tbuckley/cabot-search huggingface dataset:
DANGER OF SMALLPOX HOSPITALS.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Nathan Smith Davis. An autobiographical letter, previously unpublished
Authors: W. J. Bell
Journal: JAMA (1973)

Nathan Smith Davis (1817-1904), physician, teacher, author, and editor, was one of the most influential and powerful figures in the American medical profession for more than half a century. He inaugurated the movement that led to the founding of the American Medical Association, served as the Association's president in 1864, and was the first editor of its<i>Journal</i>. Not inappropriately, he has been called "the father of the American Medical Association." In 1875, in response to a query from Dr. Joseph M. Toner of Washington (himself a president of the Association and an indefatigable collector of biographical lore), Dr. Davis wrote a long autobiographical letter, valuable for its account of his early years and as interesting for what it omits as for what it relates of his later career. The letter, not previously published, is preserved in volume 73 of the Toner Papers in the Library of Congress; in the
Evaluation of a Hypocholesterolemic Agent
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ECDC adds new pages to online directory on infection prevention and control
Authors: Collective Eurosurveillance editorial team
Journal: Eurosurveillance (2015)

Preview this article: ECDC adds new pages to online directory on infection prevention and control, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/20/18/art21119-en-1.gif
Varicella-zoster virus vaccine
Authors: P. A. Brunell
Journal: JAMA (1978)

<h3>To the Editor.—</h3> In his discussion of the new Japanese chickenpox vaccine (238:1731, 1977), Albert B. Sabin, MD, provides a somewhat superficial analysis of the morbidity produced by varicella. The implication that the chickenpox vaccine may reduce the morbidity owing to zoster or the statement that the use of the vaccine will not produce more zoster than natural infections, moreover, are entirely speculative. Although chickenpox is a very contagious disease that is contracted by almost all children, it is usually quite mild. Most of the morbidity tends to be concentrated in a relatively small group of immunocompromised persons and in adults. Immunocompromised persons are easily identified, and in most the illness can be modified by passive immunization. The total deaths owing to chickenpox encephalitis were 14, 10, and 12 during the last three years (reports are available). Of major concern is the fact that varicella-zoster virus, as the name implies,
Medical Meanings: A Glossary of Word Origins
Authors: J. H. Dirckx
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contact dermatitis from spandex brassieres
Authors: H. L. Joseph
Journal: JAMA (1967)

Nine patients had allergic contact dermatitis to elastic materials in brassieres and one had the same reaction to a girdle. Three had classical rubber dermatitis, but the remainder were sensitive to spandex, a stretchable, synthetic fabric. Some of these patients also were contact sensitive to mercaptobenzothiazole (MBZ). Their spandex sensitivity presumably relates in most instances to the MBZ trace contamination of spandex in certain but not all brands. The patients could wear spandex brands that appeared to be uncontaminated with MBZ.
Abstract 3604: Synthetic lethality therapy for lung cancers with compromised glutathione homeostasis
Authors: Xiang Yan, Bingliang Fang
Journal: Cancer Research (2019)

Abstract Glutathione (GSH)/GSH reductase (GSR) and thioredoxin/thioredoxin reductase (TXNRD) are two major compensating thiol-dependent antioxidant pathways that maintain protein dithiol/disulfide balance. We hypothesized that functional deficiency in one of these systems will render cells dependent on compensation by the other system for survival, providing a mechanism-based synthetic lethality approach for treatment of cancers. The human GSR gene is located on chromosome 8p12, a region frequently lost in human cancers. GSR deletion was detected in about 6% of lung adenocarcinomas in The Cancer Genome Atlas database. To test whether loss of GSR sensitizes cancer cells to TXNRD inhibition, we knocked out or knocked down the GSR gene in human lung cancer cells and evaluated their response to the TXNRD inhibitor auranofin. The results showed that GSR deficiency sensitized lung cancer cells to this agent. A correlation analysis of auranofin sensitivity and gene expression levels in a panel of 129 NSCLC cell lines revealed that auranofin sensitivity correlated with the expression levels of the GSR, glutamate-cysteine ligase catalytic subunit (GCLC), and NAD(P)H quinone dehydrogenase 1 (NQO1) genes. In NSCLC patient-derived xenografts with reduced expression of GSR and/or GCLC, growth was significantly suppressed by treatment with auranofin. Together, these results provide proof-of-concept evidence that cancers with compromised expression of enzymes required for GSH homeostasis or with chromosome 8p deletions that include the GSR gene may be targeted by a synthetic lethality strategy with TXNRD inhibitors. Citation Format: Xiang Yan, Bingliang Fang. Synthetic lethality therapy for lung cancers with compromised glutathione homeostasis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 3604.
Tetanus Prophylaxis
Authors: Gerhart A. Drucker
Journal: JAMA (1961)

<h3>To the Editor:—</h3> In their article on "Tetanus Prophylaxis" inThe Journal, Sept. 3, 1960, Filler and Ellerbeck recommend that physicians no longer use tetanus antitoxin in patients not previously immunized against tetanus, who have suffered "trivial" wounds. If the wound is more extensive, they recommend the use of antibiotics in addition to local treatment. They would reserve tetanus antitoxin for massive or extensive wounds seen late in non-immunized persons. They state that in trivial wounds, if proper local treatment is given, the danger of tetanus is very small, while the danger of complications from tetanus antitoxin is between 10 and 15%. I cannot agree with these recommendations. Medical students have been taught for years that it is just the small, trivial wound, such as a rusty nail puncture wound, a deep wooden splinter, or a powder burn, in which there is great danger of tetanus. The epidemics of tetanus
The Efficacy of Novel CFTR Inhibitors on the Secretory Function of Rat Colonic Mucosa
Authors: A Patel, DL Bovell, AD Corbett, RJ Holdsworth
Journal: Endoscopy (2006)

Aims: To examine the efficacy of the novel Cystic Fibrosis Transmembrane Regulator (CFTR) inhibitors CFTR inh-172 and GlyH-101 on secretory responses to carbachol in rat colonic mucosa.
Amount of nicotine and carbon monoxide inhaled by smokers of low-tar, low-nicotine cigarettes
Authors: R. V. Ebert
Journal: JAMA (1983)

In 76 smokers, correlations between plasma nicotine and alveolar carbon monoxide levels of the individual smoker and the nicotine and CO yields of his cigarette were very poor. In 24 smokers of low-nicotine, low-tar cigarettes, mean alveolar CO levels did not differ from those of smokers of regular cigarettes. Mean plasma nicotine levels were lower in smokers of low-nicotine cigarettes, but a wide overlap of individual values occurred. The implication that an individual shifting to ultra-low-tar cigarettes reduces risks of cardiopulmonary disease is unwarranted. (<i>JAMA</i>1983;250:2840-2842)
Injuries Among Construction Workers During the Raising of Wood-Framed Walls— Colorado and California
Journal: JAMA (1995)

In Colorado, traumatic spinal cord injuries that produce documentable motor, sensory, bowel, and/or bladder impairments must be reported to the state or local health department. Persons with such injuries are interviewed by staff of the Colorado Department of Public Health and Environment (CDPHE) Spinal Cord Injury Early Notification System (ENS)*; injuries that occur in workplaces are investigated by staff of the CDPHE Sentinel Event Notification System for Occupational Risk (SENSOR) program. This report describes the investigation of a construction-related spinal cord injury reported to the CDPHE SENSOR program on February 8, 1993, and summarizes information about a similar case in California.(ABSTRACT TRUNCATED AT 250 WORDS)
Teratologic Evaluation of Ethylene Glycol Monobutyl Ether in Fischer 344 Rats and New Zealand White Rabbits Following Inhalation Exposure
Authors: Rochelle W. Tyl, Guillermo Millicovsky, Darol E. Dodd, Irvin M. Pritts, Kathryn A. France, Louan C. Fisher
Journal: Environmental Health Perspectives (1984)

Timed-pregnant Fischer 344 rats and New Zealand White rabbits were exposed to ethylene glycol monobutyl ether vapors by inhalation on gestational days 6 through 15 (rats) or 6 through 18 (rabbits) at concentrations of 0, 25, 50, 100 or 200 ppm. The animals were sacrificed on gestational day 21 (rats) or 29 (rabbits). In rats, exposure to 200 or 100 ppm resulted in maternal toxicity (clinical signs, decreased body weight and weight gain, decreased absolute and relative organ weights, decreased food and water consumption and evidence of anemia), embryotoxicity (increased number of totally resorbed litters and decreased number of viable implantations per litter) and fetotoxicity (reductions in skeletal ossification). No increase in fetal malformations was observed in any exposure group relative to controls. At 50 or 25 ppm, there was no maternal, embryo or fetal toxicity (including malformations) in rats. In rabbits, exposure to 200 ppm resulted in maternal toxicity (apparent exposure-related increases in deaths and abortions, clinical signs, decreased weight during exposure and reduced gravid uterine weight at sacrifice) and embryotoxicity (reduced number of total and viable implantations per litter). No treatment-related fetotoxicity was seen. No treatment-related increased in fetal malformations or variations were seen at any exposure concentration tested. There was no evidence of maternal, embryo, or fetal toxicity (including malformations) at 100, 50 or 25 ppm in rabbits.
SOME CURRENT TRENDS IN ENDOCRINOLOGY
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
JAMA Reference Directories
Journal: JAMA (1982)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum: AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not maintenance of hematopoietic stem cells in adult hematopoiesis
Authors: M Ichikawa, T Asai, T Saito, G Yamamoto, S Seo, I Yamazaki, T Yamagata, K Mitani, S Chiba, H Hirai, S Ogawa, M Kurokawa
Journal: Nature Medicine (2005)
GEORGE FREDERICK STILL (1868-1941)
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
High-Dose Oral Vitamin D Supplementation and Risk of Falls in Older Women—Reply
Authors: Kerrie M. Sanders
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Proprietary Prescribing in Great Britain
Journal: JAMA (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Highlights
Journal: JAMA Psychiatry (2018)

Cannabidiol has antipsychotic effects, but its brain actions are not well understood.Bhattacharyya and colleagues conducted a double-blind, placebo-controlled randomized clinical trial and found that clinical high risk (CHR) participants receiving placebo showed reduced right caudate, parahippocampal gyrus, and midbrain activation compared with healthy participants, whereas CHR participants receiving cannabidiol showed partial normalization of these abnormalities.Thus, cannabidiol positively affects brain circuitry critical to the emergence of psychosis in the CHR state. Residential Mobility Over the Life Course and Psychosis 1128Residential mobility may be a risk factor for psychosis.Using a cohort of more than 1.4 million people born in Sweden over 14 years, Price and colleagues studied residential mobility and psychosis and found that more frequent moves during childhood and adolescence were associated with greater risk; moving greater distances before age 16 years was also associated with elevated risk of psychosis.This study indicates children and adolescents with less disruption in their residential environments were less likely to experience psychotic disorders in early adulthood.
Animal
Authors: A. Iles
Journal: BMJ (2003)

A play written by Kay Adshead Soho Theatre, London W1, until 27 September For details about performances and future tour dates see http://www.theredroom.org.uk/ Rating: ![Graphic][1]</img>![Graphic][2]</img>![Graphic][3]</img> Animal is a play about anger management. One of its three characters, Pongo, has been living on the streets for 30 years and has volunteered to take part in a trial to test a new drug for anger management and riot control. Dr Lee is an aspiring psychiatrist with designs on the success of the new drug, TR14 (later known as Tranqton). And Elmo is a compassionate psychiatric nurse who has his own problems with anger. The play takes … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif [3]: /embed/inline-graphic-3.gif
Promotion of cigarettes in developing countries
Authors: R. M. Davis
Journal: JAMA (1986)

A recent article<sup>1</sup>and editorial<sup>2</sup>inThe Journalexplored the epidemiology and ethical implications of exporting a hazardous product beyond the borders of the United States. In this case, the product was turtles. Another example of such activity is the marketing and promotion of cigarettes in developing countries by US manufacturers and their foreign subsidiaries. The Surgeon General has called cigarette smoking "the chief, single, avoidable cause of death in our society and the most important public health problem of our time."<sup>3</sup>In addition, cigarette smoking is well on its way to becoming the number one health problem in the Third World.<sup>4</sup> The role of US manufacturers in foreign cigarette consumption may involve the exportation of US-made cigarettes or the exportation of unmanufactured tobacco for cigarette production outside the United States. In 1984, US manufacturers exported 56.5 billion cigarettes and 246,156 tons of unmanufactured tobacco.<sup>5</sup>