Short-Course Treatment for Latent Tuberculosis Is Associated with More Frequent Liver Injury Than Long-Course Treatment Is
Journal: Annals of Internal Medicine (2002)

Summaries for Patients15 October 2002Short-Course Treatment for Latent Tuberculosis Is Associated with More Frequent Liver Injury Than Long-Course Treatment IsAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-8-200210150-00002 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Tuberculosis is an infection that usually involves the lungs but can also affect other areas of the body. People can develop tuberculosis when exposed to someone with it, especially if the infected person is coughing. People exposed to tuberculosis do not always become sick. The tuberculosis bacteria can "hide out" in a person's body for many years—a situation called latent tuberculosis. Doctors can tell when patients have latent tuberculosis because they have positive tuberculosis skin tests but normal chest x-rays and no symptoms. Because latent tuberculosis can become ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled "Short-Course Rifampin and Pyrazinamide Compared with Isoniazid for Latent Tuberculosis Infection: A Multicenter Clinical Trial." It is in the 15 October 2002 issue of Annals of Internal Medicine (volume 137, pages 640-647). The authors are RM Jasmer, JJ Saukkonen, HM Blumberg, CL Daley, J Bernardo, E Vittinghoff, MD King, LM Kawamura, and PC Hopewell, for the Short-Course Rifampin and Pyrazinamide for Tuberculosis Infection (SCRIPT) Study Investigators.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoShort-Course Rifampin and Pyrazinamide Compared with Isoniazid for Latent Tuberculosis Infection: A Multicenter Clinical Trial Robert M. Jasmer , Jussi J. Saukkonen , Henry M. Blumberg , Charles L. Daley , John Bernardo , Eric Vittinghoff , Mark D. King , L. Masae Kawamura , Philip C. Hopewell , and Metrics Cited byLiver and Pancreatic Injury Induced by Antituberculous Therapy 15 October 2002Volume 137, Issue 8Page: I-32KeywordsClinical trial reportingDrugsHematologic testsIsoniazidLiverLiver function testsSkin testsThoraxTreatment guidelinesTuberculosis ePublished: 15 October 2002 Issue Published: 15 October 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...