tbuckley/cabot-search huggingface dataset:
DIASTOLIC BLOOD PRESSURE--A CORRECTION
Journal: BMJ (1910)

At page 1390, second column, line 38, I say, " Its relation to systolic tension . . . is nearly 1 to 4." The "1 its " here refers to the difference between systolic and diastolic pressure, or pulse pressure, mentioned at the end of the preceding paragraph.But it might be supposed to refer to " diastolic pressure " mentioned at the beginning of the preceding paragraph, and in this case is apparently in contradiction to the statement in line 45 that the relationship of the diastolic to the systolic pressure is as 3 to 4. If the readers of my address will correct it by substituting " The relation of pulse pressure to systolic tension" instead of " Its relation to systolic tension " that ambiguity -will disappear.-Withmany apologies, [ am, etc., London, W..
Teaching nutrition.
Journal: BMJ (1972)

of neoplasms and the meaning of pathological terms.Thus, "restorative hyperplasia" is regarded as a better term than "regeneration," and "nodular hyperplasia" is preferred to "regeneration nodules."A particularly important recom- mendation is that, in relation to liver cancer in man, priority should now be given to assessing the role of known or suspected hepatocarcinogens rather than to in- creasing the already bewilderingly large number of liver carcinogens listed during the conference by G. P. Warwick.'
Cancer trends among the extreme elderly in the era of cancer screening.
Authors: Shannon Nicole Ryemon, Ronald D. Ennis, Jessica E. Gross, Benjamin Philip Levy, Michael L. Grossbard, Daniel Jacob Becker
Journal: Journal of Clinical Oncology (2014)

e17631 Background: The extreme elderly (>85 years) are among the fastest growing segments of the population and bear a substantial cancer burden. Early detection by screening has the potential to decrease the incidence and mortality of cancer among the elderly. We studied cancer incidence and mortality changes among the extreme elderly (EE) during the implementation of widespread cancer screening. Methods: We examined the SEER database for incidence and mortality rates by age group between 1973 and 2009. We evaluated cases of breast, colon, prostate, and lung cancer and compared changes in incidence and mortality between EE patients and middle aged (MA) patients (50-69 years). We used SEERSTAT and Joinpoint regression software to quantify trends in the data. Results: Prostate cancer incidence and mortality rose for the EE in the 1980’s, and began to decline in the early 1990’s (-3.61%/year [95% CI: -4.29; -2.92] for incidence; and -2.91%/year [CI:-3.22; -2.59] for mortality). Prostate cancer incidence rose steadily throughout the study period for MA patients. Breast cancer incidence rose and then declined for both MA and EE patients, with the decline starting in 1990 for the EE (-1.34%/year [CI: -1.65; -1.03]), and 1998 for the MA (-1.24%/year [CI:-1.81; -0.67]). Both age groups experienced an increase and then decrease in colon cancer incidence. Decrease in colon cancer mortality over the last decade was profound for all patients (-2.88%/year [CI: -3.43; -2.14] for MA; and -3.29%/year [CI:-3.68; -2.90] for EE). Both incidence and mortality from lung cancer increased throughout the study for the EE (+2.35%/year [CI:2.21; 2.49] for incidence to 2005; +1.25%/year, [CI:1.05; 1.45]) for mortality 1995-2009). Lung cancer incidence and mortality increased and then decreased for MA patients (-2.54%/year [CI:-2.68, -2.41] for mortality from 1990). Conclusions: Recent trends in incidence and mortality for screened cancers (breast, colon, prostate) show tremendous gains for the extreme elderly. Incidence and mortality from lung cancer have continued to worsen for the extreme elderly, despite improvements in younger patients. Additional focus on screening, treatment, and exposure is warranted to lessen the burden of lung cancer in the extreme elderly.
AIDS commission's next report focuses on four critical issues
Authors: C. Marwick
Journal: JAMA (1988)

THE PRESIDENTIAL Commission on the Human Immunodeficiency Virus (HIV) Epidemic plans to issue a report next month that addresses key issues. In the meantime, it has issued its first report and sent it to the White House. Essentially, this first report is—as the commission puts it—a road map intended to guide the members' work over the next six months to the end of June, when it will issue still another report-its final one. In his letter transmitting the first interim report, the commission's chair, Admiral (Retired) James D. Watkins, identified four critical issues that, he says, "cry for early resolution." Watkins says the commission will continue to take testimony on these issues (the latest round of public hearings began Dec 10) in the next few weeks. It will form the topic of the further interim report that the commission intends to issue next month. These issues are as follows: (1)
HYBRID-BIOPSY ENDOSCOPIC MUCOSAL RESECTION: AN EFFECTIVE AND SIMPLE TECHNIQUE FOR FLAT COLORECTAL LESIONS
Authors: M Fraile-López, A Jawhari, S Sansone, S Budihal, A Parra-Blanco
Journal: Endoscopy (2019)

Hybrid resection techniques (Hybrid EMR-Hybrid ESD) have been described to facilitate complete removal of flat lesions. They may be useful in cases when the snare slips, which may happen in Laterally-Spreading lesions of the non-granular type (LST-NG), fibrosis due to previous resection attempts, and fatty tissue in the submucosa among other factors. However, endoscopists not experienced in ESD may not feel confident doing a circumferential incision with a dedicated knife or the tip of a snare, and it would not be safe if they are not adequately trained in this technique.
INCIDENCE AND CLINICAL IMPACT OF LONGITUDINAL STENT DEFORMATION AFTER THE PROMUS ELEMENT PLATINUM CHROMIUM-EVEROLIMUS ELUTING STENT IMPLANTATION
Authors: Takashi Hiromasa, Shoichi Kuramitsu, Takenori Domei, Makoto Hyodo, Yoshimitsu Soga, Shinichi Shirai, Kenji Ando
Journal: Journal of the American College of Cardiology (2017)
No Evidence of Relation Between Maternal Exposure to Herpes Simplex Virus Type 2 and Risk of Schizophrenia?
Authors: Alan Brown
Journal: American Journal of Psychiatry (2006)

Objective: The authors examined whether maternal exposure to herpes virus type 2 is associated with risk for adult schizophrenia. Method: The authors studied a large birth cohort, born 1959–1967, with follow-up for schizophrenia from 1981 through 1997. Sixty patients were diagnosed with schizophrenia and other spectrum disorders; 110 comparison subjects had no schizophrenia spectrum or major affective disorders and were matched to patients by date of birth, gender, time in the cohort, and availability of maternal sera. Archived maternal sera of patients and comparison subjects from late pregnancy were assayed by enzyme-linked immunosorbent assay for immunoglobulin (IgG) antibody to herpes simplex virus type 2. Results: The authors found no associations between maternal IgG seropositivity or antibody levels to herpes simplex virus type 2 and risk of schizophrenia. Conclusions: The authors found no support for a relationship between prenatal herpes simplex virus 2 type exposure and risk of schizophrenia.
Underdiagnosis of Depression in Primary Care: By Accident or Design?-Reply
Authors: Robert M. A. Hirschfeld
Journal: JAMA (1997)

<h3>In Reply.</h3> —I wish that in our article we were able to state as poignantly and as articulately the points raised by Dr Bell. His years in the practice of medicine come through loud and clear from his comments. Bell's letter illustrates the continuing consequences of the stigmatization of depression and other psychiatric illnesses. Discrimination against those with depression, such as being rated or refused insurance, must be stopped. We must also strive to address the massive assault on confidentiality of medical records, including psychiatric records. Dr Berger describes the consequences of misinformation about and stigmatization of depression. He points out, in a very practical manner, that education and information can foster compliance with effective treatment recommendations. He suggests that we consider a change of term from "depression" to something that the public will identify as a medical disorder. It is a noble thought, but I doubt that it would be effective.
Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands
Authors: Hubert C. Chen, Steven J. Smith, Bryan Tow, Peter M. Elias, Robert V. Farese
Journal: Journal of Clinical Investigation (2002)

Acyl CoA:diacylglycerol acyltransferase (DGAT) is a ubiquitously expressed enzyme that catalyzes the final reaction in the major pathways of triglyceride synthesis. Mice lacking DGAT1 (Dgat–/–) demonstrate significant changes in lipid metabolism in several tissues, including the skin. Here we report the effects of DGAT1 deficiency on fur and sebaceous glands. Adult Dgat–/– mice had dry fur and hair loss, which were associated with atrophic sebaceous glands and fur lipid abnormalities. As a result, Dgat–/– mice had impaired water repulsion and defective thermoregulation after water immersion. These phenotypes were mostly absent in Dgat–/– mice with leptin deficiency, indicating an unexpected role for leptin in modulating the skin phenotype. Our findings indicate that DGAT1 plays an important role in normal fur and sebaceous gland physiology and provide evidence that leptin modulates these processes in the skin.
Ebstein's anomaly in a woman athlete
Authors: A. H. Douglas
Journal: JAMA (1972)

A 20-year-old woman with Ebstein's anomaly was participating in competitive athletics at college. An electrocardiogram would have provided an obvious clue to the existence of cardiac disease, had it been taken. A plea is made for routine electrocardiography as part of the standard examination of all candidates for competitive athletics, regardless of age.
A REMEDY FOR PROFESSIONAL UNREST
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Graduate medical education in the United States
Authors: B. D. Rowley
Journal: JAMA (1990)

This annual report on graduate medical education in the United States for the 1989-1990 academic year contains data on the number of programs accredited by the Accreditation Council for Graduate Medical Education (ACGME), by specialty and by region, and provides information on some characteristics of the programs and the persons in these programs. This year for the first time data on graduate medical education were gathered by means of an electronic data collection system. This major change in the data collection system resulted in a response rate lower than that in recent years. While actual response figures are reported herein, many tables include an extra column that provides a statistical projection for the expected number of residents. In view of the lower response rate, the reader is advised to interpret the data in this report with caution. In 1989, the ACGME began to accredit, through the Residency Review Committees, programs
Postexercise proteinuria in humans. Facts and mechanisms
Authors: J. R. Poortmans
Journal: JAMA (1985)

Strenuous exercise induces profound changes in renal hemodynamics and the protein content of urine. Postexercise proteinuria seems to be directly related to the intensity of exercise, rather than to its duration. The pattern of proteins identified in urine collected after exercise is different from normal physiological proteinuria. Immunochemical techniques demonstrate that postexercise proteinuria is of mixed glomerular-tubular type when heavy exercise is involved. The origin of proteinuria after light exercise seems to be preponderantly of glomerular type. Clearance of individual plasma proteins suggests an increased glomerular permeability and a partial tubular-reabsorption inhibition of macromolecules. (<i>JAMA</i>1985;253:236-240)
The Board of Trustees
Journal: JAMA (1985)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
'Nobody Speaks For the Fetus'
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Second Annual Clinical Hyperthermia Symposium and Workshop
Journal: JNCI Journal of the National Cancer Institute (1986)

Journal Article Second Annual Clinical Hyperthermia Symposium and Workshop Get access JNCI: Journal of the National Cancer Institute, Volume 76, Issue 6, June 1986, Page 1339, https://doi.org/10.1093/jnci/76.6.1339-f Published: 01 June 1986
Credibility of Scientists: Barrow and Conrad Respond
Authors: Craig S. Barrow, James W. Conrad
Journal: Environmental Health Perspectives (2006)

Uncertainty" (Schmidt 2005) overlooked many serious concerns about the environmental and health risks of this new technology.Potential problems from antibiotic-resistant genes used in gene-altered crops, risks from unintended effects of the genetic engineering process, the increases in pesticide use stemming from widespread planting of genespliced varieties-these and several other concerns were ignored or hardly mentioned in the lengthy article.Additional information on this topic is available from the Center for Food Safety (CFS 2000(CFS , 2004)).Instead, Schmidt's article states that "GM agriculture is here to stay" (Schmidt 2005) and gives readers the false impression that safety and regulatory issues have been adequately addressed by industry and government.Nothing could be further from the truth.For example, regarding the risk of allergies from gene-altered foods, Schmidt stated that biotech companies avoid allergy problems by avoiding genes from the most common allergens.However, in an editorial in the New England Journal of Medicine, Nestle (1996) pointed out that this approach leaves many uncertainties:Most biotechnology companies use microorganisms rather than food plants as gene donors, even though the allergenic potential of these newly introduced microbial proteins is uncertain, unpredictable, and untestable ….Because FDA requirements do not apply to foods that are rarely allergenic or to donor organisms of unknown allergenicity, the policy would appear to favor industry over consumer protection.
New Self-help Videos
Journal: JAMA (1996)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Front &amp; Back Matter
Authors: Marloes M. Gerrits, Patricia van Oppen, Harm W. van Marwijk, Henriëtte van der Horst, Brenda W. Penninx, John S. Ogrodniczuk, Anthony S. Joyce, William E. Piper, Louisa G. Sylvia, Amy T. Peters, Thilo Deckersbach, Andrew A. Nierenberg, Giovanni A. Fava, Sarah E. Romans, David Kreindler, Eriola Asllani, Gillian Einstein, Sheila Laredo, Anthony Levitt, Kathryn Morgan, Michele Petrovic, Brenda Toner, Donna E. Stewart, Søren Dinesen Østergaard, Georgios Petrides, Peter Thisted Dinesen, Søren Skadhede, Per Bech, Povl Munk-Jørgensen, Jimmi Nielsen, Fiammetta Cosci, Giovanni A. Fava, Jenny Rosendahl, Katharina Tigges-Limmer, Jan Gummert, Ralf Dziewas, Johannes Maximilian Albes, Bernhard Strauss, Satz Mengensatzproduktion, Druck Reinhardt Druck Basel, Druck Reinhardt Druck Basel
Journal: Psychotherapy and Psychosomatics (2012)
I'm hoping to finish my reg year in August 2007 and I'm stuck, not knowing where and when I should be looking for jobs. I'm hoping to get a job in London or the south east of England but I've heard it is next to impossible to get anything as there are no partnerships and the locum/salaried job market is completely saturated. If I pass MRCGP what do you think I should do?
Authors: Rodger Charlton
Journal: BMJ (2007)

Have a career related problem that needs answering? Can9t find the person to point you in the right direction? Log on to the Advice Zone for reliable medical careers advice. You can post a question or see if one of our 300 advisers has already answered a similar question. Here is a selection of questions and answers posted on the site <b>www.bmjcareers.com/advicezone</b>
Creeping Eruption
Authors: Thomas H. Cates
Journal: JAMA (1913)

<h3>To the Editor:</h3> —I have noted the publication of reports of two cases of creeping eruption (The Journal, July 26, 1913, p. 247), by Dr. Gustave L. Rudell, in one of which, in August, 1912, he was able to recover the larva. In view of the fact, as stated therein, that recovery of the parasite producing this lesion is exceedingly rare, only two investigators having previously reported finding it, it might be of interest to report that in August, 1910, I succeeded in recovering two of these organisms from such a case while in hospital work in Philadelphia. I had not reported the case prior to this writing, since that part of the limited literature on the subject which had come under my observation had not before impressed me with the fact that the demonstration of this organism in connection with these cases was of such rare occurrence as
Phenylpropanolamine
Authors: H. I Silverman
Journal: JAMA (1982)

<h3>To the Editor.—</h3> The editorial entitled "Phenylpropanolamine: An Over-the-Counter Amphetamine?" (1981; 245:1346) by Alan Blum, MD, emphasizes perceived problems with overthe-counter (OTC) medication yet disregards scientific evidence that helps assure the American public of both safety and effectiveness of consumer medication. The public advisory committees of the Food and Drug Administration are composed of highly qualified persons from specialized fields with wide geographic distribution. Chastising or indirectly criticizing the recommendations of FDA advisory panels without an apparent awareness of the facts and scientific data on which recommendations were made is unfortunate. To imply that phenylpropanolamine is an OTC amphetamine is not in keeping with the weight of evidence to the contrary. Although Dietz (1981; 245:601) implies an "amphetaminelike" reaction in patients using phenylpropanolamine, the neurological effects he collated provide no mention of mood elevation, euphoria, increased energy, or alertness, all of which are associated with the pattern of amphetamine abuse.
Conflicts of interest in the publication of science
Authors: D. Rennie
Journal: JAMA (1991)

Allegations that greed and conflicts of interest are eroding the integrity of the scientific community<sup>1</sup>—a community funded with billions of federal dollars—have led the government to turn a vigilant eye toward the uses and potential abuses of scientific research. In response to such scrutiny, the US Public Health Service proposed guidelines to prevent conflicts of interest from interfering with federally funded research. The guidelines required all investigators involved in research funded by the National Institutes of Health—as well as their spouses and dependent children—to disclose "all financial interests and outside professional activities."<sup>2</sup>After facing "a firestorm of protest,"<sup>3</sup>the Public Health Service scrapped the guidelines, though it still hopes to develop new ones that do not disturb the research community so violently. This reaction was best expressed by Hittelman,<sup>4</sup>who criticized the "insidious assumption that seems to underlie the guidelines: that the university biomedical research