ENCEPHALITIS FOLLOWING VACCINATION AGAINST PERTUSSIS
Authors: P. W. C.
Journal: Annals of Internal Medicine (1950)

Editorial1 February 1950ENCEPHALITIS FOLLOWING VACCINATION AGAINST PERTUSSISP. W. C.P. W. C.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-32-2-343 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSevere injury of the brain ("encephalitis") and spinal cord has been observed as an immediate or early sequel of many immunization procedures, including the inoculation of living vaccines, killed bacterial suspensions or other culture materials, and prophylactic antisera. The incidence of such reactions is, in general, extremely low, so low that any one individual even if actively engaged in this type of work is likely to see only a few such cases in a life time. The results of such injuries, however, are often so devastating that the possibility of their occurrence should be generally realized.The earliest recognized and...1 TurnbullMcIntosh HMJ: Encephalomyelitis following vaccination, Brit. J. Exper. Path. 7: 181-222, 1926. Google Scholar2 Madsen T: Vaccination against whooping cough, J. A. M. A. 101: 187-188, 1933. CrossrefGoogle Scholar3 Doul JA: Active immunization against whooping cough, Am. J. Pub. Health 26: 1097-1105, 1936. CrossrefGoogle Scholar4 Taylor HW: Reaction following injection of pertussis vaccine-Sauer, Arch. Pediat. 55: 572, 1938. Google Scholar5 KendrickEldring PG: A study in active immunization against pertussis, Am. J. Hyg. 29: 133-153, 1939. Google Scholar6 Sako W: Early immunization against pertussis with alum precipitated vaccine, J. A. M. A. 127: 379-384, 1945. CrossrefGoogle Scholar7 WerneGarrow JI: Fatal anaphylactic shock. Occurrence in identical twins following second injection of diphtheria toxoid and pertussis antigen, J. A M. A. 131: 730-733, 1946. CrossrefMedlineGoogle Scholar8 Brody M: Neurological complications following administration of pertussis vaccine, J. A. M. A. 140: 555-556, 1949. CrossrefGoogle Scholar9 ByersMoll RKFC: Encephalopathies following prophylactic pertussis vaccine, Pediatrics, 1: 407-457, 1948. Google Scholar10 Toomey JA: Reactions to pertussis vaccine, J. A. M. A. 139: 448-449, 1949. CrossrefMedlineGoogle Scholar11 GlobusKohn JHJL: Encephalopathy following pertussis prophylaxis, J. A. M. A. 141: 507-509, 1949. CrossrefMedlineGoogle Scholar12 Ferraro A: Pathology of demyelinating diseases as an allergic reaction of the brain, Arch. Neurol. and Psychiat. 52: 443-483, 1944. CrossrefGoogle Scholar13 Finley KH: Pathogenesis of encephalitis occurring with vaccination, variola and measles, Arch. Neurol. and Psychiat. 39: 1047-1054, 1939. CrossrefGoogle Scholar14 RiversSchwentker TMFF: Encephalomyelitis accompanied by myelin destruction experimentally produced in monkeys, J. Exper. Med. 61: 689-702, 1935. CrossrefMedlineGoogle Scholar15 Morgan IM: Allergic encephalomyelitis in monkeys in response to injection of normal monkey nervous tissue, J. Exper. Med. 85: 131-140, 1947. CrossrefMedlineGoogle Scholar16 Kabat EA: Rapid production of acute disseminated encephalomyelitis in rhesus monkeys by injection of heterologous and homologous brain tissue with adjuvants, J. Exper. Med. 85: 117-130, 1947. CrossrefMedlineGoogle Scholar17 Kennedy F: Certain nervous complications following use of therapeutic and prophylactic sera, Am. J. M. Sc. 177: 555, 1929. CrossrefGoogle Scholar18 WinklemanGotten NWN: Encephalomyelitis following the use of serums and vaccines, Am. J. Syph. and Neurol. 19: 414-424, 1935. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 February 1950Volume 32, Issue 2Page: 343-348KeywordsBacterial culturesBrainEncephalitisInoculationPertussisSpinal cordVaccines ePublished: 1 December 2008 Issue Published: 1 February 1950 PDF downloadLoading ...