tbuckley/cabot-search huggingface dataset:
Osteologist—Not Osteopathist.
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correlative Neurosurgery
Authors: Oscar Sugar
Journal: JAMA (1983)

The abiding virtue of this work is the use of well-illustrated and clearly written neuroanatomy and neurophysiology to help understand the more clinical neurosurgical text. Gross and microscopic, normal and pathological anatomy with numerous diagrams help to illuminate how and why problems arise—and are solved. In this new edition, largely shepherded into print by Dr Schneider, the general plan of earlier editions has been continued. The auctorial and editorial work of the other editors has continued to embellish the text. The text has been expanded from 26 chapters in the second edition (1969) to 39 chapters with 37 authors, largely from the University of Michigan. Radiotherapy for tumors has been written by Wara and Sheline from the University of California at San Francisco. The chapter on stereotaxy has been written by Guiot and Derome from Suresnes, France. David Kline from Louisiana (who trained at Ann Arbor) joined Dr Kahn in
Urea therapy for inappropriate antidiuretic hormone secretion from tuberculous meningitis
Authors: G. Decaux
Journal: JAMA (1980)

THE SYNDROME of inappropriate secretion of antidiuretic hormone (SIADH) can occur in various CNS disorders.<sup>1</sup>Generally, the syndrome disappears when the underlying cause is treated, but treatment can be long or sometimes fails. Symptomatic treatment is necessary for rapid correction of hyponatremia when neurological manifestations are present. The treatment usually recommended is hypertonic saline with or without furosemide.<sup>2</sup>For long-term management of SIADH, water restriction or demeclocycline is used.<sup>3</sup>As urea is known to decrease brain edema<sup>4</sup>and to induce osmotic diuresis,<sup>5</sup>a patient with SIADH secondary to tuberculous meningitis was treated with this drug. Administration of urea rapidly corrected the neurological symptoms and hyponatremia and also proved useful for the long-term management of SIADH despite large fluid intake. <h3>Report of a Case</h3> A 52-year-old man was admitted because of headache. Meningeal signs were present. The computerized tomographic brain scan, funduscopic findings, and chest roentgenogram
Gonococcal proctitis in a married woman. Report of a case
Authors: N. J. Fiumara
Journal: JAMA (1977)

ABOUT 3 million persons in this country acquire gonorrhea each year, according to the US Public Health Service. Many writers have called attention to the increasing problem of gonococcal proctitis in women, especially in those who have cervical gonorrhea.<sup>1-3</sup>The sexual gymnastics of contemporary society make it mandatory for physicians to be aware not only of the many routes of infection, but also of the probable sites involved. <h3>Report of a Case</h3> One Monday morning, an internist from a local hospital asked me to see a married couple whom he had treated for gonorrhea two months earlier. The husband had a recurrence of a purulent urethral discharge and a positive gonococcal smear. He denied vehemently any extramarital exposures. The wife, whom the physician had not examined that morning, just as vehemently protested her innocence. The couple insisted that the discharge could not be of a gonococcal nature, and if
CLINICAL AND ENDOSCOPIC ASPECTS OF METASTASES TO THE GASTROINTESTINAL TRACT
Authors: L Haendchen Bento, M Kazuyoshi Minata, C Pires Batista, R Scomparin, LH Lenz Tolentino, B Costa Martins, F Shiguehissa Kawaguti, E Ryoka Baba, M Simas de Lima, S Naschold Geiger, CMP Simioni Pennacchi, G Andrade de Paulo, R Sato Uemura, CC Gusmon de Oliveira, A Vaz Safatle-Ribeiro, U Ribeiro-Junior, F Maluf-Filho
Journal: Endoscopy (2019)

Characterize the endoscopic aspects of metastases to the gastrointestinal tract and analyze the survival rate of this patients.
General ophthalmic services - a practical alternative.
Journal: BMJ (1978)

level prevailing in Canada, together with a large capital sum to compensate for the years of underspending in building and equipment.Obviously this is economically not feasible.Though I would welcome in theory a fee- for-service method of remuneration, the problems of its implementation within the NHS are such that each unit of service would be so priced by our political masters that the global remuneration of general practitioners would not increase and the level of bureau- cratic interference and paper work would become extremely onerous.Incidentally, when explaining to Canadian colleagues the method of remuneration of NHS general practitioners they thought that a system combining part capitation, part expense reimbursement, and part fee-for-service was absolutely crazy.But they were extremely envious of our inflationproof pension scheme.
STATISTICS OF STATE BOARD EXAMINATIONS
Journal: JAMA (1931)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Umbilical cord blood cells and brain stroke injury: bringing in fresh blood to address an old problem
Authors: Daniel A. Peterson
Journal: Journal of Clinical Investigation (2004)

Degeneration of brain tissue following stroke leads to functional impairment with limited brain self-repair. New evidence suggests that delivery of circulating CD34+ human umbilical cord blood cells can produce functional recovery in an animal stroke model with concurrent angiogenesis and neurogenesis leading to some restoration of cortical tissue. While some alternative interpretations of this data are offered herein, the study provides encouraging evidence of functional recovery from stroke in an animal model using stem cell therapy.
Deaths from spontaneous abortion in the United States
Authors: S. M. Berman
Journal: JAMA (1985)

Little is known about maternal deaths after spontaneous abortion. We studied 122 such deaths reported to the Centers for Disease Control from 1972 through 1980; 21 were intrauterine (contraceptive) device related. The number of non-IUD-related deaths decreased from 15 in 1972 to six in 1980; the mortality ratio (deaths per million live births) decreased from 4.6 in 1972 to 1.7 in 1980. Non-IUD-related deaths were results of infection (48%), hemorrhage (21%), embolism (11%), and other causes (20%). Risk factors for these deaths were age over 29 years, being of minority race, and unmarried status. Most deaths (58%) occurred between 12 and 19 weeks' gestation. The risk of death was much higher for abortion in the second trimester than in the first. Deaths following spontaneous abortion, although rare, do occur; older, black, and unmarried women are at higher risk. (<i>JAMA</i>1985;253:3119-3123)
Reply
Authors: Franfoise Neukirch, Olivier Lyon-Caen, Michel Clanet, Jean Bousquet, Josuo Feingold, Philippe Druet
Journal: Journal of Allergy and Clinical Immunology (1997)

hospitals, whereas underdiagnosis of asthma can be expected in general populations.Our results therefore suggest that subjects with Tin-mediated autoimmune disease are less susceptible to T,2-mediated disorders.We agree with Oro et al. that such findings may have far-reaching implications.Consequently, serum IgE levels should be determined in large samples of patients with MS and control subjects in order to further investigate this hypothesis.
The Coronary Artery Surgery Study
Authors: Gerald M. Lawrie
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE PHILADELPHIA MEETING.
Journal: JAMA (1897)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sulfur granules
Authors: B. Varkey
Journal: JAMA (1982)

An aspirate from a fluctuant interscapular mass found on a 45-year-old man showed "sulfur granules" (Figure, top). He had noted the mass for about one month and had leg ulcers, nonproductive cough, and weight loss for four months. A granule was crushed, Gram stained, and examined under the microscope. Gram-positive branching filaments and a radiating fringe of eosinophilic clubs characteristic of an actinomycotic granule were seen (Figure, bottom). Anaerobic culture of aspirate yielded<i>Actinomyces israelii</i>. Sulfur granules are aggregates of microorganisms admixed with inflammatory debris characteristically but not exclusively found in actinomycosis. Granules vary in color (white to yellow) and size (0.25 to 2 mm in diameter). Sulfur granules may be absent or poorly organized in an occasional case of actinomycosis. Caution should be exercised in interpretation of granules from sputum, since they may be produced by saphrophytic organisms in the tonsillar crypts. Sulfur granules may also be produced by
Use and Interpretation of Diagnostic Immunologic Laboratory Tests
Authors: Kurt J. Bloch
Journal: JAMA (1982)

<h3>ANTIBODIES AND IMMUNOGLOBULINS</h3><h3>Antibodies—The Secreted Products of Plasma Cells</h3> Antibodies are synthesized and secreted primarily by plasma cells, the progeny of B lymphocytes. Since many different clones of cells participate in the immune responses to a single antigen, antibodies are heterogeneous with respect to their structure and function. However, proteins carrying antibody activity, all of which migrate electrophoretically as γ-globulins, belong to different immunoglobulin classes (ie, IgG, IgA, IgM, IgD, and IgE). All immunoglobulins are composed of two polypeptide chains of different molecular size, the light and heavy chains. A monomeric immunoglobulin molecule consists of two heavy and two light chains. These polypeptide chains are arranged in the shape of a Y (Fig 20-1). The arms of the Y are composed of the amino-terminal halves of the heavy chain and the entire light chain, while the carboxyterminal halves of the two heavy chains constitute the stem. The arms and the
Neurobehavioral effects of anticonvulsants
Authors: M. R. Trimble
Journal: JAMA (1991)

A controversial issue in epilepsy research involves the effects of anticonvulsant drugs on cognitive function and behavior. The article by Dikmen and colleagues<sup>1</sup>in this issue ofThe Journalis an important contribution to the subject, especially as it addresses the issue in nonepileptic subjects. Thus, one problem of much work in this area relates to experimental design when the illness in question contaminates the results of any study. Seizures thus impair cognition, and anticonvulsant drugs, by changing seizure frequency, can render interpretation of data difficult. There are several ways to tackle this; one relates to using nonepileptic populations. An earlier attempt in this direction was made by Thompson and colleagues.<sup>2</sup>They used healthy volunteers who were prescribed anticonvulsant drugs in clinically equivalent doses for 14 days, testing cognitive function in a double-blind crossover study against placebo. Phenytoin significantly impaired performance on a variety of tasks, and in
Dynamic Chromatin Modifications Control GnRH Gene Expression during Neuronal Differentiation and Protein Kinase C Signal Transduction
Authors: Anita K. Iyer, Melissa J. Brayman, Pamela L. Mellon
Journal: Endocrine Reviews (2011)

Abstract GnRH, a neuropeptide produced by rare, specialized hypothalamic secretory neurons, is critical for reproduction. During development, GnRH gene expression increases as neurons migrate from the olfactory placode to the hypothalamus, with highest levels in the mature, postmitotic state. While neuronal differentiation is known to be controlled by chromatin modulations, the role of chromatin dynamics in GnRH gene regulation has not been studied. Here, we use mature and immature GnRH neuronal cell models to show that both neuron-specific and protein kinase C regulation of GnRH expression are mediated by chromatin structure and histone modifications. Only in GT1-7 mature GnRH neuronal cells did GnRH regulatory elements display high sensitivity to DNase and enrichment of active histone markers histone-H3 acetylation and H3 lysine 4 trimethylation (H3K4-Me3), as well as RNA Polymerase II (RNAPII) binding and enhancer RNA transcription. In contrast, H3K9-Me2, a marker of inactive chromatin, was highest in nonneuronal cells, low in GT1-7 cells, and intermediate in immature GnRH neuronal cells. The chromatin of the GnRH gene was therefore active in mature GnRH neuronal cells, inactive in nonneuronal cells, but not fully inactive in immature GnRH neuronal cells. Activation of protein kinase C (PKC) potently represses GnRH expression. PKC activation caused closing of the chromatin and decreased RNAPII occupancy at the GnRH minimal promoter (−278/−97). At GnRH-Enhancer-1 (−2404/−2100), PKC activation decreased phosphorylated-RNAPII binding, enhancer RNA transcription, and H3 acetylation, and reciprocally increased H3K9-Me2. Chromatin modifications therefore participate in the dynamic regulation and specification of GnRH expression to differentiated hypothalamic neurons.
Risks vs Benefits in Rheumatology: The Current Status of Drug Therapy
Journal: JAMA (1965)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Varicose Veins.
Authors: B. J. Wethersby
Journal: JAMA (1900)

Wilkesbarre, Pa., July 11, 1900. <h3>To the Editor:</h3> —In the Aug. 7, 1897, issue ofThe Journalwas a short description of an unusual case of varicose veins, together with a photographic cut of the patient. The case was one of compensating dilatation of the superficial epigastric and superficial circumflex iliac veins on both sides of the abdomen, following an attack of phlebitis involving both the right and left femoral veins, which permanently obliterated the lumen of both vessels. The patient died a few days ago from hemorrhage of the stomach. During the past two years he had suffered from dropsy in both legs, the scrotum and abdomen, ulcers on both legs and many other symptoms due to obstruction to the return circulation from the lower limbs. Thinking there might be others who would be interested in knowing how the case has terminated, I submit the above.
Updated Systematic Review and Meta-analysis of the Comparative Data on Colposuspensions, Pubovaginal Slings, and Midurethral Tapes in the Surgical Treatment of Female Stress Urinary Incontinence
Authors: Ferdinando Fusco, Mohamed Abdel-Fattah, Christopher R. Chapple, Massimiliano Creta, Sabrina La Falce, David Waltregny, Giacomo Novara
Journal: European Urology (2017)
Newest in long tradition of hospital ships originally were launched as supertankers
Authors: C. Raymond
Journal: JAMA (1989)

HAVE HOSPITAL, will travel. Plowing steadily through the waters of the Pacific and Atlantic oceans, respectively, the US Navy hospital ships<i>Mercy</i>and<i>Comfort</i>provide floating medical support for military personnel—and civilians, too. In 1986, for example, the<i>Mercy</i>went on a 72-day shakedown cruise in the Philippines as part of a humanitarian aid package approved by then-President Ronald Reagan. The 90 000-ton (81 000 tonne) ship stopped at seven islands to treat as many as 1500 persons a day for ailments ranging from leprosy to parasites, malaria, and tumors. "The biggest one [tumor] was 32 pounds and the size of a basketball," recounts CDR Judith Lombardi. Many of the children who came on board had cleft lips and palates, clubfeet, or cataracts. Working with local physicians, the medical staff preselected patients to fit into the ship's capability and overall mission. Certainly, the problems of the patients on the Philippine
Moratorium or More
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Phase II Trial of erlotinib (OSI-774) in patients with hepatocellular or biliary cancer
Authors: P. A. Philip, M. Mahoney, J. Thomas, H. Pitot, R. Donehower, G. Kim, J. Picus, T. Fitch, S. Geyer, C. Erlichman
Journal: Journal of Clinical Oncology (2004)

4025
A MEDICOLEGAL CLASSIC
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal