tbuckley/cabot-search huggingface dataset:
Rabies Infection
Journal: JAMA (1977)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Melioidosis pneumonitis. Analysis of nine cases of a benign form of melioidosis
Authors: M. Spotnitz
Journal: JAMA (1967)

Melioidosis has been known as a highly fatal bacterial infection of tropical areas. Epidemiological studies indicate that the disease is much more common than previously suspected because a high incidence of asymptomatic infections was found among natives of the endemic areas. In nine patients in whom the infection was confined to the lungs, the clinical manifestations closely mimicked pulmonary tuberculosis with upper-lobe infiltration and cavitation. The course was subacute, the patients had a productive cough, blood-tinged sputum, chest pain, fever, chills, weight loss, and anemia. This form of the disease showed an excellent response to appropriate antibiotic therapy. Isolated pulmonary melioidosis is a relatively benign disease and does not have the same prognosis as the septicemic form.
Influence of coronary atherosclerotic remodeling and plaque characteristics on mechanisms of lumen enlargement during stent implantation Gerard Finet, Neil J. Weissman, Marco T. Castagna, Kenneth M. Kent, Lowell F. Satler, John R. Laird, Augusto D. Pichard. Washington Hospital Center, Washington, DC
Journal: Journal of the American College of Cardiology (2001)
BOOK REVIEWS
Authors: L. MORRIS
Journal: JNCI Journal of the National Cancer Institute (1991)

Journal Article BOOK REVIEWS Get access Manual of Clinical Oncology, 5th ed . D.K. Hossfeld , C. D. Sherman , R. R. Love , F. X. Bosch , eds. Berlin : Springer-Verlag , 1990 , 391 pp.$56. LAWRENCE MORRIS, JR LAWRENCE MORRIS, JR Johns Hopkins Oncology Center600 N Wolfe St Baltimore, MD 21205 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 83, Issue 10, 15 May 1991, Pages 722–723, https://doi.org/10.1093/jnci/83.10.722 Published: 15 May 1991
The hypertensive patient. An algorithm for treatment
Authors: R. F. Maronde
Journal: JAMA (1975)

THE GOAL of the physician in the treatment of the hypertensive patient should be to achieve a blood pressure as near normal as possible with minimal adverse drug effects. Therapeutic compliance by the patient is inversely related to the severity of reactions attributed to medication. Patients frequently will not volunteer such information. Questioning in some detail by the physician may be required to assess correctly the degree of patient compliance. <h3>Indications for Hospitalization</h3><h3>Diastolic Pressure of 135 mm Hg.—</h3> Patients with a diastolic pressure of 135 mm Hg or higher, or patients with retinal hemorrhages or papilledema, should be hospitalized and treated promptly. If papilledema is present or if the diastolic pressure is sustained at levels of 150 mm Hg or higher, parenteral therapy with diazoxide or hydralazine hydrochloride or sodium nitroprusside should be instituted. Diazoxide should be given in a bolus intravenously. Hydralazine and sodium nitroprusside are given by
How should physicians be paid?
Authors: G. D. Lundberg
Journal: JAMA (1985)

The medical profession is now undergoing tumultuous and rapid changes that are largely economic. Drastic changes are occurring in payment schemes for hospital care, followed by numerous proposals for changing the method of paying physicians. In earliest days, doctors performed their healing services without pay. But ordinary man must eat to live, so the practice of doctoring became compensable. In his article "XXII. Medical Practice: Making a Living," Lester King describes 19th-century methods of compensating physicians in the United States.<sup>1</sup> Health insurance does not stem from antiquity; its beginnings may be traced to 18th- or 19th-century Germany. Before health insurance, patients who were able to do so paid doctors out of their pockets and often paid on installment plans. Those who could not pay were charity cases. This system worked well for routine care but not so well when it came to large expenses. So a system of health
Official Call
Authors: Donovan F. Ward
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Higher proportion of responders with hepatitis B antibody levels ≥ 100 miu/ml with the trivalent HepB vaccine, Sci-B-Vac, compared to Engerix-B: results from the phase 3 double-blind, randomized study comparing immunogenicity and safety (PROTECT)
Authors: Timo Vesikari, Joanne Langley, Nathan Segall, Brian Ward, Curtis Cooper, Guillaume Poliquin, Soren Gantt, Bruce Smith, Pierre Van Damme, Isabel Leroux-Roels, Geert Leroux-Roels, Nathalie Machluf, Johanna Spaans, Bebi Yassin-Rajkumar, David Anderson, Vlad Popovic, Francisco Diaz-Mitoma
Journal: Journal of Hepatology (2020)
Digital image analysis for quantitative evaluation of fibrosis, steatosis, inflammation and iron overload in patients with non-alcoholic fatty liver disease
Authors: David Marti-Aguado, Alejandro Rodríguez-Ortega, Claudia Mestre, Monica Bauza, Elena Valero-Pérez, Judith Pérez, Antonio Ferrández, Salvador Benlloch, Desamparados Escudero-Garciá, Miguel Serra, Angel Alberich-Bayarri, Luis Marti-Bonmati
Journal: Journal of Hepatology (2020)
Venous Thromboembolism Prophylaxis and Treatment in Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update
Authors: Gary H. Lyman, Alok A. Khorana, Nicole M. Kuderer, Agnes Y. Lee, Juan Ignacio Arcelus, Edward P. Balaban, Jeffrey M. Clarke, Christopher R. Flowers, Charles W. Francis, Leigh E. Gates, Ajay K. Kakkar, Nigel S. Key, Mark N. Levine, Howard A. Liebman, Margaret A. Tempero, Sandra L. Wong, Ann Alexis Prestrud, Anna Falanga
Journal: Journal of Clinical Oncology (2013)

To provide recommendations about prophylaxis and treatment of venous thromboembolism (VTE) in patients with cancer. Prophylaxis in the outpatient, inpatient, and perioperative settings was considered, as were treatment and use of anticoagulation as a cancer-directed therapy.A systematic review of the literature published from December 2007 to December 2012 was completed in MEDLINE and the Cochrane Collaboration Library. An Update Committee reviewed evidence to determine which recommendations required revision.Forty-two publications met eligibility criteria, including 16 systematic reviews and 24 randomized controlled trials.Most hospitalized patients with cancer require thromboprophylaxis throughout hospitalization. Thromboprophylaxis is not routinely recommended for outpatients with cancer. It may be considered for selected high-risk patients. Patients with multiple myeloma receiving antiangiogenesis agents with chemotherapy and/or dexamethasone should receive prophylaxis with either low-molecular weight heparin (LMWH) or low-dose aspirin. Patients undergoing major cancer surgery should receive prophylaxis, starting before surgery and continuing for at least 7 to 10 days. Extending prophylaxis up to 4 weeks should be considered in those with high-risk features. LMWH is recommended for the initial 5 to 10 days of treatment for deep vein thrombosis and pulmonary embolism as well as for long-term (6 months) secondary prophylaxis. Use of novel oral anticoagulants is not currently recommended for patients with malignancy and VTE. Anticoagulation should not be used for cancer treatment in the absence of other indications. Patients with cancer should be periodically assessed for VTE risk. Oncology professionals should provide patient education about the signs and symptoms of VTE.
Phase I/II trial of gemcitabine plus treosulfan (GeT) in stage IV uveal melanoma and carcinomas
Authors: A. H. Schmittel, R. Schuster, N. Bechrakis, J. Siehl, M. H. Foerster, E. Thiel, U. Keilholz
Journal: Journal of Clinical Oncology (2004)

7525 Background: To define the maximum tolerated dose (MTD) of treosulfan in combination with a fixed dose of gemcitabine and to estimate clinical efficacy in uveal melanoma patients. Preclinical studies suggested synergistic activity of both agents against uveal melanoma. Methods: Gemcitabine (1g/m2) and treosulfan (2.5g/m2 - 4g/m2) were administered on days 1 and 8 of a 4 week cycle for a maximum of 6 cycles. Dose escalation cohorts of 2–4 patients were enrolled. Additional patients were entered on treosulfan dose levels II (3 g/m2) and III (3.5 g/m2). Results: A total of 131 cycles were administered to 33 patients with metastatic uveal melanoma and 6 patients with metastatic carcinomas. Dose limiting toxicity (DLT) was thrombopenia and leucopenia. The maximum tolerated dose (MTD) was 3.5g of treosulfan and 1g of gemcitabine. Efficacy can be estimated in ocular melanoma patients. One partial remission (PR) was observed. Surprisingly, even with the small patient number a significant trend for improved overall survival (OS) with higher treosulfan doses was observed (p=0.04), with a median OS of 6 vs. 8.5 months and a one year survival rate of 7.1% vs. 30.7% at treosulfan doses of ≤3g/m2 and ≥3.5g/m2, respectively. A strong pre-treatment prognostic factor was the serum LDH level, which, however, was balanced in the two patient groups. Conclusions: The recommended dose of treosulfan for further clinical trials is 3.5 g/m2 in combination with 1g of gemcitabine, based on toxicity and survival data of this study. No significant financial relationships to disclose.
Fluid volume and albumin kinetics occurring with major surgery
Authors: R. C. Hoye
Journal: JAMA (1972)

Studies investigating fluid volume dynamics and albumin kinetics in patients undergoing major abdominal surgery indicate that during the operation, marked deficits develop in the total red blood cell volume, plasma volume, extracellular fluid volume, and the total exchangeable albumin pool. A disproportionate deficit in the plasma volume occurring in the course of the operation is believed to be secondary to a functional extracellular fluid volume deficit and abnormal losses of albumin from the intravascular compartment. Deficits in these compartments occurred during the operation in every patient studied. In some patients the plasma volume deficit immediately postoperatively amounted to close to 50% of the volume present when the patient went into the operating room. In the course of a regional node dissection in nine patients studied, a 29% deficit developed in the total body albumin pool.
Subscapular Swellings
Authors: K. E. McIver
Journal: BMJ (1955)

Background: The molecular links between breast cancer and obesity have been studied for many years. Obesity significantly increases the incidence rate and chance of morbidity of breast cancer. Leptin, mainly secreted by adipocytes, plays an important role in breast cancer development. Leptin expression is up-regulated in obesity and it can promote breast cancer cell growth. Zeranol is used as an anabolic growth promoter to stimulate cattle growth in the U.S. beef industry. (—)-Gossypol, a natural polyphenolic compound extracted from cottonseed, is an anticancer chemopreventive agent. Materials and Methods: Zeranol, leptin and (—)-gossypol were used to investigate MCF-7 Adr cell growth. Results: Leptin enhanced the sensitivity of MCF-7 Adr cells to zeranol and increased cell growth. Exposure to zeranol may lead to initiation of transformation of normal breast cells to breast preneoplastic cells. Conclusion: It is suggested that obese individuals may be at greater risk of developing zeranol-induced breast cancer.
Correction: On Camera
Authors: Jeremy Wight
Journal: BMJ (1991)

But a more robust utilitarian approach might see a bit of bullying as a worthwhile cost for more transplants, as well as saving relatives some agonising decisions.Elizabeth Ward advocated an opting out system such as operates in some European countries.The discussion of this was tantalis- ingly brief-a glimpse of a solution in the last minutes of the programme.How would a dissent register work?How m-any more organs are obtained?How quickly do cultural expectations change to accept the idea that the state has rights over the dead body?Why is it that we ask the state to treat the sick, but deny it the best resources to do so?It is inevitable that a short programme on such a topic should raise more questions than it answers.But at least two (lay) viewers have since ascertained their partners' views on organ donation.
The Breakthrough
Authors: David S. Pisetsky
Journal: Annals of Internal Medicine (1996)

On Being a Doctor1 February 1996The BreakthroughDavid S. Pisetsky, MD, PhDDavid S. Pisetsky, MD, PhDDuke University Medical Center Durham, NC 27705Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-124-3-199602010-00013 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail “Did you hear about the big breakthrough on the news last night?” the patient said in an expectant voice, startling me as I edged past his bed on my morning rounds.I knew the man as Roy Carver, but I had never spoken to him before. He was the roommate of one of my patients, but usually, when I was rounding, Carver would be concealed by a curtain drawn around his bed, either asleep, drugged, or reclusive.I turned toward Carver, who was propped on pillows. He seemed ready to cross the boundary that separates sickness from terminal illness. I ... Author, Article, and Disclosure InformationAuthors: David S. Pisetsky, MD, PhDAffiliations: Duke University Medical Center Durham, NC 27705Corresponding Author: David S. Pisetsky, MD, PhD, Duke University Medical Center, Veterans Affairs Medical Center, Box 151G, Room E-1008, 508 Fulton Street, Durham, NC 27705. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTruth tellingReport of the American Medical Association Council on Ethical and Judicial Affairs: Withholding Information from Patients: Rethinking the Propriety of “Therapeutic Privilege” 1 February 1996Volume 124, Issue 3Page: 345-347KeywordsBreathingCancer treatmentCardiac musclesDeceptionHeartHeart failureMyocardiumNursesT cell receptorsTouch ePublished: 15 August 2000 Issue Published: 1 February 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Editorial: Sleeping sickness.
Journal: BMJ (1974)

participation in the E.E.C. ?The Common Market countries are considering restrictions in the use of antiobitics.Some have already attempted to do so, but without a common policy the movement of foods, animals, and peoples between the various countries will reduce the effectiveness ofthe U.K. precautions.And what of the rest of the world?The W.H.O.information centre will help to collect data, but strong measures are needed until effective means are found to remove R-factors and plas- mids from bacterial cells under natural conditions.In the meanwhile complete agreement should be established that our most powerful drug weapons will be used in their truly cura- tive role to destroy and not to maintain infectious agents causing acute disease.
Essentials of Anatomy
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Visit
Authors: Jane O. Wayne
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Experimental Aluminum Pathology in Rabbits: Effects of Hydrophilic and Lipophilic Compounds
Authors: G. Giorgio Bombi, Benedetto Corain, Mose Favarato, Renzo Giordano, Marino Nicolini, Maurizio Perazzolo, Andrea Tapparo, Paolo Zatta
Journal: Environmental Health Perspectives (1990)

Aluminum lactate [Al(lact)3] (hydrophilic, hydrolytically unstable) and aluminum acetylacetonate [Al(acae)3] (lipophilic, hydrolytically stable) were tested as potential toxicants to rabbits upon IV administration both as aqueous solutions and as liposome suspensions. Both chemicals behaved as cardiotoxic agents when administered as aqueous solutions, but Al(acae)3 was at least two orders of magnitude more active than Al(lact)3. Al(acae)3, but not Al(lact)3, caused myocardial infarcts resembling those in humans (with contraction bands) at doses as low as 0.24 mg/kg body weight, as well as a prominent acanthocytosis. Al(lact)3, when administered as a liposome suspension, was about 300 times more toxic than in aqueous solution, although cardiac damage was not infarctual in character. Both chemical and physical speciation of aluminum(III) thus play an essential role in determining the toxicity of the metal.
A racial difference in incidence of lactase deficiency. A survey of milk intolerance and lactase deficiency in healthy adult males
Authors: T. M. Bayless
Journal: JAMA (1966)

An incidence survey of milk intolerance and lactase deficiency was conducted in 40 healthy nonpatient volunteers. There were 20 Negroes and 20 whites. Nineteen of the 20 Negro subjects and two of the 20 white subjects gave a history of milk intolerance. The majority had noted the onset during or after adolescence. Lactose intolerance occurred in 20 of the 21 milk-intolerant subjects; 18 of the 20 were Negro. There was also a prominent racial difference in the incidence of low levels of intestinal lactase activity. Deficient levels were observed in 70% of the 20 Negroes in contrast to only one of 20 whites. These data strongly favor a genetic etiology for the isolated lactase deficiencies seen so commonly in adults.
Continuing Medical Education
Journal: JAMA (1980)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal