tbuckley/cabot-search huggingface dataset:
Miracles in medicine and problems in pedagogy
Authors: S. M. Mellinkoff
Journal: JAMA (1966)

The story of Naaman, "captain of the Host of the King of Syria," is of timeless significance in medicine. Considered to be a leper, Naaman was believed doomed. His wife, at the urging of her maid, who had been taken captive in Israel by the Syrians, persuaded Naaman to ask Elisha, a prophet in Samaria, to "recover him of his leprosy." "... So Naaman came with his horses and chariot and stood at the door of the house of Elisha." But Elisha did not come out to see him and lay his hand on the sore places and call on the Lord for a cure. Instead he sent a messenger to tell Naaman, "Go and wash in the Jordan seven times, and thy flesh shall come again to thee, and thou shalt be clean." "Naaman turned and went away in a rage. And his servants came near and spake unto him....
THE MEDICAL PROFESSION ORGANIZING.
Journal: JAMA (1901)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Highlights
Authors: Rebecca Thurston, Nancy Keating
Journal: JAMA (2019)

A Dietary Intervention for Nonalcoholic Fatty Liver Disease 256Treatment guidelines do not recommend a specifi c diet for children with nonalcoholic fatty liver disease.In a randomized trial that enrolled 40 male adolescents aged 11 to 16 years with histologically diagnosed nonalcoholic fatty liver disease, Schwimmer and colleagues found that a diet low in free sugar content decreased hepatic steatosis.
Metabolic Studies on Effects of Spironolactone
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Healthy Environments for Healthy People: Bioremediation Today and Tomorrow
Authors: Celia Bonaventura, Franklin M. Johnson
Journal: Environmental Health Perspectives (1997)

Increases in environmental contamination lead to a progressive deterioration of environmental quality.This condition challenges our global society to find effective measures of remediation to reverse the negative conditions that severely threaten human and environmental health.We discuss the progress being made toward this goal through application of bioremediation techniques.Bioremediation generally utilizes microbes (bacteria, fungi, yeast, and algae), although higher plants are used in some applications.New bioremediation approaches are emerging based on advances in molecular biology and process engineering.Bioremediation continues to be the favored approach for processing biological wastes and avoiding microbial pathogenesis.Bioremediation may also play an increasing role in concentrating metals and radioactive materials to avoid toxicity or to recover metals for reuse.Microbes can biodegrade organic chemicals; purposeful enhancement of this natural process can aid in pollutant degradation and waste-site cleanup operations.Recently developed rapid-screening assays can identify organisms capable of degrading specific wastes and new gene-probe methods can ascertain their abundance at specific sites.New tools and techniques for use of bioremediation in situ, in biofilters, and in bioreactors are contributing to the rapid growth of this field.Bioremediation has already proven itself to be a cost-effective and beneficial addition to chemical and physical methods of managing wastes and environmental pollutants.We anticipate that it will play an increasingly important role as a result of new and emerging techniques and processes.
Media
Authors: G. Timothy Johnson
Journal: JAMA (1987)

The revolution that has transformed medical practice since World War II from a personalized relationship between patient and physician into a health industry has been accompanied by a revolution in the relationship between the worlds of medicine and the media. Back in what many call "the good old days," the two worlds largely ignored each other. Medical information was regarded as the province of physicians, to be parceled out to patients as they felt was useful and appropriate. The media usually regarded physicians with distant respect, and they, in turn, often treated the media with polite disdain. Times have changed! Physicians' lives are, today, unavoidably affected by the media. Moreover, each courts the other in a manner that both might acknowledge as self-serving. At the very least, physicians must live with the portrayal of themselves in entertainment formats; such portraits may raise expectations to unrealistic heights of perfection or plunge
Tissue inhibitor of metalloproteinase-1 messenger RNA expression is enhanced relative to interstitial collagenase messenger RNA in experimental liver injury and fibrosis
Authors: J Iredale
Journal: Hepatology (1996)

Liver fibrosis results from a relative imbalance between synthesis and degradation of matrix proteins. We have previously described release of the protein collagenase inhibitor, tissue inhibitor of metalloproteinase-1 (TIMP-1), by culture-activated human hepatic stellate cells (HSCs). In this study, we have investigated the relative expression of TIMP-1 and interstitial collagenase in culture-activated rat HSCs and rat models of liver injury and fibrosis. The complementary DNA (cDNA) for rat TIMP-1 was obtained by homology polymerase chain reaction (PCR) and sequenced. By Northern analysis using this probe, TIMP-1 messenger RNA (mRNA) expression was up-regulated with HSC activation by culture on plastic as defined by cellular expression of procollagen-1. Interstitial collagenase mRNA was expressed in early 1. Interstitial collagenase mRNA was expressed in early culture (<4 days) but became undetectable in more activated cells (7-21 days). By activity assay of serum-free cell-conditioned media, TIMP-1 was found to be released in increasingly concentrations with duration of culture on plastic. Expression of TIMP-1 interstitial collagenase, and procollagen-1 mRNAs were studied in rat models of biliary and parenchymal injury (bile duct ligation and CC14 administration) by ribonuclease protein assay. TIMP-1 mRNA expression was increased at 6, 24 hours, and 3 days after bile duct ligation and was also shown to rise in acute CC14 liver injury and remain elevated as the liver became fibrotic. TIMP-1 expression preceded procollagen-1 expression in both models. In contrasts, interstitial collagenase mRNA levels remained similar to control values throughout both models of liver injury. Total cellular RNA from hepatocytes, HSCs, and kupffer cells freshly isolated from livers after acute CC14 injury was subjected to Northern analysis. TIMP-1 transcripts were observed in nonparenchymal cells only. We suggest that increased expression of TIMP-1 relative to interstitial collagenase by HSCs may promote progression of liver fibrosis in these rat models by preventing degradation of secreted collagens.
Angiography in Renal Trauma
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Sulfinpyrazone in the Prevention of Sudden Death after Myocardial Infarction
Journal: New England Journal of Medicine (1980)

We report the results of a randomized double-blind, multicenter trial comparing sulfinpyrazone (200 mg four times a day) and a placebo in the prevention of cardiac mortality among 1558 patients followed for an average of 16 months, beginning 25 to 35 days after a documented myocardial infarction. All but one of the 106 deaths in the group were cardiac; 59 were sudden. The reduction in cardiac mortality at 24 months in the sulfinpyrazone group was 32 per cent (P = 0.058), and the reduction in sudden death was 43 per cent (P = 0.041). The benefit of sulfinpyrazone was attributable entirely to a reduction in sudden death during the second through seventh months after infarction, when there were 35 cardiac deaths in the placebo group and 17 in the sulfinpyrazone group (P = 0.021); of these deaths, 24 in the placebo group and six in the sulfinpyrazone group were sudden cardiac deaths -- a sulfinpyrazone-induced 74 per cent reduction in the calculated mortality rate (P = 0.003). We conclude that sulfinpyrazone prevents sudden cardiac death during the high-risk period shortly after an acute myocardial infarction, but that there is no further apparent effect beyond the seventh month after infarction.
Corporal Punishment
Authors: R. Armstrong-Jones
Journal: BMJ (1938)

was rapid, an agranulocytosis might have developed in this case.The patient did his normal work and had no complaints, and only a mild degree of cyanosis.This case leads me to suggest that white cell counts in patients under treatment with sulphanilamide might well be under- taken as a routine so that some indication may be given of possible toxic effects before rather than after the event.-I am, etc., Batavia, Dutch East Indies, April 5.
An Activated ErbB3/NRG1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells
Authors: Qing Sheng, Xinggang Liu, Eleanor Fleming, Karen Yuan, Huiying Piao, Jinyun Chen, Zeinab Moustafa, Roman K. Thomas, Heidi Greulich, Anna Schinzel, Sara Zaghlul, David Batt, Seth Ettenberg, Matthew Meyerson, Birgit Schoeber Andrew L. Kung, William C. Hahn, Ronny Drapkin, David M. Livingston, Joyce F. Liu
Journal: Cancer Cell (2010)
Trompa de Falopio, esterilidad de causa tubaria y asuntos conexos
Journal: JAMA (1952)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Abstract 2406: Comparison Of Invasive Procedures And Medical Treatment In Patients With ST-segment Elevation Myocardial Infarction: Impact Of Initial Admission To Hospitals With Versus Without Catheterization Laboratory. Results From The German ACOS Registry.
Authors: Alexandros Skarlos, Anselm K Gitt, Claus Juenger, Harm Wienbergen, Ralf Zahn, Jochen Senges, Uwe Zeymer
Journal: Circulation (2007)

Introduction: The aim of this analysis was to evaluate the rate of invasive and revascularization procedures and adherence to guideline recommended therapies in patients with STEMI initially admitted to hospitals with and without catheterization laboratory in clinical practice. Methods: Between 07/2000 and 12/2002 16817 patients with an acute coronary syndrome from 154 hospitals have been included in the ACOS registry. 8303 of these patients presented with ST-segment elevation myocardial infarction. 6351 patients (76,5%) were initially admitted to a hospital with catheterization laboratory, 1952 (23,5%) in a hospital without catheterization laboratory. Results: We observed significant differences for treatment during the first 48h and revascularization procedures (table ). In the univariate analysis the total in-hospital and 1-year mortality was significantly lower in patients with initial admission to hospitals with catheterization laboratory (8.8% vs. 11.5%, p&lt;0.001 and 13.7% vs. 19.9%, p&lt;0.0001). However, this was statistically significant after adjustment for age, gender, history of myocardial infarction, diabetes, renal insufficiency, heart rate &lt; 100/min and systolic blood pressure &gt; 100 mmHg for 1-year-mortality only (Odds ratio 0.75; 95% CI 0.65 – 0.88) and not for in-hospital mortality (Odds ratio 0.91; 95% CI 0.76 – 1.10). Conclusions: In clinical practice patients with STEMI admitted to hospitals with catheterization laboratory are treated with significantly higher rates of reperfusion and guideline recommended adjunctive therapies. This is associated with a lower 1-year mortality.
Human immunodeficiency virus antigenemia
Authors: J. P. Phair
Journal: JAMA (1987)

The article by Kessler et al<sup>1</sup>in this issue ofThe Journaldescribes the acute illness associated with human immunodeficiency virus (HIV) infection in four individuals. Of interest was the detection of HIV antigenemia during the course of this self-limited illness before enzyme-linked immunosorbent and Western blot assays for antibody to HIV became positive. The presence of circulating antigen thus helped to establish the diagnosis. Other investigators<sup>2</sup>have reported that HIV antigenemia precedes seroconversion in an unknown proportion of acutely infected individuals. The evidence available to date suggests that the circulating antigen contains the core protein of the HIV (p24) and possibly other epitopes of the virus, and that when antibody to the p24 component of the virus increases to measurable concentrations in serum or plasma, the antigen can no longer be detected.<sup>3</sup>In some individuals, months to years after infection, anti-p24 concentrations fall in association with
Hormonal relationships during the menstrual cycle
Authors: S. S. Yen
Journal: JAMA (1970)

Physiologic fluctuation of follicle-stimulating hormone (FSH), luteinizing hormone (LH), human-growth hormone (HGH), and progesterone concentrations in serum samples of women with ovulatory menstrual cycles were determined by radioimmunoassay and protein-binding assay. During the follicular phase of the cycle, the tonic secretion of FSH showed an initial rise followed by a progressive fall toward the midcycle. In contrast, LH secretion showed a steady increase. A clear elevation of progesterone concentration was observed 48 hours after the onset of a simultaneous surge of LH and FSH at midcycle. Progesterone levels rose rapidly reaching maximal concentration (mean 12.2 mμg/ml) five days after LH surge and remained elevated for five to six days. Thereafter, progesterone levels fell rapidly to an undetectable level on the day after onset of menstruation. This was accompanied by a significant elevation of the FSH and LH levels from their low concentration observed during the late luteal phase. Human-growth hormone levels observed while the patient was in a fasting, ambulant state showed a progressive rise reaching a peak just prior to LH surge and there was a random fluctuation during luteal phase of the cycle.
ASTHMA AND ALLERGY
Journal: JAMA (1927)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The Improved Prophylactic Method in the Treatment of Eclampsia.
Journal: JAMA (1930)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Obituary Listing
Journal: JAMA (1998)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
From the Centers for Disease Control. Surgeon General's Workshop on Health Promotion and Aging: summary recommendations of the Medication Working Group
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal