Improving Protection against Infection in People without Enough Immunoglobulin
Journal: Annals of Internal Medicine (2001)

Summaries for Patients7 August 2001Improving Protection against Infection in People without Enough ImmunoglobulinSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-135-3-200108070-00004 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail What is the problem and what is known about it so far?The ability to resist infection depends on many factors, including proteins in the blood, known as immunoglobulins, that help kill bacteria and viruses. Some people cannot make enough immunoglobulin and need regular intravenous injections of immunoglobulin to protect them from infection. Although standard replacement doses of immunoglobulins decrease the number of infections, some infections continue to occur despite this treatment.Why did the researchers do this particular study?To see if doubling the standard dose of intravenous immunoglobulin reduces the number and duration of infections in people who ... Author, Article, and Disclosure InformationAffiliations: The summary below is from the full report titled “The Effect of Two Different Dosages of Intravenous Immunoglobulin on the Incidence of Recurrent Infections in Patients with Primary Hypogammaglobulinemia. A Randomized, Double-Blind, Multicenter Crossover Trial.” It is in the 7 August 2001 issue of Annals of Internal Medicine (volume 135, pages 165-174). The authors are HW Eijkhout, JWM van der Meer, CGM Kallenberg, RS Weening, JT van Dissel, EAM Sanders, PFW Strengers, H Nienhuis, and PThA Schellekens, for the Inter-University Working Party for the Study of Immune Deficiencies.Summaries for Patients are a service provided by Annals to help patients better understand the complicated and often mystifying language of modern medicine.Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician. The summaries may be reproduced for not-for-profit educational purposes only. Any other uses must be approved by the American College of Physicians-American Society of Internal Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoThe Effect of Two Different Dosages of Intravenous Immunoglobulin on the Incidence of Recurrent Infections in Patients with Primary Hypogammaglobulinemia Heleen W. Eijkhout , Jos W.M. van der Meer , Cees G.M. Kallenberg , Ron S. Weening , Jaap T. van Dissel , Lieke A.M. Sanders , Paul F.W. Strengers , Henriët Nienhuis , Peter Th.A. Schellekens , and Metrics 7 August 2001Volume 135, Issue 3Page: I-26KeywordsAntibioticsBacteriaBloodFeversHeadachesImmune deficiencyIntravenous immunoglobulinIntravenous injectionsProteins ePublished: 7 August 2001 Issue Published: 7 August 2001 Copyright & PermissionsCopyright © 2001 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...