tbuckley/cabot-search huggingface dataset:
Wrestling and Weight Control
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Seniority Pay
Authors: B. R. Wheeler
Journal: BMJ (1964)

<h3>Introduction</h3> Policies raising the minimum age of sale of tobacco products to 21 (T21) proliferated at state and local levels across the USA before a federal policy was adopted. Evidence of the effectiveness of these policies is building and lags implementation. This study exploits demographic patterns of cigarette brand purchasing to evaluate the effectiveness of T21. <h3>Methods</h3> To capture the effect of T21 implementation on cigarette sales, we used universal product code-level data from Nielsen Scantrack data covering January 2015 to October 2019. We used the 2015 to 2018 National Survey on Drug Use and Health to identify cigarette brands where smokers under 21 comprised a disproportionately high (young) and low (old) share of consumption. We fit fixed-effects linear regressions in Nielsen designated market areas to test if sales of young or old cigarette brands were changed by T21. Unadjusted models controlled for time and T21 implementation date. Adjusted models controlled for price, seasonality and unemployment. A permutation test of 5000 randomised placebo T21 policies were fit to determine how well the true date of implementation fit sales data stratified by brand group. <h3>Results</h3> Sales of disproportionately young brands declined after T21 implementation. T21 policy implementation dates fit disproportionately young brand sales trends better than 99% of adjusted randomised placebo models. T21 implementation fit disproportionately old brand sales trends better than just 1% of adjusted randomised placebo models. <h3>Conclusion</h3> This study adds compelling empirical evidence that T21 decreased purchases of the cigarette brands consumed disproportionately by young people, the policy’s target demographic.
Professional Liability
Authors: Martin J. Hatlie
Journal: JAMA (1989)

In 1987, a story in the<i>New York Times</i>(February 9, 1987;sect A:1) declared that the tort liability crisis of the mid-1980s was over. The reinsurance market was softening, claims frequency was stabilizing across the country, and tort reform had been achieved in Florida, the "Beirut of Medicine." One year later, a report issued by New York State's superintendent of insurance revealed that medical liability premiums in that state, frozen for years at artificially low rates, were endangering the solvency of its liability insurers and recommended immediate premium increases of up to 80%.<sup>1</sup>Florida's ceiling on noneconomic damages had been overturned in the courts, and insurers were nonrenewing more than 5000 physicians in the state while emergency department physicians were "on strike" (Associated Press, July 2, 1987). In the absence of a focused understanding of the many weaknesses of the tort compensation and quality assurance systems in its home
Abstract 5314: Smad4 loss upregulates chemokine expression and promotes tumor inflammation and growth in head and neck cancer
Authors: Jude Masannat, Xuefeng Wang, Biwei Cao, FeiFei Song, Ritu Chaudhary, Janis de la Iglasia, Ciaara Gorgoglione, Robbert Slebos, Christine Chung
Journal: Cancer Research (2019)

Abstract Background: Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer worldwide. Of the patients diagnosed with HNSCC, previous findings show that SMAD4 loss is more common in recurrent HNSCC patients compared with newly diagnosed cases and is strongly associated with poor patient survival and metastases. SMAD4 is a tumor suppressor gene and is a central mediator of the transforming growth factor β (TGF-β) signaling pathway and acts as a co-SMAD which binds receptor-regulated SMADs such as SMAD2 and 3. SMAD2/3/4 complex is important for regulating downstream gene transcription that is involved in tumor invasion and metastasis. Purpose: Since the TGF-β pathway is highly dysregulated in HNSCC, we investigate in this study how SMAD4 downregulation alters TGF-β pathway signaling and the tumor microenvironment. Results: Using isogenic HNSCC cell lines, we visualized using immunofluorescence staining that levels of activated phospho-SMAD2 in the nucleus are correlated with expression of SMAD4. Genome-wide screening using Gene Set Enrichment Analysis (GSEA) further revealed changes in gene expression during SMAD4 knockdown in HNSCC cells. From GSEA results, the 20 most significantly altered Gene Ontology (GO) pathways were determined. It was shown that majority of these GO pathways are associated with regulating neutrophil migration and chemotaxis with an upregulation of CXC chemokine gene expression, specifically with CXCL1. In contrast, anti-tumor chemokines, such as CXCL9 and CXCL11, were downregulated during loss of SMAD4 expression. Using an orthotopic mouse model we show that in vivo, decreased expression of SMAD4 promotes tumor take and growth. Conclusion: Collectively, these results suggest that HNSCC tumors with SMAD4 loss may have poor prognosis attributed to immunosuppressive functions of chemokine expression that acts on tumor-associated neutrophils. Citation Format: Jude Masannat, Xuefeng Wang, Biwei Cao, FeiFei Song, Ritu Chaudhary, Janis de la Iglasia, Ciaara Gorgoglione, Robbert Slebos, Christine Chung. Smad4 loss upregulates chemokine expression and promotes tumor inflammation and growth in head and neck cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 5314.
Optimal Prediction of Diabetes
Authors: Michael P. Stern
Journal: Annals of Internal Medicine (2002)

Letters19 November 2002Optimal Prediction of DiabetesMichael P. Stern, MD, Ken Williams, MS, and Steven M. Haffner, MDMichael P. Stern, MDUniversity of Texas Health Science Center; San Antonio, TX 78229 (Stern, Williams, Haffner)Search for more papers by this author, Ken Williams, MSUniversity of Texas Health Science Center; San Antonio, TX 78229 (Stern, Williams, Haffner)Search for more papers by this author, and Steven M. Haffner, MDUniversity of Texas Health Science Center; San Antonio, TX 78229 (Stern, Williams, Haffner)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-10-200211190-00020 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:The Web site www.statcoder.com contains a large collection of physician-support software that can readily be “hot synched” into a personal digital assistant. This Web site was brought to our attention by one of our younger colleagues, who told us that she and others use these programs frequently for patient evaluation and counseling. Among the software programs available on this Web site is the National Cholesterol Education Program Adult Treatment Guidelines III, which includes the Framingham risk equation, an equation analogous to the one presented in our paper. Also available is an equation for estimating preoperative risk. There is ...Reference1. Stern MP, Fatehi P, Williams K, Haffner SM. Predicting future cardiovascular disease: do we need the oral glucose tolerance test? Diabetes Care. 2002;25:1851-6. [PMID: 12351490] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Michael P. Stern, MD; Ken Williams, MS; Steven M. Haffner, MDAffiliations: University of Texas Health Science Center; San Antonio, TX 78229 (Stern, Williams, Haffner) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoIdentification of Persons at High Risk for Type 2 Diabetes Mellitus: Do We Need the Oral Glucose Tolerance Test? Michael P. Stern , Ken Williams , and Steven M. Haffner Optimal Prediction of Diabetes Greg Bombassei Metrics Cited byThe metabolic syndrome: setting the scene. The cons 19 November 2002Volume 137, Issue 10Page: 856KeywordsCholesterolOral glucose tolerance testTreatment guidelines ePublished: 19 November 2002 Issue Published: 19 November 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Illness Associated With Red Tide—Nassau County, Florida, 2007
Journal: JAMA (2008)

A "red tide" is a harmful algal bloom that occurs when toxic, microscopic algae in seawater proliferate to a higher-than-normal concentration (i.e., bloom), often discoloring the water red, brown, green, or yellow. Red tides can kill fish, birds, and marine mammals and cause illness in humans. Florida red tide is caused by the dinoflagellate Karenia brevis, which produces toxins called brevetoxins and is most commonly found in the Gulf of Mexico; however, K. brevis blooms also can occur along the Atlantic coast. On September 25, 2007, a cluster of respiratory illnesses was reported to the Nassau County Health Department (NCHD) in northeastern Florida. All of the ill persons were employed at a beach restoration worksite by a dredging company operating at Fernandina Beach; they reported symptoms of eye or respiratory irritation (e.g., coughing, sneezing, sniffling, and throat irritation). NCHD and the Florida Department of Health promptly conducted epidemiologic and environmental investigations and determined the illnesses likely were associated with exposure to a red tide along the Atlantic coast. These actions highlight the importance of rapid investigation of health concerns with potential environmental causes to enable timely notification of the public and prevent further illness.
Acute Care of Inferior-Wall Myocardial Infarction
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review La Perméabilité et les Obturations Tubaires. (Stérilité Infections Salpingiennes Chirurgie Tubaire) . By Claude Beclere. Préface by Prof. P. Lecène. Paris. Masson et Cie Éditeurs, Libraires de L'Académie de Médecine 120, Boulevard Saint-Germain. 1929. Price 50 Fr.
Journal: New England Journal of Medicine (1930)
Highlights
Journal: JAMA Cardiology (2017)

Outcomes After Everolimus-Eluting Stent Implantation 1303Outcomes data for women and minority patients after percutaneous coronary intervention with everolimus-eluting stents are limited.Batchelor and coauthors assessed 1-year outcomes in patients enrolled in the PLATINUM Diversity study and the PROMUS Element Plus Post-Approval Study, including 1635 white men, 1863 women (white and minority), and 1059 minority patients (women and men).Compared with white men, the adjusted risk of death/ myocardial infarction was higher among women and minority patients, and the adjusted risk of myocardial infarction was higher in minority patients.These differences were driven primarily by nonstent-related myocardial infarctions.Adverse events were also associated with social determinants of health, including widowhood and insurance status.
Enough Is Enough
Authors: Deborah Stepp
Journal: Annals of Internal Medicine (2014)

Letters3 June 2014Enough Is EnoughDeborah Stepp, RNDeborah Stepp, RNFrom Philadelphia, Pennsylvania.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L14-5011-3 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITORI am concerned about how Guallar and colleagues' editorial (1) was presented. I believe that a large set of persons should take vitamins: pregnant women. As a matter of fact, any woman of childbearing age should take vitamins because we do not always know whether we will become pregnant, even if we use protection (2).Guallar and colleagues did not address this problem. I am worried that even one woman of reproductive age may stop taking a multivitamin to the detriment of a fetus that she may be carrying.Deborah Stepp, RNPhiladelphia, PennsylvaniaReferences1. Guallar E, Stranges S, Mulrow C, Appel LJ, Miller ER. Enough is enough: Stop wasting money on vitamin and mineral supplements [Editorial]. Ann Intern Med. 2013;159:850-1. [PMID: 24490268] LinkGoogle Scholar2. Green NS. Folic acid supplementation and prevention of birth defects. J Nutr. 2002;132:2356S-2360S. [PMID: 12163692] CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: From Philadelphia, Pennsylvania.Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L14-0079. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEnough Is Enough: Stop Wasting Money on Vitamin and Mineral Supplements Eliseo Guallar , Saverio Stranges , Cynthia Mulrow , Lawrence J. Appel , and Edgar R. Miller III Enough Is Enough Balz Frei , Bruce N. Ames , Jeffrey B. Blumberg , and Walter C. Willett Enough Is Enough Irvine Mason Enough Is Enough Thomas R. Friberg Enough Is Enough Jessica Fargnoli , Joyce Greenleaf , and Melissa Hafner Enough Is Enough Eliseo Guallar , Saverio Stranges , Cynthia Mulrow , Lawrence J. Appel , and Edgar R. Miller III Enough Is Enough Irvine Mason Enough Is Enough Jessica Fargnoli , Joyce Greenleaf , and Melissa Hafner Enough Is Enough Thomas R. Friberg Enough Is Enough Eliseo Guallar , Saverio Stranges , Cynthia Mulrow , Lawrence J. Appel , and Edgar R. Miller III Enough Is Enough Balz Frei , Bruce N. Ames , Jeffrey B. Blumberg , and Walter C. Willett Metrics 3 June 2014Volume 160, Issue 11Page: 808KeywordsConflicts of interestDisclosureFetusesPregnancyVitamins ePublished: 3 June 2014 Issue Published: 3 June 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Perceived stress and risk of adult‐onset asthma and other atopic disorders: a longitudinal cohort study
Authors: N. H. Rod, T. S. Kristensen, P. Lange, E. Prescott, F. Diderichsen
Journal: Allergy (2012)

Abstract Background Psychological stress can affect airway inflammatory response to irritants and allergens, but the importance of stress in the etiology of adult‐onset respiratory and dermatologic allergic disorders remains unclear. We aim to address the relationship between perceived stress and the risk of adult‐onset asthma, allergic rhinitis, atopic dermatitis, and asthma/bronchitis medication. Methods Participants ( n = 9785) from the Copenhagen City Heart Study, Denmark, free of atopic disorders at baseline in 1981–1983 were asked questions on stress intensity and frequency. They were followed for first‐time asthma hospitalization in nationwide registers until 2010, with &lt; 0.1% loss to follow‐up. Objective measures of lung function allowed for thorough adjustment for confounding and prevented ambiguity between diagnosis of asthma and chronic obstructive lung disease. Daily intake of asthma/bronchitis medication and incidence of asthma, allergic rhinitis, and atopic dermatitis were assessed by self‐report after 10 years of follow‐up in 5648 persons. Results Perceived stress was associated with atopic disorders in a dose‐dependent manner ( P trend &lt; 0.001). High vs low stress was associated with higher risk of self‐reported asthma incidence ( OR = 2.32; 95% CI : 1.47–3.65), daily intake of asthma/bronchitis medication ( OR = 2.26; 95% CI : 1.42–3.58), first‐time asthma hospitalization ( HR = 2.01; 95% CI : 1.41–2.86), allergic rhinitis ( OR = 1.64; 95% CI : 0.99–2.72), and atopic dermatitis ( OR = 1.75; 95% CI : 1.11–2.77). The associations were similar for smokers and nonsmokers. Conclusions Stress is strongly associated with asthma incidence and hospitalization, use of asthma medication as well as with allergic rhinitis and atopic dermatitis in adults.
ORIGINAL INVESTIGATIONS ON THE NATURAL HISTORY, (SYMPTOMS AND PATHOLOGY) OF YELLOW FEVER. 1854-1894.
Authors: JOSEPH JONES
Journal: JAMA (1895)

<h3>Chapter III.</h3><h3>Case 7.</h3> —Yellow fever; severe case; jaundice; albumen in urine; recovery. Wm. Busse; age 25; native of Germany. Has been in New Orleans seven months,and came here from Red River. Seized with pain in the head and back and fever on Oct. 11, 1873, and entered Charity Hospital, Ward 24, October 13. At time of admission, complained of pain in head, back and knees. Tongue red at tip and edges and coated in the center. October 14, conjunctiva of eyes congested and yellow; surface of body yellow; nausea and vomiting; breath and odor of body foul; urine abundant and contains albumen and casts. On October 15 and 16, pulse intermittent, but the patient improving. On October 20, the patient was able to sit up and to be brought down to my clinical lecture in the amphitheater, and on October 22 was able to walk about the hospital. After
Reproductive toxicology. Diethylene glycol monoethyl ether.
Authors: James Lamb, Jerry Reel, A Lawton
Journal: Environmental Health Perspectives (1997)

NTIS #PB85137123Diethylene glycol monoethyl ether (DGEE), a chemical and solvent used in industry and in consumer goods, was tested for reproductive toxicity in Swiss CD-1 mice using the RACB protocol (Williams et al., Fundam Appl Toxicol 14:622-635 [1990]).It was part of a large structure-activity series of glycol ethers and congeners evaluated using this design, generating data on compounds for which there were few or no reproductive data in the open literature.Based on a pilot dose-set- ting study using food and water consump- tion, as well as body weight, viability, and clinical signs, doses for the main study were set at 0.0, 0.25, 1.25, and 2.5% DGEE in drinking water for approximately 21 weeks.Based on water consumption
THE IMPROVEMENT OF THE MEDICAL AND SCIENTIFIC WORK IN OUR HOSPITALS FOR THE INSANE.
Journal: JAMA (1903)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The specialty of preventive medicine. A review of two decades
Authors: H. V. Ellingson
Journal: JAMA (1969)

This year of 1968 represents the 20th anniversary of the founding of the American Board of Preventive Medicine. In these two decades the whole world has been swept by changes—social, scientific, and educational—and many of these changes have had special significance for us in preventive medicine. Certainly this has been an exciting period for the board. As we move into our 21st year, the anniversary provides an occasion to review some of the causes for satisfaction regarding the specialty of preventive medicine, as well as some causes for concern. My emphasis will be on matters which have a bearing on the status of the specialty, and on education and training—the preparation of future leaders in our field. <h3>Causes for Satisfaction</h3> First, it seems to me that in the past 20 years preventive medicine has come to the end of one era and entered a wholly new one. We seem to
Incorrect Name in Citation in: Guideline Promotes Early, Aggressive Sepsis Treatment to Boost Survival
Authors: Angela Sauaia, Joshua Miller, Ernest Moore, David Partrick
Journal: JAMA (2013)

ten required intensive care, and claimed more lives, justifying focusing on pediatric firearm injuries as a prevention priority.Study limitations include trauma registry deficiencies (such as inconsistent capturing of intentionality and exclusion of deaths at scene, which is a significant fraction of firearmrelated deaths); and data restricted to 2 trauma centers, which may not generalize to other regions.In addition, data were available only until 2008; however, there has been no substantial decline in published firearm death rates in Colorado since 2008 (2.2 per 100 000 persons aged 4-17 years in 2000, 1.9 in 2009, and 2.8 in 2011).