tbuckley/cabot-search huggingface dataset:
Multidrug-Resistant Tuberculosis in a Hospital—Jersey City, New Jersey, 1990-1992
Journal: JAMA (1994)

Since 1986 (the first full year following implementation of the revised tuberculosis [TB] surveillance case definition), the reported rate of TB per 100,000 persons in New Jersey increased from 9.5 cases to 12.6 cases in 1992. Of the 984 cases reported to CDC from New Jersey in 1992, 108 (11.0%) were reported from Jersey City (1990 population: 230,300)--the city ranked second in number of TB cases reported and fourth in rate of TB (46.9 per 100,000) in the state. In addition, in 1992, the rate of multidrug-resistant TB (MDR-TB) (i.e., Mycobacterium tuberculosis isolates resistant to at least isoniazid [INH] and rifampin [RIF]) among TB patients in New Jersey was 5%; the rate in Jersey City was 13%. To characterize the epidemiologic features of persons with drug-resistant TB, the New Jersey Department of Health and the Infectious Diseases Division of the Jersey City Medical Center conducted a study among patients treated at that hospital during 1990-1992. This report presents the findings of the study and compares the hospital's rates of drug-resistant TB with previously reported rates, rates for other cities in New Jersey, and rates for the state.
This Week in &lt;EMPH TYPE="ITAL"&gt;JAMA&lt;/EMPH&gt;
Journal: JAMA (2004)

Some promising anticancer drugs hit multiple targets on tumor cells, a property scientists say may help forestall the development of resistance to the treatment. SEE PAGE 419 Diagnosing Intra-amniotic InfectionNovel amniotic fluid proteins identified in a primate model of intra-amniotic infection (IAI) were found in the amniotic fluid and serum of women with subclinical IAI and could foster development of rapid and noninvasive diagnostic assays for occult IAI.
A call to arms
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Studying Oxygen's Life-and-Death Roles If Taken From or Reintroduced Into Tissue
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Queen Self-Regulating X-Ray Tube.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Progesterone metabolites and bile acids in serum of patients with intrahepatic cholestasis of pregnancy: Effect of ursodeoxycholic acid therapy
Authors: L Meng
Journal: Hepatology (1997)

The concentrations in serum of sulfated metabolites of progesterone are known to be elevated in patients with intrahepatic cholestasis of pregnancy (ICP). The profiles of these metabolites and conjugated bile acids were analyzed in serum from 11 patients with ICP before and during administration of ursodeoxycholic acid (UDCA) (8 patients) or placebo (3 patients). The clinical condition of 7 of the patients given UDCA improved markedly, and 1 patient given placebo had a spontaneous remission of the disease. The total concentration of conjugated bile acids in the 11 patients was 25 ± 6 micromol/L (mean ± SEM) and decreased to 6.3 ± 3.5 micromol/L in the 7 patients responding to treatment with UDCA. The level of 7α-hydroxy-4-cholesten-3-one was significantly lower (7.2 ± 2.2 ng/mL) in patients with ICP than in healthy pregnancy (18 ± 4.6 ng/mL) (P < .05). The concentrations of 5α-pregnane-3α,20α-diol mono- and disulfates decreased by 52% ± 7.9% and 68% ± 5.5%, respectively, in the patients responding to treatment. Similar decreases were observed for the mono- and disulfates of 5α-pregnane-3α,20α,21-triol and 5β-pregnane-3α,20α-diol. The disulfate of 5α-pregnane- 3β,20α-diol showed a smaller decrease, while glucuronidated steroids were not affected. The 3α-/3β-hydroxysteroid ratio and di-/monosulfate ratio decreased significantly during UDCA. The magnitudes of the changes of bile acid and steroid concentrations during UDCA were not correlated to each other. The results suggest that UDCA stimulates the biliary excretion of steroids with a 3α-sulfoxy group and disulfates. This effect seems to be independent of the effect on bile acid excretion, indicating the use of different transport proteins. The possibility of an effect of UDCA on the formation of the steroid sulfates cannot be excluded.
Michigan Medicine
Journal: JAMA (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Inhibition of Constitutive and Inducible Nitric Oxide Synthase: Potential Selective Inhibition
Authors: J. M. Fukuto
Journal: The Annual Review of Pharmacology and Toxicology (1995)

Due to the massive data sets available for drug candidates, modern drug discovery has advanced to the big data era. Central to this shift is the development of artificial intelligence approaches to implementing innovative modeling based on the dynamic, ...Read More
Jimson Weed
Authors: Gary M. Oderda
Journal: JAMA (1975)

<h3>To the Editor.—</h3> Although reports in the current literature are few, the intentional use of Jimson weed (<i>Datura stramonium</i>) to produce a "high," as described by Dr. Mahler (231:138, 1975) has become quite popular. Jimson weed will produce a "high" if its parts are smoked or eaten. The "high" is accompanied by many unpleasant, and dangerous, side-effects. These side-effects, as described by Dr. Mahler, are anticholinergic in nature. During 1974, several cases of intentional Jimson weed ingestions treated in Maryland emergency rooms were reported to our Center. The worst month was November, with six individual cases, all patients being between 15 and 17 years of age. Two of these patients required hospitalization. Our Center, following the recommendation of Dr. Barry Rumack,<sup>1</sup>recommends the use of a physostigmine salicylate-sodium bisulfate-benzyl alcohol mixture (Antilirium) for anticholinergic intoxication, including that with Jimson weed. Adolescents and adults are given a 2-mg intravenous test
Rabies vaccination
Authors: P. Diamond
Journal: JAMA (1988)

<h3>In Reply.</h3> —We disagree with a number of Dr Diamond's statements about rabies and rabies postexposure prophylaxis. Postexposure prophylaxis failures with rabies immune globulin<i>and</i>cell-culture vaccines (eg, human diploid cell rabies vaccine [HDCV]) are rare occurrences. As stated in the editorial note of the LEADS FROM THE MMWR article that appeared in<i>JAMA</i>, only two laboratory-confirmed cases of rabies occurring despite administration of rabies immune globulin and HDCV within 24 hours of exposure have been reported during the ten-year period that cell-culture vaccines have been used worldwide. We have been in communication with Dr Wasi regarding eight other possible cases of rabies despite postexposure prophylaxis with rabies immune globulin and cell-culture vaccine. However, none of these patients had received rabies immune globulin and cell-culture vaccine within 24 hours of exposure. In addition, it is unclear how rabies immune globulin and vaccine were administered, what type of local wound care
The key role of levator ani thickness for early urinary continence recovery in patients undergoing robot-assisted radical prostatectomy: A multi-institutional study
Authors: M. Tutolo, G. Rosiello, F. Van Der Aa, G. Stabile, D. Oreggia, F. Barletta, S. Scuderi, D. Cannoletta, L. De Wever, D. De Ridder, G. Tasso, W. Everaerts, A. Esposito, F. De Cobelli, A. Salonia, F. Montorsi, A. Briganti
Journal: European Urology (2021)
Burst-like control of lipolysis by the sympathetic nervous system in vivo
Authors: K. Hucking
Journal: Journal of Clinical Investigation (2003)

Rapid oscillations of visceral lipolysis have been reported. To examine the putative role of the CNS in oscillatory lipolysis, we tested the effects of β3-blockade on pulsatile release of FFAs. Arterial blood samples were drawn at 1-minute intervals for 120 minutes from fasted, conscious dogs (n = 7) during the infusion of saline or bupranolol (1.5 μg/kg/min), a high-affinity β3-blocker. FFA and glycerol time series were analyzed and deconvolution analysis was applied to estimate the rate of FFA release. During saline infusion FFAs and glycerol oscillated in phase at about eight pulses/hour. Deconvolution analysis showed bursts of lipolysis (nine pulses/hour) with time-dependent variation in burst frequency. Bupranolol completely removed rapid FFA and glycerol oscillations. Despite removal of lipolytic bursts, plasma FFAs (0.31 mM) and glycerol (0.06 mM) were not totally suppressed and deconvolution analysis revealed persistent non-oscillatory lipolysis (0.064 mM/min). These results show that lipolysis in the fasting state consists of an oscillatory component, which appears to be entirely dependent upon sympathetic innervation of the adipose tissue, and a non-oscillatory, constitutive component, which persists despite β3-blockade. The extinction of lipid fuel bursts by β3-blockade implies a role for the CNS in the maintenance of cyclic provision of lipid fuels.
An Essentially Woman's Hospital.
Journal: JAMA (1889)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Corrections
Journal: American Journal of Psychiatry (2009)

For the Dec. 2008 CME quiz for "Trauma, Resilence and Recovery in a High-Risk African-American Population", options B and C for question 1 were identical, with correct credit only given for selecting option B. This is because option B should have read "Lower exposure to assaultive trauma was present in the resilient group compared to the recovered and currently ill groups," which, as the question requests, is the most accurate reflection of the influence of previous trauma exposure on resilience and recovery from psychiatric disorders.The online quiz will be corrected.
Teaching adolescents to say 'no' to tobacco
Authors: K. Simmons
Journal: JAMA (1985)

Adolescents may be more likely to practice preventive health measures when they're informed of the immediate, rather than the long-term, effects of "maladaptive" habits that can lead to heart disease, according to researchers at the Stanford University Center for Research in Disease Prevention, Palo Alto, Calif. Focusing on the immediate negative effects of smoking, such as reduced attractiveness and poor stamina, may dissuade adolescents from adopting the habit, says Michael Telch, PhD, who, along with Joel Killen, PhD, is codirector of the Stanford Adolescent Health Project. The first aim of the health project, says Telch, is to make students more receptive to changing their life-styles. In classes conducted three times a week by Stanford graduates, many of whom are now in medical school or are preparing in some other way for a medical career, adolescents are taught how to take control of their lives in general (in relationships with parents,
The effect of the 1992 California motorcycle helmet use law on motorcycle crash fatalities and injuries
Authors: J. F. Kraus
Journal: JAMA (1994)

<h3>Objective.</h3> —To determine the effects of the California motorcycle helmet use law on statewide fatalities and a large sample of nonfatal injuries before and after law implementation. <h3>Design.</h3> —Police reports and death certificates were collected for motorcycle crash fatalities in California for 1991 (prelaw) and 1992 (postlaw). Official counts of registered motorcycles provided a statewide basis for exposure to a motorcycle crash. Autopsy results were collected for fatalities in 11 counties. Hospital records were reviewed for nonfatal injuries in 28 hospitals in 10 of the 11 counties. Police reports were linked to injury data for the riders. <h3>Subjects and Patients.</h3> —A total of 850 fatalities and injury data for 547 fatally injured riders and 3252 nonfatally injured patients. <h3>Main Outcome Measures.</h3> —Changes in number and rates among statewide fatalities were estimated. The number and pattern of head injuries in fatally and nonfatally injured motorcycle riders were evaluated. <h3>Results.</h3> —After implementation of the helmet use law, statewide motorcycle crash fatalities decreased by 37.5%, from 523 fatalities in 1991 to 327 in 1992, more than 37%, and an estimated 92 to 122 fatalities were prevented. Motorcycle fatality rates were reduced by 26.5%, from 70.1 per 100 000 registered motorcycles in 1991 to 51.5 per 100000 in 1992. Head injuries decreased significantly among both fatally and nonfatally injured motorcyclists. <h3>Conclusion.</h3> —Enactment of an unrestricted helmet law significantly reduces the incidence of motorcycle crash fatalities and the number and severity of head injuries. (<i>JAMA</i>. 1994;272:1506-1511)
The Olympic Games
Journal: JAMA (1972)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Homosexual youth. A challenge to contemporary society
Authors: G. Remafedi
Journal: JAMA (1987)

DURING the 1980s, health professionals and laypersons alike have confronted the subject of homosexuality on a daily basis in journals and books, on radio and television, primarily in the context of the acquired immunodeficiency syndrome (AIDS) pandemic. Despite an unprecedented public awareness of adult homosexuality and its relevance to a variety of individual and public health issues, disproportionately little attention has been focused on the antecedents of homosexuality in childhood and adolescence. Although the prevalence of adolescent homosexual behavior is well recognized, some authorities<sup>1</sup>"clearly reject"<sup>2</sup>the notion that a homosexual orientation can be established prior to adulthood. Unlike other cultures, including Native American communities,<sup>3</sup>modern American society views heterosexuality as the only possibility for its young. The homosexual adult, as if by parthogenesis, springs from the heterosexual child at the age of 18 years. Not only does this perspective preclude understanding the origins and development of
Commparison of Differential Agglutination Titre (D.A.T.) in Juvenile and Adult Rheumatoid Arthritis
Journal: Annals of the Rheumatic Diseases (1962)

RHEUMATIC DISEASES and claims that the results were excellent i good in 17 per cent., and poor in 10 per ce [This paper fails to convince.In tent example, which falls within the definitic point phenomenon, pain can also be elicit the forearm extensors into tension; m( proportion of such cases (especially if t bilateral) in spite of local signs and sympton cause is found to lie in the cervical spine.]
Travel Medicine
Authors: Peter A. Leggat
Journal: JAMA (2010)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Long stents: Angiographic detection of the area with the highest lumen loss after implantation of long (&gt;20 mm) stents Thomas F. M. Konorza, Michael Haude, Martin Diedrich, Carsten Kretz, Christoph Kaiser, Heinrich Wieneke, Nikolaos Dagres, Dietrich Baumgart, Christoph Naber, Raimund Erbel. University of Essen, Essen, Germany
Journal: Journal of the American College of Cardiology (2001)
Canadian Journal of Surgery, Toronto
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal