tbuckley/cabot-search huggingface dataset:
How well is interdependent care managed across specialties in breast cancer? Metrics and pre-implementation data from the 4R in Oncology Project.
Authors: Christine B. Weldon, Julia Rachel Trosman, Claudia B. Perez, Swati Kulkarni, Seema Ahsan Khan, Nora Hansen, Valerie Nelson, Jennifer Stein, Melissa A. Simon, Jonathan Blake Strauss, Al Bowen Benson, Sasa M. Espino, Mikele Bunce, Wayne Pan, Sarah M. Friedewald, William John Gradishar
Journal: Journal of Clinical Oncology (2017)

e12067 Background: The “NCI ASCO Teams” Project emphasized management of interdependent cancer care across specialties as crucial to teamwork, yet a considerable challenge (Taplin JOP 2015). Interdependent care requires well-managed timing and sequencing of events across specialties. We developed the 4R model (Right Information / Care / Patient / Time) to manage interdependent care and facilitate teamwork (Trosman JOP 2016). 4R is being implemented at 3 centers: academic, community and safety net. Pre-implementation, we identified guideline recommended interdependent care whose timing / sequencing is challenging, developed relevant adherence metrics and gathered current state data. Methods: Interviews with 42 clinicians across breast cancer (BC) specialties at the 3 sites, using theme analysis to identify challenging interdependent care. Guidelines and literature were used to define adherence metrics. Clinical data were reviewed for 216 Stage I-III patients at 3 sites to measure adherence. Results: We identified 7 BC interdependent care events for which timing / sequencing is a challenge - Table. Adherence ranged from 0% to 100%, and was &lt; 50% for 5 of the 7 care events. Preoperative BRCA 1/2 results and neoadjuvant consult showed highest adherence, yet were most frequently noted as a challenge: interviewees reported substantial ad-hoc efforts applied to managing timeliness of these events. Conclusions: Identified challenges and adherence gaps support the need for the 4R implementation for systematic, consistent and timely delivery of interdependent care. Established metrics will allow pre / post 4R implementation comparison and may inform broader adoption of the 4R model. [Table: see text]
THE HOSPITAL LABORATORY.
Journal: JAMA (2008)

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Commentaire de travail de Y. N. Lee et al., pp.819
Journal: Endoscopy (2012)

See also: Direct peroral cholangioscopy using an ultraslim upper endoscope for management of residual stones after mechanical lithotripsy for retained common bile duct stonesEndoscopy 2012; 44(09): 819-824DOI: 10.1055/s-0032-1309880
Leads from the MMWR
Journal: JAMA (1983)

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Ventricular Septal Defect with Aortic Insufficiency: Clinical and Hemodynamic Study of 18 Proved Cases
Journal: JAMA (1963)

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New Books
Journal: JAMA (1962)

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Observations during hypervolemic hemodilution of patients with acute focal cerebral ischemia
Authors: J. H. Wood
Journal: JAMA (1982)

Infusions of 5% albumin and/or dextran 40 in nine patients with acute ischemic neurological deficits reduced mean hematocrit values from 41% to 32%, raised mean central venous pressure from 4 to 12 cm H<sub>2</sub>O, and reduced mean arterial BP from 101 to 94 mm Hg. Six alert patients had ischemic structural damage on cranial computed tomography. All six alert patients with upper arm paresis objectively improved and two others with only dysphasia also improved within 24 hours after infusion initiation. Although the improvement in two patients seemed to be temporarily dependent on the continuing of the infusion, all eight alert patients were eventually weaned without loss of regained function. This report of neurological improvement during hypervolemic hemodilution suggests that augmentation of collateral perfusion secondary to reduced blood viscosity may rapidly relieve cerebral ischemia, impede infarction, and allow time for compensatory mechanisms to maintain blood flow above ischemic thresholds. (<i>JAMA</i>1982;248:2999-3004)
Rheumatic pneumonia
Authors: L R Saraiva
Journal: Annals of the Rheumatic Diseases (2002)

Guidelines for the treatment of osteoarthritisGuidelines for the treatment of osteoarthritis (OA) have several purposes, but a major one relates to its use by regulatory or medical insurance agencies that use it to help guide their response to requests for drugs to treat patients.Data have recently been published which record the efficacy of non-steroidal antiinflammatory drugs (NSAIDs) over paracetamol (acetaminophen) and report patients' preferences for NSAIDs rather than paracetamol in the treatment of OA. [1][2][3][4][5][6][7] Furthermore, inflammation is a common accompaniment of moderate to severe OA. [8][9][10] Therefore it would seem appropriate to consider the use of NSAIDs as the primary treatment in the group of patients with OA with moderate to severe pain or inflammation as part of their disease.The EULAR Guidelines state that paracetamol is the first line of treatment for all patients with OA, 11 despite the recent evidence that NSAIDs are more efficacious than paracetamol and that paracetamol is associated with more gastrointestinal toxicity than was previously thought. 12ould it not be more appropriate to suggest that patients who have moderate to severe pain and/or OA with inflammatory components be given NSAIDs as the first line of treatment, leaving paracetamol for symptomatic use in those patients with lesser degrees of pain or lack of overt inflammation?
The Boudoir Companion.
Journal: JAMA (1901)

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ANNUAL ADDRESS.
Authors: AUSTIN FLINT
Journal: JAMA (1884)

The American Medical Association has reached an age when the thoughts of one whose retrospections extend to its birth, naturally revert to the natal period of its existence. Of those who coöperated in the formation of the Association, not many now remain, and after a few more annual meetings all will have passed away. Thirty-eight years ago, a medical convention was held in the city of New York, in compliance with a recommendation by the Medical Society of the State of New York, in 1845. In 1839, the Medical Society of the State of New York adopted a resolution recommending a national convention to be held in Philadelphia in 1840. This action of the society was without effect. In connection with the recommendatory resolution adopted in 1845, a committee of three was appointed to carry the resolution into effect, and the mover of the resolution, Dr. N. S. Davis, was
Hypothesis Regarding Possible Role of Anabolic Steroid Hormones as Promoters of Neoplasia of Bone and Bone Marrow at Adolescence
Journal: JAMA (1963)

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In This Issue
Journal: Arthritis & Rheumatology (2020)

Between Extracellular Matrix Genes and Circadian Rhythm Genes and Osteoarthritis Osteoarthritis (OA) is the most common agerelated joint disease.Previous research has demonstrated that FoxO transcription factors regulate cartilage homeostasis and perform chondroprotective actions.As individuals age, the expression of FoxO transcription factors is reduced.This is also the case for individuals with OA, in that patients with OA have dysregulated FoxO pathways.In this issue, Duffy et al (p.1514) publish the results of their effort to elucidate the molecular mechanisms by which FoxO1 protects chondrocytes.They identifi ed the genome-wide occupancy profi le of FoxO1 and report that FoxO1 uses different mechanisms to regulate ubiquitous and cartilage-specifi c genes in chondrocytes.
AMA-RPS Annual Meeting Actions
Journal: JAMA (1990)

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Serum levels of miR-34a to rule-out NAFLD in healthy subjects and identify NAFLD patients with active NASH (NAS&gt;= 4) and significant liver fibrosis (F &gt;= 2)
Authors: Stephen Harrison, Quentin Anstee, Vlad Ratziu, Pierre Bedossa, Genevieve Cordonnier, Zouher Majd, Alice Roudot, Fouad Ben Sudrick, Noémie Dam, John Brozek, Pascal Birman, Pierre Chaumat, Bart Staels, Dean Hum, Suneil Hosmane, Remy Hanf, Arun Sanyal
Journal: Journal of Hepatology (2020)
Protective effect of breast milk against pneumonia is greatest for young infants
Journal: BMJ (1999)

Alcohol misusers reduce risks of surgery if they stop drinkingDuring recent years several studies have shown that alcohol misusers who drink at least five drinks a day have increased postoperative morbidity.On p 1311 Tønnesen et al report the results of the first randomised study of an intervention to reduce this morbidity-that is, one month of abstinence from alcohol (controlled with disulfiram) before surgery for colorectal resection.They found that the intervention group experienced a reduced rate of complications after the operation, possible because of improved organ function and reduced responses to surgical stress.The authors recommend preoperative assessment of alcohol misuse and withdrawal for one month before operation.
AIDS Among Racial/Ethnic Minorities—US, 1993
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Benzene Induces a Dose-Responsive Increase in the Frequency of Micronucleated Cells in Rat Zymbal Glands
Authors: Frank A. Angelosanto, Gary R. Blackburn, Ceinwen A. Schreiner, Carl R. Mackerer
Journal: Environmental Health Perspectives (1996)

The Zymbal gland, a sebaceous tissue associated with the ear duct of certain rodent species, is a principal target for carcinogenesis by benzene.To investigate the mechanism of induction of tumors in the rat Zymbal gland, we have developed a procedure for primary culture of epithelial cells from Zymbal gland explants so that cytogenetic analysis can be performed on this target tissue following an in vivo exposure to benzene.Cytogenetic analysis performed 45 hr after in vivo oral dosing with benzene revealed chromosome damage that occurred as a result of acute, subchronic, and chronic dosing.This damage, expressed as a dose-related increase in the frequency of micronucleated cells, was observed in Sprague-Dawley female rats over a range of benzene doses from 12.5 to 250 mg/kg/day, and in male Fischer 344 rats at doses ranging from 1 to 200 mg/kg/day.These results are consistent with the known clastogenicity of benzene in mouse bone marrow, which is also a target tissue.This study is the first report of a genotoxic effect of benzene in the rat Zymbal gland and shows that micronucleus formation may be used as a correlate for carcinogenesis induced by benzene in this target tissue.
Treating Adolescent Mental Health Problems Without Medication
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Novel VWF Sequence Variations Identified in Normal Controls and Index Cases Enrolled in the TS Zimmerman Program for the Molecular and Clinical Biology of VWD (ZPMCB-VWD).
Authors: Daniel B. Bellissimo, P.A. Christopherson, S.L. Haberichter, V.H. Flood, J.C. Gill, K.D. Friedman, T.C. Abshire, J.A. DiPaola, W.K. Hoots, C. Leissinger, J.M. Lusher, M.V. Ragni, A.D. Shapiro, R.R. Montgomery
Journal: Blood (2007)
Osler
Authors: Stephen B. Greenberg
Journal: JAMA (2005)

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