tbuckley/cabot-search huggingface dataset:
Dog-Bite—Related Fatalities—United States, 1995-1996
Journal: JAMA (1997)

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Leukocyte Reduction and Ultraviolet B Irradiation of Platelets to Prevent Alloimmunization and Refractoriness to Platelet Transfusions
Authors: The Trial to Reduce Alloimmunization to Platelets Study Group
Journal: New England Journal of Medicine (1997)

We conducted a multi-institutional, randomized, blinded trial to determine whether the use of platelets from which leukocytes had been removed by a filter or that had been treated with ultraviolet B irradiation would prevent the formation of antiplatelet alloantibodies and refractoriness to platelet transfusions.
ASYMPTOMATIC INTERMITTENT PROTEINURIA
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pulmonary Function Testing in Small Laboratory Mammals
Authors: John J. O'Neil, James A. Raub
Journal: Environmental Health Perspectives (1984)

The lung is the primary organ likely to be exposed by inhalation studies and, therefore, measurement of changes in lung function are of particular interest to the pulmonary physiologist and toxicologist. Tests of pulmonary function have been developed which can be used with small animals to measure spirometry (lung volumes), mechanics, distribution of ventilation, gas exchange or control of ventilation. These tests were designed on the basis of similar tests which are used in humans to diagnose and manage patients with lung disease. A major difference is that many of the measurements are performed in anesthetized animals, while human pulmonary function is usually measured in awake cooperating individuals. In addition, the measurement of respiratory events in small animals requires sensitive and rapidly responding equipment, because signals may be small and events can occur quickly. In general, the measurements described provide information on the change in normal lung function which results primarily from structural changes. These tests of pulmonary function can be repetitively and routinely accomplished and the results appear to be highly reproducible. Although some are quite sophisticated, many can be undertaken with relatively inexpensive equipment and provide useful information for toxicological testing.
Unveiling
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Smoking Behavior Partially Explains Socioeconomic Inequities in Lung Cancer Incidence
Authors: Caroline Mcneil
Journal: JNCI Journal of the National Cancer Institute (2009)

Europeans with the least education have a higher incidence of lung cancer compared with those with the highest education.However, smoking history accounts for approximately half of this risk, according to a study in the February 24 online issue of the Journal of the National Cancer Institute.Previous studies showed that individuals with a lower socioeconomic status have a higher risk for developing lung cancer.Some studies have also suggested that some of the excess risk of lung cancer is due to smoking.To further investigate the contribution of smoking to the discrepancy in lung cancer incidence, Gwenn Menvielle, Ph.D., and colleagues examined the association of smoking, diet, education, and lung cancer in 391,251 individuals in the European Prospective Investigation into Cancer and Nutrition study.Menvielle, who conducted the research in The Netherlands
Zinc metabolism in sickle cell anemia
Authors: H. B. Niell
Journal: JAMA (1979)

Zinc metabolism was studied in 34 patients with sickle cell anemia in a steady state and in six patients during sickle cell crisis. The patients in steady state were found to have significantly lower plasma levels and higher urinary levels of zinc than the 50 healthy adults in the control group. During sickle cell crisis the plasma zinc levels dropped to a mean value of 0.54 μg/mL from a steady state value of 0.79 μg/mL. These results support the concept that zinc deficiency occurs in sickle cell anemia and that further drops occur in the serum zinc levels during sickle cell crisis. (<i>JAMA</i>242:2686-2687, 1979)
Genes and Kidney Disease
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
RHEUMATISMAL METATARSAL OSTEOPERIOSTITIS.
Journal: JAMA (1888)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hemoglobin-Based Blood Substitutes and Risk of Myocardial Infarction and Death—Reply
Authors: Charles Natanson
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Uniform Format for Disclosure of Competing Interests in ICMJE Journals
Authors: Jeffrey M. Drazen, Martin B. Van Der Weyden, Peush Sahni, Jacob Rosenberg, Ana Marusic, Christine Laine, Sheldon Kotzin, Richard Horton, Paul C. Hébert, Charlotte Haug, Fiona Godlee, Frank A. Frizelle, Peter W. de Leeuw, Catherine D. DeAngelis
Journal: New England Journal of Medicine (2009)
SOCIAL WELFARE INVESTIGATIONS
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
This Week in &lt;emph&gt;JAMA&lt;/emph&gt;
Journal: JAMA (2011)

A Piece of My Mind"Even after working four years, it's still hard for me to talk about this study with friends, with family."From "Entering Data." SEE PAGE 1944 Medical News & PerspectivesNew studies find that coronary artery bypass graft surgery is no more effective than medical therapy in preventing death in patients with heart failure, prompting questions about the invasive procedure's value in this patient population.
It's important, but don't bank on exercise alone to prevent osteoporosis, experts say
Authors: A. Skolnick
Journal: JAMA (1990)

ALTHOUGH exercise is essential for building and maintaining sound bones, it is not a panacea for preventing osteoporosis, as portrayed by some reports in the lay news media, says Barbara L. Drinkwater, PhD, a research physiologist at Pacific Medical Center, Seattle, Wash. Relying on exercise instead of estrogen replacement therapy for postmenopausal women, who are at risk for developing osteoporosis, "is like playing Russian roulette with their bones," she warned at the Second International Research Advances in Osteoporosis Conference, in Arlington, Va. While ample evidence exists that long periods of immobility can lead to serious bone loss (irreversible bone loss also occurs during extended periods of weightlessness and is a serious problem confronting American and Soviet manned space programs), there is no evidence that intensive exercise will prevent the rapid bone loss many women experience during the first decade following menopause, Drinkwater says. <h3>Exercise and Estrogen?</h3> "If you look at
Incidence of Down's syndrome in Rhode Island
Authors: G. Barsel-Bowers
Journal: JAMA (1982)

<h3>To the Editor.—</h3> Using data from metropolitan Atlanta, Adams et al (1981; 246:758) have reported a decrease in the crude incidence of Down's syndrome from 1.33/1,000 births in 1960 to approximately 0.99/1,000 births in 1978. According to the authors, the explanation for this decrease is a reduction in the proportion of births to women aged 35 years or older. They suggest that estimates of resources for future services should be based on these data. We have been able to ascertain all cytogenetically proved cases of Down's syndrome live births in Rhode Island during 1976 to 1980. Since Rhode Island has only two cytogenetic laboratories where blood specimens for chromosomal analysis are routinely sent and one child development center where most children with Down's syndrome are followed up, we are confident that the ascertainment of all live-born children with Down's syndrome is as complete as can be achieved anywhere. Our demographic
Ampullary cancer ESPAC-3 (v2) trial: A multicenter, international, open-label, randomized controlled phase III trial of adjuvant chemotherapy versus observation in patients with adenocarcinoma of the ampulla of vater.
Authors: J. P. Neoptolemos, M. J. Moore, T. F. Cox, J. W. Valle, D. H. Palmer, A. Mcdonald, R. Carter, N. C. Tebbutt, C. Dervenis, D. Smith, B. Glimelius, F. Y. Coxon, F. Lacaine, M. R. Middleton, P. Ghaneh, C. Bassi, C. Halloran, A. Olah, C. L. Rawcliffe, M. W. Büchler
Journal: Journal of Clinical Oncology (2011)

LBA4006 The full, final text of this abstract will be available in Part II of the 2011 Annual Meeting Proceedings, distributed onsite at the Meeting on June 4, 2011, and as a supplement to the June 20, 2011, issue of Journal of Clinical Oncology.
Feisty gram-negative aerobes succumb to new antibiotic group
Authors: J. Henahan
Journal: JAMA (1982)

The organism<i>Chromobacterium violaceum</i>was living in relative obscurity in the swamps of southern New Jersey only three years ago. But the new man-made drug that its "discovery" inspired has already proved quite effective against<i>Pseudomonas aeruginosa</i>and other drug-resistant bacteria involved in hospital-acquired infections throughout the world. Called azthreonam, the first of the new "monobactam" antibiotics synthesized at the Squibb Institute for Medical Research, Princeton, NJ, received its first clinical airing at the Third Mediterranean Congress of Chemotherapy in Dubrovnik, Yugoslavia. It has shown considerable efficacy against resistant gram-negative infections of the urinary tract, lungs, bone, and soft tissue. It is also efficacious against penicillin-resistant strains of<i>Neisseria gonorrhoeae</i>. In 1979, Squibb scientists found that<i>C violaceum</i>produces substances that are weak antibiotics but are also highly resistant to the β-lactamase enzymes. Such enzymes have effectively neutralized the efficacy of the penicillins and some of the cephalosporin antibiotics against
Zur Klinik der nichtparalytischen Lues-Psychosen.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"Heartstart" Scotland.
Authors: H A Tait
Journal: BMJ (1991)

by repeat tests.At Brixton HIV positive prisoners, who are segregated because of their infection, occupy better accommodation, which thus encourages prisoners to claim that they are positive for the virus.Retesting shows that some of them are indeed negative.Injecting drug use undoubtedly occurs in prisons, particularly among remand prisoners, and sharing of equipment is inevitable.Although cases of acute hepatitis B in prison have been recorded, so far there has been no evidence of acute HIV seroconversion illness.In an American custodial prison HIV testing on admission and release has not shown significant changes in seropositivity.,Long term prisoners are much less likely to abuse drugs.Identification of those prisoners infected with HIV, with guaranteed confidentiality, will permit targeted advice on reducing the risk of trans- mitting the virus and on maximising current health, including detoxification of drug users.Tests to evaluate the immune system will enable appropriate prophylaxis to be prescribed to those who are vulnerable to sudden life threatening opportunistic infections.Multidisciplinary committees should be established to plan, implement, and monitor systems for managing HIV infection in British prisons.Sensitive and effective handling will benefit public health in general and the prison population in particular, including staff.
Reactions Between Blood Group Antibodies and Antisera to Purified Immunoglobulins
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Clinical and Translational Studies in Fibrosis
Journal: Hepatology (2013)

Background: Inflammatory bowel disease (IBD) is found to be associated with several kinds of liver disease.The purpose of this study is to investigate the role of combination with dextran sodium sulfate (DSS) in hepatitis and fibrosis in mice treated by with CCl4.Methods: Male C57BL/6 mice were grouped as follows: Control group (n=10), DSS group (n=10), Olive oil group (n=10), CCl4 group (n=10) and CCl4+DSS group (n=10).Severity of colitis was evaluated by disease activity index (DAI), colon length, colon pathology score, myeloperoxidase (MPO) and histopathology.Haematoxylin and eosin (H&E) staining, Sirius red staining and Masson's trichrome (MT) staining were used to detect liver histopathological changes.Pro-inflammatory cytokines in both colon and liver tissues including TNF-α, IFN-γ and IL-17A were detected by immunohistochemical staining, western blot and real-time Q-PCR, respectively.The protein and mRNA expressions of TGF-β1, α-SMA, collagen I, collagen III, MMP-2 and TIMP-2 in liver tissues were observed by immunohistochemical staining, western blot and real-time Q-PCR, respectively.Results: DSS treatment led to increased BW loss, higher DAI score, shortened colon length, elevated MPO activity, and worsened histologic inflammation in colon.Moreover, TNF-α, IFN-γ and IL-17A expressions in both colon and liver tissues were all enhanced in DSS group.Hepatitis was also found in DSS group as well as CCl4 group and CCl4+DSS group by histological analysis.However, comparing with CCl4 group, hepatitis in CCl4+DSS were more severe, reflected by histology and pro-inflammation cytokines expressions.Increased hepatic fibrosis was observed by Sirius red staining and MT staining, as well as higher levels TGF-β1, α-SMA, collagen I, collagen type III, TIMP-2 and lower level of MMP-2 in liver tissue.Conclusions: The DSS-induced mouse colitis may promote hepatic inflammation and fibrosis in mice treated by CCl4.