tbuckley/cabot-search huggingface dataset:
The prognosis in chronic bronchitis
Authors: G. L. Brinkman
Journal: JAMA (1966)

In 1958, 1,317 men working in the Detroit area were selected for study on the basis of two criteria: they were aged 40 to 65 years and working full-time. They were classified into four working groups: (1) no industrial exposure, (2) general industrial exposure, (3) 20 years of silica-dust exposure, and (4) 20 years of silica-dust exposure with roentgenogram evidence of silicosis. They were classified further as to whether they had chronic bronchitis, which was defined as a daily cough for six months, productive of at least a teaspoon of sputum a day. In 1964, the same group of men were reexamined using the same questionnaire as was used in 1958. A spirogram and chest roentgenogram were obtained as well. Altogether, 1,056 men were followed, which includes 123 men who died during this time. In this sample of the Detroit male population, the presence of chronic bronchitis did not have any significant adverse effect on health, working ability, or ventilation of these men over a six-year period.
THE ALLEGED PRESERVATION OF THE UNFIT
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Leçons sur l'alimentation: Physiologie, régimes.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cell biology/cytokines
Authors: V Vasilevski, M Krstevski, J Misevski, R Coleski, D Trajanovski, P Misevska, V Bidikov, K Stardelova, V Calovska, B Vladimirov
Journal: Gut (1994)

3rd UEGW Oslo 1994 A103 Hepatitis coma occurred in 16 (8%) patients in whom the sclerotherapy was performed once or twice.Eleven (68%) died.Another 13 pts died because of hemorrhagic shock, so the total mortality in this seria is 12%.Balloon tam- ponade was placed in 19 unsuccessful sclerotherapies.It was successful in 52%.Following complications have occurred: in 15 (7.6%) of pts: 1 fibrinoly- sis and 3 coagulum aspiration which were fatal.
Erratum for the Research Article: “The gut microbiota influences blood-brain barrier permeability in mice” by V. Braniste, M. Al-Asmakh, C. Kowal, F. Anuar, A. Abbaspour, M. Tóth, A. Korecka, N. Bakocevic, N. L. Guan, P. Kundu, B. Gulyás, C. Halldin, K. Hultenby, H. Nilsson, H. Hebert, B. T. Volpe, B. Diamond, S. Pettersson
Journal: Science Translational Medicine (2014)
Review: Erythropoiesis-stimulating agents increase mortality and venous thromboembolism in cancer-associated anemia
Authors: Stephan Thomé
Journal: Annals of Internal Medicine (2008)

Source Citation Bennett CL, Silver SM, Djulbegovic B, et al. Venous thromboembolism and mortality associated with recombinant erythropoietin and darbepoetin administration for the treatment of cancer-associated anemia. JAMA. 2008;299:914-24. [PMID: 18314434]
PITY THE TWISTING TONGUE
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Comparison of Long-Term Outcomes of Atrial Repair of Simple Transposition With Implications for a Late Arterial Switch Strategy
Authors: David Sarkar, Catherine Bull, Robert Yates, David Wright, Seamus Cullen, Marc Gewillig, Rebecca Clayton, Adelaide Tunstill, John Deanfield
Journal: Circulation (1999)

Background —We report the single-institution, long-term results of 358 patients with simple transposition of the great arteries surviving &gt;30 days after a Mustard (n=226, 1965 to 1980) or Senning (n=132, 1978 to 1992) procedure. Methods and Results —Outcome measures included late death, reintervention, ECG and ambulatory ECG rhythm, new arrhythmia, and functional status. Average follow-up was 13.4 (range 0.32 to 17.9) years for the Senning group and 11.7 (range 0.04 to 23.9) years for the Mustard group. The Senning group had a better survival rate at 5, 10, and 15 years (95% versus 86%, 94% versus 82%, and 94% versus 77%, respectively). In both groups, the majority of late deaths were sudden, without preceding ventricular dysfunction. Survival and survival free of reintervention were significantly better in the Senning group (relative risk [RR] 0.34, P =0.06 versus RR 0.39, P =0.027). Loss of sinus rhythm was comparable and unrelated to death. After era correction, the incidence of atrial flutter was similar and strongly associated with late death in both groups. Clinical systemic ventricular failure was uncommon, and at last follow-up, 92% of the Senning group and 89% of the Mustard group were in New York Heart Association class I. In a model exploring the implications of elective arterial switch conversion, this would only be beneficial if the hazard late after switch was markedly reduced and/or the hazard after the Senning procedure increased with time. Conclusions —Late outcomes after the Senning procedure are superior to those after the Mustard procedure. Both groups had late sudden deaths that were not associated with clinical systemic ventricular failure. Good functional status after the Senning procedure suggests that a strategy of elective switch conversion cannot be justified for patients with isolated transposition.
Domestic Abstracts
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review The Modern Therapeutics of Internal Diseases . An Introduction to Medical Practice. By A. P. Cawadias, O.B.E., M.D. (Durh. and Paris), M.R.C.P. (London). Formerly Chief of the Therapeutic Clinic of the University of Paris, etc. New York. William Wood and Company. 1931. 147 pages. Price $3.75.
Journal: New England Journal of Medicine (1932)
Correction: Early Childhood Developmental Status in Low- and Middle-Income Countries: National, Regional, and Global Prevalence Estimates Using Predictive Modelling
Authors: Dana Charles McCoy, Evan D. Peet, Majid Ezzati, Goodarz Danaei, Maureen M. Black, Christopher R. Sudfeld, Wafaie Fawzi, Günther Fink
Journal: PLoS Medicine (2017)

[This corrects the article DOI: 10.1371/journal.pmed.1002034.].
PTU-189 Are the current management strategies for T1/T2 N0 oesophageal cancer optimal?
Authors: J Evans, R Pande, D Beardsmore, D Corless, W Crisp, C Cheruvu
Journal: Gut (2012)

<h3>Introduction</h3> Currently patients with Stage 1 (T1/T2 N0) oesophageal cancer proceed straight to surgery; these patients have an expected 60%–90% 5 year survival. This staging is based on EUS (endoscopic ultrasound) and CT imaging, which are accurate in 90% and 70% for T stage respectively and 70% in N stage for EUS. However, reporting of postoperative histology reveals a significant proportion of these patients end up with locally advanced (T3 N1/0) disease, leading to a 5-year survival of 25%. The aim of this study is to assess the results based on the current UK protocols. <h3>Methods</h3> This study includes all patients who underwent an oesophagectomy over a 4-year period (2008–2011), focusing on those with T1/T2 N0 disease. After comprehensive staging which included endoscopy, EUS, CT and PET scanning all patients results were reviewed. Data on patients with T1/T2 N0 disease who went straight to surgery were analysed. The primary end points included a review of the number of patients who had a higher staging on post-operative histology and also the peri-operative mortality, morbidity and survival. <h3>Results</h3> 167 oesophagectomies were carried out during the study period in our institution, of which 26 (15.6%) were for preoperatively staged T1/T2 N0 disease (6 T1 and 20 T2). The mean age was 68 years and 18 (69.2%) of the patients were male. Ivor-Lewis oesophagectomies were performed on 23 patients, minimally invasive 3-stage procedures in 2 and 1 had a trans-hiatal operation. Post-operative histology indicated a higher stage of disease in 54% (14) of patients, 10 had a T3 lesion while 10 patients were noted to have nodal disease. One (3.8%) patient died on the 8th post-op day with bowel ischaemia and major or minor complications occurred in 11 (42%) of patients peri-operatively. Disease recurrence was seen in 4 (15.3%) patients at 15 to 18 months post-operatively, 3 (75%) of these had stage migration on histology to a higher stage and two have died. <h3>Conclusion</h3> Our study concludes that in patients with T1/2 N0 oesophageal cancer, despite the high specificity and sensitivity of both EUS and CT scan we still seem to have a large proportion of patients who are under staged and often offered curative operations, which appear to result in sub-optimal management leading to early recurrence and poorer long-term outcomes. Further studies are essential for accurate assessment of this stage of disease so that appropriate treatment strategies can be implemented for the management of oesophageal cancer. <h3>Competing interests</h3> None declared.
Prolactin Elevation With Ziprasidone
Authors: S. I. LUSSKIN
Journal: American Journal of Psychiatry (2004)

TO THE EDITOR: With the exception of risperidone, atypical antipsychotics have been thought to elevate prolactin only transiently (1-3).We report on a 41-year-old woman who developed clinically significant hyperprolactinemia while taking both risperidone and ziprasidone, which resolved with the introduction of quetiapine.Ms. A had a history of bipolar disorder and developed postpartum psychosis after her first child was born.She responded to lithium and risperidone.After the delivery of a second child while taking lithium, she again required risperidone (1.5 mg/day) for mood instability and obsessive ruminations about harming her baby.She had trace cogwheeling but no other extrapyramidal symptoms.She did not breast-feed, but she was amenorrheic for several months.Her prolactin level was 164.5 ng/ml.Brain magnetic resonance imaging showed no evidence of a pituitary microadenoma.Two weeks after she stopped taking risperidone, her prolactin level returned to normal, and she menstruated 1 week later.Because her ruminations returned, she was given oral ziprasidone, starting at 20 mg b.i.d., increased over 2 weeks to 60 mg b.i.d. for 3 weeks, then lowered to 100 mg at bedtime for 2 weeks because of sedation.Her ruminations disappeared, but she developed 1+ cogwheeling, tremor, and masked facies and did not menstruate; her prolactin level rose to 124 ng/ml.Ms. A was switched to quetiapine (400 mg/day) with resolution of extrapyramidal symptoms and a decrease in her prolactin level to 8.2 ng/ml.Her menses resumed within 3 weeks of stopping ziprasidone and remained regular for at least a year.Her prolactin level remained normal.
Clopidogrel and Long-term Outcomes After Drug-Eluting Stent Implantation
Authors: Alexis Matteau, Jacques LeLorier
Journal: JAMA (2007)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Intensive Care
Authors: Alvin M. Cotlar
Journal: JAMA (1976)

<i>Intensive Care</i>must be classified as one of those "good news-bad news" additions to the medical literature. The "good news" is a chapter of over 60 pages devoted to disturbance of fluid-electrolyte and acid-base balance. The "bad news" is that the chapter is so filled with complicated equations, graphs, and charts that one is not likely to extract much practical or even theoretical information from it. This same serious deficiency mars the value of the chapter on the "Physiology and Management of Acute Respiratory Failure in the Surgical Patient." This chapter begins with measurement of ventilation requirements and progresses to infinitely more complicated considerations. Somewhere in that material is worthwhile information for someone but certainly not the "average physician," nurses, and therapists referred to in the preface and for whom the book is supposedly written. As "good news," the book covers a great number of topics of interest to individuals
DIABETES INSIPIDUS FOLLOWING BRAIN LESIONS
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Digoxin Immune Fab Therapy for Digoxin Toxicity
Authors: Michael R. Ujhelyi
Journal: Annals of Internal Medicine (1994)

Letters1 February 1994Digoxin Immune Fab Therapy for Digoxin ToxicityMichael R. Ujhelyi, PharmD and Barbara J. Zarowitz, PharmDMichael R. Ujhelyi, PharmDMedical College of Georgia; Augusta, GA 30912Wayne State University; Detroit, MI 48202Search for more papers by this author and Barbara J. Zarowitz, PharmDMedical College of Georgia; Augusta, GA 30912Wayne State University; Detroit, MI 48202Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-120-3-199402010-00015 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We thank Dr. Phillips for his thoughtful comments. The clinical features of acute and chronic digoxin toxicity do differ. However, our purpose was not to study the clinical variables (chronicity, concomitant disease, and age) that affect how digoxin toxicity is manifested but to determine the disposition of free and total digoxin after Fab therapy and the value of free digoxin concentrations in monitoring patients. It is unlikely that whether digoxin toxicity was acute or chronic would influence the disposition of free and total digoxin after Fab therapy or the value of free digoxin concentrations. Stratification of the ...References1. Christensen RH, Studenberg SD, Beck-Davis S, Sedor FA. Digoxin-like immunoreactivity eliminated from serum by centrifugal ultrafiltration before fluorescence polarization immunoassay of digoxin. Clin Chem. 197; 33:606-8. Google Scholar2. Skogen WF, Rea MR, Valdes R Jr. Endogenous digoxin-like immunoreactive factors eliminated from serum samples by hydrophobic silica-gel and enzyme immunoassay. Clin Chem. 1987; 33:401-4. Google Scholar3. Frisolone J, Sylvia LM, Gelwan J, Pal S, Pellechia C. False-positive serum digoxin concentrations determined by three digoxin assays in assays in patients with liver disease. Clin Pharm. 198; 7:444-9. Google Scholar Author, Article, and Disclosure InformationAuthors: Michael R. Ujhelyi, PharmD; Barbara J. Zarowitz, PharmDAffiliations: Medical College of Georgia; Augusta, GA 30912Wayne State University; Detroit, MI 48202 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1994Volume 120, Issue 3Page: 247KeywordsAttentionCreatinineDrugsGlomerular filtration rateProteinsToxicityUltrafiltration ePublished: 15 August 2000 Issue Published: 1 February 1994 Copyright & PermissionsCopyright © 1994 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Sexual healing
Authors: Zosia Kmietowicz
Journal: BMJ (2007)

UK NEWS UK Biobank gets 10% response rate as it starts recruiting volunteers, p659 World NEWS US �u�ge bans use o�� ter�� �lig�t cigarette�� �orl��i�e, p65� US �u�ge bans use o�� ter�� �lig�t cigarette�� �orl��i�e
245. Repetitive Non-Invasive Monitoring of Herpes Simplex Virus-1 Thymidine Kinase (HSV1-tk) Expressing T-Cells Intravenously (i.v.) Infused into a Rhesus Macaque Using Positron Emission Tomography and Computed Tomography (PET-CT) with 18F-FEAU
Journal: Molecular Therapy (2009)
The breast cancer controversy
Authors: M. D. Decker
Journal: JAMA (1977)

<h3>To the Editor.—</h3> I am left rather confused by the article by Black et al concerning the apparent lack of impact of mammography on the stage of breast cancers coming to surgery (237:970, 1977). No indication is given as to what role mammography played in these cases other than the statements that "[since November 1974] the vast majority of breast lesions treated by the general surgeons have had preoperative mammography," whereas one surgeon (the specialist) had used it for ten years. Obviously, mammography cannot have an impact if it does not materially affect the selection of those who are to come to surgery. Usually, patients coming to surgeons have already been preselected, by the fact of referral, for the presence of clinical signs and symptoms, thus eliminating the opportunity for mammography to provide a precocious diagnosis. Even for those patients coming directly to the general surgeons or the specialist, there
EDP-305, a non-bile acid farnesoid X receptor (FXR) agonist, showed statistically significant improvements in liver biochemistry and hepatic steatosis in the phase 2a argon-1 study
Authors: Vlad Ratziu, Mary Rinella, Brent Tetri, Eric Lawitz, Douglas Denham, Zeid Kayali, Aasim Sheikh, Kris V. Kowdley, Taddese Desta, Magdy Elkhashab, Jeffery DeGrauw, Alaa Ahmad, Kajal Larson, Ty McClure, Nathalie Adda
Journal: Journal of Hepatology (2020)