tbuckley/cabot-search huggingface dataset:
The argon laser for cutaneous lesions
Authors: D. B. Apfelberg
Journal: JAMA (1981)

A summary of the pathophysiology and clinical use of the argon lser in the treatment of cutaneous lesions is presented. The nonionizing blue-green argon laser light is absorbed by pigment, is converted to heat, and selectively destroys specific cutaneous lesions with sparing of adjacent dermal appendages and healing of the laser wound with minimal scarring. Vascular lesions (port wine hemangioma, capillary-cavernous hemangioma, telangiectasia), inflammatory lesions (pyogenic granuloma), nevoid lesions, tattoo lesions, and a variety of miscellaneous lesions have been successfully treated. (<i>JAMA</i>1981;245:2073-2075)
Council on Physical Medicine
Journal: JAMA (1946)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Newspaper Reputation.
Authors: W. A. Pusey
Journal: JAMA (1903)

Chicago, March 24, 1903. In view of the surprising and, to some of us, painful newspaper publicity that characterized the now famous visit of Professor Lorenz to this country, the following clippings from the daily papers are of interest: "DR. MUELLER PERFORMS FOUR OPERATIONS. Dr. Frederick Mueller, the pupil of Dr. Lorenz, performed four of the most difficult operations for congenital dislocation of the hip, in Beth Israel Hospital to-day," etc., etc.—New York Letter, the<i>Chicago Tribune</i>, March 15, 1903. "LORENZ MACHINE IS USED SUCCESSFULLY. For the first time in this country the Lorenz machine has been used in an operation for hip disease. The operation was performed by Dr. Frederick Mueller, a pupil of Dr. Lorenz," etc., etc., etc.— New York Letter,<i>Chicago Record-Herald</i>, March 17, 1903. "DR. MUELLER IS BACK. ASSOCIATE OF DR. LORENZ WILL PRACTICE ORTHOPEDIC SURGERY HERE. TO REMAIN PERMANENTLY. NOTED VIENNA SURGEON WILL BECOME A CITIZEN
Alexander Anderson
Authors: Anderson Nettleship
Journal: New England Journal of Medicine (1954)

THE title Diarium Commentarium Vitae Alex. Anderson, Ann. 1793 is the beginning of a daily record that was to extend into the summer of 1799. Thus it was that Alexander Anderson, M.D., 1775–1870, labeled the first page of his diary, an account that was to reflect the formative years of this physician and engraver. It is a shame that an observer so accurate and objective did not record the last seventy-one years of his life. This man, known as the "Father of American Wood Engraving," had a keen view of life, which he imparted well in his writings. If he . . .
DIGESTIVE LEUKOCYTOSIS
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Neuro-ophthalmology
Authors: Jeffrey L. Bennett
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Decreased T cell infiltration and lymphocyte/dendritic cell/monocyte gene expression as well as increased Cyp3A5 mRNA predicts early recurrence of non-small cell lung cancer (NSCLC) following surgical resection
Authors: D. A. Potter, L. Li, S. Badve, K. Kesler, K. Rieger, N. Hanna, C. McDonald, H. Edenberg, L. H. Einhorn, R. Mitra
Journal: Journal of Clinical Oncology (2004)

7141
Investigating constipation.
Journal: BMJ (1980)

in our present armament is in treating infections caused by filamentous fungi, Aspergillus and the phycomycetes, and there is little evidence that the newer compounds are better than amphotericin or even as good.Most effort has been given to the development of the imidazoles-clotrimazole, miconazole, econazole, and keto- conazole.Clotrimazole has good activity against filamentous fungi as well as yeasts when given by mouth but it has proved too toxic to be marketed for systemic use.It is possibly the best topical antifungal agent now available (though in the dermatophyte infections systemic griseofulvin still has a paramount part to play).15The other imidazoles, including miconazole, still require further systemic evaluation, as many of the con- tributors to the symposium emphasised.Miconazole is effective in coccidioidomycosis, a rare condition in Britain.When it is given by mouth blood concentrations of the drug are low and variable, and it is not active by this route in generalised candidiasis, though this is implied in one of the papers.In systemic infection miconazole has to be given parenterally, and no clear impression has yet emerged of its efficacy.In view of the evidence from laboratory studies of antagonism when combined with amphotericin16 the two should not be used together.Ketoconazole when given by mouth seems to be absorbed more reliably but unfortunately its activity against Aspergillus species is variable and overall low.17Clearly much more work remains to be done on the imidazoles.In the mean time, the best prospect for systemic mycoses remains the early use of amphotericin by all appropriate routes, and for this we urgently need better techniques for early diagnosis.Finally, some fungal infections will not respond to antibiotics alone: prosthetic endocarditis, for example, requires combined treatment with reoperation.18
Evaluation of the Revised International Staging System (R-ISS) in an Independent Cohort of Unselected Patients with Multiple Myeloma
Authors: Efstathios Kastritis, Evangelos Terpos, Maria Gavriatopoulou, Magdalini Migkou, Evangelos Eleutherakis-Papaiakovou, Dimitrios Ziogas, Ioannis Panagiotidis, Despoina Fotiou, Dimitra Gika, Despoina Kalapanida, Eftychia Kafantari, Maria Roussou, Flora Zagouri, Stavroula Giannouli, Athanasios Zomas, Kostas Konstantopoulos, Meletios A. Dimopoulos
Journal: Blood (2015)
Evolving toward effective therapy for acute ischemic stroke
Authors: M. Fisher
Journal: JAMA (1993)

Acute ischemic stroke is a common, devastating disorder without beneficial therapy. Recent advances concerning the pathophysiology of ischemic brain injury have led to the development of rational pharmacological interventions. Thrombolytic and cytoprotective therapies may be useful and are being evaluated in clinical trials. The design of adequate clinical trials to evaluate these promising therapies has also evolved based on experience. Potential therapy for acute ischemic stroke must be assessed in a large number of patients who are given the intervention within hours of onset using a neurological scoring scale and a disability scale. Several new magnetic resonance imaging technologies are emerging that should allow the clinician to rapidly and accurately identify ischemic brain lesions and to evaluate cerebral perfusion. The availability of potentially efficacious therapies for ischemic stroke evaluated in well-designed clinical trials with magnetic resonance imaging technology, which can also assess therapeutic effects in vivo, should lead to the emergence of therapy to improve the outcome of patients with ischemic stroke in the near future. (<i>JAMA</i>. 1993;270:360-364)
PWE-082 Decrease in parietal cell density at squamo-columnar junction with increasing age in asymptomatic healthy volunteers
Authors: J P Seenan, M H Derakhshan, A A Wirz, A T Clarke, A W Kelman, J J Going, K E L McColl
Journal: Gut (2010)

<h3>Introduction</h3> The gastric cardia is an important site of pathology with a high incidence of inflammation, metaplasia and neoplasia. However the area is poorly understood and cardia mucosa may itself be pathological. Previous autopsy studies show a near absence of cardia epithelium in neonates and an increase in length with age. Aims: To<sup>1</sup> investigate whether parietal cell density in the columnar mucosa at the squamocolumnar junction (SCJ) changes with age and<sup>2</sup> determine the association of parietal cell density with distal oesophageal acid exposure. <h3>Methods</h3> 25 healthy volunteers (14 males, 5 <i>Helicobacter pylori</i> positive) were studied. Biopsies were taken from the macroscopic SCJ, 1 cm distal to the SCJ, gastric body and antrum. Biopsies were embedded in paraffin and 5-micron sections cut for immunohistochemistry. Parietal cells were stained and visualised using a standardised monoclonal anti-H+/K+ATPase antibody. Slides were digitally scanned and uploaded onto a slide server. An image analysis programme was used to quantify parietal cell density expressed as intracellular positive pixels. The average parietal cell density in a minimum of four sections of columnar mucosa per slide was reported as the percentage of the total cells per section. In 20 subjects pH studies were performed before and after a standardised meal. Acid exposure was calculated as per cent time pH&lt;4. Spearman9s σ correlation and Mann-Whitney U tests were used for analysis of non-parametric data. <h3>Results</h3> There was a significant negative correlation between age and parietal cell density in the columnar mucosa at the level of the SCJ (R=−0.530, p=0.008). There was no significant correlation between age and parietal cell density 1 cm distal to the SCJ (R=0.153, p=0.5), in the gastric body (R=0.386, p=0.08) or antrum (R=0.117, p=0.6). In the HP negative subgroup, parietal cell density at the SCJ of volunteers under 30 years old was significantly greater than those aged 30 years and over (6.8% vs 0.4%, p=0.05). In contrast, gastric body parietal cell density was lower in the younger group (30.0% vs 34.5%, p=0.019). There was no significant correlation between distal oesophageal acid exposure and parietal cell density at the SCJ (R=0.223, p=0.3). <h3>Conclusion</h3> Parietal cell density decreases with age in the columnar mucosa at the SCJ. This effect appears to be localised to the SCJ and is not seen 1 cm distal to this or within the stomach. There was no correlation between parietal cell density and acid exposure. These results support cardiac mucosa being acquired and due to mechanisms other than traditional gastro-oesophageal reflux.
PMO-222 Pre-operative endoscopy in bariatric surgery patients
Authors: G Bahra, A Desai, A Thillainayagam, A Ahmed
Journal: Gut (2012)

<h3>Introduction</h3> Some authors suggest the routine use of endoscopy in patients undergoing bariatric surgery in order to detect asymptomatic hiatal hernias, oesophagitis, and gastric ulcers. Our unit uses selective endoscopy. The current study analyses the indications and findings of upper GI endoscopy in pre-operative bariatric surgery patients. <h3>Methods</h3> A retrospective analysis of all bariatric surgery patients referred for Upper GI endoscopy at Charing Cross Hospital from 1 January 2009 to 30 October 2011. During this time period, 1093 bariatric surgery cases were performed. These consisted of 542 laparoscopic gastric bypasses, 220 laparoscopic gastric band insertions, 223 laparoscopic sleeve gastrectomies and 108 revisional bariatric procedures. The Endoscopy units9 electronic database of oesophagogastroduodenoscopies (OGDs) performed in that time period was analysed to determine how many bariatric surgery patients underwent OGDs pre-operatively and for what indication and with what result. Further sub-analysis was performed for each operation type. <h3>Results</h3> 147 OGDs were done on a total of 116 bariatric surgical patients, with 23 patients having had more than one OGD each. Of these 147 OGDs 44 were pre-operative. 13 (29.5%) OGD referrals were made to investigate anaemia, 12 (27.3%) for pre-surgical screening to investigate existing symptoms of gastric ulceration, and 9 (20.5%) to investigate abdominal pain. The remaining referrals were made for interventional gastric balloon insertions and removals (6=13.6%) and to investigate symptoms of reflux (3=6.8%) and dysphagia (1=2.3%). The majority of patients (50%) were referred prior to having a roux-en-y gastric bypass operation. Most of the pre-operative OGD findings were normal (16=36.4%), but gastritis (6=13.6%), hiatal hernias (6=13.6%), gastric ulceration (2=4.5%), oesophagitis (1=2.3%) and duodenitis (1=2.3%) were noted. Of the 13 patients referred with anaemia, 9 (69.2%) had normal mucosa on OGD, but of the 12 patients who had pre-surgical screening 7 (58.3%) were found to have abnormalities, including a fundic gland polyp and antral erosions. <h3>Conclusion</h3> Using a selective referral process, only 4% of all bariatric surgery cases performed required preoperative endoscopy. The commonest indication for OGD preoperatively was anaemia and the commonest pathology found was mucosal inflammation (gastritis, oesophagitis and duodenitis). <h3>Competing interests</h3> None declared.
Inadequate oxygenation and ventilation using the esophageal gastric tube airway in the prehospital setting
Authors: P. S. Auerbach
Journal: JAMA (1983)

In a prospective study to evaluate the respiratory effectiveness of the esophageal gastric tube airway (EGTA) in the prehospital setting, we analyzed arterial blood samples from 43 victims of out-of-hospital cardiopulmonary arrest managed with the EGTA. Five minutes after emergency department endotracheal intubation, arterial blood gas analysis was repeated for comparison. During EGTA ventilation, the mean arterial Po<sub>2</sub>measured 83.6 ±110.4 mm Hg; endotracheal intubation increased the mean Po<sub>2</sub>to 189 ±167.5 mm Hg. During EGTA ventilation, the mean arterial Pco<sub>2</sub>measured 77.1±34 mm Hg; endotracheal intubation decreased the mean Pco<sub>2</sub>to 57.8 ±34.4 mm Hg. We conclude that endotracheal intubation remains the procedure of choice for airway management in the victim of cardiopulmonary arrest. (<i>JAMA</i>1983;250:3067-3071)
Error in Figure
Journal: JAMA (2018)

Sylvia K. Plevritis, PhD; Diego Munoz, MS, PhD; Allison W. Kurian, MD, MS; Natasha K. Stout, PhD; Oguzhan Alagoz, PhD; Aimee M. Near, MPH; Sandra J. Lee, ScD; Jeroen J. van den Broek, MS; Xuelin Huang, PhD; Clyde B. Schechter, MA, MD; Brian L. Sprague, PhD; Juhee Song, PhD; Harry J. de Koning, MD, PhD; Amy Trentham-Dietz, MS, PhD; Nicolien T. van Ravesteyn, PhD; Ronald Gangnon, PhD; Young Chandler, MS, MPH, DrPH; Yisheng Li, PhD; Cong Xu, PhD; Mehmet Ali Ergun, PhD; Hui Huang, MS; Donald A. Berry, PhD; Jeanne S. Mandelblatt, PhD
Pain Guidelines Encourage Vigilance
Authors: B. Vastag
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE CAUSE OF WHOOPING COUGH.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Childhood Sibling Relationships as a Predictor of Major Depression in Adulthood: A 30-Year Prospective Study
Authors: Robert Waldinger
Journal: American Journal of Psychiatry (2007)

Objective: The authors examined the quality of sibling relationships in childhood as a predictor of major depression in adulthood. Method: Study subjects were 229 men selected for mental and physical health and followed from ages 20 through 50 and beyond as part of a study of adult psychosocial development. Data were obtained from interviews with participants and their parents at intake and from follow-up interviews and self-report questionnaires completed by participants at regular intervals. These data were used to rate the quality of relationships with siblings, the quality of parenting received in childhood, and family history of depression as well as the occurrence, by age 50, of major depression, alcoholism, and use of mood-altering drugs (tranquilizers, sleeping pills, and stimulants). Results: Poorer relationships with siblings prior to age 20 and a family history of depression independently predicted both the occurrence of major depression and the frequency of use of mood-altering drugs by age 50, even after adjustment for the quality of childhood relationships with parents. Poor relationships with parents in childhood did not predict the occurrence of depression by age 50 when family history of depression and the quality of relationships with siblings were taken into account. Quality of sibling relationships and family history of depression did not predict later alcohol abuse or dependence. Conclusions: Poor sibling relationships in childhood may be an important and specific predictor of major depression in adulthood. Further study of links between childhood sibling relationships and adult depression is warranted.
Bullet Boy
Authors: Piyal Sen
Journal: BMJ (2005)

Directed by Saul Dibb UK release date: 8 April 2005 www.bulletboy.net/ Rating: ![Graphic][1]</img>![Graphic][2]</img>![Graphic][3]</img>![Graphic][4]</img> Bullet Boy tells the story of Ricky, a young black male, struggling to escape his criminal past, peer group, and most importantly his sense of absolute loyalty. This loyalty leads him to pay back a debt owed to a close friend, despite warnings from his girlfriend, mother, and a leader of the local church, himself a man with a past. The result is an escalating pattern of violence between … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif [3]: /embed/inline-graphic-3.gif [4]: /embed/inline-graphic-4.gif
Journal of the Society for Gynecologic Investigation
Authors: Joan S. Zenan
Journal: JAMA (1995)

The<i>Journal of the Society for Gynecologic Investigation (JSGI)</i>, a peer-reviewed quarterly periodical, serves as the official publication of the society. The journal pursues the mission of "the advancement of knowledge in reproductive biology." Each issue contains a review article and 10 to 20 original reports. Manuscripts must conform to the uniform requirements for manuscripts submitted to biomedical journals. The editors intend to have manuscripts peer reviewed anonymously. Conflict-of-interest issues are resolved between the editor and author to determine proper disclosure. Interestingly, there is no policy for letters to the editor, a desirable feature that facilitates scholarly dialogue among medical scientists. Most articles have statements of approval from institutional research committees or of compliance with animal care standards where applicable. Bimonthly publication, editorial comment, and position papers are options for future development. Each original report begins with a structured abstract. Thorough descriptions of experimental methods enable readers to repeat tests