tbuckley/cabot-search huggingface dataset:
Lead Exposure at an Early Age Substantially Increases Lead Retention in the Rat
Authors: Shenggao Han, Xianwen Qiao, Francis W. Kemp, John D. Bogden
Journal: Environmental Health Perspectives (1997)

It has been hypothesized that the high rate of bone remodeling during childhood and the consequent high calcium and lead turnover result in a substantial reduction in bone lead stores so that much of the lead incorporated in bone during childhood does not persist into adulthood. We studied the effect of age at lead exposure on blood and organ concentrations of lead, calcium, and zinc 1-5 months after termination of lead ingestion. Blood and organ lead concentrations and contents 4 weeks after lead exposure ceased were significantly higher in the rats exposed beginning at 5 weeks of age than in those exposed beginning at 10 or 15 weeks old. Bone lead declined as the time since exposure increased. Despite this trend, the rats exposed when youngest had bone lead concentrations at 20 weeks after the termination of lead exposure that were higher than those of the other rats only 4 weeks after cessation of lead ingestion. Multiple regression analysis demonstrated that age at lead exposure remained a significant predictor of blood and organ lead concentrations and contents even after the inclusion of total lead consumed, body weight, and age at organ harvesting in the regression analysis. There were only small differences in organ calcium and zinc concentrations among treatment groups except for kidney calcium. The results do not support the hypothesis of rapid depletion of bone lead stores in young animals, but rather suggest that younger age at lead exposure is associated with greater lead retention and toxicity even in the absence of continued lead exposure.
Obstetrical Nursing.
Journal: JAMA (1891)

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Event Rates in Trials of Patients With Type 2 Diabetes
Authors: David Preiss
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prolonged remissions in acute myelocytic leukemia in adults
Authors: V. F. Fairbanks
Journal: JAMA (1968)

Three adult patients with acute myelocytic leukemia have been observed with complete remissions lasting from 2 1/2 to 9 1/2 years. Maintenance chemotherapy was not required during the period of remission. During the time in which these patients were treated initially, there were 177 other adults with acute myelocytic leukemia. Eight of these had complete remissions of six months' duration or less. No clinical, laboratory, or therapeutic differences distinguished those patients who experienced remission from those who did not. The infrequency of remission in patients above the age of 45 was confirmed. Five patients were observed to have relatively prolonged survival despite the failure of therapy to induce remission of clinically indolent, "smoldering" leukemia which was acute on morphologic grounds. Mechanisms as yet unrecognized, and possibly inherent in the host, may have been predominant in determining the course and prognosis.
Histone Deacetylase Inhibitors Demonstrate Significant Preclinical Activity as Single Agents, and in Combination with Bortezomib in Waldenstrom's Macroglobulinemia.
Authors: Jenny Sun, Lian Xu, Hsiuyi Tseng, Bryan Ciccarelli, Mariateresa Fulciniti, Zachary Hunter, Kaveh Maghsoudi, Evdoxia Hatjiharissi, Yangsheng Zhou, Guang Yang, B. Zhu, Xia Liu, Ping Gong, Thea Ioakimidis, Patricia Sheehy, Robert Manning, Christina Hanzis, Megan Lewicki, Christopher J Patterson, Dharminder Chauhan, Scott J. Rodig, Nikhil C. Munshi, Kenneth. C Anderson, Owen O O'Connor, Steven Treon
Journal: Blood (2009)
RESPIRATORY GYMNASTICS IN PULMONARY TUBERCULOSIS.
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Incorrect Wording in Quotation.
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
CONTRIBUTIONS OF PHARMACOLOGY TO PHYSIOLOGY.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Allergy
Journal: JAMA (1998)

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More on Obesity, Cholesterol, Hypertension and Coronaries
Journal: JAMA (1962)

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Observer variation in recording clinical data from women presenting with breast lesions. Report from the Yorkshire Breast Cancer Group.
Journal: BMJ (1977)

The degree of observer variation in recording 11 186 items of clinical data from 242 woman who presented complaining of a lump in the breast to a group of 10 surgeons was studied. Each women was interviewed and examined twice and the findings (of the two clinicians) compared. There was a wide range of variation among the observers. Variation in recording the presence or absence of axillary nodes was considerable (45%), as was that in sizing the primary lesion (55%). In 20% of cases the two assessments of primary lesion size differed by over 2 cm. In other respects the results were more encouraging; much variation could be eliminated by wording the proforma more clearly. Moreover, variation was not person-specific, so that these findings are probably reasonably representative. Any future trial of breast lesions should (a) design specific proformata, (b) define terminology, (c) make these definitions universally available, and (d) conduct observer variation studies before the start of the full trial.
Pediatrics
Journal: JAMA (1999)

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HUMAN BEINGS AND THE PARASITE OF TEXAS CATTLE FEVER.
Journal: JAMA (1904)

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Massachusetts Medical Society
Authors: Basil E. Barton
Journal: New England Journal of Medicine (1962)

DEATHSDolan — William F. Dolan, M.D., of Winchester, died on July 11. He was in his seventy-second year.Dr. Dolan received his degree from Harvard Medical School in 1913. He was a staff physician at St. Elizabeth's and Winchester hospitals and was a member of the American Medical Association, a fellow of the American College of Surgeons and a senior member of the Massachusetts Medical Society.He is survived by two sons, three daughters and a sister.Hampson — Nishan M. Hampson, M.D., of Watertown, died on July 3. He was in his eightieth year.Dr. Hampson received his . . .
CONCEALED ALCOHOL IN DRUGS.
Authors: T. D. CROTHERS
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Proceedings of the Thoracic Society
Journal: Thorax (1962)

composed of several symposia and two short papers.Summaries follow.SYMPOSIUM ON SARCOIDOSIS INCIDENCE D. G. JAMES said that the incidence of suspected sarcoidosis, detected by mass radiography surveys, is approximately 20 per 100,000 population in England and Wales.Its frequency is about one-tenth that of active pulmonary tuberculosis.The incidence appears to be similar in various parts of Britain; there are no peaks of undue prevalence.The incidence of sarcoidosis is similar in men and women at all ages, but it is twice as common (40 per 100,000) in women of the childbearing years of life.It was extremely common in Irish women (220 per 100,000) and Irish men (110 per 100,000) radiographed in London.Factors influencing the incidence of sarcoidosis include diagnostic criteria, age, sex, and race.There may also be regional factors which possibly account for peaks of prevalence in certain regions of various countries.These factors and zones were analysed.In future epidemiological studies, which include mass radiography surveys and Kveim-testing programmes, a plea was made to collect and store sera from patients with sarcoidosis, for they may well be the source of important data. PRECIPITINS AGAINST MYCOBACTERIAL ANDOTHER EXTRACTS IN SARCOIDOSIS J. PEPYs reported that the sera of patients with sarcoidosis had been tested and compared with (1) sera of tuberculous and apparently normal subjects and (2) sera of patients with farmer's lung, because of the radiographic and histological similarities.(1) Precipitins against extracts of photo-, scotoand non-chromogenic mycobacteria had been found in almost all sera from patients with sarcoidosis (from British patients and from patients in Madison, Wisconsin, U.S.A.), in almost all sera from tuberculous and apparently normal subjects, including cord-blood sera of infants of normal mothers.These maternal precipitins seem to disappear in early infancy.No difference in the pattern of reactions was found in patients with or without sarcoidosis.(2) Precipitins against extracts of mouldy hay were found in 32% of sera from patients with sarcoidosis as against 7% of that from normal subjects and 81% of that from patients with farmer's lung.These precipitins appear to be against a component of the hay itself rather than against its fungal components.
BOOKS RECEIVED.
Journal: JAMA (1883)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A report of fluorosis in the United States secondary to drinking well water
Authors: A J Felsenfeld, M A Roberts
Journal: JAMA (1991)

A 54-year-old female resident of Wellston, Okla, was found to have osteosclerosis on a routine chest roentgenogram. Subsequent investigation disclosed the cause of her osteosclerosis to be fluorosis secondary to the ingestion of well water containing 429 mumol/L of fluoride (recommended levels, 11 to 58 mumol/L). Water samples were also obtained from the 12 wells on properties adjacent to the index case. In three other wells, all at similar depths as the well of the index case, the fluoride concentration of the water was greater than 212 mumol/L. Urine samples from members of the four households who obtain their drinking water from these wells contained elevated urinary fluoride levels. Thus, fluorosis may develop in certain areas of the United States as a result of the natural occurrence of fluoride in the groundwater. Consequently, in known endemic areas, it would appear reasonable to measure the fluoride concentration of the well water at the time of drilling.
Fertility and Sterility, New York
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal