tbuckley/cabot-search huggingface dataset:
Handbook of Anatomy.
Journal: JAMA (1910)

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Omitted Financial Support Statement.
Journal: JAMA (1997)

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Advanced Cases of Coal Workers' Pneumoconiosis—Two Counties, Virginia, 2006
Journal: JAMA (2006)

This report describes 11 newly identified cases of advanced coal workers' pneumoconiosis (CWP), including progressive massive fibrosis (PMF), in working coal miners from Lee and Wise counties in southwestern Virginia. PMF is a disabling and potentially fatal form of CWP, an occupational lung disease caused by the inhalation of coal mine dust. The continuing occurrence of advanced forms of CWP emphasizes the importance of comprehensive measures to control coal mine dust effectively and reduce the potential for inhalation exposures in coal mining.
A new, easily inserted catheter for intermittent peritoneal dialysis
Authors: S. Kupfer
Journal: JAMA (1967)

A new flexible catheter for peritoneal dialysis has been used over a 15-month period in 15 patients for a total of 100 days of dialysis. The catheter is easy to insert, and its insertion causes little or no trauma. For the most part, the catheter has been reintroduced without serious clinical or technical difficulties for each intermittent course of treatment in patients with either acute or chronic uremia. The risk of intra-abdominal infection is thereby reduced. Details of the procedure for peritoneal dialysis and the composition of the fluids generally used for managing various clinical states associated with uremia are outlined.
Combined checkpoint immunotherapy and cytotoxic chemotherapy: Further results from a phase Ib/II trial of pembrolizumab and docetaxel or gemcitabine in patients with advanced or metastatic urothelial cancer.
Authors: Mamta Parikh, Chong-xian Pan, Laurel Beckett, Yueju Li, Daniel Robles, Christina DeVisser, Primo Lara
Journal: Journal of Clinical Oncology (2018)

4541 Background: We previously reported tolerability of pembrolizumab plus either docetaxel or gemcitabine in platinum-treated metastatic urothelial cancer patients (pts), given the hypothesis that chemotherapy might enhance tumoral neoantigen expression and modulate immunogenicity of tumor cells, potentially enhancing the response to anti-PD-1 therapy. Herein we report further results from an expansion cohort. Methods: Eligible pts had Zubrod PS 0-1, adequate end-organ function, with progression following up to 2 prior lines of chemotherapy (at least one platinum based). Patients were treated with pembrolizumab 200 mg IV on D1 q3weeks plus either docetaxel 75 mg/m2 IV on D1 (Arm A) or gemcitabine 1000 mg/m2 IV on D1 & D8 (Arm B). Primary endpoint was safety; secondary endpoints were overall response rate (RR) and progression free-survival (PFS). Results: A total of 20 pts have enrolled, 9 in Arm A, 11 in Arm B. Mean age was 66 (range 31-84). Most common AEs ≥ Grade 3 were hyponatremia (8/20), anemia (5/20), fatigue (5/20), neutropenia (4/20), leukopenia (4/20) acute kidney injury (3/20), hypophosphatemia (3/20). There were no treatment-related deaths; 13 died from disease progression. In total, 1 pt had complete response (CR), 5 pts had partial responses (PR), 3 pts had minor responses (MR), 4 had stable disease (SD), and 7 progressed; overall RR was 45% and Disease Control Rate (DCR) was 65%. Arm A had overall RR of 44%, DCR 56%. Arm B had overall RR of 45%, DCR 73%. Median PFS (overall, Arm A & Arm B) were 7, 13.3, and 5.9 months. Conclusions: The combination of pembrolizumab with either docetaxel or gemcitabine is tolerated with no unexpected adverse effects, with evidence of efficacy. Expanded cohorts continue to enroll. Clinical trial information: NCT02437370.
Annals Roy College Surgeons of England, London
Journal: JAMA (1964)

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Data Error in Text in: Laser Photocoagulation and Intravitreal Injection of Triamcinolone for Retinal Vein Occlusions
Authors: Arnaud Saj, Shahar Arzy, Patrik Vuilleumier
Journal: JAMA (2009)

