tbuckley/cabot-search huggingface dataset:
The Croonian Lectures on the Relationship between Chemical Structure and Physiological Action
Authors: T. L. Brunton
Journal: BMJ (1889)

with much better results of operative interference than those whiech were obtained some years ago.Fourthly, treatment of whatever kind has been subjected to a somewhat unfair and deceptive test, for a large proportion of the cases have been too far W4vance4 *hen they have presented themselves to be brought to a satisfic ory result.Now, considering the presient condition of surgery-that, on the one hand, operative treatment has made great advances, and, on the other, that many observers are more than ever impressed with the reparative power evinced during early life-it i inevitable that, in combating such an affection as tuberculous joint disease, two main but widely diverging lines of treatment should be adopted and worked out, so that they may be weighed the one agamst-the other:-the one being founded on the principle of removing all the affected structures by excision of the joint, so that the remaining structures may undergo sound repair; the other consisting of placing the diseased joint under the most favourable conditions, in the hope that the tuberculous process may undergo-arrest, and that recovery may then ensue.-Towards a solution of the question which of these two methods yields the best result, some amount of evidence has already been produced, yet I am afraid a conclusive verdict is still in the dis- tance.For while some surgeons strongly advocate early excision, others do all they can to avoid the operation, and only resort to it when every other available means has been tried and has failed.It will be remembered that Mr. Barker, my predecessor here, last year, strongly advocated the treatment of tubercular disease of th-e joints by early and complete excision, and specified the grounds on which his views were based.All, I am sure, who heard the lectures were impressed with the c4re and thoroughness with which they had been prepared, and with the earnest and conscientious spirit in which the subject was teated.The case for excision, in fact, was presented in a manner which rendered full justice to it, and nothing was left unsaid that could be wi3ely urged in its favour.It thus becomes necessary, unless judgment is to go by default, that the case, if there is one, on the other side should be presented, and that it should be shown what objections there are to early excision, and what results can be obtaned by an alternative me- thod of treatment adopted at a similar stage of the disease.I will discuss these inquiries in the next lecture.
Error in Abstract
Authors: Philip Greenland, Yuichiro Yano, Donald Lloyd-Jones, Marcus Munafò
Journal: JAMA Cardiology (2017)

Yashashwi Pokharel, MD, MSCR; Yevgeniy Khariton, MD; Yuanyuan Tang, PhD; Michael E. Nassif, MD, MSc; Paul S. Chan, MD, MSc; Suzanne V. Arnold, MD, MHA; Philip G. Jones, MS; John A. Spertus, MD, MPH
Graduate medical education in the United States
Authors: A. E. Crowley
Journal: JAMA (1988)

<i>This section is an updated version of the material published in the</i>1988-1989 Directory of Graduate Medical Education Programs. <h3>INTRODUCTION</h3> This annual report on graduate medical education in the United States for the 1987-1988 academic year contains data on the number of programs accredited by the Accreditation Council for Graduate Medical Education (ACGME), by specialty and by region, and provides information on some characteristics of the persons in these programs. In 1986, the ACGME accredited, through the Residency Review Committee for Internal Medicine, programs in nine subspecialties of internal medicine and, through the Residency Review Committee for Pathology, programs in chemical pathology and medical microbiology. Recently, the special requirements for programs in child neurology, geriatrics, hand surgery, musculoskeletal oncology, orthopedic sports medicine, pediatric orthopedics, and radioisotopic pathology were approved. Review and accreditation of programs in these subspecialties have begun. <h3>RESIDENT AND RELATED TERMS</h3> In the medical education community the terms
Mumps Meningoencephalitis
Authors: Parvin H. Azimi
Journal: JAMA (1975)

MUMPS meningoencephalitis is usually a benign self-limiting disease; its clinical features are fever, headache, nausea, vomiting, and meningeal signs. The clinical course is of short duration, and death or major neurological complications are rare. The patient with mumps meningoencephalitis described in this report is unusual because of the persistence of an elevated cerebrospinal fluid (CSF) protein level and pleocytosis. <h3>Report of a Case</h3> An 11-year-old boy was admitted to Columbus (Ohio) Children's Hospital on Aug 6, 1973. Five days prior to admission, earache, fever, vomiting, and ataxia had developed. The following day, his temperature rose to 40 C (104 F). His physician gave him an injection of penicillin, and ampicillin in a dosage of 500 mg orally every six hours was prescribed. In spite of antibiotic therapy, his illness progressed and he was admitted to the hospital because of confusion and visual hallucinations. At the time of admission, his temperature
Advantages and Motivations Uncertain Behind Use of Brachytherapy for Breast Cancer Radiotherapy
Journal: JNCI Journal of the National Cancer Institute (2011)

Accelerated partial breast irradiation using brachytherapy (APBIb) for the treatment of breast cancer has been rapidly increasing over the last several years in the U.S. as an alternative to standard whole-breast irradiation (WBI), according to a study published December 16th in the Journal of the National Cancer Institute.Various types of APBI recurrence (external beam radiation, intraoperative radiotherapy, brachytherapy using multiple interstitial catheters, or intracavitary brachytherapy using a balloon catheter) deliver radiation to breast tissue at the highest risk of recurrence.Advantages of these techniques include decreased treatment time and less radiation to uninvolved portions of the breast and normal tissues.Disadvantages of APBI include the possibility that tumor cells in a different part of the breast will remain untreated, which could lead to increased local recurrence.Because of the potential limitations of APBI, in 2009 the American Society for Radiation Oncology (ASTRO) convened a task force of breast cancer experts to develop criteria for use of APBI off-protocol.They proposed three groups of APBI appropriateness: suitable, cautionary and unsuitable, based on patient characteristics and clinical factors.
Leads from the MMWR. Rabies postexposure prophylaxis with human diploid cell rabies vaccine: lower neutralizing antibody titers with Wyeth vaccine
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Irradiation and contaminated meat
Authors: M. F. Jacobson
Journal: JAMA (1995)

<h3>To the Editor.</h3> —Assistant Secretary Philip R. Lee lauded the ability of irradiation to reduce foodborne illness,<sup>1</sup>but he failed to acknowledge the potential risks to workers and the environment that would result from widespread use of irradiation by poultry processors and others. He also ignored irradiation-induced vitamin losses. Instead of installing irradiation facilities at meat and poultry slaughterhouses and packinghouses, the US Food and Drug Administration and Department of Agriculture should require good manufacturing practices (hazard analysis and critical control points) and establish microbiological standards to ensure the safety of our food supply. Not only would that be more acceptable to many consumers, it could also be less expensive. In the short run, US Department of Agriculture estimates that irradiation could add as much as 10 cents per pound to the cost of meat (oral communication, Tanya Roberts, Economic Research Service, July 16,1994). Estimates for on-site cobalt 60
Athlete drug testing receiving more attention than ever before in history of competition
Authors: V. S. Cowart
Journal: JAMA (1989)

ONE OUTCOME of the Olympic Summer Games in Seoul, South Korea, was that drug testing of athletes came under sharper scrutiny. Drug testing has continued to be news in the months since the Games. The International Olympic Committee is taking a second look at some of its approved laboratories. William J. Bennett, PhD, the federal drug coordinator, is meeting with commissioners and player representatives of several professional sports. And, although not related to athletic competition, the Pentagon is expected to begin a pilot program of testing some military personnel for anabolic steroids, making it the first federal government agency to do so (<i>JAMA</i>. 1989;261:2784-2785, 2788). <h3>Are Results Reliable?</h3> Questions about drug testing may be inevitable since the almost unvarying defense of every athlete with a positive drug test is that an error was made in the laboratory. The reliability of the drug-testing laboratories obviously is a major concern, not only for
Bicyclists Beware
Authors: Hugh H. Hussey
Journal: JAMA (1975)

In a forthcoming issue of<i>Archives of Neurology</i>, Eckman et al<sup>1</sup>describe three patients in whom ulnar neuropathy resulted from prolonged bicycle riding with consequent compression of the ulnar nerve at the wrist. The authors report one case in detail as follows: A 22-year-old student had ridden a bicycle across the United States, covering approximately 3,000 miles in 30 days. On or about the tenth day of the trip he noted the onset of weakness in both hands, not associated with any sensory disturbance. There was no associated pain in the neck or arms. The notable findings on examination were limited to the hands. There was bilateral weakness and atrophy of the dorsal interossei, the abductor digiti minimi, and the adductor pollicis muscles. The flexor carpi ulnaris muscles were normal bilaterally. Detailed sensory testing in the hands showed no deficits. The tendon reflexes in the upper extremities were equal
Aprotinin therapy as prophylaxis against postoperative pancreatitis in humans. A controlled evaluation
Authors: D. B. Skinner
Journal: JAMA (1968)

Pancreatitis of mild to severe degree developed in 16 of 99 patients after surgical procedures, such as exploration of the common bile duct, transduodenal sphincterotomy, and gastric resection for duodenal ulcer, were performed in the vicinity of the pancreas. The incidence of this complication was higher in younger patients. The use of the proteinase inhibitor, aprotinin, did not prevent pancreatitis from occurring postoperatively in comparison to a placebo in a prospective double-blind study.
Hemodialysis at satellites
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Anti-CD19 chimeric antigen receptor T cells preceded by low-dose chemotherapy to induce remissions of advanced lymphoma.
Authors: James Kochenderfer, Robert Somerville, Tangying Lu, Victoria Shi, James C. Yang, Richard Sherry, Christopher Klebanoff, Udai S. Kammula, Stephanie L. Goff, Adrian Bot, John Rossi, Marika Sherman, Arianne Perez, Allen Xue, Tatyana A. Feldman, Jonathan W. Friedberg, Mark J. Roschewski, Steven Feldman, Lori McIntyre, Steven A. Rosenberg
Journal: Journal of Clinical Oncology (2016)

LBA3010 The full, final text of this abstract will be available at abstracts.asco.org at 7:30 AM (EDT) on Sunday, June 5, 2016, and in the Annual Meeting Proceedings online supplement to the June 20, 2016, issue of the Journal of Clinical Oncology. Onsite at the Meeting, this abstract will be printed in the Monday edition of ASCO Daily News.
Research and Development
Authors: John Lister
Journal: New England Journal of Medicine (1972)

THE report by Lord Rothschild1 on the future of government-sponsored research and development (R & D) has stimulated a keen debate among the scientists of the country on the most appropriate method of promoting research. Lord Rothschild, head of the government's Central Policy Review staff, in his introduction states his belief that the organization and management of R & D should be logical, flexible, humane and decentralized, and emphasizes the point that his report is concerned with the establishment of the principles on which such an efficient system must rest and the consequences of accepting and implementing them. He then . . .
Editorial Opinions of the Medical Press.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Acute Cholecystitis
Authors: Robert E. Hermann
Journal: JAMA (1975)

FOR MANY years, the management of acute cholecystitis has been a controversial issue: should cholecystectomy be performed as an emergency procedure, should it be performed after a short period of diagnostic evaluation and medical treatment, or should the acute inflammatory process be treated medically and cholecystectomy delayed six to eight weeks until the inflammation has subsided? The principal arguments in favor of early operation are as follows: (1) In acute cholecystitis, the gallbladder is frequently obstructed and distended, and there is a 5% to 10% risk of ischemic necrosis of the wall of the gallbladder or of perforation. This is more likely to occur in the elderly, in patients with diabetes, and in those with atherosclerosis. (2) Early operation removes the inflamed organ promptly and avoids the need for a second hospitalization. (3) Recent studies have shown that if the operation is performed within 24 to 72 hours after the
Survival in cerebral palsy
Authors: P. Cohen
Journal: JAMA (1966)

Eighty-eight deaths occurred in a study group of 1,416 individuals with cerebral palsy under the age of 21 years during 8,031 person-years of follow-up. This represented an eight- to ninefold excess over "expected" mortality— the smallest excess being in the spastic individuals (tripling) and the largest in patients with multifocal disease and mixed deficits (18-fold increase). The relative longevity of noninstitutionalized individuals with cerebral palsy calls for long-range planning different from that which is adequate for the markedly accelerated mortality of their institutionalized counterparts.
Questions and Answers
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
'More!' Cry children as Congress shakes its head
Authors: A. A. Skolnick
Journal: JAMA (1995)

WHILE CONGRESS is preparing legislation that would seriously cut funding for federal food assistance programs, a newly completed study shows that some 4 million children younger than 12 years in the United States go hungry during at least part of the year. Almost 10 million additional children in low-income families are at risk of hunger and its farreaching health and psychosocial consequences. The findings of the 3-year, nationwide survey were released by the Food Research and Action Center, Washington, DC, a private, national not-for-profit organization dedicated to eliminating hunger and undernutrition in the United States. According to the center, its study, called the Community Childhood Hunger Identification Project, is the most rigorous and comprehensive investigation of childhood hunger in the United States carried out to date. "The study rigorously documents what people at the front lines have been saying for years— hunger is a problem among the nation's low-income families,"
THE METABOLISM IN OBESITY
Journal: JAMA (1925)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Validation of A Clinical Prediction Rule for Risk Stratification of Recurrent Venous Thromboembolism In Patients with Cancer-Associated Venous Thromboembolism
Authors: Martha L Louzada, Marc Carrier, Alejandro Lazo-Langner, Vi Dao, Jerry Zhang, Michael J. Kovacs, Agnes Y. Lee, Mark N. Levine, Guy Meyer, Marc Rodger, Philip Wells
Journal: Blood (2010)
Insomnia
Authors: Hugh H. Hussey
Journal: JAMA (1974)

Almost everyone may experience insomnia at one time or other. Long latitudinal trips by air, for example, nearly always disturb the traveler's sleeping pattern for a few days to a week or longer. More serious to the person involved is the problem of chronic insomnia, which, unfortunately, may have an iatrogenic origin. In this issue ofThe Journal(p 514) Kales et al report studies, in a sleep laboratory, on ten patients who had been taking hypnotic drugs for periods ranging from months to years. In spite of their continued use of the drugs, the patients' insomnia persisted. Their sleep patterns while taking their accustomed doses of hypnotics were compared to the sleep patterns of 15 other insomniacs who were not taking hypnotic drugs. The percentage of rapid eye movement (REM) sleep was significantly lower in most of the drug users than in the control insomniacs. Also, more of the
Occupational hazards for operating room-based physicians. Analysis of data from the United States and the United Kingdom
Authors: A. A. Spence
Journal: JAMA (1977)

Comparative analysis of data from three large retrospective surveys in the United States and the United Kingdom reaffirms an increased incidence of spontaneous abortion among female physicians working in the operating room. The live-born children of female physicians exposed in the operating room also had substantially more congenital abnormalities. Male anesthetists, compared with nonanesthetist physicians, had an increased incidence of hepatic disease; there was also an increased frequency of congenital abnormality in their children. The incidence of spontaneous abortion in wives of male anesthetists and in the rate of cancer among exposed male anesthetists was similar to control. Despite differences in survey methods and analysis, there was remarkable agreement in conclusions to be drawn from the independent studies. (<i>JAMA</i>238:955-959, 1977)