tbuckley/cabot-search huggingface dataset:
Serum Levels of Potassium Penicillin V in Febrile and Afebrile Children
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
High Prevalence of Chlamydial and Gonococcal Infection in Women Entering Jails and Juvenile Detention Centers— Chicago, Birmingham, and San Francisco, 1998
Journal: JAMA (1999)

The prevalence of sexually transmitted diseases (STDs) is high among women entering corrections facilities. Screening for STDs in these facilities, however, is difficult because of the large number of persons admitted each day and the frequent shortage of medical staff and examination space. New, sensitive urine tests for gonorrhea and chlamydia have made screening practical outside of medical settings. To assess the feasibility of screening women in corrections facilities for chlamydial and gonococcal infection using urine tests and to determine the prevalences of these infections, the Chicago Department of Public Health and the University of Alabama at Birmingham (UAB) began testing women and adolescent females entering the Cook County Jail and the Cook County Juvenile Temporary Detention Center in Chicago and the Jefferson County Jail and the Jefferson County Youth Detention Center in Birmingham, respectively, in 1998. The San Francisco Department of Public Health has been testing women at the San Francisco County jails for chlamydial and gonococcal infections using urine tests since 1996 and adolescent females at the San Francisco Youth Guidance Center since 1997. This report summarizes the findings for testing incarcerated women in 1998 in the three cities; preliminary results indicate that, in these facilities, testing for chlamydial and gonococcal infections is feasible and that a high percentage of women test positive for these infections.
Improved diagnosis of unilateral renal artery lesions after captopril administration
Authors: M. Thibonnier
Journal: JAMA (1984)

Captopril was administered (1 mg/kg of body weight) to 37 unselected hypertensive patients undergoing bilateral renal vein catheterization to determine its safety and efficacy in diagnosing hypertension related to unilateral renal artery lesions. In the 18 patients who had a unilateral renal artery lesion demonstrated by angiography, the ratio of plasma renin activity of the involved to uninvolved renal vein rose significantly after administration of captopril, whether or not patients were taking antihypertensive medication. This postcaptopril ratio differentiated cases of unilateral lesions from cases of bilateral lesions or absence of lesions without any overlap. The test was well tolerated despite occasional large drops in blood pressure. These data show that converting enzyme inhibition increases the diagnostic accuracy of renal vein catheterization by increasing the difference between the amount of plasma renin secreted by the two kidneys in cases of unilateral renal artery lesions. (<i>JAMA</i>1984;251:56-60)
An Overview of Peroxisome Proliferator-Induced Hepatocarcinogenesis
Authors: M. Sambasiva Rao, Janardan K. Reddy
Journal: Environmental Health Perspectives (1991)

Peroxisome proliferators are hepatocarcinogens in rats and mice. Chronic administration of these compounds results in the development of altered areas and neoplastic nodules followed by hepatocellular carcinomas. All three types of hepatic lesions do not express gamma-glutamyltranspeptidase, glutathione 8-transferase-P, and alpha-fetoprotein and are resistant to iron accumulation after overload. The mechanism by which nongenotoxic peroxisome proliferators induce hepatic tumors is not well understood. It has been proposed that with continuous administration of peroxisome proliferators, liver cells are subjected to persistent oxidative stress resulting from marked proliferation of peroxisomes and a differential increase in the levels of H2O2 producing (20- to 30-fold) and degrading (2-fold) enzymes. Free oxygen radicals lead to DNA damage (both directly and through lipid peroxidation) and thus may cause initiation and promotion of the carcinogenic process.
PTU-129 Anal Evoked Potentials at ‘Twitch’ Threshold: a New Method for Exploration of Anal Sensory Function
Authors: E V Carrington, E Horrocks, S Connolly, M Scott, C Knowles
Journal: Gut (2013)

<h3>Introduction</h3> Faecal incontinence can be associated with impaired anal sensitivity. Anal evoked potentials (EPs) have previously been used to quantify anal sensory function; however the traditional technique of stimulating at a percentage of pain threshold may result in poorly reproducible results with significant inter-individual variability. The aim of this study was to develop a reliable and reproducible method of recording anal EPs, and to define waveform characteristics in healthy volunteers. <h3>Methods</h3> Twenty eight healthy volunteers (21 F, median age 34 [range 21–74]) without bowel dysfunction were recruited for the study. Anal EPs were recorded in response to stimulation (using a bipolar electrode) 1cm from the anal verge. In contrast to previous studies, stimulation intensity was delivered at motor threshold (determined by visualisation of an anal ‘twitch’). Four sets of 50 stimuli (0.2 Hz frequency, 0.2 ms pulse duration) were given with 5-minute intervals between sets to reduce habituation. A repeat study was performed in 7 volunteers after a minimum interval of 2 weeks. Recordings were taken between channels Cz-A1 and Cz’-Fz (International 10–20 system) in accordance with previously published literature. Runs were averaged and latencies for EP responses were defined, analysed and compared. <h3>Results</h3> Motor threshold stimulation (median 20, range 10–36 mA) was well tolerated in all volunteers and resulted in reproducible polyphasic waveforms. The first negative peak (N1) was clearly identifiable on all traces. In the Cz’-Fz channel, the latency to N1 was 130 ± 20 ms (coefficient of variation [COV] = 15%). This was less variable than N1 in Cz-A1 (153 ± 34 ms; COV = 22%) and much less than published previously (COV of N1 = 39%; Remes-Troche <i>et al. Neurogastroenterol Motil</i> 2011). Analysis of repeat studies demonstrated that latencies in channel Cz’-Fz were the most reproducible (ICC of N1 latency = 0.95 [very strong agreement]). <h3>Conclusion</h3> Electrical stimulation at motor threshold and recording of evoked potentials from channel Cz’-Fz is a reliable and reproducible method for examination of anal sensory function. Latency to N1 is the most consistent waveform component and is highly reproducible. The technique of stimulation at ‘twitch’ threshold appears to reduce inter-subject variability and may allow application to further explore both the pathophysiology of anal dysfunction and the effect of treatments aimed at modulating anal neuronal function. <h3>Disclosure of Interest</h3> None Declared <h3>Reference</h3> Remes-Troche JM, Tantiphlachiva K, Attaluri A,<i> et al</i><i>.</i> A bi-directional assessment of the human brain-anorectal axis. <i>Neurogastroenterol Motil</i><i></i> 2011; <b>23</b>: 240–248, e117–248
VITAL STATISTICS OF THE ELEVENTH CENSUS.
Journal: JAMA (1898)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Masthead: (Adv. Healthcare Mater. 11/2019)
Journal: Advanced Healthcare Materials (2019)

Citizenship: Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have focused on sharing our content with those in need, enhancing community philanthropy, reducing our carbon impact, creating global guidelines and best practices for paper use, establishing a vendor code of ethics, and engaging our colleagues and other stakeholders in our efforts.
Ueber in fluenzapsychosen. Von Dr. Richard Jutrosinskl in Strassburg. Sonderabdruck aus derDeutschen Medicinischen Wochenschrift, 1891, No. 3. [The Psychoses of Influenza. By Dr. Richard Jutrosinski, of Strasburg. Reprint from theDeutsche Med. Wochenschrift, 1891, No. 3.]
Journal: American Journal of Psychiatry (1892)
Medico-Legal Law Brief in Relation to Malpractice Suits with Citations
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Electrocardiographic changes during human anaphylaxis
Authors: B. H. Booth
Journal: JAMA (1970)

Twenty-three instances of anaphylaxis in humans were observed. Electrocardiograms were obtained within 24 hours of the acute episode in 14 of the 23 patients. Six patients had abnormal ECGs. The abnormal findings were variable and consisted of flattening of the T waves, inversion of the T waves, ST segment elevation or depression, a nodal rhythm, and atrial fibrillation. The electrocardiographic changes are considered to be specifically related to the anaphylaxis for several reasons. In at least three of the patients, agents used for treatment of the anaphylaxis could not be implicated. No evidence of preexisting heart disease was apparent in any patient. The electrocardiographic changes appear to parallel similar changes that occur during experimentally induced anaphylaxis in subhuman primates. The exact mechanism responsible for production of the electrocardiographic changes is unknown. Multiple factors could be involved.
Contribution to Pathogenesis of Renal Anemia
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Leads from the MMWR. Violent deaths among persons 15 to 24 years of age--United States
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
PROGRAM IN MEDICAL JOURNALISM
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Office Based Oral Desensitization of Patients With Anaphylactic Sensitivity to Foods Is Safe and Effective
Authors: R.L. Wasserman, L.E. Mansfield, A.R. Gallucci, H.R. Hutteman, A.M. Ruvalcaba, N.A. Long, D.M. Pence
Journal: Journal of Allergy and Clinical Immunology (2010)
Corrections
Authors: Christophe Hézode, Françoise Roudot‐Thoraval, Son Nguyen, Pascale Grenard, Boris Julien, Elie‐Serge Zafrani, Jean‐Michel Pawlotsky, Daniel Dhumeaux, Sophie Lotersztajn, Ariane Mallat
Journal: Hepatology (2005)

In the article entitled “Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C” by Hézode et al. (HEPATOLOGY 2005:42:63–71), Dr. Pawlotsky's name was misspelled in the author byline. The correct byline should read as follows: Christophe Hézode, Françoise Roudot-Thoraval, Son Nguyen, Pascale Grenard, Boris Julien, Elie-Serge Zafrani, Jean-Michel Pawlotsky, Daniel Dhumeaux, Sophie Lotersztajn, and Ariane Mallat
Announcement: World Hepatitis Day — June 28, 2017
Journal: MMWR Morbidity and Mortality Weekly Report (2017)

CDC monitors progress on selected national human immunodeficiency virus (HIV) prevention and care objectives using surveillance data (1) and has released two HIV care continuums for 2014: a diagnosis-based continuum and a prevalence-based continuum (2,3).A diagnosis-based HIV continuum monitors key steps needed for a person living with diagnosed HIV infection to reach viral suppression, which leads to improved health outcomes and reduced risk for transmission to others.To determine a diagnosisbased HIV continuum, CDC uses the number of persons living with diagnosed HIV infection as the denominator.CDC monitors engagement in medical care and viral suppression in 38 jurisdictions that have complete reporting of CD4 and viral load laboratory results.Among persons living with diagnosed HIV infection at year-end 2014 in 38 jurisdictions, 73% received HIV medical care in 2014, 57% were retained in continuous care, and 58% were virally suppressed (1).Because the first step in entering HIV care is receiving a diagnosis, CDC has also estimated an HIV prevalence-based continuum, which uses the estimated number of all persons living with diagnosed or undiagnosed HIV infection as the denominator.Among the estimated 1.1 million persons living with HIV infection in the United States in 2014, 85% had received a diagnosis (1).Extrapolating from 38 jurisdictions with complete reporting, an estimated 62% of persons living with HIV infection received HIV medical care in 2014, 48% were retained in continuous care, and 49% were virally suppressed (2).More information is available in the Division of HIV/AIDS Prevention report and accompanying fact sheet and slide set (1-3).
Celestin tubes
Authors: J. Bristol
Journal: BMJ (1979)

<h3>Abstract</h3> The activation of Wnt/β-catenin (cWnt) signaling at the future posterior end of early embryos is a highly conserved mechanism for initiating pattern formation along the anterior-posterior (AP) axis in bilaterians. Moreover, in many bilaterian taxa, in addition, to activation of cWnt signaling at the posterior end, inhibition of cWnt signaling at the anterior end is required for normal development of anterior structures. In most cases, inhibition of cWnt signaling at the anterior end occurs around gastrulation and it is typically mediated by secreted factors that block signal transduction through the cWnt cell surface receptor-ligand complex. This phenomenon has been fairly well characterized, but the emerging role for intracellular inhibition of cWnt signaling in future anterior blastomeres—in cleavage stage embryos—to regulate correct AP patterning is less well understood. To investigate this process in an invertebrate deuterostome embryo we studied the function of Axin, a critical negative regulator of cWnt signaling, during early sea urchin embryogenesis. Sea urchin <i>Axin</i> is ubiquitously expressed in early embryos and by the blastula stage the expression of the gene becomes restricted to the posterior end of the embryo. Strikingly, knockdown of Axin protein levels using antisense Axin morpholinos (MO) led to ectopic nuclearization of β-catenin and activation of endomesoderm gene expression in anterior blastomeres in early embryos. These embryos developed a severely posteriorized phenotype that could be fully rescued by co-injection of Axin MO with wild-type Axin mRNA. Axin is known to negatively regulate cWnt by its role in mediating β-catenin stability within the destruction complex. Consistent with this function overexpression of Axin by mRNA injection led to the downregulation of nuclear β-catenin, inhibition of endomesoderm specification and a strong anteriorization of embryos. Axin has several well-defined domains that regulate its interaction with β-catenin and the key regulators of the destruction complex, Adenomatous Polyposis Coli (APC), Glycogen Synthase Kinase 3β(GSK-3β), and Dishevelled (Dvl). Using Axin constructs with single deletions of the binding sites for these proteins we showed that only the GSK-3βbinding site on Axin is required for its inhibition of cWnt in the sea urchin embryo. Strikingly, overexpression of the GSK-3β-binding domain alone led to embryos with elevated levels of endomesoderm gene expression and a strongly posteriorized phenotype. These results indicated that Axin has a critical global role in inhibiting cWnt signaling in the early sea urchin embryo, and moreover, that the interaction of Axin with GSK-3βis critical for this inhibition. These results also add to the growing body of evidence that Axin plays a global function in suppressing cWnt signaling in early embryos and indicates that modulation of Axin function may be a critical early step during patterning of the AP axis during bilaterian development
Massachusetts Medical Society
Authors: Katherine A. Leland, Harry D. Wilson, Ralph D. Brackett, Joshua J. Hurwitz, J. Joseph Freedman, J. Stanley Carp, Mark L. Purinton, Carl W. Janovsky, Paul F. Kelly, Salvatore N. Mangano, Gertrude E. Murray, M. Donna Younger, Donald A. Martin, Edward A. Pollard, Charles Averill, Charles I. Brink, Norman W. Beberman
Journal: New England Journal of Medicine (1974)

APPLICANTS FOR FELLOWSHIPPublished in Accordance with the Provisions of Chapter II, Section 2.301, of the BylawsBarnstableBete, John Morris, Cape Cod Medical Center, Hyannis 02601. Boston University School of Medicine, 1965.Chabra, Roger Nathan, 40 Lewis Bay Road, Hyannis 02601. Christian Medical College, Punjab University, Ludhiana, India.Gadkowski, Walter Joseph, 66 Lewis Bay Road, Hyannis 02601. Jefferson Medical College of Philadelphia, 1969.Vandemoer, John Nicholas, Yellow Brick Road, Hyannis 02601. Tulane University School of Medicine, 1969.BerkshireAustin, Frederick Lowell, JR., 127 North Street, Pittsfield 01201. Tufts University School of Medicine, 1958.Becker, Daniel Ira, North Adams Regional . . .