tbuckley/cabot-search huggingface dataset:
Estrogen Receptor beta Exerts Growth-Inhibitory Effects on Human Mammary Epithelial Cells.
Authors: A. Springwald, C. Lattrich, O. Ortmann, O. Treeck
Journal: Cancer Research (2009)

Abstract In mammary epithelium estrogen receptor beta (ERbeta) is widely expressed. Its expression is reported to decline during carcinogenesis of the breast and other tissues. In this study, we examined the consequences of a loss of ERbeta expression in mammary epithelial cells. We knocked down ERbeta transcript levels in human mammary epithelial MCF-10A cells and in MCF-7 breast cancer cells by means of stable transfection with a specific shRNA plasmid. ERbeta knockdown resulted in a significant growth increase of both cell types in a ligand-independent manner. This effect was accompanied by elevated cyclin A2 expression in MCF-10A cells and by decreased expression of growth-inhibitory p21/WAF and epithelial cell marker cytokeratine 8 in both cell lines. Transfection of ERbeta shRNA did not alter the absent proliferative estrogen response of MCF-10A cells, but conferred sensitivity to selective estrogen receptor modulator tamoxifen to this cell line. In contrast, ERbeta knockdown diminished estrogen responsiveness of MCF-7 breast cancer cells and also weakened the effect of tamoxifen on this cell line. These ligand-dependent effects only observed in MCF-7 cells exhibiting a high ERalpha/beta ratio were accompanied by smaller estrogenic repression of p21/WAF expression, an impaired tamoxifen-triggered induction of this gene and by relative downregulation of ERalpha and cyclin A2 transcript levels. Our data suggest that ERbeta exerts antiproliferative effects both on MCF-10A and MCF-7 cells in a ligand- and ERalpha-independent manner by regulation of p21/WAF or cyclin A2 gene expression. Knockdown of ERbeta in both cell types was sufficient to significantly decrease transcript levels of epithelial cell marker cytokeratin 8. The results of this study support the hypothesis that ERbeta acts as a tumor suppressor in mammary epithelium. Citation Information: Cancer Res 2009;69(24 Suppl):Abstract nr 4152.
Income Is an Independent Risk Factor for Worse Asthma Outcomes
Authors: Juan Carlos Cardet, Tonya S. King, Margee Louisias, Mario Castro, Christopher D. Codispoti, Ryan Dunn, Brenda L. Giles, Fernando Holguin, John Lima, Dayna Long, Njira Lugogo, Sharmilee M. Nyenhuis, Victor E. Ortega, Sima Ramratnam, Michael E. Wechsler, Elliot Israel, Wanda Phipatanakul
Journal: Journal of Allergy and Clinical Immunology (2016)
Contents
Authors: Maria Adeva, Gema Souto, Natalia Blanco, Cristóbal Donapetry, Leslie Stefanyk, Arend Bonen, David Dyck, Snezana Mirkov, Jamie Myers, Jacqueline Ramírez, Wanqing Liu, Mauricio Krause, Josianne Rodrigues-Krause, Ciara O'hagan, Giuseppe De Vito, Colin Boreham, Davide Susta, Philip Newsholme, Colin Murphy, Nancy Cortez-Espinosa, Mariana García-Hernández, Elizabeth Reynaga-Hernández, J Cortés-García, Nancy Corral-Fernández, J Guillermo Rodríguez-Rivera, Anamaría Bravo-Ramírez, Roberto González-Amaro, Diana Portales-Pérez, Wai Lee, John Mccall, Edward Gane, Rinki Murphy, Lindsay Plank, Anneke Jans, Anneke Van Hees, Ingrid Gjelstad, Lauren Sparks, Audrey Tierney, Ulf Risérus, Christian Drevon, Patrick Schrauwen, Helen Roche, Ellen Blaak, Masaru Sakurai, Koshi Nakamura, Katsuyuki Miura, Toshinari Takamura, Katsushi Yoshita, Shin-Ya Nagasawa, Yuko Morikawa, Masao Ishizaki, Teruhiko Kido, Yuchi Naruse, Yasushi Suwazono, Satoshi Sasaki, Hideaki Nakagawa
Journal: Metabolism (2012)
QuickStats: Percentage of Persons in Families Having Problems Paying Medical Bills in the Past 12 Months,* by Age Group — National Health Interview Survey, 2011–2017†
Journal: MMWR Morbidity and Mortality Weekly Report (2019)

≥65 yrsOverall * For the 2011-2017 National Health Interview Survey Family core component, a family respondent (i.e., an adult who was knowledgeable about the family) answered the question "In the past 12 months did [you/ anyone in the family] have problems paying or were unable to pay any medical bills?Include bills for doctors, dentists, hospitals, therapists, medication, equipment, nursing home, or home care." If the respondent answered "yes, " then all persons in that family were counted as being in a family having problems paying medical bills.† Estimates are based on interviews of a sample of the civilian, noninstitutionalized U.S. population and are derived from the National Health Interview Survey Family core component.From 2011 to 2017, the overall percentage of persons who were in U.S. families having problems paying medical bills in the past 12 months decreased from 19.7% to 14.6%.Similar trends were observed for all age groups, with a decrease from 23.2% to 16.8% for children aged <18 years, from 20.6% to 15.5% for adults aged 18-64 years, and from 8.9% to 7.7% for those aged ≥65 years.
Novel therapy with anti-miR-873-5p at late stages of acetaminophen overdose
Authors: Rubén Rodríguez Agudo, Pablo Fernández-Tussy, Gorka Ballesteros, David Fernández Ramos, Fernando Lopitz Otsoa, Jorge Simón, Jon Mabe, Laura Moran Blanco, Naroa Goikoetxea, Marina Serrano-Macia, Sofia Lachiondo-Ortega, Maria Mercado-Gómez, Maider Bizkarguenaga, Virginia Gutiérrez de Juan, Irene González-Recio, Marta Varela-Rey, Francisco Javier Cubero, José M. Mato, Raul J. Andrade, Maria Isabel Lucena, Luis Alfonso Martinez-Cruz, Teresa Cardoso Delgado, María Luz Martínez-Chantar
Journal: Journal of Hepatology (2020)
Leads from the MMWR. Project graduation--Maine
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hyperventilation. The vapors. Effort syndrome. Neurasthenia. Anxiety by any other name is just as disturbing
Authors: D. J. Dalessio
Journal: JAMA (1978)

WHEN Shelley wrote these lines, was he, in fact, hyperventilating? The question is moot: he would not have recognized the term in any case. The concept of hyperventilation, something of a great gooney bird, is only the latest attempt to subsume some diverse symptoms of anxiety in a word. Shelley would probably have called his affliction "the vapours." The term "vapors" is difficult for modern physicians to comprehend, since our understanding of it is that of the primary definition of the dictionary, signifying steam, gas, or visible exhalation. However, in the 19th century, the pleural of the term had a far broader meaning: to wit, a disease of nervous debility, in which a variety of strange images float in the consciousness appearing as if real—hence, hypochondriacal affections, depressions of spirit, dejection, spleen, the blues, or, to escalate again to contemporary terminology, a chronic anxiety reaction. The vapors also described a
A phase II study of extended low-dose temozolomide in recurrent malignant gliomas
Authors: Raja B. Khan, Jeffrey J. Raizer, Mark G. Malkin, Kimberley A. Bazylewicz, Lauren E. Abrey
Journal: Neuro-Oncology (2002)

Neuro-OncologyTemozolomide is an effective agent in the treatment of recurrent malignant gliomas.The standard dosage is 150-200 mg/m 2 per day for 5 days in a 28-day cycle.A prior phase I study established a chronic daily temozolomide dose that signi cantly increased the total dose administered and suggested a superior response rate.In a prospective phase II trial, we treated 35 patients with recurrent malignant gliomas with temozolomide 75 mg/m 2 per day for 42 consecutive days in a 70-day cycle.Median age was 55 years (range, 27-73 years) and median Karnofsky performance score was 70 (range, 60-90).Twenty-eight (79%) patients had glioblastoma multiforme, 3 (9%) anaplastic astrocytoma, 2 (6%) anaplastic oligodendroglioma, and 2 (6%) anaplastic oligoastrocytoma.All but one had prior radiotherapy, and 27 had prior chemotherapy.There were 2 partial (anaplastic astrocytoma) and 3 minor (glioblastoma multiforme) radiographic responses; 17 patients had progressive disease at the end of the rst cycle.In 55 cycles of temozolomide, there were 8 episodes of asymptomatic drug-related grade 3 toxicity: 6 lymphopenia, 1 neutropenia, and 1 thrombocytopenia.Median progression-free survival and overall survival were 2.5 and 8.7 months (2.
Abstract 1208: Deficiency of Interleukin-1 receptor antagonist in T cells promotes Aortic Valve Stenosis by releasing Tumor Necrosis Factor-α
Authors: Kikuo Isoda, Taizo Matsuki, Tomiharu Niida, Norio Ishigami, Harumi Kondo, Masatoshi Kusuhara, Yoichiro Iwakura, Fumitaka Ohsuzu
Journal: Circulation (2007)

The cytokine interleukin (IL)-1 is an important mediator of inflammation and cardiovascular disease. Activity of this cytokine is modulated endogenously via IL-1 receptor antagonist (IL-1Ra). We have shown that IL-1Ra-deficient (IL-1Ra −/− ) mice develop degenerative aortic valve stenosis (AS) that is the most common valvular disease in Western countries. The objective of this study is to determine the mechanisms by which deficiency of IL-1Ra may promote AS. Method and Results : IL-1Ra −/− mice (backcrossed 8 generations to the BALB/c background) and wild-type (WT) mice did not differ with regard to body weight, heart weight, and systolic arterial pressure. Furthermore, no significant differences in plasma lipid levels were observed between IL-1Ra −/− and WT mice. However histological analysis revealed that IL-1Ra −/− mice developed aortitis and showed increased aortic valve leaflet thickness compared to WT mice at the age of 12 weeks (p&lt;0.001). Echo cardiograms also revealed that IL-1Ra −/− mice displayed higher transvalvular velocities than WT mice at the age of 40 weeks (p&lt;0.01). These findings showed that IL-1Ra−/− mice spontaneously developed AS. In this study, we examined the role of T cells in development of AS by peripheral T cell transplantation. Transplantation of T cells from WT mice induced mild swelling of aortic valve leaflet in nu/nu mice. In contrast, T cells from IL-1Ra −/− mice induced an increase in aortic valve thickness in nu/nu mice. We next checked T cell function. After anti-CD3 antibody stimulation, IL-1Ra −/− T cells produced much higher levels of tumor necrosis factor (TNF)-α in culture supernatants compared to those from WT mice (p&lt;0.001). Furthermore, in IL-1Ra −/− mice, TNF-α protein levels were higher than in WT mice (106.2±12.5 vs. 216.5±12.5 pg/mL, p&lt;0.001) in vivo. Finally, we studied the roles of TNF-α in the development of AS in IL-1Ra −/− mice by generating double gene deficient (TNF-α −/− / IL-1Ra −/− ) mice. Interestingly, TNF-α −/− /IL-1Ra −/− mice did not develop AS. Conclusions : These findings suggest that IL-1Ra deficiency in T cells disrupts homeostasis of the immune system and TNF-α plays an important role in the development of AS in IL-1Ra −/− mice. These novel findings provide a clue for the development of new therapies for AS.
Adjusted Data for 2013 Birth Cohort in a Table
Authors: Ankur Pandya
Journal: JAMA (2018)

is different from the cost-effectiveness threshold used to decide whether to disinvest from an existing strategy. 6 Every dollar spent on health care has an opportunity cost.This money could have been used to fund underused cost-effective health services, invested in nonhealth sectors such as education or housing, or given back to the public in the form of lower taxes (for publicly funded health care) or higher wages (for employerbased health coverage).As Sacristán implies, the ultimate goal of disinvesting from cost-ineffective (low-value) care is not simply to save money but to reallocate limited resources to maximize population health and well-being.
ILL-CONSIDERED SENTIMENTALISM.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Highlights
Journal: JAMA (2014)

The American Board of Internal Medicine (ABIM) 10-year Maintenance of Certification (MOC) requirement took effect in 2000.In a quasi-experimental study that compared outcomes of care for 154 045 Medicare beneficiaries treated by ABIM-certified general internists-either initially certified in 1991 and subject to MOC in 2001 (n=956) or initially certified in 1989 and not subject to the MOC requirement (n=974)-Gray and colleagues found that imposition of the MOC requirement was not associated with growth in ambulatory care-sensitive hospitalizations but was associated with a small reduction in the growth of Medicare costs.In an Editorial, Lee discusses the evolution of physician certification.
New Fishbein Fellow chosen
Journal: JAMA (1980)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hypersensitivity to pollen of Olea europaea in Israel
Authors: C. Geller-Bernstein, G. Arad, N. Keynan, C. Lahoz, B. Cardaba, Y. Waisel
Journal: Allergy (1996)

The incidence of skin-tested sensitivity to olive pollen allergens among subjects with suspected atopic respiratory allergy was investigated in various populations of Israelis. This incidence was correlated with the olive cultivars, with the abundance of trees in the patients' neighborhoods, and with the history of exposure of the studied populations to olive pollen. Positive skin reactions to olive pollen, among atopic patients of the Jewish population, is rather high where olive trees are abundant (66%), and lower (29%) where trees are scarce (P<0.003). Sensitization was significantly lower (P< 0.003) among a population of Israeli atopic Arabs (16%), though these Arabs have lived in an olive-rich area for several generations.
Obstetrics and gynecology
Authors: H. G. McQuarrie
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phase II Study of Twice-Daily High-Dose Thoracic Radiotherapy Alternating With Cisplatin and Vindesine for Unresectable Stage III Non–Small-Cell Lung Cancer: Japan Clinical Oncology Group Study 9306
Authors: Ikuo Sekine, Yutaka Nishiwaki, Takashi Ogino, Akira Yokoyama, Mari Saito, Kiyoshi Mori, Iwao Tsukiyama, Satoshi Tsuchiya, Kazushige Hayakawa, Kimio Yoshimura, Naoki Ishizuka, Nagahiro Saijo
Journal: Journal of Clinical Oncology (2002)

PURPOSE: To evaluate the efficacy and toxicity of high-dose thoracic radiotherapy (TRT) alternating with chemotherapy (CH) for unresectable stage III non–small-cell lung cancer (NSCLC). PATIENTS AND METHODS: Forty-one patients received TRT with 1.5 Gy twice daily, 5 days a week, on weeks 1, 2, 5, 6, and 9, up to a total dose of 66 to 72 Gy, alternating with cisplatin 80 mg/m 2 on day 1 and vindesine 3 mg/m 2 on days 1 and 8, repeated every 4 weeks, for two or three courses beginning on week 3. RESULTS: The median (range) total dose of TRT and number of CH courses were 72 Gy (16.5 to 72 Gy) and three (zero to three), respectively. Delay in TRT ≥ 5 days was observed in 24 (75%) of 32 patients who completed the projected treatment, due to leukopenia in 12, esophagitis in seven, infection in two, and other causes in three patients. Partial responses were obtained in 36 patients (88%). The median survival time and 3- and 5-year survival rates were 18.4 months, 24%, and 10%, respectively. Grade 3 or 4 leukopenia and esophagitis developed in 32 and seven patients, respectively. Grade 3 or 4 late esophageal toxicity developed in two patients. CONCLUSION: Alternating high-dose TRT and CH for stage III NSCLC produced a high response rate with median and long-term survival comparable to prior trials utilizing standard approaches in this population. Acute and late esophageal toxicity was observed and interruption of TRT was required in most of the patients.
Hypoglycemic Disorders
Authors: F J Service
Journal: New England Journal of Medicine (1995)

Hypoglycemia is a clinical syndrome with diverse causes in which low levels of plasma glucose eventually lead to neuroglycopenia. This review will be devoted to hypoglycemic disorders that do not result from the treatment of diabetes mellitus.Glucose CounterregulationIn healthy persons, postabsorptive levels of plasma glucose stay within a narrow range (about 60 to 100 mg per deciliter [3.3 to 5.6 mmol per liter]) despite the intermittent ingestion of food. Insulin, the primary regulatory hormone that blunts postprandial hyperglycemia and maintains postabsorptive euglycemia, has its effects counterbalanced by several factors that provide a minimal level of glycemia in order . . .
Rates of caesarean vary widely across Europe
Journal: BMJ (2015)

states that the World Health Organization advises "there is no justification for any region to have a caesarean rate higher than 10-15%."However, this recommendation was made in 1985, and WHO's latest guidance on caesarean rates was published in April 2015 1 .In this latest statement, WHO does not recommend a specific caesarean section rate at a country level.The statement cites research showing that when caesarean section rates rise towards 10% across a population, the number of maternal and newborn deaths decreases; yet when the rate goes above 10%, there is no evidence that mortality rates improve.
CRITERIONS OF PRACTICE FOR MEDICAL SECTS.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
UNIQUE FOOD PRESERVATION
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal