tbuckley/cabot-search huggingface dataset:
Paracardiac cyst: diagnosis by ultrasound and puncture
Authors: R. O. Friday
Journal: JAMA (1973)

<h3>To the Editor.—</h3> Pleuropericardial cysts rarely cause symptoms, and they are usually discovered as an incidental finding on a chest x-ray film. Their importance rests with the problem of distinguishing them from malignant tumors. Pleuropericardial cysts most commonly occur in the right cardiophrenic angle, but other sites such as the left cardiophrenic angle, the hila, and the anterior mediastinum have been reported. The majority are between 3 and 8 cm in diameter and on x-ray film they are seen as smooth, sharply demarcated, spherical or oval masses. If the cyst extends between the middle and lower lobes, the superior portion may be flattened so that the cyst assumes the shape of a teardrop.<sup>1</sup>In the past, a thoracotomy was necessary to prove that these asymptomatic masses were benign. We recently examined a patient with a right paracardiac mass and established its cystic nature by ultrasound examination; its benignity was
Selected Abstracts
Journal: JAMA (1976)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Interactions of Chrysotile and Benzopyrene in a Human Cell Culture Systems
Authors: R. E. Stephens, L. B. Joseph, F. B. Daniel, K. M. Schenck, H. A. I. Newman, P. D. Lipetz, J. R. Millette
Journal: Environmental Health Perspectives (1983)

The risk of lung cancer related to asbestos exposure has been shown to increase disproportionately by cigarette smoking, suggesting a synergistic effect. Differing lengths of NIEHS chrysotile with benzopyrene [B(a)P, B(e)P] (organic by-products of combustion) were applied on normal human fibroblasts (cell line CI) to test for cytotoxicity (survival determined by colony-forming efficiency), binding of benzopyrene to DNA, and the production of benzopyrene metabolites. At concentrations of 100 micrograms/mL, NIEHS short chrysotile was more cytotoxic than NIEHS intermediate chrysotile (3% and 17% survival, respectively); B(a)P and B(e)P concentrations up to and including 10 microM were not cytotoxic. Simultaneous application of NIEHS short chrysotile with B(a)P or B(e)P did not decrease survival synergistically. On the contrary, application of B(a)P simultaneously with NIEHS intermediate chrysotile resulted in increased survival over that of intermediate chrysotile alone (25% and 17% survival, respectively). There were low levels of B(a)P bound to DNA in the presence of NIEHS short chrysotile or NIEHS intermediate chrysotile. Measurable levels of B(a)P-DNA adducts were formed both in the absence and in the presence of each size of NIEHS chrysotile. However, there was no strong indication of a perturbation of the level of DNA-B(a)P binding following simultaneous administration of increasing levels of asbestos in addition to 1 microM hydrocarbon. The asbestos had no demonstrable influence on the level of B(a)P metabolism during the 24-hr period following simultaneous exposure of asbestos and hyrdocarbons.(ABSTRACT TRUNCATED AT 250 WORDS)
Results from a pilot of an innovative 4R Cancer Care Delivery Model in early breast cancer: Impact on timing and sequencing of guideline recommended care.
Authors: Christine B. Weldon, Julia Rachel Trosman, Claudia B. Perez, Swati Kulkarni, Seema Ahsan Khan, Nora M. Hansen, Valerie Nelson, Jennifer Stein, Melissa A. Simon, Cathy Spagnoli, Jennifer Tepper, Kay Pearson, William John Gradishar
Journal: Journal of Clinical Oncology (2018)

281 Background: Under the “NCI ASCO Teams” Project, we proposed a 4R Model of teamwork and patient self-management (Trosman JOP ’16). 4R = Right Info / Care / Patient / Time. It enables patient and care team to manage timing / sequencing of interdependent care with an innovative multimodality personalized 4R Care Project Plan. We piloted 4R at 3 centers (academic, community, safety net) and assessed impact on timing / sequencing of guideline based care. Methods: 4R Plans were administered to breast cancer patients stage 0-III Sept ’17 – Aug ’17. Clinical data for 185 patients who received 4R (4R cohort) were compared with a historical control cohort of comparable patients who received care pre-4R, Jun ’16 – May ’17. We used simple frequencies and Fisher’s exact test in analyses. Results: We improved timing / sequencing of 7 guideline recommended metrics (Table). Significant improvements were shown for care lacking in the control cohort. 4R improved rate of patients receiving genetic test results and fertility in a timely manner. Neoadjuvant therapy rate doubled, but low sample size precluded statistical conclusions. However, timing / sequencing of care needed prior to neoadjuvant therapy (eg fertility, flu shot) were significantly improved. Conclusions: The 4R model significantly improved timing / sequencing of guideline recommended care in early breast cancer. An ongoing 4R pilot at 12 additional cancer centers across the U.S. is continuing to accrue patients and focusing on other guideline-recommended metrics. [Table: see text]
Communicating with the public
Authors: C. P. Gilmore
Journal: JAMA (1970)

Biomedical investigators and science writers are in quite different fields and spend their days doing entirely different things, but they have at least one interest in common. They are both concerned with the transmission of information about science to the public. My involvement in the field grows out of a rather broad premise. I believe that in this imperfect but generally democratic society of ours, public understanding of scientific affairs is not a luxury, but a necessity. It has often been said that widespread awareness of the scientific, technological, and medical issues of our times is desirable because the public supplies much of the basic support for science and therefore has some right to know what it is supporting. But there is an even more important consideration: Only through an understanding of problems based on scientific and technological developments— from the ABM to the orally administered contraceptive to the research
Thyroid Thermogenesis
Authors: Isidore S. Edelman
Journal: New England Journal of Medicine (1974)

AWARENESS of the importance of "animal heat" in health and disease is rooted in antiquity. The discovery of oxygen and its role in metabolism of organic matter led to the realization in the mid-1800's that "animal heat" was derived from the controlled oxidation of foodstuffs. Microscopical studies of cellular organelles in the late 19th century established the existence of mitochondria, which in the last three decades have been identified as the site of oxidation of intracellular substrates and of conversion of this energy into phosphate ester bond energy of adenosine triphosphate (ATP). The primary biologic fuels, carbohydrates, fats and proteins . . .
Official Call to the Officers and Members of the American Medical Association to Attend the Interim Meeting of the House of Delegates in Nashville, Tenn, December 6-9, 1992
Journal: JAMA (1992)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The quality of mercy. Caring for patients with 'do not resuscitate' orders
Authors: D. P. Sulmasy
Journal: JAMA (1992)

<h3>Objective.</h3> —To assess (1) the effect of an ethics education intervention for medical house officers on practices surrounding "Do Not Resuscitate" (DNR) orders and (2) the association of DNR care with patient diagnosis and demographic variables. <h3>Design.</h3> —A 1-year randomized, controlled trial. <h3>Setting.</h3> —An urban, university teaching hospital. <h3>Participants.</h3> —Eighty-eight internal medicine house officers. <h3>Intervention.</h3> —House officers were arbitrarily assigned to four "firms." One firm was randomized to an extensive ethics education intervention (EI), one to a limited intervention, and two served as controls. <h3>Main Outcome Measures.</h3> —Charts of patients with DNR orders were reviewed for compliance with the hospital's DNR policy, which instructs that when DNR orders are written there should be (1) an attending signature, (2) documentation of reasons, (3) appropriate consent, and (4) attention to 11 concurrent care concerns (CCCs) (eg, the appropriateness of intubation, tube feedings, hospice). <h3>Results.</h3> —Thirty-nine charts were reviewed before the intervention and 57 after. The number of CCCs per DNR order fell among patients cared for by controls (1.9 to 1.0,<i>P</i>&lt;.05) and rose among patients cared for by the El group (0.9 to 3.8,<i>P</i>&lt;.05). Compliance with the DNR policy varied among patients with differing diagnoses. "Do Not Resuscitate" orders were signed less frequently (<i>P</i>=.01) for patients with the acquired immunodeficiency syndrome (AIDS) (65%) compared with patients who had other diagnoses (85%) or malignancy (91%). Similarly, appropriate consent was recorded for 59% of patients with AIDS, 83% of others, and 85% of those with malignancy (<i>P</i>&lt;.05). The number of CCCs per DNR was 0.7 for AIDS, 1.4 for others, and 2.4 for malignancy (<i>P</i>&lt;.05). In multivariate regression analysis, house officer ethics education and patient diagnosis, but not patient gender, age, race, or insurance status, were predictors of the number of CCCs per DNR. <h3>Conclusions.</h3> —(1) An extensive ethics education intervention can improve care for DNR patients, especially with respect to CCCs. (2) In this setting, quality of care for DNR patients varied systematically with diagnosis. These results have implications for the design and implementation of ethics education programs. (<i>JAMA</i>. 1992;267:682-686)
Reply
Authors: Robert M. Fine, Dwight R. Weathers
Journal: British Journal of Dermatology (1980)

Journal Article Reply Get access Robert M. Fine, Robert M. Fine Winn Way Professional Building, Decatur, Georgia 30030 Search for other works by this author on: Oxford Academic Google Scholar Dwight R. Weathers Dwight R. Weathers Winn Way Professional Building, Decatur, Georgia 30030 Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 103, Issue 6, 1 December 1980, Pages 705–707, https://doi.org/10.1111/j.1365-2133.1980.tb01699.x Published: 01 December 1980
AMERICAN NEUROLOGICAL ASSOCIATION
Journal: JAMA (1913)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Entrectinib Shows Pediatric Potential
Journal: Cancer Discovery (2019)

Abstract According to preliminary data from the phase I/Ib STARTRK-NG trial, the investigational multikinase inhibitor entrectinib showed efficacy in children and adolescents with CNS and other tumor types harboring NTRK1/2/3, ROS1, or ALK fusions. Durable responses were seen even in CNS tumors such as high-grade glioma.
Normal cardiac sympathetic innervation in patients with neurocardiac syncope
Authors: E.D. Engelstein, G.O. Hutchins, S.G. Sawada, S. Straka, R. Sehra, R.L. Fain, R. Amaravadi, J.E. Ofgin, W.M. Miles, D.P. Zipes
Journal: Journal of the American College of Cardiology (1998)
Correction: Vitamin D3 in osteoporosis
Authors: M Ostrowski, Cunningham Tj, Donavan Olson
Journal: BMJ (1980)

had low toxicity and gave an overall response rate of 73%0.In the multicentre study in 153 patients there were no drug-related deaths.We conclude that intracavitary bleomycin is well tolerated and is effective as palliative treatment for malignant effusions, preventing the need for frequent aspiration of accumulated fluid.Because of its lack of haematological toxicity it may be used safely in the already leucopenic patient.
Commentary
Authors: David Watkins
Journal: British Journal of Sports Medicine (2001)

Objectives-To investigate the amount of regular activity and time spent in sedentary occupations in children aged 7-9 years.Sex diVerences in levels of activity and time and facilities for physical education at school were also examined.Methods-A 10% sample of Dublin National Schools were selected.Parents of children in second class were surveyed.The questionnaire used was a modification of the Modifiable Activity Questionnaire for Adolescents.Teachers of second class were questioned about the time and facilities for physical education in schools.Results-Some 39% of children were participating in hard exercise for at least 20 minutes three or more times a week, with fewer girls (28%) than boys (53%) contributing to this result.A further 57% of children were engaging in at least 20 minutes of light exercise three or more times a week, with no sex diVerences.Estimated energy expenditure in regular activity was higher in boys than girls.Most (78%) of the children were spending one to three hours a day sedentary in front of a screen.Conclusions-This study provides comprehensive data on physical activity levels in Dublin schoolchildren aged 7-9 years.The amount of inactivity is of concern.Even at this young age, boys are reported to participate in more physical activity than girls.
Operating Standards in Methadone Maintenance Programs
Journal: JAMA (1971)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Size does matter: comparison of activity between anti-EGFR and anti-VEGF based-treatment in RAS wild type colorectal cancer patients, stratified by size of metastatic involvement
Authors: M. Del Prete, R. Giampieri, A. Bittoni, A. Bruschi, M. Caramanti, R. Bisonni, M. Di Pietro Paolo, A. Lanese, R.R. Silva, L. Giustini, R. Berardi
Journal: Annals of Oncology (2017)
Josef Jadassohn (1863-1936) Dermatologist
Journal: JAMA (1969)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
From the Centers for Disease Control and Prevention. International decade for natural disaster reduction
Journal: JAMA (1994)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Greed
Authors: R. Crawshaw
Journal: BMJ (1996)

arise as much from their "dyslipophobia" as from the disturbed eating pattern.1'But gluttony need not apply only to food, there are also gluttons for work.Satiation also can be overdone.We should all be capable of satia- tion, but not too easily and not all the time.1 Holy Bible (New International Version).Proverbs xxiii,2.
Correction: Bladder cancer as a prescribed industrial disease
Journal: BMJ (1980)

Dr W J Appleyard).It is right and proper for the RHAs to hold the contracts of consultants in hospitals outside the teaching areas, and I do not need to enumerate again the reasons.DHA(T)s, however, have different needs as regards staffing levels, number of junior staff, and indeed constitution of appointment committees.Again, the BMA must urge the Secretary of State to think this out clearly, and ensure that medical education is properly looked after.This would include the DHA(T)s holding their consultant contracts.Finally, Sir, paragraph 35 refers to the extent to which students are now taught in non-designated areas or districts.The Secretary of State seems to be under the same delusion as the BMA.There are two types of
PLoS Medicine Issue Image | Vol. 2(12) December 2005
Journal: PLoS Medicine (2005)

Dr. Samantha Krukowski is a practicing artist and assistant professor in the production area of the Department of Radio-TV-Film at the University of Texas at Austin, where she teaches courses in experimental media. Dr. Krukowski received a B.A. in political science at Barnard College/Columbia University in 1988, an M.A. in art history at Washington University in 1992, an M.Arch. in architecture at the University of Texas at Austin in 1997, and a Ph.D. in art history at the University of Texas at Austin in 1999. More information about Dr. Krukowski and her work can be found at http://www.rasa.net. Image Credit: Dr. Samantha Krukowski (http://www.rasa.net)
Drug fever
Authors: B. A. Lipsky
Journal: JAMA (1981)

Most medications can cause fever, with or without concomitant clinical manifestations. The fever may arise from the drug's pharmacologic action, its effects on thermoregulation, a local complication following parenteral administration, or an idiosyncratic response. The most common mechanism is probably an immunologic reaction mediated by drug-induced antibodies. Drug fever may have any pattern; it typically occurs after seven to ten days of treatment and usually resolves within 48 hours of discontinuing the administration. Failure to diagnose drug fever may lead to inappropriate and potentially harmful diagnostic and therapeutic interventions. In suspected cases, it is necessary to discontinue administration of all potentially causative medicines, together or sequentially. Rechallenge with the offending agent will usually cause recurrence of fever within a few hours, confirming the diagnosis. (<i>JAMA</i>1981;245:851-854)