tbuckley/cabot-search huggingface dataset:
Correction to: Global, Regional, and National Burden of Calcific Aortic Valve and Degenerative Mitral Valve Diseases, 1990–2017
Journal: Circulation (2020)

incorrectly reported the number of DALYs attributable to NRVD, the percent of all cause DALYs attributable to NRVD, and the percent change in number of DALYs between 1990 and 2017 for CAVD and DMVD.These values have been corrected in the final version of this article to 2.5 million (95% UI, 2.3-2.8 million) DALYs attributable to NRVD, 0.10% (95% UI, 0.09%-0.11%) of all cause DALYs attributable to NRVD, and 101% (95% UI, 79%-117%) and 35% (95% UI, 23%-47%) change in number of DALYs between 1990 and 2017 for CAVD and DMVD, respectively.The percent change in the number of prevalent cases of DMVD between 1990 and 2017 was also incorrectly reported as 58% (95% UI, 53%-63%), and has been corrected to 94% (95% UI, 94%-95%) in the final
HIV infection in patients attending clinics for sexually transmitted diseases in England and Wales. Collaborative Study by Consultants in Genitourinary Medicine and the Public Health Laboratory Service.
Authors: Sheila Polakoff
Journal: BMJ (1989)

A national study of the prevalence of HIV antibody designed to monitor sexual spread of HIV infection in England and Wales was made of homosexual and heterosexual patients attending sexually transmitted disease clinics in four districts in 1985, seven in 1986, and 14 in 1987. Patients were invited to participate and were counselled. Among homosexual men in two clinics in south east England, HIV antibody was found in 92 (12.9%) of 711 in 1985, 65 (15.2%) of 428 in 1986, and 81 (14.6%) of 556 in 1987: corresponding findings in the other regions were 16 (5.0%) of 321, 41 (6.3%) of 654, and 21 (3.1%) of 678. The prevalence of HIV antibody was higher in homosexual than bisexual men, in patients aged 25 years or more, or with one or more specified minor complaints. Among heterosexual patients in the south east in 1986, HIV antibody was found in seven (3.0%) of 230 men and three (1.3%) of 233 women and in 1987 in 10 (1.0%) of 962 men and seven (0.7%) of 949 women. In other areas corresponding findings in 1986 were two (0.2%) of 950 men and three (0.4%) of 752 women and in 1987 were three (0.06%) of 5312 men and one (0.02%) of 4778 women. All but one of the heterosexual patients with the antibody were intravenous drug abusers or had had sexual contacts in or were from an area abroad with a high prevalence of AIDS. Failure to identify a heterosexual patient with HIV antibody not in a risk group (other than that of being an attender at the clinic) or who did not have a sexual partner in a risk group suggests that their prevalence in the patient population of the clinics in the south east is less than one in 700 and in the other regions less than one in 3000. Refusals to participate increased during the study but comparisons of patients who agreed and refused in terms of age, the presence of symptoms suggesting AIDS, travel abroad, and number of sexual partners a month showed little evidence of selective bias.
PPARγ1 attenuates cytosol to membrane translocation of PKCα to desensitize monocytes/macrophages
Authors: Andreas von Knethen, Mathias Soller, Nico Tzieply, Andreas Weigert, Axel M. Johann, Carla Jennewein, Roman Köhl, Bernhard Brüne
Journal: The Journal of Experimental Medicine (2007)
Membrane Cofactor Protein (Mcp Or Cd46): Newest Member Of The Regulators Of Complement Activation Gene Cluster
Authors: M. Liszewski
Journal: Annual Review of Immunology (1991)

Exhausted CD8 T (Tex) cells are a distinct cell lineage that arise during chronic infections and cancers in animal models and humans. Tex cells are characterized by progressive loss of effector functions, high and sustained inhibitory receptor expression, ...Read More
Manual promotes self-care for chemotherapy's effects
Authors: B. Bolsen
Journal: JAMA (1982)

Would patients with cancer be better able to cope with the side effects of chemotherapy if they knew more about their drugs, the side effects they cause, and techniques for managing them at home? Marilyn Dodd, RN, PhD, professor of nursing, University of California, San Francisco, thinks so, and says that a pair of studies she conducted in Detroit and San Francisco have confirmed her beliefs. While a doctoral candidate at Wayne State University, Detroit, Dodd worked privately as a nurse practitioner with cancer patients who had been discharged from hospitals and were receiving chemotherapy. "They were being sent home with no idea of 'What can I do for myself when I get sick?'" she said. To investigate the situation further, Dodd wrote to the nation's 19 comprehensive cancer centers, seeking patient information. She received in return "random sheets of little notes containing information that was badly dated, global, and
Nuclear studies in human pituitary glands of varying weights
Authors: S. B. Fand
Journal: JAMA (1967)

The endocrine glands react to demands for increased hormone production by an increase in their functional size and their weight. Thus, the thyroid, the adrenal, and the parathyroid glands are known to enlarge demonstrably in the syndromes associated with their increased hormone production. The pituitary, too, is generally considered to react in this manner, and increased pituitary size has been reported, for example, in primary myxedema and following adrenalectomy for Cushing's syndrome: in both instances there is presumably a compensatory increase in tropic hormone output by the pituitary—thyroid stimulating hormone in the first, adrenocorticotrophic hormone in the second. Evidence of a correlation between decreasing size and reduced hormone output can be seen in steroid-treated patients where a diminution in pituitary size—associated with decreased tropic hormone release—may well be the rule. These examples of reactive changes in pituitary size and weight in the human could be challenged; pituitary size increase in
What Brings on Insulin Sensitivity?
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Physical fitness and incidence of hypertension in healthy normotensive men and women
Authors: S. N. Blair
Journal: JAMA (1984)

We measured physical fitness, assessed by maximal treadmill testing in 4,820 men and 1,219 women aged 20 to 65 years. Participants had no history of cardiovascular disease and were normotensive at baseline. We followed up these persons for one to 12 years (median, four years) for the development of hypertension. Multiple logistic risk analysis was used to estimate the independent contribution of physical fitness to risk of becoming hypertensive. After adjustment for sex, age, follow-up interval, baseline blood pressure, and baseline body-mass index, persons with low levels of physical fitness (72% of the group) had a relative risk of 1.52 for the development of hypertension when compared with highly fit persons. Risk of hypertension developing also increased substantially with increased baseline blood pressure. (<i>JAMA</i>1984;252:487-490)
FRI0412 Symptoms of Attention Deficit Hyperactivity Disorder in Patients with Systemic Lupus Erythematosus
Authors: Y. Gao, Y. Lo, M.Y. Mok
Journal: Annals of the Rheumatic Diseases (2015)

<h3>Background</h3> Cognitive function and mood disturbance are common in patients with systemic lupus erythematosus (SLE). <h3>Objectives</h3> This study aims to examine whether SLE patients have more features of adult attention deficit hyperactivity disorder (ADHD) and their relation to anxiety and depressive symptoms. <h3>Methods</h3> Symptoms and clinically significant items of the inattention and hyperactivity/impulsivity domains of ADHD were examined in Part A and Part B by the screening instrument of ADHD Self-Reported Scale (ASRS) respectively. Anxiety and depressive symptoms were measured by HADS-A and HADS-D respectively. <h3>Results</h3> There were no differences in symptom scores of inattention and hyperactivity/impulsivity between inactive SLE patients (n=117) and age- and sex- matched controls (n=64). However, SLE patients had more clinically significant items in the inattention domain compared with controls (p=0.006), particularly among those who had previous cerebral involvement (p=0.004). Patients who had psychiatric diseases had more clinically significant items of the hyperactivity/impulsivity domain (p=0.006). Possible ADHD was found in 7.7% of SLE and 6.3% of healthy subjects (p=1.00) by the screening tool. Patients with higher inattention symptom scores were more likely to be unemployed but not for duration of education and smoking habit. Anxiety and depressive symptoms correlated with ADHD symptoms. HADS-A was independent predictive factor for clinically significant symptoms of inattention (p&lt;0.001) and hyperactivity/impulsivity (p=0.04) by logistic regression. <h3>Conclusions</h3> Inactive SLE patients, particularly those who had previous cerebral lupus, had more clinically significant symptoms of inattention but not hyperactivity/impulsivity reflecting underlying cognitive impairment. Anxiety and depressive symptoms were common confounders for ADHD-like symptoms. <h3>Disclosure of Interest</h3> None declared
评估湿疹的 Rajka 和 Langeland 评分有多好?
Journal: British Journal of Dermatology (2021)

特应性皮炎 (AD) 是各年龄段人群 (尤其是儿童) 身上一种常见的湿疹类型。它会造成皮肤发炎、发痒和酸痛, 并影响日常生活的许多方面。关于不同治疗方法的研究很多, 但很难对其进行比较, 因为研究人员使用不同的方法来评定湿疹的严重程度。
Outpatient 180 W XPS GreenLight™ Laser photoselective vaporization of the prostate: Seven year experience
Authors: J. Chavarriaga Soto, J.C. Erazo, D. Suso, J. Sejnaui, L. Aluma, L. Mendoza, G. Ramirez, C. Morales, F. Usubillaga, S. Mendoza, F. Rivera, A. Mendoza, M.C. Usubillaga, S. Erazo
Journal: European Urology (2021)
MEDICAL HELP IN THE UNDERNUTRITION OF CHILDHOOD—WHAT NEXT?
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 2368: Baseline Dietary Glycemic Load as a Predictor of Weight Loss on the Atkins, Zone, Weight Watchers and Ornish Diets.
Authors: Aaron F Buchsbaum, Ernst J Schaefer, Michael L Dansinger
Journal: Circulation (2007)

Background: Methods for matching patients with optimal diets are lacking. We previously reported that 4 popular diets (Atkins, Zone, Weight Watchers and Ornish), which range from low to high in dietary carbohydrate and glycemic load, produced similar 1-year weight loss in a randomized trial. We tested the hypothesis that dietary glycemic load at baseline (prior to dietary intervention) would affect the magnitude of weight loss from each diet. Methods: We randomized 160 overweight and obese adults (mean BMI=35) to follow the Atkins, Zone, Weight Watchers, or Ornish dietary advice. Participants attempted maximum dietary adherence and attended 4 small-group classes during the first 2 months, then self-selected dietary adherence levels for the following 10 months. One-year weight loss for each diet was determined according to tertiles of baseline dietary glycemic load, assessed by 3-day food records, nutrition analysis software, and published glycemic index tables. Missing data were replaced with baseline values in an intent-to-treat analysis (n=40 per diet). Results: The association between 1-year weight loss and dietary glycemic load at baseline differed significantly according to diet type (p&lt;.01 for interaction). Participants in the highest tertile of dietary glycemic load at baseline had greater weight loss on lower carbohydrate diets (−4.6 kg, −4.6 kg, −2.1 kg, −1.5 kg for Atkins, Zone, Weight Watchers, and Ornish, respectively; p=0.05 for linear trend), and participants in the lowest tertile of dietary glycemic load at baseline had greater weight loss on higher carbohydrate diets (+0.3 kg, −1.0 kg, −3.2 kg, −5.3 kg for Atkins, Zone, Weight Watchers, and Ornish, respectively; p=0.01 for linear trend). For the middle tertile of baseline dietary glycemic load, weight loss did not differ between diets (−1.7 kg, −4.1 kg, −3.8 kg, −1.5 kg for Atkins, Zone, Weight Watchers, and Ornish, respectively, p=0.6 for linear trend, p=0.3 for two highest vs. two lowest). Conclusions: Dietary glycemic load intake prior to dietary intervention may impact the effectiveness of popular diets for weight loss, and may be an important consideration in optimal diet selection for individual patients. These results should be verified in other study populations.
Oral Methadone Maintenance Techniques in the Management of Morphine-Type Dependence
Journal: JAMA (1972)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
News about the United European Gastroenterology Federation
Authors: P. L. Jansen, P. Milla
Journal: Gut (1996)

The UK Renal Registry currently collects information on UK children with kidney failure requiring long-term kidney replacement therapy (KRT), which supports disease surveillance and auditing of care and outcomes; however, data are limited on children with chronic kidney disease (CKD) not on KRT. <h3>Methods</h3> In March 2020, all UK Paediatric Nephrology centres submitted data on children aged &lt;16 years with severely reduced kidney function as of December 2019, defined as an estimated glomerular filtration rate &lt;30 mL/min/1.73 m<sup>2</sup>. <h3>Results</h3> In total, 1031 children had severe CKD, the majority of whom (80.7%) were on KRT. The overall prevalence was 81.2 (95% CI 76.3 to 86.3) per million of the age-related population. <h3>Conclusions</h3> The prevalence of severe CKD among UK children is largely due to a high proportion of children on long-term KRT. Expanding data capture to include children with CKD before reaching failure will provide greater understanding of the CKD burden in childhood.
DENMARK
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Down Syndrome
Authors: Ian B. Shine
Journal: JAMA (1973)

<h3>To the Editor.—</h3> The name of Adrian Bleyer has long been buried among the footnotes of the medical history of Down syndrome. Many who were repeatedly wrong about mongolism have been duly hailed for changing their minds, but history seems to have forgotten this American physician, even though he was right quite early in the game. Bleyer's most notable work<sup>1</sup>was read before the St. Louis Pediatric Society on December 16, 1932. He reasoned (1) that every body organ seemed involved in the disorder, and (2) that while all single ovum twins were both mongols, double ovum twins were not; he concluded that "Mongolism occurs with fertilization or has already occurred before it during the period of maturation either of the ovum or of the spermatozoon..." Pursuing this thought, he drew upon the geneticist Herbert Walter's discussion of abnormal chromosomes: "During the period of unpairing of homologous chromosomes... a piece
Adenosine: A Physiological Brake On Renin Release
Authors: E. Jackson
Journal: The Annual Review of Pharmacology and Toxicology (1991)

Heme oxygenases (HO) catabolize free heme, that is, iron (Fe) protoporphyrin (IX), into equimolar amounts of Fe2+, carbon monoxide (CO), and biliverdin. The stress-responsive HO-1 isoenzyme affords protection against programmed cell death. The mechanism ...Read More
BOOK REVIEWING.
Journal: JAMA (1890)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INTERNATIONAL CONGRESS AT ROME NOT ADJOURNED.
Journal: JAMA (1893)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medicaid and prenatal care. Necessary but not sufficient
Authors: B. Guyer
Journal: JAMA (1990)

The findings reported by Piper and colleagues<sup>1</sup>that appear in this issue ofThe Journalshould not be baffling or discouraging to policymakers concerned with reducing the nation's infant mortality rate. The authors evaluate the effects in Tennessee of the first of a series of expansions in Medicaid eligibility that were intended to improve the outcome of pregnancy among women with low incomes. This report, and others that will surely follow, should help shape future maternal and child health financing policies. Since the early 1980s, Congress has repeatedly amended Medicaid (Omnibus Budget Reconciliation Act, 1981, 1986, 1987, and 1989; Deficit Reduction Act, 1984; Consolidated Omnibus Budget Reconciliation Act, 1985; and Catastrophic Care, 1988) to expand incremental eligibility for pregnant women and infants.<sup>2</sup>Congress initially conceptualized infant mortality as a problem of access to health care. Congressional action was influenced by the findings of the Institute of Medicine's Committee