tbuckley/cabot-search huggingface dataset:
Thanksgiving
Authors: Ted McMahon
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Gonadal Liberation
Authors: Robert S. Sanford
Journal: JAMA (1971)

The privates are becoming more public! Television touts Feminine Hygiene Spray for "that special problem." The female body has now become acceptable matter for open discussion and viewing, even by the most prudish. Public service announcements recommend a Pap smear or suggest that once a month, while bathing, a woman should palpate her breasts as instructed by her physician. But the male body is still taboo. Cancer of the testis and penis, two of the most obvious and deforming of male neoplasms (responsible for up to 3% of all male cancers,<sup>1-4</sup>18% to 20% in an uncircumcized population<sup>5</sup>) and usually attacking those in the prime of life, are never mentioned in public. Can you imagine the public service ad: "Look your penis over by pulling back the foreskin. Feel your testicles once per month to check their size and firmness." These lesions are "picked up" by wives, girl
THE SUPPRESSION OF SYPHILIS.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fatal Cyanide Poisoning: Accidental Ingestion of Amygdalin
Authors: Jonathan H. Tress
Journal: JAMA (1977)

<h3>To the Editor. —</h3> Amygdalin (laetrile) tablets can release hydrocyanic acid on exposure to hydrolytic enzymes. To our knowledge, no fatality due to such poisoning has been reported to date. We wish to draw attention to the fact that when ingested accidentally by young children, amygdalin tablets may constitute a potentially fatal hazard. <h3>Report of a Case.—</h3> An 11-month-old girl accidentally ingested from one to five 500-mg amygdalin tablets. The tablets belonged to the child's father who has a malignant neoplasm. They were thought to be harmless by the parents and were contained in a vial along with an assortment of vitamin tablets. The patient became listless within half an hour after ingestion and vomited. Emesis was induced again by the mother who then rushed the child to the local hospital when her breathing became irregular and her state of consciousness became altered. An hour after ingestion, she was in
Opinions vary, but some recommend hitting certain cancers 'harder and earlier'
Authors: A. Skolnick
Journal: JAMA (1991)

NEW TECHNOLOGIES are making it possible to treat many cancer patients with far more toxic levels of chemotherapy than generally have been used until now. A panel of scientists addressed this sometimes controversial issue in Phoenix, Ariz, at the 33rd American Cancer Society Science Writers' Seminar. With the help of such new techniques, these panelists agreed, cancers now should be hit earlier and a lot harder. Despite the higher chances of longer survival or cure, physicians have been reluctant to use more toxic doses of chemotherapy because of its many adverse effects, especially the life-threatening bleeding and infections that result from destruction of the patient's bone marrow. But now, say the researchers, there are ways to quickly restore or replace the patient's immune system with cell growth factors and with autologous and allogeneic bone marrow transplants. <h3>Antiemetics Available</h3> In addition, there are new agents that can minimize the nausea and
Anticipated Public Health Consequences of Global Climate Change
Authors: Janice Longstreth
Journal: Environmental Health Perspectives (1991)

Human activities are placing enormous pressures on the biosphere. The introduction of new chemicals and the increasing ambient levels of existing chemicals have resulted in atmospheric degradation. This paper reviews some of the adverse effects of stratospheric ozone depletion and global warming. Because the atmospheric effects of ozone depletion are fairly well characterized, quantitative risk estimates have been developed. However, because the atmospheric effects of global warming are less understood, public health problems that could be intensified by climate change are assessed qualitatively. The interactive effects of these two phenomena are also discussed.
Silicosis and Coal Workers' Pneumoconiosis
Authors: Vincent Castranova, Val Vallyathan
Journal: Environmental Health Perspectives (2000)

Exposure to coal mine dust and/or crystalline silica results in pneumoconiosis with initiation and progression of pulmonary fibrosis.This review presents characteristics of simple and complicated coal workers' pneumoconiosis (CWP) as well as pathologic indices of acute and chronic silicosis by summarizing results of in vitro, animal, and human investigations.These results support four basic mechanisms in the etiology of CWP and silicosis: a) direct cytotoxicity of coal dust or silica, resulting in lung cell damage, release of lipases and proteases, and eventual lung scarring; b) activation of oxidant production by pulmonary phagocytes, which overwhelms the antioxidant defenses and leads to lipid peroxidation, protein nitrosation, cell injury, and lung scarring; c) activation of mediator release from alveolar macrophages and epithelial cells, which leads to recruitment of polymorphonuclear leukocytes and macrophages, resulting in the production of proinflammatory cytokines and reactive species and in further lung injury and scarring; o) secretion of growth factors from alveolar macrophages and epithelial cells, stimulating fibroblast proliferation and eventual scarring.Results of in vitro and animal studies provide a basis for proposing these mechanisms for the initiation and progression of pneumoconiosis.Data obtained from exposed workers lend support to these mechanisms.
History of sports medicine in The Netherlands.
Journal: British Journal of Sports Medicine (1989)

The second announcement of the XXIVth FIMS World Congress of Sports Medicine (Amsterdam, May 27- June 1, 1990) refers to Holland as 'the cradle of sports medicine'.Good enough reason to look into the history of sports medicine in the Netherlands!Early years and 'The Federation of Bureaux' Sports medicine has a long history in the Netherlands.As early as 1906 Van den Berg was examining the in- fluence of cycling on the heart.The scientific work of Buytendijk during the Olympic Games in Amsterdam in 1928 is well known.In later years a group around Jongbloed in the 1960s did basic research in the sports medical field.At the time of Buytendijk's work, practising active sport was not so well accepted as nowadays.Physicians, especially, felt that there were high risks for the human being.On the other hand, there were doctors who could not agree with that opinion and said that healthy human beings could not harm their bodies by practising sports.They stressed that a good medical * To create new possibilities for examination and guidance * To introduce nationwide accessible sport medical units * To adapt to the specific needs of sportsmen * To stimulate education and information.
Bisphosphonate Use and Atypical Fractures of the Femoral Shaft
Authors: Madhuri Sopirala, A David, W Leona
Journal: New England Journal of Medicine (2011)

correctionsHe was treated for leprosy with dapsone, clofazimine, and minocycline (for 30 months), with initial progressive sloughing of the leg lesions, leaving ulcerations that healed by secondary intention (Fig. 1C).He remained asymptomatic except for persistent bilateral neuropathic pain in the lower leg that was attributed, in part, to diabetes mellitus.The patient's history of exposure to armadillos years before the development of the acquired immunodeficiency syndrome suggests that HIV-altered cellular immunity probably facilitated subclinical M. leprae infection.With immune reconstitution resulting from highly active antiretroviral therapy, symptomatic borderline tuberculoid leprosy with reversal (type 1) reaction developed in him.Clinicians should consider leprosy in patients receiving treatment for HIV who present with neuralgia, acute edematous, erythematous nodules or tumors, and a history of possible exposure to leprosy, including previous contact with armadillos in the southern United States.
War Wounds
Authors: Edwin J. Pulaski
Journal: New England Journal of Medicine (1953)

THE care of war wounds in these days of conflict and world tension is of vital concern to all in the field of medicine. Accordingly, this communication has been prepared to give a progress report on the current care of the wounded of war. When one views the prospects of full-scale hostilities in the Atomic Age, the enormity and gravity of the situation that confronts all physicians, civilian and military alike, is staggering. It has seemed appropriate that this paper should consider the following subjects: lessons learned in World War II, that have been relearned through experience in the Korean . . .
Women Experience Greater Toxicity With Fluorouracil-Based Chemotherapy for Colorectal Cancer
Authors: Jeff A. Sloan, Richard M. Goldberg, Daniel J. Sargent, Delfino Vargas-Chanes, Suresh Nair, Steven S. Cha, Paul J. Novotny, Michael A. Poon, Michael J. O’Connell, Charles L. Loprinzi
Journal: Journal of Clinical Oncology (2002)

PURPOSE: The toxicity profile of fluorouracil (5-FU)–based chemotherapy given on 5 consecutive days at doses of 370 to 450 mg/m 2 has been well documented. A meta-analysis of six North Central Cancer Treatment Group (NCCTG) cancer control trials involving 786 patients indicated that women treated with this type of regimen experienced more severe stomatitis and leukopenia than men. After these findings, an additional meta-analysis of the toxicity profiles on five NCCTG colorectal cancer treatment trials was undertaken. METHODS: Data for 1,093 women and 1,355 men from 12 different treatment arms were included. The primary end points were the incidence of stomatitis, leukopenia, alopecia, diarrhea, nausea, and vomiting, recorded with standard National Cancer Institute common toxicity criteria. Fisher’s exact test was used to compare incidence and severity across sexes, supplemented by Forrest meta-analysis plots and logistic regression. RESULTS: The incidence of four out of six toxicities studied was significantly greater for women than men; the exceptions were severe nausea and vomiting. Overall, almost half of the women compared with a third of the men experienced severe toxicity (P &lt; .0001). Logistic regression confirmed the univariate findings while adjusting for the effects of study, dose, body mass index, and age. The differences were consistent across treatment cycles. Response rates and survival distributions were the same for both sexes. CONCLUSION: This study confirms an earlier finding that women receiving 5-FU–based chemotherapy in a 5-day bolus schedule experience toxicity more frequently and with more severity than men. These data raise the question of whether the recommended initial dose of 5-FU–based chemotherapy for women should be lower than that for men.
Clinical Hematology and Oncology: 1986
Journal: JNCI Journal of the National Cancer Institute (1985)

Journal Article Clinical Hematology and Oncology: 1986 Get access JNCI: Journal of the National Cancer Institute, Volume 75, Issue 5, November 1985, Page 985, https://doi.org/10.1093/jnci/75.5.985-b Published: 01 November 1985
Presentation of Benzo(a)pyrene to Microsomal Enzymes by Asbestos Fibers in the Salmonella/Mammalian Microsome Mutagenicity Test
Authors: K. Szyba, A. Lange
Journal: Environmental Health Perspectives (1983)

The potential effect of asbestos fibers on mutagenicity of benzo(a)pyrene was investigated by us- ing the Ames test.Asbestos fibers without a coating of benzo(a)pyrene or benzo(a)pyrene when not dissolved in DMSO lacked any mutagenic effect in the Salmonella/mammalian microsome mutagenicity test.However, when benzo(a)pyrene was adsorbed onto asbestos, significant numbers of mutated bacteria were observed.This shows that asbestos fibers can serve a carrier role presenting benzo(a)pyrene to the enzymatic microsomal system, thus enhancing mutagenicity of this compound.
Continuing Competence of Physicians
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE VITA PROPRIA OF CELLS.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Immunity in Syphilis.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Preoperative medication and its effect on blood gases
Authors: J. A. Pierce
Journal: JAMA (1965)

The effect of preoperative medication on blood gases was studied in two groups of patients undergoing open heart surgery using a cardiopulmonary bypass. One group of 16 patients (meperidine group) received meperidine hydrochloride, promethazine hydrochloride, and pentobarbital as premedication; the second group of 16 patients (control group) received pentobarbital only. The meperidine group showed significant reduction in arterial oxygen pressure (Po<sub>2</sub>) after premedication with insignificant changes in arterial carbon dioxide pressure (Pco<sub>2</sub>), and pH. The control group showed no change in Po<sub>2</sub>, Pco<sub>2</sub>, and pH. Thus, narcotics can produce arterial hypoxemia in the premedicated surgical patient in the presence of normal values of pH and Pco<sub>2</sub>before the induction of anesthesia. Narcotics reduce the normal sighing frequency and may depress the reflex urge to maintain normal pulmonary mechanisms. Satisfactory sedation can be attained with barbiturates alone.
Primary Anatomy
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chronic idiopathic bile peritonitis
Authors: R. F. Sanner
Journal: JAMA (1965)

THE PATHOPHYSIOLOGY and secondary effects of acute bile peritonitis have been well investigated and described, but the literature contains a paucity of reference to the effects of prolonged exposure of the tissues to this irritating substance. Leakage of bile usually follows surgery or trauma and occasionally infection; however, cases of socalled idiopathic or spontaneous bile peritonitis are also reported at the rate of several each year, particularly in the foreign literature. We had occasion some months ago to treat a case in which bizarre findings led to investigation and organization of the material in this paper. <h3>Report of a Case</h3> The patient, a 59-year-old Negro man, was admitted to the hospital complaining of soreness of the stomach. He stated that during the previous 31/2 months he had had several episodes of pain in the right lower quadrant of the abdomen, lasting two to three days. He denied trauma, nausea, or
Physical Diagnosis.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Beat
Authors: Erin E. Dooley
Journal: Environmental Health Perspectives (2012)

When the U.S. FDA announced new rules for sunscreen labeling in June 2011, manufacturers were given a year to comply. 1 In May 2012 the agency announced a six-month delay in enforcement to give manufacturers extra time to retool labels and complete broad-spectrum testing for their products. 2Under the new regulations, sunscreen products including cosmetics and moisturizers must back up labeling claims with testing to ensure they deliver the promised amount of protection.Only products with an SPF higher than 15 can claim they reduce risks of skin cancer and early aging, and labels may no longer use the vague and unsubstantiated terms "waterproof" and "sweatproof," but instead must state how long products offer water-resistant protection.