tbuckley/cabot-search huggingface dataset:
RESTRICTION OF VICE AMONG SOLDIERS.
Journal: JAMA (1900)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Journal of Clinical Pathology, London
Journal: JAMA (1964)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Syphilis and Its Management
Authors: Nicholas J. Fiumara, Bernard Appel, William Hill, Herbert Mescon
Journal: New England Journal of Medicine (1956)

THE venereal diseases are on the rise again. During the last six months of 1954, forty-three states reported an increase in early syphilis or gonorrhea or both.1 That syphilis is still a nation-wide problem is evident from the United States Public Health Service estimate that as of December 31, 1955, there were approximately 2,000,000 people in the United States with syphilis requiring treatment. During 1955 approximately 86,800 new cases of syphilis occurred among the civilian population.2 The foregoing means that a reservoir of infectious syphilis exists in most communities. Because of the limitations of present control methods, this reservoir cannot . . .
Studies on Digitalis VI: Reduction of Oxygen Debt After Exercise with Digoxin in Cardiac Patients Without Heart Failure
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
How the AMA develops policy
Authors: J. Stacey
Journal: JAMA (1983)

FEW ORGANIZATIONS are as rigorously democratic as the American Medical Association. Twice each year, its policymaking House of Delegates convenes to debate and act on a wide range of issues affecting medicine. Everything from attitudes toward arctic research to approaches to competition in the provision of medical services is given thorough scrutiny. And a representative voice from virtually every branch of medicine is offered an opportunity to be heard. It is a somewhat Herculean task, involving mastery of hundreds of closely written pages of information supporting 220 or more resolutions and reports to be acted on at every meeting. Most of the information is mailed to delegates before the meeting begins. Additional resolutions typically await delegates when they reach the meeting site. The 351 delegates, and like number of alternate delegates, are expected to assimilate the material and act on it in a judicious fashion, taking into account the action's
CONTINUING MEDICAL EDUCATION— DOES IT MATTER?
Journal: JAMA (1966)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Leukaemia and L.S.D.
Journal: BMJ (1969)

PointersMalaria in Britain: Investigation into over 2,000 cases of imported malaria indicates that had prophylactic drugs been continued for one month after leaving endemic area probably none of these cases would have occurred (p. 781).Leader, p. 776.Two cases in Glasgow (p.831).Myometrial Activity: Both oestriol sulphate and placebo when administered intra-amniotically over a six-hour period to post-mature young primiparae increased uterine contractions at four and six hours (p.786). Hyperparathyroidism:Radioimmunoassay showed hypersecretion by adenoma, and serial estimations following its removal showed a rapid fall in concentration (p.789).Carbenoxolone Effects: Metabolic studies suggest that mineralocorticoid effects are due to intrinsic aldosterone-like action (p.793).Platelets and Surgery: Studies in patients having open cardiac surgery suggest that prevalence of thromboembolism after valve replacement may be due partly to changes in platelet behaviour (p.795).Cortisol Levels: Levels in 13 women on oral contraceptives were increased threefold over normal subjects (p.798).Leukaemia after L.S.D.: Report of second case.Unusual bone-marrow chromosome pattern suggests 'this association may be causal (p.800).Leader this page.Deep-vein Thrombosis: Diagnostic ultrasonic technique found to be quick, simple, and results compared favourably with phlebography (p.802).Case Reports: Muscle cramp due to acute hypo-
Birth Mark?
Authors: J. M. G. Carter
Journal: JAMA (1898)

Waukegan, Ill., Jan. 6, 1898. <h3>To the Editor:</h3> —J. F. M. is 13 years old, and is usually in good health. He is myopic and his eyes are elongated antero-posteriorly. The pupils are exactly alike, ellipto-oval in shape, the pointed portion of the pupil being downward like a snake's eye. The mother thinks the boy is "marked." While she was pregnant, a few months before his birth, she was frightened by a snake and for weeks afterward she fancied she could see that snake's eyes. Is the boy "marked"? Respectfully,
Modified Ayre's T-Tube Technique-Anesthesia for Cleft Lip and Palate Surgery
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Cyclobenzaprine in intractable pain syndromes with muscle spasm
Authors: B. R. Brown
Journal: JAMA (1978)

The effectiveness of cyclobenzaprine hydrochloride, a new tricyclic skeletal muscle relaxant, was shown in patients with long-term intractable pain of cervical and lumbar origin aggravated by skeletal muscle spasm and tenderness. The investigation was double-blind and randomized, comparing cyclobenzaprine hydrochloride (10 mg three times a day) with diazepam (5 mg three times a day) and with placebo. After two weeks of treatment, the 16 patients in the cyclobenzaprine group showed an overall improvement in pain variables as did the 16 patients in the diazepam group. No serious adverse reactions to cyclobenzaprine were observed in the study. However, dry mouth due to cyclobenzaprine's anticholinergic action and mild degrees of drowsiness were encountered more often than with diazepam or placebo. (<i>JAMA</i>240:1151-1152, 1978)
Bile leakage following Menghini needle liver biopsy
Authors: M. L. Kelley
Journal: JAMA (1971)

<h3>To the Editor.—</h3> This report documents an unusual complication of needle biopsy of the liver by the Menghini technique, namely, bile leakage in a patient with low-grade obstructive jaundice. <h3>Report of a Case.—</h3> A 74-year-old white housewife was admitted to the Mary Hitchcock Memorial Hospital on May 15, 1969, for the evaluation of jaundice. The patient had felt well until February of 1969. at which time she became depressed and complained of nondescript "throat discomfort." On May 9, she noted dark urine and light stools and on May 10, was observed to be icteric. There was no pruritus. In 1959, a radical mastectomy on the right side had been performed for adenocarcinoma of the breast with axillary metastases. The patient's only medication had been phenobarbital, 0.016 gm, three times a day. The results of blood chemical analyses reflecting liver function are summarized in the Table. On May 20, 1969, needle
Hemolytic anemia due to antibodies to penicillin
Authors: M. Lai
Journal: JAMA (1966)

ANTIBODIES to penicillin in the sera of patients receiving this drug therapeutically were first described and characterized by Ley et al in 1958.<sup>1</sup>Such antibodies have been reported to occur with an incidence of 29%<sup>2</sup>and 30.5%<sup>3</sup>in the sera of patients with penicillin hypersensitivity and from 1% to 4%<sup>1,2,4</sup>in random sera. Penicillin antibodies are detected by their affinity for red blood cells.<sup>1</sup> Despite the relatively high incidence of untoward reactions to penicillin, and the even more frequent occurrence of penicillin antibody development,<sup>2,3</sup>very few cases have been reported<sup>5-9</sup>in which acquired hemolytic anemia was associated with penicillin antibodies. The case reported here demonstrates hemolytic anemia in a patient receiving massive doses of intravenously administered penicillin. <h3>Report of a Case</h3> A 42-year-old woman was admitted to the hospital because of fever, sore throat, cough, and malaise that developed nine days earlier and
Benzene Adducts with Rat Nucleic Acids and Proteins: Dose-Response Relationship after Treatment In Vivo
Authors: Mario Mazzullo, Silvana Bartoli, Bruna Bonora, Annamaria Colacci, Sandro Grilli, Giovanna Lattanzi, Alessandra Niero, Maria Paola Turina, Silvio Parodi
Journal: Environmental Health Perspectives (1989)

The dose-response relationship of the benzene covalent interaction with biological macromolecules from rat organs was studied. The administered dose range was 3.6 x 10(7) starting from the highest dosage employed, 486 mg/kg, which is oncogenic for rodents, and included low and very low dosages. The present study was initially performed with tritium-labeled benzene, administered by IP injection. In order to exclude the possibility that part of the detected radioactivity was due to tritium incorporated into DNA from metabolic processes, 14C-benzene was then also used following a similar experimental design. By HPLC analysis, a single adduct from benzene-treated DNA was detected; adduct identification will be attempted in the near future. Linear dose-response relationship was observed within most of the range of explored doses. Linearity was particularly evident within low and very low dosages. Saturation of benzene metabolism did occur at the highest dosages for most of the assayed macromolecules and organs, especially in rat liver. This finding could be considered as indicative of the dose-response relationship of tumor induction and could be used in risk assessment.
Burr-Hole Buttons for Fixation of Craniotomy Bone
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Of mind and morbidity: can stress and grief depress immunity?
Authors: C. Macek
Journal: JAMA (1982)

"Do you remember—in one of Woody Allen's movies—when he says, 'I don't get depressed. I grow a tumor instead.'? "This shows that the studies on personality, stress, and cancer, although still definitely not conclusive, have already made their way into the common consciousness," says Joan Borysenko, PhD, instructor of medicine, Division of Behavioral Medicine, Beth Israel Hospital and Harvard Medical School, Boston. Once relegated mainly to faith healers and practitioners of folk medicine, the idea that the conscious mind can influence the onset and outcome of a variety of diseases now is accepted by many medical and lay persons. In fact, the quest to discern the physiological mechanisms behind this poorly understood relationship has given birth to a hybrid discipline—psychoneuroimmunology—that was the topic of a recent meeting in New York City on mind and immunity as well as of several presentations at the American Psychosomatic Society meeting in Denver. "I
Screening with prostate-specific antigen: should we or shouldn't we?
Authors: J. E. Herbers
Journal: JAMA (1993)

<h3>To the Editor.</h3> —In a recent Editorial<sup>1</sup>Lange reviewed the current evidence for prostate cancer screening. He described the key unresolved issue: whether screening should be done at all in asymptomatic men, given that there is no proof that early diagnosis leads to better health outcomes. I therefore did not understand the basis for his concluding recommendation that "for now the periodic prostate examination should be encouraged" pending the results of ongoing clinical trials. The opposite conclusion seems more appropriate. Sackett and colleagues<sup>2</sup>have described screening for symptom-free individuals in terms of an implicit contract. By this view, we imply a promise to asymptomatic people "not that their subsequent treatment may work but that it does work; not that we will simply do our best, but that they will be better off as a result of the screening program. When we impose ourselves on the public in this
Hazards From Thermodecomposition of Epoxy Resins
Journal: JAMA (1963)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Leads from the MMWR. Mumps--United States, 1980-1983
Journal: JAMA (1983)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
FDA Approves Kadcyla for Breast Cancer
Journal: Cancer Discovery (2013)

Abstract The U.S. Food and Drug Administration approved the antibody–drug conjugate (ADC) ado-trastuzumab emtansine (Kadcyla; Genentech) for the treatment of HER2-positive metastatic breast cancer. Also known as T-DM1, the therapy is intended for patients who have previously been treated with trastuzumab and a taxane.
Resource document for curriculum development in cancer genetics education. American Society of Clinical Oncology.
Journal: Journal of Clinical Oncology (1997)

PURPOSE The rapid growth in the use of genetic testing for heritable cancers and other diseases has led to the establishment of many committees to assess the status and future implications of such testing. The American Society of Clinical Oncology (ASCO) published a statement on genetic testing for cancer susceptibility in May 1996. In that statement, ASCO recognized the need for a major initiative to develop courses and other educational materials for ASCO members and other health care professionals that were pertinent to cancer genetics and the role of cancer predisposition testing in clinical oncology. These curriculum guidelines represent an effort to promote formal instruction on the assessment and management of familial cancer risks in training programs and continuing education courses. DESIGN AND RESULTS An Ad hoc Task Force was created from the ASCO membership and other professional organizations. Goals of ASCO's cancer genetics education initiative, curriculum guidelines, and plans for implementation of the curriculum have been developed. To gain understanding and competency in cancer genetics and cancer predisposition testing, the curriculum emphasizes formal instruction in: (1) basic concepts and principles of genetics; (2) an understanding of the role of genetics in the etiology, diagnosis, and management of different malignancies; (3) an understanding of the ethical, legal, and social issues that surround predisposition testing; and (4) long-term management plans for individuals at high risk for cancer. This document is broad in scope and applicable to all types of malignancies. It should be considered as the framework around which cancer genetics education is developed. It is expected that implementation of training activities over the next few years will allow ASCO to fulfill its obligations to the membership. CONCLUSION This curriculum should prove a valuable guide to those who wish further education on cancer genetics and the appropriate use of cancer predisposition testing.