tbuckley/cabot-search huggingface dataset:
Abstract 10906: Heart Failure is Common and Under Recognized in Patients With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
Authors: Nisha A Gilotra, Abhishek Sawant, Aditya Bhonsale, Anneline S te Riele, Cynthia A James, Brittney Murray, Crystal Tichnell, Daniel P Judge, Stuart D Russell, Hugh Calkins, Ryan J Tedford
Journal: Circulation (2015)

Introduction: The reported incidence of heart failure (HF) in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) varies depending on study cohort ranging from &lt;10 to 20%. Though risk of fatal arrhythmias is well described, the heterogenous manifestations of HF in this population are less well known. Hypothesis: With more prompt recognition of ARVD/C and subsequent prevention of SCD, HF is becoming more prevalent amongst ARVD/C patients. Methods: Patients from the Johns Hopkins ARVD/C Program Registry meeting the 2010 Revised Task Force Criteria with completed HF symptom survey (n=134) and/or available HF clinical assessment (n=154) were included. HF signs and symptoms were retrospectively adjudicated. Results: Of the 288 patients studied, 236 had evidence of structural heart disease defined as right ventricular (n=199) or biventricular dilatation/dysfunction (n=37). At least one clinical sign or symptom of HF was present in 123 (52%) of those with structural disease (42 had one and 61 had two or more signs/symptoms). The most commonly reported symptoms were dyspnea on exertion (n=87) and fatigue (n=77). Evidence of volume retention (edema or ascites) was found in 46/236 (20%), and left-sided HF symptoms were rare. Of the 105 patients with structural heart disease and known age at HF symptom onset, average time from first ARVD/C presentation to HF symptoms was 6.3 ± 8.0 years, and 40% had at least one episode of sustained ventricular tachycardia or ICD shock prior to HF symptoms. Presence of a genetic mutation for ARVD/C did not correlate with HF symptoms or structural changes. Sixteen patients underwent orthotopic heart transplant. Conclusions: HF symptoms are common in the ARVD/C population with structural heart disease. Though there is a small subset of patients with evident volume overload requiring therapy, there is a larger portion of patients with HF symptoms that may be under recognized.
Morphological study of vascular dissemination in a metastatic hepatocellular carcinoma model in the monkey
Authors: C Lindsay
Journal: Hepatology (1997)

In this report we describe a metastatic monkey hepatocellular carcinoma (HCC) model in which intravascular metastatic development is clearly evident. The tumor-bearing livers contained intravenous tumor thrombi at different stages of progression within the small branches of the portal vein. These ranged from mural tumor thrombi lined with CD31-positive endothelial cells to tumor thrombi that had completely occluded the vascular lumen. Intravenous tumor expansion was frequently accompanied by the appearance of CD31-positive microvessels within the tumor thrombi and fibrous perivascular thickening, giving rise to isolated tumor nodules within the portal areas. Intravascular expansion of disseminating HCC was also evident within small branches of the pulmonary arteries in the lungs. These findings indicate that metastases of HCC can become established while still at an intravascular stage, suggesting that the direct interaction between tumor cells and parenchymal cells predicted from experimental rodent metastasis models is not a prerequisite for the metastatic development of these tumors.
Jargon
Authors: C. G. Roland
Journal: JAMA (1968)

In scientific writing, jargon comprises two major subdivisions. Although these may overlap and cause confusion, at their extremes they are easily distinguished. One subdivision is that of technical language; the other includes the pejorative or contemptuous connotations of jargon. That part of so-called jargon which we recognize as technical language is an acceptable and necessary part of scientific communication. Because of this I would suggest to the lexicographers that we stop using the word jargon to mean technical language, and limit "jargon" to its pejorative uses, many of which result from the abuse of technical language. Every profession and trade has its technical language, a private tongue intelligible only to initiates. Technical language serves a function which ordinary language cannot serve, or at least cannot serve without excessive wordiness. But a private language is jargon if it replaces ordinary language only to exclude persons not belonging to the clique who
Dapsone
Authors: J. O'D. Alexander
Journal: British Journal of Dermatology (1972)

Journal Article Dapsone Get access J. O'D. Alexander J. O'D. Alexander Department of Dermatology, Glasgow Royal Infirmary, 84 Castle Street, Glasgow, C.4 Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 86, Issue 3, 1 March 1972, Page 312, https://doi.org/10.1111/j.1365-2133.1972.tb02238.x Published: 01 March 1972
Correction
Journal: BMJ (1963)

and grow as it should do.The key sentence in Dr. Allen's letter is, " Further finance must be made avail- able."The key fact of life in Britain in the 1960s is that not much further finance for such expansion is going to come from the Treasury.Where is it going to come from ?Directly from the pockets of the public is the only answer, highly unpalatable though this answer is.Having paid heavily
THE GLOMERULAR CIRCULATION OF THE KIDNEY
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diseases of Women.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Social Adjustment.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE ASSOCIATION TREASURER'S NOTICE.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Radiography of injured arms and legs in eight accident and emergency units in England and Wales. Royal College of Radiologists Working Party.
Journal: BMJ (1985)

The use of radiography of the arms and legs (extremity radiography) in 32936 patients attending eight accident and emergency units was studied. Although extremity radiography was satisfactory in terms of cost per bony injury detected (40 pounds), considerable differences between centres in the predicted and actual yields of bony injury were observed. Guidelines for selection of patients for extremity radiography would reduce variability in its use and improve the quality of present practice.
THE ACTION OF ALKALIES ON HUMAN GASTRIC DIGESTION.
Journal: JAMA (1893)

The frequency with which bicarbonate of soda is employed in gastric affections renders any contribution that enhances our knowledge of its action of interest to the profession. Dr. G.Linossierand Dr. G.Lemoinehave published in the June number of the<i>Archives Générales de Medicine</i>a valuable paper detailing the results of certain observations regarding the action of bicarbonate of soda and of carbonate of lime in a case of merycismus. Test meals consisting of 80 grams of bread, 80 grams of meat, and 250 grams of water were eaten by the patient, and every hour samples of chyme were obtained from the mouth into which it entered by the process of rumination. Under ordinary conditions in this patient the total acidity of the chyme was slightly pronounced, diminishing from the first to the third hour after a meal; the hydrochloric secretion was also sensibly inferior to normal, and
Antidepressant medications. A more effective use by general practitioners, family physicians, internists, and others
Authors: N. S. Kline
Journal: JAMA (1974)

DEPRESSION is the most undertreated of all major diseases. Were pneumonia, diabetes, or any other important disease entity so often undiagnosed and so often untreated, the courts would justifiably be filled with patients suing for medical malpractice. The discrepancy between the<i>availability</i>of treatment for depression and the actual<i>providing</i>of treatment is so great as to constitute a scandal. According to the National Institute of Mental Health (NIMH), a recent survey estimates that in any given year 15% of adults between the ages of 18 and 74 years may suffer serious depressive symptoms. This represents approximately 20 million individuals. It is not possible to secure figures for an unduplicated count, but NIMH estimates that in 1971 about 615,000 individuals (less than 5% of those in need of treatment) were resident in or admitted to psychiatric treatment facilities of one kind or another. This represents only a small portion of
Counterpulsation for intraoperative cardiogenic shock. Successful use of intra-aortic balloon
Authors: L. B. Housman
Journal: JAMA (1973)

Intra-aortic balloon counterpulsation has been used successfully in the treatment of cardiogenic shock following cessation of cardiopulmonary bypass in four patients, three of whom had an aortocoronary bypass and one, an aortic valve replacement. In each patient, systolic blood pressure could not be maintained above 60 mm Hg after an extensive trial of vasopressor therapy. The balloon catheter was inserted through a graft sewn onto the femoral artery and the effect of heparin sodium was reversed with protamine sulfate; no further anticoagulation was carried out. The hemodynamic status improved immediately in all four patients and counterpulsation was discontinued in two to five days. All four patients survived and were discharged from the hospital.
MINIMUM STANDARDS OF ORGANIZATION FOR MUNICIPAL HEALTH DEPARTMENTS
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Marriages
Journal: JAMA (1946)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
New funds for Huntington's disease research
Authors: P. Gunby
Journal: JAMA (1980)

In the 13 years since folk singer and composer Woody Guthrie died of Huntington's disease, it has become apparent that this hereditary neuromuscular disorder is not so rare as once supposed. Now, in addition to ongoing research, the US Department of Health and Human Services (DHHS) is adding two new research programs on this disease and similar disorders. The new funds, totaling $5.1 million, are an answer to one recommendation of the Commission for the Control of Huntington's Disease and Its Consequences, which made a report to Congress in October 1977. The money will be administered in the form of grants from the DHHS' National Institute of Neurological and Communicative Disorders and Stroke (NINCDS), Bethesda, Md. Donald B. Tower, MD, institute director, says the grants will provide a "center-without-walls" approach consisting of investigators engaged in basic or clinical research in different departments of a university or at different universities and
Prevalence and predictors of posttraumatic stress disorder in adult survivors of childhood cancer: A report from the Childhood Cancer Survivor Study
Authors: M. Stuber, K. Meeske, B. Zebrack, K. Krull, K. Stratton, W. Leisenring, L. Robison, L. Zeltzer
Journal: Journal of Clinical Oncology (2009)

CRA10002 Background: This study examined prevalence and demographic- and disease-related correlates of posttraumatic stress disorder (PTSD) among 6,542 adult childhood cancer survivors and 368 siblings from the Childhood Cancer Survivor Study. Methods: Subjects were dichotomized based on full PTSD criteria, using the Foa PTSD self-report measure to assess posttraumatic stress symptoms of intrusion of unwanted memories, avoidance of event reminders, and increased startle response, and the Brief Symptom Inventory-18 and the SF-36 subscale, role limitation due to emotional health, to evaluate clinical distress or impaired function. A self-report questionnaire provided demographic information and medical abstraction provided cancer reatment data. Multivariable generalized linear models were used to compare prevalence of PTSD among cancer survivors to siblings and to examine relationships between PTSD and demographic and disease-related factors. Relative risks (RR) were calculated based on a Poisson distribution with robust error variances. Results: Five hundred eighty-nine (9%) childhood cancer survivors and 8 (2%) siblings met criteria for a diagnosis of PTSD (RR = 3.83, 95% CI 1.96–7.48, p < 0.0001). Among cancer survivors, there was significantly more PTSD reported by women from minority backgrounds (p < 0.05). Other demographic factors associated with PTSD were having less than a college education (p < 0.05), being unmarried (p < 0.001), having an annual income less than $20,000 (p < 0.05) and being unemployed (p = 0.001). Risk of PTSD was significantly higher for survivors diagnosed at ages 15 to 20 years (p < 0.05). PTSD was more common among survivors treated with intensive chemotherapy (p < 0.05) or radiation therapy (p < 0.001) and who relapsed or developed a second malignant neoplasm (p < 0.001). Neuroblastoma and Wilms tumor survivors had a significantly lower risk of PTSD than did leukemia survivors (p < 0.05). Conclusions: While the majority of childhood cancer survivors did not demonstrate PTSD, a clinically significant number did meet diagnostic criteria. Prospective assessment of survivors with high risk demographic-, diagnosis-, and treatment-related characteristics should be considered as part of long-term health screening. No significant financial relationships to disclose.
Is animal experimentation being threatened by animal rights groups?
Authors: F. Rosner
Journal: JAMA (1985)

THROUGHOUT history, animals have played an important role in man's understanding of himself and his environment. A wide variety of animal "models" have made invaluable contributions to the understanding, treatment, and cure of human diseases. The discovery and identification of hormones and vitamins and the testing of most antibiotics and chemicals would have been impossible without such experiments. Humane considerations in the use of experimental animals have been discussed, often with considerable vigor, for more than a century. The place and importance of the experimental animal in medicine today is hotly disputed by the antivivisectionists who question the use of animals at all and the scientific community. The animal rights movement has become increasingly vocal and violent during the past two years with break-ins at research institutions, destruction of property, and the stealing of animals. Activities by American animal protection groups have increased sharply
Isoniazid-resistant tuberculosis. A community outbreak and report of a rifampin prophylaxis failure
Authors: J. R. Livengood
Journal: JAMA (1985)

The choice of effective preventive treatment for persons exposed to<i>Mycobacterium tuberculosis</i>resistant to isoniazid is uncertain. Although no data document the efficacy of any drug other than isoniazid for preventive treatment of tuberculosis, rifampin, with or without ethambutol, has been used for prophylaxis in contacts of cases with known isoniazid-resistant organisms. This report describes a community outbreak of isoniazidresistant tuberculosis infection and a case of rifampin prophylaxis failure with acquired rifampin resistance. This raises concern about the efficacy of rifampin for the preventive treatment of contacts exposed to isoniazidresistant tuberculosis. (<i>JAMA</i>1985;253:2847-2849)
Respiratory Viruses and Respiratory Virus Vaccines
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
2015 SPCTPD/ACC/AAP/AHA Training Guidelines for Pediatric Cardiology Fellowship Programs (Revision of the 2005 Training Guidelines for Pediatric Cardiology Fellowship Programs): Introduction
Authors: Robert D. Ross, Michael Brook, Peter Koenig, Jeffrey A. Feinstein, Peter Lang, Robert L. Spicer, Julie A. Vincent
Journal: Journal of the American College of Cardiology (2015)