tbuckley/cabot-search huggingface dataset:
PA03: Understanding phenotypic variations of pseudohypoparathyroidism and loss‐of‐function <i>GNAS</i> variants
Authors: N.-Y Kang, J Harrington, P Kannu, E Pope, I Lara-Corrales
Journal: British Journal of Dermatology (2021)

prominent diamond groups, respectively.Individual FLG variants were not associated with specific palmar patterns.Our findings show that LOF variants are associated with eczema severity and skin hydration/epidermal moisture and not TEWL.LOF variants do not account for all the plasticity in phenotype, although they were strongly associated with a prominent diamond pattern.Improved sequencing methods and bioinformatic tools may further improve our ability to find variants, but other mechanisms may affect filaggrin expression in those with the wildtype and in those with LOF variants.
Severe Combined Immunodeficiency Mice Engrafted With Human T Cells, B Cells, and Myeloid Cells After Transplantation With Human Fetal Bone Marrow or Liver Cells and Implanted With Human Fetal Thymus: A Model for Studying Human Gene Therapy
Authors: Sergey Yurasov, Tobias R. Kollmann, Ana Kim, Christina A. Raker, Moshe Hachamovitch, Flossie Wong-Staal, Harris Goldstein
Journal: Blood (1997)
Software
Authors: Alan H. Bennett
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
2A: H. pylori infection leading to cancer
Authors: E Bayerdorffer, A Morgner, A Neubauer, B Rudolph, C Thiede, N Lehn, E Seifert, M Frevel, A Sommer, H Schulz, H Heidt, B Geiter, P Rohde, H Klann, M Stolte, E Bayerdbrffer
Journal: Gut (1996)

MALT lymphoma group Background: Primary gastric low-grade lymphoma of the mucosa asso- ciated lymphoid tissue type has been suggested to arise from chronic H. pylori gastritis.These lymphomas may regress completely in about 70%, when H. pylori infection is cured.We report on a 2 year median follow-up period of 50 patients with MALT lymphoma after cure of H. pylori infection.Methods: 50 patients with consecutive primary gastric MALT lymphoma and H. pylori infection were treated with omeprazole 40 mg tid and amox- icillin 750 mg tid for 14 days to cure the infection.In addition to histology, PCR was used to study proliferation of monoclonal B-cells.Results: 50 patients became H. pylori negative, 2 after a second treatment course.80% (40 out of 50) showed complete histological remission of their lymphoma after a median time period of 5.5 months, and 3 out of 50(6%) so far showed partial remission.6 patients (12%) did not respond to cure of H. pylori infection, and underwent surgical treatment.Of those 6 treated surgically, 4 were found to have a high-grade lymphoma, and 1 patient was found to have a high-grade T-cell lymphoma.1 patient (2%) was primarily treated by chemotherapy (CHOP).PCR showed complete regression of monoclonal bands in most cases.During a median follow-up time period of 24 months, only one relapse of gastric B-cell MALT lymphoma was observed in one patient after 13 months of successful treatment.However, 1 patient developed a high-grade B-cell lymphoma of the nasal concha.Conclusion: These data suggest, that low-grade B-cell MALT lymphoma may regress in more than 70% after cure of H. pyloni infection.Further, remission is stable for at least 2 years in most patients.
Puzzle
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Immunochemical Analysis of Bronchogenic Carcinomatous Sputum With Special Reference to Secretion-Specific Protein
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum to: Extensive next-generation sequencing analysis in chronic lymphocytic leukemia at diagnosis: clinical and biological correlations
Authors: Gian Matteo Rigolin, Elena Saccenti, Cristian Bassi, Laura Lupini, Francesca Maria Quaglia, Maurizio Cavallari, Sara Martinelli, Luca Formigaro, Enrico Lista, Maria Antonella Bardi, Eleonora Volta, Elisa Tammiso, Aurora Melandri, Antonio Urso, Francesco Cavazzini, Massimo Negrini, Antonio Cuneo
Journal: Journal of Hematology & Oncology (2016)
Drug Perception and the Student-Teacher Gap
Authors: Stanley H. Schuman
Journal: JAMA (1971)

A field test of a university-produced innovative film for teenagers which emphasizes motivations of drug behavior rather than drug facts produced some surprising results. Standard methods of film showing and collecting written individual responses were used in nine secondary schools in southeast Michigan. Among 500 viewers— 428 students and 72 faculty—a consistent and striking perception gap was noted: drug clues were correctly identified by 32.9% of the students compared to only 12.5% of the teachers and counselors (<i>P</i>= &lt;.001). Girls scored somewhat higher than boys, but there was remarkably little variation between schools by urbanization or economic scale. Such a gap in drug awareness has serious implications for those who would teach, counsel, or treat teenagers today.
Error in Author Name
Authors: Arsh Patel, Mohammad Jafferany
Journal: JAMA Dermatology (2020)

Within dermatology, interest in mental health can understandably vary; however, the notable overlap should not be ignored.The distinct patient characteristics of DoP and its increasing prevalence call for the further involvement of dermatologists and multidisciplinary teams when appropriate.Proper patient identification, mindful engagement, and initiation of treatments with referrals when needed are essential for improving disease-related outcomes.Specific characteristics of patients with DoP provide the clarity and increased understanding needed to improve disease-related outcomes.For example, demographic information can assist in the identifying and confirming a diagnosis for affected individuals.In a study including 115 patients with the condition, Pearson et al 2 report that most of the included patients were middle-aged (median age, 52 years), female (77%), and White (77%).Our findings closely mimic the aforementioned results, with a significantly higher mean age (56 years) and greater female predominance (221 [74%]) found in patients with DoP (n = 299) compared with the general population of individuals with psychocutaneous diseases. 1 An additional point of consideration when treating patients with DoP involves gathering proper patient history.In particular, health care clinicians should take a thorough record of any previous mental health diagnoses and screen for possible misuse of prescription medication or use of illicit drugs.In a study including 92 patients at a university psychodermatology clinic, Zhu et al 3 reported that patients with DoP were significantly more likely to have narcotic and stimulant medication prescriptions.Illicit drug use is also a concern, as Pearson et al 2 reported that more than 50% of included patients indicated a history of drug use or exposure to solvents.Frequently, individuals suspected to have the condition are reluctant to seek treatment from mental health professionals and are observed to be defensive when this treatment is abruptly recommended. 4As such, patient consultations are suggested to be performed within a neutral space without use of possibly triggering labels like psychodermatology, delusional, or psychotic.Additionally, although potentially time consuming, treating physicians are urged to engage in meaningful dialogue to build trust.In particular, the focus of the conversation should be placed on symptom management without questioning the nature of the delusional thinking. 4ealth care clinicians are in a unique position to not only identify patients with psychocutaneous conditions like Morgellons disease, but also play a role in the treatment process to ultimately improve their overall quality of life.
Long-term Cardiovascular Consequences of Diuretics vs Calcium Channel Blockers vs Angiotensin-Converting Enzyme Inhibitors--Reply
Authors: J. T. Wright
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tort Claims and Federal Regulation of Medical Devices vs Pharmaceuticals—Reply
Authors: Lawrence O. Gostin
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE OCULAR MANIFESTATIONS OF INTRACRANIAL TUMOR.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Computers
Authors: H. Paul Johnson
Journal: JAMA (1964)

<h3>To the Editor:—</h3> If the use of computers in processing medical data falls heir to the same errors as it has in commercial fields it will, in some instances, be far from an unmixed blessing. Around the first of the year a large concern with whom I have occasion to do business converted to computers. Inadvertently, my name became listed under two different code numbers, and each month I received two bills. In spite of continuous correspondence, not only about the two bills but also concerning numerous errors in items, it took them until today to find the errors and enclose a check for overpayment of my account. Even now I am not sure that all the errors have been corrected. Computers are merely speed mechanisms. They are no better than the individuals who feed the data.
Abstract P051: Heterogeneity in the Association of Low Birth Weight with Adult-onset Diabetes: The Brazilian Longitudinal Study of Adult Health
Authors: Noel T Mueller, James Yarmolinsky, Bruce B Duncan, Dora Chor, Isabela M Bensenor, Rosane H Griep, Sandhi M Barreto, Maria Ines Schmidt
Journal: Circulation (2016)

Background: Low birth weight is related to adult-onset diabetes, although this association has been sparsely investigated in developing countries. Given reports of sexual dimorphism in fetal programming, we aimed to investigate heterogeneity, by sex and maternal diabetes, in the association of low birth weight with type 2 diabetes in participants from a large Brazilian cohort. Methods: We used baseline (2008-2010) data of 12,066 participants aged 35-74y from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Diabetes was defined by self-reported information and laboratory measurements (OGTT or HbA 1c ). We employed multivariable-adjusted Poisson regression models with robust variance to estimate prevalence ratios (PR) and 95% confidence intervals (CI). Results: Nine hundred and ninety participants (~8% of the total) reported low birth weight (defined as &lt;2.5 kg). Low birth weight was associated with higher prevalence of diabetes in a fully-adjusted model in women (PR 1.54, 95% CI: 1.32-1.80 vs. birth weight of 2.5-4kg), but not in men (PR 1.09, 95% CI 0.91-1.29; P heterogeneity &lt;0.01). Additionally, the association was stronger among participants who had mothers with diabetes (PR 1.60, 95% CI 1.33-1.93), than those who did not (PR 1.18, 95% CI 1.01-1.38; P heterogeneity &lt;0.05). When jointly stratified by sex and maternal diabetes, the low birth weight-diabetes association was observed for women with (PR 1.67, 95% CI 1.28-2.19) and without (PR 1.50, 95% CI 1.25-1.81) maternal diabetes. In contrast, in men, low birth weight was associated with diabetes in participants with maternal diabetes (PR 1.51, 95% CI 1.17-1.93), but not in those without (PR 0.93, 95% CI 0.74-1.18). High birth weight was marginally and homogenously associated with lower prevalence of diabetes. Conclusions: Low birth weight was variably associated with higher prevalence of diabetes in Brazilian adults. The heterogeneity observed supports complex and sex-specific intra-uterine environmental effects on adult metabolic health.
Plasma theophylline concentrations, six minute walking distances, and breathlessness in patients with chronic airflow obstruction
Authors: W V Evans
Journal: BMJ (1985)

Twenty patients with chronic bronchitis were given incremental dosages of a new slow release preparation of theophylline and observed for its effect on lung function and exercise tolerance.Measurements were made subjectively by using visual analogue scales and objectively using six minute walking distances and spirometry.The study was placebo controlled and had a double blind randomised design.In the dosages used (200, 400, 600, and 800 mg) theo- phylline produced no significant improvement in forced expiratory volume in one second or forced vital capacity, and there was no overall improvement in peak expiratory flow rate.Similarly, neither effort tolerance nor degree of breathlessness appeared to be influenced by the drug, even when unacceptably high dosages were used.By contrast, placebo yielded a 7% increase in the six minute walking distance.From these results it seems difficult to justify the routine, indiscriminate use of theophylline for chronic bronchitis.
Ablation of mitral myocardial muscle effect on annular and leaflet dynamics in the context of mitral repair Tomasz A. Timek, David T. Lai, David Liang, Gerald Berry, Frederick A. Tibayan, Paul Dagum, George T. Daughters, Neil B. Ingels, Jr., D C. Miller. Stanford University, Stanford, CA, Research Institute of the Palo Alto Medical Foundation, Palo Alto, CA
Journal: Journal of the American College of Cardiology (2001)
Diet termination for PKU: Yes or no?
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review Simplified Diabetic Manual, with 163 International Recipes (American, Jewish, French, German, Italian, Armenian and so forth) . By Abraham Rudy, M.D. Introduction by Frederick M. Allen, M.D. 8°, 216 pp., with tables, charts and illustrations. New York: M. Barrows and Company, Incorporated, 1940. $2.00.
Journal: New England Journal of Medicine (1941)
Common Skin Diseases.
Journal: JAMA (1933)

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Trichotillomania: Etiology and Treatment
Journal: JAMA (1988)

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