tbuckley/cabot-search huggingface dataset:
The Organization of the Medical Profession.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medicine, Learning
Authors: DeWitt C. Baldwin, Jr
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
North American Society for Cardiac Radiology—1982 Postgraduate Course
Journal: JNCI Journal of the National Cancer Institute (1982)

Journal Article North American Society for Cardiac Radiology—1982 Postgraduate Course Get access JNCI: Journal of the National Cancer Institute, Volume 68, Issue 1, January 1982, Page 175, https://doi.org/10.1093/jnci/68.1.175-c Published: 01 January 1982
Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus
Authors: Veronique Chauvet, Xin Tian, Herve Husson, David H. Grimm, Tong Wang, Thomas Hieseberger, Peter Igarashi, Anton M. Bennett, Oxana Ibraghimov-Beskrovnaya, Stefan Somlo, Michael J. Caplan
Journal: Journal of Clinical Investigation (2005)
Possible role of soyabean therapy in isolated platelet factor 3 (PF3) availability defect
Authors: R. Saxena, V.P. Choudhry, D.K. Mishra, R. Kashyap, S. Mohanty
Journal: American Journal of Hematology (1999)

Fulminant Brain Lymphoid Infiltration in a Patient With Chronic Lymphocytic LeukemiaTo the Editor: Symptomatic involvement of the central nervous system (CNS) in chronic lymphocytic leukemia (CLL) is very rare.We present a TABLE I. Drugs Associated With Lymphadenopathy* Phenytoin Carbamazepine Para-amino salicylic
Erratum
Journal: New England Journal of Medicine (1937)

coordination of health services in Africa were discussed, as well.The previous conference, in 1934, had proved so fruitful that that of 1935 was called to carry on the work.The advantages of personal discussion were again so manifest in 1935 that a resolution was passed recommending that other conferences organ- ized along similar lines should be held in the future.As to yellow fever, it has been learned recently by means of surveys that this disease has been endemic for many years in certain "silent" regions of the Amazon valley in Brazil, Bolivia, Peru and Colombia.These regions are termed "silent" be- cause cases of yellow fever had not been recognized in them.It is believed, nevertheless, that deaths from yellow fever must have occurred there, even though Aedes aegypti is not known in some of these regions.Differences in the age and sex distribution of this so-called "jungle yellow fever", which is not transmitted by Aedes, and the ordinary type were pointed out.Vaccination against yellow fever was advocated by colonial medical advisers for all whites proceeding to territories where yellow fever occurred.Many other interesting questions relating to yellow fever were discussed.The report on plague deals with this disease in Africa and in Madagascar.In the Union of South Africa and in neighboring countries to the north and west of it, the incidence of human plague is determined by epizootics in wild rodents.Malaria still occupies a foremost place, if not the foremost, as a cause of death among the aboriginal
Long-term survival after cisplatin-based induction chemotherapy and radiotherapy for nasopharyngeal carcinoma: A pooled data analysis of two phase III trials
Authors: D. T. T. Chua, J. Ma, J. S. T. Sham
Journal: Journal of Clinical Oncology (2004)

5524 Background: To evaluate the long-term treatment outcome in patients with advanced stage nasopharyngeal carcinoma (NPC) treated by cisplatin-based induction chemotherapy and radiotherapy (CRT) versus radiotherapy alone (RT). Methods: The updated records of two previously reported phase III studies (the Asian-Oceania Clinical Oncology Association trial and the Guangzhou trial). testing the benefit of adding induction chemotherapy to radiotherapy in NPC were reviewed and the data were pooled together for analysis. A total of 784 patients were included for analysis, with equal number of patients in both the CRT and RT arms. The induction chemotherapy consisting of 2–3 cycles of cisplatin 100 mg/m2 day 1, bleomycin 10 mg/m2 day 1 & 5, and fluorouracil 800 mg/m2 day 1–5, or cisplatin 60 mg/m2 day 1 and epirubicin 110 mg/m2 day 1. Radiotherapy was given to the nasopharynx and neck using megavoltage radiation, with a median dose of 70 Gy. Treatment compliance was 92.6% in the CRT arm and 98% in the RT arm. The median follow-up time for surviving patients was 67 months. Analysis was done by intention to treat. Results: The addition of induction chemotherapy to radiotherapy was associated with a decrease in relapse by 14.3% and cancer deaths by 12.9% at 5 years. The 5-year relapse-free survival rate was 50.9% in the CRT arm and 42.7% in the RT arm (p=0.014), and the 5-year disease-specific survival rate was 63.5% in the CRT arm and 58.1% in the RT arm (p=0.029). The median disease-specific survival was not yet reached in the CRT arm and it was 82 months in the RT arm. The incidence of loco-regional failure and distant metastases were reduced by 18.3% and 13.3% at 5 years respectively with induction chemotherapy. There was no significant difference in the failure patterns between the 2 arms. Conclusions: The addition of cisplatin-based induction chemotherapy to radiotherapy was associated with a modest but significant improvement in survival in advanced stage NPC. No significant financial relationships to disclose.
Transactions of the Texas State Medical Association.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DISCUSSION: Ankle Instability
Journal: British Journal of Sports Medicine (1980)

RENSTROM started the discussion on instability of the knee, the mechanism of stabilising ligaments and bones, and the necessity of ligament strength rather than muscle contraction to offset the stresses imposed by sport.Muscles are active stabilisers and protective to a certain extent and the ligaments are passive and thereby the main stabilisers.There are differences between active stability, depending upon quadriceps and hamstrings contraction, and passive stability depending upon ligaments.Johnson (1978) showed that reflex activation time was shorter for ligament than for muscle, the latter assisting in stabilisation after ligaments have borne the initial strain.J. P. S. ENGLAND said that provided the cruciate and capsular ligaments are intact, however, the knee may appear stable functionally, despite collateral ligament damage.J. G. P. WILLIAMS amplified this idea in assuming that the muscles were in a flaccid state when Johnson performed his experiments, but as muscle is a dynamic structure in the alert athlete it will be in tension before stress is applied.The trained athlete develops movement patterns that should enable muscles to react in time, provided training is adequate and undue fatique avoided.A sprinter may be able to run 100 M with a complete tear of the medial collateral ligaments, but be unable to make a sudden turn.For these rotational stresses a dynamic stabilisation such as a pes anserinus transplant, or a static one by ligament repair is necessary.A Principal feature of instability of any joint is proprioceptive feedback, and failure of this interferes with the protective action of muscles, and leads to injury.J. P. S. ENGLAND.A knee can be functionally stable even with a complete rupture of the anterior cruciate ligament.P. RENSTROM mentioned Ljungqvist's (1979) series of about 80 athletes including many jumpers with partial rupture of the infrapatellar ligament often located to the posterior aspect of the ligament.J. G. P. WILLIAMS noted that the histology of these lesions was identical with his own series of achilles tendon injuries.T. DURKIN raised the possibility of cruciate repair or replacement with carbon fibre filaments, now being pioneered by Jenkins in Cardiff.J. P. S. ENGLAND stated that this work was still in early stages, and doubted whether the technique had been perfected sufficiently for the stresses imposed by sport.J. G. P. WILLIAMS discussed various techniques of cruciate ligament repair, including Erikson's operation for anterior cruciate tears, a modification of Lamb's operation.J. P. S. ENGLAND commented that a problem in Britain, was the difficulty in getting suitable patients early enough, compared with the two or three weeks reported by Renstrom..
THE STIMULUS OF SUNLIGHT.
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
David Clark
Journal: BMJ (2006)

served in the Royal Army Medical Corps in Normandy, Belgium, and Rhodesia before joining his brother in general practice in Bellshill in industrial Lanarkshire.After retirement in 1978 he did locum work.He was chairman of Lanarkshire Medical Committee for 12 years.In addition to an avid interest in politics, sport, crosswords, and puddings, he supplied family, friends and neighbours with plants annually, and grew show chrysanthemums, winning many prizes locally and nationally.He was chairman of the Scottish Chrysanthemum and Dahlia Society for many years.David survived cancer three times.
Postmenopausal Estrogen Replacement Therapy and the Risk for Blood Clots: A Review from the U.S. Preventive Services Task Force
Journal: Annals of Internal Medicine (2002)

Summaries for Patients7 May 2002Postmenopausal Estrogen Replacement Therapy and the Risk for Blood Clots: A Review from the U.S. Preventive Services Task ForceSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-136-9-200205070-00005 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?After a woman stops menstruating (menopause), her body produces much less of the hormone estrogen. Lower estrogen levels can cause uncomfortable symptoms, such as hot flashes, and put women at risk for thinning of the bones (osteoporosis) and possibly some other medical conditions. Use of the hormone estrogen after menopause (postmenopausal estrogen replacement therapy) can decrease the uncomfortable symptoms of menopause and prevent osteoporosis. Hormone replacement therapy may also decrease the risk for some other conditions, such as heart disease and Alzheimer disease, but these effects are not ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Postmenopausal Estrogen Replacement and Risk for Venous Thromboembolism: A Systematic Review and Meta-Analysis for the U.S. Preventive Services Task Force.” It is in the 7 May 2002 issue of Annals of Internal Medicine (volume 136, pages 680-690). The authors are J Miller, BKS Chan, and HD Nelson.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoPostmenopausal Estrogen Replacement and Risk for Venous Thromboembolism Jill Miller , Benjamin K.S. Chan , and Heidi D. Nelson Metrics Cited byHormone replacement therapy in postmenopausal women increases the likelihood for implant survival 7 May 2002Volume 136, Issue 9Page: I-42KeywordsCardiovascular therapyEstrogen replacement therapyEstrogensHealth careHormone replacement therapyMenopauseOsteoporosisPulmonary embolismThromboembolismThrombosis ePublished: 7 May 2002 Issue Published: 7 May 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Erratum: Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease: What We Know and Can Do for Our Patients
Authors: Robinder Khemani, Nadir Yehya, Anoopindar Bhalla, Neal Thomas, Christopher Newth
Journal: American Journal of Respiratory and Critical Care Medicine (2018)

harm.To definitively prove this and change practice, we should first "walk" with a randomized controlled trial comparing usual care with PEEP/FI O 2 grid-based management.We agree that this PEEP/FI O 2 table may not be the final best approach to PEEP management, but these more individualized methods should be compared with PEEP/FI O 2 grid-based management to determine whether the additional complexity required by these more individualized approaches, which are not consistently used in clinical PARDS practice, translates into improved clinical outcomes.
Correction: C reactive protein impairs adaptive immunity in immune cells of patients with melanoma
Authors: Stefan Nierkens, Tonke K Raaijmakers, Renske J E van den Bijgaart, Martijn H den Brok, Melissa Wassink, Annemarie de Graaf, Jori A Wagenaars, Marleen Ansems, Gert Jan Scheffer, Gosse J Adema
Journal: Journal for ImmunoTherapy of Cancer (2020)
Diagnosis of perforated enterocystoplasty
Authors: E. Fontaine, R. Leaver, C. R J Woodhouse
Journal: Journal of the Royal Society of Medicine (2003)

In the operation of enterocystoplasty, now widely practised, segments of bowel are used to augment or replace the urinary bladder. An occasional complication is perforation, and this may present in non-specialist settings. We investigated the management of spontaneous perforations among 264 patients with enterocystoplasty followed by one surgeon for 2-18 years. Patients’ charts were examined for data on presentation, diagnosis and treatment. 10 patients had thirteen perforations; data were available for nine perforations in 9 patients. Mean time from enterocystoplasty to perforation was 45 months. Presentation was shoulder pain in 1 and abdominal pain (with or without fever) in 8. Perforation was diagnosed without delay in 3, but the initial diagnosis was urinary tract infection in 4 and small-bowel obstruction in 2. Ultrasound was the most useful investigation being diagnostic in 6 of 7 cases; contrast cystography showed a leak in only 2 of the 6 patients in whom it was performed. Treatment was successful in 8 cases (surgery 6; percutaneous drainage 2); 1 patient, who remained undiagnosed, was treated medically and died. Patients with enterocystoplasty need to be educated about this potentially lethal complication, so that they can alert non-specialist clinicians to what may have happened. In any patient with enterocystoplasty who reports abdominal pain or shoulder pain, perforation has to be ruled out.
Mesenchymal stem cells regulate hepatocytes excessive autophagy and apoptosis through miR-125b/TRAF6 pathway in acute-on-chronic liver failure
Authors: Dengna Lin, Bingliang Lin, Jing Zhang, Jing Xiong, Juan Gao, Weizhen Weng, Jun-Feng Chen, Shao Quan Zhang
Journal: Journal of Hepatology (2020)
Abstract 3295: Systematic <i>in vivo</i> analysis of PI3K pathway aberrations in a mouse model for invasive lobular carcinoma
Authors: Martine H. van Miltenburg, Sjoerd Klarenbeek, Tanya Braumuller, Linda Henneman, Rahmen Bin Ali, Ivo Huijbers, Paul Krimpenfort, Anton Berns, Jos Jonkers
Journal: Cancer Research (2012)

Abstract Invasive lobular carcinoma (ILC) is a form of breast cancer that develops in the milk-producing glands (lobules) of the breast. ILC is an aggressive form of breast cancer due to its ability to spread to other parts of the body, both by bloodstream as well as lymphatic system. One of the key features found in ILC is loss of E-cadherin, encoding CDH1. Mammary-gland specific deletion of E-cadherin does not lead to tumour formation indicating that other factors are involved in the induction of ILC. Indeed, combined tissue-specific inactivation of E-cadherin and p53 induces development of invasive and metastatic mammary tumours resembling human ILC. However, a limitation of the current conditional mouse models is that human ILCs rarely contain p53 mutations. In contrast, PI3K pathway mutations are frequently found in human ILCs. Currently we are developing novel mouse ILC models to systematically examine the contribution of PI3K pathway components such as PIK3CA, AKT and PTEN to ILC development. To reduce time spent on generating a genetically engineered mouse (GEM) tumour cohort expressing three or more transgenes we set-up embryonic stem (ES) cell derivation and targeting of ES cells from validated GEM models, the so-called GEMM-ESC strategy. WapCre-Cdh1F/F ES cells targeted with PIK3CA or AKT mutants are now being used to generate the elaborate PI3K pathway tumour cohort. These advanced models will allow us to study the role of the PI3K pathway in the pathogenesis of ILC. Moreover, we can use these advanced mouse models which recapitulate key hallmarks of human ILC to perform refined and realistic preclinical prevention and intervention studies for ILC. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 3295. doi:1538-7445.AM2012-3295
Transactions of the Medical Society of Virginia.
Journal: JAMA (1898)

This volume covers the proceedings of the twenty-eighth annual meeting of the Society, held at Hot Springs, Va., Aug. 31 and Sept. 1 and 2, 1897, and contains twenty-two papers presented to the Society, general discussions, obituaries, list of presidents and vice-presidents, with statistic data of value to the physician. An appendix contains a biographic register of Fellows of the Society.
Long-term survival of repeat hepatic resection and radiofrequency ablation for patients with recurrent hepatocellular carcinoma: a multicentric study
Authors: Jian-Hong Zhong, Yan-Yan Wang, Wan-Guang Zhang, Anthony Wing-Hung Chan, Charing C.N. Chong, Matteo Serenari, Ning Peng, Tao Huang, Shi-Dong Lu, Zhi-Yin Liang, Bao-Cai Xing, Matteo Cescon, Tian-Qi Tliu, Lin Li, Le-Qun Li, Matteo Ravaioli, Jacopo Neri, Alessandro Cucchetti, Philip Johnson, Bang-De Xiang
Journal: Journal of Hepatology (2020)