tbuckley/cabot-search huggingface dataset:
Efficacy of immune-checkpoint inhibitors (ICI) in non-small cell lung cancer (NSCLC) patients harboring activating molecular alterations (ImmunoTarget).
Authors: Julien Mazieres, Alexander E. Drilon, Laurent Mhanna, Julie Milia, Amellie Lusque, Alexis B. Cortot, Laura Mezquita, Alesha Thai, Sebastien Couraud, Remi Veillon, Celine Mascaux, Robert Schouten, Joel W. Neal, Terry L. Ng, Martin Frueh, Nir Peled, Valerie Gounant, Sanjay Popat, Viola Weijia Zhu, Oliver Gautschi
Journal: Journal of Clinical Oncology (2018)

9010 Background: Data on ICI activity in patients with oncogenic driver are limited. The aim of this study was to collect further data across various molecular subgroups. Methods: We conducted a retrospective multicenter study of patients receiving ICI for stage IV NSCLC with genomic alterations. Anonymized data were evaluated for clinicopathologic characteristics and outcomes: best response (RECIST v1.1), progression-free survival (PFS) and overall survival (OS) from ICI initiation. Results: We included 527 patients treated in 25 centers The. Molecular alterations involved KRAS (n = 252), EGFR (n = 110), BRAF (n = 38), MET (n = 36), HER2 (n = 23), ALK (n = 18), RET (n = 14), ROS1 (n = 5), and multiple drivers (n = 31). Median age was 60 years, sex-ratio was 1:1, never/former/current smokers were 27/51/22%, and the majority of tumors were adenocarcinoma. ICIs were mainly anti-PD1 (92%) given in the first (5%), second (42%), third (26%), or later line (27%) settings. The best response rate was 19% [15-22%]. The median PFS and OS were 2.8 [2.5-3.1] and 13.3 [9.8-14.8] months, respectively. Outcomes by molecular subtypes are reported below (table 1). EGFR-mutant had shorter PFS compared to KRAS-mutant (p < 0.001). T790M mutation was associated with a shorter PFS than other EGFR mutations (p = 0.0001) whereas the benefit was the same across all KRAS mutation subtypes. Among MET alterations, exon 14 mutations were the most sensitive to ICI. PFS was positively influenced by smoking (p = 0.003) and PDL1 expression (p = 0.02) in the overall population but not for EGFR-mutant. Conclusions: ICI has inconstant efficacy in NSCLC harboring activating mutation. KRAS, BRAF and MET-exon 14 patients derive a greater benefit than EGFR, ALK and RET patients. Driver n Best response (%) PFS OS CR/PR SD PD Median (months*) 6 m PFS (%) 1 y PFS (%) Median (months*) BRAF 38 28.1 28.1 43.8 3.0 35 19 13.6 KRAS 252 27.2 23.1 49.8 3.2 39 26 13.5 ROS1 5 20 0 80 NA NA NA NA MET 36 15.6 34.4 50.0 3.4 33 23 18.4 EGFR 110 11.0 18.0 71.0 2.0 16 6 8.8 HER2 23 9.5 28.6 61.9 3.5 34 17 10.0 RET 14 7.1 21.4 71.4 2.2 16 8 6.5 ALK 18 0 21.4 78.6 2.1 16 8 17.0 *: from ICI initiation. CR/PR : Complete/Partial response, SD/PD Stable/Progressive disease.
Session A: Breast Cancer (Abstract Nos. A1-A56)
Authors: D Traisci, P Di, M Leva, M Lombardo, D Lombardi, S Spazzapan, A Buonadonna, S Scalone, M Zanetti, A Freschi, D Magri, A Crivellari, V Lauro, N Mura, M Ionta, A Carta, D Vacca, D Nonnis, S Deplano, A Farris, A Contu, V Lorusso, S Palmeri, B Massidda, G Gherardi, A Croce, A Ferrari, S Perrone, F Silva, V Gandolfi, A Scanni, A Bertolini, A Muffatti, N Verde, M Fiumanò, O Fusco, M Giordano, K Borgonovo, V Filipazzi, A Gambaro, G Scognamiglio, A Fasolo, L Sacco, S Anna, R Formato, R Iaffaioli, A Tortoriello, S Prete, M Caraglia, A Pisano, F Fanelli, G Ianniello, S Quattrin, S Cigolari, G Cartenì, C Pizza, O Marano, G Pezzella, T Pedicini, A Febbraro, P Incoronato, L Manzione, E Ferrari, N Marzano, G Giotta, G Colucci, Int Pascale, G Turitto, E Barletta, C Pisano, A Ottaiano, G Bruni, R Tambaro, A Naples
Journal: Annals of Oncology (2003)
Adding abiraterone for men with high-risk prostate cancer (PCa) starting long-term androgen deprivation therapy (ADT): Survival results from STAMPEDE (NCT00268476).
Authors: Nicholas D. James, Johann S. De Bono, Melissa Ruth Spears, Noel Clarke, Malcolm David Mason, David P. Dearnaley, Alastair W S Ritchie, J. Martin Russell, Clare Gilson, Robert J. Jones, Silke Gillessen, David Matheson, San Aung, Alison J. Birtle, Simon Chowdhury, Joanna Gale, Zafar Malik, Joe M. O'Sullivan, Mahesh K B Parmar, Matthew Robert Sydes
Journal: Journal of Clinical Oncology (2017)

LBA5003 The full, final text of this abstract will be available at abstracts.asco.org at 7:30 AM (EDT) on Saturday, June 3, 2017, and in the Annual Meeting Proceedings online supplement to the June 20, 2017, issue of the Journal of Clinical Oncology. Onsite at the Meeting, this abstract will be printed in the Saturday edition of ASCO Daily News.
TETANY
Journal: JAMA (1920)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
头颈部光化性角化病 4 种治疗方法的成本‐效益研究
Journal: British Journal of Dermatology (2020)

光化性角化病 (AK) 是一种受阳光损伤的皮肤区域（病变），主要发现于身体暴露在阳光下的部位。如果不进行治疗，存在很小的风险，AK 有可能进展为一种称为皮肤鳞状细胞癌的角质形成细胞癌（也称为非黑色素瘤皮肤癌）。
Anticoagulants
Authors: Douglas S. Riggs
Journal: New England Journal of Medicine (1950)

DicumarolIn 1922 Schofield44 described a hemorrhagic disease in cattle fed spoiled sweet-clover hay. Roderick45 found that the basic defect in sweet-clover disease was prothrombin deficiency and that the hemorrhagic tendency could be controlled by a withdrawal of the diet of spoiled hay and transfusion of fresh blood from healthy cattle. In 1934 Link and his collaborators at the University of Wisconsin Agricultural Experiment Station initiated an intensive search for the causative agent in spoiled sweet clover. By 1940 the active principle had been isolated in crystalline form,46 and shortly thereafter it was identified by synthesis as 3,3′-methylenebis (4-hydroxycoumarin), now known . . .
Saunders' Pocket Medical Formulary, with an Appendix, Containing Posological Table: Formulas and Doses for Hypodermic Medication; Poisons and their Antidotes; etc.
Journal: JAMA (1907)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Marriages
Journal: JAMA (1935)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Indications and contraindications for exercise testing
Journal: JAMA (1981)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Retrograde Colonoscopy
Authors: J. Fox
Journal: Endoscopy (1969)

Intubation of the colon is advised as a preliminary to colonoscopy. Retrograde colonoscopy should therefore be preceded by transanal introduction of a “colon tube” under radiological control. Multiple suction biopsies using the Quinton tube can be alternated with colonoscopy through the “colon tube” without further discomfort to the patient.
JFK's death—the plain truth from the MDs who did the autopsy
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
"AMERICAN MEDICAL JURISPRUDENCE AND THE EXPERT WITNESS"
Journal: JAMA (1922)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Statistical Methods for Censored Survival Data
Authors: Norman Breslow
Journal: Environmental Health Perspectives (1979)

Methods of statistical analysis of censored survival times are briefly reviewed and illustrated by application to clinical trials data. These include estimation of the survival curce, nonparametric tests to compare several survival curves, tests for trend, and regression analysis. Extensions of the methodology are made for application to epidemiologic case-control studies. These are used to estimate relative risks for leukemia associated with radiation exposures. A final section provides some annotated references to the recent literature.
Current cancer concepts. What is the rationale for an extended radical procedure in early cases?
Authors: J. A. Urban
Journal: JAMA (1967)

Primary treatment of breast cancer succeeds when the primary tumor and its regional lymph node spread are completely extirpated or destroyed in the absence of established systemic metastases. The classical radical mastectomy has been extended to include en bloc in continuity excision of the internal mammary lymph node chain. This procedure removes the primary breast cancer in continuity with both of its primary lymph node deposits, axillary as well as internal mammary, and should result in better local control and an improved salvage rate. The patients most likely to benefit from this extended procedure are those with a high risk of internal mammary node metastases. Stage I carcinoma of the breast is defined as an early lesion confined to the breast, with no clinically suspicious axillary lymph nodes and no distant metastases suspected. Not infrequently, pathologic examination of the operative specimen will disclose metastatic axillary nodes in some clinical stage
Sexual misconduct in the practice of medicine. Council on Ethical and Judicial Affairs, American Medical Association
Authors: Richard J. McMurray, Oscar W. Clarke, John A. Barrasso, Dexanne B. Clohan, Charles H. Epps, John Glasson, Robert McQuillan, Charles W. Plows, Michael A. Puzak, David Orentlicher, Kristen A. Halkola
Journal: JAMA (1991)

The American Medical Association's Council on Ethical and Judicial Affairs recently reviewed the ethical implications of sexual or romantic relationships between physicians and patients. The Council has concluded that (1) sexual contact or a romantic relationship concurrent with the physician-patient relationship is unethical; (2) sexual contact or a romantic relationship with a former patient may be unethical under certain circumstances; (3) education on the ethical issues involved in sexual misconduct should be included throughout all levels of medical training; and (4) in the case of sexual misconduct, reporting offending colleagues is especially important.
Misspelled Term
Journal: JAMA (1989)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
In this issue
Authors: Ezzie Hutchinson, Kristine Novak, Nicola Mccarthy, Louisa Flintoft, Oliver Childs, Claudia Bentley, Emma Green, Art Controller, Nicola Hawes, Susanne Harris, Judith Shadwell, Deputy Production, Simon Fenwick, Luisa Estanislao, Sam Arr-Jones, Sheryl Ocampo, Amanda Ward, Catherine Alexander, Mark Jones, Puja Kamdar, Christina Large, Annette Thomas, Peter Collins, Hugh Blackbourn, Jenny Henderson, Tony Rudland, Philip Campbell, Fabien Savenay, Anna Duguid, Donna Colbourne, James Mcquat, Yvonne Strong, Kelly Hopkins, Jocelyn Hilton
Journal: Nature reviews. Cancer (2004)
Monitoring Exposure to Atomic Bomb Radiation by Somatic Mutation
Authors: Mitoshi Akiyama, Seishi Kyoizumi, Yoichiro Kusunoki, Yuko Hirai, Kazumi Tanabe, John B. Cologne
Journal: Environmental Health Perspectives (1996)

Atomic bomb survivors are a population suitable for studying the relationship between somatic mutation and cancer risk because their exposure doses are relatively well known and their dose responses in terms of cancer risk have also been thoroughly studied.An analysis has been made of erythrocyte glycophorin A (GPA) gene mutations in 1,226 atomic bomb survivors in Hiroshima and Nagasaki.The GPA mutation frequency (Mf) increased slightly but significantly with age at the time of measurement and with the number of cigarettes smoked.After adjustment for the effect of smoking, the Mf was significantly higher in males than in females and higher in Hiroshima than in Nagasaki.All of these characteristics of the background GPA Mf were in accord with those of solid tumor incidence obtained from an earlier epidemiological study of A-bomb sur- vivors.Analysis of the dose effect on Mf revealed the doubling dose to be about 1.20 Sv and the minimum dose for detection of a significant increase to be about 0.24 Sv.No significant dose effect for difference in sex, city, or age at the time of bombing was observed.Interestingly, the doubling dose for the GPA Mf approximated that for solid cancer incidence (1.59 Sv).And the minimum dose for detection was not inconsistent with the data for solid cancer incidence.The dose effect was significantly higher in those diagnosed with cancer before or after measurement than in those without a history of cancer.These findings are consistent with the hypothesis that somatic mutations are the main cause of excess cancer risk from radiation exposure.
Pencillin prophylaxis.
Authors: G Gover, M G Wright, J D Langdon
Journal: BMJ (1971)

compensated neurotic taking a small dose of amphetamine to a highly distressed human being making excessive demands on an already busy Eervice.In my view there is a strong case to be made for excluding patients who have been on amphetamines for several years from the current witch hunt, although I agree that no neurotics should be started on the drug at this point in time.-I am, etc.,
Green's Pathology and Morbid Anatomy. Pathology and Morbid Anatomy
Journal: JAMA (1895)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MORTALITY PHENOMENA IN THE PHILIPPINES
Journal: JAMA (1918)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Journals JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2024 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal