tbuckley/cabot-search huggingface dataset:
Unusual moles play leading role in new strategies for predicting and preventing malignant melanoma
Authors: M. F. Goldsmith
Journal: JAMA (1987)

THE CASE AGAINST dysplastic nevi, long considered suspects in the malignant melanoma mystery, appears to be growing stronger based on new evidence. These atypical pigmented moles have been identified as frequent precursors of the worst form of skin cancer in individuals and families where they flourish. At the annual meeting in New Orleans of the American Academy of Dermatology, several investigators presented recent findings about this relationship and suggested directions for future research. Darrell S. Rigel, MD, clinical instructor in dermatology, New York University (NYU) School of Medicine, New York City, and colleagues have developed a five-category method of ranking the risk of developing melanoma for persons who have many dysplastic nevi. The scale, said Rigel, is based on a scheme originally suggested by two physicians at the National Cancer Institute in Bethesda, Md: Kenneth H. Kraemer, MD, research scientist, and Mark Greene, MD, senior clinical epidemiologist (<i>Derm Clin</i>1985;3:225-238;
In brief
Journal: BMJ (2015)

In the news item "Cases of female genital mutilation in England rose by more than 1000 in three months" (BMJ 2015;351:h5180, doi:10.1136/bmj.h5180),we incorrectly said that in the three months to June this year 43 reinfibulation procedures were performed when, in fact, this should have read 43 deinfibulation procedures were recorded.We would also like to clarify that where we stated that a total of 1036 new cases of female genital mutilation were recorded in England between April and June 2015, this refers to women and girls with FGM who have had their FGM information collected in the FGM Enhanced Dataset for the first time.
International Symposium on Cellular and Molecular Biology of Hemopoietic Stem Cell Differentiation
Journal: JNCI Journal of the National Cancer Institute (1981)

Journal Article International Symposium on Cellular and Molecular Biology of Hemopoietic Stem Cell Differentiation Get access JNCI: Journal of the National Cancer Institute, Volume 66, Issue 3, March 1981, Page 609, https://doi.org/10.1093/jnci/66.3.609-d Published: 01 March 1981
As a medical student I never enjoyed hospital medicine, but was always assured by older students and doctors that things would improve after I graduated. So, perhaps foolishly, I continued on in the hope that everything would get better. Unfortunately, I am now in my F2 year and nothing has changed. General practice has never appealed to me. I am required next month to make important decisions about how to progress in medicine. I would like some advice on careers available to me outside …
Authors: Sabina Dosani
Journal: BMJ (2007)

Platinum remains the most active drug class in ovarian cancer treatment; however, new single-agent and combination therapies are needed to improve the clinical outcome of ovarian cancer therapies. Oxaliplatin, a third-generation platinum derivative, has shown effective antitumor activity and a favorable toxicity profile in epithelial ovarian cancer. Preclinical evidence of the synergistic cytotoxic effect of oxaliplatin in combination with several other chemotherapeutic agents and clinical evidence of the absence of any dose-limiting hematologic toxicity associated with this agent have made oxaliplatin an attractive compound for combination agent therapy. This article reviews the current status of the clinical application of oxaliplatin alone and in a combination regimen in epithelial ovarian cancer treatment.
Systemic Actinomyces Infection
Authors: Suzanne M. de la Monte
Journal: JAMA (1982)

THE INTRAUTERINE contraceptive device (IUD) is used by more than 3 million women in the United States.<sup>1</sup>Although it is more than 95% effective and does not interfere with the natural hormonal cycle, it is not without complications. Aside from excessive bleeding and pain during menstrual periods and increased risk of pelvic inflammatory disease, infections caused by<i>Actinomyces</i>organisms have been well demonstrated to occur in association with use of an IUD.<sup>2</sup>Uterine actinomycosis infection is usually superficial,<sup>3</sup>but it is potentially invasive<sup>4</sup>and may be fatal.<sup>5</sup>Establishment of the correct diagnosis followed by removal of the IUD and appropriate antibiotic therapy are recommended when<i>Actinomyces</i>is detected in a vaginal Papanicolaou smear. We describe herein a 28-year-old woman who had been using an IUD and who had systemic<i>Actinomyces</i>infection and a brain abscess develop several years after removal of her uterus and fallopian
Knowledge of the Purpose of Community Water Fluoridation—United States, 1990
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
HIATUS HERNIA
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PNEUMOPERITONEUM AS A LAPAROTOMY ADJUNCT
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Benign intracranial hypertension. Sequel to tetracycline therapy in a child
Authors: J. C. Maroon
Journal: JAMA (1971)

