tbuckley/cabot-search huggingface dataset:
Nutritional Needs Surveys Among Elderly-Russia and Armenia, 1992
Journal: JAMA (1992)

The ongoing social, political, and economic changes in the 15 republics of the former Soviet Union have resulted in hyperinflation of the Soviet Union ruble (SUR), regional conflicts, and other hardships for the populations of these republics (1). In January 1992, a public health assessment in Russia indicated that the elderly--most of whom subsist on fixed incomes and among whom the prevalences of decreased mobility or chronic illnesses may be substantial--are at greatest risk because of declining social support. During March-May 1992, CARE, in collaboration with CDC, conducted three surveys in Russia and Armenia to assist in targeting the delivery of food and medical humanitarian aid to the most needy among the elderly. This report summarizes findings from these surveys.
First Official List of Motion Pictures on Food and Nutrition
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical Grievances.
Authors: None S. B.
Journal: JAMA (1896)

New York, July 18, 1896. <h3>To the Editor:</h3> —I respectfully submit the prevailing grievances of the profession, as near as I have been enabled to collect them: 1. Medical appointments in free hospitals, dispensaries, maternities and other medical charities, lodges, societies or clubs, free visiting physicians of boards of health and daily newspapers, vaccination by boards of health, drug store charities, free advice in newspapers, etc., shall be made under the supervision of our medical associations. These associations should appoint committees or engage persons to investigate the financial responsibility of all recipients of charity and collect accordingly. These sums to be applied to a general fund, which should be devoted to the assistance of needy practitioners. 2. The duration of medical appointments in institutions to be so regulated that all applicants shall have equal opportunities to serve. 3. Charitable medical institutions should not have the power to make rules prohibitive
THE NETHERLANDS
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prenatal Susceptibility to Carcinogenesis by Xenobiotic Substances Including Vinyl Chloride
Authors: Jerry M. Rice
Journal: Environmental Health Perspectives (1981)

The carcinogenicity of vinyl chloride for experimental animals when administered transplacentally is reviewed in comparison with known transplacental carcinogens, including those that, like vinyl chloride, are dependent on enzyme-mediated metabolic conversion to a reactive intermediate in maternal or fetal tissues. Vinyl chloride is converted by mixed-function oxidases to the reactive metabolite chlorooxirane, the carcinogenicity of which is also reviewed. Vinyl chloride is unequivocally a transplacental carcinogen for the rat. No evidence exists, however, to support the hypothesis that exposure of male rats to vinyl chloride or any other carcinogen confers an increased risk of tumor development on their progeny. Many structural analogs of vinyl chloride, i.e., substituted ethylenes, are also carcinogenic for adult animals, and can with confidence likewise be predicted to be effective transplacental carcinogens.
HIV
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
<i>The History of the Pennsylvania Hospital,</i>1751-1895. By Thomas G. Morton, M. D., assisted by Frank Woodbury, M. D. Publication authorized by the contributors at their annual meeting, May, 1893, and directed by the board of managers. Philadelphia:<i>Times</i>Printing House, 1895
Authors: J. M. M.
Journal: American Journal of Psychiatry (1897)
Features of autoimmune hepatitis in primary sclerosing cholangitis: An evaluation of 114 primary sclerosing cholangitis patients according to a scoring system for the diagnosis of autoimmune hepatitis
Authors: K Boberg
Journal: Hepatology (1996)

Overlapping features between primary sclerosing cholangitis (PSC and autoimmune hepatitis (AIH) have previously been noted. To assess systematically similarities between these disorders, we have evaluated 114 PSC patients (36 women; 78 men), all confirmed by endoscopic retrograde cholangiography (ERC), according to a scoring system proposed by The International Autoimmune Hepatitis Group for the diagnosis of AIH. The scoring system attributes positive or negative scores to the parameters sex, ratio of elevation of serum levels of alkaline phosphatase (ALP) vs. aminotransferase, serum levels of immunoglobulins and autoantibodies, viral markers, history of drug and alcohol intake, genetic factors, liver histology, and response to therapy. Two of the PSC patients (2%) obtained scores above 15 before treatment, satisfying the diagnostic criterion of "definite" AIH. Thirty-eight patients (33%) scored between 10 and 15 points and could be classified as "probable" AIH. The serum level of immunoglobulin G (IgG) was elevated in 68 patients (61% of 111 cases tested), and positive titers of antinuclear antibodies (ANA) or smooth muscle antibodies (SMA) were detected in 24 patients (22% of 111 cases tested). Thirty-five of the PSC patients (33% of 105 evaluable biopsy specimens) obtained positive scores for histological features similar to those of AIH, but the total score for histology was in the negative range in 72 patients (69%) because of the presence of biliary changes. The frequent finding of high scores in PSC patients underlines the similarities PSC may have with AIH. A modification of the scoring system, in particular by increasing the negative score for histological biliary changes, would improve its potential to discriminate between AIH and PSC.
Identification and etiology-dependent evaluation of diagnostic algorithms for early detection of hepatocellular carcinoma
Authors: Magdalena Swiatek-de Lange, Henry Chan, Teerha Piratvisuth, Tawesak Tanwandee, Satawat Thongsawat, Wattana Sukeepaisarnjaroen, Juan Ignacio Esteban Mur, Marta Bes, Bruno Köhler, Marcus-Rene Lisy, Christine Anna Belz, Vinzent Rolny, Ying He, Dave Morgenstern
Journal: Journal of Hepatology (2020)
Public Health Response to a Potentially Rabid Bear Cub—Iowa, 1999
Journal: JAMA (2000)

On August 27, 1999, a 5-6 month-old black bear cub in a petting zoo in Clermont, Iowa, died after developing acute central nervous system signs; the initial direct fluorescent-antibody (DFA) test results available on August 28 indicated the bear had rabies. On August 29, in response to the positive laboratory report, the Iowa Department of Public Health (IDPH) initiated a campaign to identify and inform persons potentially exposed to the bear's saliva. Within 72 hours, IDPH staff verified contact and exposure information for approximately 350 persons. Subsequent testing found no evidence of rabies virus in brain or spinal cord tissues. This report describes the public health response to this potential rabies outbreak and reviews testing procedures and protocols for rabies.
Lectures on Hernia and Its Radical Cure
Authors: J. Wood
Journal: BMJ (1885)

Umdilicalhernia.-Visccral (edz(-P',ieta Cal(CoIn s. -Op1iuons acted on by modern Sargeons.-Stractire and Develapinen t of the Hernial Areas.-D 'scent of Tetis.-ILperfections of Evolution as C ausses of Ihernia.-Anatomy cf thle pctrts of IJguinal Hernia.-Strueturceaed ,V cehaniena of thc C(anal and Rinys in Health and Disease.-Obliqsuead(I (direct Hern it.-Conf7ctliital1,Infantile.-Relation *to fjrorns of H1,1/(rocele.Mit. PRESIDENT AtN-J GENTLEMEN,-In undertaking(f the duty with which I have h1ad the honiour to be entrusted by the Coiiiucil of this College, my selectioln of the subject of my lectuires was naturally iniflueniced by the fact that, twenty-four years acgo, the authorities of this College, in conifem ring upon me the Jacksonian prize for an essay einbodying, the results of a new metliod of operating for the radical core in sixty cases of inguinal herniia, encouraged me greatly in the insvestigation of this fiel(d of research.Fully and deeply iinpr essed with the idea that it was only by patient and long sustained efforts tllat a subject of so much difficulty in ob- tainint, anid recording true results, for periods lonrr enouah to be worthy of reliance, could be satisfactorily elucidated, I have, during this long, initerval, continued to modify, to perfect, and to extend, the scope of the imethodl of operatilig which I then published for the iil'st timne.
Digest of data on the rheumatic diseases. 4. Morbidity and mortality, and hospital services for rheumatism sufferers.
Authors: R Benn
Journal: Annals of the Rheumatic Diseases (1972)

This report considers:(1) Data on sickness and injury incapacity for work in Great Britain in 1968-1969 from the Depart- ment of Health and Social Security (DHSS) Annual Report for the year 1970, supplemented by further details supplied by the Department.(2) Data on handicapped persons on the General Classes Registers of local authorities in England and Wales at December, 1969, supplied by DHSS.(3) Estimates from the Social Survey Division of the Office of Population Censuses and Surveys of the numbers of handicapped persons in Great Britain (Harris, 1971).(4) Data on Registered Disabled Persons at April 20, 1969, from the Employment and Productivity Gazette, September 1969.(5) Mortality data from the Registrar General's Statistical Review of England and Wales and the Annual Report of the Registrar General for Scotland for the year 1969.(6) Data on hospital staff, patients, and beds for 1970, supplied by DHSS and the Scottish Home and Health Department (SHHD), supplemented by data from Reports on Hospital In-Patient Enquiry (HIPE) for the years 1967 and 1968 (DHSS and Office of Population Censuses and Surveys).(i) Morbidity Sickness and injury incapacity in the year ended May 31, 1969, are shown in Table I.Insured people lost 37 0 million days from work through rheumatic complaints.This constituted 10-5 per cent. of all sickness and injury incapacity, and was over five times greater than the work loss due to industrial stoppages in 1969 (6 85 million days-Annual Abstract of Statistics, 1970).This represents an average loss of about 2 days (1 9 days) per year with rheumatism for every insured man or woman.off.However, apart from the fact that too much importance should not be attached to trends suggested by data from a single year, these latest data are the
American Academy of Ophthalmology 1979 Standing Committees
Authors: Robert Reinecke, William Albany, James Coles, Tenn Nashville, H Dunbar Hoskins, Francisco San, S Robert, William Kinder, Melvin Rubin, Ronald Burde, Ronald Louis, John Washington, Malcolm Lakeland, Robert Luxenburg, Jonathan Francisco, W Fla, George Albany, Waring Iii, Robert Whinery, David Paton, Paul Lichter, Thomas Arbor, Angeles Los, H William, M David, Joseph Worthen, Stanley Anderson, Robert Truhlsen, Angeles Christensen
Journal: Ophthalmology (1979)
THE TREATMENT OF FRACTURES OF THE NECK OF THE FEMUR BY IMMEDIATE REDUCTIO AND PERMANENT FIXATION.
Authors: N. SENN
Journal: JAMA (1889)

The treatment of a fracture of the neck of the femur is always a source of anxiety to the surgeon. In many instances the diagnosis is attended by unusual difficulties and not infrequently a fracture of this kind is overlooked, even after what appears to have been a thorough examination, while at other times, for want of a correct diagnosis, patients have been submitted to a long and debilitating treatment when no fracture existed. Patients suffering from this injury are with few exceptions advanced in years and liable to succumb to complications incident to prolonged confinement in bed. The marantic changes in the tissues of the aged and in persons rendered prematurely old by hereditary or acquired causes are known to be antagonistic to a rapid repair of such an injury, while at the same time the anatomical conditions at the seat of fracture are such as are well calculated
Helicobacter pylori
Authors: J Collins, B Bamford, J Bickley, B Johnston, J Sloan, B Boston, S Potts, R Owen
Journal: Gut (1992)

The source of infection and transmission mode of H. PG I and PG II were similar to values found in the Hpylori- infected subjects after successful treatment, and did not change in response to therapy.CONCLUSION: H.pylori infection is associated with reversible 24-h hyperpepsinogaemia.
Frozen increments
Authors: R H Baker, D R Naik, M D Beetham, A Padfield, M J Brown, M A Prenton, D R Cullen, F E Preston, G A B Davies-Jones, B Ross, T Duckworth, J D Shaw, D M Harris, L Spitz, M O Hindle, J D Ward, A E Jephcott, D J K White, P J Moorhead, A M Wilson, W Morris-Jones, E Worthy
Journal: BMJ (1976)
Interim analysis of ibrutinib plus paclitaxel for patients with metastatic urothelial carcinoma previously treated with platinum-based chemotherapy.
Authors: Daniel E. Castellano, Rafael Morales-Barrera, Ignacio Duran, Bhumsuk Keam, Ik Joo Chung, Tobias Arkenau, Ulka N. Vaishampayan, Mark Tuthill, Pablo Gajate, Sang Joon Shin, S. Paul Dang, Chia-Hsin Ju, Jennifer Lin, George Cole, Danelle Frances James, Oscar Reig Torras
Journal: Journal of Clinical Oncology (2019)

365 Background: In patients (pts) with advanced urothelial carcinoma (aUC) who progressed after platinum-based chemotherapy (CT), median overall survival (OS) is ~6 mo with CT and 8-10 mo with novel immune checkpoint inhibitors (ICIs). Ibrutinib (ibr), a first-in-class, once-daily, inhibitor of Bruton’s tyrosine kinase (BTK) with immunomodulatory properties, plus paclitaxel (pac) may be an effective treatment (tx) for pts with UC. Methods: One cohort in this phase 1b/2 study assessed ibr + pac in pts who had 1-2 prior tx (≥1 platinum-based and/or ICIs) with aUC. Recommended phase 2 dose per Phase 1b was ibr 840 mg/d + weekly pac 80 mg/m 2 in 21-d cycles; starting ibr dose: 560 mg/d. Preliminary BTK/other kinase assessment in baseline tumor biopsies was done by NanoString gene expression assay. Results: Based on interim analysis of the first 29 pts treated (ibr 840/560 mg/d, n = 25/4), median time on study/ tx was 7.2/2.3 mo (max tx: 11.5 mo). Median age was 67 y; 52% had 2 prior regimens (prior PDL-1 inhibitors, 100%). Unconfirmed ORR was 41% (complete/partial response: 10%/31%) and disease control rate was 62%. ORR was 71% for subset of 7 pts with only lymph node metastases, and 36% for 14 pts with 1 prior tx and 47% for 15 with 2 prior tx. Median duration of response was 4.2 mo (90% CI: 1.9, 7.1). Median PFS was 3.6 mo (90% CI: 1.6, 5.4) and median OS was 14.7 mo (90% CI: 7.7, 15.9). Follow-up for durability/survival is ongoing with 6 pts alive without progression, with 4 still on ibr tx. 76% of pts had grade ≥3 adverse events (AEs); 4 discontinued ibr + pac due to AEs and 1 had major hemorrhage. Pac exposure was not impacted by ibr; pac geometric mean C max (2066 ng/mL) and AUC 0-∞ (3813 ng.h/mL) were consistent with historical data. Preliminary tumor biopsy data showed a non-significant trend of higher BTK/ITK/BMX expression in responders; analyses are ongoing for ibr-targeted kinases. Conclusions: These results indicate that ibr + pac shows promising results for ORR and OS in pts with aUC previously treated with platinum-based CT and ICIs. There were no unexpected safety signals; ibr + pac seemed tolerable. Follow up of these and additional pts will support the efficacy and safety of ibr + pac in this study. Clinical trial information: NCT02599324.
Treatment of hepatic metastases in ocular melanoma. Embolization of the hepatic artery with polyvinyl sponge and cisplatin
Authors: C. H. Carrasco
Journal: JAMA (1986)

Patients with ocular melanoma have a high incidence of hepatic metastases, which primarily determine their length of survival. In an attempt to control the neoplastic disease in the liver, embolization of the hepatic artery with a combination of polyvinyl sponge (Ivalon) and a suspension of cisplatin was performed in two patients with hepatic metastases from ocular melanoma. Dramatic regression of the hepatic metastases, lasting 19 and six months, occurred in these two patients after one or two such treatments. Our preliminary, albeit successful, experience with this therapeutic approach suggests that it may offer relatively prolonged periods of remission and warrants further investigation. (<i>JAMA</i>1986;255:3152-3154)
Federal epidemiologists link ills to environs
Authors: D. E. Riesenberg
Journal: JAMA (1986)

Scientists at the Centers for Disease Control (CDC), Atlanta, understand the complexities of environment-health interactions. The CDC's Center for Environmental Health has investigated outbreaks of illness in which the causes ranged from rug shampoo to volcanic eruptions. In 1980, for example, symptoms of respiratory irritation among inhabitants of a city office building and a day-care center were traced to underdilution of commercial carpet cleaners. The dry residue, sodium dodecyl sulfate, turned out to be a potent respiratory irritant (<i>Environ Int</i>1982;8:337-341). Henry Falk, MD, of the Center for Environmental Health, says the group has conducted a dozen such indoor air quality investigations. Indoor studies have more recently been taken over by the CDC's National Institute for Occupational Safety and Health. Its records indicate that the tally of indoor air quality complaints investigated now exceeds 200. Also in 1980, the Center for Environmental Health had the opportunity to study an outdoor
New Approaches to Immunotoxicity Testing
Authors: Douglas L. Archer
Journal: Environmental Health Perspectives (1982)

New approaches to immunotoxicity testing are reviewed and discussed. A method of activating T-cells in vivo is presented which circumvents artifacts dur to viability effects encountered with in vitro mitogen assays. The use of adoptive transfer approaches to combine the advantages of in vitro manipulation with in vivo function assays is discussed relative to natural killer cells. The need for an in vitro metabolic activation step coupled to other in vitro immunologic assays is discussed.
Immunization and the prevention of influenza and pneumococcal disease in people with diabetes: American Diabetes Association.
Journal: Diabetes Care (2000)

I M M U N I Z AT I O N -The rationale for the use of influenza and pneumococcal vaccine in patients with diabetes is reviewed in the American Diabetes Association technical review "Use of Influenza and Pneumococcal Vaccine in People with Diabetes" (1) and can be summarized as f o l l o w s :• Patients with diabetes may have abnor- malities in immune function and presumed increased morbidity and mort a lity from infection.• Epidemiological studies support the fact that patients with diabetes (in part i c u l a r those with end organ complications of c a rdiac and renal disease) are at high risk for complications, hospitalization, and death from influenza and pneumococcal disease.• T h e re is sufficient evidence that people with diabetes generally have appro p r iate humoral immune responses to vacc i n a t i o n .• T h e re are few clinical trials of vaccine eff i- cacy specifically in patients with diabetes.• S u b g roup analysis of patients with dia- betes re p o rted in clinical narrative and c a s e -c o n t rol studies support the fact that vaccination against influenza has been e ffective in reducing hospital admissions during influenza epidemics.
Neuropsyche und Hirnrinde. Band II: Physiologische Grundlagen der Tiefenpsychologie unter besonderer Berücksichtigung der Psychoanalyse. Ein Handbuch für Studierende, Ärzte, Psychologen und Pädagogen.
Journal: JAMA (1931)

In a consideration of the relation of psychoanalysis to neuropsychiatry, the author has attempted to build on the conception of conditioned reflexes the conception of psychiatry which has for its basis certain anatomic and physiologic facts. This is a rare achievement even to have been attempted, since the psychoanalyst usually disregards the fundamental structures and functions of the nervous system in the development of his conception. This author, however, actually bases the workings of the mind on mechanisms of the brain and on this basis has written an extraordinarily interesting monograph.