Update in Nephrology
Authors: Stanley Goldfarb
Journal: Annals of Internal Medicine (1998)

Updates1 January 1998Update in NephrologyStanley Goldfarb, MD and William L. Henrich, MDStanley Goldfarb, MDFrom the University of Pennsylvania Health System, Philadelphia, Pennsylvania; and Medical College of Ohio, Toledo, Ohio.Search for more papers by this author and William L. Henrich, MDFrom the University of Pennsylvania Health System, Philadelphia, Pennsylvania; and Medical College of Ohio, Toledo, Ohio.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-128-1-199801010-00008 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Renal disease remains a prevalent and costly problem in the United States. The treatment of end-stage renal disease costs at least $11 billion a year. Both diabetes and drugs are common causes of renal failure, and much research has recently been done in these areas. Great attention has also been focused on the prevention of renal disease, an important endeavor for every physician.Diabetic Renal DiseaseIn 1996, two studies showed that calcium-channel blockers may have an important role in preventing renal failure in diabetic patients. Another study found that progression of renal disease in type 1 diabetes mellitus parallels ...References1. Viberti GC, Hill RD, Jarrett RJ, Argyropoulos A, Mahmud U, Keen H. Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus. Lancet. 1982; 1:1430-2. Google Scholar2. Kasiske BL, Kalil RS, Ma JZ, Liao M, Keane WF. Effect of antihypertensive therapy on the kidney in patients with diabetes: a meta-regression analysis. Ann Intern Med. 1993; 118:129-38. Google Scholar3. Klein R, Klein BE, Moss S, DeMets DL. Proteinuria in diabetes. Arch Intern Med. 1988; 148:181-6. Google Scholar4. Mogensen CE, Keane WF, Bennett PH, Jerums G, Parving HH, Passa P, et al. Prevention of diabetic renal disease with special reference to microalbuminuria. Lancet. 1995; 346:1080-4. Google Scholar5. Osterby R, Brekke IB, Gundersen HJ, Jorgensen HE, Lokkegaard H, Mogensen CE, et al. Quantitative studies of glomerular ultrastructure in human and experimental diabetes. Appl Pathol. 1984; 2:205-11. Google Scholar6. Klahr S, Levey AS, Beck GJ, Caggiula AW, Hunsicker L, Kusek JW, et al. The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of Diet in Renal Disease Study Group. N Engl J Med. 1994; 330:877-84. Google Scholar7. Hatala R, Dinh T, Cook DJ. Once-daily aminoglycoside dosing in immunocompetent adults: a meta-analysis. Ann Intern Med. 1996; 124:717-25. Google Scholar8. Chazan JA, London MR, Pono LM. Long-term survival of vascular accesses in a large chronic hemodialysis population. Nephron. 1995; 69:228-33. Google Scholar9. U.S. Renal Data System. USRDS 1995 Annual Data Report. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases; 1995. Google Scholar Author, Article, and Disclosure InformationAffiliations: From the University of Pennsylvania Health System, Philadelphia, Pennsylvania; and Medical College of Ohio, Toledo, Ohio.Corresponding Author: Stanley Goldfarb, MD, Department of Medicine, University of Pennsylvania Health System, 100 Centrex, 3400 Spruce Street, Philadelphia, PA 19104-4283.Current Author Addresses: Dr. Goldfarb: Department of Medicine, University of Pennsylvania Health System, 100 Centrex, 3400 Spruce Street, Philadelphia, PA 19104-4283. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEffects of multidisciplinary case management in patients with chronic renal insufficiency∗∗Access the “Journal Club” discussion of this paper at http://www.elsevier.com/locate/ajmselect/ 1 January 1998Volume 128, Issue 1Page: 49-55KeywordsACE inhibitorsBlood pressureCreatinineDrugsGlomerular filtration rateNSAIDsPregnancyRenal diseasesRenal failureType 2 diabetes Issue Published: 1 January 1998 Copyright & PermissionsCopyright © 1998 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...