tbuckley/cabot-search huggingface dataset:
THE UNITED STATES PUBLIC HEALTH AND MARINE-HOSPITAL SERVICE.PART I. A HISTORICAL SKETCH.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Lethal host-versus-graft disease and hypereosinophilia in the absence of MHC I-T-cell interactions
Authors: Jérôme D. Coudert, Gilles Foucras, Cécile Demur, Christiane Coureau, Catherine Mazerolles, Georges Delsol, Philippe Druet, Jean-Charles Guéry
Journal: Journal of Clinical Investigation (2000)
A Medical Mystery
Authors: Gerhard Kurlemann, Otfried Debus
Journal: New England Journal of Medicine (2000)

Figure 1 What do these photographs of the eye of a 19-year-old man show, and what systemic disorder does the man have? Figure 1 What do these photographs of the eye of a 19-year-old man show, and what systemic disorder does the man have? Gerhard Kurlemann, M.D.Otfried Debus, M.D.University of Münster, D-48129 Münster, Germany
Benign intracranial hypertension.
Authors: M E McAlindon, P J Toghill, T Jaspan, G Lennox
Journal: Gut (1994)

<h3>Abstract</h3> Overexploitation can lead to a rapid collapse of consumers that is difficult to reverse if ecosystems exhibit alternative stable states. However, support for this phenomenon remains predominantly limited to simple models, whereas food webs might dissipate the feedback loops that create alternative stable states through species-specific demography and interactions. Here we develop a general model of consumer-resource interactions with two types of processes: either specialized feedbacks where individual resources become unpalatable at high abundance or aggregate feedbacks where overall resource abundance reduces consumer recruitment. We then quantify how the degree of interconnectedness and species differences in demography affect the potential for either feedback to produce consumer- or resource-dominated food web states. Our results highlight that such alternative stable states could be more likely to happen when aggregate feedbacks or lower species differences increase redundancy in species contributions to persistence of the consumer guild. Conversely, specialized palatability feedbacks with distinctive species roles in guild persistence reduce the potential for alternative states but increase the likelihood that losing vulnerable consumers cascades into a food web collapse at low stress levels, a fragility absent in few-species models. Altogether, we suggest that species heterogeneity has a greater impact on whether feedbacks prevent consumer recovery than on the presence of many-species collapses.
Myocardial Stress Studies: From Anesthesia To ECGs
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE PATHOLOGY OF OVERDOSAGE WITH PARATHYROID HORMONE
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hexachlorophene Bathing in Control of Skin Infections
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 4323: 1,25-Dihydroxyvitamin D3 inhibits oral squamous cell carcinoma cell growth via microRNA regulation
Authors: Heba Said Ismail Hussein, Wei Wang, Liang Shan, Karl Thompson, Kareem Washington, Gihane Madkour, Xinbin Gu
Journal: Cancer Research (2019)

Abstract Objective: Oral squamous cell carcinomas (OSCC) is one of top ten cancers lead to death in USA. This study focused on the impacts of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) treatment on the inhibition of OSCC growth in vitro and the alteration of microRNA (miRNA) expression profile by the treatment. Materials and Methods: 1,25(OH)2D3-associated apoptosis, cell cycle arrest, and proliferative effect in cultured OSCC cells were assessed using flow cytometry and western blotting methods. miRNA expression profiles were measured using nanoString Sprint Profiller and the Nanostring human miRNA panel. More miRNAs functional pathways were retrieved through bioinformatics using Qiagen IPA system. Results: 1,25(OH)2D3 was found to inhibit the growth of human JHU-22 OSCC cells in a dose-dependent manner with IC50 of 1.56 x 10-6 M. High levels of apoptotic cells and related biomarkers were obtained when the cells were treated with 1,25(OH)2D3. Over 20 miRNAs were upregulated and 23 downregulated by more than two folds, in 1,25(OH)2D3 treated versus untreated JHU-22 cells. Bioinformatics analysis showed molecular functions of most dysregulated miRNAs. For example, MiR-125b-5p upregulated caspases number 2, 6, 7 in addition to upregulating apoptosis facilitator like BCL-2, BIM, and AIF. Conclusion: Our data suggested that 1,25(OH)2D3 function as a OSCC inhibiter is through regulating miRNA expression profile and miRNA function directly or indirectly. 1,25(OH)2D3 has potential to be an anticancer agent for OSCC prevention and treatment. Fold change of top ten unregulated and down regulated miRNAs at nine hour treatment.miRNAControl (C9)Vitamin D (D9)C9/D9hsa-miR-624-3p8283.5hsa-miR-52110272.7hsa-miR-221-5p11292.64hsa-miR-1301-3p7182.57hsa-miR-520a-3p8202.5hsa-miR-153-3p12282.33hsa-miR-122-5p16372.31hsa-miR-120615342.27hsa-miR-125b-5p68615472.26hsa-miR-450b-3p492.25hsa-miR-613219-2.33hsa-miR-147b2611-2.36hsa-miR-525-3p125-2.40hsa-miR-5196-3p+hsa-miR-6732-3p187-2.57hsa-miR-181b-5p+hsa-miR-181d-5p218-2.63hsa-miR-182-3p3212-2.67hsa-miR-941228-2.75hsa-miR-671-3p176-2.83hsa-miR-944186-3.00hsa-miR-1245b-3p246-4.00 Citation Format: Heba Said Ismail Hussein, Wei Wang, Liang Shan, Karl Thompson, Kareem Washington, Gihane Madkour, Xinbin Gu. 1,25-Dihydroxyvitamin D3 inhibits oral squamous cell carcinoma cell growth via microRNA regulation [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4323.
器官移植受者中的角质形成细胞癌
Authors: S. Menzies, E. O'Leary, G. Callaghan, M. Galligan, S. Deady, B. Gadallah, P. Lenane, A. Lally, D.D. Houlihan, P.G. Morris, D.J. Sexton, P.A. McCormick, J.J. Egan, J.P. O'Neill, P.J. Conlon, F.J. Moloney
Journal: British Journal of Dermatology (2019)

接受实体器官移植的人(心脏、肺、肝脏和肾脏)通常会患上皮肤癌。移植患者可能会患上多种皮肤癌,其中一些可能会迅速发展。皮肤癌中最常见的类型是基底细胞癌(BCC)和鳞状细胞癌(SCC)。免疫抑制药物用于防止移植器官排斥。这改变了人体免疫系统,反过来又意味着移植患者更容易患上可迅速生长的皮肤癌。在过去20年中,已经引入了新的免疫抑制剂,它们被认为可以降低皮肤癌的风险。既往研究表明,使用新药可降低 SCC 风险,但迄今为止,尚无研究关注 BCC 的发病率。这项来自爱尔兰的研究旨在发现在过去 20 年中(期间有较新的免疫抑制药物上市),移植患者皮肤癌的发病率是否有所降低。爱尔兰国家癌症登记处登记爱尔兰共和国的所有皮肤癌。作者研究了接受实体器官移植的患者中皮肤癌的发病率,并将其与普通人群中皮肤癌的发病率进行了比较。他们发现,在过去二十年中,接受器官移植的患者中 SCC 和 BCC 的发病率已显著降低。皮肤癌风险的这种变化与免疫抑制剂的变化以及针对移植受者的重点教育和常规皮肤癌筛查相吻合。
StatBite SEER Incidence of Brain and Other Nervous System Cancers 1992-2007
Journal: JNCI Journal of the National Cancer Institute (2010)

The incidence of cancers of the nervous system, including brain cancers like glioblastoma and meningioma, has decreased slightly during the period that cell phones have become common (see news story, p. 928).The downward trend, from about 6.8 new cases per 100,000 people in 1992 to 6.2 per 100,000 in 2007, was statistically significant according to the website of the Surveillance, Epidemiology and End Results (SEER) program of the National Cancer Institute.
Acquired chondronecrosis.
Authors: L Sokoloff
Journal: Annals of the Rheumatic Diseases (1990)

Zonal necrosis of chondrocytes is a characteristic feature of Kashin-Beck disease. Inferences about chondronecrosis in several spontaneous and experimental arthropathies of other species may be relevant to the cause of Kashin-Beck disease and conceivably, too, banal osteoarthritis in man.
The Physiologic Basis of High-Altitude Diseases
Authors: Buddha Basnyat
Journal: Annals of Internal Medicine (2005)

Letters5 April 2005The Physiologic Basis of High-Altitude DiseasesBuddha Basnyat, MDBuddha Basnyat, MDFrom Nepal International Clinic, Kathmandu, Nepal.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-142-7-200504050-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:I read West's review on the physiologic basis of high-altitude diseases (1) with interest. A large recent trial in the Nepalese Himalayas involving 614 western trekkers convincingly showed that Ginkgo biloba was not effective in the prevention of acute mountain sickness (2). Perhaps this study should have been included in West's review. Although this field study did have some limitations, it revealed that gingko caused significantly increased headache when combined with acetazolamide compared with acetazolamide alone.Buddha Basnyat, MDNepal International Clinic; Kathmandu, NepalReferences1. West JB. The physiologic basis of high-altitude diseases. Ann Intern Med. 2004;141:789-800. [PMID: 15545679] LinkGoogle Scholar2. Gertsch JH, Basnyat B, Johnson EW, Onopa J, Holck PS. Randomised, double blind, placebo controlled comparison of ginkgo biloba and acetazolamide for prevention of acute mountain sickness among Himalayan trekkers: the prevention of high altitude illness trial (PHAIT). BMJ. 2004;328:797. [PMID: 15070635] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Buddha Basnyat, MDAffiliations: From Nepal International Clinic, Kathmandu, Nepal. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe Physiologic Basis of High-Altitude Diseases John B. West The Physiologic Basis of High-Altitude Diseases Anil Pandit The Physiologic Basis of High-Altitude Diseases Matiram Pun The Physiologic Basis of High-Altitude Diseases John B. West Metrics Cited byMice lacking 1,4,5-triphosphate inositol type III receptor demonstrate inhibition of hypoxic pulmonary hypertensionEffects of sleep insufficiency on spatial working memory in low-pressure and hypoxic environmentsMinocycline ameliorates hypoxia-induced blood–brain barrier damage by inhibition of HIF-1α through SIRT-3/PHD-2 degradation pathwayMetabolomic analysis of the plasma of patients with high-altitude pulmonary edema (HAPE) using 1H NMR 5 April 2005Volume 142, Issue 7Page: 591KeywordsAltitude sicknessHeadaches ePublished: 5 April 2005 Issue Published: 5 April 2005 Copyright & PermissionsCopyright © 2005 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
SOLUTION OF NITRATE OF SILVER.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transactions of the Maine Medical Association.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ventricles
Authors: Thomas Mampalam
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction: In vivo and in vitro sodium pump activity in subjects with thyrotoxic periodic paralysis
Journal: BMJ (1992)

80-3.7 (41) 11.7 (1.3)* 15.2(16.1)* 172(17.3)* parenteral iron supplementation (2 ml iron dextran 80-3.7 (4.1) 11.7 (10.3)* 15.2 (16.1)* 172 (17.3)* (Imferon, Fisons Pharmaceuticals, Loughborough) 0 weekly for four weeks).In all cases the percentage hypochromia subsequently fell to within the normal o-0 range after six to 14 weeks, with a corresponding increase in the haemoglobin concentration.
Heat-Related Illnesses and Deaths—United States, 1994-1995
Journal: JAMA (1995)

Although heat-related illness and death are readily preventable, exposure to extreme temperatures causes at least 240 deaths during years with no heat wave. A heat wave is defined by the National Weather Service as > or = 3 consecutive days of temperatures > or = 90.0 F (> or = 32.2 C). In 1980, 1983, and 1988 (recent years with prolonged heat waves), 1700, 556, and 454 deaths, respectively, were attributed to heat. This report describes four instances of heat-related illness and death that occurred in the United States during 1994 and 1995 and summarizes risk factors for heat-related illness and death.
RESPIRATORY CHANGES IN AIRPLANE FLIGHTS
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sarcoidosis
Authors: O. J Dempsey, E. W Paterson, K. M Kerr, A. R Denison
Journal: BMJ (2009)

<h3>ABSTRACT</h3> <h3>Background:</h3> Africaid Zvandiri, in partnership with the Ministry of Health and Child Care (MOHCC) in Zimbabwe, implemented a comprehensive, peer-led program, focused on children, adolescents, and young adults living with HIV aged 0–24 years. The peers, known as community adolescent treatment supporters (CATS), are people living with HIV (PLHIV) aged 18–24 years who are trained and mentored to support their peers throughout the HIV care continuum through support groups, home visits, phone call reminders, and messages. We report the HIV care continuum outcomes (HIV testing uptake, antiretroviral therapy [ART] uptake, retention, and viral suppression) in a cohort of household contacts and sexual partners (aged younger than 25 years) of index children, adolescents, and young adults living with HIV identified by CATS from October 2017 to September 2018 in 24 districts of Zimbabwe. <h3>Methods:</h3> This was a retrospective cohort study involving analysis of routine program data, extracted from electronic databases consisting of data on contacts of index PLHIV and ART outcomes. We used April 30, 2019, as the censor date for all analyses. <h3>Results:</h3> A total of 15,223 household contacts and sexual partners with unknown HIV status (linked to 9,353 index PLHIV) were identified and referred for HIV testing. Of these, 12,114 (79.6%) were tested and 1,193 (9.8%) were HIV-positive. Of the latter, 1,153 (96.6%) were initiated on ART with 99% starting on the day of diagnosis. Of those on ART, 1,151 (99.8%) were alive on ART at 6 months and 2 (0.2%) died. A total of 1,044 (91%) children, adolescents, and young people living with HIV underwent viral load testing at 6 months or later, of whom 1,037 (99.3%) were virally suppressed (&lt;1000 copies/ml). <h3>Conclusion:</h3> These findings add to the global evidence demonstrating the effectiveness of peer-led interventions in children, adolescents, and young adults living with HIV and justify the decision of the MOHCC in Zimbabwe to scale-up the model nationally. Future research should aim to understand the reasons for the gaps in HIV testing and viral load testing using qualitative research.