tbuckley/cabot-search huggingface dataset:
Hospital Peer Review: A New Proposal
Authors: Arthur Kaufman
Journal: JAMA (1994)

<h3>To the Editor.</h3> —For many years the basis of hospital peer review has been internally driven by physicians and nurses reviewing one another. This has been accomplished by volunteer physicians through hospital committees at no cost to the institution. To our knowledge, the real cost in terms of person-hours has never been calculated, but it has never been a concern because of willing volunteerism. As public confidence in our ability to review ourselves has eroded, the concept of "external" peer review has developed. This has the obvious advantage of reviewers' not being personally involved with the "reviewees," but also has the major disadvantage of cost. We must consider that as physicians' incomes decrease with health system reform and as demands on our time increase, the willingness of physicians to volunteer this service may diminish. At some point, reviewers both internally and externally may demand payment for services rendered. Nevertheless, up
Death rate among 795 patients in first year after myocardial infarction
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Atrial Fibrillation
Authors: Sharon Parmet, Cassio Lynm, Richard M. Glass
Journal: JAMA (2007)

Atrial FibrillationA trial fibrillation (also called AF or A Fib) is the most common form of sustained arrhythmia (heart rhythm disorder).Atrial fibrillation is more common in older people, people with high blood pressure, and people with other kinds of heart disease.It can lead to serious health problems such as stroke, fatigue, and heart failure.The December 19, 2007, issue of JAMA includes an article about treatments for heart arrhythmias.This Patient Page is based on one previously published in the August 27, 2003, issue of JAMA.
Improved cognition after control of risk factors for multi-infarct dementia
Authors: J. S. Meyer
Journal: JAMA (1986)

A cohort of 52 patients (30 men and 22 women) with multi-infarct dementia (MID) has been followed up prospectively for a mean interval of 22.2 months. Clinical course has been documented by serial history taking and interviews and neurological, medical, and psychological examinations, and correlated with measurements of cerebral blood flow. The clinical course and cognitive performance have been compared with those of age-matched normal volunteers and patients with Alzheimer's disease. Patients with MID were subdivided into hypertensive and normotensive groups, and also into those displaying stabilized or improved cognition and those whose condition deteriorated. Among hypertensive patients with MID, improved cognition and clinical course correlated with control of systolic blood pressure within upper limits of normal (135 to 150 mm Hg), but if systolic blood pressure was reduced below this level, patients with MID deteriorated. Among normotensive patients with MID, improved cognition was associated with cessation of smoking cigarettes. (<i>JAMA</i>1986;256:2203-2209)
Trichinosis
Authors: Thomas B. Magath
Journal: JAMA (1961)

<h3>To the Editor:—</h3> The letter to the editor from Drs. Walters and Shelton (<i>JAMA</i>, Dec. 31, 1960, p. 2236) indicates there is a great deal of misunderstanding concerning trichinosis in the United States. They decry the "high incidence of trichinosis still found in our population today." They quote Dammin to the effect that the disease "apparently afflicts 15 to 20 per cent of our population. The mortality has been estimated at about five per cent in symptomatic and diagnosed human cases." They decry the fact that no inspection of hogs is carried out by the Department of Agriculture to condemn infected animals. They observe that the Department quit such inspection a half century ago because there was no known method of detection of these worms in order to effect the removal of all infected hogs. They could have added that the Department did not want to set up in the
Jumping Genes
Authors: P L Cohen
Journal: New England Journal of Medicine (1995)

To the Editor: The study by Perriëns et al. (March 23 issue) 1 demonstrates that extending antituberculous treatment from 6 to 12 months reduces the rate of relapse in patients infected with the human immunodeficiency virus (HIV) who have pulmonary tuberculosis.In spite of this, the authors considered the six-month program to be an acceptable alternative because the longer-term therapy did not prolong survival.We question the validity of their survival analysis and therefore their recommendations for treatment.The short follow-up after treatment (1 year for patients in the 12-month treatment group) along with the unacceptable percentage of patients lost to follow-up (34 percent) lessens the statistical power of the study to reach that conclusion.The authors argue that most relapses could be successfully retreated.As shown in Table 2 of the article, only 20 of 335 patients (6 percent) died of tuberculosis in the first episode, as compared with 3 of 9 patients (33 percent) who relapsed (P ϭ 0.01 by Fisher's exact test).We also doubt that the patients who were lost to follow-up and those who are not enrolled in carefully controlled studies have the same opportunities for diagnosis and treatment as the patients who completed follow-up in the study by Perriëns et al.This point is even more important if patients are treated for only six months, because such patients have a greater risk of relapse.The theoretical savings afforded by a shorter course of thera-py may be counteracted by the need for closer follow-up.Furthermore, close follow-up is not an easy matter in HIV-infected patients, as reflected by the 34 percent rate of loss to follow-up.We believe that treatment of tuberculosis in HIV-infected patients must be continued for at least 9 months 2 as long as subsequent studies confirm that regimens lasting 6 months or 9 to 12 months are associated with the same rates of survival.
ANOTHER DOCTOR IN LITERATURE.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE PROFESSION OF GETTING HURT.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INFLUENZA.
Authors: G. E. CRAWFORD
Journal: JAMA (1900)

I have chosen a somewhat commonplace and hackneyed subject, but it is that which we meet most frequently that is of the most importance to us as physicians. The people have long since ceased to regard influenza as a joke; and the profession is coming to realize that it ranks among the more serious maladies with which we have to deal. The percentage of reported deathrate is small, yet on account of the vast number of cases the aggregate is very large. Besides, a large majority of the deaths directly due to influenza are reported under the names of the so-called complications and sequelæ which are in fact essential parts of the disease. The average death-rate of a community during the prevalence of influenza is always greatly augmented, and frequently doubled. This comes the nearest to the facts in the case, and shows that during certain periods there are as
Dog
Authors: Jack Coulehan
Journal: JAMA (2006)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Trigeminal Neuralgia Relieved by Ophthalmic Anesthetic
Authors: Claus M. Fichte
Journal: JAMA (1991)

<h3>To the Editor. —</h3> Trigeminal neuralgia is an ailment of unknown cause for which treatment is generally far from satisfactory. It was therefore a welcome surprise when one of us (M.R.Z.), having had some four acute episodes of the ailment over a 7-year period, found his symptoms completely relieved after ophthalmologic examination prior to cataract removal. The only action in the preliminary workup that may offer an explanation was the instillation of 2 drops of an eye anesthetic (0.5% proparacaine hydrochloride) into the right eye. Divisions 1 and 2, and occasionally 3, of the trigeminal nerve had been affected on the right side. Both the acute symptoms and the dull ache over the temporal distribution of the nerve, which had existed between the acute exacerbations, disappeared. One minor exacerbation occurred 2 weeks later, and it was treated with 2 drops of the same anesthetic agent. Since the initial apparent effect,
Where are the children of the 'dirty war'? Science seeks answers for their relatives
Authors: C. Raymond
Journal: JAMA (1989)

"HOW LONG does it take for the bones of a 6-month-old child to dissolve?" With a voice periodically quavering with emotion, geneticist Mary-Claire King, PhD, recalled the grisly question posed to her one day in 1984. She replied that bones don't dissolve. "Tears came to his eyes, and he said, 'Then Matilda is still alive,'" King said in a speech in San Francisco at the annual meeting of the American Association for the Advancement of Science (AAAS). The man's question was less a scientific query than an emotional plea. He wanted to know why a grave containing the remains of his daughter, son-in-law, and two of their children lacked any evidence of Matilda but for her pajamas. Nevertheless, science is providing some solace to him and many other bereft grandparents in his troubled nation. King and a team of fellow geneticists and molecular biologists have been helping a group of
Coexistence of sleep apnea and asthma resulting in severe sleep hypoxemia
Authors: D. W. Hudgel
Journal: JAMA (1979)

ALTHOUGH significant hypoxemia may be present during status asthmaticus,<sup>1</sup>severe hypoxemia is unusual in chronic bronchial asthma.<sup>2</sup>We report the case of a patient with chronic bronchial asthma who had mild hypoxemia while awake, but the patient was unusual in that he had erythrocytosis. During sleep he had severe hypoxemia that was primarily due to obstructive apnea. A tracheostomy was required for effective treatment of the apnea and hypoxemia. <h3>Report of a Case</h3> A 66-year-old man from Detroit was referred to National Jewish Hospital and Research Center for evaluation and treatment of asthma. The patient had frequent episodes of intermittent dyspnea accompanied by wheezing for 2 1/2 years before admission. He had never been a cigarette smoker and produced minimal sputum. The patient reported more dyspnea during sleeping hours and awakening almost hourly. His spouse related a history of his loud snoring accompanied by fitful sleep, which had
Effect of Acetylcholine Infusion upon Cardiac Dynamics in Patients with Pulmonary Emphysema
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Depression and anxiety symptoms in bereaved caregivers of patients with advanced cancer.
Authors: Areej El-Jawahri, Joseph Greer, Vicki A. Jackson, Emily R. Gallagher, Mihir Kamdar, Simone Rinaldi, Jennifer S. Temel
Journal: Journal of Clinical Oncology (2019)

17 Background: Caregivers of patients with advanced cancer experience substantial caregiving burden and psychological distress during the illness course. However, data on depression and anxiety symptoms in bereaved caregivers and factors associated with their psychological distress are lacking. Methods: We conducted a secondary analysis of 168 caregivers enrolled in a randomized trial of early palliative care integrated with oncology care versus oncology care alone for patients newly-diagnosed with incurable lung and non-colorectal gastrointestinal cancers and their caregivers who completed bereavement assessments at 3 months after their loved one’s death. We used the Hospital Anxiety and Depression Scale (HADS) to assess patients’ and caregivers’ depression and anxiety symptoms at baseline within 8 weeks of diagnosis, and at 3-4 months after the patient’s death (for caregivers). We asked caregivers to rate patient’s physical and psychological distress in the last week of life on a 10-point scale. We used linear regression adjusting for randomization and cancer type to explore associations between patient and caregiver factors and bereaved caregivers’ depression and anxiety. Results: 30.4% (51/168) and 43.4% (73/168) of bereaved caregivers reported clinically significant depression and anxiety symptoms, respectively. Younger patient age (B = -0.06, P = 0.041), higher patient baseline anxiety (B = 0.28, P = 0.002), and caregiver rating of worse physical (B = 0.28, P = 0.035) and psychological (B = 0.41, P &lt; 0.001) distress experienced by the patient at the end of life (EOL) were associated with worse depression symptoms in bereaved caregivers. Only caregiver factors, including age (B = -0.07, P = 0.004), female sex (B = 1.60, P = 0.024), and rating of worse psychological distress experienced by the patient at the EOL (B = 0.42, P &lt; 0.001) were associated with worse bereaved caregivers’ anxiety symptoms. Conclusions: Bereaved caregivers of patients with advanced cancer experience substantial psychological distress which is associated with their perceptions of their loved one’s distress at the EOL. Interventions to optimize EOL care for patients and reduce bereaved caregivers’ psychological distress are needed.
Professor Grancher's Work on Early Diagnosis of Tuberculosis.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Carboplatin is effective therapy for young children with progressive optic pathway tumors: A Pediatric Oncology Group phase II study
Authors: Donald H. Mahoney, Michael E. Cohen, Henry S. Friedman, James L. Kepner, Linda Gemer, James W. Langston, Hector E. James, Patricia K. Duffner, Larry E. Kun
Journal: Neuro-Oncology (2000)

The Pediatric Oncology Group conducted a phase II study to evaluate the activity of carboplatin in children 5 years or younger with progressive optic pathway tumors (OPTs).Of the 51 patients accrued to this study, 1 was not eligible because the child was older than 6 years.Fifty patients were eligible and had either neuro-imaging or symptomatic evidence of progressive OPTs.Twenty-one of 50 had evidence of neuro bromatosis type I (NF-1).Therapy consisted of carboplatin 560 mg/m 2 at 4-week intervals.Patients with stable disease or better after two courses were continued on therapy for 18 months or until progressive disease.Of the 50 eligible children, 39 had stable disease or better, and 34 completed the 18-month therapy.Our data are suf cient to conclude that the proportion of objective responses (complete, partial, or minor response or stable disease) exceeded 30% (P < 0.00001), and the approximate 95% con dence interval estimate of the objective response rate was 0.665 to 0.895.Twentyone patients went off protocol because of progressive disease.Fifteen patients progressed during the 18-month therapy, and 6 patients progressed after completing therapy.Six children died with progressive disease.Major toxicities were neutropenia and thrombocytopenia, and 3 children experienced allergic reactions.Carboplatin is active and safe for the treatment of young children with progressive OPTs.The addition of other potentially active drugs may further increase the event-free survival for these children.
Any Abnormality in Lung X-ray Important to Cancer Detection
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal