tbuckley/cabot-search huggingface dataset:
Taking Leave
Authors: Justin Richardson
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Growth of the Mast-Cell Tumor P. 815 in Thymectomized Mice
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Methodik der Blutuntersuchung, mit einem Anhang: Zytodiagnostische Technik.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Multistate Outbreak of Human &lt;emph type="ital"&gt;Salmonella&lt;/emph&gt; Infections Associated With Exposure to Turtles—United States, 2007-2008
Journal: JAMA (2008)

Turtles and other reptiles have long been recognized as a source of human Salmonella infections. To prevent turtle-associated Salmonella infections in humans, the sale and distribution of small turtles (i.e., those with a carapace length of less than 4 inches) has been prohibited in the United States since 1975. Despite this prohibition, small turtles remain available to the public from various sources, including pet shops, flea markets, street vendors, and Internet websites. In October 2007, the North Carolina Division of Public Health (NCDPH) notified CDC of human infections caused by Salmonella serotype Paratyphi B L (+) tartrate (+) (Salmonella Paratyphi B var. Java) in several states. Salmonella Paratyphi B var. Java is a nontyphoidal strain of Salmonella that causes gastroenteritis. This report describes the results of the epidemiologic and laboratory investigation conducted by CDC and state and local health departments during October 2007-January 2008. The findings document an ongoing, multistate outbreak of Salmonella Paratyphi B var. Java infections, with the first reported illness onset occurring on May 4, 2007. Many of these infections have occurred in young children and have been associated with exposure to small turtles. Prohibiting the sale and distribution of small turtles likely remains the most effective public health action to prevent turtle-associated salmonellosis.
POOLED ANALYSIS OF LONG–TERM SAFETY DATA FROM THE RESOLUTE CLINICAL TRIAL PROGRAM
Authors: Ganesh Manoharan, Franz–Josef Neumann, Stephan Windecker, Martin Leon, Ian Meredith, Shigeru Saito, Patrick Serruys, Sigmund Silber, Alan Yeung, Jorge Belardi, Petr Widimsky, Laura Mauri
Journal: Journal of the American College of Cardiology (2013)
"Status Lymphaticus"
Authors: H. B. Dodwell
Journal: BMJ (1954)

CORRESPONDENCE--unless, of course, one is to fly to the blood bank and demand blood at once, thus increasing the risk of incom- patibility.Dr. Barnard's fears seem to be based mainly on work in vitro.I agree that when dextran is mixed with blood in the test-tube many peculiar things happen: but if dextran is mixed with the blood remaining in an exsanguinated patient the patient gets better.I have never done " dextran compatibility tests " and I do not intend to start until it is shown that they would serve a useful purpose; nor do I propose to allow Dr. Barnard's largely theoretical fears to overwhelm my practical experience, which is that patients who have had a sud- den severe haemorrhage can usually be revived by dextran infusion, and that in such circumstances dextran is safer than plasma or whole blood.-Iam, etc.,
Sanitary and Statistical Report of the Surgeon-General of the Navy for the Year 1881.
Authors: None W. L.
Journal: JAMA (1883)

This, the annual report of Surgeon-General Wales, is a bulky octavo of 684 pages. In his introductory remarks, he calls attention to the fact that a laboratory has been established for original work, and that a museum and library have been founded. The library already contains nearly four thousand volumes. The want of proper appropriations for the hospitals and other branches of the service is justly deplored; in several instances about one-half the amount required being appropriated. The valuable services rendered by the hospital branch are well shown in the summing up by figures—giving 14,013 cases as the total number treated during the year. An interesting table is given referring to the examination of recruits, of whom 8,807 presented themselves, and of these 2,750 were rejected, or 31 per cent. The causes of rejection are tabulated, and the largest number, 661, is from defective development; next to this come diseases
The Cover
Authors: D. Scott Atkinson
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
IMMUNIZATION AGAINST SURGICAL INFECTION.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mayo Clinic Proceedings, Rochester, Minn
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Outcome Of Patients With Myelodysplastic Syndrome (MDS) With Bone Marrow Blasts Between 10-30% Treated With Hypomethylating Agents Versus Intensive Chemotherapy
Authors: Aziz Nazha, Hagop M. Kantarjian, Elias Jabbour, Courtney D. DiNardo, Gautam Borthakur, Naval G. Daver, Stefan H. Faderl, Jing Ning, Wei Qiao, Farhad Ravandi, Tapan M. Kadia, Sherry R. Pierce, Jorge E. Cortes, Guillermo Garcia-Manero
Journal: Blood (2013)
Theophylline
Authors: RICHARD E. KANNER
Journal: Annals of Internal Medicine (1975)

