tbuckley/cabot-search huggingface dataset:
Treatment of acute otitis media
Authors: A. J. Saah
Journal: JAMA (1982)

ACUTE otitis media is an episodic disease in which individual occurrences usually resolve without specific treatment. Sequelae of acute or recurrent infection, however, are often serious and include decreased hearing, chronic mastoiditis, meningitis, cholesteatoma, tympanosclerosis, destruction of the ossicular chain, or facial nerve damage. Specific treatment of the disorder is largely aimed at preventing or reducing sequelae or complications, rather than affecting the acute episode itself. In a recent review of two Finnish prospective studies, Quarnberg and Palva<sup>1</sup>state: "Treatment of acute otitis media, which was very straightforward up to the 1950s, has during the era of antibiotics given rise to much controversy. There are advocates of all possible methods, ranging from the use of antibiotics alone and myringotomy alone to both combined. Fortunately, no one proposes no treatment." Now, even that therapeutic nihilism has been broached. Van Buchem et al<sup>2</sup>conducted a double-blind, placebo-controlled, randomized clinical trial,
BBS volume 35 issue 4 Cover and Back matter
Authors: Michael Mccullough, Benjamin Tabak, F Aureli, C Schaffner, D Balliet, T Pronk, P Barclay, S Beckerman, R Crisp, R Meleady, A Dellis, D Spurrett, R Fatfouta, A Jacobs, H Gintis, C Holbrook, Dmt Fessler, M Gervais, J Freyd, J Karremans, R Van Der Wal, V Konecni, S Konrath, I Cheung, D Leiser, M Mccoy, T Shackelford; K O'connor, G Adams, F Pahlavan, M Peterson, D Pietraszewski, M Potegal, S Roberts, J Murray, D Stein, J Van Honk, G Ellis
Journal: Behavioral and Brain Sciences (2012)

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Writing Medicine
Authors: Abraham Verghese
Journal: JAMA (2020)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fulminating Staphylococcic Infections Related with Fucidin and Penicillin or Semisynthetic Penicillin
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Red Tide Toxin, Brevetoxin, Induces Embryo Toxicity and Developmental Abnormalities
Authors: Karen L. Kimm-Brinson, John S. Ramsdell
Journal: Environmental Health Perspectives (2001)

Brevetoxins are lipophilic polyether toxins produced by the red tide dinoflagellate Gymnodinium breve, and their neurotoxic effects on adult animals have been documented. In this study, we characterized adverse developmental effects of brevetoxin-1 (PbTx-1) using an exposure paradigm that parallels the maternal oocyte transfer of toxin. Medaka fish (Oryzias latipes) embryos were exposed to PbTx-1 via microinjection of toxin reconstituted in a triolein oil droplet. Embryos microinjected with doses of 0.1-8.0 ng/egg (ppm) of brevetoxin-1 exhibited pronounced muscular activity (hyperkinesis) after embryonic day 4. Upon hatching, morphologic abnormalities were commonly found in embryos at the following lowest adverse effect levels: 1.0-3.0 ppm, lateral curvature of the spinal column; 3.1-3.4 ppm, herniation of brain meninges through defects in the skull; and 3.4-4.0 ppm, malpositioned eye. Hatching abnormalities were also commonly observed at brevetoxin doses of 2.0 ppm and higher with head-first, as opposed to the normal tail-first, hatching, and doses > 4.1 ng/egg produced embryos that developed but failed to hatch. Given the similarity of developmental processes found between higher and lower vertebrates, teratogenic effects of brevetoxins have the potential to occur among different phylogenetic classes. The observation of developmental abnormalities after PbTx-1 exposure identifies a new spectrum of adverse effects that may be expected to occur following exposure to G. breve red tide events.
Diabetes
Authors: Janet M. Torpy
Journal: JAMA (2009)

Diabetes Diabetes is a common chronic medical condition that leads to increased blood sugar (glucose) levels.Severe complications can come from diabetes, including heart disease, vascular (blood vessel) disease and poor circulation, blindness, kidney failure, poor healing, stroke, and other neurological (nerve) diseases.Diabetes cannot be cured but can be successfully treated.Complications from diabetes can be prevented with careful blood sugar management and control of high blood pressure and high cholesterol levels when present.The April 15, 2009, issue of JAMA is a theme issue devoted to articles about diabetes.
High-frequency ventilation. A new approach to respiratory support
Authors: P. P. O'Rourke
Journal: JAMA (1983)

RESPIRATORY failure from parenchymal lung disease was the admitting diagnosis for 139 of more than 2,200 admissions to the Multidisciplinary Intensive Care Unit at The Children's Hospital Medical Center in Boston during 1982. Despite maximal medical support, 32 of these children died, an unacceptable mortality that demands ongoing investigation of new, innovative, and possibly more effective forms of support. The conventional therapeutic approach to patients with respiratory failure includes safe and effective support of cardiovascular function and gas exchange while treating the underlying pulmonary pathological condition. The present methods of respiratory support include increased ambient oxygen, continuous positive airway pressure, and, ultimately, intermittent positive-pressure breathing. In most patients, gas exchange can be supported by these techniques; but in some situations, ventilationperfusion relationships are so deranged that death results from hypoxemia and/or respiratory acidosis. In addition to clinical limitations, respiratory support can also produce complications. These include oxygen toxicity and barotrauma
Psychoanalysis and the Psychic Disorder of General Paresis.
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A novel mutation of the erythroid‐specific δ‐aminolevulinate synthase gene in a patient with non‐inherited pyridoxine‐responsive sideroblastic anemia
Authors: Hideo Harigae, Kazumichi Furuyama, Kazuko Kudo, Norio Hayashi, Masayuki Yamamoto, Shigeru Sassa, Takeshi Sasaki
Journal: American Journal of Hematology (1999)

A novel missense mutation, G663A, in exon 5 of the erythroid-specific δ-aminolevulinate synthase gene (ALAS2) was identified in a Japanese male with pyridoxine-responsive sideroblastic anemia. Activity of the mutant δ-aminolevulinate synthase protein expressed in vitro was 15.1% compared with the normal control, but was increased up to 34.5% by the addition of pyridoxal 5′-phosphate, consistent with the clinical response of the patient to pyridoxine treatment. The same mutation was also detected in genomic DNA from the oral mucosal membrane of the patient; however, it was not detected in other family members. These findings suggest that this G663A mutation is responsible for sideroblastic anemia in the proband, and may be an index mutation in this pedigree. Am. J. Hematol. 62:112–114, 1999. © 1999 Wiley-Liss, Inc.
Rheumatic
Authors: D. A. Feinfeld
Journal: Annals of Internal Medicine (2005)

Ad Libitum1 February 2005RheumaticD. A. Feinfeld, MDD. A. Feinfeld, MDFrom Eastchester, NY 10709.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-142-3-200502010-00009 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail The serpent-god has cursed her handsto slither sidelong forever, never caress,only to grope past each instant,old loves beyond her painful reach.The hands curl round her walker's handleslike vines struggling up a fence;if tendrils untwist and again run straightthey might reach again for needle and cloth.She moves the cage forward, plantsits four pads the way a cat lands.The floor comes to a fork: she fightsindecision, groans ahead,paths lighted by flickers of painthat harden her limbs to driftwood.Long nails gnarled into unwanted fists,she tries to unclench fingers that bendlike a beam passing through time's glass.D.A. Feinfeld, MDEastchester, NY 10709 Author, Article, and Disclosure InformationAffiliations: From Eastchester, NY 10709.Current Author Address: D.A. Feinfeld, MD, 32 Waterside Close, Eastchester, NY 10709. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 2005Volume 142, Issue 3Page: 186 ePublished: 1 February 2005 Issue Published: 1 February 2005 Copyright & PermissionsCopyright © 2005 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
High-Dose Cyclophosphamide To Treat Severe Aplastic Anemia
Journal: Annals of Internal Medicine (2001)

Summaries for Patients2 October 2001High-Dose Cyclophosphamide To Treat Severe Aplastic AnemiaSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-7-200110020-00002 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Aplastic anemia is a disease of the bone marrow. Bone marrow is the material in the center of bones that produces blood cells. Stem cells are the cells in the bone marrow that become red blood cells (cells that carry oxygen), white blood cells (cells that fight infection), and platelets (cells that help blood to clot). In aplastic anemia, the bone marrow does not produce stem cells, resulting in abnormally low numbers of all blood cells. Aplastic anemia is difficult to treat and can be fatal. The best ... Author, Article, and Disclosure InformationThe summary below is from the full report titled “Durable Treatment-Free Remission after High-Dose Cyclophosphamide Therapy for Previously Untreated Severe Aplastic Anemia.” It is in the 2 October 2001 issue of Annals of Internal Medicine (volume 135, pages 477-483). The authors are RA Brodsky, LL Sensenbrenner, BD Smith, D Dorr, PJ Seaman, SM Lee, JE Karp, I Brodsky, and RJ Jones.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoDurable Treatment-Free Remission after High-Dose Cyclophosphamide Therapy for Previously Untreated Severe Aplastic Anemia Robert A. Brodsky , Lyle L. Sensenbrenner , B. Douglas Smith , Donna Dorr , Phillip J. Seaman , Shing M. Lee , Judith E. Karp , Isadore Brodsky , and Richard J. Jones Metrics 2 October 2001Volume 135, Issue 7Page: I-42KeywordsAplastic anemiaBlood countsBone marrowBone marrow transplantationCellsCyclophosphamidePatientsSafety studiesStem cellsWhite blood cells ePublished: 2 October 2001 Issue Published: 2 October 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Externally Mounted Heart Pump Uses Velour Lining
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Neurometrics
Authors: Marc A. Flitter
Journal: JAMA (1982)

<h3>To the Editor.—</h3> We were pleased to see the discussion of brain electrical activity mapping (BEAM) in the MEDICAL NEWS article "New Diagnostic Technique BEAMed at Dyslexia" (1982;247:2072). We have employed a similar technique at St Francis Hospital, Miami Beach, Fla, for the past two years utilizing spectral analysis of the EEG and auditory and visualevoked test conditions. Our data, as well as similarly collected test results from five other regional centers located in New York, Kansas, Pennsylvania, Maryland, and Illinois, are forwarded to a central computer and support facility in New York. This program, called "Neurometrics," permits each center to have its data analyzed in comparison with a continually updated data base. Computerobtained z scores are used to place a probability value relating regional brain electrical activity to a statistical deviation from the norm. Statistical abnormalities disclosed by these techniques are then compared against reported behavioral consequences of regional
Repository Therapy
Authors: Bernard Dickstein
Journal: JAMA (1964)

<h3>To the Editor:—</h3> Regarding the report in the March 28, 1964, issue (<i>JAMA</i><b>187</b>:1030) by H. B. Appelman, "Untoward Reactions to Emulsion Therapy of Pollenosis," it is important to know who gave the emulsion injection in the two reported cases. How much? With what sterile precautions? How was the emulsion prepared? From 1960 to 1961, there were physicians using large single doses of antigens in emulsions and getting severe reactions. However, in the experience of allergists intensively studying repository injections, the incidence of abscesses and anaphylactic reactions in 1963-1964 is practically nil, in no small part due to smaller doses, multiple injections, and specific techniques.
Selected New Books
Journal: JAMA (1978)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Corrigendum
Journal: British Journal of Dermatology (2020)

In the article by Limandjaja et al 1 , the statistical analysis of the rete ridge formation scores for the normotrophic and hypertrophic scars was incorrect due to a typographical error in the entry of two data points in the normal skin rete ridge scores.See table with raw data below, the maximum score for rete ridge formation is 7, this was inadvertently changed to 8 for 2/5 values in normal skin (see asterisk).
The Fox case
Authors: R. A. McCormick
Journal: JAMA (1980)

MANAGEMENT decisions in medicine, even those involving preservation of life, are profoundly personal. They are like gloves to be fit to a particular hand. For this reason, age-old wisdom has urged that decision making in health care, if it is to remain truly human and in the patient's best interest, should be controlled within the patient-family-physician relationship, always maintaining the right of appeal against potential abuses, of course. Three rather impersonal factors (high technology, cost-containment considerations, and public entities such as the law and the courts) are becoming increasingly influential in medical treatment. Impersonal forces tend to preprogram treatment and are thus a threat to all of us. That is why I see a very ominous drift in the recent New York appellate court resolution of the Fox case. On Oct 2, 1979, Brother Joseph Charles Fox, an 83-year-old member of the Society of Mary, suffered severe cardiorespiratory arrest during
Early lessons
Authors: David Crosby
Journal: BMJ (2004)

hitherto adopted by the courts, which has relied almost exclusively on expert witnesses setting normative boundaries.Because bona fide guidelines carry a presumptive status that means clinicians should generally follow them and if not should take account of them, courts now have available to them the added information and wisdom that guidelines embody.The bottom line so beloved of EBM readers is: guidelines do not actually set legal standards for clinical care but they do provide the courts with a benchmark by which to judge clinical conduct.
Special Institutional Grants for Cancer Cause and Prevention Research Program
Journal: JNCI Journal of the National Cancer Institute (1987)

Special Institutional Grants for Cancer Cause and Prevention Research Program Get access JNCI: Journal of the National Cancer Institute, Volume 78, Issue 6, June 1987, Page 1254, https://doi.org/10.1093/jnci/78.6.1254 Published: 01 June 1987
Hepatic Trauma
Authors: E. Truman Mays
Journal: New England Journal of Medicine (1973)

EXSANGUINATION is the leading cause of death in hepatic trauma. The most recalcitrant source of hemorrhage is arterial. Roentgenographic evaluation of cadaver livers injected with barium before blunt trauma portrays disruption of tertiary branches of the hepatic artery within the depths of the liver. Such vascular lesions are beyond the reach of suturing, and the very multiplicity of arterial defects makes suture repair of individual vessels impractical.The anatomic divisions of the hepatic artery suggest that hemorrhage from a particular lobe can be immediately controlled by ligation of the artery supplying that lobe. In clinical trials this hypothesis is confirmed. . . .
Artificial insemination by donor. Safety and secrecy
Authors: M. E. Guinan
Journal: JAMA (1995)

The report of seven cases of human immunodeficiency virus (HIV) infection in women who were artificially inseminated by donor is another landmark in the history of the HIV epidemic in North America.<sup>1</sup>Details of the investigation reveal that the women had received semen from one of five donors subsequently found to be HIV infected. The women were inseminated at fertility centers between 1981 and 1985, before the first laboratory test for HIV was licensed and available in the United States. The tragedy of these cases is compounded by the fear that more have gone unrecognized. Not all recipients of the semen of the infected donors could be found and 30 recipients refused to be tested. These cases bring the total to 12 known cases of HIV infection in women from artificially inseminated donor semen, four in Australia,<sup>2</sup>two in Canada,<sup>1</sup>and six in the United States.<sup>1,3</sup>