tbuckley/cabot-search huggingface dataset:
Medicare Part D low-income subsidy and disparities in breast cancer treatment.
Authors: Alana Biggers, Joan Neuner, Elizabeth Smith, Liliana Pezzin, Purushottam Laud, John A. Charlson, Alicia Smallwood
Journal: Journal of Clinical Oncology (2014)

6534 Background: Breast cancer outcomes are worse among black than white women, but the role of income and out-of-pocket costs (OOPCs) in these disparities is understudied. The Medicare D program provided medication insurance for older women and also included a low-income subsidy (LIS) which eliminated or reduced OOPCs among women with low assets and limited income (based on federal poverty level). We examined differences in adherence to HT by race/ethnicity among a Medicare D population, hypothesizing that LIS might reduce racial disparities in HT adherence. Methods: With data collected from a national sample of women enrolled in Medicare Parts A, B and D, we identified Medicare Part D enrollees ≥65 years diagnosed with breast cancer who underwent mastectomy or breast conserving surgery in 2006-07 and received either tamoxifen or an AI (anastrozole, letrozole, or exemestane) within one year of surgery. Non-adherence rates (medication possession rate of >0.80) were calculated by race and LIS status for each year after first fill up through December 2011. The association of race with HT adherence was examined in unadjusted Chi-square analyses and in regression models adjusted for age, comorbidity, chemotherapy use and zip code level- income and education. All models utilized GEE to account for within-patient clustering. Results: Among a sample of 23,299 women (50.6% age 65-74, 40.9% age 75-84), 27.2% received LIS. LIS (but not AI use) varied substantially by race, so that 20.6% of white women and 69.7% of black women received the subsidy. In the first year of therapy, differences in adherence by race were statistically significant, but small (79.3% for white, 78.1% for black and 80.9% for Hispanic). Adherence dropped during years 2-3 of the study, but reductions were much smaller among LIS recipients. Results were confirmed in adjusted models. Conclusions: Enrollment in the Medicare D LIS was high among black and Hispanic breast cancer patients, and disparities in adherence to breast cancer HT among these women were small and remained so over three years. Our study offers important information about the role of medication subsidies and SES in adherence, and suggests their potential to reduce the breast cancer outcomes gap by race.
Rab27a: a new face in cell metabolism-secretion coupling
Authors: T. Aizawa
Journal: Journal of Clinical Investigation (2005)

In pancreatic β cells, not only insulin exocytosis per se, but translocation of β granules toward the plasma membrane — an event upstream of exocytosis — are under the control of glucose. However, the molecular basis of this translocation has been poorly understood. Rab27a-mediated translocation of glucose-induced β granules is reported in this issue of the JCI. Rab27a or its effector molecule may constitute a novel pharmacological target because potentiation of the Rab27a pathway is expected to restore β cell glucose competency in patients with diabetes mellitus.
Incidence and characteristics of preventable iatrogenic cardiac arrests
Authors: S. E. Bedell
Journal: JAMA (1991)

We studied the contribution of iatrogenic illness to cardiac arrest among patients hospitalized in 1981 in a university teaching hospital. During this 1-year period, 28 (14%) of 203 arrests in which resuscitation was attempted followed an iatrogenic complication. Seventeen (61%) of the 28 patients died. The demographic characteristics of patients with iatrogenic arrest did not differ strikingly from those of other patients who arrested. However, patients with iatrogenic arrest were less likely to be in cardiogenic shock or to have suffered an acute myocardial infarction prior to arrest. They were more likely to survive to discharge from the hospital and to be taking digoxin or antiarrhythmic medication prior to arrest. Among the 28 cases of iatrogenic cardiac arrest, 18 (9% of all arrests) might have been prevented by stricter attention to the patient's history, findings on physical examination, and laboratory data. The most common causes of potentially preventable arrest were medication errors and toxic effects (44%) as well as suboptimal response by physicians to clinical signs and symptoms (28%), most frequently dyspnea and tachypnea. Rapid, appropriate response to abnormal drug levels, to electrocardiographic signs of adverse drug effects, and to signs and symptoms of congestive heart failure or toxic effects from digoxin might decrease the incidence of cardiac arrest among hospitalized patients. (<i>JAMA</i>. 1991;265:2815-2820)
<i>Errata</i>: Vol. 66 No. 34
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

In the report, "Notes from the Field: Lead Poisoning in an Infant Associated with a Metal Bracelet -Connecticut, 2016" on page 916, the second paragraph should have read "The parents reported that the child intermittently wore a handmade "homeopathic magnetic hematite healing bracelet" that they had purchased from an artisan at a local fair (Figure).The bracelet was described as "homeopathic," but homeopathic products are, by definition, regulated drugs and so nondrug items, such as bracelets, cannot be homeopathic.Cases of mislabeled products, especially among homemade items, should raise suspicion for consumers and health care professionals.The child wore the bracelet for teething related discomfort and was sometimes noted to chew on it.Small spacer beads from the bracelet tested at the Manchester Health Department were positive for lead (17,000 ppm).No identifying marks indicating metal content or manufacturer were found on the bead.The vendor records were not available, and the bracelet maker could not be located."
Recent trends in antimicrobial resistance among Streptococcus pneumoniae and Staphylococcus aureus isolates: the French experience
Authors: Collective Anonymous
Journal: Eurosurveillance (2008)

In France, the overall proportion of penicillin-non-susceptible Streptococcus pneumoniae has decreased from 53% in 2002 to 38% in 2006, and the proportion of methicillin-resistant Staphylococcus aureus from 33% in 2001 to 26% in 2007. Although the rates remain very high compared to northern European countries, these trends suggest that the prevention efforts implemented since 2000 through two national programmes (the national plan for preserving the efficacy of antibiotics and the national infection control programme) and updated recommendations for pneumococcal vaccination are successful.
Unreviewed Reports
Journal: BMJ (1985)

Unreviewed Reports Autophony in pregnancyAutophony is the name given to both the symptoms and the condition caused by excessive patency of the eustachian tube.Patients complain of hearing their breathing as a series of rushing or roaring sounds, and when they speak their voice has a loud booming quality in the affected ear.' Three women, aged between 30 and 35, complained ofautophony during the second trimester of pregnancy.The diagnosis was confirmed by otoscopic examination and im- pedance audiometry.All cases resolved spontaneously.Hormonal changes of pregnancy may alter the turgor of the eustachian cushion and thus predispose the patient to develop this condition.
Fiber Levels and Disease in Workers from a Factory Predominantly Using Amosite
Authors: A. R. Gibbs, M. J. Gardner, F. D. Pooley, D. M. Griffiths, B. Blight, J. C. Wagner
Journal: Environmental Health Perspectives (1994)

The Cape Boards Plant at Uxbridge produced insulation board containing amosite asbestos between 1947 and 1973 with only small amounts of chrysotile.After 1973 only amosite was used.In this study we examined lung samples from 48 workers who had been employed at the plant and who had come to autopsy.The study investigated the fiber levels against the lung pathology including amount of interstitial fibrosis and numbers of ferruginous bodies.The degree of interstitial fibrosis and number of asbestos bodies were graded and the tissues were analyzed by transmission electron microscopy and energy dispersive X-ray analysis and the fibers counted and typed.The 48 cases included 5 mesotheliomas and 14 lung cancers.The mineral analysis results were dominated by the amosite fiber levels.The amounts of chrysotile were relatively small.There were higher levels in lung cancer cases than mesotheliomas and higher levels in mesothelioma cases than those who had died from nonasbestos related diseases.Analysis of the lung tissues showed a consistent pattern of high amosite levels, which confirms the impression that amosite was the pre- dominant form of asbestos used and also indicates that the factory had been a very dusty one.-
Nonsurgical management of obstructive jaundice in the patient with advanced cancer
Authors: R. L. MacCarty
Journal: JAMA (1980)

CAUSES of malignant biliary obstruction include carcinoma of the pancreas, metastasis to portal lymph nodes, bile duct carcinoma, and carcinoma of the gallbladder. Unfortunately, most patients with such obstructions have incurable disease, so the physician's skills must be directed to prolonging and improving the quality of life. Pruritus, loss of weight, lipid malabsorption, hypoprothrombinemia, and sepsis are all manifestations of biliary obstruction. Adequate drainage of the obstructed biliary system can result in reversal of nutritional deficiencies, relief of pruritus, and clearing of infection. Untreated biliary obstruction leads to progressive hepatic failure, coma, and death. <h3>Surgical Biliary Drainage</h3> Choledochojejunostomy, cholecystojejunostomy, choledochoduodenostomy, hepaticojejunostomy, and operative placement of stent tubes and catheters have been used as palliative surgical drainage procedures. Unfortunately, patients with malignant biliary obstruction often poorly tolerate surgery and recuperate slowly. The operative mortality has been reported to be 10% to 20%.<sup>1,2</sup>Postoperative recovery may be prolonged by pneumonia, intra-abdominal
Value in Using CAR T Cells for DLBCL
Journal: Cancer Discovery (2017)

Abstract The phase II JULIET trial suggests that the CD19-targeting CAR T-cell therapy tisagenlecleucel produces durable responses in patients with relapsed and refractory diffuse large B-cell lymphoma. Three months after the therapy, 32% of the patients showed complete responses and 6% showed partial responses. After 6 months, those rates were 30% and 7%.
“Guide-wire Perforation during Bougienage and Tube Positioning. Report on Three Cases and Technical Improvement”
Authors: A. E. Hanwell, H. Kowalewski, med. Rösch
Journal: Endoscopy (1989)

See also: Guide-wire Perforation during Bougienage and Tube Positioning. Report on Three Cases and Technical ImprovementEndoscopy 1988; 20(06): 332-333DOI: 10.1055/s-2007-1013025
JAMA Psychiatry
Authors: Phil Fontanarosa, Annette Flanagin, Brenda Gregoline, Tracy Frey, Shannon Sparenga, Nicole Balin, Miriam Cintron, Paul Ruich, Diane Cannon, Connie Manno, Fred Marshall, Laura Copyreaders, Catherine Adamczyk, Stephanie Alden, Jan Beckmeyer, Mary Clavey, Paula Coerver-Connolly, Roya Glitman, Laura Khatiblou, Donna King, Caroline Thordsen, Wanda Assistant, Larry Bryant, Monica Mungle, Elaine Williams, Lenette Gardner-Gullens, Fanny Brown, Paul Frank, Peter Kim, Rachell Lozano, Michaela Mark, Kathryn Muskovich, Gale Saulsberry, Michael Berkwits, Michelle Kurzynski, Eric Butkus, Will English, Christopher Hastings, Craig Mccaffrey, Reuben Rios, Ronna Henry, Joshua Bird, Karen Bucher, David Song, Deputy Livingston, Thomas Cole, Marla Hall, Deanna Willis, Yolanda Davis, Joseph Thornton, Preeti Malani, Deanna Bellandi, Jim Periodical, Thomas Easley, Brian Shields, Monica Smith, Jeffery Bonistalli Manager, Kathy Russell, Mirna Monal, Stacey Mchugh, Thalia Moss, Mike Harvey, Susan Henning, Mark Thornbury, Tricia Castellano, Saskia Bolore, Gretchen Linder, Brian Mccartney, David Baum, Rebecca Haas, Christine Hearne, Irma Lara, Ron Marketing, Paul Gee, Matt Herron, Elizabeth Solaro, Geoffrey Flick Managers, Rick Bell, Lindsay Dawson, Michael Mcgraw, Sara Nagy, Romando Rossini, Stacy Staff, Millette Jackson-Bates, Karen Adams-Taylor, Karl Elvin, Sue Managers, David Antos, Chris Borden, Debbie Camp, Lydia Cruz, Scott Curl, Diane Darnell, Colleen Kelly, Chris Meyer, Jaye Mize, Annemarie Neff, J Neff, Sean O'donnell, Sean Ohlson, Phil O'leary, Susan Price, Denise Steinhauser, Production Services, Kim Boler, Rhonda Brown, Timothy Burke, Daniel Degroot, Jordynn Farrar, Euwanaha Joiner-Smith, Tiffany Jones, Cindy Rendlen, Ellen Yoshihara, Circulation Services, Julie Burton, Dexter Golden, Erin Hinchcliff, Maria Nienhaus, Noemi Rivera, Geneine Van, Someren Composition, New Media, Gail Barrett, Regina Brownlee, Amanda Camino, Brenda Chandler-Grayer, Emily Dunn, Amy Evers, Teri Hutchison, Mary Kuranda, Joshua Lampinen, Patricia Panek, La Son, Diggs Sledge, George Thomson Graphics, Joe Amft, Maria Duda, Fred Furtner, Carolyn Hall, Maria Kowalkowski, Proofreading Carol, Joy Farrell, Daniel James, Judith Literskis, Teresa Omiotek, James Madara, Bernard Hengesbaugh, Dan Blazer, North Carolina, David Braff, La Jolla, Naomi California, Stephen Breslau, Washington Dager, Atlanta Druss, Susan Georgia, New Essock, New York, Ellen York, John Hardy, James Harris, Maryland Shitij Kapur, Kenneth Kendler, Virginia Ronald, C Kessler, Kathleen Merikangas, Maryland Samples O'malley, Michael Owen, Fmed Sci, Judith Rapoport, Maryland Charles, F Reynolds, Myrna Weissman, Naomi Wray, Charles Zorumski, St Louis, Roy Grinker Sr, Daniel Freedman, Janck Barchas, Joseph Coyle, Jennifer Urbano Blackford, Dost Öngür, Ira Phillips, Helena Chmura Kraemer, Howard Bauchner, Stephan Heckers
Journal: JAMA Psychiatry (2015)
QUESTIONS OF IMPORTANCE TO THE MEMBERS ANSWERED.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Continuing Education Opportunities for Physicians
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Warning.
Authors: H. S. Anders
Journal: JAMA (1901)

Philadelphia, Oct. 12, 1901. <h3>To the Editor:</h3> —I desire to warn the profession against the operations of the Merchants' and Physicians' Adjusting Agency, of 346 Broadway, N. Y. Their scheme is to agree by written contract to collect bills for two years for $25, half of the first $50 collected. The doctor must bind himself to send every 20 days for five times, twice as many stamps as the number of debtors to whom letters will be sent. The point here is that if the physician should forget to send the stamps within the time mentioned, such is the wording of the contract, that he must forfeit $25 and risk hearing nothing more about his accounts. Should he refuse to pay, they threaten and demand a promissory note as the only concession. The nefarious trick is quite obvious.
Incorrect Word.
Journal: JAMA (1996)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Agranulocytosis caused by Chinese herbal medicines. Dangers of medications containing aminopyrine and phenylbutazone
Authors: C. A. Ries
Journal: JAMA (1975)

Four non-Chinese patients, middle-aged or older, developed agranulocytosis while taking Chinese herbal medicines for relief of arthritis and back pain. All four developed life-threatening infections with bacterial sepsis; one died. The herbal medicines were shown to contain substantial amounts of undeclared aminopyrine and phenylbutazone, drugs that are well-known causes of agranulocytosis. These Chinese herbal medicines are widely available over the counter throughout the United States. (<i>JAMA</i>231:352-355, 1975)
FATE OF INSULIN IN THE NORMAL AND DIABETIC ORGANISM
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Vertebral Manipulation
Authors: D. A. H. Yates
Journal: Annals of the Rheumatic Diseases (1973)

Logan describes the skin as a reflector of immunological changes.The chapter is divided into four parts-cutaneous manifestations of the rheumatic diseases, immunological aspects of skin diseases, inflammatory vaculitis, and cutaneous infections as a result of immune paresis.I found this to be the most interesting chapter.A few examples may be chosen.Antibodies to ultraviolet-irradiated DNA in SLE are discussed and their possible relevance to photosensitivity clearly emerges.Antibodies to the intercellular spaces of the epidermis have been found in pemphigus and to epithelial basement membranes in pemphigoid.The evidence for necrotizing vasculitis, polyarteritis nodosa, and Henoch-Schonlein purpura being due either to immune complex deposition or to antibodies directed at vascular tissues is reviewed.The book is profusely illustrated but, in that it deals with essentially visual phenomena, it is a great pity that the pictures are not in colour.A full list of references is provided at the end of each chapter.This volume draws together a mass of useful information which otherwise is not readily available.It presents the current position in our understanding of these complications and indicates the areas of uncertainty and the likely directions for profitable research.It is strongly recommended.