tbuckley/cabot-search huggingface dataset:
The Century Book for Mothers. A Practical Guide in the Rearing of Healthy Children.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
AMA-RPS Policy Promotion Grants
Journal: JAMA (1996)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Wellspring
Authors: Charles K. Morris
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Paediatric Surgery
Authors: Robert J. Touloukian
Journal: JAMA (1989)

A surgical atlas, to be successful, should clearly delineate in graphic detail how the author performs the operative procedure, special techniques that simplify the operation, and how to avoid "surgical traps" that lead to postoperative complications.<i>Rob and Smith's Operative Surgery: Paediatric Surgery</i>, fourth edition, largely accomplishes those preestablished goals. The scope and extent of the material have been enlarged in accordance with the rapid development and increasing sophistication of the specialty over the past few years. Of particular importance are the introductory chapters on transport of the neonate, preoperative and postoperative management, and anesthesia. The subsequent chapters include not only the indications for operation but also the postoperative complications and statistics on morbidity and mortality. The preoperative evaluation remains particularly sketchy, and I was disappointed to find no mention made of arterial blood gas determination in resuscitation of babies with congenital diaphragmatic hernia. The illustrations are adequate and internally
ESCAIDE 2015: registration and call for abstracts now open
Authors: Collective Eurosurveillance editorial team
Journal: Eurosurveillance (2015)

Preview this article: ESCAIDE 2015: registration and call for abstracts now open, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/eurosurveillance/20/13/art21083-en-1.gif
Nutritional Assessment
Authors: Richard A. Wright
Journal: JAMA (1980)

THE AREA of nutrition has been neglected by the medical profession. Most medical schools devote less than three hours of total instruction to nutritional deficiency and therapy.<sup>1</sup>Only 3% of all questions on parts I, II, and III of the National Boards deal with the nutritional aspects of disease.<sup>1</sup>In short, physicians in the United States are not required to have any understanding of nutrition to be licensed to practice medicine. This situation is in striking contrast with increasing evidence that a large proportion of patients in our hospitals are malnourished. In 1976, Bistrian and coworkers<sup>2</sup>conducted three single-day nutritional surveys on patients in the general medical wards of the Boston City Hospital. By standard criteria more than 44% of the patients were malnourished, and the majority had definite signs of protein-calorie malnutrition. Willcutts, who assessed patients in a private community hospital, found 33% of the patients
Reviews
Journal: BMJ (1933)

IMMUNITYthat the teaching is in any way unorthodox, but thatThe chapters on immunity in The Principles of Bacterio-in the method of its presentation it strikes an entirely logy and Immunity by Topley and Wilson were generally new note so far as a medical textbook is concerned.The accepted as a valuable exposition of the subject * now printing is in a large, clear type, the size and weight are Professor TOPLEY has extended and rewritten this convenient for the reader to hold comfortably, and the material as a separate boo'k, An Outline of Immunity.' wide margin to the page, with the many thumb-nail materials asepar book , An Outlussestheinsion of I ity, t illustrations, makes it singularly attractive to the eye, and mechanisms employed by host and invader in their dissipates that feeling of oppression which the old, closely struggle, the relative importance of the mechanisms of printed, stodgy textbook too often conjured up.The defence, the resulting degree of protection of individuals style is delightfully clear, and relieved by frequent flashes and of an infected herd, the influence of environment on of humour, the author's vigorous personality being resistance, and the ways in which we can affect the stamped on every page.In spite of the absence of formidstruggle.It would be difficult to do justice to the range able tables and classifications by numbers, not an essential and completeness of the book without going through the is lacking.The author has shown much skill in deciding what to leave out as well as what to put in.contents chapter by chapter; here it is only possible to at the ommenemetlo ac chapte a ie s mention some of the more outstanding features.
Thrombotic thrombocytopenic purpura: onset during dipyridamole therapy
Authors: J. R. Lindquist
Journal: JAMA (1981)

<h3>To the Editor.—</h3> In thrombotic thrombocytopenic purpura (TTP), increased peripheral destruction of platelets is thought to occur because of widespread deposition of fibrin within the vascular system.<sup>1</sup>This knowledge has led to the successful use of platelet inhibitors in the treatment of this condition.<sup>2</sup>We recently had the opportunity to care for a patient exhibiting the clinical features of TTP while she was taking dipyridamole for an unrelated cardiac condition. <h3>Report of a Case.—</h3> A 52-year-old woman was admitted to Mercy Hospital, San Diego, with a three-week history of weakness and easy fatigability. She was brought to the emergency room after an episode of slurred speech that had resolved over several hours. She was not aware of her elevated temperature and denied recent fever or symptoms of an infectious nature. Seven years previously, she had been given lanatoside C, 0.5 mg daily, and dipyridamole, 100 mg three times
Growing Pains?
Authors: Morse J. Shapiro
Journal: JAMA (1961)

<h3>To the Editor:—</h3> InThe Journalof Nov. 19, 1960, p. 1656, under "Questions and Answers," the reply to a question concerning "nocturnal muscular pains" in children misses the most important factor. The enclosed table from my article (Differential Diagnosis of Rheumatic and Non-Rheumatic Leg Pains,<i>Mod Conc Cardiov Dis</i><b>24</b>:296 [Oct.] 1955) indicates that these pains are very common and that they do not indicate organic disease. Such nocturnal pains occur in normal healthy children, may possibly be due to normal growth but more probably due to violent play during the previous day; massage and an aspirin tablet give almost immediate relief. The patient awakes completely relieved. Grandma may have been correct, there may be such a thing as "growing pains."
BOOK REVIEW
Authors: S. B. MURPHY
Journal: JNCI Journal of the National Cancer Institute (1993)

Journal Article BOOK REVIEW Get access Principles and Practice of Pediatric Oncology, Second Edition Philip A. Pizzo , David G. Poplack , eds. Philadelphia : J. B. Lippincott , 1993 . 1350 pp., illus. $165. 0-397-51207-4 SHARON B. MURPHY, M.D. SHARON B. MURPHY, M.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 85, Issue 21, 3 November 1993, Page 1768, https://doi.org/10.1093/jnci/85.21.1768 Published: 03 November 1993
J Air Pollut Control Assoc, Pittsburgh
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications
Authors: P. Lips
Journal: Endocrine Reviews (2001)

Vitamin D deficiency is common in the elderly, especially in the housebound and in geriatric patients. The establishment of strict diagnostic criteria is hampered by differences in assay methods for 25-hydroxyvitamin D. The synthesis of vitamin D3 in the skin under influence of UV light decreases with aging due to insufficient sunlight exposure, and a decreased functional capacity of the skin. The diet contains a minor part of the vitamin D requirement. Vitamin D deficiency in the elderly is less common in the United States than elsewhere due to the fortification of milk and use of supplements. Deficiency in vitamin D causes secondary hyperparathyroidism, high bone turnover, bone loss, mineralization defects, and hip and other fractures. Less certain consequences include myopathy and falls. A diet low in calcium may cause an increased turnover of vitamin D metabolites and thereby aggravate vitamin D deficiency. Prevention is feasible by UV light exposure, food fortification, and supplements. Vitamin D3 supplementation causes a decrease of the serum PTH concentration, a decrease of bone turnover, and an increase of bone mineral density. Vitamin D3 and calcium may decrease the incidence of hip and other peripheral fractures in nursing home residents. Vitamin D3 is recommended in housebound elderly, and it may be cost-effective in hip fracture prevention in selected risk groups.
Newly Diagnosed Heart Failure with Renal Insufficiency – Cardiac MRI-Guided Clinical Decision Making
Authors: Kana Fujikura
Journal: Clinical Cardiology and Cardiovascular Interventions (2021)

A 63 year-old female with multiple atherosclerotic risk factors presented with newly diagnosed heart failure. Clinical presentation and initial work-up studies (e.g. laboratory findings, ECG, and echocardiography) were indeterminate for ischemic or non-ischemic etiology. As she developed contrast-induced nephropathy, coronary angiography was initially deferred and cardiac MRI was performed instead. Cardiac MRI elegantly demonstrated non-ischemic cardiomyopathy that was subsequently confirmed by invasive coronary angiography. This case emphasizes the important role of cardiac MRI in establishing the etiology of cardiomyopathy, ultimately altering the clinical management of the patient with newly diagnosed heart failure.
The Dietary Fat—Breast Cancer Hypothesis Is Alive
Authors: Arthur Schatzkin
Journal: JAMA (1989)

Data from animal experiments and human correlation studies strongly support the dietary fat—breast cancer hypothesis. Moreover, a causal relation between dietary fat and breast malignancy is biologically plausible. Negative findings from recent analytic epidemiologic studies of dietary fat and breast cancer, however, have fueled the notion that the hypothesis is no longer viable. We argue that only limited conclusions should be drawn from epidemiologic studies to date because of the narrow range of dietary fat intake among subjects and the substantial measurement error in dietary assessment. Although many doubts remain about the dietary fat—breast cancer hypothesis, the question is of such importance that intensive efforts at designing better studies of the hypothesis are urgently needed. Such studies might include (1) laboratory investigations in humans that examine possible mechanisms for the effects of fat, (2) large, prospective epidemiologic studies, and (3) randomized, controlled diet trials. (<i>JAMA</i>. 1989;261:3284-3287)
Myasthenia Gravis
Authors: W. KING ENGEL
Journal: Annals of Internal Medicine (1974)

In myasthenia gravis, fatigability and persistent, often fatal weakness of voluntary muscles are attributable to dysfunction at the neuromuscular junction. The overall dysimmune state of the patient probably causes the junctional defect. Seventy percent of patients have thymic hyperplasia and 10%, thymoma. The atrophy of muscle fibers usually looks like denervation atrophy, and there are morphologic abnormalities of motor axon endings and the postsynaptic region of the muscle fiber. Electromyographic studies detect the neuromuscular junction defects: fatigue on repetitive stimulation and post-tetanic exhaustion. "Open-biopsy EMG" confirms that the commonly found electromyographic pattern comes from regions showing only denervation-like atrophy of muscle fibers. Other diagnostic tests include benefit from anticholinesterases and worsening by d-tubocurarine; the worsening of weakness by lactate infusion might serve as a diagnostic test. Treatment includes anticholinesterases, thymectomy, and the recently introduced long-term, high single dose, alternate-day prednisone program. Experienced 24-hour nursing surveillance is essential to treatment of the severely myasthenic patient.
Ethical Guidelines for Publications of Research
Journal: Endocrine Reviews (1996)

The Publications Committee has been keenly aware of the importance of formulating and disseminating rules of good conduct for authors, reviewers, and editors. Equally important is the establishment of due process for alleged or apparent improprieties. The Council of The Endocrine Society has approved the following Ethical Guidelines as prepared by the Publications Committee and has authorizeu periodic publication as well as distribution to members of our Editorial Boards, reviewers, and authors submitting manuscripts. The following statement is not meant to be all inclusive but is provided in sufficient detail to give a clear understanding of ethical considerations to all concerned.
LIVEDO RETICULARIS
Authors: CHARLES M. WILLIAMS
Journal: JAMA (1925)

Every dermatologist has observed the peculiar mottling of the skin that sometimes occurs when the body is exposed to the cold. It is so common an occurrence that no attention is paid to it, beyond noting that it is not an early macular syphilid. And yet the phenomenon is not universal—many patients show no such mottling. What is the cause of the difference? It is a question that has not yet been answered, principally because the condition is so transitory and unimportant that very few have given any study to it. The words cutis marmorata and livedo, which have been applied to this condition, are not to be found in the indexes of most of our dermatologies. Mild as it is, this rash is only the first member of a long series, gradually increasing in extent and in severity, constituting, in the more severe cases, a permanent disfigurement. There is
Lehrbuch der systematischen Anatomie.
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Peace on earth, good health for men
Authors: G. D. Lundberg
Journal: JAMA (1984)

Approximately one year ago we wrote that there was no current or impending physician glut and that the entire alleged problem of physician overabundance or underabundance was simply one of massive maldistribution on a neighborhood, city, state, regional, national, or continental basis.<sup>1</sup>We documented that there was a giant imbalance in the doctor import-export ratios and that our country's 50:1 positive balance of trade of doctors was embarrassing. We suggested that an appropriate role for a developed country to play in 1984 was to export physicians to a world in need.<sup>2</sup>The response was overwhelming. We obviously struck a very responsive cord among many physicians whose zest for doing interesting and exciting things or whose penchant for altruism was ripe. Many of you wrote us and asked what you could do and where you could go. But we didn't know, except in very general ways. So we set
A phase III randomized controlled trial of short-course radiotherapy with or without concomitant and adjuvant temozolomide in elderly patients with glioblastoma (NCIC CTG CE.6, EORTC 26062-22061, TROG 08.02, NCT00482677).
Authors: James R. Perry, Christopher J O'Callaghan, Keyue Ding, Wilson Roa, Warren P. Mason, J. Gregory Cairncross, Alba Ariela Brandes, Johan Menten, Claire Phillips, Michael F. Fay, Ryo Nishikawa, Chad Winch, Normand Laperriere
Journal: Journal of Clinical Oncology (2012)

TPS2104 Background: The EORTC (26981-22981)/NCIC CTG (CE.3) RCT in newly diagnosed GBM found improved survival with concomitant and adjuvant temozolomide (TMZ) added to radiotherapy (RT). Study pts were 18-71 (median 56) years; however a sub-group analysis noted a trend of decreasing benefit from the addition of TMZ with increasing age, such that for age 65-71, the hazard ratio of 0.8 did not reach statistical significance (p=0.340). Recent RCTs in elderly GBM found improved survival with RT compared to supportive care alone and detected non-inferiority of 40 Gy/15 vs. a 60 Gy/30 RT regimen. Based upon these results short-course hypofractionated RT is often recommended for elderly pts. However, whether the addition of TMZ to RT confers a survival advantage in elderly pts remains unanswered. Methods: Patients ≥65 yrs of age with histologically confirmed newly diagnosed glioblastoma, ECOG 0-2, are randomized 1:1 to receive 40Gy/15 RT vs. 40Gy/15 RT with 3 weeks of concomitant temozolomide plus monthly adjuvant TMZ until progression or 12 cycles. Stratification is by centre, age (65-70, 71-75, or 76+), ECOG 0,1 vs 2, and biopsy vs resection. For 90% power to detect a 25% reduction in the primary outcome of overall survival (increased MST from 6 to 8 months) between arms, using a two-sided 5% alpha, a minimum of 520 deaths must be observed prior to analysis; total sample size is 560 patients. The trial is open in Canada (NCIC CTG), Europe (EORTC), Australia and New Zealand (TROG), and Japan. As of Jan 25, 2012, 361 (65%) of the target 560 pts were randomized (147 Canada, 144 Europe, 64 Australasia, 6 Japan). Median age of randomized patients is 73 (65-88) years. A planned futility analysis after 120 events by the independent DSMB resulted in a recommendation that the trial continue.Accrual is expected to be complete in 2013. A comprehensive molecular companion analysis, including MGMT promoter methylation, is planned.
Erratum: At the Root: Defining and Halting Progression of Early Chronic Obstructive Pulmonary Disease
Authors: Israel Amirav, Claude Kasereka Masumbuko, Michael Hawkes
Journal: American Journal of Respiratory and Critical Care Medicine (2018)

As can be seen, techniques to quantify RR are imprecise and show clinically unacceptable levels of agreement, especially in children under the age of 5 years.Even direct manual counting of RR performed by well-trained personnel can be problematic.Until we have some LMIC-validated "gold" standard techniques that are better than the current "bronze" or "silver" standards, diagnostic accuracy cannot be meaningfully evaluated.There is a need to define a better reference standard for RR in children that takes into account the special settings of LMICs, where most childhood pneumonia deaths occur.