tbuckley/cabot-search huggingface dataset:
The Library Catalogue and Index. Published by Shepherd &amp; Johnson, Chicago.
Journal: JAMA (1885)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
GONORRHEAL ARTHRITIS.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Wrong ms
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Motility studies in diverticular disease of the colon: Part II Effect of colonic and rectal distension
Journal: Gut (1969)

tients by the open-ended tube method reflects more the narrowed segment from which recording is made rather than any absolute increase in wall activity.It is possible that the exaggerated activity recorded by Painter and Truelove (1964) in patients with diverticular disease stimulated by morphia or prostigmine could be explained on the same basis.The higher intraluminal pressures occurring in the diverticular patients may contribute to the production of pulsion diverticula but the presznt findings would indicate that these pressures develop in a previously narrowed segment of bowel.Whether this narrowing exists before the diverticula appear cannot be deter- mined on the evidence of this study.However, many cases are on record of diverticular disease with narrowing but no diverticula (Morson, 1963;Parks, 1966;Williams, 1967) so it seems possible that the muscular contracture is the primary lesion. SUMMARYThe overall activity recorded using miniature balloons was similar in diverticular disease and in health under basal conditions and after the physiological stimulus of eating.The duration of activity was less but the amplitude of the waves was greater in diseased subjects.Open-ended tubes detected more basal and post- prandial activity in diverticular disease than normal, but this does not necessarily indicate true muscular hyperactivity.Intraluminal pressures are determined not only by wall movements, but the ease with which pressure segments are formed, and this implicates factors such as the diameter of the lumen, mucosal exuberance, and the nature of the bowel content.
Reply to Francesco Montorsi, Paolo Capogrosso, Andrea Salonia’s Letter to the Editor re: Vincent Misrai, Enrique Rijo, Kevin C. Zorn, Nicolas Barry-Delongchamps, Aurélien Descazeaud. Waterjet Ablation Therapy for Treating Benign Prostatic Obstruction in Patients with Small- to Medium-size Glands: 12-month Results of the First French Aquablation Clinical Registry. Eur Urol 2019;76:667–75. Surgery for Benign Prostatic Enlargement: Water Keeps Flowing Under the Bridge but Are Things Changing?
Authors: Vincent Misrai, Enrique Rijo, Kevin C. Zorn, Nicolas Barry-Delongchamps, Aurélien Descazeaud
Journal: European Urology (2019)
Abstract 1113: Targeting PRPK function blocks colon cancer metastasis
Authors: Tatyana Zykova, Ke Yao, Seung Ho Shin, Eunmiri Roh, Weiya Ma, Ann M. Bode, Zigang Dong
Journal: Cancer Research (2019)

Abstract The biological functions of the p53-related protein kinase (PRPK) remain unclear. We have previously demonstrated that PRPK is phosphorylated by the T-LAK cell-originated protein kinase (TOPK) and that phosphorylated PRPK (p-PRPK) promotes colon cancer metastasis. Here, we analyzed colon adenocarcinomas from 87 patients and found that higher expression levels of p-PRPK were associated with later stages of metastatic dissemination (stage III and IV) as compared with earlier stages (stages I and II). Indeed, levels of p-PRPK were higher in metastatic versus malignant human colon adenocarcinomas. Knocking down PRPK expression attenuated colorectal liver and lung metastasis of colon cancer cells in vivo. An in vitro kinase assay indicated that active PRPK does not phosphorylate p53 directly. We found that PRPK phosphorylates survivin, a regulator of colon cancer metastasis. PRPK phosphorylates survivin at Thr34, which is important for survivin stability. Taken together, our data strongly suggest that the PRPK signaling pathway promotes colon cancer metastasis by modulating survivin stability, and that PRPK could be a new prognostic marker for the survival of colon cancer patients. In addition, we identified an FDA-approved bacteriostatic antibiotic, fusidic acid sodium salt (fusidic acid or FA) as an inhibitor of PRPK, and show that FA combined with 5-fluorouracil (5-FU) inhibited PRPK activity and colon cancer metastasis to the lung in mice. We contend that the combination of FA with 5-FU could be an alternative therapeutic strategy to traditional chemotherapy for colon cancer patients with poor prognosis. Citation Format: Tatyana Zykova, Ke Yao, Seung Ho Shin, Eunmiri Roh, Weiya Ma, Ann M. Bode, Zigang Dong. Targeting PRPK function blocks colon cancer metastasis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1113.
Oral contraceptives. Renin, aldosterone, and high blood pressure
Authors: J. H. Laragh
Journal: JAMA (1967)

A relationship was established between the institution of oral contraceptive therapy and the development or enhancement of high blood pressure in eight of 11 patients. In six of eight patients who stopped taking medication, marked improvement or complete correction of hypertension occurred. In two patients, with a second trial of treatment, hypertension again appeared and disappeared. Oral contraceptive therapy produced impressive abnormalities in renin-substrate concentration and in its reactivity to exogenous renin as well as in endogenous renin activity and aldosterone excretion. The relevance of these abnormalities to the development of hypertension is not clear because similar effects occur in treated normotensive women. Further study of a possible connection between excesses of estrogenic and progestogenic substances, renin, aldosterone, and hypertension seems warranted.
PHILIP SYNG PHYSICK (1768-1837)—SURGICAL ARTISAN
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phenytoin Toxicity
Authors: REIN TIDEIKSAAR
Journal: Annals of Internal Medicine (1979)

Letters and Corrections1 April 1979Phenytoin ToxicityREIN TIDEIKSAAR, R.P.A.-C.REIN TIDEIKSAAR, R.P.A.-C.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-90-4-723_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: As evidenced by recent articles published in Annals of Internal Medicine (1) and elsewhere (2), phenytoin is being used more as a therapeutic drug in nonepileptic clinical situations. There is thus an increased likelihood that the primary clinician will encounter patients with phenytoin toxicity who present with subtle symptoms causing possible diagnostic problems.Evidence shows that phenytoin can produce subtle changes in the intellectual and personality functioning of patients even before a full-blown toxic state exists (3). In the presence of the classic motor signs of phenytoin toxicity—hystagmus, ataxia, and dysarthria—the cause of the behavioral disturbances associated...References1. TANAYISRAELPERESECENSCHIABRAMOVAVIRAM AYGAA: Long-term treatment of the syndrome of inappropriate antidiuretic hormone secretion with phenytoin. Ann Intern Med 90:50-52, 1979 LinkGoogle Scholar2. TINDALLWILLERSON RJ: Subacute phenytoin intoxication syndrome. Arch Intern Med 138.1168-1169, 1978 CrossrefMedlineGoogle Scholar3. GLAZER G: Diphenylhydantoin toxicity, in Antiepileptic Drugs, edited by WOODBURY DM, PENRY JK, SCHMIDT RP. New York, Raven Press, 1972, p. 219 Google Scholar4. DODRILL C: Diphenylhydantoin serum levels, toxicity, and neuropsychological performance in patients with epilepsy. Epilepsia 16:593-600, 1975 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: 250 W. Merrick Road, Apt. 1-T; Freeport, NY 11520 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByHypothermia and Phenytoin Toxicity: A Case ReportClinical Features and Management of Poisoning Due to PhenytoinCutaneous and immunologic reactions to phenytoin 1 April 1979Volume 90, Issue 4Page: 723-724KeywordsAdverse reactionsAtaxiaDrug therapyToxicity Issue Published: 1 April 1979 PDF DownloadLoading ...
Acquired Immunodeficency Syndrome Map
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A note from the editors: impact of anthropogenic changes to water on human pathogens
Journal: Eurosurveillance (2016)

Preview this article: A note from the editors: impact of anthropogenic changes to water on human pathogens, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/21/15/eurosurv-21-30200-1-1.gif
THE ACCELERATED MEDICAL CURRICULUM
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
治疗丝聚蛋白相关湿疹和哮喘的药物成本增加
Authors: P. Soares, K. Fidler, J. Felton, R. Tavendale, A. Hövels, S.A. Bremner, C.N.A. Palmer, S. Mukhopadhyay
Journal: British Journal of Dermatology (2018)

湿疹和哮喘是常见的慢性疾病。15‐20%的学龄儿童以及2‐10%的成人受湿疹困扰,而16‐18%的英国人受哮喘困扰。近四分之三患有早发性湿疹(一种严重且持续的湿疹)的儿童将在日后发展为哮喘。丝聚蛋白基因可帮助生成一种蛋白质,在皮肤上形成一道防护屏障,抵御引发过敏的外来物侵入。大约十分之一的人群出现丝聚蛋白基因变化,这会导致其生成缺陷蛋白,不再能够帮助维持此皮肤屏障。本项研究在英国开展,旨在发现丝聚蛋白突变是否关系到治疗湿疹和哮喘的药物处方增加和/或哮喘急性加重(即恶化)次数增加,从而是否会带来各种医疗成本。研究表明,出现此基因变化的湿疹和哮喘儿童患者在大多数童年时期对湿疹和哮喘药物的需求都会大幅增加。出现基因变化的哮喘儿童患者在九年期间还更容易出现哮喘发作,导致疾病的住院治疗和人力成本都相应增加。由此得出结论,只需在一生当中的任何时间(包括出生时或幼儿期)进行简单的“唾液”基因检测,便能够帮助预测湿疹和哮喘等常见慢性病患者的长期医疗成本以及患上更严重疾病的长期风险。出现丝聚蛋白基因突变的儿童和成人可能从具有针对性的治疗方案(比如从出生开始日常使用润肤剂)中受益,为医疗保健系统节省成本并改善疾病控制和生活质量。
Renal transplantation in a Community Hospital
Authors: A. L. Sellers
Journal: JAMA (1976)

Eighty renal transplantations were performed at an urban community hospital over a ten-year period. Forty-two transplants were from living related donors and 38 from cadaver donors. The one-year rejection rate for cadaveric transplants was 35% and for transplants between parents and children, 31%, whereas only one of 21 (5%) transplants between siblings was rejected during the first year. These results compare favorably with those reported by others and appear to justify performance of kidney transplantation in the community hospital setting where large numbers of transplant surgeons and nephrologists are involved, and where the number of transplants never has exceeded 15 per year. (<i>JAMA</i>236:2866-2869, 1976)
CAMP-FOLLOWERS OF SCIENCE.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Contents
Authors: R Moreau, R Bataller, T Berg, J Zucman-Rossi, R Jalan, F Tacke, Samuel Didier, Mondelli Mario, Anna Lok, M Ghany, C Hezode, N Reau, E Svarovskaia, B Doehle, R Shanmugam, H Dvory-Sobol, C Hedskog, J Mcnally, A Osinusi, D Brainard, H Miller, S Mo, J Roberts, S O'leary, S Shafran, J So, C Millbourn, K Bu ¨sch, J Ko, R Schvarcz, K Lindahl, A Bruchfeld, J Ampuero, C Jimeno, R Quiles, J Rosales, S Llerena, N Palomo, P Cordero, F Serrano, J Urquijo, J Moreno-Planas, G Ontanilla, M Herna ´ndez, A Ortega-Alonso, M Maraver, M Bonacci, A Rojas, B Figueruela, X Forns, R Andrade, J Calleja, M Diago, I Carmona, M De La Mata, M Buti, J Crespo, J Pascasio, J Navarro, J Salmero, M Romero-Go ´mez, L Turco, G Garcia-Tsao, I Magnani, M Bianchini, M Costetti, C Caporali, S Colopi, E Simonini, N De Maria, F Banchelli, R Rossi, E Villa, F Schepis, C Wardell, M Fujita, T Yamada, M Simbolo, M Fassan, R Karlic, P Polak, J Kim, Y Hatanaka, K Maejima, R Lawlor, Y Nakanishi, T Mitsuhashi, A Fujimoto, M Furuta, A Ruzzenente, S Conci, A Oosawa, A Sasaki-Oku, K Nakano, H Tanaka, Y Yamamoto, K Michiaki, Y Kawakami, H Aikata, M Ueno, S Hayami, K Gotoh, S.-I Ariizumi, M Yamamoto, H Yamaue, K Chayama, S Miyano, G Getz, A Scarpa, S Hirano, T Nakamura, H Nakagawa
Journal: Journal of Hepatology (2018)
Clinical decision making: from theory to practice. Three battles to watch in the 1990s
Authors: D. M. Eddy
Journal: JAMA (1993)

HOWEVER the debate on national health care reform comes out, and whatever strategies are eventually used to achieve the seemingly incompatible goals of providing universal access, improving quality, and controlling costs, one thing is certain: The day-to-day decisions of those who actually provide health care will be put under ever-increasing stress. Reform will not solve the problems that have been causing the pressure on physician decision making over the last decade; it will rely on further pressure to solve the problems. We know this will occur for several reasons. Begin with the fact that of the three main goals of health care reform— access, quality, and cost—the driving force is cost. To be more precise, the driving force is the<i>rate of increase</i>in costs—the fact that health care costs have been rising at about twice the rate of inflation. It is this feature of health care that has transformed
Trends in Deaths From Systemic Lupus Erythematosus--United States, 1979-1998
Journal: JAMA (2002)

Systemic lupus erythematosus (SLE) is a serious autoimmune disease of unknown etiology that can affect several organs. Because SLE affects connective tissues and because painful joints and arthritis are among its most common manifestations, this disease is classified with arthritis and other rheumatic diseases. SLE is one of the more fatal forms of rheumatic diseases and non-Causcasian race is a risk factor for death from SLE; however, trends in death from SLE have not been analyzed recently. To characterize deaths from SLE, CDC reviewed SLE deaths during 1979-1998. This report presents the results of that analysis, which indicate that marked age-, sex-, and race-specific disparities exist in SLE death rates and that death rates have increased by approximately 70% during the study period among black women aged 45-64 years. Prevention of deaths requires early recognition and diagnosis of SLE and appropriate therapeutic management.
A Pilot Randomized Trial Comparing Standard Pain Control with or without Gabapentin for the Treatment of Pain Related to Radiation-Induced Mucositis in Head and Neck Cancer
Authors: T. Kataoka, N. Kiyota, T. Shimada, Y. Imamura, N. Chayahara, M. Toyoda, Y. Funakoshi, H. Tomioka, Y. Fujiwara, K. Nibu, T. Komori, H. Nishimura, R. Sasaki, T. Mukohara, H. Minami
Journal: Annals of Oncology (2012)
Diagnostic and Therapeutic Technology Assessment (DATTA)
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal