tbuckley/cabot-search huggingface dataset:
JAMA
Authors: Thomas Easley, Brian Shields, Karen Adams-Taylor, Paul Gee, Monica Smith, Karl Elvin, Nancy Essex, Jaye Mize, Sean O'donnell, Sue Sherrill, Sara Zimmerman Managers, David Antos, Anthony Bautista, Chris Borden, Debra Camp, Jennifer Carney, Lydia Cruz, Scott Curl, Diane Darnell, Jordynn Farrar, Allison Hughes, Colleen Kelly, Chris Meyer, Annemarie Neff, J Neff, Sean Ohlson, Phil O'leary, Bill Pedone, Susan Price, Binita Shah, Erin Spencer, Denise Steinhauser, Joe Advertising, Production Services, Ahmed Avendano, Kim Boler, Rhonda Brown, Mike Deegan, Daniel Degroot, Euwanaha Joiner-Smith, Joshua Lane, Cindy Rendlen, Ellen Yoshihara, Circulation Services, Julie Burton, Ronna Hewitt, Mary Sieck, Geneine Someren, Jamaal Vargas, New Media, Gail Barrett, Regina Brownlee, Amanda Camino, Brenda Chandler-Grayer, Emily Dunn, Amy Evers, Maleeka Holden, Teri Hutchison, Joshua Lampinen, Nathan Mitre, Patricia Panek, Marla Seidell, La Son, Diggs Sledge, Julian Graphics, Joe Amft, James Collver, Maria Duda, Fred Furtner, Carolyn Hall, Maria Kowalkowski, Carla Benton, Carol Farrell, Daniel James, Judith Literskis, Teresa Omiotek, Michael Ryder, Jeff Ery, J Bonistalli Manager, Kathy Russell, Mirna Monal, Maureen Reichert, Nancy Souza, Christine Hearne, Natasha Nekola, David Baum, Morgan Osgood, Ron Thomas, Elizabeth Solaro, Lindsay Dawson, Ellen Gibson, Fergus Clare, Peter Litton, Regina Nisengolts, Jon Perkins, Daniel Pickhardt, Romando Rossini, Sarah Subramanian, Stacy Tucker, Mustafa Ishaq, Craig Mccaff, Sirisha Alluri, James Madara, Bernard Hengesbaugh, Barbara Mcaneny, Patrice Harris, David Barbe, Russell Kridel, Susan Bailey, Bruce Scott, Willarda Edwards, Jesse Ehrenfeld, Sandra Ferguson, Gerald Fryhofer, William Harmon, William Kobler, Mario Mcdade, ; Motta, Albert Mukkamala, Jack Osbahr, Ryan Resneck, Karthik Ribeira, Georgia Sarma, Kevin Tuttle
Journal: JAMA (2018)
Charlson Comorbidity Index (CCI) Not Hematopoietic Cell Transplantation Specific-Comorbidity Index (HCT-CI) Successfully Predicts Transplant Related Mortality and Post-Transplant Outcomes in Elderly Patients Undergoing Reduced Intensity Conditioning (RIC) Umbilical Cord Blood (UCB) Transplantation
Authors: Tamila L. Kindwall-Keller, Mary J. Laughlin, Pingfu Fu, Hillard M. Lazarus, Paolo F. Caimi, Cynthia Owusu, Merle J. Kolk, Richard J. Creger, Huda S. Salman, Stanton L. Gerson, Kenneth R. Cooke, Brenda W. Cooper
Journal: Blood (2011)
Neuro-ophthalmology
Authors: Henry J. L. Van Dyk
Journal: JAMA (1969)

For one who has not attended the annual Neuro-ophthalmologyfest in Miami, reading this book will be like listening to "Swan Lake" on the radio: the music is there, but one misses all the action. The chief choreographer, Dr. J. Lawton Smith, has apparently attempted to make up for this loss by adding a large number of scenes not present in the original Miami production. Two of these additions, Newton's beautifully illustrated piece on the posterior fossa cisterns and Tyler's contribution on the psychophysiology of vision, are almost worth the price of the book by themselves. In general the material is notably good. The English neurologist, Meadows, has contributed two excellent studies, on a series of 80 cases of temporal arteritis, and also on atypical modes of presentation of pituitary adenoma. Taveras also contributes twice, on low pressure hydrocephalus and on temporal lobe tumors. Walker and Walsh have a fine paper
Weight-Training Exercises To Counteract the Negative Effects of Low-Protein Diets in People with Kidney Disease
Journal: Annals of Internal Medicine (2001)

Summaries for Patients4 December 2001Weight-Training Exercises To Counteract the Negative Effects of Low-Protein Diets in People with Kidney DiseaseSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-11-200112040-00003 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?Doctors often recommend low-protein diets for people with kidney disease because such a diet delays the worsening of kidney disease. However, patients who don't eat protein lose muscle. When patients lose enough muscle, they become weak and less able to carry out their usual activities. Lifting weights (resistance training) builds up muscle and reduces loss of muscle in such diseases as HIV infection and congestive heart failure. No one has tested resistance training to see if it prevents loss of muscle in patients with kidney disease who are ... Author, Article, and Disclosure InformationThe summary below is from the full report titled “Resistance Training To Counteract the Catabolism of a Low-Protein Diet in Patients with Chronic Renal Insufficiency.” It is in the 4 December 2001 issue of Annals of Internal Medicine (volume 135, pages 965-976). The authors are C Castaneda, PL Gordon, KL Uhlin, AS Levey, JJ Kehayias, JT Dwyer, RA Fielding, R Roubenoff, and MF Singh.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoResistance Training To Counteract the Catabolism of a Low-Protein Diet in Patients with Chronic Renal Insufficiency Carmen Castaneda , Patricia L. Gordon , Katherine Leigh Uhlin , Andrew S. Levey , Joseph J. Kehayias , Johanna T. Dwyer , Roger A. Fielding , Ronenn Roubenoff , and Maria Fiatarone Singh Metrics 4 December 2001Volume 135, Issue 11Page: I-60KeywordsCatabolismDietExerciseHIV infectionsHeart diseasesHeart failureMuscle proteinsMusclesRenal diseases ePublished: 4 December 2001 Issue Published: 4 December 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Losing my licence meant I lost my independence
Journal: BMJ (2020)

In light of evidence presented by the author to the Secretary of State's Medical Advisory Panel at the DVLA, the DVLA now considers eclampsia an exception in the provoked seizures category (, under the tab "show all updates").This means women in the UK do not need to inform the DVLA or surrender their driving licences for six months following a confirmed diagnosis of eclampsia.
Gonorrheal Proctitis
Authors: Zachary M. Kilpatrick
Journal: New England Journal of Medicine (1972)

DESPITE widening concern over increasing cases of gonorrhea, primary attention remains focused on the genital orifices. It is worth pointing out that some patients thought to have ulcerative proctitis in fact have gonococcal proctitis, which can be readily treated.Methods of InfectionStratified squamous epithelium resists invasion by the gonococcus, but surfaces covered with columnar and transitional epithelium are more easily penetrated.1 The most obvious route of inoculation is direct implantation by rectal intercourse, but in women, the infectious vaginal discharge from genital gonorrhea may soil the anorectal mucosa everted during defecation.2 Indeed, when it is looked for by direct . . .
PWE-055 The prevalence, clinical relevance and impact on diet of lactose intolerance in a population with lactase deficiency: a randomised, double-blind, dose response study in healthy subjects and patients with diarrhoea predominant irritable bowel syndrome
Authors: M R Fox, J Yang, Y Deng, Y Cong, M Fried, N Dai
Journal: Gut (2012)

<h3>Introduction</h3> Lactose Intolerance (LI) is a common clinical syndrome; however there is a lack of high quality evidence about its epidemiology, diagnosis and clinical relevance in health and patients with functional gastrointestinal disease. Additionally the impact of LI on intake of dairy produce is uncertain because previous studies have often tested tolerance only at very high doses and/or failed to assess both self perceived and objective lactose tolerance. <h3>Aim</h3> To assess the prevalence of LI in a population with lactose malabsorption and the effect of LI on intake of dairy products in healthy volunteers (HVs) and patients with diarrhoea predominant irritable bowel syndrome (D-IBS). <h3>Methods</h3> A Chinese population known to have a high prevalence of lactase deficiency was studied. 60 D-IBS patients and 60 HVs underwent hydrogen breath test (HBT) at 10 g, 20 g, 40 g lactose on three test days in a randomised, double-blind three way cross-over study. Lactose Malabsorption (LM; H2 rise &gt;20 ppm) and intolerance (LI ≥2 point rise on validated symptom score) were assessed at each dose. Genetic sequencing of the lactase gene promoter region was also performed. The impact of LI (both self-reported and from HBT) on lactose intake was assessed by dietary questionnaire. <h3>Results</h3> LM was prevalent in HVs and D-IBS patients (93% vs 92% at 40 g lactose, p=0.73). LI prevalence was lower in HVs than D-IBS patients at 10 g (3% vs 18%, OR 6.51 (CI 1.38 to 30.8), p=0.008), 20 g (22% vs 47%, OR 3.16 (CI 1.43 to 7.02), p=0.004) and 40 g (68% vs 85%, OR 2.63 (CI 1.08 to 6.42), p=0.03). The genotype in all participants was C/C-13 910 and no other SNP was identified on gene sequencing of the lactase gene regulatory sequence. Most participants (83/120 (69%)) included milk and dairy products in their diet; however D-IBS patients reported less frequent intake of dairy products than HVs and a smaller amount of lactose in the diet (D-IBS: 9.0 g (4.5–17.3) vs HVs: 19.5 g (6.0–36.4); p=0.040). D-IBS patients also self-reported LI more frequently than HVs (63% vs 22%, OR 6.25 (CI 2.78 to 14.0), p&lt;0.001); however, self-reports of LI did not predict results of objective HBT. <h3>Conclusion</h3> The likelihood of LI is increased in patients with D-IBS, especially at low lactose doses. Self reported lactose intolerance, but not objective LI on HBT, was associated with avoidance of dairy products. <h3>Competing interests</h3> M Fox Grant/Research Support from: Nestle International, J Yang: None declared, Y Deng: None declared, Y Cong: None declared, M Fried: None declared, N Dai: None declared.
Memoirs of a Small-Town Surgeon
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Posaconazole or Fluconazole for Prophylaxis in Severe Graft-versus-Host Disease
Authors: Susan Wolf, Sharon Moalem
Journal: New England Journal of Medicine (2007)

table documenting how often each type of bioethics evidence or testimony has been offered, whether the court allowed it, and how it was used.Bioethics in Law offers a treasure trove of information that cannot readily be found elsewhere, shedding light on the complex interaction between bioethics and law.Spielman's pathbreaking research and thoughtful organization of the issues provide an important resource for those concerned about the confusion over the roles of bioethics and law.After all, as Spielman suggests, we should not want judges to defer to bioethicists to determine our legal rights, but neither should we want judges determining our rights as patients, research subjects, or health professionals by ignoring the insights that bioethics can offer.
Munchausen Syndrome
Authors: F. Tuchler
Journal: BMJ (1955)

Several algorithms exist to facilitate spirometric interpretation in clinical practice, yet there is a lack of consensus on how spirometric criteria for asthma, COPD, and restrictive disorders should be incorporated into spirometry interpretation algorithms suitable for use in day-to-day primary care management. The purpose of this review was to identify and describe the variability that exists among spirometry interpretation algorithms and how this might be relevant to the interpretation of spirometric data of common conditions encountered in primary care. MEDLINE, Embase, and mainstream search engines were used to identify all English-language spirometry interpretation algorithm–related material between January 1990 and December 2018. Eight variations in spirometry interpretation algorithms were identified via specific&nbsp;a priori assumptions that each spirometry interpretation algorithm should contain content consistent with national and international guidelines related to spirometry interpretation. Of the 26 spirometry interpretation algorithms identified, 5 were deemed impractical for day-to-day use in primary care (19%), 23 lacked a logic string leading to the postbronchodilator FEV<sub>1</sub>/FVC (88%), 4 relied on postbronchodilator change in FEV<sub>1</sub> to distinguish between asthma and COPD (15%), 24 lacked a prompt for bronchodilator challenge when FEV<sub>1</sub>/FVC was considered to be at a normal level (92%), 12 did not indicate whether the data represented a prebronchodilator or postbronchodilator scenario (46%), 7 did not include a logic string that considers mixed obstructive/restrictive defect (27%), 23 did not contain a prompt to refer for methacholine challenge testing when spirometry appeared normal (88%), and 2 spirometry interpretation algorithms did not include a logic string leading to restrictive disorder (8%). Our review suggests that there is considerable variability among spirometry interpretation algorithms available as diagnostic aids and that there is a need for standardization of spirometry interpretation algorithms in primary care.
Council on Medical Education and Hospitals
Journal: JAMA (1962)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
What the educators are saying
Authors: Ed Peile, Peter Ferry, Lara McCarthy
Journal: BMJ (2004)

Universities are increasingly offering medical teachers training in teaching skills, but where is the evidence that this makes a difference? A controlled study looked at the training offered to teachers by 22 universities in eight countries and found that the trained teachers became more student focused in their approaches to teaching (while the control group became more teacher focused as they progressed in teaching)—and that students' scorings across five different teaching skills also improved. Most importantly, the training of teachers led to positive changes in their students' learning patterns, reducing the extent to which students adopt surface approaches to learning, in favour of more effective approaches. Interesting evidence for clinical managers who begrudge time off to learn how to teach. Active Learning in Higher Education2004;5: 87–100 [OpenUrl][1][Abstract][2] Two Californian medical students and a psychologist have collected a series of 22 personal statements or essays about medical student life, which make compulsive reading for medical teachers. Although there is a very “west coast of America” feel … [1]: {openurl}?query=rft.jtitle%253DActive%2BLearning%2Bin%2BHigher%2BEducation%26rft.stitle%253DActive%2BLearning%2Bin%2BHigher%2BEducation%26rft.issn%253D1469-7874%26rft.aulast%253DGibbs%26rft.auinit1%253DG.%26rft.volume%253D5%26rft.issue%253D1%26rft.spage%253D87%26rft.epage%253D100%26rft.atitle%253DThe%2BImpact%2BOf%2BTraining%2BOf%2BUniversity%2BTeachers%2Bon%2Btheir%2BTeaching%2BSkills%252C%2Btheir%2B%2B%2B%2B%2B%2B%2B%2BApproach%2Bto%2BTeaching%2Band%2Bthe%2BApproach%2Bto%2BLearning%2Bof%2Btheir%2BStudents%26rft_id%253Dinfo%253Adoi%252F10.1177%252F1469787404040463%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=spalh&resid=5/1/87&atom=%2Fbmj%2F329%2F7466%2F610.atom
Highlights
Authors: Howard Bauchner
Journal: JAMA (2018)

Laryngeal Tube Insertion for Cardiopulmonary Resuscitation 769During resuscitation with endotracheal intubation, the endotracheal tube may be malpositioned or dislodged.Wang and colleagues randomized 3004 adults with out-of-hospital cardiac arrest who were resuscitated by paramedics from 27 emergency medical services agencies and found that a strategy of laryngeal tube insertion was associated with significantly greater 72-hour survival compared with a strategy of endotracheal intubation.In an Editorial on 2 trials of advanced airway management, Andersen and Granfeldt speculate whether an even simpler technique, bag-valve-mask ventilation, would have similar or better outcomes.
High plasma insulin level a prime risk factor for heart disease
Journal: JAMA (1979)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Update: Perinatally Acquired HIV/AIDS—United States, 1997
Journal: JAMA (1997)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract P203: Building Cardiovascular Risk Prediction Models by Applying Machine Learning Methods to Right-Censored Electronic Health Data
Authors: Ales Kotalik, David Vock, Julian Wolfson, Patrick O’Connor
Journal: Circulation (2017)

Background: Cardiovascular (CV) risk prediction is useful in prioritizing resources and guiding treatment decisions. Most risk prediction equations are constructed using data from cohort studies. However, these cohorts often suffer from lack of diversity or generalizability. Therefore, there is an increasing interest in using electronic health data (EHD) to construct CV risk models. Given the size and complexity of EHD, machine learning (ML) techniques are an appealing alternative to time-to-event regression. However, the nature of EHD is such that subjects have varying duration of follow-up and some event times may be right censored. However, many ML techniques do not accommodate censoring. Methods: We propose a simple and universal method that allows any ML technique to accommodate right-censored data by averaging predictions over a set of weighted bootstrap samples, where the sampling weights are computed using inverse probability of censoring weighting (IPCW). IPCW is a method that reweights the observed data to represent the underlying population by assigning more weight to observed subjects who were likely to be censored. After resampling from the fully observed data, we fit a model and produce predictions in each iteration. Lastly, we offset computational times by using an ensemble. We consider the problem of predicting 5-year CV risk using EHD from a large health system (N=87,348), where 50% of subjects are censored. We compare our method to other ways of handling censoring. Results: Our technique consistently improved calibration by about 70-90% than approaches which ignored censoring (see below). However, there were no differences in discrimination. In conclusion, we show that miscalibration due to censoring can affect real-world treatment decisions, as demonstrated using the 2013 ACC/AHA treatment recommendation for statins. In such a scenario, one does not aim to identify for example top 10% highest risk patients, but rather the actual magnitude of risk for a single patient.