tbuckley/cabot-search huggingface dataset:
American College of Physicians Guidelines on Cholesterol Screening
Authors: Philip Altus
Journal: Annals of Internal Medicine (1996)

Letters15 December 1996American College of Physicians Guidelines on Cholesterol ScreeningPhilip Altus, MDPhilip Altus, MDUniversity of South Florida College of Medicine, Tampa, FL 33606.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-125-12-199612150-00017 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The guidelines on cholesterol screening published by the American College of Physicians [1] are disturbing. They represent one step forward and two steps backward in achieving the goal of preventing cardiovascular disease. Furthermore, the College's approach is discordant with its mission: to establish the highest clinical standards, to be foremost in comprehensive education, to advocate responsible positions, and to serve the professional needs of its members.Cardiovascular disease is still the most common cause of both illness and death in the United States. Although there are many risk factors for this disease, lipid abnormalities are clearly both ...References1. American College of Physicians. Guidelines for using serum cholesterol, high-density lipoprotein cholesterol, and triglyceride levels as screening tests for preventing coronary heart disease in adults. Ann Intern Med. 1996; 124:515-7. Google Scholar2. Shepherd J, Cobbe SM, Ford I, Isles CG, Lorimer AR, MacFarlane PW, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group. N Engl J Med. 1995; 333:1301-7. Google Scholar3. Randomized trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Heart Study (4S). The Scandinavian Simvastatin Survival Study Group. Lancet. 1994; 344:1383-9. Google Scholar Author, Article, and Disclosure InformationAuthors: Philip Altus, MDAffiliations: University of South Florida College of Medicine, Tampa, FL 33606. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 December 1996Volume 125, Issue 12Page: 1007-1008KeywordsCardiovascular diseasesCholesterolDietExerciseLipidsLow density lipoproteinMedical risk factorsNatural history of diseaseScreening guidelinesStable coronary artery disease ePublished: 15 August 2000 Issue Published: 15 December 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Using the Medicine Clonidine To Treat Hot Flashes in Breast Cancer Patients Taking Tamoxifen
Journal: Annals of Internal Medicine (2000)

Summaries for Patients16 May 2000Using the Medicine Clonidine To Treat Hot Flashes in Breast Cancer Patients Taking TamoxifenSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-10-200005160-00038 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Tamoxifen, an antiestrogen medicine commonly used for treating breast cancer, often causes hot flashes as a side effect. Hot flashes can be uncomfortable and disrupt a woman's normal activities, including sleep. Estrogen replacement hormones are used to treat hot flashes in women without breast cancer but cannot be used in breast cancer patients because they might cause the cancer to grow. Some studies have shown that clonidine, a nonhormonal medicine sometimes used to treat high blood pressure, can reduce hot flashes in women who have gone through natural ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Oral Clonidine in Postmenopausal Patients with Breast Cancer Experiencing Tamoxifen-Induced Hot Flashes: A University of Rochester Cancer Center Community Clinical Oncology Program Study.” It is in the 16 May 2000 issue of Annals of Internal Medicine (volume 132, pages 788-793). The authors are K.J. Pandya, R.F. Raubertas, P.J. Flynn, H.E. Hynes, R.J. Rosenbluth, J.J. Kirshner, H.I. Pierce, V. Dragalin, and G.R. Morrow.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoOral Clonidine in Postmenopausal Patients with Breast Cancer Experiencing Tamoxifen-Induced Hot Flashes: A University of Rochester Cancer Center Community Clinical Oncology Program Study Kishan J. Pandya , Richard F. Raubertas , Patrick J. Flynn , Harry E. Hynes , Richard J. Rosenbluth , Jeffrey J. Kirshner , H. Irving Pierce , Vladimir Dragalin , and Gary R. Morrow Metrics Cited byPatients with Cancer and Survivors 16 May 2000Volume 132, Issue 10Page: 788KeywordsBreast cancerCancer treatmentEstrogen replacement therapyMenopauseMouthPrimary hypertensionQuality of lifeSleep ePublished: 15 August 2000 Issue Published: 16 May 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.Loading ...
Final Report of the Commission on Medical Education.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Table of Contents
Authors: Wei Huang, Luping Zhou, Hengli Guo, Youhua Xu, Yong Xu, Luís Cardoso, Nuno Vicente, Dírcea Rodrigues, Leonor Gomes, Francisco Carrilho, Mary Yannakoulia, Eva Ntanasi, Costas Anastasiou, Nikolaos Scarmeas, Júnia Maria, Geraldo Gomes, Jorge De Assis Costa, Rita De Cássia, Gonçalves Alfenas, Monique Francois, Matthew Graham, Evelyn Parr, Nancy Rehrer, Samuel Lucas, Stasinos Stavrianeas, James Cotter, Cintia Dias, Núria Amigó, Lisa Wood, Roger Mallol, Xavier Correig, Manohar Garg, Jin Lu, Ron Varghese, Lianzhen Zhou, Adrian Vella, Michael Jensen, Susann Blüher, Jakob Käpplinger, Sabine Herget, Sandra Reichardt, Yvonne Böttcher, Andrea Grimm, Jürgen Kratzsch, David Petroff, Susan Kralisch, Annett Hoffmann, Ulrike Lössner, Matthias Blüher, Michael Stumvoll, Mathias Fasshauer, Thomas Ebert, Joshua Joseph, Xu Wang, Ana Roux, Brisa Sanchez, Teresa Seeman, Belinda Needham, Sherita Golden, Jean-Philippe Drouin-Chartier, André Tremblay, Jean-Charles Hogue, Myriam Leclerc, Marie-Ève Labonté, Johanne Marin, Benoît Lamarche, Patrick Couture, Yoona Kim, Jennifer Keogh, Peter Clifton
Journal: Metabolism (2017)
Diarrhea of Travelers to Mexico. Summary of a Five-Year Study
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Internal Medicine
Authors: Steven A. Wartman
Journal: JAMA (1990)

Several important trends suggest that the 1990s will prove to be a critical decade for internal medicine. Recent data that involve the practice of general internal medicine indicate that general internists are experiencing some changes in practice patterns. More care is being provided in the ambulatory setting as internists are making fewer hospital visits and seeing more patients in the office.<sup>1</sup>Those patients who are admitted to the hospital tend to be very ill, older, or decompensating because of a previously diagnosed disease or are undergoing a specific procedure. Office patients, on the other hand, tend to need diagnostic efforts, chronic disease follow-up, and management of psychosocial dysfunction. In addition, increasing emphasis on preventive care and health maintenance requires internists to spend more time talking with and educating their patients. These changing practice patterns have pragmatic implications such as how internists may set up and staff their offices. They
Cardiovascular Pathology
Authors: Milton G. Bohrod
Journal: JAMA (1966)

In an era of good medical books this work is an outstanding example of what a large book on a specialized topic ought to be. The author evidently thinks that specialism is a platform from which to survey medicine, not a cubicle into which to retire. Consequently, the book has a wide scope and a broad base. The function of the pathologist is, apparently, understanding; therefore, much attention is given to physiological and chemical backgrounds. An occasional section is even predominantly clinical, as for instance the charming 7 1/2-page discussion of cardiac arrest and resuscitation. On the other hand, technical details and methodology receive abundant attention for those who want or need them. The background and the pathology of new diagnostic procedures and therapies, cardiac catheterization and use of pace-makers, for instance, receive proper attention. Each section is followed by a selective bibliography, which tends to be weighted on the
The scientific mind at work (and play)
Authors: H. S. Jacob
Journal: JAMA (1981)

<h3>The Thorndike Model</h3><h3>JAMA:</h3> Dr Jacob, what guidelines did you use to establish your clinical research program? <h3>Jacob:</h3> My own group has been presaged on the type of clinical investigation that culminated in the Thorndike Laboratory at the Boston City Hospital under William Castle, MD, with other greats, such as Maxwell Finland, MD, and Charles Davidson, MD. Within the hospital setting, physicians at the patient's bedside generated insights and trained their students to bring those insights back to the laboratory bench. This approach requires not only a strong subspecialty group, but also an environment in which there are many other subspecialists who have a similar interest in pathogenetic mechanisms of illness. One of the major problems in research training and clinical investigation is that they have become wildly superspecialized in that people believe that research in their own subspecialty can be done without knowledge of other subspecialties, and this leads
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
Authors: Marianne R. Spalinger, Stephanie Kasper, Claudia Gottier, Silvia Lang, Kirstin Atrott, Stephan R. Vavricka, Sylvie Scharl, Tina Raselli, Isabelle Frey-Wagner, Petrus M. Gutte, Markus G. Grütter, Hans-Dietmar Beer, Emmanuel Contassot, Andrew C. Chan, Xuezhi Dai, David J. Rawlings, Florian Mair, Burkhard Becher, Werner Falk, Michael Fried, Gerhard Rogler, Michael Scharl
Journal: Journal of Clinical Investigation (2016)

of the manuscript.SK, CG, TR, IFW, SL, KA, and WF performed experiments and were involved in data analysis.PMG and MGG were involved in vector design and subcloning.DJR and XD generated PTPN22-619W mice.HDB and EC performed experiments in keratinocytes and were involved in data analysis and interpretation.FM and BB performed experiments.ACC corrected and
Absorption and excretion of radioactively tagged dextroamphetamine sulfate from a sustained-release preparation
Authors: E. Rosen
Journal: JAMA (1965)

This study was undertaken to test the reliability of a sustained-release dosage form of dextroamphetamine sulfate. We tagged the drug with the radioactive carbon atom and gave four dosage regimens to 16 subjects following an incomplete block crossover design. The plasma and urine data obtained showed that the 15-mg sustained-release dosage form tested performed in a way comparable to 5 mg given three times each day, that it released its drug over a prolonged period, and that it was equivalent to other 15-mg regimens in the amount of drug made available for absorption. On the basis of these findings, we can say that the sustainedrelease dosage form tested is a reliable way to administer dextroamphetamine sulfate. The tests described herein, and tests of similar complexity, are becoming a more and more essential part of the evaluation of such dosage forms.
Lead poisoning in an art conservator
Authors: A. Fischbein
Journal: JAMA (1982)

A case of lead poisoning in a female art conservator is reported. The patient had experienced excessive lead exposure while restoring an antique Peruvian tapestry from the Chancay period (1000 to 1500 AD) using a powdered pigment (cinnabar), which had been recovered from the same tomb in which the tapestry was found. Over two months, prominent neurological, gastrointestinal, and diffuse muscular symptoms developed. Severe anemia accompanied by basophilic stippling of RBCs led to the diagnosis of lead poisoning, which was confirmed by markedly elevated blood lead levels (up to 130 μg/dL) and impairment of heme synthetic enzymes. The severity of the intoxication necessitated chelation therapy. Chemical analysis of the antique powdered pigment showed it to be the source of lead exposure, in that it contained about 1% lead. (<i>JAMA</i>1982;247:2007-2009)
Epidermoid cysts simulating rheumatoid nodules in the olecranon region
Authors: J. T. Wilson
Journal: JAMA (1970)

In four patients with rheumatic disease, a subcutaneous lesion in the olecranon region, which appeared to be a rheumatoid nodule clinically, proved to be an epidermoid cyst histologically. No pathogenetic relationships between the epidermoid cyst and the rheumatic disease were suggested. The biopsy findings must be interpreted with care, because, as illustrated in a fifth case, a degenerated rheumatoid nodule can be confused histologically with a ruptured epidermoid cyst.
Delivering Emotions
Authors: Elizabeth Corey
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
British Journal of Radiology, London
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Two Years' Clinical Experience with the Implantable Pacemaker for Complete Heart Block
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Postmortem tissue problems.
Journal: BMJ (1978)

in those drinking up to 50 g alcohol per day.The number of persons in the survey who consumed over 50 g per day was not enough to show whether this trend continued or whether it was reversed at high intake levels.The Kaiser-Permanente group also studied the relation of alcohol consumption and blood pressure and found that a raised blood pressure (both systolic and diastolic) was more common among those consuming 40 g alcohol per day than in non-drinkers.'9Two other studies, however, have failed to show any link between blood pressure and alcohol intake.20 21 Many questions about the toxic effects of alcohol remain unanswered.The average intake of alcohol necessary to cause damage is becoming established, but the nature of individual susceptibility is still imperfectly understood.
Physicians Discuss Facets Of Neck Pain
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal