tbuckley/cabot-search huggingface dataset:
Cardiac Amyloidosis
Authors: ROBERT S. ELIOT, HUGH J. MCGEE, S. GILBERT BLOUNT
Journal: Circulation (1961)

AMYLOIDOSIS was first described byWilks in "The Guys Hospital Report" of 1856.1 It was referred to at that time as "lardaceous disease," obviously because of the physical similarity of amyloid to lard.Very few cases were reported until 1908 when Beneke and Bonning2 reported their experience.In 1929 Lubarsch3 reported three cases and suggested the criteria for diagnosis, but by 1930 only 10 cases were in the litera- ture.1-7Very little appeared in the English or American writings until the mid 1930's.By 1950 Higgins and Higgins8 had collected 71 cases from the literature and added their own experience.. Since their report, many other cases have been added and the concept of its rarity has faded in the light of these recent reports.The question of etiology re- mains to be answered, as well as the problem of terminology and classification.The lack of clarity in both these areas is demonstrated by the following terminology :9-23 atypical amyloidosis, paramyloidosis, unusual amyloid deposits, idiopathic amyloid disease, primary amyloidosis, and tumor-forming ainyloid.This problem in terminology has made it difficult to review with accuracy the literature on this subject.Perhaps the most workable classification is that suggested by Reimann, Koucky and Eklund:22 (1) primary amyloidosis-in which
Clinical, echocardiographic, and hemodynamic evidence of cardiac tamponade caused by large pleural effusions.
Authors: L M Kaplan, S K Epstein, S L Schwartz, Q L Cao, N G Pandian
Journal: American Journal of Respiratory and Critical Care Medicine (1995)

Large pleural effusions are typically associated with dyspnea and potential respiratory compromise. Experimental evidence suggests that with large effusions, increased intrapleural pressure may be transmitted to the pericardial space, resulting in impaired cardiac filling and reduced stroke volume. We report two cases in which large pleural collections were complicated by hypotension. The effusions were due to an infected right hepatic hydrothorax (Case 1) and a left malignant effusion (Case 2). Echocardiography demonstrated right and left ventricular diastolic collapse, respectively, confirming a diagnosis of cardiac tamponade. Large volume thoracentesis resulted in immediate hemodynamic improvement as demonstrated by a reduction in right ventricular and atrial pressures (Case 1) and echocardiographic resolution of left ventricular diastolic collapse (Case 2). These cases establish that large pleural effusions can cause hemodynamically significant cardiac tamponade. In addition, they illustrate how the demonstration of cardiac compressive physiology can significantly alter the therapeutic approach to large pleural effusions.
Issue Information ‐ TOC
Journal: Allergy (2019)

About the coverLa n proverb -"Si vis pacem, para bellum" that one can translate to "If you want peace, prepare for war" perfectly pictures the intense ba le that the innate immune system takes on every day.Athena, Greek goddess of wisdom and war, represents the wisdom of the innate immune system that strategically defends against the incoming threat.Poseidon, god of the seas, is the fi rst line of defense and furiously a acks foreign invaders.The innate immune system, like the shedding skin of the snakes on Medusa's head, is constantly being replenished and rejuvenated.In this issue, Maeda et al., in their comprehensive review, summarize recent advances in the involvement of pa ern recogni on receptors in allergic diseases.Luo et al. demonstrate a novel func on of langerin, a surface marker specifi c for Langerhans cells.Wang et al. explore the eff ect of benzo(a)pyrene co-exposure with Dermatophagoides Group 1 allergen on aryl hydrocarbon receptor signaling.Hashimoto et al., in their study on ordinary scabies, demonstrate that IL-31 (a pruritogenic cytokine) is generated largely by M2 macrophages and induced by thymic stromal lymphopoie n and perios n.Ro et al. inves gate the role of leukotriene B4 receptors in a neutrophil-dominant airway infl amma on.Kageyama et al. present results that indicate an involvement of basophils in the development of alpha-gal syndrome.
Council on Pharmacy and Chemistry
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Unilateral vocal cord paralysis
Authors: K. Calhoun
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Successful, normal childbirth after kidney homotransplantation
Authors: J. J. Kaufman
Journal: JAMA (1967)

IN APRIL, 1966 the first normal delivery at term after a kidney homotransplantation occurred at the Medical College of Virginia.<sup>1</sup>On Sept 19, 1966, the second such event in this country occurred at the University of California, Los Angeles, Center for the Health Sciences. The similarity between the two cases is noteworthy. Both women had received a kidney homograft from a living relative a little more than a year earlier. Both patients maintained excellent renal function throughout pregnancy; both had normal vaginal deliveries at term, and in each case the newborn child appears to be entirely normal, despite maintenance of immunosuppressive therapy during pregnancy. <h3>Report of a Case</h3> A 35-year-old married woman (023-10-30) was admitted to the UCLA Hospital on June 18, 1965, for a possible kidney homotransplantation. In April 1964 her blood urea nitrogen was 60 mg/100 cc, and she required several transfusions for anemia. A diagnosis of
Progress in Research in Emphysema and Chronic Bronchitis 1: Normal and Abnormal Pulmonary Circulation. Fifth Annual Conference on Research in Emphysema, Aspen, Colorado, June 13-16, 1962.
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Vaccination Coverage Among Adolescents Aged 13-17 Years—United States, 2007
Journal: JAMA (2009)

Three new vaccines have been recommended for adolescents by the Advisory Committee for Immunization Practices (ACIP) since 2005: meningococcal conjugate vaccine (MCV4; 1 dose), tetanus, diphtheria, acellular pertussis vaccine (Tdap; 1 dose), and quadrivalent human papillomavirus vaccine (HPV4; 3 doses). ACIP also recommends that adolescents should receive recommended vaccinations that were missed during childhood. Since 2006, CDC has conducted the National Immunization Survey-Teen (NIS-Teen) to estimate vaccination coverage from a national sample of adolescents aged 13-17 years. This report describes the findings from NIS-Teen 2007, which indicated substantial increases in receipt of new adolescent vaccinations compared with 2006, including Tdap (from 10.8% to 30.4%) and MCV4 (from 11.7% to 32.4%), and increases in coverage with childhood vaccinations, including measles, mumps, and rubella (MMR), hepatitis B (HepB), and varicella (VAR) (among those without disease history). An assessment of HPV4 coverage, which is reported for the first time, showed that 25.1% of adolescent females initiated the vaccine series (>/=1 dose) in 2007. To improve vaccination coverage among adolescents, health-care providers should take advantage of every health-care visit as an opportunity to evaluate vaccination status and administer vaccines when needed.
Cystic fibrosis
Authors: Beryl J Rosenstein, Pamela L Zeitlin
Journal: The Lancet (1998)

Cystic fibrosis (CF), the most common life-shortening autosomal recessive disorder in populations of European origin, is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene on chromosome 7. 1 Tsui LC The cystic fibrosis transmembrane conductance regulator gene. Am J Respir Crit Care Med. 1995; 151: S47-S53 Crossref PubMed Google Scholar The CFTR gene encodes a protein of 1480 aminoacid residues that functions as a cAMP-regulated chloride channel in the apical membrane of epithelial cells. Cloning of the gene in 1989 2 Kerem B Rommens JM Buchanan JA et al. Identification of the cystic fibrosis gene: genetic analysis. Science. 1989; 245: 1073-1080 Crossref PubMed Scopus (3248) Google Scholar significantly advanced our understanding of CF cell biology and pathophysiology, permitting more precise genetic testing and novel treatment approaches.
Scarlatinal Infectiousness.
Authors: Heman Spalding
Journal: JAMA (1904)

Chicago, July 18, 1904. <h3>To the Editor:</h3> —Will you kindly allow me to make a few comments on the editorial inThe Journal, July 16, entitled "Scarlatinal Infectiousness"? Lauder's two faulty "systems" of handling scarlet fever and the experience of Killick Millard are used as the basis of the editorial. I say faulty "systems" because they both have to their credit "return cases." The conclusions to be drawn from the editorial are, first, that mild cases of scarlet fever should be protected from severe and complicated cases; second, that in the absence of complications such as inflammation of mucous membrane and abscesses, a child can be turned loose with safety to others though the skin is still peeling; third, that the infectiousness of the desquamating skin is exaggerated. The editorial is interesting as a matter of current news, but decidedly harmful if accepted as a piece of authoritative advice as
THE ANTISCORBUTIC PROPERTY OF FOODS
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
F.R.C.P. London
Authors: D.-F Gibberd, J Hellier, J Sarsfield, N Watson, D Oakley, J Brenton, J Hunter, F Pilcher, N Skidmore, H Cohen, A Valman, -P Sims, -B Csr, S Higgs, D Nundy, Mr Irving, J Brooke, Linda Tze, Ching Ho, Barbara Lees, D Cooper, Estrange Southampton, G Stevenson, J O'brien, David Siggers, Ronald Tunbridge, P Banks, S Walpole, Cam- Brioge Mr, York- Shire Blackburne, B Branch, -D Macartheur, I -Catherine, G Ahuchogu, M Ainsworth, Barbara Al-Naddawi, S Armstrong, Kathleen Arora, M Badcock, R Bamford, M Blackburn, A Bone, J Bosley, S Brooks, Chea Brown, H Chang, Janet Chilton, G Clements, Hilary Clugston, Patricia Coysh, A Crisp, Geraldine Davies, B Davies, F Desai
Journal: BMJ (1974)
[unk] (Levothyroxine)
Authors: Tsung O. Cheng
Journal: JAMA (1992)

<h3>To the Editor.</h3> —What a pleasant surprise it was for me to read in the contents page of the May 22/29 issue of<i>JAMA</i>titles of various articles in their local languages. But I wonder why the title in Chinese: "Bone Mineral Density in Premenopausal Women Receiving Long-term Physiological Doses of Levothyroxine," by Kung and Pun from Hong Kong, contained the English word levothyroxine untranslated. There is a Chinese word for levothyroxine: [unk] We can reach the common goal sooner if we share information and resources together.<sup>1</sup><i>JAMA</i>has made another giant step in the right direction.
Reply
Authors: Kai Markus Schneider, Veerle Bieghs, Oliver Pabst, Christian Trautwein
Journal: Hepatology (2015)

Potential conflict of interest: Nothing to report. Author names in bold designate shared co‐first authorship. We thank Dr. Ling and his colleagues for their comments on our recent publication. Classification of intestinal mononuclear phagocytes (MNPs) caused some confusion in the past. In particular, most Cx3cr1‐expressing cells that had been considered as dendritic cells (DCs), for example, in the landmark article by Niess et al.1 and in the letter of Dr. Ling, are now commonly regarded as macrophages.1 To analyze the effect of high‐fat diet (HFD) on MNPs, we differentiated between various lamina propria MNP populations, including both DCs and iMΦ based on surface marker expression.3 To study DC subsets, we analyzed the frequency of CD11b+CD11c+MHCII+CD103+ and CD11b–CD11c+ MHCII+CD103+ cells. Both subsets appeared unchanged comparing wild‐type (WT) and Cx3cr1–/– mice. In contrast, we observed a significantly lower abundance of CD11b+CD11c+MHCII+F4/80+ cells in Cx3cr1–/– mice compared to WT mice, a subset of cells that corresponds to CD64+CX3CR1high iMΦ. Consequently, our data suggested that Cx3cr1 deficiency mainly affects iMΦ. Whereas DCs are critical for induction of adaptive immune responses, F4/80+ iMΦ show highest phagocytic capacity of all lamina propria cells and are important for local clearance of bacterial products in the lamina propria.2 Indeed, a reduction of this specific immune cell subset in our study was associated with decreased phagocytic capacity of colonic lamina propria cells. Concomitantly, we measured higher concentrations of endotoxin in portal serum of Cx3cr1–/– mice upon HFD feeding. Accordingly, antibiotic treatment led to a marked improvement of all hepatic hallmarks of nonalcoholic steatohepatitis in Cx3cr1–/– mice, indicating that the pronounced activation of hepatic innate immune response is dependent on the translocation of bacterial products and intestinal barrier dysfunction in Cx3cr1–/– mice. Absence of Cx3cr1 was associated with decreased expression of epithelial tight junctions, a reduced abundance of intestinal macrophages, and increased bacterial translocation. Mechanistically, we observed that depletion of the intestinal microbiota did not only reduce the number of infiltrating macrophages in the liver, but also induced up‐regulation of the restorative markers, CD206 and CD124, on these cells. Therefore, our study suggests that CX3CR1 limits progression of steatohepatitis by maintaining intestinal homeostasis. Future studies are required to investigate the effect of HFD on intestinal adaptive immune response in order to elucidate the role of antigen presentation and mucosal tolerance in maintaining intestinal barrier integrity. A selective depletion of different subsets of MNPs could be an elegant experimental approach to decipher their specific functions for intestinal immune homeostasis. We appreciate this idea; however, we think these experiments are beyond the scope of this study.
Green Trees for Greenhouse Gases: A Fair Trade-Off?
Authors: Charles W. Schmidt
Journal: Environmental Health Perspectives (2001)

While forests retain carbon in plants, detritus, and soils, utility companies spew it into the air as carbon dioxide, the main greenhouse gas behind global warming. Industrial carbon dioxide emissions aren't currently regulated by federal law, but a number of companies are trying to address the problem voluntarily by launching carbon sequestration programs in heavily forested countries, where carbon is contained in so-called sinks. But the November 2000 meeting of the Kyoto Protocol delegates in The Hague collapsed over the issue of the acceptability of carbon sinks as a source of carbon pollution credits, delivering what many see as a deathblow to the concept. At issue are a host of ecological and statistical questions, differing local land use practices, cultural factors, issues of verifiability, and even disagreement over definitions of basic terms such as "forest" Kyoto negotiators are gearing up for another round of discussions in Bonn in May 2001, and it is likely that the continuing debate over carbon sinks will dominate the agenda.
Health Policy
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Exercise Tests
Authors: Henry Blackburn
Journal: JAMA (1972)

<h3>To the Editor.—</h3> This is in reply to Hershberg's LETTER concerning our report on procedure, safety, and litigation experience in exercise tests. We attempted to present in straightforward, descriptive, and quantitative terms the results of a questionnaire survey. We resisted as much as possible interpretation and conclusions from the data. Hershberg stated categorically that "... only ten of the 16 reported deaths were in any way a result of the tests." We regret that we had not the advantage of divination, which would have spared us the trouble of a detailed review of the reported deaths. Hershberg said also that "most [of the exercise test subjects] had suffered recent pain in the chest or similar complaints. The mean age of these individuals was probably 50 years (or possibly older)." We did not obtain this information in our questionnaire or report it in our article, and preferred not to speculate. Hershberg stated
Intracerebral hemorrhage in a patient with eclampsia
Authors: D. W. Beck
Journal: JAMA (1981)

THE INCIDENCE of intracerebral hemorrhage accompanying nonfatal eclampsia is unknown, but this lesion is found in 10% to 60% of all deaths due to eclampsia.<sup>1,2</sup>With the advent of the noninvasive, high-resolution, imaging technique of computed cranial tomography (CT), the early diagnosis of intracerebral hemorrhage in a patient with eclampsia can be achieved. Periventricular subependymal hemorrhage is a rare phenomenon but has been found at autopsy in cases of eclampsia in which disseminated intravascular coagulation (DIC) or hyperemesis gravidarum had been associated.<sup>2,3</sup>We report a case of periventricular hemorrhage in a patient with eclampsia in whom the CT scan allowed precise diagnosis and rationale for management. A close correlation between the clinical course and serial CT changes was noted. <h3>Report of a Case</h3> A 26-year-old woman, gravida 2, para 1, abortus 1, in the last trimester of pregnancy was referred to the University of Iowa Hospitals, Iowa City,