Comments and Correction1 October 1975TheophyllineRICHARD E. KANNER, M.D., F.A.C.P.RICHARD E. KANNER, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-83-4-579_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Zwillich and co-workers presented an interesting paper on theophylline-induced seizures in the June 1975 issue (Ann Intern Med83:784-787). I wonder if they obtained arterial blood gases either just prior to, or during the seizure in any of their patients. I know the authors are well aware that theophylline can be a respiratory stimulant (1) and that respiratory alkalosis can cause seizures (2). Could theophylline, at the high levels noted in their patients, be such a marked respiratory stimulant as to lead to severe alkalosis and seizures? If this is the explanation, it obviously would affect the...References1. RITCHIE J: Central nervous system stimulants, in The Pharmacological Basis of Therapeutics, edited by GOODMAN LS, GILMAN A. New York, The Macmillan Co., 1965, p. 355 Google Scholar2. ROTHERAMSAFARROBIN EPE: CNS disorder during mechanical ventilation in chronic pulmonary disease. JAMA 189:993-996, 1964 CrossrefMedlineGoogle Scholar1. ZWILLICHPIERSONCREAGH CDC: Complications of assisted ventilation. A prospective study of 354 consecutive episodes. Am J Med 57:161-170, 1974 CrossrefMedlineGoogle Scholar2. BREIVIKGRENVIKMILLEN HAE: Normalizing low arterial CO2 tension during mechanical ventilation. Chest 63:525-531, 1973 CrossrefMedlineGoogle Scholar1. ZWILLICHSUTTONNEFF CFT: Theophylline-induced seizures in adults. Ann Intern Med 82:784-787, 1975 LinkGoogle Scholar2. FRANKLIN W: Treatment of severe asthma. N Engl J Med 290:1469-1472, 1974 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: RICHARD E. KANNER, M.D., F.A.C.P.Affiliations: Pulmonary Disease Division The University of Utah Medical Center Salt Lake City, Utah 84132 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 October 1975Volume 83, Issue 4Page: 579-580KeywordsBloodEpileptic seizures ePublished: 1 December 2008 Issue Published: 1 October 1975 PDF downloadLoading ...
Chemical Toxicity of Red Cells
Authors: Sergio Piomelli
Journal: Environmental Health Perspectives (1981)

Exposure to toxic chemicals may result in alterations of red cell function. In certain cases, the toxic effect requires a genetic predisposition and thus affects only a restricted number of individuals; in other instances, the toxic effect is exerted on the hematopoietic system of every person. Glucose-6-phosphate dehydrogenase deficiency is probably the most widespread genetic disorder. It is observed at highest frequency in populations from subtropical countries as a result of its selective advantage vis à vis falciparum malaria. The gene controlling this enzyme is located on the X-chromosome; thus, the defect is sex-linked. Individuals with a genetic defect of this enzyme are extremely susceptible to hemolysis, when exposed to oxidant drugs (such as certain antimalarials and sulfonamides) because of the inability of their red cells to regenerate NADPH. Lead poisoning result in profound effects on the process of heme synthesis. Among the steps most sensitive to lead toxicity are the enzyme delta-aminolevulinic acid dehydratase and the intramitochondrial step that leads to the incorporation of iron into protoporphyrin. By these mechanisms, in severe lead intoxication there is an accumulation of large amounts of delta-aminolevulinic acid (a compound with inherent neurotoxicity), and there are abnormalities of mitochondrial function in all cells of the body. Individuals living in an industrialized society are unavoidably exposed to some environmental lead. Recent evidence indicates that, even at levels of exposure which do not increase the blood lead level above values presently considered normal, abnormalities of heme synthesis are clearly detectable.
Observations on Serum B-12 and Folate Activity in Normal and Leukemic Rats
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ABC of Spinal Cord Injury: at the accident
Authors: A. Swain, D. Grundy, J. Russell
Journal: BMJ (1986)

Spinal cord injury is a mortal condition and has been recognised as such .b^t-i-v.vr.$ ~since antiquity.In about 2500 BC, in the Edwin Smith papyrus, an unknown Egyptian physician accurately described the clinical features of traumatic ;TtIV'egiM, 4~wj~t etraplegia and revealed an awareness of the awful prognosis with the 8 w ¢ t W'A#|;+r AM chilling advice: "an ailment not to be treated."This view prevailed until the tpr ^;= n 4IsJ8.early years of this century.In the first world war 90% ofpatients suffering a spinal cord injury died within one year of wounding and only about 1%-1V -
International Medical Education
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Long-term effect of nadolol or nadolol plus isosorbide-5-mononitrate on renal function and ascites formation in patients with cirrhosis*1, *2
Authors: C MERKEL
Journal: Hepatology (1995)

The association beta-blockers plus nitrates has been reported to impair renal function and renal sodium handling, leading to increased risk of development of ascites, or worsening of a preexisting ascites, or increase in the requirements of diuretic agents. In 81 patients with cirrhosis and esophageal varices, participating in a multicenter controlled clinical trial of prophylaxis of variceal bleeding comparing nadolol (NAD) plus isosorbide-5-mononitrate (I5M) with NAD alone, renal function, presence of ascites, and diuretic requirements were assessed at inclusion and after 6 months of follow-up. No significant variation in s-urea or s-creatinine was observed in either group. Three patients in the nadolol group and two in the NAD plus I5M developed ascites at 6 months (P = .70), and a need to increase diuretic regimen was observed in four and three patients, respectively (P = .76). Decrease in heart rate and in mean arterial pressure was similar in the two groups. There was a significant correlation between increase in s-creatinine and decrease in mean arterial pressure in the whole series (P = .015). Only in patients treated with the association was there a significant larger proportion of patients ascitic who became anascitic, than of patients anascitic who became ascitic (P = .03). In patients treated with the association, there was a significantly larger decrease in hepatic venous pressure gradient (P = .05). It is concluded that patients treated with the association NAD plus I5M are not at increased risk of developing renal dysfunction or worsening of ascites compared with patients treated with NAD alone. Therefore, the presence of ascites should not be considered a contraindication to the use of this association in patients with cirrhosis and portal hypertension.
Marijuana. Does it have a possible therapeutic use?
Authors: S. Cohen
Journal: JAMA (1978)

MENTION marijuana and you will evoke a range of reactions to match every color of the spectrum. Still, such impassioned arguments are no reason to ignore possible therapeutic uses; I address the current status of these studies. Humans and<i>Cannabis sativa</i>have coexisted for millenniums. The stems of the plant served as a source of hemp fiber for rope, canvas, clothing, and paper. The seeds provided oil for food and are still found in packages of mixed birdseed (sterilized, of course). The leaves and flowering tops have been used by many primitive societies as a folk medicine for a wide variety of ailments. Every human complaint has been treated with Indian hemp at one time or another, and certain uses were clearly inappropriate. On the other hand, recent careful investigations have substantiated the effectiveness of a few ancient therapeutic applications of the plant. Pain, whether from toothache, dysmenorrhea, or rheumatism,
P1.01-51 Real world Experience of Pembrolizumab in Patients with Metastatic Nonsmall Cell Lung Cancer (mNSCLC)
Authors: D. Ksienski, E. Wai, M. Lesperance, N. Croteau, L. Fiorino, Z. Poonja, D. Fenton, G. Geller, E. Brooks, D. Glick
Journal: Journal of Thoracic Oncology (2018)
Abdominal pain, intermittent hydronephrosis, and accessory renal vessels
Authors: A. F. Lalli
Journal: JAMA (1967)

THE DIFFERENTIAL diagnosis of the patient with vague upper abdominal pain apparently arising in the right upper quadrant includes the standard considerations such as cholecystitis, ulcer disease, and functional bowel distress. This last diagnosis was made in several of the patients whose cases are reported here and who later proved to have intermittent hydronephrosis caused by accessory renal vessels. Unless specific questions are put regarding the periodicity of the pain and its relationship to maintained positions of the body and/or the ingestion of large quantities of fluid, the correct diagnosis may not be suspected. When the diagnosis is considered and an excretory urogram is performed in the absence of the pain, the hydronephrosis may not be demonstrated.<sup>1,2</sup>The necessity of performing the urogram during an attack of pain is emphasized herein. The data on nine young adults with this syndrome observed during the past ten years at the University