tbuckley/cabot-search huggingface dataset:
Insulin Release May Follow Two-Step Process Involving Blood Sugar at the Liver
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AUTHORS' REPLY
Authors: C. Haslett, S C Donnelly
Journal: Thorax (1992)

Cellular mechanisms of acute lung injury: implications for future treatment in the adult respiratory distress syndrome Although I agree that antibodies to adhesive molecules will have a role in treating the adult respiratory distress syndrome (ARDS), as neutrophil activation by C5a forms the basis of the injury I cannot understand why Drs S C Donnelly and C Haslett (April 1992;47: 260-3) fail to give credit to the overriding importance of endotoxaemia.Since there are so many mechanisms and mediators con- cerned in ARDS, just as there are in Gram negative bacterial shock, there has to be a common trigger-that is, usually, lipopoly- saccharide (cf fig 2).It seems that mistrust has arisen from the results of two sets of experiments conducted by Haslett et al, in particular the one in which a synergistic effect of a small dose of lipopoly- saccharide and C5a was seen.Yet in fact endotoxin itself produces C5a.In my ex- periments conducted in 1970-72 it was clear that endotoxin caused acute lung injury with all the features of ARDS.The details of the mechanisms were reviewed by Brigham and Meyrick' in 1986.In recent years several groups have described endotoxaemia at the onset of ARDS.'4Thus I feel sure that the emphasis will switch to means of combating endotoxaemia.
Brand logo recognition by children aged 3 to 6 years. Mickey Mouse and Old Joe the Camel
Authors: P. M. Fischer
Journal: JAMA (1991)

Objective.\p=m-\Little is known about the influence of advertising on very young children.We, therefore, measured product logo recognition by subjects aged 3 to 6 years.Design.\p=m-\Children were instructed to match logos with one of 12 products pictured on a game board.Twenty-two logos were tested, including those rep- resenting children's products, adult products, and those for two popular cigarette brands (Camel and Marlboro).Setting.\p=m-\Preschools in Augusta and Atlanta, Ga.Participants.\p=m-\Aconvenience sample of 229 children attending preschool.Results.\p=m-\Thechildren demonstrated high rates of logo recognition.When analyzed by product category, the level of recognition of cigarette logos was in- termediate between children's and adult products.The recognition rates of The Disney Channel logo and Old Joe (the cartoon character promoting Camel cigarettes) were highest in their respective product categories.Recognition rates increased with age.Approximately 30% of 3-year-old children correctly matched Old Joe with a picture of a cigarette compared with 91.3% of 6-year-old children.Conclusion.\p=m-\Veryyoung children see, understand, and remember adver- tising.Given the serious health consequences of smoking, the exposure of chil- dren to environmental tobacco advertising may represent an important health risk and should be studied further.(JAMA.
Holistic Medicine
Authors: Robert D. Gillette
Journal: JAMA (1979)

<h3>To the Editor.—</h3> The editorial "Holistic Health or Holistic Hoax?" by John P. Callan, MD (241:1156, 1979), led me to pick up a book on the subject at a local store. I found the tome to be a hodgepodge of nonscience. The concern expressed in the editorial is well founded. It would be a mistake, though, to throw the baby out with the bath-water. There is still the pressing need to balance the scientific and technical accomplishments of US medicine with health care that recognizes people as more than collections of organ systems. Although the concept of integrating body and mind has been carried to ridiculous extremes, it is basically sound. Unfortunately, the word "holistic" has been so misused that we may now have to abandon it.
The Year Book of Treatment for 1893.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Frequency of the echocardiographic embolic risk markers in paroxysmal atrial tachycardia compared with permanent atrial fibrillation? Implication for anticoagulant treatment Lydia Djaouti, Charles Smadja, Fabrice Carrat, Catherine Albo, Bulent Buyukoglu, Arial A. Cohen. Saint Antoine University Hospital, Paris, France
Journal: Journal of the American College of Cardiology (2001)
From the PHLS. Virus meningitis and encephalitis 1978-82.
Journal: BMJ (1985)

MEDICAL TREATMENTThis can be with 3 adrenoceptor blocking drugs and antithyroid drugs such as carbimazole, methimazole, propylthiouracil.It would be appropriate in Graves' disease, in which remission occurs in about half the cases, but it is not recommended in toxic adenoma, in which thyrotoxicosis invariably recurs once the treatment has been stopped.The use of c blockers is mainly for symptomatic relief.An advantage of this treatment is that it does not interfere with thyroid function tests.It is useful in those conditions in which thyrotoxi- cosis is transient-for example, silent thyroiditis, for which antithyroid drugs and ablative treatment would be inappropriate.Drugs like propranolol are used as adjuncts to antithyroid drugs or iodine-131 treatment.Its use as sole preparation in patients undergoing thyroid surgery is not widely accepted and may be risky outside centres where this is done routinely and the necessary precautions are taken.Antithyroid drugs are given for 12-18 months.This form of treatment may be preferred in children and young adults, especially if the goitre is not large and the disease is not severe.Relapse occurs in over 50% of cases after a full course.Patients should be told this and be informed of possible adverse effects.In the event of relapse further courses of antithyroid drugs, surgery, or treatment with iodine-131 may be chosen, though ablative treatments are prefer-
Hypertension Control and Cardiovascular Outcomes Among Patients With Diabetes and Coronary Artery Disease—Reply
Authors: Rhonda M. Cooper-DeHoff, Yan Gong, Carl J. Pepine
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2022 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical Student Burnout and Professionalism
Authors: Jonathan A. Ripp
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The pseudolymphogram
Authors: G. P. Wegner
Journal: JAMA (1967)

Large bowel carcinoma metastatic to periaortic lymph nodes mimicked roentgenographically the appearance of retained contrast medium following lymphography in two cases. Lymphography in both patients, however, demonstrated complete metastatic tumor replacement of these nodes, with calcification. Of 368 consecutive patients with proved large bowel adenocarcinoma, six or 1.6% showed periaortic nodal calcification. We reviewed various opinions regarding the stimulus to calcification in intestinal neoplasms.
Guidelines for basic life support. European Resuscitation Council Basic Life Support Working Group.
Authors: A Handley
Journal: BMJ (1993)

A basic life support working group of the European Resuscitation Council was set up in 1991. It was given the objective of producing agreed standards of basic life support to ensure uniform teaching of the techniques to health care professionals and lay people throughout Europe. A common complaint in the past, particularly from members of the public who have received instruction in basic life support, is that different organisations teach different techniques. This problem exists within countries as well as among countries. The European Resuscitation Council presents below its basic life support guidelines, which it hopes will be detailed enough to avoid any ambiguities and to be acceptable for use in all the countries represented by the council.
Methylphenidate hallucinosis
Authors: A. R. Lucas
Journal: JAMA (1971)

Methylphenidate hydrochloride caused adverse behavioral reactions in three patients. In two instances, a 6 1/2-year-old girl and a 10-year-old boy were receiving therapeutic dosages for hyperkinetic behavior. In the girl, a state of excitement occurred, followed by catatonic withdrawal, while the most prominent feature in the boy was hallucinosis. The third reaction, also hallucinosis, occurred in a 15-year-old girl who had taken an excess of medication. These reactions highlight the importance of close medical supervision of children receiving even relatively safe psychoactive drugs.
Epithelial Migration Over the Tympanic Membrane and External Auditory Canal
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Does postoperative irradiation improve survival in lung cancer?
Authors: E. Sherrah-Davies
Journal: JAMA (1966)

The treatment of carcinoma of the lung is unrewarding, because the majority of cases, when first seen, are too advanced for anything more than palliative treatment to be possible. An overall fiveyear cure rate of the order of 3% is realistic, and surgery, which holds undisputed priority as the treatment of choice for the apparently "early" case, fails to cure once the disease has spread beyond surgically removable tissues. Most surgeons remove obvious mediastinal glands, and some attempt a routine "radical" mediastinal dissection, but a true block-dissection, as done for cervical nodes, is impossible for anatomical reasons, and once mediastinal nodes are involved, survival rates drop sharply. It is reasonable to suggest, therefore, that postoperative radiation to the mediastinum may help to improve survival rates by dealing with local cancer which is inaccessible to the knife. Theorizing about this, however, does not invite optimism. First, it is well-known that a
Water Content of Aluminum, Dialysis Dementia, and Osteomalacia
Authors: Michael R. Wills, John Savory
Journal: Environmental Health Perspectives (1985)

In the presence of normal renal function, a high concentration of aluminum in drinking water has been implicated as a factor in the etiology of a neurological syndrome in one specific geographical area. The role of aluminum as a toxic agent in other neurological disorders, where renal function is normal, is controversial. Aluminum is absorbed from the gastrointestinal tract and is normally excreted by the kidneys in the urine. In patients with chronic renal failure, aluminum appears to be of proven toxicological importance. In these patients the accumulation of aluminum in tissues causes an encephalopathy (dialysis encephalopathy or dialysis dementia), a specific form of metabolic bone disease (osteomalacic dialysis osteodystrophy), and an anemia and also plays an etiological role in some of the other complications associated with end-stage chronic renal disease. A failure in the normal renal excretory mechanism accounts for the tissue accumulation in chronic renal failure. The majority of chronic renal failure patients who develop aluminum toxicity are on long-term treatment with either hemo- or peritoneal dialysis; some patients develop toxicity who are only on treatment with aluminum-containing phosphate-binding agents. Aluminum in the dialysate appears to be the major source of the metal in chronic renal failure patients who develop aluminum toxicity. The aluminum content of the dialysate depends primarily on the content of the water with which it is prepared; there may be some contribution from the chemicals used in the concentrate which is added to the water. Some domestic tap-water supplies contain aluminum in high concentration, either naturally or because aluminum has been added as a flocculant in the purification process.(ABSTRACT TRUNCATED AT 250 WORDS)
INDEX MEDICUS.
Journal: JAMA (1883)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
<i>Circulation: Heart Failure</i> Editors' Picks
Journal: Circulation (2011)

The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals during the last two years. The studies included in this article represent the “Editors' Picks” for each issue of Circulation: Heart Failure published in 2009 and 2010.
Coronary bypass surgery for unstable angina pectoris. Long-term survival and function
Authors: J. S. Schroeder
Journal: JAMA (1977)

The first 81 patients to undergo coronary artery bypass surgery for unstable angina pectoris at Stanford Hospital have been observed for a mean of 40.8 months. Surgical mortality was 8.5%, and perioperative incidence of myocardial infarction was 16%. The mean 18-month follow-up showed two early cardiac deaths and 12 additional myocardial infarctions. Sixty-seven percent of the patients were angina-free, and the condition of none was worse. After a mean of 40.8 months, two late cardiac deaths and two myocardial infarctions had occurred. Complete relief of angina was present in 51%; 22% had unstable or worsening angina. The probability of survival from time of operation to four months after surgery was 88.8%±3.5%, and this remained unchanged until the two late deaths, which decreased survival probability to 83.8%±4.8% at 43 months. The two late cardiac deaths and the 22% incidence of patients with worsening angina may reflect progression of the atherosclerotic process, late graft occlusion, or both. (<i>JAMA</i>237:2609-2612, 1977)
Fatal Asthma
Authors: Solomon R. Benatar
Journal: New England Journal of Medicine (1986)

ASTHMA has been recognized for more than 30 centuries,1 but only in the past 50 years has death from the disease attracted much attention. Floyer reported sudden death from asthma in an 18-month-old child in 1698.2 In 1784, Cullen wrote, "The asthma, though often threatening immediate death, seldom occasions it, and many persons have lived long under this disease. In many cases, however, it does prove fatal; sometimes very quickly and perhaps always at length."3 In contrast, Laennec, who made many observations on asthma, including the occurrence of nocturnal attacks, did not recognize that it could be fatal. At the . . .
APC of Breast Diseases: Breast Cancer - Epidemiology, risk factors, and Genetics
Authors: K M McPherson, C M Steel, J M Dixon
Journal: BMJ (1994)

Computer enhanced mammogram of a breast cancer.With 570 000 new cases in the world each year, breast cancer remains the commonest malignancy in women and comprises 18% of all female cancers.The incidence among women aged 50 approaches two per 1000 women per year, and the disease is the single commonest cause of death among women aged 40-50, accounting for about a fifth of all deaths in this age group.In the United Kingdom, where the age standardised incidence and mortality is the highest in the world, there are more than 15 000 deaths each year, and the incidence is increasing slowly, particularly among elderly women, by about 1-2% a year.Of every 1000 women aged 50, two will recently have had breast cancer diagnosed and about 15 will have had a diagnosis made before the age of 50, giving a prevalence of breast cancer of nearly 2%.Standardised mortality for breast cancer in different countries.
TRAUMATIC RUPTURE OF THE ABDOMINAL VISCERA WITHOUT EXTERNAL SIGNS OF INJURY.
Authors: DANIEL N. EISENDRATH
Journal: JAMA (1902)

<h3>PROGNOSIS.</h3> Until 1890, when laparotomy first was systematically employed as a means of treatment in this class of injuries, the mortality was a very high one. In 1887 Edler collected 96 cases (uncomplicated) of rupture of the liver, of which 21, or 21.8 per cent., recovered and 75, or 78 per cent., died. Of rupture of the spleen (uncomplicated) only 8 recovered spontaneously, or 15.8 per cent., and 44, or 84.6 per cent., died. Of ruptures of the kidney (uncomplicated) there were 55 cases, of which 36, or 65 per cent., recovered and 19, or 35 per cent., died. Since laparotomy was not performed in any case the recoveries must be regarded as spontaneous ones. In 1896 Petry collected 160 ruptures of the intestine, of which 149, or 93 per cent., died and 11, or 7 per cent., recovered. He also collected 23 perforations of the stomach due to subcutaneous