tbuckley/cabot-search huggingface dataset:
Primary empty sella syndrome with CSF rhinorrhea
Authors: E. L. Applebaum
Journal: JAMA (1980)

BUSCH<sup>1</sup>originally used the term "empty sella" for autopsy cases in which the pituitary gland formed only a thin layer of tissue at the bottom of the sella turcica with associated absence, or incompetence, of the diaphragma sellae. Lee and Adams<sup>2</sup>used the term "empty sella syndrome" when referring to patients with pituitary tumors treated by surgery or radiation therapy who later had visual dysfunction without evidence of tumor recurrence. In 1968, Ommaya et al<sup>3</sup>reported the first two cases of CSF rhinorrhea associated with the empty sella syndrome. <h3>Report of a Case</h3> A 52-year-old, moderately obese, hypertensive woman was seen at the Illinois Eye and Ear Infirmary, Chicago, with unilateral, left-sided, watery rhinorrhea of six months' duration. Three months previously, she had been treated for meningitis in another hospital and discharged without evaluation of the nasal discharge. There was no history of head trauma. A left-sided, profuse,
Family Heroes
Authors: Lynn S. Bemiller
Journal: Annals of Internal Medicine (2013)

Ad Libitum2 April 2013Family HeroesLynn S. Bemiller, MD, MPHLynn S. Bemiller, MD, MPHFrom South County Hematology and Oncology, San Diego, California.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-158-7-201304020-00013 Audio Reading - "Family Heroes" Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Family Heroes," by L.S. Bemiller. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail My elegant Southern grandmother was almost 90 years old when complications from endometrial cancer therapy left her too frail to live on her own. My father, overwhelmed with caregiving, called us grandchildren in from around the country to help him move our platinum magnolia from her Austin home, filled with antiques and collected artifacts from around the world, to an assisted-living complex where many of her friends already lived.Owing to my lifelong fascination with family roots, my father put me in charge of sorting generations of family papers, pictures, Bibles, yearbooks, and a miscellany of family artifacts, including a ... Author, Article, and Disclosure InformationAffiliations: From South County Hematology and Oncology, San Diego, California.Current Author Address: Lynn S. Bemiller, MD, MPH, South County Hematology and Oncology, 769 Medical Center Court, Suite 202, Chula Vista, CA 91911; e-mail, [email protected]com. PreviousarticleNextarticle Advertisement Audio Reading - "Family Heroes" Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "Family Heroes," by L.S. Bemiller. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 2 April 2013Volume 158, Issue 7Page: 567KeywordsEngineersGraduate medical educationHeartHematology and oncology ePublished: 2 April 2013 Issue Published: 2 April 2013 Copyright & PermissionsCopyright © 2013 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Advanced cancer patients’ reported priorities regarding wishes at the end of life: A randomized controlled study.
Authors: Marvin Omar Delgado-Guay, Vera J De la Cruz, Susan Frisbee-Hume, Janet L. Williams, Jimin Wu, Diane D Liu, Michael Fisch, Eduardo Bruera
Journal: Journal of Clinical Oncology (2015)

9546 Background: Conversations about wishes around the end-of-life(EOL) are challenging and difficult for all clinicians. There is limited literature about the type and stability of patient’s reported EOL priorities. We compared a set of 36 cards (“Go-wish-Game”:GWG) v. a paper list to assist patients in establishing priorities. Methods: Randomized controlled study. Patients were randomized to GWG or to a list of 36 Wishes/Statements(LOS) and were asked to categorize them as very, somewhat, or not important; Group A received LOS followed by LOS 4-24 hours later; group B: GWG-GWG; group C: GWG-LOS, and group D: LOS-GWG. The State-Trait Anxiety inventory for Adults (STAI) was done after the first set of questionnaires. Results: 100 patients. Median age (IQR range): 56(27-83)years. 60% female. 68% White, 17% Hispanic, and 9% African-American. Age, education and cancer diagnosis weren't significant different among groups. All patients were able to complete GWG. 43/50(88%) agreed GWG had clear instructions and easy to understand (92%). 31/50(63%) patients exposed to both tools, preferred GWG. 31/50(63%) expressed having conversations about priorities near EOL was beneficial to them. STAI median (IQR) score after GWG was 48(39-59) v. 47(27-63) for LOS, p = 0.2952. 39/50(80%) expressed that GWG did not increased their anxiety. The 10 most common “Very important” wishes expressed by patients the first and second time they received the test(%; Spearman, p-value) were: to be at peace with God(74% v. 71%; r = 0.73, p < 0.0001), to pray(62% v. 61%, r = 0.53, p < 0.0001), to have my family with me(57% v. 61%; r = 0.23, p = 0.02), to be free from pain(54% v. 60%, r = 0.31, p = 0.001), not being a burden to my family(48% v. 49%, r = 0.23, p = 0.02), to trust my doctor(44% v. 45%; r = 0.49, p < 0.0001), to keep my sense of humor(41% v. 45%; r = 0.53, p < 0.0001), to say goodbye to important people in my life(41% v. 37%; r = 0.46, p < 0.0001); to have my family prepared for my death(40% v. 49%; r = 0.48, p < 0.0001), and to be able to help others(36% v. 31%; r = 0.73, p < 0.0001). Conclusions: End-of-life wishes were similar and persistent using both GWG and LOS. All patients were able to complete and most preferred GWG. Completing both GWG and LOS did not increase anxiety.
ADOLF KUSSMAUL (1822-1902)—COUNTRY DOCTOR TO CLINICAL PROFESSOR
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The accuracy of drug information from pharmaceutical sales representatives
Authors: M. G. Ziegler
Journal: JAMA (1995)

<h3>Objective.</h3> —To provide quantitative data about the accuracy of the information about drugs presented to physicians by pharmaceutical sales representatives. <h3>Design.</h3> —One hundred six statements about drugs made during 13 presentations by pharmaceutical representatives were analyzed for accuracy. Statements were rated inaccurate if they contradicted the 1993<i>Physicians' Desk Reference</i>or material quoted or handed out by the sales representative. <h3>Setting.</h3> —University teaching hospital. <h3>Results.</h3> —Twelve (11%) of 106 statements about drugs were inaccurate. All 12 inaccurate statements were favorable toward the promoted drug, whereas 39 (49%) of 79 accurate statements were favorable (<i>P</i>=.005). None of 15 statements about competitors' drugs were favorable, but all were accurate, significantly (<i>P</i>&lt;.001) differing from statements about promoted drugs. In a survey of 27 physicians who attended these presentations, seven (26%) recalled any false statement made by a pharmaceutical representative, and 10 (37%) said information from the representatives influenced the way they prescribed drugs. <h3>Conclusions.</h3> —Eleven percent of the statements made by pharmaceutical representatives about drugs contradicted information readily available to them. Physicians generally failed to recognize the inaccurate statements. (<i>JAMA</i>. 1995;273:1296-1298)
Psychotherapeutic Approach
Authors: W. Sargant
Journal: BMJ (1966)

BDICALJRNAL basis of inheritance, molecular genetics, the regulation and control of genes, chromosomal aberration, the Lyon hypothesis, and poly- morphism.There is a valuable chapter on immunogenetics with its important applica- tion to transplantation surgery and auto- immune disease.Haemolytic disease of the newborn is adequately explained, but no reference is made to the recent advances in prophylaxis of this condition.There are over 80 well-chosen illustrations in addition to many tables and diagrams.Throughout the text references are few, but a short list of key references is given at the end of each chapter.A few minor criticisms can be made.The authors, on page 105, state that the risk to a mother with one child with Down's syn- drome having further affected children is three times the risk for any mother of a similar age.Such advice is too pessimistic, especially in the older age groups.The risk to any woman over 35 years with one affected child is probably no greater than 1 in 50.The book can be thoroughly recommended to medical students, but undoubtedly it will enjoy a much wider appeal.
The Association of Chromium in Household Dust with Urinary Chromium in Residences Adjacent to Chromate Production Waste Sites
Authors: Alan H. Stern, Jerald A. Fagliano, Jonathan E. Savrin, Natalie C. G. Freeman, Paul J. Lioy
Journal: Environmental Health Perspectives (1998)

This paper describes a research partnership between the people of Akwesasne and researchers from the State University of New York at Albany for the study of polychlorinated biphenyls and the health of Mohawk youth. The study is distinctive because its goals have been set by the scientists and the community members and is being conducted jointly by these groups. The research partnership recognizes the history of relationships between native and nonnative peoples, particularly scientists, and seeks not only to fulfill certain scientific goals but to further community ones as well. The relationship is based on three principles: mutual respect, mutual equity, and mutual empowerment. These principles guided every aspect of the research process. The project goals were determined jointly to maximize data quality and minimize the intrusion of research activities into the lives of community members. Data collection is performed by research assistants who received extensive and ongoing training in data collection methods, and who are members of the community. Feedback procedures were designed by community members and scientists jointly to maximize understanding. Feedback regarding individuals' pollutant levels and assessments of growth and development are provided to each individual. Information about community pollutant levels are provided to the community. Hypothesis testing is carried out by research scientists, and the results presented first at a community meeting. Research conducted in this way--as a partnership--requires more communication, discussion, and travel, but the result is mutual satisfaction and growth.
Holism
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The measurement of exhaled carbon monoxide is influenced by airflow obstruction
Authors: B. Togores, M. Bosch, A.G.N. Agustí
Journal: European Respiratory Journal (2000)

The concentration of carboxyhaemoglobin (COHb) is often estimated from measurements of carbon monoxide in the exhaled air (COexh). This study investigates whether the presence of airflow obstruction significantly alters the relationship between COexh and COHb. Eighty-one regular smokers were prospectively studied and divided in four groups according to the presence and severity of airflow obstruction (none, mild, moderate, severe). In each subject, the authors measured in this order: 1) arterial blood gases; 2) haemoglobin concentration and COHb (by co-oxymetry); 3) COexh; 4) lung volumes; and 5) forced spirometry. The size of the measurement error (deltaCO) was calculated from the difference between COHb and COexh. Neither the smoking history nor COexh were different in the four groups of subjects studied. In contrast, deltaCO increased in parallel to the degree of airflow obstruction. DeltaCO was &gt;2% (a threshold value normally used in the clinic to separate smokers from nonsmokers) only in patients with severe airflow obstruction. A stepwise multivariate analysis showed that both forced expiratory volume in one second (FEV1) (percentage reference) and COHb contributed significantly (p&lt;0.0001) to predict deltaCO. This study shows that the estimation of carboxyhaemoglobin from exhaled carbon monoxide measurements can be inaccurate in patients with severe airflow obstruction. In these patients, the direct measurement of carboxyhaemoglobin seems advisable in clinical practice.
Gout. Its Etiology, Pathology and Treatment.
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pruritus
Authors: E. Michael Lewiecki
Journal: JAMA (1976)

PRURITUS as a manifestation of iron deficiency, to the best of our knowledge, has not been described. The following report presents such a case. <h3>Report of a Case</h3> A 62-year-old woman was seen in the outpatient clinic in August 1975, with a six-month history of generalized itching that had recently become more severe. Her only medications were conjugated estrogens and occasional aspirin. Results of a physical examination and a dermatological examination were normal. She was treated with diphenhydramine hydrochloride, with no relief of itching. At a follow-up clinic visit, psychogenic itching was diagnosed, and her medication was changed to meprobamate. In December 1975, she was seen again complaining of unrelieved itching, shortness of breath, and chest pain characteristic of angina pectoris. She had stopped taking meprobamate a few weeks previously, since it did not relieve her pruritus. Present medications were conjugated estrogens and aspirin. Findings from a physical examination showed
Laser-induced hemostasis in the canine stomach. Use of a flexible fiberoptic delivery system
Authors: R. M. Dwyer
Journal: JAMA (1975)

A flexible fiberoptic system has been used to deliver visible laser light into the upper gastrointestinal tract to arrest bleeding from various induced lesions. This procedure has achieved hemostasis at bleeding sites in the gastrointestinal tract of animals and suggests that bleeding lesions in the human may be treated similarly without resort to surgical intervention or intensive medical management. (<i>JAMA</i>231:486-489, 1975).
Rheumatoid Arthritis
Authors: Robert J. Quinet
Journal: JAMA (2009)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Neurology
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
SCID takes many forms; infection common
Authors: K. Simmons
Journal: JAMA (1984)

Severe combined immunodeficiency (SCID), the most severe of the 30 to 40 primary immunodeficiency diseases, is really "a number of diseases," says Michael Blaese, MD. Blaese, who is a clinical pediatric immunologist and chief of the Cellular Immunology Section of the Metabolism Branch, National Cancer Institute, Bethesda, Md, points out that there are at least a half dozen to a dozen different forms of SCID. One reason is that SCID can arise sporadically as well as genetically from two different inheritance patterns: X-linked recessive (as with Houston's David) or autosomal recessive (appearing with or without a deficiency in adenosine deaminase). Some forms are more common than others; a deficiency in adenosine deaminase, for example, occurs in only about 15% of SCID cases. "Even within SCID, there are different kinds of problems," Blaese said in an interview with<i>JAMA</i>MEDICAL NEWS. "Some people make abnormal enzymes, some of them lack the
Letter: Sociological realities.
Authors: N Prichard
Journal: BMJ (1976)

the UK ?In many countries the cost of alcohol-induced problems exceeds the revenue raised from alcohol taxation.7Let not anyone, even members of Parlia- ment, be surprised that if you give more of a drug you get a greater response.Whatever special aetiological factor-for example, genetic -there may be in alcoholism, this overall doseresponse relationship with alcohol and its effects on society are established with a high degree of probability.I do not think that the experiment that the legislators seemed poised to carry out would pass any hospital ethical committee; it's been done before and the risk of a high incidence of adverse effects is too great.
Cover Page
Journal: Neuro-Oncology (2013)

Additional criteria apply.Please refer to protocol 14379-201 for full inclusion and exclusion criteria.† Patients can participate if they had some skin cancers, superficial bladder cancer (cancer that was only on the surface of the lining of the bladder), or carcinoma in situ (cancer that had not spread) of the cervix or breast that had been cured.HIV, human immunodeficiency virus; HBV, hepatitis B virus; HCV, hepatitis C virus; IGF-1R, insulin-like growth factor 1 receptor; KPS, Karnofsky Performance Scale; RT, radiotherapy; SOC, standard of care; TMZ, temozolomide.