tbuckley/cabot-search huggingface dataset:
"CARDIOLOGY AND THE GENERAL PRACTITIONER"
Journal: JAMA (1922)

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Surveillance for Epidemics—United States
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Revision of the Code.
Authors: None Inquirer
Journal: JAMA (1893)

<h3>To the Editor of The Journal of the American Medical Association.</h3><h3>Sir:</h3> —The discussion of the Code is assuming much importance inThe Journal, but not too much considering the issues involved. I have followed it with great interest as the different writers very distinctly indicate the cleavages of professional opinion on great ethical subjects. They vary from a keen appreciation of, and devotion to the great moral truths and principles which underlie nobility of character in any profession or business, as set forth in the classical letters of "Conservative Member," to the utter lack of all pretensions to professional honesty as exhibited in the letters of "Fair Play," and "Practitioner." This discussion has not only convinced me that the Code as it stands should be firmly maintained by the Association, but that the schools should be compelled to teach it thoroughly to every graduate. It seems impossible that some
Screening Mammography: A Missed Clinical Opportunity?
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MEDICAL JOURNALS.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DOUKHOBOR FANATICISM.
Journal: JAMA (1902)

A curious story comes from Assiniboia in the Canadian northwest. A few years ago a considerable number of Russian quakers, or doukhobors as they are called, settled there and have thus far prospered. Prosperity, however, seems to have been too much and too sudden for them, after their Russian persecutions; they are, as a Canadian correspondent puts it, ill at ease without trouble of some sort. Therefore, under the influence of a newly arrived Russian prophet, and some say from that of Tolstoi's works, a considerable number of doukhobors have arrived at the conclusion that it is wrong not only to deprive any animals of their life or freedom, but also to appropriate to their own use their services and products. They accordingly have turned their animals loose, commending them to Providence, and made bonfires of their woolen clothing, leather shoes and whatever else they had about them that was
Untersuchungen über die Körperlichen Störungen bei Geisteskranken.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 3410: FAK is Required for Neural Crest Cell Remodeling of the Cardiac Outflow Tract
Authors: Ainara Vallejo-Illarramendi, Louis F Reichardt
Journal: Circulation (2008)

Background: Cardiac neural crest cells (NCCs) participate in the remodeling of the outflow tract and pharyngeal arch arteries during cardiovascular development. Abnormal growth factor and integrin signaling in cardiac NCCs leads to cardiovascular malformations. Focal adhesion kinase (FAK) is a ubiquitous protein kinase that transduces integrin and growth factor signaling pathways. However, a direct role for FAK in cardiac NCC morphogenesis has not been demonstrated. Here we have used a Cre/loxP method for NCC-specific deletion of FAK in mouse embryos. Results: We found that targeted deletion of FAK in NCC results in craniofacial and cardiovascular malformations, leading to early postnatal lethality. Mutant mice display cleft palate together with several cardiovascular defects, including persistent truncus arteriosus, transposition of the great arteries, overriding aorta, ventricular septal defect and type B interruption of the aortic arch, all of which resemble common forms of human congenital heart disease. We found that NCC counts in the outflow tract of FAK mutant and control littermates are similar at E11, suggesting that FAK is not required for cardiac NCC migration to the outflow tract. Furthermore, NCCs appear to differentiate normally into smooth muscle cells in the outflow tract of FAK conditional mutant embryos at E11 and E12.5. In contrast, NCCs in the aortic arch arteries of FAK conditional mutants show impaired differentiation into smooth muscle cells in these embryonic stages. Additionally, we observed that rotation of the outflow tract fails to occur by E11 in FAK mutants, resulting in a dextroposed aortic root. Moreover, FAK-deficient NCCs form a less compact mesenchyme in the conotruncal cushions and show disorganized F-actin stress fibers in the aorticopulmonary septum. Conclusions: Our results indicate that FAK plays an essential role in the development of the cardiac outflow tract and in the remodeling of aortic arch arteries. However, it is dispensable for migration and differentiation of cardiac NCC in the outflow tract. Further studies with this novel model of congenital heart disease may help elucidate the NCC signaling pathways that orchestrate septation of the outflow tract.
A FACTOR IN PROSECUTIONS FOR THE PRODUCTION OF ABORTION.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Particle concentrations in urban microenvironments.
Authors: J I Levy, E A Houseman, L Ryan, D Richardson, J D Spengler
Journal: Environmental Health Perspectives (2000)

Although ambient particulate matter has been associated with a range of health outcomes, the health risks for individuals depend in part on their daily activities. Information about particle mass concentrations and size distributions in indoor and outdoor microenvironments can help identify high-risk individuals and the significant contributors to personal exposure. To address these issues in an urban setting, we measured particle count concentrations in four size ranges and particulate matter (3/4) 10 microm (PM(10)) concentrations outdoors and in seven indoor microenvironments in Boston, Massachusetts. Particle counts and PM(10) concentrations were continuously measured with two light-scattering devices. Because of the autocorrelation between sequential measurements, we used linear mixed effects models with an AR-1 autoregressive correlation structure to evaluate whether differences between microenvironments were statistically significant. In general, larger particles were elevated in the vicinity of significant human activity, and smaller particles were elevated in the vicinity of combustion sources, with indoor PM(10) concentrations significantly higher than the outdoors on buses and trolleys. Statistical models demonstrated significant variability among some indoor microenvironments, with greater variability for smaller particles. These findings imply that personal exposures can depend on activity patterns and that microenvironmental concentration information can improve the accuracy of personal exposure estimation.
Selective decontamination of the gut.
Authors: S W Atkinson, D J Bihari
Journal: BMJ (1993)

animal models of pain.Nor do we know how long afferent blockade must be continued during and after surgery to ensure that neuronal plasticity is prevented and not simply delayed.These considerations are important now that modem clinical anaesthesia uses low concentrations of volatile anaesthetics which abolish consciousness but may still allow sensitisation of the cord unless nociceptive input is otherwise reduced-a concern voiced 80 years ago by Crile.'6Perhaps general anaesthesia should be combined with pre-emptive local and regional anaesthetic blocks more often.As is so often the case, more work needs to be done.Some encouraging laboratory and clinical studies suggest that preemptive analgesia does reduce pain after surgery, but the optimum choices of agents and timing required for a clinically useful effect remain to be established.The underlying mechanisms may also be relevant to some chronic neuropathic pain states.
LIFE ON A SPACE SHIP
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Anthropometric, body composition and somatotype differences of Iranian elite female basketball and handball players
Authors: M Gholami, L Sabbaghian Rad
Journal: British Journal of Sports Medicine (2010)

The aims of the this study were: (A) to determine the anthropometric profile, body composition and somatotype of female basketball (B), and handball (H) players, (B) to compare the mean scores among H and B and (C) to detect possible differences in relation to competition level. A total of 28 female athletes (B=15, H=13), all members of the Iranian national teams, participated in this study. Anthropometric measures required for the calculation of body composition indexes and somatotype components were obtained according to the established literature. These measurements were height, weight, triceps, subscapular, suprailiac, thigh and calf skinfolds, bi-epicondylar diameter of femur and humerus, and flexed biceps and calf girths. All skinfold measurements were taken on the right side of the body with the Yagamy skinfold caliper. Measurements were taken during the peak of the competition season. Subjects' somatotypes were determined by using the Heath-Carter anthropometric method. Somatotype was calculated using the Heath-Carter method.1 Data were analysed using t test with significance accepted at p&lt;0.05. There was no significant difference of body mass index, waist-to-hip ratio, fat weight, fat per cent, fat-free weight, waist to hip ratio and stature, weight and triceps skinfold thickness among B and H group. Although B and H group had homogeneity in somatotype characteristics (p&lt;0.05). There was a difference somatotype characteristics among B and H group (p&lt;0.001). Somatotype characterised as mesoendomorph in B group (3.6, 3.5, 2.4) and H athletes' somatotype was mesoendomorph (3.6, 4.7, 1.7). Anthropometric and body composition variables of elite female basketball and handball players were same, but they had different somatotype characteristics. Selection criteria, hours of training and sport-specific physiological demands during the game could explain the observed differences.
AMA-RPS Organizational Development for 1992—The Communication Network
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Corrigendum to “Adenoviral Delivery of Tumor Necrosis Factor-α and Interleukin-2 Enables Successful Adoptive Cell Therapy of Immunosuppressive Melanoma”
Authors: Mikko Siurala, Riikka Havunen, Dipongkor Saha, Dave Lumen, Anu J. Airaksinen, Siri Tähtinen, Víctor Cervera-Carrascon, Simona Bramante, Suvi Parviainen, Markus Vähä-Koskela, Anna Kanerva, Akseli Hemminki
Journal: Molecular Therapy (2016)

Molecular Therapy (2016) 24: 1435–1443. doi:10.1038/mt.2016.134 Following publication, it was noted that the y-axis in Figure 5b was mislabeled as “CD8+CD3+ expressing PD-L1.” The correct label is “CD8+CD3+ expressing PD1.”
67TiP HER2CLIMB-02: A randomized, double-blind, phase III study of tucatinib or placebo with T-DM1 for unresectable locally-advanced or metastatic HER2+ breast cancer
Authors: N. Masuda, S. Hurvitz, L. Vahdat, N. Harbeck, A.C. Wolff, S.M. Tolaney, S. Loi, J. O'Shaughnessy, D. Xie, L. Walker, E. Rustia, V.F. Borges
Journal: Annals of Oncology (2020)
Health care quality and cost effectiveness
Authors: Raymond Chung, Wenyu Lin, Chuanlong Zhu, Jian Hong, Lei Zhao, Qikai Xu, Pattranuch Chusri, Nikolaus Jilg, Dahlene Fusco, Esperance Schaefer, Cynthia Brisac, Lee Peng, Abbas Mourad, Michael Schwarzinger, Nathalie Ganne-Car- Rie, Isabelle Rosa, Philippe Mathurin, Sylvie Deuffic-Burban
Journal: Hepatology (2013)

mRNA levels and RNA variants, together with HCV replication were monitored by qPCR and RT-PCR in HCV JFH1 and OR6 replicon cells.Results: We identified 26095 genes from RNA-Seq transcription level splicing analysis.There were 419 genes with more than 2 fold difference between Neg siRNA and SART1 siRNA whether in the presence or absence of IFN.Ingenuity Pathway Analysis (IPA) identified at least 10 functional pathways, including cell signaling, interferon and antiviral response pathways.Our qPCR data confirmed consistency between RNA-Seq and qPCR analysis.We found that siRNA to SART1 reduced classical ISG mRNA transcription expression including Mx1, IFIH1 (MDA5), OAS3, and DDX58 (RIG-I).However, we found that SART1 did not affect Jak-STAT pathway genes including IFNAR1, STAT1, JAK1, IRF1, and IRF9 mRNA transcription expression.Our bioinformatics alternative exon splicing analysis identified 1589 down-regulated and 1155 up-regulated genes and exons by SART1 or IFNα treatments.Our RT-PCR images have confirmed alternative mRNA splicing for several genes, including NOMO3, EIF4G3, MICU1, GORASP2, XPO1, ZFAND6, and RAB6A.We found that siRNA or overexpression of EIF4G3, GORASP2, or ZFAND6 regulated HCV replication.Conclusions: The spliceosome factor SART1 is not IFN-inducible but is an IFN effector gene.SART1 exerts its anti-HCV action through direct transcriptional downregulation for some ISGs (e.g., IFIH1) and alternative splicing for others, including EIF4G3, GORASP2, and ZFAND6.SART1 does not have effects on IFN receptor or signal transduction components.Taken together, these data imply that SART1 regulates ISGs in a non-classical manner.
TAINTED MONEY.
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal