tbuckley/cabot-search huggingface dataset:
THE CRITERIA OF SENILITY.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE COMPLEMENTAL FEEDING OF THE NEW-BORN
Journal: JAMA (1924)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Survival and treatment trends for advanced colorectal cancer (CRC) treated in a University Hospital, 1992–2001
Authors: T. J. Price, K. Pittman, K. Patterson, M. Colbeck, S. Sim, D. Roder, N. Rieger, P. Hewett, G. Maddern, C. Luke
Journal: Journal of Clinical Oncology (2004)

3707 Background: Over the last decade significant improvements in the outcome for patients with advanced CRC has been achieved. We have reviewed the prospective CRC database at our hospital from 1992 to 2001 to explore whether the availability of new chemotherapy drugs (irinotecan and oxaliplatin) and surgical advances has impacted on survival. Method: Two time periods were analysed: 1/1/92- 31/12/97 & 1/1/98–12/31/01 reflecting the availability of these new drugs in Australia. Two distinct patient groups for each period were analysed; advanced disease (Ad) at diagnosis & patients with Dukes A, B & C disease (abc) at recurrence. Results: There were a total of 541 cases diagnosed with advanced or recurrent CRC available for baseline characteristics. Treatment received is shown in table 1. & has both altered & increased with time, although overall chemotherapy use remains relatively low. The percentage of relapsing v advanced disease reduced over time. The overall 18 month survivals pre & post 98 are as follows; 92–97 - 33.3% (+3.9), 98–01 - 49.0% (± 5.0). Median survivals were; 92–97 - 11.2 months, 98–01 - 15.1 months. Survival specifically for the abc group was higher for those diagnosed after 1998 (RR 0.63, 047–0.85). The 36 month survival for this group was 23% v 44%. Conclusions: These data suggest that a number of factors have contributed to the trend of improved survival & these include improved access and availability of effective chemotherapy, increased hepatic resection rates, second line chemotherapy & improved staging diagnosing patients with advanced disease earlier, ie stage migration. Additional data will be presented. No significant financial relationships to disclose.
Correlation of baseline serum testosterone (T) and serum prostate-specific antigen (PSA) at 7 months (7 mo PSA) in patients (pts) with new hormone sensitive metastatic prostate cancer (mHSPC) treated with continuous androgen deprivation therapy (cADT).
Authors: Shiven B. Patel, Tyler Howard Buckley, David Gill, Srinivas Kiran Tantravahi, Julia A. Batten, David D. Stenehjem, Anitha Alex, Neeraj Agarwal
Journal: Journal of Clinical Oncology (2015)

e16019 Background: Based on data from > 1,000 men with new mHSPC undergoing ADT in the SWOG-9346 study, a failure to achieve a 7 mo PSA of ≤4 ng/mL, is a powerful negative predictor of survival (Hussain et al., JCO 2006). Following baseline clinical variables predicted lack of achieving 7 mo PSA ≤ 4.0 ng/mL: decreased age, initial PSA, weight loss, bone pain, poor performance status, and Gleason sum ≥ 8. We hypothesized that the baseline serum T is also an independent predictor of 7 mo PSA. Methods: Eligible pts were identified from an institutional database. The association of baseline clinical and disease characteristics with 7 mo PSA were analyzed using multivariate regression model (Table). Results: 62 pts were eligible for inclusion. 43% achieved undetectable 7 mo PSA, and 28% had a 7 mo PSA ≥ 4 ng/mL suggesting a representative population, similar to that in the SWOG-9346 study. Significant association between covariates and 7 mo PSA was observed (Prob > F = 0.0237; R2 = 0.351). Baseline serum T and PSA were independent predictors of 7 mo PSA. Baseline serum T, as a continuous variable, showed negative correlation with 7 mo PSA, while baseline PSA showed a positive correlation (Table). Conclusions: Baseline serum T independently predicts 7 mo PSA. Pts with new mHSPC with lower baseline T may have improved outcomes with deeper androgen blockade with ADT along with a 17,20-lyase and 17-alpha-hydroxylase inhibitor or a second generation androgen receptor inhibitor at the time of induction. Data need further validation in a larger cohort. (SP and TB equal contribution). Multivariate regression model predicting 7 mo PSA in new mHSPC patients undergoing ADT (n=62). Baseline covariates Coefficient Std Error P 95 % CI Age 1.171 2.454 0.636 -0.381 to 6.154 Testosterone -1.707 0.787 0.037* -3.305 to -0.110 PSA 0.586 0.243 0.021* 0.093 to 1.079 Gleason score 3.978 2.582 0.133 -1.266 to 9.221 ECOG 0.226 0.346 0.519 -0.477 to 0.929 Bone pain -0.325 0.376 0.395 -1.090 to 0.440 Visceral metastasis 0.909 0.709 0.208 -0.531 to 2.350 *, P< 0.05
Entero-Vioform for preventing travelers' diarrhea
Authors: M. G. Schultz
Journal: JAMA (1972)

Travelers' diarrhea can be an unpleasant complication of a business or vacation trip abroad. The prospect of succumbing to the "Aztec two-step" or "Delhi belly" causes more anxiety on the part of the prospective traveler than any other health-related aspect of his trip. Because means are available for preventing malaria, smallpox, typhoid, and other more serious threats to the traveler, his natural inclination is to take something he thinks will protect him from diarrhea. The drug most commonly used for this indication is iodochlorhydroxyquin (Entero-Vioform), and over the years it has become the travelers' vade mecum. In this issue ofThe Journaltwo letters (p 275) and a case report (p 243) raise the issues of the safety and efficacy of iodochlorhydroxyquin. With the vacation season approaching, physicians should be aware of the controversy concerning iodochlorhydroxyquin and the best methods to prevent travelers' diarrhea. Diarrhea in travelers occurs most commonly
Cardiac Aneurysm
Authors: Max Caplan, Paul M. Sherwood
Journal: New England Journal of Medicine (1949)

PRIOR to 1931, the diagnosis of acquired aneurysm of the left ventricle was made only ten times ante mortem.1 , 2 With the better appreciation of the significance of the clinical features of this condition and the increased use of modern diagnostic facilities, more and more cases have been reported in the literature, and a new evaluation of the prognosis is warranted. Thus, although in Parkinson, Bedford, and Thomson's3 cases, the longest survival was thirty months, in Dressier and Pfeiffer's4 cases it was seven years. Young and Schwedel5 have reported the case of a patient who survived for ten years after the . . .
Can determination of the proliferative capacity of the nontumor portion predict the risk of tumor recurrence in the liver remnant after resection of human hepatocellular carcinoma?
Authors: J Chiu
Journal: Hepatology (1993)

To test the hypothesis that increased proliferative capacity of cells in a liver remnant is a risk factor for tumor recurrence in patients who have undergone liver resection for hepatocellular carcinoma, DNA flow-cytometric measurement and cell-cycle analysis of the nontumor parts of resected hepatocellular carcinomas (tumor size <5 cm) were performed. The disease-free survival rates 1, 2, 3 and 4 yr after surgery were 64%, 58%, 43%, and 36%, respectively. Proliferative capacity (fractions of synthetic, postsynthetic and mitotic phases) of the nontumor parts, irrespective of liver pathology, was higher than that of normal liver and statistically lower than that of tumor parts from resected hepatocellular carcinoma specimens. Livers with chronic active hepatitis and with hepatocyte dysplasia had significantly lower proliferative activity than did those with chronic active hepatitis and with hepatocyte dysplasia. We saw no significant difference in proliferative capacity between patients with and without cirrhosis. Disease-free-survival analysis showed that the presence of liver pathology (hepatitis B infection, cirrhosis, chronic active hepatitis and hepatocyte dysplasia) was not the factor linked to tumor recurrence in the liver remnant and that a marked increase in proliferative capacity (≥ 18%), regardless of liver pathology, was the risk factor linked to tumor recurrence after liver resection. We conclude that there is some degree of increased proliferative capacity in the nontumor parts of resected hepatocellular carcinomas and that a marked increase in the proliferative capacity (≥ 18%) of the nontumor part is a significant risk factor in predicting tumor recurrence in the liver remnant after liver resection. (HEPATOLOGY 1993;18: 96–102).
Care of Certified Psychiatric Patient in General Hospital
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Difference between antinuclear antibody-positive non-alcoholic steatohepatitis and autoimmune hepatitis based on differential patterns of peripheral T lymphocytes
Authors: Akira Kado, Takeya Tsutsumi, Kazuhiko Ikeuchi, Kazuya Okushin, Kenichiro Enooku, Hidetaka Fujinaga, Kyoji Moriya, Hiroshi Yotsuyanagi, Kazuhiko Koike
Journal: Journal of Hepatology (2020)
MONOMACHY WITH CHOLESTEROL
Journal: JAMA (1960)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Antibodies to silicone detected in patients with severe inflammatory reactions
Authors: T. Randall
Journal: JAMA (1992)

SOME PATIENTS may be capable of mounting specific immune responses to silicone, new research suggests. Researchers have detected increased levels of antibodies specific to silicone in the sera of two patients. Both had severe, chronic inflammatory reactions around implanted Silastic ventriculoperitoneal shunt tubing. Neither had infections that otherwise might have explained the inflammation (<i>Lancet</i>. 1992; 340:510-513). Historically, silicone materials have been generally thought to be immunologically inert. The August 29<i>Lancet</i>article is "the first published study to demonstrate specific immune reactants capable of recognizing silicone material," says first author Randall Goldblum, MD, professor of pediatrics, and human biological chemistry and genetics at the University of Texas Medical Branch at Galveston. The other authors are Galveston researchers Ronald Pelley, MD, Alice O'Donell, MD, Debra Pyron, and John Heggers, PhD. Goldblum and his colleagues detected the antibodies with a modified enzymelinked immunosorbent assay (ELISA), in which Silastic tubing serves as the
Healing Arts
Authors: Lisa M. Lanzarone
Journal: JAMA (1991)

The ritual that gets me through the day starts with a jolt from REM sleep. First sound of the day: static from the clock-radio. First thought: another day of this dehumanizing internship. First sight: a whitewashed, empty face in the mirror. This is me. My mind has abandoned its search for meaning in my work on the medical wards. The Fraternity that is Medicine, like all the others, requires that members must survive rituals of pain before they can enter the fold. But the human organism knows that repeated trauma causes the skin to lose sensation; the only protection is respite, which is not my privilege this morning. I cannot recall exactly when I gave up the search and wonder if numbness has begun to shape my thoughts. Still, internship is only a year, almost half over; residency will be an improvement. By then I might enjoy leading everyone on
Incorrect Values and Missing Sentence.
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Rates of pneumonia during influenza epidemics in Seattle, 1964 to 1975
Authors: H. M. Foy
Journal: JAMA (1979)

Influenza A epidemics were associated with a doubling to tripling of pneumonia rates among adult members of a prepaid medical care group studied between 1963 and 1975. Rates of influenza A associated with pneumonia increased with age. Influenza B epidemics did not have a similar effect. Overall pneumonia rates were highest in children younger than 5 years, but in this age group, other respiratory viruses dominated as causative agents. Influenza A and B epidemics were not always synchronized with those reported for the United States, and rates of influenza A infection varied between urban and suburban areas in sequential epidemics. In 1974, a year practically free from influenza A, a prolonged<i>Mycoplasma pneumoniae</i>epidemic kept rates of pneumonia high, especially during the summer. (<i>JAMA</i>241:253-258, 1979)
Clinical Lectures Delivered at University College Hospital
Authors: J. Erichsen
Journal: BMJ (1860)

GENTLE31EN,-There have been lately under your notice two cases illustrating in a marked manner the most interesting points of disease in the neighbourhood of the hip-joint.The first of these is that of a woman, aged 23, who was sent up to me by Mr. Barher of Smardon, for disease about the hip-joint, with the following history.She is delicate: both her parents and one brother died of consumption.During early childhood, she had an abscess near the right hip, which healed up after some months, and gave no further trouble, and left no diffi- culty in moving the thigh.In addition to this, there was also during childhood disease of the lower end of the tibia, the position of which is now marked by a cicatrix.About six months ago, after a fall in which she struck the right hip, the part became swollen and painful, the old cicatrix opened, and matter escaped.The aperture has continued to discharge up to the present time.On admission, the movements of the joint, though limited, were found to be perfect, and gave rise to no pain except what was due to the state of the soft parts around.The limb is in its natural position; but the patient cannot walk or even bear upon it, on account of a feeling of weakness in it.There is a quarter of an inch of shortening; but this is between the knee and ankle, and is evidently due to the disease of the lower epiphysis of the tibia in childhood, -and not to the state of the hip.Nearly opposite the insertion of the tensor vagince femoris muscle, there is a sinus which discharges a considerable quantity of thin pus.A probe passed along this strikes and passes deeply into carious bone, apparently situated in the trochanter; whilst behind that process is a cavity containing pus, in which the probe turns freely, and runs up beneath the gluteal muscles to some distance.
Bone Marrow/Stem Cells: No Edge in Breast Cancer
Authors: J. Stephenson
Journal: JAMA (1999)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A gifted teacher and storyteller writes about his medical adventures
Journal: JAMA (1990)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal