Inactivated Hepatitis B Virus Vaccine
Journal: Annals of Internal Medicine (1982)

Diagnosis and Treatment1 September 1982Inactivated Hepatitis B Virus VaccineRecommendation of the Immunization Practices Advisory CommitteeAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-97-3-379 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail AbstractAbstractWorldwide, recommendations for using hepatitis B virus (HBV) vaccine will vary in accordance with local patterns of HBV transmission. In the United States, an area of low HBV prevalence, certain groups are at substantially greater risk than the general population of acquiring infection. It is for these higher-risk groups that the vaccine is currently recommended. To date, 12 000 individuals have been given this vaccine, and no untoward effects have been observed over periods of time extending up to 3 years. The recommendations that follow are intended as initial guides for immunization practice, and will be modified as additional data and experience are accumulated. Because the cost of this vaccine is high, a discussion of the cost effectiveness of prevaccination susceptibility testing is included.References1. KRUGMANHOLLEYDAVIDSON SHM. Immunogenic effect of inactivated hepatitis B vaccine: comparison of 20 g and 40 µg doses. J Med Virol. 1981;8:119-21. CrossrefMedlineGoogle Scholar2. SZMUNESSSTEVENSHARLEY WCE. The immune response of healthy adults to a reduced dose of hepatitis B vaccine. J Med Virol. 1981;8:123-9. CrossrefMedlineGoogle Scholar3. SZMUNESSSTEVENSHARLEY WCE. Hepatitis B vaccine: demonstration of efficacy in a controlled clinical trial in a high-risk population in the United States. N Engl J Med. 1980;303:833-41. CrossrefMedlineGoogle Scholar4. FRANCISHADLERTHOMPSON DSS. The prevention of hepatitis B with vaccine: report of the Centers for Disease Control multi-center efficacy trial amoung homosexual men. Ann Intern Med. 1982;97:362-6. LinkGoogle Scholar5. . Immune globulins for protection against viral hepatitis. Morbid Mortal Weekly Rep. 1981;30:423-35. MedlineGoogle Scholar6. DIENSTAGSTEVENSBHAN JCA. Hepatitis B vaccine administered to chronic carriers of hepatitis B surface antigen. Ann Intern Med. 1982;96:575-9. LinkGoogle Scholar7. SZMUNESSSTEVENSOLESZKO WCW. Passive-active immunisation against hepatitis B: immunogenicity studies in adult Americans. Lancet. 1981;1:575-7. CrossrefMedlineGoogle Scholar8. PATTISONMAYNARDBERQUISTWEBSTER CJKH. Epidemiology of hepatitis B in hospital personnel. Am J Epidemiol. 1975;101:59-64. CrossrefMedlineGoogle Scholar9. DIENSTAGRYAN JD. Occupational exposure to hepatitis B virus in hospital personnel: infection or immunization. Am J Epidemiol. 1982;115:26-39. CrossrefMedlineGoogle Scholar10. MAYNARD J. Viral hepatitis as an occupational hazard in the health care profession. In: VYAS GN, COHEN SN, SCHMID R, eds. Viral hepatitis. Philadelphia: Franklin Institute Press, 1978:321-31. Google Scholar11. BEASLEYHWANGLIN RLC. Hepatitis B immunoglobulin (HBIG) efficacy in the interruption of perinatal transmission of hepatitis B virus carrier state. Lancet. 1981;2:388-93. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: ▸From the Immunization Practices Advisory Committee, Centers for Disease Control; Atlanta, Georgia. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byEndocrine EmergenciesSEXUALLY TRANSMITTED VIRUSES OTHER THAN HIV AND PAPILLOMAVIRUSEfficacy of Hepatitis B Vaccine in Continuous Ambulatory Peritoneal Dialysis Patients Is Influenced by Blood TransfusionPrevalence of isolated antibody to hepatitis B core antigen in an area endemic for hepatitis B virus infection: Implications in hepatitis B vaccination programsHepatitis B exposure and the emergency physician: Risk assessment and hepatitis vaccine updateHepatitis B Program for Health Care Personnel: Education, Serologic Surveillance, ImmunizationRecent developments in viral hepatitisSelected Serology: Pregnancy Testing, Hepatitis A and B, Infectious MononucleosisHepatitis B vaccine: Low postvaccination immunity in hospital personnel given gluteal injectionsOccupational Hazards to Hospital PersonnelWILLIAM B. PATTERSON, M.D., DONALD E. CRAVEN, M.D., DAVID A. SCHWARTZ, M.D., EDWARD A. NARDELL, M.D., JEAN KASMER, M.D., JOHN NOBLE, M.D.Hepatitis B vaccinationClinical and immunologic features of chronic dialysis patients who fail to respond to hepatitis B vaccineHepatitis and the dentistInactivated hepatitis B virus vaccineViral Hepatitis 1 September 1982Volume 97, Issue 3Page: 379-383KeywordsHepatitis B virusVaccines ePublished: 1 December 2008 Issue Published: 1 September 1982 PDF downloadLoading ...