tbuckley/cabot-search huggingface dataset:
Hepatitis C micro-elimination pilot strategy in Pakistani migrants in Catalonia through the implementation of a community intervention: interim results of the HepC-link study
Authors: Jordi Gómez i Prat, Hakima Ouaarab, Tahir Rafi, Verónica Saludes, Sara González-Gómez, Adrian Antuori Torres, Maria Buti, Mar Riveiro Barciela, Luisa Roade, Blanca Borrás, Laia Egea-Cortés, Laia Ferrer, Juliana Reyes-Ureña, Xavier Major, Elisabeth Buira, Joan Colom, Jordi Casabona, Elisa Martró
Journal: Journal of Hepatology (2020)
About Abortion
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
'Old' Edna
Authors: Bhagwan Satiani
Journal: JAMA (1983)

She smiled in pain. She held my hand and said, "You have to make my foot better so I can walk again!" I made a noncommital gesture and started with a history. She had been having ischemic rest pain in her right foot for the past month, making it impossible for her to walk or sleep at night. She said she was "worn out" from lack of sleep. "The pain is so bad, I wish I didn't have my foot." Physical examination confirmed severe arterial ischemia, with femoral-popliteal occlusive disease. I told her I would discuss this problem further with her family physician, to which she replied, "It's my leg, not his. I want to walk again and sleep peacefully. I know I'm 91 years old and have a bad heart, but I'm sharp. Can you do something besides take my leg off?" After discussion with her family physician, who
PARAPSORIASIS.*
Authors: J. M. H. MacLeod
Journal: British Journal of Dermatology (1932)

Journal Article PARAPSORIASIS. Get access J. M. H. MacLeod J. M. H. MacLeod Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology and Syphilis, Volume 44, Issue 12, 1 December 1932, Pages 569–576, https://doi.org/10.1111/j.1365-2133.1932.tb09561.x Published: 01 December 1932
Evaluating health hazards from military lasers
Authors: D. H. Sliney
Journal: JAMA (1970)

Although most lasers are in scientific research laboratories, a growing number are finding their way into field use in the military, and their associated ocular hazards have been of concern. Laser hazards are easier to define and control in the laboratory than in the field. This results from uncertainties introduced by atmospheric effects upon the laser beam and the potential observer's use of optical instruments. These physical uncertainties, coupled with the absence of clear-cut ocular injury threshold data, make exact determinations of hazardous range quite difficult. Therefore, laser range hazard control is generally achieved by the use of backstops and in some instances by the use of protective eyewear.
Consensus conference. Anesthesia and sedation in the dental office
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phase II study of PX-866 in recurrent glioblastoma.
Authors: Marshall W. Pitz, Elizabeth A. Eisenhauer, Mary Valeria MacNeil, Brian Thiessen, David R. Macdonald, Jacob C. Easaw, David Daniel Eisenstat, Ankineedu Saranya Kakumanu, Jeremy Squire, Ming Sound Tsao, Suzanne Kamel-Reid, Aurelie Tassignon, Diana Felice Hausman, Warren P. Mason
Journal: Journal of Clinical Oncology (2013)

2053 Background: Glioblastoma (GBM) is the most aggressive malignancy of the central nervous system. The majority have genetic changes that increase the activity of the phosphatidylinositol-3-OH kinase (PI3K) signal transduction pathway, critical for cell motility, proliferation, and survival. We present the results of PX-866, an oral PI3K inhibitor, in patients (pts) with recurrent GBM. Methods: A multinomial design of response and early progression (&lt; 8 weeks on study) was used. In stage 1 (15 pts), 0 responses and ≥ 10 early progressions would stop accrual; after full accrual, ≥ 4 responses OR ≤ 13 early progressions was prespecified as of interest. Pts with histologically confirmed GBM, at first recurrence after chemoradiation and adjuvant temozolomide were given PX-866 8 mg daily on this single-arm phase II study. MRI and clinical exam were done every cycle (8 weeks). Tumour tissue was collected for analysis of potential markers of PI3K inhibitory activity (PTEN, EGFRviii, PIK3CA mutations). Results: A total of 33 pts were enrolled, eligible and evaluable. Median age was 56 (range 35-78), 12 were female; 29 had performance status (PS) 0-1 and 4 had PS 2. Median time from initial diagnosis to enrolment was 308 days (range 141-1256). Median number of cycles was 1 (range 1-7). Thirty-two pts have discontinued therapy, 26 due to disease/symptomatic progression and 6 due to toxicity (5 LFT elevation and 1 allergic reaction). Other adverse effects (AE): fatigue (16 pts/2 grade 3), diarrhea (11 pts/5 grade 3), nausea (19 pts/1 grade 3), vomiting (11 pts/1 grade 3) and lymphopenia (29 pts/7 grade 3/4). Five pts had related serious AEs (1 LFTs, 1 GI and 3 venous thromboembolism) All pts were evaluable for response; 25 had a best response of progression, 1 had partial response (overall response rate 3%) and seven (21%) had stable disease (SD, median 7.3 months; range 3.1-13.6). Six month PFS was 17%. In preliminary analyses, no statistical association was found between SD and PTEN or EGFRviii status (results pending in 16 pts). Conclusions: PX-866 was relatively well tolerated. Overall response rate was low, and the study did not meet its primary endpoint; however, 21% of pts obtained durable stable disease. Further correlative work is required to identify the predictor of this effect. Clinical trial information: NCT01259869.
THE 1935 ANNUAL SESSION
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fatal Inflammatory Condition in a Patient with a Variant Bacterial Strain
Journal: Annals of Internal Medicine (2001)

Summaries for Patients18 September 2001Fatal Inflammatory Condition in a Patient with a Variant Bacterial StrainSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-6-200109180-00007 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Pseudomembranous colitis is an uncommon but serious inflammation of the colon that can cause diarrhea, dehydration, and even death. It occurs in some people who have been given antibiotics. These drugs destroy harmless bacteria already in the colon that prevent the growth of disease-causing organisms. Subsequent growth of a particular organism, Clostridium difficile, can cause pseudomembranous colitis. This organism produces A and B toxins that can be measured in stool samples. Doctors usually use stool tests that measure toxin A to diagnose colitis rather than stool cultures because ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “Fatal Pseudomembranous Colitis Associated with a Variant Clostridium difficile Strain Not Detected by Toxin A Immunoassay.” It is in the 18 September 2001 issue of Annals of Internal Medicine (volume 135, pages 434-438). The authors are S Johnson, SA Kent, KJ O'Leary, MM Merrigan, SP Sambol, LR Peterson, and DN Gerding.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. Previousarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoFatal Pseudomembranous Colitis Associated with a Variant Clostridium difficile Strain Not Detected by Toxin A Immunoassay Stuart Johnson , Sara A. Kent , Kevin J. O'Leary , Michelle M. Merrigan , Susan P. Sambol , Lance R. Peterson , and Dale N. Gerding Metrics 18 September 2001Volume 135, Issue 6Page: I-41KeywordsAntibioticsC difficile colitisClostridiumClostridium difficileColitisColonInflammationLaboratory testsPneumoniaToxins ePublished: 18 September 2001 Issue Published: 18 September 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Tuberculosis
Authors: Parvathi Tiruviluamala, Lee B. Reichman
Journal: Annual Review of Public Health (2002)

▪ Abstract Tuberculosis is an infectious disease caused by bacteria in the Mycobacterium tuberculosis complex. Of these, the most common species to infect humans is M. tuberculosis. The TB bacillus is an extremely successful human pathogen, infecting two billion persons worldwide; an estimated 2 to 3 million people die from tuberculosis each year. In the United States, TB rates decreased steadily at the rate of 5% per year from 1953 until 1985 when the trend reversed, with the number of TB cases peaking in 1992. Outbreaks of multidrug-resistant TB (MDR TB) were reported, and these cases were documented to be transmitted in nosocomial and congregate settings, including hospitals and prisons. AIDS patients infected with M. tb developed disease rapidly, and case-fatality rates of &gt;80% were noted in those infected with multidrug-resistant M. tb. Intensive intervention, at enormous cost, caused the number of TB cases to decline. This article discusses factors that led to the increase in TB cases, their subsequent decline, and measures needed in the future if TB is to be eliminated in the United States.
Can Mind Affect Body Defenses Against Disease? Nascent Specialty Offers a Host of Tantalizing Clues
Authors: Donald E. Risenberg
Journal: JAMA (1986)

PSYCHONEUROIMMUNOLOGY, the synthesis of data from psychiatry and immunology, provides an interesting perspective on human illness. Investigators hope that it also may uncover clues to the pathogenesis of acquired immunodeficiency syndrome (AIDS). "This field of behavioral immunology is one of the most exciting developments in recent years and promises to yield great insight into the relationships between psychological factors... and the disease process," says Steven F. Maier, PhD, professor and chair of experimental psychology at the University of Colorado, Boulder. Maier and coworkers have performed animal experiments that suggest a link between stress and immune function and indicate the importance of the subject's sense of control in a stressful situation. In one experiment, three groups of laboratory rats were given a series of inescapable electric shocks, escapable shocks, or no shocks, respectively (<i>Science</i>1983;221:568-570). Lymphocyte proliferation, in response to phytohemagglutinin and concanavalin A (in vitro stimuli), was then measured. Those
HOTEL ACCOMMODATIONS—IMPORTANT.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE ESKRIDGE-PARKHILL MEMORIAL.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pasteurella Endocarditis
Authors: Gordon L. Doty, Gerald N. Loomus, Paul L. Wolf
Journal: New England Journal of Medicine (1963)

THE genus pasteurella includes a group of organisms having somewhat similar morphology, cultural characteristics and antigenic structure. The virulence of the group varies widely from the extremely virulent Pasteurella pestis to the relatively benign Past, multocida and Past, haemolytica. Past, haemolytica infection in man is extremely rare. The case of bacterial endocarditis with perforation of a mitral-valve leaflet caused by this organism reported below is to our knowledge the first case recorded in the medical literature in English.Case ReportM.G., a 54-year-old woman, was taken to the hospital on May 25, 1962, by her sister because of diarrhea . . .
PATTERNS OF VIOLENCE
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Career decisions of unaccepted applicants to Medical School
Authors: D. M. Levine
Journal: JAMA (1975)

To investigate the admissions process to medical school and the post-rejection behavior of unaccepted applicants, a national sample of the 16,837 such applicants to the entering medical school class of 1971-1972 was studied in 1973. The majority of the 1,933 respondents had reapplied to medical school following rejection, and 27% had gained entrance to either US or foreign schools by the time of the study. Of those still unaccepted, about half were studying or working in health-related fields of study or occupations at least 2 1/2 years following the initial rejection. We conclude that unaccepted applicants demonstrate considerable variance in postrejection behavior, which is associated with both personal and institutional factors. (<i>JAMA</i>232:1141-1143, 1975)
FORMATION OF BILE PIGMENT WITHOUT THE LIVER
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sunlight and the skin
Authors: I. Willis
Journal: JAMA (1971)

To avoid the sun would be to exist without one of the great pleasures of life. But, as with most enjoyable things, indiscriminate exposure can result in unhappiness and even serious illnesses. The undesirable results of "solar indiscretions" have been recognized from the earliest times. Scientific and medical investigations of the subject have evolved into a field known as clinical dermatologic photobiology, pioneered in the United States around the 1930's by such investigators as Blum, Epstein, Sulzberger, Stokes, and Rothman. Through the use of modern solar simulating lamps, ultraviolet (UV) light filters, and monochromators in improved diagnostic test procedures, recent investigators have accomplished much toward a better understanding of the pathogenesis of sunlight-induced skin disorders.<sup>1</sup>This new knowledge has permitted increasingly better approaches to the treatment and prevention of these disorders. The purpose of this communication is to describe the most common types of sunlight-induced skin disorders, with special
Substitute for Glass Cover-Slips
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal