tbuckley/cabot-search huggingface dataset:
Medicine Man
Authors: Noel Haukebo
Journal: JAMA (1991)

The young couple who came into my office that day were good-looking and well dressed. The woman was slender and wore a subtly flowered dress that set off her brunette coloring. The man was more casually attired in knit shirt, linen slacks, and loafers. They could have been models on assignment. They were, in fact, the first Native Americans from the nearby reservation to come to our mental health center. The first thing that became apparent was that they were not on the best of terms. The second was that the young woman was not going to utter a word; not then and, as it turned out, not the next day. When I addressed her, she shook her head firmly. It was up to the man to explain that she was along solely as an observer. When I asked the man (let's call him Frank) how I could help, he
Potential Bronchoconstrictor Stimuli in Acid Fog
Authors: John R. Balmes, Jonathan M. Fine, Terry Gordon, Dean Sheppard
Journal: Environmental Health Perspectives (1989)

Acid fog is complex and contains multiple stimuli that may be capable of inducing bronchoconstriction. These stimuli include sulfuric and niric acids, the principal inorganic acids present; sulfites, formed in the atmosphere as a reaction product of sulfur dioxide and water droplets; fog water itself, a hypoosmolar aerosol; the organic acid hydroxymethanesulfonate, the bisulfite adduct of formaldehyde; and gaseous pollutants, e.g., sulfur dioxide, oxides of nitrogen, ozone. Given this complexity, evaluation of the respiratory health effects of naturally occurring acid fog requires assessment of the bronchoconstrictor potency of each component stimulus and possible interactions among these stimuli. We summarize the results of three studies that involve characterization of the bronchoconstrictor potency of acid fog stimuli and/or their interaction in subjects with asthma. The results of the first study indicate that titratable acidity appears to be a more important stimulus to bronchoconstriction than is pH. The results of the second study demonstrate that sulfite species are capable of inducing bronchoconstriction, especially when inhaled at acid pH. The results of the third study suggest that acidity can potentiate hypoosmolar fog-induced bronchoconstriction.
INTRA-AURICULAR PUNCTURE
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Disease States of Pilots Considered A Factor in Some Aircraft Accidents
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
EUGENE LINDSAY OPIE EXPERIMENTAL PATHOLOGIST
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Importance of minor histocompatibility antigen expression by nonhematopoietic tissues in a CD4+ T cell–mediated graft-versus-host disease model
Authors: Stephen C. Jones, George F. Murphy, Thea M. Friedman, Robert Korngold
Journal: Journal of Clinical Investigation (2003)

Minor histocompatibility antigens with expression restricted to the recipient hematopoietic compartment represent prospective immunological targets for graft-versus-leukemia therapy. It remains unclear, however, whether donor T cell recognition of these hematopoietically derived minor histocompatibility antigens will induce significant graft-versus-host disease (GVHD). Using established bone marrow irradiation chimeras across the multiple minor histocompatibility antigen–disparate, C57BL/6→BALB.B combination, we studied the occurrence of lethal GVHD mediated by CD4+ T cells in recipient mice expressing only hematopoietically derived alloantigens. Even substantial dosages of donor C57BL/6 CD4+ T cells were unable to elicit lethal GVHD when transplanted into [BALB.B→C57BL/6] chimeras. Instead, chimeric mice displayed transient cachexia with reduced target-tissue injury over time, reflecting an early, limited, graft-versus-host response. On the other hand, the importance of minor histocompatibility antigens derived from nonhematopoietic tissues was demonstrated by the finding that [C57BL/6→BALB.B] chimeric mice succumbed to C57BL/6 CD4+ T cell–mediated GVHD. These data suggest that severe acute CD4+ T cell–mediated GVHD across this minor histocompatibility antigen barrier depends on the expression of nonhematopoietically rather than hematopoietically derived alloantigens for maximal target-tissue infiltration and injury.
Pulmonary embolization and oral contraceptive
Authors: J. N. Ferguson
Journal: JAMA (1967)

<h3>To the Editor:—</h3> Simple compartmentation of the inferior vena cava by suture and plastic-clip method has been shown to be reasonably effective in preventing lethal pulmonary emboli from lower body sites.<sup>1</sup>Although improvements of the serrarated Teflon clip have been recently reported,<sup>2</sup>several nuisance features remain. The clip is not tailored to vein size, placement of the clip requires some tedious mobilization of the inferior vena cava, and the clip is fixed in place by a tie which is subject to the weaknesses of the operator and the material used. The disadvantages of the Teflon appliances can be obviated by use of clips of universally available Kirschner wire. This simple substitute can provide the frugal surgeon with an available tool in nearly any surgical setting. <h3>Methods and Materials:—</h3> The diameter of the inferior vena cava is measured in its distended state with a sterile centimeter rule. The smallest
Quantifying the meanings of words
Authors: W. O. Robertson
Journal: JAMA (1983)

Whether in talking with each other, interacting with patients, teaching students, or writing reports, precision in communication is always desirable. Certainly as issues of "informed consent" have emerged—first on the medical practice scene and now on the medical research scene— care and carefulness in communication seem to be capturing more attention daily. The past several years have seen a variety of programs initiated to alleviate communication difficulties between physicians, between physicians and patients, between computers and users, and among various health professionals. The success of such efforts will always depend on consistent interpretation of the words used. In 1980, Bryant and Norman,<sup>1</sup>concerned about physician-to-physician communication through laboratory and x-ray reports, selected 30 terms used frequently in those reports—such as "probably," "sometimes," and "unlikely"—which seemed subject to repeated misinterpretations or to differences in interpretations by different physicians. They asked a group of hospital-based Canadian physicians to specify on a
Cadmium-Binding Proteins in the Mussel, Mytilus edulis
Authors: John M. Frazier
Journal: Environmental Health Perspectives (1986)

Inducible cadmium-binding proteins (Cd-BP) in the mussel, Mytilu edulis, were resolved into two mo- lecular weight components, designated Cd-BP,o and Cd-BP20, by gel-permeation chromatography on Seph- adex G-75.Each of these two molecular weight components were further resolved into four subcomponents by DEAE-ion-exchange chromatography.All eight subcomponents bound cadmium and exhibited significant UV absorption at 254 nm and little absorption at 280 nm.Each subcomponent was purified and subjected to amino acid composition analysis.Two classes were identified, one having higher cysteine (23.9-26.6 mole- %) and lower glutamic acid contents compared to the other class (11.6-18.2mole-% cysteine).All subcom- ponents have a relatively high glycine content (approximately 15 mole-%) relative to mammalian metallothioneins (approximately 8 mole-%).Although the Cd-BP20 have apparent molecular weights almost twice the Cd-BP,O, the exact molecular relationship between these binding proteins is not known.
Hubris and Nemesis in heads of government
Authors: R. L Leon
Journal: Journal of the Royal Society of Medicine (2007)

By couching the discussion of Blair and Bush in terms of hubris and nemesis, Lord Owen 1 has avoided the pitfall of diagnosis from afar while still highlighting serious problems with the two world leaders (JRSM November 2006).He does dip his toe into psychodynamics citing Freud and Justin Frank, but, by and large, he sticks to discussing behaviour and its relation to hubris and power.As a politician, Lord Owen is qualified to discuss the political leaders he has encountered.As a physician, should he be making medical judgments on political leaders?Simon Wessely has questions about this and about whether or not psychiatrists should venture beyond the consulting room. 2 Should psychiatrists limit their judgments to patients they have examined?The American Psychiatric Association says 'yes' and Dr Wessely cites data to support that view.But the question remains, can psychiatrists and neuroscientists, with the help of philosophers, provide useful insights that contribute to the understanding of leaders and their followers?I believe that we should try.We should bring whatever scientific data there may be to counter ideology, blind faith and the intoxicating effects of power.It is true hubris often comes with power.Even though we do not have a psychiatric diagnosis for hubris, it is a psychological entity and as such should potentially be understood by science, as are other psychological phenomena.We do not diagnose those that we have not personally examined and we cannot diagnose an entire population, but perhaps we can bring clinical and scientific insights to help understand destructive behaviour As scientists and clinicians, we too must guard against hubris.Hopefully our colleagues will help us with that.JRMS should be applauded for exploring the issue.
Re: Prasanna Sooriakumaran, Abhishek Srivastava, Shahrokh F. Shariat, et al. A Multinational, Multi-institutional Study Comparing Positive Surgical Margin Rates Among 22 393 Open, Laparoscopic, and Robot-assisted Radical Prostatectomy Patients. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2013.11.018
Authors: Gianluca Giannarini, Nazareno Suardi, Alberto Briganti
Journal: European Urology (2014)
BOOK REVIEW
Authors: M. O. THOMPSON
Journal: JNCI Journal of the National Cancer Institute (1995)

BOOK REVIEW Get access Breast Implants: Everything You Need to Know, 2nd Revised Edition Nancy Bruning . Alameda, CA : Hunter House , 1995 . 202 pp., illus. $21.95. ISBN 0-89793-176-0 MERLE O'ROURKE THOMPSON, PH.D. MERLE O'ROURKE THOMPSON, PH.D. 6012 Morgan Ct. Alexandria, VA 22312 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 87, Issue 20, 18 October 1995, Pages 1554–1555, https://doi.org/10.1093/jnci/87.20.1554 Published: 18 October 1995
Acute Intermittent Porphyria
Authors: George H. Sack
Journal: JAMA (1990)

<h3>CASE PRESENTATION</h3> Vincent J. Pompili, MD A 24-YEAR-OLD white woman was known to have acute intermittent porphyria (AIP). She completed a normal pregnancy and delivery 16 weeks ago; 14 weeks later, 2 weeks prior to admission to the hospital, she stopped breast-feeding. On the day before admission she had the acute onset of neck, back, and arm pain and weakness. These symptoms worsened over 18 hours, accompanied by nausea, vomiting, and shortness of breath. Breathing became more difficult and respiratory muscle weakness developed. She was intubated, given assisted respiratory ventilation, and admitted to the hospital. Her medical history is notable for three attacks of AIP with abdominal pain and vomiting. She took no medications. There were no known Swedish relatives, but her maternal grandfather, a maternal aunt, and her mother had AIP. On admission she was lethargic but oriented. Her vital signs were as follows: blood pressure, 120/70 mm Hg;
Are universal precautions effective in reducing the number of occupational exposures among health care workers? A prospective study of physicians on a medical service
Authors: E. S. Wong
Journal: JAMA (1991)

Using a daily questionnaire, we prospectively studied 277 physicians from two hospital medical services for incidents of exposure to blood and body fluids and barrier use before and after the implementation of universal precautions. We found that implementation significantly increased the frequency of barrier use during exposure incidents from 54% before implementation to 73% after implementation of universal precautions. Implementation led to a decrease in the number of exposure incidents that resulted in direct contact with blood and body fluids (actual exposures), from 5.07 to 2.66 exposures per physician per patient care month, and to an increase in averted exposures in which direct contact was prevented by the use of barrier devices, from 3.41 exposures per patient care month before implementation to 5.90 exposures per patient care month after implementation. Implementation affected neither the types of body fluid or procedures involved nor the overall rate of exposure incidents (8.5 per patient care month) but, through an increase in barrier use, it<i>did</i>prevent direct contact with blood and body fluids and thus converted what would have been an actual exposure into an averted one. We conclude that universal precautions were effective in reducing the risk of occupational exposures among physicians on a medical service. (<i>JAMA</i>. 1991;265:1123-1128)
Transactions of the American Microscopical Society, at its nineteenth annual meeting, held at Carnegie Library, Pittsburg, Pa., Aug. 18, 19 and 20, 1896.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Report From the Advisory Committee on Immunization Practices (ACIP): Decision Not to Recommend Routine Vaccination of All Children Aged 2-10 Years With Quadrivalent Meningococcal Conjugate Vaccine (MCV4)
Journal: JAMA (2008)

At its February 2008 meeting, the Advisory Committee on Immunization Practices (ACIP) decided not to recommend routine vaccination of children aged 2-10 years against meningococcal disease unless the child is at increased risk for the disease. This report summarizes the deliberations of ACIP and the rationale for its decision and restates existing recommendations for meningococcal vaccination among children aged 2-10 years at increased risk for meningococcal disease. ACIP continues to recommend routine vaccination against meningococcal disease for all persons aged 11-18 years and those persons aged 2-55 years who are at increased risk for meningococcal disease.
Blockade of IL-23 Signaling Results in Targeted Protection of the Colon and Allows for Separation of Graft Versus Host and Graft Versus Leukemia Effects.
Authors: Rupali Das, Richard Komorowski, Martin Hessner, Hariharan Subramaniam, Daniel J Cua, Claudia Huettner, William R. Drobyski
Journal: Blood (2009)
Perforating plate-like osteoma cutis in a man with solitary morphoea profunda
Authors: SUNG KU AHN, JIN HYOUNG WON, EUNG HO CHOI, SOO CHAN KIM, SEUNG HUN LEE
Journal: British Journal of Dermatology (1996)

Solitary morphoea profunda is an unusual form of scleroderma. characterized by marked fibrosis, hyalinization of collagen fibres, and inflammatory cell infiltration in the deep dermal and subcutaneous layers. We describe a 58‐year‐old man showing solitary morphoea profunda. Plate‐like osteoma cutis, with transepidermal elimination of bony material. within the morphoea profunda, was present.
THE DIAGNOSTIC SIGNIFICANCE OF BENCE-JONES ALBUMOSURIA.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ACHYLIA GASTRICA
Authors: JOSEPH SAILER
Journal: JAMA (1922)

Achylia gastrica was first described by Fenwick<sup>1</sup>in 1877. He then reported four cases that were undoubtedly progressive pernicious anemia characterized by a yellow discoloration of the skin, the absence of free hydrochloric acid in the gastric contents, the probable absence of ferments in the gastric contents as indicated by the undigested condition of the food, and a rapidly progressive and fatal course. He called these cases atrophy of the gastric mucous membrane. Quincke, Jaworski<sup>2</sup>and others studied the condition at the same time. The literature is considerable; but, on the whole, it cannot be said that achylia gastrica has excited any great degree of attention on the part of the medical profession. This has been largely due to the fact that it is often merely a complication of certain other conditions, such as carcinoma, progressive pernicious anemia and amyloid disease, and that very often it may exist
Multifactorial etiology of disease
Authors: J. L. Coulehan
Journal: JAMA (1979)

<h3>To the Editor.—</h3> Lest the medical profession (and other health workers) be seduced into a tranquil venture of international service, I would like to bring some reality to the correspondence of Charles Failmezger, MD, "On Volunteer Physicians in the Developing Nations" (241:132, 1979). He encourages short-term rotations (which in his case become even more abbreviated, with an average of less than two months spent in each country) while at the same time advising extensive prior preparations that he does not seem to include in his length of duty. I have been working for nearly 18 months in the same urban region of northeast Brazil, and even with on-site language training and experiences concerning local customs, I am just now at the periphery of understanding the people and environs here. The language problems should not be minimized. Whereas one may learn common expressions that help basic survival, involvement at a university