tbuckley/cabot-search huggingface dataset:
Acrylonitriles, a New Group of Ultraviolet Absorbing Compounds
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Dialysis in diabetics. A review of 44 patients
Authors: B. I. Chazan
Journal: JAMA (1969)

Our experience with peritioneal dialysis and hemodialysis in diabetic patients in the Joslin Clinic for the period 1959 to 1968 shows that 44 patients received dialysis; 32 for anasarca secondary to diabetic nephropathy and congestive heart failure, 7 for an acute exacerbation of chronic renal failure, and 5 for acute renal failure. Diffuse and nodular glomerulosclerosis was found in 19 of the 26 cases with autopsies or biopsies. Best results were obtained in three patients with acute tubular necrosis following diabetic acidosis, in one patient with glutethimide intoxication, and in two patients with chronic renal disease in whom therapy was maintained with long-term hemodialysis (one of whom had successful renal transplantation). Complications of induced hyperglycemia were easily regulated by frequent injections of small amounts of regular insulin. The presence of diabetes should not contraindicate dialysis, especially in those with acute renal failure.
Serotonin Metabolism in Patients with Liver Disease
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prostatic Cancer
Authors: WILLIAM D. DEWYS
Journal: Annals of Internal Medicine (1974)

Symposium1 October 1974Prostatic CancerWILLIAM D. DEWYS, M.D., F.A.C.P.WILLIAM D. DEWYS, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-81-4-553 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn 1972 the National Cancer Institute initiated organ site programs, by which grant support is directed to targeted research. In each organ site program, the planning, direction, coordination, and scientific administration are conducted at a headquarters institution other than the National Cancer Institute. A program director, with the aid of a working cadre of scientists, solicits research proposals, coordinates the review of applications, and recommends projects for funding to the National Cancer Institute. The proposals are judged on their scientific merit and conformity with the objectives of the organ site program.The prostatic organ site program sponsored a workshop on... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: The Medical School Northwestern University Chicago, Illinois PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByNeoplastic DiseasesOncology 1 October 1974Volume 81, Issue 4Page: 553-554KeywordsProstate cancerResearch designScientists Issue Published: 1 October 1974 PDF DownloadLoading ...
PROCEEDINGS OF THE MINNEAPOLIS SESSION
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical Surveillance of Exposed Persons after Exposure to PCBs, Chlorinated Dibenzodioxins and Dibenzofurans after PCB Transformer or Capacitor Incidents
Authors: Arnold Schecter
Journal: Environmental Health Perspectives (1985)

The panel discussion from the perspective of occupational medicine regarding appropriate medical surveillance after a PCB transformer or capacitor incident is reviewed. A thorough occupational medicine history and physical examination is stressed for any worker or other patient who may have been exposed. Appropriate laboratory tests, including complete blood count with differential, serum chemistries, serial blood PCB determinations, fat biopsy to estimate furan and dioxin levels, if indicated, pulmonary function tests, chest X-rays, urinalysis including porphyrin measurement, nerve conduction velocity testing and other tests are discussed. No consensus was reached on recommended length of medical followup. Because the field is rapidly changing, yearly updates of medical protocols are warranted. In addition, the need for surveillance to be conducted by specialists with training and experience in the fields of occupational medicine and nursing was emphasized. It was stressed that measuring the chemicals and their levels in soot and air and then comparing these with the patient's blood or fat levels, in the case of PCBs, furans and dioxins, is vital. It was noted that at present no modality of treatment is known to be clinically efficacious in removing PCBs, furans and dioxins from tissues or blood.
Hepatitis C and Cancer
Authors: Ala I. Sharara
Journal: Annals of Internal Medicine (1997)

Letters15 June 1997Hepatitis C and CancerAla I. Sharara, MD, Christine M. Hunt, MD, and John D. Hamilton, MDAla I. Sharara, MDDuke University Medical Center, Durham, NC 27710Search for more papers by this author, Christine M. Hunt, MDDuke University Medical Center, Durham, NC 27710Search for more papers by this author, and John D. Hamilton, MDDuke University Medical Center, Durham, NC 27710Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-126-12-199706150-00023 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Drs. Marinella and Moseley raise an interesting point about the possible association between non-Hodgkin B-cell lymphoma (NHL) and chronic HCV infection. As they mention, Ferri and colleagues [1] detected HCV viremia in 32% (16 of 50) of unselected patients with NHL compared with 3% of patients with Hodgkin lymphoma and 1.3% of healthy controls. At first glance, this marked discrepancy in the prevalence of HCV infection between patients with NHL and healthy controls cannot be ignored, but careful review of this study raises two concerns. First, blood exposure was reported in 10 of 50 patients, but the authors ...References1. Ferri C, Caracciolo F, Zignego AL, La Civita L, Monti M, Longombardo G, et al. Hepatitis C virus infection in patients with non-Hodgkin's lymphoma. Br J Haematol. 1994; 88:392-4. Google Scholar2. Conry-Cantilena C, VanRaden M, Gibble J, et al. Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus infection. N Engl J Med. 1996; 334:1691-6. Google Scholar3. Hill AB. The environment and disease: association or causation? Proc R Soc Med. 1965; 58:295-300. Google Scholar4. Parsonnet J, Friedman GD, Vandersteen DP, Chang Y, Vogelman JH, Orentreich N, et al. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med. 1991; 325:1127-31. Google Scholar5. Nomura A, Stemmermann GN, Chyou PH, Kato I, Perez-Perez GI, Blaser MJ. Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. N Engl J Med. 1991; 325:1132-6. Google Scholar Author, Article, and Disclosure InformationAffiliations: Duke University Medical Center, Durham, NC 27710 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 June 1997Volume 126, Issue 12Page: 1003KeywordsDrugsEpidemiologyHelicobacter pyloriHepatitis CHeterosexualsHodgkin lymphomaHuman sexual behaviorLymphomaMedical risk factorsViremia Issue Published: 15 June 1997 CopyrightCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF DownloadLoading ...
The Bubonic Plague in San Francisco
Journal: JAMA (2020)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Evaluation of euthyroid solitary. Autonomous nodule of the thyroid gland. Importance of scintillation scanning and thyrotropin-releasing hormone testing
Authors: M. Blum
Journal: JAMA (1982)

The euthyroid autonomous nodule of the thyroid may escape diagnosis if only the usual criterion of less than 50% suppression of radioactive iodine uptake (RAIU) after administration of liothyronine sodium is employed. This was the case in four patients who had thyrotoxic response to suppressive therapy, which had been given as a result of the improper conclusion that a nodule was hyperplastic, after the RAIU had fallen. We studied 95 patients with a solitary functioning nodule and found ten euthyroid persons (11 tests) in whom scintiscans showed persistent function in the nodule in spite of suppression of the RAIU by more than 50%. A thyrotropin-releasing hormone test demonstrated lack of thyroid-stimulating hormone responsiveness after administration of liothyronine, proving adequacy of the suppressive dose. Diagnosis of an autonomous nodule should not be excluded unless a scintiscan reveals that its function, in distinction to the rest of the gland, is curtailed by adequate suppression. (<i>JAMA</i>1982;247:1991-1993)
YOUR MANUSCRIPT, PLEASE.
Journal: JAMA (1891)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A phase Ib study of selumetinib (AZD6244, ARRY-142886) in combination with sorafenib in advanced hepatocellular carcinoma (HCC)
Authors: W.M. Tai, W.P. Yong, C. Lim, L.S. Low, C.K. Tham, T.S. Koh, Q.S. Ng, W.W. Wang, L.Z. Wang, S. Hartono, C.H. Thng, H. Huynh, K.T. Lim, H.C. Toh, B.C. Goh, S.P. Choo
Journal: Annals of Oncology (2017)

Ann Oncol (2016) 27 (12): 2210-2215. (doi:10.1093/annonc/mdw415) There is an error in an author name, S. Hartono was erroneously listed as S. Hartano. The publisher apologises for the error. A phase Ib study of selumetinib (AZD6244, ARRY-142886) in combination with sorafenib in advanced hepatocellular carcinoma (HCC)Annals of OncologyVol. 27Issue 12PreviewAngiogenesis and RAS/RAF/MEK/ERK pathway have been demonstrated to be relevant in hepatocellular carcinoma (HCC). Sorafenib, an oral multikinase inhibitor with activity against RAF kinase and vascular endothelial growth factor receptor-2, is approved for the treatment of advanced HCC. The therapeutic benefit however is modest. While displaying tumour growth inhibition and angiogenesis, sorafenib treatment in pre-clinical models exhibited up-regulation of pERK which may limit its anti-tumour activity. Full-Text PDF Open Archive
Sex Differences in Amphetamine-Induced Displacement of [&lt;char aid="99824119" id="sup"&gt;18&lt;/char&gt;F]Fallypride in Striatal and Extrastriatal Regions: A PET Study
Authors: Patrizia Riccardi
Journal: American Journal of Psychiatry (2006)

Objective: The authors examined gender differences in d -amphetamine-induced displacements of [ 18 F]fallypride in the striatal and extrastriatal brain regions and the correlations of these displacements with cognition and sensation seeking. Method: Six women and seven men underwent positron emission tomography (PET) with [ 18 F]fallypride before and after an oral dose of d -amphetamine. Percent displacements were calculated using regions of interest and parametric images of dopamine 2 (D 2 ) receptor binding potential. Results: Parametric images of dopamine release suggest that the female subjects had greater dopamine release than the male subjects in the right globus pallidus and right inferior frontal gyrus. Gender differences were observed in correlations of changes in cognition and sensation seeking with regional dopamine release. Conclusion: Findings revealed a greater dopamine release in women as well as gender differences in the relationship between regional dopamine release and sensation seeking and cognition.
Hospital Confinement
Authors: H. D. F. Fraser
Journal: BMJ (1957)

<h3>Background</h3> Type 2 diabetes is becoming more prevalent and its successful management relies on patients9 self-care behaviours. Measures focusing on patients9 perceptions can be effective behavioural interventions. <h3>Aim</h3> To gain insight into the perceptions of patients with diabetes, especially ideas of the illness course and perceived severity, and their impacts on self-care behaviour. <h3>Design of study</h3> Qualitative approach with in-depth patient interviews (<i>n</i> = 22) and seven focus groups (<i>n</i> = 53). <h3>Setting</h3> A rural town in Taiwan. <h3>Method</h3> The interview protocol was mainly derived from Kleinman9s explanatory model. Purposive sampling strategies of maximum variation were used. The transcript of the interviews was analysed with editing and immersion/crystallisation styles. <h3>Results</h3> Diabetes is regarded as an incurable, inevitably deteriorating disorder of sugar metabolism with many chronic complications. Patients thought that renal injury, followed by blindness, leg amputation, and poor peripheral circulation, were the most frequent complications. They also assessed their perceived severity of the disease at specific points in time through different indicators in their daily lives, such as sugar level, presence of complications, and medications used. Patients felt that these aspects progressed concurrently and that the illness course followed a unidimensional process. The ever-increasing doses of medication was considered by these patients to be a side-effect of the drugs taken. <h3>Conclusion</h3> Physicians should clarify with their patients that the risks of uraemia, blindness, and leg amputation are less prevalent than expected and that patients should pay more attention to cardiovascular complications. Certain oral hypoglycaemic agents may not cause a vicious cycle of ever-increasing doses of medication and the drugs that need to be taken should not be seen as indicators of severity but, rather, measures taken to prevent the diabetes becoming severe in the future.
Fibro-What?
Authors: Lawrence D. Grouse
Journal: JAMA (1980)

Fibronectins. Practitioners, academicians, and physicians-intraining should take notice of these proteins. The term "fibronectin" comes from Latin roots: fibro- from<i>fibra</i>, meaning fiber, -nectin from<i>nexus</i>, which means interconnection. A fibronectin is a fibrous, linking protein. Whereas plasma fibronectin is a circulating α<sub>2</sub>-glycoprotein that functions as an opsonin, cell-surface fibronectin mediates cellular adhesive interactions. Plasma fibronectin is a soluble version of cell-surface fibronectin. Both seem to be products of the same gene, although this has not been proved. The potential importance of fibronectins to clinicians is suggested by the following summary of fibronectin function. Reticuloendothelial system (RES)—mediated host-defense mechanisms are impaired in surgical and trauma patients and also in severely burned patients. Depression of RES function is also seen in patients with bacterial infection, neoplasia, and diseases of altered immunity. Such defects in host defense may result in sepsis and multiorgan failure. It is postulated that such failures
Deutsche Medizinische Wochenschrift, Stuttgart
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal