tbuckley/cabot-search huggingface dataset:
SportsMedUpdate
Authors: Martin P Schwellnus
Journal: British Journal of Sports Medicine (2011)

1. Rompe JD, 2. Cacchio A, 3. Furia JP, 4. et al . Low-energy extracorporeal shock wave therapy as a treatment for medial tibial stress syndrome. Am J Sports Med 2010;38:125–32. [OpenUrl][1][Abstract/FREE Full Text][2] ### Background Extracorporeal shock wave therapy (SWT) is used in the treatment of insertional tendinopathy—medial tibial stress syndrome (MTSS) is typically painful at the insertion of the tibialis posterior or soleus muscles. ### Research question/s Does extracorporeal SWT reduce pain and improve function in chronic MTSS? ### Methodology Subjects 94 patients with chronic recalcitrant MTSS (<6 months) Experimental procedure In a non-randomised fashion, subjects were treated with either a 12-week standardised home training programme (stretches, resistance exercises) only (CON=47, female=26) or home training and repetitive low-energy radial shock wave therapy (SWT=47, female=28, 3 weekly sessions, 2000 shocks per session; 2.5 bars equal to 0.1 mJ/mm2; total energy flux density, 200 mJ/mm2; no local anaesthesia). Outcomes were measured at 0, 1, 4 and 15 months. Measures of outcome Recovery 6-point Likert scale—success=rating of 1 (completely recovered) or 2 (much improved); pain in past week (numeric rating 0–10). ### Main finding/s Return to sport at 15 months: Ability to return to their preferred sport at their preinjury level at 15 months: SWT group=40/47 subjects, CON group=22/47 subjects. ### Conclusion/s In a non-randomised controlled study, radial extracorporeal shock wave therapy was effective in reducing pain and improving function in patients with chronic medial tibial stress syndrome. Evidence-based rating : 7.5/10 Clinical interest … [1]: {openurl}?query=rft.jtitle%253DAm%2BJ%2BSports%2BMed%26rft_id%253Dinfo%253Adoi%252F10.1177%252F0363546509343804%26rft_id%253Dinfo%253Apmid%252F19776340%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=amjsports&resid=38/1/125&atom=%2Fbjsports%2F45%2F2%2F152.atom
<i>QuickStats:</i> Percentage* of Emergency Department (ED) Visits Made by Adults with Influenza and Pneumonia† That Resulted in Hospital Admission, by Age Group — United States, 2017–2018§
Authors: Loredana Santo, Jill Ashman, Susan Schappert
Journal: MMWR Morbidity and Mortality Weekly Report (2020)

With 95% confidence intervals shown with error bars.
Preventing injuries in children: cluster randomised controlled trial in primary care
Journal: BMJ (1999)

Objective To assess the effectiveness of safety advice at child health surveillance consultations, provision of low cost safety equipment to families receiving means tested state benefits, home safety checks, and first aid training on frequency and severity of unintentional injuries in children at home.Design Cluster randomised controlled trial.Setting 36 general practices in Nottingham.Subjects All children aged 3-12 months registered with participating practices.Interventions A package of safety advice at child health surveillance consultations at 6-9, 12-15, and 18-24 months; provision of low cost safety equipment to families on means tested state benefits; and home safety checks and first aid training by health visitors.Outcome measures Primary outcomes measures were frequency and severity of medically attended injuries.Secondary outcome measures were self reported safety practices, possession and use of safety equipment, knowledge and confidence in dealing with first aid, and perceptions of risk of injury and risk of hazards assessed by postal questionnaire at baseline and follow up at 25 months.Results At baseline, both groups had similar risk factors for injury, sociodemographic characteristics, safety practices, possession and use of safety equipment, knowledge and confidence in dealing with first aid, and perceptions of risk.No significant difference was found in frequency of at least one medically attended injury (odds ratio 0.97, 95% confidence interval 0.72 to 1.30), at least one attendance at an accident and emergency department for injury (1.02, 0.76 to 1.37), at least one primary care attendance for injury (0.75, 0.48 to 1.17), or at least one hospital admission for injury (0.69, 0.42 to 1.12).No significant difference in the secondary outcome measures was found between the intervention and control groups.Conclusions The intervention package was not effective in reducing the frequency of minor unintentional injuries in children at home, and larger trials are required to assess the effect on more severe injuries.Requested interventions (home safety checks, safety equipment, and first aid training only): None (n=243; 22.1%) 1 (n=297; 27.0%) 2 (n=297; 27.0%) 3 (n=159; 14.5%) 4 (n=82; 7.5%) 5 (n=21; 1.9%) 6 (n=1; 0.1%) Received interventions including advice at 3 child health surveillance checks which could not be requested: Control group (n=1019)
House Of Delegates Meets
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 812: γ-tocotrienol induces mitophagy in breast cancer cells through activation of LKB1-AMPK pathway
Authors: Venkatesh Dronamraju, Paul W. Sylvester
Journal: Cancer Research (2019)

Abstract The dysregulation of glucose metabolism in cancer cells manifests as a characteristic phenomenon, referred to as the Warburg effect. Warburg effect is an over-reliance on aerobic glycolysis by cancer cells to meet the energy demand of proliferation. Previous studies have shown that γ-tocotrienol, a natural vitamin E derivative, inhibits aerobic glycolysis in human breast cancer cells through its modulation of key regulatory enzymes protein kinase B (Akt) and 5’-AMP activated kinase (AMPK). In the present study, we investigated the effects of γ-tocotrienol-induced activation of AMPK on mitochondrial dynamics in human breast cancer cells. Western blotting and immunocytochemistry analysis revealed that in human breast cancer cells MDA-MB-231 and T-47D, γ-tocotrienol removed the negative regulation of Akt on liver kinase B1 (LKB1), an upstream promoter of AMPK by increasing active complex formation and cytosolic localization of LKB1. In addition, γ-tocotrienol-induced activation of AMPK improved mitochondrial membrane potential through inhibition of uncoupling protein 1 (UCP1) as revealed by western blot analysis and mitochondrial membrane potential assay. High performance liquid chromatography (HPLC) analysis of NAD+/NADH ratio showed that γ-tocotrienol-induced AMPK activation improved the NAD+ ratio in human breast cancer cells, which indicates improving mitochondrial oxidative phosphorylation. In addition, γ-tocotrienol induced AMPK activation in human breast cancer cells causes increased mitochondrial fission, an indicator of mitophagy, as revealed by Western blot analysis of mitochondrial fission factor (MFF). In summary, these results show that γ-tocotrienol-induced AMPK activation modulates metabolic reprogramming in part by influencing the mitochondrial dynamics in human breast cancer cells. This work was supported in part by funds provided by the Louisiana Cancer Foundation. Citation Format: Venkatesh Dronamraju, Paul W. Sylvester. γ-tocotrienol induces mitophagy in breast cancer cells through activation of LKB1-AMPK pathway [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 812.
THIAMINE IN THE AMERICAN DIET
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Medical Gynecology.
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The New Medical Law of Virginia.
Journal: JAMA (1884)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction
Journal: BMJ (1992)

his elderly patients.A particular interest was obtaining adequate compensation for his patients with silicosis.In 1958 he was elected chairman of the local branch of the BMA.A devout Christian, Tom served on his church's management committee for many years.A keen sportsman, he had played football for Glasgow University and Hamilton Academicals.Until he developed arthritis he was an enthusiastic golfer.Despite cataract surgery and two hip replacements he kept his large garden in impeccable order.His wife, Marcilla, died 10 years ago; they did not have any children.-
Study Under Way on Effects of Chernobyl Fallout on Childhood Cancer Rates
Journal: JNCI Journal of the National Cancer Institute (1994)

Journal Article Study Under Way on Effects of Chernobyl Fallout on Childhood Cancer Rates Get access JNCI: Journal of the National Cancer Institute, Volume 86, Issue 6, 16 March 1994, Page 421, https://doi.org/10.1093/jnci/86.6.421 Published: 16 March 1994
Pseudotumor Cerebri in Children Secondary to Administration of Adrenal Steroids
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Efficacy of whooping-cough vaccines used in the United Kingdom before 1968: A preliminary report by the public health laboratory service whooping-cough committee and working party
Authors: J -Abbott, P Manchester, A Antonis, P Colindale, H Cayton, P Bristol, R Cruickshank, J Duguid, W Dunnet, T Elias-Jones, J Emslie, P Middlesbrough, E Gillespie, P Sheffield, R Gillies, J Gostling, P Portsmouth, J Hale, P Newcastle, R Henderson, P Worcester, P Higgins, H Johnston, P Oxford, L Little, P Wakefield, N Mair, P Leicester, E Mitchell, P Nottingham, B Moore, D Payne, F Perkins, M Hampstwad, Sheila Polakoff, T Colindale, Pauline Colindale, P Poole, N Chester, H Smith, P Bradford, A Standfast, I Stewart, P Coventry, I Taylor, Mair Thomnas, Scott Thompson, P Cardiff, G Turner, P Liver- Pool, J Warin, M City Of Oxford, J Whitehead, A Wison, P Wormald, P Salisbury, A Wright, P Gloucester, E Armstrong, D Green, W Ryan, E Bebbingtori, W Turner, J Douglas, R Wofinden, W Phillips, Cheltenham Lawson, T Clayton, W Pollitt, Ellesmere Port, E Irvine, P Regester, S Knight, J Cairns, W Cormack, S Hewitt, B Moss, A Semple, Kennedy Campbell, C Metcalfe, R Pearson, W Dodd, P Roads, R Donaldson, C Shaw, W Sharpe, R Taylor, G Firth, C Thompson, E Wright, Waltham Forest, E Moore, C Lycett, G O'donnell
Journal: BMJ (1969)

In a large survey of the efficacy of pertussis vaccines made in 33 areas in the United Kingdom during the period 1 November 1966 to 31 October 1967 a total of 3,564 households were investigated. Nine hundred and seventy-seven strains of Bordetella pertussis and 6 strains of Bord. parapertussis were isolated from persons in 792 households. After contact in the home 56% of fully vaccinated children under 5 years of age developed a paroxysmal cough, and in more than two-thirds of these patients the diagnosis was confirmed bacteriologically. This suggests that pertussis vaccination was not very effective. A comparison with the attack rate in unvaccinated children also indicates a poor protection from vaccination. None of the following factors appeared to be responsible for the poor protection afforded by vaccination: vaccination in early infancy, a long interval since vaccination, and the absence of booster doses. Almost all the children in the survey had been given vaccines from a single manufacturer, and therefore a comparison of the efficacy of vaccines prepared by different manufacturers was inconclusive. All the vaccinated children in the survey had been vaccinated before or during 1967. The efficacy of current preparations will require to be assessed by continuing surveillance.
Implantation: timing is everything.
Journal: Environmental Health Perspectives (1999)

Understanding the many facets of human reproduction has long been considered a guessing game. According to Allen Wilcox, chief of the Epidemiology Branch at the NIEHS, until now, knowing exactly when implantation of an egg into the uterine wall occurs has been impossible because the event has never been observed in humans. However, Wilcox and his team have recently taken some of the guessing out of the process by shedding light on how the timing of implantation may affect a pregnancy's outcome. The results of their research were published in the 10 June 1999 issue of the New England Journal of Medicine.
Why Do Parents Decline Vitamin K for Their Newborns?
Journal: JAMA (2014)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mystic Statistic
Authors: Stanley S. Schor
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
On the Physical Death of Jesus Christ
Authors: Joel S. Glasser
Journal: JAMA (1986)

<h3>To the Editor.—</h3> I was stunned to find in the pages of<i>JAMA</i>the essay by Edwards et al,<sup>1</sup>presented as "not a theological treatise but rather a medically and historically accurate [sic] account of the physical death of the one called Jesus Christ." Although the Gospels that tell the story of the passion of Jesus were compiled decades after the events described (Mark, circa 70 AD, through John, circa 110 AD), and without benefit of eyewitness or other extant records of that community, the authors nevertheless state, "The most extensive and detailed description of the life and death of Jesus are to be found in the New Testament Gospels." The reference cited is<i>The Holy Bible</i>. Of course, for traditional Christians the contents of the Gospels are incontrovertible articles of faith; in the context of fundamentalist religious belief the historicity, or even plausibility, of the details ("facts") becomes
Erratum: Lung Ultrasound for Critically Ill Patients
Authors: Lucile Ses, Catherine Cavalin
Journal: American Journal of Respiratory and Critical Care Medicine (2020)

chronic diseases over a long period of time through a holistic multidisciplinary evaluation, including the wider SES and psychological influences on the individual, over the lifespan.In the case of IPF, this approach may be crucial for understanding its onset, evolution, and complex gene-environment interactions.The development of modern tools such as mobile health devices and remote sensors enables an exposomic approach through the generation of big data, which can be implemented in IPF registries.To sum up, to accurately investigate IPF, it is important to take into account the impact of air pollution, occupational exposure, and SES in patient registries, and to apply these factors through the lens of the exposome.This approach is closely connected with multidisciplinary research involving population epidemiology, environmental justice, and science and technology studies examining patients' living conditions.
AORTOGRAPHY
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal