tbuckley/cabot-search huggingface dataset:
Assessing prior history of sexually transmitted disease
Authors: M. T. McHugh
Journal: JAMA (1992)

<h3>To the Editor.</h3> —The letter by Fleisher et al<sup>1</sup>raises significant questions regarding the reliability of identifying women at risk for acquiring human immunodeficiency virus (HIV) infection by assessing prior history of sexually transmitted disease (STD). Their work clearly shows how women at high risk for STD do not know what infections constitute STD and may incorrectly answer the global question: "Have you ever had an STD?" As physicians treating adolescents who are also high risk for acquiring STD and HIV, it is our experience that even fewer than the 25.8% cited by Fleisher et al may indeed know that they have been found to have and been treated for STD. This is especially true for those infected with chlamydia, trichomonas, and venereal warts (human papillomavirus). Given the importance and difficulty in obtaining a good general medical history for adolescents, it is likely that there is often less information
Retraction
Journal: Annals of the Rheumatic Diseases (2016)

Great concerns rose about the following points: 1. Aggregation of age data at the age of 60 years constituting 26.4% of the placebo group and 22.2% of the Methotrexate group despite that data is ranging between 60 to 78 years and 60 to 84 years in both groups respectively.2. Correlation between age of the disease is evident among only the Methotrexate group (r=0.323,P=0.006) while no correlation between both variables in the placebo group (r=0.131,P=0.275).3. Coding system of the comorbidity variable is not clearif it is either scale variable or categorical variablewhich raises concerns about validity of the method of analysis used.4. Analysis of comorbidity (using data sent by the authors) revealed different results than that published ( page 7 in output attachment).5. Baseline VAS was nearly perfectly correlated in the placebo group with its 2nd reading at 28 weeks (r=0.927,P<0.0001), while that correlation doesn't not even exist among the Methotrexate group (r=0.023,P=0.859).6. "VAS mean difference" used in the paper was calculated using the mean percent difference which was not clear or mentioned in the research published.7. Errors were made in the analysis of "VAS mean difference" by including the missing values (given the code 99) in the analysis resulting in an evident errors (Page 12 output attachment).8. Analysis of the scores used yielding different results than that published."The Investigation Committee's report concluded: "There is an unintentional mistake in the statistical process, with errors in collection of data in some groups".In the course of discussions with ARD about the paper, over a number of months, the authors provided three different data sets and proposed corrections to the text and two of the tables in the paper.ARD considered that the corrections to the paper were significant and was not able to agree to them for that reason and because of unresolved concerns about the reliability of the data in the paper and in the corrections.
Rheumatology
Authors: Daniel J. McCarty
Journal: JAMA (1984)

... interferons, interleukins, arachidonic acid metabolites, and cell-derived chemotactic factors. New knowledge about rheumatic diseases has been generated at an ever-increasing pace. Comparison of the first edition of<i>Arthritis and Allied Conditions</i>, edited by Bernard Comroe (1940), with the subsequent nine editions provides ample documentation. A few recent highlights are discussed herein. Perhaps the most striking recent discovery is the spirochetal etiology of Lyme arthritis, now more properly termed "Lyme disease."1 This syndrome was first detected in Lyme, Conn, because of a close geographic clustering of children with what was thought to be juvenile rheumatoid arthritis. The illness begins in warm weather as a characteristic rash, consisting of an expanding reddened area with central clearing and induration called "erythema chronica migrans." This lesion (stage 1) is sometimes followed weeks to months later by cardiac or neurological symptoms (stage 2) and weeks to years later by arthritis (stage 3). Lyme disease is
ACUTE INFECTIOUS MULTIPLE NEURITIS.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The National Football Head and Neck Injury Registry. Report and conclusions 1978
Authors: J. S. Torg
Journal: JAMA (1979)

The National Football Head and Neck Injury Registry has documented 1,129 injuries since 1971 that involved hospitalization for more than 72 hours, surgical intervention, fracture-dislocation, permanent paralysis, or death. Of this group of injuries, 550 were fracture-dislocations of the cervical spine, of which 176 were associated with permanent quadriplegia. It appears that during the last two decades, there has been a decrease in the incidence of direct fatalities, head injuries associated with intracranial hemorrhage, and injuries associated with death. Conversely, cervical spine injuries with fracture-dislocation and with permanent quadriplegia have increased. We believe that these observations are the result of the development of a protective helmet-face mask system that has effectively protected the head, and by so doing has allowed it to be used as a battering ram in tackling and blocking techniques, thus placing the cervical spine at risk of injury. (<i>JAMA</i>241:1477-1479, 1979)
The Bill for the Re-organization of the Personnel of the Navy.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Editorial Board
Authors: Leann Starken, Rochester Minn, John Boston, Gerald Gleich, Charles Kirkpatrick Bethesda, E Stiehm, Los Angeles, Monroe Stamford, Richard Madison, Joiin Ohman Boston, Hal Richerson, Iowa City, Ross Rocklin Boston, Raymond Slavin, St Louis, Robert Stroud Dullas, Harvey Colten Boston, Fred Kantor, New Haven, Robert Schwartz Rochester, John Yunginger
Journal: Journal of Allergy and Clinical Immunology (1979)
CORONARY OCCLUSION: A THROMBOTIC DISORDER?
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Presented antigen from damaged pancreatic β cells activates autoreactive T cells in virus-mediated autoimmune diabetes
Authors: Marc S. Horwitz, Alex Ilic, Cody Fine, Enrique Rodriguez, Nora Sarvetnick
Journal: Journal of Clinical Investigation (2002)

The induction of autoimmunity by viruses has been attributed to numerous mechanisms. In mice, coxsackievirus B4 (CB4) induces insulin-dependent diabetes mellitus (IDDM) resembling the final step of disease progression in humans. The immune response following the viral insult clearly precipitates IDDM. However, the molecular pathway between viral infection and the subsequent activation of T cells specific for islet antigen has not been elucidated. These T cells could become activated through exposure to sequestered antigens released by damaged β cells, or they could have responded to factors secreted by the inflammatory response itself. To distinguish between these possibilities, we treated mice harboring a diabetogenic T cell repertoire with either the islet-damaging agent streptozotocin (STZ) or poly I:C, which nonspecifically activates T cells. Significantly, only treatment of mice with STZ resulted in IDDM and mimicked the effects observed following CB4 infection. Furthermore, antigen-presenting cells from STZ-treated mice were shown to directly activate autoreactive T cells and induce diabetes. Therefore, the primary role of CB4 in the precipitation of IDDM is to damage tissue, causing release and presentation of sequestered islet antigen. These events stimulate autoreactive T cells and thereby initiate disease.
ELEMENT OF CONSENT IN SURGICAL OPERATIONS.
Journal: JAMA (1890)

Apropos of a recent editorial in the<i>Medical Record</i>on "The Responsibility of the Physician for Experiments upon Patients, even with the latters' Consent," we are reminded of the exhaustive discussion upon " The Medico-Legal Relations of Abdominal Surgery " held in the Section on Jurisprudence at the last meeting of the American Medical Association. In that discussion, the necessity of obtaining the consent of the patient and friends, before proceeding to open the abdomen, was especially insisted upon by several speakers, and from this the discussion branched to the element of consent generally in surgical operations. The view most readily accepted in that meeting was that more than simple consent was required in surgical operations— while that was essential; the operation itself must be in the line of approved surgical procedure. A case was quoted in which a young man had his testicles removed because of amorous proclivities. He subsequently
Correction
Journal: BMJ (1964)

Any Questions ?NBWT 1383Loewenthal' ' has made claims that the antihistamine triprolidine will protect against both normal and pathological skin responses to sunlight.But his evidence appears to be based on uncontrolled observation.Gordon,'Vitzpatrick et al., ' and Lloyd and Johnson,' in carefully controlled work, have failed to confirm Loewenthal.It is unfortunate and also regrettable that the earlier claims have recently received some publicity,' because they encourage the public in the self-treatment of abnormal photosensitivity without medical surveillance.This was referred to in Drug and Thera- peutics Bulletin.
Ventricular Fibrillation
Authors: Namrata Gumaste
Journal: JAMA Cardiology (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Cardiology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Cardiology journal
The Patent Laws and Patent Office Practice
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Quality of Life for Long-Term Survivors of End-Stage Renal Disease
Authors: Elva O. Poznanski, Emily Miller, Carlos Salguero, Robert C. Kelsh
Journal: JAMA (1978)

Eighteen children and adolescents who survived two years or longer in an attempt to manage their end-stage renal failure by transplantation were studied. The psychological adaptation of the young person to this form of management of renal disease was assessed by a semistructured interview of the patient and his parents. Fifty percent of the patients functioned at school or on the job and did not have depression. The remaining half did less well. In our institution a satisfactory quality of life required a successful transplant. (<i>JAMA</i>239:2343-2347, 1978)
New stool immunoassay offers routine diagnostic tool for H pylori infection
Journal: BMJ (1999)

Sweetness and sucking have analgesic effect in babiesTreating pain in the newborn is essential for ethical reasons and because pain can lead to decreased oxygenation, haemodynamic instability, or increased intracranial pressure.Simple interventions such as sweet oral solutions or sucking a pacifier can reduce pain in neonates during painful minor procedures.On p 1393 Carbajal et al report the results of a comparison of the analgesic effects of these two simple interventions during venepuncture in neonates by using a behavioural pain scale.They found that the non-nutritive sucking of a pacifier was more effective than the oral administration of 30% glucose or 30% sucrose.A 30% glucose solution, which is readily available in any hospital, showed at least the same analgesic effect as a 30% sucrose solution.A synergistic analgesic effect was observed for sucrose and pacifiers.These simple and safe interventions should be widely used for minor procedures in neonates.
Adverse reactions to antiarrhythmic drugs during therapy for ventricular arrhythmias
Authors: T. W. Nygaard
Journal: JAMA (1986)

We analyzed the incidence of adverse reactions to antiarrhythmic drugs in 123 consecutive patients with a history of sustained ventricular tachycardia or ventricular fibrillation. Blood levels were measured serially and were maintained within the usual therapeutic range. Minor reactions were defined as those that required dosage reduction and major reactions as those that required drug discontinuation or permanent pacing for bradycardia. A total of 237 individual, oral drug trials were evaluated in the 123 patients. Adverse reactions were noted in 79 trials (33%) Fifty-nine (48%) of the 123 patients had one or more adverse reaction. Major reactions were noted in 36 patients (29%). Adverse effects occurred during 49% of trials with mexiletine hydrochloride, 44% of trials with amiodarone, 24% of trials with procainamide hydrochloride, and 18% of trials with quinidine sulfate or gluconate. In conclusion, clinically significant adverse reactions are common during drug therapy for ventricular arrhythmias. These observations indicate that with the drugs used in this study, an acceptable risk-benefit ratio will be possible only in patients at a significant risk for a symptomatic arrhythmia. Antiarrhythmic drug therapy in patients at low risk for serious arrhythmia should be discouraged. (<i>JAMA</i>1986;256:55-57)
Cutaneous Surgery
Authors: Larry E. Millikan
Journal: JAMA (1995)

The last two decades have seen explosive growth in the practice of dermatologic surgery, which has played an increasing role in the routine practice of dermatology. Textbooks meeting a corresponding need included Epstein and Epstein's<i>Techniques in Skin Surgery</i>(now through the fourth edition), Bennett's<i>Fundamentals of Cutaneous Surgery</i>(1988), and Roenigk and Roenigk's<i>Dermatologic Surgery</i>(1989). Dr Wheeland has edited the newest text, which features an impressive list of contributors. As with any multiauthor text, there is variability from chapter to chapter, from average to excellent. The division of the book into five parts is a rational one, allowing grouping of appropriate topics, with the first, "Basic Surgical Concepts and Procedures," providing an excellent overview of and introduction to dermatologic surgery. A comprehensive approach to basic concepts is very useful, in my estimation, for teaching residents. The chapters of the first part, beginning with history and followed shortly by
Pre-B Cell Receptor Signaling Prevents Leukemic Transformation by BCR-ABL1.
Authors: Daniel Trageser, Lars Klemm, Sebastian Herzog, Yong-mi Kim, Cihangir Duy, Wolf-Karsten Hofmann, John Groffen, Nora Heisterkamp, Hassan Jumaa, Markus Muschen
Journal: Blood (2007)
Reply
Authors: H.C. Williams, H. Forsdyke, G. Boodoo, R.J. Hay, P.G.J. Burney
Journal: British Journal of Dermatology (1996)

Journal Article Reply Get access H.C. Williams, H.C. Williams Department of Dermatology, Queen's Medical Centre, University Hospital, Nottingham NG7 2UH, U.K. Search for other works by this author on: Oxford Academic Google Scholar H. Forsdyke, H. Forsdyke Department of Dermatology, Queen's Medical Centre, University Hospital, Nottingham NG7 2UH, U.K. Search for other works by this author on: Oxford Academic Google Scholar G. Boodoo, G. Boodoo Department of Dermatology, Queen's Medical Centre, University Hospital, Nottingham NG7 2UH, U.K. Search for other works by this author on: Oxford Academic Google Scholar R.J. Hay, R.J. Hay Department of Dermatology, Queen's Medical Centre, University Hospital, Nottingham NG7 2UH, U.K. Search for other works by this author on: Oxford Academic Google Scholar P.G.J. Burney P.G.J. Burney Department of Dermatology, Queen's Medical Centre, University Hospital, Nottingham NG7 2UH, U.K. Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 135, Issue 5, 1 November 1996, Pages 857–858, https://doi.org/10.1111/j.1365-2133.1996.tb03906.x Published: 01 November 1996
Campaign of Vaccination.
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Report of Symposium: Viruses, arthritis, and connective tissue disorders
Journal: Annals of the Rheumatic Diseases (1974)

Viruses, arthritis, and connective tissue disorders* A one-day Symposium on the putative role of virus infections in connective tissue diseases was organized by the Arthritis and Rheumatism Council and held at The Royal College of Physicians, London, on Friday, March 22, 1974.The speakers considered the strategy of virus infection, the various forms of host response, and the ways in which these can be altered.The immunopathological features of chronic virus infections were also reviewed.Examples of arthritis known to be induced by viruses were described and, finally, the evidence for virus infection in connective tissue diseases of unknown aetiology was discussed.arthritis and the joint involvement has a variable relation