tbuckley/cabot-search huggingface dataset:
Depression of cellular immunity as an index of malnutrition in surgical patients
Authors: K S Nair, J. Garrow
Journal: BMJ (1981)

2-6 days (range 1-5 days).The mean interval between top-ups was 12 hours (range 4-30 hours).Ten patients thought their symptomatic foot was warmer.Of the eight cannula tips sent for bacterial culture, all were sterile.Seven of the nine patients who received grafts experienced good pain relief as a result of surgery.Two patients with poor "run-off" and gangrene were unimproved and subsequently underwent major amputation.
Asthma
Authors: Christopher H. Fanta
Journal: New England Journal of Medicine (2009)

Current estimates suggest that as many as 300 million people worldwide have asthma and atopy. Yet despite the persistently high prevalence of disease, the most recently available data indicate improved outcomes, with fewer annual hospitalizations for asthmatic attacks and fewer asthma-related deaths. Improved management is a likely reason for this improved outcome. This article discusses recent advances and current practice in the management of asthma.
Energy-Related Pollutants in the Environment: Use of Short-Term Tests for Mutagenicity in the Isolation and Identification of Biohazards
Authors: J. L. Epler, F. W. Larimer, T. K. Rao, C. E. Nix, T. Ho
Journal: Environmental Health Perspectives (1978)

In an effort to gather information on the potential genetic hazards of existing or proposed energy-generating or -conversion systems, we have begun a correlated analytical and genetic analysis of a number of technologies. The work is divided into two phases: one deals with known compounds expected to occur in the environment through energy production, conversion, or use; the other deals with actual samples from existing or experimental processes. To approach the problems of coping with and testing large numbers of compounds, we set up a form of the “tier system.” Operating units utilizing Salmonella, Escherichia coli, yeast, human leukocytes, mammalian cells, and Drosophila have been initiated. Various liquid-liquid extraction methods and column chromatographic separations have been applied to crude products and effluents from oil-shale, coal-liquefaction, and coal-gasification processes. Mutagenicity of the various fractions is assayed by means of reversion of histidine-requiring auxotrophs of Salmonella typhimurium; comparative studies are carried out with the other genetic systems. In order to incorporate metabolic activation of these fractions and compounds, rat liver homogenates (S-9) are used in the various assays. Results implicate chemicals occurring in the basic (ether-soluble) and the neutral fractions as potential genetic hazards. Chemical constituents of these fractions (identified or predicted) were tested individually for their mutagenic activity.
Letter: Vaccination of smallpox contacts.
Authors: G Bousfield, G Dick
Journal: BMJ (1974)

to draw the attention of the profession to the fact that gonococcal infection of the pharynx occurs, that the clinical condition is sometimes severe and, contrary to the find- ings here, not always accompanied by genital infection, and also that our knowledge of the sexual practices of the population is scanty.-Iam, etc.,
Comparative Effects of Ticrynafen and Hydrochlorothiazide in the Treatment of Hypertension
Journal: New England Journal of Medicine (1979)

Two dose levels of ticrynafen, a new uricosuric diuretic, and of hydrochlorothiazide were randomly assigned, double-blind to 240 men with initial diastolic blood pressures in the range of 95 to 114 mm Hg. A dose of 500 mg of ticrynafen once daily exerted an antihypertensive effect comparable to that of 50 or 100 mg of hydrochlorothiazide. Whereas serum uric acid levels rose in patients treated with hydrochlorothiazide, they fell markedly in those receiving ticrynafen. Otherwise, both diuretics produced similar chemical changes in serum. Patients tolerated ticrynafen as well as they did hydrochlorothiazide over a period of six months of observation, and there was no evidence of serious toxicity or loss of therapeutic effect with ticrynafen. This antihypertensive agent, in appropriate doses, appears to be as effective and well tolerated as hydrochlorothiazide, and in addition ticrynafen prevents hyperuricemia.
Reply
Authors: C.A. Walton, C. H. Dash
Journal: British Journal of Dermatology (1983)

Journal Article Reply Get access C.A. Walton, C.A. Walton Formulation Dept. Pharmacy Division Glaxo Group Research Greenford, Middlesex Search for other works by this author on: Oxford Academic Google Scholar C. H. Dash C. H. Dash Medical Division Glaxo Pharmaceuticals Ltd. Greenford, Middlesex Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 108, Issue 2, 1 February 1983, Page 250, https://doi.org/10.1111/j.1365-2133.1983.tb00071.x Published: 01 February 1983
Hypertension
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phenylketonuric Families
Authors: Mary L. Efron
Journal: JAMA (1965)

The conclusions which must be drawn from the data on early detection of phenylketonuria (PKU) reported by Berry et al inThe Journalof Aug 24, 1964 (<b>189</b>:641), are different from those reported by Allen and Wilson inThe Journalof May 25, 1964 (<b>188</b>:720). On the basis of three phenylketonuric patients who had positive ferric chloride tests in the first eight days of life (and seven others aged 17 to 54 days with positive tests) Allen challenged the accepted view that the ferric chloride test is not of great value in early infancy. An editorial inThe Journal(<b>188</b>:748 [May 25] 1964) commenting on Allen's paper stated, "It is recommended that a positive blood test should always be followed by a urine test, and treatment should not be initiated until the urine test becomes positive...." Berry et al tested 17 newborn sibs of known phenylketonurics. Of
Highlights
Journal: JAMA (2019)

Disposable N95 fi ltering facepiece respirators prevent the inhalation of small airborne particles; medical masks prevent hand-to-face contact and facial contact with large droplets and sprays.For the ResPECT Investigators, Radonovich and colleagues randomized 2862 health care workers in 137 outpatient settings who were exposed to patients with suspected or confi rmed respiratory illness and found no signifi cant diff erence in the incidence of laboratory-confi rmed infl uenza for workers assigned to wear N95 respirators vs medical masks.In an Editorial, Talbot and Babcock note that mandatory infl uenza vaccination policies for health care workers have been shown to reduce symptomatic absenteeism.
Chemical Wastes, Children's Health, and the Superfund Basic Research Program
Authors: Philip J. Landrigan, William A. Suk, Robert W. Amler
Journal: Environmental Health Perspectives (1999)

Three to 4 million children and adolescents in the United States live within 1 mile of a federally designated Superfund hazardous waste disposal site and are at risk of exposure to chemical toxicants released from these sites into air, groundwater, surface water, and surrounding communities. Because of their patterns of exposure and their biological vulnerability, children are uniquely susceptible to health injury resulting from exposures to chemical toxicants in the environment. The Superfund Basic Research Program, funded by the U.S. Environmental Protection Agency and directed by the National Institute of Environmental Health Sciences, is extremely well positioned to organize multidisciplinary research that will assess patterns of children's exposures to hazardous chemicals from hazardous waste disposal sites; quantify children's vulnerability to environmental toxicants; assess causal associations between environmental exposures and pediatric disease; and elucidate the mechanisms of environmental disease in children at the cellular and molecular level.
Formation of Mutagens by Heating Foods and Model Systems
Authors: D. Yoshida, T. Matsumoto, H. Okamoto, S. Mizusaki, A. Kushi, Y. Fukuhara
Journal: Environmental Health Perspectives (1986)

We have demonstrated that the pyrolysis products of amino acids and proteins in model systems are mutagenic. The mutagenic principles in the pyrolyzates of amino acids have been isolated and identified by Sugimura et al. We have isolated and identified amino-alpha-carbolines from pyrolyzed soybean globulin as mutagens. The yield of mutagens by the heating of food constituents is changed by the heating method. Effects of heating methods on the yield of amino-alpha-carbolines were studied in a series of experiments, and the results are shown in this paper. Additionally, it has been shown that by the heating of creatine-sugar mixtures imidazoquinoline or quinoxaline mutagens are formed.
From the Shepherd Magnes.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum
Journal: New England Journal of Medicine (1942)

appearing on the 28th day of illness was thought to be due to sulfathiazole therapy.An intravenous pyelogram on May 27 was negative for obstruction or renal damage, except for slight stasis in the right kidney.On May 21, the patient suddenly developed a partial left hemiplegia following 2 days of numbness of the left April ûay of month]5 10 15 20 ûay ofdisease] 5 10 15 20 25 102temperature igg
Comparison of critical care provided by family physicians and general internists
Authors: B. L. Hainer
Journal: JAMA (1988)

Privilege conflicts and credentialing issues involving family physicians' care of hospitalized patients are controversial areas. This study compares the process and outcome of critical care provided by family physicians and general internists. We studied 523 patients admitted by these specialists to the medical intensive and cardiac care units of a large regional hospital over a one-year period. The length of stay and readmission rate in the intensive care unit and hospital, severity of illness, discharge diagnosis, proportion who died, time until death of those who died, consultation rate, and hospital charges did not differ significantly between patients cared for by physicians in the two specialties. Application of Cox's proportional hazard model to the data indicated the risk of death to be significantly related to patient race, age, and severity of illness, but not to physician specialty. Regression analysis of several morbidity variables showed no relationship to physician specialty. Lack of differences in outcome and process in the hospital studied leads us to believe that both family physicians and general internists are entitled to have equal access to the care of patients in critical care units. (<i>JAMA</i>1988;260:354-358)
Nitrous Oxid-Oxygen Analgesia and Anaesthesia in Normal Labor and Operative Obstetrics.
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chlamydial pneumonia and asthma: a potentially important relationship
Authors: R. C. Bone
Journal: JAMA (1991)

In this issue of<i>JAMA</i>, Hahn et al<sup>1</sup>document an interesting relationship between chlamydial pneumonia and asthma in adults using a matched comparison method. These investigators found that patients with serologically confirmed<i>Chlamydia pneumoniae</i>infection (antibody titers greater than 1:64) were much more likely to develop bronchial asthma subsequent to their chlamydial infection than were seronegative patients (antibody titers less than 1:16). Nearly 30% of the<i>Chlamydia</i>-exposed (seropositive) patients were later diagnosed as having asthmatic bronchitis, whereas only 7% of unexposed (seronegative) patients received the same diagnosis in the 6-month period after their respiratory illness. The context for this finding is a trend toward increasing incidence, morbidity, and mortality attributable to asthma— despite advances in diagnosis and treatment. During the 1980s, statistics relating to asthma showed distinct increases in mortality in the United States and in most industrialized countries.<sup>2,3</sup>Furthermore, a recent article demonstrated
Human Health Risk Assessment in Relation to Environmental Pollution of Two Artificial Freshwater Lakes in The Netherlands
Authors: Harma J. Albering, Jean-Paul Rila, Edwin J. C. Moonen, Jurian A. Hoogewerff, Jos C. S. Kleinjans
Journal: Environmental Health Perspectives (1999)

A human health risk assessment has been performed in relation to recreational activities on two artificial freshwater lakes along the river Meuse in The Netherlands. Although the discharges of contaminants into the river Meuse have been reduced in the last decades, which is reflected in decreasing concentrations of pollutants in surface water and suspended matter, the levels in sediments are more persistent. Sediments of the two freshwater lakes appear highly polluted and may pose a health risk in relation to recreational activities. To quantify health risks for carcinogenic (e.g., polycyclic aromatic hydrocarbons) as well as noncarcinogenic compounds (e.g., heavy metals), an exposure assessment model was used. First, we used a standard model that solely uses data on sediment pollution as the input parameter, which is the standard procedure in sediment quality assessments in The Netherlands. The highest intake appeared to be associated with the consumption of contaminated fish and resulted in a health risk for Pb and Zn (hazard index exceeded 1). For the other heavy metals and for benzo(a)pyrene, the total averaged exposure levels were below levels of concern. Secondly, input data for a more location-specific calculation procedure were provided via analyses of samples from sediment, surface water, and suspended matter. When these data (concentrations in surface water) were taken into account, the risk due to consumption of contaminated fish decreased by more than two orders of magnitude and appeared to be negligible. In both exposure assessments, many assumptions were made that contribute to a major degree to the uncertainty of this risk assessment. However, this health risk evaluation is useful as a screening methodology for assessing the urgency of sediment remediation actions.
A Textbook on the Nursing and Diseases of Sick Children for Nurses by Various Authors.
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Ekzem und Urtikaria.
Journal: JAMA (1926)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tapetoretinal Degeneration
Authors: A. B. Grossman
Journal: BMJ (1972)

Treatment of Urinary Schistosomiasis SIR,-In the leading article "Chemotherapy in Schistosomiasis" (15 January, p. 128) no reference was made to trichlorphon (metriphonate) for treating urinary schistosomiasis.This drug was used to treat hundreds of infected people in Tanzania with results which were uniformly excellent.1-3There were no toxic side-effects when 7.5 mg/kg were given by mouth at intervals of two or more weeks, there was no evidence of cumulative effects, and the capsules being tasteless were readily accepted by patients.Under favourable conditions the permanent cure rate is 100%.The drug is very cheap, much cheaper than antimony, niridazole, or hycanthone.Trichlorphon does not cure patients with intestinal schistosomiasis.'-I am, etc.,
Oesophageal achalasia mistaken for anorexia nervosa.
Authors: K. M. Pagliero
Journal: BMJ (1992)

their general practitioner.Taking into considera- tion the points already made about possible reasons for their visit to the department and the general nature of the question asked, the figure does not seem to differ from that found in other studies.2The study asked a vague general question about consultations with a general practitioner before the visit to the accident and emergency department and consequently got vague general data, from which no conclusions can be drawn.Perhaps more disturbing is the implied criticism of general practitioners' diagnostic ability.I hope that I am being hypersensitive after my second 120 hour week this month and that no such criticism was meant.
Ophthalmology
Authors: J. I. Perlman
Journal: JAMA (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal