Thrombolytic Therapy
Authors: STANLEY L. SCHRIER
Journal: Annals of Internal Medicine (1980)

Editorial Notes1 October 1980Thrombolytic TherapySTANLEY L. SCHRIER, M.D.STANLEY L. SCHRIER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-93-4-629 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe recent report in this journal of the National Institutes of Health (NIH) Consensus Development Conference on the use of thrombolytic therapy (1) and the accompanying editorial note by Victor Marder (2) have suggested that fibrinolytic agents may not be used often enough. Dr. Marder argues that the hazards of fibrinolytic agents have been misinterpreted and quotes the hematology section of theMedical Knowledge Self-Assessment Program (MKSAP) V Syllabus(3), which states that the use of fibrinolytic agents "carries a 40% to 50% risk of serious hemorrhage." As the chairman of the MKSAP V committee that wrote the hematology section...References1. Thrombolytic therapy in thrombosis: A National Institutes of Health Consensus Development Conference. Ann Intern Med. 1980;93:141-4. LinkGoogle Scholar2. MARDER V. Are we using fibrinolytic agents often enough? Ann Intern Med. 1980;93:136-7. Editorial. LinkGoogle Scholar3. Pharmacology of heparin and the fibrinolytic agents: Hematology. In: Medical Knowledge Self-Assessment Program V Syylabus Part 2. Philadelphia: American College of Physicians: 1979:150. Google Scholar4. The Urokinase Pulmonary Embolism Trial: A national cooperative study. Circulation. 1973:47(suppl):11-1-108. (American Heart Association Monograph Number 39.) Google Scholar5. Streptase (streptokinase) Circular. Somerville, New Jersey: HoechstRoussel Pharmaceuticals, Inc.; 1977. Google Scholar6. MARDER V. The use of thrombolytic agents: choice of patient, drug administration, laboratory monitoring. Ann Intern Med. 1979;90:802-8. LinkGoogle Scholar7. DUCKERTMÜLLERNYMAN FGD. Treatment of deep vein thrombosis with streptokinase. Br Med J 1975;1:479-81. CrossrefMedlineGoogle Scholar8. BELLMEEK WA. Guidelines for the use of thrombolytic agents. N Eng J Med. 1979;301:1266-70. CrossrefMedlineGoogle Scholar9. KISTNERSPARKUHL RM. Surgery in acute and chronic venous disease. Surgery. 1979;85:31-43. MedlineGoogle Scholar10. VERSTRAETE M. Biochemical and clinical aspects of thrombolysis. Semin Hematol. 1978;15:35-54. MedlineGoogle Scholar11. SEAMANCOMMONROSCH AHJ. Deep vein thrombosis treated with streptokinase or heparin. Angiology. 1976;27:549-56. CrossrefMedlineGoogle Scholar12. COMMONSEAMANROSCHPORTERDOTTER HAJJC. Deep vein thrombosis treated with streptokinase or heparin. Angiology. 1976;27:549-56. CrossrefMedlineGoogle Scholar13. COON W. Epidemiology of venous thromboembolism. Ann Surg. 1977;186:149-64. CrossrefMedlineGoogle Scholar14. COONWILLISKELLER WPJ. Venous thromboembolism and other venous diseases in the Tecumseh Community Health Study. Circulation. 1973;48:839-46. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Division of Hematology Department of Medicine Stanford University School of Medicine Stanford, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byStreptokinase Therapy in the Routine Management of Deep Venous Thrombosis in the Lower ExtremitiesPooled analyses of randomized trials of streptokinase and heparin in phlebographically documented acute deep venous thrombosis 1 October 1980Volume 93, Issue 4Page: 629-630KeywordsHematology and oncologyHemorrhage ePublished: 1 December 2008 Issue Published: 1 October 1980 PDF downloadLoading ...