tbuckley/cabot-search huggingface dataset:
Continuing Education Opportunities for Physicians
Journal: JAMA (1986)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A chromosomal region 7p11.2 transcript map: Its development and application to the study of EGFR amplicons in glioblastoma
Authors: Greg D. Eley, Jill L. Reiter, Ajay Pandita, Soyeon Park, Robert B. Jenkins, Nita J. Maihle, C. David James
Journal: Neuro-Oncology (2002)

Cumulative information available about the organization of ampli ed chromosomal regions in human tumors suggests that the ampli cation repeat units, or amplicons, can be of a simple or complex nature.For the former, ampli ed regions generally retain their native chromosomal con guration and involve a single ampli cation target sequence.For complex amplicons, ampli ed DNAs usually undergo substantial reorganization relative to the normal chromosomal regions from which they evolve, and the regions subject to ampli cation may contain multiple target sequences.Previous efforts to characterize the 7p11.2epidermal growth factor receptor (EGFR) amplicon in glioblastoma have relied primarily on the use of markers positioned by linkage analysis and/or radiation hybrid mapping, both of which are known to have the potential for being inaccurate when attempting to order loci over relatively short (< 1 Mb) chromosomal regions.Due to the limited resolution of genetic maps that have been established through the use of these approaches, we have constructed a 2-Mb bacterial and P1-derived articial chromosome (BAC-PAC) contig for the EGFR region A chromosomal region 7p11.
Erratum
Authors: H Armstrong, Mr Aniderson, F Alleni, J Appleyard, Mr Allen, J Altlhaus, Mr Adams, Mr Blake, A Bampton, H Ballance, Mr Bracey, London Beevor, Mr Barling, P Boulton, J Brierley, H Boddy, H Cooper, J Cogllill, Messrs Thos, Co Christy, C Cooke, L Calthrop, Mr Clarke, London Clemiiow, Mr Critic, London Constance, A Clhalmers, D Glasgow, A Davies, ; Douglas, Lon- Don Dunn, L Drage, W Mcadam Eccles, Lon- Don Enquirer, E Ennials, W Fraser, Mr Farrant, E France, Tynie- Moutlh Fair, Square Messrs, Dallas Forbes, Mr Forrest, Lady Fowler
Journal: BMJ (1896)

LETTETRS, NOTES, ETC
TO FLY OR NOT TO FLY
Journal: JAMA (1961)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Daddy's Little Girl
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A blind spot in preventive medicine
Authors: C. L. Williams
Journal: JAMA (1976)

PEDIATRICIANS have without doubt done exceptionally well in keeping our children healthy as children, but at the same time they have fallen far short of creating healthy adults. The result is a blind spot in preventive medicine, a gray zone in chronic disease prevention that needs elucidation before progress can be made against excessive mortality related to heart disease, cancer, and stroke. Many pediatricians still consider chronic disease prevention in childhood controversial and intend to wait for absolute confirmation and clarification of the complex etiologic web surrounding the pathophysiology of these diseases. Cautiously worded articles have labeled atherosclerosis as a "pediatric disease," but have advocated screening and intervention only among those children at high risk,<sup>1</sup>particularly those whose parents have suffered premature heart attacks (be-, fore 50 years of age) even though the children may be grown up by then. We have at least agreed that prevalence studies are
Furby not guilty as ‘charged’
Authors: Greg Basky
Journal: BMJ (1999)

It seems now that Furby, last Christmas's "must have" stuffed toy with a computer chip inside, which was vilified for interfering with medical equipment, does not affect medical machinery after all.An investigation by Health Canada (the government's health ministry), published recently in the Canadian Medical Association Journal (1999;161:971), revealed that the electric and magnetic fields given off by the ear wiggling, eye blinking, fuzzy creature are about 70 times weaker than those emitted by a digital telephone and are "very unlikely" to affect the performance of medical devices, say the study's authors.The furry furore started last January, when Canadian media outlets jumped on reports that the Royal Hospital for Sick Children in Glasgow, Scotland, had apparently banned the toy from its intensive care unit.
The human genome project and international health
Authors: J. D. Watson
Journal: JAMA (1990)

THE HUMAN genome project is a "public good" in the best sense. The purpose of the project is to construct common resources for the study of human genetics. The first fruits will be the development of several kinds of maps of the human genome, and those of other organisms, to permit rapid isolation of genes for further study about DNA structure and function. The major impact of the genome project on medicine will be a slow but steady conceptual evolution—a change in the way that we think about disease and normal physiology. A century ago, a revolution in medicine was in full stride following the discovery of infectious organisms and the dawn of bacteriology. Over the course of the century, the conceptual base of medicine has broadened from gross anatomy of organs to cellular biology to dissection of biochemical pathways. The next step is to study the most fundamental elements
Update: Acquired Immunodeficiency Syndrome—United States, 1994
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Lung injury in patients following thoracotomy
Authors: R Nelson, Hall Clayton
Journal: Thorax (1995)

secretions were high enough".Ms Webber, who reviewed the paper when it was first submitted, is entitled to question the ACBT technique described in this study.However, the authors should have followed the statement "at a higher lung volume" by "when secretions were in the upper airways".The physiotherapy during the study was su- pervised throughout by the same physio- therapist who is experienced and has a special interest in cystic fibrosis.The authors are therefore confident that the ACBT method used fulfils all of the characteristics of a sat- isfactory technique.The only independent arbiters of the method used are the patient subjects them- selves.One of the authors (RN) has therefore personally interviewed six of the more mature and easily available subjects who are known to carry out treatment of their fibrosis conscientiously.Each was first informed that a leading authority on the use of physiotherapy in cystic fibrosis had questioned the method ofACBT used and the validity ofour findings, and that we needed to investigate whether the ACBT that they had been taught was correct.Each subject was asked the same non- committal question: "During ACBT, what characteristic must be fulfilled before you change from mid to low volume huffing to high volume huffing?"In each case the answer was when secretions are felt in the large upper airways.All have agreed that their names, addresses, and telephone numbers may be supplied to the editor if required.We are therefore confident that patients under the care of the Newcastle Cystic Fib- rosis Clinic are being taught and are per- forming ACBT correctly, and that the method used in the study was that described in the published version.We are equally confident that ACBT was used correctly during the study, and that it provides a true comparison between ACBT and autogenic drainage.
EFFECT OF LOOP DIURETICS ON THE FRACTIONAL EXCRETION OF UREA IN DECOMPENSATED HEART FAILURE
Authors: Zachary Cox, Krishna Sury, Veena Rao, Juan Ivey-Miranda, Matthew Griffin, Devin Mahoney, Nicole Gomez, Lesley Inker, Steven Coca, Jeffery Turner, Francis Perry Wilson, Jeffrey M. Testani
Journal: Journal of the American College of Cardiology (2020)
NATIONAL DEPARTMENT OF PUBLIC HEALTH.
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Incorrect Price
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PERMANENT CURE OF RHEUMATISM THROUGH MISADVENTURE.
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pose d'endoprothèses métalliques auto-expansibles pour les sténoses oesophagiennes malignes – changements dans les résultats cliniques au fil du temps
Journal: Endoscopy (2018)

Les endoprothèses métalliques (PM) auto-expansives sont indiquées dans le traitement palliatif et symptomatique de la dysphagie chez les patients avec un cancer de l’œsophage. Plusieurs PM ont été développés au cours des dernières décennies, mais sans preuve d’une amélioration de leur efficacité.
Abstract P271: Genetically Induced Moderate Inhibition of the Proteasome in Cardiomyocytes Exacerbates Myocardial Ischemia-Reperfusion Injury in Mice
Authors: Zongwen Tian, Hanqiao Zheng, Xuejun (XJ) Wang
Journal: Circulation Research (2011)

Proteasome dysfunction is implicated human ischemic heart disease and observed in experimental myocardial ischemia-reperfusion (I/R) injury. Altered proteasome activities in I/R hearts were reported but it is unclear whether proteasome function in I/R hearts is adequate. Moreover, effects of pharmacological inhibition of the proteasome on I/R injury remain controversial. Hence we sought to determine the adequacy of proteasomal function in I/R hearts and the impact of moderate cardiomyocyte-restricted proteasome inhibition (CR-PSMI) on I/R injury in intact animals. First, myocardial I/R was created by ligation (30min) and subsequent release of the left anterior descending artery in the transgenic (tg) mice overexpressing GFPdgn, a previously validated surrogate proteasome substrate. Compared with the sham controls, myocardial GFPdgn protein levels in the remote area, the board zone, and the a rea a t r isk (AAR) of the ventricle 24hrs after reperfusion were significantly increased, indicative of proteasome functional insufficiency (PFI) in the I/R heart. The most important proteasome peptidase resides in β5 subunits of the 20S proteasome. The clinically used proteasome inhibitor bortezomib targets specially the β5 subunit. To achieve CR-PSMI in intact animals, we engineered and tested a catalytically inactive mouse β5 subunit mutant (T60A-β5) and created multiple tg mouse lines in which T60A-β5 was overexpressed under the control of an attenuated mouse mhc6 promoter. Baseline analyses of the tg lines confirm the ability of T60A-β5 to replace endogenous β5 and inhibit proteasome chymotrypsin-like activities in the heart in a dose-dependent manner. A stable tg line with ∼40% replacement was used in this study. The same I/R procedure caused a significantly greater infarct size in T60A-β5 tg mice (66.2% of AAR) than in the littermate Ntg mice (53.4% of AAR). Under either the sham surgery or the I/R condition, a decrease in phosphorylated AKT and an increase in PKCδ proteins were evident in the tg hearts, compared with the respective Ntg groups. These results show that I/R causes PFI in the heart and PFI plays a pathogenic role in I/R injury. A potential mechanism by which PFI contributes to I/R injury is to suppress AKT activation and exacerbate PKCδ signaling.
Neonatology
Authors: R. James McKay, Jerold F. Lucey
Journal: New England Journal of Medicine (1964)

THE intention of this progress report is to review the published work of the last few years that we believe to be significant or useful to the physician interested in newborn infants and their medical care. The review is not intended to be complete, but concentrates rather on the areas that, in our opinion, are of most immediate or future practical or theoretical interest. Where conflicting opinions exist, we have made a conscientious attempt to point them out, but at the same time, we have not refrained on occasion from expressing our own views or from making tentative prophecies about . . .
Military medical equipment, techniques, often require years of preparation
Authors: P. Gunby
Journal: JAMA (1991)

MILITARY medical planners of the US Air Force, Army, and Navy unofficially share a motto with the Boy Scouts of America:<i>Be Prepared</i>. The point, which has been reemphasized during the Desert Shield/Storm operation, is that it takes time to develop medical equipment and techniques that may be needed in a hurry when a situation such as Iraq's invasion of Kuwait occurs. An example is the temperature-controlled, transportable, standardized (among the services), modular, contingency hospital known as DEPMEDS, or Deployable Medical System, which the services used so effectively for Persian Gulf medical support (<i>JAMA</i>. 1991;265:833). DEPMEDS' history can be traced at least to the late 1970s, when a US Navy rear admiral, Al Wilson, MD, now retired, spearheaded the concept. James A. Zimble, MD, the vice admiral who is surgeon general of the US Navy today, recalls that it took until the mid-1980s to design and bring DEPMEDS into being.
American Bison in a Snow Flurry
Journal: JAMA Internal Medicine (2019)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Internal Medicine HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Internal Medicine journal
Hepatitis C virus genotypes 7, 8, and 9 should be classified as genotype 6 subytpes . Second Department of Medicine Nagoya City University Medical School, Nagoya, Japan; Department of Microbiology1, Kobe University School of Medicine, Kobe, Japan; Department of Virology2, Guangxi Epidemic Prevention Center, PR China; Section of Hepatobiliary Disease3, University of Florida, Gainessville, FL, USA
Journal: Hepatology (1995)
Erratum for the Research Article: “Clinical-grade stem cell–derived retinal pigment epithelium patch rescues retinal degeneration in rodents and pigs” by R. Sharma, V. Khristov, A. Rising, B. S. Jha, R. Dejene, N. Hotaling, Y. Li, J. Stoddard, C. Stankewicz, Q. Wan, C. Zhang, M. M. Campos, K. J. Miyagishima, D. McGaughey, R. Villasmil, M. Mattapallil, B. Stanzel, H. Qian, W. Wong, L. Chase, S. Charles, T. McGill, S. Miller, A. Maminishkis, J. Amaral, K. Bharti
Journal: Science Translational Medicine (2019)