tbuckley/cabot-search huggingface dataset:
Succinylcholine-induced hyperkalemia in neuromuscular disease
Authors: L. H. Cooperman
Journal: JAMA (1970)

The dangerously high levels of plasma potassium known to follow succinylcholine chloride administration in patients with burns or trauma have also been noted in patients with paraplegia or hemiplegia, muscular dystrophy, and multiple sclerosis. Of 40 patients with these neuromuscular diseases, 15 had increases in potassium levels between 1 and 6 mEq/liter after receiving succinylcholine chloride, 1 mg/kg of body weight. Most increases over 1 mEq/liter occurred in those patients who had been ill for less than six months or, if longer, who had disease of a progressive nature. The degree and extent of muscle paralysis seemed directly correlated with relaxant-induced hyperkalemia.
Effects of PBBs on Cattle. I. Clinical Evaluations and Clinical Chemistry
Authors: H. I. Durst, L. B. Willett, F. L. Schanbacher, P. D. Moorhead
Journal: Environmental Health Perspectives (1978)

Toxicosis was induced in pregnant heifers by feeding 25,000 mg/head/day of FireMaster BP-6, a commercial blend of polybrominated biphenyls (PBB). The PBB feeding decreased dry matter intake approximately 50% by 4 days exposure. Emaciated animals became anorexic a few days prior to death at 33 to 66 days. Weight losses of heifers average 80 kg. Other clinical signs observed were dehydration, diarrhea, excessive salivation and lacrimation, fetal death, abortion, and general depression as evidenced by depressed heart and respiratory rates. Clinical signs were apparent after 10 days exposure and progressively intensified along with loss of condition until death. Clinicopathologic changes included significantly increased serum glutamic-oxaloacetic transaminase and decreased serum calcium by 30 days exposure. Lactate dehydrogenase, urea nitrogen, and bilirubin were elevated, and serum albumin decreased by 36 to 40 days. Principal urine changes were decreased specific gravity and moderate proteinuria. Pregnant heifers fed 0.25 or 250 mg/head/day for 60 days and nonpregnant heifers fed 250 mg/head/day for 180 days displayed neither clinical signs nor clinicopathologic changes indicating adverse effects from PBB exposure. Post-exposure, all heifers exposed to PBB for 60 days calved normally with zero calf mortality and were successfully rebred. Milk production was not different from control animals. Birth weights of calves from dams exposed to 250 mg PBB/head/day were significantly greater than calves of dams exposed to 0 mg or 0.25 mg/head/day. PBB exposure of dams produced no detrimental effects on calves as indicated by clinical signs, clinicopathologic changes, or performance.
VACATIONS FOR CITY PEOPLE.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Endoscopic Complications
Authors: Stephen E. Silvis
Journal: JAMA (1976)

Esophagogastroduodenoscopy (211,410 examinations) had a complication rate of 1.3/1,000 cases. Duodenoscopy with cannulation was performed 3,884 times and had a complication rate of 21.6/1,000 examinations. Diagnostic coloscopy (25,298 examinations) had a complication rate of 3.4/1,000. Polypectomies during coloscopy (6,124 cases) had a complication rate of 23.3/1,000 cases. Esophageal dilations (13,139 cases) had a complication rate of 4.25 with mercury bougies, and in 9,431 cases metal olives produced a complication rate of 6.1/1,000 treatments. Dilation for achalasia in 1,224 patients produced a complication rate of 18.4/1,000 procedures. Peritoneoscopy (4,404 examinations) produced a complication rate of 5.4/1,000 patients. The value of these diagnostic and therapeutic procedures is now well established but must be weighed against a potential risk of complications. (<i>JAMA</i>235:928-930, 1976)
FDA Proposes to Require Financial Disclosure by Clinical Investigators
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Delayed Hemolytic Transfusion Reactions
Authors: Marion Worthington
Journal: JAMA (1978)

<h3>To the Editor.—</h3> The excellent article by Solanki and McCurdy (239:729, 1978) and letter by Kurtides (240:110, 1978) are deserving of our close attention, since we see more patients with a past history of blood transfusions. In our institution where we transfuse around 20,000 RBC products annually, three similar patients have come to our attention in the past three months. Renal impairment was fortunately not a problem, but the cause of the posttransfusion anemia was clinically unsuspected and was only elucidated by the blood bank technologists when further transfusions were requested. This lack of clinical suspicion was also noted by Mollison,<sup>1</sup>and we agree with the previous authors that these cases are being missed. Case 1 was a 30-year-old woman with dermatomyositis and steroidinduced diabetes admitted for repair of an esophageal rupture. Anti-E had been recorded previously, and E-negative compatible blood was transfused intraoperatively and postoperatively. Six days after
ANNUAL MEETING OF THE BRITISH MEDICAL ASSOCIATION: DERMATOLOGICAL SECTION
Journal: British Journal of Dermatology (1912)

British Journal of DermatologyVolume 24, Issue 9 p. 331-335 ANNUAL MEETING OF THE BRITISH MEDICAL ASSOCIATION: DERMATOLOGICAL SECTION First published: September 1912 https://doi.org/10.1111/j.1365-2133.1912.tb16745.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Volume24, Issue9September 1912Pages 331-335 RelatedInformation
ALLERGY AND THE PROTEOSE
Authors: G. H. Oriel
Journal: BMJ (1932)

<h3>Background</h3> Overuse of short-acting β2 agonists (SABA) may indicate poor asthma control and adverse health outcomes. Contemporary population-based data on use, risk factors and impact of SABA (over)use on asthma exacerbations and mortality are scarce, prompting initiation of the global SABINA (SABA use IN Asthma) programme. <h3>Methods</h3> By linking data from Swedish national registries, asthma patients aged 12–45 years with ≥2 collections of drugs for obstructive lung disease during 2006–2014 were included. SABA overuse defined as collection of &gt;2 SABA canisters in a one-year baseline period following inclusion. SABA use was grouped into 3–5, 6–10 and 11+ canisters/baseline-year. Cox regression was used to examine associations between SABA use and exacerbation (hospitalisations and/or OCS claims) and mortality. <h3>Results</h3> The analysis included 365 324 asthma patients (mean age 27.6 years; 55% women), average follow-up was 85.4 months. Some 30% overused SABA, with 21% collecting 3–5 canisters, 7% 6–10 and 2% 11+ canisters·year<sup>−1</sup>. Increasing number of collected SABA canisters was associated with increased risk of exacerbation: 3–5 (HR 1.26; [95% CI] 1.24–1.28); 6–10 (1.44; 1.41–1.46); and 11+ canisters (1.77; 1.72–1.83) compared to ≤2 canisters·year<sup>−1</sup>. Higher SABA use was associated with incrementally increased mortality risk (2564 deaths observed): 3–5 (HR 1.26; 95% CI 1.14–1.39); 6–10 (1.67; 1.49–1.87); and 11+ canisters (2.35, 2.02–2.72) compared to ≤2 canisters·year<sup>−1</sup>. <h3>Conclusion</h3> One-third of asthma patients in Sweden collected three or more SABA canisters annually. SABA overuse was associated with increased risks of exacerbation and mortality. These findings emphasise that monitoring of SABA usage should be key in improving asthma management.
Physicians and caries prevention. Results of a physician survey on preventive dental services
Authors: H. C. Gift
Journal: JAMA (1984)

Physicians are aware of and support selected caries preventive techniques involving fluoride, particularly community water fluoridation, fluoridating school water supplies, and the prescription of dietary fluoride supplements. Physicians are generally less informed about the relative worth of other caries preventive measures. The role of the practicing physician in the provision of caries prevention methods is a very active one, with physicians prescribing fluoride supplements, counseling on diet, and providing oral hygiene education. Children would be better served in caries prevention if the interest and initiative of the medical practitioners were encouraged and current information was made available to them. These findings represent the preliminary analysis of a mailed survey to a stratified, systematic sample of 2,000 physicians who treat child patients in the nation. (<i>JAMA</i>1984;252:1447-1448)
Polio Water
Authors: Daryl Jones
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Percutaneous radiographically guided catheter drainage of abdominal abscesses
Authors: E. vanSonnenberg
Journal: JAMA (1982)

We performed computed body tomography and ultrasound-guided percutaneous catheter drainage in 45 cases of abdominal abscess. Evacuation of the cavity was achieved in 40 cases (89%), eliminating the need for surgery in 34 patients. There were six recurrent abscesses, all due to fistulous communications or recurrent infected tumor. Major complications were a lacerated mesenteric vessel and a small-bowel fistula. Drainage catheters were removed an average of seven days after insertion. In many cases, guided percutaneous radiological drainage is an effective alternative to operative therapy, especially in severely ill patients. (<i>JAMA</i>1982;247:190-192)
Physicians hear about incontinence
Authors: P. Cotton
Journal: JAMA (1990)

MOST ADULTS in diapers do not need to be. Urinary incontinence is usually treatable, often without surgery. The problem, say experts, is getting primary care physicians to provide this care. That may change. Diaper manufacturers are starting to advise users to consult physicians, and government regulators are likely to get involved. But, for the moment, incontinence is of little interest to many physicians, says L. Lewis Wall, MD, director of the Bladder Function Clinic at Duke University Medical Center, Durham, NC. Physicians ask patients, "What do you expect at your age?" says Cheryl Gartley, president of the Simon Foundation, a support group that is based in Wilmette, Ill, a suburb of Chicago. Or they tell them to "wait until it becomes more of a problem," says Peter Sand, MD, director of urogynecology at Rush Medical College of Rush University in Chicago. Half the patients who are referred to him, he
A FEMALE ALEXIS ST. MARTIN
Journal: JAMA (1949)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Relation of Precordial and Orthogonal Leads
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sunset (Medusa)
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Stadium coronary care. A concept in emergency health care delivery
Authors: I. Kassanoff
Journal: JAMA (1972)

An emergency "life support station" was established at the Atlanta Stadium as part of a research program to elucidate the mechanism or precipitating events, or both, for the onset of myocardial infarction and sudden cardiac death, and to suggest appropriate therapeutic intervention. An emergency unit was also operated at Grant Field, the Georgia Tech football stadium. Anecdotal information in recent years had suggested that at least one acute event occurred at most stadium events with an attendance of more than 30,000 to 40,000 persons. However, Atlanta Stadium first aid station records for the years 1966 to 1969 showed only 20 reported episodes of apparent myocardial infarction, with or without sudden cardiac death. The research effort was thus designed to ascertain the incidence of apparent sudden cardiac death, to better define the clinical presentation and associated events, and to evaluate the feasibility of therapeutic intervention utilizing a well-staffed and well-equipped emergency
State medical discipline: defects and hindrances
Authors: D. G. Breaden
Journal: JAMA (1987)

In 1913, a year after the founding of the Federation of State Medical Boards of the United States, N. P. Colwell, MD, secretary of the American Medical Association's Council on Medical Education and an original fellow of the federation, writing in the first issue of the federation's quarterly, stressed the need of the state medical boards for improved medical practice acts, adequate funding and staffing, increased legal authority, and effective communication among themselves regarding unfit practitioners. The state boards, he said, "have striven valiantly against almost insurmountable obstacles to do their full duty.... The important thing is for [them] to recognize the defects... take stock of the hindrances, and altogether, through the Federation of State Medical Boards... press the campaign for betterment."<sup>1</sup> For 75 years, the federation has pressed the campaign for betterment in medical licensure and discipline. In its publications and educational programs, in every professional and public
Cancer Induction Following Single and Multiple Exposures to a Constant Amount of Vinyl Chloride Monomer
Authors: Robert M. Hehir, Bernard P. McNamara, Joseph McLaughlin, Donald A. Willigan, George Bierbower, Jerry F. Hardisty
Journal: Environmental Health Perspectives (1981)

Vinyl chloride monomer (VCM), already identified as a human animal carcinogen, was selected as a model agent to explore an area of concern for single and intermittent low level exposure. In traditional cancer bioassay, animals are repeatedly exposed over their lifespan to a dose of suspected chemical. In the current studies rats and mice were exposed in an inhalation chamber to single one-hour doses of VCM ranging from 50 to 50,000 ppm. A second group was given 10 one-hour exposures to 500 ppm or 100 one-hour exposures to 50 ppm of the same chemical. All animals were then observed for the remainder of their lives, generally 18-24 months. Moribund animals were euthanized, and survivors were sacrificed on schedule and their tissues examined for pathological changes. Specifically, the oncogenic study demonstrated dose related effects for single one-hour exposure of VCM at high levels, i.e., 5,000 and 50,000 ppm. These concentrations increased the incidence of pulmonary adenomas and carcinomas in mice. Repeated exposure of A/J mice to the same chemical at 500 ppm X 10 one-hour exposures also increased the incidence of pulmonary adenomas and carcinomas which are considered highly one-hour exposure, no significant increase in tumors was observed. Rats exposed to identical concentrations of VCM failed to elicit a tumorigenic response.
Heart disease risk factors and hormone use in postmenopausal women
Authors: E. Barrett-Connor
Journal: JAMA (1979)

A population of 1,496 women aged 55 to 74 years was studied for the distribution of heart disease risk factors in the presence or absence of postmenopausal estrogens. Current hormone use was reported by 39%. Hormone users were significantly slimmer than nonusers at all ages. After adjustment for the effect of obesity, hormone users had significantly lower mean levels of plasma cholesterol and higher mean levels of plasma triglycerides than nonusers. Blood pressure and fasting plasma glucose concentration tended to be lower among hormone users, although the differences were not statistically significant in all age groups. This article discusses the theoretical implications of these observations for cardiovascular disease mortality and contrasts them with the cancer risk of postmenopausal estrogen use. (<i>JAMA</i>241:2167-2169, 1979)