tbuckley/cabot-search huggingface dataset:
Comparison of sensitivity to ultraviolet B irradiation between human lymphocytes and hematopoietic stem cells
Authors: Hiroshi Azuma, Kenji Ikebuchi, Miki Yamaguchi, Hideaki Murahashi, Yuko Mogi, Norihiro Sato, Mitsuhiro Fujihara, Fumiya Hirayama, Hisami Ikeda
Journal: Blood (2000)
Germany's Health Care System
Authors: John K. Iglehart
Journal: New England Journal of Medicine (1991)

Germany's universal health insurance plan is grounded in a social contract that places a strong emphasis on the provision of medical care to all citizens by private ambulatory care physicians who largely have clinical autonomy but who have relinquished their economic freedom to the professional associations that negotiate on their behalf with insurance organizations known as sickness funds. Hospital-based physicians, who are employees of the institutions for which they work, are paid by salary. Germany's health system is administered by private not-for-profit organizations, authorized by law to wield power on behalf of payers and providers. The federal government intervenes only . . .
Effects of Cadmium and Zinc on Tissue Levels of Metallothionein
Authors: S. Onosaka, K. Tanaka, M. G. Cherian
Journal: Environmental Health Perspectives (1984)

Although the induced synthesis of metallothionein (MT) after exposure to certain metals has been known for some time, there is little information on the quantitation of MT in various tissues. In this study, tissue MT concentrations were measured by a modified Cd-saturation method in tissues of adult male rats after injection of different metal salts. There were differences in tissue levels of MT, depending on the injected metals. Of all the metals studied, Cd2+ was the most effective element in increasing MT concentrations in liver, kidney, pancreas and small intestine. The highest increase in tissue MT concentration after CdCl2 injection was found in the liver, while the pancreas contained the highest MT level after ZnSO4 injection. Co and Ni salts increased MT levels in both liver and kidney, while Mn and Ca increased MT levels only in liver. A direct correlation between tissue MT levels and Cd or Zn concentration was observed in most of the tissues after injection of CdCl2 or ZnSO4. Although there was no positive relationship between tissue levels of MT and tissue Mn and Ni concentrations, the increase in hepatic Zn after injection of these metals was related to hepatic MT levels. The tissue distribution of injected Cd2+ in control adult rats and Zn-deficient rats was similar. However, there was no increase in pancreatic MT levels in Zn-deficient rats after injection of CdCl2. The high concentration of MT in pancreas after ZnSO4 injection in adult rats and the inability of the pancreas to synthesize MT in Zn-deficient rats suggest that the induction of pancreatic MT synthesis is sensitive to Zn status.(ABSTRACT TRUNCATED AT 250 WORDS)
Wieger’s ligament
Authors: David McLeod
Journal: Ophthalmology (2003)

Based on their recent experience of endoscopic methods for separation of Wieger's ligament from the posterior lens capsule, Torii and colleagues feel that surgical manipulation of the anterior hyaloid membrane warrants further investigation, for example in diabetic vitrectomy.1 However, there is already a long (20 year) experience of such mechanical modulation of the behaviour of the aschaemic diabetic eye postvitrectomy.2,3 The rationale was founded upon (1) the ready separation of the anterior vitreous face from the lens during intracapsular cataract extraction in older patients, (2) the observation of Michels that drainage of red blood cells through the trabecular meshwork and a clear vitreous cavity are characteristic features of the aphakic vitrectomised diabetic eye, albeit with a high risk of rubeosis iridis,4 and (3) the introduction of scatter endophotocoagulation in the early 1980s to reduce the aschaemic drive to neovascularisation following vitrectomy.5
SCIENTIFIC WORK IN THE PHILIPPINES.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Treatment of primary moderate hypercholesterolemia with lovastatin (mevinolin) and colestipol
Authors: G. L. Vega
Journal: JAMA (1987)

The introduction of inhibitors of cholesterol biosynthesis offers a new approach to treatment of hypercholesterolemia. One such agent, lovastatin (formerly, mevinolin), causes significant reductions in plasma cholesterol levels. This action can be enhanced by bile acid sequestrants. In this study, lovastatin and colestipol hydrochloride together were administered to ten patients with primary moderate hypercholesterolemia. Compared with a control period, the combined-drug therapy caused a 36% reduction in plasma total cholesterol level, a 48% decrease in low-density lipoprotein (LDL) cholesterol level, and a 17% increase in high-density lipoprotein cholesterol level. The reduction in LDL cholesterol level was due to three factors: (1) a 27% decrease in the production rate of LDL, (2) a 20% increase in fractional catabolic rate of LDL, and (3) a 15% depletion of cholesterol in LDL particles. This major reduction in LDL cholesterol level produced by combined-drug therapy may be valuable for prevention of coronary heart disease in high-risk patients with primary moderate hypercholesterolemia. (<i>JAMA</i>1987;257:33-38)
THE DUAL BRAIN.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Emergence of ESBL-producing<i>Escherichia coli</i>and<i>Klebsiella pneumoniae</i>isolates during the years 2000 and 2004 in Helsinki, Finland
Authors: Sofia D. Forssten, Elina Kolho, Anneli Lauhio, Laura Lehtola, Sointu Mero, Anna Oksaharju, Jari Jalava, Eveliina Tarkka, Martti Vaara, Jaana Vuopio-Varkila
Journal: Clinical Microbiology and Infection (2009)
Medical information science. A joint endeavor
Authors: T. L. Lincoln
Journal: JAMA (1983)

IN THE 1970s, computers evolved into sophisticated information processing and communication systems. The 1980s will demonstrate the full impact of what they can do. Much has been written about the implications of this new electronic revolution,<sup>1-5</sup>and the outlines of a new information processing world are now evident. Today we may confidently project a new generation of computer systems that will accommodate the full functional diversity that health professionals require as end users of information. Equipment exists,<sup>6</sup>dramatic examples can be demonstrated,<sup>7,8</sup>and the price is almost right. Without preempting the expertise of the systems designers who will be responsible for providing new working systems, the future should look something like this: large mainframe computers will concern themselves with bulk tasks, eg, managing common archives and reorganizing large files, mainframe satellites will be involved in printing extensive batch reports, and communication nodes will link the archives with
Dispensaries: Their Management and Development. A Book for Administrators, Public Health Workers, and All Interested in Better Medical Service for the People.
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
THE WORK OF THE PRINCIPAL SECTIONS.
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Missing Byline Author
Authors: Jui-Feng Tsai, Hutan Ashrafian
Journal: JAMA Psychiatry (2015)

Bradley S. Peterson, MD; Virginia A. Rauh, ScD; Ravi Bansal, PhD; Xuejun Hao, PhD; Zachary Toth, BA; Giancarlo Nati, BA; Kirwan Walsh, BA; Rachel L. Miller, MD; Franchesca Arias, MS; David Semanek, BA; Frederica Perera, DrPH, PhD
Book Review Essentials of Pathology . By Lawrence W. Smith, M.D., and Edwin S. Gault, M.D. With a foreword by James Ewing, M.D. Second edition. 4°, cloth, 960 pp., with 685 illustrations and 13 color plates. New York: D. Appleton-Century Company, Incorporated, 1942. $10.00.
Journal: New England Journal of Medicine (1943)
Senile lens exfoliation
Authors: P. M. Fiore
Journal: JAMA (1990)

An 86-year-old man complained of decreasing vision in his left eye. He has had poor vision in his right eye since he was a child. Visual acuity was counting fingers at 1 ft OD and 20/60 OS. Slit-lamp examination revealed bilateral brunescent cataracts. Also present bilaterally was a thin, clear membrane that protruded through the pupil to float in the anterior chamber. The membrane was attached to the anterior lens capsule and was best seen with retroillumination (Fig 1). The patient denied any history of ocular trauma or occupational exposure to excessive heat or infrared radiation. He underwent uneventful extracapsular cataract extraction with posterior chamber intraocular lens implantation in his left eye. The anterior lens capsule was sent for analysis. Histopathologic examination revealed an eosinophilic amorphous substance with a periodic acid-Schiff—positive membrane. At high magnification the membrane showed multiple splitting of the anterior lens capsule (Fig 2). True lens exfoliation
Pulmonary Embolism
Authors: James E. Dalen
Journal: JAMA (1969)

Few diseases are as common, as potentially lethal, and yet as frequently unrecognized as pulmonary embolism. When pulmonary emboli have been carefully sought at postmortem examination, the incidence has been found to be in excess of 25%.<sup>1-3</sup>At the Peter Bent Brigham Hospital, pulmonary embolism is one of the three most common causes of death.<sup>1</sup>Yet, the correct premortem diagnosis is made in only about 50% of the cases. The number of deaths due to pulmonary embolism may be decreased by early recognition and prompt treatment, thus minimizing the risk of additional episodes of potentially lethal embolism. <h3>Recognition of Pulmonary Embolism</h3> The well-known difficulty in recognizing pulmonary embolism is, in part, due to the fact that it can present as four different clinical syndromes: <h3>1. Pulmonary Infarction.—</h3> Although pulmonary infarction is the most familiar manifestation of pulmonary embolism, it is one of the least frequent complications of embolism.
Cephalexin-related nephropathy
Authors: S. Verma
Journal: JAMA (1975)

Hematuria and eosinophilia developed in two patients being treated for bacterial endocarditis with 20 or 24 gm/day of cephalexin given orally together with probenecid (Benemid). One patient had a concurrent transient increase in serum creatinine; both patients had a history of penicillin allergy and had previously received cephalexin intravenously. All abnormalities promptly remitted following discontinuation of therapy. (<i>JAMA</i>234:618-619, 1975)
Excess iron induces hepatic oxidative stress and transforming growth factor β1 in genetic hemochromatosis
Authors: K Houglum
Journal: Hepatology (1997)

Genetic hemochromatosis (GH) is associated with excess iron deposition in hepatocytes, which results in progressive hepatic injury. The pathogenesis of hepatic injury in GH is poorly understood. In this study, we found enhanced oxidative stress in patients with GH, as evidenced by hepatic malondialdehyde (MDA)-protein adducts and by increased oxidatively modified serum proteins. MDA-lysine epitopes and oxidatively modified serum proteins, as well as immunoglobulin G autoantibodies against MDA-lysine epitopes, were increased in untreated GH patients and to a lesser extent in GH heterozygotes compared with normal individuals. These markers of ongoing oxidative stress decreased with phlebotomy treatment in GH patients. In addition, TGF-β1 colocalized with hepatic iron and MDA protein adducts in hepatocytes and sinusoidal cells of hepatic acinar zone 1 and normalized after iron removal. Our data suggest that iron overload increases both lipid peroxidation and TGF-β1 expression, which together could promote hepatic injury and fibrogenesis.
The Glaucoma Laser Trial (GLT)
Journal: Ophthalmology (1990)

The Glaucoma Laser Trial, a multicenter, randomized clinical trial involving 271 patients, was designed to assess the efficacy and safety of argon laser trabeculoplasty (ALT) as an alternative to treatment with topical medication for controlling intraocular pressure (IOP) in patients with newly diagnosed, previously untreated primary open-angle glaucoma (POAG). Each patient had one eye randomly assigned to ALT (the laser first [LF] eye) and the other eye assigned to timolol maleate 0.5% (the medication first [MF] eye). Medication was initiated or changed for either eye according to the same stepped regimen if the IOP was not controlled. Throughout the 2-year follow-up, LF eyes had lower mean IOPs than MF eyes (1-2 mmHg), and fewer LF eyes than MF eyes required simultaneous prescription of two or more medications to control IOP (P < 0.001). After 2 years of follow-up, 44% of LF eyes were controlled by ALT, 70% were controlled by ALT or ALT and timolol, and 89% were controlled within the stepped medication regimen. After 2 years, 30% of MF eyes remained controlled by timolol, and 66% were controlled within the stepped regimen. There were no major differences between the two treatment approaches with respect to changes in visual acuity or visual field over the 2 years of follow-up.
Correction: Diagnostic performance of congestion score index evaluated from chest radiography for acute heart failure in the emergency department: A retrospective analysis from the PARADISE cohort
Authors: Masatake Kobayashi, Amine Douair, Kevin Duarte, Déborah Jaeger, Gaetan Giacomin, Adrien Bassand, Victor Jeangeorges, Laure Abensur Vuillaume, Gregoire Preud’homme, Olivier Huttin, Faiez Zannad, Patrick Rossignol, Tahar Chouihed, Nicolas Girerd
Journal: PLoS Medicine (2021)
Rapid serum lidocaine determination in the coronary care unit
Authors: S. M. Deglin
Journal: JAMA (1980)

Eighty-four serum lidocaine determinations were made in 33 hospitalized patients with the use of a rapid enzyme immunoassay technique. Prediction of lidocaine concentration within broad categories based on clinical assessment alone was compared with actual measurements. When serum concentrations were not considered, most episodes of lidocaine toxic reactions were obscured by associated complex clinical problems. The rapid lidocaine enzyme immunoassay is a useful tool for assisting in the detection of lidocaine toxic reactions in the coronary care unit. (<i>JAMA</i>244:571-573, 1980)
THE DUTIES OF THE COUNCILLORS.
Journal: JAMA (1902)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Tobacco product liability
Journal: JAMA (1986)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Recovery from acute intestinal ischemia without bowel resection
Authors: J. K. Vyden
Journal: JAMA (1973)

Although intestinal infarction is often the result of a sudden massive occlusion of the superior mesenteric artery or vein, it also sometimes is caused by nonocclusive vascular insufficiency of the intestine secondary to a low cardiac output state. Such patients should be managed by vigorously treating the cause of the low cardiac output rather than undertaking resection of the bowel, which is seldom successful because the circulation is insufficient to permit primary healing.
Chronic Disease Control Activities of Medical and Dental Organizations
Journal: JAMA (1988)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal