INFLUENZA
Authors: FRANK L.  HORSFALL JR.
Journal: Annals of Internal Medicine (1941)

Article1 November 1941INFLUENZAFRANK L. HORSFALL JR., M.D.FRANK L. HORSFALL JR., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-15-5-811 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptInvestigations of influenza have been beset with serious difficulties since first they were begun. Acute upper respiratory diseases tend to resemble each other very closely and, as is well known, their classification on clinical grounds has not been very successful. One of the chief difficulties is the lack of definite objective signs, except for fever and minor alterations in the appearance of the mucosa of the upper respiratory tract. Unfortunately, there is no sharp line between the symptomatology of a severe common cold, sporadic grippe, and influenza. The manifestations of these symptom-complexes shade imperceptibly one into another, and the difficulties...References1. FRANCISMAGILLBECKRICKARD TTPMDER: Studies with human influenza virus during the influenza epidemic of 1936-1937, Jr. Am. Med. Assoc., 1937, cix, 566-569. CrossrefGoogle Scholar2. STUART-HARRISANDREWESSMITH CHCHW: A study of epidemic influenza: with special reference to the 1936-7 epidemic, Med. Research Council, Special Report Series No. 228, 1938, His Majesty's Stationery Office, London. Google Scholar3. FRANCIS T: Epidemic influenza: Studies in clinical epidemiology, ANN. INT. MED., 1939, xiii, 915-922. Google Scholar4. HORSFALLHAHNRICKARD FLRGER: Four recent influenza epidemics: An experimental study, Jr. Clin. Invest., 1940, xix, 379-392. CrossrefGoogle Scholar5. STUART-HARRISSMITHANDREWES CHWCH: The influenza epidemic of January-March, 1939, Lancet, 1940, i, 205-225. CrossrefGoogle Scholar6. TAYLOR RM: Detection of human influenza virus in throat washings by immunity response in Syrian hamster (Cricetus auratus), Proc. Soc. Exper. Biol. and Med., 1940, xliii, 541-542. CrossrefGoogle Scholar7. SMITHANDREWESLAIDLAW WCHPP: A virus obtained from influenza patients, Lancet, 1933, ii, 66-73. CrossrefGoogle Scholar8. MAGILL TP: A virus from cases of influenza-like upper respiratory infection, Proc. Soc. Exper. Biol. and Med., 1940, xlv, 162-164. CrossrefGoogle Scholar9. FRANCIS T: A new type of virus from epidemic influenza, Science, 1940, xcii, 405-408. CrossrefGoogle Scholar10. RICKARDLENNETTEHORSFALL EREHFL: A comprehensive study of influenza in a rural community, U. S. Pub. Health Rep., 1940, lv, 2146-2167. CrossrefGoogle Scholar11. FRANCISMAGILLRICKARDBECK TTPERMD: Etiological and serological studies in epidemic influenza, Am. Jr. Pub. Health, 1937, xxvii, 1141-1159. CrossrefGoogle Scholar12. HORSFALL FL: Present status of knowledge concerning influenza, Am. Jr. Pub. Health, 1940, xxx, 1302-1310. CrossrefGoogle Scholar13. ANDREWESSMITH CHW: Influenza: further experiments on active immunization of mice, Brit. Jr. Exper. Path., 1937, xviii, 43-55. Google Scholar14. FRANCISMAGILL TTP: The antibody response of human subjects vaccinated with the virus of human influenza, Jr. Exper. Med., 1937, lxv, 251-259. CrossrefGoogle Scholar15. STOKESCHENOWETHWALTZGLADENSHAW JADADRGDR: Results of immunization by means of active virus of human influenza, Jr. Clin. Invest., 1937, xvi, 237-243. CrossrefGoogle Scholar16. STOKESMCGUINNESSLANGNORSHAW JACPHDR: Vaccination against epidemic influenza with active virus of human influenza, Am. Jr. Med. Sci., 1937, cxciv, 757-768. CrossrefGoogle Scholar17. TAYLORDREGUSS RMM: An experiment in immunization against influenza with a formaldehyde-inactivated virus, Am. Jr. Hyg., 1940, xxxi, 31-35. Google Scholar18. HORSFALLLENNETTERICKARD FLEHER: A complex vaccine against influenza A virus. Quantitative analysis of the antibody response produced in man, Jr. Exper. Med., 1941, lxxiii, 335-355. CrossrefGoogle Scholar19. HORSFALLLENNETTE FLEH: A complex vaccine effective against different strains of influenza virus, Science, 1940, xci, 492-494. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Read at the Boston meeting of the American College of Physicians, April 25, 1941.From the Laboratories of the International Health Division of The Rockefeller Foundation, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPRIMARY ATYPICAL PNEUMONIAXLII Medical Research and War Problems 1 November 1941Volume 15, Issue 5Page: 811-816KeywordsCommon coldFeversGlobal healthMucous membranesPulmonary diseasesRespiratory system ePublished: 1 December 2008 Issue Published: 1 November 1941 PDF downloadLoading ...