tbuckley/cabot-search huggingface dataset:
Observations on Suprapubic Lithotomy
Authors: W. Mac Cormac
Journal: BMJ (1887)

ITHE BRITI.MJ?pIC4N JOUBNAL.-trQduce$l into the rectum.l3unt -hooksj a-nd a speia gorgt (~ig. 1) OBSERVATIONS *~~~~~~~~ere used for holditig the blaidder',iup ''gf%t bwhg-'opeaed, but the OBSER'VATIONS.~~~f o r e f i n t g e r ' of the left Mi~d is preferable-to6 auy'form of instrument.In' ON SUPIRAP1IJJ~~~IC LITHOTOIMY.~~order t6 afford addition'al,spa e,' transverse indi6ions were sometimes' pta:ctisedl in' the ,deepet structures, eithe'r the aponeurosis or the A Paier rderd ~~~~~~~~~~~~~~~~~~~~bef ore h' Hrei6`Sorciety of London', Februa'ry, "188 'muscles; but thesei dre mrarly nedu,adte ote BySin WILLIAM MA-C CORMAQI-F.R. C.S., ocirenc fhrna rtuso hogh the cicatrix.'In' no case' ~~1,.1, was an, attempt e#er made to el6se the 'vesical wound;-charpie or un"~', Surgeon to, and Lectureron Surgery at, at.ToasHsptLravelled linen As passed fromnth6exete'rnal surface to the bto f Mn.PnEIJXENT ND GENrsRnN,-Iowe theSocietythe bladder,, ad the dressings renewed thtee er more times a day.MIL -REIDETAD GNTLX1N--JowetheSocetyan. apology,fer addreseing it upon a s'ubject of which I hlave but ai l'imited pers6nAl.h9~q difiw bel'iv' 8
The Lymphatics of the Heart
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Correspondence
Authors: Richard H. Egdahl
Journal: JAMA (1974)

<h3>Sir.—</h3> Since I am the editor who selected Dr. Paloyan and his group for the monograph on hyperparathyroidism that was somewhat critically reviewed by Drs. Cope and Goldman (228:1038, 1974), I feel that a response is necessary. Firstly, Dr. Paloyan has as one of his coauthors a respected endocrinologist, Dr. Ann Lawrence. Secondly, it is well known that his concept of a very high incidence of hyperplasia in primary hyperparathyroidism is not generally accepted, but it seemed desirable to have this thesis documented in an extended monograph for study. It is interesting that during this past month two papers from major institutions with considerable experience in parathyroid surgery have accepted the notion that hyperplasia in primary hyperparathyroidism is a far more common disease than had previously been recorded (<i>Surgery</i>75:75, 1974;<i>Surg Clin N Am</i>54:443, 1974). These physicians at Lackland Air Force Base Hospital and the Cleveland Clinic have
Long-term metaproterenol therapy in asthmatic children
Authors: M. L. Brandon
Journal: JAMA (1976)

The bronchodilator efficacy and safety of metaproterenol sulfate were evaluated by double-blind crossover tests against placebo at three intervals during a 90-day treatment period in 50 asthmatic children. One group of 25 patients was continuously treated with metaproterenol syrup, and the other 25 with placebo syrup. Pulmonary function tests showed statistically significant improvements in forced expiratory volume, forced expiratory volume in one second, and peak expiratory flow rate after metaproterenol administration as compared with those measurements after treatment with placebo. Biweekly global evaluations of responses to metaproterenol administration were consistently more favorable than responses to placebo. Tachycardia and blood pressure changes after metaproterenol administration were consistent with the pharmacologic properties of beta-sympathomimetic stimulants. Side effects during metaproterenol treatment were minimal and laboratory data remained normal. (<i>JAMA</i>235:736-737, 1976)
FRIEDRICH VON RECKLINGHAUSEN (1833-1910) GERMAN PATHOLOGIST
Journal: JAMA (1968)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Thyroid Hemiagenesis
Authors: AVRAAM AVRAMIDES, APICHATI VICHAYANRAT, NATHAN SOLOMON, ANNE C. CARTER
Journal: Clinical Nuclear Medicine (1977)

Thyroid hemiagenesis is a rare benign congenital anomaly of the thyroid. Three new cases and an additional 33 cases from the world literature are reviewed. In the majority of cases, the left lobe of the thyroid was absent and the patients were euthyroid. Hypothyroidism was observed in one case and thyroid carcinoma in another case. The diagnosis is made by finding absence of a thyroid lobe in the thyroid scan, preferably taken after TSH stimulation. Unnecessary surgery for a mistaken “cold nodule” thus is avoided.
THE CURABILITY OF NASO-MUCOSITIS.
Authors: THOS. F. RUMBOLD
Journal: JAMA (1893)

(<i>Continued from page 848</i>). Part II. <i>The Number and Intervals of Local Applications will vary with the Grades.—If the Patient of the First Grade, an Infant, is Properly Treated</i>soon after it has taken cold, the disease will be of very short duration, because the reparative processes are very strong at this age. In case the patient is only a few days or weeks old, two or three applications may be required the first day; two on the second day, and one on the third. Frequent treatments are necessary, because the secretion forms rapidly and requires removal as soon as it is formed. Patients from one to twelve months of age will require daily treatments at first for from three to ten days, and then two or three weeks' treatment given every other day, making in all from nine to nineteen local applications. Those from one to two years of
Evaluation of circulating biomarkers of bone metastases in early-stage breast cancer.
Authors: Windy Marie Dean-Colomb, Kenneth R. Hess, Elliana J. Young, Terrie Gornet, Beverly Carol Handy, Stacy L. Moulder, Nuhad K. Ibrahim, Lajos Pusztai, Daniel J. Booser, Vicente Valero, Gabriel N. Hortobagyi, Francisco J. Esteva
Journal: Journal of Clinical Oncology (2012)

10 Background: Bone is the preferred site for metastases of breast cancer, affecting approximately 70% of women with advanced disease. N-terminal of procollagen type 1 (P1NP), c-terminal peptide crosslinks (CTX), osteocalcin (OC), and interleukin-6 (IL-6) are markers of bone turnover that may have clinical utility as predictors of breast cancer recurrence in the bone. Methods: Serum was collected prior to treatment from 162 patients with stage I-III and 83 patients with stage IV breast cancer from 09/2001 to 12/2008. Serum levels of P1NP, CTX, OC, and IL-6 were determined using the Roche’s Elecsys 2010 automated immunoassay system. Correlations of biomarker levels with stage and with time to bone metastases development were assessed with Cox proportional hazards regression analysis and the Kaplan-Meier method. Results: Patients with stage IV at the time of diagnosis had higher levels of serum P1NP (p&lt;0.0001) and CTX (p&lt;0.0001) compared with stage I-III patients. Fifty-five of the 162 patients with stage I-III breast cancer subsequently developed metastatic disease. Baseline P1NP level ≥ 75 ng/mL predicted time to development of bone metastases in patients with stage I-III breast cancer (hazard ratio = 2.7, 95% confidence intervals = (1.2, 6.0), p = 0.031), even after adjusting for clinical factors (p = 0.019). Baseline P1NP level also correlated with OS when it was modeled as a quadratic polynomial (on the log scale) with patients with P1NP level ≥ 75 ng/mL having a worse overall survival (hazard ratio = 3.3, 95% confidence intervals = (1.5, 7.3),p = 0.0036. Conclusions: In patients with stage I-III breast cancer, serum P1NP levels &gt;75 ng/mL prior to definitive treatment correlated with shorter time to development of bone metastases and shorter overall survival rate. Baseline serum levels of IL-6, CTX and osteocalcin did not correlate with development of bone metastases.
Incorrect Conflict of Interest Disclosure and Incorrect Author Affiliation
Journal: JAMA Internal Medicine (2017)

Peter J. Snyder, MD; David L. Kopperdahl, PhD; Alisa J. Stephens-Shields, PhD; Susan S. Ellenberg, PhD; Jane A. Cauley, DrPH; Kristine E. Ensrud, MD, MPH; Cora E. Lewis, MD, MPH; Elizabeth Barrett-Connor, MD; Ann V. Schwartz, PhD, MPH; David C. Lee, PhD; Shalender Bhasin, MD; Glenn R. Cunningham, MD; Thomas M. Gill, MD; Alvin M. Matsumoto, MD; Ronald S. Swerdloff, MD; Shehzad Basaria, MD; Susan J. Diem, MD, MPH; Christina Wang, MD; Xiaoling Hou, MS; Denise Cifelli, MS; Darlene Dougar, MPH; Bret Zeldow, MS; Douglas C. Bauer, MD; Tony M. Keaveny, PhD
American cutaneous leishmaniasis. Inefficacy of metronidazole in treatment
Authors: B. C. Walton
Journal: JAMA (1974)

American leishmaniasis, a disease limited to the American tropics and relatively unfamiliar to North American physicians, is seen in the United States with increasing frequency since the advent of air travel. In contrast to a recent report of successful treatment with metronidazole, our experience of failure in five of six cases indicates that this drug is ineffective. Unlike<i>Leishmania tropica</i>, which causes the Old World form of cutaneous leishmaniasis,<i>L braziliensis</i>can persist after disappearance of the primary ulcer and subsequently produce severely mutilating mucosal lesions. Because of this danger, complete eradication of the parasite is extremely important and, in spite of recognized disadvantages, pentavalent antimonial compounds remain the drugs of choice for this infection. (<i>JAMA</i>228:1256-1258, 1974)
Current Comment
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Increased Risk of Ischemic Stroke After Radiotherapy on the Neck in Patients Younger Than 60 Years
Authors: Lucille D.A. Dorresteijn, Arnoud C. Kappelle, Willem Boogerd, Willem J. Klokman, Alfons J.M. Balm, Ronald B. Keus, Flora E. van Leeuwen, Harry Bartelink
Journal: Journal of Clinical Oncology (2002)

To estimate the risk of ischemic stroke in patients irradiated for head and neck tumors.The incidence of ischemic stroke was determined in 367 patients with head and neck tumors (162 larynx carcinomas, 114 pleomorphic adenomas, and 91 parotid carcinomas) who had been treated with local radiotherapy (RT) at an age younger than 60 years. Relative risk (RR) of ischemic stroke was determined by comparison with population rates from a stroke-incidence register, adjusted for sex and age. Other risk factors for stroke (hypertension, smoking, hypercholesterolemia, diabetes mellitus [DM]) were registered. The median follow-up time after RT was 7.7 years (3,011 person-years of follow-up).Fourteen cases of stroke occurred (expected, 2.5; RR, 5.6; 95% confidence interval [CI], 3.1 to 9.4): eight in patients with laryngeal carcinoma (expected,1.56; RR, 5.1; 95% CI, 2.2 to 10.1), four in pleomorphic adenoma patients (expected, 0.71; RR, 5.7; 95% CI, 1.5 to 14.5), and two in parotid carcinoma patients (expected, 0.24; RR, 8.5, 95% CI, 1.0 to 30.6). Five of six strokes in patients irradiated for a parotid tumor occurred at the ipsilateral side. Analysis of other risk factors for cerebrovascular disease showed hypertension and DM to cause an increase of the RR after RT. After more than 10 years' follow-up, the RR was 10.1 (95% CI, 4.4 to 20.0). The 15-year cumulative risk of stroke after RT on the neck was 12.0% (95% CI, 6.5% to 21.4%).This is the first study to demonstrate an increased risk of stroke after RT on the neck. During medical follow-up, preventive measures should be taken to reduce the impact of the risk factors for cerebrovascular disease, to decrease stroke in these patients.
A Preliminary Fifth Year in the Medical Curriculum.
Journal: JAMA (1904)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Anomale Kinder.
Journal: JAMA (1923)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Safety of Testosterone Replacement Therapy
Journal: JAMA (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Update: chenodeoxycholic acid and gallstones
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
O método de Meduna em esquizofrênicos crônicos
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Incorrect Date.
Journal: JAMA (1996)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Collaborative research networks work
Authors: Anamaria A. Camargo, Andrew J.G. Simpson
Journal: Journal of Clinical Investigation (2003)

Brazil was heralded for completion of the first genome sequence of a plant pathogen following the development of a virtual research center — a collaborative network of laboratories throughout the state of São Paulo, drawing on the expertise of a dispersed and diverse scientific community and on investment from both the government and the private sector. Strategies key to the success of this model are discussed here in the context of continuing collaborative scientific endeavors in both developed and developing countries.
Anesthesiology
Authors: Ellison C. Pierce
Journal: JAMA (1985)

Reduction of anesthesia morbidity and mortality is a subject of major interest among anesthesiologists, and current research efforts address this problem in a number of ways. Investigators have shown that in high-risk and/or elderly patients, utilization of state-of-the-art preoperative, intraoperative, and postoperative hemodynamic and other physiologic monitoring, plus pharmacologic intervention, results in reduced morbidity and mortality associated with anesthesia and surgery. Rao et al<sup>3</sup>examined myocardial reinfarction rates in two groups of patients undergoing noncardiac surgery. The first group was studied retrospectively from 1973 to 1976, and the second prospectively from 1977 through 1982. The latter had the advantages of "newer invasive monitoring in the preoperative period, which guided the titration of pharmacologic therapy to achieve the best possible physical status... and had the benefit of the new cardioactive and vasoactive drugs." The overall rate of reinfarction fell from 7.7% in the first group (in line with many other