tbuckley/cabot-search huggingface dataset:
Farming from a New Perspective: Remote Sensing Comes down to Earth
Authors: W. Conard Holton
Journal: Environmental Health Perspectives (2000)

Farmers strive to increase the yield of their fields by adding nutrients and water to the land, and using pesticides to control insects and disease. In addition to bountiful harvests, the results of their endeavors may include elevated amounts of fertilizers in surface waters and aquifers and potential risk to themselves and their neighbors from exposure to pesticides. Precision agriculture is the use of modern information technologies such as geographic information systems, the global positioning system, and remote sensing from the air to reduce the environmental effects of these chemicals while enhancing the productivity of farming. By combining crop yield maps with soil survey maps and remote sensing output, farmers can identify areas that need more or less fertilizer, water, or pesticide.
Systemic vasculitis with coexistent large and small vessel involvement. A classification dilemma
Authors: R. D. deShazo
Journal: JAMA (1977)

A patient with systemic vasculitis had the palpable purpuric lower extremity lesions of leukocytoclastic vasculitis and the renal aneurysms of polyarteritis nodosa, features thought to clearly separate these two syndromes. Questions are raised pertinent to the classification, diagnosis, treatment, and prognosis of systemic vasculitis. (<i>JAMA</i>238:1940-1942, 1977)
Smoke in the Air
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Comparative Developmental Aspects of Selected Organ Systems. II. Gastrointestinal and Urogenital Systems
Authors: Richard M. Hoar
Journal: Environmental Health Perspectives (1976)

A brief description of the basic patterns of mammalian organogenesis of the gastrointestinal and urogenital systems is presented based on events as they occur in human beings. The emphasis is not on the details of this development, but rather on its organization and timing, with tables of comparative development providing a comparison of similar events in man, rat, mouse, and chick.
An outbreak of Mycoplasma pneumoniae infection in a nuclear submarine
Authors: R. Sawyer
Journal: JAMA (1966)

A NUMBER OF STUDIES have drawn attention recently to the association between acute respiratory infections and the presence in the respiratory tract of<i>Mycoplasma pneumoniae</i>in civilian<sup>1,2</sup>and in military populations.<sup>3,4</sup>The symptomatology has varied from a mild illness, resembling the common cold, through severe and deep-seated pneumonitis with pronounced constitutional upset. We recently had the opportunity to study an outbreak of respiratory illness due to this agent which occurred among the crew members of a nuclear submarine on patrol, and, as many of the features were of unusual interest, we describe them here. <h3>Outbreak</h3> This occurred on board a fleet ballistic-missile submarine operating from Holy Loch, Scotland. The crew is based in New London, Conn and flies to Scotland three weeks before deployment on patrol. Each patrol lasts eight weeks and the crew is continuously isolated from the surface atmosphere for seven of these weeks. During this
Teaching CPR
Authors: Cortney Davis
Journal: Annals of Internal Medicine (1996)

Ad Libitum1 November 1996Teaching CPRCortney Davis, MA, ANPCortney Davis, MA, ANPRedding, CT 06896.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-125-9-199611010-00011 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail First, shake the shoulders, shout Annie, Annie!Are you OK?The mannequins are named for a girl who drowned;her parentshad her likeness made—blue sweats, white sneakers,blond latex hair.If there's no response, tip back the chin, place your cheeknear the lips.Look for the breast to rise, listen for a rush of air, feelmoist breezeagainst your cheek. If you don't, seal your lips aroundthe mouth,fingers pinch the nose. Big breath in, and blow. It feels,in real life,or should I say real death, as if lungs are sponge, breathis water.... Author, Article, and Disclosure InformationAffiliations: Redding, CT 06896.Corresponding Author: Cortney Davis, MA, ANP, PO Box 678, Redding, CT 06896. Previousarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 November 1996Volume 125, Issue 9Page: 769KeywordsCardiopulmonary resuscitationCarotid arteriesHeart rateLatexLungsMouthShouldersSweat Issue Published: 1 November 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
BILHARZIA DISEASE IN NATAL: ITS PREVALENCE AND TREATMENT
Journal: JAMA (1921)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prevalence of Recommended Levels of Physical Activity Among Women—Behavioral Risk Factor Surveillance System, 1992
Journal: JAMA (1995)

Regular physical activity provides important health benefits for women, including lower risks for coronary heart disease, some cancers, osteoporosis, and other leading causes of death and disability (1-3). Despite such benefits, the proportion of women in the United States reporting regular physical activity has been low (4). Because even moderately intense physical activity has substantial health benefits, public health recommendations for physical activity have been expanded to a broader spectrum of activity, including gardening, walking, and housework in addition to more vigorous aerobic exercise (e.g., jogging) (5,6). To improve estimates of the prevalence of participation in physical activity at levels associated with health benefits among adult women, data about leisure-time physical activity were analyzed from the 1992 Behavioral Risk Factor Surveillance System (BRFSS). This report summarizes the results of these analyses.(ABSTRACT TRUNCATED AT 250 WORDS)
Essays on Bacteriology and the Relation to the Progress of Medicine.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
VITAMIN THEORIES
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Assisted Circulation: II. Effects of Counterpulsation on Left Ventricular Oxygen Consumption and Hemodynamics
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Monitoring for Side Effects of NSAIDs-Reply
Authors: George R. Gay
Journal: JAMA (1991)

<h3>In Reply.—</h3> Dr Graham objects to my suggestion of "careful and serial" monitoring of liver functions, suggesting that this wording places an unnecessary burden on the prescribing physician and indeed may make him or her more liable to litigation. As part of my conclusion, I stated, "We would be well advised, then, to monitor liver functions (especially the transaminases) carefully and serially in any patient undergoing long-term NSAID therapy." I further recommended baseline liver profile studies in any individual suspected to be at risk for hepatic injury (as briefly outlined, alcohol or other drug abusers, those debilitated or immunocompromised, those testing positive for the human immunodeficiency virus or at risk for the acquired immunodeficiency virus, those with a history of foreign travel, those exposed to toxic industrial products or hepatitis, those receiving blood transfusions, or those with a "chronic pain" problem with attendant "overmedication," either "self" or iatrogenic. Dr Graham
Genitourinary Tuberculosis
Authors: P. Konstam
Journal: BMJ (1971)

BACKGROUND--Previous work has indicated a high rate of non-attendance at hospital based clinics among young, multiracial asthmatic patients of lower socioeconomic class. The efficacy of delivering asthma education from a community health centre established in a multiracial working class neighbourhood was evaluated. METHODS--A prospective controlled study was performed in which asthmatic subjects aged between two and 55 years attending a hospital emergency room with acute asthma and living within a defined geographical area of high emergency room users were randomised to the usual follow up or the education centre plus usual follow up. Measurements were taken at entry into the study and again nine months later. RESULTS--At nine months patients randomised to the education centre had more preventive medications, more peak expiratory flow meters and better flow meter technique, more self-management plans, better knowledge of appropriate action to take when confronted with worsening asthma, less nocturnal awakening, and better self-reported asthma control than the control group. There was no difference between the study groups in measurements of compliance, hospital admission, days lost from school or work, or emergency room use. CONCLUSIONS--The main effects of education were on asthma knowledge and self-management skills, whilst improvements in asthma morbidity were small. Potential reasons for this include heterogeneous study population (in terms of baseline self-management skills, asthma severity, ethnicity and age), pragmatic study design, insensitivity of many of the measurements of morbidity, the modest effectiveness of a single time limited education programme, and inability to limit the effects of such a large community based study to the intervention group (there was a 67% reduction in asthma admissions during the study period from the geographical area targeted compared with a 22% reduction for the rest of Auckland).
Fracture of the femoral neck in a child
Authors: J. E. Butler
Journal: JAMA (1971)

Dr. Butler: The patient is a 10-year-old girl who fell out of a tree. She experienced immediate pain in the right hip, but there were no other complaints. She was taken to the emergency room where a complete examination failed to disclose injury other than the fracture of the right femoral neck shown in Fig 1. The nervous and circulatory systems in the involved extremity were normal. We are privileged today to have the assistant director of the Newington (Conn) Children's Hospital to discuss this difficult problem. <h3>Discussion</h3> Dr. Cary: The injury demonstrated is a displaced fracture of the base of the neck of the femur in a 10-year-old girl. In view of the reported high incidence of complications of fracture healing, growth disturbance and vascular impairment of the proximal fragment, this must be considered a difficult fracture problem, with guarded prognosis. The key to understanding these difficulties, as well
SURGERY FOR AORTO-ILIAC OCCLUSIVE DISEASE
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phase I study of PF-03446962, a fully human mAb against ALK 1, a TGFβ receptor involved in tumor angiogenesis.
Authors: L. W. Goff, R. B. Cohen, J. Berlin, C. Noberasco, H. Borghaei, C. Gallo-Stampino, E. Wang, D. Hu Lowe, W. J. Levin, F. G. De Braud
Journal: Journal of Clinical Oncology (2011)

3009 Background: Transforming growth factor β (TGF β) is a cytokine able to regulate many biological processes in cancer. At vascular level, the activity of TGFβ is exerted by selectively binding to its receptor, activin receptor like kinase 1 (ALK-1), triggering a downstream signaling involving intracellular and nuclear proteins (SMADs and Id1) and leading to transcriptional upregulation of proangiogenic factors. PF-03446962 is a fully human mAb against ALK-1 with dose dependent antiangiogenic activity as demonstrated preclinically in human tumour xenografts. Mechanistic studies indicated that ALK 1 and VEGF signalling pathways may promote angiogenesis in a collaborative manner. Methods: We conducted a phase I trial in patients (pts) with solid tumors. Primary objectives: identify MTD and a recommended phase II dose (RP2D); secondary objectives included safety profile, PK, antitumor activity, soluble proteins TGFβ related and blood flow by contrast enhanced ultrasound (CE-US). Results: 41 pts have been enrolled on 8 dose levels (0.5-15 mg/kg). PF-03446962 is administered iv on Day 1, 29 and then q 2 weeks. 15 mg/kg was defined as maximum administered dose, with DLTs represented by G3 thrombocytopenia and increase in pancreatic enzymes in 2/6 pts. The dose of 6.75 mg/kg was defined as RP2D and PK data support the proposed regimen with drug concentration above the estimated therapeutic concentrations during each cycles. 2 PRs were observed, one hepatocellular carcinoma (HCC) resistant to anti-VEGF therapy and one NSCLC (still ongoing). SD lasting for at least 12 weeks was observed in 9/41 pts, with 2 patients (adrenocortical ca. and mesothelioma) still ongoing after 11 months from treatment start. 2/5 HCC pts showed a TTP of 5.5-6 months similar to those observed with sorafenib in first line. CE-US showed changes consistent with reduced blood flow in 2/3 pts assessed at this time. Conclusions: PF-03446962 is a first in class mAb anti ALK-1, safe and with manageable toxicities, mainly characterized by asymptomatic elevation of pancreatic enzymes and transient platelet decreases. Based on clinical activity, anti ALK 1 may be a promising novel antiangiogenic strategy for pts who failed anti VEGF/VEGFRTKI in clinic.
ADMINISTRATION OF ETHER BY THE USE OF A SIMPLE MECHANICAL ETHER DROPPER
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal