tbuckley/cabot-search huggingface dataset:
Risk Stratification after Myocardial Infarction
Authors: Eric D. Peterson
Journal: Annals of Internal Medicine (1997)

Letters1 December 1997Risk Stratification after Myocardial InfarctionEric D. Peterson, MD, Leslee J. Shaw, PhD, and Robert M. Califf, MDEric D. Peterson, MDDuke University Medical Center; Durham, NC 27705, Leslee J. Shaw, PhDDuke University Medical Center; Durham, NC 27705, and Robert M. Califf, MDDuke University Medical Center; Durham, NC 27705Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-127-11-199712010-00025 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Horton raises two important questions about the care of patients with uncomplicated myocardial infarction: length of stay and whether a stress perfusion imaging study is necessary before hospital discharge. Although it is true that our specific recommendations have yet to be tested in large randomized trials, we can already estimate the potential outcomes and costs associated with this strategy on the basis of information available from large myocardial infarction registries. For example, one can assess the cost-effectiveness of inpatient stays beyond hospital day 5 (for example, staying 7 versus 5 days) in patients with uncomplicated myocardial infarction. ...References1. Mark DB, Mark DB, Hlatky MA, Califf RM, Naylor CD, Lee KL, et al. Cost effectiveness of thrombolytic therapy with tissue plasminogen activator versus streptokinase for acute myocardial infarction: results from the GUSTO randomized trial. N Engl J Med. 1995; 332:1418-24. Google Scholar2. Mark DB. Medical economics and health policy issues for interventional cardiology. In: Topol EJ, ed. Textbook of Interventional Cardiology. 2d ed. Philadelphia: WB Saunders; 1993:1323-53. Google Scholar3. Peterson ED, Shaw LJ, Califf RM. Risk stratification after myocardial infarction. Ann Intern Med. 1997; 126:561-82. Google Scholar4. American College of Physicians. Guidelines for risk stratification after myocardial infarction. Ann Intern Med. 1997; 126:556-60. Google Scholar Author, Article, and Disclosure InformationAuthors: Eric D. Peterson, MD; Leslee J. Shaw, PhD; Robert M. Califf, MDAffiliations: Duke University Medical Center; Durham, NC 27705 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoRisk Stratification after Myocardial Infarction Heather L. Horton Metrics Cited byA Call for Pharmacists to Improve the Care of Patients with Myocardial Infarction 1 December 1997Volume 127, Issue 11Page: 1040-1041KeywordsDeath ratesExercise therapyHeartHospitalizationsInpatientsLength of stayLife expectancyMyocardial infarctionPostmyocardial infarctionRandomized trials ePublished: 15 August 2000 Issue Published: 1 December 1997 Copyright & PermissionsCopyright © 1997 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
New Journal: &lt;italic&gt;Laboratory Animals&lt;/italic&gt;
Journal: JNCI Journal of the National Cancer Institute (1967)

New Journal: Laboratory Animals JNCI: Journal of the National Cancer Institute, Volume 39, Issue 1, July 1967, Page 172, https://doi.org/10.1093/jnci/39.1.172 Published: 01 July 1967
An Address ON WOUND INFECTIONS; AND ON SOME NEW METHODS FOR THE STUDY OF THE VARIOUS FACTORS WHICH COME INTO CONSIDERATION IN THEIR TREATMENT: Delivered before the Royal Society of Medicine on March 30th
Authors: A. E. Wright
Journal: BMJ (1915)

TlE BEITIsH ] 8 OUND INFECTIONS.[MAY reaches the cell at too low a p)ressire, and in this they perlhaps differ to somle extent fromn the, as yet, uninvesti- gated causes of oxvygen walnt 1, 2, and 4.Let me niow redeem] mily promuise to say a word about niomenclature.If my argument proves anyvtlling, it proves that there is a type of dyspnoea to which tlhe adjective "renal " ulay jtustly be applied.It is renal because this stimulus to the respiratory centre is tlle direct result of oxygen want in tlle kidney, the intermediary between the one and the otlher being tlle reaction of-tlle blood.Thei degree of dyspnoea which will be produced by a giveln accomplislhment on the part of the kidney will depend npon the irritability of the respiratory centre-for tlhis, acecordingy to tlle admirable work both of Dr. Poulton6s in this country and of Dr. Peabody7 in America, seemis capable of fluctuation in renal cases.Onl tlle side of treatment there would seenm to be a theoretical case for tlle consideration of oxygen, at all events wlhen the patient is in great distress.That is to say, the distress might be alleviated whilst the patient was breathing tlle gas.The limitations of such treat- ment, however, are as great as the limitations of our pre- sent mliethods for the administration of the gas.Stell, then, is the last of my tlhree comparisons; if, as I lhope, it may contain somiiething that is useful, a justification in practice would be found for the view on wlicih the comparison is based-the view that in the " adaptations " of the body to special sets of circumstances there lies the germof certain "chemical lesions," the view tllat the p)atbological is sometimues rather tlle exaggeration of the physiological tllan its antitlhesis.
Contents
Authors: George Bartley, Yong-Min Choi, Seung-Hyun Kim, Takahiro Hiraoka, Kazunori Miyata, Yasuko Nakamura, Takashi Miyai, Miyuki Ogata, Fumiki Okamoto, Tetsuro Oshika, Anna Carrigan, Lindreth Dubois, Maartje Van Bree, Thomas Van Den Berg, Bart Zijlmans, Jun Cheng, Xiaolin Qi, Jing Zhao, Hualei Zhai, Lixin Xie, Pedram Hamrah, Andrea Cruzat, Mohammad Dastjerdi, Harald ¨ss, Lixin Zheng, Bashar Shahatit, Hasan Bayhan, Reza Dana, Deborah Pavan-Langston, Monisha Nongpiur, Benjamin Haaland, David Friedman, Shamira Perera, Mingguang He, Li-Lian Foo, Mani Baskaran, Lisandro Sakata, Carol Shields, Sanket Shah, Carlos Bianciotto, Jacqueline Emrich, Lydia Komarnicky, Jerry Shields, Clement Tham, Yolanda Kwong, Nafees Baig, Dexter Leung, Felix Li, Dennis Lam, David Garway-Heath, Gerassimos Lascaratos, Catey Bunce, David Crabb, Richard Russell, Ameet Shah, Renyi Wu, Yim-Lui Cheung, Mei Saw, Paul Mitchell, Tin Aung, Ryo Kawasaki, Jin Wang, Elena Rochtchina, Anne Lee, Tien Wong, Yuki Muraoka, Akitaka Tsujikawa, Tomoaki Murakami, Ken Ogino, Kyoko Kumagai, Kazuaki Miyamoto, Noriko Yoshida, Yasuhiro Ikeda, Shoji Notomi, Keijiro Ishikawa, Yusuke Murakami, Toshio Hisatomi, Hiroshi Enaida, Tatsuro Ishibashi, Joan Miller, Jennifer Le Couter, Erich Strauss, Napoleone Ferrara, Farshad Abedi, Sanjeewa Wickremasinghe, Andrea Richardson, Enes Makalic, Daniel Schmidt, Sukhpal Sandhu, Paul Baird, Robyn Guymer
Journal: Ophthalmology (2012)
Inhaled Particles in Human Disease and Animal Models: Use of Electron Beam Instrumentation
Authors: Arnold R. Brody
Journal: Environmental Health Perspectives (1984)

The mineral pneumoconioses (lung disease caused by inhalation of inorganic dust) have been an important disease entity for centuries. In the last several decades, the electron microscope has been used to elucidate the distribution and identification of inhaled minerals, to aid in establishing etiologic factors, and less commonly, to determine the basic biologic mechanisms through which inhaled minerals cause lung disease. In this section, I review the instrumentation and tissue preparation currently used to address some modern problems in particle-induced lung disease. For example, human pneumoconioses of undetermined etiology can be clarified by electron microscopy and X-ray energy spectrometry. In addition, the initial deposition patterns of asbestos and silica are demonstrated in animal models, and the contributions of electron microscopy in establishing the initial lesions of asbestosis are described.
Methylmalonate Excretion in a Patient with Pernicious Anemia
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Rubella booster immunization. Serologic response to a second dose of vaccine
Authors: S. A. Wyll
Journal: JAMA (1971)

To determine the persisting effect on base-line antibody levels of a booster dose of rubella vaccine, blood specimens were obtained eight to ten weeks following revaccination from 92 study children immunized initially in July 1968. Only six of 92 (6.5%) revaccinees demonstrated a fourfold or greater rise in rubella hemagglutination-inhibiting (HI) antibody titer. The HI titers before administration of the booster dose were low in all six (1:32 or less); however, similar low titers were noted in 33 revaccinees who demonstrated no increase in antibody. These data suggest that a second dose of rubella vaccine given approximately two years following primary immunization does not significantly increase antibody levels and, therefore, may be ineffective in enhancing resistance to reinfection.
A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans
Authors: Hui Li, Hui Xie, Wei Liu, Rong Hu, Bi Huang, Yan-Fei Tan, Kang Xu, Zhi-Feng Sheng, Hou-De Zhou, Xian-Ping Wu, Xiang-Hang Luo
Journal: Journal of Clinical Investigation (2010)
Semiologia dos Sopros Diastolicos da Base. Especial Estudo da Insufficiencia Aortica Myocardica.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Oral Surg, Oral Med and Oral Path, St. Louis
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
A clinical trial of a behavioral therapy to reduce urinary incontinence in nursing homes. Outcome and implications
Authors: T. W. Hu
Journal: JAMA (1989)

One hundred thirty-three incontinent women in seven nursing homes were assigned randomly to a 13-week behavior therapy program for urinary incontinence or to a control group that received usual incontinence-related care. The therapy became effective after 6 weeks of training. By the final month of training, the treatment women's wet episodes had been reduced by 0.6 episodes per day, a 26% reduction over baseline. This reduction in the number of wet episodes was statistically significant, both with respect to this group's baseline levels of incontinence and in comparison with the performance of the control women. The number of wet episodes in the control group remained about the same throughout training and the 22-week follow-up period. The treatment women improved partly because they learned to request help, a response prompted and reinforced by the program. Trainees with a high frequency of incontinence during baseline, the more cognitively intact residents, and residents with normal bladder capacity responded better to this behavior therapy program. (<i>JAMA</i>. 1989;261:2656-2662)
Payment of Members of District Management Teams
Authors: C. D.M.T. Member
Journal: BMJ (1974)

Married Women Consultants SnI,-In all the letters and discussion about 10-session contracts for consultants and whether or not private practice should be allowed I have seen no mention of maried women consultanir who, like my- self, elect to do maximum part-tmne work not to do private practice but so that they can have a modest amounit of
Marijuana
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Chemotherapy
Authors: Aimée Grunberger
Journal: JAMA (1995)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Half Her
Authors: Henry Bair
Journal: JAMA (2020)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Thyroid function test (TFT) abnormalities in patients (pts) with metastatic renal cell carcinoma (RCC) treated with sorafenib
Authors: I. R. Tamaskar, J. Unnithan, J. A. Garcia, R. Dreicer, L. Wood, A. Iochimescu, R. Bukowski, B. Rini
Journal: Journal of Clinical Oncology (2007)

5048 Background: Sorafenib is an orally bioavailable VEGF receptor inhibitor with anti-tumor activity in metastatic RCC. Sunitinib, another VEGF receptor inhibitor, induces biochemical hypothyroidism in 85% of metastatic RCC pts, the majority of whom have signs or symptoms of hypothyroidism (Rini BI et al. JNCI 2007 99(1):81–83). Thus, the incidence of TFT abnormalities in pts with metastatic RCC receiving sorafenib was investigated. Methods: The medical records of pts with metastatic RCC receiving sorafenib in one of five clinical trials at the Cleveland Clinic Taussig Cancer Center were reviewed. TFTs (TSH, T4, FTI and T3), patient demographics and clinical outcomes were recorded. Results: Between February 2004 and November 2006, 71 pts (49 males, 22 females) were treated with sorafenib. Baseline pt characteristics included a median age of 62 years (range, 35–87), 87% of pts had clear cell histology and 97% had prior nephrectomy. Forty-two pts had TFTs measured while receiving sorafenib and 19/42 pts (45%; 95% CI: 30–61%) had abnormal TFTs. The TFT abnormalities were consistent with hypothyroidism (13 pts), euthyroid sick syndrome (2 pts) or hyperthyroidism (4 pts). The median values in pts with abnormal TFTs were: TSH-7 μU/ml, T3–79 ng/dl, T4–12.7 μg/dl, FTI- 5.4; these values are just outside the normal laboratory ranges. The majority of pts did not have clinical signs or symptoms that could be attributed solely to thyroid dysfunction; only one pt (2%) received thyroid hormone replacement. The estimated progression free survival for pts with normal TFTs is 7.5 months vs. 6.1 months for pts with abnormal TFTs (p=0.79). Conclusion: Mild biochemical TFTs abnormalities are common in pts with metastatic RCC treated with sorafenib. However, severe TFT abnormalities and/or clinical signs/symptoms of thyroid dysfunction are not seen, and thyroid replacement therapy is not often indicated. In contrast to sunitinib, where the high incidence and clinical relevance of thyroid dysfunction requires routine monitoring, pts with metastatic RCC receiving sorafenib should have TFTs monitored only if clinically indicated. [Table: see text]
Serial studies on circulating immune complexes in post-streptococcal sequelaeVan de Rijn, I., Fillit, H., Brandies, W. E., Reid, H., Poon-King, T., McCarthy, M., Day, N. K. and Zabriskie, J. B. (1978). Clinical and Experimental Immunology, 34, 318
Journal: Journal of Infection (1981)
Workshop Conference on Hyperthermia in Cancer Treatment
Journal: JNCI Journal of the National Cancer Institute (1985)

Journal Article Workshop Conference on Hyperthermia in Cancer Treatment Get access JNCI: Journal of the National Cancer Institute, Volume 74, Issue 2, February 1985, Page 541, https://doi.org/10.1093/jnci/74.2.541 Published: 01 February 1985
Plague.
Journal: BMJ (1983)

istic of an intradural tumour, which was worse on lying down, could be walked off, and was aggravated by coughing and sneezing.The diligent examiner may find unilateral weakness of the abdominal muscles and diminution of the abdominal reflex in these cases.Patients with diabetes are known to suffer abdominal pains from thoracic radiculopathy3 but the onset of back pain in these patients should always suggest an epidural abscess until proved otherwise.The presentation may be subacute, as in case 1, with no objective neurological signs.Waiting for such signs to evolve may result in disastrous cord infarction.Children are another group of patients in whom recurrent abdominal pains may be the initial symptom of a spinal cord tumour and be misdiagnosed as abdominal migraine or abdominal epilepsy.4The well known difficulties of examining children should never prevent a neurological examination in atypical abdominal pain.
Observations on the Immediate Response of Paramecium to Mixtures of Aerosol-Acetone and Aerosol-Acetone-Methylcholanthrene
Authors: George E. Daniel
Journal: JNCI Journal of the National Cancer Institute (1946)

Observations on the Immediate Response of Paramecium to Mixtures of Aerosol-Acetone and Aerosol-Acetone-Methylcholanthrene George E. Daniel George E. Daniel special research fellow National Cancer Institute, National Institute of Health, United States Public Health Service Search for other works by this author on: Oxford Academic PubMed Google Scholar 1The author is indebted to Mrs. Dorothy Peterson, Physics Section, Industrial Hygiene Research Laboratory, of the National Institute of Health, for making the ultraviolet absorption determinations. Author Notes JNCI: Journal of the National Cancer Institute, Volume 7, Issue 3, December 1946, Pages 123–126, https://doi.org/10.1093/jnci/7.3.123 Published: 01 December 1946 Article history Received: 29 October 1946 Published: 01 December 1946