tbuckley/cabot-search huggingface dataset:
The Cover
Authors: M. Therese Southgate
Journal: JAMA (1987)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Erratum: Alterations of the Arginine Metabolome in Asthma
Authors: Gwenael Lorillon, Anne Bergeron, Laurence Detourmignies, Stéphane Jouneau, Benoit Wallaert, Jacques Frija, Abdellatif Tazi
Journal: American Journal of Respiratory and Critical Care Medicine (2012)

he complained of stage III WHO functional class dyspnea.Of note, he had begun smoking 5 years earlier.A lung HRCT scan demonstrated extensive bullocystic lesions predominantly in the lower regions of the lung (9).Despite treatment with vinblastine and corticosteroids, his lung function deteriorated (total lung capacity [TLC]: 77%; FVC: 47%; FEV 1 : 37%; residual volume [RV]: 163%; DL CO : 37% of predicted; FEV 1 /FVC: 68%).After treatment with cladribine, his dyspnea improved to stage II.Strikingly, on serial lung HRCT scan, the confluent bullocystic lesions had almost completely resolved, whereas the lung volume had decreased (Figures 1C-1F).In parallel, his RV and TLC values decreased (respectively to 100 and 67% of predicted).In contrast, his FEV 1 and FVC levels had, respectively, increased by 71 and 40% compared with the pretreatment values.These results clearly demonstrate that an isolated cystic pattern observed on lung HRCT in patients with PLCH does not necessarily represent end-stage disease (10,11).A randomized controlled trial is strongly needed to assess the effectiveness and tolerance of cladribine in a larger population of patients with progressive PLCH.
Economic evaluation of bivalirudin with provisional glycoprotein IIB/IIIA inhibition versus heparin with routine glycoprotein IIB/IIIA inhibition for percutaneous coronary interventionResults from the REPLACE-2 trial
Authors: D COHEN, A LINCOFF, T LAVELLE, H CHEN, A BAKHAI, R BEREZIN, D JACKMAN, I SAREMBOCK, E TOPOL
Journal: Journal of the American College of Cardiology (2004)
Publisher Correction: A community-based transcriptomics classification and nomenclature of neocortical cell types
Authors: Rafael Yuste, Michael Hawrylycz, Nadia Aalling, Argel Aguilar-Valles, Detlev Arendt, Ruben Armananzas Arnedillo, Giorgio A. Ascoli, Concha Bielza, Vahid Bokharaie, Tobias Borgtoft Bergmann, Irina Bystron, Marco Capogna, Yoonjeung Chang, Ann Clemens, Christiaan P. J. de Kock, Javier DeFelipe, Sandra Esmeralda Dos Santos, Keagan Dunville, Dirk Feldmeyer, Richárd Fiáth, Gordon James Fishell, Angelica Foggetti, Xuefan Gao, Parviz Ghaderi, Natalia A. Goriounova, Onur Güntürkün, Kenta Hagihara, Vanessa Jane Hall, Moritz Helmstaedter, Suzana Herculano, Markus M. Hilscher, Hajime Hirase, Jens Hjerling-Leffler, Rebecca Hodge, Josh Huang, Rafiq Huda, Konstantin Khodosevich, Ole Kiehn, Henner Koch, Eric S. Kuebler, Malte Kühnemund, Pedro Larrañaga, Boudewijn Lelieveldt, Emma Louise Louth, Jan H. Lui, Huibert D. Mansvelder, Oscar Marin, Julio Martinez-Trujillo, Homeira Moradi Chameh, Alok Nath, Maiken Nedergaard, Pavel Němec, Netanel Ofer, Ulrich Gottfried Pfisterer, Samuel Pontes, William Redmond, Jean Rossier, Joshua R. Sanes, Richard Scheuermann, Esther Serrano-Saiz, Jochen F. Steiger, Peter Somogyi, Gábor Tamás, Andreas Savas Tolias, Maria Antonietta Tosches, Miguel Turrero García, Hermany Munguba Vieira, Christian Wozny, Thomas V. Wuttke, Liu Yong, Juan Yuan, Hongkui Zeng, Ed Lein
Journal: Nature Neuroscience (2020)
Novel therapies to prevent diabetic retinopathy
Authors: A. A. Skolnick
Journal: JAMA (1997)

Normal retina (left); retina of a patient with diabetes and proliferative retinopathy (right). "The eye with diabetic retinopathy provides a unique 'window' for noninvasively studying the vascular damage diabetes causes in the kidney and other organs," said Robert Goldstein, MD, PhD, vice president for research, Juvenile Diabetes Foundation International. THANKS TO recent advances in understanding how hyperglycemia may damage blood vessels in the eyes of patients with diabetes, several novel therapies for preventing diabetic retinopathy are now under study. The latest research on potential therapies was discussed at the Juvenile Diabetes Foundation International (JDFI) Oxford Conference on Diabetic Retinopathy, at St John's College, Oxford University, Oxford, England, in September. The conference, which was sponsored by the JDFI (headquartered in New York, NY) and the European Association for the Study of Diabetes, brought together many of the world's leading investigators of the pathogenic mechanisms behind diabetic retinopathy and other complications of
Exercise therapy versus arthroscopic partial meniscectomy for degenerative meniscal tear in middle aged patients: randomised controlled trial with two year follow-up
Authors: Nina Jullum Kise, May Arna Risberg, Silje Stensrud, Jonas Ranstam, Lars Engebretsen, Ewa M Roos
Journal: British Journal of Sports Medicine (2016)

To determine if exercise therapy is superior to arthroscopic partial meniscectomy for knee function in middle aged patients with degenerative meniscal tears.Randomised controlled superiority trial.Orthopaedic departments at two public hospitals and two physiotherapy clinics in Norway.140 adults, mean age 49.5 years (range 35.7-59.9), with degenerative medial meniscal tear verified by magnetic resonance imaging. 96% had no definitive radiographic evidence of osteoarthritis.12 week supervised exercise therapy alone or arthroscopic partial meniscectomy alone.Intention to treat analysis of between group difference in change in knee injury and osteoarthritis outcome score (KOOS4), defined a priori as the mean score for four of five KOOS subscale scores (pain, other symptoms, function in sport and recreation, and knee related quality of life) from baseline to two year follow-up and change in thigh muscle strength from baseline to three months.No clinically relevant difference was found between the two groups in change in KOOS4 at two years (0.9 points, 95% confidence interval -4.3 to 6.1; P=0.72). At three months, muscle strength had improved in the exercise group (P≤0.004). No serious adverse events occurred in either group during the two year follow-up. 19% of the participants allocated to exercise therapy crossed over to surgery during the two year follow-up, with no additional benefit.The observed difference in treatment effect was minute after two years of follow-up, and the trial's inferential uncertainty was sufficiently small to exclude clinically relevant differences. Exercise therapy showed positive effects over surgery in improving thigh muscle strength, at least in the short term. Our results should encourage clinicians and middle aged patients with degenerative meniscal tear and no definitive radiographic evidence of osteoarthritis to consider supervised exercise therapy as a treatment option.www.clinicaltrials.gov (NCT01002794).
THE NEW ROYAL VICTORIA HOSPITAL, BELFAST
Journal: BMJ (1903)

IN the planning, construction, and furnishing of a large hospital associated with a medical school in a city like Belfast, the main considerations to be kept in view are as follows 1.The institution should be sufficiently large to be self- contained, it should be accessible, and it should occupy a position in which it cannot be deprived of light and air by contiguous buildings, or be fouled by the smoke from adjacent manufactories.which the principal considerations are perfection of work and its accomplishment with care and despatch, while at the same time this maximum of efficiency should be secured at the minimum of cost.How far has the new Royal Victoria Hospital, erected as the outcome of a movement which began in December, 1896, during the mayoralty of the Right Hon.
This week in the BMJ: Three days of amoxicillin are enough for non-severe pneumonia
Journal: BMJ (2004)

procedure, entailing the implantation of a temporary device with a neuromodulation unit only slightly larger than a pager attached to the patient's regular pant belt.This stage 1 procedure is performed under local anaesthesia and takes less than 45 minutes.If the patient's symptoms improve by more than 50%, a permanent device is implanted in either buttock with a 6 cm incision.The device can be programmed via an extracorporeal handheld device for increases or decreases in power magnitude.The effects on nocturia have been remarkable, with a reduction of more than 60% in episodes of nocturia, even in patients taking diuretic medication.Adverse events such as pain at the implant site, lead migration, infection or skin irritation, or technical or device related problems are possible in up to one third of patients, and contraindications such as benign prostatic hypertrophy, cancer, or urethral stricture may exclude some patients from candidacy for the procedure 24 ; in general, however, sacral neuromodulation is an effective, safe, and reversible treatment and offers an important new option 22 for patients with symptoms of urgency, urge incontinence, and nocturia.
The Radiology of Cardiac Pacemakers
Authors: Robert M. Steiner
Journal: JAMA (1978)

THE USE of permanent cardiac pacemakers is now a well-established procedure. It is estimated that more than 150,000 units have been employed since Chardack et al<sup>1</sup>introduced the first self-contained, fixedrate implantable pacemaker in 1960. Since that time, remarkable progress has been made in developing longerlived power resources, durable electrode and generator components, and more versatile pacing modes. The role of the radiologist is important in aiding the surgeon and the cardiologist during the initial examination of the patient and during the immediate and late postimplantation follow-up period. <h3>Pacemaker Implantation</h3> Following insertion of the pacemaker, films in the posteroanterior and lateral projections should be exposed as soon as possible. This may be done in the operating room, where an overhead tube assembly or a portable roentgenographic machine should be available. Lateral films of the chest are exposed using the horizontal beam with the patient in the supine position. If
Masthead: (Adv. Healthcare Mater. 22/2016)
Journal: Advanced Healthcare Materials (2016)

Citizenship: Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have focused on sharing our content with those in need, enhancing community philanthropy, reducing our carbon impact, creating global guidelines and best practices for paper use, establishing a vendor code of ethics, and engaging our colleagues and other stakeholders in our efforts.
Pretraining for International Medical Graduates
Authors: Padmaja Polavarapu
Journal: Annals of Internal Medicine (1993)

Letters1 March 1993Pretraining for International Medical GraduatesPadmaja Polavarapu, MDPadmaja Polavarapu, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-118-5-199303010-00026 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:“International medical graduate” is used by Dr. Levey [1] as an attempt to decrease the negative stigmata associated with the term “foreign medical graduate.” However, Dr. Levey's recommendation of evaluation and training solely for international medical graduates suggests a negative attitude.Program directors must maintain the highest standards for internal medicine residents, and it would be more appropriate to re-evaluate the internal medicine postgraduate entrance process for all prospective residents. My experience as a foreign medical graduate in an internal medicine residency program, together with other studies [2], leads me to conclude that Dr. Levey's “pre”-postgraduate training ...References1. Levey GS. Internal medicine and the training of international medical graduates: a time for open discussion and new approaches. Ann Intern Med. 1992; 117:403-7. Google Scholar2. Norcini JJ. Changes in the medical knowledge of candidates for certification. Ann Intern Med. 1991; 114:33-5. Google Scholar3. Potts JT Jr. Recruitment of minority physicians into careers in internal medicine. Ann Intern Med. 1992; 116(12 pt 2):1099-102. Google Scholar Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byImmigrant Health Care Providers in the United States 1 March 1993Volume 118, Issue 5Page: 396-398KeywordsContinuing medical educationGraduate medical educationResidency ePublished: 15 August 2000 Issue Published: 1 March 1993 Copyright & PermissionsCopyright © 1993 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Generalized pustular psoriasis induced by potassium iodide. A postulated role for dihydrofolic reductase
Authors: W. B. Shelley
Journal: JAMA (1967)

Two patients with recurrent generalized pustular psoriasis of von Zumbusch were studied. Systemic manifestations of this disease included hepatitis, fever, leukocytosis, hypoproteinemia, hypocalcemia, and elevations of serum transaminase and alkaline phosphatase levels. Typical attacks were induced by challenge with 500 mg of orally administered potassium iodide. Salicylates also appeared to have an adverse effect. By strict avoidance of iodides and salicylates prolonged complete remissions were achieved in both patients. However, in one patient premenstrual flares occurred and a single oral challenge with 5 mg of progesterone was followed by a minor clinical attack of pustular psoriasis. It is postulated that iodides trigger attacks by stimulating the activity of cellular dihydrofolic reductase, essential in the metabolic pathways involved in the cell division necessary for the clinical expression of the disease. Inhibition of this enzyme by folic acid antagonists is known to produce remissions in the disease. Further study of the folic acid pathway in psoriasis is needed.
Psychiatry
Authors: H. Stewart, M. L. Hare, J. F. Shaw, J. C. Mougne
Journal: BMJ (1966)

<h3>Abstract</h3> A wide range of neurological manifestations have been associated with the development of COVID-19 following SARS-CoV-2 infection. However, the etiology of the neurological symptomatology is still largely unexplored. Here, we used state-of-the-art multiplexed immunostaining of human brains (<i>n</i> = 6 COVID-19, median age = 69,5 years; and <i>n</i> = 7 control, median age = 68 years), and demonstrated that expression of the SARS-CoV-2 receptor ACE2 is restricted to a subset of neurovascular pericytes. Strikingly, neurological symptoms were exclusive to, and ubiquitous in, patients that exhibited moderate to high ACE2 expression in peri-vascular cells. Viral particles were identified in the vascular wall and paralleled by peri-vascular inflammation, as signified by T cell and macrophage infiltration. Furthermore, fibrinogen leakage indicated compromised integrity of the blood-brain barrier. Notably, cerebrospinal fluid from an additional 16 individuals (<i>n</i> = 8 COVID-19, median age = 67 years; and <i>n</i> = 8 control, median age = 69,5 years) exhibited significantly lower levels of the pericyte marker PDGFRβ in SARS-CoV-2-infected cases, indicative of disrupted pericyte homeostasis. We conclude that pericyte infection by SARS-CoV-2 underlies virus entry into the privileged central nervous system space, as well as neurological symptomatology due to peri-vascular inflammation and a locally compromised blood-brain barrier.
The Addis Count
Journal: JAMA (1942)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Risk factors for acute non-A, non-B hepatitis in the United States and association with hepatitis C virus infection
Authors: M. J. Alter
Journal: JAMA (1990)

The Centers for Disease Control conducted intensive surveillance for acute non-A, non-B hepatitis in four sentinel counties over a 7-year period. Testing for antibody to hepatitis C virus was performed with the newly developed enzyme immunoassay. The incidence of non-A, non-B hepatitis remained relatively stable (average, 7.1 cases per 100 000), but there were significant changes in disease transmission patterns. The proportion of patients with a history of blood transfusion declined from 17% to 6%, but the proportion with a history of parenteral drug use increased from 21% to 42%. The proportion of patients with histories of sexual exposure (6%), household exposure (3%), occupational exposure to blood (2%), or hemodialysis (0.6%) did not change over time. Antibody to hepatitis C virus was found in 45% of patients within 6 weeks of onset of illness and in 68% of patients followed up for at least 6 months. Patients with no history of transfusions were just as likely to be positive for antibody to hepatitis C virus as patients with transfusion-associated hepatitis, indicating that hepatitis C virus is the major causative agent of all non-A, non-B hepatitis in the United States. (<i>JAMA</i>. 1990;264:2231-2235)
Evaluation of the Sanborn-Frommer Particle Counter for Counting Leukocytes
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Prevalence of antibody to hepatitis C virus among Saudi Arabian children: A community-based study
Authors: F Al-Faleh
Journal: Hepatology (1991)

In a population-based survey, 39 (0.90%) of 4,496 Saudi Arabian children (ages 1 to 10) were positive for antibody to hepatitis C virus. No significant difference was seen between the prevalence rate in males (0.9%) and females (0.8%) or between urban (0.7%) and rural dwellers (1.0%). A significant variation of rates (0% to 5.7%) was seen from one region to another. The Gizan population, noted for hyperendemic hepatitis B virus infection, had the highest prevalence of antibody to hepatitis C virus despite its cultural and socioeconomic similarities to other regions. In some regions of Saudi Arabia the prevalence of antibody to hepatitis C virus among children was 0% despite endemic rates for both hepatitis B virus and hepatitis A virus infections. An inverse relationship between age and antibody to hepatitis C virus positivity was noted, suggesting an early acquisition of infection in the population studied. Although the overall prevalence of antibody to hepatitis C virus in Saudi children appears low, endemic foci exist where transmission of infection appears to occur early in childhood. The significance of this characteristic for the incidence of chronic sequelae of hepatitis C virus infection needs further evaluation. (HEPATOLOGY 1991;14:215–218.)
Another Explanation.
Authors: Jerome Cochran
Journal: JAMA (1896)

Montgomery, Ala., July6, 1896. <h3>To the Editor:</h3> —I am sorry to have to trouble you with another explanation. But please allow me to say that I did not advocate before the Conference of State Boards of Health any such scheme of organization as that which you ascribe to me, nor anything in any way resembling it.<sup>1</sup>You are certainly writing under the influence of information that is entirely incorrect. This will be plain when the official Report of the Proceedings of the Conference of State Boards are published. The proposed bill has not taken definite shape. Only its larger provisions have been decided upon. It is some little time yet before Congress meets; and ever since the session of theAssociationin Atlanta I have been in a most miserable condition of health; during the last two weeks I have been in bed. Under these circumstances I have