tbuckley/cabot-search huggingface dataset:
Carbon Monoxide Poisoning Associated With Use of LPG-Powered (Propane) Forklifts in Industrial Settings--Iowa, 1998
Journal: JAMA (2000)

In 1998, the Iowa Department of Public Health (IDPH) and Iowa State University (ISU) Extension Department, with the assistance of local health departments, investigated a series of carbon monoxide (CO) poisonings associated with the use of liquified petroleum gas (LPG)-powered forklifts in light industry. In each episode, forklifts emitting high CO concentration levels were operated in inadequately ventilated warehouse and production facilities, which resulted in high CO accumulations. Employees at each site developed symptoms of CO poisoning, and some employees received inadequate or inappropriate medical care. This report summarizes the investigations and provides recommendations to prevent such incidents.
The hiatus hernia slides back into prominence
Authors: J DENT
Journal: Gut (1999)

<h3>Abstract</h3> <h3>Background</h3> Physical activity and sedentary behavior has inconsistent effects on fertility. High body mass index is associated with infertility but to our knowledge, very few studies have explored body composition in association to fertility. <h3>Objective</h3> To assess the association between physical inactivity, sedentary behavior, body composition and idiopathic infertility in French men and women. <h3>Design</h3> We conducted a case-control multicentric observational study. 159 infertile (79 men and 80 women) and 143 fertile (72 men and 71 women) were recorded in four fertility centers. <h3>Main Outcome Measures</h3> Participants completed self-administered questionnaires on sociodemographic and lifestyle characteristics, dietary intake, physical activity and sedentary behavior. Anthropometrics were measured, and bioelectrical impedance analysis was used to estimate body composition. Multivariable logistic regression was used to analyze the association of fertility with PA level and sedentary behavior. <h3>Results</h3> In men, being physically inactive (Odd ratio [OR] 2.20; 95% confidence interval [CI], 1.06, 4.58) and having fat mass greater than the reference values for their age (OR 2.83; 95%CI, 1.31, 6.10) were positively associated with infertility. Sedentary behavior and fat-free mass were not related to infertility in men. In women, sedentary behavior (OR 3.61; 95%CI, 1.58, 8.24), high body fat (OR 3.16; 95%CI, 1.36, 7.37) and low fat-free mass (OR 2.65; 95%CI, 1.10, 6.37) were associated with infertility. PA level was not associated with fertility in women. <h3>Conclusions</h3> This study suggests that sedentary behavior and physical inactivity would represent two independent risk factors associated with fertility. The various elements that make up physical activity (frequency, intensity, time, and type of exercise) and the interrupting time spent sitting should be considered. Body composition variation should be explored further in relation to the biological pathways involved in idiopathic infertility. Moreover, the improvement of lifestyle factors should be considered in infertility treatment.
Preliminary Medical Examiner Reports of Mortality Associated With Hurricane Charley—Florida, 2004
Journal: JAMA (2004)

On August 13, 2004, at approximately 3:45 p.m. EDT, Hurricane Charley made landfall at Cayo Costa, a Gulf of Mexico barrier island west of Cape Coral, Florida, as a Category 4 storm, with sustained winds estimated at 145 mph. Charley was the strongest hurricane to make landfall in the United States since Hurricane Andrew in August 1992. Charley created a 7-foot storm surge in Fort Myers, then traversed the state in 9 hours, continuing in a northeast direction across eight counties. This report presents preliminary data from Florida medical examiners (MEs), which indicated that 31 deaths were associated with Hurricane Charley. Deaths might be reduced through coordinated hurricane planning, focused evacuations, and advance communication to the public regarding the environmental hazards after a natural disaster.
Nervous States, Their Nature and Causes.
Journal: JAMA (1910)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment of Morgagni-Adams-Stokes Disease with Internal Electric Stimulation
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Author Name Omitted.
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MEDICAL LICENSURE STATISTICS FOR 1940
Journal: JAMA (1941)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
TYROSINASE, A FERMENT PRODUCING A PIGMENT RESEMBLING MELANIN.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
32P Heterogeneity analysis of DW MRI as a biomarker for prediction of overall survival and 6 month PFS in GBM patients
Authors: M. Beigi, A. Fathi Kazerooni, M. Safari, A. Ameri, B. Moini, M. Shojaee Moghdam, H. Salighehrad
Journal: Annals of Oncology (2016)
In the matter of witch hunts
Authors: J. E. Osborn
Journal: JAMA (1978)

REMEMBER the days of the early 1950s? Accusations, congressional investigations, and imputed guilt could all be coalesced by the simple tactic of repetitious statements of purported wrongdoing. Professionals of extraordinary quality were brought down, and some say that whole agencies of the government never recovered from the loss of invaluable talent that resulted. That era was not the first in which such tactics had proved effective and, sadly, it was not the last. I think we are currently observing a kind of biomedical McCarthyism, which, if unchecked, can leave a gaping hole where strong, scientifically based regulation of biologics used to be. The Bureau of Biologics of the Food and Drug Administration is an excellent agency of government that is under siege from a small cadre of strident critics. There is room for grave concern that their sustained attack might soon exceed the patience of the talented group of scientists
Clinical Inertia
Authors: Daniel Reinharth
Journal: Annals of Internal Medicine (2002)

Letters17 September 2002Clinical InertiaDaniel Reinharth, MDDaniel Reinharth, MDEast Meadow, NY 11554-2201Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-137-6-200209170-00026 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:In the excellent article on clinical inertia by Phillips and colleagues (1), there is a section titled "Use of 'Soft' Reasons To Avoid Intensification of Therapy." I believe that the impact of such soft reasons cannot be overemphasized. As a practicing clinician, I can testify to the difficulty in getting patients to take medications for apparently asymptomatic conditions, as well as having patients continue to take such medications over the long haul. If long-term adherence to treatment is enhanced by obtaining patient "buy-in," then strategies employing nonmedication trials may delay reaching goal levels in the short run ...Reference1. Phillips LS, Branch WT, Cook CB, Doyle JP, El-Kebbi IM, Gallina DL, et al . Clinical inertia. Ann Intern Med. 2001;135:825-34. [PMID: 11694107] LinkGoogle Scholar Author, Article, and Disclosure InformationAuthors: Daniel Reinharth, MDAffiliations: East Meadow, NY 11554-2201 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoClinical Inertia Lawrence S. Phillips , William T. Branch Jr. , Curtiss B. Cook , Joyce P. Doyle , Imad M. El-Kebbi , Daniel L. Gallina , Christopher D. Miller , David C. Ziemer , and Catherine S. Barnes Clinical Inertia Lawrence S. Phillips , Joyce P. Doyle , and William T. Branch Jr. Clinical Inertia Michael Steinberg Clinical Inertia James L. Wofford Metrics Cited byKnowledge assessment regarding secondary prevention of coronary heart disease- a multi centre surveyA diabetes education multimedia program in the waiting room setting 17 September 2002Volume 137, Issue 6Page: 547-548KeywordsAdverse reactionsDrugsPatientsStatinsTreatment guidelines ePublished: 17 September 2002 Issue Published: 17 September 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Subclinical Hypothyroidism
Authors: David S. Cooper
Journal: JAMA (1987)

Hypothyroidism was believed to be a rare and potentially fatal clinical entity when it was first described more than a century ago.<sup>1</sup>With the subsequent development of techniques to measure thyroid hormone levels in serum, hypothyroidism was shown to be a common disorder, with a broad spectrum of severity. But it was not until the early 1970s, when thyrotropin (thyroid-stimulating hormone [TSH]) measurements became routine, that we learned just how common the disorder and how broad the spectrum.<sup>2,3</sup> We now know that the mildest form of hypothyroidism, manifested solely by an elevated serum TSH concentration, is present in approximately 5% of the population, with a prevalence in women older than age 60 years that approaches 15%.<sup>4,5</sup>Of 28.5 million people older than age 65 years in America, 17 million of whom are women, an estimated 3.5 million have mild thyroid impairment, appropriately termed<i>subclinical hypothyroidism</i>. Autoimmune thyroid
EDITORIAL
Journal: British Journal of Sports Medicine (1971)

We offer our sincere apologies for the long delay in distributing the last number of the Journal, Vol.V no.3.The manuscript was almost completed late in October 1970, and finished under adverse climatic conditions during the early part of the Electricity Workers' dispute at the beginning of November.At the printers the electric typewriters, printing presses and all photographic equipment was by this time out of action, and the premises too dark and too cold for work to be done.By the time the dispute ended, a large back-log of work had accummulated, B.A.S.M. jobs being only some of many other contracts, all overdue.Eventually the Journal was produced, thanks to the hard and willing work of many of the employees in Wells & Blackwell
Predictions
Authors: Michelle M. Kittleson
Journal: JAMA Cardiology (2019)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Cardiology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Cardiology journal
Abstract 142: IL-10 Regulates Inflammation to Improve LV Physiology After Myocardial Infarction by Stimulating M2 Macrophage Polarization and Fibroblast Activation
Authors: Mira Jung, Yonggang Ma, Rugmani Padmanabhan Iyer, Andriy Yabluchiansky, Michael R Garrett, Merry L Lindsey
Journal: Circulation Research (2017)

Inflammation resolution is important for scar formation following myocardial infarction (MI) and requires the coordinated actions of macrophages and fibroblasts. In this study, we hypothesized that exogenous interleukin-10 (IL-10), an anti-inflammatory cytokine, promotes post-MI repair through actions on these cardiac cell types. To test this hypothesis, C57BL/6J mice (male, 3-6 months old, n=24/group) were treated with saline or IL-10 (50 μg/kg/day) by osmotic mini-pump infusion starting at day 1 post-MI and sacrificed at day 7 post-MI. IL-10 infusion doubled plasma IL-10 concentrations by day 7 post-MI. Despite similar infarct areas and mortality rates, IL-10 treatment significantly decreased LV dilation (1.6-fold for end-systolic volume and 1.4-fold for end-diastolic volume) and improved ejection fraction 1.8-fold (both p&lt;0.05). IL-10 treatment attenuated inflammation at day 7 post-MI, evidenced by decreased numbers of Mac-3+ macrophages in the infarct (p&lt;0.05). LV macrophages isolated from day 7 post-MI mice treated with IL-10 showed significantly elevated gene expression of M2 markers (Arg1, Ym1 and TGF-β1; all p&lt;0.05). We further performed RNA-seq analysis on post-MI cardiac macrophages and identified 410 significantly different genes (155 increased, 225 decreased by IL-10 treatment). By functional network analysis grouping, the majority of genes (133 out of 410) were part of the cellular assembly and repair functional group. Of these, Hyaluronidase 3 (Hyal 3) showed the largest fold change between groups. IL-10 treatment decreased Hyal3 by 28%, which reduced hyaluronan degradation and limited collagen deposition (all p&lt;0.05). In addition, ex vivo IL-10 treatment increased fibroblast activation (proliferation, migration, and collagen production), an effect that was both directly and indirectly influenced by macrophage M2 polarization. Combined, our results indicate that in vivo infusion of IL-10 post-MI improves the LV microenvironment to dampen inflammation and facilitate cardiac wound healing.
Predicting Prognosis After Myocardial Infarction
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
INTOXICATION OF PHYSICIAN MAY BE SHOWN.
Journal: JAMA (1894)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
British Association for the Study of the Liver
Authors: C Healey, J Christie, E Ai, V Cerun- Dolo, R Chapman, M Rosenberg, C Healey, S Mcadam, M Plebanski, M Bahr, J Iredale, M Clark, M Arthur, A Mann
Journal: Gut (1996)

A vigorous peripheral blood cytotoxic T-cell (CTL) response is associated with viral clearance in acute HBV infection but intrahepatic CTL may mediate hepatocyte dam- age in chronically infected subjects.Escape from immune detection is thought to lead to persistent infection.In a family chronically infected with HBV with differing outcomes we have studied the effect of mutation within a core HLA-Al restricted CTL epitope on HLA-Al binding and disease course.HBV core protein was sequenced in viral isolates from HLA-typed family members.Synthetic peptides based on the HBV sequences were tested for binding to HLA-Al molecules in vitro using an HLA class I assembly assay.Binding was correlated with disease course.One patient with a mutation in the A1 epitope, which abrogates HLA-Al binding and three who lack HLA-Al had no liver disease.Two patients with mutations that increased binding and one patient without mutations developed chronic liver disease.A benign course of HBV infection may result from failure of CTL recognition due to mutations in HLA binding residues that abro- gate binding.