tbuckley/cabot-search huggingface dataset:
Report of the Board of Health of the State of Alabama for the year 1895.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
<i>Announcement</i>: National Teen Driver Safety Week — October 16–22, 2016
Journal: MMWR Morbidity and Mortality Weekly Report (2016)

Motor vehicle crashes are the leading cause of death for teens in the United States.In 2014, a total of 2,450 teens and young adults aged 15-19 years died in motor vehicle crashes, and approximately 288,000 were treated in emergency departments or hospitalized for injuries (1).In the last decade, motor vehicle crash deaths and injuries among teens decreased significantly (1); however, projections for 2015 data indicate a 10% increase in fatalities among persons aged 15-20 years (2).The 2016 National Teen Driver Safety Week will be observed October 16-22, 2016.This year's theme, "Talk to Your Teen About the '5 to Drive,'" encourages families to agree upon the rules to address driving risks for teens, including alcohol use, not using seat belts, distracted driving, speeding, and teen passengers (3).According to teens, parents can have the most influence on driving habits by demonstrating skills and setting limits (4).Parent-imposed rules and limits can reduce the risk for teens being involved in a crash or other negative driving outcomes (4,5).Online resources are available to help parents in supervising their new driver and monitoring and reinforcing the "rules of the road" as their teen begins driving independently.A Parent-Teen Driving Agreement (http:// www.cdc.
Smallpox in Philadelphia.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Meta-Analysis
Authors: SAMUEL NEFF
Journal: Annals of Internal Medicine (1987)

Letters and Corrections1 November 1987Meta-AnalysisSAMUEL NEFF, M.D.SAMUEL NEFF, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-107-5-791_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Readers of Douglas Hofstadter (1), logicians, and others will be amused by the publication of an analysis of meta-analysis, a meta-meta-analysis (2, 3). This letter, a commentary on those papers, is therefore an example of meta-meta-meta-analysis. As the previous authors point out, at each higher level new biases are introduced: publication bias and selection bias for the source studies, and publication bias for the meta-analysis itself (positive or "interesting" meta-analyses may be preferentially published).It seems agreed that the need for meta-analysis has been created by the proliferation of studies that disagree, by sample sizes that are...References1. HOFSTADTER D. Godel, Escher, Bach: An Eternal Golden Braid. Random House: New York; 1979. Google Scholar2. L'ABBEDETSKYO'ROURKE KAK. Meta-analysis in clinical research. Ann Intern Med. 1987;107:224-33. LinkGoogle Scholar3. SACKSCHALMERS HT. Meta-analysis of randomized control trials (RCT's) [Abstract]. Clin Res. 1985;33:525A. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New England Medical Center Boston, MA 02111 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByMeta-AnalysisBernard Choi, PhD 1 November 1987Volume 107, Issue 5Page: 791-791 Issue Published: 1 November 1987 PDF DownloadLoading ...
Effects of massive transfusion of blood on acid-base balance
Authors: R. D. Miller
Journal: JAMA (1971)

No correlation was observed between the amount of stored acid-citrate-dextrose blood administered and magnitude of negative base excess measured in 20 patients, some in shock and some not. Extreme variability in acid-base response to multiple blood transfusion would appear to make routine bicarbonate administration unadvisable. Four of five patients receiving greater than 100 mEq of sodium bicarbonate intraoperatively had postoperative arterial pH of greater than 7.48. Only two of 11 patients who received less than 100 mEq of sodium bicarbonate intraoperatively had postoperative arterial pH values greater than 7.48. Because of an undesirable shift of the oxygen dissociation curve to the left with an alkaline pH, it is suggested that bicarbonate therapy should be reserved for patients with severe metabolic acidosis (base excess, —7 mEq/liter or more) which can be established only by analysis of arterial blood for arterial carbon dioxide tension and pH.
Urinary Cadmium and Blood Pressure: Results from the NHANES II Survey
Authors: Alice S. Whittemore, Yasamin DiCiccio, George Provenzano
Journal: Environmental Health Perspectives (1991)

Relationships between urinary cadmium levels and blood pressure were examined in a sample of 951 adult men and women who participated in the Second National Health and Nutritional Examination Survey (NHANES II). Among all participants, positive relationships were seen between urinary cadmium levels and both systolic and diastolic blood pressure (p less than 0.05 and p less than 0.01, respectively), after adjusting for age, sex, race, relative body weight, smoking status, and hypertensive medication use. However, analyses for subgroups determined by sex and smoking status were inconsistent. Among current smokers, urinary cadmium levels were significantly positively associated with both systolic and diastolic blood pressure for women, and with diastolic blood pressure for men. Yet among former smokers and lifelong nonsmokers of both sexes, urinary cadmium was not significantly associated with either systolic or diastolic blood pressure. Evidence that some hypertensive medications increase urinary cadmium excretion suggests that the positive associations seen among current smokers may reflect high urinary cadmium levels among hypertensives induced by hypertensive treatment. After treated hypertensives were removed from the analysis, regression coefficients relating blood pressure to cadmium dropped by a factor of two and lost statistical significance. We conclude that the present data provide little support for a causal association between systemic cadmium and hypertension at nonoccupational exposure levels. Further, conflicting results of previous studies may reflect failure to control adequately for age, smoking status, and hypertensive treatment.
CCL24 modulates fibrosis development in primary sclerosing cholangitis: correlation of human serum CCL24 levels with fibrosis markers and data from the Mdr2–/– mouse model.
Authors: Neta Barashi, Michal Segal, Arnon Aharon, Avi Katav, Adi Mor, Inbal Mishalian, Devorah Olam, Amnon Peled, Francesca Saffioti, Douglas Thorburn
Journal: Journal of Hepatology (2020)
THE EVOLUTIONARY SPIRIT FOR BETTERMENT IN MEDICAL EDUCATION
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Praxis of Urinary Analysis. A Guide to the Chemical Analysis of Urine. With Directions for Preparing Artificial Pathologic Urines for Practicing the Various Tests, and an Appendix on the Analysis of Stomach Contents.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use
Authors: Deepak L. Bhatt, James Scheiman, Neena S. Abraham, Elliott M. Antman, Francis K.L. Chan, Curt D. Furberg, David A. Johnson, Kenneth W. Mahaffey, Eamonn M. Quigley, Robert A. Harrington, Eric R. Bates, Charles R. Bridges, Mark J. Eisenberg, Victor A. Ferrari, Mark A. Hlatky, Sanjay Kaul, Jonathan R. Lindner, David J. Moliterno, Debabrata Mukherjee, Richard S. Schofield, Robert S. Rosenson, James H. Stein, Howard H. Weitz, Deborah J. Wesley
Journal: Journal of the American College of Cardiology (2008)
Dermabrasion
Authors: Cyril H. March
Journal: JAMA (1969)

<h3>To the Editor:—</h3> In "Present Status of Dermabrasion" by Ervin Epstein, MD, (<b>206</b>:607, 1968), although many of the statements made are entirely correct, the tone of the article is not suitable for a scientific publication which has a wide-spread distribution. We should like to comment on the following statements by Dr. Epstein: It is difficult to reconcile "status of dermabrasion for cosmetic purposes can be summed up by a single word—deceased," with "if performed properly in the proper places, planing can be valuable." The cost can hardly be compared with that of a "life saving" appendectomy. The fees charged for cosmetic procedures have always been relatively high, because they are performed by highly trained specialists. The "survey" by mail on his first 50 dermabraded patients resulted in one single answer by a patient who said that, "as far as the scarring is concerned, there has been
Confidentiality expectations of patients, physicians, and medical students
Authors: B. D. Weiss
Journal: JAMA (1982)

One hundred seventy-seven patients, 53 medical students, and 109 house staff were surveyed by questionnaire regarding the confidentiality of information that patients give to physicians. Physicians and students reported discussing cases in situations in which most patients did not expect this to occur. These included discussions at parties (36% v 9%) and with spouses (51%<i>v</i>17%), and identification of patients by name (60%<i>v</i>23%). Both patients and medical personnel thought it was common to discuss cases with other physicians, even at large meetings, for additional opinions or because of interest. However, patients were less likely than physicians to think that this occurred (90%<i>v</i>51%). Medical students in their first 60 days of training responded more like physicians than like the lay public. Physicians responded similarly at various levels of training. Primary<i>v</i>non-primary care physicians showed no differences in response. (<i>JAMA</i>1982;247:2695-2697)
Modeling Exposure Routes to Man of Trace Metals Associated with Acid Precipitation
Authors: B. G. Bennett
Journal: Environmental Health Perspectives (1985)

Pollutant metals released to the environment disperse and interact in various ways before arriving at sensitive receptors. Modeling of pollutant behavior may be by time-dependent or time-independent means. The time-independent, exposure commitment method requires a less extensive data base and can begin with general associations between environmental concentrations or fluxes. Such assessments for representative background conditions have been performed for most of the metals associated with acid precipitation. Examples are given here for cadmium and mercury. These overviews are only the beginning stage of relating pollutant releases to environmental effects.
Natural Selection of PAH-Degrading Bacterial Guilds at Coal-Tar Disposal Sites
Authors: William C. Ghiorse, James B. Herrick, Robert L. Sandoli, Eugene L. Madsen
Journal: Environmental Health Perspectives (1995)

Microbial activity patterns at buried coal-tar disposal sites have been under investigation for several years to determine the response of naturally occurring microflora to polycyclic aromatic hydrocarbons (PAHs) at the sites.At one site in upstate New York, data have shown enrichment of PAH- degrading bacteria in subsurface contaminated zones but not in uncontaminated zones.Similar work at a midwestern site showed that the same trends existed in a heterogeneous disposal site except that a borehole outside the plume showed some PAH-mineralization activity.Polymerase chain reaction amplification of DNA extracted from sediment samples from the New York site indicated the presence of naphthalene metabolism genes nahAc and nahR, similar to those found on the NAH7 plasmid of Pseudomonas putida G7.Significant sequence polymorphism was observed in amplified nahAc products, indicating that divergent homologs of nahAc were present in the native community.Protozoan numbers were elevated in sediment samples displaying relatively high PAH-degrading activity, suggesting that a food chain was established based on PAH-degrading bacteria.Removal of the coal-tar source at the site occurred in 1991.In 1992, sampling of three key borehole stations revealed that mixing and backfilling operations had introduced soil microorganisms into the source area and introduced 14C-PAH-mineralization activity into the previously inactive pris- tine area.Thus removal of the source of the contaminants and restoration at the site have altered the microbial activity patterns outside the contami- nant plume as well as in the source area.
What it feels like to be compulsorily detained for treatment
Journal: BMJ (2017)

What it feels like to be compulsorily detained for treatmentTaking a patient's autonomy is life changing.This account shows the importance of careful handling of the situation both before and after the event AnonymousIt was a Bic-the biro-that changed my life.I've wondered since if the doctor using it knew that many years later his signature that day would still have impact.
The EMCDDA annual report 2010: the state of the drugs problem in Europe
Authors: None Editorial team
Journal: Eurosurveillance (2010)

Preview this article: The EMCDDA annual report 2010: the state of the drugs problem in Europe, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/15/46/art19714-en-1.gif
Coffee and Pancreatic Cancer
Authors: Alvan R. Feinstein
Journal: JAMA (1981)

THE RECENT report that coffee may cause pancreatic cancer<sup>1</sup>was presented in a pattern that has become distressingly familiar. The alleged carcinogen is a commonly used product. The report was given widespread publicity before the supporting evidence was available for appraisal by the scientific community, and the public received renewed fear and uncertainty about the cancerous hazards lurking in everyday life. The research on coffee and pancreatic cancer was done with the case-control technique that has regularly been used in epidemiologic circumstances where the more scientifically desirable forms<sup>2</sup>of clinical investigation—a randomized controlled trial or a suitably performed observational cohort study—are either impossible or unfeasible. In case-control studies, the investigators begin at the end, rather than at the beginning, of the cause-effect pathway. The cases are selected from persons in whom the target disease has already developed. The controls are selected from persons in whom that disease has not
Posttraumatic multisystem organ failure
Authors: M. M. DeCamp
Journal: JAMA (1988)

THE SYNDROME of multisystem organ failure (MSOF) currently affects a wide variety of critically ill or injured patients. The mortality rate is well in excess of 60%. Its natural course requires long stays in the intensive care unit and consumes excessive monetary, physician, and hospital resources. The emergence of MSOF is directly related to improvements in organ system support and monitoring, which have made it possible to sustain previously lethal critical illness. The syndrome is characterized by a hyperdynamic, hypermetabolic state identical to that seen in sepsis. The term<i>sepsis syndrome</i>also is used to reflect the fact that infection, although frequently present, is not essential for initiating or perpetuating progressive organ failure. A systemic inflammatory response modulated by a cascade of soluble protein and lipid mediators seems to be the final common pathway linking the sepsis syndrome with MSOF. Herein, we review the origin and presentation of MSOF and
Hepatitis B virus envelope variation after transplantation with and without hepatitis B immune globulin prophylaxis
Authors: W Carman
Journal: Hepatology (1996)

Hepatitis B virus (HBV) replicates via an intermediate RNA step. High frequency of polymerase errors with additional selection pressure leads to mutations in the HBV genome. We investigated the number, type, and antigenic effects of mutations in the coding region of the HBV surface antigen in eight patients who underwent orthotopic liver transplantation (OLT) for HBV-related end-stage liver disease and were experiencing infection of the graft and who received hepatitis B surface antigen antibody (anti-HBs) prophylaxis (hepatitis B immune globulin [HBIG]) after OLT. Controls were chronic HBV patients who underwent kidney transplantation and received the same immunosuppressive regime but no HBIG. The S-gene was amplified from serum before and after transplantation, sequenced, and changes in the genome were analyzed. In the five patients who experienced reinfection while receiving anti-HBs, clear mutations occurred in the S-gene. In the patient who did not receive HBIG and those who experienced reinfection only after termination of HBIG, no mutations were found in the S-gene. In the kidney recipients, mutations in the S-gene occurred in only one of eight patients. Because the a determinant contains neutralizing epitopes, this region was chosen for antibody binding to quantify antigenic effects of the mutations. The two patients who selected mutations in the a determinant and became reinfected while receiving HBIG had reduced antibody binding after OLT. Our results suggest that HBIG after OLT imposes a selection pressure on the S-gene, and that mutations are one mechanism for reinfection while receiving HBIG.
Medical Economics
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal