tbuckley/cabot-search huggingface dataset:
Secondary and tertiary rediversion of the urinary tract. A study based upon 72 cases among 840 pelvic exenterations for advanced cancer
Authors: A. Brunschwig
Journal: JAMA (1968)

Among 840 patients who received pelvic exenterations which entail total diversion of the urinary tract, a second or even third urinary tract rediversion was deemed necessary to preserve life-sustaining urinary tract function in 72. In those who lived more than five years after pelvic exenteration for advanced cancer, the most frequent cause of death was uremia or urinary tract sepsis. Once urinary diversion is done, constant surveillance is obligatory for evidence of progressing urinary tract deterioration. Rediversion is indicated under certain conditions as a life-saving measure in spite of its substantial risks. The variables in each case preclude the elaboration of hard and fast rules and the patient's management must be highly individualized. Among 58 patients in whom rediversion was done five or more years ago, 24 survived at least five years. Among 14 patients so operated upon within the past five years, three are living. All of the patients originally had advanced cancer.
Abstract 15926: Impact of Small Body Surface Area on Para-valvular Leak After Balloon-expandable Transcatheter Aortic Valve Replacement
Authors: Yoshio Maeno, Nobuyuki Takahashi, Yigal Abramowitz, Yoshio Kazuno, Hiroyuki Kawamori, Mohammad Kashif, Tarun Chakravarty, Mamoo Nakamura, Wen Cheng, Hasanian Jilaihawi, Rajendra Makkar
Journal: Circulation (2015)

Aims: The efficacy and safety of balloon-expandable transcatheter aortic valve replacement (TAVR) in patients of small body surface is not well understood. The aim of this study was to evaluate that the efficacy and safety and association between small BSA (S-BSA) and para-valvular leak (PVL) after balloon-expandable TAVR. Methods: Between January 2013 and April 2015, a total of consecutive 379 patients with severe aortic stenosis underwent balloon-expandable TAVR (SAPIEN =82 or XT =297) and had suitable contrast cardiac CT. Patients with S-BSA were defined as &lt;1.75cm2. The S-BSA group included 149 patients and the remaining 230 patients were included in the large BSA (L-BSA) group. Major adverse cerebro-cardiac vascular events (MACCE) at 30-days were recorded. Post procedural PVL and mean pressure gradient were also evaluated by transthoracic echocardiography at 30-days. Results: Mean aortic annulus area in the S-BSA group was significantly smaller than in the L-BSA group (412.7 ± 70.8 cm2 vs. 498.5 ± 88.8 cm2; p&lt; 0.001) but degree of device oversizing was similar between groups (16.6% vs 17.0%, p=0.74). MACCE were similar between both groups (6.7% vs. 6.1%; p =0.483), however major vascular events were significant higher in S-BSA (15.4% vs. 7.0%; p=0.007). There was one patient with aortic annulus injury in the S-BSA group. Similar post-procedural mean pressure gradient was achieved in both groups (10.2 ± 4.1 mmHg vs. 9.6 ± 3.9 mmHg; p=0.17). S-BSA was significantly associated with the incidence of PVL (PVL ≤mild: 41.6% vs. 23.5%; p&lt;0.001; moderate PVL ≤; 12.1% vs. 5.0%; p=0.009). Post-dilatation was higher in S-BSA (14.8% vs. 7.4%; p=0.017). Multivariate analysis demonstrated that aortic valve calcium was an independent strong predictor of PVL (Odds ratio (OR): 1.002; 95% confidence interval (CI) 1.001-1.003; p=0.001). S-BSA was found to be independently protective for PVL (OR: 0.38; 95% CI 0.24-0.61; p&lt;0.001). Conclusions: TAVR in patients with S-BSA was associated with similar MACCE overall but with higher incidence of major vascular events compared to L-BSA. S-BSA was found to be independently protective for post procedural PVL at 30-days in patients that underwent balloon-expandable TAVR. This appeared independent to the degree of oversizing.
Abdominal Operations
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
GRADUATE MEDICAL STUDY ABROAD
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Authors' Reply
Authors: Sam Gandy, Suzana Petanceska
Journal: PLoS Medicine (2005)

Gatz's statement, "At least half of the explanation for individual differences in susceptibility to Alzheimer disease is genetic" [1], is, in my opinion, incorrect.As the one who led the team debating Ashford and Mortimer, whose 2002 article [2] supports this statement, at the 2001 conference on Alzheimer disease (AD) in Cincinnati ("Challenging Views of Alzheimer's Disease") [3], I think that the evidence that dietary and lifestyle factors explain the majority of the individual risk for AD in the US is very strong.My original paper in 1997 [4] found that total dietary fat and energy intake were the most important dietary risk factors, while fi sh and cereal intake were the most important risk reduction factors.These fi ndings have been generally confi rmed by Drs.Luchsinger and Morris and others.The reason I did my study was that the Honolulu Heart Study reported that Japanese American men in Hawaii had 2.5 times the risk of AD of native Japanese.African-Americans have about four times the risk of AD of native Nigerians.If genetics were the primary risk factor, those living in the US would have a risk of developing AD very similar to that of individuals living in their ancestral home.The reason this is not the case is that the American diet provides too much food, which is a particular problem for those genetically predisposed to AD.
Effect of Microwave Oven on Implanted Cardiac Pacemaker
Authors: Albert C. Hamburger
Journal: JAMA (1970)

<h3>To the Editor.—</h3> Although the effects of external radio-frequency radiation on implanted cardiac pacemakers have received much attention in the literature (Lichter I, Borrie J, Miller WM: Radio-frequency hazards with cardiac pacemakers.<i>Brit Med J</i><b>1</b>:1513, 1965; Carleton RA, Sessions RW, Graettinger JS: Environmental influence on implantable cardiac pacemakers.<i>JAMA</i><b>190</b>:938, 1964; Siddons H, Sowton E:<i>Cardiac Pacemakers</i>. Springfield, Ill, Charles C Thomas Publisher, 1967, pp 99-102), to our knowledge high-frequency stimuli from microwave ovens have not previously been reported to interfere with pacemaker function. We have recently observed such an interference. <h3>Report of a Case.—</h3> A 68-year-old white male physician developed complete A-V block during November 1969. The patient subsequently experienced dyspnea and pedal edema, but did not develop syncope. On Nov 24, 1969, a ventricular sensing pacemaker (Medtronic Corporation, Model #5841) was implanted through the left external jugular vein; the pulse generator was placed in a
De Arte Phisicali et de Cirurgia of Master John Arderne, Surgeon of Newark, Dated 1412.
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
FDA seeks swifter approval of drugs for some life-threatening or debilitating diseases
Authors: C. Marwick
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transfusion Fatalities
Authors: P. L. Deshmukh
Journal: BMJ (1937)

BACKGROUND--Manufacturers of ionisers claim many benefits from the use of their devices, including the relief of asthma. Particles removed from the air are likely to include airborne allergens, so ionisers may achieve an effect by reducing the allergen load. METHODS--The effect of ionisers on airborne concentrations of house dust mite allergen Der p I was investigated in a double blind, crossover, placebo controlled trial in the homes of 20 children with allergic asthma. Subjects recorded their peak expiratory flow rate (PEFR) twice daily and completed a daily symptom score and treatment schedule on a diary card for two six week periods, one with an active ioniser and the other with a placed ioniser (randomly allocated) used in the living room and the bedroom. RESULTS--Airborne Der p I concentrations fell significantly during the active period compared with the placebo period, but there was no significant change in PEFR, symptom scores, or treatment usage. There was an increase in night time cough which almost reached significance during the active period. CONCLUSIONS--This study indicates that the use of ionisers cannot be recommended in the homes of asthmatic subjects to improve their symptoms. The significant reduction of airborne allergen concentrations may be of use as part of a multidevice allergen avoidance regimen, but the increase in night time cough requires further study.
An End to the Medicare Fee Disparity
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review Challenges in Inflammatory Bowel Disease Second edition. Edited by Derek P. Jewell, Neil J. Mortensen, A. Hillary Steinhart, John H. Pemberton, and Bryan F. Warren. 400 pp., illustrated. Malden, MA, Blackwell, 2006. $129.95. 978-1-4051-2234-4 Inflammatory Bowel Disease and Familial Adenomatous Polyposis: Clinical Management and Patients' Quality of Life Edited by Gian Gaetano Delaini. 481 pp., illustrated. Milan, Springer-Verlag Italia, 2006. $259. 978-88-470-0433-7
Authors: G.N.J. Tytgat
Journal: New England Journal of Medicine (2007)
Ocular Pemphigus
Authors: Helen Ollendorff Curth
Journal: British Journal of Dermatology (1955)

Journal Article Ocular Pemphigus Get access Helen Ollendorff Curth, M.D. Helen Ollendorff Curth, M.D. New York Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 67, Issue 8-9, 1 August 1955, Page 324, https://doi.org/10.1111/j.1365-2133.1955.tb12747.x Published: 01 August 1955
Acute aortic thrombosis in antithrombin III deficiency
Authors: M. E. Shapiro
Journal: JAMA (1981)

Two cases of acute aortic thrombosis, a previously unreported complication of antithrombin III deficiency, are reported. Both patients had abnormally low antithrombin III levels, which improved to normal levels with warfarin sodium therapy. The possibility of antithrombin III deficiency should be considered in young patients with acute arterial thrombosis. (<i>JAMA</i>1981;245:1759-1761)
Correction
Journal: Circulation (2007)

which published with the Abstracts From the 47th Annual Conference on Cardiovascular Disease Epidemiology and Prevention in the February 27, 2007, issue of the journal (Circulation.2007;115:e254), an error was made.In subsequent re-analysis of the data while responding to referee comments, the authors found that the primary result presented in the abstract was incorrect because of the inadvertent use of observation periods of inappropriate length for some patients.This issue created a bias in favor of atorvastatin use.When corrected, the primary result no longer shows a statistically significant cardiovascular event rate reduction for atorvastatin beyond that seen with simvastatin.The authors regret this error.The secondary analysis end point, which is now included, serves 2 purposes: It is a correction of an erroneous result featured in the poster that was presented at the conference, and it highlights that the time frame of the analysis made a significant difference in the results.
E/Tablets to collect research-quality, patient-reported data
Authors: H. E. Uronis, J. E. Herndon, A. Coan, K. Bronson, J. Wheeler, H. K. Lyerly, M. A. Morse, A. P. Abernethy
Journal: Journal of Clinical Oncology (2008)

17528 Background: Programmed, wireless, notebook-and-pen style, computers (“e/Tablets”) can collect review of systems data at the point of care, for use in the clinic visit. Can e/Tablets deployed in outpatient oncology clinics be used to collect research survey data that are comparable to paper-based data? Methods: We used PACE e/Tablets (SOS, Inc.) to administer the disease-specific Functional Assessment of Cancer Therapy (FACT), MD Anderson Symptom Inventory (MDASI), and FACT-GOG-Neurotoxicity (NTX) scales. Participants were 113 gastrointestinal (GI) cancer patients in Duke GI Oncology Clinic. At each of 4 visits in 6 months, participants completed all surveys in electronic format and 1 survey on paper. Subscales (electronic vs. paper) were compared using paired t-tests. Patients completed an electronic satisfaction survey. Results: Mean age, 57 (SD 11); 67% male; 80% Caucasian; 47% no college degree; 67% metastatic cancer. Patients strongly supported e/Tablets: easy to read (97%), easy to respond to questions (97%), weight of computer comfortable (92%). Patients reported e/Tablets to be helpful for reporting symptoms (82%), and would recommend them to other patients (88%). After Bonferonni corrections (0.05/10=0.005), survey subscale scores for paper and electronic were similar except for the NTX scale. Conclusions: Patients are satisfied with e/Tablets to collect survey data. Preliminary results show that e/Tablets furnish comparable data to those collected by paper questionnaires on nearly all subscales tested. These results in GI cancers support our previous breast cancer study results, suggesting that e/Tablets offer a valid, feasible method for collecting research-quality, clinically relevant data from patients in outpatient academic oncology. Comparison of instrument subscales collected via paper or electronic methods N Paper Means (SD) Electronic Means (SD) P Fact-G Physical 92 20.8 (5.5) 21.3 (5.0) 0.055 Fact-G Social 87 23.6 (4.3) 22.6 (5.7) 0.021 Fact-G Emotional 93 18.6 (4.3) 19.1 (4.3) 0.024 Fact-G Functional 93 18.5 (5.6) 17.9 (5.6) 0.025 NTX 79 36.1 (6.8) 37.1 (5.5) 0.002 MDASI Symptom 82 1.8 (1.3) 1.9 (1.5) 0.232 MDASI Interference 82 2.3 (2.1) 2.4 (2.2) 0.437 Author Disclosure Employment or Leadership Consultant or Advisory Role Stock Ownership Honoraria Research Expert Testimony Other Remuneration Pfizer Pfizer Pfizer
Amikacin therapy for serious gram-negative infection
Authors: A. A. Pollock
Journal: JAMA (1977)

Amikacin sulfate was administered to 18 patients for the treatment of 19 severe infections. Seventeen infections were caused by gentamicin-resistant Gram-negative bacilli, and 13 patients were bacteremic. Bacteriologic cure was attained in all but one instance, and effective serum, bile, and pleural fluid drug levels were demonstrated. Drug-related fever occurred in one patient, and another experienced a maculopapular rash and monilial intertrigo. In three patients, reversible renal toxicity developed, but none had clinical evidence of ototoxicity. Amikacin sulfate in a dose of 15 mg/kg/day is an effective antibiotic for the treatment of serious Gram-negative infections, particularly those due to gentamicin-resistant organisms. (<i>JAMA</i>237:562-564, 1977)
DUODENAL DIVERTICULA
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Error in Conflict of Interest Disclosures
Journal: JAMA Network Open (2020)

Paulette D. Chandler, MD, MPH; Wendy Y. Chen, MD, MPH; Oluremi N. Ajala, MD, MPH; Aditi Hazra, PhD, MPH; Nancy Cook, ScD; Vadim Bubes, PhD; I-Min Lee, MBBS, ScD; Edward L. Giovannucci, MD, ScD; Walter Willett, MD, DrPH; Julie E. Buring, ScD; JoAnn E. Manson, MD, DrPH; VITAL Research Group