tbuckley/cabot-search huggingface dataset:
Oximetry
Authors: Ellen McCulloch Lovell
Journal: JAMA (2019)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The new NHS: restricting GPs' access to x ray services
Authors: T S Brown
Journal: BMJ (1991)

breast screening we have found a difference in the ability to trace Asian and non-Asian women.In a study in central Manchester we were unable to gain access at their address for only six of 93 Asian non- attenders compared with 26% of 103 non-Asian women.Bv gaining some information from other occupiers we established that half of the Asian women were no longer resident at the address on the invitation.Though this was the main reason for non-attendance among Asian women, it could only be estimated to be the reason for 26-54% of the non-Asian women.Our impression was of two different types of response: when we followed up non-Asian women access was more difficult and it was harder to gather information from other occupiers or neigh- bours, whereas more of the Asian community were available and were more helpful.Furthermore, the outcome of personal visits to non-attenders was more successful among Asian women: of the Asian women contacted and offered additional appointments, 70% subsequently attended for screening whereas only 36% of non-Asian women did so.In terms of the effectiveness of personal visits on the overall uptake of screening attendance for breast screening by Asian women increased by 9%.
Poster Session TPS 19-33
Journal: Allergy (2016)

Background: Hypersensitivity reaction to iron salts have not been occured commonly.Immediate and late immunologic reactions or non-immunologic reactions by mast cell activation could be seen.There were limited number of case reports about desensitization with iron salts in literature.Our aima is to report a case who experienced anaphylactic reaction by using iron salts 2 and 3 were succesfully and rapidly desensitized to ferous glisin sulphate.Method: Oral provocation test with ferrous II glisin sulphate was performed to the patient.When she had pruritus, erythema and dispnea on the third dose (50 mg elemantal iron), she was treated immediately.Rapid desensitization protocol was started at tenth day after the oral provocation test.Results: The patient had severe anemia at the beginning (plasma Hb:7.7 g/dl, hematocrite value:24.1%,MCV:72 fl).After the premedication with Pheniramin maleat and prednisolone, the desensitization was started.The protocol was modified from the 2 days protocol of Demir and coll.Solution form of ferrous glisin sulphate was used in the protocol.First dose of desensitization was 1:10 000 dilution of daily dose of ferrous II glisin sulphate.Single day protocol was performed at 13 steps.Three seperate bottle were prepared and one of them contained the originale dose.Desensitization was started with 0.25 ml (0.01 mg elemantal iron) from the second bottle containing 1:100 dilution of the originale dose and dose was doubled in every 20 min.The patient was desensitized successfully at the end of the first day.At the second day the treatment have been continued with the original dose.There have been no problem on the second month of desensitization.Conclusion: Single day rapid desensitization with iron salts has never been mentioned in literature.As being fast and helpful, this protocol would be useful in the patients who have hypersensitivity to iron salts and having no other alternative treatment.
Thyroid hypofunction after exposure to fallout from a hydrogen bomb explosion
Authors: P. R. Larsen
Journal: JAMA (1982)

Thyroid function was evaluated in the Marshallese who were accidentally exposed to fallout-containing radioiodine isotopes in 1954. Measurements of thyrotrophin (TSH, thyroid-stimulating hormone) levels and free thyroxine (T4) index (FT4I) have revealed that, among 86 persons exposed on Rongelap and Ailingnae atolls, 14 have shown evidence of thyroid hypofunction. This was first noted in some individuals about ten years after exposure. Only two of these showed clinical evidence of hypothyroidism. The most marked TSH elevations were noted in nine persons exposed when younger than 6 years, with estimated doses to the thyroid from 390 to 2,100 rad. Most of this group subsequently had surgery for removal of thyroid nodules. The remaining five cases have been noted more recently among 36 surviving adults exposed at an older age who showed no other detectable thyroid abnormalities. This group had received estimated thyroid doses ranging from 135 to 335 rad and showed modest elevation of serum TSH levels (6 to 9 μU/mL) and a slightly subnormal FT<sub>4</sub>I. No abnormalities were found in persons on Utirik who received substantially less radiation, and hypothyroidism was present in less than 1% of the control, unexposed Marshallese. The high prevalence of a thyroid hypofunction in these persons indicates that this condition, as well as thyroid nodularity, can be a delayed complication of exposure to early fallout from a nuclear explosion. The fact that a significant fraction of the radiation to the thyroid was from short-lived radioiodine isotopes (<sup>132</sup>I,<sup>133</sup>I,<sup>135</sup>I), as opposed to<sup>131</sup>I, may account for the severity of the thyroid damage. (<i>JAMA</i>1982;247:1571-1575)
Fibrinolysis During Open Heart Surgery
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Five-year findings of the hypertension detection and follow-up program. I. Reduction in mortality of persons with high blood pressure, including mild hypertension. Hypertension Detection and Follow-up Program Cooperative Group
Journal: JAMA (1979)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
British Policy on Therapeutic Abortion
Journal: JAMA (1967)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tissue Kallikreins And Kinins: Regulation And Roles In Hypertensive And Diabetic Diseases
Authors: H. Margolius
Journal: The Annual Review of Pharmacology and Toxicology (1989)

Due to the massive data sets available for drug candidates, modern drug discovery has advanced to the big data era. Central to this shift is the development of artificial intelligence approaches to implementing innovative modeling based on the dynamic, ...Read More
Surgical Emergencies in Practice.
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
'LFTs' test more than the liver
Authors: J. H. Helzberg
Journal: JAMA (1986)

Biochemical studies of the liver, known to clinicians as "LFTs," can be sensitive to a greater or lesser degree, but they are never specific. The clinician can use them for no more than to infer what is going on in the liver. That is especially true of metastatic liver disease, where it has long been known that, even with diffuse hepatic metastases and after combining laboratory tests with imaging procedures, no more than 75% of metastases can be detected.<sup>1</sup> In this issue ofTHE JOURNAL, Larroquette and coworkers<sup>2</sup>reenforce the view that abnormal findings from hepatic chemistries in patients receiving combination chemotherapy for breast cancer do not necessarily, or usually, signify metastatic disease to the liver. Fifty-nine percent of 190 patients in their retrospective study had abnormal findings from liver chemistries while receiving chemotherapy. Within one year after treatment, however, 90% of those who had developed hepatic enzyme
Septic arthritis in children
Authors: A. Howard, M. Wilson
Journal: BMJ (2010)

As many studies around the theme of ‘too much medicine’ attest, investigations are being ordered with increasing frequency; similarly the threshold for providing treatment has lowered. Our contention is that trust (or lack of it) is a significant factor in influencing this, and that understanding the relationship between trust and investigations and treatments will help clinicians and policymakers ensure ethical decisions are more consistently made. Drawing on the philosophical literature, we investigate the nature of trust in the patient–doctor relationship, arguing that at its core it involves a transfer of discretion. We show that there is substantial empirical support for the idea that more trust will reduce the problem of too much medicine. We then investigate ways in which trust can be built, concentrating on issues of questioning, of acknowledging uncertainty and of shouldering responsibility for it. We argue that offering investigations or treatments as a way of generating trust may itself be an untrustworthy way of proceeding, and that healthcare systems should provide the institutional support for facilitating continuity, questioning and the entrusting of uncertainty.
Phase II Trial Of L-Asparaginase Plus Concurrent Chemoradiotherapy Followed By Midle (methotrexate, ifosfamide, etoposide, dexamethasone, and L-asparaginase) Chemotherapy For Patients With Newly Diagnosed Stage I/II Extranodal NK/T-Cell Lymphoma, Nasal Type
Authors: Seok Jin Kim, Dok Hyun Yoon, Seong Hyun Jeong, Dong-Yeop Shin, Sung Hwa Bae, Junshik Hong, Eun Kyung Park, Se Hyung Kim, Ho-Young Yhim, Deok-Hwan Yang, Hye Won Lee, Je-Jung Lee, Mark Lee, Hyeon Seok Eom, Jae-Yong Kwak, Jae Hoon Lee, Dae Sik Hong, Cheolwon Suh, Won Seog Kim
Journal: Blood (2013)
Human T-lymphotropic retrovirus type III/lymphadenopathy-associated virus antibody. Association with hemophiliacs' immune status and blood component usage
Authors: J. Jason
Journal: JAMA (1985)

We studied the human T-lymphotropic retrovirus type III /lymphadenopathy-associated virus (HTLV-III/LAV) antibody status of 234 factor VIII concentrate recipients, 36 factor IX concentrate recipients, 69 long-term recipients of frozen packed red blood cells, and 47 persons not receiving routine transfusion therapy. Factor VIII concentrate recipients had a significantly higher rate of seropositivity (74%) than any other group. Factor IX concentrate recipients had a significantly higher rate (39%) than recipients of frozen packed red blood cells (4%) or nontransfused persons (4%). In factor VIII concentrate recipients, HTLV-III/LAV seropositivity was significantly associated with more severe hemophilia, greater factor dosage, elevated immunoglobulin and immune complex levels, lower T-helper lymphocyte numbers, and lower ratios of T-helper to T-suppressor lymphocytes. For factor IX concentrate recipients, seropositivity was associated with more severe hemophilia. Antibody-positive factor IX concentrate recipients had a lower rate of seropositivity to HTLV-III/LAV p41 membrane antigen than did antibody-positive factor VIII concentrate recipients, but factor VIII and factor IX concentrate recipients had similar rates of seropositivity to core antigens. We conclude that both factor VIII and factor IX concentrates may transmit HTLV-III/LAV. For factor VIII recipients, HTLV-III/LAV seropositivity is associated with altered immune test results. (<i>JAMA</i>1985;253:3409-3415)
Paediatric Haematology
Authors: Ruth A. Seeler
Journal: JAMA (1978)

A new book has crossed the ocean to take its place with the general pediatric hematology texts. By American standards, it is extraordinarily concise—only 411 pages. With the exception of one chapter devoted to leukemia and related disorders (ie, oncology), the text is limited to hematology. The clinical descriptions of the hematologic disorders are excellent, and single authorship eliminates the redundancy found in some multiauthored texts. There is good correlation with the basic pathophysiology and developmental aspects of pediatric hematology. The judicious use of line drawings, charts, and tables augments the text and provides sound organizational framework. The black-and-white photomicrographs are of good quality and interspersed appropriately with the textual discussions. Most of the abbreviations are those that are well accepted, so the reader picking up a particular section does not have to go back to the beginning to understand a particular subsection. The text is divided into 20 chapters
Reply
Authors: Giada Sebastiani, Alfredo Alberti
Journal: Hepatology (2009)

We read with interest the detailed comments made by Boursier and Cales1 on our article2 describing a large-scale, multicenter study of sequential algorithms combining noninvasive markers for liver fibrosis. Some comments are necessary. To date, our study represents the largest independent, international study about serum noninvasive markers for liver fibrosis. This study was intended to both validate and optimize our previously described stepwise algorithms for liver fibrosis.3 Boursier and Cales mention the positive predictive value of sequential algorithm for fibrosis evaluation (SAFE) biopsy. We have to underline that SAFE biopsy algorithms have been modeled to answer specific clinical issues. Indeed, the algorithms have been designed to reach a very high negative predictive value for both significant fibrosis and cirrhosis (ranging from 99% to 100%), so that no patient with an indication for antiviral therapy or a specific follow-up can be underdiagnosed. Boursier and Cales refer to a synchronous algorithm combining Fibrometer and FibroTest. It must be emphasized that both FibroTest and Fibrometer are patented tests, with an average cost of 100 euros per test. SAFE biopsy algorithms are based on the aspartate aminotransferase-to-platelet ratio index, which has virtually no cost and global availability, and on FibroTest, which is used as a second-line test only in a subgroup of patients. Indeed, SAFE biopsy algorithms are practical and cost-effective, and the sequential combination approach has been applied by others with excellent performance.4 Another important issue is that SAFE biopsy algorithms adopt widely available and validated tests.5, 6 Although Fibrometer has shown good performance in studies coming from the patenting group, it has been poorly evaluated externally. Moreover, Fibrometer is not widely available in all clinical settings and is not licensed in as many countries as FibroTest. In conclusion, on the basis of the results of our multicenter, large-scale, independent study, SAFE biopsy seems a useful method in clinical practice for large-scale screening of liver fibrosis in patients with hepatitis C. Giada Sebastiani*, Alfredo Alberti* , * Venetian Institute of Molecular Medicine, Padua, Italy, Histology, Microbiology and Medical Biotechnologies, University of Padua, Padua, Italy.
Surgery for Nurses.
Journal: JAMA (1953)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Modelling is useful in evaluating early withdrawal of women from smear test programmes
Journal: BMJ (1999)

Leg symptoms do not correlate with varicose veinsSurgery for varicose veins costs the NHS £400-600m a year yet there is little evidence that it reduces lower limb symptoms.In the Edinburgh vein study (p 353) men and women aged 18-64 completed a questionnaire on the presence of lower limb symptoms and were examined to determine the presence and extent of trunk varices.Women were significantly more likely than men to report heaviness or tension, swelling, aching, restless legs, cramps, and itching.The level of agreement between the presence of symptoms and trunk varices was low, especially in men.These results suggest that, even in the presence of trunk varices, most leg symptoms have a non-venous cause and that surgery is unlikely to ameliorate them.
CHANGE OF ADDRESS
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal