tbuckley/cabot-search huggingface dataset:
THE SURGICAL TREATMENT OF GASTRIC AND DUODENAL ULCER AND ITS RESULTS.
Authors: WILLIAM J. MAYO
Journal: JAMA (1906)

quarters of an inch above the greater curvature, giving an opening somewhat oblique from above down, right to left not less than two inches in length (Fig. 1). The torn edges of the transverse meso-colon are attached to the suture line by three mattress sutures in such manner as to leave a perfectly smooth peritoneal border, the ragged and fatty margins being tucked up underneath so as not to cause adhesions. It is important that the distal end of the jejunum be attached as it naturally lies that it may at once drop to the left and posteriorly in its normal anatomical position. The operation thus briefly outlined has a nominal mortality. We had but 1 death in 135 "no loop" operations. The anterior method preferably with a Murphy button or McGraw ligature, is occasionally demanded by reason of posterior adhesions or abnormalities in the mesocolon or duodeno-jejunal juncture; but
Pulmonary toxicity of antineoplastic drugs
Authors: G. Batist
Journal: JAMA (1981)

Pulmonary toxicity caused by antineoplastic drugs is becoming a more frequently recognized entity, and the number of drugs known or suspected of causing this disease is steadily increasing. In general, the initial clinical appearance includes both constitutional signs of malaise and fever, as well as pulmonary complaints. Some clinical signs may suggest a particular drug as the cause. The pathological condition also is generally nonspecific, but some clues may be present histologically that help define the causal agent. This is a review of the antineoplastic drugs that are associated with pulmonary toxicity. Clinical, laboratory, and pathological data are presented as useful information for practicing physicians. Although therapeutic maneuvers are limited, these are discussed with regard to each drug. (<i>JAMA</i>1981;246:1449-1453)
Ocular Therapeutics.
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Lidocaine Dose Error.
Journal: JAMA (1975)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Query necessity, cost-effectiveness of IVP to evaluate prostatism
Authors: J. Elliott
Journal: JAMA (1979)

Ask any urologist. Intravenous pyelography (IVP), like kissing your spouse good-bye in the morning or brushing your teeth before going to bed, goes hand in hand with transurethral prostatectomy (TURP). The most commonly performed urologic procedure in America, TURP until now has been almost invariably preceded by IVP for detection of any pathological condition in the upper urinary tract. But a new study conducted at the University of Kentucky Medical Center in Lexington by Department of Urology chairman J. William McRoberts, MD, and urology residents Daniel L. Bauer, MD, and Robert W. Garrison, MD, indicates that in most cases IVP before TURP is probably not necessary. "When we reviewed a specially selected group of 601 patients who had had routine IVP prior to transurethral resections," explained Bauer, "we found positive results so seldom that we believe the test is not indicated and certainly not cost-effective." However, Bauer was quick to
Abstract 2306: Transcriptional and post-transcriptional upregulation of p27 mediates growth inhibition of isorhapontigenin/ISO on human bladder cancer cells
Authors: Jiheng Xu, Jingxia Li, Chuanshu Huang, Haishan Huang, Guosong Jiang
Journal: Cancer Research (2018)

Abstract Our recent studies have demonstrated that Isorhapontigenin (ISO), a new derivative isolated from the Chinese herb Gnetum Cleistostachyum, effectively induces cell-cycle arrest at the G0/G1 phase and inhibits anchorage-independent cell growth through the miR-137/Sp1/cyclin D1 axis in human muscle invasive bladder cancer cells both in vitro and in vivo. Herein, we found that treatment of muscle invasive bladder cancer cells with ISO resulted in a significant upregulation of p27, a key cyclin-dependent kinase inhibitor. Importantly, knockdown of p27 caused a decline in the ISO-induced G0-G1 growth arrest and reversed ISO suppression of anchorage-independent growth in bladder cancer cells. Mechanistic studies revealed that ISO promoted p27 expression at mRNA transcription level through increasing direct binding of FOXO1 to its promoter, while knockdown of FOXO1 attenuated ISO inhibition of cell growth. On the other hand, ISO upregulated the 3'UTR activity of p27, which was accompanied by a reduction of miR-182 expression. In line with these observations, ectopic expression of miR-182 significantly blocked p27 3'UTR activity, whereas mutation of the miR-182 binding site at p27 mRNA 3'UTR effectively reversed this inhibition. Accordingly, ectopic expression of miR-182 also attenuated ISO upregulation of p27 expression and impaired ISO inhibition of cancer cell growth. Our results not only provide novel insight into understanding of the underlying mechanism related to regulation of muscle invasive bladder cancer cell growth, but also identify new roles and mechanisms underlying ISO inhibition of the growth of human bladder cancer cells. Citation Format: Jiheng Xu, Jingxia Li, Chuanshu Huang, Haishan Huang, Guosong Jiang. Transcriptional and post-transcriptional upregulation of p27 mediates growth inhibition of isorhapontigenin/ISO on human bladder cancer cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 2306.
F-18 Fluorodeoxyglucose (FDG) PET and Indium-111 SPECT scans to track the biodistribution of macrophage-activated killer (MAK) cells linked with MDX-H210 in patients with epithelial ovarian cancer
Authors: H. M. Prince, L. R. Mileshkin, D. Wall, M. Thompson, J. Wong, D. Rischin, E. Lau, P. Eu, F. Auzelle, R. Hicks
Journal: Journal of Clinical Oncology (2004)

2595
Using Medication To Prevent Breast Cancer: Recommendations from the United States Preventive Services Task Force
Journal: Annals of Internal Medicine (2002)

Summaries for Patients2 July 2002Using Medication To Prevent Breast Cancer: Recommendations from the United States Preventive Services Task ForceSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-1-200207020-00005 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the United States Preventive Services Task Force?The United States Preventive Services Task Force (USPSTF) is a group of physicians and other health care experts that reviews published research and makes recommendations about preventive health care.What is the problem and what is known about it so far?Breast cancer is a common type of cancer among women in the United States. Despite improvements in early detection and treatment, about 39,600 American women will die of breast cancer in 2002. Chemoprevention is a strategy for reducing the risk for cancer (“prevention”) by taking drugs (“chemo”). The drug tamoxifen ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full reports titled “Chemoprevention of Breast Cancer: Recommendations and Rationale” and “Chemoprevention of Breast Cancer: A Summary of the Evidence for the U.S. Preventive Services Task Force.” They are in the 2 July 2002 issue of Annals of Internal Medicine (volume 137, pages 56-58 and pages 59-67). The first report was written by the U.S. Preventive Services Task Force; the second report was written by LS Kinsinger, R Harris, SH Woolf, HC Sox, and KN Lohr.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoChemoprevention of Breast Cancer: Recommendations and RationaleChemoprevention of Breast Cancer: A Summary of the Evidence for the U.S. Preventive Services Task Force Linda S. Kinsinger , Russell Harris , Steven H. Woolf , Harold C. Sox , and Kathleen N. Lohr Metrics Cited byTamoxifen-associated vasculitis in a breast cancer patientPeut-on prévenir chimiquement le cancer du sein en 2003 ? 2 July 2002Volume 137, Issue 1Page: I-62KeywordsBreast cancerCancer preventionChemopreventionDrugsHealth careMedical risk factorsPreventive medicineStrokeThrombosisUterus ePublished: 2 July 2002 Issue Published: 2 July 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
An assessment of the different tools used to assess treatments in pyoderma gangrenosum
Journal: British Journal of Dermatology (2020)

Pyoderma gangrenosum (PG) is a rare, inflammatory skin disease that results in painful sores and is difficult to heal. In the U.K., PG occurs in 3‐10 people per million every year. Due to its rarity, there is a lack of validated tools (meaning methods, and also called ‘instruments’, that have been validated, to show they are effective) for assessing the effectiveness of treatments, resulting in the absence of a uniform standard of care.
Response
Authors: SUSAN S. DEVESA, WILLIAM J. BLOT, JOSEPH F. FRAUMENI
Journal: JNCI Journal of the National Cancer Institute (1991)

Journal Article Response Get access SUSAN S. DEVESA, SUSAN S. DEVESA Search for other works by this author on: Oxford Academic PubMed Google Scholar WILLIAM J. BLOT, WILLIAM J. BLOT Search for other works by this author on: Oxford Academic PubMed Google Scholar JOSEPH F. FRAUMENI JOSEPH F. FRAUMENI Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 83, Issue 5, 6 March 1991, Pages 369–370, https://doi.org/10.1093/jnci/83.5.369 Published: 06 March 1991
Parkinson's disease: new drugs help but no cure on the horizon
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contents page
Authors: James Russell, Lawrence Barsalou, J Staddon, Marcel Brass, Jan Derrfuss, Birte Forstmann, D Yves Von Cramon, Ruth Millikan, Thomas Metzinger, Alvin Goldman, Natalie Sebanz, Rebecca Saxe, Edward Bowden, Mark Jung-Beeman, Jessica Fleck, John Kounios, Aaron Seitz, Takeo Watanabe, Stanislas Dehaene, Laurent Cohen, Mariano Sigman, Fabien Vinckier, Jennifer Hay, R Harald Baayen, Patrick Cavanagh, George Trendsin, Julian Ogilvie, Katie Forsythe, Manager Moulton
Journal: Trends in Cognitive Sciences (2005)
THE DECLINE OF AN OLD AMENITY
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Trauma Systems
Authors: Marcus Bassett
Journal: JAMA (1989)

<h3>To the Editor.—</h3> The article entitled "Trauma Systems: Current Status— Future Challenges"<sup>1</sup>affirms that trauma systems and trauma centers reduce mortality from major trauma in the areas where they are used. The fact that progress in implementing regional trauma systems has been slow, and in most states nonexistent, is also demonstrated. However, I do not agree that the major barriers are economic. First, the authors assert that failure to implement regional trauma systems would open the door to outside control and regulation. Yet they also advocate legislation to define the authority to implement a regional trauma plan and to provide management structure and financial resources. This appears to relinquish control of the system from the very beginning. Physicians, especially those outside the level I trauma center, would have little, if any, input into the system. Second, this is an elitist system. To be a level I trauma center, a
Outbreak of Salmonella enteritidis Infection Associated With Consumption of Raw Shell Eggs
Journal: JAMA (1992)

Salmonella enteritidis (SE) is the most frequently reported Salmonella serotype in the United States. From January through December 1991, state health departments reported 66 outbreaks of SE in the United States to CDC. This report describes an SE outbreak associated with consumption of raw shell eggs and underscores the necessity of adequately cooking shell eggs.
Elegy
Authors: Emma Samelson-Jones
Journal: Annals of Internal Medicine (2010)

On Being a Doctor16 March 2010ElegyEmma Samelson-Jones, MDEmma Samelson-Jones, MDFrom Columbia University, New York, NY 10025.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-152-6-201003160-00012 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail I first met Ms. Bryan on a Thursday at 1 a.m. Three months later, I would look up her autopsy report on the computer. I would scroll down the screen searching for an explanation for her death as memories replayed themselves: her lying in the intensive care unit after her brain biopsy, unresponsive, the guilt flooding my cheeks as I thought of our conversation the previous day. She: “I'm afraid.” Me: “Routine procedure.” I would remember leading a group of 25 white-coated physicians into her room and the 3 hours she spent with a spinal needle in her back, asking ... Author, Article, and Disclosure InformationAffiliations: From Columbia University, New York, NY 10025.Corresponding Author: Emma Samelson-Jones, MD, 201 West 108th Street, Apt 55, New York, NY 10025. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 16 March 2010Volume 152, Issue 6Page: 398-399KeywordsAutopsyBiopsyBrainComputersDeceptionMemoryNeurologyNeurosurgerySteroidsThorax ePublished: 16 March 2010 Issue Published: 16 March 2010 Copyright & PermissionsCopyright © 2010 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Errors in Figure, Byline, and Author Affiliations
Authors: Julie Dreier, Yuelian Sun, Jakob Christensen, Julie Werenberg Dreier, Christopher Thompson, Karl Alcover
Journal: JAMA Pediatrics (2020)

The affiliation of Dr Thompson was reported as Peds AI Clinic and has been corrected to Peds AI.Finally, 2 graphs in the Figure were lacking the footnote
LETTER FROM LONDON.
Authors: None G. O. M.
Journal: JAMA (1891)

(FROM OUR OWN CORRESPONDENT.) In several instances of late pneumonia has been most successfully treated by large doses of digitalis. By some medical men the expectant method of treating pneumonia is thought to be not only irrational, but even dangerous, and that the assumption that there is a definite cycle of progress in pneumonia is not warranted, and from experience obtained at the leading London hospitals, the disease may be jugulated or cut short by an energetic, rational mode of treatment, especially if the method is inaugurated at the onset of the disease, and that, finally, the claim is supported that the treatment of pneumonia with large doses of digitalis promises better results than those obtainable by any other mode of procedure. Dr. Steele has drawn attention to some useful precautions in the extraction of broken needles. He says that it is most unpleasant, after cutting and probing with the
Congenital Malformations in Offspring of Alloxan-Diabetic Mice
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
These Migraines
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A throughway is different from a pathway
Authors: J. E. Chapman
Journal: JAMA (1986)

A study by Signer and Crowley<sup>1</sup>appearing in this issue ofThe Journaladdresses important matters related to medical training. The students described seek clinical instruction in the United States to complement or finish their program of medical education while enrolled in foreign medical schools, primarily in the Caribbean Basin or Mexico. These circumstances are of concern because they differ from the usual entry pathway to clinical experience and differ from the educational relationships common to most US medical schools. The requirements for enrollment, examination of the credentials, and evaluation of the performance of these students are variable. This raises important questions regarding readiness and outcome. Also in question is the comparability of credit derived from such experiences with the credit given students enrolled in an approved program of medical education evaluated by the Liaison Committee on Medical Education (LCME). Approval by the LCME requires the examination of admissions