tbuckley/cabot-search huggingface dataset:
Epidemiologic Relation between HIV and Invasive Pneumococcal Disease in San Francisco County, California
Authors: Mark S. Dworkin, Debra L. Hanson
Journal: Annals of Internal Medicine (2000)

Letters20 June 2000Epidemiologic Relation between HIV and Invasive Pneumococcal Disease in San Francisco County, CaliforniaMark S. Dworkin, MD, MPHTM and Debra L. Hanson, MSMark S. Dworkin, MD, MPHTMCenters for Disease Control and Prevention; Atlanta GA, 30333 (Dworkin)Centers for Disease Control and Prevention; Atlanta GA, 30333 (Hanson) and Debra L. Hanson, MSCenters for Disease Control and Prevention; Atlanta GA, 30333 (Dworkin)Centers for Disease Control and Prevention; Atlanta GA, 30333 (Hanson)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-12-200006200-00033 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Nuorti and colleagues (1) reported important information about the epidemiology of invasive pneumococcal disease from population-based laboratory data collected in San Francisco County, California, from October 1994 to June 1997. They described a statistically significant decreasing trend in the incidence of pneumococcal disease in persons with AIDS, with the most substantial decrease occurring from 1996 to 1997. For comparison, we analyzed data from the Adult and Adolescent Spectrum of HIV Disease (ASD) Project of person-time from January 1994 through December 1998; these data were collected from more than 100 inpatient and outpatient facilities in 10 U.S. cities ...References1. Nuorti JK, Butler JC, Gelling L, Kool JL, Reingold AL, Vugia DJ. Epidemiologic relation between HIV and invasive pneumococcal disease in San Francisco County, California. Ann Intern Med. 2000;132:182-90. LinkGoogle Scholar2. Dworkin MS, Wan PC, Hanson DL, Jones JL. Progressive multifocal leukoencephalopathy: improved survival of human immunodeficiency virus–infected patients in the protease inhibitor era. J Infect Dis. 1999;180:621-5. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Centers for Disease Control and Prevention; Atlanta GA, 30333 (Dworkin)Centers for Disease Control and Prevention; Atlanta GA, 30333 (Hanson) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEpidemiologic Relation between HIV and Invasive Pneumococcal Disease in San Francisco County, California J. Pekka Nuorti , Jay C. Butler , Lisa Gelling , Jacob L. Kool , Arthur L. Reingold , and Duc J. Vugia Epidemiologic Relation between HIV and Invasive Pneumococcal Disease in San Francisco County, California Immaculada Grau , Josefina Liñares , and Roman Pallares Metrics Cited byImmunizations, Vaccine-Preventable Diseases, and HIV Infection 20 June 2000Volume 132, Issue 12Page: 1009KeywordsAIDSAdolescentsAtrial septal defectHIVHIV epidemiologyHighly active antiretroviral therapyOutpatientsPolysaccharidesResearch laboratoriesVaccines Issue Published: 20 June 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Diabetes, New York
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Most US troops may leave Somalia by May; military medicine still likely to have role
Authors: P. Gunby
Journal: JAMA (1993)

OPERATION RESTORE HOPE in Somalia may become a United Nations—centered peacekeeping effort within the next 8 weeks. But US military medicine probably will remain involved, because the planned 25000-member United Nations force is expected to include about 4000 military personnel from this country. Those 4000 contrast with the 24883 US military members who were serving in Somalia at the beginning of last month. There has been concern on the part of US military medical people and others in recent days because of an increase in violence, some directed against Americans and members of other nations' military units, on the part of warring factions and those intent on robbery. In addition to potential violence, there is the risk of death or injury from unrelated accidents. And the hot-weather season also is about to begin. Temperatures in Mogadishu, for example, increase in April to a mean daily maximum of 32°C (90°F) and
ONE EDITORIAL YEAR
Authors: J. H. T.
Journal: JAMA (1960)

Calendar year, fiscal year, and academic year —all identify specific chronological periods. "Editorial year" is a less familiar designation. In the reference of this communication, the editorial year began October 26, 1959, with my assumption of responsibilities as Director of the Division of Scientific Publications of The American Medical Association. The editorship of the J. A. M. A., one of the largest professional journals in America, and the supervision of the ten specialty journals published by the A. M. A. were paramount among the several Division activities. Under the leadership of the Executive Vice-President, Dr. F. J. L. Blasingame, these allocations of function followed reorganization of the staff at 535 North Dearborn Street, authorized by the Board of Trustees in August, 1958. The honeymoon for the Director of the Division of Scientific Publications, in keeping with contemporary nuptial honeymoons, was short. The satisfaction in the assignment, however, not only persists
Surgical Miscellanies
Authors: J. Cleland
Journal: BMJ (1868)

ON April 5th, I was asked to see a case of strangulated hernia.The patient was a robust man of middle agc; the hernia was scrotal, of about the size of a hen's egg, and seemingly direct; but it is proper to state that a truss had been worn on account of it for some years.The taxis made no impression on the size of the swelling, which was firm, and gave a dull sound on percussion; and, as symptoms of strangulation had existed for more than twelve hours, and vomiting had now set in, andI
Anniversary
Authors: Jeffrey Johnson
Journal: JAMA (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prolonged Intubation and Subglottic Stenosis
Authors: B. Hardcastle
Journal: BMJ (1967)

MMBICLJOURNALAddiction to Diazepam (Valium) SIR,-Prominence has recently been given to the phenomenon of addiction to so-called innocuous drugs.'The following is a case report of addiction to such a drug-namely, diazepam, a preparation which is being used widely in general practice and in psychiatry.
Germ cell cancer and multiple relapses: Toxicity and survival.
Authors: Jakob Lauritsen, Maria Gry Gundgaard Kier, Mette Sakso Mortensen, Mikkel Bandak, Ramneek Gupta, Niels Vilstrup Holm, Mads Agerbaek, Gedske Daugaard
Journal: Journal of Clinical Oncology (2015)

4533 Background: A small fraction of patients with germ-cell cancer (GCC) receive more than one line of systemic treatment. The purpose of this study was to evaluate late-toxicity and survival in an unselected cohort of patients who relapsed after initial systemic treatment for disseminated disease. Methods: Based on the Danish DaTeCa database we identified all patients who received two or more lines of systemic treatment. Information on late-effects and mortality in GCC-survivors was obtained through linkage to national registers. Prognostic factors for relapse and death were identified and compared to the International Prognostic Factors Study Group (IPFSG). Results: In total, 268 patients received two or more lines of systemic treatment for disseminated GCC. Approximately half of the patients died of their disease (n = 136). The surviving patients (n = 132) had highly increased risk of death of other causes hazard ratio (HR): 2.5 (95% CI: 1.6-4.1), second cancer HR: 3.4 (2.0-5.7), major cardiovascular disease HR: 1.9 (1.0-3.3), pulmonary disease HR: 2.4 (1.3-4.4), gastrointestinal disease HR: 7.1 (3.5-14.3), renal impairment HR: 9.2 (3.4-25.5), and neurological disorders HR: 5.4 (2.7-10.8) compared to patients treated with orchiectomy only. We found a dose-response relationship with increasing number of treatment lines within most toxicities. The IPFSG-classification was confirmed in our population; however, we could not confirm primary site and hCG as independent factors. We identified increasing age as a possible new prognostic factor for treatment failure, hazard ratio (HR): 1.2 (1.2-1.5) per 10 years. Conclusions: GCC-survivors after second-line systemic treatment have a highly increased risk of severe late-toxicity and death, and should be candidates for life-long follow-up. The IPFSG-classification was confirmed in this unselected population.
Phase III, randomized, double-blind study of elesclomol and paclitaxel versus paclitaxel alone in stage IV metastatic melanoma (MM)
Authors: A. Hauschild, A. M. Eggermont, E. Jacobson, S. J. O'Day
Journal: Journal of Clinical Oncology (2009)

LBA9012 Background: Elesclomol is an investigational first-in-class oxidative stress inducer that increases oxidative stress in cancer cells leading to mitochondria-induced apoptosis. Methods: Patients (pts) with Stage IV MM, no prior chemotherapy, LDH μ 2× ULN were randomized (1:1) to either 213 mg/m 2 elesclomol in combination with 80 mg/m 2 paclitaxel (ELPAC) or 80 mg/m 2 paclitaxel alone (P); both were given weekly ×3 followed by 1 week rest until disease progression. Pts were stratified by prior non-cytotoxic treatment, M1 grade, and LDH. The primary endpoint was PFS with &gt;90% power to detect a 2-month improvement. The primary PFS analysis was planned once all pts had been enrolled and at least 164 PFS events had occurred. Results: 651 pts were enrolled between September 2007 and February 2009. Prognostic factors were generally well balanced. PFS analysis was based on investigator assessment of 411 pts (219 events). Median PFS was 3.5 m (95% CI 2.7–3.7) in ELPAC and 1.9 m (95% CI 1.9–3.3) in P [HR 0.88; 95% CI 0.67–1.16, p=0.3695]. The median number of cycles was 3 in ELPAC and 2 in P. Safety analysis showed increased signals on ELPAC including increased ≥Gr 3 AEs (N=405, 32.8% vs. 23.5%), increased AEs leading to death (N=405, 3.5% vs &lt;1%) and increased overall deaths (N=651, 80 vs 53; 80% censored). Most common AEs in ELPAC were fatigue (32.8%), alopecia (31.3%) and nausea (27.9%). Conclusions: There was an improvement in PFS in the ELPAC arm, but it did not achieve statistical significance. In February 2009, the study was halted based on the recommendation of the DMC to unblind the study after the DMC observed increased deaths on the ELPAC arm. The DMC could not determine whether the observed increased deaths were treatment related or not. Of note, in this analysis there were no specific target organ toxicities attributable to ELPAC that could explain the imbalance of deaths. OS data continues to be collected to determine if the observed imbalance in OS persists as the data mature. [Table: see text]
TRANSFUSION OF DUODENAL CONTENT
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DOMESTIC CORRESPONDENCE.
Authors: Joseph Jones
Journal: JAMA (1892)

<h3>History of Asiatic Cholera in New Orleans, La.</h3><h3>To the Editor of the Journal of the American Medical Association:</h3> The rapid progress of Asiatic cholera in Europe at this time, has justly alarmed the sanitary authorities of this great republic; but health authorities should not lose sight of the important fact that the<i>ordinary bowel affections at all times present with us inflict in the long run far greater mortality than Asiatic cholera</i>. This proposition will be illustrated by the following <h3>BRIEF HISTORY OF ASIATIC CHOLERA IN NEW ORLEANS.</h3> It would be foreign to our purpose to enter fully into the history of this foreign pestilence which has at various times reached the shores of Louisiana from the shores of Europe across the waters of the Atlantic ocean and the Gulf of Mexico. Asiatic cholera has played no insignificant part in the grand carnival of disease and death. In 1832, Asiatic cholera in conjunction with yellow
Euthanasia and Law in Europe
Authors: Alan G. Williams
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CORRELATION BETWEEN CIRCULATING ANGIOGENIC CELL MOBILIZATIONS AND RECOVERY OF CORONARY FLOW RESERVE IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION
Authors: Han Saem Jeong, Soon Jun Hong, Jae Hyoung Park, Jong-Ho Kim, Seung Cheol Choi, Chul-Min Ahn, Je Sang Kim, Do-Sun Lim
Journal: Journal of the American College of Cardiology (2012)
A new “gold standard” for assessment of prognosis (prog) understanding among advanced cancer patients (acp): Narrative interviews of patients in phase I trials and invested third party observers (itpo)
Authors: C. K. Daugherty, N. Stein, T. Trabasso, F. J. Hlubocky
Journal: Journal of Clinical Oncology (2004)

8134 Background: Despite terminal illness, prior research shows acp: overestimate survival, provide little acknowledgement (ack) of prog, and have curative care goals. Yet, this research may not accurately reflect prog awareness as it has not accounted for how fear, anxiety, and hope effect measured responses to queries about when (or if) acp believe they will die. This research has also not included valuable observational experiences of those who bear witness to acp illness experiences. Methods: Narrative analysis explains effects of emotion on cognitive understanding by seeking descriptions of prior experiences and assessing goal appraisal processes. We studied its use on qualitative interviews of acp and their itpo (spouses/significant others). Results: To date, 28 terminally ill, acp receiving experimental (phase I trial) chemotherapy and 28 itpo have been separately interviewed: 50% male; median age 57 (23–78); 90% married; 96% Caucasian; 57% >high school education; expected median prog: 8 months. Quantitative interview data include, 1.) Likert scores (1–10) of likelihood of chemotherapy in: "halting" cancer (mean 7.0, with higher scores among women acp), producing "remission" (mean 6.4), and (among 30% stating it possible) "curing" (mean 7.1); and, 2.) Scales of affective balance and positive ways of thinking with: itpo with more depressed mood (p<.008), and acp with greater changes in thinking about the value of their life (p<0.1). Narrative analysis reveals that within virtually all acp-itpo interview pairs, there was an ack of a terminal prog—although many did not describe physician disclosure of prog and many acks came outside specific queries about prog understanding. Conclusions: While—in response to structured queries—acp state both significant expectations of benefit from chemotherapy and inaccurate estimates of survival, narrative analyses of acp and itpo descriptions of illness experiences provide a more accurate portrayal of patient understanding of prog. No significant financial relationships to disclose.
ASEPSIS BEFORE BATTLE.
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Some Radiologists Want More Money Up Front
Authors: M. Mitka
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Selected Phenolic Compounds in Cultivated Plants: Ecologic Functions, Health Implications, and Modulation by Pesticides
Authors: Otto Daniel, Matthias Samuel Meier, Josef Schlatter, Peter Frischknecht
Journal: Environmental Health Perspectives (1999)

Phenolic compounds are widely distributed in the plant kingdom.Plant tissues may contain up to several grams per kilogram.External stimuli such as microbial infections, ultraviolet radiation, and chemical stressors induce their synthesis.The phenolic compounds resveratrol, flavonoids, and furanocoumarins have many ecologic functions and affect human health.Ecologic functions include defense against microbial pathogens and herbivorous animals.Phenolic compounds may have both beneficial and toxic effects on human health.Effects on lowdensity lipoproteins and aggregation of platelets are beneficial because they reduce the risk of coronary heart disease.Mutagenic, cancerogenic, and phototoxic effects are risk factors of human health.The synthesis of phenolic compounds in plants can be modulated by the application of herbicides and, to a lesser extent, insecticides and fungicides.The effects on ecosystem functioning and human health are complex and cannot be predicted with great certainty.The consequences of the combined natural and pesticide-induced modulating effects for ecologic functions and human health should be further evaluated.