tbuckley/cabot-search huggingface dataset:
Low-dose intradermal hepatitis B vaccine
Authors: J. L. Dienstag
Journal: JAMA (1986)

<h3>To the Editor.—</h3> In a recent report from the Walter Reed Army Institute of Research, Redfield and colleagues<sup>1</sup>presented the results of a study in which 2 μg of hepatitis B vaccine administered intradermally (ID) to 25 health workers was compared with the standard 20-μg dose administered intramuscularly (IM) to another 25 health workers. Based on similar seroconversion rates and antibody levels achieved, these investigators concluded that the low-dose ID regimen was comparable in immunogenicity with the IM regimen. Obviously, if ID administration requires one-tenth the dose of the IM route, the potential savings in vaccine costs would make this vaccine more affordable and, therefore, more available than it is now. For the military, already under budgetary pressure to limit spending, the dollar savings for a mass vaccination program of military personnel rotating for brief tours of duty through high-risk areas of the world would be substantial. On the
Bacterial Meningitis
Authors: Jerry J. Eller
Journal: JAMA (1986)

This is a 272-page authoritative text written by 27 separate authors including many of the most active investigators in the field. In 16 chapters, the authors comprehensively present relevant new information concerning all aspects of bacterial meningitis. Each chapter concludes with a bibliography that contains a review of the most recently published literature and often key historical references. There is an excellent blending of scientific information with practical clinical applications. In early chapters, there is a definite emphasis on pathogenesis, including the microbiology of infectious agents and immunology of host responses, and the pathophysiology of acute bacterial meningitis. The authors are lucid to the point that the reader can deduce those logical points where the clinician might intervene to stop or at least modify the progression of the disease process. The clarity of presentation of clinical material enables the reader readily to correlate the pathophysiology with clinical findings and laboratory
Prevention of suicide.
Journal: BMJ (1971)

first suggested."1Furthermore, a thoracic duct fistula is difficult to keep draining for more than a few days, and once it becomes occluded bleeding is likely to recur.In summary the control of oesophageal haemorrhage remains an unsolved problem, while the prognosis is deter- mined largely by the patient's liver function.The desirability, timing, and nature of any of the possible surgical procedures are still not established.
GAMBLING AND THE GAMBLER
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Report of the Librarian
Authors: Henry R. Viets
Journal: New England Journal of Medicine (1956)

THE Librarian herewith presents his annual reA port, the eighteenth accounting of the state of the Library since he took office in 1938. The report covers the calendar year 1955, another year of increased attendance following a pattern of an upward trend of usefulness, continuous since the end of World War II. Both the figures for circulation and those for attendance were the largest ever recorded, over 74,000 items being used by more than 17,000 readers. The Library grew in size at its regular rate, adding over 4000 books to reach a total of 228,770 catalogued volumes. With the catalogued . . .
ABSTRACTS
Authors: Mario Baldini, Klaus Betke, Arthur Bloom, Thomas Bothwell, S Africa, Jacques Caen, Jyoti Chatterjea, Pietro Denicola, Ludvik Donner, Patricia Fames, Ira Green, Frederick Cunz, N Yamaguchi, W Rosenthal, G Glass, S Harper, E Drenick, Al Swendseid, J Ghitis, K Tripathy, S Seurkovich, N K' Sijak, L Machonoca
Journal: Blood (1970)
皮肤科期刊发表的系统综述中的报告质量
Authors: D.O. Croitoru, Y. Huang, A. Kurdina, A.W. Chan, A.M. Drucker
Journal: British Journal of Dermatology (2020)

系统综述 (SR) 被认为是医疗保健部门收集证据的黄金标准。它们通过总结我们拥有的有关医学主题的可用数据,同时强调文献中现有研究的质量,服务于临床医生和医疗保健领域的其他利益相关者,如患者和政策制定者。 在其他医学专业的文献中,对报告指南的使用,如系统综述和荟萃分析 (PRISMA) 的首选报告项目,已被证明增加了透明度和重现性(重复实验时获得一致结果的程度)。 然而,到目前为止,还没有研究关注皮肤病 SR 遵守 PRISMA 指南中的项目的情况,这也是这项研究的作者(位于加拿大)旨在解决的问题。重要的是,系统综述的方法是透明的,并以适当的方式进行报告,这样读者可以清楚地了解做了什么,为什么要这样做。 为此,我们审查了 2013 至 2017 年间发表在影响因子最高的五种皮肤病杂志上的所有 SR。我们评价了对选定的 PRISMA 项目的报告情况,以及报告的依从性是否与发表年份、研究方案登记和资金来源等因素有关。 我们发现,在 2013 年至 2017 年发表在五种皮肤科杂志上的 SR 中,在所有综述(136 篇)中,每篇都至少涉及一项未得到充分报告的 PRISMA 项目,而 93%(136 篇中有 127 篇)的综述至少涉及一项完全没有报告的项目。随着时间的推移,报告有所改进,声明使用了预先登记的研究方案的 SR 都能更好地报告我们要评估的 PRISMA 项目。 有几个项目在皮肤病系统综述中仍然普遍报告不足,我们识别出了这些项目,希望这能改善以后的报告。 根据这项研究的结果,我们认为作者、审稿人、期刊编辑和编辑委员会应该努力鼓励预先登记 SR 研究方案以及更好地进行 SR 报告。 本摘要涉及研究:皮肤科期刊发表的系统综述中的报告质量
Inguinal hernias
Authors: John T Jenkins, Patrick J O’Dwyer
Journal: BMJ (2008)

Abdominal wall hernias are common, with a prevalence of 1.7% for all ages and 4% for those aged over 45 years.Inguinal hernias account for 75% of abdominal wall hernias, with a lifetime risk of 27% in men and 3% in women. 1 Repair of inguinal hernia is one of the most common operations in general surgery, with rates ranging from 10 per 100 000 of the population in the United Kingdom to 28 per 100 000 in the United States. 2 In 2001-2 about 70 000 inguinal hernia repairs (62 969 primary, 4939 recurrent) were done in England, requiring more than 100 000 hospital bed days.Ninety five per cent of patients presenting to primary care are male, and in men the incidence rises from 11 per 10 000 person years aged 16-24 years to 200 per 10 000 person years aged 75 years or above.
ESMO Guidelines Committee
Authors: Nicholas Pavlidis, Rolf Stahel, Fatima Cardoso, Elzbieta Senkus-Konefka, Dirk Arnold, Alan Horwich, Nicoletta Colombo, Lisa Licitra, Jean-Yves Blay, Ulrich Keilholz, Florian Strasser, Azza Hassan, Jørn Herrstedt, Keith Mcgregor, Claire Bramley, Jennifer Lamarre, Matthew Wallace, Aude Galli, Svetlana Jezdic
Journal: Annals of Oncology (2015)
Unidentified Corpse
Authors: C. J. Stahl
Journal: JAMA (1979)

<h3>To the Editor.—</h3> On Sept 26, 1976, a decomposed, headless, partially skeletonized body was found in a wooded area near the middle branch of the Chopawansic Creek at the Marine Corps Base, Quantico, Va. Pathological, anthropological, and roentgenographic examinations of the body indicated the remains were those of a white woman with an estimated living stature of 153 to 160 cm and an old, healed, nondisplaced fracture of the left ulna. Although the preliminary pathological and anthropological examinations resulted in the estimated range of age between 25 and 50 years, microscopic examination of cross sections of the tibia and the femur provided a more precise estimate of the age as 52±5 years. Parturition pits of the pelvis suggested the woman had had one or two childbirths. Roentgenographic evidence of growth cessation lines on several long bones also indicated she had had one or more severe childhood illnesses. The hair of
Creation of the physician-patient relationship. I
Authors: A. R. Holder
Journal: JAMA (1974)

CREATION of the physician-patient relationship is a matter of ordinary contract law in most circumstances. An "express" contract will be held to exist when a patient seeks out a physician and asks him to treat a specific ailment, and the physician agrees to do so. An "implied" contract, in law, is one that arises from the actions of the parties and not from a verbal agreement. It may arise between a physician and patient under many circumstances. Since a physician owes no duty of careful treatment to an individual who is not his patient, many court decisions involve attempts to determine whether or not an implied contract did in fact exist. <h3>Implied Contracts</h3> A typical example of a situation where a patient claimed that a given physician was, in fact, responsible for her care and the physician denied he had ever intended to undertake responsibility for her treatment was<i>Smart</i>
Alzheimer's disease, apolipoprotein E4, and gender
Authors: H. Payami
Journal: JAMA (1994)

<h3>To the Editor.</h3> —Researchers at Duke University have shown that apolipoprotein<i>E4</i>(apo E) gene dosage correlates with increased risk of Alzheimer's disease (AD).<sup>1</sup>Their study included members of 42 families with late-onset AD (age at onset, &gt;60 years) with known apo E genotype and used Kaplan-Meier survival analysis to estimate the age-of-onset curves for subjects with zero, one, and two<i>E4</i>alleles. The resulting curves revealed a significant dosage effect, where each additional<i>E4</i>allele shifted the onset to an earlier age. We have performed a similar study, which included members of 52 families with late-onset AD (age at onset, &gt;60 years) with known apo E genotype and used Kaplan-Meier survival analysis to estimate the age-of-onset curves for subjects with zero, one, and two<i>E4</i>alleles. Our study included 252 individuals with known age and apo E genotype; 38 were younger than 60 years,
Re: Christopher J.D. Wallis, Zachary Klaassen, Bimal Bhindi, et al. Comparison of Abiraterone Acetate and Docetaxel with Androgen Deprivation Therapy in High-risk and Metastatic Hormone-naïve Prostate Cancer: A Systematic Review and Network Meta-analysis. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2017.10.002
Authors: Claire Vale, David Fisher, Jayne Tierney, Ian White, Matthew Sydes, James Carpenter
Journal: European Urology (2017)
Correction: Changes in Drug Utilization during a Gap in Insurance Coverage: An Examination of the Medicare Part D Coverage Gap
Journal: PLoS Medicine (2014)

Since the manuscript's publication, the authors have been working on other, unrelated studies using the same database.The authors found results in these new, unrelated studies to be implausible and so undertook an intensive, several weeks-long investigation to determine whether the common database was in some way incorrectly assembled or was missing data.They found that a programmer in the group had failed to load 8 files of prescription and claims data into the dataset.This mistake occurred despite quality checks and resulted in the underreporting of prescription drug use in the database.The authors have now re-run all analyses for this study.In particular, because cohort entry in the Part D coverage gap study depends on prescription drug use, they now identify a larger number of patients and a larger number of drugs that can be studied.As a result, these analyses differ from those originally presented.The manuscript's main message remains the same.
CARBON DIOXIDE RETENTION IN OBSTRUCTIVE PULMONARY DISEASE
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
OUTLINE OF A SCHEME FOR WRITING THE NATURAL HISTORY OF SYPHILIS
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Quantification of microheterogeneity in glioblastoma multiforme with ex vivo high-resolution magic-angle spinning (HRMAS) proton magnetic resonance spectroscopy
Authors: Leo Ling Cheng, Douglas C. Anthony, Alison R. Comite, Peter M. Black, A. Aria Tzika, R. Gilberto Gonzalez
Journal: Neuro-Oncology (2000)

Microheterogeneity is a routinely observed neuropathologic characteristic in brain tumor pathology.Although microheterogeneity is readily documented by routine histologic techniques, these techniques only measure tumor status at the time of biopsy or surgery and do not indicate likely tumor progression.A biochemical screening technique calibrated against pathologic standards would greatly assist in predicting tumor progression from its biological activity.Here we demonstrate for the rst time that proton magnetic resonance spectroscopy ( 1 H MRS) with high-resolution magic-angle spinning (HRMAS), a technique introduced in 1997, can preserve tissue histopathologic features while producing well-resolved spectra of cellular metabolites in the identical intact tissue specimens.Observed biochemical alterations and tumor histopathologic characteristics can thus be correlated for the same surgical specimen, obviating the problems caused by tumor microheterogeneity.We analyzed multiple specimens of a single human glioblastoma multiforme surgically removed from a 44-year-old patient.Each specimen was rst measured with HRMAS 1 H MRS to determine tumor metabolites, then evaluated by quantitative histopathology.The concentrations of lactate and mobile lipids measured with HRMAS linearly re ected the percentage of tumor necrosis.Moreover, metabolic ratios of phosphorylcholine to choline correlated linearly with the percentage of the highly cellular malignant glioma.The quanti cation of tumor metabolic changes with HRMAS 1 H MRS, in conjunction with subsequent histopathology of the same tumor specimen, has the potential to further our knowledge of the biochemistry of tumor heterogeneity during development, and thus ultimately to improve our accuracy in diagnosing, characterizing, and evaluating tumor progression.
Lehmann's Medizinische Atlanten.
Journal: JAMA (1910)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Children with an increased lead burden. A screening and follow-up study
Authors: S. M. Pueschel
Journal: JAMA (1972)

In a house-to-house survey of an impoverished section of Boston, preschool children were studied in regard to lead poisoning with the use of a simple and inexpensive screening procedure based upon the analysis of lead in hair. Ninety-eight of 705 children screened in this fashion were found to have an increased lead burden. Chelation therapy was administered and environmental elimination of exposure to leadcontaining substances was initiated. Fifty-eight children with an increased lead burden underwent comprehensive study and 1 1/2 years later reexamination took place: minor neurological dysfunction and various forms of motor impairment were observed in 22% to 27% of the children during each evaluation. Initial psychological assessment revealed low average mental abilities in the majority of children and 1 1/2 years later a significant increase in certain areas of intellectual functioning was noted.
Health Effects of Smokeless Tobacco
Journal: JAMA (1986)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Ethics of Surgery
Journal: JAMA (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Leprosy Review, London
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Boxing-Reply
Authors: Ronald J. Ross
Journal: JAMA (1983)

<h3>In Reply.—</h3> Dr Engelberg is correct in stating that the sample was not random. As a matter of fact, in the United States at this time, there is no way to obtain a random selection of boxers, since boxers are not registered in a central registry and we must depend on obtaining data either from all boxers found or a selection thereof. In our case, we saw every boxer who agreed to be studied. We<i>do not agree</i>that "with such a sample, attempting any sort of statistical analysis is incorrect." The statistical analysis and conclusions pertain to our study only. The conclusions may or may not be applicable to boxers in general. We would like to point out, however, that our boxers had relatively few bouts, and we feel justified in assuming from the data that in those boxers having more bouts, worse CT scores would have been found.