tbuckley/cabot-search huggingface dataset:
LODGE PRACTICE AND THE WELL-TO-DO.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Renewed control efforts emphasize 'unrecognized' influenza threat
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Hyperthyroid Crisis
Authors: Stephen R. Newmark
Journal: JAMA (1974)

THYROTOXIC storm is an overwhelming or uncompensated form of thyrotoxicosis.<sup>1</sup>Thyrotoxic storm appears commonly in two settings: After surgery, when the thyrotoxic patient has been prepared inadequately or the diagnosis of hyperthyroidism was not recognized preoperatively. In this instance, either "surgical stress" or direct manipulation of the gland results in acute release of thyroid hormone into the peripheral blood. More commonly, thyrotoxic storm arises during an intercurrent "stressful" medical illness, such as uncontrolled diabetes or ketoacidosis, trauma, or infection. Clinical manifestations are those of severe hypermetabolism. Fever is always present and ranges from 38 C (100 F) to 41 C (106 F). The skin has a fine texture and is warm and flushed. Sweating may be profuse. Pulse is rapid and atrial fibrillation may be present. Although the blood pressure is well maintained initially, shock may result ultimately. Pulmonary edema may be present, particularly if there is underlying cardiac
Canadian Medical Association Journal, Toronto
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Crizotinib in ROS1 rearranged or MET deregulated Non-Small-Cell Lung Cancer (NSCLC): Preliminary results of the METROS trial
Authors: L. Landi, R. Chiari, A. Delmonte, A. Morabito, S. Tamberi, F. Barbieri, R. Buosi, C. Gridelli, M. Tiseo, V. Gebbia, G. Fontanini, L. Crinò, F. Cappuzzo
Journal: Annals of Oncology (2016)
Histological diagnosis of chronic hepatitis B and C . Divisione Medica FBF Hospital, Erba, *Divisione Crespi Niguarda Hospital Milan, Italy
Journal: Hepatology (1995)

Les malades en situation de précarité dans les poches le pauvreté existantes dans les pays riches cumulent des facteurs de précarité : chômage de longue durée, absence de logement fixe, absence de protection sociale effective, solitude. Ceux-ci constituent autant de facteurs de vulnérabilité aux pathologies infectieuses, première cause de morbidité et de mortalité dans ce contexte. Résurgence de maladies infectieuses anciennes (tuberculose mais aussi rickettsioses, diphtérie ou pneumococcies) curables si correctement traitées; émergence de pathologies récentes (VIH, VHB, VHC) nécessitent des soins et des traitements longs et coûteux; leur survenue chez des personnes en situation de précarité impose une prise en charge adaptée. La détection doit être systématique, la prévention spécifique, l'hospitalisation supplantée par le suivi ambulatoire; la prise en charge nécessite le développement des dispositifs médico-sociaux de proximité au sein des hôpitaux publics et des dispensaires municipaux. L'accès aux soins des plus vulnérables est la condition d'une diminution de la mortalité des pathologies infectieuses et du contrôle des épidémies émergentes ou résurgentes qui se d'eveloppent dans les poches de pauvreté et sont un risque pour tous.The destitute from the poorest socio-economic classes of industrialized countries accumulate many exclusion factors: long-term unemployment, absence of stable housing, absence of effective health and social coverage, isolation, low income. All of these factors render them vulnerable to infectious diseases, the leading cause of morbidity and mortality in this context. Re-emergence of well-known epidemics (tuberculosis, but also ricketsiosis, diphteria, and pneumococcal diseases) which are curable if correctly treated, and the emergence of new epidemics (HIV, HVB, HVC) requiring long and costly treatments, make it necessary to develop health and social car settings adapted to these populations. Detection must be systematic, prevention specific, ambulatory care must replace hospitalization when possible, the care and the follow-up of these populations require that both medical social services in public hospitals and neighborhood dispensaries be set up. Access to care for the most vulnerable is imperative if mortality of infectious diseases is to be decreased and to control both new and re-emerging epidemics which develop in these pockets of poverty but also dangerous for the whole population.
Drug-Induced Deafness
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
We Hate to See You Go, A.D.K.
Authors: E.J. H
Journal: Annals of Internal Medicine (1972)

Editorial Notes1 March 1972We Hate to See You Go, A.D.K.E.J. HE.J. HSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-76-3-507 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptAficionados of the essay now have one less practitioner of the art to follow. The 18 December 1971 issue of the Canadian Medical Association Journal brings the unpleasant news that A.D.K. has closed his column, Aequanimitas, in that journal.A.D.K.'s column brought us his views of diverse scenes and matters and the reflections they induced—the early work on insulin as seen by him when a medical student, the pleasures of a lunch counter in Toronto, the gaplessness of the generation gap. Surely most of the readers of theCMAJcame to know that A.D.K.'s column was the first page to... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 March 1972Volume 76, Issue 3Page: 507-507KeywordsInsulin ePublished: 1 December 2008 Issue Published: 1 March 1972 PDF downloadLoading ...
Personal View
Authors: A. Paton
Journal: BMJ (1969)

<h3>Abstract</h3> Analysis and interpretation of neuroimaging datasets has become a multidisciplinary endeavor, relying not only on statistical methods, but increasingly on associations with respect to other brain-derived features such as gene expression, histological data, and functional as well as cognitive architectures. Here, we introduce BrainStat - a toolbox for <i>(i)</i> univariate and multivariate linear models in volumetric and surface-based brain imaging datasets, and <i>(ii)</i> multidomain feature association of results with respect to spatial maps of <i>post-mortem</i> gene expression and histology, task-based fMRI meta-analysis, as well as resting-state fMRI motifs across several common surface templates. The combination of statistics and feature associations into a turnkey toolbox streamlines analytical processes and accelerates cross-modal research. The toolbox is implemented in both Python and MATLAB, two widely used programming languages in the neuroimaging and neuroinformatics communities. BrainStat is openly available and complemented by an expandable documentation.
Operative arthroscopy
Authors: Jan Gillquist
Journal: Endoscopy (1980)

Today operative arthroscopy has become increasingly accepted as the method of choice for many knee disorders. Extraction of loose or foreign bodies, division of the medial plica, shaving the patella or fixation of osteochondritis are examples of procedures suitable for the arthroscope. However, arthroscopy has had the largest impact on therapeutic principles in the field of meniscus surgery. It is now technically possible to operate all meniscus lesions endoscopically. The technique developed in Linköping, Sweden, involves the use of a special knife. The principles for removal of flap tears, bucket handles and for subtotal meniscectomy is described. Selection of type of operation can be done according to the need of the particular patient with this technique. The equipment is fairly inexpensive and no operating arthroscopy is needed. The results in the first 200 cases were good or excellent in the majority of patients. The off-work period is very short.
THE CONUNDRUM OF CARDIOMYOPATHIES
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
NECROLOGY
Journal: JAMA (1883)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 1823: SNORD78 promotes prostate cancer progression and regulates AR expression and signaling
Authors: Alan P. Lombard, Chengfei Liu, Cameron M. Armstrong, Leandro S. D'Abronzo, Wei Lou, Christopher P. Evans, Allen C. Gao
Journal: Cancer Research (2019)

Abstract While small nucleolar RNAs (snoRNAs) have long been thought of as housekeeping genes, emerging evidence now suggests that snoRNAs are involved in more than previously thought and also in the development of disease. In cancer, it is understood that snoRNA expression and function can be altered, but little is known regarding the role of snoRNAs in these diseases. SNORD78 is a C/D box snoRNA which has been shown to be overexpressed in prostate cancer and associated with disease progression. However, there are no studies functionally characterizing SNORD78 in prostate cancer. In this study we sought to understand the functional contribution of SNORD78 in prostate cancer progression. Oncomine was used to assess SNORD78 expression in clinical prostate cancer samples. LNCaP and C4-2B prostate cancer cell lines were used. We used siRNAs to inhibit SNORD78 expression and cell viability assays to assess cell growth. ELISAs were used to assess PSA secretion and cell death. Western blots and quantitative PCR were used to assess cell death (PARP-cleavage) and AR expression and signaling. We found that SNORD78 expression was up-regulated in prostate tumors and associated with metastatic progression. Cell viability assays demonstrated that inhibition of SNORD78 expression resulted in a drastic reduction in prostate cancer cell growth and lower secretion of PSA into the media. Cell death ELISAs and western blots for cleaved-PARP showed that SNORD78 inhibition induced robust apoptosis in both LNCaP and C4-2B cells. As the androgen receptor (AR) is the primary target for prostate cancer therapy, we tested whether SNORD78 regulated AR expression and signaling. Inhibition of SNORD78 in both LNCaP and C4-2B cells resulted in reduced AR mRNA and protein levels. We also found that SNORD78 knockdown led to decreased levels of PSA and NKX3.1, suggesting that AR downstream signaling was inhibited. Our findings suggest that SNORD78 promotes prostate cancer cell viability and disease progression. We also demonstrate that SNORD78 regulates the AR and may be involved in promoting AR signaling needed for prostate cancer cell survival. Collectively, these data suggest that SNORD78 plays a critical role in prostate cancer progression and may represent a novel therapeutic target. Citation Format: Alan P. Lombard, Chengfei Liu, Cameron M. Armstrong, Leandro S. D'Abronzo, Wei Lou, Christopher P. Evans, Allen C. Gao. SNORD78 promotes prostate cancer progression and regulates AR expression and signaling [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1823.
DRUG–ELUTING STENTS FOR THE TREATMENT OF LEFT MAIN CORONARY ARTERY DISEASE WITH BIFURCATED LESIONS: A COMPARISON WITH SIROLIMUS, PACLITAXEL, ZOTAROLIMUS (ENDEAVOR RESOLUTE), BIOLIMUSA9, EPC CAPTURE AND EVEROLIMUS–ELUTING STENT: MULTICENTER REGISTRY IN ASIA
Authors: Sunao Nakamura, Hisao Ogawa, Hans Yeo, Wasan Udayachalerm, Damras Tresukosol, Sudaratana Tansuphaswadikul
Journal: Journal of the American College of Cardiology (2013)
Premiership doctor
Authors: Seema Haider, Nicholas Ramscar
Journal: BMJ (2006)

How exactly do you get into sports medicine and what does it involve? <b>Seema Haider</b> and <b>Nicholas Ramscar</b> spoke to <b>Ian Beasley</b> of Arsenal Football Club, the other north London football club, and here9s what he had to say
High Concentrations of Heavy Metals in Neighborhoods near Ore Smelters in Northern Mexico
Authors: Andrea L. Benin, James D. Sargent, Madeline Dalton, Sandy Roda
Journal: Environmental Health Perspectives (1999)

In developing countries, rapid industrialization without environmental controls has resulted in heavy metal contamination of communities. We hypothesized that residential neighborhoods located near ore industries in three northern Mexican cities would be heavily polluted with multiple contaminants (arsenic, cadmium, and lead) and that these sites would be point sources for the heavy metals. To evaluate these hypotheses, we obtained samples of roadside surface dust from residential neighborhoods within 2 m of metal smelters [Torreón (n = 19)] and Chihuahua (n = 19)] and a metal refinery [Monterrey (n = 23)]. Heavy metal concentrations in dust were mapped with respect to distance from the industrial sites. Correlation between dust metal concentration and distance was estimated with least-squares regression using log-transformed data. Median dust arsenic, cadmium, and lead concentrations were 32, 10, and 277 microg/g, respectively, in Chihuahua; 42, 2, and 467 microg/g, respectively, in Monterrey, and 113, 112, and 2,448 microg/g, respectively, in Torreón. Dust concentrations of all heavy metals were significantly higher around the active smelter in Torreón, where more than 90% of samples exceeded Superfund cleanup goals. At all sites, dust concentrations were inversely related to distance from the industrial source, implicating these industries as the likely source of the contamination. We concluded that residential neighborhoods around metal smelting and refining sites in these three cities are contaminated by heavy metals at concentrations likely to pose a health threat to people living nearby. Evaluations of human exposure near these sites should be conducted. Because multiple heavy metal pollutants may exist near smelter sites, researchers should avoid attributing toxicity to one heavy metal unless others have been measured and shown not to coexist.
Life History Traits Impact the Nuclear Rate of Substitution but Not the Mitochondrial Rate in Isopods
Authors: Nathanaëlle Saclier, Clémentine François, Lara Konecny-Dupré, Nicolas Lartillot, Laurent Guéguen, L. Duret, Florian Malard, Christophe Jean Douady, Tristan Lefébure
Journal: Molecular Biology and Evolution (2019)
THE BRITISH ASSOCIATION OF DERMATOLOGY AND SYPHILOLOCIY
Journal: British Journal of Dermatology (1930)

British Journal of DermatologyVolume 42, Issue 10 p. 450-451 THE BRITISH ASSOCIATION OF DERMATOLOGY AND SYPHILOLOCIY First published: October 1930 https://doi.org/10.1111/j.1365-2133.1930.tb09372.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Volume42, Issue10October 1930Pages 450-451 RelatedInformation
The increased plasma levels of C-reactive protein following oral hormone replacement therapy are not related to an increased inflammatory response Giuseppe M. C. Rosano, Otavio Gebara, Massimo Fini, Jos� Aldrighi, Filipo Leonardo, Mauricio Wajngarten, Jos� A. F. Ramires. San Raffaele Hospital - Roma - Tosinvest Sanit�, Roma, Italy, University of Sao Paulo, Sao Paulo, Brazil
Journal: Journal of the American College of Cardiology (2001)