Comment.The findings of this case, suggesting neglect of conversion origin, indicate that such symptoms may not simply reflect symbolic behavior or beliefs (as postulated by Freud and Breuer 1 ) but appear to affect cognitive processes that can be selectively disconnected from conscious awareness, as observed for neglect after organic lesions. 1,2The fMRI data support this hypothesis by showing preserved activation of parietal cortex (normally recruited by line bisection), 3 together with increases in anterior cingulate that might relate to attention, 2 conflict between instructions and intentions, 1,4 and inhibitory processes specifically related to the production of conversion. 5utomatic shifts of attention in both directions (indicating spontaneous and symmetric responses to lateralized stimuli), combined with no shift of attention when judging centrally bisected stimuli, point to involuntary control of attentional processes in the parietal cortex, consistent with impaired access to conscious control.This study highlights the existence of neglect symptoms due to conversion, demonstrates specific functional neuroanatomical correlates, and confirms and extends previous evidence for increased cingulate activity during conversion with other purely motor symptoms. 5,6
Thermography
Authors: Irwin M. Freundlich
Journal: New England Journal of Medicine (1972)

Breast thermography is both misunderstood and overestimated by physicians and laymen alike. Since a unilateral increase in heat emanation is a nonspecific response to a variety of breast lesions, it is not surprising that thermography (i.e. the pictorial representation of infrared emanations from the skin) does not succeed in separating benign from malignant tumors in symptomatic females.1 The goal of the thermography-mammography tandem and the primary role of both examinations is not the differentiation of benign and malignant masses, but the detection of nonpalpable carcinoma. For the general population, therefore, it may well become an effective screening technic. It should . . .
Rory Nicol
Authors: D. Nicol
Journal: BMJ (2010)

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DOUBLE TUBAL PREGNANCY: ONE TWINS
Journal: JAMA (1920)

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Plato's View of the Physician
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Measles
Authors: Bharath Balu, Eliot N. Mostow
Journal: JAMA Dermatology (2019)

MeaslesWhat Is Measles?Measles is an infection caused by the measles virus.It spreads through coughing, sneezing, and contact with contaminated surfaces.It usually causes coldlike symptoms and a rash, but sometimes it can be fatal. Risk FactorsAnyone not given the measles vaccine or who has received only 1 dose can get measles.Children who are too young to be vaccinated have a high risk of infection.Unvaccinated people who travel internationally, attend college, or work in a hospital are also at increased risk.People with vitamin A deficiency may have a more severe case.
Abstract 4427: Electrocardiographic Left Ventricular Hypertrophy Predicts Long Term Fatal Outcomes in Elderly Hypertensives Despite Diuretic-Based Antihypertensive Treatment: 14-Year Follow-Up of the Systolic Hypertension in the Elderly Program (SHEP)
Authors: Tudor Vagaonescu, Alan C Wilson, John B Kostis
Journal: Circulation (2008)

Background: To assess if diuretic-based antihypertensive treatment improves long term fatal (cardiovascular) outcomes in the elderly with isolated systolic hypertension (ISH) and ECG documented left ventricular hypertrophy (LVH). Methods: Retrospective analysis of the SHEP database of 4,736 patients age ≥60 years and ISH and subsequent vital status ascertainment by matching to the National Death Index. Results: 348 subjects (7.35%) of SHEP participants had ECG documented LVH at baseline. Subjects with LVH had at baseline: higher SBP and pulse pressure (p&lt;0.0001), carotid bruits (13% vs. 7%, p&lt;0.0001) and previous history of myocardial infarction (8% vs. 4%, p=.0008) when compared with participants without LVH. There were no significant differences with regard to age, sex, heart rate, body mass index, smoking and alcohol use, previous history of stroke, diabetes, angina, and assignment to treatment or placebo group. Over 14.3 years (mean) of follow up subjects with baseline LVH experienced significantly more all cause mortality (51% vs. 40%, p&lt;0.0001) and cardiovascular death (24% vs. 19%, p=0.002) than participants without baseline LVH. In the group of participants with LVH at baseline active treatment of hypertension did not decrease all cause mortality (51% vs. 50%, NS) or cardiovascular death (26% vs. 24%, NS). There was no statistically significant interaction between LVH and the assignment to treatment (antihypertensive medication vs. placebo). In a multivariable analysis, the adjusted Cox hazard ratio of developing any fatal outcome in the LVH group was 1.181 (95% CI 1.005–1.387, p=0.043) after adjusting for age, sex, race, history of myocardial infarction, diabetes, alcohol smoking status, education, blood pressure, and assignment to treatment or to placebo group. Conclusion: In the elderly with ISH the presence of LVH documented by ECG increased the risk for long term fatal outcomes despite treatment with diuretic-based antihypertensive therapy. Although active treatment lowered risk in the SHEP study, treated participants with LVH had a higher risk for fatal outcomes than treated subjects without LVH.
Shelter
Authors: Susan Dix Lyons
Journal: JAMA (2021)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chenic acid for gall stones.
Journal: BMJ (1978)

impairing absorption and causing protein loss from necrosis and ulceration.With so many factors that may contribute to the pathogenesis of cachexia in the individual patient their relative importance may be difficult to determine.The presence of nutritional depletion may be detected very simply: a recent loss of 1000 of total body weight, a serum albumin concentration of less than 34 g/l, and a negative reaction to a battery of skin test antigens.Patients depleted on the basis of those criteria require aggressive nutritional repletion (through the gut or by in- fusion) with the aim of preventing death from debility or infection, reducing the incidence of wound dehiscence, enhancing the immune response, and extending the limits of tolerance of cancer treatment.
PARENTAL VITAMIN D DEFICIENCY DURING PREGNANCY IS ASSOCIATED WITH INCREASED BLOOD PRESSURE IN OFFSPRING VIA PANX1 HYPERMETHYLATION
Authors: Laura Meems, Hasan Mahmud, Hendrik Buikema, Jorg Tost, Sven Michel, Janny Takens, Rikst Nynke Verkaik-Schakel, Inge Vreeswijk-Baudoin, Irene Mateo Leach, Torsten Plosch, Rudolf De Boer
Journal: Journal of the American College of Cardiology (2016)
Association Badge.
Authors: A. A. Noyes
Journal: JAMA (1896)

North Minneapolis, Minn., April 7, 1896. <h3>To the Editor:</h3> —In the last number of ourJournalI notice a short article from Dr. Blaisdell on the "Association Badge." I have spoken of it a number of times during the last few years, asking myself and others of the Association members: What had become of our badge? It has been so long since it was decided and I think voted upon in theAssociationthat we were to have it that I have really forgotten at what meeting it was acted upon, whether Detroit, Chicago, Washington, Richmond, or where. I think Dr. N. S. Davis, of Chicago, introduced the subject, but am not sure. I have grown old since that time, now nearly 74 years, and I feel as though if I am to see a badge it will have to be coming along very soon. A great many of our
Mastoids Roentgenologically Considered.
Journal: JAMA (1930)

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Flu Clues
Authors: M. J. Friedrich
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TRAUMATIC PNEUMONIA
Authors: C. M. Beadnell
Journal: BMJ (1905)

ACUTE inflammation of the lungs bearing a definite rnlation to the application of pbysical violence is, I think, of sufficient rarity to warrant publication.The following are the notes of such a case recently under my care.History.-Arthur M., an A.B. in H.M. navy, age 20, while on duty in a steamboat at 7 p.m, May 28tb, tripped and fell, striking his left arm and left side of chest violently against the gunwale.When he returred on board the d6p6t ship he mtade no complaint, and " turned in " without assistance.Admission to Sick Bay.-At 7 a.m. the following day, feeling very faint and sitiff, he lay down in the gallJ-v until 7.30 a.m., when he was brought to the sick bay.He then complained of hpadache, inability to move his left arm, vague pains over the left side of the chest, and a desire to pass water.His skin was hot and dry, his cheeks flushed, and his bladder distended.Temperature was 1040 F., pulse 120, respirations 28.He was put to bed, 30 oz. of clear nonalbuminous urine were drawn off by catheter, an enema was administered, and a diaphoretic prescribed thrice daily.No pbysical signs were observed in the heart or lungs.
Linguistic Ability in Early Life and Alzheimer Disease in Late Life
Authors: Henry N. Massie
Journal: JAMA (1996)

<h3>To the Editor.</h3> —I read with great interest the article by Dr Snowdon and colleagues.<sup>1</sup>They found that nuns whose autobiographies had high idea density and grammatical complexity when they were young were less likely to develop Alzheimer disease in later years. However, the analysis of writing samples appears to have a potentially important omission. Of the 2 detailed samples of writing provided, that of sister A who developed Alzheimer disease and that of sister B who had not developed Alzheimer disease at 80 years of age (published in their entirety in the New<i>York Times</i><sup>2</sup>), sister A's writing contains no expressions of emotion and sister B's writing contains 5 direct expressions of emotion and 2 metaphorical expressions of strong feeling. It is possible that it is not merely cognitive complexity of thought at a young age that correlates with later health, but that having the ability to