tbuckley/cabot-search huggingface dataset:
When the crash cart
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Platelet Aggregation
Authors: James W. Davis
Journal: JAMA (1978)

Using a turbidimetric technique, we determined 1.7 μM adenosine diphosphate—induced platelet aggregation and disaggregation at 37 °C in the platelet-rich plasmas of two groups of men with coronary artery disease. Eleven men were nondiabetic and 11 had adult-onset diabetes mellitus without retinopathy. There were no significant differences (P&gt;.05) between diabetics and nondiabetics of the following variables: age, platelet count in platelet-rich plasma, first and second phases of platelet aggregation, maximum extent of aggregation, and percent disaggregation at three minutes after maximum aggregation occurred. Although the mean adenosine diphosphate—induced platelet aggregation in the platelet-rich plasmas of adult-onset diabetic men with coronary artery disease and no retinopathy was not enhanced, and the mean rate of disaggregation was not reduced, when compared with nondiabetic men with coronary artery disease or with healthy men; a slow rate of platelet disaggregation (less than 10%) occurred more frequently in the platelet-rich plasmas of men with coronary artery disease. (<i>JAMA</i>239:732-734, 1978)
Meetings Calendar
Journal: Circulation Research (2007)

The International Stroke Conference features more than 550 presentations that highlight the most recent advances in the basic sciences of cerebral circulation and brain function, clinical stroke research and outcomes, rehabilitation science, and surgery, as well as exhibitors showcasing the newest advancements in stroke products and services.This conference provides a forum to present recent scientific work related to stroke and cerebrovascular disease.More than 550 posters, oral presentations, and lectures will be featured.See Web site: http://strokeconference.americanheart.org
REGULATION OF THE BILE FLOW
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Reviews
Authors: Jambur Ananth, C.G. Kooiman, Ph. Spinhoven, R.W. Trijsburg, H.G.M. Rooijmans, F. Facchinetti, M. Tarabusi, G. Nappi, Eva Neidhardt, Irmela Florin, Ramiro Verissimo, Rui Mota-Cardoso, Graeme Taylor, Magnus P. Borres, Hidetaka Tanaka, Olav Thulesius, Pier Luigi Rocco, Enrico Barboni, Matteo Balestrieri
Journal: Psychotherapy and Psychosomatics (1998)
Membranes, Receptors, and the Immune Response
Journal: JNCI Journal of the National Cancer Institute (1979)

Membranes, Receptors, and the Immune Response Get access JNCI: Journal of the National Cancer Institute, Volume 63, Issue 1, July 1979, Page 269, https://doi.org/10.1093/jnci/63.1.269 Published: 01 July 1979
The 2014 Hajj and Umrah – current recommendations
Authors: Collective Eurosurveillance editorial team
Journal: Eurosurveillance (2014)

Preview this article: The 2014 Hajj and Umrah – current recommendations, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/19/23/art20826-en-1.gif
Booknotes
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Transactions of the Indiana State Medical Society, Fifty-Second Annual Session held in South Bend, May, 1901.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A High-Yield Sampler for Toxicological Characterization of Complex Mixtures in Combustion Effluents
Authors: Edward L. Kruzel, Arthur L. Lafleur, Andrew G. Braun, John P. Longwell, William G. Thilly, William A. Peters
Journal: Environmental Health Perspectives (1991)

Combustion snmplig for toxicologialsm tien reir s tht large (>110 n) lots ofcompex orgnic mixtures of wide vtlit range be rapidly from high temperate gases without n .A new sampler, meeting these criteria for studies ofpublic beiah itest, has been deeped and d__ a The device p s high s_ng rates and intimate contactfng ofthe sampled stram with large volumes ofa wel-cooled solent, dichkoomehane (DCM).This pomots rapid orpncs dissolution from carier ps and p r and prompt dflution and quenching of the reslting solution, result in high anics coection efficiencies with minimal DCM kse Solent separtion then remits lre quantities ofconcentratedorgnics for chemical analysis and toxicologia testlng One-to seven-hour inrgatons of in-flame, post-lame, and fu gs regions gave 50-to 25mgyeldsofcomple ornic ures.Inside- by-sde samplingofcombustion a ut, theDCM sampler povided igryidofDCM soubls ( ntd wlthcomplex o nic ) andofS S ui} mutgens(activewthotw esogos igagents)thandidafflter/polymeric sobent bed smplngtrain.The new sampler abocolects polar and high volatile such as benzaheyde, pentadiyne, m-andpe-dithynyl-benzene, and 1-hezen-3,5-diyne.N ation of n thalene and pyrene in DCM solution (1 mg/mL each) ws kss than 1 part in 7 aftera345-min eqxsure to a bubblingw of moist N2/air mixture (1:1 v/v) con- ining 107 ppm NO and L5 ppm NO2, i di g that for these ondition aDCM snplershould resist artfact nitration of a s Howver, becase ofthe very high bacteria ofsome Ihd the wide nge ofsampl- ing conditions ofenvimnt interest, nitation and all artfts must stM be scrutnied when usng the DCM sampler.The DCM sampler is expected to contribute to public health impact AstM by facilating deald determinations ofthe identities, compostions, concentrations, sources, formation mechanisms, and biological activity ofenvironmen- tal toxicants in gaseous atmospheres.
Endoscopic ultrasound
Authors: D. Gilbert, I. Penman
Journal: Endoscopy (2008)

Endoscopic ultrasound (EUS) continues to challenge the boundaries of current applications in clinical practice, but as we anticipate new therapeutic roles in linear-array EUS, challenges remain in established diagnostic roles, especially in relation to pancreatic disease. With parallel advances in endoscopic and cross-sectional imaging, re-evaluation of the role of EUS in cancer staging is also necessary. Furthermore, quality and safety issues are increasingly being highlighted. A focused review of the important themes emerging from this year’s DDW meeting is presented here.
BOOK REVIEW
Authors: D. BLUM
Journal: JNCI Journal of the National Cancer Institute (1994)

Journal Article BOOK REVIEW Get access Taking Charge: Overcoming the Challenges of Long-term Illness Irene Pollin , Susan K. Golant . New York : Times Books , 1994 . 262 pp., $20.00. ISBN -0-8129-2258-1 DIANE BLUM, M.S.W. DIANE BLUM, M.S.W. Executive Director Cancer Care Inc.1180 Avenue of the Americas, New York, NY 10036 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 86, Issue 19, 5 October 1994, Page 1479, https://doi.org/10.1093/jnci/86.19.1479 Published: 05 October 1994
Factitious methemoglobinemia
Authors: Karen M. Carr, Laurence Elias, Lee C. Caruana, Ian Rabinowitz
Journal: American Journal of Hematology (1999)

We report the case of a 26 year-old female who was treated on numerous occasions for methemoglobinemia believed secondary to surreptitious abuse of dapsone as part of a factitious disorder. Am. J. Hematol. 62:196–197, 1999. © 1999 Wiley-Liss, Inc.
IS SALICYLIC ACID AS A FOOD PRESERVATIVE HARMFUL?IS SALICYLIC ACID AS A FOOD PRESERVATIVE HARMFUL?
Journal: JAMA (2003)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
German cancer specialist cleared of fraud allegations
Journal: BMJ (2004)

sweating.His wife brought him to the emergency department on three occasions-16, 19, and 23 days after starting diclofenac-and he was noted to be hypoglycaemic with blood glucose concentrations of 1.2-2.5 mmol/l.At each visit his symptoms responded to intravenous glucose and feeding.No investigations were done at his first two visits to the emergency department.At his third visit, his blood glucose concentration was 1.2 mmol/l.A history taken at this visit after correction of hypoglycaemia was unremarkable.The patient reported no decrease in his appetite or increase in physical activity in the past month and no decrease in urine output.Physical examination was unremarkable, with a blood pressure of 150/90 mm Hg.There was no peripheral oedema.Investigations showed a raised serum creatinine concentration of 440 mol/l and a raised serum urea concentration of 14.6 mmol/l (1.7-8.3 mmol/l); serum potassium concentration was 4.8 mmol/l (3.5-5.0 mmol/l).Since starting to take the non-steroidal antiinflammatory drug diclofenac, the patient had developed a decline in renal function with a fourfold increase in serum creatinine.Diclofenac was immediately stopped and his insulin dosage was decreased.Two weeks later, his serum creatinine concentration returned to baseline and he resumed his usual insulin dosage, with no further episodes of hypoglycaemia and with reasonable glucose control.
Abstract P258: Alterations in DNA Methylation of Circadian-related Genes are Associated with Metabolic Traits: A Gene-set Analysis in Monozygotic Twins
Authors: Qiang AN, Yun Zhu, Jack Goldberg, Viola Vaccarino, Jinying Zhao
Journal: Circulation (2016)

Background: Circadian disruption adversely affects the metabolic system and increases the risk of metabolic disorders. Epigenetic factors, especially DNA methylation, are essential for the regulation of both circadian clock and metabolic function, but whether and how altered DNA methylation of circadian-related genes affects metabolic traits is poorly understood. Moreover, previous DNA methylation analysis largely focused on individual CpG sites in single genes, but the joint contribution of methylation variation at multiple CpG sites in multiple genes may explain a larger proportion of disease variability compared to single-CpG single-gene analysis. Objective: To assess the joint contribution of 84 CpG sites in six circadian-related genes to interindividual variability in metabolic traits in a well-matched monozygotic (MZ) twin sample. Methods: We analyzed 69 apparently healthy, male-male MZ twin pairs recruited by the Emory Twins Heart Study. All twins were middle-aged (mean age 55) veterans from the Vietnam Era Twin Registry, and were free of self-reported histories of CVD and diabetes at the time of enrollment. Peripheral blood DNA methylation at 84 CpG sites in the promoter regions of six circadian-related genes, including ARNTL, CLOCK, MC4R, PER1, PER2, and PER3, were quantified by bisulfite pyrosequencing. We first examined the association of DNA methylation at individual CpG site in each candidate gene with metabolic phenotypes (waist circumference, systolic blood pressure, HbA1c, HOMA-IR, HDL, LDL, and hsCRP) by regressing the intra-pair difference in each trait on the intra-pair difference in DNA methylation at each CpG site, adjusting for twin age and intra-pair differences in smoking (pack-year), alcohol consumption (g/day), level of physical activity and Beck depression scale. We then conducted promoter-based association analysis by combining P-values of all CpG sites within a gene based on single CpG analysis using a weighted truncated product method (TPM) with regression coefficient as weight. Gene-set analysis was performed by combining P-values of all six genes using TPM. Multiple testing was controlled by false discovery rate. Results: Individual CpG site analysis showed that, although methylation variation at multiple CpG sites in multiple genes was marginally associated with one or more metabolic traits, only a few sites survived multiple testing. Gene-set analysis, however, revealed that methylation variation in all six circadian-related genes was significantly associated with all studied metabolic traits (all P’s≤0.0009). Conclusion: DNA methylation variation in circadian-related genes jointly contributes to metabolic function, independent of genes and early family environment. These findings may shed light on the role of DNA methylation in the circadian control of metabolic functions.
Acute Cholecystitis
Authors: Seymour I. Schwartz
Journal: JAMA (1972)

This monograph, which considers acute cholecystitis from all aspects, is unusual in that it is a text concerned with a single disease. It is quite panoramic in its approach, beginning with interesting historical vignettes and offering pertinent experimental data along with well-synthesized concepts. The lucid presentation of experiments in pathophysiology represents a major strength of the book. Clinical and roentgenographic diagnoses are both considered in detail. Cholangiography and the author's particular interest in cholangiomanometry are placed in proper perspective. Further, Dr. Schein is pleasantly nonpontifical in his recommendations for medical management. His discussion of operative technique is somewhat overly specific but quite complete in considering a variety of circumstances which the surgeon may encounter. The section titled "Special Problems" is especially interesting, and acute cholecystitis in the diabetic, one of the author's interests, is emphasized, as is the section on antibiotics and biliary infection. The 629 references attest to the
A recurrent laminin 5 mutation in British patients with lethal (Herlitz) junctional epidermolysis bullosa: evidence for a mutational hotspot rather than propagation of an ancestral allele
Authors: G.H.S. ASHTON, J.E. MELLERIO, M.G.S. DUNNILL, L. PULKKINEN, A.M. CHRISTIANO, J. UITTO, R.A.J. EADY, J.A. McGRATH
Journal: British Journal of Dermatology (1997)
"World Class" Physicians Get First US-Israeli Training
Authors: M. Mitka
Journal: JAMA (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Results and Benefits of a Maternal Serum α-Fetoprotein Screening Program-Reply
Authors: Elliot Alpert
Journal: JAMA (1985)

<h3>In Reply.—</h3> Dr Macri in his comments on and questions about our article has failed to recognize the difference between a screening program (based largely on private obstetric practice) and an epidemiologic study. Our results directly reflect experience in a well-established clinical screening program over more than eight years. In an epidemiologic project, great effort would have to be made to avoid selection or recruitment bias in the study of a routine pregnancy population, with specific strict adherence to include or account for all such patients. Obviously in a clinical setting and during an extended period when MSAFP was being used selectively by some obstetricians, usual projected statistical expectations would not apply. Because of our long record and local and national use as a reference laboratory, some skewing of the pregnancy population we studied would clearly occur. A suspicious history, suspected deviation from normal fetal development, and abnormality suspected by
Book Review Essentials of Fevers . Gerald E. Breen, M.D., Ch.B. (N.U.I. Dub.), D.P.H., D.O.M.S. (R.C.P.Lond., R.C.S.Eng.). 12°, cloth, 273 pp., with 24 illustrations. Baltimore: Williams &amp; Wilkins Co., 1939. $3.00.
Journal: New England Journal of Medicine (1940)
Maternal Drug Abuse and Human Term Placental Xenobiotic and Steroid Metabolizing Enzymes in Vitro
Authors: Pauliina Paakki, Helene Stockmann, Marjatta Kantola, Peruka Wagner, Urs Lauper, Renate Huch, Eivor Elovaara, Pertti Kirkinen, Markku Pasanen
Journal: Environmental Health Perspectives (2000)

We evaluated the impact of maternal drug abuse at term on human placental cytochrome P450 (CYP)-mediated (Phase I) xenobiotic and steroid-metabolizing activities [aromatase, 7-ethoxyresorufin O-deethylase (EROD), 7-ethoxycoumarin O-deethylase (ECOD), pyrene 1-hydroxylase (P1OH), and testosterone hydroxylase], and androstenedione-forming isomerase, NADPH quinone oxidoreductase (Phase II), UDP-glucuronosyltransferase (UGT), and glutathione S-transferase (GST) activities in vitro. Overall, the formation of androstenedione, P1OH, and testosterone hydroxylase was statistically significant between control and drug-abusing subjects; we observed no significant differences in any other of the phase I and II activities. In placentas from drug-abusing mothers, we found significant correlations between ECOD and P1OH activities (p < 0. 001), but not between ECOD and aromatase or P1OH and EROD activities; we also found significant correlations between blood cotinine and UGT activities (p < 0.01). In contrast, in controls (mothers who did not abuse drugs but did smoke cigarettes), the P1OH activity correlated with ECOD, EROD (p < 0.001), and testosterone hydroxylase (p < 0.001) activities. Our results (wider variation in ECOD activity among tissue from drug-abusing mothers and the significant correlation between P1OH and ECOD activities, but not with aromatase or EROD activities) indicate that maternal drug abuse results in an additive effect in enhancing placental xenobiotic metabolizing enzymes when the mother also smokes cigarettes; this may be due to enhancing a "silent" CYP form, or a new placental CYP form may be activated. The change in the steroid metabolism profile in vitro suggests that maternal drug abuse may alter normal hormonal homeostasis during pregnancy.