tbuckley/cabot-search huggingface dataset:
Urological Surgery
Authors: Richard G. Middleton
Journal: JAMA (1971)

This volume is a reissue of the well-known<i>Urological Surgery</i>by Austin Dodson, originally published in 1944. Austin Dodson, Jr., in this 4th edition, has retained too much of the earlier text, has brought some of it up to date, and has added new chapters by 12 other contributors. Large sections of this 1970 edition are identical to the 1944 edition, and while much of this is still sound urology, the reader quickly detects the somewhat different perspective of urology 26 years ago. Nephrectomy is often advocated where many urologists would now prefer kidney salvaging procedures. Nephropexy is prominent and overvalued by current standards. Pediatric urologic disorders are briefly mentioned, and many recent advances and present practices in pediatric urologic surgery are not acknowledged. On page 206, it is suggested that, if the surgeon finds it difficult to ligate the renal pedicle during nephrectomy, he may apply pedicle clamps and
Building or Extending a Hospital Department: Radiology a Path through the Planning Minefield (4)
Authors: E J Roebuck, D J Manton, G L Fordham
Journal: Journal of the Royal Society of Medicine (1987)

This is the fourth of a series of articles on the planning and building of anew radiology department or the extension of an old one. While the series focuses on a radiology department, it will be of interest to anyone who is planning any part of a hospital, particularly in the detailed information about the planning process and the part to be played by hospital staff during the subsequent building and commissioning. (The first article in the series appeared in the January issue, p 40.)
The medical school in the university
Authors: S. Muller
Journal: JAMA (1984)

EDUCATION in medicine has been part of the university mission since almost the very beginnings of the Western university nearly a millennium ago. One may wonder whether and why the role of the medical school is even topical. I believe that some not so subtle, and not so minor, changes have altered the role of medicine in the university, and that it is at least useful and at most necessary to appraise this transformation, even while it is still in process. It has become apparent that faculties of medicine have become involved in a migration from the center of the university toward some location on the perimeter. My initial assumption about this observation was that this was merely one natural, unavoidable component of the ongoing fragmentation of knowledge into an ever more complex constellation of specialties. We have, after all, long been aware that the impact of rapid advances in
Image of the Month—Diagnosis
Journal: JAMA Surgery (2013)

Esophageal InjuryT he CT scan was very concerning for esophageal injury.To further delineate the operative approach of right thoracotomy vs left neck exploration to examine the esophagus, a meglumine diatrizote (Gastrografin) swallow study was performed.The swallow study showed a bullet in the superior mediastinum in the cervicothoracic esophagus.This was best approached through the left neck (Figure 2).At exploration, a 4-cm tear in the cervical esophagus was noted.The cervical esophagus injury was closed in 2 layers, with closure of the mucosa with an interrupted inner layer of 4-0 nonabsorbable suture.The muscular layer of the esophagus was closed with interrupted Lembert sutures of 4-0 silk.A Jackson-Pratt drain was placed.Postoperatively, the patient did well; he did develop a thoracic duct leak that was conservatively managed.He had negative Gastrografin swallow study results on postoperative day 6, tolerated a general diet, and was subsequently discharged home on postoperative day 13.Transmediastinal gunshot wounds can be devastating injuries.In hemodynamically unstable patients, immediate operation is indicated as these patients may have major cardiac or vascular injury.In hemodynamically stable patients, however, the patient can be uninjured or have occult vascular, esophageal, or tracheobronchial injury.Evaluation of these patients traditionally includes angiography, bronchoscopy, esophagoscopy, and pericardial window.With the advent of contrast-enhanced CT scan, however, evaluation of injury can often be accomplished with only a CT scan showing the missile tract through the mediastinum.Certainly further investigational studies can be used to better delineate injuries that may require further intervention. 1enetrating esophageal injuries are an uncommon injury because of the esophagus's central and protected lo-
Tidsskrift for den Norske Laegeforening, Oslo
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Nose
Authors: Arne Høst
Journal: Allergy (1995)

•Rhinitis is a common symptom in food allergic patients, but rhinitis is rarely the only symptom. •Rhinitis due to adverse reactions to preservatives and colorants is very rare. •In anaphylactic systemic reactions to foods the rhinitis symptoms are caused by inflammatory mediators transported by the circulation. •In non‐anaphylactic reactions, the nasal inflammation and symptoms are probably induced by interaction with food allergens transported to the nasal mucosa via the blood circulation.
Analysis of intramedullary cell density by MRI using the multiple spin‐echo technique
Authors: Akira Masumoto, Shuji Yonekura, Munetaka Haida, Noriharu Yanagimachi, Tomomitsu Hotta
Journal: American Journal of Hematology (1997)

Analysis of the intramedullary cell distribution by magnetic resonance imaging (MRI) using conventional techniques involves subjectively interpreting images and estimating the cell distribution on the basis of signal intensity characteristics. In recent years, attempts have been made to achieve more precise analysis by new techniques, including chemical shift imaging. The multiple spin-echo (MSE) technique offers some advantages over conventional MRI. Since it allows measurement of the transverse magnetization decay curve at 32 or more points, it is capable of separating several tissue components with different relaxation times. In addition, this technique can be used with MRI instruments having a static magnetic field as low as 1.0 Tesla. In the present study, the intramedullary cell density was assessed by MRI using the MSE technique in 4 patients with aplastic anemia (AA), 4 patients with myelodysplastic syndrome (MDS), and 5 normal subjects. The water component of the marrow (with a short relaxation time) and the fat component (with a long relaxation time) were separated from each other by analyzing MR images obtained using the MSE technique, and the signal intensity ratio of the 2 components was calculated. The ratio was significantly higher in the AA group than in the other groups (AA vs. MDS, P = 0.0209, AA vs. normal controls, P = 0.0143). The present technique appears promising for quantitative assessment of the intramedullary cell density. Am. J. Hematol. 55:134–138, 1997. © 1997 Wiley-Liss, Inc.
Organotypic Culture of Fetal Lung Type II Alveolar Epithelial Cells: Applications to Pulmonary Toxicology
Authors: Susan G. Shami, Jane D. Aghajanian, Ronald L. Sanders
Journal: Environmental Health Perspectives (1984)

Techniques for isolation and culture of fetal Type II alveolar epithelial cells, as well as the morphologic and biochemical characteristics of these histotypic cultures, are described. Type II alveolar epithelial cells can be isolated from fetal rat lungs and grown in an organotypic culture system as described in this review. The fetal Type II cells resemble differentiated rat Type II cells in morphology, biochemistry, and karyotype as they grow in culture for up to 5 weeks. The cells of the mature organotypic cultures form alveolarlike structures while growing on a gelatin sponge matrix. The Type II cells also synthesize and secrete pulmonary surfactant similar in biochemical composition to that produced in vivo. This system has been used to study the effects of hormones on surfactant production and composition. The organotypic model has many potential applications to the study of pulmonary toxicology.
THE DIAGNOSIS AND PROGNOSIS OF LOSS OF VISION FROM ACCESSORY SINUS DISEASE
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effect of the revised AJCC staging (7th edition) on prognostic stratification in patients with surgically resected esophageal squamous cell carcinoma.
Authors: Gloria Terase Minella, James D. Luketich, Jon M. Davison, Dan Winger, Ryan M. Levy, Michael K. Gibson, Arjun Pennathur, Katie Sue Nason
Journal: Journal of Clinical Oncology (2013)

15 Background: Historically, the AJCC esophageal staging system separated patients into prognostic groups based on tumor, node, and metastasis (TNM) classifications. In 2010, the 7th edition (AJCC 7) significantly modified esophageal squamous cell cancer (ESCC) staging by separating ESCC from adenocarcinoma, incorporating tumor grade and location for node negative cancers, and stratifying by the number of involved regional nodes for node positive cancers. Our study aim was to determine whether AJCC 7 stage groupings provide improved survival prognostication compared to 6th edition (AJCC 6). Methods: We abstracted pathology and survival for 150 consecutive ESCC patients who underwent esophagectomy (1994-2012); 44 patients received induction therapy. AJCC 6 and AJCC 7 stages were assigned and overall survival analyzed from esophagectomy to death or most recent alive contact and censored at 60 months. Discriminatory ability and homogeneity within subgroups was assessed with Kaplan-Meier curves and monotonicity comparisons were evaluated with linear trend chi-squared tests. Overall survival was compared using Cox regression and Akaike Information Criterion (AIC) used to assess model fit. Results: Compared to AJCC 6, AJCC 7 upstaged 32 patients from IIa to IIb and 1 patient from IIb to IIIa and downstaged 3 patients from stage IIa to Ib. AJCC 7 subclassified 42 AJCC 6 stage III patients (17 IIIa, 10 IIIb and 15 IIIC). Median overall survival was 19 months. Kaplan-Meier log-rank statistic indicated stronger differentiation in AJCC 7 (19.8 vs 29.7). Cox regression likelihood (19.5 vs 26.1), AIC (618.1 vs 611.6), and linear trend chi-squared at 24- (17.5 vs 24.3) and 60-months (13.3 vs 17.3), were all superior for AJCC 7 stage groupings (AJCC 6 vs AJCC 7, respectively). Conclusions: AJCC 7 stage groupings demonstrate superior homogeneity, discriminatory ability and monotonicity compared to AJCC 6. Incorporating the extent of nodal disease, tumor location and tumor grade into the revised AJCC 7 stage classification improves prognostic stratification of surgically resected ESCC patients, including patients who received induction therapy.
Reply:
Authors: Tien-Hau Lien, Mei-Hwei Chang
Journal: Hepatology (2011)

We appreciate the comments from Dr. Wildhaber. Biliary atresia (BA) is the most common cause of liver death in children. Through the stool color card screening program, the prognosis of BA can be improved remarkably by early detection and timely surgery. The stool color card screening program is indeed a noninvasive, low-cost, and simple screening tool that is suitable for mass screening.1, 2 We are pleased to learn of the launch of the Swiss national biliary atresia screening program. This is a positive support to our stool card screening program in Taiwan. We hope to see more countries begin the implementation of the universal stool color card screening program for BA in children. As we understand, experts from quite a number of countries, including Canada, Malaysia, Australia, and the Philippines, among others, have started or are planning a pilot study for the stool color card screening program for BA. Our stool color card is available in other languages for new immigrants to Taiwan, including versions in English, Vietnamese, Thai, Indonesian, and Khmer (Kampuchea). In addition, the stool color card has been integrated into a child health booklet. Educational lectures were given to health and medical personnel, and periodically to day care workers.. Posters were also put up in local clinics and hospitals to propagate the related knowledge. Many previous studies had shown the importance of earlier detection for BA.3-5 Our experience provides evidence that the stool color card is a good screening tool for BA. Continuous efforts to actively promote early detection is mandatory to improve the long-term outcome of BA. We believe that the stool color card is a blessing for children's health. Tien-Hau Lien M.D.*, Mei-Hwei Chang M.D.*, * Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
Industrial support of biomedical publications
Authors: A. Soffer
Journal: JAMA (1983)

The mail each morning brings an announcement of a symposium, seminar, or postgraduate course presented by a pharmaceutical firm or medical device company. In everincreasing numbers, the proceedings of these regional or national educational programs appear in published form in clinical medical journals or as a special issue or supplement to these periodicals. In almost every instance, the total cost for the printing and mailing of the published version is supported by an industrial grant. Does the publication of such material constitute a constructive symbiotic relationship between industry and the scientific community, or do the proceedings really represent thinly disguised promotional efforts? If issues of integrity are at stake, can editorial boards provide reasonable guidelines, or should all offers of industrial funding for publications be rejected? These issues were discussed recently during an evening of candid dialogue among a group of clinical editors from the United States, Canada, Great Britain,
John Talbott, MD: editor and innovator
Authors: N. Y. Hoffman
Journal: JAMA (1983)

John H. Talbott, MD, has scaled the Andes, climbed the Colorado Rockies. Only last year, at 79, did he stop skiing ("Since I had never suffered a broken bone, I figured it was time to quit, not push my luck too far"). But he's still traveling, still lecturing. His bags are always packed and at the ready, whether for an expedition in 1929 with his beloved Harvard Fatigue Laboratory to study the physiological effects of high altitude without supplementary oxygen in Leadville, Colo; the International High Altitude Expedition to the Andes in 1935; repeat physiological experiments— in the California mountains 40 years later—on the original participants in the Colorado or Chilean expeditions; or now, to various places, to lecture and hold clinics on gout and arthritis. A perennial student as well, he graduated magna cum laude and Alpha Omega Alpha from Harvard Medical School, Boston, in 1929. A lover of
Microfluorimetric Analysis of a Purinergic Receptor (P2X 7 ) in GH 4 C 1 Rat Pituitary Cells: Effects of a Bioactive Substance Produced by Pfiesteria piscicida
Authors: Ana Clara Melo, Peter D. R. Moeller, Howard Glasgow, JoAnn M. Burkholder, John S. Ramsdell
Journal: Environmental Health Perspectives (2001)
THE DIAGNOSIS OF SYPHILIS BY SERUM REACTIONS.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AN IDIOSYNCRASY.
Authors: JAMES HARVEY RAYMOND
Journal: JAMA (1893)

"A peculiarity of constitution in which one person is affected by an agent, which in numerous others would produce no effect." It is not an uncommon occurrence in the practice of a physician to meet with a case wherein the judicious administration of a known harmless drug has produced alarming symptoms, and occasionally a case is seen in which unusual and unexpected effects are produced by different foods or even odors. This condition is known as "idiosyncrasy," and it is, at present, beyond the power of the physician to point out definitely a pathologic condition that may be considered a true etiologic factor. The best hypothesis yet offered is, that it is an exalted<i>reflex act.</i>I was told by Professor Walter S. Haines, of a clergyman in an eastern city, who, being the unhappy possessor of this peculiarity, was forced to request friends with whom he would dine, to
Fertility in Mice after Prenatal Exposure to Benzo[a]pyrene and Inorganic Lead
Authors: Petter Kristensen, Einar Eilertsen, Elin Einarsdottir, Aage Haugen, Vidar Skaug, Steinar Ovrebo
Journal: Environmental Health Perspectives (1995)

Experimental evidence suggests that inorganic lead and benzo[a]pyrene (BaP) suppress the development of primordial oocytes during fetal life. We examined the single and combined effects of prenatal exposure to BaP and moderate doses of lead. The fertility and ovarian morphology of F1 female NMRI mice in four treatment groups (nine mice per group) were investigated: control; lead (F0 given 1 g PbCl2/L in drinking water until mating); BaP (10 mg/kg body weight daily by oral intubation on days 7-16 of F0 pregnancy); and combined lead and BaP. F1 groups exposed prenatally to BaP either alone or in combination with inorganic lead showed markedly reduced fertility with few ovarian follicles compared to controls, whereas the group exposed to lead only had measures comparable to the controls. Mice exposed to both lead and BaP had a significantly longer gestation period (days to litter) compared to mice exposed only to BaP, lead, or controls. There is a nonsignificant indication that the compounds together further reduce number of offspring, number of litters, and litter size. These results suggest that lead and BaP have synergistic effects on impairment of fertility. The possibility of synergism may be of human relevance as inorganic lead and BaP are ubiquitous environmental pollutants.
Karl Braun's Last One Hundred Laparotomies.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Special Reports, Announcements, and Notices
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal