tbuckley/cabot-search huggingface dataset:
Medical News.
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
1,569 COURSES IN 1964-1965 LIST
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Membership of Committees on Education (as of July 1, 1995)
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 4197: Does Relative Wall Thickness or Left Ventricular Mass Index Best Predict Mortality Risk in Patients With Preserved Systolic Function?
Authors: Dharmendrakumar A Patel, Carl J Lavie, Sangeeta Shah, Yvonne Gilliland, Richard V Milani
Journal: Circulation (2008)

Background: Several studies have indicated that left ventricular (LV) geometric patterns predict cardiovascular events. However, little data is available that compares the relative prognostic impact of LV mass index (LVMI) and relative wall thickness (RWT) on mortality in a large cohort of patients with preserved systolic function. Methods: The impact of LVMI and RWT on mortality during an average follow-up of 1.7±1.0 years was examined in a sample of 47,701 patients (mean age: 61.6 ± 15.4; females=54.6 %) with preserved ejection fraction(EF), as well as in age groups of &lt;50 yrs(n=10,864; mean age=39.9 ± 8.1; females=58.4 %), 50 –70 yrs (n=20,181; mean age=59.9 ± 5.7; females=52.2 %) and &gt;= 70 yrs (n=16,836; mean age=77.7 ± 5.5; females=55.1 %). Results: With increasing age (&lt;50, 50 –70, &gt;=70 yrs), both LVMI (78.5 ± 23.4, 84.3 ± 25.4, 90.3 ± 27.6; p&lt;0.0001) and RWT (0.37 ± 0.08, 0.41 ± 0.08, 0.43 ± 0.09; p&lt;0.0001) as well as mortality (2.2%, 5.0%, 14.2%; p&lt;0.0001) showed significant linear trends and were independent predictors of mortality (Table , Figure ). Conclusion: Although, both LVMI and RWT were independently associated with increased mortality in all groups, RWT was by far the strongest independent predictor of all-cause mortality, especially in younger patients.
Irish Journal of Medical Science, Dublin
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Wrong Page Number
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Radiologic Examination of the Gastrointestinal Tract
Authors: John E. Gary, Richard Schatzki
Journal: New England Journal of Medicine (1954)

ADVANCES in the radiologic examination of the gastrointestinal tract have not been touched on in this section for more than ten years. With few exceptions, only the more recent papers on various topics are reviewed here, with emphasis on subjects in which interest is most active.The EsophagusCongenital DuplicationFrank and Paul1 reported the first case of duplication diagnosed before death. A swallow of barium was seen to enter one large and one small canal in the lower two thirds of the esophagus. The two canals united just above the diaphragm. The patient was ten years old, and on . . .
PURULENT BRAIN DEPOSITS, AND PHLEBITIS AND THROMBOSIS OF THE CEREBRAL VEINS AND SINUSES FOLLOWING EAR DISEASE.
Authors: FRANK ALLPORT
Journal: JAMA (1892)

A few years ago, when the mastoid process was first opened for the liberation of pus contained within its walls, it was regarded as an extremely hazardous procedure, necessitating the highest skill, and unwarrantable except as a<i>dernier resort</i>. As the anatomical and pathological bearings of the disease become better understood, the operation assumed a less formidable appearance, and the process is now opened sufficiently early to save most cases of this nature. Intra-cranial lesions following aural affections have a somewhat similar history, but our knowledge and plans of procedure are still in a primitive condition, and not sufficiently crystallized to warrant a sense of security, when radical and positive steps appear to be indicated. With the hope of somewhat systematizing our present knowledge of this subject, I have been to the pains of collecting the data of 169 cases bearing on the topic, and no case has been admitted
Mutant p53 Prolongs NF-kB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer
Authors: Tomer Cooks, Ioannis S. Pateras, Ohad Tarcic, Hilla Solomon, Aaron J. Schetter, Sylvia Wilder, Guillermina Lozano, Eli Pikarsky, Tim Forshew, Nitzan Rosenfeld, Noam Harpaz, Steven Itzkowitz, Curtis C. Harris, Varda Rotter, Vassilis G. Gorgoulis, Moshe Oren
Journal: Cancer Cell (2013)
Society and Disease
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cytokine Production by Bronchoalveolar Lavage Cells in Chronic Beryllium Disease
Authors: Sally S. Tinkle, Patricia W. Schwitters, Lee S. Newman
Journal: Environmental Health Perspectives (1996)

Chronic beryllium disease (CBD) begins as a sensitizing cell-mediated immune response to beryl- lium antigen that progresses to granulomatous lung disease.Previous studies demonstrated the involvement of proinflammatory cytokines in the disease process, but the pattern and regulation of cytokine release is unknown.Using bronchoalveolar lavage (BAL) cells from CBD patients in short-term tissue culture, we evaluated cytokine protein levels by enzyme-linked immunosorbent assay and T-lymphocyte proliferation by tritiated thymidine incorporation.We observed the beryllium-stimulated release of tumor necrosis factor-alpha (TNF-ix), interleukin-6 (IL-6), interleukin-2 (IL-2), and interferon-gamma (IFN-y) but not interleukin-4 (IL-4).Beryllium-stimulated IFN-y release was sustained to 168 hr in culture, whereas IL-2 concentrations returned to baseline after 24 hr.Neutralization of IL-2 decreased beryllium-stimulated T-lymphocyte proliferation, but the level of proliferation remained elevated in comparison to unstimulated BAL cells.These data suggest that T helper 1 (Thl) lymphocytes participate in the beryllium disease process; that IFN-y levels remain elevated after IL-2 levels return to baseline; and that IL-2 participates directly in beryllium-stimulated T-cell proliferation, but other T-lymphocyte mitogenic cytokines may be involved.
Immune deficiency syndrome in children
Authors: J. Oleske
Journal: JAMA (1983)

The present epidemic of acquired immune deficiency syndrome (AIDS) was originally described in homosexual men and subsequently in intravenous drug abusers, Haitians, and hemophiliacs. Profound defects in cell-mediated immunity (CMI) are associated with Kaposi's sarcoma and a variety of serious opportunistic infections. Recently, we and others have encountered a group of children with an otherwise unexplained immune deficiency syndrome and infections of the type found in adults with AIDS. In this report, we describe eight children from the Newark, NJ, metropolitan area born into families with recognized risks for AIDS. These patients have had recurrent febrile illnesses, failure to thrive, hypergammaglobulinemia, and depressed CMI. Four of these children have died. Our experience suggests that children living in high-risk households are susceptible to AIDS and that sexual contact, drug abuse, or exposure to blood products is not necessary for disease transmission. (<i>JAMA</i>1983;249:2345-2349)
Health insurance values and implementation in The Netherlands and the Federal Republic of Germany. An alternative path to universal coverage
Authors: B. L. Kirkman-Liff
Journal: JAMA (1991)

The health care systems in the Netherlands and the Federal Republic of Germany are based on a set of values that involve mutual obligations between private parties. These obligations are realized through systems incorporating private practice physicians, community and church- and municipality-affiliated hospitals, and nonprofit and for-profit insurers. The underlying values and implementation approaches in these systems provide an alternative to the adoption of a Canadian-style health insurance system. A discussion that focuses on "obligations" rather than "rights" may be a more useful approach for the design of reforms of the American health system in the 1990s. Such a discussion would focus on the mutual responsibility of all parties to create and maintain a universal private health care system. (<i>JAMA</i>. 1991;265:2496-2502)
Diagnosis and treatment of heart failure based on left ventricular systolic or diastolic dysfunction
Authors: W. H. Gaasch
Journal: JAMA (1994)

Data from large and small clinical trials reflect major differences in the pathophysiology, treatment, and prognosis of left ventricular (LV) systolic and diastolic dysfunction. These studies also indicate that medical therapy can benefit patients with LV dysfunction regardless of whether or not they are symptomatic. Because the descriptive term congestive heart failure does not provide for these important distinctions, a new classification of LV dysfunction has been developed in which patients with LV dysfunction are categorized on the basis of normal or abnormal systolic function. This classification is based on a simple assessment of LV function, it is applicable to patients without symptoms, and it reflects differences in treatment and prognosis. Those with clinically significant LV systolic dysfunction (ie, an LV ejection fraction &lt;40%) benefit from therapy whether or not they have symptoms of heart failure. Those with LV dysfunction and a normal LV ejection fraction (ie, diastolic dysfunction) also benefit from medical therapy. Annual mortality is higher in those with systolic dysfunction than in those with diastolic dysfunction, but within each of these categories mortality is higher in those with symptoms than in those without. This classification can be useful in the diagnosis and treatment of individual patients as well as in epidemiologic surveys designed to assess medical practice patterns. (<i>JAMA</i>. 1994;271:1276-1280)
Follicular lymphoma
Authors: Ellen Leich
Journal: HemaSphere (2019)

Take home messages Understand how the genetic landscape, heterogeneity and clonal evolution shapes the pathogenesis of FL. Understand the need for a better risk stratification in FL using novel prognostic factors to identify patients with high-risk FL, in order to guide better risk-adapted therapeutic strategies. Understand that the majority of FL patients diagnosed in 2018 will probably die with the disease and not of the disease and that the increased clinical efficacy of new regimens has thus to be balanced against their adverse effects and quality of life. Follicular lymphoma (FL) is the most frequent indolent non-Hodgkin lymphoma. The risk of tumor-related death and FL-transformation has been significantly reduced thanks to currently available therapies, including first- and second-generation anti-CD20 antibodies, which might be complemented using Pi3K-inhibitors or immunomodulating agents in relapsed-refractory FL patients. Nevertheless, advanced FL remains an incurable disease, which is particularly difficult to treat in 20% to 30% of high-risk FL patients, having a specifically bad outcome. Accurate risk-stratification is thus a medical need. However, none of the prognostic factors identified so far (eg, follicular lymphoma international prognostic index (FLIPI/FLIPI2), total metabolic tumor volume, minimal residual disease), is able to accurately risk-stratify FL patients, alone. Most FL harbor the translocation t(14;18)(q32;q21) and alterations in genes involved in epigenetic regulation. A core set of alterations including the t(14;18) and mutations in epigenetic regulators (eg, MLL2, CREBBP, EZH2) were shared among sequential biopsies and found to be clonal events, suggestive of early driver events. Instead, FL transformation is rather driven by genetic alterations affecting cell cycle regulation, DNA damage response, immune surveillance and NF-κB signaling. Interestingly, the M7-FLIPI, which is based on the FLIPI and the mutation status of 7 genes (incl. 5 epigenetic regulators), allowed to predict the risk of progression to disease within 24 months in ∼80% of high risk FL patients after first-line immunochemotherapy. Moreover, clinical trials with the EZH2-inhibitor Tazemetostat in relapsed/refractory FL showed an overall better response in EZH2-mutant cases. One strategy to improve prognosis and to guide more personalized therapeutic approaches might thus be to combine currently available prognostic factors and to initiate further clinical trials with molecular inhibitors.
Work of Medical Research Council
Journal: BMJ (1965)

The above committee is one of Parliament's select committees that undertake enquiries of considerable depth in their particular fields. Its latest enquiry looked at the MRC in general, and also specifically at how it is handling the Biobank project. Its general findings are scathing of the MRC's performance and mismanagement of its funds, concluding that 'the anger of the research community at MRC's funding problems is not only understandable but entirely justified.' The following are the committee's conclusions and recommendations on Biobank--the collection of blood samples, lifestyle details and medical histories from 500,000 middle-aged Britons, and its general conclusions.
Experimental Physiology.
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ASSOCIATION NEWS.
Journal: JAMA (1890)

<h3>Report of Committee on Dr. Freire's Claim to have Discovered the Yellow Fever Germ.</h3><h3>To the Section on State Medicine of the American Medical Association.</h3> —Your Committee to whom the reports of Drs. Freire and Sternberg were referred for an expression of opinion on the present status of Dr. Freire's claim to have discovered the yellow fever germ, and his ability to prevent the disease by inoculation, respectfully report that Dr. Freire's professed discoveries still need verification. That Dr. Sternberg appears to have made a diligent and experimental study, thoroughly going over the whole ground of Dr. Freire's experiments with such particularity as to carry conviction to the mind of your Committee that the germ of yellow fever is yet to be discovered. A. N.Bell, M.D., R.Rutherford, M.D., C. A.Lindslay, M.D. May 21, 1890. Committee.
The Authors Reply
Authors: Takahiro Kuragano, Osamu Matsumura, Akihiko Matsuda, Taiga Hara, Hideyasu Kiyomoto, Toshiaki Murata, Kenichiro Kitamura, Shouichi Fujimoto, Hiroki Hase, Nobuhiko Joki, Atushi Fukatsu, Toru Inoue, Yukihiro Itakura, Takeshi Nakanishi
Journal: Kidney International (2015)
THE CASE OF THE PINK PORK
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal