Photosensitization
Authors: HAROLD F. BLUM
Journal: Annals of Internal Medicine (1933)

Article1 January 1933PhotosensitizationHAROLD F. BLUM, Ph.D.HAROLD F. BLUM, Ph.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-6-7-877 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere are phenomena in a considerable number which are produced in living systems by substances not normally present in these systems which sensitize them to light. These phenomena are described collectively under the termphotodynamic action;they are of widespread occurrence and manifest themselves in various ways. As examples may be cited: the hemolysis of red cells and the destruction of bacteria by light and eosin, and the poisoning of domestic animals by substances ingested from buckwheat. As has been pointed out by Blum (1932), these phenomena are apparently based upon similar chemical reactions, since, so far as they have...Bibliography BARBERHOWITTKNOTT HWFDFA: Some observations on light sensitization, Guy's Hosp. Rep., 1926, lxxvi, 314-341. Google Scholar BLUM HF: Photodynamic action, Physiol. Rev., 1932, xii, 23-55. CrossrefGoogle Scholar GARROD AE: Inborn errors of metabolism, Chap. viii, Hematoporphyria congenita, 1923, Froude, and Hodder and Stoughton, London. Google Scholar GYÖRGYGOTTLIEB PK: Verstärkung der Bestrahlungstherapie der Rachitis durch orale Eosinverabreichung, Klin. Wchnschr., 1923, ii, 1302-1303. CrossrefGoogle Scholar HAUSMANN W: Grundzüge der Lichtbiologie und Lichtpathologie, Strahlentherapie, viii Sonderband, 1923, Urban and Schwarzenberg, Berlin. Google Scholar HAUSMANNHAXTHAUSEN W: Die Lichterkrankungen der Haut, Strahlentherapie, xi Sonderband, 1929, Urban and Schwarzenberg, Berlin. Google Scholar HAUSMANNKRUMPEL WO: Über die Absorption der Porphyrine im Ultraviolett, Biochem. Ztschr., 1927, clxxxvi, 203-212. Google Scholar HAUSMANNKRUMPEL WO: Über die Absorption von Farbstoffen und Leukoverbindung als Vorbedingung der photobiologischen Sensibilization im Ultraviolett, Biochem. Ztschr., 1929, ccix, 142-148. Google Scholar HAUSMANNSONNE WC: Über die sensibilisierende Wirkung des Hämatoporphyrins im Ultraviolett, Strahlentherapie, 1927, xxv, 174-182. Google Scholar JAUSIONMARCERON : Le «coup de lumière» acridinique. Son traitement préventif par la résorcine, Bull. de Soc. franç. de dermat. et syph., 1925, xxxii, 358-362. Google Scholar JESIONEKTAPPEINER AH: Zur Behandlung der Hautcarcinome mit fluorescierenden Stoffen, Deutsch. Arch. f. klin. Med., 1905, lxxxii, 223-227. Google Scholar LASSEN HC: Über die Lichtsensibilization im Ultraviolett, Strahlentherapie, 1928, xxvii, 757-768. Google Scholar LEVY AG: The pathological action of light, Jr. Path. and Bact., 1929, xxxii, 387-399. CrossrefGoogle Scholar MACHTANDERSON DIWT: Clinical and experimental studies on phototherapy in pernicious anemia, Jr. Pharm. and Exp. Med., 1928, xxxiv, 365-389. Google Scholar MASONFARNHAM VRRM: Acute hematoporphyria (report of two cases), Arch. Int. Med., 1931, xlvii, 467-483. CrossrefGoogle Scholar MEYER-BETZ F: Untersuchungen über die biologische (photodynamische) Wirkung des Hämatoporphyrins und anderer Derivate des Blut- und Gallenfarbstoffs. Deutsch. Arch. f. klin. Med., 1913, cxii, 476-503. Google Scholar ROTHMAN PE: Hematoporphyrinuria, Am. Jr. Dis. Child., 1926, xxxii, 219-225. CrossrefGoogle Scholar SMITH HL: Buckwheat poisoning (with report of a case in man), Arch. Int. Med., 1909, iii, 350-359. CrossrefGoogle Scholar STRAUCH CB: Photosensitization, Am. Jr. Dis. Child., 1930, xl, 800-803. Google Scholar VIDEBECH H: Klinisches, und Experimentealles über die Lichtsensibilisation durch Trypaflavin. Mit besonderem Hinblick auf die lokale Lupusbehandlung, Strahlentherapie, 1931, xli, 417-434. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: HAROLD F. BLUM, Ph.D.Affiliations: Berkeley, CaliforniaFrom the Division of Physiology, University of California Medical School, Berkeley, California.Presented at the Sixteenth Annual Clinical Session of the American College of Physicians, Berkeley, California, April 7, 1932. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byABNORMAL SENSITIVITY TO LIGHT IN A CASE OF POSSIBLE LANDRY'S PARALYSIS*H. F. BLUM, I. C. SCHUMACHER, F.A.C.P.Buckwheat sensitivity 1 January 1933Volume 6, Issue 7 Page: 877-884 Keywords Bacteria Cells ePublished: 1 December 2008 Issue Published: 1 January 1933 PDF downloadLoading ...