Itraconazole and Amphotericin B To Treat Fungal Infections in Patients with Cancer Who Are Receiving Chemotherapy
Journal: Annals of Internal Medicine (2001)

Summaries for Patients18 September 2001Itraconazole and Amphotericin B To Treat Fungal Infections in Patients with Cancer Who Are Receiving ChemotherapySearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-6-200109180-00005 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?When patients with cancer receive chemotherapy (drugs used to kill cancer cells), normal cells in the bone marrow are often temporarily damaged or destroyed. Since the bone marrow produces cells that fight infection (white blood cells, or leukocytes), chemotherapy often increases susceptibility to infection. These infections are usually due to bacteria or fungi. It is often difficult to determine which organism has caused infection. Fungi are difficult to treat and often cause fatal complications, unless treatment is started early or before infection starts. Patients with low white blood ... Author, Article, and Disclosure InformationThe summary below is from the full report titled “Intravenous and Oral Itraconazole versus Intravenous Amphotericin B Deoxycholate as Empirical Antifungal Therapy for Persistent Fever in Neutropenic Patients with Cancer Who Are Receiving Broad-Spectrum Antibacterial Therapy. A Randomized, Controlled Trial.” It is in the 18 September 2001 issue of Annals of Internal Medicine (volume 135, pages 412-422). The authors are M Boogaerts, DJ Winston, EJ Bow, G Garber, AC Reboli, AP Schwarer, N Novitzky, A Boehme, E Chwetzoff, K De Beule, and the Itraconazole Neutropenia Study Group.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoIntravenous and Oral Itraconazole versus Intravenous Amphotericin B Deoxycholate as Empirical Antifungal Therapy for Persistent Fever in Neutropenic Patients with Cancer Who Are Receiving Broad-Spectrum Antibacterial Therapy Marc Boogaerts , Drew J. Winston , Eric J. Bow , Gary Garber , Annette C. Reboli , Anthony P. Schwarer , Nicolas Novitzky , Angelika Boehme , Elisabeth Chwetzoff , and Karel De Beule , and the Itraconazole Neutropenia Study Group* Metrics 18 September 2001Volume 135, Issue 6Page: I-39KeywordsAmphotericinAntifungalsBlood countsCancer chemotherapyCellsChemotherapyDrugsFeversHyperthermiaWhite blood cells ePublished: 18 September 2001 Issue Published: 18 September 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...