tbuckley/cabot-search huggingface dataset:
Anaesthesia, London
Journal: JAMA (1966)

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INTRAVENOUS INJECTIONS IN RABIES.
Journal: JAMA (1902)

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Intrahepatic Calcification
Authors: H. M. Windsor
Journal: BMJ (1957)

RENAL VENOUS THROMBOSIS MFDITVA'T.lNuRNAL 1343of the vena cava, but not the upper limit.There was no necropsy.A case with great similarity to our own has been reported by Brumfitt and O'Brien (1956).We are indebted to Mr. J. P. Napper for the photographs.
Carotid and Vertebral Artery Disease—A Clinico-Pathological Survey of 70 Cases
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Myeloid cell–specific serine palmitoyltransferase subunit 2 haploinsufficiency reduces murine atherosclerosis
Authors: Mahua Chakraborty, Caixia Lou, Chongmin Huan, Ming-Shang Kuo, Tae-Sik Park, Guoqing Cao, Xian-Cheng Jiang
Journal: Journal of Clinical Investigation (2013)

During the processing of this manuscript, the Western blot in Figure 3D
PDTM-45. INVESTIGATING PEDIATRIC GBM USING IN VIVO SOMATIC MOUSE MOSAICS WITH LOCUS-SPECIFIC, STABLY-INTEGRATED TRANSGENIC ELEMENTS
Authors: Gi Bum Kim, Marina Dutra-Clarke, Rachelle Levy, Hannah Park, Sara Sabet, Jessica Molina, Aslam Akhtar, Serguei Bannykh, Moise Danielpour, Joshua Breunig
Journal: Neuro-Oncology (2017)

Viral vectors and electroporation (EP)-mediated gene transfers are efficient means of inducing somatic mosaicism in mice, but they lack the exquisite control over transgene copy number, gene zygosity, and genomic-locus specificity that genetically engineered mouse models (GEMMs) provide. Here, we develop and demonstrate a simple and generalizable in vivo method, mosaic analysis by dual recombinase-mediated cassette exchange (MADR). MADR allows for stable labeling of mutant cells express transgenic elements from a precisely-defined chromosomal locus. To test our method, we generated reporter-labeled lineages from stem and progenitor cells in a well-defined Rosa26mTmG mouse. We demonstrate the power and versatility of MADR by creating novel glioma models with mixed, reporter-defined zygosity or with “personalized,” H3.3-containing driver mutation signatures from pediatric glioma-each manipulation altering the profile of resulting tumors. Thus, MADR provides a high-throughput genetic platform for the dissection of development and disease, and this rapid method can be applied to the thousands of existing gene-trap mice.
Low K m Aldehyde Dehydrogenase (ALDH2) Polymorphism, Alcohol-Drinking Behavior, and Chromosome Alterations in Peripheral Lymphocytes
Authors: Kanehisa Morimoto, Tatsuya Takeshita
Journal: Environmental Health Perspectives (1996)

Excessive drinking of alcohol is now widely known to be one of the major lifestyle choices that can affect health.Among the various effects of alcohol drinking, cytogenetic and other genotoxic effects are of major concern from the viewpoint of prevention of alcohol-related diseases.Alcohol is first metabolized to acetaldehyde, which directly causes various types of chromosomal DNA lesions and alcohol-related diseases, and is then further detoxified to the much less toxic metabolite acetate.About 50% of Oriental people are deficient in the aldehyde-dehydrogenase 2 isozyme (ALDH2) that can most efficiently detoxify acetaldehyde.We have performed a series of experiments to investigate how the genetic deficiency in ALDH2 affects the behavioral pattern for alcohol drinking and the sensitivity of peripheral lymphocytes to the induction of chromosome alterations by exposure to alcohol and alcohol-related chemicals.We found great effects of the ALDH2 genotypes on alcohol sensitivity and alcohol-drinking behavior.We also show that lymphocytes from habitual drinkers with the deficient ALDH2 enzyme had significantly higher frequencies of sister chromatid exchanges than those from ALDH2-proficient individuals.
From the Centers for Disease Control. Occupational disease surveillance: asthma
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
WEDNESDAY 13TH SEPTEMBER
Journal: Gut (1995)

This ongoing randomised prospective clinical trial has compared the effectiveness of laparoscopic versus open Nissen fundoplication in the control of acid reflux 30 patients (15 each group) underwent fundoplication, between September 1993 and November 1994. 1 patient in the open group was commenced laparoscopically, but converted.The groups were age and sex matched (mean age 47.3 years, range 26-71; 16 male, 19 female).A 22 hour ambulatory oesophageal pH study was performed pre- operatively and again 3 to 4 months post-operatively in all patients.Pre operatively there was no significant difference between the % time pH < 4 (open mean 12.9%, laparoscopic 13.3%; p=0.95), nor number of reflux episodes (pH < 4); (open 55.3, laparoscopic 45.0).Fundoplication significantly reduced both the time pH < 4 (laparoscopic = 0.7%, p= 0.0033; open 1.3%, p= 0.0037) and the number of reflux episodes (lap 4.0; p=0.0011; open 8.2, p=0.0015).There was no significant difference between laparoscopic and open surgery for any acid reflux parameters measured (time pH < 4, p= 0.24; reflux episodes p=0.067).We conclude that laparoscopic fundoplication is equally as effective, and no different to, open surgery, in the control of pathological acid reflux.W2
Perversions of medical technology
Authors: E. Trepman
Journal: JAMA (1990)

<h3>In Reply.—</h3> A few paragraphs are insufficient to list all the historical atrocities that involved chemical, biological, or radioactive agents. Some of the perpetrators have been brought to justice, as in the Nuremberg trials. Others, for example the Japanese scientists believed to have conducted biological warfare experiments on human subjects during the same era as the Third Reich,<sup>1</sup>have never faced charges. And who will ever prosecute the accessories to the crime— Germans who knew but kept silent, Britons and Americans who heard the reports but turned their backs on the victims? Technology of any type can be used for either good or evil. Historical surveys can serve as a warning to physicians about<i>potential</i>abuses of their research. More important, they should challenge us to respond to<i>actual</i>, contemporary abuses, despite the "political pressure that can be brought to bear on medical inquiry."<sup>2</sup> "When allegations of
Ophthalmology
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Mite infestation.
Authors: J Reed, M Hewitt, G I Barrow
Journal: BMJ (1969)

MEDIBRITSHRNg peutic range " in seven of these.One patient (No. -9) developed a deep haematoma of the calf after minor injury and transient haematuria.Further, eight patients were eventually restabilized only on a dose of warfarin lower than might have been expected from the original phenindione dosage.Other centres may be considering chang- ing patients from phenindione to warfarin, and it is suggested that the initial mainten- ance dose of warfarin should be less than that normally calculated and that fairly close monitoring of the prothrombin time might be instituted for the first few weeks after the transfer.-Iam, etc.,
Field Epidemiology
Authors: David H. Mark
Journal: JAMA (1996)

For over 40 years, the Centers for Disease Control and Prevention (CDC) has been training physicians and other health professionals in its Epidemic Intelligence Service training program. The emphasis of this program is on direct hands-on experience with urgent public health problems, rather than classes and coursework. Before such experiences, however, trainees receive brief courses in epidemiology, biostatistics, and public health practice. The chapters of this book are largely derived from the materials used by the CDC to instruct trainees in the methods of epidemiologic field investigations. The content and style of the book strongly reflect this original context of introductory training. The coverage of topics is broad, practical, and informal, rather than rigorous or academic. There are not only the expected chapters, such as those on study design, description, analysis, and interpretation of epidemiologic data, but also chapters on presenting scientific findings, dealing with newspaper and television reporters during
PATHOLOGY
Authors: J.-i. Adachi, K. Totake, M. Shirahata, K. Mishima, T. Suzuki, T. Yanagisawa, K. Fukuoka, R. Nishikawa, A. Arimappamagan, N. Manoj, A. Mahadevan, D. Bhat, H. Arvinda, B. Indiradevi, S. Somanna, B. Chandramouli, S. A. Petterson, S. K. Hermansen, R. H. Dahlrot, S. Hansen, B. W. Kristensen, F. Carvalho, S. Jalali, S. Singh, S. Croul, K. Aldape, G. Zadeh, J. Choi, S.-H. Park, S. K. Khang, Y.-L. Suh, S. P. Kim, Y. S. Lee, S. H. Kim, S. Coberly, K. Samayoa, Y. Liu, P. Kiaei, J. Hill, S. Patterson, M. Damore, S. Dahiya, R. Emnett, J. Phillips, D. Haydon, J. Leonard, A. Perry, D. Gutmann, S. Epari, S. Ahmed, M. Gurav, S. Raikar, A. Moiyadi, P. Shetty, T. Gupta, R. Jalali, J. Georges, A. Zehri, E. Carlson, N. Martirosyan, A. Elhadi, J. Nichols, L. Ighaffari, J. Eschbacher, B. Feuerstein, T. Anderson, M. Preul, K. Jensen, P. Nakaji, H. Girardi, F. Monville, S. Carpentier, M. Giry, J. Voss, R. Jenkins, B. Boisselier, V. Frayssinet, C. Poggionovo, A. Catteau, K. Mokhtari, M. Sanson, H. Peyro-Saint-Paul, C. Giannini, T. Hide, H. Nakamura, K. Makino, S. Yano, S. Anai, N. Shinojima, J.-i. Kuroda, T. Takezaki, J.-i. Kuratsu, F. Higuchi, H. Matsuda, K. Iwata, K. Ueki, P. Kim, J. Kong, L. Cooper, F. Wang, J. Gao, G. Teodoro, L. Scarpace, T. Mikkelsen, M. Schniederjan, C. Moreno, J. Saltz, D. Brat, U. Cho, Y.-K. Hong, Y. S. Lee, R. Lober, L. Lu, M. H. Gephart, P. Fisher, M. Miyazaki, H. Nishihara, T. Itoh, M. Kato, S. Fujimoto, T. Kimura, M. Tanino, S. Tanaka, N. Nguyen, G. Moes, J. L. Villano, H. Nishihara, H. Kanno, Y. Kato, S. Tanaka, T. Ohnishi, H. Harada, S. Ohue, S. Kouno, A. Inoue, D. Yamashita, S. Okamoto, M. Nitta, Y. Muragaki, T. Maruyama, T. Sawada, T. Komori, T. Saito, Y. Okada, S. B. Omay, J. M. Gunel, V. E. Clark, J. Li, E. Z. E. Omay, A. Serin, L. E. Kolb, R. M. Hebert, K. Bilguvar, K. Ozduman, M. N. Pamir, T. Kilic, J. Baehring, J. M. Piepmeier, C. W. Brennan, J. Huse, P. H. Gutin, K. Yasuno, A. Vortmeyer, M. Gunel, A. Perry, S. Pugh, C. L. Rogers, D. Brachman, W. McMillan, J. Jenrette, I. Barani, D. Shrieve, A. Sloan, M. Mehta, A. Prabowo, A. Iyer, T. Veersema, J. Anink, A. S.-v. Meeteren, W. Spliet, P. van Rijen, T. Ferrier, D. Capper, M. Thom, E. Aronica, T. Chharchhodawala, M. Sable, M. C. Sharma, C. Sarkar, V. Suri, M. Singh, V. Santosh, B. Thota, M. Srividya, K. Sravani, S. Shwetha, A. Arivazhagan, K. Thennarasu, B. Chandramouli, A. Hegde, P. Kondaiah, K. Somasundaram, M. Rao, V. Santosh, V. P. Kumar, B. Thota, A. Shastry, A. Arivazhagan, K. Thennarasu, P. Kondaiah, A. Shastry, R. Narayan, B. Thota, S. Somanna, K. Thennarasu, A. Arivazhagan, V. Santosh, A. Shastry, S. Naz, B. Thota, K. Thennarasu, A. Arivazhagan, S. Somanna, V. Santosh, P. Kondaiah, S. Venneti, M. Garimella, L. Sullivan, D. Martinez, J. Huse, A. Heguy, M. Santi, C. Thompson, A. Judkins, Z. Voronovich, L. Chen, K. Clark, M. Walsh, J. Mannas, C. Horbinski, B. Wiestler, D. Capper, T. Holland-Letz, A. Korshunov, A. von Deimling, S. M. Pfister, M. Platten, M. Weller, W. Wick, G. Zieman, C. Dardis, L. Ashby, J. Eschbacher
Journal: Neuro-Oncology (2013)
Data Errors in Tables 1 and 2
Authors: Howard Steinman, Anthony Dixon, Christopher Zachary
Journal: JAMA Dermatology (2019)

Kexiang Yan, MD, PhD; Yuanjing Zhang, MD; Ling Han, MD, PhD; Qiong Huang, MD, PhD; Zhenghua Zhang, MD, PhD; Xu Fang, MD; Zhizhong Zheng, MD, PhD; Nikhil Yawalkar, MD; Yuling Chang, MD; Qun Zhang, MD; Ling Jin, MD; Danfeng Qian, MD; Xueying Li, MD; Mingshun Wu, MD; Qiaohu Xu, MD; Xuejun Zhang, MD, PhD; Jinhua Xu, MD, PhD
Great Increase of Street Accidents Due to Motor Traffic
Journal: JAMA (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Experimental Subjects
Authors: Joseph L. Lombardi
Journal: JAMA (1977)

<h3>To the Editor.—</h3> In a recent issue ofThe Journal(235:2197,1976), a short essay by Richard McCormick, SJ, endorsed the removal of the ban on minimum-risk nontherapeutic research on the fetus in utero. McCormick also seems to advocate a governmental right to draft fitting adult subjects for minimum-risk nontherapeutic experimentation. The following comments focus on the first of these issues. McCormick tries to prove that<i>both</i>therapeutic<i>and</i>minimum-risk non-therapeutic experiments are within the range of things to which parents can consent by proxy for their offspring in utero. He argues that a person ought to choose "the good of life." This, presumably, entails that a person ought to choose to subject himself to those treatments that might help to preserve his life, eg, therapeutic experiments. Furthermore, if someone ought to choose something, then if he is incapable of choosing it himself, his proxies can legitimately choose it for him.
STUDIES ON RABBIT LYMPHOCYTES IN VITRO
Authors: Stewart Sell
Journal: The Journal of Experimental Medicine (1967)

Sheep antisera specific for the three major immunoglobulin groups of the rabbit, i.e. IgG (γ-chain), IgA (α-chain), and IgM (µ-chain), are each able to induce blast transformation of the peripheral lymphocytes of the rabbit when added to in vitro cultures. The per cent of lymphocytes transformed with each antiserum indicate that one-fourth of the peripheral lymphocytes carry or have the capacity to synthesize molecules of all three of the major immunoglobulin groups, and that the remaining three-fourths carry or have the capacity to synthesize only two (IgG and IgM). The data do not permit direct conclusions concerning the ability of a single cell to produce molecules belonging to more than one immunoglobulin group at the same time, or the ability of a given cell to make a transition from the synthesis of molecules of one immunoglobulin group to those of another group.
BOOK REVIEWS
Authors: R. AMBINDER
Journal: JNCI Journal of the National Cancer Institute (1989)

BOOK REVIEWS Get access Advances in Viral Oncology, Volume 8: Tumorigenic DNA Viruses. George Klein, ed. New York: Raven Press, 1989, 273 pp. $99. RICHARD AMBINDER RICHARD AMBINDER 3-121 Oncology, The Johns Hopkins Hospital, Oncology Center600 N. Wolfe St., Baltimore, MD 21205 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 81, Issue 23, 6 December 1989, Pages 1833–1834, https://doi.org/10.1093/jnci/81.23.1833 Published: 06 December 1989
Blood-Pressure in Surgery, An Experimental and Clinical Research. The Cartwright Prize Essay for 1903.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal