tbuckley/cabot-search huggingface dataset:
Cytological Aspects of Basal Cell Carcinoma
Journal: JAMA (1963)

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Outcome of Adult AML at First Relapse Following a Risk-Oriented Strategy: An Update of the Northern Italy Leukemia Group (NILG) Experience
Authors: Irene Cavattoni, Enrico Morello, Elena Oldani, Tamara Intermesoli, Ernesta Audisio, Claudia Minotto, Elisabetta Terruzzi, Filippo Marmont, Enrico Maria Pogliani, Giuseppe Rossi, Erika Borlenghi, Alessandro Rambaldi, Sergio Cortelazzo, Renato Bassan
Journal: Blood (2008)
THE LADY DOCTOR FROM GENEVA
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A Newly Recognized Strain of Staphylococcus Aureus Associated with Epidemics in Six Hospitals
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mutations Induced in the Hypoxanthine Phosphoribosyl Transferase Gene by Three Urban Air Pollutants: Acetaldehyde, Benzo[a]pyrene Diolepoxide, and Ethylene Oxide
Authors: Bo Lambert, Bjorn Andersson, Tatiana Bastlova, Sai-Mei Hou, Dennis Hellgren, Ada Kolman
Journal: Environmental Health Perspectives (1994)

Provisional mutational spectra at the hypoxanthine phosphoribosyl transferase (HPRT) locus in vitro have been worked out for acetaldehyde (AA) and benzo[alpyrene diolepoxide (BPDE) in human (T)-lymphocytes and for ethylene oxide (EtO) in human diploid fibroblasts using Southern blotting and polymerase chain reaction (PCR)-based DNA sequencing techniques.The results indicate that large genomic deletions are the predominating hprt mutations caused by AA and EO, whereas BPDE induces point mutations that are mainly GC>TA transversions.The mutational spectra induced by the three agents are clearly different from the background spectrum in human T-cells.Thus, the hprt locus is a useful target for the study of chemical-specific mutational events that may help identify causes of background mutation in human cells in vivo.-
OSLO
Journal: JAMA (1949)

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Mechanical Ventilation in Critically Ill Patients With 2009 Influenza A(H1N1)—Reply
Authors: Clare Ramsey
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE ROLE OF MATRIX METALLOPROTEINASES AND TISSUE INHIBITORS OF METALLOPROTEINASES IN DUCHENNE MUSCULAR DYSTROPHY CARDIOMYOPATHY
Authors: Jonathan Soslow, Meng Xu, James C. Slaughter, Kimberly Crum, W. Bryan Burnette, Yan Ru Su, Kelsey Tomasek, David Parra, Larry Markham
Journal: Journal of the American College of Cardiology (2018)
Factors associated with delayed time to adjuvant chemotherapy (AC) in stage III colon cancer: British Columbia Cancer Agency (BCCA) cohort experience.
Authors: Angela Chan, Ryan Woods, Sharlene Gill
Journal: Journal of Clinical Oncology (2012)

574 Background: The current standard for resected stage 3 colon cancer after surgical resection is adjuvant 5FU-based chemotherapy. In trials, AC is mandated within 8 weeks after surgery, but outside the trial setting, up to 19% of patients do not receive treatment within 8 weeks. A recent meta-analysis confirms that AC started more than 8 weeks after surgery results in significantly decreased overall survival. Our objective was to ascertain logistical and patient factors associated with delayed AC delivery (defined as &gt;56 days from surgery) in referred patients with resected stage 3 colon cancer. Methods: A population-based cohort of patients diagnosed with stage 3 colon cancer between January 2008 to December 2009 referred to the BCCA and treated with at least one cycle of AC were identified. Patient characteristics, and time intervals between surgery, referral, medical oncology consultation (MOC) and AC were assessed. Differences in patient characteristics and time intervals between patients were assessed using the Chi-square and Wilcoxon Rank-sum tests. Results: Median time from surgery to AC was 58 days with 54% of patients receiving AC beyond 56 days. Temporal differences were identified in all intervals between the between the timely and delayed groups (see table 1). Referral was most commonly initiated after hospital discharge. The only patient factors associated with delayed initiation included poorer ECOG status and being treated at the most urban centre within BCCA. Age, gender, comorbidity index, T stage and tumour location were not different between the groups. Conclusions: 54% of patients with stage 3 colon cancer had a delayed AC initiation. Process related delays at each step of the referral process need to be addressed including timely referral, MOC triage and addressing chemotherapy waitlists. [Table: see text]
Familial sea-blue histiocytes with acid phosphatemia. A syndrome resembling Gaucher disease: the Lewis variant
Authors: R. M. Blankenship
Journal: JAMA (1973)

Three siblings with splenomegaly, peripheral neuropathy, café au lait spots, and elevated serum acid phosphatase level also had multiple sea-blue histiocytes apparent on bone marrow examination. Elevated bone marrow acid phosphatase level and abnormal histiocytes were found in the father. There is a relationship of this new syndrome to other conditions associated with sea-blue histiocytes.
The influence of Osler on his students
Authors: E. F. Nation
Journal: JAMA (1969)

Dr. Charles N. B. Camac, a former Osler resident, wrote Lady Osler, May 9, 1913, as follows: My dear Mrs. Chief, In 1905 when I was in Oxford the Chief and I planted some seeds which have yielded fruit; just how much this has been is hard to estimate. That many hungry souls have been fed by this fruit is attested to by the letters &amp; expressions I get every year. Besides this soul feeding success the planting has yielded practical returns. I have waited till these took on some proportions &amp; while these are yet modest I want you &amp; The Chief to have them. If you know of some book he wants and something you would like to get for yourself with this little figure will you please be the Middleman and turn the trick. Affectionately yours, C.N.B. Camac Accompanying this letter was a memorandum of exchange from
Revue du Praticien, Paris
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hyperactive Children
Authors: Becky Bond
Journal: JAMA (1978)

INVARIABLY, when Bobby Smith arrives in the pediatric clinic, there is wailing and gnashing of teeth, followed by the frantic scurrying of staff members into the relative safety of their offices. So great are Bobby's clamorings and his mother's multidecibel response that a staff member once joked that we needed an exorcist on the staff, not another pediatrician. Having dealt with Mrs Smith's difficulties in managing her son's behavior for several months, we were not surprised by her recent announcement, "I have been reading the papers. Bobby is hyperactive and I want medication for it." A thorough exploration of Bobby's symptoms and environment failed to confirm her diagnosis. Nevertheless, Bobby's case illustrates the confusion that surrounds the hyperkinetic syndrome and the complexities of its manifestations and diagnosis. As hyperactivity has gained notoriety in the press, it has come to rival teething as today's scapegoat for anything from tremors to tantrums.
INDUSTRIAL HYGIENE AND THE INTERNATIONAL CONGRESS
Journal: JAMA (2012)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diabetes and the gut.
Journal: BMJ (1979)

Diabetes and the gutDiabetes may affect the function of the gut at every level.Any oesophageal dysfunction, though clinical manifestations are rare in diabetics, can be detected as motor abnormalities, such as weak peristalsis, tertiary contractions, and lower sphincter reflux, by manometry or cineradiography.' These changes appear to be the result of preganglionic parasympathetic damage where there may be axonal degeneration and myelin sheath destruction.Symptoms such as heartburn may be relieved by aluminium hydroxide and dysphagia improved with metoclopramide.Motor dysfunction of the stomach is usually asymptomatic despite dilatation and delayed emptying-"gastroparesis diabeticorum."Test meals (though they have drawbacks) show delayed emptying6 with symptoms of stasis; but even in asymptomatic patients both liquid and solid food may empty simultaneously, in contrast to the normal pattern whereby solid food leaves more slowly.In the past these changes have been assumed to be due to "autovagotomy," but they are not reproduced in non-diabetics by surgical vagotomy.When symptoms do occur anorexia, nausea, and vomiting, or a persistent fullness after meals, usually develop insidiously; but they may arise acutely in diabetic ketoacidosis.Though many diabetics do not have alimentary symptoms, among those who do one important effect may be poor control, attributable to the irregular emptying of food into the intestine.7Surgical drainage procedures have been without benefit.8Regular small meals and painstakingly careful control may help in the short term but have practical limitations.Treatment with metoclo- pramide before meals' has given promising results, however,
America's Nutrition Primer: What to Eat and Why
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation
Authors: Natalia Martinez-Soria, Lynsey McKenzie, Julia Draper, Anetta Ptasinska, Hasan Issa, Sandeep Potluri, Helen J. Blair, Anna Pickin, Asmida Isa, Paulynn Suyin Chin, Ricky Tirtakusuma, Daniel Coleman, Sirintra Nakjang, Salam Assi, Victoria Forster, Mojgan Reza, Ed Law, Philip Berry, Dorothee Mueller, Cameron Osborne, Alex Elder, Simon N. Bomken, Deepali Pal, James M. Allan, Gareth J. Veal, Peter N. Cockerill, Christian Wichmann, Josef Vormoor, Georges Lacaud, Constanze Bonifer, Olaf Heidenreich
Journal: Cancer Cell (2019)

(Cancer Cell 34, 626–642.e1–e8; October 8, 2018) During the preparation of the manuscript, we inadvertently left out Dr. Cameron Osborne, who was an important contributor to the chromatin capture experiments described in our article. His contribution is now included in the Author Contributions section, and his name has been added to the author list in the article online. The authors apologize for the omission. The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic TransformationMartinez-Soria et al.Cancer CellOctober 08, 2018In BriefUsing in vitro and in vivo screens to identify essential RUNX1/ETO transcriptional targets in AML, Martinez-Soria identify CCND2 as required for leukemia maintenance and self-renewal. Targeting this dependency using the CDK4/6 inhibitor palbociclib prolongs the survival of AML PDX models. Full-Text PDF Open Access
DIPHTHERIA AS A COMPLICATION OF SCARLET FEVER.
Journal: JAMA (1902)

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ESGE Newsletter
Journal: Endoscopy (2012)

Dear Endoscopy readers and ESGE members, it is a great honor for me to have been appointed President of the European Society of Gastrointestinal Endoscopy during the UEGW in my hometown. ESGE has become a much more productive society over the past decade and the cooperation with the journal Endoscopy has flourished from this increased activity. ESGE has been more active on many levels. The educational efforts as well as the production of a number of important guidelines are possibly the two most visible endeavours. ESGE guidelines are always published in our official journal Endoscopy and are available with free access on line. Through the guidelines and our educational efforts, we hope to improve the quality of endoscopy in greater Europe. My personal challenge for the coming two years is to further the growth and development of the society. Undoubtedly the new ESGE governing board will play a significant role in this respect. Please go to www.esge.com to read more and become active within ESGE committees.
BODY BUILD AND METABOLISM
Journal: JAMA (1934)

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