tbuckley/cabot-search huggingface dataset:
Pulmonary Autograft Versus Aortic Homograft for Rereplacement of the Aortic Valve
Authors: Gerald S. Carr-White, Sally Glennan, Sue Edwards, Francis D. Ferdinand, Anthony C. Desouza, John R. Pepper, Magdi H. Yacoub
Journal: Circulation (1999)

Background —The use of a pulmonary autograft for rereplacement of the aortic valve has both potential advantages and disadvantages. This study details the early results of a subset of patients enrolled in a prospective randomized trial comparing pulmonary autografts and aortic homografts who have had previous aortic valve replacements. Methods and Results —A total of 47 patients who had undergone ≥1 previous aortic valve replacement were randomized to receive either a pulmonary autograft (24 patients aged 40±11 years) or an aortic homograft (23 patients aged 37±11 years) for rereplacement of the aortic valve. One early death occurred in the homograft group, and 1 late (7 months) death occurred in the autograft group. One patient who received a pulmonary autograft was reoperated on for inflammatory pulmonary stenosis. One patient in each group was reopened for bleeding (both within 24 hours). Two patients in the autograft group had postoperative neurological weakness; they fully recovered over 2 months. Hospital stay, blood loss, incidence of perioperative arrhythmia, and markers of coronary ischemia were similar between the 2 groups. At 6-month follow-up (range, 1 to 12 months), left ventricular end-diastolic diameter was similar in both groups (homografts, 5.0±0.9 cm; autografts, 5.2±0.6 cm; P =NS), and no patient in either group had significant aortic valve dysfunction. Conclusions —Rereplacement of the aortic valve with a pulmonary autograft is feasible and safe in patients aged 14 to 60, regardless of their preoperative diagnosis or clinical condition.
The glycosaminoglycan-binding domain of PRELP acts as a cell type–specific NF-kB inhibitor that impairs osteoclastogenesis
Authors: Nadia Rucci, Anna Rufo, Marina Alamanou, Mattia Capulli, Andrea Del Fattore, Emma Åhrman, Daria Capece, Valeria Iansante, Francesca Zazzeroni, Edoardo Alesse, Dick Heinegård, Anna Teti
Journal: The Journal of Experimental Medicine (2009)
Faecal incontinence.
Authors: M Swash
Journal: BMJ (1993)

control over the fees that patients pay.Fierce disagreement within the General Practitioners' Association over whether doctors should sign contracts with the new authorities resulted in the resignation of the association's chairman and executive and the election of a more conservatively inclined group.The government retreated on the issue and agreed to continue present arrangements for those who oppose contracts.Concerns in the public hospital sector centre on the commercialisation of the health service.The secrecy now surrounding management decisions has been heavily criticised as inappropriate for a publicly funded service.Fees for hospital care were introduced earlier than other changes and provided fuel for those concerned about possible privatisation.The strong negative public reaction led the government to abandon the inpatient fees, although charges for outpatient services remain.5The full potential of the restructuring will remain untested for the next few months.The problem for the government is that, with no additional money for extra services, any substantial change in the provision of services is also likely to be controversial.The disadvantages of change will get immediate (pre-election) publicity: any gains are likely to become apparent only in the long term (after the election).This may partly explain the current preoccupation with image-the appearance of change is important to justify the costs of the restructuring, but real change, which might upset powerful interest groups, will be avoided until after the election.We do not yet know whether the image will reflect reality.
Marriage Therapy
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
BOOK REVIEWS
Authors: N. L. HARRIS
Journal: JNCI Journal of the National Cancer Institute (1992)

Journal Article BOOK REVIEWS Get access Lymphoproliferative Diseases D. B. Jones , D. H. Wright , eds. Dordrecht , The Netherlands : Kluwer Acad. Publ ., 1990 . 216 pp., illus. Immunology and Medicine Series, Vol. 15 NANCY L. HARRIS NANCY L. HARRIS Department of Patholoy, Massachusetts General HospitalBoston, MA 02114 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 84, Issue 8, 15 April 1992, Pages 640–641, https://doi.org/10.1093/jnci/84.8.640-a Published: 15 April 1992
TYPHOIDAL CHOLECYSTITIS AND CHOLELITHIASIS.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Clarification.
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hypertension
Authors: Janet M. Torpy
Journal: JAMA (2010)

HypertensionH ypertension, also known as high blood pressure, affects hundreds of millions of persons worldwide.In the United States alone, more than 65 million individuals have hypertension.High blood pressure, if left untreated, can cause severe damage to the body' s organs, including the brain, heart, blood vessels, and kidneys.Having high blood pressure may not cause symptoms until organs have been damaged.For this reason, hypertension is often called the "silent killer."The May 26, 2010, issue of JAMA contains an article about hypertension and its treatment in the United States during a recent 20-year period.
Does ventricular triggered atrial (AVT) pacing mitigate hemodynamic collapse during ventricular tachyarrhythmia? S. Dinakar Satti, G. Muqtada Chaudhry, Craig S. Vinch, David Casavant, Thomas F. Marchese, Charles I. Haffajee, St. Elizabeth's Medical Center of Boston, Boston, MA, Medtronic Inc, Minneapolis, MN
Journal: Journal of the American College of Cardiology (2001)
Investigations Into the Cause of Mental Deficiency
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Oncology
Authors: Eugene M. McKelvey
Journal: JAMA (1981)

The dramatic therapeutic responses that have been achieved in patients with leukemia, lymphoma, and certain other tumors have led to increased anticipation for the treatment of all patients with malignant disease. While major developments have occurred in different areas of clinical oncology, this past year has been characterized as one of direct clinical application of advances in basic science and technology. In addition, the lessons learned from the treatment of one type of cancer have been incorporated into the management of other forms of malignant neoplasms. <h3>Cancer Detection</h3> The ability to diagnose, stage, and monitor malignant disease accurately is an essential part of the care of patients with cancer. Recent progress in this area has been made with the use of radiolabeled antibodies to specific tumor markers. Historically, the detection and serological quantitation of selected tumor-markers have proved to be of limited clinical value because of lack of specificity and
Retinoblastoma in 52-Year-Old Man
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The physiology of cardiopulmonary resuscitation. An update
Authors: A. B. Sanders
Journal: JAMA (1984)

WHILE great strides have been made in the care of patients who suffer cardiac arrest, there is much room for improvement. The basic technique of cardiopulmonary resuscitation (CPR) has changed little since Kouwenhoven and colleagues<sup>1</sup>introduced it in 1960. The present standard was set by a committee of experts at the National Conference on Cardiopulmonary Resuscitation and Emergency Cardiac Care in 1973<sup>2</sup>and updated in 1979.<sup>3</sup>How successful has this technique been? Recent studies have shown that patients suffering in-hospital cardiac arrest have a 14% to 24% chance of being discharged alive.<sup>4,5</sup>This past year, Bedell and associates<sup>4</sup>reviewed 294 consecutive patients who underwent CPR in a university hospital in Boston. Only 41 patients were discharged alive; many who died, however, had serious underlying medical problems. DeBard<sup>5</sup>reviewed 1,073 cases of patients undergoing CPR in a community hospital in Dayton, Ohio. Fifty-six percent of patients
Nutrition and sleep.
Journal: BMJ (1972)

no significant difference has been found between survival in the two groups in clinical stage I cases, those with stage II tumours showed a statistically better survival in the radical mastectomy group at 10 years, though this was not seen after 5 years.A significantly greater rate of local recurrence was observed in the tylectomy group than in those undergoing radical mastectomy, but there was a higher incidence of lymphoedema of the arm in the radical mastectomy group.Only when all the permutations and combinations of treatments carried out in various centres on patients with breast cancer have been submitted to such thoroughly con- trolled investigation will surgeons be in a position to judge the best possible treatment for an individual patient with this disease.
Transactions of the Forty-sixth Annual Meeting of the Ohio State Medical Society.
Journal: JAMA (1892)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PHRENITIS PROSTATICA
Authors: JAMES F. PERCY
Journal: JAMA (1910)

Affections of the mind proceeding from the pathologic prostate gland have had no place in the literature of disease until 1907.<sup>1</sup>Before this date, the prostate had been considered only from the standpoint of urinary obstruction and infection. It is the purpose of the present paper to emphasize the surgical importance of the prostate along medicolegal lines. I can do this best, perhaps, by detailing the history of a recent case. By way of preface, permit me to say that this history is not an uncommon one. The difficulty has been to attribute the cause of the trouble to its source, viz., the diseased and usually hypertrophied prostate. Mr. X, aged 66, has a history of prostatic irritation extending over a period of ten years; voids urine three to four times during each night; does not use catheter; amount of residual urine unknown; urine normal except for occasional hyaline
Herzkrankheiten. Band I: Physiologie, Beurteilung und funktionelle Pathologie des Herzens
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Little Battles
Authors: Robert Malcolm
Journal: JAMA (1990)

It's about 6 PM and I sit down for the first time in 3 hours. My time in combat is over for another day. Four admissions today: Two angry young men in their 30s who are addicted to cocaine and feel they use alcohol only to mellow out. A 15-year-old girl who smokes 10 to 15 joints a day and who—with the exception of cannabis—probably has not put a single new thing in her brain in more than 3 years. A 45-year-old physician's wife who has had five abdominal operations, massive addiction to prescription narcotics, and a profound depression. I have written orders for all four. The work earlier in the day was a sick call for those patients who were previous casualties of this war on drugs. Patients with psychotic depression, second-degree burns, "flu"like illness, and chronic pain syndrome were some of the convalescent wounded. The victims of this
ATRT-36. META-ANALYSIS OF TREATMENT MODALITIES IN METASTATIC ATYPICAL TERATOID/RHABDOID TUMORS IN CHILDREN
Authors: Reena Underiner, Mostafa Eltobgy, Joseph Stanek, Jean Michaud, Wafik Zaky, Eric Bouffet, Jonathan Finlay, Mohamed AbdelBaki
Journal: Neuro-Oncology (2018)

Metastatic central nervous system (CNS) atypical teratoid/rhabdoid tumors (AT/RT) in children represent around 20% of newly-diagnosed AT/RT cases, and are associated with dismal prognosis. We investigated the efficacy of different treatment modalities associated with best outcomes in the management of metastatic AT/RT. A comprehensive analysis of 2,122 peer-reviewed manuscripts revealed 45 studies with a total of 132 metastatic AT/RT patients. Additionally, 8 patients were included from chart review performed at Nationwide Children’s Hospital. The 3-year overall survival (OS) was 26% (95% confidence interval (CI): 18–34%). Age at diagnosis significantly impacted the OS (p=0.0225); the 3-year OS for patients <18 months was 21%, compared to 28% for patients 18–36 months and 33% for patients >36 months. Gross total resection of the primary tumor was not associated with significant improvement in the OS (p = 0.866). On univariate analysis, radiation therapy (RT), intrathecal chemotherapy (IT), and marrow-ablative chemotherapy followed by autologous hematopoietic progenitor cell rescue (AuHPCR) had a significant impact on OS, respectively (p<0.0001, p<0.05, p<0.0001). These results were further supported by multivariable analysis, in which RT (p<0.0001), IT (p=0.0227), and AuHPCR (p<0.0001) were all independently associated with reduced risk of death. Multimodal treatment approach should be incorporated in the management of metastatic AT/RT in children, and may include AuHPCR with adjuvant RT and IT. Given the rarity of published research focused on metastatic AT/RT, these conclusions may be an important step towards the creation of standard treatment guidelines for metastatic AT/RT patients.
Application of toxicogenomic analysis to risk assessment of delayed long-term effects of multiple chemicals including endocrine disruptors in human fetuses
Authors: Chisato Mori, Masatoshi Komiyama, Tetsuya Adachi, Kenichi Sakurai, Daisuke Nishimura, Kyoka Takashima, Emiko Todaka
Journal: Environmental Health Perspectives (2002)
The impact of cutting balloon angioplasty for the treatment of diffuse in-stent restenosis. Comparison with conventional balloon angioplasty Raisuke Iijima, Masato Nakamura, Yoko Kitagawa, Rintaro Nakajima, Takashi Yoshitama, Takuro Takagi, Hitoshi Anzai, Tarou Tunoda, Tetsu Yamaguchi. Third Department of Internal Medicine Toho University School of Medicine, Tokyo, Japan
Journal: Journal of the American College of Cardiology (2001)
Myopic Hypotheses
Authors: Lawrence Cohen
Journal: JAMA (1972)

<h3>To the Editor.—</h3> I could hardly believe my myopic eyes when I read "Myopia and Dental Caries" (<b>218</b>:1572, 1971). Despite the fact that I have read the LETTER a number of times I still cannot decide whether the writers are serious. Dental caries is a disease caused by bacteria. In germ-free rats caries does not occur, as Orland and his coworkers<sup>1</sup>showed. In the group of freshmen studied by Goldstein et al and whose ages ranged from 20 to 31 years, the carious lesions present would have commenced in pits and fissures of enamel and on the smooth surfaces of enamel interproximally.<sup>2</sup>The important point is that in those subjects the carious process first involved the enamel, an ectodermal derivative, containing 96% inorganic material and 4% organic material and water. The organic material is a keratin-like substance. By extension the carious process involved the dentine. The "proteolytic