tbuckley/cabot-search huggingface dataset:
Gastrointestinal bleeding
Authors: I. Gralnek
Journal: Endoscopy (2012)

There were a number of interesting abstracts presented at the 2012 Digestive Disease Week (DDW; 19 – 22 May, San Diego, California, USA) that covered gastrointestinal bleeding and endoscopy. The following abstracts are those that were found to have particular high clinical importance and the potential for direct impact on the endoscopic care of patients.
VAGINAL OÖPHORECTOMY.
Authors: C. P. THOMAS
Journal: JAMA (1895)

It has been very evident to the writer, for the past two years, that celiotomy for the removal of small, cystic, prolapsed, painful or adherent ovaries, or small tubal cysts or pus tubes, even by those who have done the greatest number of these operations, is fast falling into disrepute. Many of our leading gynecologists are curetting, or packing the uterus, or attempting to catheterize the Fallopian tubes, with the vain hope of avoiding the necessity of opening the abdominal cavity for their removal in the usual way. At least two of our latest works on gynecology recommend that curettage be tried for pus tubes, and if that fails, give rest and expectant treatment, with general tonics, and the pus will often disappear by absorption, or through inspissation. The same writer admits, however, that single pus tubes are more dangerous than double ones, owing to the liability to accident should
Generalized cutaneous candidiasis associated with diffuse myopathy and thymoma
Authors: L. F. Montes
Journal: JAMA (1968)

Although the coexistence of thymus disease with candidiasis has been mentioned, the association of generalized cutaneous candidiasis with thymoma has apparently been documented only once before. This report describes such an association in a second patient in whom another thymus-related disease, diffuse myopathy, was also present. Surgical removal of the tumor, a thymoma of the spindle cell variety, did not result in improvement of the myopathy nor of the candidiasis. Cutaneous lesions of candidiasis responded to local anticandida agents, but they relapsed when the therapy was discontinued and showed a tendency to worsen when steroid therapy for the myositis was started. It would appear that thymoma should be added to the list of abnormal general states that may predispose to candidiasis.
Ethics
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nursing, Poetry
Authors: Linda Honan Pellico
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Reaching the readers: experience with the AMA specialty journals
Authors: M D Springer, G D Lundberg, J T Baker, T J Carroll
Journal: JAMA (1990)

The average physician in the United States receives a large number of medical publications each month. Some appear because the physician deliberately bought a subscription. Some are received as a benefit of membership in one or more professional organizations. And some simply arrive in the mail as a result of "controlled circulation," because his or her name is on some list of physicians who share certain practice characteristics deemed desirable by the publisher. Conventional wisdom has held that physicians are more likely to read and value publications they have deliberately purchased. However, some time ago a substantial body of information available to the commercial world began to question that point of view. Syndicated reader research suggested high readership for some publications received on a controlled basis. Sadly, the publications with the highest scores often were not the "worthy" peer-reviewed scientific journals; instead, they were tabloids and specialty magazines that are
A Study of Psychosis in a Pair of Identical Twins
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Temporary Matters
Authors: Dimitri A. Christakis
Journal: JAMA (1997)

Medical students and resident physicians spend much of their training engaged in transient, time-limited relationships with patients, families, and other care providers. This article offers a partial catalog of the problems that the evanescent nature of trainees' relationships with others creates in their lives, the strategies they often use to address these problems, and the deleterious consequences these strategies may have on their behavior and ethical development.
Plasma extravasation in the rat trachea induced by cold air is mediated by tachykinin release from sensory nerves.
Authors: S Yoshihara, B Chan, I Yamawaki, P Geppetti, F L Ricciardolo, P P Massion, J A Nadel
Journal: American Journal of Respiratory and Critical Care Medicine (1995)

Cold air was delivered to anesthetized, artificially ventilated, pathogen-free F344 rats via a tracheal cannula. Inhalation of cold air increased Evans blue dye extravasation in the trachea in a time-dependent (1 to 10 min) manner. Plasma extravasation increased after 3 min exposure to cold air and reached a maximum after 10 min exposure. The neutral endopeptidase inhibitor, phosphoramidon (2.5 mg/kg, intravenously), increased by 84% the plasma extravasation induced by inhalation of cold air for 1 min. The plasma extravasation evoked by 5 min exposure to cold air was abolished by the NK1 tachykinin receptor antagonist, CP-99,994 (4 mg/kg, intravenously); was reduced 30% by the B2 bradykinin receptor antagonist, HOE140 (0.1 mumol/kg, intravenously); and was not affected by H1 (pyrilamine, 10 mg/kg, intraperitoneally) or H2 (cimetidine, 10 mg/kg, intraperitoneally) histamine receptor antagonists or the cyclooxygenase inhibitor indomethacin (5 mg/kg, intravenously). In rats infected with Sendai virus, plasma extravasation evoked by inhalation of cold air was greater than in pathogen-free rats. Pretreatment with CP-99,994 (4 mg/kg, intravenously) inhibited completely the plasma extravasation induced by cold air in virus-infected rats. These findings indicate that cold air increases plasma extravasation in the rat trachea by a neurogenic mechanism that involves the release of tachykinins from sensory nerves. Kinin release may also play a role in this neurogenic inflammatory response.
Die Ueberpflanzung der männlichen Keimdrüse.
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE CAPILLARY PERMEABILITY OF DIFFERENT ORGANS
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 5167: Cell autonomous and non-autonomous actions of CCL22 in oral carcinogenesis
Authors: Li-Wha Wu
Journal: Cancer Research (2019)

Abstract Oral cancer, a subtype of head and neck cancer, has been the 4th leading cause of male cancer death in Taiwan for the past decade. Smoking, alcohol consumption, and betel quid chewing are major risk factors for oral cancer in Taiwan. The crosstalk between immunity and cancer cells can both inhibit and enhance tumor growth and is now classified as a cancer hallmark. The accumulation of regulatory T cells (Tregs) in several tumor types potentially plays a critical role in tumor evasion of immune surveillance. Oral cancer is also characterized by an increase in the number of infiltrating Tregs; however, the significance of the increase on the patient prognosis remains controversial. We found that the expression of CCL22, a chemokine for Treg recruitment, was not only positively with poor prognosis in oral cancer patients but also significantly correlated with that of FOXP3, a master regulator for Treg development and functions, in the same patients. The correlation is also validated in TCGA database analysis of head and neck cancer patients. The depletion of CCL22 expression reduced oral cancer cell proliferation, migration and invasion, suggesting an oncogenic role of CCL22 in oral cancer. Since CCR4 is the receptor for CCL22, we studied the in vitro and in vivo impact of deregulated CCL22-CCR4 signaling axis in oral carcinogenesis. We first confirmed the surface expression of CCR4 in oral cancer cells by flow cytometry. Ectopic CCL22 overexpression increased oral cancer cell migration and invasion without the effect on proliferation. Through injection of CCL22-altered oral cancer cells in both syngeneic and athymic backgrounds, the cell autonomous and non-autonomous actions of CCL22 and the mechanism responsible for the CCL22 deregulation in oral cancer will be discussed. This study will not only further the role of CCL22-CCR4 signaling axis in modulating the crosstalk between oral cancer and its microenvironment but also provide a novel therapeutic strategy for treating oral cancer. Citation Format: Li-Wha Wu. Cell autonomous and non-autonomous actions of CCL22 in oral carcinogenesis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 5167.
SMILE A WHILE
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effects of Di(2-Ethylhexyl) Phthalate on the Gonadal Pathophysiology, Sperm Morphology, and Reproductive Performance of Male Rats
Authors: Deepak K. Agarwal, Scott Eustis, James C. Lamb, Jerry R. Reel, William M. Kluwe
Journal: Environmental Health Perspectives (1986)

Dietary exposure of adult male F344 rats to 0, 320, 1250, 5000, or 20,000 ppm DEHP for 60 consecutive days resulted in a dose-dependent reduction in total body, testis, epididymis, and prostate weights at 5000 and 20,000 ppm.Degenerative changes were observed in testis, along with decreased testicular zinc content, reduced epididymal sperm density and motility, and increased occurrence of abnormal sperm at 20,000 ppm.There was a trend towards reduced testosterone and increased luteinizing hormone and follicle stimulating hormone in serum at 5000 and 20,000 ppm.The mean percentage of fertile animals was unchanged and reduction in fertility parameters, although not marked in severity, were correlated with gonadal effects.Average litter size was reduced at 20,000 ppm, but initial pup weights and growth were unaffected.There were no grossly observed abnormalities in the offspring and the rate of neonatal deaths was similar in control and DEHP treated groups.Characteristic toxicity manifestations of DEHP included dose-dependent en- largement of liver and reduced sperm triglycerides and cholesterol.Additionally, serum albumin and total proteins were dose dependently increased upon treatment with DEHP.Cessation of exposure to DEHP initiated partial to complete recovery from toxicity in most cases.The magnitude of recovery were variable with that ofthe gonads being slower than other systems.These data suggest a lack of reproductive dysfunction in F344 male rats at DEHP doses below 20,000 ppm which produced measurable testicular degeneration and afflicted epididymal sperm morphology under the present experimental conditions.
Boundaries in the physician-patient relationship
Authors: A. Fay
Journal: JAMA (1995)

<h3>In Reply.</h3> —Dr Tauer and Dr Goodwin have misread my Contempo article. I appreciate the opportunity to correct their misreadings. Tauer is correct in saying that research using human embryos produced by in vitro fertilization without transfer to a human uterus was found acceptable from an ethical point of view by the EAB in 1979,<sup>1</sup>but my article did not claim that the Human Embryo Research Panel was the first to approve such research. Rather, it was first "to approve funding for the production of human embryos for research purposes."<sup>2</sup>This is a different matter. The 1994 Human Embryo Research Panel Report states specifically that one of its charges was "to provide advice as to areas that: (1) are acceptable for federal funding." It also states that "[t]he Panel supports funding of certain areas of preimplantation embryo research within the framework of the guidelines specified below."<sup>1</sup> In
AMA Honors Outstanding Men At Scientific Awards Dinner
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Inflammatory bowel disease
Authors: Ella Mozdiak, John O’Malley, Ramesh Arasaradnam
Journal: BMJ (2015)

#### The bottom line A 21 year old woman presented to her general practitioner with tiredness and abdominal discomfort for the past year. She is treated for iron deficiency anaemia (attributed to menorrhagia) and for presumed irritable bowel syndrome. After hospital admission a few months later with suspected appendicitis, tests reveal vitamin B12 deficiency and raised inflammatory markers, prompting gastroenterology referral. Colonoscopy with terminal ileal biopsy confirms a diagnosis of Crohn's disease. Inflammatory bowel disease encompasses ulcerative colitis and Crohn's disease, both idiopathic chronic diseases of the gastrointestinal tract. Ulcerative colitis is characterised by diffuse inflammation affecting the mucosa of the colon only. Crohn's disease involves patchy transmural ulceration that can affect any part of the gastrointestinal tract. Around 5% of patients have features of both subtypes and are labelled inflammatory bowel disease "unclassified."1 #### How common is inflammatory bowel disease?
UICC Postgraduate Courses on Clinical Cancer Chemotherapy
Journal: JNCI Journal of the National Cancer Institute (1983)

Journal Article UICC Postgraduate Courses on Clinical Cancer Chemotherapy Get access JNCI: Journal of the National Cancer Institute, Volume 71, Issue 3, September 1983, Page 649, https://doi.org/10.1093/jnci/71.3.649-d Published: 01 September 1983
THE SIGNIFICANCE OF THE GLYCOGEN REACTION IN THE BLOOD.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal