tbuckley/cabot-search huggingface dataset:
Neurological Pathophysiology
Authors: Charles M. Poser
Journal: JAMA (1974)

Recent years have seen a proliferation of textbooks and mini-textbooks exhibiting a wide variation of quality. This volume stands out in many ways: it addresses itself specifically to known and postulated pathophysiologic mechanisms without being overburdened with details that would interest only the superspecialist; it is concisely and clearly written, and clearly succeeds in its avowed purpose of providing the answers regarding the why and how of neurologic disease; and it is refreshingly free of the cookbook type of approach. Most important, however, it vigorously imparts the excitement and intellectual stimulation to be derived from applying the basic neurological sciences to clinical problems. In a book that is surprisingly comprehensive, it was disappointing not to find any discussion of the pathophysiology of the effects of two common and important diseases on the nervous system, alcoholism and diabetes. The single major criticism relates to the statements about the cerebrospinal fluid (CSF)
CHICAGO HEALTH DEPARTMENT AND PURE-FOOD LEGISLATION.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Airborne Arsenic Exposure and Excretion of Methylated Arsenic Compounds
Authors: T. J. Smith, E. A. Crecelius, J. C. Reading
Journal: Environmental Health Perspectives (1977)

First void urine samples were collected from copper smelter workers exposed to inorganic arsenic and from unexposed controls. Arsenic compounds (As (III), As (V), methylarsonic acid and dimethylarsinic acid) in these samples were analyzed by selective volatilization as arsines with determination of arsenic by plasma excitation emission spectrometry. On the day preceding the urine sample collection a breathing zone measurement was made of respirable arsenic particulates for each subject. It was found that all of the subjects, including the controls excreted arsenic primarily as methylated species. Approximately 50% of the total arsenic was excreted as dimethylarsinic acid and 20% as methylarsonic acid. Slight differences in the proportion of various arsenic compounds were observed with varying levels of inorganic arsenic exposure. Amounts of arsenic species were all closely correlated with each other and with exposure. Irrespirable particulate exposures were measured on a subset of high exposure workers. Irrespirable arsenic was found to be more closely correlated with excretion of arsenic compounds than was respirable arsenic.
Highlights from this issue
Authors: Andrew Bush, Ian Pavord
Journal: Thorax (2014)

Famously, the anti-European party UKIP failed to do well in the elections in London because, as a spokesperson stated as her foot disappeared down her throat and out of her bottom, 'London is full of young educated people'.This issue of Thorax, produced by and for educated people of all ages, celebrates our European friends, to coincide with the ERS in Munich.We have a European themed cover, manuscripts from all over Europe and would like more.
ASSOCIATION NEWS.
Authors: Frank Woodbury
Journal: JAMA (1891)

<h3>American Medical Association.</h3><h3>RAILROAD ARRANGEMENTS.</h3> We are able to announce that arrangements have been made with the Pennsylvania Central, the Baltimore and Ohio, and the "<i>Big Four</i>," the three great through lines from Chicago to Washington, by which Physicians and their families can obtain transportation with return tickets at one and one third rates. Dr. Atkinson, the Secretary of the Association, informs us that the Western Passenger Association has refused to grant commutation upon the following roads: the Atchison, Topeka &amp; Santa Fe, Burlington, Cedar Rapids &amp; Northern, Burlington &amp; Missouri, Chicago &amp; Alton, Chicago &amp; Northwestern, Chicago, Burlington &amp; Northern, Chicago, Burlington &amp; Quincy, Chicago, Milwaukee &amp; St. Paul, Chicago, Rock Island &amp; Pacific, Chicago, St. Paul, Minneapolis &amp; Omaha, Chicago, St. Paul &amp; Kansas, Hannibal &amp; St. Joseph, Kansas City, St. Joseph &amp; Council Bluff, Illinois Central, Iowa Central, Milwaukee &amp; Northern, Milwaukee, Lake Shore &amp; Western, Minneapolis
INTRODUCTORY ADDRESS.
Authors: T. D. CROTHERS
Journal: JAMA (1896)

This Section of Neurology and Medical Jurisprudence has reached a position in the department of medicine of intense practical interest. Every practitioner is confronted with questions of neurology, and the legal relations and possibilities which are constantly springing out of the present conditions. Nerve strains and drains, and vast complex states of neurosis are increasing yearly. Half a dozen text-books and a score or more of pamphlets, and monographs have been published in English during the past year, exclusively on nerve diseases. This is only a small part of the literature which is appearing in journals devoted to this specialty, and in society reports and general journals of medicine. The topic of medical jurisprudence has been enriched with at least four encyclopedic volumes, and over a dozen separate works and almost innumerable papers, lectures, essays, reports of cases, and the renewed activity in the many societies devoted to this special
Antiepileptic Drugs
Authors: Charles M. Poser
Journal: JAMA (1982)

The management of epilepsy constitutes a major part of the practice of neurology. It is not only a common illness, but it is one where the physician's skill and knowledge can make the difference between permitting the patient to lead a normal, productive life or condemning the patient to unemployment, despair, and disability. Indeed, there are few diseases where the advances in the pharmacologic treatment have had such dramatically beneficial effects on clinical practice. This book brings together the very latest in our knowledge of the mode of action, side effects, pharmacokinetics, and many other aspects of anticonvulsant drugs. It is an essential compendium for all neurologists and for all investigators who are directly or indirectly concerned with epilepsy. The list of contributors is in itself assurance of the highest quality; the editors richly deserve the unofficial title of the "Three Kings of Epilepsy." It is remarkable that the treatment
MUDENG (mu-2 related death-inducing gene) overexpression accelerates liver fibrosis in carbon tetrachloride-induced cirrhosis
Authors: Ju-Yeon Cho, JungHee Park, Ji-Hye Han, Seung-Hyun Myung, Tae-Hyoung Kim, Jung Hee Kim, Won Sohn, Chan Guk Park, Young Dae Kim, Man Woo Kim
Journal: Journal of Hepatology (2020)
Idiopathic thrombocytopenic purpura in pregnancy. Successful management with immunoglobulin infusion
Authors: V. L. Rose
Journal: JAMA (1985)

IMMUNE thrombocytopenic purpura (ITP) is a syndrome of persistent thrombocytopenia resulting from antibody-induced destruction of platelets. Since it occurs most commonly in women during their reproductive years, ITP and pregnancy may be concomitant. We present a case of ITP during pregnancy, with an initial response to steroids that later became refractory, necessitating an alteration in therapy. <h3>Report of a Case</h3> A 30-year-old woman, gravida 3, para 2, was found to have thrombocytopenia on her first prenatal visit. She had no history of bleeding or bruising. On physical examination, there was no lymphadenopathy or hepatosplenomegaly. She had petechiae on her lower extremities. The white blood cell count was 12,200/cu mm; hemoglobin level, 13.5 g/dL; hematocrit, 40.6%; and platelet count, 33,000/cu mm. A peripheral blood smear had markedly decreased platelets with occasional giant forms. The bone marrow aspiration had increased megakaryocytes. Platelet-associated IgG antibody level was measured at 62 femtograms (fg)/platelet (normal,
IMMUNOTHERAPY
Authors: M. J. Hickey, C. K. Malone, K. L. Erickson, L. E. Gerschenson, A. H. Lin, A. Inagaki, K. Hiraoka, N. Kasahara, B. Mueller, C. A. Kruse, S. Kong, B. Tyler, J. Zhou, B. S. Carter, H. Brem, R. P. Junghans, P. Sampath, R. K. Lai, L. D. Recht, D. A. Reardon, N. Paleologos, M. Groves, M. R. Rosenfeld, T. Davis, J. Green, A. Heimberger, J. Sampson, N. Hashimoto, A. Tsuboi, Y. Chiba, N. Kijima, Y. Oka, M. Kinoshita, N. Kagawa, Y. Fujimoto, H. Sugiyama, T. Yoshimine, S. M. Birks, M. Burnet, G. J. Pilkington, J. S. Yu, C. J. Wheeler, J. Rudnick, M. Mazer, H. Q. Wang, M. A. Nuno, J. E. Richardson, X. Fan, J. Ji, R. M. Chu, J. G. Bender, E. W. Hawkins, K. L. Black, S. Phuphanich, I. F. Pollack, R. I. Jakacki, L. H. Butterfield, H. Okada, M. A. Hunt, G. E. Pluhar, B. M. Andersen, J. L. Gallardo, C. O. Seiler, K. S. SantaCruz, J. R. Ohlfest, D. F. Bauer, L. S. Lamb, D. K. Harmon, X. Zheng, A. K. Romeo, G. Y. Gillespie, J. N. Parker, J. M. Markert, V. L. Jacobs, R. P. Landry, J. A. De Leo, J. E. Bromberg, J. Doorduijn, J. W. Baars, G. W. van Imhoff, R. Enting, M. J. van den Bent, K. A. Murphy, J. Bedi, A. Epstein, J. R. Ohlfest, M. Olin, B. Andersen, L. Swier, J. Ohlfest, A. J. Litterman, D. M. Zellmer, J. R. Ohlfest, E. A. Chiocca, L. K. Aguilar, E. Aguilar-Cordova, A. G. Manzanera, K. R. Harney, J. Portnow, B. Badie, M. Lesniak, S. Bell, A. Ray-Chaudhuri, B. Kaur, J. Hardcastle, R. Cavaliere, J. McGregor, S. Lo, A. Chakarvarti, J. Grecula, H. Newton, T. W. Trask, D. S. Baskin, P. Z. New, J. Zeng, A. P. See, J. Phallen, Z. Belcaid, N. Durham, C. Meyer, E. Albesiano, G. Pradilla, E. Ford, H. Hammers, B. Tyler, H. Brem, P. T. Tran, D. Pardoll, C. G. Drake, M. Lim, A. Ghazi, A. Ashoori, P. Hanley, V. Salsman, D. R. Schaffer, Z. Grada, Y. Kew, S. Z. Powell, R. Grossman, M. E. Scheurer, A. M. Leen, C. M. Rooney, C. M. Bollard, H. E. Heslop, S. Gottschalk, N. Ahmed, J. Hu, C. Patil, M. Nuno, C. Wheeler, J. Rudnick, S. Phuphanich, M. Mazer, H. Q. Wang, R. Chu, K. Black, J. Yu, A. Marabelle, H. Kohrt, J. Brody, R. Luong, V. Tse, R. Levy, Y. M. Li, H. Jun, M. Shahryar, V. A. Daniel, H. A. Walter, I. Thaipisuttikul, E. Avila, D. A. Mitchell, G. E. Archer, H. S. Friedman, J. E. Herndon, D. D. Bigner, J. H. Sampson, L. A. Johnson, G. E. Archer, S. K. Nair, R. Schmittling, E. Reap, J. H. Sampson, D. A. Mitchell, Y. M. Li, M. Shahryar, H. Jun, V. A. Daniel, H. A. Walter, J. P. Knisely, H. Kluger, J. Flanigan, M. Sznol, J. B. Yu, V. L. Chiang, R. M. Prins, W. Kim, H. Soto, D. N. Lisiero, D. N. Lisiero, L. M. Liau
Journal: Neuro-Oncology (2011)
The Resident Voice in Organized Medicine
Journal: JAMA (1979)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
DERMATOLOGY IN TUDOR AND EARLY STUART ENGLAND
Authors: P. W. M. COPEMAN, W. S. C. COPEMAN
Journal: British Journal of Dermatology (1970)

Journal Article DERMATOLOGY IN TUDOR AND EARLY STUART ENGLAND Get access P. W. M. COPEMAN, P. W. M. COPEMAN Skin Department, Westminster Hospital, London, S.W.1, and Faculty of the History of Medicine, Worshipful Society of Apothecaries, Blackfriars Lane, London E.C. 4 Search for other works by this author on: Oxford Academic Google Scholar W. S. C. COPEMAN W. S. C. COPEMAN Skin Department, Westminster Hospital, London, S.W.1, and Faculty of the History of Medicine, Worshipful Society of Apothecaries, Blackfriars Lane, London E.C. 4 Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 82, Issue 1, 1 January 1970, Pages 78–88, https://doi.org/10.1111/j.1365-2133.1970.tb02197.x Published: 01 January 1970 Article history Accepted: 28 May 1969 Published: 01 January 1970
Utilization of DNA-Protein Cross-Links as a Biomarker of Chromium Exposure
Authors: Anatoly Zhitkovich, Victoria Voitkun, Tomasz Kluz, Max Costa
Journal: Environmental Health Perspectives (1998)

Human exposure to carcinogenic Cr(VI) compounds is found among workers in a large number of professional groups, and it can also occur through environmental pollution.A significant number of toxic waste sites contain Cr as a major contaminant.In this paper we summarize our efforts to apply measurements of DNA-protein cross-links (DPC) as a test for biologically active doses of Cr(VI).DPC were found at elevated levels in lymphocytes in several human populations with low to medium Cr exposures.At high exposure to Cr(VI), exemplified by a group of Bulgarian chrome- platers, DPC plateaued and adducts' levels were similar to those found in environmentally exposed individuals.Lymphocytic DPC correlated strongly with Cr levels in erythrocytes that are indicative of Cr(VI) exposure.DPC in lymphocytes were not confounded by such variables as smoking, age, body weight, gender, or ethnicity.A new version of the cross-link assay offers improved sensitivity and requires a small amount of biologic material.Preliminary results indicate that the ability of DPC to reach detectable levels at low levels of Cr exposure could be related to a lack of repair of these lesions in lymphoid cells.Cr(lll)-mediated cross-links of DNA with peptide glutathione or single amino acids were mutagenic in human cells, with a relationship of higher molecular weight of the peptide/amino acid correlating with a more potent mutagenic response.We speculate that bulky DPC could also have a significant promutagenic effect.The current methodology does not allow specific determination of Cr-induced DPC; however, demonstrated sensitivity of DPC measurements and the assay's large sample capacity may allow this assay to be used as the initial screening test for the occurrence of DNA damage in Cr(V1)-exposed populations.
What You Should Know About Heart Disease
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
In This Issue/Research Watch/News-in-Brief/News from the IASLC Tobacco Control Committee
Journal: Journal of Thoracic Oncology (2017)

This brief report described the first clinical evidence of efficacy from the combination of firstand third-generation EGFR tyrosine kinase inhibitors in a patient with advanced lung adenocarcinoma harboring EGFR C797S in trans with T790M.Capturebased sequencing was performed on longitudinal plasma samples obtained from the patient at different treatment milestones.Concomitant EGFR C797S in trans and EGFR T790M was observed at development of resistance to osimertinib.Combination of erlotinib and osimertinib resulted in partial response in the patient and undetectable EGFR C797S.The disease progressed following 3 months of progression-free survival in conjunction with EGFR C797S in cis with T790M, indicating the clonal progression of C797S from in trans to in cis at disease progression as a possible resistance pathway (p.1723).Multidisciplinary Tumor Board Decision Making for Postoperative Radiotherapy in Thymic Epithelial Tumors: Insights from the RYTHMIC Prospective Cohort Decisions on postoperative radiotherapy (PORT) made at a national multidisciplinary tumor board (MTB) in France (2012-2015) were evaluated for alignment with guidelines from RYTHMIC, the nationwide network for thymic epithelial tumors (TET), and implementation in patients.The analysis included 274 patients, of whom 89% had thymoma and 11% had thymic carcinoma.Majority of the decision of the MTB (92%) was in agreement with guidelines in patients with stage I-III TET.MTB decision of PORT treatment was observed for 43% (117) patients, and 101 patients ultimately received PORT.More than 3month delay after surgery was the most common reason PORT was not delivered.The International Thymic Malignancy Interest Group-defined dose-volume constraints were followed in all patients except 4. All in all, the findings demonstrated the decision-making process for PORT in TET, and underscored the importance of systematic review at an MTB and following current guidelines (p.1715).
Journal of Endocrinology, London
Journal: JAMA (1970)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Marihuana and tidal volume
Authors: Robert Schwin, Donald W. Goodwin, Shirley Y. Hill
Journal: JAMA (1973)

<h3>To the Editor.—</h3> In the 19th century, cannabis products were commonly used in the treatment of asthma.<sup>1-3</sup>Smoking marihuana, on the other hand, is associated with bronchitis and other deleterious effects on lung function.<sup>4</sup>The present report deals with acute marihuana effects on pulmonary capacity in nonasthmatic regular marihuana smokers. <h3>Method.—</h3> Thirty-one healthy men between the ages of 21 and 30 years who had smoked marihuana frequently for at least two years were studied; more than half had smoked marihuana at least once a week for four or more years. About half were cigarette smokers. None had current respiratory complaints or a history of pulmonary disease. Subjects were randomly assigned to a marihuana group (N =15) or placebo group (N = 16). The marihuana contained 1.5% tetrahydrocannabinol (THC), while the placebo consisted of cannabis tobacco with THC removed. The National Institute of Mental Health provided the drug and the placebo.
Section 19.—Psoriatic Arthritis
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Is poststreptococcal glomerulonephritis progressive?
Journal: BMJ (1977)

Is poststreptococcal glomerulonephritis progressive?The great epidemics of scarlatina that swept through the crowded cities of Europe in the seventeenth to nineteenth centuries taught doctors that nephritis with bloody urine could follow the acute attack and on occasion kill the sufferer.'When the streptococcus was isolated in 1881 it became the first specific antecedent of nephritis to be recognised.Previously, Bright had described the three classic phases of nephritis as one inexorable sequence: acute nephritis, nephrotic syndrome, uraemia, death.2Immediately, others suggested that in fact these three archetypes might represent distinct diseases with the acute phase having a more benign outcome.Exponents of the unitary hypothesis explained the frequent absence of direct evidence connecting acute nephritis with the chronic phases by postulating a chronic latent phase of clinically quiescent or even inapparent disease after the acute episode followed by insidious entry into the later stages.This nineteenth-century debate is still with us.Today in Britain most patients who present with an acute onset of haematuria accompanied by variable hypertension, oliguria, oedema, and uraemia-the acute nephritic syndrome -have no evidence of streptococcal infection as the pre- cipitating factor.Indeed, acute poststreptococcal nephritis is now rare in Britain.