tbuckley/cabot-search huggingface dataset:
Air controller strike spotlights job stress
Authors: P. Gunby
Journal: JAMA (1981)

The current air traffic controllers' strike, now entering its third month, has become the focal point of an issue that is receiving increasing medical attention these days: job-related stress. The striking air controllers say that their job responsibilities occasionally induce almost unbearable stress and that this pressure threatens their health and sometimes the safety of those flying in the airplanes that they supervise. But the Federal Aviation Administration (FAA) contends that the matter of the controllers' jobrelated stress has been blown out of proportion. Spokesmen for the FAA say that efforts are continuing to minimize stress. They add that, moreover, the controllers' jobs may be very different before many more years pass. Also at this time, coincidentally or not, the National Center for Health Statistics in Hyattsville, Md, has finished analyzing data on job stress collected in a 1979 survey. According to center statisticians, about one in four (26.5% ) American
Factors influencing death at home in terminally ill patients with cancer: systematic review
Journal: BMJ (2006)

in the academic reference.Powis et al found that interviewers' negative remarks had weak predictive value for course withdrawal, 7 and Papadakis et al suggested some correlation between negative statements regarding unprofessional undergraduate behaviour and later disciplinary action in graduates. 8In view of our results, statement review remains an integral part of our admissions process.Similarly, we are not aware that others have examined the timing of course offers in relation to undergraduate progress. Future policy and researchMany medical schools in the United Kingdom are exploring more varied admissions policies, perhaps incorporating elements of the successful Australian policies of lower examination grades accompanied by psychometric testing. 3Their outcome evaluations, especially in relation to non-traditional students, may be important in guiding future policy across the UK. 2 9 Our data suggest that the current four stage approach to student selection is sound, but we now have concerns that the introduction by UCAS of open references will reduce the opportunities for head teachers to draw attention to personal qualities or difficulties that might make it difficult for a student to succeed in medicine.A structured reference might be more helpful.Pastoral support at Nottingham includes informal meetings with personal tutors and more intensive formal mechanisms, yet some students still hide, or deny, their difficulties until they reach a crisis point.In the course of this research we noticed a high incidence of depressive illnesses in strugglers, which is of particular concern.We intend to review our strugglers and our pastoral practices more closely to see what further support could be offered, perhaps as targeted interventions to those at greatest risk.Research elsewhere has identified personal, social, cultural, and financial pressures that may particularly affect students from non-mainstream backgrounds and that may need to be addressed explicitly and proactively. 10 11Failure in clinical examinations may have a sex related or cultural basis because the current emphasis on patient centred, empathetic care may be more natural for women than for men 12 and may present a considerable difficulty for students from more paternalistic cultures. 13Language barriers may be important because fluency in standard English may not be adequate for medical and colloquial needs. 14 We plan further investigations into the nature of negative comments and the characteristics and difficulties of those who do less well on the course.
PLoS Medicine Issue Image | Vol. 7(4) April 2010
Journal: PLoS Medicine (2010)

This month's Editorial, a collaborative statement by editors from Medical Decision Making, Trials, The Cochrane Library, Journal of Clinical Epidemiology, and PLoS Medicine, calls for standards in the conduct and reporting of comparative effectiveness research (CER). To optimize health outcomes within the constraints of inevitably limited resources, low- and high-income countries alike require unbiased means of assessing health care interventions for their relative effectiveness. Providing specific principles and standards for CER, the journal editors emphasize that researchers must adopt stringent methods, and medical journals must maintain high criteria for ethics, scientific rigor, and reporting, in order to fulfill the potential of research to improve decision making in health care. This statement has also been endorsed by the editors of Journal of General Internal Medicine, The American Journal of Managed Care, Clinical and Translational Science, and Croatian Medical Journal, and will be co-published in Medical Decision Making, Croatian Medical Journal, The Cochrane Library, Trials, The American Journal of Managed Care, and Journal of Clinical Epidemiology. Image Credit: Collage created by Katie Hickling, PLoS. Original images by southerntabitha, taberandrew, FeatheredTar, Seattle Municipal Archives, VinceHuang, jen_rab, isafmedia, and dbdbrobot, all on flickr.com.
Botulism
Authors: Luther L. Terry, Senator Philip A. Hart
Journal: JAMA (1964)

<h3>To the Editor:—</h3> I read with considerable interest the editorial on botulism, "The Most Deadly Poison" (<i>JAMA</i><b>187</b>:530). I was especially gratified by your commendation of the Public Health Service role in combatting the recent outbreaks. The service has taken further actions to improve our readiness capability to assist physicians and hospitals when these outbreaks occur. Our Communicable Disease Center in Atlanta has recently procured from the Danish State Serum Institute a limited supply of antitoxin for emergency use by qualified medical practitioners against type E botulism. The Center will be on 24-hour call. Upon receipt of a request from a state health department, antitoxin will be immediately dispatched along with a PHS medical epidemiologist who will investigate the case and determine whether other cases are likely to follow. The PHS plans to purchase additional type E antitoxin from Connaught Laboratories in Toronto. Production will take 12 months or
the disappearing
Authors: Andrew Thurston
Journal: Annals of Internal Medicine (2015)

Ad Libitum18 August 2015the disappearingAndrew Thurston, MDAndrew Thurston, MDFrom Pittsburgh, Pennsylvania.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M15-0593 Audio Reading - “the disappearing” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "the disappearing," by A. Thurston. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail I.The horse was blind from cataract and scar—the brittleness of bone spread through his knees.He stopped feeding,and never ventured far.He spent the afternoons beneath the treesby the old brown fence that marked the northernland line, staring at the wood as though he—through the burning of a glare—could turnthe thing to ash, and escape.And go free.I woke one morning, young, and looked around—saw nothing standing but the fence outside;the hoof-prints—horseless—in the clotting ground."He's done it—see! He's disappeared!" I cried.And mother pulled the fiber from the corn.And father washed the sweaterhe had worn.II.I ... Author, Article, and Disclosure InformationAffiliations: From Pittsburgh, Pennsylvania.Current Author Address: Andrew Thurston, MD; e-mail, [email protected]edu. PreviousarticleNextarticle Advertisement Audio Reading - “the disappearing” Audio. Michael A. LaCombe, MD, Annals Associate Editor, reads "the disappearing," by A. Thurston. Your browser does not support the audio element. Audio player progress bar Step backward in current audio track Play current audio trackPause current audio track Step forward in current audio track Mute current audio trackUnmute current audio track 00:00/ FiguresReferencesRelatedDetails Metrics 18 August 2015Volume 163, Issue 4Page: 310KeywordsBoneForecastingKneesScars ePublished: 18 August 2015 Issue Published: 18 August 2015 Copyright & PermissionsCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
The liver-spleen scan as a quantitative liver function test: Correlation with liver severity at peritoneoscopy
Authors: John C. Hoefs, Felix Wang, Gary Kanel, Philip Braunstein
Journal: Hepatology (1995)

Sulfur colloid distribution on liver-spleen scan is determined by the perfused Kupffer cell mass. The perfused Kupffer cell mass is proportional to the perfused hepatocyte mass, but is less affected by acute changes in hepatocyte function. Thus, sulfur colloid distribution parameters (precisely measured by quantitative liver-spleen scan [QLSS]) may be an excellent test of the perfused hepatic mass. Although no gold standard exists for confirmation, a close correlation should exist between liver disease severity assessed at peritoneoscopy and sulfur colloid distribution. Peritoneoscopy severity (scored as total peritoneoscopy score [PS]; range, 0-5) was assessed in 76 patients who also had QLSS. Multivariate equation were generated to estimate liver disease severity from the QLSS. These were then applied prospectively in 20 consecutive patients to validate these equations. In 76 patients, 62 were evaluated because of chronic liver disease (CLD) and included those with micronodular (20) and macronodular (20) cirrhosis with various degrees of severity (Child’s A, 16; B, 29; C, 17). Multivariate analysis yielded a number of combinations of QLSS parameters that correlated with peritoneoscopic severity. These equations were used to estimate liver disease severity. Estimates of liver disease severity (estimated PS [EPS]) correlated well with the PS in these 76 patients ( r = .9064; r 2 = .8216; P &lt; .0001). Adding histological fibrosis to the QLSS parameters yields an equation for estimating PS that was even more effective ( r = .9462; r 2 = .8953; P &lt; .001). However, validation of multivariate equations requires confirmation of their value in a second population. Applying these equations to a prospective group of 20 patients who subsequently had peritoneoscopic evaluation produced a similar correlation for QLSS parameters alone for estimating severity ( r = .870; r 2 = .757; P &lt; .0001), and this was improved when the equation including histological fibrosis was added ( r = .936; r 2 = .877; P &lt; .001). We believe these data support the QLSS as a quantitative estimate of the perfused hepatic mass that correlates with liver disease severity at peritoneoscopy. (Hepatology 1995; 22:1113-1121.).
Praktikum der wichtigsten Infektions-krankheiten
Journal: JAMA (1934)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The sick physician. Impairment by psychiatric disorders, including alcoholism and drug dependence
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Editorial: Presentation of myocardial infarction.
Journal: BMJ (1974)

Presentation of Myocardial InfarctionProspective studies have given useful information about causal factors in myocardial infarction by showing up those characteristics such as hypertension and cigarette smoking which predispose to the disease.Much less work has been done on defining the presentation of myocardial infarction in the community.While waiting for research to show us how to reduce or eliminate the causal factors, we have to plan how best to use our scarce medical resources to cope with the disease.It is the prime cause of sudden death in middle age, and often leaves severe physical and emotional disability in the survivors.Especially with the forthcoming regional co-
Response and progression in recurrent malignant glioma
Authors: K. R. Hess
Journal: Neuro-Oncology (1999)

In this article we report the results of a study of the relationship between response and progression in 375 patients with recurrent glioma enrolled in phase II chemotherapy trials.We reviewed the records of patients from 8 consecutive phase II trials, including 225 patients with recurrent glioblastoma multiforme and 150 with recurrent anaplastic astrocytoma.Median age was 45 years (range, 15-82) and median Karnofsky performance score was 80 (range, 60-100).Forty-one patients (11%) had more than two prior resections and/or more than two prior chemotherapy regimens.Best response was complete (n = 1) or partial (n = 33) in 34 patients (9%).Median time to response was 14 weeks, and median response duration was 44 weeks.Simon-Makuch estimates for 52-week progression-free survival for patients progression-free at 13 weeks were 48% for response and 28% for nonresponse.When response was treated as a time-dependent covariate in a Cox proportional hazards regression analysis, response was associated with signi cantly lower failure rates (hazard ratio 0.5; 95% con dence interval 0.3-0.8;P = 0.0016).This study showed that response in recurrent glioma is associated with a signi cant reduction in progression rates.
Adult Basic Life Support
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
House Calls by Oncologists: A Home-Visit Primer
Authors: Anand B. Karnad
Journal: Journal of Clinical Oncology (2002)

Article Tools THE ART OF ONCOLOGY: WHEN THE TUMOR IS NOT THE TARGET Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.2002.20.17.3745 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 12202677 House Calls by Oncologists: A Home-Visit Primer Anand B. KarnadxAnand B. KarnadSearch for articles by this author Show More From the Division of Hematology-Oncology, James H. Quillen College of Medicine and Veterans Affairs Medical Center, East Tennessee State University, Johnson City, TN. https://doi.org/10.1200/JCO.2002.20.17.3745 Full Text PDF Figures and Tables "House Calls by Oncologists: A Home-Visit Primer." Journal of Clinical Oncology, 20(17), pp. 3745–3746© 2002 by American Society of Clinical Oncology
Selective inhibition of the reverse transcription of duck hepatitis B virus by binding of 2',3'-dideoxyguanosine 5'-triphosphate to the viral polymerase
Authors: A HOWE
Journal: Hepatology (1996)

Hepatitis B virus (HBV) replication is mediated by the viral polymerase that possesses three functional domains: primer, DNA polymerase/reverse transcriptase, and RNase H. Using the Pekin duck as an animal model, we demonstrate a novel mechanism of inhibition of duck hepatitis B virus (DHBV) by 2,6-diaminopurine 2',3'-dideoxyriboside (ddDAPR), a prodrug of 2',3'-dideoxyguanosine (ddG). A selective and irreversible inhibition of DHBV DNA replication is found in ducklings treated with high doses of ddDAPR (20 to 50 mg/kg), but not with similar doses of 2',3'-dideoxycytidine (ddC). The inhibition mediated by ddDAPR occurs at a very early stage of the reverse transcription. Despite the inhibition of DHBV DNA replication by ddDAPR, the DNA polymerase and reverse transcriptase activities of the polymerase are found to remain active when tested on exogenous templates in activity gels. We have demonstrated direct binding of [alpha-32P]ddGTP to the DHBV polymerase expressed in an in vitro transcription and translation system. These results suggest that the binding of ddGTP to the polymerase blocks the initial DNA replication. (Hepatology 1996 Jan;23(1):87-96)
A New Tradition
Journal: JAMA (1973)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment of Warts with 5-Fluorouracil
Authors: Miles Hursthouse
Journal: British Journal of Dermatology (1970)

Journal Article Treatment of Warts with 5‐Fluorouracil Get access Miles Hursthouse Miles Hursthouse 16 Nile Street, Nelson, New Zealand Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 83, Issue 1, 1 July 1970, Page 218, https://doi.org/10.1111/j.1365-2133.1970.tb12888.x Published: 01 July 1970
Eugenics
Journal: JAMA (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Vasospasm — Ubiquitous?
Authors: Jay D. Coffman, Richard A. Cohen
Journal: New England Journal of Medicine (1981)

IN this issue of the Journal, Miller et al. report on a remarkable correlation of migraine headaches, Raynaud's phenomenon, and variant angina, and they imply that vasospasm occurs in three different vascular beds in patients with these disorders. The title of their paper is appropriately posed as a question, for vasospasm is not a proved component of each condition.If confirmed, this interesting clinical correlation could stimulate new avenues of research. The cause and pathogenesis of vasospasm remain enigmatic. It is probable that there is more than one cause and that it depends on activation mechanisms different from those . . .