tbuckley/cabot-search huggingface dataset:
Somatostatin receptors as markers for endocrine tumors
Authors: J. C. Reubi
Journal: JAMA (1987)

Endocrine tumors of the gastrointestinal tract are relatively rare neoplasias that secrete large amounts of peptide hormones such as insulin, glucagon, gastrin, or vasoactive intestinal peptide (VIP).<sup>1</sup>These substances are usually responsible for the distinct clinical features observed in patients with such tumors, named specifically insulinomas, glucagonomas, gastrinomas, VIPomas, or carcinoids. Although most are relatively slow-growing tumors, they may lead in early stages to dramatic symptoms such as hypoglycemia, gastric ulcerations, or watery diarrhea. Unfortunately, they are often difficult to localize precisely at that stage.<sup>2</sup> Somatostatin,<sup>3</sup>a tetradecapeptide that inhibits peptide hormone release in various sites such as the pituitary, the pancreas, and the gastrointestinal tract, has been shown recently to have beneficial effects when given chronically in the form of a stable non-degradable octapeptide analogue (SMS 201-995) in such gastrointestinal endocrine tumors.<sup>4,5</sup>It is likely that its therapeutic effect is due in part to inhibition
Society Proceedings
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Surgical Nursing
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pathology of the Central Nervous System.
Journal: Annals of Internal Medicine (1938)

310~~~~~~T H AAINMDCLASCAINJUNL[a.13 insulin.The following is taken verbatim as an ex- ample: "Today the general practitioner can start his patient upon diet and (PI) at the first visit, confident that reactions will not result during the following twenty-four hours.By return visits, daily, then every other day, later two times a week, and soon once a week, once in two weeks, and eventually once a month or even less often, he can easily, safely and efficiently treat his case, and at the same time avoid prolonged single seances for instruction which rob him of his time and overwhelm the patient with what he does not know.PZI par excellence is the family-doctor % type of insulin."It is obvious, therefore, that, except for the statement of the fact that in the treatment of diabetes there is now available a more effective form of insulin, this chapter serves no purpose.Aside from this one chapter, however, as with previous editions, no medical library in the English language can be, said to be complete without this authoritative work.
Cardiac Screening
Authors: Paul Zimmermann
Journal: Annals of Internal Medicine (2015)

Letters21 July 2015Cardiac ScreeningPaul Zimmermann, MDPaul Zimmermann, MDFrom South Carolina Heart Center, Camden, South Carolina.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L15-5112 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Chou's guideline (1) on cardiac screening recommends that asymptomatic adults not have resting electrocardiography (ECG). I find that this recommendation, in many instances, goes against the standard of care. Obtaining ECGs for screening is standard for athletes, who, by definition, are asymptomatic. The European Community (2) continues to find this intervention cost-effective.To argue against screening ECGs, Chou cites 2 articles showing their limited usefulness. Rubenstein and Greenfield (3) found that "the routine ECG has little value as a baseline." However, they state that 5% of patients were grouped into a class in which ECGs could be ...References1. Chou R; High Value Care Task Force of the American College of Physicians. Cardiac screening with electrocardiography, stress echocardiography, or myocardial perfusion imaging: advice for high-value care from the American College of Physicians. Ann Intern Med. 2015;162:438-47. [PMID: 25775317] doi:10.7326/M14-1225 LinkGoogle Scholar2. Myerburg RJ, Vetter VL. Electrocardiograms should be included in preparticipation screening of athletes. Circulation. 2007;116:2616-26. [PMID: 18040041] CrossrefMedlineGoogle Scholar3. Rubenstein LZ, Greenfield S. The baseline ECG in the evaluation of acute cardiac complaints. JAMA. 1980;244:2536-9. [PMID: 7431589] CrossrefMedlineGoogle Scholar4. Hoffman JR, Igarashi E. Influence of electrocardiographic findings on admission decisions in patients with acute chest pain. Am J Med. 1985;79:699-707. [PMID: 4073107] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Paul Zimmermann, MDAffiliations: From South Carolina Heart Center, Camden, South Carolina.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOf InterestForms.do?msNum=L15-0260. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoCardiac Screening With Electrocardiography, Stress Echocardiography, or Myocardial Perfusion Imaging: Advice for High-Value Care From the American College of Physicians Roger Chou and Cardiac Screening With Electrocardiography, Stress Echocardiography, or Myocardial Perfusion Imaging: Advice for High-Value Care From the American College of Physicians Roger Chou and Cardiac Screening Roger Chou Cardiac Screening Roger Chou Metrics 21 July 2015Volume 163, Issue 2Page: 151KeywordsConflicts of interestDisclosureElectrocardiographyIschemia ePublished: 21 July 2015 Issue Published: 21 July 2015 Copyright & PermissionsCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Professional Jobs Linked With ALS and Parkinson Disease Deaths
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Health care injustice fuels rage, riots
Authors: P. Cotton
Journal: JAMA (1992)

JUST HOURS before the now world-famous Rodney King verdict ignited this country's worst riots of this century, a meeting was held in Los Angeles, Calif, to address another perceived injustice. The days of violence that followed are reflecting a harsh light on what otherwise would have been obscure beginnings for the Los Angeles County Board of Supervisors' Task Force on Health Care Access, an earnest group with representation from virtually every pertinent interest group except underserved people and the minority physicians most likely to care for them. Access to health care, which is abysmal nationwide, is perhaps poorest in Los Angeles County. Fully 27% of the population is completely uninsured, and fewer and fewer physicians are taking patients covered by Medical, the state's program for the poor, because they say its meager payments do not meet even their overhead costs. "The safety net is torn to pieces. There is widespread
Abstract 1664: Comparison of RNA sequencing data generated from formalin-fixed, paraffin-embedded (FFPE) papillary thyroid carcinoma samples using different library preparation methods
Authors: Julie Dragon, Ramiro Barrantes, Jessica Hoffman, Scott Tighe
Journal: Cancer Research (2019)

Abstract Comparison of RNA sequencing data generated from formalin-fixed, paraffin-embedded (FFPE) papillary thyroid carcinoma samples using different library preparation methods. Julie Dragon, Ramiro Barrantes, Jessica Hoffman, and Scott Tighe. Genomics research requires a significant sample size to provide robust biological signal, leaving researchers clamoring for access to large sample sets. As this research continues to expand into the clinical arena, the demand to sequence RNA from banked tissue samples, such as formalin-fixed paraffin-embedded blocks, is unavoidable. Readily available, these samples represent a wealth of both patients and disease variation. However, recovering DNA and RNA from such samples can be challenging depending on age of the sample block and fixture protocols, which influence nucleic acid degradation and ultimately our ability to synthesize RNA-Seq libraries. To fulfill the need for increased recovery of quality reads, several manufacturers have developed solutions to address these challenges, including FFPE-specific extraction kits, as well as library synthesis and quality control reagents. In this study, we analyzed the quality and outcome of RNA-Seq data generated from RNA from two library synthesis kits applied to FFPE-derived human thyroid tumors with storage times from 4-12 years. The data processing pipeline included adaptor and poor quality base trimming (trimommatic), removal of rRNA reads (sortMeRNA), genomic alignment to hg19 (HiSat2), and read distribution and alignment quality assessment (RNASeqQC) (Adiconis and Levin, 2013). Differential expression was evaluated using DESeq2 (Love et al, 2014). Results indicated that of the reagents tested, it is possible to improve capture of the usable RNA data, and biological signal, with improved control of rRNA depletion and read duplication with newly developed library preparation kits specifically designed for FFPE samples. Moreover, our analysis illustrates some features of the tested synthesis kits that enable one to perform better for FFPE samples with highly varying quality, and quality metrics to consider when evaluating FFPE samples for sequencing. Citation Format: Julie Dragon, Ramiro Barrantes, Jessica Hoffman, Scott Tighe. Comparison of RNA sequencing data generated from formalin-fixed, paraffin-embedded (FFPE) papillary thyroid carcinoma samples using different library preparation methods [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1664.
Error in Visual Abstract
Journal: JAMA Oncology (2021)

Davendra P. S. Sohal, MD, MPH; Mai Duong, MS; Syed A. Ahmad, MD; Namita S. Gandhi, MD; M. Shaalan Beg, MD; Andrea Wang-Gillam, MD, PhD; James L. Wade III, MD; E. Gabriela Chiorean, MD; Katherine A. Guthrie, PhD; Andrew M. Lowy, MD; Philip A. Philip, MD, PhD; Howard S. Hochster, MD
Sudden infant death syndrome: will establishing risk factors spuriously reduce incidence?
Authors: R. Hanzlick
Journal: JAMA (1993)

<h3>In Reply.</h3> —Dr Relman is incorrect in claiming that the<i>NEJM</i>does not reveal anything about financial conflicts of interest to reviewers. Most conflicts of interest are inferred from the institutional affiliation or the funding source of the authors. While some journals mask this information from referees, the<i>NEJM</i>includes it with manuscripts sent for review. More to the point, the decision to publish is not made by reviewers, but by editors. The<i>NEJM</i>policy requires that authors present all information about potential conflicts of interest (including any information that might not be apparent from institutional affiliation and funding source) when submitting a manuscript. Since this information could be solicited after manuscripts are accepted for publication, one can only suppose that the editors require it before the review so that they can take it into account in making their decision about publication. If the<i>NEJM</i>editors wanted to judge submissions
Clinical Hematology
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Intensive Care
Authors: Edward B. J. Winslow
Journal: JAMA (1975)

<h3>Intensive Care,</h3> by Åke Wåhlin, Lars Westermark, and Ansje van der Vliet, 323 pp, 74 illus, $20, New York, Wiley, 1974. Both of these books were written by anesthesiologists and were intended for junior house officers, medical students, and nurses. Gerson's book, which originated in Great Britain, was first published in 1973. The other book, from Sweden, is based on a 1972 revision of a book that first appeared in 1968. Both books suffer from the fact that they are written for a European audience and many of the techniques and drugs mentioned by the authors are either unfamiliar trademarks or drugs that are not in use in the United States. In addition, neither book, because of multiple authorship in one and the early date of publication in the other, discusses the techniques used in intensive care in the United States. In neither book is there any description or discussion
203P Molecular analysis of predictive biomarkers-KRAS, BRAF, NRAS and PIK3CA in colon cancer and correlation of clinico-pathological features with mutation profiling and therapeutic response in Indian patient cohort
Authors: H.A. Patil, S. Gada Saxena, C. Barrow, R.K. Kanwar, J.R. Kanwar, A. Kapat
Journal: Annals of Oncology (2016)
Oesophageal function in diabetes.
Journal: BMJ (1967)

Thank you for your interest in spreading the word about The BMJ.NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address. Username * Your Email * Send To * You are going to email the following Oesophageal function in diabetes. Your Personal Message CAPTCHA This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Use of Therapeutic Agents in Specific And Systemic Viral Diseases Discussed
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Issue Information ‐ TOC
Authors: Zaid Amso, Jillian Cornish, Margaret Brimble, Paola Vitale, Andrea Panella, Antonio Scilimati, Maria Perrone, Wing Yan, So Po, Sing Leung, Enas Malik, Christa Üller, J Van Den Bossche, F Lardon, V Deschoolmeester, I De Pauw, J Vermorken, P Specenier, P Pauwels, M Peeters, A Wouters, Joe Tomaszewski
Journal: Medicinal Research Reviews (2016)

Description of the cover image: Schematic representation of the stabilization of the cleavage complex by anthracyclines and related drugs. Medicinal Research Reviews: Aims and ScopeThe journal publishes timely critical reviews of topics related to medicinal research, broadly defined, to which the authors have made significant contributions.Appropriate topics include, but are not limited to, the underlying pathophysiology of important diseases and disease vectors; therapeutic approaches to the treatment of various diseases; the properties of molecular targets for therapeutic agents; important new methodologies facilitating the search for therapies; genomics and proteomics; structure-activity correlations of drug series; the development of new imaging and diagnostic tools; drug metabolism; drug delivery; and chemical, pharmacological, pharmacokinetic, pharmacodynamic, and clinical characteristics of important drugs.Reviews are mainly solicited by the editors; however, voluntary contributions are also encouraged.In the latter case, potential authors are asked to contact the Editor-in-Chief with an outline before beginning to write in order to avoid duplication of effort and to ensure suitability of the topic and the level of coverage.
Organizations of Medical Interest
Journal: JAMA (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Literary style in American medical writing. A historica view
Authors: J. B. Blake
Journal: JAMA (1971)

In medical writing, literary style for years has been getting steadily worse. Such at least is the opinion often expressed and apparently believed by those who would exhort authors to do better. A historian cannot be expected to point ways out of the present bog (if, in fact, it exists), for this is the prophet's job. Nor should he be expected to present a critique of the literary style found in the mass of current material glutting our libraries. Perhaps, however, he may properly explore the assertion, or the assumption, that the literary style of medical writing is "getting worse." An examination of what critics have said in the past may help to bring perspective to the present. For an idea of what leading medical men thought about American medical literature some 120 years ago, one can turn to the succession of reports by the Committee on Medical Literature published