tbuckley/cabot-search huggingface dataset:
Effects of Corn Oil and Benzyl Acetate on Number and Size of Azaserine-Induced Foci in the Pancreas of LEW and F344 Rats
Authors: Daniel S. Longnecker, B. D. Roebuck, Thomas J. Curphey, Evelyne Lhoste, Charles I. Coon, Denise MacMillan
Journal: Environmental Health Perspectives (1986)

The response of LEW and F344 strain rats to the pancreatic carcinogen azaserine was compared using the size and number of azaserine-induced acidophilic acinar cell foci and nodules as parameters in a 4-month experiment. A second experiment compared the effect of corn oil intake by gavage and dietary routes on the growth of azaserine-induced pancreatic lesions in LEW rats. A third experiment tested the activity of benzyl acetate in regard to its ability to induce acinar cell foci or to promote the growth of such foci in azaserine-treated rats. The results showed that equivalent doses of azaserine induce two to seven times more foci in LEW than in F344 rats, and that LEW rats have a higher incidence of "spontaneous" foci than F344 rats. Azaserine-treated LEW rats that were given 5 mL corn oil/kg body weight 5 days per week by gavage developed more acinar cell foci than rats fed a basal diet (chow). Addition of an equivalent amount of corn oil to chow had a similar effect of enhancing the development of foci. Rats of neither strain developed acinar cell foci when benzyl acetate was given by gavage or in the diet nor was there evidence that benzyl acetate has a significant effect on the development of foci in azaserine-treated rats. These studies also demonstrate that the azaserine/rat model of pancreatic carcinogenesis which was developed in LEW rats can be adapted for use with F344 rats.
Der dialektische Materialismus und die klinische Medizin.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE THYROID AND THE REPRODUCTIVE FUNCTIONS.
Journal: JAMA (1905)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fatal Heat Stroke
Authors: Charles D. Graber
Journal: JAMA (1971)

<i>Fatal heat stroke occurred in a patient and was complicated by shock, septicemia, anuria, and consumption coagulopathy. The patient also developed endotoxemia, hypocomplementemia, hypoimmunoglobulinemia, and elevated serum lysozyme, which were quantified by immunologic tests. Autopsy findings were consistent with those seen in experimental endotoxic shock and were characterized by numerous fibrin thrombi in arterioles. It may be advisable to perform the</i>Limulus<i>lysate test for the determination of serum endotoxin levels in all cases of heat stroke to obtain new information about the clinical course of such patients and to elucidate the role of circulating endotoxin as a potential fatal mechanism</i>.
Learning Disabilities
Authors: Marjorie C. Meehan
Journal: JAMA (1969)

When a child learns poorly in school, he is often called lazy, stupid, or stubborn. A physician, if consulted, will check for visual or hearing defects, physical illness, and mental retardation. Finding none of these, he may advise the parents to use old-fashioned discipline, consult a psychiatrist, or try a different school. Recently some neurologists and pediatricians are recognizing that many children have specific learning difficulties, probably related to inconspicuous neurological defects. Typically, the child with learning defects is considered normal until he enters school, although his parents may have noted unusual restlessness and late talking. When he starts school, his troubles begin. He doesn't learn to read and write. Instead of receiving the praise and approval his classmates get, he is scolded, made to feel that he is "bad," "dumb," or both. Not receiving recognition for academic success, he engages in mischievous, attention-getting behavior. This combined with his restlessness
Skin Tests in Bacterial and Viral Diseases
Authors: Lewis W. Kane
Journal: New England Journal of Medicine (1945)

Skin Tests Employing Bacterial Toxins Schick Test In 1908, Schick85 showed that the toxin of the diphtheria bacillus is capable of eliciting dermal reactions in certain persons. His subsequent publications86 , 87 announced that this test could be used as an index of immunity or susceptibility to diphtheria. His experiments indicated that a negative intracutaneous reaction usually means a high enough level of antitoxin to protect against the disease. The test dose of toxin was originally defined by Schick on an empirical basis as 1/50 of a guinea-pig M. L. D. (minimal lethal dose). This level was selected by him because he . . .
Book Review Skin Diseases and Nutrition (Including the Dermatoses of Children) . By Erich Urbach, M.D. Authorized English Translation by Frederick Rehm Schmidt, M.D. (55 Illustrations, 8 diagrams, and 10 tables.) Wilhelm Maudrich, Publisher, Vienna, 1932. Price $7.00, postage free.
Journal: New England Journal of Medicine (1933)
Tooth avulsion
Authors: Isabelle Moran, Martin James, William Cook, Michael Perry
Journal: BMJ (2016)

#### What you need to know A 7 year old boy has tripped in the playground and knocked his front tooth out. He attends the emergency department with his mother, who has the tooth in her hand. He is stable and has no other injuries of concern. Permanent dental problems can be avoided by taking a simple dental history and doing a basic examination. The main question is whether re-implantation of the tooth is appropriate. Was this a primary (baby) tooth or a permanent (adult) tooth? At 6-8 years of age, the primary central incisors have usually fallen out and the larger, permanent incisors have erupted (fig 1⇓). The associated with avulsion injury of a primary tooth, such as disturbances in eruption and appearance of the developing permanent teeth, can be increased if a primary tooth is re-implanted.1 This is not advised, and monitoring of permanent tooth eruption is essential following injury.2 3 Fig 1 Diagram highlighting difference in size between primary and permanent incisors. The primary central incisor is approximately 16 mm in length, two thirds the size of its permanent successor ### History
Reexamination of London, England, Mortality in Relation to Exposure to Acidic Aerosols during 1963-1972 Winters
Authors: George D. Thurston, Kazuhiko Ito, Morton Lippmann, Carl Hayes
Journal: Environmental Health Perspectives (1989)

Air pollution epidemiology since the 1950s has been able to demonstrate that increases in daily mortality in London, England, were associated with elevated concentrations of index air pollutants, i.e., British Smoke (BS) and sulfur dioxide (SO2). In this work, we reanalyze that portion of the 1958-1972 winter mortality-pollution record for which daily direct acid aerosol measurements were made at a central site in London (St. Bartholomew's Medical College). The purposes of these exploratory analyses are to examine the dataset for indications of a relationship between acid aerosol pollution and human mortality and to compare any noted associations with those for other pollution variables. It is found that the log of acid aerosol concentrations is more strongly associated with raw total mortality in bivariate analyses than is BS or SO2, despite the fact that acid data are available from only one central site (versus seven disperse sites for BS and SO2). The logarithmic nature of the exposure side of the H2SO4-mortality relationship implies a saturation model of pollution effects, possibly due to multiday pollution harvesting influences on a susceptible subpopulation. Moreover, mortality-pollution cross-correlation analyses indicate that mortality effects usually follow pollution in time, supporting a causal relationship between the two. The apparent advantage of H2SO4 over BS in predicting total raw mortality is consistent with the hypothesis that it is the portion of particulate mass of greater health significance and may also allow the development of London mortality results which are more easily transferable to other environments than is the case for existing BS results.
Augmentation of Murine Vasculogenesis by Injected Human Hematopoietic Stem Cells in Response to Ischemia Follows Early Activation of Innate Immune Response
Authors: Nicholas Greco, Mathew Lawrence Lesniewski, Marcie Finney, Laura Fanning, Margie Kozik, Matthew Joseph, Jonathan Goldberg, Peter Haviernik, Pingfu Fu, Vince Pompili, Mary J. Laughlin
Journal: Blood (2008)
Effects of PCB Exposure on Biochemical and Hematological Findings in Capacitor Workers
Authors: Richard W. Lawton, Marie R. Ross, Joseph Feingold, John F. Brown
Journal: Environmental Health Perspectives (1985)

Certain former operations in capacitor manufacturing resulted in extensive direct contact of the workers with electrical grade polychlorinated biphenyls (PCBs). A study group of 194 such individuals, all exposed to Aroclor 1016 and many previously exposed to Aroclors 1242 and/or 1254, was examined before (1976) and after (1979) discontinuance of PCB use in the operations (1977). At the two examinations, the approximate geometric mean serum levels (in ppb) and 5 to 95% ranges were for lower PCBs (LPCB), 363 (57-2270) and 68 (12-392); and for higher PCBs (HPCB), 30 (6-142) and 19 (4-108), respectively. The statistical associations among 42 measured clinical chemical and hematological parameters, five different measures of PCB exposure, and seven confounding variables observed in the two examinations were determined by three regression procedures. Similar regressions were performed with DDE, which was present at background levels. The principal statistical findings were a depression in serum bilirubin and elevations in serum GGTP and lymphocyte levels at the time of the first examination, and only an elevation in monocytes at the second. Appraisal of the results suggested an induction of microsomal enzymes which appeared to be subsiding after the cessation of direct exposure to PCBs. The statistical association between serum levels of PCBs and lipids reported by others was confirmed, but shown to be explained by the partitioning behavior of PCB in the body, rather than to changes in liver function. No evidence for health impairment related to PCBs was found, despite the high serum levels of PCBs in the study population.
Editorial Board
Authors: Rhiannon Macrae, Milka Kostic, Basil Nyaku, Ria Otten, Patrick Scheffmann, K Anderson, New York, Usa Clark, G Fink, S Gasser, Switzerland Goldstein, L Guarente, Y Hayashizaki, S Henikoff, J Hodgkin, H Horvitz, Usa Cambridge, E Hurst, E Meyerowitz, S Moreno
Journal: Trends in Genetics (2013)
Paraparesis with Incontinence of Bowel and Bladder. A Syndrome of Bilateral Subdural Hematomas
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Physician Recruitment Advertising
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Die Brücke: Klinische Bilder in sechs Sprachen. Ein Hilfsbuch für Ärzte bei der Behandlung fremdsprachiger Patienten
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Profits from drugs.
Journal: BMJ (1973)

nine.The secretion of thyroxine (T-4) is normal, though later it may become excessive.It is thought that this dis- ordered pattern of secretion may be due, in some cases at least, to iodine deficiency.The patient is clinically thyrotoxic, but the conventional tests of thyroid function are normal.A firm diagnosis can be made only by direct measurement of T-3 and TA in the plasma.These techniques are not yet generally available, but a failure to suppress uptake of iodine-131 by the T-3 test4 will support the diagnosis.
Psychosurgery
Authors: Milton Greenblatt, Paul Graves Myerson
Journal: New England Journal of Medicine (1949)

AN EDITORIAL1 in 1940 referred to "radically wrong," "meddlesome surgery," which was a "violation of the Hippocratic oath." An opposing view was expressed by Fiamberti2: "In the present state of affairs, if some are critical about lack of caution in therapy, it is on the other hand deplorable and inexcusable to remain apathetic, with folded hands, content with learned lucubrations upon Symptomatologic minutiae or upon psychopathic curiosities, or, even worse, not even doing that." The first opinion is written by a man who fears an indiscriminate cutting of lobes and hemispheres by unconscionable surgeons, and the second by one . . .
Potential impact of health system reform on medical education. Task Force on Health Systems and Medical Education
Journal: JAMA (1993)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum for the Research Article: “Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys” by Y. Xiong, K. Walker, X. Min, C. Hale, T. Tran, R. Komorowski, J. Yang, J. Davda, N. Nuanmanee, D. Kemp, X. Wang, H. Liu, S. Miller, K. J. Lee, Z. Wang, M. M. Véniant
Journal: Science Translational Medicine (2018)
Lectures on Surgery to Nurses.
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Care of the Aged
Journal: JAMA (2017)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
ALIMENTARY PROTECTION AGAINST HEMOLYTIC STREPTOCOCCI
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal