tbuckley/cabot-search huggingface dataset:
Chapters in American Obstetrics.
Journal: JAMA (1933)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prevalent Vertebral Fracture and the Risk of Incident Vertebral Fracture
Authors: Elizabeth J. Samelson
Journal: JAMA (2008)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Diagnosis of Metastatic Liver Cancer-Reply
Authors: Edward B. Silberstein
Journal: JAMA (1984)

<h3>In Reply.—</h3> I agree with Drs Franco and Schwartz on all points except that of a possible bias toward nuclear medicine. There are quite a number of studies comparing ultrasound, CT, and the radionuclide liver scan in the diagnosis of hepatic metastases, which we have found in preparing a review to be submitted for publication shortly. In comparing modalities, it is important that the instruments being examined are all state-of-the-art equipment at the time of publication so that there is no bias in favor of one modality. The study cited by Franco and Schwartz as a Belgian study (which is actually from Holland) employs a second-generation CT instrument that is obsolete at this time. Similarly, their reference 4 does not indicate which instruments were involved in the radionuclide liver scanning or CT, so, once again, extrapolation of the data is difficult. However, in the fine study performed by Alderson et
Are Outcomes of Surgical Versus Transcatheter Balloon Valvotomy Equivalent in Neonatal Critical Aortic Stenosis?
Authors: Brian W. McCrindle, Eugene H. Blackstone, William G. Williams, Rekwan Sittiwangkul, Thomas L. Spray, Anthony Azakie, Richard A. Jonas
Journal: Circulation (2001)

Background For neonates with critical aortic valve stenosis who are selected for biventricular repair, valvotomy can be achieved surgically (SAV) or by transcatheter balloon dilation (BAV). Methods and Results Data regarding 110 neonates with critical aortic valve stenosis were evaluated in a study by the Congenital Heart Surgeons Society from 1994 to 1999. Reduced left ventricular function was present in 46% of neonates. The initial procedure was SAV in 28 patients and BAV in 82 patients. Mean percent reduction in systolic gradient was significantly greater with BAV (65±17%) than SAV (41±32%; P &lt;0.001). Higher residual median gradients were present in the SAV versus BAV group (36 mm Hg [range, 10 to 85 mm Hg] versus 20 mm Hg [0 to 85 mm Hg], P &lt;0.001). Important aortic regurgitation was more often present after BAV (18%) than SAV (3%; P =0.07). Time-related survival after valvotomy was 82% at 1 month and 72% at 5 years, with no significant difference for SAV versus BAV, even after adjustment for differences in patient and disease characteristics. Independent risk factors for mortality were mechanical ventilation before valvotomy, smaller aortic valve annulus ( z score), smaller aortic diameter at the sinotubular junction ( z score), and a smaller subaortic region. A second procedure was performed in 46 survivors. Estimates for freedom from reintervention were 91% at 1 month and 48% at 5 years after the initial valvotomy and did not differ significantly between groups. Conclusions SAV and BAV for neonatal critical aortic stenosis have similar outcomes. There is a greater likelihood of important aortic regurgitation with BAV and of residual stenosis with SAV.
THE BOOK FORUM
Journal: JAMA (1963)

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<i>On Certain Peculiarities of the Knee-Jerk in Sleep in a Case of Terminal Dementus.</i> By William Noyes, M. D.. Assistant Physician and Pathologist, McLean Asylum. Reprinted from <i>The American Journal of Psychology,</i> Vol. IV, No. 3
Authors: H. M. B.
Journal: American Journal of Psychiatry (1892)
Highlights from this issue
Authors: Andrew Bush, Ian Pavord
Journal: Thorax (2015)

This month's Thorax, coinciding with the American Thoracic Society meeting, has a distinctly USA flavour, not least in the cover picture and the spelling of at least one title (see page 511).Americans, your articles are welcome in Thorax, which is only outranked by the Blue Journal amongst respiratory homes; we challenge you to send us your excellent papers.And secondly, writing in a Prozac-resistant depression after England's dismal world cup performance, anyone for cricket?(But you are not allowed to spoil the fun by practicing!) BOLUS OR BOGUS?
Microscopium
Authors: Lester S. King
Journal: JAMA (1965)

To the blasé scientific public of today the electron microscope can still impart the sense of wonder and admiration that no longer attends light microscopy. The latter is so familiar today that we lose sight of its dramatic development. But the 17th century expressed its wonder in many ways. We can appreciate the earlier attitude only when we understand the way in which the microscope developed. The recent book of Dr. Rooseboom, clearly written and magnificently illustrated, provides just such an understanding. The National Museum for the History of Science, in Leiden, possesses one of the world's great collections of microscopes, a collection which serves as the nucleus around which the book is designed. The exposition is systematic. Dr. Rooseboom traces the development of the various microscope components—the optical parts, the illumination, the arrangement for focusing, the movement of the object in relation to the lens, and the stand. Other
Abstract CT175: HEPANOVA Phase II study design for advanced hepatocellular carcinoma: Tumor treating fields concomitant with sorafenib
Authors: Anca-Ligia Grosu, Eleni Gkika, Thomas Brunner, Robert Thimme, Uri Weinberg
Journal: Cancer Research (2019)

Abstract Background Tumor Treating Fields (TTFields) are a non-invasive, regional antimitotic treatment modality, which has been approved for the treatment of glioblastoma by the FDA. TTFields predominantly act by disrupting the formation of the mitotic spindle during metaphase. TTFields were effective in multiple preclinical models of hepatocellular carcinoma (HCC), leading to a significant increase in cell death. The Phase II HEPANOVA study is the first trial testing TTFields in HCC patients, and is designed to test the safety and efficacy of adding TTFields to sorafenib in advanced HCC. Methods Trial Design: Patients (N=25) with unresectable HCC who are not amenable to any local treatment will be enrolled in this prospective, single-arm study. The study enrolls patients with ECOG score of 0-2 and Barcelona clinic liver cancer (BCLC) stage 0-C. Patients must have a measurable disease per RECIST Criteria. Having implanted electronic devices in the torso is exclusionary. Sorafenib will be administered at standard dose (400 mg daily). TTFields (150 kHz) will be delivered for 18 hours/day until local disease progression per RECIST Criteria. Clinical follow up will be performed q4w, and a CT/MRI scan q12w. Following disease progression in the liver, patients will discontinue TTFields and be followed monthly for survival. Overall response rate will be the primary endpoint and in-field control rate, progression-free survival rate at 12 month (PFS12), OS rate at 1 year and toxicity will all be secondary endpoints. Sample size was calculated using an Exact test for proportions considering the weighted average of ORR of patients who had either complete or partial response per RECIST criteria in historical studies with sorafenib is 4.5%. A sample size of 25 patients was required to achieve a power of approximately 80% at a one-sided alpha level of 0.05 using a single sample Exact test for proportions. Citation Format: Anca-Ligia Grosu, Eleni Gkika, Thomas Brunner, Robert Thimme, Uri Weinberg. HEPANOVA Phase II study design for advanced hepatocellular carcinoma: Tumor treating fields concomitant with sorafenib [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr CT175.
TULAREMIC PERITONITIS
Authors: S. C. FULMER
Journal: JAMA (1927)

There have never been any reports of abdominal complications in tularemia. The spleen, liver and suprarenals seem to bear the brunt of the localized abdominal pathologic changes in this disease, as shown by areas of focal necrosis of the miliary type. This is especially true in infected wild rodents, in which extensive study has been done by Francis and his co-workers during the past fifteen years. In man, however, there has not been ample opportunity to make a thorough pathologic study because of the very low human mortality in tularemia. The examination of the abdominal organs of one patient who died five months after contracting tularemia showed pathologic changes not unlike those of chronic granulomas in the spleen, liver, lungs and suprarenals. The case reported here apparently was an ordinary attack of tularemia until abdominal complications arose three months after the initial infection. The abdominal condition, which resembled that of
ALCOHOL AND MISREPRESENTATION.
Journal: JAMA (1899)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Law and Medicine
Authors: Lawrence O. Gostin
Journal: JAMA (1993)

On the 20th anniversary of<i>Roe v Wade</i>, January 23,1993, President Bill Clinton signed five memoranda that reversed a decade of health law and policy on reproductive rights and medical privacy. First, the Clinton administration suspended a regulation issued on February 2, 1988, that had established standards for family planning services projects funded under Title X of the Public Health Service Act, 42 USC §300<i>et seq</i>, to comply with the statutory prohibition on the use of those funds "in programs where abortion is a method of family planning."<sup>1</sup>The regulations, popularly known as the "gag rule," prohibited federally funded projects from counseling or referring women for abortion. The gag rule was upheld by the Supreme Court in<i>Rust v Sullivan</i>.<sup>2</sup>However, a subsequent interpretation of the rules by the Bush administration, under which physicians could counsel and refer patients regarding abortion but other project employees could not,
Abstract 60: FcR <sup>+</sup> CD4 <sup>+</sup> T Cells as a Specific Subset of IL-17-producing Cells Controlled by BATF/IRF8: Novel Insights Into Etiology of Kawasaki Disease
Authors: Chia-Jung Chang, Tai-Ming Ko, Chien-Hsiun Chen, Jer-Yuarn Wu, Yuan-Tsong Chen
Journal: Circulation (2015)

Kawasaki disease (KD) is an acute vasculitis primarily involved coronary arteries of infants and children. Although more than 40 years have passed since the first description of the disease, its etiology remains unclear. Circulating interleukin 17 is increased in the acute stage of KD and expressed in the damaged coronary arterial wall from autopsies of children after KD. The aim of this study was to elucidate the involvement of IL-17 in the pathogenesis of KD. In this study, we identified a specific subset of CD4 + T cell expressing Fc receptor which existed high percentage in acute stage of KD than in recover stage. In addition, FcR + CD4 + T cell in acute stage expressed higher level of IL-17 than in recover stage. Therefore, we suggest this IL-17-producing FcR + CD4 + T cell may be a critical regulator of immunity in Kawasaki disease. In order to investigate the detail mechanism that FcR + CD4 + T cell subset expressed higher amount of IL-17 in KD, we isolated FcR - CD4 + and FcR + CD4 + T cells from adult healthy donors and stimulated with anti-CD3/CD28 beads only. We found that FcR + CD4 + T cells produced much higher IL-17 than FcR - CD4 + T cells without the need of Th17-differentiation cytokine. Furthermore, FcR + CD4 + T cells expressed higher IL-17-related transcriptional activator, BATF and lower level of transcriptional repress, IRF8 than FcR - CD4 + T cells. Knockdown of BATF and IRF8 could reduce and increase IL-17 production, respectively. These findings define BATF and IRF8 as the intrinsic transcriptional regulators in IL-17 production from FcR + CD4 + T cells. Collectively, our results suggest that IL-17-producing FcR + CD4 + T cells are the novel subset of IL-17-producing cells and important pathogenic immune cells in KD. Inhibition of IL-17 production from FcR + CD4 + T cells has great potential to be as a therapeutic strategy for Kawasaki disease and other FcR + CD4 + T cell-driven autoimmune diseases.
Weight, smoking, and mortality
Authors: J. P. Vandenbroucke
Journal: JAMA (1984)

A controversy has existed concerning the relationship between body habitus and mortality. Original studies found that overweight persons were at risk for increased mortality, but later studies suggested that the very lean were also at high risk. The existence of a U-shaped relationship between mortality and body mass index was confirmed in a reanalysis of a 25-year follow-up of 1,503 men and 1,464 women, initially aged 40 to 65 years. Cigarette smoking did not explain the higher mortality among persons in the lowest body mass index category. (<i>JAMA</i>1984;252:2859-2860)
Erratum
Journal: BMJ (1894)

J. D. M. asks whether a soft water, free from organic impurities, but con- taining 41.5 parts of carbonate soda per 100,000, is to be regarded as wholesome; and, if not, how it can be rendered so ?INQUIRER asks for advice as to the choice of a climate favourable to a patient suffering from from frequent attack of migraine.The patient gas for some years been living in Norfolk, perhaps too dry and bracing a county.She has now the choice of residing in any of the following places: Derby, Bedford, Weymouth, Reading, Dunstable, Worcester, Leamington, Abingdon, Jersey, Guernsey, and London.J. H. asks for suggestions in the treatment of a patient who complains of "coated tongue and a sweetish taste in the.mouth."This has lasted for years, and there are no other symptoms of digestive disorder, the patient being otherwise in apparently good health.Various remedies have been tried, including calomel, rhubarb, and saline purgatives, but with no apparent benefit.M. 0. writes: I should feel greatly obliged if any of your readers could give me a list of books (,I) treating of the fevers of India, (2) tropical diseases, and (3) syphilitic diseases of the nervous system.Nos. ( 1) and ( 2) are required as works of reference in writing a thesis on the subject.**V There has been no book on the fevers of India published since Fayrer's Climate and Fevers of India, and in it the subject is not treated of from the standpoint of the malaria organism of Lavcran.Chevers, Moore, Maclean, Aitken, Morehead, Martin, Annesley-all treat of the fevers of India.(I) Tropical diseases: Davidson's Hygiene and Diseases of Warm Climates is the most recent; Corre's Maladies des Pays Chauds and Roux on the same subject are the most recent French works.Our correspondent will find amplebibliographies In all of these works-parti cularly in the French works.
Alcohol: Its Effects on Man
Journal: JAMA (1934)

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Clinical Obstetrics.
Journal: JAMA (1906)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Atlas and Epitome of Labor and Operative Obstetrics.
Journal: JAMA (1901)

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