tbuckley/cabot-search huggingface dataset:
Hysterie.
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Vigorous physical activity, cardiorespiratory fitness and a diet low in saturated relative to polyunsaturated fat may protect against development of the metabolic syndrome in middle-aged men.
Authors: David E. Laaksonen, Timo A. Lakka, Hanna-Maaria Lakka, Kristiina Nyyssonen, Leo K. Niskanen, Rainer Rauramaa, George A. Kaplan, Jukka T. Salonen
Journal: Circulation (2001)

0012 Few studies have prospectively addressed the role of physical activity, fitness and dietary fat type in the development of the metabolic syndrome (MS), a condition that markedly increases the risk for diabetes and cardiovascular disease. We examined the development of MS in 453 normoglycemic men participating in the Kuopio Ischemic Heart Disease Risk Factor Study who had no more than 2 features of MS at baseline. Leisure-time physical activity for the preceding 12 mo was measured at baseline with a validated questionnaire. Maximum oxygen uptake was measured directly during an exercise stress test. Long-term dietary fat composition was estimated from lipid-standardized proportions of saturated and polyunsaturated fatty acids measured from fasting whole serum. After 4 y 145 men had developed 3 or more features of MS as defined by the presence of impaired fasting glucose or diabetes (fasting blood glucose ≥5.6 mM), overweight or obesity (BMI ≥27 kg/m 2 ), waist-hip ratio ≥0.90, hypertension (blood pressure ≥140/90) or dyslipidemia (serum triglycerides ≥1.7 mM or HDL &lt;0.9 mM). In logistic regression analyses adjusting for confounding factors, the serum palmitate proportion (OR 2.7, 95%CI 1.4-5.1 for upper vs lower third) and palmitate/linoleate ratio (OR 2.3, 95%CI 1.2-4.4 for upper vs lower third) was positively and the α-linolenate proportion (OR 0.44, 95%CI 0.23-0.84) negatively associated with development of MS. The serum linoleate proportion tended to protect against development of MS (OR 0.55, 95%CI 0.28-1.04). Cardiorespiratory fitness (OR 0.37, 95%CI 0.28-0.97 for highest vs lowest fourth) and at least 20 min vigorous exercise/wk (OR 0.53, 95%CI 0.28-1.00) protected against development of MS independently of confounding factors. Although genetic and other factors may also play a role, these findings underscore the importance of dietary fat modification and physical exercise for primary prevention of the metabolic syndrome and its consequences even in apparently low-risk middle-aged men.
KEROSENE POISONING
Authors: Orville Barbour
Journal: JAMA (1926)

During the last six years I have seen four cases of kerosene poisoning. One of the children died within a few minutes after medical aid was summoned, and no laboratory data could be obtained. However, a noticeable feature of the case was the bright cherry red color of the lips. This persisted until after death. Two of the patients did not get enough kerosene to cause any alarming symptoms. As I had access to laboratory and hospital facilities with the fourth case, I made an attempt to obtain some definite information on this condition. <h3>REPORT OF CASE</h3> A white boy, aged 15 months, admitted to the Methodist Hospital at 4 p. m., May 24, 1926, had drunk a portion of 6 ounces of kerosene, six hours previously. As the cup was tipped over when he was found, it was impossible to determine just how much he had swallowed.
Spontaneous peritonitis and systemic lupus erythematosus. Importance of accurate diagnosis of gram-positive bacterial infections
Authors: P. E. Lipsky
Journal: JAMA (1975)

Primary Gram-positive bacterial peritonitis developed in three patients with systemic lupus erythematosus (SLE). These cases suggest a possible association between these two entities. Furthermore, they emphasize the importance of accurate diagnosis when evaluating abdominal symptoms in patients with SLE. (<i>JAMA</i>232:929-931, 1975)
Bleeding manifestations in 100 patients with amyloidosis
Authors: R. A. Yood
Journal: JAMA (1983)

Focal or generalized hemorrhage is a commonly encountered clinical problem in patients with amyloidosis. In 100 patients with amyloidosis, 41 patients experienced one or more bleeding episodes: petechiae and ecchymoses (23), gastrointestinal tract bleeding (18), bleeding after a diagnostic procedure (eight), hematuria (three), hemoptysis (two), and miscellaneous (four). Severe hemorrhage was the cause of death in three patients. Bleeding occurred frequently in the absence of abnormalities of clotting tests, suggesting that hemorrhage in amyloidosis is most often due to amyloid infiltration of blood vessels. In this group of patients, an isolated factor X deficiency was not observed. (<i>JAMA</i>1983;249:1322-1324)
Nervous System Protein Isolated in Vertebrates
Journal: JAMA (1965)

A protein that apparently resides only in the nervous system has been isolated in 30 species of vertebrates, including man. Studies currently are underway to determine the precise location and biochemical function of the socalled "S-100" protein, according to Blake W. Moore, PhD, research assistant professor of psychiatry, Washington University School of Medicine, St. Louis. "It looks as if this acidic protein may be one of a whole family specific to the nervous system," Dr. Moore told<i>JAMA</i>Medical News. "We are interested in finding out not only what and where these proteins are but, in the future, whether imbalances of them might be related to nervous system disorders." At this point, however, the investigation is much more basic. The protein was dubbed "S-100" because it is soluble in saturated ammonium sulfate, and becomes a supernatant from a 100% fraction. The S-100 has been isolated from the nervous systems of
Organ transplant improvements, demands draw increasing attention
Journal: JAMA (1984)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Book Review A Doctor Without a Country . By Thomas A. Lambie, M.D., Sc.D., F.R.G.S., with an introduction by Howard A. Kelly, M.D., F.A.C.S., LL.D. 8°, cloth, 252 pp., with 6 illustrations. New York: Fleming H. Revell Co., 1939. $2.00.
Journal: New England Journal of Medicine (1940)
Patterns of care according to treatment intent for metastatic colorectal cancer (mCRC): A two-year review of routine practice.
Authors: Kathryn Maree Field, Jayesh Desai, Jeanne Tie, Suzanne Kosmider, Susie Bae, Joseph James McKendrick, Michael Harold, Peter Gibbs
Journal: Journal of Clinical Oncology (2012)

682 Background: Cure is potentially achievable in select patients (pts) with mCRC with limited metastatic disease to liver and/or lung. To date the peri-operative strategies undertaken by oncologists in routine practice for such pts have not been well documented. Methods: A clinical database recording information on all pts diagnosed with mCRC since July 2009 from 5 hospitals was analysed. Management strategies where a curative-intent resection had occurred; was planned; or was a potential option were compared with those managed with palliative intent. Results: Status at the time of first review regarding systemic chemotherapy (CT) was documented for 280 pts. 11 (4%) had already undergone curative-intent resection; 31 (11%) had a resection planned; 27 (10%) were considered potentially resectable if their response to treatment was good; and 207 (74%) were treated with palliative intent. No pts already resected or planned for resection were &gt;ECOG 1, compared with 11% (3/27) potentially resectable and 17% (36/207) palliative pts. CT was delivered in 9 (82%) already-resected, 26 (84%) planned for resection, 26 (96%) potentially-resectable and 159 (77%) palliative-intent pts. Combination CT was the dominant strategy, although 7 of 11 (66%) already-resected pts received single agent treatment. No already-resected pts received bevacizumab with CT, compared with 27% (n=14) of planned or potentially-curative pts and 55% (n=88) of those treated with palliative intent. At the time of analysis 13 pts (42%) with a planned resection and 8 (30%) considered potentially curative have had surgery, while 3 (1.4%) where treatment was initially considered palliative have had curative-intent surgery. Conclusions: Treatment strategies for pts with mCRC differ significantly based on the treatment intent, and may be affected by surgical preference and referral pattern. Bevacizumab was less likely to be used for already-resected pts and the use of single agent therapy in this group was also not uncommon. Many pts initially considered resectable do not ultimately undergo resection, whereas occasional ‘palliative’ pts may become resectable, confirming the importance of continued consideration of this option.
Dr. J. C. Boileau grant. Anatomist extraordinaire
Authors: E. K. Sauerland
Journal: JAMA (1975)

THE VISITOR approached the modern building at the University of Toronto. A large bronze sign caught his attention: "The Discovery of Insulin 1921." Here, Banting and Best announced their dramatic discovery. This medical complex invariably was a stimulating environment. Many scientists, like the renowned pathologist Dr. William Boyd, wrote books of immense impact. Entering the Anatomy Department, the visitor strolled along the basement corridor stopping by a name plate on the door. It read, "Dr. J. C. B. Grant." Once inside, he had the strange impression that Dr. Grant simply left for lunch, temporarily interrupting his work. Grant's white coat was casually thrown over a chair. His teapot and a box of favorite biscuits stood on a shelf. A partly dissected anatomical specimen—several cervical vertebrae, the joint capsules neatly prepared, reposed on a working table. Nearby lay a scalpel, forceps, scissors, probe, and magnifying glass. Obviously, the work of the
Cigarette consumption and biochemical measures of smoke intake.
Journal: BMJ (1982)

Comparison of data contained in hospital notes and in hospital activity analysis Not entered Not entered Correctly in diagnoses/ in diagnoses/ entered in Correctly No of operations operations summary entered in operations Operation Total section of section of but not summary coded summary and summary but correctly and coded correctly not coded correctly coded coded correctly Resection of colon, rectum, or both 50 14 (28%o) 33 (66°U) 1 (0 5%) 2 (4 0) 35 (70%0) Splenectomy 30 0 24 (80/',) 0 6 (20"0) 30 (100%o)
Deaths
Journal: JAMA (1929)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
MYOCARDOSIS
Authors: ALBERT S. HYMAN
Journal: JAMA (1930)

The past twenty-five years has witnessed a remarkable change in the conception of cardiovascular disorders; from the beginning of the twentieth century, each year has added some new and important facts to the sum total of the knowledge of this group of conditions. New instruments, new procedures, new methods of examination have all contributed to this advance. Into the phraseology of medicine during this time have crept terms which formerly were unnecessary and unheard of, but with the widespread application of methods that previously were exclusively of laboratory and academic importance the vocabulary of the physician has been considerably enriched. At the same time, however, the concepts of the older clinicians have not been entirely abandoned; traditional thought is not easily relinquished. In no instance is this more true than in the fundamental medical sciences. Even a casual inspection of a modern medical dictionary will serve to impress the reader
Cholesteremia in pregnant Masai women
Authors: G. V. Mann
Journal: JAMA (1966)

Masai women did not show hypercholesteremia during the third trimester of pregnancy despite their customary diet which is rich in animal fat and protein. The data suggest that diet fat is not an important determinant of cholesteremia in pregnancy, unless the high quality of the animal protein diet or a high degree of physical fitness is an overriding protection.
Nephrology
Authors: Shaul G. Massry
Journal: JAMA (1991)

Research directed at further understanding the factors that contribute to the progression of renal failure dominates the field of nephrology.<sup>1</sup>Major advances have occurred, and it has become well accepted that hypertension in patients with renal insufficiency of any origin is a major risk factor. Strict control of hypertension can delay or prevent the progression of renal insufficiency to endstage renal failure. The role of dietary protein restriction in preventing the progression of renal failure has not yet been established. Although the results of many investigations support a beneficial effect of protein restriction, its wide-scale application should await definite documentation. The National Institute of Diabetes and Digestive and Kidney Diseases is currently sponsoring a multicenter controlled study of the effects of several dietary protein regimens on the progression of renal failure in patients with varying degrees of renal insufficiency. The study will be completed in 2 years, and the
Phase III trial of low-level laser therapy to prevent induced oral mucositis in head and neck cancer patients submitted to concurrent chemoradiation.
Authors: H. S. Antunes, D. Herchenhorn, C. M. Araujo, E. Cabral, E. M. d. S. Ferreira, I. A. Small, M. P. Rampini, N. Teich, P. C. Rodrigues, T. G. P. d. Silva, L. F. Dias, C. G. M. Ferreira
Journal: Journal of Clinical Oncology (2011)

LBA5524 The full, final text of this abstract will be available in Part II of the 2011 Annual Meeting Proceedings, distributed onsite at the Meeting on June 4, 2011, and as a supplement to the June 20, 2011, issue of Journal of Clinical Oncology.
Manuali Hoepli: Spiritismo.
Journal: JAMA (1898)

<b>Magnetismo e Ipnotisma.</b>Per ilDott. G. Belfiore. Milano: Ulrico Hoepli. 1898. These are two of the more recent of the little pocket manuals issued by the Italian house of Ulrico Hoepli. The first of these discusses the phenomena of spiritualism in rather a more respectful manner than an American medical author would; the second is a discussion of the phenomena of hypnotism according to the latest European literature of the subject. Both are compilations, but such have a very useful function and will probably be serviceable to those who can read them. While spiritualism has interest only as a psychic aberration, and some of the literature of hypnotism also has in it a larger element of human credulity than is consistent with genuine science, such manuals as these are not without interest, and that on hypnotism appears to be on the whole a fair statement of verified facts.
EARLY MEDICINE IN MARYLAND.
Journal: JAMA (1902)

Among the interesting historical papers on the early history of medicine in this country, published in the Bulletin of the Johns Hopkins Hospital, not the least interesting is that by Dr. Eugene Cordell on the Transactions of the Harford Medical Society in the August and September issue. It gives in its extracts and comments on the same, with its historical data attached, what must be in many respects a good idea of the medical practice in Maryland at the close of the eighteenth century. In some respect it is a closer picture of the average of practice at that date than can be gained from the periodical publications of the same period—which are practically limited to one—the Medical Repository— since in the latter a stricter editorial scrutiny has probably given only a selected or blue-penciled and revised version of the medical contributions of the time. The treatment of those days
The impact of a physician as part of the aeromedical prehospital team in patients with blunt trauma
Authors: W. G. Baxt
Journal: JAMA (1987)

To determine whether the presence of a physician in the prehospital setting influences patient outcome, the predicted mortality of 258 patients with blunt trauma treated and transported by a medical helicopter staffed by a flight nurse and flight paramedic was compared with that of 316 similar patients with blunt trauma treated and transported by a medical helicopter staffed by a flight nurse and flight physician. All patients were randomized between the two treatment teams. The mortality of the patients treated by the flight nurse/flight paramedic team was that predicted by the methodology. The mortality of the patients treated by the flight nurse/flight physician team was 35% lower than that predicted, and significantly lower than that of the flight nurse/flight paramedic—staffed helicopter. (<i>JAMA</i>1987;257:3246-3250)
Egr2 targets identify a population of dysfunctional T cells in the tumor microenvironment with immune modulatory properties
Authors: Jason Williams, Yan Zheng, Thomas Gajewski
Journal: Journal for ImmunoTherapy of Cancer (2013)

Meeting abstracts The immune recognition of cancer provides potential for robust host control of tumors. Although the presence of tumor-infiltrating lymphocytes (TILs) indicates an endogenous anti-tumor response, immune regulatory pathways can subvert the effector phase and enable tumor escape.
Evaluation of urine-based screening strategies to detect Chlamydia trachomatis among sexually active asymptomatic young males
Authors: M. A. Shafer
Journal: JAMA (1993)

<h3>Objective.</h3> —To evaluate the performances of diagnostic screening tests alone or in combination to detect asymptomatic chlamydial urethral infection in young males. <h3>Design.</h3> —Comparisons of the performance profiles of the following chlamydia screening strategies were done: urethral culture; identification of polymorphonucleocytes (PMNs) on spun first-void urine (FVU); urinary leukocyte esterase test (LET) on unspun FVU; chlamydial enzyme immunoassay (EIA) applied to FVU sediment; combining LET on unspun FVU followed by EIA with or without direct fluorescent antibody (DFA) confirmation on FVU sediment; and combining PMNs on spun FVU followed by EIA with or without DFA confirmation. <h3>Setting.</h3> —General clinics at a youth detention center, university-based teen clinic, college health service, and a military screening clinic. <h3>Patients.</h3> —A total of 618 males aged 12 to 35 years (mean, 17 years) were recruited as a convenience sample; site participation rates ranged from 50% to 80%. Eligible subjects were sexually active, denied symptoms of urethritis, and had taken no antibiotics in the prior 2 weeks. <h3>Main Outcome Measures.</h3> —Sensitivity, specificity, and positive and negative predictive values of each test strategy's ability to detect<i>Chlamydia trachomatis</i>infection, and cost to confirm each positive case. <h3>Results.</h3> —With a 7% prevalence of chlamydial infection, tissue culture had a sensitivity of only 61%. However, two strategies yielded significantly better performance profiles compared with the others: EIA confirmed by DFA test with a sensitivity of 84%, a specificity of 100%, and a cost to identify each positive case of $434; and PMNs followed by EIA confirmed by DFA test with a sensitivity of 78%, a specificity of 100%, and a cost to identify each positive case of $199. The LET followed by EIA-DFA had a similar performance profile to the PMN test strategies. <h3>Conclusions.</h3> —A combination of a nonspecific screening of FVU for PMNs or LET followed by specific testing with EIA with DFA confirmation has superior clinical and cost-effective performance for detecting asymptomatic<i>C trachomatis</i>urethritis in young males compared with other strategies. However, an evaluation of the medical, fiscal, and psychological benefits and risks associated with a specific screening strategy for sexually transmitted diseases must be made before adopting a specific strategy for a particular population. (<i>JAMA</i>. 1993;270:2065-2070)