tbuckley/cabot-search huggingface dataset:
Barrett's Esophagus
Authors: EUGENE M. BOZYMSKI
Journal: Annals of Internal Medicine (1982)

Barrett's esophagus denotes the presence of columnar epithelium in the esophagus instead of the usual stratified squamous epithelium. Barrett's esophagus had been thought to represent a mediastinal extension of the stomach in patients with a congenital short esophagus. Subsequent clinical and experimental data have established the abnormality as an acquired condition resulting from chronic gastroesophageal reflux. Although roentgenographic studies may show a mid-esophageal stricture or an esophageal ulcer, definitive diagnosis requires endoscopy with directed biopsy of erythematous mucosa in the esophagus, or manometrically guided biopsies for showing the presence of columnar epithelium above the lower esophageal sphincter. Although the origin of the cells causing this epithelium is still unclear, three distinct epithelial types have been found: atrophic gastricfundic, junctional, and specialized columnar. Esophageal strictures and esophageal ulcers are complications associated with Barrett's esophagus, but its major significance is the association with the development of adenocarcinoma of the esophagus. Treatment of Barrett's esophagus is aimed at preventing gastroesophageal reflux with the additional need for close endoscopic surveillance for the development of dysplasia or early adenocarcinoma. Whether the diagnosis of Barrett's esophagus mandates anti-reflux surgery (fundoplication) remains controversial.
STATUS LYMPHATICUS
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Zidovudine for the Prevention of HIV Transmission From Mother to Infant
Journal: JAMA (1994)

Worldwide, perinatal (i.e., mother to infant) transmission accounts for most human immunodeficiency virus (HIV) infections among children; in the United States, of the approximately 7000 infants born to HIV-infected mothers each year, 1000-2000 are HIV-infected. Strategies for reducing perinatally acquired HIV infection have included preventing HIV infection among women and, for HIV-infected women, avoiding pregnancy or refraining from breastfeeding their infants. On February 21, 1994, the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) and National Institute of Child Health and Human Development (NICHD) announced preliminary results from a randomized, multicenter, double-blinded clinical trial of zidovudine (ZDV) to prevent HIV transmission from mothers to their infants (AIDS Clinical Trials Group [ACTG] protocol 076). This report summarizes the interim results of that trial, which indicate effectiveness of ZDV for prevention of perinatal transmission.
TCT-677 Stentless vs. Stented Aortic Valve-in-Valve Implantation: Insights from the Valve-in-Valve International Data Registry (VIVID)
Authors: Matheus S. Santos, Alison Duncan, John Webb, Vinayak Bapat, Thierry Lefevre, Guilherme F. Attizzani, Jose María Hernandez-García, Pedro A. Lemos, Robert C. Welsh, Alessandro Iadanza, Stefano Salizzoni, Marco Agrifoglio, Patrizia Presbitero, Giuseppe Bruschi, Dominique Himbert, Raj Makkar, Arash Salemi, Rui C. Teles, Antonio Marzocchi, Farrel Hellig, Sameer Gafoor, Tarun Chakravarty, Ariel Finkelstein, Ran Kornowski, Danny Dvir
Journal: Journal of the American College of Cardiology (2015)
Fulvestrant (FUL) 500 milligrams as endocrine therapy (ET) for hormone sensitive advanced breast cancer patients. The Ful500 prospective observational trial
Authors: L. Moscetti, M.A. Fabbri, P. Vici, C. Natoli, T. Gamucci, I. Sperduti, L. Pizzuti, L. Iezzi, E. Iattoni, C.L. Roma, A. Vaccaro, G. D'Auria, M. Mauri, E. Ruggeri
Journal: Annals of Oncology (2016)
Incorrect Medication
Journal: JAMA (2014)

Joseph P. McEvoy, MD; Matthew Byerly, MD; Robert M. Hamer, PhD; Rosalie Dominik, DrPH; Marvin S. Swartz, MD; Robert A. Rosenheck; Neepa Ray, MS; J. Steven Lamberti, MD; Peter F. Buckley, MD; Tania M. Wilkins, MS; T. Scott Stroup, MD, MPH
Major depressive disorder in patients with Wilson’s disease: relationship with liver disease, neurological disease and quality of life
Authors: Michelle Camarata, Aftab Ala, Uyen Kim To, Paula Zimbrean, Susan Rubman, Amar Patel, Anant Wadhwa, Kaitlin Maciejewski, Xuemei Song, Yanhong Deng, Ricarda Tomlin, Tugce Apdik, Ayse Coskun, Michael Schilsky
Journal: Journal of Hepatology (2020)
The hospice movement
Authors: S. G. Barber
Journal: JAMA (1979)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Public Opinion and Medical Education
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dr. J. McKeen Cattell Founder of Psychology Laboratory
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Predictive value of precore hepatitis B virus mutations in spontaneous and interferon-induced hepatitis B e antigen clearance*1, *2
Authors: A LOK
Journal: Hepatology (1995)

We previously reported two mutually exclusive mutations in the precore region of hepatitis B virus: Ml (T-1856, proline-serine substitution at codon 15) and M2 (A1896, stop codon at codon 28). This study was conducted to determine if the presence of precore mutants affect spontaneous or interferon (IFN)-induced hepatitis B e antigen (HBeAg) clearance. Sera from 201 hepatitis B e antigen positive Chinese patients (including 106 who participated in a controlled trial of IFN therapy) with chronic hepatitis B virus (HBV) infection were analyzed by direct sequencing of HBV DNA after amplification by polymerase chain reaction (PCR) assay. Forty-three (21%) patients had Ml (T-1856), and 20 patients (10%) had M2 (A-1896). During a follow-up period of 1 to 7 years, 75%, 28%, and 26% of those with M2 (A-1896), Ml (T-1856), and wild type sequence respectively, cleared HBeAg (P < .0001). Eighteen (67%) of 27 patients with wild-type sequence but none of 10 patients who had Ml (T-1856) in their initial samples developed M2 (A-1896) after loss of HBeAg (P < .0001). Sustained antiviral response was achieved in 55%, 0%, and 17% of interferontreated patients who had M2 (A-1896), Ml (T-1856), and wild-type sequence, respectively, initially (P = .04). However, patients with M2 (A-1896) were also more likely to have elevated pretreatment aminotransferase levels (P = .02). In summary, HBeAg-positive Chinese patients with M2 (A-1896) were more likely to clear HBeAg, and to do so earlier. Nevertheless, development or selection of M2 (A-1896) was not a prerequisite for HBeAg clearance. Interferon therapy did not increase the rate of HBeAg clearance in patients with M2 (A-1896) when stratified for aminotransferase levels.
HEMORRHOIDS
Authors: J. RAWSON PENNINGTON
Journal: JAMA (1926)

At the Ohio Valley Medical Association, just ten years ago, I<sup>1</sup>proposed a new classification of hemorrhoids into infective and noninfective groups, based, of course, on the relative virulence of the infection in the pile tumor. Since all examples are actually or potentially infective, I shall limit my remarks to this type, premising that it is essential that the focus be extirpated. The section reproduced in figure 1 is from the stump of a hemorrhoidectomy done by one of the "closed" methods; bacteria and a round-cell infiltration can be seen in the field. This patient was supposed to have "ulcer of the stomach," and was to have a gastroenterostomy performed; but the gastric symptoms promptly subsided after removal of the pathologic condition and provision of free drainage. A crater-like opening can be seen in the apex of the field, evidently nature's mode of permitting the excess products of infection
<i>QuickStats</i>: Number of Deaths Resulting from Unintentional Carbon Monoxide Poisoning,* by Month and Year — National Vital Statistics System, United States, 2010–2015
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

During 2010-2015, a total of 2,244 deaths resulted from unintentional carbon monoxide poisoning, with the highest numbers of deaths each year occurring in winter months. In 2015, a total of 393 deaths resulting from unintentional carbon monoxide poisoning occurred, with 36% of the deaths occurring in December, January, or February.
STATE CARE OF THE INSANE IN NEW YORK.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The epidemiologic necropsy for abdominal aortic aneurysm
Authors: M J McFarlane
Journal: JAMA (1991)

The epidemiologic necropsy measures the occurrence of unsuspected disease through the examination of necropsy records. The estimates of unsuspected disease should approximate what occurs in the living population. The necropsy records of the University of Kansas Medical Center (Kansas City) from 1950 to 1984 were examined for the occurrence rate of abdominal aortic aneurysms. Each adult patient was categorized as (1) without abdominal aortic aneurysm, (2) abdominal aortic aneurysm discovered as a necropsy surprise, or (3) abdominal aortic aneurysm diagnosed or suspected during life. Necropsy detection rates of unsuspected abdominal aortic aneurysms were compared with those found in five published screening surveys. The necropsy detection rate in men was 81 (0.019) of 4155 and was 28 (0.009) of 3142 in women, a difference that was statistically significant. When the necropsy series was adjusted to reflect the same demographic composition as the screening surveys, the results from necropsy and screening were statistically similar. In particular, two surveys from the United Kingdom showed screening detection rates among white men of 0.072 compared with a necropsy detection rate of 0.058. These results further support the use of the epidemiologic necropsy as a research tool for estimating the reservoir of disease in the population.
Defense Retirees Receive Better Coverage
Authors: B. Vastag
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Resident Burnout
Authors: Joshua A. Beckman, James C.-T. Fang
Journal: Annals of Internal Medicine (2002)

Letters15 October 2002Resident BurnoutJoshua A. Beckman, MD and James C.-T. Fang, MDJoshua A. Beckman, MDBrigham and Women's Hospital, Boston, MA 02115Search for more papers by this author and James C.-T. Fang, MDBrigham and Women's Hospital, Boston, MA 02115Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-8-200210150-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The report by Shanafelt and colleagues (1) and the accompanying editorial by Clever (2) demonstrate that resident burnout occurs with great frequency and may affect patient care. As Shanafelt and colleagues point out in their Table 4, these problems continue at levels unchanged over the past 15 years despite improvements in residency training, such as night float and smaller case loads. Trainees enter residency without practical knowledge yet are rapidly immersed in the care of sick patients. Worse, interns and residents change service, colleagues, and superiors every month. Medical residency is difficult and stressful.However, although the ...Reference1. Shanafelt TD, Bradley KA, Wipf JE, Back AL. Burnout and self-reported patient care in an internal medicine residency program. Ann Intern Med. 2002;136:358-67. [PMID: 11874308] LinkGoogle Scholar2. Clever LH. Who is sicker: patients—or residents? Residents' distress and the care of patients [Editorial]. Ann Intern Med. 2002;136:391-3. [PMID: 11874312] LinkGoogle Scholar3. Gillard JH, Dent TH, Smyth-Pigott PJ, Eaton J. Recent changes in the workload and clinical experience of pre-registration house officers: experiences over four years in south-west England. Med Educ. 2000;34:371-3. [PMID: 10760122] CrossrefMedlineGoogle Scholar4. Tanz RR, Charrow J. Black clouds. Work load, sleep, and resident reputation. Am J Dis Child. 1993;147:579-84. [PMID: 8488808] CrossrefMedlineGoogle Scholar5. Griffith CH, Wilson JF, Rich EC. Intern call structure and patient satisfaction. J Gen Intern Med. 1997;12:308-10. [PMID: 9159700] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Joshua A. Beckman, MD; James C.-T. Fang, MDAffiliations: Brigham and Women's Hospital, Boston, MA 02115 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoBurnout and Self-Reported Patient Care in an Internal Medicine Residency Program Tait D. Shanafelt , Katharine A. Bradley , Joyce E. Wipf , and Anthony L. Back Metrics 15 October 2002Volume 137, Issue 8Page: 699KeywordsDecision makingHospitalizationsPatientsResidency ePublished: 15 October 2002 Issue Published: 15 October 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Prevalence of Leisure-Time and Occupational Physical Activity Among Employed Adults--United States, 1990
Journal: JAMA (2000)

Regular physical activity and high levels of physical fitness offer numerous health benefits, such as reduced risk for cardiovascular disease, diabetes, obesity, some cancers, and musculoskeletal conditions (1). National rates for participation in leisure-time physical activity are consistently low for women, older adults, persons with low educational attainment, and racial/ethnic minorities (2). Public health recommendations for promoting physical activity emphasize moderate-intensity activities, building on recommendations for vigorous exercise to improve fitness (3,4). To determine the prevalence of leisure-time and occupational physical activity, data were analyzed for employed adults aged > or = 18 years in the 1990 National Health Interview Survey (NHIS). This report summarizes the results of the survey, which indicate that approximately half of adults who reported no physical activity during leisure time also reported that they performed at least 1 hour per day of hard physical activity at work.
Lectures on the Operative Treatment of Enlargement of the Prostate: Delivered before the Royal College of Surgeons of England
Authors: C. W. M. Moullin
Journal: BMJ (1892)

THE operations that have been performed for the relief of prostatic retention may be divided into palliative and radical.The former consist, for the most part, of cystotomy or drainage, perineal or suprapubic.The most elaborate is that practised by McGuire and Morris, of New York, in which the -new channel is made to run obliquely from the bladder to the -upper end of the suprapubic incision, and is lined with strips of skin transplanted from the sides.In some instances the
EDUCATIONAL ADVANCES
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal