tbuckley/cabot-search huggingface dataset:
Assessment of Coronary Heart Disease Morbidity and Mortality After Radiation Therapy for Early Breast Cancer
Authors: K. A. Vallis
Journal: Journal of Clinical Oncology (2002)

PURPOSE: To assess the risk of fatal and nonfatal myocardial infarction (MI) after breast-conserving surgery (BCS) and radiation therapy (RT) for left-sided breast cancer. PATIENTS AND METHODS: A hospital-based retrospective cohort linkage study of all breast cancer patients registered at the Princess Margaret Hospital (PMH), Toronto, Canada, between 1982 and 1988 who were treated with postlumpectomy RT was performed. Available identifiers for the study cohort were linked to two province-wide health files: the Canadian Institute for Health Information Hospitalization File and the Ontario Mortality Database. Admissions to hospital for MI and deaths attributable to MI were identified. The relevant original health records were abstracted to verify the diagnosis of MI according to diagnostic criteria used in the World Health Organization multinational monitoring of trends and determinants in cardiovascular disease (MONICA) project. We compared incidence of MI in the study cohort with the general population and incidence of MI after therapy for left- versus right-sided breast cancer. RESULTS: A cohort of 2,128 patients was identified. The median length of follow-up was 10.2 years. The incidence of MI in the study cohort was comparable to that in an age-matched general population of women in Ontario. There were 70 coronary events among 56 patients after breast irradiation. According to MONICA criteria, 53 and six events were characterized as definite and possible MIs, respectively. Eleven events did not satisfy MONICA criteria for MI. Twenty-six patients treated for left-sided and 23 patients treated for right-sided breast cancer experienced at least one definite or possible MI (log-rank test, P = .66). There were eight fatal MIs among the left-sided group and six among the right-sided group. There was no excess of other cardiac diseases among patients who received left-sided radiotherapy compared to the right-sided group. CONCLUSION: We have found no evidence for excess morbidity and mortality from coronary artery disease among women treated with RT to the left breast after BCS at 10.2 years of follow-up. Longer follow-up is required to confirm that excess cardiac disease has been completely avoided.
Abstracts
Journal: Annals of the Rheumatic Diseases (1964)

This paper is a detailed report of two patients with advanced nodular rheumatoid arthritis, not treated with corticosteroid hormones, who died suddenly with a clinical diagnosis of cerebrovascular disease.Radio- graphs of the cervical vertebrae had not been obtained.In both cases the medulla oblongata was compressed by the odontoid process following severe atlanto-axial subluxation.
Bad Breath
Authors: Alan R. Hirsch
Journal: JAMA (1988)

<h3>To the Editor. —</h3> I would like to comment on the fine article on phantosmia by Dr Bailey<sup>1</sup>in the May 27 issue of<i>JAMA</i>. I believe that another likely cause for phantosmia in the patient described would be the olfactory reference syndrome. Pryse-Phillips<sup>2</sup>first characterized olfactory hallucinations in psychiatric diseases. Olfactory hallucinations can be divided into two classes—those that seem to emanate from an external source and those from the individual himself. In both types, the hallucinated odor is foul. The first type is perceived as the odor of chemicals or of other people or animals. It doesn't fatigue and can continue for months at a time. (The perception of smell is rarely continuous in patients with structural or organic brain disease, whereas in purely psychological diseases it is almost always continuous.) The second type is intrinsic—the odor seems to come from the patient himself, ie, the
Zinc deficiency in cirrhosis predicts hepatic decompensation and mortality
Authors: Marta Hernández Conde, Elba Llop, Beatriz Tormo, Christie Perelló, Marta López-Gómez, Javier Abad Guerra, Luis Rodríguez, José Luis Martínez Porras, Natalia Fernández Puga, Maria Trapero, Carlos Ferre, Enrique Fraga, José Luis Calleja Panero
Journal: Journal of Hepatology (2020)
Vinorelbine and low dose cyclophosphamide in pediatric sarcoma. A pilot study for the future European rhabdomyosarcoma protocol
Authors: M. Casanova, A. Ferrari, G. Bisogno, J. H. Merks, G. L. De Salvo, K. Tettoni, M. Provenzi, F. Fossati Bellani, M. Carli
Journal: Journal of Clinical Oncology (2004)

8540 Background: Following our previous report (Casanova et al. Cancer 2002; 94: 3263) on the activity of vinorelbine (VNB) in rhabdomyosarcoma (RMS), we report the results of a pilot study aimed to define the dose of VNB in combination with low dose continuous oral cyclophosphamide (CTX) in patients with refractory or recurrent sarcomas. The study was performed in the view of utilizing this treatment as maintenance therapy in the future European protocol for high risk RMS patients. Methods: The dose of CTX was fixed at 25 mg/m2/day for 28 days. VNB given i.v. on days 1, 8, and 15 was escalated from a starting dose of 15 mg/m2 by 5-mg/m2 increments in subsequent cohorts of at least 3 patients until the maximum tolerated dose was reached. Results: Between April 2003 and November 2003, 18 patients (10 M, 8 F) aged 2–23 years (median 12) received 88 cycles (9 had RMS). There was a median of 2 prior regimens (range 1–4); 5 patients previously received high dose chemotherapy with PBSC rescue and 12 prior radiotherapy. Three patients were treated at dose level 1, 4 at dose level 2, and 3 at dose level 3. Among 5 patients treated at dose level 4 (VNB 30 mg/m2) 2 dose limiting toxicities (grade 4 neutropenia) were observed in the first 2 cycles therefore a decision was made to enter 3 more patients at dose level 3. In the 39 cycles administered at dose level 3, neutropenia grade ≥ 3 was observed in 14 (36%) with no other major toxicity. The interval between courses 1 and 2 was as scheduled (28 days) in 12 patients, 5 had a delay ≤ 3 days. One patient, with parameningeal RMS who underwent RT a few weeks before study entry, had a delay of 2 weeks due to prolonged grade 2 mucositis. A median of 5 cycles (range 1–10) were administered per patient. Four patients were still on treatment after 5–10 cycles. Partial responses were observed in 7/17 assessable patients: 3/8 RMS (2 embryonal, 1 alveolar), 1/1 clear cell sarcoma, 1/2 synovial sarcoma, 1/2 desmoplastic small round cell tumor, 1/1 osteosarcoma. Conclusions: This combination appears to be feasible and active in relapsed sarcoma. Recommended doses for the new study will be CTX 25 mg/m2/day for 28 days and VNB 25 mg/m2 on days 1,8, and 15. No significant financial relationships to disclose.
Norwalk-Like Viral Gastroenteritis in US Army Trainees—Texas, 1998
Journal: JAMA (1999)

During August 27-September 1, 1998, 99 (12%) of 835 soldiers in one unit at a U.S. Army training center in El Paso, Texas, were hospitalized for acute gastroenteritis (AGE). Their symptoms included acute onset of vomiting, abdominal pain, diarrhea, and fever. Review of medical center admission records for AGE during the previous year indicated that fewer than five cases occurred each month. This report describes the outbreak investigation initiated on August 30 by a U.S. Army Epidemiologic Consultation Service (EPICON) team; the findings indicated the outbreak was caused by a Norwalk-like virus (NLV).
On Authorship
Authors: Franklin G. Miller
Journal: The American Journal of Bioethics (2011)

"On Authorship." The American Journal of Bioethics, 11(10), pp. 32–33 Acknowledgments This article is not subject to U.S. Copyright Law. The opinions expressed are those of the author and do not reflect the position or policy of the National Institutes of Health, the Public Health Service, or the Department of Health and Human Services.
Development and Progression of Diabetic Retinopathy in Adolescents and Young Adults With Type 2 Diabetes: Results From the TODAY Study
Authors: Jeanie B. Tryggestad, Megan M. Kelsey, Kimberly L. Drews, Steven D. Chernausek, Elia N. Escaname, Elvira Isganaitis, Sarah Macleish, Siripoom McKay, Jennifer Sprague, Steve Willi
Journal: Diabetes Care (2021)

The Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) study reported a 13.9% prevalence of diabetic retinopathy (DR) in youth with mean ± SD type 2 diabetes duration of 4.9 ± 1.5 years. After 7 years of additional follow-up, we report the risk factors for progression of DR in the TODAY cohort.
Hemoglobin Binding of Aromatic Amines: Molecular Dosimetry and Quantitative Structure. Activity Relationships for N-Oxidation
Authors: Gabriele Sabbioni
Journal: Environmental Health Perspectives (1993)

Aromatic amines are important intermediates in industrial manufacturing.N-Oxidation to N-hydroxyarylamines is a key step in determining the genotoxic properties ofaromatic amines.N-Hydroxyarylamines can form adducts with DNA, with tissue proteins, and with the blood proteins albumin and hemoglobin in a dose-dependent manner.The determina- tion of hemoglobin adducts is a useful tool for biomonitoring exposed populations.We have established the hemoglobin binding index (HBI) [(mmole compound/mole hemoglobin)/(mmole compound/kg body weight)] ofseveral aromatic amines in female Wistar rats.Including the values from other researchers obtained in the same rat strain, the logarithm of hemoglobin binding (logHBI) was plotted against the following parameters: the sum of the Hammett constants (Ea = up + am), pKa, logP (octanol/water), the half-wave oxidation potential (EIA), and the electronic descriptors of the amines and their corresponding nitrenium ions obtained by semin-empirical calculations (MNDQ AM1, and PM3), such as atomic charge densities, energies ofthe highest occupied molecular orbit and lowest occupied molecular orbit and their coeffi- cients, the bond order of C-N, the dipole moments, and the reaction enthalpy [MNDOHF, AM1HF or PM3HF = Hf(nitrenium) -Hf(amine)J.The correlation coefficients were determined from the plots of all parameters against log HBI for all amines by means of linear regression analysis.The amines were classified in three groups: group 1, all para- substituted amines (maximum, n = 9); group 2, all amines with halogens (maximum, n = U); and group 3, all amines with alkyl groups (maximum, n = 13).For the amines of group 1, logHBI correlates with Ea, AMIH, EA, the pKa, and the logPwith r = 0.84,073,0.72, -0.69and 0.50, respectively.For the amines ofgroup 2, logHBI correlates with pKa, Eua, MNDOHF, E%A, and logP with r = 0.81, -0.0, -0.55, -0A6, and -0.20, respectively.For the amines of group 3, logHBI correlates with with E,½, PM3HF, Es, pKa, and logP with r = 0.92,089, 0.75, 0.19 and 0.12, respectively.This investiga- tion shows for a large variety ofaromatic amines the bioavailability of N-hydraKyarylamine (the genotoxic metabolite) and the utility of electronic descriptors for prediction of N-oxidation.
Corrigenda
Journal: British Journal of Dermatology (2008)

British Journal of DermatologyVolume 158, Issue 3 p. 657-657 Free Access Corrigenda This article corrects the following: Ichthyosiform erythroderma with rickets: report of five cases G. Sethuraman, B.K. Khaitan, S.S. Dash, K. Chandramohan, V.K. Sharma, M. Kabra, K.K. Verma, R. Goswami, S. Thulkar, Volume 158Issue 3British Journal of Dermatology pages: 603-606 First Published online: December 7, 2007 First published: 11 February 2008 https://doi.org/10.1111/j.1365-2133.2008.08445.xAboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Ichthyosiform erythroderma with rickets: report of five cases. Br J Dermatol 2008, Sethuraman et al. The above mentioned article1 contained an error in reference number 3. The first author was listed as ‘Devidayal Dayal D’. The name should in fact have appeared as ‘Dayal D’. The Journal apologises for this error. References 1 Sethuraman G, Khaitan BK, Dash SS, Chandramohan K, Sharma VK, Kabra M, Verma KK, Goswami R, Thulkar S. Ichthyosiform erythroderma with rickets: report of five cases. Br J Dermatol 2008; 158: 604– 7. Web of Science®Google Scholar Volume158, Issue3March 2008Pages 657-657 ReferencesRelatedInformation
Die Spezifizität der serologischen Reaktionen
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Indirect Blood Pressure Recording in Helicopters
Authors: William Hollis
Journal: JAMA (1973)

<h3>To the Editor.—</h3> The use of helicopters in the civilian community is markedly increasing. One of their most vital tasks is the handling of injured or acutely ill individuals. The use of helicopters in the Republic of South Vietnam to rapidly move people from the field of battle to primary medical facilities has decreased combat mortality and morbidity significantly. In the United States, the use of the helicopter in the handling of automobile accidents, other types of industrial accidents or injuries, and the rapid transfer of injured or ill patients from one hospital facility to another has found an increasing demand. One problem facing physicians and allied medical personnel involved in the use of helicopters today is the monitoring of a patient's vital signs while in flight. The high noise and vibration levels of most helicopters make the usual indirect recording of blood pressure impossible. The following study was undertaken
Costs, charges, conscience, and control (lost)
Authors: G. D. Lundberg
Journal: JAMA (1983)

Have you seen the most recent report on the rate of inflation overall and by its several components?<sup>1</sup> The Consumer Price Index rose at an annualized rate of 4.1% during August 1983. By comparable calculations, physician services rose by only 3.4%, but medical care rose by 8.0%. This increase was produced primarily by the hospital room component, which climbed at an annualized rate of 17.8%. Good grief!! Can't we do better than that? This 17.8% figure doesn't even include many other hospital budget elements wherein creative hospital directors and accountants have traditionally "laid it off on the ancillaries." Is the hospital industry (wherein physicians certainly influence costs) intentionally riding "hell bent for leather" toward destruction of self-control or is this simply ignorance? From many years of working with large bureaucratic budgets, I am tempted to lay part of the blame for this extraordinary spurt on what was the then-impending
BOOK REVIEW
Authors: J. D. RIZZO
Journal: JNCI Journal of the National Cancer Institute (1995)

Journal Article BOOK REVIEW Get access Handbook of Supportive Care in Cancer Jean Klastersky , Stephen C. Schimpff , Hans-JÖrg Senn , eds. New York : Marcel Dekker , Inc., 1995 , 616 pp. illus. $99.75. ISBN 0-8247-9276-6 J. DOUGLAS RIZZO, M.D J. DOUGLAS RIZZO, M.D 600 N. Wolfe St., Rm. 126 Baltimore, MD 21287 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 87, Issue 17, 6 September 1995, Page 1328, https://doi.org/10.1093/jnci/87.17.1328 Published: 06 September 1995
Membership of educational committees (as of July 1, 1983)
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
OBSERVATIONS SUGGESTED BY "SYPHILITIC SCARS OF THE SPIRIT"
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
FIVE CASES OF GLIOMA OF THE RETINA IN ONE FAMILY
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE ENCYCLOPEDIA BRITANNICA AND THE DATE OF THE INTRODUCTION OF ANESTHESIA
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Clarification of Conflict of Interest Disclosure in: Studying Complementary and Alternative Therapies
Authors: Sarah Sheridan, Robert Ware, Keith Grimwood, Stephen Lambert
Journal: JAMA (2012)

vaccine with very good to excellent effectiveness. 4 Our findings suggest the most important factor, in this cohort, may be the initial vaccine received.It is unlikely our findings during the current outbreak are the result of detection bias because this would require health care-seeking behavior, or the likelihood of laboratory testing or reporting, to be associated with the primary course received by children over a decade previously.Possible explanations for our findings could include antigenic shifts in circulating Bordetella pertussis strains 2 or the different immune responses from acellular and whole-cell priming. 5The lesser protection provided by DTaP, both as the initial vaccine or full primary course, may be due to linked epitope suppression, when the initial exposure locks in the immune response to certain epitopes and inhibits response to other linked epitopes on subsequent exposures. 6 The challenge for future pertussis vaccine development is to address the benefit-risk trade-off highlighted by our study, and to develop vaccines that induce long-lasting protection from the first dose, without the adverse events associated with DTwP use.