tbuckley/cabot-search huggingface dataset:
Screening for Diabetes
Journal: Diabetes Care (1990)

Screening for Diabetes Diabetes mellitus is characterized by a lack of insulin secretion and/or increased cellular resistance to insulin resulting in hyperglycemia and other metabolic disturbances.Symptoms of diabetes can include excessive thirst and hunger, frequent urination, weight loss, blurred vision, and recurrent infections; however, the disease is often asymptomatic in its early stages.The disease is associated with severe neurological, cardiovascular, ocular, and renal complications.An estimated 6 million undiagnosed cases exist among adults in the United States.This document presents recommendations for diabetes screening activities.It provides guidance to those who are contemplating or engaged in activities to identify individuals with a significant probability of having diabetes mellitus. TYPES OF DIABETESDiabetes is a group of disease states that may be classified as follows.Insulin-dependent diabetes mellitus (IDDM).IDDM usually, although not always, appears before the age of 30 yr and has an abrupt onset of symptoms that requires prompt medical treatment.Approximately 10% of all people diagnosed with diabetes have this type.Because of the acute nature of its symptoms, IDDM usually does not remain undetected for very long.This fact, combined with its low incidence, makes it unlikely that any case of IDDM will be uncovered by any type of screen-
Service in strict islamic nation removes alcohol, other drugs from major problem list
Authors: P. Gunby
Journal: JAMA (1991)

SAUDI ARABIA, where many of the US troops in Operation Desert Storm are located, forbids the importation of liquor or other drugs of potential abuse. Probably as a result of this and other factors (including the fact that the allvolunteer US armed forces are much more drug free than a few years ago), US military provost marshals have not encountered the problems associated with alcohol and other drugs that plagued their predecessors during Southeast Asian combat of the 1960s and early 1970s. In addition to relatively few crimes against persons or property by US military people in this theater of operation, driving while under the influence of alcohol or other drugs also has not been a problem. <h3>Strong Civil Penalties</h3> The US Information Service in Dhahran says that "a charge of marijuana possession and/or importation [in Saudi Arabia] may yield a prison sentence of several years, depending on the amount
Rubella (German Measles)
Authors: Conrad Wesselhoeft
Journal: New England Journal of Medicine (1947)

Flibbertigibbet In folklore congenital deformities were considered to be the result of extrinsic influences on the pregnant mother. Something she saw or some experience she underwent was thought to bring about the defect in her child. At the time when there was a general belief in witchcraft and calamities were ascribed to demoniacal influence, congenital deformities were supposed to be the result of the casting of a spell on the pregnant mother. King Lear contains the following reference: "That foul fiend, Flibbertigibbet. He begins at curfew, and walks till the first cock. He gives the web and the pin, squints . . .
IRRADIATION OF THE HUMAN FETAL THYROID GLAND FROM I131 FALLOUT
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Letter Regarding Article by Arnlov et al, “Low-Grade Albuminuria and Incidence of Cardiovascular Disease Events in Nonhypertensive and Nondiabetic Individuals”
Authors: Folkert W. Asselbergs, P. van der Harst, Wiek H. van Gilst
Journal: Circulation (2006)

UACR.In model 1, UACR was related positively to age, female sex, systolic blood pressure, fasting blood sugar, and smoking but was inversely related to body mass index.Similar relations were observed for model 2. The ratio of total to HDL cholesterol was not related to UACR in any of the models that we examined.In summary, we observed that UACR was related to select cardiovascular risk factors in both our healthier subsample and in our larger, more general study sample (consistent with other reports 2-6 ).Our observations concur with those of other investigators who have reported weaker relations of cardiovascular risk factors to UACR in low-risk samples compared with samples including higher-risk individuals.
Final results of a phase II trial of trabectedin (T) in patients with hormone receptor-positive, HER2-negative advanced breast cancer, according to xeroderma pigmentosum gene (XPG) expression.
Authors: Ahmad Awada, Javier Cortes, Miguel Martin, Philippe Aftimos, Mafalda Oliveira, Marc Espie, Pilar Lardelli, Sonia Extremera, Carmen Maria Kahatt, Suzette Delaloge
Journal: Journal of Clinical Oncology (2013)

547 Background: Hormone receptor (HR)-positive, HER2-negative metastatic breast cancer (BC) is currently associated with 3-4 years survival and, after ≥2 relapses, therapeutic approaches are reduced. XPG expression is frequently modified in BC. T forms cytotoxic complexes with XPG inducing apoptosis, thus, the inhibitory effects of T may depend on XPG presence. In fact, a better response to T in BC pts with XPG RNA overexpression has been observed. Methods: Pts withHR positive, HER2 negative advanced BC, pretreated with anthracyclines and/or taxanes, who had progressed after 2-5 chemotherapy lines, were stratified according to their XPG expression from paraffin embedded tumor samples, to stratum A (XPG high [&gt;3]) or to stratum B (XPG low [≤3]) (threshold was selected from median XPG expression values observed in a previous trial) and treated with T (1.3 mg/m 2 in 3-hour iv infusion every 3 weeks). Primary endpoint: to evaluate the efficacy of T as progression free survival rate at 4 months (PFS4) according to XPG expression. Secondary endpoints: Comparison of PFS, overall response rate, duration of response, overall survival and safety in XPG high and XPG low pts. Statistical methods: A 2-stage design was chosen: at a 1st stage, 20 pts were enrolled in each stratum. A futility analysis (O’Brien Fleming boundary) based on the primary endpoint was done once 40 evaluable pts were recruited. If ≥ 7 out of 20 pts achieved PFS4, recruitment would continue to a maximum of 50 pts per stratum. Results: 44 pts (21 XPG high and 23 XPG low) were enrolled from three countries and five centers. Efficacy is shown in the Table. Most frequent AEs were nausea (54%) and fatigue (70%). ALT increase G4 occurred in 7% of pts and neutropenia G4 in 28%. Conclusions: Trabectedin showed modest activity in advanced HR-positive, HER2-negative BC previously treated with anthracyclines and taxanes, with an acceptable safety profile. XPG does not seem to be a predictor of outcome to T treatment in this patient population. Clinical trial information: 2010-022968-13. [Table: see text]
Medical care for indigent and culturally displaced obstetrical patients and their newborns. Committee on Maternal, Adolescent, and Child Health. Council on Scientific Affairs
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mortality Study of Workers in 1,3-Butadiene Production Units Identified from a Chemical Workers Cohort
Authors: Elizabeth M. Ward, John M. Fajen, Avima M. Ruder, Robert A. Rinsky, William E. Halperin, Cindy A. Fessler-Flesch
Journal: Environmental Health Perspectives (1995)

The International Agency for Research on Cancer has given the designations of "sufficient evidence" of carcinogenicity of 1,3-butadiene in experimental animals and "limited evidence" of carcinogenicity in humans. To investigate the carcinogenic effect in humans, we conducted a cohort mortality study among 364 men who were assigned to any of three 1,3-butadiene production units located within several chemical plants in the Kanawha Valley of West Virginia, including 277 men employed in a U.S. Rubber Reserve Plant which operated during World War II. The butadiene production units included in this study were selected from an index developed by the Union Carbide Corporation, which listed for each chemical production unit within their South Charleston, West Virginia and Institute, West Virginia, plants all products, by-products, and reactants. Departments included in the study were those where butadiene was a primary product and neither benzene nor ethylene oxide was present. A total of 185 deaths were observed; the standardized mortality ratio (SMR) for all causes of death was 91, reflecting lower mortality among the study population than the U.S. population. The study found a significantly elevated standardized mortality ratio (SMR) for lymphosarcoma and reticulosarcoma based on four observed cases (SMR = 577; 95% CI = 157-1480), which persisted in an analysis using county referent rates. An excess of lymphosarcoma and reticulosarcoma among all workers and among workers with routine exposure to 1,3-butadiene was also observed in the only other cohort of 1,3-butadiene production workers previously studied.(ABSTRACT TRUNCATED AT 250 WORDS)
SMBE Editors and Council
Authors: Walter Fitch, Masatoshi Nei, Marcy Uyenoyama, Elizabeth Raffaele, G Golding, Richard Lewontin, Howard Ochman, Ken Wolfe, Charles Aquadro, Jody Hey, Manyuan Long, John Archibald, Dan Graur, Robin Bush, Soojin Yi
Journal: Molecular Biology and Evolution (2011)
Journal Corrections
Authors: Stanley Leong, David Byrd, Alistair Cochran, Alexander Eggermont, Kelly Mcmasters, Martin Mihm, Keith Flaherty, Donald Morton, K Sondak, H Lee
Journal: Journal of Clinical Oncology (2011)

In the sidebar and in the last sentence of the Introduction section, the QUASAR trial number was given as ISRCTN82375366, whereas it should have been given as ISRCTN82375386.The following acknowledgement was inadvertently omitted: "WethankEmmaTinkler-Hundalforhersignificantcontributionsto the preparation of clinical trial material used within the study."
THE TENDENCY TO URBAN CONCENTRATION.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Books Received
Journal: JNCI Journal of the National Cancer Institute (1964)

Journal Article Books Received Get access Normal growth and cancer. By Medes Grace and Reimann Stanley P.. 268 p., $8.00. The J. B. Lippincott Company, East Washington Square, Philadelphia, Pennsylvania, 1963. Handbook of medical sociology. Edited by Freeman Howard E., Levine Sol, and Reeder Leo G.. 602 p., $11.00. Prentice-Hall, Inc., Englewood Cliffs, New Jersey, 1963. The Cytologic diagnosis of cancer. By Graham Ruth M.. 387 p., $14.00. W. B. Saunders Company, 218 West Washington Square, Philadelphia, Pennsylvania, 1963. Mechanisms of immunological tolerance. Edited by Hasek M., Lengerová A., and Voktiskova M.. 544 p., $18.00. Academic Press Inc., 111 Fifth Avenue, New York, New York, 1963. Pathology of the upper respiratory tract. By Rewell R.E.. 283 p., $8.50. The Williams & Wilkins Company, 428 East Preston Street, Baltimore, Maryland, 1963. The treatment of malignant disease by radiotherapy. By Paterson Ralston. 556 p., $15.50. The Williams & Wilkins Company, 428 East Preston Street, Baltimore, Maryland, 1963. Clinical laboratory diagnosis. By Levinson Samuel A. and MacFate Robert P.. 1274 p., $15.00. Lea & Febiger, 600 Washington Square, Philadelphia, Pennsylvania, 1961. The Swedish Cancer Society year book 1960–1962. Edited by Bergstrand Hilding. 511 p. Almquist & Wiksell, Stockholm, Sweden, 1963. Chemistry of chelation in cancer. By Furst Arthur. 143 p., $7.50. Charles C Thomas, 301–327 East Lawrence Avenue, Springfield, Illinois, 1963. Cancer progress—1963. Edited by Raven Ronald W.. 268 p., $12.00. Butterworth Inc., 7235 Wisconsin Avenue, Washington, D.C., 1963. JNCI: Journal of the National Cancer Institute, Volume 32, Issue 2, February 1964, Page 534, https://doi.org/10.1093/jnci/32.2.534 Published: 01 February 1964
The Human Metallothionein Gene Family: Structure and Expression
Authors: Michael Karin, Robert I. Richards
Journal: Environmental Health Perspectives (1984)

Metallothioneins (MTs) are encoded by a multigene family in man. We have isolated those genes and analyzed the structure of some of them. The MT-II variant is encoded by a single functional gene: MT-IIA. The MT-IIB gene is a processed pseudogene derived from a reverse transcript of MT-II mRNA. On the other hand, the MT-I class of variants are encoded by a large number of genes, arranged in tandem. The MT-IIA and the MT-IA genes show a differential response to glucocorticoid hormones and heavy metals, yet they are both expressed in primary human fibroblasts and in HeLa cells. Expression of both of those genes, in high level after transfer on bovine papilloma virus vectors, leads to increased resistance of the host cells to cadmium-induced toxicity.
Bacteriologic features of chronic sinusitis in children
Authors: I. Brook
Journal: JAMA (1981)

Aspiration of chronically inflamed sinuses was aseptically performed in 40 children. The median age was 11 years (range, 6 to 16 years). The sinuses were the maxillary (15 cases), ethmoid (13), and frontal (seven). Pansinusitis was present in five patients. All aspirates were cultured for aerobes and anaerobes and yielded bacterial growth in 37 patients. A total of 121 isolates (97 anaerobic and 24 aerobic) were recovered, accounting for 2.7 anaerobes and 0.6 aerobes per specimen. Anaerobic organisms were recovered from all 37 culture-positive specimens, and in 14 cases (38%) they were mixed with aerobic organisms. The predominant anaerobic organisms were Bacteroides species (36), anaerobic Gram-positive cocci (28), and<i>Fusobacterium</i>species (13). The predominant aerobic isolates were α-hemolytic streptococci (seven),<i>Staphylococcus aureus</i>(seven), and<i>Haemophilus</i>species (four). These findings indicate the major role of anaerobic organisms in the polymicrobial cause of long-term sinusitis in children. (<i>JAMA</i>1981;246:967-969)
Complete Transposition of the Great Vessels: Importance of Septal Defects and Patent Ductus Arteriosus
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Changes
Authors: George N. Braman
Journal: Annals of Internal Medicine (2008)

Ad Libitum15 July 2008ChangesGeorge N. Braman, MDGeorge N. Braman, MDFrom Bronx, NY 10471.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-149-2-200807150-00013 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail about this hour, what changes sweep the earth,... Author, Article, and Disclosure InformationAffiliations: From Bronx, NY 10471.Current Author Address: George N. Braman, MD, 5903 Liebig Avenue, Bronx, NY 10471. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 15 July 2008Volume 149, Issue 2Page: 143KeywordsHeart ePublished: 15 July 2008 Issue Published: 15 July 2008 Copyright & PermissionsCopyright © 2008 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Availability of Injury Mortality Atlas of the United States, 1979-1987
Journal: JAMA (1991)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correction: Enteropathy induced by non-steroidal anti-inflammatory drugs
Journal: BMJ (1989)

since transurethral resection two weeks before.Is this appreciable reduction in morbidity?Certainly he did not have to stay long in hospital, but who is to say that the current operative technique is more agreeable than open prostatectomy-it is done by the same surgeons, registrars, and house officers with intact prostates, who assert that retrograde ejaculation elicits the same sensation as normal.And did one of them consider asking me whether I wanted another child before thev rendered mv husband infertile?Nomy consent was never sought.He was on the
Reports of Societies
Journal: BMJ (1901)

only one, pyranaid opening in the pelvis.The appearances on microscopical examination were those of a fairly healthy kidney, the glomeruli, as a whole, being large and well developed, aiid containing blood in the capillaries; in one or two cases they showed a slightly hyaline appearance.The convoluted tubules were large and well developed, the epi- thelium being cloudy and granular in parts; the tubuli recti were distinct and well marked.The left kidney weighed 6 ozs., was large and pale; the capsule was adherent, and caused some decortication on stripping; the cortex was of average thickness but very pale.As regards the other organs, the chief points of interest :were some rusty staining of the dura mater at the base in the right temporal region; the pia was thickened and the brain substance was very firm.There was some atheroma about the aorta and slight disease of the heart; the lungs showed gangrene and broncho-pneumonia, and the liver was slightly fatty, and with patches of waxy change.