset schizophrenia than in affective and reactive psychosis.Multiparity, bleeding during pregnancy, and small size for gestational age were associated with a threefold to fourfold increased risk for schizophrenia among males.The authors conclude that the mechanism underlying the increased risk remains unknown but ischaemic brain damage secondary to placental insufficiency is one possibility.
In Brief
Authors: Cezmi Akdis, Bruce Beutler, Peter Cresswell, James Di, Gary Koretzky, Charles Mackay, J Cornelis, Michel Nussenzweig, Alan Sher, Andreas Strasser The, Walter And, Eliza Hall, Megan Sykes, Eric Vivier, Matthias Von Herrath
Journal: Nature reviews. Immunology (2005)