Benign intracranial hypertension developed in a 7-year-old boy following tetracycline administration and subsided after discontinuing therapy with the drug. Although this complication is well recognized in infants with open fontanelles, to our knowledge this is the first case reported in a child after cranial suture closure.
Letter Rules and Reminders
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"THE QUESTION OF POSITIVE WASSERMANN REACTIONS CAUSED BY THE INTRAVENOUS ADMINISTRATION OF ARSPHENAMIN"
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Survival From Early, Intermediate, and Late Stages of HIV Infection
Authors: Cheryl Enger
Journal: JAMA (1996)

<h3>Objective.</h3> —To estimate expected survival time among homosexual men infected with the human immunodeficiency virus type 1 (HIV-1) by (1) the calendar period before (1985-1988) and after (1989-1993) the widespread availability of acquired immunodeficiency syndrome (AIDS) treatments with antiretroviral and prophylactic interventions, and (2) stage of HIV disease. <h3>Design.</h3> —A prospective cohort study. A group of HIV-1—infected homosexual men were followed from July 1985 through June 1993 and evaluated every 6 months for the presence of clinical symptoms and measurement of the CD4 cell count. To measure the effectiveness of AIDS therapies in this nonrandomized study, we used 2 calendar periods as proxy measures of relative intensity of exposure to antiretroviral therapy. Stage of infection was defined by CD4 cell count and presence of HIV-related clinical symptoms or AIDS. <h3>Setting and Study Participants.</h3> —Homosexual men infected with HIV-1 from the Multicenter AIDS Cohort Study. <h3>Main Outcome Measure.</h3> —Survival time based on stage of HIV infection. <h3>Results.</h3> —The percentage of HIV-1—infected individuals free of AIDS and clinical symptoms at baseline who survived 2.5 years according to baseline CD4 cell counts of 0 to 0.100, 0.101 to 0.200, and 0.201 to 0.350× 10<sup>9</sup>/L was 22%, 53%, and 83%, respectively, for the 1985-1988 calendar period, compared with 54%, 71%, and 91%, respectively, for men in the 1989-1993 calendar period. Among men free of AIDS with CD4 cell counts of greater than 0.350× 10<sup>9</sup>/L, the relative hazard of mortality was 1.6 to 2.3 times higher for those with clinical symptoms compared with those free of clinical symptoms. <h3>Conclusions.</h3> —Survival of AIDS-free HIV-1—infected individuals with CD4 cell counts of less than 0.350× 10<sup>9</sup>/L has improved since antiretroviral and HIV prophylactic treatments have become available, but the long-term prognosis remains poor. (<i>JAMA</i>. 1996;275:1329-1334)
Neuronal Cell Cultures as Toxicologic Test Systems
Authors: Phillip G. Nelson
Journal: Environmental Health Perspectives (1978)

Neuronal cell cultures now represent well-characterized systems with which acute and chronic toxicologic effects of a variety of agents can be evaluated. Extensive synapse formation occurs over a period of days and weeks in these cell cultures and can be assayed semiquantitatively by morphological and electrophysiological means. Detailed morphophysiologic correlations can be made using a technique for injecting an intracellular marker protein, horseradish peroxidase. A variety of neurochemical indices of development, such as transmitter-related enzyme levels, can also be conveniently determined. The developing neuron and its synaptic connections are important objects of investigation since they may be particularly vulnerable to pathogenic materials. Examples of the effects of acute (opiate) and chronic (inhibitory aminoacid) treatments on synaptic function are given.
Hazards of dietary supplements
Authors: R. M. Gulley
Journal: JAMA (1979)

<h3>To the Editor.—</h3> Recently one of us had occasion to embark on a protein-supplemented fast. While on the way to a noon meeting that promised to be particularly dull, and while suffering moderate hunger, this person purchased a package of 12 mints advertised as being sugar-free. Paying no attention to the label, he proceeded to consume all of the 12 mints during the two-hour meeting. Thirty minutes after the last mint was consumed, he began to experience marked abdominal distention, passed extremely large amounts of flatus, and experienced abdominal cramping. This was followed shortly by the development of profuse, watery diarrhea that persisted for the next 30 minutes and amounted to an estimated 1 to 1.5 L of fluid. Five hours after consuming the mints, the subject ate his evening meal, which consisted of 180 g (6 oz) of steak, and noted persistent vague abdominal distress with considerable flatus. Thirty
Effectiveness of mass media campaigns to reduce alcohol consumption and harm: a systematic review
Authors: Ben Young, Sarah Lewis, Srinivasa Vittal Katikireddi, Linda Bauld, Martine Stead, Kathryn Angus, Mhairi Campbell, Shona Hilton, James Thomas, Kate Hinds, Adela Ashie, Tessa Langley
Journal: The Lancet (2017)
Respiration Physiology, Amsterdam
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Infectious mononucleosis
Authors: P. Lennon, M. Crotty, J. E. Fenton
Journal: BMJ (2015)

Infectious mononucleosis is commonly seen in both the community and the hospital setting.Patients usually present with a sore throat and often presume that an antibiotic is required.It is therefore important to dispel the many myths relating to the condition with appropriate patient education.Knowledge of the clinical course of the disease, as well as potential complications, is paramount.In an information age, difficult questions may arise for a general practitioner, emergency doctor, or trainee in ear, nose, and throat medicine.The aim of this review is to assist those who encounter infectious mononucleosis in the adolescent and adult population.
The SPPL3-defined glycosphingolipid repertoire orchestrates HLA class I-mediated immune responses
Authors: Marlieke L.M. Jongsma, Antonius A. de Waard, Matthijs Raaben, Tao Zhang, Birol Cabukusta, René Platzer, Vincent A. Blomen, Anastasia Xagara, Tamara Verkerk, Sophie Bliss, Xiangrui Kong, Carolin Gerke, Lennert Janssen, Elmer Stickel, Stephanie Holst, Rosina Plomp, Arend Mulder, Soldano Ferrone, Frans H.J. Claas, Mirjam H.M. Heemskerk, Marieke Griffioen, Anne Halenius, Hermen Overkleeft, Johannes B. Huppa, Manfred Wuhrer, Thijn R. Brummelkamp, Jacques Neefjes, Robbert M. Spaapen
Journal: Immunity (2021)
Fisiopatología humana.
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
OSTEITIS PUBIS
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Trends in Ischemic Heart Disease Deaths— United States, 1990-1994
Journal: JAMA (1997)

In 1994, a total of 481,458 persons died as a result of ischemic heart disease (IHD), which comprises two thirds of all heart diseases--the leading cause of death in the United States. This report presents trends in IHD mortality in the United States for 1990-1994 (the latest year for which data are available) and compares these trends by race, sex, and state. These findings indicate IHD death rates decreased from 1990 through 1994; however, the rate of decline was slower than rates of previously observed declines.
Improving the survival rate of acute-on-chronic liver failure patients complicated with invasive pulmonary aspergillosis
Authors: Danli Chen, Zhiping Qian, Haibin Su, Zhong-ji Meng, Jun Lv, Yan Huang, Yanhang Gao, Jingyuan Liu, Caiyan Zhao, Hongbo Gao, Yu Chen, Jie Xia, Liang PENG, Tao Han, Jinhua Hu, Yu Shi, Jinjun Chen
Journal: Journal of Hepatology (2020)
Laboratory diagnosis in the problem of suspected gonococcal infection
Authors: N. B. Riccardi
Journal: JAMA (1979)

Proper laboratory techniques are indispensable for the diagnosis and detection of gonorrhea. While the smear is efficacious in diagnosing symptomatic urethral gonorrhea in men, it is not reliable for cervical, rectal, pharyngeal, or asymptomatic urethral infection. We have seen the development of four systems of culturing geared toward the office practitioner or where a complete laboratory is not available. They are as follows: Transgrow (transport), Neigon JEMBEC (transport or nontransport), Isocult, and Microcult systems. The Neigon JEMBEC system offers a good choice for the office practitioner. The use of proper diagnostic and culturing techniques and routine screening should bring about an increase in the amount of gonorrhea detected, treated, and subsequently removed from the reservoir of infection. (<i>JAMA</i>242:2703-2705, 1979)